[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 246
76. Tommaso CL: PCI for LMCA stenosis--is it time to ride the rank bull? Catheter Cardiovasc Interv; 2006 Sep;68(3):363-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] PCI for LMCA stenosis--is it time to ride the rank bull?

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16894577.001).
  • [ISSN] 1522-1946
  • [Journal-full-title] Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
  • [ISO-abbreviation] Catheter Cardiovasc Interv
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Coated Materials, Biocompatible
  •  go-up   go-down


77. Breccia M, Biondo F, Latagliata R, Carmosino I, Mandelli F, Alimena G: Identification of risk factors in atypical chronic myeloid leukemia. Haematologica; 2006 Nov;91(11):1566-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification of risk factors in atypical chronic myeloid leukemia.
  • In the WHO classification atypical chronic myeloid leukemia (CML) has been considered as a new distinct clinical entity included in the category of mixed myeloproliferative/myelodysplastic disorders.
  • Little is known about this uncommon disease, whose incidence is about of one-two cases every 100 cases of Ph-positive CML.
  • We analyzed our series of 55 patients diagnosed as having aCML, with the aim of identifying clinical factors of possible prognostic value on survival and acute transformation.
  • [MeSH-major] Leukemia, Myelogenous, Chronic, BCR-ABL Positive / diagnosis


78. Park SJ, Kim YH: Percutaneous coronary intervention for unprotected left main coronary artery stenosis. Cardiol Clin; 2010 Feb;28(1):81-95
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Percutaneous coronary intervention for unprotected left main coronary artery stenosis.
  • Because of the long-term benefit of coronary artery bypass graft (CABG) surgery in medical therapy, CABG has been the standard treatment of unprotected left main coronary artery (LMCA) stenosis.
  • However, with the advancement of techniques and equipment, the percutaneous interventional approach for implantation of coronary stents has been shown to be feasible for patients with unprotected LMCA stenosis.
  • [MeSH-major] Angioplasty, Balloon, Coronary. Coronary Artery Disease / therapy. Coronary Stenosis / therapy

  • MedlinePlus Health Information. consumer health - Coronary Artery Disease.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19962051.001).
  • [ISSN] 1558-2264
  • [Journal-full-title] Cardiology clinics
  • [ISO-abbreviation] Cardiol Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 69
  •  go-up   go-down


79. Martínez-Ríos MA, Méndez-Ortíz A, Gaspar J, Barragán-García R, Fernández-de-la-Reguera G, González-Quesada CJ: Left main coronary artery stenosis treatment with two paclitaxel-eluting stents in a patient with cardiac allograft vasculopathy. Arch Cardiol Mex; 2008 Oct-Dec;78(4):407-12
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Left main coronary artery stenosis treatment with two paclitaxel-eluting stents in a patient with cardiac allograft vasculopathy.
  • After the first year of transplantation, allograft coronary artery disease (ACAD) is the second main cause of death.
  • We present a case of successful stenting of the left main coronary artery (LMCA) in a patient with ACAD.
  • Coronary angiogram showed a severe stenosis in the proximal segment of the LMCA; we performed stenting with a paclitaxel-eluting stent (PES).
  • Our report suggests the efficacy of PES as ACAD treatment of the unprotected LMCA.

  • MedlinePlus Health Information. consumer health - Heart Transplantation.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. TAXOL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19205549.001).
  • [ISSN] 1405-9940
  • [Journal-full-title] Archivos de cardiología de México
  • [ISO-abbreviation] Arch Cardiol Mex
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Mexico
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
  •  go-up   go-down


80. Hsu JT, Chu CM, Chang ST, Kao CL, Chung CM: Percutaneous coronary intervention versus coronary artery bypass graft surgery for the treatment of unprotected left main coronary artery stenosis: in-hospital and one year outcome after emergent and elective treatments. Int Heart J; 2008 May;49(3):355-70
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Percutaneous coronary intervention versus coronary artery bypass graft surgery for the treatment of unprotected left main coronary artery stenosis: in-hospital and one year outcome after emergent and elective treatments.
  • This study attempts to compare the risks and benefits of provisional stenting with drug eluting stents and bypass surgery for left main coronary artery (LMCA) stenosis.
  • Recent improvements in interventional technologies have increased interest in percutaneous treatment of LMCA stenosis.
  • However, application of percutaneous techniques to LMCA has been sporadic and controversial.
  • In-hospital and one year outcomes of coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) cases were compared.
  • From September, 2003 to June, 2005, a total of 59 consecutive patients with de novo unprotected LMCA stenosis were treated with either CABG or PCI.
  • Twenty patients received non-intravascular ultrasound-guided PCI with a stent in the LMCA.
  • At 30-day follow-up, the major adverse cardiac and cerebrovascular event (MACE) rates of mortality, myocardial infarction, cerebral vascular accident, and target vessel revascularization were 25.6% in the CABG group and 5% in the PCI group (P=0.054).
  • [MeSH-major] Angioplasty, Balloon, Coronary. Coronary Artery Bypass. Coronary Stenosis / therapy

  • MedlinePlus Health Information. consumer health - Coronary Artery Bypass Surgery.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18612192.001).
  • [ISSN] 1349-2365
  • [Journal-full-title] International heart journal
  • [ISO-abbreviation] Int Heart J
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


81. Vaseghi M, Lee MS, Currier J, Tobis J, Shapiro S, Aboulhosn J: Percutaneous intervention of left main coronary artery compression by pulmonary artery aneurysm. Catheter Cardiovasc Interv; 2010 Sep 1;76(3):352-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Percutaneous intervention of left main coronary artery compression by pulmonary artery aneurysm.
  • BACKGROUND: Extrinsic compression of the left main coronary artery (LMCA) by a pulmonary artery aneurysm (PAA) has become increasingly recognized as an etiology of angina in patients with pulmonary arterial hypertension (PAH).
  • The purpose of this study was to assess the feasibility and efficacy of LMCA stenting in the treatment LMCA stenosis because of PAA.
  • METHODS: Retrospective analysis of data on patients with PAH who presented with angina and underwent percutaneous intervention of their LMCA compression because of PAA was performed.
  • RESULTS: Five patients (age 51 ± 16 years, all female) with PAH presented with angina and underwent LMCA stenting between 2007 and 2009.
  • LMCA compression because of a PAA was diagnosed in all patients with cardiac CT angiography after echocardiography demonstrated an enlarged pulmonary artery.
  • LMCA stenting was successfully performed in all patients with resolution of angina and electrocardiographic abnormalities.
  • CONCLUSIONS: LMCA stenting appears to be a feasible and durable option in patients who present with angina because of compression by PAA.
  • [MeSH-major] Aneurysm / etiology. Angioplasty, Balloon, Coronary. Coronary Stenosis / therapy. Hypertension, Pulmonary / complications. Pulmonary Artery

  • Genetic Alliance. consumer health - Coronary Artery Aneurysm.
  • MedlinePlus Health Information. consumer health - Aneurysms.
  • MedlinePlus Health Information. consumer health - Pulmonary Hypertension.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Catheter Cardiovasc Interv. 2010 Sep 1;76(3):357-8 [20839347.001]
  • (PMID = 20552652.001).
  • [ISSN] 1522-726X
  • [Journal-full-title] Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
  • [ISO-abbreviation] Catheter Cardiovasc Interv
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


82. Murasato Y: Impact of three-dimensional characteristics of the left main coronary artery bifurcation on outcome of crush stenting. Catheter Cardiovasc Interv; 2007 Feb 1;69(2):248-56
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of three-dimensional characteristics of the left main coronary artery bifurcation on outcome of crush stenting.
  • BACKGROUND: Crush stenting with drug-eluting stents is used to treat left main coronary artery (LMCA) bifurcations.
  • However, the rate of restenosis at the left circumflex (LCX) artery ostium is high.
  • The impact of the three-dimensional (3D) structure of LMCA bifurcation on the outcome of crush stenting with respect to restenosis has not been described.
  • OBJECTIVES: This study examined the stent expansion, deformity, overlapping, and apposition after crush stenting of LMCA bifurcations.
  • METHODS: Bare metal stents were crushed at LMCA bifurcations in a 3D model that reproduced actual angles, such that the stent deployed from the LMCA to the left anterior descending (LAD) artery crushed the stent deployed from the LMCA to the LCX, followed by kissing balloon inflation.
  • RESULTS: In the 3D model, one stent overlapped the other in the distal LMCA, in contrast to the nearly parallel position of the stents observed in a separate two-dimensional model.
  • A narrow LMCA-LCX angle was associated with less expansion of the LCX stent at the ostium than more distally, and with a higher likelihood of incomplete stent apposition.
  • CONCLUSIONS: Overlap of the LAD stent over, as opposed to under, the LCX stent was associated with close apposition of the stent to the vessel on the myocardial side, at the ostium of the LCX artery, where atherosclerotic plaques are likely to be present.
  • The spatial plaque burden and bifurcation angle should be closely examined before crush stenting, and segments should not be left unstented over large plaques.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2006 Wiley-Liss, Inc.
  • (PMID = 17211894.001).
  • [ISSN] 1522-1946
  • [Journal-full-title] Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
  • [ISO-abbreviation] Catheter Cardiovasc Interv
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


83. Tang HC, Wong A, Wong P, Chua TS, Koh TH, Lim ST: Clinical features and outcome of emergency percutaneous intervention of left main coronary artery occlusion in acute myocardial infarction. Singapore Med J; 2007 Dec;48(12):1122-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical features and outcome of emergency percutaneous intervention of left main coronary artery occlusion in acute myocardial infarction.
  • INTRODUCTION: Acute myocardial infarction (AMI) due to left main coronary artery (LMCA) occlusion carries a grave prognosis.
  • Large series reporting on the outcome of emergency revascularisation (percutaneous or surgical) of acute LMCA occlusion have been scarce.
  • 11 patients (0.8 percent) underwent percutaneous intervention to the LMCA.
  • The remaining one had angioplasty and stenting to the left main artery.
  • CONCLUSION: Percutaneous revascularisation of acute LMCA occlusion is feasible and the best outcome is seen in stable patients.
  • [MeSH-minor] Acute Disease. Adult. Aged. Cohort Studies. Coronary Angiography. Emergency Treatment. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Risk Factors. Severity of Illness Index. Singapore. Stents. Survival Rate. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Heart Attack.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18043840.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
  •  go-up   go-down


8
Advertisement
4. Leslie-Mazwi TM, Avery LL, Sims JR: Intra-arterial air thrombogenesis after cerebral air embolism complicating lower extremity sclerotherapy. Neurocrit Care; 2009;11(2):247-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intra-arterial air thrombogenesis after cerebral air embolism complicating lower extremity sclerotherapy.
  • BACKGROUND: Cerebral arterial gas embolism is a potentially life-threatening event.
  • Sclerotherapy is an extremely rare cause of cerebral arterial gas embolism.
  • METHOD: Case-report RESULTS: A 38-year-old female suffered acute onset of a left middle cerebral artery (LMCA) syndrome with an NIH stroke score of 11 approximately 10 min after lower extremity sclerotherapy.
  • CT angiogram demonstrated LMCA intraarterial air.
  • [MeSH-minor] Adult. Female. Humans. Hyperbaric Oxygenation. Intracranial Embolism / diagnostic imaging. Intracranial Embolism / etiology. Intracranial Embolism / therapy. Middle Cerebral Artery / diagnostic imaging. Sclerosing Solutions / adverse effects. Sclerosing Solutions / therapeutic use. Sclerotherapy / adverse effects. Sodium Tetradecyl Sulfate / adverse effects. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Embolism.
  • MedlinePlus Health Information. consumer health - Varicose Veins.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Anesthesiology. 1997 Mar;86(3):710-7 [9066338.001]
  • [Cites] Dermatol Surg. 2002 Jan;28(1):11-5 [11991262.001]
  • [Cites] Crit Care Med. 2005 Apr;33(4):841-6 [15818114.001]
  • [Cites] Stroke. 1996 Feb;27(2):303-9; discussion 310 [8571428.001]
  • [Cites] J Thorac Cardiovasc Surg. 2001 Jan;121(1):3-9 [11135155.001]
  • [Cites] Anesthesiology. 2004 Jan;100(1):77-84 [14695727.001]
  • [Cites] Circulation. 2003 Jan 7;107(1):5-9 [12515733.001]
  • [Cites] Ann Thorac Surg. 1995 Oct;60(4):1138-42 [7574975.001]
  • [Cites] N Engl J Med. 2008 Apr 3;358(14 ):1525-6 [18385510.001]
  • [Cites] Br J Exp Pathol. 1973 Apr;54(2):163-72 [4121722.001]
  • [Cites] Am J Prev Med. 1988 Mar-Apr;4(2):96-101 [3395496.001]
  • [Cites] Aerosp Med. 1972 Sep;43(9):946-53 [4116740.001]
  • [Cites] N Engl J Med. 2008 Aug 7;359(6):656-7; author reply 657 [18687653.001]
  • [Cites] Ann Thorac Surg. 1988 Feb;45(2):198-202 [3341824.001]
  • [Cites] Dermatol Surg. 2005 Feb;31(2):123-8; discussion 128 [15762201.001]
  • [Cites] Stroke. 1987 May-Jun;18(3):634-7 [3296333.001]
  • [Cites] N Engl J Med. 2000 Feb 17;342(7):476-82 [10675429.001]
  • [Cites] J Vasc Surg. 2006 Jan;43(1):162-4 [16414404.001]
  • (PMID = 19294535.001).
  • [ISSN] 1541-6933
  • [Journal-full-title] Neurocritical care
  • [ISO-abbreviation] Neurocrit Care
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Sclerosing Solutions; Q1SUG5KBD6 / Sodium Tetradecyl Sulfate
  •  go-up   go-down


85. Soulis JV, Giannoglou GD, Papaioannou V, Parcharidis GE, Louridas GE: Low-Density Lipoprotein concentration in the normal Left Coronary Artery tree. Biomed Eng Online; 2008;7:26
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low-Density Lipoprotein concentration in the normal Left Coronary Artery tree.
  • The resulted model includes the LMCA, LAD, LCxA and their main branches.
  • RESULTS: High concentration of LDL values appears at bifurcation opposite to the flow dividers in the proximal regions of the Left Coronary Artery (LCA) tree, where atherosclerosis frequently occurs.
  • For the high, median and low molecular diffusivities, the peak values of the normalized LDL luminal surface concentration at the LMCA bifurcation reach 1.065, 1.080 and 1.205, respectively.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Med Biol Eng Comput. 2002 Sep;40(5):576-87 [12452420.001]
  • [Cites] Ann Biomed Eng. 2006 Jul;34(7):1119-28 [16791491.001]
  • [Cites] Atherosclerosis. 1983 Feb;46(2):225-31 [6838702.001]
  • [Cites] Arch Pathol Lab Med. 1988 Oct;112(10):1018-31 [3052352.001]
  • [Cites] Circulation. 1988 Nov;78(5 Pt 1):1167-80 [3180376.001]
  • [Cites] Circulation. 1992 Jul;86(1):232-46 [1535570.001]
  • [Cites] Circ Res. 1993 Feb;72(2):239-45 [8418981.001]
  • [Cites] Biorheology. 1999;36(3):207-23 [10690269.001]
  • [Cites] J Biomech Eng. 2001 Feb;123(1):80-7 [11277306.001]
  • [Cites] J Biomech Eng. 2002 Feb;124(1):1-8 [11871594.001]
  • [Cites] Ann Biomed Eng. 2002 Apr;30(4):430-46 [12085996.001]
  • [Cites] Ann Biomed Eng. 2002 Apr;30(4):461-71 [12085998.001]
  • [Cites] Ann Biomed Eng. 2002 Jun;30(6):778-91 [12220078.001]
  • [Cites] Int J Cardiol. 2002 Nov;86(1):27-40 [12243848.001]
  • [Cites] Physiol Chem Phys Med NMR. 1992;24(4):307-12 [1296211.001]
  • [Cites] Med Eng Phys. 1996 Jun;18(4):326-32 [8963477.001]
  • [Cites] Atherosclerosis. 1996 Jun;123(1-2):1-15 [8782833.001]
  • [Cites] Ann N Y Acad Sci. 1998 Sep 11;858:137-46 [9917815.001]
  • [Cites] J Biomech. 2005 Apr;38(4):903-17 [15713312.001]
  • [Cites] J Biomech. 2006;39(4):742-9 [16439244.001]
  • [Cites] Angiology. 2006 Jan-Feb;57(1):33-40 [16444454.001]
  • [Cites] Atherosclerosis. 1977 Feb;26(2):181-94 [836354.001]
  • (PMID = 18925974.001).
  • [ISSN] 1475-925X
  • [Journal-full-title] Biomedical engineering online
  • [ISO-abbreviation] Biomed Eng Online
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Lipoproteins, LDL
  • [Other-IDs] NLM/ PMC2615017
  •  go-up   go-down


86. Park SJ, Park DW: Left main stenting: is it a different animal? EuroIntervention; 2010 Dec;6 Suppl J:J112-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Left main stenting: is it a different animal?
  • For several decades, coronary-artery bypass grafting (CABG) has been regarded as the treatment of choice for patients with unprotected left main coronary artery (LMCA) disease.
  • However, because of marked advancements in techniques of percutaneous coronary intervention (PCI) with stenting and CABG, as well as adjunctive pharmacologic therapy, a new evaluation and review of current indications for optimal revascularisation therapy for LMCA disease may be required to determine the standard of care for these patients.
  • The available current evidence suggests that the composite outcome of death, myocardial infarction and stroke is similar in patients with LMCA disease who are treated with PCI with stenting or CABG, the only difference was the rate of repeat revascularisation.
  • Although PCI can be performed successfully in most LMCA lesions, "high-risk" anatomic subsets, especially involving distal LMCA bifurcation lesions, continue to present unique technical challenges to interventional cardiologists, and, therefore, an integrated approach combing advanced devices, tailored techniques, adjunctive support of physiologic and morphologic evaluation, and adjunctive pharmacologic agents should be reinforced to improve clinical outcomes.
  • [MeSH-major] Angioplasty, Balloon, Coronary. Coronary Artery Disease / therapy. Stents

  • MedlinePlus Health Information. consumer health - Coronary Artery Disease.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21930474.001).
  • [ISSN] 1969-6213
  • [Journal-full-title] EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
  • [ISO-abbreviation] EuroIntervention
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Metals
  •  go-up   go-down


87. Fend F, Horn T, Koch I, Vela T, Orazi A: Atypical chronic myeloid leukemia as defined in the WHO classification is a JAK2 V617F negative neoplasm. Leuk Res; 2008 Dec;32(12):1931-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical chronic myeloid leukemia as defined in the WHO classification is a JAK2 V617F negative neoplasm.
  • Atypical chronic myeloid leukemia (aCML) as defined by the WHO classification is a rare hematopoietic stem cell disorder, which shows both myeloproliferative as well as myelodysplastic features.
  • Because of the presence of neutrophilic leukocytosis, aCML may resemble chronic myelogenous leukemia.
  • However, in contrast with the latter, aCML lacks a Philadelphia chromosome or the BCR/ABL fusion gene.
  • The molecular pathogenesis of aCML and its relationship to other myeloproliferative neoplasms is unknown.
  • Fifty-nine cases of Philadelphia (Ph) chromosome negative chronic myeloproliferative neoplasms (CMPN) and normal bone marrows (BM) served as controls.
  • None of the nine amplifiable cases of aCML and none of the normal BM controls showed a JAK2 V617F mutation, in contrast to 45/59 (76%) of the Ph chromosome negative CMPN cases.
  • Atypical CML should therefore be considered as a JAK2 negative chronic myeloid neoplasm that remains properly categorized, alongside chronic myelomonocytic leukemia and juvenile myelomonocytic leukemia, within the WHO group of myelodysplastic/myeloproliferative neoplasms.
  • [MeSH-major] Amino Acid Substitution. Janus Kinase 2 / genetics. Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / classification. Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / genetics
  • [MeSH-minor] Blast Crisis / blood. Blast Crisis / pathology. Blood Cell Count. Fusion Proteins, bcr-abl / genetics. Humans. Mastocytosis / pathology. Neutrophils / pathology. Philadelphia Chromosome. World Health Organization


88. Macdonald D, Cross NC: Chronic myeloproliferative disorders: the role of tyrosine kinases in pathogenesis, diagnosis and therapy. Pathobiology; 2007;74(2):81-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chronic myeloproliferative disorders: the role of tyrosine kinases in pathogenesis, diagnosis and therapy.
  • The term chronic myeloproliferative disorders was originally used by Damashek to describe the link amongst a group of acquired blood diseases.
  • These may be chromosomal translocations resulting in the creation of a fusion kinase gene, examples of which include ABL, FGFR, and PDGFR as seen in disorders CML, 8p11 myeloproliferative syndrome, atypical CML and chronic eosinophilic leukaemia.
  • This abnormality is seen in 30-97% of cases of MPD with the phenotype PV, ET or CIMF.
  • [MeSH-major] Gene Expression Regulation, Enzymologic. Gene Expression Regulation, Neoplastic. Hypereosinophilic Syndrome / diagnosis. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / diagnosis. Myeloproliferative Disorders / diagnosis. Myeloproliferative Disorders / therapy. Protein-Tyrosine Kinases / genetics
  • [MeSH-minor] Chronic Disease. Hematopoiesis / genetics. Humans. Janus Kinase 2 / genetics. Molecular Diagnostic Techniques. Mutant Chimeric Proteins / genetics. Oncogene Proteins, Fusion / genetics. Point Mutation. Polycythemia Vera / diagnosis. Polycythemia Vera / genetics. Polycythemia Vera / therapy. Primary Myelofibrosis / diagnosis. Primary Myelofibrosis / genetics. Primary Myelofibrosis / therapy. Receptor, Fibroblast Growth Factor, Type 1 / genetics. Receptor, Platelet-Derived Growth Factor alpha / genetics. Receptor, Platelet-Derived Growth Factor beta / genetics. Thrombocythemia, Essential / diagnosis. Thrombocythemia, Essential / genetics. Thrombocythemia, Essential / therapy. mRNA Cleavage and Polyadenylation Factors / genetics

  • Genetic Alliance. consumer health - Chronic Myeloproliferative Disorders.
  • MedlinePlus Health Information. consumer health - Chronic Myeloid Leukemia.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17587879.001).
  • [ISSN] 1015-2008
  • [Journal-full-title] Pathobiology : journal of immunopathology, molecular and cellular biology
  • [ISO-abbreviation] Pathobiology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / FIP1L1-PDGFRA fusion protein, human; 0 / Mutant Chimeric Proteins; 0 / Oncogene Proteins, Fusion; 0 / mRNA Cleavage and Polyadenylation Factors; EC 2.7.10.1 / FGFR1 protein, human; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 1; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor beta; EC 2.7.10.2 / JAK2 protein, human; EC 2.7.10.2 / Janus Kinase 2
  • [Number-of-references] 29
  •  go-up   go-down


89. Adhya AK, Ahluwalia J, Varma N, Das R, Varma S: Abnormal chromatin clumping in leucocytes of Ph positive chronic myeloid leukemia cases - extending the morphological spectrum. Indian J Pathol Microbiol; 2008 Oct-Dec;51(4):548-50
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abnormal chromatin clumping in leucocytes of Ph positive chronic myeloid leukemia cases - extending the morphological spectrum.
  • According to the recent World Health Organization (WHO) classification, it is categorized as a variant of atypical chronic myeloid leukemia (aCML) or Ph-negative CML.
  • Most of the cases reported in literature have been negative for the Ph chromosome or the BCR-ABL gene.
  • Till date, Ph positivity has been demonstrated in just one case.
  • We report two more Ph-positive CML cases with abnormal chromatin clumping in neutrophils.
  • These two unusual cases go on to extend the morphological spectrum of granulocytic changes seen in Ph-positive CML.
  • [MeSH-major] Chromatin / ultrastructure. Leukemia, Myeloid, Chronic-Phase / pathology. Neutrophils / pathology. Philadelphia Chromosome

  • Genetic Alliance. consumer health - Chronic Myeloid Leukemia.
  • Genetic Alliance. consumer health - Leukemia, Myeloid.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19008593.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Chromatin
  •  go-up   go-down


90. de Man K, Patterson M, Kiemeneij F: Bifurcation balloon for left main shock syndrome: facilitating the simultaneous percutaneous reperfusion of the LAD and circumflex. J Invasive Cardiol; 2006 Nov;18(11):E270-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bifurcation balloon for left main shock syndrome: facilitating the simultaneous percutaneous reperfusion of the LAD and circumflex.
  • Acute occlusion of the left main coronary artery frequently causes cardiogenic shock and, when this occurs with an initial TIMI 0 flow, has an extremely poor prognosis.
  • This case describes a distal LMCA occlusion, 2 weeks post-stenting of the proximal LAD and proximal Cx, where this strategy was successfully used as a bridge to surgery.
  • [MeSH-major] Angioplasty, Balloon, Coronary / adverse effects. Catheterization / methods. Coronary Artery Bypass / methods. Coronary Restenosis / surgery. Coronary Thrombosis / surgery. Stents / adverse effects
  • [MeSH-minor] Cardiac Catheterization. Coronary Vessels / physiopathology. Electrocardiography. Equipment Failure. Fatal Outcome. Humans. Male. Middle Aged. Myocardial Infarction / complications. Myocardial Infarction / diagnosis. Myocardial Infarction / therapy. Postoperative Complications. Retreatment. Risk Assessment. Shock, Cardiogenic / diagnosis. Shock, Cardiogenic / etiology. Shock, Cardiogenic / therapy

  • MedlinePlus Health Information. consumer health - Coronary Artery Bypass Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17090827.001).
  • [ISSN] 1557-2501
  • [Journal-full-title] The Journal of invasive cardiology
  • [ISO-abbreviation] J Invasive Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


91. Suter Y, Schoenenberger AW, Toggweiler S, Jamshidi P, Resink T, Erne P: Intravascular ultrasound-based left main coronary artery assessment: comparison between pullback from left anterior descending and circumflex arteries. J Invasive Cardiol; 2009 Sep;21(9):457-60
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intravascular ultrasound-based left main coronary artery assessment: comparison between pullback from left anterior descending and circumflex arteries.
  • OBJECTIVE: We compared continuous pullback from the left anterior descending artery (LAD) with pullback from the circumflex artery (CX) for the assessment of the left main coronary artery (LMCA) by intravascular ultrasound (IVUS).
  • BACKGROUND: Gray-scale IVUS and virtual histology by IVUS (IVUS-VH) overcome many shortcomings of contrast angiography in diagnostic assessment of the LMCA.
  • METHODS: LMCA morphology was assessed by IVUS in 65 patients referred for elective or rescue coronary angiography.
  • The IVUS-determined degree of stenosis in the LMCA was a mean of 30% +/- 8% (range 15-52%).
  • CONCLUSIONS: Overall, there was excellent reliability between IVUS-based LMCA morphology assessment using pullback from either the LAD or the CX.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Invasive Cardiol. 2009 Sep;21(9):461-2 [19726819.001]
  • (PMID = 19726818.001).
  • [ISSN] 1557-2501
  • [Journal-full-title] The Journal of invasive cardiology
  • [ISO-abbreviation] J Invasive Cardiol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


92. Perreas KG, Dimitriou S, Ntalarizou E, Kalogris P, Amanatidis G, Khoury M, Karatassakis G, Michalis A: Left ostial stenosis surgical angioplasty. Thorac Cardiovasc Surg; 2007 Oct;55(7):424-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Left ostial stenosis surgical angioplasty.
  • BACKGROUND: Left main coronary stenosis, including ostial lesions, is conventionally treated by coronary bypass surgery.
  • Direct surgical reconstruction of the LMCA has been described and theoretically avoids these potential drawbacks.
  • METHODS: From May 1995 until December 2005, 25 patients with ostial left main stenosis underwent surgical angioplasty in our unit.
  • The left main coronary stem was approached anteriorly in all patients.
  • TOE demonstrated a wide open left main coronary artery normal flow pattern, and no aneurysmal dilatation or calcification of the onlay patch in 24 patients.
  • CONCLUSION: Surgical reconstruction of the LMCA is a safe and effective treatment for left main stenosis.
  • Re-institution of normal blood flow through the left main coronary artery possibly confers advantages over bypass surgery.

  • MedlinePlus Health Information. consumer health - Angioplasty.
  • MedlinePlus Health Information. consumer health - Heart Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17902063.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


93. de Jesus Perez VA, Haddad F, Vagelos RH, Fearon W, Feinstein J, Zamanian RT: Angina associated with left main coronary artery compression in pulmonary hypertension. J Heart Lung Transplant; 2009 May;28(5):527-30
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angina associated with left main coronary artery compression in pulmonary hypertension.
  • Left main coronary artery (LMCA) compression by an enlarged pulmonary artery trunk (PAT) has been associated with angina, but appropriate diagnostic and treatment approaches remain poorly defined.
  • We present two cases of angina caused by LMCA compression from an enlarged pulmonary artery, one of which also presented with new, severe left ventricular systolic dysfunction attributed to myocardial ischemia.
  • Diagnosis of LMCA stenosis was made via coronary angiography followed by computed tomography-gated coronary angiography (CT-CA), which confirmed pulmonary artery enlargement as the source of extrinsic compression.
  • Restoring LMCA patency with percutaneous intervention and/or aggressive treatment of pulmonary hypertension led to significant improvement in angina, cardiac function and quality of life.
  • Given the negative impact on cardiac function, prompt diagnosis and treatment of extrinsic LMCA compression should be considered a priority.
  • [MeSH-major] Angina Pectoris / etiology. Coronary Stenosis / etiology. Hypertension, Pulmonary / complications. Pulmonary Artery
  • [MeSH-minor] Adult. Angioplasty, Balloon, Coronary. Coronary Angiography. Echocardiography. Epoprostenol / therapeutic use. Humans. Male. Middle Aged. Myocardial Ischemia / diagnosis. Myocardial Ischemia / etiology. Myocardial Ischemia / therapy. Piperazines / therapeutic use. Purines / therapeutic use. Sildenafil Citrate. Stents. Sulfones / therapeutic use. Tomography, X-Ray Computed. Ultrasonography, Interventional. Vasodilator Agents / therapeutic use

  • Genetic Alliance. consumer health - Pulmonary Hypertension.
  • MedlinePlus Health Information. consumer health - Angina.
  • MedlinePlus Health Information. consumer health - Pulmonary Hypertension.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. SILDENAFIL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19416787.001).
  • [ISSN] 1557-3117
  • [Journal-full-title] The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
  • [ISO-abbreviation] J. Heart Lung Transplant.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Piperazines; 0 / Purines; 0 / Sulfones; 0 / Vasodilator Agents; BW9B0ZE037 / Sildenafil Citrate; DCR9Z582X0 / Epoprostenol
  •  go-up   go-down


94. Jönsson A, Hammar N, Nordquist T, Ivert T: Left main coronary artery stenosis no longer a risk factor for early and late death after coronary artery bypass surgery--an experience covering three decades. Eur J Cardiothorac Surg; 2006 Aug;30(2):311-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Left main coronary artery stenosis no longer a risk factor for early and late death after coronary artery bypass surgery--an experience covering three decades.
  • OBJECTIVE: To analyse early and late mortality after coronary artery bypass grafting (CABG) in patients with and without left main coronary artery (LMCA) stenosis during the 30-year period 1970-1999.
  • METHODS: A total of 1888 of 10,647 patients (18%) who underwent a first isolated CABG at the Karolinska Hospital in Stockholm, Sweden, during 1970-1999 had significant left main coronary artery stenosis.
  • RESULTS: The proportion of patients with LMCA stenosis of all CABG patients increased from 7% during the 1970s to 26% in 1999.
  • During 1970-1984 early mortality was 5.8% in patients with LMCA stenosis compared with 1.5% in patients without LMCA stenosis (odds ratio (OR) 3.7 (95% confidence interval (CI) 1.8-7.6)).
  • The increased risk of early death in patients with LMCA stenosis was neutralised in males during 1985-1994 and in females during 1995-1999.
  • Five-year mortality, exclusive of early deaths, during 1970-1984 was higher in patients with LMCA stenosis (12.8%) than in those without (8.4%) (relative risk 1.7 (95% CI 1.1-2.5)).
  • An increased risk of late mortality in patients with LMCA stenosis was neutralised in males during 1985-1994 and in females during 1995-1999.
  • CONCLUSIONS: During 1970-1999 there was a decrease of early and five-year mortality in patients with LMCA stenosis after CABG despite increase of patient age and risk factors.
  • There were gender differences so that the risk of death in patients with compared with in those without LMCA stenosis was neutralised in males during 1985-1994 and in females during 1994-1999.
  • [MeSH-major] Coronary Artery Bypass. Coronary Stenosis / mortality. Coronary Stenosis / surgery

  • MedlinePlus Health Information. consumer health - Coronary Artery Bypass Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16829104.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


95. Rostoff P, Wnuk M, Piwowarska W: [Clinical significance of exercise-induced ST-segment elevation in lead aVR and V1 in patients with chronic stable angina pectoris and strongly positive exercise test results]. Pol Arch Med Wewn; 2005 Dec;114(6):1180-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical significance of exercise-induced ST-segment elevation in lead aVR and V1 in patients with chronic stable angina pectoris and strongly positive exercise test results].
  • Clinical significance of exercise-induced ST-segment changes in lead aVR and V1 during strongly positive electrocardiographic exercise test (EET) in patients with chronic stable angina pectoris remains unclear.
  • The aim of the study was to assess the value of lead aVR and V1 on the exercise electrocardiogram for the detection of left main coronary artery stenosis (LMCAS) and its equivalent (LMCASE) in patients with chronic stable angina pectoris and the strongly positive EET result.
  • In patients with isolated exercise-induced ST elevation in lead aVR, the prevalence of LMCAS was five times more frequent than in patients without lead aVR ST elevation (25.8% vs 4.8% p<0.05).
  • There were no differences in the prevalence of LMCASE and multi-vessel coronary disease in the studied groups.
  • In patients with LMCAS significant ST elevation in lead aVR during strongly positive EET were observed (0.25 +/- 0,4 mm vs 1.43 +/- 0.6 mm p = 0.003), whereas there were no significant exercise-induced electrocardiographic changes in lead V1 (0.61 +/- 0.6 mm vs 0.77 +/- 0.6 mm p = 0.08).
  • Sensitivity of isolated exercise-induced ST elevation in lead aVR in detection of LMCAS was 85.0%, specificity - 50.0%, positive predictive value - 25.8%, negative predictive value - 94.2%, and total accuracy - 55.9%.
  • Exercise-induced ST elevation in lead aVR on the strongly positive exercise ECG may detect LMCAS in patients with chronic stable angina pectoris.
  • [MeSH-major] Angina Pectoris / complications. Coronary Disease / diagnosis. Electrocardiography. Exercise Test
  • [MeSH-minor] Adult. Aged. Chronic Disease. Coronary Angiography. Coronary Vessel Anomalies / etiology. Coronary Vessel Anomalies / physiopathology. Diagnosis, Differential. Exercise. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Radionuclide Ventriculography. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Angina.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16789487.001).
  • [Journal-full-title] Polskie Archiwum Medycyny Wewnetrznej
  • [ISO-abbreviation] Pol. Arch. Med. Wewn.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
  •  go-up   go-down


96. Ionescu CN, Donohue TJ: ECG findings in acute left main coronary artery thrombosis: a case report and review of the literature. Conn Med; 2009 Jun-Jul;73(6):333-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] ECG findings in acute left main coronary artery thrombosis: a case report and review of the literature.
  • Acute coronary syndrome due to left main coronary artery (LMCA) thrombosis is a catastrophic event associated with poor prognosis and high in-hospital mortality.
  • Unfortunately, the electrocardiographic manifestations of LMCA thrombosis are nonspecific.
  • This report describes the electrocardiogram (ECG) findings in a patient with LMCA thrombosis.
  • A new right bundle branch block (RBBB) pattern, especially when associated with ST elevation in aVR and V1, should raise suspicion of this diagnosis.
  • [MeSH-major] Coronary Thrombosis / diagnosis. Electrocardiography. Myocardial Infarction / diagnosis
  • [MeSH-minor] Acute Coronary Syndrome / etiology. Acute Coronary Syndrome / therapy. Coronary Artery Bypass. Fatal Outcome. Humans. Male. Middle Aged

  • Genetic Alliance. consumer health - Thrombosis.
  • MedlinePlus Health Information. consumer health - Heart Attack.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19637662.001).
  • [ISSN] 0010-6178
  • [Journal-full-title] Connecticut medicine
  • [ISO-abbreviation] Conn Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 6
  •  go-up   go-down


97. CHANCE Study Group: [The immediate and long-term prognosis following unprotected left main coronary artery stenting in Chinese--Chinese Registry of Unprotected Left Main Coronary Artery Stenting (CHANCE Study)]. Zhonghua Xin Xue Guan Bing Za Zhi; 2005 Mar;33(3):210-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The immediate and long-term prognosis following unprotected left main coronary artery stenting in Chinese--Chinese Registry of Unprotected Left Main Coronary Artery Stenting (CHANCE Study)].
  • OBJECTIVE: To evaluate the immediate and long-term outcomes of unprotected left main coronary artery (LMCA) stenting in Chinese patients and to approach the factors affecting the outcomes.
  • From May 1997 to March 2003 all patients in 23 hospitals undergone elective unprotected LMCA stenting with bare metal stents were enrolled into the registry.
  • Isolated LMCA stenosis was in 126 cases (56.2%) and combined with multivessel disease in 98 cases (43.8%).
  • Mean left ventricular EF was 63.9% +/- 12.3%.
  • Stents were successfully implanted into LMCA in 223 cases (99.6%) and into non-LMCA in 91 cases (92.9%).
  • Death developed in 12 cases (5.4%), including cardiac death in 10 cases (4.5%) and non-cardiac death in 2 cases (0.9%), MI in 4 cases (1.8%), TLR of LMCA in 26 cases (11.7%) and accumulated MACE in 36 cases (16.1%).
  • LVEF < 40%, female and LMCA combined with multivessel disease increased mortality, combined multivessel diseases with incomplete revascularization increased MACE.
  • CONCLUSION: Stenting for selected patients with unprotected LMCA stenosis is feasible and safe.
  • Currently, unprotected LMCA stenting should be performed in patients with LVEF >or= 40% and isolated LMCA disease or LMCA combined with multivessel diseases in whom complete revascularization could be obtained or inoperable patients.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15929812.001).
  • [ISSN] 0253-3758
  • [Journal-full-title] Zhonghua xin xue guan bing za zhi
  • [ISO-abbreviation] Zhonghua Xin Xue Guan Bing Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Multicenter Study
  • [Publication-country] China
  •  go-up   go-down


98. Hu SS, Gao RL, Gao PX, Li LH, Xiong H, Xu B, Yang YJ, Yuan JQ, Zheng Z: [Efficacy of one-stop hybrid revascularization for treatment of unprotected left main coronary artery disease]. Zhonghua Xin Xue Guan Bing Za Zhi; 2010 Jan;38(1):23-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Efficacy of one-stop hybrid revascularization for treatment of unprotected left main coronary artery disease].
  • OBJECTIVE: To evaluate the efficacy of one-stop hybrid coronary revascularization [simultaneous minimally invasive direct coronary artery bypass surgery (MIDCAB) and percutaneous coronary intervention (PCI) procedures performed in an enhanced (or called "hybrid") operative unit] for the treatment of unprotected left main coronary artery (ULMCA) disease.
  • MIDCAB procedure for grafting of the left intramammary artery (LIMA) with the left anterior descending (LAD) artery was first performed via lower partial ministernotomy on the beating heart, followed by PCI on the LMCA disease and non-LAD coronary lesions.
  • LIMA grafts and stents were patent in 5 patients at 1-year follow-up.
  • CONCLUSIONS: Our initial experience demonstrates that one-stop hybrid coronary revascularization provides a reasonable, feasible and safe alternative for selected patients with LMCA diseases.
  • [MeSH-major] Coronary Artery Disease / therapy. Myocardial Revascularization / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Angioplasty, Balloon, Coronary. Coronary Artery Bypass, Off-Pump. Female. Humans. Male. Middle Aged. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Coronary Artery Disease.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20398483.001).
  • [ISSN] 0253-3758
  • [Journal-full-title] Zhonghua xin xue guan bing za zhi
  • [ISO-abbreviation] Zhonghua Xin Xue Guan Bing Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  •  go-up   go-down


99. Furuichi S, Sangiorgi GM, Palloshi A, Godino C, Airoldi F, Montorfano M, Chieffo A, Michev I, Carlino M, Colombo A: Drug-eluting stent implantation in coronary trifurcation lesions. J Invasive Cardiol; 2007 Apr;19(4):157-62
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: A total of 15 consecutive patients undergoing percutaneous coronary intervention with DES in de novo trifurcation lesions were identified.
  • Lesions were located as follows: 13 (86.7%) at the distal left main coronary artery (LMCA) comprising the left anterior descending artery (LAD), the left circumflex artery (LCX) and an intermediate branch; 1 between the LAD, diagonal, and septal branches; and 1 between the LCX, obtuse marginal and posterior lateral branches.
  • TLR occurred in 3 patients (20%) with LMCA lesions.
  • CONCLUSION: Most trifurcation lesions were found in the distal LMCA.
  • [MeSH-major] Coronary Disease / therapy. Prosthesis Implantation / methods. Stents

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Invasive Cardiol. 2007 Jun;19(6):284; author reply 284-5 [17541134.001]
  • (PMID = 17404400.001).
  • [ISSN] 1557-2501
  • [Journal-full-title] The Journal of invasive cardiology
  • [ISO-abbreviation] J Invasive Cardiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
  •  go-up   go-down


100. Lindstaedt M, Spiecker M, Perings C, Lawo T, Yazar A, Holland-Letz T, Muegge A, Bojara W, Germing A: How good are experienced interventional cardiologists at predicting the functional significance of intermediate or equivocal left main coronary artery stenoses? Int J Cardiol; 2007 Aug 21;120(2):254-61
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] How good are experienced interventional cardiologists at predicting the functional significance of intermediate or equivocal left main coronary artery stenoses?
  • In patients with intermediate left main stem lesions clinical decision making based on FFR is safe and feasible.
  • This study was performed to assess the accuracy of visual angiographic assessment of intermediate or equivocal left main coronary artery (LMCA) stenoses by experienced interventional cardiologists when taking fractional flow reserve (FFR) measurements as the gold standard.
  • METHODS: Fifty-one patients with intermediate (40-80% diameter stenosis by angiography) or equivocal LMCA disease were evaluated by FFR.
  • CONCLUSIONS: The functional significance of intermediate and equivocal LMCA stenoses should not be based solely on angiographic assessment even by experienced interventional cardiologists.
  • [MeSH-major] Blood Flow Velocity / physiology. Blood Pressure / physiology. Cardiology / standards. Clinical Competence. Coronary Stenosis / diagnosis. Coronary Vessels / physiopathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17346818.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down






Advertisement