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Items 1 to 57 of about 57
1. Kelly P, Dobbs SP, McCluggage WG: Endometrial hyperplasia involving endometrial polyps: report of a series and discussion of the significance in an endometrial biopsy specimen. BJOG; 2007 Aug;114(8):944-50

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Rarely, a hyperplasia, either complex or atypical in type, is identified within a polyp in a biopsy or polypectomy specimen.
  • Currently, it is not known whether the hyperplasia is likely to be confined to the polyp or also involve nonpolypoid endometrium.
  • We aim to assess the likelihood of hyperplasia being confined to an endometrial polyp.
  • DESIGN: In this study, we identified 32 women from pathology archives in whom endometrial hyperplasia was present within a polyp.
  • RESULTS: The hyperplasias were complex (n = 23) or atypical (n = 9) in type.
  • In 14 of 27 (52%) women in whom nonpolypoid endometrium was available for histological evaluation, either on the original biopsy or in a follow-up specimen, hyperplasia involved the nonpolypoid endometrium, and in three other women, hyperplasia was present in a polyp in follow-up specimens.
  • Women with atypical hyperplasia in a polyp were slightly more likely to have hyperplasia in the surrounding endometrium than those with complex hyperplasia.
  • CONCLUSIONS: Our study illustrates that the risk of endometrial hyperplasia in a polyp concurrently involving nonpolypoid endometrium is significant.
  • We suggest a strategy for the management of women with hyperplasia identified within an endometrial polyp in a biopsy or polypectomy specimen.

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  • (PMID = 17565613.001).
  • [ISSN] 1471-0528
  • [Journal-full-title] BJOG : an international journal of obstetrics and gynaecology
  • [ISO-abbreviation] BJOG
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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2. Liu DC, Yang ZL, Yang LP: [Expression of enhancer of zesle homolog 2 and phosphatase and tension homolog and its clinicopathological significance in benign and malignant lesion of gallbladder]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2008 Jul;33(7):618-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: EnVision immunohistochemical method was used to detect the expressive levels of EZH2 and PTEN in routinely paraffin-embedded sections in the resected specimens of gallbladder adenocarcinoma (n = 108), peritumoral tissues (n = 46), adenomatous polyp(n = 15), and chronic cholecystitis (n = 35).
  • RESULTS: The positive rate of EZH2 was significantly higher in gallbladder adenocarcinoma than that in peritumoral tissues (chi(2) = 24.49, P < 0.01), adenomatous polyp(chi(2) = 11.68, P < 0.01), and chronic cholecystitis (chi(2) = 31.62, P < 0.01).
  • The benign lesions in the positive cases of EZH2 and (or) the negative ones of PTEN showed the moderately- or severely- atypical hyperplasia of gallbladder epithelium.
  • The positive rate of PTEN was significantly lower in gallbladder adenocarcinoma than that in peritumoral tissues(n = 20.20, P < 0.01), adenomatous polyp(chi(2)=10.81, P<0.01), and chronic cholecystitis (n = 29.83, P < 0.01).The positive rates of EZH2 were significantly lower in the highly-differentiated adenocarcinoma, the maximal diameter of mass < 2 cm, non-metastasis of lymphnodes, and non-infiltration of regional tissues than those in the moderately or low-differentiated adenocarcinoma, the maximal diameter > or = 2 cm, metastasis of lymphnode, and infiltration of regional tissues (P < 0.05 or P < 0.01).

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  • (PMID = 18667776.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / Transcription Factors; EC 2.1.1.43 / EZH2 protein, human; EC 2.1.1.43 / Polycomb Repressive Complex 2; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
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3. Buecher B, Bezieau S, Dufilhol C, Cauchin E, Heymann MF, Mosnier JF: [Emerging concepts in colorectal serrated polyps]. Gastroenterol Clin Biol; 2007 Jan;31(1):39-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • During the past few years, another type of serrated polyp with only very subtle proliferation abnormalities has been described.
  • These atypical serrated polyps may occur either sporadically or in the context of colorectal polyposis.

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  • (PMID = 17273130.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 90
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4. Allison KH, Reed SD, Voigt LF, Jordan CD, Newton KM, Garcia RL: Diagnosing endometrial hyperplasia: why is it so difficult to agree? Am J Surg Pathol; 2008 May;32(5):691-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sample adequacy, hyperplasia volume, presence of metaplasia, or endometrial polyp were also scored.
  • The percent specific agreement was 90.3% for no hyperplasia, 31.1% for simple hyperplasia, 51.1% for complex hyperplasia, 49.8% for atypical hyperplasia, and 57.5% for adenocarcinoma.
  • Architectural crowding, architectural complexity, or the presence of a polyp were all associated with diagnostic disagreement (P<0.0001).

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  • (PMID = 18347507.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / R01 HD044813; United States / NICHD NIH HHS / HD / R01 HD044813-04
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS103495; NLM/ PMC2682169
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5. Rittenbach J, Cao JD, Weiss LM, Rowsell EH, Chick W, Wang J: Primary diffuse large B-cell lymphoma of the uterus presenting solely as an endometrial polyp. Int J Gynecol Pathol; 2005 Oct;24(4):347-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary diffuse large B-cell lymphoma of the uterus presenting solely as an endometrial polyp.
  • We report a primary diffuse large B-cell lymphoma of endometrial polyp in a 44-year-old woman who presented with irregular vaginal spotting and was found to have a polyp protruding from the cervical os.
  • Histology of the polyp showed an atypical diffuse infiltration by large, mononuclear cells within the stroma and between endometrial glands in one of the polypoid fragments.
  • Staging procedures including detailed gynecology examination, body computed tomography scan, and bone marrow examination, as well as total hysterectomy, showed no evidence of lymphoma outside of the polyp.
  • To our knowledge, this represents the first well-documented instance of primary lymphoma of the uterus presenting as an endometrial polyp.
  • The differential diagnosis of endometrial biopsies containing an atypical lymphoid infiltrate should include the rather rare possibility of primary uterine lymphoma arising in an endometrial polyp.

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  • (PMID = 16175080.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Garuti G, Centinaio G, Luerti M: Outpatient hysteroscopic polypectomy in postmenopausal women: a comparison between mechanical and electrosurgical resection. J Minim Invasive Gynecol; 2008 Sep-Oct;15(5):595-600
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The diagnostic phase was immediately followed by polyp resection, alternatively allocating the patients to mechanical or electrosurgical polypectomy.
  • Nine patients were excluded because of severe pelvic pain arising in the diagnostic phase or the finding of an oversize polyp requiring an estimated time of more than 30 minutes to be removed in the office setting.
  • Clinical variables (i.e., age, age at menopause, parity, polyp size, and number) were similar in the 2 study arms.
  • Among the considered clinical variables, effectiveness of resection was significantly related to age of patients (p=.04) and polyp size (p=.004).
  • Atypical polyp histology occurred in 9 (8.8%) patients, 5 of whom were asymptomatic.
  • CONCLUSION: Outpatient see-and-treat polypectomy represents a safe and effective alternative to resectoscopic polypectomy, leading to a complete polyp excision in about 80% of postmenopausal patients.
  • No differences in the rate of polyp excision, surgical time, or induced pelvic discomfort were observed between electrosurgical and mechanical techniques.

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  • (PMID = 18722972.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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7. Al-Qudah MA: Sphenochoanal polyp: current diagnosis and management. Ear Nose Throat J; 2010 Jul;89(7):311-7
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  • [Title] Sphenochoanal polyp: current diagnosis and management.
  • The presence of a choanal polyp in an atypical location can lead to diagnostic confusion and exploration of the wrong sinus at surgery.
  • The author reports the case of a 15-year-old girl who was diagnosed with a sphenochoanal polyp.

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  • (PMID = 20628989.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Jung YM, Lee HS, Lee DH, Jeong YJ, Choi TH, Lee SH, Park YS, Hwang JH, Kim JW, Jeong SH, Kim N: [Clinical significance of incidentally detected eosinophilic esophagitis with pathologic review]. Korean J Gastroenterol; 2010 Mar;55(3):162-8
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  • Endoscopic findings were whitish exudates or granules (57%), esophageal polyp (29%), and hyperemic change (14%).
  • Our results suggest that Korean patients with eosinophilic esophagitis showed symptoms mimicking gastroesophageal reflux disease and atypical endoscopic findings.

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  • (PMID = 20357526.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Korea (South)
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9. Parada D, Moreira O, Gledhill T, Luigii JC, Páez A, Pardo M: Cellular pseudosarcomatous fibroepithelial stromal polyp of the renal pelvis. APMIS; 2005 Jan;113(1):70-4
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  • [Title] Cellular pseudosarcomatous fibroepithelial stromal polyp of the renal pelvis.
  • Cellular pseudosarcomatous fibroepithelial stromal polyp is an underrecognized lesion described in the lower female genital tract.
  • We here report the clinical, histological, and immunohistochemical features of a cellular pseudosarcomatous fibroepithelial stromal polyp located in the renal pelvis.
  • Atypical stromal cells and atypical mitoses were also found.
  • This case represents a typical cellular pseudosarcomatous fibroepithelial stromal polyp, probably developing from a reactive hyperplastic process involving the subepithelial stroma.

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  • (PMID = 15676018.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Desmin; 0 / KRT7 protein, human; 0 / Keratin-7; 0 / Receptors, Progesterone; 0 / Vimentin; 68238-35-7 / Keratins
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10. Tsuzuki T, Epstein JI: Fibroepithelial polyp of the lower urinary tract in adults. Am J Surg Pathol; 2005 Apr;29(4):460-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibroepithelial polyp of the lower urinary tract in adults.
  • The last morphologic pattern (Pattern 3) consisted of a polypoid lesion with secondary tall finger-like projections, which was seen in 3 cases.
  • One lesion contained atypical degenerative-appearing stromal cells.
  • Recognition of the precise histologic features of fibroepithelial polyp can facilitate its correct diagnosis.

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  • (PMID = 15767798.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Mercer SE, Khalil D, Emanuel PO, Goldenberg G: Verrucous carcinoma masquerading as a giant fibroepithelial polyp. Int J Surg Pathol; 2010 Oct;18(5):347-51
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  • [Title] Verrucous carcinoma masquerading as a giant fibroepithelial polyp.
  • The authors report a case of a verrucous carcinoma (VC) of the buttocks clinically simulating a giant (6.5 cm in length and 5.4 cm in greatest diameter) fibroepithelial polyp (FEP) capped by a large cutaneous horn.
  • Presentation of VC as a FEP is unusual and demonstrates the necessity of maintaining a high level of clinical suspicion of anogenital growths, particularly those involving atypical features such as ulceration or the presence of a cutaneous horn.

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  • (PMID = 20667928.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Cathro HP, Patterson JW, Wick MR: Cutaneous pseudosarcomatous polyp: a recently described lesion. Ann Diagn Pathol; 2008 Dec;12(6):440-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous pseudosarcomatous polyp: a recently described lesion.
  • Three cases of cutaneous pseudosarcomatous polyp, a lesion recently described in the dermatopathology literature, are reported here.
  • All 3 had the typical architecture of a fibroepithelial polyp (acrochordon) with widely separated stellate cells occupying a myxoid to collagenous stroma.
  • Markedly pleomorphic stellate cells were widely dispersed, with an increased density of atypical cells beneath the epidermis and in small foci of adipose tissue in 1 case.
  • Only rare mitotic figures were identified in 2 cases, but 1 showed atypical forms.
  • Immunohistochemically, the atypical cells reacted diffusely for vimentin and variably for CD34 and factor XIIIa, but they lacked smooth muscle actin and desmin.

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  • (PMID = 18995210.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Vimentin; EC 2.3.2.13 / Factor XIIIa
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13. Shibahara K, Haraguchi Y, Sasaki I, Kiyonari H, Oishi T, Iwashita A, Maehara Y, Sugimachi K: A case of gastric hyperplastic polyp with malignant transformation. Hepatogastroenterology; 2005 Jan-Feb;52(61):319-21
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  • [Title] A case of gastric hyperplastic polyp with malignant transformation.
  • In this paper we report a case of hyperplastic polyp with malignant transformation.
  • The first gastroscopy revealed a semi-pedunculated polyp beneath the esophageal-cardiac junction, 1.5cm in diameter and slightly reddish with smooth surface.
  • Histological findings showed a hyperplastic polyp.
  • In 1996, the biopsy specimen showed an atypical epithelium and the polyp was removed by snear polypectomy.
  • Immunohistochemically, p53 and Ki-67 immunostaining showed positive in the carcinoma portion of the adenocarcinoma bearing a hyperplastic polyp in the stomach.

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  • (PMID = 15783059.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53
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14. Cappell MS, Batke M: Invasive cancer in a diminutive rectal polyp amidst internal hemorrhoids detected by rectal retroflexion. South Med J; 2010 Sep;103(9):943-6
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  • [Title] Invasive cancer in a diminutive rectal polyp amidst internal hemorrhoids detected by rectal retroflexion.
  • A diminutive rectal polyp amidst internal hemorrhoids, detected by rectal retroflexion during colonoscopy, was shown to harbor invasive rectal adenocarcinoma by colonoscopic biopsy.
  • Initially this lesion had appeared to be a relatively innocuous prominent anorectal mucosal fold and was recognized as a diminutive polyp only after careful rectal retroflexion during colonoscopy.
  • This report emphasizes that lesions just above the anorectal junction with atypical endoscopic features for internal hemorrhoids should be carefully examined at rectal retroflexion and that polyps or suspicious lesions amidst internal hemorrhoids identified during colonoscopy should be snared or at least biopsied, even if small.
  • This case report also illustrates how easily an early cancer in a diminutive colonic polyp can be missed when in difficult areas of colonoscopic inspection, such as behind a colonic fold or immediately above the anus.

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  • (PMID = 20689479.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Semczuk A, Skorupski P, Olcha P, Skomra D, Rechberger T, Gogacz M: Giant uterine leiomyomas causing bilateral hydronephrosis coexisting with endometrial cancer in polyp: a case study. Eur J Gynaecol Oncol; 2009;30(3):344-6
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  • [Title] Giant uterine leiomyomas causing bilateral hydronephrosis coexisting with endometrial cancer in polyp: a case study.
  • We report a case of giant uterine leiomyomas causing bilateral hydronephrosis coexisting with endometrial cancer (EC) deriving from a uterine polyp.
  • Histopathological examination revealed multiple uterine leiomyomas with calcification and partial necrosis, and well-differentiated (G1), endometrioid-type EC (Stage IA) concomitant with atypical endometrial hyperplasia, deriving from a uterine polyp.

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  • (PMID = 19697639.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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16. Kxmel'nitskaia NM, Neĭshtadt EL, Khalimdzhanov ZK: [Difficulties and mistakes in the diagnosis of atypical endometrial hyperplasia]. Arkh Patol; 2006 Nov-Dec;68(6):39-42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Difficulties and mistakes in the diagnosis of atypical endometrial hyperplasia].
  • 687 endometrial biopsy specimens with morphological diagnosis "atypical endometrial hyperplasia" were examined by pathologists from the city cancer.
  • They revealed atypical endometrial hyperplasia in 47 (6.8%) cases, endometrial adenocarcinoma in 54 (7.9%), typical hyperplasia in 211 (30.7%), polyp in 165 (24%), proliferative endometrium in 89 (13.0%), secretory endometrium in 80 (11.7%), and atrophic endometrium in 10 (1.4%).
  • Hysterectomy was performed in atypical endometrial hyperplasia.
  • Comparison of the diagnoses revealed atypical endometrial hyperplasia in 14 (17.9%) cases, endometrial adenocarcinoma in 41 (52.7%), typical endometrial hyperplasia in 21 (26.9%), and polyp in 2 (2.5%).

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  • (PMID = 17290894.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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17. Abu J, Ireland D, Brown L: Adenosarcoma of an endometrial polyp in a 27-year-old nulligravida: a case report. J Reprod Med; 2007 Apr;52(4):326-8

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  • [Title] Adenosarcoma of an endometrial polyp in a 27-year-old nulligravida: a case report.
  • It consists of benign or atypical neoplastic glands within a sarcomatous stroma and represents approximately 8% of all uterine sarcomas.
  • CASE: Endometrial polyp adenosarcoma occurred in a 27-year-old, nulligravid woman who presented with intermenstrual and postcoital bleeding.
  • CONCLUSION: A clinical dilemma was encountered in the management of a young woman with endometrial polyp adenosarcoma because of the necessity to preserve her fertility.

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  • (PMID = 17506376.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Scrimin F, Wiesenfeld U, Candiotto A, Inglese S, Ronfani L, Guaschino S: Resectoscopic treatment of atypical endometrial polyps in fertile women. Am J Obstet Gynecol; 2008 Oct;199(4):365.e1-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Resectoscopic treatment of atypical endometrial polyps in fertile women.
  • After 5 years, we found no difference in the 2 groups regarding recurrence of atypical polyps.
  • CONCLUSION: Conservative resectoscopic treatment may be considered in fertile women with atypical polyps if polyp base and surrounding endometrium are benign.

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  • (PMID = 18928975.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
  • [Chemical-registry-number] 5W7SIA7YZW / Levonorgestrel
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19. MacPhail CM, Innocenti CM, Kudnig ST, Veir JK, Lappin MR: Atypical manifestations of feline inflammatory polyps in three cats. J Feline Med Surg; 2007 Jun;9(3):219-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical manifestations of feline inflammatory polyps in three cats.
  • Treatment consists of traction and avulsion of the polyp with or without ventral bulla osteotomy (VBO) to remove the epithelial lining of the tympanic bulla.
  • (1) concurrent otic and nasopharyngeal polyps, (2) potential association with chronic viral infection, (3) polyp development in the contralateral middle ear, (4) CT appearance of the skull following VBO, and (5) development of secondary pulmonary hypertension.

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  • (PMID = 17241805.001).
  • [ISSN] 1098-612X
  • [Journal-full-title] Journal of feline medicine and surgery
  • [ISO-abbreviation] J. Feline Med. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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20. Saad RS, Takei H, Liu YL, Silverman JE, Lipscomb JT, Ruiz B: Clinical significance of a cytologic diagnosis of atypical glandular cells, favor endometrial origin, in Pap smears. Acta Cytol; 2006 Jan-Feb;50(1):48-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical significance of a cytologic diagnosis of atypical glandular cells, favor endometrial origin, in Pap smears.
  • OBJECTIVE: To evaluate the significance of a diagnosis of atypical glandular cells, favor endometrial origin (AGC-EM), using cytohistologic correlation.
  • The remaining 33 patients had benign histology, including benign endometrium, endometrial polyp, tubal metaplasia, cystic endometrial atrophy and cervical microglandular hyperplasia.
  • Of the patients with cytologic follow-up, 2 had Pap smears showing atypical squamous cells of undetermined significance, while the remainder had negative results.


21. Scrimin F, Mangino FP, Wiesenfeld U, Candiotto A, Guaschino S: Is resectoscopic treatment of atypical endometrial polyps a safe option? Am J Obstet Gynecol; 2006 Nov;195(5):1328-30
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  • [Title] Is resectoscopic treatment of atypical endometrial polyps a safe option?
  • OBJECTIVE: This study was undertaken to evaluate the long-term efficacy and prognosis of hysteroscopic resection and coagulation of the polyp base of endometrial polyps with focal atypia in postmenopausal women.
  • Patients with atypia in the polyp base were excluded.
  • CONCLUSION: Adenomatous polyps with atypia can be treated resectoscopically if the treatment is associated with an accurate histologic examination of the polyp base and its eventual involvement and the features of the remaining uterine mucosa.

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  • (PMID = 16643815.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Rahimi S, Marani C, Renzi C, Natale ME, Giovannini P, Zeloni R: Endometrial polyps and the risk of atypical hyperplasia on biopsies of unremarkable endometrium: a study on 694 patients with benign endometrial polyps. Int J Gynecol Pathol; 2009 Nov;28(6):522-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endometrial polyps and the risk of atypical hyperplasia on biopsies of unremarkable endometrium: a study on 694 patients with benign endometrial polyps.
  • Hysteroscopic removal of endometrial polyps with 2 endometrial biopsies far from the base of the polyp were performed.
  • The weight of each polyp was determined.
  • At multivariable analysis, postmenopausal women with larger polyps had a 3.6-fold higher likelihood of atypia (odds ratio=3.6; 95% confidence interval: 1.3-10.3); in premenopause the likelihood of atypia was significantly associated with polyp weight and age above 40 years.

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  • (PMID = 19851198.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Seshamani M, Einhorn E, Mirza N: Atypical carcinoid of the larynx and potential complications of the carcinoid syndrome: a case report. Ear Nose Throat J; 2009 Jan;88(1):E1
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  • [Title] Atypical carcinoid of the larynx and potential complications of the carcinoid syndrome: a case report.
  • During evaluation, flexible laryngoscopy incidentally detected a left interarytenoid polyp.

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  • (PMID = 19172557.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Zhao H, He X, Pu Z, Wang Q: [Expression of Skp2 and PTEN and its correlation in glottic carcinoma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Aug;22(15):688-91
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  • METHOD: Formalin-fixed and paraffin-embedded tissues, which came from 42 cases of glottic carcinoma and 16 cases of atypical hyperplasia of vocal fold and 27 cases of vocal cord polyp, were detected for the expression of Skp2, PTEN by SP immunohistochemistry, then we analyzed the result statistically.
  • RESULT: The expression rates of Skp2 protein in vocal cord polyp, atypical hyperplasia of vocal cord and glottic carcinoma were 11.11%, 37.50%, 40.48% respectively.
  • There was significant difference among them (P < 0.01); the expression rates of PTEN protein in vocal cord polyp, atypical hyperplasia of vocal cord and glottic carcinoma were 100.00%, 75.00%, 52.38% respectively.

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  • (PMID = 18950007.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / S-Phase Kinase-Associated Proteins; EC 3.1.3.67 / PTEN Phosphohydrolase
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25. Fernández-Parra J, Rodríguez Oliver A, López Criado S, Parrilla Fernández F, Montoya Ventoso F: Hysteroscopic evaluation of endometrial polyps. Int J Gynaecol Obstet; 2006 Nov;95(2):144-8

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  • RESULT: Carcinoma was found in only 3.9% of the women who consulted for menopausal metrorrhagia and were diagnosed as having a polyp.
  • Hysteroscopy had a sensitivity of 36% and a specificity of 98% for a diagnosis of cancerous polyp or atypical hyperplasia.

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  • (PMID = 16920120.001).
  • [ISSN] 0020-7292
  • [Journal-full-title] International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [ISO-abbreviation] Int J Gynaecol Obstet
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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26. O'Brien MJ: Hyperplastic and serrated polyps of the colorectum. Gastroenterol Clin North Am; 2007 Dec;36(4):947-68, viii
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  • The serrated polyp pathway is a histopathological sequence that begins in a hyperplastic polyp, or precursor serrated aberrant crypt focus, and has the potential to end in a colonic adenocarcinoma that is CIMP-high and, in most cases, also MSI.
  • There is evidence that aberrant CpG-island methylation is the molecular engine that drives the progression through sequential steps of the pathway, from hyperplastic polyp to a form of atypical hyperplastic polyp (termed sessile serrated adenoma) to dysplastic serrated polyp and, ultimately to serrated carcinoma.
  • Its endpoint is a colorectal carcinoma that is CIMP-low and MSS, and both the advanced serrated adenoma and carcinoma stages of this pathway show molecular genetic and morphologic features that overlap with those of the conventional APC carcinogenic pathway.
  • Clinical studies are needed to elucidate the natural history of serrated neoplasia, and provide evidence-based guidance for risk assessment and surveillance of individuals discovered to harbor its various serrated polyp precursors.

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  • (PMID = 17996799.001).
  • [ISSN] 0889-8553
  • [Journal-full-title] Gastroenterology clinics of North America
  • [ISO-abbreviation] Gastroenterol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 100
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27. Mittal K, Da Costa D: Endometrial hyperplasia and carcinoma in endometrial polyps: clinicopathologic and follow-up findings. Int J Gynecol Pathol; 2008 Jan;27(1):45-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 1) to evaluate findings in follow-up hysterectomy specimens after a diagnosis of complex atypical hyperplasia or carcinoma in endometrial polyps (EMPs) for possible significance in management strategies; and 2)to identify features in these polyps, that are predictive of the presence of endometrial hyperplasia or carcinoma in subsequent hysterectomy.
  • Of the 29 patients with complex atypical hyperplasia within the polyp, 19 out of 29 (66%) patients had hyperplasia of the non-polyp endometrium, and adenocarcinoma was observed in 9 out of 29 (31%) patients on follow-up hysterectomy.
  • The percentage of polyp area involved by the hyperplasia was predictive of finding endometrial disorder in subsequent hysterectomy (P = 0.005).
  • Of the 8 patients with adenocarcinoma in situ (AIS) within the polyp 3 (38%) had myoinvasive adenocarcinoma.
  • Eight of the nine cases with carcinoma in endometrial polyp had endometrial pathology on hysterectomy.
  • The above findings reinforce the need for hysterectomy especially in postmenopausal women with atypical complex hyperplasia or carcinoma in endometrial polyps even if these changes appear confined to the polyp in initial sampling.

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  • (PMID = 18156974.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Mossa B, Torcia F, Avenoso F, Tucci S, Marziani R: Occurrence of malignancy in endometrial polyps during postmenopause. Eur J Gynaecol Oncol; 2010;31(2):165-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To evaluate the occurrence of endometrial polyp malignancy in pre- and postmenopausal women with or without symptoms.
  • RESULTS: Histological findings of biopsies obtained by operative hysteroscopy confirmed the presence of a simple endometrial polyp in 179 cases, polyps with typical simple hyperplasia in 42 cases, polyps with typical complex hyperplasia in 24 cases, polyps with atypical complex hyperplasia in three cases; carcinomatous polyps in seven cases; atrophic polyps in 17 cases; functional polyps in 56 cases; and inadequate sample in 23 cases.
  • CONCLUSIONS: This study revealed that prevalence of endometrial polyp malignant transformation was < or = 2.84% in postmenopausal and symptomatic patients.

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  • (PMID = 20527232.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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29. Zhang H, Wang B, Liu R, Wen S, Huangfu H: [Effect of CDK2 on proliferation in laryngeal squamous cell carcinoma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Sep;22(18):824-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHOD: Fifty specimens of LSCC, twelve specimens of atypical hyperplasia and thirty specimens of vocal cord polyp were obtain during operation.
  • RESULT: The positive rate of CDK2 and gamma-tubulin in LSCC were 68.0% (34/50) and 78.0% (10/15), all of them were significant higher than those in the vocal cord polyp (P<0.05).

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  • (PMID = 19166026.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] EC 2.7.11.22 / CDK2 protein, human; EC 2.7.11.22 / Cyclin-Dependent Kinase 2
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30. Jiang Y, Chen Y, Gao L, Ye Q, Alonso MA: [Expression pattern of MAL in normal epithelial cells, benign tumor, and squamous cell carcinoma of larynx]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 May;23(10):451-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHOD: Use the immunohistochemical technique to analyze the distribution of MAL in normal laryngeal epithelial cells, polyp of vocal cords, laryngeal atypical hyperplasia and laryngeal squamous cell carcinoma.
  • RESULT: MAL-like immunohistochemical reactions are strongly expressed in normal laryngeal epithelial cells and its expression is no significantly different in epithelial cells of the polyp of vocal cords.
  • Comparatively, MAL expression is significantly down regulated in laryngeal atypical hyperplasia and laryngeal squamous cell carcinomas (P < 0.05).

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  • (PMID = 19670627.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / MAL protein, human; 0 / Membrane Transport Proteins; 0 / Myelin Proteins; 0 / Myelin and Lymphocyte-Associated Proteolipid Proteins; 0 / Proteolipids
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31. Jass JR: Serrated adenoma of the colorectum and the DNA-methylator phenotype. Nat Clin Pract Oncol; 2005 Aug;2(8):398-405
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  • HP and SA are related lesions and there is now strong evidence for a 'serrated-polyp pathway' to colorectal cancer (CRC) that is largely independent of the classic adenoma-to-carcinoma sequence.
  • A recently recognized lesion in this pathway is a HP variant characterized by relatively large size, atypical histology and proximal location in the colorectum.
  • Because this lesion lacks the traditional cytology of colorectal adenoma and in order to avoid confusion with SA, it is referred to in this review as sessile serrated polyp.
  • Subsets of colorectal cancers with an unusually high number of methylated CpG islands have been described as having the 'CpG-island-methylator phenotype' It is possible that many, if not all, CRCs with the CpG-island-methylator phenotype evolve through the serrated-polyp pathway that would, therefore, explain approximately 20% of all CRCs.

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  • (PMID = 16130936.001).
  • [ISSN] 1743-4254
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 63
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32. Lieng M, Qvigstad E, Sandvik L, Jørgensen H, Langebrekke A, Istre O: Hysteroscopic resection of symptomatic and asymptomatic endometrial polyps. J Minim Invasive Gynecol; 2007 Mar-Apr;14(2):189-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • STUDY OBJECTIVE: To estimate the occurrence of malignancy and atypical hyperplasia in endometrial polyps in patients with and without symptoms.
  • PATIENTS: All patients who underwent hysteroscopic resection of an endometrial polyp in our department from January 1, 2001 through March 1, 2005.
  • The prevalence of malignancy or atypical hyperplasia was 3.2% in women with symptoms and 3.9% in those without symptoms.
  • CONCLUSION: The prevalence of malignancy and atypical hyperplasia was found to be relatively high, indicating that symptomatic, as well as asymptomatic, endometrial polyps should be removed.

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  • (PMID = 17368255.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Yang LP, Yang ZL, Tan XG, Miao XY: [Expression of annexin A1 (ANXA1) and A2 (ANXA2) and its significance in benign and malignant lesions of gallbladder]. Zhonghua Zhong Liu Za Zhi; 2010 Aug;32(8):595-9
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  • OBJECTIVE: To study the expression levels of ANXA1 and ANXA2 and elucidate their clinicopathological significance in adenocarcinoma, peritumoral tissues, adenomatous polyp and chronic cholecystitis of gallbladder.
  • METHODS: EnVision(TM) immunohistochemical staining was used to detect the expression of ANXA1 and ANXA2 in paraffin-embedded tissue sections from resected specimens of adenocarcinoma (n = 108), peritumoral tissue (n = 46), adenomatous polyp (n = 15) and chronic cholecystitis (n = 35).
  • RESULTS: The positive rates and scores of ANXA1 and ANXA2 were significantly higher in adenocarcinoma (59.3%, 56.5%; 3.2 ± 0.9, 3.4 ± 0.8) than those in peritumoral tissues (34.8%, 1.1 ± 0.8, P < 0.01; 30.4%, 1.0 ± 0.8, P < 0.01), adenomatous polyp (26.7%, 0.9 ± 0.7, P < 0.05 or P < 0.01; 26.7%, 0.9 ± 0.8, P < 0.05 or P < 0.01) and chronic cholecystitis (17.1%, 0.7 ± 0.9, P < 0.01; 20.0%, 0.8 ± 0.8, P < 0.01).
  • The benign lesions with positive ANXA1 and/or ANXA2 expression showed mild to severe atypical hyperplasia of the gallbladder epithelium.

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  • (PMID = 21122411.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / ANXA2 protein, human; 0 / Annexin A1; 0 / Annexin A2
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34. Ferrazzi E, Zupi E, Leone FP, Savelli L, Omodei U, Moscarini M, Barbieri M, Cammareri G, Capobianco G, Cicinelli E, Coccia ME, Donarini G, Fiore S, Litta P, Sideri M, Solima E, Spazzini D, Testa AC, Vignali M: How often are endometrial polyps malignant in asymptomatic postmenopausal women? A multicenter study. Am J Obstet Gynecol; 2009 Mar;200(3):235.e1-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: One single case of stage 1 grade 1 endometrial carcinoma on a polyp with a mean diameter of 40 mm (0.1%) was observed in asymptomatic women.
  • The prevalence of atypical hyperplastic polyps was 1.2% in asymptomatic women (2.2% in symptomatic patients; P < .005).
  • At multivariate analysis, polyps' diameter was the only variable significantly associated to an abnormal histology (cancer, polypoid cancer, and atypical hyperplasia) in asymptomatic women (odds ratio for polyps with mean diameter > 18 mm, 6.9; confidence interval, 2.2-21.4).
  • CONCLUSION: Follow-up and/or treatment of endometrial polyps incidentally diagnosed in asymptomatic postmenopausal patients could be safely restricted to few selected cases based on polyp diameter.

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  • (PMID = 19027096.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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35. Rousková B, Kuklová P, Skába R, Frantlová M: [Rates and histological characteristics of rectal polyps in childhood]. Rozhl Chir; 2006 Oct;85(10):501-3
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  • Histological examination showed a juvenile polyp in 15 (75%) patients, atypical juvenile polyp and inflammatory polyp in 2 patients each and lymphoid polyp in one case.

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  • (PMID = 17233176.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
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36. Heron DE, Axtel A, Gerszten K, Amortegui A, Kelley J, Comerci J, Edwards RP: Villoglandular adenocarcinoma of the cervix recurrent in an episiotomy scar: a case report in a 32-year-old female. Int J Gynecol Cancer; 2005 Mar-Apr;15(2):366-71
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  • A prenatal smear in December 1996 revealed atypical glandular cells of undetermined significance.
  • A sterile speculum exam in April 1997 at 31-week gestational age revealed a polyp on the anterior lip of the cervix, pathology consistent with a well-differentiated villoglandular adenocarcinoma.

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  • (PMID = 15823127.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Garuti G, Cellani F, Centinaio G, Sita G, Nalli G, Luerti M: Histopathologic behavior of endometrial hyperplasia during tamoxifen therapy for breast cancer. Gynecol Oncol; 2006 May;101(2):269-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Two patients showing complex atypical hyperplasia underwent vaginal hysterectomy, whereas the remaining 24 patients, suffering from endometrial hyperplasia without atypia, were followed on a yearly basis during the period of tamoxifen intake, by hysteroscopy and endometrial biopsy.
  • Progression from complex hyperplasia to complex atypical hyperplasia (1 patient) and from complex and simple hyperplasia to adenocarcinomas (2 patients) was found within 24 months of tamoxifen intake in 3 patients (12.5%).
  • In 13 patients (54.1%), stable histology of simple or complex hyperplasia was found, whereas 6 patients (25.0%), with focal hyperplasia harbored in an endometrial polyp, showed a normalization of endometrial histology after polyp resection.
  • CONCLUSIONS: Endometrial hyperplasias without atypia diagnosed before endocrine therapy for breast cancer in menopausal patients show an early and high progression-rate to atypical lesions under tamoxifen influence.

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  • (PMID = 16297970.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 094ZI81Y45 / Tamoxifen
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38. Xu CZ, Dong P, Li XY, Zhang ZJ: [Expression and clinical significance of hypoxia-inducible factor-1alpha and cyclooxygenase-2 in laryngeal squamous cell carcinoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Jan;44(1):57-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • As control group, 15 cases of atypical hyperplasia, 10 cases of leukoplakia of vocal cord and 10 cases of polyp of vocal cord were studied.
  • The positive expressions in LSCC were significantly higher than those in atypical hyperplasia, leukoplakia and polyp of vocal cord ( Fisher's exact test, P < 0.01).

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  • (PMID = 19484991.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Hypoxia-Inducible Factor 1, alpha Subunit; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human
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39. [Prevalence and characteristics of endometrial polyps in patients with abnormal uterine bleeding]. Vojnosanit Pregl; 2008 May;65(5):349-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Regarding histopathological features of EPs (presence of atypical hyperplasia or endometrial carcinoma), patients were divided into two groups: group A--patients who had EPs and EPs with hyperplasia without atypia (n = 204) and group B--patients who had EPs with atypical hyperplasia and EPs with carcinoma (n = 7).
  • Histopathologically, there were 175 (82.94%) EPs, 29 (13.74%) EPs with hyperplasia without atypia, 5 (2.37%) EPs with atypical hyperplasia, and 2 (0.95%) EPs with endometrial carcinoma.
  • Contrary to the patients with EPs and EPs with hyperplasia without atypia (group A), patients who had EPs with atypical hyperplasia and EPs with carcinoma (group B) were older (p < 0.05), and more commonly postmenopausal (p < 0.05) and with hypertension (p < 0.05), all of statistical significance.
  • Atypical hyperplasia and endometrial carcinoma were rarely confined to a polyp.

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  • (PMID = 18630127.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia
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40. Zaballos P, Rodero J, Serrano P, Cuellar F, Guionnet N, Vives JM: Pyogenic granuloma clinically and dermoscopically mimicking pigmented melanoma. Dermatol Online J; 2009;15(10):10
MedlinePlus Health Information. consumer health - Skin Conditions.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pyogenic granuloma is a common, benign, acquired, vascular growth of skin and mucous membranes that usually presents as a solitary, rapidly, growing, papule or polyp that bleeds easily after minor trauma.
  • Dermoscopic evaluation revealed the presence of a blue-white veil, a black blotch, polymorphous atypical vessels, milky-red areas, and hemorrhagic crusts.

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  • (PMID = 19951628.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Wang LP, Yang GZ, Li L, Zhou ZY, Gao BL, Wang B, Han Y: [Clinicopathological and immunohistochemical features of colorectal sessile serrated adenoma]. Zhonghua Zhong Liu Za Zhi; 2009 Apr;31(4):269-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The clinicopathological data of 11 cases of SSA, 51 cases of hyperplastic polyp (HP) and one case with mixed HP/SSA were reviewed and analyzed retrospectively.
  • RESULTS: The major histological features in SSA were architectural abnormality in crypts, dilatation of serrated crypt bases like an inverted "T" or "L" shape adjacent to muscularis mucosa.
  • Atypical cells containing round to oval nuclei and nucleoli were also observed.
  • CONCLUSION: Morphological diagnosis of SSA was mainly based on crypt architectural and cellular abnormalities, and the crypt architectural abnormality may be more important than cellular features.

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  • (PMID = 19615281.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Homeodomain Proteins; 0 / Keratin-7; 0 / Ki-67 Antigen; 0 / Trans-Activators; 0 / Tumor Suppressor Protein p53; 156560-97-3 / Cdx-2-3 protein
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42. Golan A, Cohen-Sahar B, Keidar R, Condrea A, Ginath S, Sagiv R: Endometrial polyps: symptomatology, menopausal status and malignancy. Gynecol Obstet Invest; 2010;70(2):107-12
MedlinePlus Health Information. consumer health - Menopause.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pathologic evaluation disclosed 7 cases of malignancy and 4 cases of atypical hyperplasia among bleeding postmenopausal women (11/263, 4%) and 2 malignancies and 3 cases of hyperplasia with atypia among asymptomatic postmenopausal women (5/378, 1.3%).
  • We recommend removal of any verified endometrial polyp.

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  • [Copyright] Copyright 2010 S. Karger AG, Basel.
  • (PMID = 20332644.001).
  • [ISSN] 1423-002X
  • [Journal-full-title] Gynecologic and obstetric investigation
  • [ISO-abbreviation] Gynecol. Obstet. Invest.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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43. Chin N, Platt AB, Nuovo GJ: Squamous intraepithelial lesions arising in benign endocervical polyps: a report of 9 cases with correlation to the Pap smears, HPV analysis, and immunoprofile. Int J Gynecol Pathol; 2008 Oct;27(4):582-90
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The reported incidence of squamous intraepithelial lesion (SIL) occurring in an endocervical polyp is typically less than 1/1,000 (0.1%).
  • There were 12 Pap smears (either concurrent or from 6 mo to 2 yr before the biopsy-proven SIL) taken from the 9 women and most (10/12%-83%) were diagnosed as normal (7), atypical squamous cells of undetermined significance (ASCUS), favor reactive changes (1), or ASCUS (2) whereas the other 2 (17%) smears were diagnosed as low-grade SIL.

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  • [CommentIn] Int J Gynecol Pathol. 2009 Nov;28(6):567; author reply 567 [19851207.001]
  • (PMID = 18753960.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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44. Ozdemir S, Celik C, Gezginç K, Kıreşi D, Esen H: Evaluation of endometrial thickness with transvaginal ultrasonography and histopathology in premenopausal women with abnormal vaginal bleeding. Arch Gynecol Obstet; 2010 Oct;282(4):395-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The abnormal endometrium was composed of 11.8% hyperplasia (simple + atypical complex), 4.2% endometrial polyp, and 5.5% adenocarcinoma.

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  • (PMID = 19921229.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Germany
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45. Hamatani S, Wada R, Morita A, Hasegawa C, Mitsuda A, Hatori T, Nonaka H, Takahashi K, Gomi S, Shibuya K: Cellular kinetics and K-ras codon 12 mutations according to histomorphometric type of colorectal polyps with epithelial serrated proliferation. Oncol Rep; 2005 Jul;14(1):121-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histomorphologically, type 3 CP-ESP is considered an atypical hyperplastic polyp, occasionally associated with an elongated proliferation zone or K-ras mutations.

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  • (PMID = 15944778.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Codon; 0 / Ki-67 Antigen
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46. Daum O, Hatlova J, Mandys V, Grossmann P, Mukensnabl P, Benes Z, Michal M: Comparison of morphological, immunohistochemical, and molecular genetic features of inflammatory fibroid polyps (Vanek's tumors). Virchows Arch; 2010 May;456(5):491-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Vanek's tumor (inflammatory fibroid polyp) is a rare benign lesion occurring throughout the digestive tract.
  • Atypical, inflammatory pseudotumor-like Vanek's tumor lacks concentric formations and is CD34 negative.

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  • (PMID = 20393746.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
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47. Baichi MM, Arifuddin RM, Mantry PS: Small-bowel masses found and missed on capsule endoscopy for obscure bleeding. Scand J Gastroenterol; 2007 Sep;42(9):1127-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Benign lesions included inflammatory fibroid polyp (n=1) and lipoma (n=1).
  • Tumors can have an atypical appearance including focal ulceration, nodularity, or active bleeding without a clear lesion.

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  • (PMID = 17710681.001).
  • [ISSN] 0036-5521
  • [Journal-full-title] Scandinavian journal of gastroenterology
  • [ISO-abbreviation] Scand. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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48. Timmermans A, van Doorn LC, Opmeer BC, Kroeks MV, Duk MJ, Bouwmeester AM, Kruitwagen RF, Dijkhuizen FP, Mol BW, Dutch Study in Postmenopausal Bleeding (DUPOMEB): Follow-up of women after a first episode of postmenopausal bleeding and endometrial thickness greater than 4 millimeters. Obstet Gynecol; 2008 Jan;111(1):137-43

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There was no difference with respect to recurrence rate between patients with polyp removal, patients with a normal hysteroscopy, and patients with office endometrial sampling alone at the initial workup.
  • Two patients were diagnosed with atypical endometrial hyperplasia upon recurrent bleeding.
  • This recurrence rate is not related to incorporation of hysteroscopy or polyp removal at the initial workup.

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  • [CommentIn] Obstet Gynecol. 2008 Aug;112(2 Pt 1):379; author reply 379-80 [18669739.001]
  • (PMID = 18165402.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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49. Wang J, Wang H, Tang G, Hou Z, Wang G: Transitional cell carcinoma of upper urinary tract vs. benign lesions: distinctive MSCT features. Abdom Imaging; 2009 Jan-Feb;34(1):94-106
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These lesions include endometriosis, nephrogenic adenoma, mycetomas, malacoplakia, and inflammatory pseudotumor which are similar to infiltrating papillary TCCs; complex urolithiasis, passed stone of ureter and ureteropelvic junction, chronic ureteropelvic junction obstruction with superimposed infection, atypical pyelonephritis, and tuberculosis which mimic diffusely infiltrating TCCs, and fibroepithelial polyp which has the same CT appearances as papillary TCCs.

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  • (PMID = 18581162.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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50. Hideyama T, Tanaka H, Uesaka Y, Kunimoto M, Miwa A: [Case of primary intraocular central nervous system lymphoma with high interleukin 10 level and positive cytology in cerebrospinal fluid]. Rinsho Shinkeigaku; 2008 Jun;48(6):415-8
MedlinePlus Health Information. consumer health - Eye Care.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 73-year-old woman was admitted to the surgical department of our hospital for endoscopic resection of a colonic polyp.
  • Cytology of the cerebrospinal fluid was repeatedly examined, eventually revealing atypical lymphocytes with hyperlobulated nuclei and clear nucleoli.

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  • (PMID = 18616153.001).
  • [ISSN] 0009-918X
  • [Journal-full-title] Rinshō shinkeigaku = Clinical neurology
  • [ISO-abbreviation] Rinsho Shinkeigaku
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 130068-27-8 / Interleukin-10
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51. Lu JB, Li XQ, Zhu XZ: [Distinction between lymphoma-like lesions and lymphoma of uterine cervix: a clinicopathologic study of 26 cases]. Zhonghua Bing Li Xue Za Zhi; 2007 May;36(5):297-301
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The lesion generally presented with cervical erosion or polyp.
  • The former was characterized by a diffuse monomorphic population of large atypical lymphoid cells, while neoplastic follicles were identified in the latter.

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  • (PMID = 17706135.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD79; 0 / CD79A protein, human; 0 / Immunoglobulin G
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52. Tahlan A, Nanda A, Mohan H: Uterine adenomyoma: a clinicopathologic review of 26 cases and a review of the literature. Int J Gynecol Pathol; 2006 Oct;25(4):361-5
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It may be located within the myometrium, or it may involve or originate in the endometrium and grow as a polyp.
  • Adenomyomas have to be distinguished from a number of other lesions, for example, adenomyosis, leiomyoma with entrapped glands, atypical polypoid adenomyoma, endometrial polyps, adenofibroma, and adenosarcoma.

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  • (PMID = 16990713.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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53. Vesna A, Neli B: Benefit and safety of 28-day transdermal estrogen regimen during vaginal hysterectomy (a controlled trial). Maturitas; 2006 Feb 20;53(3):282-98
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There were no significant differences in occurrence of more thickened endometrium and more significant morphological changes (endometrial polyp, simplex hyperplasia) between the groups.
  • In none of the patients from the both study groups complex hyperplasia, atypical hyperplasia or endometrial carcinoma were observed.

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  • (PMID = 16011883.001).
  • [ISSN] 0378-5122
  • [Journal-full-title] Maturitas
  • [ISO-abbreviation] Maturitas
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Estrogens, Conjugated (USP); 4TI98Z838E / Estradiol
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54. Garuti G, Cellani F, Centinaio G, Montanari G, Nalli G, Luerti M: Prospective endometrial assessment of breast cancer patients treated with third generation aromatase inhibitors. Gynecol Oncol; 2006 Nov;103(2):599-603
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In 3 patients, the abnormality consisted of simple hyperplasias and in all these patients an abnormal endometrium (1 complex atypical hyperplasia and 2 simple hyperplasias) was already detected at baseline assessment.
  • Only in 1 patient (2.2%) of group 2 did we find an emerging pathology, consisting of adenosarcoma harbored within an endometrial polyp, detected after 12 months of therapy with letrozole.
  • In 3 out of 5 patients showing simple hyperplasia and in 1 patient showing atypical hyperplasia before the start of AIs therapy, we observed a reversal to normal endometrium and to simple hyperplasia, respectively, after 12 months of therapy with anastrozole.

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  • (PMID = 16750259.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aromatase Inhibitors; 094ZI81Y45 / Tamoxifen
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55. Umeda I, Kanisawa Y, Ohta H, Nobuoka A, Doi T, Watanabe N, Iwai K, Kawasaki R: [Fever: an atypical manifestation of gastric inflammatory fibroid polyp]. Nihon Naika Gakkai Zasshi; 2006 Aug 10;95(8):1551-3
MedlinePlus Health Information. consumer health - Stomach Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Fever: an atypical manifestation of gastric inflammatory fibroid polyp].

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  • (PMID = 16955942.001).
  • [ISSN] 0021-5384
  • [Journal-full-title] Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine
  • [ISO-abbreviation] Nippon Naika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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56. Samarasam I, Roberts-Thomson J, Brockwell D: Two atypical presentations of a caecal polyp. ANZ J Surg; 2009 Oct;79(10):765-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Two atypical presentations of a caecal polyp.

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  • (PMID = 19878186.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Australia
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57. Zaffiri L, d'Ettorre G, Massetti AP, Mascellino MT, Mastroianni CM, Vullo V: Atypical localization of Leishmaniasis in an intestinal polyp. Infection; 2008 Mar;36(2):187-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical localization of Leishmaniasis in an intestinal polyp.

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  • (PMID = 18327682.001).
  • [ISSN] 0300-8126
  • [Journal-full-title] Infection
  • [ISO-abbreviation] Infection
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antiprotozoal Agents; 7XU7A7DROE / Amphotericin B
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