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1. Krutsay M, Sipos G: [Gliomatosis cerebri]. Magy Onkol; 2006;50(1):55-8
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  • [Title] [Gliomatosis cerebri].
  • [Transliterated title] Gliomatosis cerebri.
  • The histologic examination revealed gliomatosis cerebri of the white matter of the cerebral hemispheres.

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  • (PMID = 16617385.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Hungary
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2. D'Urso OF, D'Urso PI, Marsigliante S, Storelli C, Luzi G, Gianfreda CD, Montinaro A, Distante A, Ciappetta P: Correlative analysis of gene expression profile and prognosis in patients with gliomatosis cerebri. Cancer; 2009 Aug 15;115(16):3749-57
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  • [Title] Correlative analysis of gene expression profile and prognosis in patients with gliomatosis cerebri.
  • The authors investigated whether gene expression profiling, coupled with class prediction methodology, could be used to determine the prognosis of gliomatosis cerebri in a more consistent manner than standard pathology.
  • RESULTS: The authors reported the results of a molecular study in 59 cases of gliomatosis cerebri, correlating these results with prognosis.


3. Val Filho JA, Avelar LG: Gliomatosis cerebri with favorable outcome in a child: a case report. J Pediatr (Rio J); 2008 Sep-Oct;84(5):463-6
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  • [Title] Gliomatosis cerebri with favorable outcome in a child: a case report.
  • OBJECTIVE: To report a rare clinical case of gliomatosis cerebri with favorable outcome in a 3-year old child.
  • DESCRIPTION: A 3-year old child developed severe and progressive symptoms of gliomatosis cerebri.
  • COMMENTS: The child's clinical presentation and the combination of symptoms led to the diagnosis of gliomatosis cerebri.

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  • [CommentIn] J Pediatr (Rio J). 2009 May-Jun;85(3):277-9; author reply 279-80 [19492175.001]
  • (PMID = 18833342.001).
  • [ISSN] 1678-4782
  • [Journal-full-title] Jornal de pediatria
  • [ISO-abbreviation] J Pediatr (Rio J)
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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4. Seiz M, Kohlhof P, Brockmann MA, Neumaier-Probst E, Hermes P, VON Deimling A, Vajkoczy P, Schmieder K, Tuettenberg J: First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity. Anticancer Res; 2009 Aug;29(8):3261-7
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  • [Title] First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity.
  • BACKGROUND: Gliomatosis cerebri is a rare primary cerebral tumour entity characterized by diffuse infiltrative growth patterns representing a WHO grade III malignancy.
  • In contrast to other high-grade gliomas, angiogenesis is thought to be absent in gliomatosis cerebri.
  • PATIENTS AND METHODS: Despite this assumption, histopathological analyses of samples of six patients with gliomatosis cerebri were performed and surprisingly there was angiogenic activity with expression of vascular endothelial growth factor and cyclooxygenase 2.
  • CONCLUSION: From our initial experience in a small number of patients with gliomatosis cerebri with signs of angiogenic activity, we conclude that low-dose chemotherapy might provide a promising approach for treatment of these patients and that overexpression of angiogenic factors such as VEGF or COX-2 seems to be more frequent than hitherto reported.

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  • (PMID = 19661344.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Pyrazoles; 0 / Sulfonamides; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human; JCX84Q7J1L / Celecoxib
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5. Gruber A, Leschnik M, Kneissl S, Schmidt P: Gliomatosis cerebri in a dog. J Vet Med A Physiol Pathol Clin Med; 2006 Oct;53(8):435-8
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  • [Title] Gliomatosis cerebri in a dog.
  • Gliomatosis cerebri is a rare tumourous disease of the central nervous system consisting of glial cells characterized by diffuse widespread infiltration and preservation of preformed brain structures.
  • This report describes a case of gliomatosis cerebri in a 9-year-old, male, flat-coated retriever dog with central nervous symptoms.
  • Magnetic resonance imaging of the brain demonstrated ill-defined hyperintense zones of paramedian white matter within the right cerebral hemisphere, brainstem and cerebellum.
  • Based on these findings, the alteration was diagnosed as gliomatosis cerebri.

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  • (PMID = 16970635.001).
  • [ISSN] 0931-184X
  • [Journal-full-title] Journal of veterinary medicine. A, Physiology, pathology, clinical medicine
  • [ISO-abbreviation] J Vet Med A Physiol Pathol Clin Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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6. Ware ML, Hirose Y, Scheithauer BW, Yeh RF, Mayo MC, Smith JS, Chang S, Cha S, Tihan T, Feuerstein BG: Genetic aberrations in gliomatosis cerebri. Neurosurgery; 2007 Jan;60(1):150-8; discussion 158
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  • [Title] Genetic aberrations in gliomatosis cerebri.
  • OBJECTIVE: Identifying the genetic alterations in gliomatosis cerebri (GC) may yield clinically useful prognostic markers and provide clues as to whether GC represents a distinct pathological entity or is an extreme form of diffusely infiltrative glioma.

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  • (PMID = 17228264.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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7. Knox MK, Ménard C, Mason WP: Leptomeningeal gliomatosis as the initial presentation of gliomatosis cerebri. J Neurooncol; 2010 Oct;100(1):145-9
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  • [Title] Leptomeningeal gliomatosis as the initial presentation of gliomatosis cerebri.
  • Leptomeningeal gliomatosis is a known, yet uncommon, complication of malignant gliomas.
  • Gliomatosis cerebri is also a rare disease, characterized by extensive diffuse infiltration of neoplastic glial cells.
  • The diagnosis of gliomatosis cerebri with diffuse leptomeningeal gliomatosis was established in hindsight.

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  • (PMID = 20146082.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Ellingson BM, Rand SD, Malkin MG, Schmainda KM: Utility of functional diffusion maps to monitor a patient diagnosed with gliomatosis cerebri. J Neurooncol; 2010 May;97(3):419-23
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  • [Title] Utility of functional diffusion maps to monitor a patient diagnosed with gliomatosis cerebri.
  • In this case study we demonstrate the utility of applying fDMs to regions of abnormal FLAIR signal intensity in a patient diagnosed with gliomatosis cerebri: a relatively rare, infiltrative, non-enhancing brain tumor.

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  • (PMID = 19813078.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R21 CA109280-02; United States / NCI NIH HHS / CA / R21 CA109280; United States / NCI NIH HHS / CA / CA109280-02; United States / NCI NIH HHS / CA / R21 CA109820; United States / NCI NIH HHS / CA / R01 CA109820
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS241539; NLM/ PMC2956408
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9. Kaloshi G, Everhard S, Laigle-Donadey F, Marie Y, Navarro S, Mokhtari K, Idbaih A, Ducray F, Thillet J, Hoang-Xuan K, Delattre JY, Sanson M: Genetic markers predictive of chemosensitivity and outcome in gliomatosis cerebri. Neurology; 2008 Feb 19;70(8):590-5
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  • [Title] Genetic markers predictive of chemosensitivity and outcome in gliomatosis cerebri.
  • BACKGROUND: Up-front temozolomide (TMZ) has been recently proposed as a treatment for gliomatosis cerebri (GC), but no predictive or prognostic markers have been identified so far.
  • The impact of methylguanine methyl transferase promoter methylation status on gliomatosis cerebri is still unsettled in this population.

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  • (PMID = 18285534.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Biomarkers, Tumor; 0 / Genetic Markers; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide; EC 2.1.1.63 / O(6)-Methylguanine-DNA Methyltransferase
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10. Uysal E, Erturk M, Yildirim H, Karatag O, Can M, Tanik C, Basak M: Multivoxel magnetic resonance spectroscopy in gliomatosis cerebri. Acta Radiol; 2005 Oct;46(6):621-4
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  • [Title] Multivoxel magnetic resonance spectroscopy in gliomatosis cerebri.
  • Gliomatosis cerebri is a rare entity with non-specific clinical and conventional magnetic resonance imaging (MRI) findings; accurate diagnosis is a differential diagnostic challenge.
  • We present a gliomatosis cerebri case in which we made the radiological diagnosis using the MR spectroscopy findings; the diagnosis was confirmed by subsequent biopsy and histopathologic evaluation.

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  • (PMID = 16334845.001).
  • [ISSN] 0284-1851
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 30KYC7MIAI / Aspartic Acid; 997-55-7 / N-acetylaspartate; MU72812GK0 / Creatine; N91BDP6H0X / Choline
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11. Kaloshi G, Guillevin R, Martin-Duverneuil N, Laigle-Donadey F, Psimaras D, Marie Y, Mokhtari K, Hoang-Xuan K, Delattre JY, Sanson M: Gray matter involvement predicts chemosensitivity and prognosis in gliomatosis cerebri. Neurology; 2009 Aug 11;73(6):445-9
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  • [Title] Gray matter involvement predicts chemosensitivity and prognosis in gliomatosis cerebri.
  • BACKGROUND: In gliomatosis cerebri (GC), defined as a diffuse neoplastic glial cell infiltration of the brain, upfront chemotherapy is often proposed as an alternative to radiotherapy.
  • CONCLUSION: These data suggest that gray matter index is a prognostic and predictive marker in gliomatosis cerebri that may in part depend on the 1p/19q status.
  • [MeSH-major] Cerebral Cortex / pathology. Neoplasms, Neuroepithelial / diagnosis. Neoplasms, Neuroepithelial / drug therapy

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  • (PMID = 19667319.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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12. Mawrin C, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Deimling A, Stoltenburg-Didinge G, Bornemann A, Romeike B, Sellhaus B, Dietzmann K: Alterations of cell cycle regulators in gliomatosis cerebri. J Neurooncol; 2005 Apr;72(2):115-22
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  • [Title] Alterations of cell cycle regulators in gliomatosis cerebri.
  • Gliomatosis cerebri (GC) is regarded as a rare glial neoplasm of unknown origin, and a detailed analysis of molecular alterations underlying this disease has started only recently.
  • Moreover, the detected aberrations in gliomatosis cerebri can reflect the tumor progression associated with secondary malignant astrocytoma formation even within a single case.

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  • (PMID = 15925990.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Nuclear Proteins; 0 / Proto-Oncogene Proteins; 9007-49-2 / DNA; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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13. Pal L, Behari S, Kumar S, Kumar R, Shankar SK, Gupta RK: Gliomatosis cerebri--an uncommon neuroepithelial tumor in children with oligodendroglial phenotype. Pediatr Neurosurg; 2008;44(3):212-5
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  • [Title] Gliomatosis cerebri--an uncommon neuroepithelial tumor in children with oligodendroglial phenotype.
  • Gliomatosis cerebri(GC) is a highly aggressive, rare form of neuroepithelial tumor.
  • In view of the rarity of the oligodendroglial phenotype of gliomatosis cerebri as well as the rare occurrence in children, we report these 2 cases.

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  • (PMID = 18334846.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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14. Soffietti R, Rudà R, Trevisan E, Picco E, Guarneri D, Caroli M, Fabrini M, Scotti V: Phase II study of bevacizumab and nitrosourea in patients with recurrent malignant glioma: A multicenter Italian study. J Clin Oncol; 2009 May 20;27(15_suppl):2012

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  • Patterns of progression were local in 10/16, local + leptomeningeal spread in 3/16 and gliomatosis in 3/16.

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  • (PMID = 27964590.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Yu A, Li K, Li H: Value of diagnosis and differential diagnosis of MRI and MR spectroscopy in gliomatosis cerebri. Eur J Radiol; 2006 Aug;59(2):216-21
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  • [Title] Value of diagnosis and differential diagnosis of MRI and MR spectroscopy in gliomatosis cerebri.
  • PURPOSE: The purpose of this study was to characterize gliomatosis cerebri on magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), and to analyze the value of these two techniques in diagnosis and differential diagnosis of gliomatosis cerebri.
  • MATERIALS AND METHODS: MR images of 14 patients with gliomatosis cerebri were reviewed retrospectively; seven of the patients also underwent MRS (single-voxel point-resolved spectroscopy, and chemical-shift imaging point-resolved spectroscopy).
  • Abnormality of metabolism was also seen in the margin of the lesion that was normal on T2-weighted images.
  • CONCLUSION: MRI and MRS are valuable techniques for diagnosis and differential diagnosis of gliomatosis cerebri.

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  • (PMID = 16769190.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Ireland
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21. Inoue T, Kanamori M, Sonoda Y, Watanabe M, Sasajima T, Kamisato N, Kumabe T, Tominaga T: [Glioblastoma multiforme developing separately from the initial lesion 9 years after successful treatment for gliomatosis cerebri: a case report]. No Shinkei Geka; 2008 Aug;36(8):709-15
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  • [Title] [Glioblastoma multiforme developing separately from the initial lesion 9 years after successful treatment for gliomatosis cerebri: a case report].
  • Gliomatosis cerebri is a diffuse growth pattern of glioma consisting of exceptionally extensive infiltration of at least three cerebral lobes.
  • We report a case of histologically confirmed glioblastoma multiforme in the cerebellar vermis which occurred 9 years after treatment for gliomatosis cerebri.
  • Histological examination of biopsy specimens from the left frontal lobe lesion demonstrated diffuse infiltration of glial neoplastic cells with preservation of the underlying cytoarchitecture, leading to the diagnosis of gliomatosis cerebri.
  • This case suggests that glioblastoma multiforme could develop in the long term after initial treatment for gliomatosis cerebri, and in a location separate from the initial lesion.

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  • (PMID = 18700534.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 12
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22. Kong DS, Kim ST, Lee JI, Suh YL, Lim DH, Kim WS, Kwon KH, Park K, Kim JH, Nam DH: Impact of adjuvant chemotherapy for gliomatosis cerebri. BMC Cancer; 2010;10:424
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  • [Title] Impact of adjuvant chemotherapy for gliomatosis cerebri.
  • BACKGROUND: Gliomatosis cerebri (GC) is characterized by a diffuse infiltration of tumor cells throughout CNS, however, few details are available about the chemotherapeutic effect on GC.

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  • (PMID = 20704759.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 35S93Y190K / Procarbazine; 5J49Q6B70F / Vincristine; 7BRF0Z81KG / Lomustine; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide; U68WG3173Y / Carmustine
  • [Other-IDs] NLM/ PMC2933624
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23. Hilbig A, Barbosa-Coutinho LM, Toscani N, Ribeiro Mde C, da Cunha BS: Expression of nestin and vimentin in gliomatosis cerebri. Arq Neuropsiquiatr; 2006 Sep;64(3B):781-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of nestin and vimentin in gliomatosis cerebri.
  • Gliomatosis cerebri (GC) is a rare form of CNS neoplasia in which there is diffuse involvement of the nervous tissue with or without the presence of tumor mass.

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  • (PMID = 17057885.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin; 0 / Synaptophysin; 0 / Vimentin
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24. Jimenez Caballero PE, Mollejo Villanueva M, Marsal Alonso C: [Gliomatosis cerebri: evolution to glioblastoma multiforme]. Neurologia; 2007 Jul-Aug;22(6):395-8
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  • [Title] [Gliomatosis cerebri: evolution to glioblastoma multiforme].
  • [Transliterated title] Gliomatosis cerebri: evolución a glioblastoma multiforme.
  • INTRODUCTION: Gliomatosis cerebri is a neoplastic disorder characterized by diffuse infiltration of glial cells with relative conservation of the underlying structures.
  • The brain magnetic resonance imaging showed hyperintense lesions in T2 suggestive of gliomatosis cerebri, this being confirmed with the brain biopsy.
  • CONCLUSIONS: In spite of its rareness, gliomatosis cerebri should be taken into account in the differential diagnoses of diffuse infiltrative lesions of the white matter.

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  • (PMID = 17610168.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 25
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25. Suzuki T, Izumoto S, Fujimoto Y, Maruno M, Ito Y, Yoshimine T: Clinicopathological study of cellular proliferation and invasion in gliomatosis cerebri: important role of neural cell adhesion molecule L1 in tumour invasion. J Clin Pathol; 2005 Feb;58(2):166-71
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  • [Title] Clinicopathological study of cellular proliferation and invasion in gliomatosis cerebri: important role of neural cell adhesion molecule L1 in tumour invasion.
  • BACKGROUND/AIMS: In patients with gliomatosis cerebri (GC), glial fibrillary acidic protein (GFAP) positive cells invade the entire brain, particularly the white matter.

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  • (PMID = 15677537.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / Neural Cell Adhesion Molecule L1
  • [Other-IDs] NLM/ PMC1770574
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26. San Millan B, Kaci R, Polivka M, Robert G, Héran F, Gueguen A, Mokhtari K, Gray F: [Gliomatosis cerebri: a biopsy and autopsy case report]. Ann Pathol; 2010 Feb;30(1):25-9
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  • [Title] [Gliomatosis cerebri: a biopsy and autopsy case report].
  • [Transliterated title] Gliomatose cérébrale diffuse: étude biopsique et autopsique d'un cas.
  • Gliomatosis cerebri is a rare glial neoplasm, characterized by diffuse brain infiltration with relative preservation of the underlying cytoarchitecture.
  • We report a case of gliomatosis cerebri in a 68-year-old woman presenting with gait disturbances and episodic seizures.
  • Postmortem brain examination confirmed gliomatosis cerebri and revealed a focal glioblastoma in the frontal cortex, with nuclear p53 expression in the highest malignant areas.
  • Gliomatosis cerebri should be included in the differential diagnostic of diffuse brain lesions.

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  • [Copyright] Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20223351.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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27. Bruna J, Velasco R: [Gliomatosis cerebri]. Neurologia; 2010 Apr;25(3):143-7
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  • [Title] [Gliomatosis cerebri].
  • [Transliterated title] Gliomatosis cerebri.
  • INTRODUCTION: gliomatosis cerebri (GC) is a rare, diffusely growing glial tumour characterized by extensive brain infiltration.

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  • [Copyright] Published by Elservier España, S.L. All rights reserved.
  • (PMID = 20492859.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Editorial; English Abstract
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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28. Gleizniene R, Bucinskas U, Lukosevicius S, Vaitkus A, Letautiene S, Apanaviciūte D, Galvonaite M: Gliomatosis cerebri. Medicina (Kaunas); 2010;46(5):341-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri.
  • Gliomatosis cerebri is a rare diffusely infiltrating glial tumor involving two or more lobes and is frequently is bilateral.
  • We present a case in which finally the diagnosis of gliomatosis cerebri was made.
  • Diagnosis of gliomatosis cerebri was suspected, stereotaxic biopsy was performed, and pathological examination revealed changes typical of diffuse glial tumor.
  • In this article, changes typical of gliomatosis cerebri seen in other radiological methods such as computed tomography, magnetic resonance spectroscopy, dynamic contrast-enhanced T2*-weighted magnetic resonance, and positron emission tomography also are discussed.

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  • (PMID = 20679750.001).
  • [ISSN] 1648-9144
  • [Journal-full-title] Medicina (Kaunas, Lithuania)
  • [ISO-abbreviation] Medicina (Kaunas)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Lithuania
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones
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29. Min HS, Kim B, Park SH: Array-based comparative genomic hybridization and immunohistochemical studies in gliomatosis cerebri. J Neurooncol; 2008 Dec;90(3):259-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Array-based comparative genomic hybridization and immunohistochemical studies in gliomatosis cerebri.
  • Gliomatosis cerebri (GC) are extensively infiltrative glial tumors classified as astrocytic tumors in the current World Health Organization (WHO) classification scheme.

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  • (PMID = 18704270.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Glial Fibrillary Acidic Protein; 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin; 0 / Tumor Suppressor Proteins; EC 2.1.1.- / DNA Modification Methylases; EC 2.1.1.63 / MGMT protein, human; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 6.5.1.- / DNA Repair Enzymes
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30. Caroli E, Orlando ER, Ferrante L: Gliomatosis cerebri in children. Case report and clinical considerations. Childs Nerv Syst; 2005 Nov;21(11):1000-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri in children. Case report and clinical considerations.
  • OBJECTIVE: Gliomatosis cerebri (GC) is an uncommon entity characterised by the diffuse overgrowth of large parts of the brain by glial cells.
  • [MeSH-minor] Arachnoid Cysts / diagnosis. Arachnoid Cysts / pathology. Astrocytes / pathology. Biomarkers, Tumor / analysis. Biopsy. Brain / pathology. Cerebral Cortex / pathology. Cerebral Ventricles / pathology. Child. Diagnosis, Differential. Disease Progression. Fatal Outcome. Glial Fibrillary Acidic Protein / analysis. Humans. Ki-67 Antigen / analysis. Male

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  • (PMID = 16240166.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen
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31. Novillo López ME, Gómez-Ibáñez A, Rosenfeld M, Dalmau J: [Gliomatosis cerebri: review of 22 patients]. Neurologia; 2010 Apr;25(3):168-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Gliomatosis cerebri: review of 22 patients].
  • [Transliterated title] Gliomatosis cerebral: estudio de 22 pacientes.
  • INTRODUCTION: gliomatosis cerebri is a diffuse astrocytic neoplasm that involves more than two lobes of the brain.
  • METHODS: retrospective analysis of 22 patients with gliomatosis cerebri.
  • CONCLUSIONS: gliomatosis cerebri has a variable clinical course.

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  • [Copyright] Published by Elservier España, S.L. All rights reserved.
  • (PMID = 20492863.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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32. Maton B, Resnick T, Jayakar P, Morrison G, Duchowny M: Epilepsy surgery in children with gliomatosis cerebri. Epilepsia; 2007 Aug;48(8):1485-90
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  • [Title] Epilepsy surgery in children with gliomatosis cerebri.
  • PURPOSE: Gliomatosis cerebri (GC) is a rare neoplastic disorder that may present as intractable epilepsy during early life.
  • [MeSH-major] Cerebral Cortex / surgery. Epilepsy / surgery. Neoplasms, Neuroepithelial / surgery

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  • (PMID = 17565595.001).
  • [ISSN] 0013-9580
  • [Journal-full-title] Epilepsia
  • [ISO-abbreviation] Epilepsia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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33. Glas M, Rasch K, Wiewrodt D, Weller M, Herrlinger U: Procarbazine and CCNU as initial treatment in gliomatosis cerebri. Oncology; 2008;75(3-4):182-5
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  • [Title] Procarbazine and CCNU as initial treatment in gliomatosis cerebri.
  • BACKGROUND: Gliomatosis cerebri (GC) is a diffuse infiltrating glial tumor with involvement of at least 3 cerebral lobes.

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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18841032.001).
  • [ISSN] 1423-0232
  • [Journal-full-title] Oncology
  • [ISO-abbreviation] Oncology
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 35S93Y190K / Procarbazine; 7BRF0Z81KG / Lomustine
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34. Sharma S, Kalra V, Garg A, Suri V, Suri A: Gliomatosis cerebri. Indian J Pediatr; 2009 May;76(5):553-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri.
  • MRI revealed diffuse signal change and swelling of the left cerebral hemisphere.
  • The diagnosis of gliomatosis cerebri was confirmed by brain biopsy.

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  • (PMID = 19390795.001).
  • [ISSN] 0973-7693
  • [Journal-full-title] Indian journal of pediatrics
  • [ISO-abbreviation] Indian J Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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35. Galán A, Guil-Luna S, Millán Y, Martín-Suárez EM, Pumarola M, de Las Mulas JM: Oligodendroglial gliomatosis cerebri in a poodle. Vet Comp Oncol; 2010 Dec;8(4):254-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oligodendroglial gliomatosis cerebri in a poodle.
  • Gliomatosis cerebri (GC) is a rare, diffusely infiltrating, glial cell tumour of neuroepithelial origin.
  • Histologically there was an infiltration of round or ovoid neoplastic cells in the white matter of the left cerebral hemisphere and in leptomeninges.

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  • [Copyright] © 2010 Blackwell Publishing Ltd.
  • (PMID = 21062407.001).
  • [ISSN] 1476-5829
  • [Journal-full-title] Veterinary and comparative oncology
  • [ISO-abbreviation] Vet Comp Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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36. Inoue T, Kumabe T, Kanamori M, Sonoda Y, Watanabe M, Tominaga T: Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases. Neurosurg Rev; 2010 Apr;34(2):197-208
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  • [Title] Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
  • Gliomatosis cerebri (GC) is a rare fatal glial neoplasm of the central nervous system.

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  • (PMID = 21301914.001).
  • [ISSN] 1437-2320
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Antineoplastic Agents, Alkylating; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53; 0S726V972K / Nimustine; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide; EC 2.1.1.63 / O(6)-Methylguanine-DNA Methyltransferase
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37. Mawrin C: Molecular genetic alterations in gliomatosis cerebri: what can we learn about the origin and course of the disease? Acta Neuropathol; 2005 Dec;110(6):527-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular genetic alterations in gliomatosis cerebri: what can we learn about the origin and course of the disease?
  • Gliomatosis cerebri (GC) is a neuroepithelial neoplasm with extensive infiltration of large parts of the brain.

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  • (PMID = 16222524.001).
  • [ISSN] 0001-6322
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 61
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38. Megdiche H, Zouaoui W, Baccar A, Sebai R, Soukri I, Belghith L, Touibi S: [Gliomatosis cerebri]. Tunis Med; 2006 Dec;84(12):821-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Gliomatosis cerebri].
  • [Transliterated title] La gliomatose cerebrale.
  • The Gliomatosis Cerebri (GC) is an infiltrating and rare primitive tumour of the brain.

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  • (PMID = 17288290.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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39. Akai H, Mori H, Aoki S, Masutani Y, Kawahara N, Shibahara J, Ohtomo K: Diffusion tensor tractography of gliomatosis cerebri: fiber tracking through the tumor. J Comput Assist Tomogr; 2005 Jan-Feb;29(1):127-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diffusion tensor tractography of gliomatosis cerebri: fiber tracking through the tumor.

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  • (PMID = 15665698.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Mawrin C, Schneider T, Firsching R, Wiedemann FR, Dietzmann K, Bornemann A, Romeike BF, Sellhaus B, von Deimling A: Assessment of tumor cell invasion factors in gliomatosis cerebri. J Neurooncol; 2005 Jun;73(2):109-15
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  • [Title] Assessment of tumor cell invasion factors in gliomatosis cerebri.
  • Gliomatosis cerebri (GC) is a rare brain tumor characterized by widespread infiltration of large parts of the brain and sometimes even the spinal cord.

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  • (PMID = 15981099.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Receptors, Fibroblast Growth Factor; 0 / Tenascin; 94ZLA3W45F / Arginine; EC 2.7.10.1 / FGFR4 protein, human; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 4; EC 3.4.24.35 / Matrix Metalloproteinase 9
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41. Nagata R, Ikeda K, Nakamura Y, Ishikawa Y, Miura K, Sato R, Kawase Y, Kawabe K, Iwasaki Y: A case of gliomatosis cerebri mimicking limbic encephalitis: malignant transformation to glioblastoma. Intern Med; 2010;49(13):1307-10
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  • [Title] A case of gliomatosis cerebri mimicking limbic encephalitis: malignant transformation to glioblastoma.
  • Gliomatosis cerebri (GC) is a specific entity defined as diffuse infiltration of neoplastic glial cells into at least three cerebral lobes and preservation of the surrounding neuronal architecture.
  • Cerebral angiography exhibited no tumor stains.


42. Seiz M, Tuettenberg J, Meyer J, Essig M, Schmieder K, Mawrin C, von Deimling A, Hartmann C: Detection of IDH1 mutations in gliomatosis cerebri, but only in tumors with additional solid component: evidence for molecular subtypes. Acta Neuropathol; 2010 Aug;120(2):261-7
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  • [Title] Detection of IDH1 mutations in gliomatosis cerebri, but only in tumors with additional solid component: evidence for molecular subtypes.
  • The current WHO classification of brain tumors defines gliomatosis cerebri (GC) as an extensively infiltrating astrocytic glioma involving at least three cerebral lobes.


43. Kararizou E, Likomanos D, Gkiatas K, Markou I, Triantafyllou N, Kararizos G: Magnetic resonance spectroscopy: a noninvasive diagnosis of gliomatosis cerebri. Magn Reson Imaging; 2006 Feb;24(2):205-7
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  • [Title] Magnetic resonance spectroscopy: a noninvasive diagnosis of gliomatosis cerebri.
  • Gliomatosis cerebri (GC) is characterized by a diffuse infiltration of neoplastic glial cells with preservation of neuronal architecture.

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  • (PMID = 16455411.001).
  • [ISSN] 0730-725X
  • [Journal-full-title] Magnetic resonance imaging
  • [ISO-abbreviation] Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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44. Braeuninger S, Schneider-Stock R, Kirches E, Powers JM, Korones DN, Mawrin C: Evaluation of molecular genetic alterations associated with tumor progression in a case of gliomatosis cerebri. J Neurooncol; 2007 Mar;82(1):23-7
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  • [Title] Evaluation of molecular genetic alterations associated with tumor progression in a case of gliomatosis cerebri.
  • Gliomatosis cerebri (GC) is a rare tumor characterized by widespread infiltration of the brain and spinal cord.


45. Edo MC, Rovira A, Montalbán X: [Cerebral gliomatosis]. Neurologia; 2008 Mar;23(2):110-1

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  • [Title] [Cerebral gliomatosis].
  • [Transliterated title] Gliomatosis cerebri.
  • [MeSH-major] Cerebral Cortex / pathology. Neoplasms, Neuroepithelial / pathology

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  • (PMID = 18322829.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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46. Di Ieva A, Gaetani P, Giannini M, Aimar E, Levi D, Tancioni F, Secci L, Colombo P, Debernardi A, Scorsetti M, Navarria P, Rognone F, Rodriguez y Baena R: Oligodendroglial gliomatosis cerebri. Case report. J Neurosurg Sci; 2006 Dec;50(4):123-5
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  • [Title] Oligodendroglial gliomatosis cerebri. Case report.
  • Gliomatosis cerebri of oligodendroglial origin is very unusual.

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  • (PMID = 17285105.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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47. D'Urso PI, D'Urso OF, Marsigliante S, Storelli C, Distante A, Sanguedolce F, Cimmino A, Luzi G, Gianfreda CD, Montinaro A, Ciappetta P: Gliomatosis cerebri type II: two case reports. J Med Case Rep; 2009;3:7225

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  • [Title] Gliomatosis cerebri type II: two case reports.
  • INTRODUCTION: TWO TYPES OF GLIOMATOSIS CEREBRI EXIST: Type I and Type II.
  • We report the results of a histological and genetic study of two cases of gliomatosis cerebri Type II, correlating these results with therapy and prognosis.
  • CASE PRESENTATION: Two patients, a 52-year-old man (Patient 1) and a 76-year-old man (Patient 2) with gliomatosis cerebri II were admitted to our institution; they underwent surgical treatment and received radiotherapy and chemotherapy.

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  • [Cites] Ann Neurol. 2006 Dec;60(6):740-3 [17192931.001]
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  • (PMID = 19830138.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2726545
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48. Kumar V, Chakrabarti S, Modi M, Sahoo M: Late-onset obsessive compulsive disorder associated with possible gliomatosis cerebri. World J Biol Psychiatry; 2009;10(4 Pt 2):636-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Late-onset obsessive compulsive disorder associated with possible gliomatosis cerebri.
  • The current patient had obsessive images, anxiety, auditory hallucinations and seizures following (possible) gliomatosis cerebri, with onset around 69 years of age.
  • However, late-onset OCD has not been commonly reported with diffuse lesions, and the association with gliomatosis cerebri is not known.
  • [MeSH-minor] Aged. Anticonvulsants / therapeutic use. Aspartic Acid / analogs & derivatives. Aspartic Acid / metabolism. Choline / metabolism. Corpus Callosum / pathology. Dominance, Cerebral / physiology. Drug Therapy, Combination. Epilepsy, Tonic-Clonic / diagnosis. Epilepsy, Tonic-Clonic / drug therapy. Epilepsy, Tonic-Clonic / psychology. Hippocampus / pathology. Humans. Magnetic Resonance Imaging. Magnetic Resonance Spectroscopy. Male. Parietal Lobe / pathology. Temporal Lobe / pathology


49. Duron E, Lazareth A, Gaubert JY, Raso C, Hanon O, Rigaud AS: Gliomatosis cerebri presenting as rapidly progressive dementia and parkinsonism in an elderly woman: a case report. J Med Case Rep; 2008;2:53

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri presenting as rapidly progressive dementia and parkinsonism in an elderly woman: a case report.
  • We herein report a case of gliomatosis cerebri, a very rare brain tumor seldom affecting the elderly, which presented as rapidly progressive dementia and parkinsonism.
  • Cerebral magnetic resonance imaging (MRI) with gadolinium injection highlighted a diffuse tumor-related infiltration involving both lobes, the putamen, the pallidum, the substantia nigra, and the brainstem, corresponding to the specific description and definition of gliomatosis cerebri.
  • CONCLUSION: This atypical presentation of a gliomatosis cerebri, and the infiltration of the substantia nigra by the tumor, merits attention.

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  • (PMID = 18284707.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2263063
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50. Kuroki K, Sugiyama K, Taguchi H, Yukawa O, Kurokawa M, Kajiwara Y, Usui S, Kurisu K: [Gliomatosis cerebri. Report of two cases]. No Shinkei Geka; 2006 May;34(5):513-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Gliomatosis cerebri. Report of two cases].
  • Gliomatosis cerebri is a rare tumor of the central nervous system, and here we report two cases of this tumor.
  • The patient had no neurological deficits and no abnormal findings in clinical laboratory data, including data for the cerebral spinal fluid.
  • The patient was diagnosed with gliomatosis cerebri, and surgery and whole brain radiation at 44Gy were performed.
  • A specimen obtained by open biopsy revealed anaplastic oligodendroglioma, which was diagnosed as gliomatosis cerebri.
  • These cases suggest that radiation therapy is effective for gliomatosis cerebri.

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  • (PMID = 16689395.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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51. Bernsen H, Van der Laak J, Küsters B, Van der Ven A, Wesseling P: Gliomatosis cerebri: quantitative proof of vessel recruitment by cooptation instead of angiogenesis. J Neurosurg; 2005 Oct;103(4):702-6
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  • [Title] Gliomatosis cerebri: quantitative proof of vessel recruitment by cooptation instead of angiogenesis.
  • Gliomatosis cerebri is a rare glial tumor and represents an extreme example of such diffuse infiltrative growth.
  • The goal of this study was to establish the extent to which tumor angiogenesis occurs in gliomatosis cerebri.
  • METHODS: Computerized image analysis was performed to assess quantitatively two microvascular parameters (vessel density and diameter) in different areas of a brain harboring a gliomatosis cerebri.
  • These regions were the cerebral white and gray matter in which there was a diffuse infiltrative tumor, cerebral white and gray matter in which there was a more compact growth pattern of tumor cells, and normal cerebral white and gray matter.
  • The results of the quantitative analysis strongly indicated that in gliomatosis cerebri tumor, angiogenesis was completely absent, a finding that is corroborated by the fact that the microvasculature in gliomatosis cerebri persists in exhibiting immunohistochemical characteristics of the BBB.

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  • (PMID = 16266053.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Maramattom BV, Giannini C, Manno EM, Wijdicks EF, Campeau NG: Gliomatosis cerebri angiographically mimicking central nervous system angiitis: case report. Neurosurgery; 2006 Jun;58(6):E1209; discussion E1209
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  • [Title] Gliomatosis cerebri angiographically mimicking central nervous system angiitis: case report.
  • OBJECTIVE: The diagnosis of isolated central nervous system angiitis often requires both cerebral angiography and biopsy for diagnosis.
  • CLINICAL PRESENTATION: We present a case of gliomatosis cerebri with demonstrated angiographic changes suggestive of a central nervous system vasculitis.
  • A four-vessel angiogram revealed diffuse arterial beading with stenoses of a right frontal middle cerebral artery branch and the distal posterior cerebral artery and anterior cerebral artery branches, bilaterally.
  • The biopsy revealed a Grade 2 fibrillary astrocytoma consistent with gliomatosis cerebri.
  • CONCLUSION: Gliomatosis cerebri can mimic central nervous system vasculitis angiographically.
  • [MeSH-major] Angiography, Digital Subtraction. Cerebral Angiography. Cerebrovascular Disorders / diagnosis. Magnetic Resonance Imaging. Neoplasms, Neuroepithelial / diagnosis. Vasculitis / diagnosis

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  • (PMID = 16723870.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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53. Harrison JF, Richard HT, Abel TW, Sosnowski JS, Martino AM: Gliomatosis cerebri: report of 3 cases. J Neurosurg Pediatr; 2010 Sep;6(3):291-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri: report of 3 cases.
  • Gliomatosis cerebri is an uncommon glial neoplasm that is exceedingly rare in children and difficult to diagnose.
  • The authors emphasize the need to maintain gliomatosis cerebri in the differential diagnosis of children presenting with diffuse neurological signs and MR imaging evidence of widespread, infiltrative lesions.


54. Rorke-Adams LB, Portnoy H: Long-term survival of an infant with gliomatosis cerebelli. J Neurosurg Pediatr; 2008 Nov;2(5):346-50

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term survival of an infant with gliomatosis cerebelli.
  • Gliomatosis cerebri is an uncommon but well-established central nervous system neoplasm that occurs primarily in adults.

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  • (PMID = 18976105.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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55. Wachter-Giner T, Bieber I, Warmuth-Metz M, Bröcker EB, Hamm H: Multiple pilomatricomas and gliomatosis cerebri--a new association? Pediatr Dermatol; 2009 Jan-Feb;26(1):75-8
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  • [Title] Multiple pilomatricomas and gliomatosis cerebri--a new association?
  • A 15-year-old boy treated with temozolomide and oxcarbazepine for gliomatosis cerebri with symptomatic epilepsy developed four firm cutaneous nodules on his face and right upper arm in the course of 1 year.
  • This is the first published case of a patient suffering from gliomatosis cerebri and developing multiple pilomatricomas.

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  • (PMID = 19250412.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. Inamasu J, Nakatsukasa M, Kuramae T, Masuda Y, Tomiyasu K, Yamada T: Gliomatosis cerebri mimicking chemotherapy-induced leukoencephalopathy in a patient with non-Hodgkin's lymphoma. Intern Med; 2010;49(7):701-5
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  • [Title] Gliomatosis cerebri mimicking chemotherapy-induced leukoencephalopathy in a patient with non-Hodgkin's lymphoma.
  • The lesions, initially diagnosed with toxic leukoencephalopathy based on MRI findings, turned out to be gliomatosis cerebri.

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  • (PMID = 20371962.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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57. Asada T, Takayama Y, Tokuriki Y, Fukuyama H: Gliomatosis cerebri presenting as a parkinsonian syndrome. J Neuroimaging; 2007 Jul;17(3):269-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri presenting as a parkinsonian syndrome.
  • At the latest admission, extensive diffuse white matter high-intensity areas were present on T2-weighted magnetic resonance imaging images, and stereotactic brain biopsy showed that these lesions were gliomatosis cerebri (GC).

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  • (PMID = 17608917.001).
  • [ISSN] 1051-2284
  • [Journal-full-title] Journal of neuroimaging : official journal of the American Society of Neuroimaging
  • [ISO-abbreviation] J Neuroimaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Desclée P, Rommel D, Hernalsteen D, Godfraind C, de Coene B, Cosnard G: Gliomatosis cerebri, imaging findings of 12 cases. J Neuroradiol; 2010 Jul;37(3):148-58
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri, imaging findings of 12 cases.
  • BACKGROUND AND PURPOSE: We report 12 cases of Gliomatosis cerebri (GC), a rare brain neoplasm, to define its semeiologic criteria.


59. Galanaud D, Nicoli F, Confort-Gouny S, Le Fur Y, Ranjeva JP, Viola A, Girard N, Cozzone PJ: [Indications for cerebral MR proton spectroscopy in 2007]. Rev Neurol (Paris); 2007 Mar;163(3):287-303
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  • [Title] [Indications for cerebral MR proton spectroscopy in 2007].
  • [Transliterated title] Spectroscopie par résonance magnétique du proton. Quelles indications neurologiques en 2007?
  • The most important applications in clinical practice are intracranial space occupying lesions (especially the positive diagnosis of intracranial abscesses and gliomatosis cerebri and the differential diagnosis between edema and tumor infiltration), alcoholic, hepatic, and HIV-related encephalopathies and the exploration of metabolic diseases.

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  • (PMID = 17404517.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 145
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60. Stark AM, Maslehaty H, Hugo HH, Mahvash M, Mehdorn HM: Glioblastoma of the cerebellum and brainstem. J Clin Neurosci; 2010 Oct;17(10):1248-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients younger than 21years of age, as well as patients with gliomatosis cerebri, were excluded from the analysis.

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  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20619657.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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61. Leeds NE, Lang FF, Ribalta T, Sawaya R, Fuller GN: Origin of chordoid glioma of the third ventricle. Arch Pathol Lab Med; 2006 Apr;130(4):460-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: Chordoid glioma is a relatively recently described unique glial neoplasm that has been formally codified by the World Health Organization in Pathology and Genetics of Tumours of the Nervous System, in which it is included along with astroblastoma and gliomatosis cerebri under the rubric "Tumors of Uncertain Origin."

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  • [CommentIn] Arch Pathol Lab Med. 2006 Apr;130(4):437-8 [16594734.001]
  • (PMID = 16594739.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / Vimentin
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62. Kong DS, Kim MH, Park WY, Suh YL, Lee JI, Park K, Kim JH, Nam DH: The progression of gliomas is associated with cancer stem cell phenotype. Oncol Rep; 2008 Mar;19(3):639-43
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  • Using 12 surgical specimens of gliomatosis cerebri (GC) in the early and advanced stages, we measured the expression of a panel of cell proliferation, microvessel density, microvessel areas, angiogenic factors and their associated receptors.

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  • (PMID = 18288395.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers
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63. Maurer E, Botteron C, Ehrensperger F, Fatzer R, Jaggy A, Kolly C, Meylan M, Zurbriggen A, Doherr MG: [Swiss scrapie surveillance. I. Clinical aspects of neurological diseases in sheep and goats]. Schweiz Arch Tierheilkd; 2005 Oct;147(10):425-33
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  • Among the 22 neurological field cases examined in this study, a goat with cerebral gliomatosis and hair lice showed the closest similarity to clinical scrapie.
  • The unilateral deficiency of the cerebral nerves has potential as an clinical exclusion criterion for scrapie.

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  • (PMID = 16259408.001).
  • [ISSN] 0036-7281
  • [Journal-full-title] Schweizer Archiv für Tierheilkunde
  • [ISO-abbreviation] Schweiz. Arch. Tierheilkd.
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
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64. Horger M, Fenchel M, Nägele T, Moehle R, Claussen CD, Beschorner R, Ernemann U: Water diffusivity: comparison of primary CNS lymphoma and astrocytic tumor infiltrating the corpus callosum. AJR Am J Roentgenol; 2009 Nov;193(5):1384-7
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  • MATERIALS AND METHODS: Echo-planar diffusion-weighted MR images of 27 patients with glioblastoma multiforme, five patients with low-grade astrocytoma, five patients with gliomatosis cerebri, and nine patients with primary lymphoma infiltrating the corpus callosum were reviewed retrospectively.
  • RESULTS: The mean ADC of glioblastoma multiforme was 1.13 +/- 0.31 (SD) x 10(-3) mm(2)/s, and the mean tumor to corpus callosum ADC ratio was 1.51 +/- 0.46; of low-grade astrocytoma, 1.14 +/- 0.23 x 10(-3) mm(2)/s and 1.54 +/- 0.28; gliomatosis cerebri, 1.01 +/- 0.20 x 10(-3) mm(2)/s and 1.31 +/- 0.36; and lymphoma, 0.71 +/- 0.13 x 10(-3) mm(2)/s and 0.93 +/- 0.19.

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  • (PMID = 19843757.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 059QF0KO0R / Water
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65. Soffietti R, Leoncini B, Rudà R: New developments in the treatment of malignant gliomas. Expert Rev Neurother; 2007 Oct;7(10):1313-26
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  • Gliomatosis cerebri is a rare diffuse glioma, and upfront chemotherapy is increasingly being employed instead of whole-brain radiotherapy to avoid/delay cognitive defects in long surviving patients, despite the lack of data to support this.

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  • (PMID = 17939769.001).
  • [ISSN] 1744-8360
  • [Journal-full-title] Expert review of neurotherapeutics
  • [ISO-abbreviation] Expert Rev Neurother
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Drugs, Investigational
  • [Number-of-references] 144
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66. Jeannin S, Lebrun C, Van Den Bos F, Olschwang S, Bourg V, Frenay M: [Turcot's syndrome confirmed by molecular biological tests]. Rev Neurol (Paris); 2006 Jun;162(6-7):741-6
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  • Eight years after the diagnosis, the patient developed a gliomatosis cerebri and died.

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  • (PMID = 16840983.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Carrier Proteins; 0 / MLH1 protein, human; 0 / Nuclear Proteins; EC 3.6.1.3 / MSH2 protein, human; EC 3.6.1.3 / MutS Homolog 2 Protein
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67. Heimberger AB, Suki D, Yang D, Shi W, Aldape K: The natural history of EGFR and EGFRvIII in glioblastoma patients. J Transl Med; 2005 Oct 19;3:38
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  • There was no significant difference in multifocal disease or gliomatosis cerebri among EGFR expression groups.

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  • (PMID = 16236164.001).
  • [ISSN] 1479-5876
  • [Journal-full-title] Journal of translational medicine
  • [ISO-abbreviation] J Transl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1298339
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68. Deramecourt V, Bombois S, Debette S, Delbeuck X, Ramirez C, Reyns N, Kerdraon O, Maurage CA, Pasquier F: Bilateral temporal glioma presenting as a paraneoplastic limbic encephalitis with pure cognitive impairment. Neurologist; 2009 Jul;15(4):208-11
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  • The left temporal tumor was resected and the neuropathological examination was consistent with gliomatosis cerebri with a focal high grade astrocytoma.
  • CONCLUSIONS: This case highlights the need to consider the possibility of infiltrative gliomatosis in patients presenting with features of paraneoplastic limbic encephalitis.

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  • (PMID = 19590380.001).
  • [ISSN] 2331-2637
  • [Journal-full-title] The neurologist
  • [ISO-abbreviation] Neurologist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies
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69. Singh A, Kesavadas C, Radhakrishnan M, Santhosh K, Nair M, Menon G, Radhakrishnan VV: Primary diffuse leptomeningeal gliomatosis. J Neuroradiol; 2009 Mar;36(1):52-6
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  • [Title] Primary diffuse leptomeningeal gliomatosis.
  • Histopathological examination was suggestive of a low-grade glioma, and the patient was diagnosed with primary diffuse leptomeningeal gliomatosis.

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  • (PMID = 18707759.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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70. Marsaudon X, Fermeaux V, Mathonnet M: [Peritoneal pseudo-carcinosis in a young woman: peritoneal gliomatosis]. Gastroenterol Clin Biol; 2005 Jun-Jul;29(6-7):740-2
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  • [Title] [Peritoneal pseudo-carcinosis in a young woman: peritoneal gliomatosis].
  • [Transliterated title] Une pseudo-carcinose péritonéale de la jeune femme: la gliomatose péritonéale.
  • Gliomatosis peritonei is a peritoneal colonization of glial cells producing nodules similar to peritoneum carcinosis.
  • Gliomatosis is often associated with ovarian teratoma.
  • We describe a case of gliomatosis 8 years after the removal of a mature ovarian teratoma.

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  • (PMID = 16142011.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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71. Jicha GA, Glantz J, Clarke MJ, Lehwald LM, Russo DP, Giannini C, Wald JT, Uhm J, Kumar N, Aksamit AJ, Wetmore CJ: Primary diffuse leptomeningeal gliomatosis. Eur Neurol; 2009;62(1):16-22
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  • [Title] Primary diffuse leptomeningeal gliomatosis.
  • BACKGROUND: Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare presentation of a primary central nervous system glial tumor.

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  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19407451.001).
  • [ISSN] 1421-9913
  • [Journal-full-title] European neurology
  • [ISO-abbreviation] Eur. Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide
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72. Choi JW, Lee MM, Kim IA, Kim JH, Choe G, Kim CY: The outcomes of concomitant chemoradiotherapy followed by adjuvant chemotherapy with temozolomide for newly diagnosed high grade gliomas : the preliminary results of single center prospective study. J Korean Neurosurg Soc; 2008 Oct;44(4):222-7

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  • OBJECTIVE: Malignant gliomas are the most common primary cerebral neoplasms in adults.
  • Pathologically, glioblastoma, anaplastic astrocytoma, anaplastic oligodendroglioma, and gliomatosis cerebri had been diagnosed in eighteen, eight, four, and two patients, respectively.

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  • (PMID = 19096681.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588321
  • [Keywords] NOTNLM ; Concomitant chemoradiotherapy / Glioblastoma / High-grade glioma / Temozolomide
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73. Noun M, Ennachit M, Boufettal H, Elmouatacim K, Samouh N: [The ovarian immature teratoma with gliomatosis peritonei]. J Gynecol Obstet Biol Reprod (Paris); 2007 Oct;36(6):595-601
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  • [Title] [The ovarian immature teratoma with gliomatosis peritonei].
  • [Transliterated title] Tératome immature de l'ovaire avec gliomatose péritonéale. A propos d'un cas et revue de la littérature.
  • OBJECTIVE: We return a case of ovarian immature teratoma with peritoneal gliomatose at a woman aged of 20 years.
  • Gliomatosis peritonei is a rare situation, characterized by the recurrence of peritoneal implants after the surgical treatment of ovarian teratoma.

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  • (PMID = 17537589.001).
  • [ISSN] 0368-2315
  • [Journal-full-title] Journal de gynécologie, obstétrique et biologie de la reproduction
  • [ISO-abbreviation] J Gynecol Obstet Biol Reprod (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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74. Richard HT, Harrison JF, Abel TW, Maertens P, Martino AM, Sosnowski JS: Pediatric gliomatosis cerebri mimicking acute disseminated encephalomyelitis. Pediatrics; 2010 Aug;126(2):e479-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric gliomatosis cerebri mimicking acute disseminated encephalomyelitis.
  • Gliomatosis cerebri (GC) is a diffuse infiltrating glial neoplasm of astrocytic origin.


75. Pichler R, Dunzinger A, Wurm G, Pichler J, Weis S, Nussbaumer K, Topakian R, Aigner RM: Is there a place for FET PET in the initial evaluation of brain lesions with unknown significance? Eur J Nucl Med Mol Imaging; 2010 Aug;37(8):1521-8
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  • Remarkably, the two patients with cerebral gliomatosis were false-negative on FET PET imaging.

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  • (PMID = 20396883.001).
  • [ISSN] 1619-7089
  • [Journal-full-title] European journal of nuclear medicine and molecular imaging
  • [ISO-abbreviation] Eur. J. Nucl. Med. Mol. Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / O-(2-fluoroethyl)tyrosine; 0Z5B2CJX4D / Fluorodeoxyglucose F18; 42HK56048U / Tyrosine
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76. Ide T, Uchida K, Kikuta F, Suzuki K, Nakayama H: Immunohistochemical characterization of canine neuroepithelial tumors. Vet Pathol; 2010 Jul;47(4):741-50
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  • Gliomatosis cerebri (n = 3) consisted of cells positive for ionized calcium-binding adaptor molecule 1 and GFAP, including a minor population of cells positive for nestin, DCX, and beta III tubulin, suggesting their glial differentiation.
  • As for antiapoptotic cell death molecules, most tumor cells in the choroid plexus tumors, PNETs, and neuroblastomas were intensely positive for Bcl-2 and Bcl-xL, whereas those in gliomatosis cerebri were almost negative.


77. Broniscer A, Chintagumpala M, Fouladi M, Krasin MJ, Kocak M, Bowers DC, Iacono LC, Merchant TE, Stewart CF, Houghton PJ, Kun LE, Ledet D, Gajjar A: Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children. J Neurooncol; 2006 Feb;76(3):313-9
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  • We conducted a multi-institutional study to evaluate the efficacy of temozolomide given after radiotherapy in children with newly diagnosed high-grade glioma and unfavorable low-grade glioma (gliomatosis cerebri or bithalamic involvement).
  • Tumors most commonly involved cerebral hemispheres (n = 13, 42%) and thalamus (n = 14, 45%).

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  • (PMID = 16200343.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA21765
  • [Publication-type] Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Antineoplastic Agents, Phytogenic; 7673326042 / irinotecan; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide; XT3Z54Z28A / Camptothecin
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78. Shelekhova KV: [Peritoneal gliomatosis in immature ovarian teratoma]. Arkh Patol; 2008 Sep-Oct;70(5):34-5
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  • [Title] [Peritoneal gliomatosis in immature ovarian teratoma].
  • The paper describes another case of peritoneal gliomatosis associated with immature ovarian teratoma in an 11-year-old girl.

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  • (PMID = 19137782.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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79. Targnion A, Broze B, Habonimana E, Jouan H, Frémond B: [Gliomatosis peritonei, an unusual abdominal carcinomatosis: report of two cases]. Arch Pediatr; 2010 Aug;17(8):1169-73
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  • [Title] [Gliomatosis peritonei, an unusual abdominal carcinomatosis: report of two cases].
  • [Transliterated title] La gliomatose péritonéale: un aspect inhabituel de carcinomatose: à propos de deux cas.
  • We report on 2 cases of ovarian teratoma associated with gliomatosis peritonei in 2 young girls aged 9 and 14 years.
  • Gliomatosis peritonei is an unusual miliary-like peritoneal carcinomatosis of glial tissue.

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  • [Copyright] Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20452193.001).
  • [ISSN] 1769-664X
  • [Journal-full-title] Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
  • [ISO-abbreviation] Arch Pediatr
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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80. Pereira LS, McCulley TJ: Perineural arachnoidal gliomatosis: case report. Arq Bras Oftalmol; 2008 Jul-Aug;71(4):595-8

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  • [Title] Perineural arachnoidal gliomatosis: case report.
  • Gliomas are the most common infiltrative neoplasms of the optic nerve and can present as two distinct growth patterns: intraneural glial proliferation and perineural arachnoidal gliomatosis (PAG).
  • It has been suggested that perineural arachnoidal gliomatosis is seen almost exclusively in the setting of neurofibromatosis type 1 (NF1).
  • We describe a child with perineural arachnoidal gliomatosis occurring without neurofibromatosis type 1, supported by both radiographic and histological findings.
  • Magnetic resonance imaging (MRI) revealed an enhancing fusiform intraconal lesion, which was hypointense on T1 and hyperintense on T2-weighted images: characteristic of perineural arachnoidal gliomatosis, the optic nerve was visualized coursing the tumor.
  • Histopathologic study was consistent with perineural arachnoidal gliomatosis.
  • Perineural arachnoidal gliomatosis can develop independent of neurofibromatosis type 1, as demonstrated by this case.

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  • (PMID = 18797677.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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81. Shooman D, Belli A, Grundy PL: Image-guided frameless stereotactic biopsy without intraoperative neuropathological examination. J Neurosurg; 2010 Aug;113(2):170-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Two patients suffered delayed deterioration and died due to probable surgical complications--one with thalamic glioblastoma multiforme (GBM) and one with gliomatosis cerebri.

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  • [CommentIn] J Neurosurg. 2010 Aug;113(2):167-8; discussion 168-9 [20136395.001]
  • (PMID = 20136389.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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82. Debono B, Derrey S, Rabehenoina C, Proust F, Freger P, Laquerrière A: Primary diffuse multinodular leptomeningeal gliomatosis: case report and review of the literature. Surg Neurol; 2006 Mar;65(3):273-82; discussion 282

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary diffuse multinodular leptomeningeal gliomatosis: case report and review of the literature.
  • BACKGROUND: Primary diffuse leptomeningeal gliomatosis is an exceptional neoplasm, and only 30 cases have been reported in the literature.
  • RESULTS: Complete neuraxis postmortem examination revealed no intraparenchymatous glioma and was conclusive for the diagnosis of primary leptomeningeal gliomatosis (astrocytic, World Health Organization grade III), with a multinodular pattern in the spinal cord, the brainstem, and the brain base with diffuse extension into the cerebellar subarachnoid spaces.
  • In most cases, autopsy evaluation alone permits definitive primary diffuse leptomeningeal gliomatosis diagnosis.

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  • (PMID = 16488248.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 39
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83. Yeo DM, Lim GY, Lee YS, Sohn DW, Chung JH: Gliomatosis peritonei of the scrotal sac associated with an immature gastric teratoma. Pediatr Radiol; 2010 Jul;40(7):1288-92
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  • [Title] Gliomatosis peritonei of the scrotal sac associated with an immature gastric teratoma.
  • After surgical excision, histology showed gliomatosis peritonei.
  • We report an unusual presentation of gliomatosis peritonei arising from a rare lesion of immature gastric teratoma.

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  • (PMID = 20135112.001).
  • [ISSN] 1432-1998
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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84. Okamoto D, Ishigami K, Yoshimitsu K, Irie H, Tajima T, Asayama Y, Hirakawa M, Ushijima Y, Nishihara Y, Amada S, Kobayashi H, Honda H: Gliomatosis peritonei associated with immature ovarian teratoma: a mimicker of peritoneal dissemination of malignant diseases. J Comput Assist Tomogr; 2007 Mar-Apr;31(2):317-9
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  • [Title] Gliomatosis peritonei associated with immature ovarian teratoma: a mimicker of peritoneal dissemination of malignant diseases.
  • A rare case of gliomatosis peritonei associated with immature ovarian teratoma was reported.
  • The computed tomographic findings of gliomatosis peritonei were similar to the classic findings of peritoneal dissemination of malignant tumors.

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  • (PMID = 17414772.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Contrast Media
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85. de Toledo M, López-Valdés E, Ferreiro M, Cervera JL, Ramos A, Cabello A, Hernández-Laín A, Montes-Montes S, Lagares A, Alvarez-Linera Prado J: [Lymphomatosis cerebri as the cause of leukoencephalopathy]. Rev Neurol; 2008 Jun 1-15;46(11):667-70
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  • [Title] [Lymphomatosis cerebri as the cause of leukoencephalopathy].
  • [Transliterated title] Linfomatosis cerebral como causa de leucoencefalopatía.
  • INTRODUCTION: Lymphomatosis cerebri (LC) is an infrequent type of primary lymphoma of the central nervous system that is characterised by diffuse, infiltrating involvement of the white matter of the brain without the formation of a mass.
  • CONCLUSIONS: The imaging and histological appearance of LC may not be the one typically found in primary lymphomas of the central nervous system, and its clinical presentation may be similar to that of other diffuse processes involving compromise of the white matter (cerebral gliomatosis, inflammatory diseases of the white matter, such as Behçet's disease, Sjögren's disease or systemic lupus erythematosus).

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  • (PMID = 18509825.001).
  • [ISSN] 1576-6578
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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86. Taillibert S, Chodkiewicz C, Laigle-Donadey F, Napolitano M, Cartalat-Carel S, Sanson M: Gliomatosis cerebri: a review of 296 cases from the ANOCEF database and the literature. J Neurooncol; 2006 Jan;76(2):201-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri: a review of 296 cases from the ANOCEF database and the literature.
  • Gliomatosis cerebri (GC) is a rare disease, defined as a diffuse neoplastic glial cell infiltration of the brain.
  • It was higher for patients younger than 42 years (17 months vs. 13 months), with performance status>or=80 (27 months vs. 9 months), low grade gliomatosis (grade 2=20 months, grade 3=11.5 months, grade 4=8.5 months), oligodendroglial subtype (36 months compared to 14 months for mixed GC and 11 months for astrocytic GC).

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  • (PMID = 16200347.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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87. England RA, deSouza NM, Kaye SB: Gliomatosis peritonei: MRI appearances and its potential role in follow up. Br J Radiol; 2007 May;80(953):e101-4
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  • [Title] Gliomatosis peritonei: MRI appearances and its potential role in follow up.
  • Gliomatosis peritonei is a rare complication of ovarian teratomas characterized by peritoneal implants of glial tissue.
  • We present a case of immature ovarian teratoma complicated by the development of low grade gliomatosis peritonei.

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  • (PMID = 17638834.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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88. Ghostine S, Raghavan R, Michelson D, Holshouser B, Tong K: Gliomatosis cerebri mimicking Rasmussen encephalitis. Case report. J Neurosurg; 2007 Aug;107(2 Suppl):143-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri mimicking Rasmussen encephalitis. Case report.
  • Gliomatosis cerebri (GC) is a distinct malignant neuroepithelial neoplasm that is rarely found in children.


89. Das CJ, Sharma R, Thulkar S, Mukhopadhyay S, Deka D, Mannan R: Mature ovarian teratoma with gliomatosis peritonei--a case report. Indian J Cancer; 2005 Jul-Sep;42(3):165-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mature ovarian teratoma with gliomatosis peritonei--a case report.
  • Gliomatosis peritonei (GP), a rare condition related to ovarian teratomas, is characterized by miliary implants of mature glial tissues on the peritoneum or omentum.

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  • (PMID = 16276020.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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90. Ko MW, Turkeltaub PE, Lee EB, Gonatas NK, Volpe NJ, Moster ML, Galetta SL: Primary diffuse leptomeningeal gliomatosis mimicking a chronic inflammatory meningitis. J Neurol Sci; 2009 Mar 15;278(1-2):127-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary diffuse leptomeningeal gliomatosis mimicking a chronic inflammatory meningitis.
  • Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare, fatal, neoplastic condition of infiltrating glial cells into the meninges without evidence of primary tumor in the brain or spinal cord parenchyma.
  • Primary diffuse leptomeningeal gliomatosis often presents with symptoms and physical findings of chronic inflammatory meningitis and raised intracranial pressure, and lacks specific clinical, radiologic, and diagnostic criteria.

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  • (PMID = 19135216.001).
  • [ISSN] 0022-510X
  • [Journal-full-title] Journal of the neurological sciences
  • [ISO-abbreviation] J. Neurol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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91. Armstrong GT, Phillips PC, Rorke-Adams LB, Judkins AR, Localio AR, Fisher MJ: Gliomatosis cerebri: 20 years of experience at the Children's Hospital of Philadelphia. Cancer; 2006 Oct 1;107(7):1597-606
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gliomatosis cerebri: 20 years of experience at the Children's Hospital of Philadelphia.
  • BACKGROUND: Gliomatosis cerebri (GC) is a rare and typically fatal glial neoplasm of the central nervous system.

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  • [Copyright] (c) 2006 American Cancer Society.
  • (PMID = 16955507.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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92. Khan J, McClennan BL, Qureshi S, Martell M, Iyer A, Bokhari SJ: Meigs syndrome and gliomatosis peritonei: a case report and review of literature. Gynecol Oncol; 2005 Aug;98(2):313-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meigs syndrome and gliomatosis peritonei: a case report and review of literature.
  • To the best of our knowledge, pseudo-Meigs syndrome (PMS) has never been described in the setting of gliomatosis peritonei (GP), both arising from an ovarian teratoma.
  • The case is also rare because lymph node involvement along with gliomatosis was found.

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  • (PMID = 15963555.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 42
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93. Lipskar AM, Rothstein DH, Soffer SZ, Edelman M, Glick RD: Intrathoracic glial implants in a child with gliomatosis peritonei. J Pediatr Surg; 2009 Sep;44(9):1817-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intrathoracic glial implants in a child with gliomatosis peritonei.
  • Glial peritoneal implants, commonly referred to as gliomatosis peritonei, are an occasional feature of ovarian teratomas.
  • Pleural gliomatosis has not been described in the literature.
  • The pathophysiology of gliomatosis peritonei was originally thought to be the direct extrusion or lymphatic spread of glial cells from the associated teratoma, although it has been postulated that the glial implants may instead be the result of pluripotent Mullerian stem cells that undergo metaplasia.

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  • (PMID = 19735831.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Torikai M, Tahara H, Kaji T, Shimono R, Yano T, Yoshioka T, Kawakami K, Takamatsu H: Immature teratoma of gallbladder associated with gliomatosis peritonei, a case report. J Pediatr Surg; 2007 Oct;42(10):E25-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immature teratoma of gallbladder associated with gliomatosis peritonei, a case report.
  • At the operation, a tumor arising from gallbladder and gliomatosis peritonei with intact ovaries were found.
  • This is a rare case report of teratoma that originated in the gallbladder associated with gliomatosis peritonei.

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  • (PMID = 17923185.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; VAC protocol
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95. Franceschi E, Cavallo G, Scopece L, Esposti RD, Paioli G, Paioli A, Palmerini E, Foschini MP, Marliani AF, Crinò L: Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis. J Neurooncol; 2005 Jul;73(3):261-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis.
  • Herein we describe the case of a patient with primary diffuse leptomeningeal gliomatosis (PDLG).

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  • (PMID = 15980977.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide
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96. Kim SH, Jun DC, Park JS, Heo JH, Kim SM, Kim J, Paek SH, Kim M: Primary diffuse leptomeningeal gliomatosis: report of a case presenting with chronic meningitis. J Clin Neurol; 2006 Sep;2(3):202-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary diffuse leptomeningeal gliomatosis: report of a case presenting with chronic meningitis.
  • Primary diffuse leptomeningeal gliomatosis is a rare condition whereby a glioma arises from heterotopic cell nests in the leptomeninges.
  • Leptomeningeal biopsy sampling revealed the condition to be primary diffuse leptomeningeal gliomatosis.

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  • [Cites] Surg Neurol. 2006 Mar;65(3):273-82; discussion 282 [16488248.001]
  • [Cites] Neurol Sci. 2005 Jun;26(2):129-34 [15995830.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2000 Sep;69(3):385-8 [10945815.001]
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  • (PMID = 20396508.001).
  • [ISSN] 2005-5013
  • [Journal-full-title] Journal of clinical neurology (Seoul, Korea)
  • [ISO-abbreviation] J Clin Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2854966
  • [Keywords] NOTNLM ; Chronic meningitis / Primary diffuse leptomeningeal gliomatosis
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97. Bhatia R, Roncaroli F, Thomas P, Cheah SL, Mehta A, Glaser M, Ulbricht C: A case of primary leptomeningeal gliomatosis confined to the spinal cord. J Neurooncol; 2010 May;98(1):125-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of primary leptomeningeal gliomatosis confined to the spinal cord.
  • We report a case of primary leptomeningeal gliomatosis limited to the spinal cord occurring in a 52 years-old patient, who presented with back pain and leg weakness.
  • Primary leptomeningeal gliomatosis exclusively involving the spinal cord is an extremely rare condition bearing a dismal prognosis.

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  • (PMID = 19898776.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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98. Hsieh YL, Liu CS: Progression from an immature teratoma with miliary gliomatosis peritonei to growing teratoma syndrome with nodular gliomatosis peritonei. Pediatr Neonatol; 2009 Apr;50(2):78-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Progression from an immature teratoma with miliary gliomatosis peritonei to growing teratoma syndrome with nodular gliomatosis peritonei.
  • A 4 1/2-year-old girl presented with an incompletely resected, huge, immature abdominal teratoma, elevated serum alpha-fetoprotein (AFP), and numerous miuiary gliomatosis peritonei (GP).

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  • (PMID = 19453084.001).
  • [ISSN] 1875-9572
  • [Journal-full-title] Pediatrics and neonatology
  • [ISO-abbreviation] Pediatr Neonatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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99. Karlo C, Leschka S, Dettmer M, Breitenstein S, Stolzmann P: Hepatic teratoma and peritoneal gliomatosis: a case report. Cases J; 2009;2:9302

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic teratoma and peritoneal gliomatosis: a case report.
  • In our case the hepatic teratoma is associated with peritoneal gliomatosis, which is an indicator for an ongoing peritoneal spread of a teratoma.

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  • [Cites] Hum Pathol. 2004 Jun;35(6):685-8 [15188134.001]
  • [Cites] Acta Gastroenterol Belg. 2008 Apr-Jun;71(2):275-9 [18720943.001]
  • [Cites] Gynecol Oncol. 2004 Dec;95(3):746-9 [15581997.001]
  • [Cites] Int J Oncol. 2004 Jul;25(1):17-25 [15201985.001]
  • (PMID = 20062626.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2803966
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100. Ishige S, Iwadate Y, Ishikura H, Saeki N: Primary diffuse leptomeningeal gliomatosis followed with serial magnetic resonance images. Neuropathology; 2007 Jun;27(3):290-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary diffuse leptomeningeal gliomatosis followed with serial magnetic resonance images.
  • We report a case of primary diffuse leptomeningeal gliomatosis (PDLG) followed up with serial magnetic resonance images (MRI).
  • Repeated MRI revealed diffuse leptomeningeal enhancement throughout the central nervous system without intra-axial mass accompanied with the dilatation of ventricles and focally enlarged cerebral sulci.
  • Brain biopsies showed a leptomeningeal gliomatosis.

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  • (PMID = 17645245.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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