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1. Chen KC, Chang YL, Pan CT, Lee YC: Esophageal atypical carcinoid tumor with tracheal invasion. J Thorac Cardiovasc Surg; 2007 Aug;134(2):524-5
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  • [Title] Esophageal atypical carcinoid tumor with tracheal invasion.
  • [MeSH-major] Carcinoid Tumor / pathology. Esophageal Neoplasms / pathology. Stents. Tracheal Neoplasms / pathology
  • [MeSH-minor] Administration, Oral. Aged. Combined Modality Therapy. Diagnosis, Differential. Humans. Male. Neoplasm Invasiveness. Palliative Care. Thalidomide / administration & dosage. Tomography, X-Ray Computed

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  • (PMID = 17662809.001).
  • [ISSN] 1097-685X
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 4Z8R6ORS6L / Thalidomide
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2. Arora R, Gupta R, Sharma A, Dinda AK: Primary neuroendocrine carcinoma of thymus: a rare cause of Cushing's syndrome. Indian J Pathol Microbiol; 2010 Jan-Mar;53(1):148-51
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  • In contrast, neuroendocrine tumors (carcinoid and neuroendocrine carcinoma) of thymus are extremely rare.
  • We describe three cases of rare atypical carcinoid tumor (neuroendocrine carcinoma) of the thymus.
  • Excision of tumors and histological examination of the three tumors showed a carcinoid tumor with nuclear pleomorphism, increased mitotic activity and focal necrosis.
  • The features suggested a diagnosis of atypical carcinoid tumor in all the three cases.
  • The tumor cells in Cases 1 and 2 showed focal immunohistochemical staining for ACTH.
  • Atypical carcinoid (neuroendocrine carcinoma, well-differentiated and moderately-differentiated) of the thymus is a rare thymic tumor which carries a worse prognosis compared to thymoma and requires aggressive therapy.
  • Hence, an accurate diagnosis is essential.
  • [MeSH-major] Carcinoma, Neuroendocrine / complications. Carcinoma, Neuroendocrine / diagnosis. Cushing Syndrome / etiology. Thymus Gland / pathology. Thymus Neoplasms / complications. Thymus Neoplasms / diagnosis

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  • (PMID = 20090249.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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3. Isaka T, Maruno M, Suzuki T, Sato M, Yoshimine T: Skull metastases from atypical pulmonary carcinoid tumor in a 19-year-old man. Neurol Med Chir (Tokyo); 2006 Dec;46(12):609-13
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  • [Title] Skull metastases from atypical pulmonary carcinoid tumor in a 19-year-old man.
  • A 19-year-old man presented with a rare skull metastasis from atypical pulmonary carcinoid tumor (APCT) manifesting as headache, diplopia, and cough.
  • Head magnetic resonance imaging showed a skull base tumor extending from the posterior clinoid process to the clivus, and calvarial tumors in the right temporal and occipital bones.
  • Chest and abdominal computed tomography showed a round tumor, 4 cm in diameter, in the lower lobe of the right lung and multiple small tumors in the liver.
  • Surgery for the calvarial tumor in the right temporal bone was performed on June 27, 2003.
  • The histological diagnosis was skull metastasis of neuroendocrine tumor.
  • Partial resection of the right lower lobe was performed for the lung tumor on August 22, 2003.
  • The histological diagnosis was atypical carcinoid tumor.
  • We must consider APCT in the differential diagnosis of pulmonary tumors in adolescents, and perform follow-up observation or treatment, including surgery, if APCT is suspected.
  • [MeSH-major] Carcinoid Tumor / secondary. Lung Neoplasms / pathology. Skull Neoplasms / secondary

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  • (PMID = 17185889.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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4. Langfort R, Rudziński P, Burakowska B: [Pulmonary neuroendocrine tumors. The spectrum of histologic subtypes and current concept on diagnosis and treatment]. Pneumonol Alergol Pol; 2010;78(1):33-46
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  • [Title] [Pulmonary neuroendocrine tumors. The spectrum of histologic subtypes and current concept on diagnosis and treatment].
  • Neuroendocrine tumors of the lung represent a broad spectrum of morphologic types that share specific morphologic, immunohistochemical, ultrastructural, and molecular characteristics.
  • The classification of neuroendocrine lung tumors has changed over the last decades and currently four categories are distinguished: typical carcinoid tumor, atypical carcinoid tumor, large cell neuroendocrine carcinoma and small cell carcinoma.
  • Because of differences in clinical behavior, therapy, and prognosis, a reliable histological diagnosis, as well as clinical and pathological staging system are essential for an appropriate medical proceedings.
  • All carcinoids are malignant tumors with the potential to metastasize.
  • The majority of patients with pulmonary carcinoid have an excellent survival, even if they present with lymph node metastases.
  • Large cell neuroendocrine and small cell carcinoma progress rapidly and are generally widespread at the moment of diagnosis.
  • Increased knowledge about pulmonary neuroendocrine tumors biology and the genetic characteristics, imply that carcinoid tumors appear to have a different etiology and pathogenesis than large cell neuroendocrine and small cell carcinoma.
  • In practice, it could be easiest to conceptualize this group of pulmonary tumors as a spectrum of malignancy ranging from the low grade typical carcinoid to the highly malignant large cell neuroendocrine and small cell carcinoma.
  • Typical carcinoid tumors associated with a fairly benign behavior should be classified as low-grade neuroendocrine tumor/carcinoma (G1) and atypical carcinoid tumors as intermediate-grade tumor/carcinoma (G2).
  • Whereas, large cell neuroendocrine and small cell carcinoma should be grouped together under the designation of high-grade neuroendocrine tumor/carcinoma (G3).
  • [MeSH-major] Lung Neoplasms / diagnosis. Lung Neoplasms / therapy. Neuroendocrine Tumors / diagnosis. Neuroendocrine Tumors / therapy
  • [MeSH-minor] Carcinoid Tumor / diagnosis. Carcinoid Tumor / therapy. Carcinoma, Large Cell / diagnosis. Carcinoma, Large Cell / therapy. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / therapy. Humans. Lung / pathology. Lymphatic Metastasis. Neoplasm Staging. Prognosis. Survival Analysis

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  • (PMID = 20162517.001).
  • [ISSN] 0867-7077
  • [Journal-full-title] Pneumonologia i alergologia polska
  • [ISO-abbreviation] Pneumonol Alergol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 67
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5. Chang KP, Lee LY, Yeh AR, Dai TS, Hao SP: Endoscopic CO2 laser surgery for an atypical carcinoid tumor of the epiglottis masquerading as a supraglottic cyst. Head Neck; 2005 Nov;27(11):1004-7
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  • [Title] Endoscopic CO2 laser surgery for an atypical carcinoid tumor of the epiglottis masquerading as a supraglottic cyst.
  • BACKGROUND: Atypical carcinoid tumor is a neuroendocrine tumor; its occurrence in the larynx is uncommon, and clinical manifestations are rare.
  • We report an unusual case of atypical carcinoid tumor of the epiglottis mimicking a supraglottic retention cyst.
  • Her symptoms persisted, so we performed a laryngoscopic biopsy, which suggested an atypical carcinoid tumor.
  • Endoscopic CO2 laser surgery can be used to resect this uncommon tumor, with oncologically sound results and without surgical morbidity.
  • [MeSH-major] Carcinoid Tumor / surgery. Epiglottis / surgery. Laryngeal Neoplasms / surgery. Laser Therapy / methods
  • [MeSH-minor] Adult. Cysts / diagnosis. Diagnosis, Differential. Female. Humans. Laryngeal Diseases / diagnosis. Treatment Outcome

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  • [Copyright] (c) 2005 Wiley Periodicals, Inc.
  • (PMID = 16114009.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Ferlito A, Silver CE, Bradford CR, Rinaldo A: Neuroendocrine neoplasms of the larynx: an overview. Head Neck; 2009 Dec;31(12):1634-46
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  • In the past, there has been considerable confusion about the nature and classification of these neoplasms, but the current consensus is that there are 4 different types of laryngeal neuroendocrine tumors composed of paraganglioma, typical carcinoid, atypical carcinoid tumor, and small cell neuroendocrine carcinoma.
  • Diagnosis is based primarily on light microscopy and confirmed by immunohistochemistry and electron microscopy.
  • Precise diagnosis is essential because the natural history, treatment, and prognosis vary widely for the different neoplastic categories.
  • Atypical carcinoid tumors are more common and more aggressive.
  • Small cell neuroendocrine carcinomas are highly aggressive and should be considered disseminated at initial diagnosis.
  • It is difficult to determine the valid survival statistics for typical carcinoids because of their rarity and confusion in the literature with their atypical counterparts.
  • Atypical carcinoid tumors have a 5-year survival rate of approximately 50%, which decreases with time.
  • [MeSH-minor] Carcinoid Tumor / mortality. Carcinoid Tumor / pathology. Carcinoid Tumor / therapy. Carcinoma, Small Cell / mortality. Carcinoma, Small Cell / pathology. Carcinoma, Small Cell / therapy. Chemotherapy, Adjuvant. Combined Modality Therapy. Female. Humans. Laryngectomy / methods. Male. Neck Dissection / methods. Neoplasm Staging. Paraganglioma / mortality. Paraganglioma / pathology. Paraganglioma / therapy. Prognosis. Radiotherapy, Adjuvant. Risk Assessment. Survival Analysis

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  • (PMID = 19536850.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 89
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7. Kiratli H, Yilmaz PT, Yildiz ZI: Metastatic atypical carcinoid tumor of the inferior rectus muscle. Ophthal Plast Reconstr Surg; 2008 Nov-Dec;24(6):482-4
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  • [Title] Metastatic atypical carcinoid tumor of the inferior rectus muscle.
  • A 74-year-old man who had been treated for pulmonary atypical carcinoid tumor 3 years earlier developed diplopia.
  • Incisional biopsy of the affected muscle revealed metastatic atypical carcinoid tumor infiltration that immunostained positively for epithelial membrane antigen, synaptophysin, and chromogranin.
  • Systemic chemotherapy consisting of cisplatin and etoposide was prescribed to address the orbital tumor and a contemporaneously discovered hepatic locus.
  • Although metastatic bronchogenic carcinoid tumor in the orbit, and in the inferior rectus muscle in particular, is highly unusual, this condition must be considered in the differential diagnosis of an isolated extraocular muscle enlargement in a patient with a history of systemic carcinoid tumor.
  • [MeSH-major] Carcinoid Tumor / secondary. Eye Neoplasms / secondary. Lung Neoplasms / pathology. Muscle Neoplasms / secondary. Oculomotor Muscles
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male

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  • (PMID = 19033849.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Gustafsson BI, Kidd M, Chan A, Malfertheiner MV, Modlin IM: Bronchopulmonary neuroendocrine tumors. Cancer; 2008 Jul 1;113(1):5-21
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  • Although they share structural, morphological, immunohistochemical, and ultrastructural features, they are separated into 4 subgroups: typical carcinoid tumor (TC), atypical carcinoid tumor (AC), large-cell neuroendocrine carcinoma (LCNEC), and small-cell lung carcinoma (SCLC), which exhibit considerably different biological characteristics.
  • Less than 5% of BP-NETs exhibit hormonally related symptoms such as carcinoid syndrome, Cushing, acromegaly, and SIADH.
  • The slow-growing TC exhibit a fairly good prognosis ( approximately 88%, 5-year survival), whereas AC demonstrate a 5-year survival of approximately 50%, and the highly malignant LCNEC and SCLC5-year survival of 15% to 57% and <5%, respectively.
  • [MeSH-minor] Bronchial Neoplasms / diagnosis. Bronchial Neoplasms / genetics. Bronchial Neoplasms / pathology. Bronchial Neoplasms / therapy. Carcinoid Tumor / diagnosis. Carcinoid Tumor / genetics. Carcinoid Tumor / pathology. Carcinoid Tumor / therapy. Carcinoma, Large Cell / diagnosis. Carcinoma, Large Cell / genetics. Carcinoma, Large Cell / pathology. Carcinoma, Large Cell / therapy. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / genetics. Carcinoma, Small Cell / pathology. Carcinoma, Small Cell / therapy. Humans. Models, Biological. Neoplasm Metastasis. Prognosis

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  • [Copyright] (Copyright) 2008 American Cancer Society.
  • (PMID = 18473355.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 134
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9. Jonnakuty CG, Mezitis SG: Pulmonary atypical carcinoid tumor with metastatic involvement of the pituitary gland causing functional hypopituitarism. Endocr Pract; 2007 May-Jun;13(3):291-5
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  • [Title] Pulmonary atypical carcinoid tumor with metastatic involvement of the pituitary gland causing functional hypopituitarism.
  • OBJECTIVE: To report a unique case of a peripherally located pulmonary atypical carcinoid tumor with metastatic involvement of the pituitary, manifesting with evidence of functional hypopituitarism and compressive symptoms of dysarthria, bitemporal loss of vision, and ataxia.
  • METHODS: We present a case report, including detailed laboratory, radiologic, and pathologic findings in a 50-year-old woman with a peripherally located pulmonary atypical carcinoid tumor and a lesion metastatic to the pituitary gland.
  • RESULTS: A 50-year-old woman with a medical history of metastatic pulmonary atypical carcinoid tumor presented with symptoms of bitemporal hemianopia, ataxia, and dysarthria.
  • Findings on pathology examination were consistent with a lesion metastatic from the primary pulmonary atypical carcinoid tumor.
  • CONCLUSION: This case of metastatic involvement of the pituitary gland from a peripherally located pulmonary atypical carcinoid tumor manifesting with evidence of functional hypopituitarism is highly uncommon.
  • Therefore, heightened awareness of the possibility of a pituitary lesion metastatic from a pulmonary atypical carcinoid tumor is important.
  • [MeSH-major] Carcinoid Tumor / complications. Hypopituitarism / etiology. Lung Neoplasms / complications. Pituitary Neoplasms / complications

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  • (PMID = 17599862.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Olgac G, Peirovi F, Yilmaz A, Kutlu CA: Giant carcinoid tumor mimicking pulmonary sequestration. Ann Thorac Surg; 2007 Oct;84(4):1375-6
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  • [Title] Giant carcinoid tumor mimicking pulmonary sequestration.
  • Then a right lower lobectomy was undertaken through a hemi-clamshell incision, and histopathology revealed an atypical carcinoid tumor.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Bronchopulmonary Sequestration / diagnosis. Carcinoid Tumor / diagnosis
  • [MeSH-minor] Adult. Biopsy, Needle. Bronchoscopy / methods. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Pneumonectomy / methods. Reoperation. Risk Assessment. Severity of Illness Index. Treatment Outcome

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  • (PMID = 17889003.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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11. Gomard-Mennesson E, Sève P, De La Roche E, Collardeau-Frachon S, Lombard-Bohas C, Broussolle C: [Thymic carcinoid tumor revealed by a Cushing's syndrome: usefulness of positron emission tomography]. Rev Med Interne; 2008 Sep;29(9):751-3
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  • [Title] [Thymic carcinoid tumor revealed by a Cushing's syndrome: usefulness of positron emission tomography].
  • Ectopic adrenocorticotropic (ACTH) syndrome is a rare condition, generally due to lung or carcinoid tumors.
  • A thymic tumor was suspected and the patient had a thymectomy that revealed an atypical carcinoid tumor with pleural carcinosis.


12. Cevizci R, Karakullukçu B, van den Brekel MW, Balm AJ: Laser excision of a typical carcinoid tumor of the larynx: a case report. Kulak Burun Bogaz Ihtis Derg; 2010 Nov-Dec;20(6):305-8
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  • [Title] Laser excision of a typical carcinoid tumor of the larynx: a case report.
  • Among these, typical carcinoid tumors are the least common type.
  • Prognosis of typical carcinoid tumor is better than atypical carcinoid tumor and small cell carcinoma of the larynx.
  • Fiberoptic examination of the larynx revealed a mass located on the right aryepiglottic fold and biopsy revealed the tumor as a typical carcinoid tumor.
  • We describe CO2 laser excision of a typical carcinoid tumor of the larynx in this case report.
  • [MeSH-major] Carcinoid Tumor / surgery. Laryngeal Neoplasms / surgery. Laser Therapy / methods

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  • (PMID = 20961285.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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13. Blochin E, Stein JA, Wang NS: Atypical carcinoid metastasis to the skin. Am J Dermatopathol; 2010 Oct;32(7):735-9
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  • [Title] Atypical carcinoid metastasis to the skin.
  • Carcinoid tumors are derived from neuroendocrine cells, and are most frequently found in the gastrointestinal tract and bronchopulmonary system.
  • Cutaneous involvement of carcinoid tumors is relatively rare, with isolated case reports in the literature.
  • We detail a patient with stage IV pulmonary atypical carcinoid tumor with skin metastasis.
  • On biopsy, the tumor cells had cytologic features of a carcinoid tumor, but were arranged as infiltrating cords, small aggregates and single units, rather than the organoid or trabecular pattern seen in the primary tumor.
  • Further, along with neuroendocrine markers, the tumor cells had the staining pattern of cytokeratin 7+/cytokeratin 20-/thyroid transcription factor-1+, supporting a carcinoid tumor of lung origin.
  • Thus, this case of skin metastasis from an atypical pulmonary carcinoid tumor illustrates a unique clinical and histologic presentation.
  • [MeSH-major] Carcinoid Tumor / secondary. Lung Neoplasms / pathology. Skin Neoplasms / secondary

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  • (PMID = 20595888.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Stathopoulos GP, Papadopoulos G, Koutantos J: Long-term survival of patients with carcinoid tumor and liver metastases. J BUON; 2009 Oct-Dec;14(4):609-11
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  • [Title] Long-term survival of patients with carcinoid tumor and liver metastases.
  • PURPOSE: To determine long-term survival and long-term stable disease in patients with atypical carcinoid tumor with liver metastases.
  • METHODS: From 1993 till 2008, the records of 56 patients with atypical carcinoid were reviewed.
  • All patients had carcinoid tumors confirmed histologically.
  • [MeSH-major] Carcinoid Tumor / mortality. Liver Neoplasms / mortality. Neoplasms / mortality

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  • (PMID = 20148450.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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15. Mahomed F: Neuroendocrine cells and associated malignancies of the oral mucosa: a review. J Oral Pathol Med; 2010 Feb;39(2):121-7
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  • Primary malignant oral tumors that show a neuroendocrine phenotype display histomorphologic heterogeneity thereby giving rise to a spectrum of lesions in this rare category of oral malignancy.
  • The former is further subdivided into the Merkel cell type or the pulmonary type while the latter includes atypical carcinoid tumor and large cell NEC.
  • It remains to be determined whether histologic categorization of the remaining tumor subtypes is predictive of patient survival in oral neuroendocrine tumors.

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  • (PMID = 20002872.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 53
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16. Radfar L, Fatahzadeh M: Neuroendocrine carcinoma of the oral cavity: a case report and review of the literature. Gen Dent; 2008 Nov-Dec;56(7):714-8

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  • Based on their biological characteristics, NE carcinomas are classified into three subtypes: well-differentiated NE carcinoma (typical carcinoid tumor), moderately differentiated NE carcinoma (atypical carcinoid tumor), and poorly differentiated carcinoma (small cell carcinoma).

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  • (PMID = 19014033.001).
  • [ISSN] 0363-6771
  • [Journal-full-title] General dentistry
  • [ISO-abbreviation] Gen Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 42
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17. Peng WX, Sano T, Oyama T, Kawashima O, Nakajima T: Large cell neuroendocrine carcinoma of the lung: a comparison with large cell carcinoma with neuroendocrine morphology and small cell carcinoma. Lung Cancer; 2005 Feb;47(2):225-33
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  • Large cell neuroendocrine carcinoma (LCNEC) of the lung is a malignant neuroendocrine tumor clinicopathologically similar to and falling in-between atypical carcinoid tumor and small cell lung carcinoma (SCLC).
  • The diagnosis of LCNEC is based mainly on a characteristic neuroendocrine morphology and biological neuroendocrine differentiation.

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  • (PMID = 15639721.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm; 0 / Retinoblastoma Protein; 68238-35-7 / Keratins
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18. Wang KL, Yang YC, Wang TY, Chen JR, Chen TC, Chen HS, Su TH, Wang KG: Neuroendocrine carcinoma of the uterine cervix: A clinicopathologic retrospective study of 31 cases with prognostic implications. J Chemother; 2006 Apr;18(2):209-16
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

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  • There are two cases of atypical carcinoid tumor (ACT), four cases of large-cell neuroendocrine carcinoma (LCNEC), and 25 cases of small-cell neuroendocrine carcinoma (SCNEC).
  • Overall survival did not differ significantly in relation to surgery, tumor histology, age, FIGO stages, chemotherapeutic regimens or lymph node involvement.
  • Effective treatments of neuroendocrine cervical tumor still remain inconclusive.
  • [MeSH-minor] Adult. Carcinoid Tumor / pathology. Carcinoid Tumor / virology. Carcinoma, Large Cell / pathology. Carcinoma, Large Cell / virology. Carcinoma, Small Cell / pathology. Carcinoma, Small Cell / virology. Cervix Uteri / pathology. Cervix Uteri / virology. DNA Probes, HPV. Female. Human papillomavirus 16 / genetics. Human papillomavirus 16 / metabolism. Human papillomavirus 18 / genetics. Human papillomavirus 18 / metabolism. Humans. Middle Aged. Papillomaviridae / isolation & purification. Papillomavirus Infections / complications. Prognosis. Retrospective Studies. Survival Rate

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  • (PMID = 16736891.001).
  • [ISSN] 1120-009X
  • [Journal-full-title] Journal of chemotherapy (Florence, Italy)
  • [ISO-abbreviation] J Chemother
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / DNA Probes, HPV
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19. Bode-Lesniewska B, Hodler J, von Hochstetter A, Guillou L, Exner U, Caduff R: Late solitary bone metastasis of a primary pulmonary synovial sarcoma with SYT-SSX1 translocation type: case report with a long follow-up. Virchows Arch; 2005 Mar;446(3):310-5
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

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  • We describe a 73-year-old female patient who presented with a solitary malignant bone tumor 8 years after the resection of a lung neoplasm.
  • The bone tumor was classified as an osteosarcoma and the lung tumor as an atypical carcinoid tumor at their first respective diagnostic work-ups.
  • Reevaluation of the tumor samples at the time of the local recurrence of the bone tumor 6 years following the initial symptoms of the bone tumor lead to the reclassification of both specimens as synovial sarcomas.
  • [MeSH-minor] Aged. Diagnosis, Differential. Diagnostic Errors. Female. Humans. Immunohistochemistry. Oncogene Proteins, Fusion. Osteosarcoma / pathology. Reverse Transcriptase Polymerase Chain Reaction. Time Factors. Translocation, Genetic

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  • [Cites] Mod Pathol. 2002 Jun;15(6):589-92 [12065770.001]
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  • (PMID = 15668803.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Oncogene Proteins, Fusion; 0 / SYT-SSX fusion protein
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20. Stoll LM, Johnson MW, Burroughs F, Li QK: Cytologic diagnosis and differential diagnosis of lung carcinoid tumors a retrospective study of 63 Cases with histologic correlation. Cancer Cytopathol; 2010 Dec 25;118(6):457-67
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytologic diagnosis and differential diagnosis of lung carcinoid tumors a retrospective study of 63 Cases with histologic correlation.
  • BACKGROUND: Neuroendocrine (NE) neoplasms of the lung are a spectrum of tumors including typicalcarcinoid (TC), atypical carcinoid tumor (ACT), small cell lung carcinoma (SCLC), and large cell NEcarcinoma (LCNEC).
  • CONCLUSIONS: The significant morphologic factors for distinguishing low-grade TC from ACT, SCLC, or carcinoma remain the critical evaluation of nuclear features, chromatin patterns, and assessment of nucleoli.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy, Fine-Needle. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / pathology. Child. Diagnosis, Differential. Diagnostic Errors. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 21243734.001).
  • [ISSN] 1934-662X
  • [Journal-full-title] Cancer cytopathology
  • [ISO-abbreviation] Cancer Cytopathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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21. Spaggiari L, D' Aiuto M, Veronesi G, Pelosi G, de Pas T, Catalano G, de Braud F: Extended pneumonectomy with partial resection of the left atrium, without cardiopulmonary bypass, for lung cancer. Ann Thorac Surg; 2005 Jan;79(1):234-40
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  • The were 10 squamous cell carcinomas (60%), 2 adenocarcinomas, 1 adenosquamous carcinoma, 1 mucoepidermoid carcinoma, and 1 atypical carcinoid tumor.

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  • (PMID = 15620949.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 11
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22. Shimakage M, Kodama K, Kawahara K, Kim CJ, Ikeda Y, Yutsudo M, Inoue H: Downregulation of drs tumor suppressor gene in highly malignant human pulmonary neuroendocrine tumors. Oncol Rep; 2009 Jun;21(6):1367-72
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Downregulation of drs tumor suppressor gene in highly malignant human pulmonary neuroendocrine tumors.
  • Neuroendocrine tumors in the lung fall into four categories: typical carcinoid tumor (TC), atypical carcinoid tumor (AC), large-cell neuroendocrine carcinoma (LCNEC) and small-cell lung carcinoma (SCLC), in ascending order of malignancy.
  • Furthermore, drs knockout mice showed a tumor-prone phenotype, indicating that drs acts as a tumor suppressor gene in malignant tumor formation.
  • Our results indicate that the downregulation of drs is correlated with the development of SCLC, a highly malignant pulmonary neuroendocrine tumor.
  • [MeSH-major] Gene Expression Regulation, Neoplastic. Genes, Tumor Suppressor. Lung Neoplasms / genetics. Membrane Proteins / genetics. Neuroendocrine Tumors / genetics
  • [MeSH-minor] Adult. Aged. Blotting, Southern. Carcinoid Tumor / genetics. Carcinoma, Large Cell / genetics. Carcinoma, Neuroendocrine / genetics. Cell Line, Tumor. Down-Regulation. Female. Humans. In Situ Hybridization. Male. Middle Aged. Neoplasm Staging. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Small Cell Lung Carcinoma / genetics

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  • (PMID = 19424611.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Membrane Proteins; 0 / RNA, Messenger; 0 / SRPX protein, human
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23. Wang WP, Guo C, Berney DM, Ulbright TM, Hansel DE, Shen R, Ali T, Epstein JI: Primary carcinoid tumors of the testis: a clinicopathologic study of 29 cases. Am J Surg Pathol; 2010 Apr;34(4):519-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary carcinoid tumors of the testis: a clinicopathologic study of 29 cases.
  • Testicular carcinoid tumors are rare with only limited studies.
  • We identified 29 primary testicular carcinoid cases from 7 academic institutions.
  • Two patients had carcinoid syndrome including diarrhea, hot flashes, and palpitations.
  • Nineteen were pure carcinoid tumors, 3 were associated with cystic teratoma, 2 with cysts lacking epithelial lining, 4 with epidermoid cyst, and 1 with dermoid cyst.
  • Mitotic figures were rare in primary carcinoid tumors with only 3 cases showing more than 2 per 10 HPF; necrosis was found in only 1 case.
  • Follow-up, available in 24 cases, ranged from 1 to 228 months (mean 52.7 mo); of the 20 patients with testicular typical carcinoid tumors found premortem, all were alive at last follow-up without recurrences or metastases.
  • Of the 4 patients with a primary atypical carcinoid tumor, 1 at the time of diagnosis had retroperitoneal and lung metastases who after chemotherapy underwent resection of the retroperitoneal tumor showing metastatic yolk sac tumor and embryonal carcinoma.
  • The other 2 patients with atypical carcinoid and follow-up had no evidence of disease at 68 and 114 months.
  • Most primary carcinoid tumors of the testis have a benign clinical course even if associated with epidermoid/dermoid cysts, or histologically mature teratoma.
  • However, lesions with the morphology of atypical carcinoid can occasionally exhibit metastatic spread.
  • [MeSH-major] Carcinoid Tumor / pathology. Testicular Neoplasms / pathology

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  • [ErratumIn] Am J Surg Pathol. 2010 Jul;34(7):1075. Ubright, Thomas M [corrected to Ulbright, Thomas M]
  • (PMID = 20351489.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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24. Simsek I, Pay S, Dinc A, Erdem H, Kurt B: Atypical carcinoid tumor of the thymus with ectopic ACTH production developed during the course of etanercept treatment--case report. Clin Rheumatol; 2007 Sep;26(9):1561-2
Hazardous Substances Data Bank. Etanercept .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical carcinoid tumor of the thymus with ectopic ACTH production developed during the course of etanercept treatment--case report.
  • Ever since the introduction of anti-tumor necrosis factor (TNF) agents, concerns have been raised regarding their potential for developing malignancy.
  • We report the development of thymic atypical carcinoid tumor 9 months after the initiation of etanercept therapy in a patient having refractory spondylarthritis.
  • [MeSH-major] Antibodies, Monoclonal / adverse effects. Carcinoid Tumor / chemically induced. Immunoglobulin G / adverse effects. Thymus Neoplasms / chemically induced. Tumor Necrosis Factor-alpha / antagonists & inhibitors
  • [MeSH-minor] Adult. Etanercept. Humans. Male. Pituitary ACTH Hypersecretion / etiology. Receptors, Tumor Necrosis Factor. Spondylarthritis / drug therapy

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  • (PMID = 17061154.001).
  • [ISSN] 0770-3198
  • [Journal-full-title] Clinical rheumatology
  • [ISO-abbreviation] Clin. Rheumatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Immunoglobulin G; 0 / Receptors, Tumor Necrosis Factor; 0 / Tumor Necrosis Factor-alpha; OP401G7OJC / Etanercept
  •  go-up   go-down


25. Kim DH, Song MH, Kim DH: Malignant carcinoid tumor of the common bile duct: report of a case. Surg Today; 2006;36(5):485-9
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant carcinoid tumor of the common bile duct: report of a case.
  • Carcinoid tumors of the extrahepatic bile duct are exceedingly rare and account for between 0.1% and 2% of all gastrointestinal carcinoid tumors, with most reported cases arising from the gallbladder.
  • We herein present what we believe is only the 47th reported case of a primary carcinoid tumor occurring in the extrahepatic bile ducts.
  • Laboratory and imaging studies gave results that were consistent with a malignant obstruction in the common bile duct.
  • The tumor had invaded the adjacent pancreatic tissues.
  • The final pathologic diagnosis was well-differentiated carcinoid tumor of a malignant nature.
  • [MeSH-major] Carcinoid Tumor / surgery. Common Bile Duct Neoplasms / surgery. Pancreaticoduodenectomy

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  • (PMID = 16633759.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 21
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26. Felekouras E, Petrou A, Bramis K, Prassas E, Papaconstantinou I, Dimitriou N, Pazaiti A, Tsigris C, Giannopoulos A: Malignant carcinoid tumor of the cystic duct: a rare cause of bile duct obstruction. Hepatobiliary Pancreat Dis Int; 2009 Dec;8(6):640-6
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant carcinoid tumor of the cystic duct: a rare cause of bile duct obstruction.
  • BACKGROUND: Carcinoid tumors of the extrahepatic biliary tree are extremely rare malignancies, accounting for 0.2%-2% of all gastrointestinal carcinoid tumors, while carcinoids of the cystic duct are an uncommon entity and an extremely unusual cause of bile duct obstruction.
  • METHODS: After an extensive literature review, we retrospectively analysed 61 cases of carcinoid tumor of the biliary tree as well as one additional case of a 60-year-old female with symptoms and laboratory/imaging examination findings compatible with those of a malignant biliary tract obstruction.
  • Compared to cholangiocarcinoma, analysis of the reviewed group indicates an increased incidence of extrahepatic carcinoid tumors in younger persons along with a slight female predominance.
  • CONCLUSIONS: Carcinoid tumors obstructing the biliary tree are extremely difficult to diagnose preoperatively, and nearly impossible to differentiate from non-neuroendocrine tumors.
  • As surgery offers the only potential cure for both biliary carcinoids and cholangiocarcinoma, we recommend aggressive surgical therapy as the treatment of choice in every case of potentially resectable biliary tumor.
  • [MeSH-major] Bile Duct Neoplasms / complications. Carcinoid Tumor / complications. Cholestasis / etiology. Cystic Duct / pathology

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  • (PMID = 20007084.001).
  • [ISSN] 1499-3872
  • [Journal-full-title] Hepatobiliary & pancreatic diseases international : HBPD INT
  • [ISO-abbreviation] HBPD INT
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 69
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27. Vigg A, Mantri S, Swarnalata G, Mulay K: Atypical carcinoid tumour. Indian J Chest Dis Allied Sci; 2005 Jul-Sep;47(3):213-5
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  • [Title] Atypical carcinoid tumour.
  • Carcinoid tumour is a rare entity accounting for less than two percent of bronchial neoplasms.
  • More offten, it presents as a central endobronchial tumour.
  • The peripheral type of carcinoid tumour is relatively rare.
  • [MeSH-major] Carcinoid Tumor / pathology. Lung Neoplasms / pathology
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Female. Humans

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  • (PMID = 16022152.001).
  • [ISSN] 0377-9343
  • [Journal-full-title] The Indian journal of chest diseases & allied sciences
  • [ISO-abbreviation] Indian J Chest Dis Allied Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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28. Stătescu G, Serban I, Dobreanu E: [Neglected peritonitis of rare origin: atypical carcinoid]. Rev Med Chir Soc Med Nat Iasi; 2006 Apr-Jun;110(2):381-3
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  • [Title] [Neglected peritonitis of rare origin: atypical carcinoid].
  • [Transliterated title] Peritonită neglijată de cauză rară: carcinoid atipic.
  • We present a clinical case of ileal carcinoid tumor manifested to a man about 53 years old, which was operated first time in emergency when right hemicolectomy was performed and after that reintervention for a small fistula.
  • In conclusion we can say that acute appendicitis with generalized peritonitis could be one of form by manifestation of this tumor:ileal carcinoid tumor.
  • [MeSH-major] Appendicitis / etiology. Carcinoid Tumor / complications. Ileal Neoplasms / complications. Peritonitis / etiology

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  • (PMID = 17802949.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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29. John BM, Song MH, Park YS, Jo YJ, Kim SH, Lee HH, Kim SK, Jung SH, Kim DH, Kim DH: [A case of carcinoid tumor of the common bile duct]. Korean J Gastroenterol; 2006 Apr;47(4):320-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of carcinoid tumor of the common bile duct].
  • Majority of malignant neoplasms arising from the extrahepatic bile duct are adenocarcinomas.
  • Carcinoid tumors at this site are extremely rare.
  • We report a 67-year-old woman with malignant carcinoid tumor of the common bile duct.
  • She underwent Whipple's operation and was diagnosed as malignant carcinoid tumor histologically and immunohistochemically.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Common Bile Duct Neoplasms / diagnosis

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  • (PMID = 16632986.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
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30. Davì MV, Bodei L, Francia G, Bartolomei M, Oliani C, Scilanga L, Reghellin D, Falconi M, Paganelli G, Lo Cascio V, Ferdeghini M: Carcinoid crisis induced by receptor radionuclide therapy with 90Y-DOTATOC in a case of liver metastases from bronchial neuroendocrine tumor (atypical carcinoid). J Endocrinol Invest; 2006 Jun;29(6):563-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoid crisis induced by receptor radionuclide therapy with 90Y-DOTATOC in a case of liver metastases from bronchial neuroendocrine tumor (atypical carcinoid).
  • It is well known that some procedures performed in diagnostic and therapeutic management of endocrine tumors, such as agobiopsy and hepatic chemoembolization, can be associated with the occurrence of symptoms related to the release of vasoactive amines and/or hormonal peptides from tumor cell lysis.
  • This is the first report of a severe carcinoid crisis developed after receptor radionuclide therapy with 90Y-DOTATOC administered in a patient affected by liver metastases from bronchial neuroendocrine tumor (atypical carcinoid).
  • [MeSH-major] Bronchial Neoplasms / pathology. Liver Neoplasms / secondary. Malignant Carcinoid Syndrome / chemically induced. Octreotide / analogs & derivatives
  • [MeSH-minor] Aged. Bone Neoplasms / secondary. Carcinoid Tumor / drug therapy. Carcinoid Tumor / radiotherapy. Humans. Male. Yttrium Radioisotopes / adverse effects

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  • (PMID = 16840837.001).
  • [ISSN] 0391-4097
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / 90Y-octreotide, DOTA-Tyr(3)-; 0 / Yttrium Radioisotopes; RWM8CCW8GP / Octreotide
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31. Strehl MA, Scheich M, Ott I, Müller-Hermelink HK, Hagen R, Völker HU: [Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?]. Laryngorhinootologie; 2009 Mar;88(3):186-90
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?].
  • [Transliterated title] Mittelohradenom/Mittelohrkarzinoid--ein unproblematischer Tumor?
  • OBJECTIVES: Adenomas/carcinoid tumors of the middle ear are very rare tumors of young to middle aged patients.
  • The terms adenoma and carcinoid tumor of the middle ear can be used as synonyms, with the WHO favouring the term middle ear adenoma (MEA).
  • METHODS AND PATIENTS: This study describes the clinical course and the diagnostic challenges in four cases of this rare tumor entity.
  • In two cases a tumor recurrence was documented with one case recurring six times.
  • The histological differential diagnosis can also be problematic; in one case with a highly atypical morphology it was impossible to arrive at a definite diagnosis during the analysis of a frozen section.
  • The presented cases in this study and the analysis of previously published cases shows that the typical progression described by the current WHO-classification with unproblematic surgical management of the tumor and an uncomplicated further clinical course does not always correspond to reality.
  • [MeSH-major] Adenoma / diagnosis. Carcinoid Tumor / diagnosis. Ear Neoplasms / diagnosis. Ear, Middle
  • [MeSH-minor] Adult. Cholesteatoma, Middle Ear / diagnosis. Cholesteatoma, Middle Ear / pathology. Cholesteatoma, Middle Ear / surgery. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local / surgery. Otoscopy. Reoperation. Tomography, X-Ray Computed

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  • (PMID = 19065497.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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32. Pein MK, Holzhausen H, Kösling S, Bartel-Friedrich S, Knipping S: [Atypical carcinoid of the larynx. Case report and review of literature]. HNO; 2010 Aug;58(8):812-7
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  • [Title] [Atypical carcinoid of the larynx. Case report and review of literature].
  • To date, no diagnosis or treatment guidelines have been established for this entity.
  • Initial laryngoscopy showed a tumour at the laryngeal epiglottic surface.
  • Staging demonstrated an atypical carcinoid tumour with local lymph-node metastasis.
  • CONCLUSION: In atypical carcinoid tumours total resection as well as bilateral neck dissection should be performed, even in cN0 cases.
  • [MeSH-major] Carcinoid Tumor / surgery. Laryngeal Neoplasms / surgery

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  • (PMID = 20480128.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Germany
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33. Ulusan S, Kizilkilic O, Yildirim T, Tercan F, Bolat F, Yildirim S: Primary hepatic carcinoid tumor: dynamic CT findings. Abdom Imaging; 2005 May-Jun;30(3):281-5
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  • [Title] Primary hepatic carcinoid tumor: dynamic CT findings.
  • Most carcinoid tumors involve the gastrointestinal tract or respiratory system.
  • Primary hepatic carcinoid tumor is a rare entity.
  • She was diagnosed with primary hepatic carcinoid tumor based on radiologic and laboratory findings, namely a mass in the fifth segment of the liver and markedly elevated levels of 5-hydroxyindole acetic acid in the urine.
  • Histologic and immunohistochemical findings of the resected liver segment showed a malignant carcinoid tumor of the liver.
  • [MeSH-major] Carcinoid Tumor / radiography. Liver Neoplasms / radiography. Tomography, X-Ray Computed

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  • (PMID = 15785908.001).
  • [ISSN] 0942-8925
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Zinnamosca L, Petramala L, Cotesta D, Marinelli C, Sciomer S, Cavallaro G, Ciardi A, Massa R, De Toma G, Filetti S, Letizia C: Primary aldosteronism due to adrenocortical adenoma with concurrent ileum carcinoid tumor: case report. Endocrine; 2010 Dec;38(3):313-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary aldosteronism due to adrenocortical adenoma with concurrent ileum carcinoid tumor: case report.
  • Primary aldosteronism (PA) with synchronous carcinoid syndrome is extremely rare occurrence.
  • In this article, we describe a case of PA due to adrenocortical adenoma ("aldosteronoma") and concurrent malignant carcinoid tumor of ileum.
  • [MeSH-major] Adrenal Cortex Neoplasms / complications. Adrenocortical Adenoma / complications. Carcinoid Tumor / complications. Hyperaldosteronism / complications. Hyperaldosteronism / etiology. Ileal Neoplasms / complications

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  • (PMID = 20972725.001).
  • [ISSN] 1559-0100
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Sánchez Lihón J: [Carcinoid tumors of the rectum: clinical - pathological correlation]. Rev Gastroenterol Peru; 2009 Apr-Jun;29(2):140-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Carcinoid tumors of the rectum: clinical - pathological correlation].
  • [Transliterated title] Tumor carcinoide del recto: correlacion clinico-patologica.
  • OBJECTIVE: The purpose of this study was to determine the clinico-pathologic correlation of carcinoid tumors of the rectum.
  • MATERIALS AND METHODS: We reviewed the medical records and pathology of 20 patients with carcinoid tumors of the rectum seen at the Instituto de Enfermedades Neoplásicas (INEN), between 1980 and 2006 RESULTS: There was no difference between sex.
  • 7 cases hat atypical histopathologic from them 2 patients dead, all had metastasis and tumor sizes were 3 to 6 cm.
  • CONCLUSIONS: The tumor size, the atypical histopathologic features, the infiltration of the wall and metastasis are associated with aggressive behavior and bad prognosis.
  • [MeSH-major] Carcinoid Tumor / epidemiology. Rectal Neoplasms / epidemiology

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  • (PMID = 19609329.001).
  • [ISSN] 1022-5129
  • [Journal-full-title] Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
  • [ISO-abbreviation] Rev Gastroenterol Peru
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Peru
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36. Sato H, Kajiya H, Kanai G, Hirukawa T, Tanaka H, Kakuta T, Inomoto C, Osamura RY: Atypical thymic carcinoid associated with Cushing's syndrome. Tokai J Exp Clin Med; 2010 Jul;35(2):78-84
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

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  • [Title] Atypical thymic carcinoid associated with Cushing's syndrome.
  • A 56-year-old Japanese woman with adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome (CS) was admitted to hospital, where she was diagnosed as having a mediastinal tumor with ectopic ACTH production.
  • The tumor and associated lymph node metastases were resected endoscopically, and the pathological diagnosis was atypical thymic carcinoid.
  • Immunostaining for ACTH, chromogranin A, synaptophysin, and neuron-specific enolase was positive in the carcinoid cells.
  • Since somatostatin (SS) and SS analogues inhibit the growth of carcinoid via the SS receptor (SSTR) 2, we evaluated the expression of SSTR2 in the carcinoid cells using reverse transcription-polymerase chain reaction, and this confirmed the expression of SSTR2 in the carcinoid cells.
  • Our experience of this patient with CS due to an ectopic ACTH-producing atypical thymic carcinoid suggests that SS analogues may be useful for treatment of carcinoid showing expression of SSTR2.
  • [MeSH-major] Carcinoid Tumor. Cushing Syndrome / etiology. Mediastinal Neoplasms. Thymus Neoplasms


37. Van Brandt V, Heyman S, Van Marck E, Hendriks J, Van Schil P: Atypical presentation of an atypical carcinoid. Ann Thorac Surg; 2009 Dec;88(6):2004-6
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  • [Title] Atypical presentation of an atypical carcinoid.
  • Carcinoids are malignant neuroendocrine tumors consisting of a spectrum of neoplasms from low-grade typical carcinoid to high-grade small cell carcinoma.
  • Therefore, presently no uniform criteria are available for diagnosis, staging, risk assessment, and treatment.
  • Generally, carcinoid tumors are indolent.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Thymus Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Humans. Male. Thymectomy / methods. Tomography, X-Ray Computed

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  • (PMID = 19932277.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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38. Eloy-Garcia Carrasco C, Benguigui Benadiva J, Martinez Garcia S, Sanz Trelles A, Palacios S: Atypical primary carcinoid tumour of the skin. J Cutan Pathol; 2006 Sep;33 Suppl 2:32-4
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  • [Title] Atypical primary carcinoid tumour of the skin.
  • We present a new case of a primary carcinoid tumour of the skin.
  • The mitotic index (4/10 HPF) warrants classification of this case as atypical.
  • Literature review showed this to be only the seventh case of primary carcinoid tumour of the skin.
  • Although the number of cases is too small to draw definitive conclusions, information to date suggests that this type of tumour can be expected to have a benign behaviour, despite the presence in some cases of criteria suggestive of uncertainty, such as the presence of mitosis.
  • [MeSH-major] Carcinoid Tumor / pathology. Head and Neck Neoplasms / pathology. Skin Neoplasms / pathology

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  • (PMID = 16972951.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 7
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39. Nannini N, Bertolini F, Cavazza A, Casali C, Mengoli MC, Rossi G: Atypical carcinoid with prominent mucinous stroma: a hitherto unreported variant of pulmonary neuroendocrine tumor. Endocr Pathol; 2010 Jun;21(2):120-4
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  • [Title] Atypical carcinoid with prominent mucinous stroma: a hitherto unreported variant of pulmonary neuroendocrine tumor.
  • Carcinoid tumors of the lung may show several growth patterns and cell types.
  • We report here a previously undescribed case of primary pulmonary atypical carcinoid with prominent mucinous stroma, an exceedingly rare variant of carcinoid tumor so far reported only in the thymus.
  • The tumor was discovered in a 50-year-old, non-smoker woman, and pursued an aggressive behavior.
  • The lack of TTF-1 expression and the positive staining with hormonal receptors made the diagnosis very challenging.
  • Differential diagnosis with other primary and metastatic mucin-rich tumors is also discussed.
  • [MeSH-major] Carcinoid Tumor / pathology. Carcinoma, Neuroendocrine / pathology. Lung Neoplasms / pathology. Mucus / metabolism
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / analysis. Combined Modality Therapy. Fatal Outcome. Female. Humans. Immunohistochemistry. Middle Aged. Neoplasm Staging. Pneumonectomy

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  • (PMID = 20195926.001).
  • [ISSN] 1559-0097
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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40. Salamone L, McCarthy S, Salem RR: Atypical cystic carcinoid tumors of the liver. J Clin Gastroenterol; 2010 Nov-Dec;44(10):e256-9
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  • [Title] Atypical cystic carcinoid tumors of the liver.
  • Carcinoid metastases in the liver are typically solid, hypervascular lesions.
  • We report 3 cases of cystic carcinoid tumors in the liver with radiographic findings.
  • Two were metastatic from primary carcinoid tumors of the small intestine and one was not associated with any extra hepatic lesion at presentation or during 5 years of subsequent follow-up.
  • [MeSH-major] Carcinoid Tumor / pathology. Intestinal Neoplasms / pathology. Liver Neoplasms / pathology. Neoplasms, Cystic, Mucinous, and Serous / pathology

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  • (PMID = 20463590.001).
  • [ISSN] 1539-2031
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. McIntire M, Shah ND, Kim AW, Gattuso P, Liptay MJ: Cytologic imprints of giant atypical bronchopulmonary carcinoid tumor of the lung with extensive oncocytic component. Diagn Cytopathol; 2008 Dec;36(12):887-90
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  • [Title] Cytologic imprints of giant atypical bronchopulmonary carcinoid tumor of the lung with extensive oncocytic component.
  • Bronchopulmonary carcinoid tumors are found in less than 2 of 100,000 people yearly and comprise approximately 1-2% of all lung neoplasms.
  • Diagnosis is usually made by bronchoscopy with bronchial brushings or biopsy.
  • We present the cytologic imprint findings of a case of a 66-year-old man with an atypical giant bronchopulmonary carcinoid with extensive oncocytic component, who underwent a total right pneumonectomy.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Carcinoma, Neuroendocrine / pathology. Lung Neoplasms / diagnosis

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18855906.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Hubalewska-Dydejczyk A, Fröss-Baron K, Gołkowski F, Sowa-Staszczak A, Mikołajczak R, Huszno B: 99mTc-EDDA/HYNIC-octreotate in detection of atypical bronchial carcinoid. Exp Clin Endocrinol Diabetes; 2007 Jan;115(1):47-9
Hazardous Substances Data Bank. DISODIUM CALCIUM EDTA .

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  • [Title] 99mTc-EDDA/HYNIC-octreotate in detection of atypical bronchial carcinoid.
  • We present a case of a 40-year-old women operated on because of lung carcinoid tumour in 2002.
  • Owing to severe bone pains and carcinoid symptoms the patient was referred for the 90Y-DOTA-octreotate treatment.
  • CONCLUSIONS: SRS with a new 99mTc marked somatostatin analogue - octreotate allows for a more sensitive detection of metastatic leasions in carcinoid tumours.
  • The usefulness of 18F-FDG PET, widely used as a powerful imaging technique in clinical oncology, is limited in detection of carcinoid tumours due to the low proliferative activity.
  • [MeSH-major] Carcinoid Tumor / radiography. Lung Neoplasms / radiography. Mediastinal Neoplasms / radiography. Radiopharmaceuticals / administration & dosage

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  • (PMID = 17286235.001).
  • [ISSN] 0947-7349
  • [Journal-full-title] Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
  • [ISO-abbreviation] Exp. Clin. Endocrinol. Diabetes
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / 6-hydrazinopyridine-3-carboxylic acid; 0 / Hydrazines; 0 / Nicotinic Acids; 0 / Organotechnetium Compounds; 0 / Radiopharmaceuticals; 51110-01-1 / Somatostatin; 5657-17-0 / EDDA; 9G34HU7RV0 / Edetic Acid; G083B71P98 / pentetreotide
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43. Okano Y, Inayama M, Hatakeyama N, Hino H, Iwahara Y, Motoki T, Naruse K, Yokota Y, Ogushi F: Autopsy case of rapid progressive atypical carcinoid of the lung discovered with multiple nodular shadows. J Med Invest; 2008 Feb;55(1-2):142-6
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  • [Title] Autopsy case of rapid progressive atypical carcinoid of the lung discovered with multiple nodular shadows.
  • We report an autopsy case of rapid progressive atypical carcinoid of the lung discovered as multiple nodular shadows.
  • Samples from the wall-side pleural lesion were obtained by video-assisted thoracoscopic surgery under local anesthesia, and histological examination led to a diagnosis of atypical carcinoid.
  • We believe that early detection is crucial in the treatment of atypical carcinoid due to poor prognosis.
  • [MeSH-major] Carcinoid Tumor / pathology. Carcinoid Tumor / radiography. Lung / radiography. Lung Neoplasms / pathology. Lung Neoplasms / radiography

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  • (PMID = 18319557.001).
  • [ISSN] 1343-1420
  • [Journal-full-title] The journal of medical investigation : JMI
  • [ISO-abbreviation] J. Med. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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44. Detterbeck FC: Management of carcinoid tumors. Ann Thorac Surg; 2010 Mar;89(3):998-1005
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  • [Title] Management of carcinoid tumors.
  • Primary bronchopulmonary carcinoids comprise a significant proportion of carcinoid tumors.
  • The clinical presentation allows prediction of the diagnosis and cell type and directs evaluation and treatment.
  • Young age, central tumor, and no nodal enlargement are highly suggestive of typical carcinoid.
  • All bronchopulmonary carcinoids are malignant (though indolent), and surgical intervention is the mainstay of treatment.
  • Mediastinoscopy is suggested when there is moderate suspicion of atypical carcinoid (central cN1 or peripheral cN0), with lobectomy and lymphadenectomy if the mediastinal nodes are benign.
  • For a high suspicion of atypical carcinoid (central cN2, peripheral cN1, 2), imaging for distant metastases and mediastinoscopy is suggested, with multimodality treatment for an atypical carcinoid with N2 involvement.
  • [MeSH-major] Bronchial Neoplasms. Carcinoid Tumor. Lung Neoplasms

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  • [Copyright] 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20172187.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 67
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45. Meinardi JR, van den Berg G, Wolffenbuttel BH, Kema IP, Dullaart RP: Cyclical Cushing's syndrome due to an atypical thymic carcinoid. Neth J Med; 2006 Jan;64(1):23-7
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  • [Title] Cyclical Cushing's syndrome due to an atypical thymic carcinoid.
  • A tumour in the right anterior mediastinum was revealed on octreotide receptor scintigraphy, which had initially been overlooked on computed tomography (CT) scanning.
  • A thymic carcinoid tumour was suspected, which was supported by increased levels of urinary serotonin, while platelet serotonin and urinary 5-hydroxyindoleacetic acid levels were normal.
  • The tumour was removed surgically and histological examination revealed an atypical thymic carcinoid tumour.
  • Repeated measurement of urinary cortisol excretion is then required to establish or rule out the diagnosis.
  • [MeSH-major] ACTH Syndrome, Ectopic / complications. Carcinoid Tumor / complications. Cushing Syndrome / etiology. Thymus Neoplasms / complications


46. García-Yuste M, Matilla JM, Cueto A, Paniagua JM, Ramos G, Cañizares MA, Muguruza I, Spanish Multi-centric Study of Neuroendocrine Tumours of the Lung for the Spanish Society of Pneumonology and Thoracic Surgery (EMETNE-SEPAR): Typical and atypical carcinoid tumours: analysis of the experience of the Spanish Multi-centric Study of Neuroendocrine Tumours of the Lung. Eur J Cardiothorac Surg; 2007 Feb;31(2):192-7
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  • [Title] Typical and atypical carcinoid tumours: analysis of the experience of the Spanish Multi-centric Study of Neuroendocrine Tumours of the Lung.
  • BACKGROUND: This study examines the experience of the Spanish Multi-centric Study of Neuroendocrine Tumours of the Lung with patients treated surgically for typical and atypical carcinoid tumours.
  • METHODS: From 1980 to 2002, 661 patients were treated surgically for 569 typical carcinoid tumours and 92 atypical carcinoid tumours.
  • Three hundred and four cases were studied retrospectively from 1980 to 1997 (261 typical carcinoid and 43 atypical carcinoid tumours); the other 357 new cases (308 typical carcinoid and 49 atypical carcinoid tumours) were collected prospectively from 1998 to 2002.
  • RESULTS: In the total of the patients, 5-year survival for different tumours was as follows: typical carcinoid: overall survival 97%; with nodal involvement 100%; atypical carcinoid: overall 78%; with nodal involvement 60%.
  • A significant difference in survival was found between patients in the retrospective and prospective groups with atypical carcinoid and nodal involvement.
  • The comparative analysis of several factors in typical and atypical carcinoid tumours showed a significant difference for mean age, tumour size, nodal involvement and distant metastases.
  • Sleeve resection could be performed in central typical and atypical carcinoid tumours, avoiding pneumonectomy.
  • [MeSH-major] Carcinoid Tumor / surgery. Lung Neoplasms / surgery

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  • (PMID = 17196822.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Germany
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47. Davini F, Gonfiotti A, Comin C, Caldarella A, Mannini F, Janni A: Typical and atypical carcinoid tumours: 20-year experience with 89 patients. J Cardiovasc Surg (Torino); 2009 Dec;50(6):807-11
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  • [Title] Typical and atypical carcinoid tumours: 20-year experience with 89 patients.
  • AIM: The aim of this study was to conduct a retrospective clinical and pathological analysis of the authors' 20-year experience on treatment of typical and atypical carcinoid tumours.
  • METHODS: A retrospective clinical and pathological analysis was conducted on 89 patients treated for bronchial carcinoid neoplasms at the Division of Thoracic Surgery, Hospital of Florence (Italy) between January 1986 and January 2006.
  • Diagnosis was made with radiological methods such as plain chest roentgenography, computed tomography (CT), and bronchoscopy.
  • In 38 cases of central lesion the diagnosis was obtained by endobronchial biopsy.
  • A correct pathological diagnosis was obtained before surgery in 58 patients; in the others resected cases the correct diagnosis was determined by intraoperative histology during surgery.
  • RESULTS: There were 63 (70.8%) typical carcinoid (TC) and 26 (29,2%) atypical carcinoid (AC).
  • On the basis of the hystopatological documentation of all patients operated before 1999 (60 patients) the authors observed that in 4 cases (6.6%) the diagnosis has changed from AC to TC while only 1 case (1.6%) of AC was classified as TC with new criterias.
  • CONCLUSIONS: Anatomical resection, including formal lobectomy (or pneumonectomy when indicated) and radical mediastinal lymphadenectomy, should be performed in carcinoid tumours.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Lung Neoplasms / diagnosis. Pneumonectomy / methods
  • [MeSH-minor] Adult. Aged. Biopsy. Bronchoscopy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Lymph Node Excision / methods. Male. Mediastinum. Middle Aged. Retrospective Studies. Time Factors. Tomography, X-Ray Computed. Treatment Outcome. Young Adult

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  • (PMID = 19935614.001).
  • [ISSN] 0021-9509
  • [Journal-full-title] The Journal of cardiovascular surgery
  • [ISO-abbreviation] J Cardiovasc Surg (Torino)
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
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48. Wurtz A, Benhamed L, Conti M, Bouchindhomme B, Porte H: Results of systematic nodal dissection in typical and atypical carcinoid tumors of the lung. J Thorac Oncol; 2009 Mar;4(3):388-94
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  • [Title] Results of systematic nodal dissection in typical and atypical carcinoid tumors of the lung.
  • BACKGROUND: To determine the lymphatic spread frequency and location in patients, who underwent lung resection for carcinoid tumors, associated with systematic nodal dissection.
  • METHODS: From January 1998 to June 2007, 54 patients underwent anatomic lung resection associated with systematic nodal dissection for tumors classified as typical (TC) or atypical carcinoid according to 1999 World Health Organization criteria.
  • In the atypical group (n = 12) 2 patients were classified N1 (16.6%) and 2 N2 (16.6%).Five of the 6 N2 patients showed a single skip metastasis not discovered by preoperative evaluation (83.3%).The lymphatic spread was correlated with age < or = 35 years (p = 0.01) and a tumor size > or = 3 cm (p = 0.002).Median follow-up was 57 months.
  • [MeSH-major] Carcinoid Tumor / secondary. Lung Neoplasms / pathology. Lymph Node Excision / methods. Lymph Nodes / surgery

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  • [ErratumIn] J Thorac Oncol. 2009 May;4(5):670
  • (PMID = 19247085.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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49. Oukabli M, Blechet C, Harket A, Gaillard F, Garand G, Fetissof F: [Atypical carcinoid of the arytenoid: report of six cases]. Ann Pathol; 2008 Feb;28(1):2-8
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  • [Title] [Atypical carcinoid of the arytenoid: report of six cases].
  • In order to illustrate the clinical and histological presentations of laryngeal atypical carcinoids and their potential course, we report six cases.
  • For each case, we noted the mitotic index, the quality of the resection, the limits of the tumor and the presence of necrosis.
  • The tumor is more aggressive when the mitotic index is high and an unfavorable course is observed when there are lymphatic emboli or when the Ki67 index is higher than 5%.
  • [MeSH-major] Arytenoid Cartilage / pathology. Carcinoid Tumor / surgery. Laryngeal Neoplasms / surgery

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  • (PMID = 18538708.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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50. Tewari M, Kumar V, Mishra RR, Shukla HS: Gallbladder carcinoid masquerading as gallbladder carcinoma. Hepatobiliary Pancreat Dis Int; 2009 Jun;8(3):326-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gallbladder carcinoid masquerading as gallbladder carcinoma.
  • BACKGROUND: Carcinoid of the gallbladder is rare.
  • A provisional diagnosis of gallbladder carcinoma was made.
  • RESULT: Histopathological examination revealed it was a neuroendocrine carcinoma, atypical carcinoid of the gallbladder.
  • CONCLUSION: Gallbladder carcinoid has a poor outcome, requires aggressive treatment, and should be considered as one of the rare but possible gallbladder lesions.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Carcinoma / diagnosis. Gallbladder Neoplasms / diagnosis
  • [MeSH-minor] Adult. Cholecystectomy. Diagnosis, Differential. Female. Humans. Laparotomy

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  • (PMID = 19502178.001).
  • [ISSN] 1499-3872
  • [Journal-full-title] Hepatobiliary & pancreatic diseases international : HBPD INT
  • [ISO-abbreviation] HBPD INT
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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51. Endo T, Hasegawa T, Tezuka Y, Kanai Y, Otani S, Yamamoto S, Tetsuka K, Sato Y, Endo S, Sohara Y: [Atypical pulmonary carcinoid tumor with abnormal elevation of serum gastrin-releasing peptide precursor: report of a case]. Kyobu Geka; 2008 Oct;61(11):993-5
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  • [Title] [Atypical pulmonary carcinoid tumor with abnormal elevation of serum gastrin-releasing peptide precursor: report of a case].
  • We report a rare case of atypical pulmonary carcinoid tumor accompanied by elevation of serum gastrin-releasing peptide precursor (ProGRP).
  • Chest computed tomography (CT) revealed a solitary pulmonary tumor in the left lower lobe with sub-carinal lymph node enlargement.
  • Transbronchial lung biopsy showed a pulmonary carcinoid, therefore left lower lobectomy with mediastinal lymph node dissection was performed.
  • Histopathological diagnosis showed an atypical pulmonary carcinoid tumor.
  • [MeSH-major] Biomarkers, Tumor / blood. Carcinoid Tumor / diagnosis. Lung Neoplasms / diagnosis. Peptide Fragments / blood

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  • (PMID = 18939440.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Peptide Fragments; 0 / Recombinant Proteins; 0 / pro-gastrin-releasing peptide (31-98)
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52. Pelosi G, Rodriguez J, Viale G, Rosai J: Typical and atypical pulmonary carcinoid tumor overdiagnosed as small-cell carcinoma on biopsy specimens: a major pitfall in the management of lung cancer patients. Am J Surg Pathol; 2005 Feb;29(2):179-87
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  • [Title] Typical and atypical pulmonary carcinoid tumor overdiagnosed as small-cell carcinoma on biopsy specimens: a major pitfall in the management of lung cancer patients.
  • Seven patients with typical or atypical pulmonary carcinoid tumors overdiagnosed as small-cell carcinoma on bronchoscopic biopsies are described.
  • The carcinoid tumors presented as either central or peripheral lesions composed of tumor cells with granular, sometimes coarse chromatin pattern, high levels of chromogranin A/synaptophysin immunoreactivity, and low (<20%) Ki-67 (MIB-1) labeling index.
  • The tumor stroma contained thin-walled blood vessels.
  • Small-cell carcinomas always showed central tumor location, finely dispersed nuclear chromatin, lower levels of chromogranin A/synaptophysin, and high (>50%) Ki-67 (MIB-1) labeling index.
  • Judging from this study, overdiagnosis of carcinoid tumor as small-cell carcinoma in small crushed bronchial biopsies remains a significant potential problem in a worldwide sample of hospital settings.
  • Careful evaluation of hematoxylin and eosin sections remains the most important tool for the differential diagnosis, with evaluation of tumor cell proliferation by Ki-67 (MIB-1) labeling index emerging from our review as the most useful ancillary technique for the distinction.
  • [MeSH-major] Carcinoid Tumor / pathology. Carcinoma, Small Cell / pathology. Lung Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Ki-67 Antigen / metabolism. Male. Middle Aged


53. Stević R, Jovanović D, Masulović D, Pesut D, Vasić N, Stojić J: [Clinico-radiological characteristics of bronchial carcinoid]. Acta Chir Iugosl; 2009;56(4):51-5
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  • [Title] [Clinico-radiological characteristics of bronchial carcinoid].
  • OBJECTIVES: To review clinical and radiological characteristics of a patients with bronchial carcinoid.
  • METHODS: In this retrospective study, we reviewed the clinical, pathological and imaging findings in 42 patients diagnosed with bronchial carcinoid during the seven years period.
  • Thirty patients had typical and 12 atypical bronchial carcinoid.
  • Tumor was localized in 28 patients in the left, and 14 in the right lung.
  • On radiographs carcinoid manifested as tumor shadow in 40.5%, nodule and atelectasis in 21.4% cases each respectively, pleural effusion and pneumonia in 7.1% each respectively and hyperinflation in 2.4% of the cases.
  • Computerized tomography revealed endoluminal tumor in 30.9% patients.
  • CONCLUSION: Major imaging findings are central, tumor mass or nodule and obstruction signs like atelectasis.
  • Diagnosis is confirmed by pathological examination of samples taken by bronchoscopy or surgery.
  • [MeSH-major] Bronchial Neoplasms / radiography. Carcinoid Tumor / radiography

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  • (PMID = 20419997.001).
  • [ISSN] 0354-950X
  • [Journal-full-title] Acta chirurgica Iugoslavica
  • [ISO-abbreviation] Acta Chir Iugosl
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia
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54. Vidal A, Lorenzo MJ, Isidro ML, Cordido F: Atypical thymic carcinoid in multiple endocrine neoplasia type 1 syndrome. J Endocrinol Invest; 2007 Jul-Aug;30(7):601-2
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  • [Title] Atypical thymic carcinoid in multiple endocrine neoplasia type 1 syndrome.
  • An asymptomatic, non-smoker patient carrier of a multiple endocrine neoplasia syndrome type 1 (MEN1) mutation was diagnosed with invasive atypical thymic carcinoid tumor.
  • After surgical treatment the tumor reappeared albeit without metastasis.
  • Thymic carcinoid is a well-known cause of mortality in MEN1, and usually metastatic disease is present at diagnosis.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Multiple Endocrine Neoplasia Type 1 / complications. Thymus Neoplasms / diagnosis


55. Lee DH, Cho HH, Cho YB: Typical carcinoid tumor of the nasal cavity. Auris Nasus Larynx; 2007 Dec;34(4):537-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Typical carcinoid tumor of the nasal cavity.
  • They can be classified typical carcinoid, atypical carcinoid and small cell carcinoma, neuroendocrine type.
  • The tumor histology and prognosis correlate closely.
  • The typical carcinoid tumors are well differentiated with benign course.
  • The treatment of the typical carcinoid is a conservative surgery and the prognosis is good.
  • But, typical carcinoid tumor of the nasal cavity was extremely rare, so the treatment has not been established.
  • We report a case of typical carcinoid tumor of the nasal cavity in a 76-year-old man who treated by conservative surgery using sinus endoscopy.
  • To the best of our knowledge this is the first report on an typical carcinoid in the nasal cavity.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Nasal Cavity. Nose Neoplasms / diagnosis

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  • (PMID = 17481837.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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56. Ito T, Kim K, Taira M, Kinoshita M, Ikeda N: [Atypical carcinoid of the lung with abnormal elevation of serum ProGRP level; report of a case]. Kyobu Geka; 2010 Jun;63(6):505-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Atypical carcinoid of the lung with abnormal elevation of serum ProGRP level; report of a case].
  • We report a rare case of an atypical carcinoid of the lung with the elevation of serum ProGRP.
  • Pulmonary carcinoid was pathologically suggested by a transbronchial lung biopsy.
  • Pathological diagnosis was atypical carcinoid.
  • [MeSH-major] Biomarkers, Tumor / blood. Carcinoid Tumor / diagnosis. Lung Neoplasms / diagnosis. Peptide Fragments / blood

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  • (PMID = 20533746.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Peptide Fragments; 0 / Recombinant Proteins; 0 / pro-gastrin-releasing peptide (31-98)
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57. Seshamani M, Einhorn E, Mirza N: Atypical carcinoid of the larynx and potential complications of the carcinoid syndrome: a case report. Ear Nose Throat J; 2009 Jan;88(1):E1
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  • [Title] Atypical carcinoid of the larynx and potential complications of the carcinoid syndrome: a case report.
  • In addition to conducting a metastatic workup, we determined that it was necessary to evaluate the functional status of the tumor prior to excision because the SSRI could precipitate a carcinoid syndrome.
  • We discuss the characteristics and management of different neuroendocrine carcinomas of the larynx, and we review the potential complications of the carcinoid syndrome.
  • [MeSH-major] Carcinoid Tumor / pathology. Laryngeal Neoplasms / pathology. Laryngoscopy / methods. Malignant Carcinoid Syndrome / etiology

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  • (PMID = 19172557.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Ampollini L, Carbognani P, Rusca M, Bobbio A: Resection of giant typical carcinoid tumor with cardiopulmonary bypass support. Thorac Cardiovasc Surg; 2010 Dec;58(8):500-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Resection of giant typical carcinoid tumor with cardiopulmonary bypass support.
  • Carcinoids, defined as well-differentiated neuroendocrine tumors, are classified as typical or atypical based on their microscopic pathological features.
  • We present the surgical strategy used to achieve a left pneumonectomy and the indications for cardiopulmonary bypass (CPB) support in a patient with a huge typical carcinoid tumor.
  • [MeSH-major] Carcinoid Tumor / surgery. Cardiopulmonary Bypass. Lung Neoplasms / surgery. Pneumonectomy

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  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 21110279.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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59. Jain D, Sharma MC, Singh K, Gupta NP: Primary carcinoid tumor of the kidney: case report and brief review of literature. Indian J Pathol Microbiol; 2010 Oct-Dec;53(4):772-4
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  • [Title] Primary carcinoid tumor of the kidney: case report and brief review of literature.
  • Primary carcinoid tumor of the kidney is an extremely uncommon tumor.
  • We herein describe a case of renal carcinoid with atypical features.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Carcinoid Tumor / pathology. Kidney / pathology. Kidney Neoplasms / diagnosis. Kidney Neoplasms / pathology

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  • (PMID = 21045413.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
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60. Uchino K, Okada M, Sakamoto T, Yuki T, Mimura T, Tsubota N: Bronchoplasty for bronchial carcinoid tumor without removing lung parenchyma. Jpn J Thorac Cardiovasc Surg; 2006 Aug;54(8):345-7
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  • [Title] Bronchoplasty for bronchial carcinoid tumor without removing lung parenchyma.
  • Computed tomographic scans demonstrated a tumor 20 mm in diameter situated on the left main to upper lobar bronchus that eventually was proved to be a typical carcinoid tumor by transbronchial biopsy.
  • We performed bronchial resection with atypical bronchoplasty, which preserves lung parenchyma in cases of s-T1N0M0 disease.
  • [MeSH-major] Bronchi / surgery. Bronchial Neoplasms / surgery. Carcinoid Tumor / surgery. Pulmonary Surgical Procedures / methods

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  • (PMID = 16972641.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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61. Kurabayashi T, Minamikawa T, Nishijima S, Tsuneki I, Tamura M, Yanase T, Hashidate H, Shibuya H, Motoyama T: Primary strumal carcinoid tumor of the ovary with multiple bone and breast metastases. J Obstet Gynaecol Res; 2010 Jun;36(3):567-71
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  • [Title] Primary strumal carcinoid tumor of the ovary with multiple bone and breast metastases.
  • Although primary carcinoid tumor of the ovary is an extremely rare neoplasm, survival is excellent if the disease is confined to one ovary.
  • Herein, we present a case of primary strumal carcinoid tumor of the ovary, stage IA, borderline malignancy, in a 34-year-old woman.
  • Histological findings of the right ovary indicated higher atypical nuclei, higher mitotic rate and focal necrosis of tumorous cells in some areas, findings that are compatible with atypical carcinoid of the lung.
  • The results in the present case indicate that an ovarian carcinoid tumor found to be 'atypical carcinoid' according to pulmonary carcinoid criteria or immunohistochemical staining (i.e. highly positive for topoisomerase IIalpha and Ki-67) may have a poor prognosis.
  • [MeSH-major] Bone Neoplasms / secondary. Breast Neoplasms / secondary. Carcinoid Tumor / secondary. Ovarian Neoplasms / pathology. Struma Ovarii / secondary


62. Ciment A, Gil J, Teirstein A: Late recurrent pulmonary typical carcinoid tumor: case report and review of the literature. Mt Sinai J Med; 2006 Oct;73(6):884-6
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  • [Title] Late recurrent pulmonary typical carcinoid tumor: case report and review of the literature.
  • Carcinoid tumors are uncommon pulmonary neoplasms.
  • They are classified histologically as either atypical or typical.
  • Atypical carcinoids are aggressive malignancies that require radical surgical resection and have a guarded prognosis with a propensity to metastasize and recur.
  • Recurrence of a typical pulmonary carcinoid tumor more than a decade after initial resection is very rare.
  • A patient with recurrence of a typical carcinoid tumor 11 years after resection of the primary lesion with one involved lymph node is reported here.
  • Late recurrences are rare in both atypical and typical varieties, but are much more common in atypical carcinoids.
  • The patient reported here represents the fifth case of recurrence of a typical carcinoid tumor more than ten years after resection.
  • This suggests that, after resection of a typical carcinoid neoplasm, patients should be monitored carefully, especially if lymph node metastases are present at the time of surgery.
  • [MeSH-major] Carcinoid Tumor / physiopathology. Lung Neoplasms / physiopathology. Neoplasm Recurrence, Local

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  • (PMID = 17117316.001).
  • [ISSN] 0027-2507
  • [Journal-full-title] The Mount Sinai journal of medicine, New York
  • [ISO-abbreviation] Mt. Sinai J. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
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63. Naccini B, Fitting JW, Letovanec I: [Current approach to bronchial carcinoid tumors]. Rev Med Suisse; 2007 Nov 21;3(134):2655-6, 2658-60, 2662
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  • [Title] [Current approach to bronchial carcinoid tumors].
  • Neuroendocrine tumors of the lung comprise typical and atypical carcinoids, as well as large cell neuroendocrine carcinomas and small cell carcinomas.
  • However carcinoid tumours differ from the latter two by their clinical presentation, radiographic, histological appearances, and treatment modalities as well as prognosis.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Carcinoid Tumor / therapy. Lung Neoplasms / diagnosis. Lung Neoplasms / therapy

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  • (PMID = 18159699.001).
  • [ISSN] 1660-9379
  • [Journal-full-title] Revue médicale suisse
  • [ISO-abbreviation] Rev Med Suisse
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 31
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64. Otake Y, Aoki M, Nakanishi T, Hashimoto K: Atypical carcinoid of thymus associated with multiple endocrine neoplasia syndrome type 1. Gen Thorac Cardiovasc Surg; 2010 Oct;58(10):534-7
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  • [Title] Atypical carcinoid of thymus associated with multiple endocrine neoplasia syndrome type 1.
  • Thymic carcinoid associated with multiple endocrine neoplasia syndrome type 1 (MEN-1) is a rare tumor.
  • We report a case of MEN-1-related thymic carcinoid.
  • Histological examination revealed atypical carcinoid with infiltration.
  • MEN-1-related thymic carcinoid is often insidious with a poor prognosis.
  • We suggest chest computed tomography scan or magnetic resonance imaging for MEN-1 patients and serological or genetic screening for patients with thymic carcinoid to screen for MEN-1.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Multiple Endocrine Neoplasia Type 1 / diagnosis. Thymus Neoplasms / diagnosis


65. de Matos LL, Trufelli DC, das Neves-Pereira JC, Danel C, Riquet M: Cushing's syndrome secondary to bronchopulmonary carcinoid tumor: report of two cases and literature review. Lung Cancer; 2006 Sep;53(3):381-6
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  • [Title] Cushing's syndrome secondary to bronchopulmonary carcinoid tumor: report of two cases and literature review.
  • Bronchopulmonary carcinoid tumors have been associated with a variety of endocrine disorders including Cushing's syndrome (CS), which is caused by ectopic adrenocorticotrophic hormone (ACTH) secretion.
  • We report two cases of CS secondary to bronchopulmonary carcinoid tumors.
  • After lobectomy, a typical bronchopulmonary carcinoid was diagnosed.
  • After lobectomy, an atypical bronchopulmonary carcinoid was diagnosed.
  • Neither of these patients had hypophysary microadenomas, adrenal adenomas or recurrence of CS after surgical treatment, demonstrating that CS was caused solely by the presence of the bronchopulmonary carcinoid tumors.
  • [MeSH-major] Bronchial Neoplasms / complications. Bronchial Neoplasms / diagnosis. Carcinoid Tumor / complications. Carcinoid Tumor / diagnosis. Cushing Syndrome / complications. Cushing Syndrome / diagnosis. Lung Neoplasms / complications. Lung Neoplasms / diagnosis


66. Rickman OB, Vohra PK, Sanyal B, Vrana JA, Aubry MC, Wigle DA, Thomas CF Jr: Analysis of ErbB receptors in pulmonary carcinoid tumors. Clin Cancer Res; 2009 May 15;15(10):3315-24
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  • [Title] Analysis of ErbB receptors in pulmonary carcinoid tumors.
  • PURPOSE: This study aimed to investigate the expression of the ErbB family of receptor tyrosine kinases in pulmonary typical carcinoid and atypical carcinoid tumors and to understand the role of epidermal growth factor receptor (EGFR) signaling in pulmonary carcinoid tumor proliferation.
  • EXPERIMENTAL DESIGN: Surgically resected typical carcinoid (n = 24) and atypical carcinoid (n = 7) tumor tissues were analyzed by immunohistochemical staining for EGFR, ErbB2, ErbB3, and ErbB4.
  • Sequencing of tumor DNA of exons 18 to 21 of the EGFR gene and the KRAS gene was carried out.
  • Biochemical analysis of lung carcinoid cell lines was used to investigate EGFR signal transduction and response to erlotinib inhibition.
  • RESULTS: The analysis showed that 45.8% of typical carcinoid and 28.6% of atypical carcinoid tumors express EGFR, 100% of the tumors lack expression of ErbB2, and 100% have moderate to intense staining for ErbB3 and ErbB4.
  • Sequencing of tumor DNA of exons 18 to 21 of the EGFR gene revealed the absence of tyrosine kinase domain mutations in these tumors.
  • Because EGFR and KRAS mutations tend not to be present at the same time, we sequenced the KRAS gene from pulmonary carcinoid tumor DNA and found that 100% were wild-type.
  • Using a lung carcinoid cell line that expresses EGFR, we found that erlotinib reduced proliferation by inhibiting EGFR signal transduction.
  • CONCLUSIONS: Our findings suggest clinical potential for the use of EGFR inhibitors in the treatment of patients with pulmonary carcinoid tumors, particularly for patients with EGFR-positive pulmonary carcinoid tumors not amenable to surgical resection.
  • [MeSH-major] Carcinoid Tumor / pathology. Lung Neoplasms / pathology. Receptor, Epidermal Growth Factor / analysis. Receptor, ErbB-2 / analysis. Receptor, ErbB-3 / analysis

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  • (PMID = 19447869.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Quinazolines; DA87705X9K / Erlotinib Hydrochloride; EC 2.7.10.1 / ERBB2 protein, human; EC 2.7.10.1 / ERBB4 protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-2; EC 2.7.10.1 / Receptor, ErbB-3; EC 2.7.10.1 / Receptor, ErbB-4; EC 3.6.5.2 / ras Proteins
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67. Mendes S, Gallego J, Caldeira J, Palhano M, Cruz J, Cravino J: [Pulmonary carcinoid tumors--ten years experience]. Rev Port Cir Cardiotorac Vasc; 2005 Jan-Mar;12(1):21-4
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  • [Title] [Pulmonary carcinoid tumors--ten years experience].
  • Pulmonary carcinoid tumors are rare, accounting for as many as 2% of all pulmonary neoplasms and for 10% of carcinoid tumors overall.
  • They have a subclassification into typical classed as low-grade malignant neoplasm and atypical more aggressive, with more potential to cause local invasion.
  • In this paper, the authors report a retrospective study of 25 patients, who had the diagnosis of pulmonary carcinoid tumors and had been operated between January of 1994 and August of 2004.
  • We conclude that this tumors must be considered malignant in the surgical approach.
  • [MeSH-major] Carcinoid Tumor / surgery. Lung Neoplasms / surgery

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  • (PMID = 15895123.001).
  • [ISSN] 0873-7215
  • [Journal-full-title] Revista portuguesa de cirurgia cardio-torácica e vascular : órgão oficial da Sociedade Portuguesa de Cirurgia Cardio-Torácica e Vascular
  • [ISO-abbreviation] Rev Port Cir Cardiotorac Vasc
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Portugal
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68. Davies-Husband CR, Montgomery P, Premachandra D, Hellquist H: Primary, combined, atypical carcinoid and squamous cell carcinoma of the larynx: a new variety of composite tumour. J Laryngol Otol; 2010 Feb;124(2):226-9
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  • [Title] Primary, combined, atypical carcinoid and squamous cell carcinoma of the larynx: a new variety of composite tumour.
  • OBJECTIVE: We report the first case of a laryngeal composite tumour consisting of a squamous cell carcinoma combined with an atypical carcinoid.
  • Primary neuroendocrine neoplasms represent a rare, heterogeneous subset of laryngeal malignancies, comprising typical carcinoid, atypical carcinoid, small cell carcinoma and paraganglioma.
  • Primary combined neuroendocrine and squamous cell carcinoma of the larynx is even more rarely encountered, with only 14 publications of this so-called composite tumour to date.
  • CONCLUSION: The treatment of primary neoplasms comprising more than one histological type is tailored to the most biologically aggressive tumour.
  • Accurate diagnosis of the histological nature of laryngeal composite tumours is imperative to ensure optimal therapy.
  • [MeSH-major] Carcinoid Tumor / pathology. Carcinoma, Squamous Cell / pathology. Laryngeal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 19930775.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 20
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69. Kim BN, Sohn DK, Hong CW, Han KS, Chang HJ, Jung KH, Lim SB, Choi HS, Jeong SY, Park JG: Atypical endoscopic features can be associated with metastasis in rectal carcinoid tumors. Surg Endosc; 2008 Sep;22(9):1992-6
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  • [Title] Atypical endoscopic features can be associated with metastasis in rectal carcinoid tumors.
  • Tumor size was associated with metastasis (p < 0.001).
  • Endoscopic features associated with metastasis were tumor shape, surface change, and color (p < 0.001).
  • Atypical endoscopic features occurred more frequently as the size of the tumor increased (p < 0.001).
  • For tumors 10-19 mm in diameter, atypical surface change was associated with metastasis (p = 0.007).
  • In particular, atypical surface change may be useful in determining treatment plans for tumors 10-19 mm in diameter.
  • [MeSH-major] Carcinoid Tumor / secondary. Colonoscopy. Rectal Neoplasms / pathology. Sigmoidoscopy
  • [MeSH-minor] Adult. Aged. Bone Neoplasms / secondary. Color. Female. Humans. Hyperemia / etiology. Intestinal Mucosa / pathology. Liver Neoplasms / secondary. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Retrospective Studies. Surface Properties. Tumor Burden. Ulcer / pathology

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  • (PMID = 18568372.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Grant] United States / PHS HHS / / NCC-0710362
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
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70. Bapat U, Mackinnon NA, Spencer MG: Carcinoid tumours of the larynx. Eur Arch Otorhinolaryngol; 2005 Mar;262(3):194-7
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  • [Title] Carcinoid tumours of the larynx.
  • They can be divided into typical, atypical and small cell tumours on the basis of their histopathological differentiation.
  • The tumour histology and prognosis correlate closely.
  • The typical carcinoid tumours are well differentiated with a benign course.
  • The atypical carcinoid tumours are poorly differentiated with an aggressive course.
  • We present two cases with similar history and clinical findings-one typical and the other atypical-and discuss the relevant literature.
  • [MeSH-major] Carcinoid Tumor / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 15164214.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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71. Lingamfelter D, Hoffman L, Verma A, Depond W, Lankachandra K: Giant atypical carcinoid of the liver with vascular metastases and local sinusoidal invasion: a case report. J Med Case Rep; 2007;1:47

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant atypical carcinoid of the liver with vascular metastases and local sinusoidal invasion: a case report.
  • We present the case of a 46 year old woman with a giant, 23-centimeter, atypical carcinoid of the liver.
  • Histologically, the tumor displayed mild cytologic atypia, abundant necrosis, and intravascular metastases, the last feature of which was identified by immunohistochemical markers for chromogranin and synaptophysin.
  • Also described is the unusual sinusoidal infiltration, or "spillage," of tumor cells into the surrounding liver parenchyma, a feature that has not been described as far as we are aware but may suggest an aggressive clinical course.
  • Even though an exact definition of atypia for these lesions apparently does not exist at this point, the multiple atypical features in this case strongly suggest the diagnosis of atypical carcinoid of the liver, thus far an altogether rare and vaguely reported entity.
  • As more cases arise in the medical literature, it may be worthwhile to establish a set of guidelines to define atypical hepatic carcinoids and other gastrointestinal carcinoids, although survivorship data thus far indicates no significant difference in the prognosis between typical versus atypical variants.

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  • (PMID = 17626622.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1950516
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72. Kuczma JA, Grzywa M: [Broncho-pulmonary carcinoid with the cardiac arrhythmia manifestation]. Pol Arch Med Wewn; 2006 Oct;116(4):971-3
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  • [Title] [Broncho-pulmonary carcinoid with the cardiac arrhythmia manifestation].
  • We are presenting the case of a 60-year-old woman (OM ) with a bronchial-pulmonary carcinoid which the only, first and dominating symptom was paroxysmal atrial tachycardia, as well as ventricular group extrasystoles.
  • The patient underwent urgent surgery after an episode of massive pulmonary haemorrhage--surgery included excision of the upper lobe of the left lung containing the tumour and mediastinal lymph nodes.
  • On microscopic examination, an atypical carcinoid was diagnosed.
  • The current imaging examinations and determinations of 5-HIO uringexcretion acid do not indicate relapse of the tumour.
  • [MeSH-major] Arrhythmias, Cardiac / etiology. Bronchial Neoplasms / complications. Carcinoid Tumor / complications. Lung Neoplasms / complications

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  • (PMID = 18416299.001).
  • [Journal-full-title] Polskie Archiwum Medycyny Wewnetrznej
  • [ISO-abbreviation] Pol. Arch. Med. Wewn.
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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73. Krüger S, Buck AK, Blumstein NM, Pauls S, Schelzig H, Kropf C, Schumann C, Mottaghy FM, Hombach V, Reske SN: Use of integrated FDG PET/CT imaging in pulmonary carcinoid tumours. J Intern Med; 2006 Dec;260(6):545-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of integrated FDG PET/CT imaging in pulmonary carcinoid tumours.
  • OBJECTIVE: To evaluate the usefulness of integrated FDG PET/CT in pulmonary carcinoid tumours.
  • METHODS: We studied 13 patients (mean age +/- 1 SD, 57 +/- 11 years) with pulmonary carcinoid tumours.
  • Final histological diagnosis confirmed 12 typical and one atypical pulmonary carcinoid.
  • None of the patients had recurrent carcinoid disease or died during follow-up (864 +/- 218 days).
  • Mean standardized uptake value (SUV) of (18)F-fluorodeoxyglucose (FDG) in typical carcinoids was 3.0 +/- 1.5 (range 1.2 - 6.6); SUV in the atypical carcinoid was remarkably high with a value of 8.5.
  • FDG uptake in pulmonary carcinoid tumours is often lower than expected for malignant tumours.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Image Enhancement / methods. Lung Neoplasms / diagnosis. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 17116005.001).
  • [ISSN] 0954-6820
  • [Journal-full-title] Journal of internal medicine
  • [ISO-abbreviation] J. Intern. Med.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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74. Buonerba C, Gallo C, Di Lorenzo G, Romeo V, Marinelli A: Ten-year adjuvant treatment with somatostatin analogs in a patient with atypical carcinoid of the lung. Anticancer Drugs; 2010 Apr;21(4):465-8
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  • [Title] Ten-year adjuvant treatment with somatostatin analogs in a patient with atypical carcinoid of the lung.
  • Both typical carcinoid and atypical carcinoid (AC) of the lung are surgically curable, but AC carries a considerably worse prognosis because of a relatively high rate of recurrence.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Carcinoid Tumor / drug therapy. Lung Neoplasms / drug therapy. Somatostatin / therapeutic use

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  • (PMID = 20075713.001).
  • [ISSN] 1473-5741
  • [Journal-full-title] Anti-cancer drugs
  • [ISO-abbreviation] Anticancer Drugs
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 51110-01-1 / Somatostatin
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75. Tiktinsky E, Horne T, Agranovich S, Lantsberg S: Intramuscular metastasis of carcinoid tumor: a rare manifestation. Clin Nucl Med; 2008 Jul;33(7):484-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramuscular metastasis of carcinoid tumor: a rare manifestation.
  • A 43-year-old man presented with a 2-month history of left upper lobectomy due to an atypical lung carcinoid tumor.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Lung Neoplasms / diagnosis. Muscle Neoplasms / diagnosis. Muscle Neoplasms / radionuclide imaging. Octreotide

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  • (PMID = 18580236.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] RWM8CCW8GP / Octreotide
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76. Divisi D, Crisci R: Carcinoid tumors of the lung and multimodal therapy. Thorac Cardiovasc Surg; 2005 Jun;53(3):168-72
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  • [Title] Carcinoid tumors of the lung and multimodal therapy.
  • Diagnosis was obtained in 28 patients with fibre-optic bronchoscopy and in 14 patients with CT-guided trans-thoracic needle biopsy.
  • RESULTS: There were 26 typical and 16 atypical carcinoids.
  • The 3-year and the 5-year survival rates in the typical and atypical carcinoid groups were 100 % and 96 % vs. 81 % and 68 %, respectively (p < 0.001).
  • [MeSH-major] Carcinoid Tumor / surgery. Lung Neoplasms / surgery. Pneumonectomy

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  • (PMID = 15926097.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Chromogranin A; 0 / Chromogranins; 0 / Synaptophysin; RWM8CCW8GP / Octreotide
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77. Giordano G, Corcione L, Giordano D, D'Adda T, Gnetti L, Ferri T: Primary moderately differentiated neuroendocrine carcinoma (atypical carcinoid) of the larynx: A case report with immunohistochemical and molecular study. Auris Nasus Larynx; 2009 Apr;36(2):228-31
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  • [Title] Primary moderately differentiated neuroendocrine carcinoma (atypical carcinoid) of the larynx: A case report with immunohistochemical and molecular study.
  • In this paper, we report the case of a moderately differentiated neuroendocrine carcinoma NEC (atypical carcinoid) of the larynx in a heavy smoker 67-year-old woman, with a history of hoarseness, dysphagia and dyspnea.
  • Here, we emphasized the morphological criteria for a correct pathological diagnosis.
  • Moreover, because it has been demonstrated that many neuroendocrine neoplasms and malignant lesions of the larynx can be related to human papilloma virus (HPV), for the first time, we probed to verify if laryngeal neuroendocrine carcinoma could be due to an HPV infection by using polymerase chain reaction amplification (PCR) of tumoural DNA.
  • [MeSH-major] Carcinoid Tumor / pathology. Laryngeal Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Biopsy. DNA Mutational Analysis. DNA Probes, HPV / genetics. DNA, Neoplasm / genetics. Female. Humans. Laryngectomy. Larynx / pathology. Lymph Node Excision. Neoplasm Invasiveness. Neoplasm Staging. Polymerase Chain Reaction. Tumor Suppressor Protein p53 / genetics

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  • (PMID = 18617341.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA Probes, HPV; 0 / DNA, Neoplasm; 0 / Tumor Suppressor Protein p53
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78. Kayhan FT, Başaran EG: Typical carcinoid tumor of the larynx in a woman: a case report. J Med Case Rep; 2010;4:321

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Typical carcinoid tumor of the larynx in a woman: a case report.
  • Histopathologically, neuroendocrine tumors can be classified into four types: typical carcinoid tumors, atypical carcinoid tumors, small cell neuroendocrine tumors and paragangliomas.
  • Typical carcinoid tumor of the larynx is a particularly rare occurrence.
  • We present a case of this rare disease, and review and discuss its diagnosis and treatment.
  • Results of the histopathologic examination and immunohistochemical analysis were consistent with typical carcinoid tumor of the larynx.
  • CONCLUSION: Carcinoid tumors require an accurate diagnosis because of their varied clinical behavior and prognosis.
  • A correct pathologic diagnosis is essential, differentiating the tumors from other neuroendocrine neoplasms and medullary cancer of the thyroid gland.
  • Currently, conservative surgical resection without elective neck dissection is the recommended treatment for typical carcinoid tumor of the larynx.
  • Additional cases and case series with long-term follow-up will be useful for understanding the nature of this tumor and should clarify the prognosis.

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  • (PMID = 20939901.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2964737
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79. Liao H, Rao H, Zhang X, Lin Y, Jie M, Fu J, Long H, Rong T, Lin P: [Retrospective study of clinicopathological characteristics in bronchopulmonary carcinoid]. Zhongguo Fei Ai Za Zhi; 2010 Jun;13(6):591-7
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  • [Title] [Retrospective study of clinicopathological characteristics in bronchopulmonary carcinoid].
  • BACKGROUND AND OBJECTIVE: Bronchopulmonary carcinoid (BPC) account for less than 2% of all primary lung malignant tumors, but few related studies were reported.
  • First, the corresponding paraffin blocks reexamined, slice up and stained, multiple pathologists re-consulted, and its subsets (typical carcinoid, TC; atypical carcinoid, AC) defined.
  • [MeSH-major] Carcinoid Tumor / pathology. Lung Neoplasms / pathology

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  • (PMID = 20681445.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Ki-67 Antigen; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / TTF1 protein, human
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80. Mineo TC, Guggino G, Mineo D, Vanni G, Ambrogi V: Relevance of lymph node micrometastases in radically resected endobronchial carcinoid tumors. Ann Thorac Surg; 2005 Aug;80(2):428-32
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  • [Title] Relevance of lymph node micrometastases in radically resected endobronchial carcinoid tumors.
  • Histologic examination showed 47 (85%) typical carcinoid and 8 (14.5%) atypical.
  • Twelve patients were pN1 (8 typical, 4 atypical); after reanalysis another 8 revealed micrometastasis, 6 N1 micrometastasis (5 typical, 1 atypical), and 2 N2 micrometastasis (2 atypical), increasing subjects with nodal involvement (pN1 and N micrometastasis) from 12 (21.8%) to 20 (36.4%; p = 0.01).
  • Micrometastases were more frequent in atypical carcinoids (p = 0.002).
  • Local recurrence developed in 3 (5.4%) patients: 2 pN1 (1 typical, 1 atypical) and 1 N1-micrometastasis (1 typical).
  • Distant relapse occurred in 2 (3.6%) patients, both N2 micrometastasis (2 atypical).
  • [MeSH-major] Bronchial Neoplasms / pathology. Carcinoid Tumor / pathology

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  • [CommentIn] Ann Thorac Surg. 2005 Aug;80(2):433 [16039179.001]
  • (PMID = 16039178.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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81. Bini A, Brandolini J, Cassanelli N, Davoli F, Dolci G, Sellitri F, Stella F: Typical and atypical pulmonary carcinoids: our institutional experience. Interact Cardiovasc Thorac Surg; 2008 May;7(3):415-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Typical and atypical pulmonary carcinoids: our institutional experience.
  • Pulmonary carcinoids are rare malignant neoplasms, accounting for 2-5% of all lung tumors, with an approximate annual incidence of 2.3-2.8 cases per million of the population.
  • All the patients underwent preoperative fibrobronchoscopy: preoperative diagnosis was made in 28 patients (52%).
  • Fifty-four patients were followed with a mean time of observation of 67 months: 6 (11%) deaths occurred, at a mean period of 49 months after surgery; there were no postoperative deaths.
  • Overall, 5-year survival was 91%, 10 years 83%: 5-year survival was 91% for typical carcoinoids (TC) vs. 88% for atypical (AC), 10 years 91% for TC and 44% for AC (significant value, P=0.0487).
  • Carcinoid tumors are a distinct group of neuroendocrine tumors with a good prognosis in most cases.
  • [MeSH-major] Bronchial Neoplasms. Carcinoid Tumor

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  • (PMID = 18349148.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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82. Hamad AM, Rizzardi G, Marulli G, Rea F: Nodal recurrence of pulmonary carcinoid 30 years after primary resection. J Thorac Oncol; 2008 Jun;3(6):680-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nodal recurrence of pulmonary carcinoid 30 years after primary resection.
  • We present a case of nodal recurrence of carcinoid tumor in a 48-year-old male patient, 30 years after resection of primary tumor.
  • Octreoscan was used for diagnosis and localization of the mass.
  • Surgical resection was successful and histopathologic examination revealed lymph node infiltrated with atypical carcinoid.
  • [MeSH-major] Carcinoid Tumor / surgery. Lung Neoplasms / surgery. Neoplasm Recurrence, Local / diagnosis. Pneumonectomy / methods
  • [MeSH-minor] Adult. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Positron-Emission Tomography. Time Factors. Tomography, X-Ray Computed

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  • (PMID = 18520814.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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83. Gillenwater A, Lewin J, Roberts D, El-Naggar A: Moderately differentiated neuroendocrine carcinoma (atypical carcinoid) of the larynx: a clinically aggressive tumor. Laryngoscope; 2005 Jul;115(7):1191-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Moderately differentiated neuroendocrine carcinoma (atypical carcinoid) of the larynx: a clinically aggressive tumor.
  • METHODS: Patient, tumor, treatment, and outcome data were collected from medical records.
  • Nine patients were alive 3 years after diagnosis.
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Larynx / radiation effects. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Survival Rate

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  • (PMID = 15995505.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Krysiak R, Okopień B, Herman ZS: [Current concepts on diagnosis and treatment of carcinoid]. Przegl Lek; 2007;64(2):103-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Current concepts on diagnosis and treatment of carcinoid].
  • Carcinoid tumours are relatively rare neuroendocrine neoplasms that often present as diagnostic dilemmas due to obscure or non-specific symptomatology.
  • Although, the majority are nonfunctional, some carcinoids can cause so called classical or atypical carcinoid syndrome and sometimes also paraneoplastic syndromes.
  • Carcinoid tumours often present with metastatic disease.
  • Despite the fact that many advances have been made in both the basic science and clinical areas, the optimal treatment of carcinoid tumours is still a matter of debate.
  • In this article, the pathogenesis, clinical aspects, classification, diagnosis and treatment of carcinoids are reviewed including the latest advances in each area.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Carcinoid Tumor / therapy. Gastrointestinal Neoplasms / diagnosis. Gastrointestinal Neoplasms / therapy
  • [MeSH-minor] Appendiceal Neoplasms / diagnosis. Appendiceal Neoplasms / therapy. Bronchial Neoplasms / diagnosis. Bronchial Neoplasms / therapy. Humans. Rectal Neoplasms / diagnosis. Rectal Neoplasms / therapy

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  • (PMID = 17892042.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 46
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85. Das-Neves-Pereira JC, de Matos LL, Danel C, Trufelli D, Riquet M: Typical bronchopulmonary carcinoid tumors: a ramifying bronchial presentation with metastatic behavior. Ann Thorac Surg; 2006 Dec;82(6):2265-6
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  • [Title] Typical bronchopulmonary carcinoid tumors: a ramifying bronchial presentation with metastatic behavior.
  • Bronchopulmonary typical carcinoid tumors (BTCT) are neuroendocrine neoplasms with histologic low grade characteristics considered benign.
  • Metastasis occurred despite typical carcinoid microscopic features in 3 female patients of African origin presenting at macroscopic examination as ramifying bronchopulmonary typical carcinoid tumors following the bronchial tree.
  • We suggest that clinical ramifying presentation may be related to metastatic behavior, even for bronchopulmonary typical carcinoid tumors not displaying histologic criteria for atypical carcinoid tumors.
  • [MeSH-major] Bronchial Neoplasms / pathology. Carcinoid Tumor / pathology

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  • (PMID = 17126146.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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86. Bednaríková M, Valík D, Vyzula R: [Somatostatin analogues in the treatment of carcinoid]. Cas Lek Cesk; 2008;147(4):233-5
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  • [Title] [Somatostatin analogues in the treatment of carcinoid].
  • The patient--born in 1960, was first diagnosed in 1981 as having malignant carcinoid of the right lung.
  • According to tumor histology--atypical carcinoid--this patient was initially treated with palliative systemic chemotherapy, specifically with cisplatin and etoposid.
  • This case study illustrates the necessity of cautious and individual approach to the choice of treatment strategy in patients with malignant carcinoid.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Carcinoid Tumor / drug therapy. Lung Neoplasms / pathology. Somatostatin / analogs & derivatives

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  • (PMID = 18578378.001).
  • [ISSN] 0008-7335
  • [Journal-full-title] Casopís lékar̆ů c̆eských
  • [ISO-abbreviation] Cas. Lek. Cesk.
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 51110-01-1 / Somatostatin
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87. Zidi A, Douira W, Hantous-Zannad S, Mestiri I, Ben Miled-M'Rad K: [Imaging of bronchial carcinoid tumors: 20 cases]. Rev Pneumol Clin; 2006 Dec;62(6 Pt 1):380-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Imaging of bronchial carcinoid tumors: 20 cases].
  • PURPOSE: Report radiographic aspects and assess the contribution of computed tomography for the diagnosis and search for extension of bronchial carcinoid tumors.
  • MATERIAL AND METHODS: This retrospective study included 20 patients with a bronchial carcinoid tumor.
  • CT revealed secondary ventilatory disorders with no individualized mass in one patients (5%), an isolated parenchymatous mass in two (10%) and a endobronchial budding at the origin of the right bronchus with no noted ventilatory disorder in one patient (5%) Tumor calcifications were detected in 30% of patients.
  • Histological there were 17 typical carcinoid tumors and three atypical tumors which were different by their size, locoregional and distant metastatic spread.
  • CONCLUSION: CT is indispensable for positive diagnosis, and topographic localization of extension of bronchial carcinoid tumors.
  • The main contribution of CT compared with fibroscopy is to demonstrate exobronchial tumor development and upstream pulmonary complications.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Bronchoscopy / methods. Carcinoid Tumor / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 17242643.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] France
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88. Deb SJ, Nichols FC, Allen MS, Deschamps C, Cassivi SD, Pairolero PC: Pulmonary carcinoid tumors with Cushing's syndrome: an aggressive variant or not? Ann Thorac Surg; 2005 Apr;79(4):1132-6; discussion 1132-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary carcinoid tumors with Cushing's syndrome: an aggressive variant or not?
  • BACKGROUND: Adrenocorticotropic hormone (ACTH)-secreting pulmonary carcinoid is considered an aggressive variant of carcinoid tumors.
  • METHODS: All patients with Cushing's syndrome (CS) resulting from pulmonary carcinoid (PC) who underwent pulmonary resection at our institution from November 1966 through April 1998 were reviewed.
  • Chest radiographs identified an abnormality in 13 patients (57%) and chest computerized tomography (CT) identified an abnormality in all 20 patients examined.
  • Typical carcinoid was identified in 21 patients (91%) and atypical carcinoid was identified in 2 patients (9%).
  • The median tumor diameter was 1.3 cm (range: 0.3-10).
  • Although rare these tumors do not seem to be as aggressive a variant of typical carcinoid tumors as previously reported.
  • [MeSH-major] Carcinoid Tumor / surgery. Cushing Syndrome / etiology. Lung Neoplasms / surgery


89. Ricci A, Graziano P, Mariotta S, Cardillo G, Sposato B, Terzano C, Bronzetti E: Neurotrophin system expression in human pulmonary carcinoid tumors. Growth Factors; 2005 Dec;23(4):303-12
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  • [Title] Neurotrophin system expression in human pulmonary carcinoid tumors.
  • Neurotrophin (NT) and NT receptor expression was assessed in 12 typical (TC) and 8 atypical (AC) human pulmonary carcinoids by Western blot and immunohistochemistry.
  • TC and AC carcinoid express to different extent NT and NT receptor proteins.
  • Contrarily to the BDNF/TrkB, expression of the NGF/TrkA signaling may overcome aggressiveness of carcinoid cells.
  • [MeSH-major] Carcinoid Tumor / metabolism. Lung Neoplasms / metabolism. Nerve Growth Factors / biosynthesis

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  • (PMID = 16338793.001).
  • [ISSN] 0897-7194
  • [Journal-full-title] Growth factors (Chur, Switzerland)
  • [ISO-abbreviation] Growth Factors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Brain-Derived Neurotrophic Factor; 0 / Nerve Growth Factors; 0 / Neurotrophin 3; EC 2.7.10.1 / Receptor, trkA; EC 2.7.10.1 / Receptor, trkB; EC 2.7.10.1 / Receptor, trkC
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90. Capovilla M, Kambouchner M, Bernier M, Soulier A, Tissier F, Saintigny P: Late cerebellar relapse of a juvenile bronchial carcinoid. Clin Lung Cancer; 2007 Mar;8(5):339-41
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  • [Title] Late cerebellar relapse of a juvenile bronchial carcinoid.
  • The most frequent histologic subtype is well differentiated neuroendocrine tumor, or carcinoid.
  • They have a variable biologic behavior, ranging from benign to malignant tumors capable of very late recurrence or metastasis.
  • Liver and lung are frequent sites of carcinoid metastasis, and the central nervous system is exceptionally involved.
  • We report the case of a child with a pulmonary carcinoid initially considered typical, who presented with relapse in the cerebellum and mediastinum 16 years later.
  • After review of the pathology slides, primary and metastatic tumors were reclassified as atypical carcinoid according to the criteria of the 2004 World Health Organization classification of lung tumors.
  • This unusual case emphasizes the value of reviewing pulmonary carcinoids diagnosed before 1998 in order to distinguish typical from atypical lesions and to define follow-up modalities more clearly.
  • [MeSH-major] Bronchial Neoplasms / pathology. Carcinoid Tumor / pathology. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / secondary. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / secondary

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  • (PMID = 17562235.001).
  • [ISSN] 1525-7304
  • [Journal-full-title] Clinical lung cancer
  • [ISO-abbreviation] Clin Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Nakamura Y, Sato N, Kaimori K, Imai T: [Thymic carcinoid with lymph node metastases; report of a case]. Kyobu Geka; 2007 Dec;60(13):1204-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Thymic carcinoid with lymph node metastases; report of a case].
  • A 71-year-old man was admitted to our hospital because of the detection of an anterior mediastinal tumor.
  • Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed abnormal accumulations in the tumor and the hilar and the supra-clavicular lymph nodes.
  • Preoperatively, percutaneous needle biopsy of the tumor revealed thymic carcinoid.
  • Tumor resection and thymectomy with mediastinal and supra-clavicular lymph nodes dissection were performed because of suspecting metastasis to the lymph nodes from FDG-PET.
  • Postoperative pathological diagnosis revealed atypical carcinoid and metastases to the mediastinal and supra-clavicular lymph nodes.
  • In our case, FDG-PET was useful in detecting the thymic carcinoid and lymph node metastasis.
  • It is desirable to perform clinical research by many facilities for the assessment of FDG-PET as a diagnostic tool and postoperative chemo-radiation therapy for thymic carcinoid.
  • [MeSH-major] Carcinoid Tumor / pathology. Lymph Nodes / pathology. Lymphatic Metastasis / pathology. Thymus Neoplasms / pathology

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  • (PMID = 18078092.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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92. Onozato Y, Kakizaki S, Iizuka H, Sohara N, Mori M, Itoh H: Endoscopic treatment of rectal carcinoid tumors. Dis Colon Rectum; 2010 Feb;53(2):169-76
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic treatment of rectal carcinoid tumors.
  • BACKGROUND: Various methods have been reported for the endoscopic treatment of rectal carcinoid tumors.
  • METHODS: Forty rectal carcinoid tumors of 38 patients were treated endoscopically.
  • All tumors were estimated to measure 1 cm or less in diameter, without muscular invasion, atypical features, and lymph node metastases to the pararectal region.
  • CONCLUSIONS: Small carcinoid tumors measuring less than 1 cm in diameter can therefore be managed endoscopically with no recurrence or spread.
  • [MeSH-major] Carcinoid Tumor / surgery. Colonoscopy / methods. Rectal Neoplasms / surgery

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  • [CommentIn] Dis Colon Rectum. 2012 Aug;55(8):e320 [22810480.001]
  • (PMID = 20087092.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] United States
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93. Belak J, Kudlac M, Zak V, Cavarga I, Kocan P, Böör A, Stebnicky M, Somos A, Tkacova R: Surgical management of bronchopulmonary carcinoid tumors: experience over 8 years and review of the literature. Tumori; 2010 Jan-Feb;96(1):84-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of bronchopulmonary carcinoid tumors: experience over 8 years and review of the literature.
  • Our purpose was to study the characteristics, surgical approaches and outcome in patients with primary bronchopulmonary carcinoid tumors.
  • METHODS: Between 2001 and 2007, bronchopulmonary carcinoid tumors were removed in 11 of a total of 287 patients who underwent surgery for primary lung malignancies in our tertiary referral center.
  • Histological findings revealed typical carcinoid in 10 patients and atypical carcinoid in one.
  • The surgical approach included 8 lung resections (6 lobectomies, 1 bilobectomy, 1 segmentectomy), and 3 bronchoplastic tumor removals.
  • In 2008, clinical examination and chest X-ray revealed no recurrence of the carcinoid and no long-term postoperative complications in any patient.
  • CONCLUSIONS: In the light of our study and the review of the literature we conclude that early recognition of primary bronchopulmonary carcinoid tumors followed by adequate surgical removal of the malignancy are essential for complete remission of the disease.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Bronchial Neoplasms / surgery. Carcinoid Tumor / diagnosis. Carcinoid Tumor / surgery. Lung Neoplasms / diagnosis. Lung Neoplasms / surgery

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  • (PMID = 20437863.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Italy
  • [Number-of-references] 29
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94. Daniels CE, Lowe VJ, Aubry MC, Allen MS, Jett JR: The utility of fluorodeoxyglucose positron emission tomography in the evaluation of carcinoid tumors presenting as pulmonary nodules. Chest; 2007 Jan;131(1):255-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The utility of fluorodeoxyglucose positron emission tomography in the evaluation of carcinoid tumors presenting as pulmonary nodules.
  • BACKGROUND: Fluorodeoxyglucose positron emission tomography (FDG-PET) is sensitive for detection of neoplastic solitary pulmonary nodules but may have decreased sensitivity for detection of carcinoid tumors.
  • Our purpose was to determine the sensitivity of FDG-PET to detect pulmonary carcinoid tumors.
  • METHODS: We performed a retrospective review of our institutional results regarding FDG-PET in the setting of thoracic carcinoid neoplasms.
  • We identified 16 patients with a pathologic diagnosis of bronchial carcinoid who had an antecedent FDG-PET (from 2000 to 2004).
  • RESULTS: Sixteen patients had a diagnosis of carcinoid tumor, typical in 11 patients and atypical in 5 patients.
  • CONCLUSIONS: FDG-PET imaging is useful for evaluation of typical and atypical thoracic carcinoid tumors.
  • Although overall PET sensitivity for detection of carcinoid tumors is somewhat reduced as compared to non-small cell lung cancer, it is much higher than prior reports suggest.
  • [MeSH-major] Carcinoid Tumor / radionuclide imaging. Carcinoma, Non-Small-Cell Lung / radionuclide imaging. Fluorodeoxyglucose F18. Lung Neoplasms / radionuclide imaging. Positron-Emission Tomography. Radiopharmaceuticals. Solitary Pulmonary Nodule / radionuclide imaging

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  • (PMID = 17218584.001).
  • [ISSN] 0012-3692
  • [Journal-full-title] Chest
  • [ISO-abbreviation] Chest
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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95. Dutta R, Kumar A, Julka PK, Mathur SR, Kaushal S, Kumar R, Jindal T, Suri V: Thymic neuroendocrine tumour (carcinoid): clinicopathological features of four patients with different presentation. Interact Cardiovasc Thorac Surg; 2010 Dec;11(6):732-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thymic neuroendocrine tumour (carcinoid): clinicopathological features of four patients with different presentation.
  • This article describes the utility of (68)Gallium-1,4,7,10-traazacyclododecane-NI, NII, NIII, NIIII-tetra acetic acid-(D)-Phel1-Tyr3-octreotide positron emission tomography ((68)Ga DOTATOC PET-CT-scan) and clinicopathological features of four thymic carcinoid tumours.
  • Two typical, one atypical, and one large cell neuroendocrine carcinoma (LCNEC) were analysed.
  • Three patients had a stage III and one had a stage II tumour.
  • Preoperative (68)Ga DOTATOC PET-CT-scan of three patients did not show uptake of radiotracer in the tumour.
  • There is no locoregional recurrence of tumour in any of our patients.
  • Complete surgical resection of the tumour with invaded adjacent structures, postoperative radiotherapy to the tumour bed helps in obtaining disease free survival.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Octreotide / analogs & derivatives. Organometallic Compounds. Positron-Emission Tomography. Radiopharmaceuticals. Thymus Neoplasms / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 20851876.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Ga(III)-DOTATOC; 0 / Organometallic Compounds; 0 / Radiopharmaceuticals; RWM8CCW8GP / Octreotide
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96. Nogales FF, Buriticá C, Regauer S, González T: Mucinous carcinoid as an unusual manifestation of endodermal differentiation in ovarian yolk sac tumors. Am J Surg Pathol; 2005 Sep;29(9):1247-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucinous carcinoid as an unusual manifestation of endodermal differentiation in ovarian yolk sac tumors.
  • We present, for the first time, two yolk sac tumors (YST) in women 37 and 18 years of age, one with a typical parietovisceral pattern and the other with a glandular pattern, which were associated with extensive areas of mucinous carcinoid (MC).
  • The tumor in the first case had numerous nodules of tubulopapillary YST that merged with well-differentiated MC.
  • The tumor in the second case consisted of an AFP-positive glandular YST, with a glandulopapillary pattern closely resembling fetal lung type adenocarcinoma, coexisting with an AFP-negative, cytokeratin 20-positive, atypical MC; transitional areas between the two components were also seen.
  • In the material from the recurrences and metastases; however, no YST was present, the atypical MC having become the predominant component including areas that had become carcinomatous.
  • The patient died 1 year after diagnosis.
  • It is important to differentiate the yolk sac and carcinoid components due to their different responses to chemotherapy and to evaluate the possibility of mucinous carcinoid developing into a highly aggressive carcinoma.
  • [MeSH-major] Carcinoid Tumor / pathology. Endodermal Sinus Tumor / pathology. Ovarian Neoplasms / drug therapy

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  • (PMID = 16096416.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / alpha-Fetoproteins
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97. Rea F, Rizzardi G, Zuin A, Marulli G, Nicotra S, Bulf R, Schiavon M, Sartori F: Outcome and surgical strategy in bronchial carcinoid tumors: single institution experience with 252 patients. Eur J Cardiothorac Surg; 2007 Feb;31(2):186-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Outcome and surgical strategy in bronchial carcinoid tumors: single institution experience with 252 patients.
  • OBJECTIVE: To evaluate type of surgery, long-term survival and factors influencing outcome in pulmonary carcinoid tumors.
  • PATIENTS AND METHODS: We reviewed data of 252 patients who underwent surgery for carcinoid tumor in 1968-1989 (Group A) and in 1990-2005 (Group B).
  • All cases were reviewed and classified as typical (TC) or atypical carcinoid (AC) according to WHO criteria (1999).
  • CONCLUSIONS: Typical histology and N0 status were important prognostic factors in carcinoid tumors.
  • [MeSH-major] Bronchial Neoplasms / surgery. Carcinoid Tumor / surgery

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  • (PMID = 17140801.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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98. Mackley HB, Videtic GM: Primary carcinoid tumors of the lung: a role for radiotherapy. Oncology (Williston Park); 2006 Nov;20(12):1537-43; discussion 1544-5, 1549
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary carcinoid tumors of the lung: a role for radiotherapy.
  • Primary neuroendocrine neoplasms of the lung represent a clinical spectrum of tumors ranging from the relatively benign and slow-growing typical carcinoid to the highly aggressive small-cell lung carcinoma.
  • Resected atypical carcinoids and large-cell neuroendocrine carcinomas have a significant risk of localfailure, for which adjuvant radiation likely improves local control.
  • [MeSH-major] Carcinoid Tumor / radiotherapy. Lung Neoplasms / radiotherapy. Neoplasm Recurrence, Local / radiotherapy

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  • (PMID = 17153907.001).
  • [ISSN] 0890-9091
  • [Journal-full-title] Oncology (Williston Park, N.Y.)
  • [ISO-abbreviation] Oncology (Williston Park, N.Y.)
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 50
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99. Wong M, Isa SH, Kamaruddin NA, Khalid BA: ACTH producing pulmonary carcinoid and pituitary macroadenoma: a fortuitous association? Med J Malaysia; 2007 Jun;62(2):168-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] ACTH producing pulmonary carcinoid and pituitary macroadenoma: a fortuitous association?
  • Histological examination revealed an atypical carcinoid.
  • To our knowledge, this is the first reported case of an ectopic ACTH secreting pulmonary carcinoid found in association with a non-functioning pituitary macroadenoma.
  • [MeSH-major] ACTH Syndrome, Ectopic / complications. Carcinoid Tumor / secretion. Lung Neoplasms / secretion. Pituitary Neoplasms / complications

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  • (PMID = 18705457.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Malaysia
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100. Karavolos S, Caplin M, Benjamin E, Crow J, Mould T: Primary mucinous carcinoid tumour of the ovary: a case report. Eur J Gynaecol Oncol; 2006;27(6):618-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mucinous carcinoid tumour of the ovary: a case report.
  • Primary ovarian carcinoid tumours of the ovary are rare and represent less than 0.1% of ovarian malignancy.
  • We report a case of primary ovarian mucinous carcinoid tumour, of the atypical category, in a 34-year-old nulliparous woman.
  • This case adds to the body of evidence and demonstrates a possible good prognosis with non-aggressive behaviour in the atypical mucinous carcinoid group.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoid Tumor / surgery. Ovarian Neoplasms / surgery
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Leiomyoma / diagnosis. Prognosis. Treatment Outcome

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  • (PMID = 17290597.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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