BioMedLib Search Engine [ goto HOMEPAGE ]

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Identification of CD133-positive radioresistant cells in atypical teratoid/rhabdoid tumor.

Atypical teratoid/rhabdoid tumor (AT/RT) is an extremely malignant neoplasm in the central nervous system (CNS) which occurs in infancy and childhood.

[MeSH-major] Antigens, CD / immunology. Glycoproteins / immunology. Peptides / immunology. Radiation Tolerance. Rhabdoid Tumor / diagnosis

Genetic Alliance. consumer health - Rhabdoid tumor.

COS Scholar Universe. author profiles.

NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

The Lens. Cited by Patents in .

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Oncogene. 2007 Mar 1;26(10):1459-67 [16936774.001]

[Cites] Nature. 2007 Jan 4;445(7123):111-5 [17122771.001]

[Cites] Int J Radiat Biol. 2007 Mar;83(3):153-9 [17378523.001]

[Cites] Cancer Res. 2007 May 1;67(9):4010-5 [17483311.001]

[Cites] Int J Cancer. 2007 Dec 1;121(11):2547-55 [17680560.001]

[Cites] Eur Neuropsychopharmacol. 2008 Feb;18(2):128-40 [17566715.001]

[Cites] Clin Cancer Res. 2008 Jan 1;14(1):123-9 [18172261.001]

[Cites] Nat Rev Cancer. 2006 Dec;6(12):909-23 [17128209.001]

[Cites] Acta Neuropathol. 2000 May;99(5):482-8 [10805090.001]

[Cites] Nature. 2002 Jan 24;415(6870):436-42 [11807556.001]

[Cites] J Pediatr Hematol Oncol. 2002 Jun-Jul;24(5):337-42 [12142780.001]

[Cites] Mol Cancer Ther. 2002 Jun;1(8):639-49 [12479224.001]

[Cites] Cancer Res. 2003 Sep 15;63(18):5821-8 [14522905.001]

[Cites] Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15178-83 [14645703.001]

[Cites] J Clin Oncol. 2004 Jul 15;22(14):2877-84 [15254056.001]

[Cites] N Engl J Med. 1989 Sep 28;321(13):906 [2770830.001]

[Cites] Genes Chromosomes Cancer. 1992 Sep;5(2):104-8 [1381945.001]

[Cites] J Neurosurg. 1996 Jul;85(1):56-65 [8683283.001]

[Cites] Genes Chromosomes Cancer. 1996 Jun;16(2):94-105 [8818656.001]

[Cites] Acta Neurochir (Wien). 1997;139(10):961-8; discussion 968-9 [9401657.001]

[Cites] Nature. 1998 Jul 9;394(6689):203-6 [9671307.001]

[Cites] Int J Radiat Oncol Biol Phys. 1998 Jul 15;41(5):1013-9 [9719110.001]

[Cites] Am J Surg Pathol. 1998 Sep;22(9):1083-92 [9737241.001]

[Cites] Cancer Res. 1999 Jan 1;59(1):74-9 [9892189.001]

[Cites] Mod Pathol. 2005 Jun;18(6):769-78 [15776015.001]

[Cites] Br J Cancer. 2005 Jun 20;92(12):2185-9 [15928664.001]

[Cites] Radiother Oncol. 2005 Aug;76(2):119-22 [16024119.001]

[Cites] Cancer. 2005 Nov 15;104(10):2156-67 [16220552.001]

[Cites] Int J Radiat Oncol Biol Phys. 2006 Mar 15;64(4):1038-43 [16406394.001]

[Cites] Br J Pharmacol. 2006 Jul;148(5):587-98 [16702990.001]

[Cites] Trends Biochem Sci. 2006 Jul;31(7):402-10 [16774833.001]

[Cites] Exp Cell Res. 2006 Oct 15;312(17):3370-8 [16934800.001]

[Cites] Biochim Biophys Acta. 2006 Oct;1763(10):1090-7 [16997395.001]

[Cites] J Immunol. 2006 Nov 1;177(9):6199-206 [17056549.001]

[Cites] Int J Radiat Oncol Biol Phys. 2006 Dec 1;66(5):1498-505 [17126209.001]

[Cites] Nature. 2004 Nov 18;432(7015):396-401 [15549107.001]

[Cites] J Clin Oncol. 2005 Mar 1;23(7):1491-9 [15735125.001]

[Cites] Cancer. 2005 Apr 25;105(2):65-70 [15690353.001]

[Cites] Acta Radiol. 2005 Feb;46(1):89-96 [15841745.001]

[Cites] Biochem Biophys Res Commun. 2005 Jun 10;331(3):851-8 [15865941.001]

[Cites] Nat Med. 2005 May;11(5):484-90 [15864314.001]

[Cites] Nature. 2006 Dec 7;444(7120):756-60 [17051156.001]

[Cites] Int J Radiat Oncol Biol Phys. 2007 Jan 1;67(1):1-5 [17084552.001]

[Cites] Nat Genet. 2007 Jan;39(1):99-105 [17143283.001]

[Cites] Biochem Biophys Res Commun. 2007 Apr 20;355(4):855-9 [17307142.001]

(PMID = 18509505.001).

[ISSN] 1932-6203

[Journal-full-title] PloS one

[ISO-abbreviation] PLoS ONE

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / AC133 antigen; 0 / Antigens, CD; 0 / Glycoproteins; 0 / Peptides; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / RNA, Small Interfering

[Other-IDs] NLM/ PMC2396792

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid/rhabdoid tumor of the central nervous system associated with congenital cataract.

Atypical teratoid /rhabdoid tumor (AT/RT) of the central nervous system is a rare but highly aggressive neoplasm that usually affects young children and infants and follows a rapidly fatal course.

[MeSH-major] Central Nervous System Neoplasms / diagnosis. Central Nervous System Neoplasms / pathology. Rhabdoid Tumor / diagnosis. Rhabdoid Tumor / pathology. Teratoma / diagnosis. Teratoma / pathology

[MeSH-minor] Cataract / complications. Cataract / congenital. Central Nervous System / pathology. Fatal Outcome. Humans. Infant. Male

Genetic Alliance. consumer health - Rhabdoid tumor.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 18723966.001).

[ISSN] 0377-4929

[Journal-full-title] Indian journal of pathology & microbiology

[ISO-abbreviation] Indian J Pathol Microbiol

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] India

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Childhood atypical teratoid rhabdoid tumor of the central nervous system: a meta-analysis of observational studies.

PURPOSE: Therapy for central nervous system (CNS) atypical teratoid rhabdoid tumor (ATRT) is controversial.

RESULTS: The median OS for patients treated with multiagent chemotherapy (n=79) was 17.3 months (range, 1.5-93 mo); unrelated to age at diagnosis, sex, tumor site, and extent of resection.

Patients (n=30) treated with intrathecal (IT) chemotherapy had significantly higher 2-year OS [64% (95% confidence interval, 46.5-82.0) vs. 17.3% (95% confidence interval, 5.4-29.3); P<0.0001] and lower prevalence of distant CNS metastasis compared with those without IT therapy (n=49) (20% vs. 59.2%; P=0.001).

CONCLUSIONS: Despite dismal OS, multimodal therapy can induce remission even in metastatic CNS ATRT with partial resection.

[MeSH-major] Brain Neoplasms / epidemiology. Rhabdoid Tumor / epidemiology. Teratoma / epidemiology

[MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Child, Preschool. Cisplatin / administration & dosage. Combined Modality Therapy. Craniotomy. Cyclophosphamide / administration & dosage. Dactinomycin / administration & dosage. Doxorubicin / administration & dosage. Etoposide / administration & dosage. Fatal Outcome. Female. Humans. Infant. Infant, Newborn. Injections, Spinal. Kaplan-Meier Estimate. Male. Prognosis. Prospective Studies. Spinal Neoplasms / diagnosis. Spinal Neoplasms / drug therapy. Spinal Neoplasms / epidemiology. Spinal Neoplasms / radiotherapy. Spinal Neoplasms / surgery. Treatment Outcome. Vincristine / administration & dosage

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

COS Scholar Universe. author profiles.

Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

Hazardous Substances Data Bank. DOXORUBICIN .

Hazardous Substances Data Bank. ETOPOSIDE .

Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .

Hazardous Substances Data Bank. DACTINOMYCIN .

Hazardous Substances Data Bank. VINCRISTINE .

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 19707161.001).

[ISSN] 1536-3678

[Journal-full-title] Journal of pediatric hematology/oncology

[ISO-abbreviation] J. Pediatr. Hematol. Oncol.

[Language] eng

[Publication-type] Case Reports; Journal Article; Meta-Analysis

[Publication-country] United States

[Chemical-registry-number] 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; Q20Q21Q62J / Cisplatin

   

Advertisement

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Giant lumbar paraspinal atypical teratoid/rhabdoid tumor in a child.

Atypical teratoid/rhabdoid tumor (AT/RT) is a highly aggressive and uncommon tumor of the central nervous system, primarily affecting young children.

[MeSH-major] Rhabdoid Tumor / pathology. Spinal Neoplasms / pathology. Teratoma / pathology

Genetic Alliance. consumer health - Rhabdoid tumor.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 20160373.001).

[ISSN] 1998-4138

[Journal-full-title] Journal of cancer research and therapeutics

[ISO-abbreviation] J Cancer Res Ther

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] India

[Chemical-registry-number] 0 / Antineoplastic Agents

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Cribriform neuroepithelial tumor (CRINET): a nonrhabdoid ventricular tumor with INI1 loss and relatively favorable prognosis.

Atypical teratoid/rhabdoid tumors are malignant embryonal tumors characterized by the presence of rhabdoid cells, genetic alterations affecting the SMARCB1 gene (hSNF5/INI1), and a poor prognosis.

Whether INI1 plays a role in the pathogenesis of other central nervous system tumors is uncertain.

Histological and immunohistochemical features did not correspond to established tumor types, including atypical teratoid/rhabdoid tumors, medulloepithelioma, choroid plexus carcinoma, and ependymoma.

We suggest that cribriform neuroepithelial tumor (CRINET) is a nonrhabdoid ventricular tumor that shows loss of tumoral INI1 protein and has a relatively favorable prognosis.

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 19915490.001).

[ISSN] 1554-6578

[Journal-full-title] Journal of neuropathology and experimental neurology

[ISO-abbreviation] J. Neuropathol. Exp. Neurol.

[Language] eng

[Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / SMARCB1 protein, human; 0 / Transcription Factors

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells.

Central nervous system (CNS) atypical teratoid/rhabdoid tumours (AT/RT) are among the paediatric malignant tumours with the worst prognosis and fatal outcome.

Moreover, we found IGF-I and IGF-II mRNA in BT-16 CNS AT/RT cells and IGF-II mRNA in BT-12 CNS AT/RT cells, and autophosphorylated IGF-IR in both cell lines, indicating the potential presence of an autocrine/paracrine IGF-I/II/IGF-IR loop in CNS AT/RT.

IGF-IR antisense oligonucleotide treatment of human CNS AT/RT cells resulted in significant down-regulation of IGF-IR mRNA and protein expression, induction of apoptosis, and chemosensitisation to doxorubicin and cisplatin.

These studies provide evidence for the influence of IGF-IR on cellular responses to chemotherapy and raise the possibility that curability of selected CNS AT/RT may be improved by pharmaceutical strategies directed towards the IGF-IR.

[MeSH-major] Apoptosis / drug effects. Central Nervous System Neoplasms / drug therapy. Oligoribonucleotides, Antisense / therapeutic use. Receptor, IGF Type 1 / drug effects. Rhabdoid Tumor / drug therapy. Teratoma / drug therapy

COS Scholar Universe. author profiles.

Cellosaurus - a cell line knowledge resource. culture/stock collections - Cellosaurus - a cell line knowledge resource .

Cellosaurus - a cell line knowledge resource. culture/stock collections - Cellosaurus - a cell line knowledge resource .

Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

Hazardous Substances Data Bank. DOXORUBICIN .

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 17446062.001).

[ISSN] 0959-8049

[Journal-full-title] European journal of cancer (Oxford, England : 1990)

[ISO-abbreviation] Eur. J. Cancer

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Oligoribonucleotides, Antisense; 67763-96-6 / Insulin-Like Growth Factor I; 80168379AG / Doxorubicin; EC 2.7.10.1 / Receptor, IGF Type 1; Q20Q21Q62J / Cisplatin

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid/rhabdoid tumor involving cerebrospinal fluid: a case report.

BACKGROUND: Atypical teratoid/rhabdoid tumor (AT/RT) is a rare, aggressive tumor of the central nervous system.

It is important for pathologists to recognize the cytomorphologic features of AT/RT in the CSF of patients with this tumor to help determine prognosis and disease progression.

[MeSH-major] Rhabdoid Tumor / cerebrospinal fluid. Rhabdoid Tumor / pathology. Spinal Neoplasms / cerebrospinal fluid. Spinal Neoplasms / pathology. Teratoma / cerebrospinal fluid. Teratoma / pathology

Genetic Alliance. consumer health - Rhabdoid tumor.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 21053577.001).

[ISSN] 0001-5547

[Journal-full-title] Acta cytologica

[ISO-abbreviation] Acta Cytol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Diffusion-weighted imaging of an atypical teratoid/rhabdoid tumor of the cervical spine.

Spinal atypical teratoid/rhabdoid tumor (AT/RT) is a rare, aggressive malignant neoplasm of the central nervous system usually seen in young children and infants.

High signal on DWI and low apparent diffusion coefficients may represent high cellularity of the tumor.

These findings indicated a highly malignant tumor.

[MeSH-major] Cervical Vertebrae. Diffusion Magnetic Resonance Imaging / methods. Rhabdoid Tumor / pathology. Spinal Cord Neoplasms / pathology. Teratoma / pathology

[MeSH-minor] Child. Diagnosis, Differential. Humans. Immunohistochemistry. Male

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Neck Injuries and Disorders.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 19783876.001).

[ISSN] 1880-2206

[Journal-full-title] Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine

[ISO-abbreviation] Magn Reson Med Sci

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Japan

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Immunohistochemical analysis of INI1 protein in malignant pediatric CNS tumors: Lack of INI1 in atypical teratoid/rhabdoid tumors and in a fraction of primitive neuroectodermal tumors without rhabdoid phenotype.

Immunohistochemical lack of nuclear INI1 protein expression has been recently described as characteristic finding in atypical teratoid/rhabdoid tumors (AT/RTs), and has been suggested as useful marker to distinguish AT/RTs from other malignant pediatric central nervous system (CNS) tumors.

In this study, we examined a large series of malignant pediatric CNS tumors to determine the immunohistochemical expression of INI1 protein in different malignant pediatric tumor entities.

Archival paraffin-embedded biopsy specimens of 289 malignant pediatric CNS tumors including medulloblastomas, supratentorial primitive neuroectodermal tumors, glioblastomas, anaplastic astrocytomas, anaplastic ependymomas, choroid plexus carcinomas, germ cell tumors, and AT/RTs were analyzed immunohistochemically for expression of nuclear INI1 protein.

Seventeen of the 26 tumors showed morphologically characteristic features of AT/RTs, whereas 9 embryonal tumors did not display rhabdoid features.

Tumors without rhabdoid phenotype but lack of INI1 showed an aggressive clinical course and poor response to conventional treatment regimens.

Furthermore, a certain number of embryonal tumors without rhabdoid features but lack of INI1 protein and aggressive biologic behavior can be detected.

We conclude that INI1 protein analysis should be routinely performed in all malignant pediatric embryonal CNS tumors to detect cases with lack of INI1 protein, because patients with these tumors are likely to benefit from intensified treatment.

[MeSH-major] Biomarkers, Tumor / analysis. Brain Neoplasms / metabolism. Chromosomal Proteins, Non-Histone / metabolism. DNA-Binding Proteins / metabolism. Neuroectodermal Tumors, Primitive / metabolism. Rhabdoid Tumor / metabolism. Teratoma / metabolism. Transcription Factors / metabolism

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 17063089.001).

[ISSN] 0147-5185

[Journal-full-title] The American journal of surgical pathology

[ISO-abbreviation] Am. J. Surg. Pathol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / SMARCB1 protein, human; 0 / Transcription Factors

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Clinical and pathological features of paediatric malignant rhabdoid tumours.

BACKGROUND: Malignant rhabdoid tumours (MRT) and their central nervous system (CNS) counterparts atypical teratoid/rhabdoid tumours (ATRT) are rare, highly aggressive malignant neoplasms of childhood.

[MeSH-major] Rhabdoid Tumor / pathology. Teratoma / pathology

[MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / analysis. Child. Combined Modality Therapy. Female. Humans. Immunoenzyme Techniques. Infant. Male. Neoplasm Staging. Prognosis. Radiotherapy. Retrospective Studies. Survival Rate. Treatment Outcome

COS Scholar Universe. author profiles.

NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Copyright] Copyright 2009 Wiley-Liss, Inc.

(PMID = 19653294.001).

[ISSN] 1545-5017

[Journal-full-title] Pediatric blood & cancer

[ISO-abbreviation] Pediatr Blood Cancer

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Comparative analysis of germ cell transcription factors in CNS germinoma reveals diagnostic utility of NANOG.

To assess the diagnostic utility of NANOG in central nervous system (CNS) germ cell tumors, we analyzed its expression by immunohistochemistry in a series of 12 CNS germinomas and compared its expression with other stem cell markers.

Strong nuclear expression of NANOG was demonstrated in >90% of the tumor cells in all cases.

NANOG was not detected in tumor types frequently considered in the differential diagnosis of CNS germinoma: pineoblastoma, primitive neuroectodermal tumors, medulloblastoma, lymphoma, pituitary adenoma, atypical teratoid/rhabdoid tumor, Langerhans cell histiocytosis, and gliomas.

These findings demonstrate that NANOG is a sensitive and specific marker of CNS germinoma.

These findings also suggest a potential biologic role for NANOG in maintenance of CNS germinoma.

[MeSH-minor] Adolescent. Adult. Alkaline Phosphatase / metabolism. Biomarkers, Tumor / metabolism. Cell Nucleus / metabolism. Child. HMGB Proteins / metabolism. Humans. Isoenzymes / metabolism. Octamer Transcription Factor-3 / metabolism. SOXB1 Transcription Factors. Transcription Factors / metabolism

Genetic Alliance. consumer health - Germinoma.

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

COS Scholar Universe. author profiles.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 17122519.001).

[ISSN] 0147-5185

[Journal-full-title] The American journal of surgical pathology

[ISO-abbreviation] Am. J. Surg. Pathol.

[Language] eng

[Grant] United States / NINDS NIH HHS / NS / NS047213

[Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / HMGB Proteins; 0 / Homeodomain Proteins; 0 / Isoenzymes; 0 / NANOG protein, human; 0 / Octamer Transcription Factor-3; 0 / POU5F1 protein, human; 0 / SOX2 protein, human; 0 / SOXB1 Transcription Factors; 0 / Transcription Factors; 0 / germ-cell AP isoenzyme; EC 3.1.3.1 / Alkaline Phosphatase

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Ultrastructural evidence of ependymal differentiation in a genetically proven atypical teratoid/rhabdoid tumor.

INTRODUCTION: We describe a case of genetically proven atypical teratoid/rhabdoid tumor (ATRT), showing ultrastructural evidence of ependymal differentiation.

CONCLUSION: This finding supports the concept that ATRTs as the majority of central nervous system embryonal tumors may derive from an immature and pluripotent neuroectodermal cell capable of differentiating along multiple lineages.

[MeSH-major] Cerebral Ventricle Neoplasms / ultrastructure. Ependyma / ultrastructure. Rhabdoid Tumor / ultrastructure. Teratoma / ultrastructure

Genetic Alliance. consumer health - Rhabdoid tumor.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Cancer Res. 2005 May 15;65(10 ):4012-9 [15899790.001]

[Cites] Mod Pathol. 2004 Jun;17(6):679-83 [15105808.001]

[Cites] J Neurooncol. 2007 Sep;84(2):217-22 [17431546.001]

[Cites] Neuro Oncol. 2006 Jan;8(1):79-82 [16443951.001]

[Cites] Brain Tumor Pathol. 2008;25(2):79-83 [18987833.001]

[Cites] Cancer Cell. 2005 Apr;7(4):294-5 [15837618.001]

[Cites] AJNR Am J Neuroradiol. 1993 Jan-Feb;14 (1):107-15 [8427070.001]

[Cites] Brain Pathol. 2003 Jul;13(3):409-14 [12946029.001]

[Cites] J Pediatr Hematol Oncol. 2002 Jun-Jul;24(5):337-42 [12142780.001]

[Cites] Neurosurg Focus. 2006 Jan 15;20(1):E11 [16459991.001]

[Cites] Oncogene. 2002 Aug 8;21(34):5193-203 [12149641.001]

[Cites] J Neuropathol Exp Neurol. 2008 Mar;67(3):177-88 [18344909.001]

[Cites] J Child Neurol. 2008 Oct;23(10):1195-204 [18952586.001]

[Cites] Pathology. 2008 Dec;40(7):664-70 [18985520.001]

[Cites] Am J Surg Pathol. 1998 Sep;22(9):1083-92 [9737241.001]

[Cites] Ultrastruct Pathol. 1997 Jul-Aug;21(4):369-78 [9206002.001]

(PMID = 19554334.001).

[ISSN] 1433-0350

[Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

[ISO-abbreviation] Childs Nerv Syst

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Intensive induction chemotherapy followed by high dose chemotherapy with autologous hematopoietic progenitor cell rescue in young children newly diagnosed with central nervous system atypical teratoid rhabdoid tumors.

BACKGROUND: Central nervous system (CNS) atypical teratoid rhabdoid tumors (AT/RT) are rare tumors of childhood with a dismal prognosis.

Historically, surgery and standard dose chemotherapy have resulted in a median survival of 8.5 months from diagnosis.

METHODS: Thirteen children newly diagnosed with CNS AT/RT were treated with either the "Head Start I" (HS I) or "Head Start II" (HS II) regimens.

There are presently three event-free survivors 42+, 54+, and 67+ months following diagnosis; none received RT.

CONCLUSION: Three of seven children with CNS AT/RT treated on HS II have experienced long term remissions.

Long term survival can be achieved in a subset of young children with CNS AT/RT following resection with the use of multi-drug chemotherapy including high dose methotrexate and myeloablative chemotherapy without radiation therapy (RT).

[MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Brain Neoplasms / therapy. Hematopoietic Stem Cell Transplantation. Rhabdoid Tumor / therapy. Teratoma / therapy

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

COS Scholar Universe. author profiles.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 18381756.001).

[ISSN] 1545-5017

[Journal-full-title] Pediatric blood & cancer

[ISO-abbreviation] Pediatr Blood Cancer

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Renal medullary carcinoma: rhabdoid features and the absence of INI1 expression as markers of aggressive behavior.

Renal medullary carcinoma is a rare, well-recognized highly aggressive tumor of varied histopathology, which occurs in young patients with sickle cell trait or disease.

Rhabdoid elements, occasionally seen in high-grade renal tumors including renal medullary carcinoma, possibly represent a pathologic marker of aggressive behavior.

Loss of this factor in mice results in aggressive rhabdoid tumors or lymphomas.

In humans, the loss of INI1 expression has been reported in pediatric renal rhabdoid tumors, central nervous system atypical teratoid/rhabdoid tumors and epithelioid sarcomas, a possible primary soft tissue rhabdoid tumor.

This study compares five renal medullary carcinomas with 10 high-grade renal cell carcinomas (five with rhabdoid features), two urothelial carcinomas and two pediatric renal rhabdoid tumors.

All five renal medullary carcinomas, irrespective of histopathology, showed complete loss of INI1 expression similar to that seen in pediatric renal rhabdoid tumors.

In contrast, all renal cell carcinomas or urothelial carcinomas, including those with histological rhabdoid features, expressed INI1.

Clinically, all five of the patients with renal medullary carcinoma and the two patients with rhabdoid tumors presented with extra-renal metastases at the time of diagnosis.

This study demonstrates that renal medullary carcinoma and renal rhabdoid tumor share a common molecular/genetic alteration, which is closely linked to their aggressive biological behavior.

However, the absence of INI1 expression is not necessarily predictive of rhabdoid histopathology but remains associated with aggressive behavior in renal medullary carcinoma.

[MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Renal Cell / pathology. Chromosomal Proteins, Non-Histone / biosynthesis. DNA-Binding Proteins / biosynthesis. Kidney Neoplasms / pathology. Rhabdoid Tumor / pathology. Transcription Factors / biosynthesis

MedlinePlus Health Information. consumer health - Kidney Cancer.

The Lens. Cited by Patents in .

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 18327209.001).

[ISSN] 0893-3952

[Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

[ISO-abbreviation] Mod. Pathol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / SMARCB1 protein, human; 0 / Transcription Factors

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

BACKGROUND/AIMS: Medulloblastomas (MBs), atypical teratoid rhabdoid tumors (AT/RTs) and central nervous system primitive neuroectodermal tumors (PNETs) are aggressive embryonal brain neoplasms in children with overlapping histological features but with different pathogenetic pathways.

The immunohistochemical expression of EGFR and HER-2 was correlated to histology, expression of the Ki-67/MIB-1 proliferative index, p53 tumor suppressor oncoprotein and prognosis.

[MeSH-minor] Adolescent. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Infant, Newborn. Ki-67 Antigen / metabolism. Male. Prognosis. Retrospective Studies. Risk Factors. Tumor Suppressor Protein p53 / metabolism

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Copyright] Copyright © 2010 S. Karger AG, Basel.

(PMID = 20962551.001).

[ISSN] 1423-0305

[Journal-full-title] Pediatric neurosurgery

[ISO-abbreviation] Pediatr Neurosurg

[Language] eng

[Publication-type] Journal Article

[Publication-country] Switzerland

[Chemical-registry-number] 0 / Ki-67 Antigen; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / ERBB2 protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-2

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid/rhabdoid tumor in an infant conceived by in vitro fertilization.

BACKGROUND: Atypical teratoid/rhabdoid tumor (ATsRT) is a rare tumor and extremely aggressive embryonal neoplasm of the central nervous system.

[MeSH-major] Brain Neoplasms / pathology. Diseases in Twins / pathology. Fertilization in Vitro. Rhabdoid Tumor / pathology. Teratoma / pathology

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Brain Tumors.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Neuropadiatrie. 1973 Jan;4(1):46-63 [4739778.001]

[Cites] J Neurosurg. 2005 Nov;103(5 Suppl):451-3 [16302619.001]

[Cites] AJR Am J Roentgenol. 1990 Sep;155(3):587-93 [2167004.001]

[Cites] Br J Cancer. 2005 Oct 31;93(9):1053-6 [16234814.001]

[Cites] Am J Epidemiol. 1996 May 15;143(10):996-1001 [8629618.001]

[Cites] Mol Hum Reprod. 2002 Nov;8(11):1035-41 [12397217.001]

[Cites] Obstet Gynecol. 2004 Jun;103(6):1154-63 [15172847.001]

[Cites] Lancet. 1998 Aug 8;352(9126):452-3 [9708757.001]

[Cites] Lancet. 1999 Nov 6;354(9190):1579-85 [10560671.001]

[Cites] J Neurosurg. 1996 Jul;85(1):56-65 [8683283.001]

[Cites] Surg Neurol. 1984 Jun;21(6):597-609 [6372141.001]

[Cites] Fertil Steril. 2005 Sep;84(3):605-10 [16169392.001]

[Cites] Diagn Cytopathol. 2004 Jul;31(1):60-3 [15236268.001]

[Cites] Hum Reprod. 2005 Feb;20(2):328-38 [15567881.001]

[Cites] Childs Nerv Syst. 1989 Apr;5(2):55-9 [2660986.001]

[Cites] Hum Reprod. 2000 Mar;15(3):604-7 [10686204.001]

[Cites] Pediatr Neurosurg. 2002 Nov;37(5):267-70 [12411720.001]

[Cites] Fertil Steril. 2004 Apr;81(4):1083-91 [15066468.001]

[Cites] Hum Reprod. 1997 Dec;12(12):2784-91 [9455853.001]

[Cites] Childs Nerv Syst. 2000 Aug;16(8):501-2 [11007501.001]

[Cites] N Engl J Med. 1982 Sep 23;307(13):820 [6287262.001]

[Cites] Pediatr Int. 2008 Dec;50(6):831-2 [19067904.001]

[Cites] J Neurosurg. 2007 May;106(5 Suppl):418; author reply 418-9 [17566216.001]

[Cites] Cancer. 2000 Jun 15;88(12):2845-7 [10870070.001]

[Cites] Cancer. 1995 Dec 1;76(11):2372-4 [8635045.001]

[Cites] Lancet. 1991 Oct 12;338(8772):955 [1681306.001]

[Cites] J Ultrasound Med. 2001 Dec;20(12):1369-75 [11762550.001]

[Cites] J Natl Cancer Inst. 1987 May;78(5):797-804 [3471992.001]

[Cites] Eur J Cancer. 2005 Mar;41(5):715-24; discussion 725-6 [15763647.001]

[Cites] Med Pediatr Oncol. 1994;23(2):133-5 [8202036.001]

[Cites] Hum Reprod. 2001 Nov;16(11):2451-8 [11679537.001]

[Cites] Lancet. 1990 Dec 22-29;336(8730):1577 [1979385.001]

(PMID = 19937253.001).

[ISSN] 1433-0350

[Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

[ISO-abbreviation] Childs Nerv Syst

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] A child with atypical teratoid/rhabdoid tumour of the posterior cranial fossa.

Primary central nervous system (CNS) atypical teratoid/rhabdoid tumours (ATRT) are highly malignant neoplasms which usually present in infancy or early childhood.

Although ATRT may arise anywhere within the CNS, the majority (approximately two-thirds) arise in the cerebellum or posterior fossa, and the remainder in the cerebrum.

We described the imaging characteristics of CNS ATRT in the posterior cranial fossa of a 14-month-old boy.

[MeSH-major] Cranial Fossa, Posterior. Rhabdoid Tumor / diagnosis. Skull Base Neoplasms / diagnosis. Teratoma / diagnosis

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 19122937.001).

[ISSN] 0037-5675

[Journal-full-title] Singapore medical journal

[ISO-abbreviation] Singapore Med J

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Singapore

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid/rhabdoid tumors: imaging findings of two cases and review of the literature.

Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant embryonal central nervous system (CNS) tumor, manifesting in children, and composed of rhabdoid cells, with or without fields resembling a classical primitive neuroectodermal tumor (PNET), epithelial tissue and neoplastic mesenchyme.

Around 200 cases of CNS AT/RT have been documented in the literature.

Although the clinical and pathological findings have been defined in large series previously, and AT/RT has become increasingly recognized, awareness of typical AT/RT is important in making the correct diagnosis of this uncommon but probably underdiagnosed entity.

Neuroradiologists rarely mention AT/RT in their differential diagnosis and this paper presents two additional cases in which clinical and pathological findings are combined with neuroradiological presentation.

[MeSH-major] Brain Neoplasms / pathology. Magnetic Resonance Imaging. Rhabdoid Tumor / pathology. Teratoma / pathology

[MeSH-minor] Child. Diagnosis, Differential. Fatal Outcome. Female. Humans. Infant. Male. Tomography, X-Ray Computed

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

MedlinePlus Health Information. consumer health - MRI Scans.

The Lens. Cited by Patents in .

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 18382974.001).

[ISSN] 1019-5149

[Journal-full-title] Turkish neurosurgery

[ISO-abbreviation] Turk Neurosurg

[Language] eng

[Publication-type] Case Reports; Journal Article; Review

[Publication-country] Turkey

[Number-of-references] 18

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Mouse models of CNS embryonal tumors.

Central nervous system (CNS) embryonal tumors are devastating cancers in children, consisting of medulloblastomas, CNS primitive neuroectodermal tumors, and atypical teratoid/rhabdoid tumors.

One of the reasons that CNS embryonal tumors remain difficult to treat is their rarity, which makes conducting clinical trials for these tumors difficult.

Based on the genetic alterations found in humans, multiple models of human CNS embryonal tumors have been generated in genetically engineered mice.

These mouse models are valuable tools for understanding brain tumor biology and discovering novel therapeutic targets and drugs.

In this article, we review molecular and cytogenetic characteristics of human CNS embryonal tumors and corresponding mouse models that have been developed.

These findings indicate that common genetic abnormalities are seen in variants of human CNS embryonal tumors, and multiple histological variants of these tumors can be generated from a single set of genetic abnormalities in mice.

These data provide insight into the biology and classification of CNS embryonal tumors.

[MeSH-major] Central Nervous System Neoplasms / genetics. Disease Models, Animal. Neoplasms, Germ Cell and Embryonal / genetics

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 19856214.001).

[ISSN] 1861-387X

[Journal-full-title] Brain tumor pathology

[ISO-abbreviation] Brain Tumor Pathol

[Language] eng

[Grant] United States / NCI NIH HHS / CA / U01 CA141502

[Publication-type] Journal Article; Review

[Publication-country] Japan

[Number-of-references] 109

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Primary intracranial atypical teratoid/rhabdoid tumors of infancy and childhood: MRI features and patient outcomes.

BACKGROUND AND PURPOSE: Primary atypical teratoid/rhabdoid tumors (AT/RTs) are rare malignant intracranial neoplasms, usually occurring in young children.

The objectives of this study were to characterize the MR imaging features and locations of primary intracranial AT/RTs, to determine the frequency of disseminated disease in the central nervous system (CNS) at diagnosis and postoperatively, and to assess patient outcomes.

METHODS: The preoperative cranial MR images of 13 patients with AT/RTs were retrospectively reviewed for evaluation of lesion location, size, MR signal intensity and enhancement characteristics, and the presence of disseminated intracranial tumor.

Postoperative MR images of the head and spine for 17 patients were reviewed for the presence of locally recurrent or residual tumor and disseminated neoplasm.

A germ-line mutation of the hSNF5/INI1 tumor-suppressor gene was responsible for the simultaneous occurrence of an intracranial AT/RT and a malignant renal rhabdoid tumor in a 4-month-old patient.

Mean tumor sizes were 3.6 x 3.8 x 3.9 cm.

The fraction of tumor volume showing enhancement was greater than two thirds in 58%, between one third and two thirds in 33%, and less than one third in 9%.

Disseminated tumor in the leptomeninges was seen with MR imaging in 24% of patients at diagnosis/initial staging and occurred in another 35% from 4 months to 2.8 years (mean, 1.1 years) after surgery and earlier imaging examinations with negative findings.

Patients with MR imaging evidence of disseminated leptomeningeal tumor had a median survival rate of 16 months compared with 149 months for those without disseminated tumor (P < .004, logrank test).

Poor prognosis is associated with MR imaging evidence of disseminated leptomeningeal tumor.

[MeSH-major] Brain Neoplasms / diagnosis. Magnetic Resonance Imaging. Rhabdoid Tumor / diagnosis. Teratoma / diagnosis

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

MedlinePlus Health Information. consumer health - MRI Scans.

COS Scholar Universe. author profiles.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 16687525.001).

[ISSN] 0195-6108

[Journal-full-title] AJNR. American journal of neuroradiology

[ISO-abbreviation] AJNR Am J Neuroradiol

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid/rhabdoid tumors of the central nervous system: management and outcomes.

OBJECT: Atypical teratoid/rhabdoid tumors (ATRTs) represent a relatively newly categorized neoplastic entity.

Signs and symptoms began, on average, a little more than 1 month before diagnosis and included the following: headache (36%), nausea and vomiting (46%), lethargy (18%), seizures (27%), cranial nerve findings (46%), ataxia (18%), long tract findings (18%), and hydrocephalus (46%).

Tumor location was cortical in four patients, in the pineal region in four, in the posterior fossa in two, and spinal in one.

In one patient disseminated disease was revealed on the initial imaging study; seven patients had disseminated tumor subsequently.

CONCLUSIONS: Atypical teratoid/rhabdoid tumors are malignant lesions with rapid progression.

[MeSH-major] Central Nervous System Neoplasms / therapy. Rhabdoid Tumor / therapy. Teratoma / therapy

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 16048294.001).

[ISSN] 1092-0684

[Journal-full-title] Neurosurgical focus

[ISO-abbreviation] Neurosurg Focus

[Language] eng

[Publication-type] Comparative Study; Journal Article

[Publication-country] United States

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Central nervous system atypical teratoid rhabdoid tumor: experience at the National Institute of Pediatrics, Mexico City.

OBJECTIVE: The purpose of this study is to present our experience with ten cases of Central nervous system atypical teratoid rhabdoid tumor (CNS/ATRT).

PATIENTS AND METHODS: A series of ten patients with CNS/ATRT, were diagnosed and treated between 1990 and 2005, at the National Institute of Pediatrics, in Mexico City.

The gender, age of presentation, clinical features, tumor localization, imaging studies, grade of tumor resection, complications, adjuvant therapy, and survival are presented.

RESULTS: The mean age at diagnosis was 37.8 months, seven cases were male, and their average clinical course was 1.3 months.

CONCLUSIONS: Preliminary results, show that in older children, we can improve their survival with the subtotal or total resection of the tumor and the addition of chemotherapy and radiotherapy.

[MeSH-major] Central Nervous System Neoplasms / pathology. Infratentorial Neoplasms / pathology. Rhabdoid Tumor / pathology. Supratentorial Neoplasms / pathology. Teratoma / pathology

Genetic Alliance. consumer health - Rhabdoid tumor.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Surg Neurol. 1992 May;37(5):410-4 [1631771.001]

[Cites] Childs Nerv Syst. 1997 Jul;13(7):418-21 [9298280.001]

[Cites] Rev Neurol. 2001 Apr 1-15;32(7):618-24 [11391487.001]

[Cites] Pediatr Neurosurg. 1995;22(4):204-9 [7619721.001]

[Cites] J Neurosurg. 1990 Nov;73(5):710-4 [2213160.001]

[Cites] Surg Neurol. 1993 Nov;40(5):429-34 [8211663.001]

[Cites] Pediatr Hematol Oncol. 2003 Jun;20(4):327-32 [12746165.001]

[Cites] AJNR Am J Neuroradiol. 1995 Sep;16(8):1727-8 [7502982.001]

[Cites] J Clin Oncol. 2005 Mar 1;23(7):1491-9 [15735125.001]

[Cites] J Neurosurg. 1996 Jul;85(1):56-65 [8683283.001]

[Cites] J Neurooncol. 2005 Mar;72(1):77-84 [15803379.001]

[Cites] J Pediatr Hematol Oncol. 1995 Feb;17(1):71-5 [7743242.001]

[Cites] Indian J Pediatr. 2005 Aug;72(8):693-6 [16131776.001]

[Cites] Pediatr Neurosurg. 1994;21(4):232-6 [7865408.001]

[Cites] Hum Pathol. 1987 Apr;18(4):332-7 [3030922.001]

(PMID = 17876589.001).

[ISSN] 0256-7040

[Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

[ISO-abbreviation] Childs Nerv Syst

[Language] eng

[Publication-type] Journal Article

[Publication-country] Germany

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Novel role for insulin as an autocrine growth factor for malignant brain tumour cells.

AT/RTs (atypical teratoid/rhabdoid tumours) of the CNS (central nervous system) are childhood malignancies associated with poor survival rates due to resistance to conventional treatments such as chemotherapy.

We characterized a panel of human AT/RT and MRT (malignant rhabdoid tumour) cell lines for expression of RTKs (receptor tyrosine kinases) and their involvement in tumour growth and survival.

Taken together, our results reveal a novel role for autocrine signalling by insulin and the IR in growth and survival of malignant human CNS tumour cells via the PI3K/Akt pathway.

[MeSH-minor] Cell Line, Tumor. Cell Proliferation / drug effects. Child, Preschool. Chromosomal Proteins, Non-Histone / metabolism. Culture Media, Serum-Free. DNA-Binding Proteins / metabolism. Down-Regulation / drug effects. Down-Regulation / genetics. Enzyme Activation / drug effects. Female. Humans. Infant. Isoenzymes / metabolism. Male. Phosphatidylinositol 3-Kinases / metabolism. Proto-Oncogene Proteins c-akt / metabolism. RNA, Small Interfering / metabolism. Receptor, IGF Type 1 / metabolism. Receptor, Insulin / genetics. Receptor, Insulin / metabolism. Signal Transduction / drug effects. Transcription Factors / metabolism

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

MedlinePlus Health Information. consumer health - Diabetes Medicines.

COS Scholar Universe. author profiles.

NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Mol Cell Biol. 2006 Apr;26(7):2661-74 [16537910.001]

[Cites] Cancer Res. 2005 Nov 15;65(22):10123-7 [16287993.001]

[Cites] Cell. 2006 May 19;125(4):733-47 [16647110.001]

[Cites] Biosci Rep. 2006 Feb;26(1):7-17 [16779663.001]

[Cites] J Clin Invest. 2006 Jul;116(7):1761-6 [16823473.001]

[Cites] Drug News Perspect. 2006 Jun;19(5):261-72 [16941048.001]

[Cites] Science. 2006 Oct 13;314(5797):268-74 [16959974.001]

[Cites] Int J Cancer. 2006 Dec 1;119(11):2527-38 [16988940.001]

[Cites] Oncogene. 2007 Apr 5;26(16):2308-17 [17016438.001]

[Cites] Eur J Cancer. 2007 Jul;43(10):1581-9 [17446062.001]

[Cites] Annu Rev Cell Dev Biol. 2001;17:615-75 [11687500.001]

[Cites] Annu Rev Biochem. 2001;70:247-79 [11395408.001]

[Cites] Annu Rev Biochem. 2001;70:535-602 [11395417.001]

[Cites] Nature. 2002 Jan 24;415(6870):436-42 [11807556.001]

[Cites] Mol Cell Biol. 2002 Aug;22(16):5975-88 [12138206.001]

[Cites] Clin Cancer Res. 2002 Nov;8(11):3461-7 [12429635.001]

[Cites] J Immunol. 2003 Mar 1;170(5):2647-54 [12594293.001]

[Cites] Oncogene. 2003 Sep 29;22(42):6589-97 [14528284.001]

[Cites] Horm Metab Res. 2003 Nov-Dec;35(11-12):778-85 [14710358.001]

[Cites] Nat Rev Cancer. 2004 Feb;4(2):133-42 [14964309.001]

[Cites] Nature. 2004 Mar 25;428(6981):427-31 [15042091.001]

[Cites] Cancer Cell. 2004 Mar;5(3):231-9 [15050915.001]

[Cites] Am J Surg Pathol. 2004 May;28(5):644-50 [15105654.001]

[Cites] Science. 2004 Apr 23;304(5670):554 [15016963.001]

[Cites] Nat Rev Cancer. 2004 Jul;4(7):505-18 [15229476.001]

[Cites] J Clin Oncol. 2004 Jul 15;22(14):2877-84 [15254056.001]

[Cites] Cancer Res. 2004 Aug 1;64(15):5048-50 [15289301.001]

[Cites] Clin Cancer Res. 2004 Sep 1;10(17):5940-8 [15355927.001]

[Cites] Biochem J. 1990 Sep 1;270(2):397-400 [2205203.001]

[Cites] J Biol Chem. 1992 Jul 5;267(19):13488-97 [1618850.001]

[Cites] Annu Rev Biochem. 1992;61:307-30 [1323236.001]

[Cites] EMBO J. 1993 Nov;12(11):4251-9 [7901001.001]

[Cites] Endocrinology. 1995 Apr;136(4):1459-67 [7534700.001]

[Cites] Endocr Rev. 1995 Feb;16(1):3-34 [7758431.001]

[Cites] Genes Dev. 1996 Sep 1;10(17):2117-30 [8804307.001]

[Cites] EMBO J. 1996 Oct 1;15(19):5370-82 [8895581.001]

[Cites] Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3777-82 [9108054.001]

[Cites] Trends Biochem Sci. 1997 Jul;22(7):267-72 [9255069.001]

[Cites] Nature. 1998 Jul 9;394(6689):203-6 [9671307.001]

[Cites] Cancer Res. 1999 Jan 1;59(1):74-9 [9892189.001]

[Cites] Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4240-5 [10200246.001]

[Cites] Hum Mol Genet. 1999 Dec;8(13):2359-68 [10556283.001]

[Cites] Clin Cancer Res. 2000 Jul;6(7):2759-63 [10914721.001]

[Cites] Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13796-800 [11095756.001]

[Cites] Pediatr Dev Pathol. 2001 Jan-Feb;4(1):23-31 [11200487.001]

[Cites] Mol Cell Biol. 2001 May;21(10):3598-603 [11313485.001]

[Cites] J Neurooncol. 2005 Dec;75(3):309-13 [16195799.001]

[Cites] Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17745-50 [16301525.001]

[Cites] Oncogene. 2006 Feb 2;25(5):722-34 [16302003.001]

[Cites] Oncogene. 2006 Feb 16;25(7):1111-7 [16186793.001]

[Cites] Br J Cancer. 2006 Feb 27;94(4):465-8 [16450000.001]

[Cites] Mol Cell Biol. 1999 May;19(5):3278-88 [10207053.001]

[Cites] Oncogene. 1999 Apr 15;18(15):2471-9 [10229198.001]

[Cites] Mod Pathol. 1999 Apr;12(4):379-85 [10229502.001]

[Cites] Endocrinology. 2005 Feb;146(2):552-7 [15550513.001]

[Cites] J Pathol. 2005 Jan;205(2):145-53 [15641016.001]

[Cites] J Clin Oncol. 2005 Mar 1;23(7):1491-9 [15735125.001]

[Cites] Nat Med. 2005 May;11(5):507-14 [15834429.001]

[Cites] Cytokine Growth Factor Rev. 2005 Aug-Oct;16(4-5):421-39 [15936977.001]

[Cites] Blood. 2005 Aug 15;106(4):1432-40 [15878979.001]

[Cites] Nature. 2006 May 18;441(7091):366-70 [16625210.001]

(PMID = 17506723.001).

[ISSN] 1470-8728

[Journal-full-title] The Biochemical journal

[ISO-abbreviation] Biochem. J.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / Chromosomal Proteins, Non-Histone; 0 / Culture Media, Serum-Free; 0 / DNA-Binding Proteins; 0 / Growth Substances; 0 / Insulin; 0 / Isoenzymes; 0 / RNA, Small Interfering; 0 / SMARCB1 protein, human; 0 / Transcription Factors; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.10.1 / Receptor, IGF Type 1; EC 2.7.10.1 / Receptor, Insulin; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt

[Other-IDs] NLM/ PMC1948991

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Primary intracranial extra-axial and supratentorial atypical rhabdoid tumor.

An atypical teratoid/rhabdoid tumor of the central nervous system is an aggressive infantile embryonal neoplasm, usually presenting as an infratentorial and intraparenchymatous lesion.

We report on magnetic resonance imaging findings of a 22-month-old boy with a biopsy-proven primary rhabdoid tumor, presenting as a single intracranial supratentorial extra-axial mass.

Based on the patient's age and imaging features (perfusion, diffusion magnetic resonance imaging, and magnetic resonance spectroscopy), a diagnosis of atypical teratoid/rhabdoid tumor was more accurate than diagnoses of meningioma and primitive neuroectodermal tumor.

Although this entity is relatively rare, it should be considered in the differential diagnosis of dural-based, space-occupying central nervous system lesions.

[MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / pathology. Rhabdoid Tumor / diagnosis. Rhabdoid Tumor / pathology. Supratentorial Neoplasms / diagnosis. Supratentorial Neoplasms / pathology

[MeSH-minor] Brain / metabolism. Brain / pathology. Brain / surgery. Brain Edema / pathology. Diagnosis, Differential. Diffusion Magnetic Resonance Imaging. Humans. Infant. Magnetic Resonance Imaging. Magnetic Resonance Spectroscopy. Male. Neoplasm Recurrence, Local. Treatment Outcome

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Brain Tumors.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 19931170.001).

[ISSN] 1873-5150

[Journal-full-title] Pediatric neurology

[ISO-abbreviation] Pediatr. Neurol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Our aim is to evaluate the clinical features and outcomes of children with primary central nervous system (CNS) tumors who develop extraneural metastasis (ENM).

We retrospectively evaluated children diagnosed with primary CNS tumors treated at our institution between 1972 and 2004.

The histopathologic diagnosis was medulloblastoma in six patients, germ cell tumors in two patients, and ependymoma and atypical teratoid rhabdoid tumor (ATRT) in one patient each.

In six patients, the primary tumor was located in the posterior fossa; it had a supratentorial location in the patient with ATRT, was located in the sellar and suprasellar region in the two patients with germ cell tumors, and was found in the distal spinal cord in the patient with an ependymoma.

In two patients ENM was detected at the time of diagnosis.

In other patients ENM developed between 9 and 25 months after diagnosis.

One patient with dysgerminoma is alive, without disease, 117.80 months after diagnosis of the ENM.

One patient with germ cell tumor is alive with disease 11.3 months after diagnosis of the ENM.

The outcome is poor in patients with CNS tumors with ENM.

[MeSH-major] Central Nervous System Neoplasms / pathology. Liver Neoplasms / secondary. Lung Neoplasms / secondary. Medulloblastoma / secondary. Neoplasms, Germ Cell and Embryonal / pathology

[MeSH-minor] Adolescent. Bone Marrow Neoplasms / mortality. Bone Marrow Neoplasms / secondary. Bone Neoplasms / mortality. Bone Neoplasms / secondary. Child. Child, Preschool. Ependymoma / mortality. Ependymoma / secondary. Female. Humans. Male. Neoplasm Metastasis. Prognosis. Retrospective Studies. Rhabdoid Tumor / mortality. Rhabdoid Tumor / secondary. Teratoma / mortality. Teratoma / secondary

MedlinePlus Health Information. consumer health - Liver Cancer.

MedlinePlus Health Information. consumer health - Lung Cancer.

COS Scholar Universe. author profiles.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Neuroradiology. 1979 Apr 26;17 (4):219-22 [450247.001]

[Cites] J Neurooncol. 1988;6(1):53-9 [3294352.001]

[Cites] Ann Neurol. 1981 Sep;10(3):261-5 [7294733.001]

[Cites] Acta Neurochir (Wien). 1996;138(10):1172-7; discussion 1177-8 [8955436.001]

[Cites] Neurology. 1989 Dec;39(12):1593-6 [2685656.001]

[Cites] Radiology. 1973 May;107(2):359-62 [4695903.001]

[Cites] J Pediatr Hematol Oncol. 2003 Mar;25(3):198-203 [12621237.001]

[Cites] Eur J Pediatr. 1977 Jan 26;124(2):155-64 [188658.001]

[Cites] J Neurooncol. 2001 Aug;54(1):53-6 [11763423.001]

[Cites] Neurol Med Chir (Tokyo). 2004 Dec;44(12):669-73 [15684601.001]

[Cites] Cancer Treat Rep. 1984 Oct;68(10):1307-9 [6543153.001]

[Cites] Ann Neurol. 1984 Jul;16(1):94-5 [6465867.001]

[Cites] Cancer. 2003 Nov 15;98(10):2232-44 [14601094.001]

[Cites] Cancer. 1981 Jul 1;48(1):213-6 [7237388.001]

[Cites] Pathol Int. 1999 Mar;49(3):258-63 [10338084.001]

[Cites] Clin Orthop Relat Res. 1989 Oct;(247):256-60 [2676297.001]

[Cites] Med Pediatr Oncol. 1999 Aug;33(2):126-8 [10398191.001]

[Cites] J Neurooncol. 2004 Feb;66(3):265-71 [15015656.001]

[Cites] Am J Clin Pathol. 1966 Aug;46(2):245-9 [5296530.001]

(PMID = 16645723.001).

[ISSN] 0167-594X

[Journal-full-title] Journal of neuro-oncology

[ISO-abbreviation] J. Neurooncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid or rhabdoid tumors: improved outcome with high-dose chemotherapy.

PURPOSE: To retrospectively review an institutional experience in managing atypical teratoid/rhabdoid tumors (AT/RT) of the Central Nervous System with high-dose chemotherapy in infants and children less than 4 years old.

Tumor location was supratentorial in 3 cases, infratentorial in 3 cases, and multifocal in 2 patients.

RESULTS: At a median follow-up of 52 months, 4 patients are alive without evidence of tumor.

[MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Brain Neoplasms / drug therapy. Rhabdoid Tumor / drug therapy. Teratoma / drug therapy

[MeSH-minor] Child, Preschool. Cisplatin / administration & dosage. Combined Modality Therapy. Cranial Irradiation. Cyclophosphamide / administration & dosage. Etoposide / administration & dosage. Female. Humans. Infant. Male. Neoplasm Metastasis. Radiotherapy Dosage. Retrospective Studies. Survival Rate. Treatment Outcome. Vincristine / administration & dosage

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

Hazardous Substances Data Bank. ETOPOSIDE .

Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .

Hazardous Substances Data Bank. VINCRISTINE .

[Email] Email this result item

Email the results to the following email address:   [X] Close

[ErratumIn] J Pediatr Hematol Oncol. 2011 Jul;33(5):400. Laura, Janzen [corrected to Janzen, Laura]

(PMID = 20495479.001).

[ISSN] 1536-3678

[Journal-full-title] Journal of pediatric hematology/oncology

[ISO-abbreviation] J. Pediatr. Hematol. Oncol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 8N3DW7272P / Cyclophosphamide; Q20Q21Q62J / Cisplatin

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Successful multimodal therapies for a primary atypical teratoid/rhabdoid tumor in the cervical spine.

Atypical teratoid/rhabdoid tumor (AT/RT) occurring in the central nervous system is a high-grade malignant tumor, and its prognosis is poor for patients younger than 3 years of age.

At the age of nearly 3 years, she received radiation therapy to the local tumor bed and craniospinal axis.

The success of this treatment for the patient was that we could prevent tumor recurrence until she was able to receive radiotherapy.

[MeSH-major] Cervical Vertebrae / pathology. Rhabdoid Tumor / drug therapy. Spinal Neoplasms / drug therapy. Teratoma / drug therapy

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Neck Injuries and Disorders.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Copyright] (c) 2008 S. Karger AG, Basel.

(PMID = 18703889.001).

[ISSN] 1423-0305

[Journal-full-title] Pediatric neurosurgery

[ISO-abbreviation] Pediatr Neurosurg

[Language] eng

[Publication-type] Case Reports; Journal Article; Review

[Publication-country] Switzerland

[Chemical-registry-number] 0 / Antineoplastic Agents

[Number-of-references] 22

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid/rhabdoid tumors (ATRT): improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy.

PURPOSE: To describe clinical features, therapeutic approaches, and prognostic factors in pediatric patients with atypical teratoid/rhabdoid tumors (ATRT) treated at St Jude Children's Research Hospital (SJCRH).

PATIENTS AND METHODS: Primary tumor samples from patients diagnosed with ATRT at SJCRH between July 1984 and June 2003 were identified.

Posterior fossa primary lesions and metastatic disease at diagnosis were more common in younger patients with ATRT.

[MeSH-major] Central Nervous System Neoplasms / therapy. Neoplasms, Germ Cell and Embryonal / therapy. Rhabdoid Tumor / therapy. Teratoma / therapy

COS Scholar Universe. author profiles.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 15735125.001).

[ISSN] 0732-183X

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Grant] United States / NCI NIH HHS / CA / CA 21765

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

[Publication-country] United States

[Chemical-registry-number] 0 / SMARCC1 protein, human; 0 / Transcription Factors

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid/rhabdoid tumor mimicking tuberculous meningitis.

Atypical teratoid/rhabdoid tumor of the central nervous system is a highly malignant neoplasm in infants and young children.

We report a 6 year-old girl with atypical teratoid/rhabdoid tumor.

Pathologic result revealed high grade atypical teratoid/rhabdoid tumor.

[MeSH-major] Rhabdoid Tumor / diagnosis. Teratoma / diagnosis. Tuberculosis, Meningeal / diagnosis

[MeSH-minor] Cerebrospinal Fluid. Child. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging

Genetic Alliance. consumer health - Rhabdoid tumor.

Genetic Alliance. consumer health - Tuberculous meningitis.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 18451456.001).

[ISSN] 0019-6061

[Journal-full-title] Indian pediatrics

[ISO-abbreviation] Indian Pediatr

[Language] eng

[Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] India

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Neuroradiological findings in atypical teratoid/rhabdoid tumor of the central nervous system.

PURPOSE: To evaluate the computed tomography (CT) and magnetic resonance imaging (MRI) findings of atypical teratoid tumor/rhabdoid tumor (AT/RT) of the central nervous system (CNS).

MATERIAL AND METHODS: Twenty cases of CNS AT/RT have been found over the past 23 years in our hospital; these involving 11 boys and 9 girls whose mean age at diagnosis was 5.5 years.

The diagnosis mainly depends on the pathologic findings.

However, AT/RT should still remain in the differential diagnosis of brain tumors in young children, especially those located in the cerebellar hemisphere and with eccentric cysts.

[MeSH-major] Central Nervous System Neoplasms / pathology. Central Nervous System Neoplasms / radiography. Rhabdoid Tumor / pathology. Rhabdoid Tumor / radiography. Teratoma / pathology. Teratoma / radiography

[MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Infant. Magnetic Resonance Imaging. Male. Prognosis. Retrospective Studies. Survival Rate. Tomography, X-Ray Computed

Genetic Alliance. consumer health - Rhabdoid tumor.

NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 15841745.001).

[ISSN] 0284-1851

[Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)

[ISO-abbreviation] Acta Radiol

[Language] eng

[Publication-type] Journal Article

[Publication-country] Sweden

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Embryonal tumor with abundant neuropil and true rosettes (ETANTR): a new distinctive variety of pediatric PNET: a case-based update.

BACKGROUND: Embryonal central nervous system (CNS) tumors are currently classified into three types: medulloblastoma, atypical rhabdoid/teratoid tumors, and primitive neuroectodermal tumor (PNET).

A distinctive subtype of PNET called "embryonal tumor with abundant neuropil and true rosettes" (ETANTR) was reported in 2000.

It has been suggested that this neoplasm should be considered as a separate entity.

ETANTR is an eminently pediatric tumor that has been reported exclusively in children younger than 4 years.

ILLUSTRATIVE CASES: A 9-month-old girl underwent subtotal resection of a brainstem neoplasm.

A 23-month-old girl was submitted to surgery for a frontoparietal tumor.

In both instances, the histopathological diagnosis confirmed ETANTR.

CONCLUSIONS: By reporting these two new instances of ETANTR, we want to contribute to the knowledge of this highly malignant CNS embryonal neoplasm that occurs only in young children, given its present lethal prognosis, the scarcity of reported cases, and the lack of treatment guidelines.

MedlinePlus Health Information. consumer health - Brain Tumors.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Am J Surg Pathol. 2009 Feb;33(2):211-7 [18987548.001]

[Cites] Acta Neuropathol. 2009 Apr;117(4):457-64 [19057917.001]

[Cites] J Neurooncol. 2007 Aug;84(1):91-8 [17332950.001]

[Cites] Brain Pathol. 2010 Jan;20(1):133-9 [19120373.001]

[Cites] Acta Neuropathol. 2007 Aug;114(2):97-109 [17618441.001]

[Cites] Pediatr Dev Pathol. 2000 Jul-Aug;3(4):346-52 [10890250.001]

[Cites] Brain Pathol. 2009 Apr;19(2):343-6 [19291003.001]

[Cites] Neuropathology. 2010 Feb 1;30(1):84-91 [19563506.001]

[Cites] N Engl J Med. 2005 Mar 10;352(10):978-86 [15758008.001]

[Cites] J Neurooncol. 2006 Jul;78(3):317-20 [16598427.001]

[Cites] Am J Clin Pathol. 2006 Aug;126(2):277-83 [16891204.001]

(PMID = 20499240.001).

[ISSN] 1433-0350

[Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

[ISO-abbreviation] Childs Nerv Syst

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

[Chemical-registry-number] 0 / Antineoplastic Agents

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Immunohistochemistry of INI1 expression: a new tool for old challenges in CNS and soft tissue pathology.

Loss of expression of INI1 as detected by immunohistochemical staining correlates with deletion and mutations of the INI1 gene in patients with malignant rhabdoid tumors and central nervous system atypical teratoid/rhabdoid tumors and as such is a sensitive and specific marker for these tumors.

Loss of INI1 expression may rarely be encountered in other tumor types.

[MeSH-major] Biomarkers, Tumor / metabolism. Central Nervous System Neoplasms / diagnosis. Chromosomal Proteins, Non-Histone / metabolism. DNA-Binding Proteins / metabolism. Immunohistochemistry / methods. Soft Tissue Neoplasms / diagnosis. Transcription Factors / metabolism

COS Scholar Universe. author profiles.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 17717433.001).

[ISSN] 1072-4109

[Journal-full-title] Advances in anatomic pathology

[ISO-abbreviation] Adv Anat Pathol

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / SMARCB1 protein, human; 0 / Transcription Factors

[Number-of-references] 20

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Establishment of atypical-teratoid/rhabdoid tumor (AT/RT) cell cultures from disseminated CSF cells: a model to elucidate biology and potential targeted therapeutics.

Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant central nervous system neoplasm that usually affects infants and young children.

In this report, we describe culture conditions that enabled the sustained growth of tumor cells obtained from the cerebrospinal fluid (CSF) of an infant with AT/RT.

These cells retained the morphological and biomarker characteristics of the original tumor.

In addition to previously described cell lines and xenograft models, continuous culture of CSF derived cells may also provide an effective way to study the biology of AT/RT and to identify potential targets for future therapeutics for this tumor.

[MeSH-major] Platelet Aggregation Inhibitors / therapeutic use. Rhabdoid Tumor / cerebrospinal fluid. Rhabdoid Tumor / drug therapy

[MeSH-minor] Actins / metabolism. Cell Proliferation. Chromosomal Proteins, Non-Histone / metabolism. DNA-Binding Proteins / metabolism. Dose-Response Relationship, Drug. Glial Fibrillary Acidic Protein / metabolism. Humans. Infant. Inhibitory Concentration 50. Male. Models, Biological. Nuclear Proteins / metabolism. Receptor Protein-Tyrosine Kinases / metabolism. SMARCB1 Protein. Transcription Factors / metabolism. Tumor Cells, Cultured / pathology. Vimentin / metabolism

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Blood Thinners.

Cellosaurus - a cell line knowledge resource. culture/stock collections - Cellosaurus - a cell line knowledge resource .

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Mol Cell Biol. 2001 May;21(10 ):3598-603 [11313485.001]

[Cites] Eur J Cancer. 2007 Jul;43(10):1581-9 [17446062.001]

[Cites] Pediatr Dev Pathol. 2001 Jan-Feb;4(1):23-31 [11200487.001]

[Cites] Genes Chromosomes Cancer. 2000 May;28(1):31-7 [10738300.001]

[Cites] Pediatr Blood Cancer. 2008 Jul;51(1):42-8 [18293383.001]

[Cites] Handb Exp Pharmacol. 2006;(172):259-77 [16610363.001]

[Cites] Acta Neurochir (Wien). 1997;139(7):619-24 [9265954.001]

[Cites] J Biosci. 2007 Apr;32(3):517-30 [17536171.001]

[Cites] Cancer Res. 2006 Jan 1;66(1):362-71 [16397250.001]

[Cites] Leukemia. 2007 May;21(5):886-96 [17361225.001]

[Cites] Oncogene. 2006 Aug 3;25(33):4605-12 [16568092.001]

[Cites] Cancer Res. 2005 Nov 15;65(22):10123-7 [16287993.001]

[Cites] Nat Med. 2002 Mar;8(3):282-8 [11875500.001]

[Cites] Oncogene. 2002 Sep 19;21(42):6403-12 [12226744.001]

[Cites] Comp Biochem Physiol B Biochem Mol Biol. 1998 Sep;121(1):19-26 [9972281.001]

[Cites] Acta Biochim Pol. 2003;50(3):647-58 [14515146.001]

[Cites] Biochem Biophys Res Commun. 2007 Sep 28;361(3):580-5 [17669367.001]

[Cites] Eur J Cancer. 2006 Sep;42(14 ):2326-34 [16908131.001]

[Cites] EMBO Rep. 2000 Dec;1(6):500-6 [11263494.001]

[Cites] Breast Cancer Res. 2005;7(5):R765-74 [16168122.001]

[Cites] Neuropathology. 2002 Dec;22(4):252-60 [12564764.001]

[Cites] Anticancer Res. 1997 Nov-Dec;17(6B):4121-6 [9428345.001]

[Cites] Clin Cancer Res. 2006 Nov 15;12(22):6772-80 [17121898.001]

[Cites] J Cancer Res Clin Oncol. 2007 Nov;133(11):817-24 [17486366.001]

[Cites] Horm Metab Res. 2003 Nov-Dec;35(11-12):843-9 [14710367.001]

[Cites] In Vivo. 2005 Sep-Oct;19(5):931-41 [16097449.001]

[Cites] Br J Cancer. 2006 Feb 27;94(4):465-8 [16450000.001]

[Cites] Biochem Biophys Res Commun. 2007 Nov 16;363(2):241-6 [17826744.001]

[Cites] Cancer Res. 2002 Jan 1;62(1):323-8 [11782395.001]

[Cites] Clin Cancer Res. 2007 Mar 15;13(6):1625-9 [17363512.001]

[Cites] Cancer Res. 2006 May 15;66(10):5085-93 [16707431.001]

[Cites] Am J Pathol. 2005 Apr;166(4):1153-62 [15793295.001]

[Cites] Leuk Res. 2002 Sep;26(9):831-7 [12127559.001]

[Cites] Biochem J. 2007 Aug 15;406(1):57-66 [17506723.001]

[Cites] Cancer Res. 1999 Jan 1;59(1):74-9 [9892189.001]

[Cites] Clin Cancer Res. 2007 Aug 15;13(16):4721-30 [17699849.001]

[Cites] Diagn Cytopathol. 2000 Nov;23(5):329-32 [11074628.001]

[Cites] Int J Radiat Oncol Biol Phys. 2006 Jun 1;65(2):493-8 [16563655.001]

[Cites] Prog Exp Tumor Res. 1987;30:57-60 [2819946.001]

[Cites] Int J Cancer. 2007 Apr 15;120(8):1787-94 [17230517.001]

[Cites] Adv Exp Med Biol. 2003;532:141-51 [12908555.001]

[Cites] Pediatr Res. 2005 Mar;57(3):430-7 [15659698.001]

[Cites] Cancer Cell. 2004 Mar;5(3):231-9 [15050915.001]

[Cites] Adv Cancer Res. 2006;95:323-48 [16860662.001]

[Cites] J Neuropathol Exp Neurol. 2005 May;64(5):391-7 [15892296.001]

[Cites] Endocr Relat Cancer. 2006 Dec;13 Suppl 1:S125-35 [17259553.001]

(PMID = 18651103.001).

[ISSN] 0167-594X

[Journal-full-title] Journal of neuro-oncology

[ISO-abbreviation] J. Neurooncol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Actins; 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / Glial Fibrillary Acidic Protein; 0 / Nuclear Proteins; 0 / Platelet Aggregation Inhibitors; 0 / SMARCB1 Protein; 0 / SMARCB1 protein, human; 0 / Transcription Factors; 0 / Vimentin; EC 2.7.10.1 / Receptor Protein-Tyrosine Kinases

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Elevation of plasma and cerebrospinal fluid osteopontin levels in patients with atypical teratoid/rhabdoid tumor.

Osteopontin, a cancer metastasis-associated gene, is specifically up-regulated in central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT), but its biological behavior in the progression of CNS AT/RT has never been studied.

The differences in osteopontin expression in plasma, CSF, and tumor samples in AT/RT and medulloblastoma correlated with survival differences.

[MeSH-major] Brain Neoplasms / metabolism. Rhabdoid Tumor / metabolism. Sialoglycoproteins. Teratoma / metabolism

[MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Enzyme-Linked Immunosorbent Assay. Humans. Infant. Infant, Newborn. Medulloblastoma / metabolism. Medulloblastoma / mortality. Medulloblastoma / pathology. Neoplasm Recurrence, Local. Osteopontin. Survival Rate

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

COS Scholar Universe. author profiles.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 15842057.001).

[ISSN] 0002-9173

[Journal-full-title] American journal of clinical pathology

[ISO-abbreviation] Am. J. Clin. Pathol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / SPP1 protein, human; 0 / Sialoglycoproteins; 106441-73-0 / Osteopontin

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Carboplatin-based primary chemotherapy for infants and young children with CNS tumors.

BACKGROUND: A carboplatin-based chemotherapy regimen was used as primary postoperative therapy in infants with central nervous system (CNS) tumors to limit renal and ototoxicity and to target systemic exposure.

METHODS: Fifty-three patients aged <age 3 years with embryonal CNS tumor medulloblastoma (n = 20), ependymoma (EP, n = 21), choroid plexus carcinoma (CPCA, n = 5), and primitive embryonal neoplasms including atypical teratoid rhabdoid tumors (n = 7) were treated with cyclophosphamide, etoposide, and carboplatin.

For medulloblastoma, the 5-year PFS was 26% +/- 9%; for EP it was 33% +/- 10%; for CPCA it was 80% +/- 18%; and for primitive neuroectodermal and atypical teratoid rhabdoid tumors it was 0%.

[MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carboplatin / administration & dosage. Central Nervous System Neoplasms / drug therapy

COS Scholar Universe. author profiles.

Hazardous Substances Data Bank. ETOPOSIDE .

Hazardous Substances Data Bank. CARBOPLATIN .

Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .

NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 19484793.001).

[ISSN] 0008-543X

[Journal-full-title] Cancer

[ISO-abbreviation] Cancer

[Language] eng

[Grant] United States / NCI NIH HHS / CA / P30 CA021765; United States / NCI NIH HHS / CA / P30 CA021765-30; United States / NCI NIH HHS / CA / R25 CA023944; United States / NCI NIH HHS / CA / CA21765

[Publication-type] Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 6PLQ3CP4P3 / Etoposide; 8N3DW7272P / Cyclophosphamide; BG3F62OND5 / Carboplatin

[Other-IDs] NLM/ NIHMS124374; NLM/ PMC4307774

   

[Fulltext service] Download fulltext PDF of this article and others, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Current treatment approaches for infants with malignant central nervous system tumors.

Nearly three decades of infant brain tumor clinical trials have led to significant progress in the delineation of prognostic factors and improvements in outcome.

This review covers the most recent therapeutic advances for the most common histological subtypes of malignant infant brain tumors: medulloblastoma, supratentorial primitive neuroectodermal tumor, ependymoma, atypical teratoid rhabdoid tumor, choroid plexus carcinoma, and high-grade glioma.

[MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma / therapy. Cerebellar Neoplasms / therapy. Chemotherapy, Adjuvant. Choroid Plexus Neoplasms / therapy. Clinical Trials as Topic. Clinical Trials, Phase III as Topic. Ependymoma / therapy. Evidence-Based Medicine. Glioma / therapy. Humans. Infant. Medulloblastoma / therapy. Meta-Analysis as Topic. Neuroectodermal Tumors, Primitive / therapy. Prognosis. Radiotherapy Dosage. Radiotherapy, Adjuvant. Rhabdoid Tumor / therapy. Stem Cell Transplantation. Supratentorial Neoplasms / therapy

MedlinePlus Health Information. consumer health - Brain Tumors.

[Email] Email this result item

Email the results to the following email address:   [X] Close

(PMID = 19342475.001).

[ISSN] 1549-490X

[Journal-full-title] The oncologist

[ISO-abbreviation] Oncologist

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] United States

[Number-of-references] 116

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid rhabdoid tumor (AT/RT) in adults: review of four cases.

Atypical teratoid/rhabdoid (AT/RT) tumor is a rare, highly malignant tumor of the central nervous system (CNS) most commonly found in children less than 5 years of age.

In many instances, a reliable diagnosis is not possible without demonstrating the lack of nuclear INI1 protein expression by immunohistochemical methods.

In all cases, diagnosis during intraoperative consultation and preliminary diagnosis was different from the final diagnosis after immunohistochemical analysis.

Immunohistochemical staining showed that the tumor cells were positive for vimentin and reacted variably for keratin, epithelial membrane antigen (EMA), synaptophysin, neurofilament protein, CD34, and smooth muscle actin (SMA).

One patient is alive with no evidence of disease 17 years after the diagnosis.

In adult examples of AT/RT, the diagnosis requires a high index of suspicion, with early tissue diagnosis and a low threshold for investigation with INI1 immunohistochemistry to differentiate this entity from other morphologically similar tumors.

[MeSH-major] Brain Neoplasms / metabolism. Brain Neoplasms / pathology. Rhabdoid Tumor / metabolism. Rhabdoid Tumor / pathology

[MeSH-minor] Adult. Chromosomal Proteins, Non-Histone / metabolism. DNA-Binding Proteins / metabolism. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. SMARCB1 Protein. Transcription Factors / metabolism

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Brain Tumors.

NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Hum Pathol. 1981 Jul;12(7):646-57 [7275104.001]

[Cites] Semin Cell Dev Biol. 1999 Apr;10 (2):189-95 [10441072.001]

[Cites] J Neurooncol. 2001 Mar;52(1):49-56 [11451202.001]

[Cites] J Neurooncol. 2003 Jan;61(2):121-6 [12622450.001]

[Cites] Mod Pathol. 2005 Jul;18(7):951-8 [15761491.001]

[Cites] Genes Dev. 1998 Aug 1;12(15):2278-92 [9694794.001]

[Cites] Am J Surg Pathol. 1993 Jul;17(7):729-37 [8391222.001]

[Cites] J Clin Oncol. 2004 Jul 15;22(14):2877-84 [15254056.001]

[Cites] Neuro Oncol. 2006 Jan;8(1):79-82 [16443951.001]

[Cites] Can J Neurol Sci. 1996 Nov;23(4):257-63 [8951203.001]

[Cites] Neuroradiology. 2000 May;42(5):363-7 [10872158.001]

[Cites] Pathol Int. 1999 Dec;49(12):1114-8 [10632935.001]

[Cites] Clin Cancer Res. 2002 Nov;8(11):3461-7 [12429635.001]

[Cites] Acta Neuropathol. 1992;83(4):445-8 [1575023.001]

[Cites] J Neurooncol. 2005 Sep;74(3):311-9 [16132523.001]

[Cites] J Pediatr Hematol Oncol. 2002 Jun-Jul;24(5):337-42 [12142780.001]

[Cites] Am J Surg Pathol. 1994 Oct;18(10):1010-29 [8092393.001]

[Cites] Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12311-5 [10535918.001]

[Cites] Cancer Res. 2000 Nov 1;60(21):6171-7 [11085541.001]

[Cites] Med Pediatr Oncol. 1997 Mar;28(3):223-7 [9024522.001]

[Cites] Brain Pathol. 2005 Jan;15(1):23-8 [15779233.001]

[Cites] J Neurosurg. 1996 Jul;85(1):56-65 [8683283.001]

[Cites] Acta Neurochir (Wien). 2004 Sep;146(9):1033-8; discussion 1038 [15340816.001]

[Cites] Int J Radiat Oncol Biol Phys. 1999 Aug 1;45(1):247 [10477033.001]

[Cites] Neuropathology. 2002 Dec;22(4):252-60 [12564764.001]

[Cites] Am J Surg Pathol. 2004 May;28(5):644-50 [15105654.001]

[Cites] Pediatr Radiol. 2006 Feb;36(2):126-32 [16341528.001]

[Cites] Cancer Res. 2002 Jan 1;62(1):323-8 [11782395.001]

[Cites] Cancer. 1978 May;41(5):1937-48 [206343.001]

[Cites] Hum Pathol. 2001 Feb;32(2):156-62 [11230702.001]

[Cites] Cancer Res. 2004 May 15;64(10 ):3406-13 [15150092.001]

[Cites] Neuropathology. 2006 Feb;26(1):57-61 [16521480.001]

[Cites] J Neurooncol. 2007 Aug;84(1):49-55 [17377740.001]

[Cites] Cancer Res. 1999 Jan 1;59(1):74-9 [9892189.001]

[Cites] Neurol India. 2003 Jun;51(2):273-4 [14571026.001]

[Cites] Ultrastruct Pathol. 1997 Jul-Aug;21(4):361-8 [9206001.001]

[Cites] Science. 1994 Dec 23;266(5193):2002-6 [7801128.001]

[Cites] Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7748-53 [10884406.001]

[Cites] Mol Cell. 1999 Feb;3(2):247-53 [10078207.001]

(PMID = 18369529.001).

[ISSN] 0167-594X

[Journal-full-title] Journal of neuro-oncology

[ISO-abbreviation] J. Neurooncol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / SMARCB1 Protein; 0 / SMARCB1 protein, human; 0 / Transcription Factors

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [The role of diagnostic neuropathology in familial tumour syndromes].

Inherited cancer syndromes often involve the central and peripheral nervous system.

For the surgical neuropathologist the possibility in individual patients of a familial tumour syndrome needs to be considered in the case of special tumours such as malignant peripheral nerve sheath tumour (MPNST), medulloblastoma with extensive nodularity (MBEN) or even atypical teratoid/rhabdoid tumour (AT/RT) of the brain.

Furthermore, tumour location and patient age may point to a familial tumour syndrome as in the case of neurofibromatosis type 2 (NF2) with typical bilateral vestibular schwannoma in young age.

[MeSH-minor] Central Nervous System Neoplasms / genetics. Central Nervous System Neoplasms / pathology. Chromosome Mapping. Chromosomes, Human, Pair 16. Chromosomes, Human, Pair 17. Chromosomes, Human, Pair 22. Chromosomes, Human, Pair 9. Genes, Neurofibromatosis 1. Genes, Neurofibromatosis 2. Humans. Li-Fraumeni Syndrome / genetics. Li-Fraumeni Syndrome / pathology. Neurofibromatosis 1 / genetics. Neurofibromatosis 1 / pathology. Neurofibromatosis 2 / genetics. Neurofibromatosis 2 / pathology. Neuroma, Acoustic / genetics. Neuroma, Acoustic / pathology. Peripheral Nervous System Neoplasms / genetics. Peripheral Nervous System Neoplasms / pathology. Rhabdoid Tumor / genetics. Rhabdoid Tumor / pathology. Teratoma / genetics. Teratoma / pathology. Tuberous Sclerosis / genetics. Tuberous Sclerosis / pathology

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Genet Med. 2010 Jan;12(1):1-11 [20027112.001]

[Cites] Genet Med. 2009 Sep;11(9):599-610 [19652604.001]

[Cites] Clin Cancer Res. 2009 Apr 1;15(7):2463-71 [19276247.001]

[Cites] Acta Neuropathol. 2007 Aug;114(2):97-109 [17618441.001]

[Cites] J Neurosurg. 1999 Dec;91(6):971-7 [10584843.001]

(PMID = 20848106.001).

[ISSN] 1432-1963

[Journal-full-title] Der Pathologe

[ISO-abbreviation] Pathologe

[Language] ger

[Publication-type] English Abstract; Journal Article; Review

[Publication-country] Germany

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Atypical teratoid/rhabdoid tumor of the central nervous system: clinicopathologic and immunohistochemical features of four cases.

BACKGROUND: Atypical teratoid/rhabdoid tumor (AT/RT) is a rare aggressive infantile neoplasm of uncertain origin.

Histopathologically, the tumors were composed of rhabdoid cells and undifferentiated small cells mixed with epithelial or mesenchymal components.

All of the patients died within a mean of 14 months due to tumor progression despite the chemotherapy.

Only one of our patients lived for 40 months after the diagnosis.

Morphologically, a large spectrum can be seen, like predominantly sarcoma in appearance, but immunohistochemistry is helpful in the correct diagnosis.

[MeSH-major] Brain Neoplasms / pathology. Rhabdoid Tumor / pathology. Teratoma / pathology

[MeSH-minor] Actins / analysis. Brain / pathology. Brain Chemistry. Child. Child, Preschool. Chromosomal Proteins, Non-Histone / analysis. DNA-Binding Proteins / analysis. Desmin / analysis. Diagnosis, Differential. Female. Glial Fibrillary Acidic Protein / analysis. Humans. Immunohistochemistry. Infant. Keratins / analysis. Male. Mucin-1 / analysis. S100 Proteins / analysis. SMARCB1 Protein. Synaptophysin / analysis. Transcription Factors / analysis. Vimentin / analysis

Genetic Alliance. consumer health - Rhabdoid tumor.

MedlinePlus Health Information. consumer health - Brain Tumors.

MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[CommentIn] Childs Nerv Syst. 2009 Nov;25(11):1387; author reply 1389 [19636570.001]

[Cites] Pediatr Neurosurg. 2006;42(3):187-92 [16636624.001]

[Cites] J Neuropathol Exp Neurol. 2002 Mar;61(3):215-25; discussion 226-9 [11895036.001]

[Cites] Mod Pathol. 2005 Jul;18(7):951-8 [15761491.001]

[Cites] J Neurooncol. 1995;24(1):21-8 [8523069.001]

[Cites] J Neurooncol. 2005 Dec;75(3):309-13 [16195799.001]

[Cites] J Neurooncol. 2008 Jul;88(3):321-30 [18369529.001]

[Cites] Acta Neuropathol. 1992;83(4):445-8 [1575023.001]

[Cites] J Pediatr Hematol Oncol. 2002 Jun-Jul;24(5):337-42 [12142780.001]

[Cites] J Neurooncol. 1998 Dec;40(3):265-75 [10066100.001]

[Cites] J Neurosurg. 1996 Jul;85(1):56-65 [8683283.001]

[Cites] Neuropathology. 2002 Dec;22(4):252-60 [12564764.001]

[Cites] Neurol Med Chir (Tokyo). 1999 Jul;39(7):510-7; discussion 517-8 [10437379.001]

[Cites] Am J Surg Pathol. 2004 May;28(5):644-50 [15105654.001]

[Cites] Am J Surg Pathol. 2004 Nov;28(11):1485-91 [15489652.001]

[Cites] Acta Neuropathol. 2000 May;99(5):482-8 [10805090.001]

[Cites] Am J Surg Pathol. 1998 Sep;22(9):1083-92 [9737241.001]

[Cites] J Neuropathol Exp Neurol. 2005 May;64(5):391-7 [15892296.001]

[Cites] Ultrastruct Pathol. 1997 Jul-Aug;21(4):369-78 [9206002.001]

[Cites] Childs Nerv Syst. 2008 Jan;24(1):143-7 [17968559.001]

(PMID = 19212771.001).

[ISSN] 1433-0350

[Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

[ISO-abbreviation] Childs Nerv Syst

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

[Chemical-registry-number] 0 / Actins; 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / Desmin; 0 / Glial Fibrillary Acidic Protein; 0 / Mucin-1; 0 / S100 Proteins; 0 / SMARCB1 Protein; 0 / SMARCB1 protein, human; 0 / Synaptophysin; 0 / Transcription Factors; 0 / Vimentin; 68238-35-7 / Keratins

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Recent advances in embryonal tumours of the central nervous system.

INTRODUCTION: Embryonal tumours of the central nervous system (CNS) are the commonest malignant paediatric brain tumours.

This group includes medulloblastomas, supratentorial primitive neuroectodermal tumours, atypical teratoid/rhabdoid tumours, ependymoblastomas, and medulloepitheliomas.

[MeSH-major] Central Nervous System Neoplasms / embryology. Neoplasms, Germ Cell and Embryonal / genetics. Neoplasms, Germ Cell and Embryonal / pathology

COS Scholar Universe. author profiles.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] J Neurosci. 1997 Jan 15;17(2):530-42 [8987776.001]

[Cites] Pediatr Res. 1999 May;45(5 Pt 1):697-708 [10231868.001]

[Cites] Science. 1997 Aug 22;277(5329):1109-13 [9262482.001]

[Cites] Pediatr Neurosurg. 2000 Apr;32(4):187-91 [10940769.001]

[Cites] Semin Diagn Pathol. 1994 May;11(2):85-97 [7809510.001]

[Cites] Curr Biol. 1998 May 7;8(10):573-81 [9601641.001]

[Cites] Br J Cancer. 1991 Nov;64(5):959-61 [1931625.001]

[Cites] Lab Invest. 1990 Apr;62(4):498-509 [2159086.001]

[Cites] Genes Chromosomes Cancer. 2000 May;28(1):31-7 [10738300.001]

[Cites] Annu Rev Neurosci. 2001;24:677-736 [11520916.001]

[Cites] Genes Chromosomes Cancer. 2001 Jul;31(3):288-94 [11391800.001]

[Cites] J Neuropathol Exp Neurol. 1998 Feb;57(2):179-87 [9600210.001]

[Cites] Br J Cancer. 2001 Sep 1;85(5):705-12 [11531256.001]

[Cites] J Neurosurg Sci. 1991 Jan-Mar;35(1):23-30 [1890457.001]

[Cites] Childs Nerv Syst. 1998 Jan-Feb;14(1-2):74-8 [9548346.001]

[Cites] J Neuropathol Exp Neurol. 1991 Mar;50(2):134-44 [2010773.001]

[Cites] J Clin Oncol. 1999 Mar;17(3):832-45 [10071274.001]

[Cites] Nature. 1998 Jul 9;394(6689):203-6 [9671307.001]

[Cites] Neurol India. 2003 Mar;51(1):27-34 [12865511.001]

[Cites] Genes Chromosomes Cancer. 1997 Jan;18(1):50-8 [8993980.001]

[Cites] Cell. 1996 Jun 14;85(6):841-51 [8681379.001]

[Cites] Int J Cancer. 1999 Mar 1;80(5):689-92 [10048968.001]

[Cites] Cancer Genet Cytogenet. 1994 Nov;78(1):1-6 [7987794.001]

[Cites] J Clin Oncol. 2001 Jan 15;19(2):472-9 [11208841.001]

[Cites] Cancer Res. 1997 Sep 15;57(18):4042-7 [9307291.001]

[Cites] Indian J Med Res. 1989 Apr;90:91-102 [2547708.001]

[Cites] Hum Mol Genet. 1999 Feb;8(2):291-7 [9931336.001]

[Cites] J Clin Oncol. 2000 Mar;18(5):1027-35 [10694553.001]

[Cites] Pediatr Dev Pathol. 1998 Jan-Feb;1(1):79-84 [10463275.001]

[Cites] Hum Mol Genet. 1999 Dec;8(13):2359-68 [10556283.001]

[Cites] Oncogene. 1997 Jul 17;15(3):361-6 [9233770.001]

[Cites] J Neurosurg. 1990 Apr;72(4):572-82 [2319316.001]

[Cites] Mayo Clin Proc. 1994 Apr;69(4):359-65 [8170180.001]

[Cites] Cancer Res. 2003 Jan 1;63(1):140-8 [12517790.001]

[Cites] Prog Neurobiol. 2000 Jun;61(2):205-29 [10704998.001]

[Cites] J Cell Biol. 2000 Jan 24;148(2):385-97 [10648571.001]

[Cites] Cancer Metastasis Rev. 1987;5(4):343-65 [2882864.001]

[Cites] J Neuropathol Exp Neurol. 1972 Jan;31(1):27-53 [5060129.001]

[Cites] Cancer Res. 1997 Jul 1;57(13):2581-5 [9205058.001]

[Cites] Neurosci Lett. 1995 Aug 4;195(2):81-4 [7478273.001]

[Cites] Eur J Cancer. 1990 Apr;26(4):464-9 [2141512.001]

[Cites] Hum Pathol. 2002 May;33(5):564-9 [12094385.001]

[Cites] Am J Pathol. 2003 Jun;162(6):1763-9 [12759234.001]

[Cites] Br J Cancer. 1999 Jul;80(9):1322-31 [10424732.001]

[Cites] Histopathology. 1988 Jan;12(1):17-27 [3286469.001]

[Cites] Can J Neurol Sci. 1996 Nov;23(4):257-63 [8951203.001]

[Cites] Int J Radiat Oncol Biol Phys. 1990 Apr;18(4):723-45 [2323965.001]

[Cites] Cancer Res. 1997 Oct 1;57(19):4217-20 [9331079.001]

[Cites] Br J Cancer. 1997;76(10):1284-7 [9374372.001]

[Cites] Brain Pathol. 2003 Jul;13(3):376-85 [12946027.001]

[Cites] J Neuropathol Exp Neurol. 1993 Nov;52(6):655-66 [8229085.001]

[Cites] J Pediatr Hematol Oncol. 1998 Jan-Feb;20(1):18-25 [9482408.001]

[Cites] J Neurooncol. 1997 Nov;35(2):169-76 [9266455.001]

[Cites] Cancer. 1992 Aug 1;70(3):671-8 [1623482.001]

[Cites] Cancer Res. 2001 Oct 1;61(19):7039-43 [11585731.001]

[Cites] Cancer. 1999 Jul 15;86(2):331-9 [10421270.001]

[Cites] Acta Cytol. 1996 Mar-Apr;40(2):384-5 [8629434.001]

[Cites] Cancer Res. 1997 Oct 1;57(19):4187-90 [9331072.001]

[Cites] J Neurooncol. 2002 Aug;59(1):49-61 [12222838.001]

[Cites] Cancer Genet Cytogenet. 1997 Aug;97(1):39-53 [9242217.001]

[Cites] Int J Cancer. 1996 Jul 3;67(1):11-5 [8690510.001]

[Cites] J Neurosurg. 1990 Nov;73(5):710-4 [2213160.001]

[Cites] Pediatr Neurosurg. 2002 Sep;37(3):111-7 [12187055.001]

[Cites] Eur J Cancer. 2002 Jan;38(1):92-8 [11750845.001]

[Cites] J Biol Chem. 2000 Sep 15;275(37):28341-4 [10884376.001]

[Cites] Nat Genet. 1996 Nov;14(3):245-7 [8896548.001]

[Cites] Mod Pathol. 1990 Mar;3(2):164-70 [2109316.001]

[Cites] J Neurooncol. 1995;24(1):39-45 [8523074.001]

[Cites] Lancet. 1992 Aug 22;340(8817):480 [1354801.001]

[Cites] J Clin Oncol. 1997 Jul;15(7):2744-58 [9215849.001]

[Cites] Cancer. 2002 Jul 15;95(2):410-9 [12124842.001]

[Cites] J Pediatr Hematol Oncol. 1998 Nov-Dec;20(6):520-7 [9856671.001]

[Cites] Eur J Cancer. 2002 Mar;38(5):675-85 [11916550.001]

[Cites] Genes Dev. 1996 Nov 15;10(22):2849-58 [8918886.001]

[Cites] Cancer. 2002 Jan 15;94(2):552-60 [11900240.001]

[Cites] Cancer. 1971 Oct;28(4):977-83 [5111749.001]

[Cites] J Clin Oncol. 2001 Aug 1;19(15):3470-6 [11481352.001]

[Cites] Med Pediatr Oncol. 1995 Sep;25(3):166-78 [7623725.001]

[Cites] Brain Tumor Pathol. 2002;19(2):93-6 [12622139.001]

[Cites] J Neurooncol. 2002 Jul;58(3):271-9 [12187960.001]

[Cites] J Pediatr Hematol Oncol. 2003 Mar;25(3):198-203 [12621237.001]

[Cites] Brain Tumor Pathol. 1999;16(1):37-44 [10532422.001]

[Cites] J Neurosurg. 1987 Jan;66(1):80-7 [3783262.001]

[Cites] Clin Cancer Res. 1997 Mar;3(3):473-8 [9815707.001]

[Cites] Genomics. 1994 Sep 1;23(1):229-32 [7829075.001]

[Cites] Nat Genet. 1997 Sep;17(1):32-9 [9288095.001]

[Cites] Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9387-91 [7937775.001]

[Cites] Genes Chromosomes Cancer. 2000 Jan;27(1):44-51 [10564585.001]

[Cites] Genes Chromosomes Cancer. 1994 Mar;9(3):168-72 [7515658.001]

[Cites] J Neuropathol Exp Neurol. 1969 Jul;28(3):442-54 [5788941.001]

[Cites] J Neuropathol Exp Neurol. 2003 Jun;62(6):627-32 [12834107.001]

[Cites] Cancer Res. 1990 Apr 15;50(8):2347-50 [2180567.001]

[Cites] Cancer Res. 1990 Feb 1;50(3):587-91 [1967549.001]

[Cites] Oncologist. 2003;8(2):174-86 [12697942.001]

[Cites] Childs Nerv Syst. 1998 Jul;14 (7):312-6 [9726581.001]

[Cites] Cancer. 1985 Apr 1;55(7):1495-500 [3978542.001]

[Cites] Am J Pathol. 2000 Feb;156(2):433-7 [10666372.001]

[Cites] Mol Pathol. 2000 Dec;53(6):313-9 [11193050.001]

[Cites] J Biol Chem. 2000 Jan 7;275(1):565-70 [10617652.001]

[Cites] J Neurosurg. 1996 Jul;85(1):56-65 [8683283.001]

[Cites] J Neurosurg. 1997 Jan;86(1):13-21 [8988076.001]

[Cites] J Neurooncol. 2001 Mar;52(1):57-62 [11451203.001]

[Cites] Neuron. 1997 Jul;19(1):39-50 [9247262.001]

[Cites] Anticancer Res. 1996 Sep-Oct;16(5A):2687-92 [8917371.001]

[Cites] J Clin Oncol. 1999 Dec;17(12):3720-8 [10577843.001]

[Cites] Int J Cancer. 2000 Sep 20;89(5):395-402 [11008200.001]

[Cites] J Neurosci. 1994 May;14(5 Pt 2):3059-71 [8182459.001]

[Cites] Cancer Res. 1994 Nov 1;54(21):5649-51 [7923211.001]

[Cites] Am J Pathol. 1996 Mar;148(3):929-40 [8774147.001]

[Cites] Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12867-71 [7809137.001]

[Cites] Brain Tumor Pathol. 2002;19(1):15-22 [12455884.001]

[Cites] Brain. 1964 Jun;87:379-412 [14188281.001]

[Cites] Cancer Genet Cytogenet. 1988 Jan;30(1):91-101 [3422050.001]

[Cites] Ann Neurol. 1996 Apr;39(4):481-9 [8619526.001]

[Cites] Neurol Med Chir (Tokyo). 1999 Jul;39(7):510-7; discussion 517-8 [10437379.001]

[Cites] J Clin Oncol. 1998 Jul;16(7):2478-85 [9667267.001]

[Cites] Neurosurgery. 2000 Oct;47(4):888-901 [11014429.001]

[Cites] J Pediatr Hematol Oncol. 1997 Nov-Dec;19(6):510-5 [9407936.001]

[Cites] Pathology. 1999 Nov;31(4):337-44 [10643003.001]

[Cites] Am J Surg Pathol. 1992 Jul;16(7):687-93 [1530108.001]

[Cites] Clin Neuropathol. 1991 Jan-Feb;10(1):1-10 [2015720.001]

[Cites] J Neurooncol. 1996 Jul;29(1):103-12 [8817421.001]

[Cites] Mayo Clin Proc. 1990 Aug;65(8):1077-86 [2117687.001]

[Cites] J Neurosurg. 1999 Dec;91(6):971-7 [10584843.001]

[Cites] J Neurosurg. 1991 Jun;74(6):905-9 [2033450.001]

[Cites] Neuron. 1997 Jun;18(6):847-55 [9208852.001]

[Cites] Cancer Res. 1997 Mar 1;57(5):842-5 [9041183.001]

[Cites] Acta Neurochir (Wien). 1992;119(1-4):62-7 [1481754.001]

[Cites] J Neuropathol Exp Neurol. 2000 Oct;59(10):857-65 [11079775.001]

[Cites] J Neuropathol Exp Neurol. 2001 May;60(5):462-9 [11379821.001]

[Cites] Genes Chromosomes Cancer. 1996 Jan;15(1):54-63 [8824726.001]

[Cites] Genes Chromosomes Cancer. 2001 Jan;30(1):38-47 [11107174.001]

[Cites] N Engl J Med. 1995 Mar 30;332(13):839-47 [7661930.001]

[Cites] Curr Opin Neurobiol. 2000 Jun;10(3):392-9 [10851180.001]

[Cites] Cancer. 1999 Jun 15;85(12):2662-7 [10375116.001]

[Cites] Clin Cancer Res. 1996 Sep;2(9):1559-64 [9816333.001]

[Cites] Arch Pathol Lab Med. 2002 May;126(5):540-4 [11958658.001]

[Cites] Cancer Res. 2002 Jan 1;62(1):323-8 [11782395.001]

[Cites] Cancer Res. 1991 Sep 1;51(17):4721-3 [1873817.001]

[Cites] Cancer. 1981 Feb 15;47(4):772-9 [7226024.001]

[Cites] Pediatr Neurosurg. 1991-1992;17(5):245-50 [1668360.001]

[Cites] Am J Pathol. 1995 Feb;146(2):472-80 [7856756.001]

[Cites] AJNR Am J Neuroradiol. 2000 Oct;21(9):1757-65 [11039362.001]

[Cites] Cancer Genet Cytogenet. 1997 Sep;97(2):125-34 [9283596.001]

[Cites] Nat Genet. 2001 Oct;29(2):143-52 [11544480.001]

[Cites] Expert Rev Anticancer Ther. 2003 Oct;3(5):615-20 [14599085.001]

[Cites] Cancer Res. 1998 May 1;58(9):1798-803 [9581815.001]

[Cites] Adv Anat Pathol. 2002 Nov;9(6):345-50 [12409643.001]

[Cites] Clin Cancer Res. 2001 Aug;7(8):2425-33 [11489822.001]

[Cites] Neuropathol Appl Neurobiol. 2002 Aug;28(4):257-82 [12175339.001]

[Cites] J Neurosci. 1995 Apr;15(4):2656-67 [7722620.001]

[Cites] J Clin Oncol. 2004 Mar 15;22(6):971-4 [14970187.001]

[Cites] J Neurosurg. 1984 Oct;61(4):657-64 [6470775.001]

[Cites] Cancer Res. 1996 Jan 15;56(2):377-83 [8542595.001]

[Cites] Eur J Cancer. 1998 Sep;34(10):1592-7 [9893634.001]

[Cites] Cancer Genet Cytogenet. 1997 Aug;97(1):25-31 [9242214.001]

[Cites] Indian J Cancer. 1989 Dec;26(4):240-6 [2561483.001]

[Cites] J Clin Oncol. 1999 Jul;17(7):2127-36 [10561268.001]

[Cites] J Neuropathol Exp Neurol. 1983 Jan;42(1):1-15 [6296325.001]

[Cites] J Neurosurg. 1989 Apr;70(4):536-44 [2926493.001]

[Cites] Neuroradiology. 1989;31(4):369-70 [2797435.001]

[Cites] Cancer. 1993 May 1;71(9):2862-72 [8385567.001]

[Cites] Acta Neurochir (Wien). 1981;57(3-4):159-62 [7282443.001]

[Cites] Brain Pathol. 2002 Jan;12(1):36-44 [11770900.001]

[Cites] Br J Cancer. 1995 Mar;71(3):473-7 [7880726.001]

[Cites] Am J Med Genet. 1997 Mar 31;69(3):299-308 [9096761.001]

[Cites] Oncogene. 2001 Jun 28;20(29):3857-68 [11439349.001]

[Cites] Int J Radiat Oncol Biol Phys. 2000 Jun 1;47(3):573-84 [10837938.001]

[Cites] J Neuropathol Exp Neurol. 2000 Apr;59(4):333-7 [10759189.001]

[Cites] Cancer Res. 1991 Jan 15;51(2):639-43 [1670763.001]

[Cites] Nature. 2000 Aug 31;406(6799):1005-9 [10984056.001]

[Cites] J Neurosurg. 2001 Jul;95(1):82-8 [11453402.001]

[Cites] Int J Cancer. 1999 Apr 12;81(2):165-73 [10188714.001]

[Cites] Neuron. 1999 Jan;22(1):103-14 [10027293.001]

[Cites] Acta Neuropathol. 1998 Apr;95(4):325-32 [9560008.001]

[Cites] J Clin Oncol. 1999 Sep;17(9):2639-48 [10561337.001]

[Cites] Acta Neurochir (Wien). 1991;109(3-4):145-9 [1858533.001]

[Cites] Cancer Res. 1997 Aug 15;57(16):3526-31 [9270024.001]

[Cites] Cancer Res. 1999 Jan 1;59(1):74-9 [9892189.001]

[Cites] Cancer Res. 2002 Jul 1;62(13):3794-7 [12097291.001]

[Cites] Childs Nerv Syst. 2004 Jan;20(1):55-60 [14657995.001]

[Cites] Eur J Paediatr Neurol. 2003;7(2):53-66 [12697428.001]

[Cites] EMBO J. 1997 Apr 1;16(7):1647-55 [9130710.001]

[Cites] Tumori. 1995 Sep-Oct;81(5):338-46 [8804450.001]

[Cites] Acta Neuropathol. 2000 May;99(5):482-8 [10805090.001]

[Cites] Cancer Res. 1997 Jun 1;57(11):2085-8 [9187099.001]

[Cites] J Neurosurg. 1984 Aug;61(2):296-301 [6737054.001]

[Cites] Nature. 2002 Jan 24;415(6870):436-42 [11807556.001]

[Cites] Radiographics. 2003 Nov-Dec;23 (6):1613-37 [14615567.001]

[Cites] Bioessays. 1999 Dec;21(12):1021-30 [10580987.001]

[Cites] J Clin Oncol. 2001 May 15;19(10):2696-704 [11352962.001]

[Cites] J Mol Biol. 1999 Oct 22;293(2):187-98 [10529347.001]

[Cites] Mol Cell Biol. 2000 Dec;20(23):9055-67 [11074003.001]

[Cites] Nature. 1995 Nov 23;378(6555):386-90 [7477375.001]

[Cites] Cancer Res. 1999 Feb 1;59(3):711-9 [9973222.001]

[Cites] Br J Cancer. 1999 Apr;79(11-12):1843-7 [10206302.001]

[Cites] Cancer Res. 1997 Aug 1;57(15):3272-80 [9242460.001]

[Cites] Tumori. 1991 Apr 30;77(2):118-21 [2048223.001]

[Cites] Neurosurgery. 1993 Aug;33(2):301-5; discussion 305-6 [8396224.001]

[Cites] Curr Opin Cell Biol. 1995 Apr;7(2):148-55 [7612265.001]

[Cites] Hum Pathol. 1987 Apr;18(4):332-7 [3030922.001]

[Cites] Proc Natl Acad Sci U S A. 1995 Jun 6;92 (12 ):5709-13 [7777574.001]

[Cites] Arch Pathol Lab Med. 1995 Aug;119(8):734-43 [7646332.001]

[Cites] Genes Dev. 2000 Dec 1;14(23):2919-37 [11114882.001]

[Cites] Radiology. 1969 Dec;93(6):1351-9 [4983156.001]

[Cites] Cancer Res. 1998 Mar 1;58(5):896-9 [9500446.001]

[Cites] Acta Neurochir (Wien). 1995;132(1-3):59-65 [7754860.001]

[Cites] Cancer Res. 1988 Jan 1;48(1):175-80 [3334992.001]

[Cites] Cancer. 1973 Oct;32(4):890-7 [4751919.001]

[Cites] AJNR Am J Neuroradiol. 1994 Sep;15(8):1425-34 [7985559.001]

[Cites] Int J Cancer. 2001 Aug 1;93(3):445-9 [11433413.001]

[Cites] Am J Surg Pathol. 1998 Sep;22(9):1083-92 [9737241.001]

[Cites] Int J Oncol. 1996 May;8(5):901-10 [21544444.001]

[Cites] Cancer. 2000 May 1;88(9):2189-93 [10813733.001]

[Cites] Cancer. 1991 Aug 1;68(3):568-73 [2065277.001]

[Cites] Curr Opin Neurol. 2002 Dec;15(6):671-7 [12447104.001]

[Cites] Cancer Res. 1998 Sep 1;58(17):3932-41 [9731505.001]

[Cites] Cancer Res. 2002 Oct 15;62(20):5906-11 [12384556.001]

[Cites] J Pediatr Hematol Oncol. 2001 Oct;23(7):431-6 [11878577.001]

[Cites] J Clin Oncol. 2004 Mar 15;22(6):984-93 [14970185.001]

(PMID = 15682321.001).

[ISSN] 0256-7040

[Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

[ISO-abbreviation] Childs Nerv Syst

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] Germany

[Chemical-registry-number] 0 / Transcription Factors

[Number-of-references] 236

   

[Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Congenital tumors of the central nervous system.

Congenital tumors of the central nervous system (CNS) are often arbitrarily divided into "definitely congenital" (present or producing symptoms at birth), "probably congenital" (present or producing symptoms within the first week of life), and "possibly congenital" (present or producing symptoms within the first 6 months of life).

The prenatal diagnosis of congenital CNS tumors, while based on ultrasonography, has significantly benefited from the introduction of prenatal magnetic resonance imaging studies.

Teratomas constitute about one third to one half of these tumors and are the most common neonatal brain tumor.

They are often immature because of primitive neural elements and, rarely, a component of mixed malignant germ cell tumors.

Other tumors include astrocytomas, choroid plexus papilloma, primitive neuroectodermal tumors, atypical teratoid/rhabdoid tumors, and medulloblastomas.

The prognosis for patients with congenital tumors is generally poor, usually because of the massive size of the tumor.

[MeSH-major] Central Nervous System Neoplasms / congenital. Central Nervous System Neoplasms / diagnosis. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed / methods

MedlinePlus Health Information. consumer health - CT Scans.

MedlinePlus Health Information. consumer health - MRI Scans.

[Email] Email this result item

Email the results to the following email address:   [X] Close

[Cites] Pediatr Radiol. 1997 Sep;27(9):748-9 [9285737.001]

[Cites] J Pediatr Hematol Oncol. 2009 Sep;31(9):651-63 [19707161.001]

[Cites] Radiographics. 2002 Nov-Dec;22(6):1473-505 [12432118.001]

[Cites] Childs Nerv Syst. 2003 Aug;19(7-8):529-36 [12908112.001]

[Cites] Neuropadiatrie. 1973 Jan;4(1):46-63 [4739778.001]

[Cites] Childs Nerv Syst. 2003 Jun;19(5-6):292-7 [12750935.001]

[Cites] J Neurooncol. 2007 May;83(1):47-52 [17387433.001]

[Cites] AJNR Am J Neuroradiol. 1993 Mar-Apr;14 (2):426-9 [8456723.001]

[Cites] Orphanet J Rare Dis. 2008 Nov 25;3:32 [19032739.001]

[Cites] Pediatr Neurosurg. 1993 Mar-Apr;19(2):57-62 [8443097.001]

[Cites] AJR Am J Roentgenol. 1990 Sep;155(3):587-93 [2167004.001]

[Cites] Neuroradiology. 1984;26(6):523-6 [6504322.001]

[Cites] Pediatr Neurol. 2007 Feb;36(2):128-31 [17275668.001]

[Cites] J Neuropathol Exp Neurol. 1964 Apr;23:280-92 [14137675.001]

[Cites] Arch Dis Child. 2006 Jun;91(6):520 [16714726.001]

[Cites] J Neurosurg. 1988 Oct;69(4):604-9 [3047342.001]

[Cites] AJNR Am J Neuroradiol. 1993 May-Jun;14 (3):529-36 [8517336.001]

[Cites] Histopathology. 1992 Jul;21(1):43-9 [1634201.001]

[Cites] Pediatr Neurol. 2002 Oct;27(4):249-61 [12435562.001]

[Cites] J Neurosurg. 2007 Mar;106(3 Suppl):232-6 [17465391.001]

[Cites] Pediatr Neurol. 2009 Dec;41(6):453-6 [19931170.001]

[Cites] Fetal Pediatr Pathol. 2007 May-Jun;26(3):109-18 [17886021.001]

[Cites] J Obstet Gynaecol. 2007 Apr;27(3):314-7 [17464824.001]

[Cites] Childs Nerv Syst. 1986;2(5):262-5 [3791286.001]

[Cites] Pediatr Neurol. 2002 Sep;27(3):230-3 [12393136.001]

[Cites] Pediatr Neurosurg. 2000 Nov;33(5):265-269 [11155065.001]

[Cites] Childs Nerv Syst. 1990 Sep;6(6):331-4 [2257546.001]

[Cites] Am J Perinatol. 2009 Jun;26(6):453-66 [19396744.001]

[Cites] J Clin Neurosci. 1998 Jul;5(3):265-9 [18639031.001]

[Cites] Am J Dis Child. 1974 Sep;128(3):381-3 [4414783.001]

[Cites] J Neurosurg. 1998 Apr;88(4):757-60 [9525724.001]

[Cites] Clin Neuropathol. 2001 Sep-Oct;20(5):181-9 [11594502.001]

[Cites] Clin Cancer Res. 2009 Apr 1;15(7):2463-71 [19276247.001]

[Cites] J Clin Ultrasound. 1986 May;14(4):304-6 [3084590.001]

[Cites] Pediatr Radiol. 2009 Nov;39(11):1158-72 [19774372.001]

[Cites] Pediatr Radiol. 2008 Nov;38(11):1235-8 [18663441.001]

[Cites] Curr Opin Pediatr. 2009 Jun;21(3):344-9 [19417664.001]

[Cites] Fetal Pediatr Pathol. 2004 Sep-Dec;23(5-6):295-303 [16137166.001]

[Cites] Fetal Diagn Ther. 2008;23(1):1-4 [17934288.001]

[Cites] Acta Neuropathol. 2002 Jan;103(1):78-81 [11837749.001]

[Cites] Fetal Diagn Ther. 2008;23 (4):267-70 [18417992.001]

[Cites] Acta Pathol Jpn. 1985 Sep;35(5):1273-7 [4083009.001]

[Cites] Pediatr Dermatol. 2005 Jul-Aug;22(4):309-13 [16060865.001]

[Cites] Pediatr Neurosurg. 1998 Aug;29(2):105-10 [9792966.001]

[Cites] Neuroradiology. 2008 May;50(5):447-52 [18345534.001]

[Cites] Neurosurgery. 1991 Jul;29(1):8-13 [1651461.001]

[Cites] J Child Neurol. 1993 Oct;8(4):389-94 [8228038.001]

[Cites] Pediatr Neurosurg. 1997 Feb;26(2):97-102 [9419039.001]

[Cites] J Neurooncol. 1993 Feb;15(2):157-63 [8509820.001]

[Cites] AJNR Am J Neuroradiol. 2006 May;27(5):962-71 [16687525.001]

[Cites] J Pediatr. 2001 Jul;139(1):117-23 [11445804.001]

[Cites] Pediatr Radiol. 1995;25(7):540-3 [8545186.001]

[Cites] J Comput Assist Tomogr. 1988 Sep-Oct;12(5):858-61 [3049711.001]

[Cites] Surg Neurol. 1984 Jun;21(6):597-609 [6372141.001]

[Cites] Acta Neuropathol. 2007 Aug;114(2):97-109 [17618441.001]

[Cites] Neuroradiology. 2000 Sep;42(9):657-61 [11071438.001]

[Cites] Brain Pathol. 1993 Jul;3(3):275-81 [8293187.001]

[Cites] Pediatr Neurosurg. 1997 Aug;27(2):108-11 [9520084.001]

[Cites] Neurosurgery. 1993 Jan;32(1):131-3; discussion 133-4 [8421542.001]

[Cites] Fetal Diagn Ther. 2003 May-Jun;18(3):137-9 [12711864.001]

[Cites] Am J Perinatol. 2007 Oct;24(9):507-9 [17909991.001]

[Cites] Pediatr Neurol. 2007 Jun;36(6):402-6 [17560503.001]

[Cites] Arch Dis Child Fetal Neonatal Ed. 2006 Sep;91(5):F373 [16923937.001]

[Cites] Pediatr Radiol. 2006 Feb;36(2):126-32 [16341528.001]

[Cites] Radiographics. 2004 Jul-Aug;24(4):1165-70 [15256635.001]

[Cites] Pathol Oncol Res. 2001;7(1):67-71 [11349224.001]

[Cites] AJR Am J Roentgenol. 1994 May;162(5):1160 [8166003.001]

[Cites] Neuroradiology. 2001 Nov;43(11):934-40 [11760796.001]

[Cites] Cancer Res. 2002 Jan 1;62(1):323-8 [11782395.001]

[Cites] Pediatr Neurosurg. 2007;43(2):125-9 [17337925.001]

[Cites] Pediatr Neurosurg. 2008;44(1):1-8 [18097184.001]

[Cites] J Neurosurg. 2006 Mar;104(3 Suppl):188-91 [16572636.001]

[Cites] Pediatr Neurosurg. 2008;44(4):304-12 [18504417.001]

[Cites] Pediatr Dev Pathol. 2009 Sep-Oct;12(5):398-403 [19883237.001]

[Cites] Neuroradiology. 1999 May;41(5):369-75 [10379597.001]

[Cites] Childs Brain. 1984;11(5):342-8 [6499569.001]

[Cites] Cancer. 1995 Jun 15;75(12):2971-7 [7773950.001]

[Cites] Childs Nerv Syst. 1990 May;6(3):179-82 [2162735.001]

[Cites] Childs Nerv Syst. 1990 Dec;6(8):462-4 [2095307.001]

[Cites] Fetal Diagn Ther. 1998 Nov-Dec;13(6):339-42 [9933815.001]

[Cites] Pediatr Radiol. 1994;24(2):141-2 [8078719.001]

[Cites] J Neurosurg. 1951 May;8(3):315-9 [14841542.001]

[Cites] Radiographics. 2005 Jan-Feb;25(1):215-42 [15653597.001]

[Cites] Pediatr Neurosurg. 2008;44(5):422-5 [18703892.001]

[Cites] J Comput Assist Tomogr. 1988 Jan-Feb;12(1):10-20 [3335647.001]

[Cites] Arch Dermatol. 1996 Mar;132(3):307-11 [8607636.001]

[Cites] J Perinatol. 1995 Sep-Oct;15(5):426-8 [8576765.001]

[Cites] AJNR Am J Neuroradiol. 2009 May;30(5):1005-13 [19213817.001]

[Cites] Surg Neurol. 1992 Oct;38(4):273-6 [1440215.001]

[Cites] Pediatr Blood Cancer. 2005 Dec;45(7):986-90 [15702481.001]

[Cites] J Pediatr Surg. 1974 Jun;9(3):389-98 [4843993.001]

[Cites] J Magn Reson Imaging. 2001 Jul;14(1):78-82 [11436218.001]

[Cites] Pediatr Pathol Lab Med. 1995 Nov-Dec;15(6):949-56 [8705205.001]

[Cites] Childs Nerv Syst. 2009 Nov;25(11):1495-500 [19484251.001]

[Cites] Neuroradiology. 2004 Dec;46(12):1039-43 [15551129.001]

[Cites] Neurosurgery. 1997 Aug;41(2):388-94; discussion 394-5 [9257306.001]

[Cites] Neurosurg Focus. 2005 Jun 15;18(6A):E4 [16048290.001]

[Cites] Prenat Diagn. 1990 Oct;10 (10 ):623-9 [2274487.001]

[Cites] Epilepsy Res. 2009 Nov;87(1):88-94 [19619986.001]

[Cites] Surg Neurol. 1987 May;27(5):466-8 [3563861.001]

[Cites] Brain Dev. 2005 Apr;27(3):164-71 [15737696.001]

[Cites] J Neurosurg. 2006 Dec;105(6 Suppl):473-9 [17184081.001]

[Cites] Pediatr Neurol. 2009 Oct;41(4):291-3 [19748050.001]

[Cites] Pediatr Neurol. 2002 Nov;27(5):333-42 [12504200.001]

[Cites] J Pediatr Hematol Oncol. 2009 Dec;31(12):985-8 [19956025.001]

[Cites] Eur J Obstet Gynecol Reprod Biol. 1998 Oct;81(1):115-7 [9846725.001]

[Cites] AJNR Am J Neuroradiol. 2008 Apr;29(4):807-13 [18223093.001]

[Cites] Pediatr Blood Cancer. 2009 Jul;53(1):124-6 [19309717.001]

[Cites] Pediatr Radiol. 1999 Jun;29(6):441-3 [10369901.001]

[Cites] Childs Nerv Syst. 1991 Apr;7(2):112-4 [1863930.001]

[Cites] Ultrasound Obstet Gynecol. 1995 Jan;5(1):63-6 [7850596.001]

[Cites] Eur J Pediatr Surg. 2002 Dec;12(6):366-74 [12548487.001]

[Cites] Cancer Res. 1997 Jan 15;57(2):304-9 [9000573.001]

(PMID = 20428859.001).

[ISSN] 1432-1920

[Journal-full-title] Neuroradiology

[ISO-abbreviation] Neuroradiology

[Language] eng

[Publication-type] Journal Article

[Publication-country] Germany