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1. Vaquero E, Gómez CM, Quintero EA, González-Rosa JJ, Márquez J: Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor. Behav Brain Funct; 2008;4:18
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  • [Title] Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor.
  • BACKGROUND: This study was realized thanks to the collaboration of children and adolescents who had been resected from cerebellar tumors.
  • The astrocytoma group (CE, n = 13) did not receive additional treatments.
  • The Astrocytoma group also showed executive deficits in digits span, semantic fluency (animal category) and moderate to slight deficit in Stroop (word and colour) tests.
  • In the astrocytoma group, the tumor's localization and dentate affectation showed different profile and level of impairment: moderate to slight for vermal and hemispheric patients respectively.
  • CONCLUSION: Results suggest a differential prefrontal-like deficit due to cerebellar lesions and/or cerebellar-frontal diaschisis, as indicate the results in astrocytoma group (without treatments), that also can be generated and/or increased by treatments in the medulloblastoma group.
  • The results are also discussed in the context of the Cerebellar Cognitive Affective Syndrome.

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  • (PMID = 18412947.001).
  • [ISSN] 1744-9081
  • [Journal-full-title] Behavioral and brain functions : BBF
  • [ISO-abbreviation] Behav Brain Funct
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2362115
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2. Linscott LL, Osborn AG, Blaser S, Castillo M, Hewlett RH, Wieselthaler N, Chin SS, Krakenes J, Hedlund GL, Sutton CL: Pilomyxoid astrocytoma: expanding the imaging spectrum. AJNR Am J Neuroradiol; 2008 Nov;29(10):1861-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pilomyxoid astrocytoma: expanding the imaging spectrum.
  • BACKGROUND AND PURPOSE: Pilomyxoid astrocytoma (PMA) is a recently described variant of pilocytic astrocytoma (PA) with unique clinical and histopathologic characteristics.
  • Nine (43%) occurred in other locations, including the parietal lobe (2/21), temporal lobe (2/21), cerebellum (2/21), basal ganglia (2/21), and fourth ventricle (1/21).
  • [MeSH-major] Astrocytoma / classification. Astrocytoma / diagnosis. Brain Neoplasms / classification. Brain Neoplasms / diagnosis. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 18701580.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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3. Otero-Rodríguez A, Sarabia-Herrero R, García-Tejeiro M, Zamora-Martínez T: Spontaneous malignant transformation of a supratentorial pilocytic astrocytoma. Neurocirugia (Astur); 2010 Jun;21(3):245-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous malignant transformation of a supratentorial pilocytic astrocytoma.
  • Pilocytic astrocytoma (PA) is a circumscribed neoplasia considered as a grade I astrocytoma by the World Health Organization.
  • Its most common location is the cerebellum and it develops during the first two decades of the life.
  • [MeSH-major] Astrocytoma / pathology. Cell Transformation, Neoplastic / pathology. Supratentorial Neoplasms / pathology

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  • (PMID = 20571729.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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4. Stüer C, Vilz B, Majores M, Becker A, Schramm J, Simon M: Frequent recurrence and progression in pilocytic astrocytoma in adults. Cancer; 2007 Dec 15;110(12):2799-808
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  • [Title] Frequent recurrence and progression in pilocytic astrocytoma in adults.
  • BACKGROUND: Most pilocytic astrocytomas (piloA) are benign growths (World Health Organization [WHO] grade 1) of the deep midline structures, the brainstem, and the cerebellum.
  • RESULTS: There were 20 patients (45%) with supratentorial lobar piloA (including 10 temporal/temporomesial tumors, 5 parietal tumors, 3 insular tumors, 1 frontal tumor, and 1 occipital tumors), 12 patients with cerebellar piloA, 7 patients with brainstem piloA, 2 patients with opticochiasmatic PiloA, 1 patient with intramedullary piloA, and 2 patients with piloA of the basal ganglia.
  • [MeSH-major] Astrocytoma / pathology. Astrocytoma / radiography. Brain Neoplasms / pathology

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  • [CommentIn] Nat Clin Pract Neurol. 2008 Jun;4(6):296-7 [18414467.001]
  • (PMID = 17973253.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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5. Marinovic T, Grahovac G, Habek M, Lambasa S, Tomac D: Simultaneous conus medullaris ependymoma and cerebellar astrocytoma in the same patient. Clin Neuropathol; 2009 May-Jun;28(3):173-6
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  • [Title] Simultaneous conus medullaris ependymoma and cerebellar astrocytoma in the same patient.
  • We report a patient who had pilocytic astrocytoma in the cerebellum and ependymoma in the cauda equina region, occurring simultaneously.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Ependymoma / pathology. Neoplasms, Multiple Primary / pathology. Spinal Cord Neoplasms / pathology

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  • (PMID = 19537133.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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6. Zeng N, Liu L, McCabe MG, Jones DT, Ichimura K, Collins VP: Real-time quantitative polymerase chain reaction (qPCR) analysis with fluorescence resonance energy transfer (FRET) probes reveals differential expression of the four ERBB4 juxtamembrane region variants between medulloblastoma and pilocytic astrocytoma. Neuropathol Appl Neurobiol; 2009 Aug;35(4):353-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Real-time quantitative polymerase chain reaction (qPCR) analysis with fluorescence resonance energy transfer (FRET) probes reveals differential expression of the four ERBB4 juxtamembrane region variants between medulloblastoma and pilocytic astrocytoma.
  • AIMS: We report a comparative study on the mRNA expression of ErbB receptor tyrosine kinases, and in particular ERBB4 transcript variants, in two common paediatric brain tumours: medulloblastoma (MB) and pilocytic astrocytoma (PA).
  • [MeSH-major] Astrocytoma / metabolism. Brain / metabolism. Brain Neoplasms / metabolism. Medulloblastoma / metabolism. Receptor, Epidermal Growth Factor / metabolism
  • [MeSH-minor] Cerebellum / metabolism. Fluorescence Resonance Energy Transfer. Gene Expression. Genetic Variation. Humans. Peptide Hydrolases / metabolism. Polymerase Chain Reaction. RNA, Messenger / metabolism. Receptor, ErbB-2 / genetics. Receptor, ErbB-2 / metabolism. Receptor, ErbB-3 / genetics. Receptor, ErbB-3 / metabolism. Receptor, ErbB-4

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  • (PMID = 19017278.001).
  • [ISSN] 1365-2990
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / / A6618; United Kingdom / Cancer Research UK / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / RNA, Messenger; EC 2.7.10.1 / ERBB2 protein, human; EC 2.7.10.1 / ERBB4 protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-2; EC 2.7.10.1 / Receptor, ErbB-3; EC 2.7.10.1 / Receptor, ErbB-4; EC 3.4.- / Peptide Hydrolases
  • [Other-IDs] NLM/ PMC2705759; NLM/ UKMS4066
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7. Trivedi A, Hiran S: Calcified epidural hematoma in pediatric age group: A report of two cases. J Neurosci Rural Pract; 2010 Jul;1(2):89-91

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The authors present a rare case of calcified (ossified) chronic epidural hematoma developed in a six-and-a-half-year-old female patient who was operated for cerebellar astrocytoma 6 months earlier.

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  • (PMID = 21808510.001).
  • [ISSN] 0976-3155
  • [Journal-full-title] Journal of neurosciences in rural practice
  • [ISO-abbreviation] J Neurosci Rural Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3139356
  • [Keywords] NOTNLM ; Epidural hematoma / calcified / pediatric epidural hematoma
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8. Salunke P, Badhe P, Sharma A: Cerebellar glioblastoma multiforme with non-contiguous grade 2 astrocytoma of the temporal lobe in the same individual. Neurol India; 2010 Jul-Aug;58(4):651-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar glioblastoma multiforme with non-contiguous grade 2 astrocytoma of the temporal lobe in the same individual.
  • Magnetic resonance imaging showed a diffuse non-enhancing lesion in the temporal lobe and insula and another non-contigous well defined enhancing lesion in the cerebellum.
  • The lesions were decompressed; first the temporal lesion and then the cerebellar lesion.
  • Histopathology revealed grade II astrocytoma in the temporal lobe and glioblastoma multiforme in the cerebellum.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Glioblastoma / complications. Temporal Lobe / pathology

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  • (PMID = 20739816.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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9. Daszkiewicz P, Maryniak A, Roszkowski M, Barszcz S: Long-term functional outcome of surgical treatment of juvenile pilocytic astrocytoma of the cerebellum in children. Childs Nerv Syst; 2009 Jul;25(7):855-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term functional outcome of surgical treatment of juvenile pilocytic astrocytoma of the cerebellum in children.
  • PURPOSE: Increasing incidence of pediatric brain tumors and improving survival rates encouraged us to assess long-term functional outcome of patients with cerebellar juvenile pilocytic astrocytoma (JPA).
  • CONCLUSIONS: Long-term functional treatment outcome of cerebellar JPA is relatively favorable, in spite of permanent neurological deficits and emotional disorders in over half of the patients.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Cerebellum / surgery. Child. Child, Preschool. Education. Female. Follow-Up Studies. Humans. Infant. Male. Mood Disorders / etiology. Nervous System Diseases / etiology. Parents / psychology. Patient Satisfaction. Surveys and Questionnaires. Survival. Treatment Outcome. Young Adult

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  • [Cites] J Neurosurg. 1999 Feb;90(2):265-73 [9950497.001]
  • [Cites] Neurol Neurochir Pol. 2005 May-Jun;39(3):202-6 [15981157.001]
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  • (PMID = 19418058.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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10. Josan VA, Timms CD, Rickert C, Wallace D: Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report. J Neurosurg; 2007 Jul;107(1 Suppl):66-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report.
  • Central precocious puberty secondary to a cerebellar astrocytoma is extremely rare.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Puberty, Precocious / etiology
  • [MeSH-minor] Cerebellum / pathology. Cerebellum / surgery. Child, Preschool. Diagnosis, Differential. Dominance, Cerebral. Estradiol / blood. Female. Gonadal Steroid Hormones / blood. Humans. Magnetic Resonance Imaging. Menstruation / physiology

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  • (PMID = 17644924.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gonadal Steroid Hormones; 4TI98Z838E / Estradiol
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11. Strazzer S, Zucca C, Fiocchi I, Genitori L, Castelli E: Epilepsy and neuropsychologic deficit in a child with cerebellar astrocytoma. J Child Neurol; 2006 Sep;21(9):817-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epilepsy and neuropsychologic deficit in a child with cerebellar astrocytoma.
  • We report the case of a 32-month-old female patient presenting with cerebellar pilocytic astrocytoma with epileptic seizures, psychomotor delay, and severe language delay.
  • Usually, the typical onset of cerebellar tumor is characterized by raised intracranial pressure and cerebellar incoordination.
  • A review of the few cases reported in the literature evidencing epileptic seizures symptomatic of a focal, nondegenerative mass limited to the cerebellum is included.
  • Moreover, a discussion about the cerebellar contribution to nonmotor functions in children is presented, in particular following tumor resection.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Developmental Disabilities / etiology. Epilepsy / etiology

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  • (PMID = 16970895.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants
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12. Saad A, Mo J, Miles L, Witte D: Granular cell astrocytoma of the cerebellum: report of the first case. Am J Clin Pathol; 2006 Oct;126(4):602-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell astrocytoma of the cerebellum: report of the first case.
  • It extensively infiltrated the cerebellum and was composed, predominantly, of large cells with eosinophilic granular cytoplasm.
  • Of the 49 cases of granular cell astrocytomas reported to date, none have involved the cerebellum.
  • The tumor described herein represents the first case of cerebellar granular cell astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Granular Cell Tumor / pathology
  • [MeSH-minor] Cerebellum / pathology. Child. Fatal Outcome. Female. Humans. Immunocompromised Host. Magnetic Resonance Imaging. Neoplasm Staging

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  • (PMID = 16938663.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Vassilyadi M, Shamji MF, Tataryn Z, Keene D, Ventureyra E: Postoperative surveillance magnetic resonance imaging for cerebellar astrocytoma. Can J Neurol Sci; 2009 Nov;36(6):707-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Postoperative surveillance magnetic resonance imaging for cerebellar astrocytoma.
  • This study evaluated the utility and yield of such strategy for pilocytic and non-pilocytic cerebellar astrocytomas.
  • METHODS: A 20-year retrospective review was performed of patients undergoing resection of cerebellar astrocytoma at a single institution.
  • RESULTS: Twenty-eight patients with pilocytic (n=15) and non-pilocytic (n=13) astrocytoma underwent 34 craniotomies, with total resection in 19 cases.
  • No differences in NMS ratio were observed between pilocytic and non-pilocytic astrocytoma subtypes.
  • DISCUSSION: This study illustrates pediatric patients with low-grade cerebellar astrocytomas undergoing total resection may not benefit from routine surveillance neuroimaging, primarily because of low recurrence likelihood.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Magnetic Resonance Imaging

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  • (PMID = 19960748.001).
  • [ISSN] 0317-1671
  • [Journal-full-title] The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • [ISO-abbreviation] Can J Neurol Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
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14. López JI, Scheithauer BW, Giannini C, Torp SH: Concurrent solitary fibrous tumor and low-grade fibrillary astrocytoma of the cerebellum. Clin Neuropathol; 2010 Sep-Oct;29(5):301-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent solitary fibrous tumor and low-grade fibrillary astrocytoma of the cerebellum.
  • OBJECTIVE: We report the clinicopathologic features of a solitary fibrous tumor (SFT) having undergone malignant transformation and being intimately associated with a WHO Grade II astrocytoma.
  • CONCLUSION: The biologic basis for the association of SFT and astrocytoma is unknown.
  • [MeSH-major] Astrocytoma / diagnosis. Astrocytoma / epidemiology. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / epidemiology. Solitary Fibrous Tumors / diagnosis. Solitary Fibrous Tumors / epidemiology

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  • (PMID = 20860893.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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15. Muzumdar D, Ventureyra EC: Tonsillar herniation and cervical syringomyelia in association with posterior fossa tumors in children: a case-based update. Childs Nerv Syst; 2006 May;22(5):454-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CASE REPORT: We describe a case of a pilocytic astrocytoma of the cerebellum in a 13-year-old girl who presented with clinical features of progressively worsening raised intracranial pressure and secondary tonsillar herniation and cervical syringomyelia.
  • In addition, the cerebellar tonsils herniated down to the C2 level, and there was a centrally located syrinx from C2-T1.
  • CONCLUSIONS: The occurrence of tonsillar herniation and syringomyelia in association with a slow growing benign tumor like pilocytic astrocytoma of the cerebellum is uncommon.
  • [MeSH-major] Astrocytoma. Hernia / etiology. Infratentorial Neoplasms / complications. Palatine Tonsil / pathology. Syringomyelia / etiology

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  • (PMID = 16397818.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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16. Steinbok P, Poskitt K, Hendson G: Spontaneous regression of cerebellar astrocytoma after subtotal resection. Childs Nerv Syst; 2006 Jun;22(6):572-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous regression of cerebellar astrocytoma after subtotal resection.
  • CASE REPORT: The authors report a child in whom residual cerebellar astrocytoma after surgical resection was documented on serial computed tomography scans to undergo gradual complete regression spontaneously over a period of 11 years.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Neoplasm Recurrence, Local / pathology. Neurosurgery / methods

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  • (PMID = 16552566.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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17. Lim SC, Hong R, Kim YS, Jang SJ: Large cystic cavernous angioma of the cerebellum mimicking pilocytic astrocytoma. J Neurooncol; 2006 Sep;79(2):169-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large cystic cavernous angioma of the cerebellum mimicking pilocytic astrocytoma.
  • They are generally located supratentorially with a rare incidence in the cerebellum.
  • CONCLUSION: When a large cystic lesion is present in the cerebellum, preoperative radiological and intraoperative findings led to misdiagnosis.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Central Nervous System Cysts / diagnosis. Cerebellum / pathology. Hemangioma, Cavernous, Central Nervous System / diagnosis

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  • (PMID = 16821089.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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18. Huber JF, Bradley K, Spiegler BJ, Dennis M: Long-term effects of transient cerebellar mutism after cerebellar astrocytoma or medulloblastoma tumor resection in childhood. Childs Nerv Syst; 2006 Feb;22(2):132-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term effects of transient cerebellar mutism after cerebellar astrocytoma or medulloblastoma tumor resection in childhood.
  • BACKGROUND: Following cerebellar tumor resection, some patients develop transient cerebellar mutism (TCM).
  • Although the mutism resolves, it is not known whether there are long-term motor speech deficits in patients with TCM that are in excess of those in individuals with cerebellar tumors who had not developed postoperative TCM.
  • METHODS: Long-term survivors of cerebellar tumors resected in childhood who developed TCM were matched to survivors without TCM and to controls.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Medulloblastoma / surgery. Mutism / etiology. Postoperative Complications

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  • (PMID = 16155765.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P01 HD 35946
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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19. Zhao YC, Li NY, Zhou XJ, Zhou HB, Ma HH, Zhang RS: [Clinicopathologic study of pilocytic astrocytoma]. Zhonghua Bing Li Xue Za Zhi; 2008 Sep;37(9):609-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinicopathologic study of pilocytic astrocytoma].
  • OBJECTIVE: To study clinicopathologic features, treatment and prognosis of pilocytic astrocytoma (PA).
  • On postcontrast imaging examination there were 33 cases involving the cerebellum (48.5%).
  • The tumor can be mistaken as higher-grade astrocytoma when involving the subarachnoid space, and with cytological atypia, leading to unnecessary radiotherapy after surgery.
  • [MeSH-major] Astrocytoma / genetics. Brain Neoplasms / genetics. Glial Fibrillary Acidic Protein / genetics. Recurrence

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  • (PMID = 19094585.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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20. Saka E, Ozkaynak S, Tuncer R: Tongue tremor in brainstem pilocytic astrocytoma. J Clin Neurosci; 2006 May;13(4):503-6
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  • [Title] Tongue tremor in brainstem pilocytic astrocytoma.
  • The patient was diagnosed with brainstem pilocytic astrocytoma.
  • A widespread lesion of the brainstem and cerebellum was evident on cranial magnetic resonance imaging.
  • [MeSH-major] Astrocytoma / pathology. Brain Stem Neoplasms / pathology. Tongue / physiopathology. Tremor / etiology

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  • (PMID = 16678738.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
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21. Neves AM, Thompson G, Carvalheira J, Trindade JC, Rueff J, Caetano JM, Casey JW, Hermouet S: Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma. Brain Res; 2008 Jul 24;1221:108-14
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  • [Title] Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma.
  • We investigated the hypothetical role of human herpesviruses (HHVs) in tumour formation of the cerebellum.
  • Thirty-five samples of pilocytic astrocytoma and 10 control samples of cerebellum from patients who died of unrelated diseases were examined.
  • In summary, EBV was the most frequent HHV detected in pilocytic astrocytoma, but at very low levels.
  • According to the actually accepted threshold the results suggest that EBV cannot be considered responsible for tumorigenesis of pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / virology. Cerebellar Neoplasms / virology. DNA, Viral / genetics. Herpesviridae / genetics. Herpesviridae Infections / complications. Herpesviridae Infections / genetics

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  • (PMID = 18565499.001).
  • [ISSN] 0006-8993
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA, Viral; EC 2.7.7.- / DNA Polymerase III; EC 2.7.7.- / DNA polymerase A
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22. Manley S, Crooks D, Artingstall L, Buxton N, Appleton R, Riordan A, Cleary G, Pizer B: Diffuse central nervous system protoplasmic astrocytoma. Pediatr Blood Cancer; 2010 May;54(5):768-9
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  • [Title] Diffuse central nervous system protoplasmic astrocytoma.
  • Protoplasmic astrocytoma is an extremely rare form of grade II low grade glioma which usually presents as a discrete mass lesion.
  • We describe a 3-year-old female with diffuse protoplasmic astrocytoma with parenchymal involvement and leptomeningeal spread.
  • Three superficial biopsies did not give the diagnosis and this was only confirmed 8 months from presentation from a larger fourth biopsy taken deeper from the cerebellum.
  • To our knowledge this case represents the distinct presentation of protoplasmic astrocytoma presenting as extensive diffuse meningeal disease.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Meningeal Neoplasms / pathology

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  • (PMID = 20049933.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Rønning C, Sundet K, Due-Tønnessen B, Lundar T, Helseth E: Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood. Pediatr Neurosurg; 2005 Jan-Feb;41(1):15-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood.
  • Traditionally, the cerebral hemispheres have been regarded as the region of the brain responsible for cognitive functions, while the cerebellum has been considered to be primarily involved in motor functions.
  • Recent studies focus also on the possible involvement of the cerebellum in neurocognitive functions.
  • The aim of this study was to determine the neuropsychological profile of young adults treated for a posterior fossa tumor in childhood and look for possible support for the presence of the so-called 'cerebellar cognitive affective syndrome' in these patients.
  • The astrocytoma group (n = 12) had been treated for a low-grade cerebellar astrocytoma with surgery alone (mean age at surgery was 8.6 years and mean age at neuropsychological testing was 23.5 years).
  • Nonetheless, the astrocytoma group also had impaired scores compared with standard norms on measures of motor speed, attention and executive function.
  • No significant correlation between age at time of treatment and grade of neuropsychological impairment was found in the astrocytoma group, though there was a tendency that young age at time of treatment correlated with better outcome on IQ measures.
  • CONCLUSIONS: Persistent cognitive dysfunction was detected in patients treated for posterior fossa medulloblastoma and cerebellar astrocytoma.
  • The astrocytoma group was treated with surgery alone, indicating that a cerebellar lesion can result in cognitive dysfunction.
  • Thus, this study gives support to the existence of the cerebellar cognitive affective syndrome.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Cerebellum / physiopathology. Cerebellum / surgery. Cognition Disorders / etiology. Medulloblastoma / surgery

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 15886508.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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24. Tibbetts KM, Emnett RJ, Gao F, Perry A, Gutmann DH, Leonard JR: Histopathologic predictors of pilocytic astrocytoma event-free survival. Acta Neuropathol; 2009 Jun;117(6):657-65
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  • [Title] Histopathologic predictors of pilocytic astrocytoma event-free survival.
  • Pilocytic astrocytoma (PA) is the most common pediatric brain tumor.
  • Most arise in the cerebellum, but they also can develop in the brainstem and optic nerve, where gross total resection (GTR) is not possible.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology


25. Ammerman JM, Lonser RR, Oldfield EH: Posterior subtemporal transtentorial approach to intraparenchymal lesions of the anteromedial region of the superior cerebellum. J Neurosurg; 2005 Nov;103(5):783-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Posterior subtemporal transtentorial approach to intraparenchymal lesions of the anteromedial region of the superior cerebellum.
  • OBJECT: To overcome the limitations associated with surgical approaches that have been described for accessing intraparenchymal lesions of the anteromedial region of the superior cerebellum, the authors used a posterior subtemporal transtentorial approach to remove tumors in this region.
  • In this paper they describe the surgical technique that they used as well as the operative findings and clinical outcomes observed in patients who underwent resection of tumors in the anteromedial superior cerebellum.
  • METHODS: The consecutive patients with anteromedial superior cerebellar tumors who underwent resection performed using the posterior subtemporal transtentorial approach at the National Institutes of Health were included in this study.
  • Three patients (two men and one woman) with anteromedial superior cerebellar tumors (two hemangioblastomas and one pilocytic astrocytoma) underwent resection via this approach.
  • CONCLUSIONS: The posterior subtemporal transtentorial approach provides excellent access to the anteromedial superior cerebellar region.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Cerebellum / surgery. Hemangioblastoma / surgery. Neurosurgical Procedures

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  • [CommentIn] J Neurosurg. 2006 May;104(5):854; author reply 855-6 [16703898.001]
  • [CommentIn] J Neurosurg. 2006 May;104(5):854-5; author reply 855-6 [16703899.001]
  • [CommentIn] J Neurosurg. 2005 Nov;103(5):776-7; discussion 777 [16304978.001]
  • (PMID = 16304980.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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26. Kumar AJ, Leeds NE, Kumar VA, Fuller GN, Lang FF, Milas Z, Weinberg JS, Ater JL, Sawaya R: Magnetic resonance imaging features of pilocytic astrocytoma of the brain mimicking high-grade gliomas. J Comput Assist Tomogr; 2010 Jul;34(4):601-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Magnetic resonance imaging features of pilocytic astrocytoma of the brain mimicking high-grade gliomas.
  • OBJECTIVE: The typical magnetic resonance/computed tomographic imaging appearance of pilocytic astrocytoma (PA) is that of a cyst with an intensely enhancing mural nodule.
  • Tumor locations consisted of the following: optic chiasm (22), lateral ventricle (3), thalamus (12), basal ganglia (1), cerebral hemisphere (10), corpus callosum (2), brain stem (26), fourth ventricle (1), and cerebellum (23).
  • CONCLUSIONS: It is important to recognize the aggressive imaging appearance of PA (grade 1 astrocytoma) because it can be mistaken for high-grade gliomas and may thus lead to inappropriate therapy.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Glioma / diagnosis. Magnetic Resonance Imaging / methods

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  • (PMID = 20657231.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Walid MS, Troup EC: Cerebellar anaplastic astrocytoma in a teenager with Ollier Disease. J Neurooncol; 2008 Aug;89(1):59-62
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  • [Title] Cerebellar anaplastic astrocytoma in a teenager with Ollier Disease.
  • We are presenting a young patient with Ollier Disease and high-grade astrocytoma.
  • Brain MRI with contrast showed a 41 x 55 mm mass in the posterior fossa with spotty enhancement, which pathology proved to be anaplastic astrocytoma.
  • [MeSH-major] Astrocytoma / etiology. Astrocytoma / pathology. Cerebellar Neoplasms / etiology. Cerebellar Neoplasms / pathology. Cerebellum / pathology. Enchondromatosis / complications

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  • (PMID = 18414790.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / PTH1R protein, human; 0 / Receptor, Parathyroid Hormone, Type 1; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
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28. Lin M, Smith T, Beran RG: Crossed cerebellar hyperperfusion on ictal FDG PET in astrocytoma. J Clin Neurosci; 2009 Apr;16(4):603-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Crossed cerebellar hyperperfusion on ictal FDG PET in astrocytoma.
  • Crossed cerebellar hyperperfusion (CCH) is a rare phenomenon and reflects the close anatomical and functional relationship between the frontal brain region and its mediated remote effect on the contralateral cerebellum via the corticopontocerebellar pathway.
  • The scan performed shortly after seizure onset demonstrated intense metabolic activity in the right superior frontal lobe and in the contralateral cerebellar hemisphere consistent with CCH.
  • [MeSH-major] Astrocytoma / radionuclide imaging. Cerebellar Neoplasms / radionuclide imaging. Cerebellum. Cerebrovascular Circulation. Fluorodeoxyglucose F18. Positron-Emission Tomography / methods

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  • (PMID = 19231196.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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29. Francesco F, Maurizio I, Stefano C, Marina S, Ugo S, Massimo S: Trigeminal nerve root entry zone pilocytic astrocytoma in an adult: a rare case of an extraparenchymal tumor. J Neurooncol; 2010 Apr;97(2):285-90
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  • [Title] Trigeminal nerve root entry zone pilocytic astrocytoma in an adult: a rare case of an extraparenchymal tumor.
  • Gliomas in the CPA are rare and quite often are the exophytic extension of primary brain stem or cerebellar tumors.
  • We describe a pilocytic astrocytoma of the CPA that was found to arise from the proximal portion of trigeminal nerve without any anatomic continuity with the brain stem and the cerebellum.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Cranial Nerve Neoplasms / pathology. Trigeminal Nerve Diseases / pathology

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  • (PMID = 19820900.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Pascual-Castroviejo I, Pascual-Pascual SI, Viaño J, Carceller F, Gutierrez-Molina M, Morales C, Frutos-Martinez R: Posterior fossa tumors in children with neurofibromatosis type 1 (NF1). Childs Nerv Syst; 2010 Nov;26(11):1599-603
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  • Four of them had astrocytomas but only in one case was the tumour primarily cerebellar while the tumour was primarily of the brain stem with invasion of the adjacent regions of one or both cerebellar hemispheres in three patients.
  • The patient with primary cerebellar astrocytoma is apparently cured 7 years after the removal of the tumour.
  • The patients with the brain stem tumours extending to the cerebellum, showed a chronic slowly progressive cerebellar disease, but remain alive at age of more than 20 years (one was lost to follow-up).
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / diagnosis. Astrocytoma / mortality. Astrocytoma / pathology. Astrocytoma / surgery. Brain Stem Neoplasms / diagnosis. Brain Stem Neoplasms / mortality. Brain Stem Neoplasms / pathology. Brain Stem Neoplasms / surgery. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / mortality. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Magnetic Resonance Imaging. Magnetic Resonance Spectroscopy. Male. Medulloblastoma / diagnosis. Medulloblastoma / mortality. Medulloblastoma / pathology. Medulloblastoma / surgery. Retrospective Studies. Survival Rate. Tomography, X-Ray Computed. Young Adult

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  • [CommentIn] Childs Nerv Syst. 2010 Nov;26(11):1491; author reply 1493 [20853110.001]
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  • (PMID = 20464401.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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31. Dunn IF, Agarwalla PK, Papanastassiou AM, Butler WE, Smith ER: Multiple pilocytic astrocytomas of the cerebellum in a 17-year-old patient with neurofibromatosis type I. Childs Nerv Syst; 2007 Oct;23(10):1191-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple pilocytic astrocytomas of the cerebellum in a 17-year-old patient with neurofibromatosis type I.
  • The most common of these are hypothalamic-optic gliomas, followed by brainstem and cerebellar pilocytic astrocytomas.
  • The most frequent combination in NFI patients with more than one pilocytic astrocytoma is optic tract/hypothalamic and brainstem.
  • This report presents the first documented case, to our knowledge, of multiple pilocytic astrocytomas in the cerebellum of a patient with NF1.
  • CONCLUSION: The finding of multiple cerebellar pilocytic astrocytomas in a patient with NF1 is important because it expands the spectrum of presentations for patients with NF1 and also highlights specific diagnostic and therapeutic challenges faced by the treating physicians.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Neurofibromatosis 1 / pathology

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  • (PMID = 17457593.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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32. White JB, Piepgras DG, Scheithauer BW, Parisi JE: Rate of spontaneous hemorrhage in histologically proven cases of pilocytic astrocytoma. J Neurosurg; 2008 Feb;108(2):223-6
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  • [Title] Rate of spontaneous hemorrhage in histologically proven cases of pilocytic astrocytoma.
  • There were no locations more susceptible to hemorrhage than any other, although no bleeding occurred within the cerebellum.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Cerebral Hemorrhage / etiology


33. Saunders DE, Phipps KP, Wade AM, Hayward RD: Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma. J Neurosurg; 2005 Mar;102(2 Suppl):172-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma.
  • OBJECT: The authors sought to evaluate surveillance strategies for the detection and monitoring of residual and recurrent disease in children with cerebellar low-grade astrocytomas (CLGAs) treated surgically or with radiotherapy.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Magnetic Resonance Imaging. Neoplasm, Residual / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Cerebellum / pathology. Cerebellum / radiography. Cerebellum / surgery. Child. Child, Preschool. Disease Progression. Female. Follow-Up Studies. Humans. Infant. Male. Neoplasm Recurrence, Local / epidemiology. Neoplasm Staging. Postoperative Care. Remission, Spontaneous. Time Factors

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  • (PMID = 16156227.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Tchoghandjian A, Fernandez C, Colin C, El Ayachi I, Voutsinos-Porche B, Fina F, Scavarda D, Piercecchi-Marti MD, Intagliata D, Ouafik L, Fraslon-Vanhulle C, Figarella-Branger D: Pilocytic astrocytoma of the optic pathway: a tumour deriving from radial glia cells with a specific gene signature. Brain; 2009 Jun;132(Pt 6):1523-35
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  • [Title] Pilocytic astrocytoma of the optic pathway: a tumour deriving from radial glia cells with a specific gene signature.
  • These tumours affect preferentially the cerebellum (benign clinical course) and the optic pathway, especially the hypothalamo-chiasmatic region (poor prognosis).
  • We used the microarray technique to compare the transcriptional profiles of five hypothalamo-chiasmatic and six cerebellar pilocytic astrocytomas.
  • Results demonstrate that cerebellar and hypothalamo-chiasmatic pilocytic astrocytomas are two genetically distinct and topography-dependent entities.
  • [MeSH-major] Astrocytoma / diagnosis. Optic Nerve Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Astrocytes / metabolism. Cell Proliferation. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / genetics. Cerebellar Neoplasms / pathology. Child. Child, Preschool. DNA, Neoplasm / genetics. Diagnosis, Differential. Gene Expression Profiling / methods. Gene Expression Regulation, Neoplastic. Humans. Hypothalamus / metabolism. Infant. Middle Aged. Neoplastic Stem Cells / pathology. Neuroglia / pathology. Oligonucleotide Array Sequence Analysis / methods. Optic Chiasm / cytology. Optic Chiasm / embryology. Optic Chiasm / metabolism. Reverse Transcriptase Polymerase Chain Reaction / methods. Up-Regulation. Vimentin / metabolism. Young Adult

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  • (PMID = 19336457.001).
  • [ISSN] 1460-2156
  • [Journal-full-title] Brain : a journal of neurology
  • [ISO-abbreviation] Brain
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Vimentin
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35. Kawai H, Ishikawa T, Moroi J, Hanyu N, Sawada M, Kobayashi N, Mutou T, Hikichi K, Suzuki A, Yasui N, Yoshida Y: [Elderly patient with cerebellar malignant astrocytoma]. No Shinkei Geka; 2008 Sep;36(9):799-805
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  • [Title] [Elderly patient with cerebellar malignant astrocytoma].
  • Malignant cerebellar astrocytoma is very rare and the prognosis is extremely poor.
  • We report herein the case of an elderly patient with malignant cerebellar astrocytoma.
  • Metastatic cerebellar tumor was diagnosed on first admission, based on a past history of colon cancer treated by surgery and magnetic resonance imaging (MRI) findings supporting the diagnosis of metastasis.
  • MRI revealed a cystic mass in the right cerebellar hemisphere, and the lesion was removed by right suboccipital craniotomy.
  • The tumor represented malignant astrocytoma.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery

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  • (PMID = 18800635.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 19
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36. Huber JF, Bradley K, Spiegler B, Dennis M: Long-term neuromotor speech deficits in survivors of childhood posterior fossa tumors: effects of tumor type, radiation, age at diagnosis, and survival years. J Child Neurol; 2007 Jul;22(7):848-54

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The cerebellum is important for the coordination of fluent speech.
  • The authors studied how childhood cerebellar tumors affect long-term neuromotor speech outcomes, including the relation between outcome and tumor type, radiation, age at diagnosis, and survival years.
  • Videotaped speech samples of child and adult long-term survivors of childhood cerebellar astrocytoma (nonradiated) and medulloblastoma (radiated) tumors and healthy controls were analyzed by 2 speech pathologists for ataxic dysarthria, dysfluency, and speech rate.
  • Medulloblastoma and astrocytoma survivors were each significantly more dysfluent than controls but did not differ from each other.
  • Ataxic dysarthric speech characteristics are more frequent in radiated survivors of medulloblastoma tumors than nonradiated survivors of astrocytoma tumors.
  • Dysfluent and slow speech occur in cerebellar tumor survivors, regardless of tumor type and radiation history.
  • Cerebellar tumors in childhood limit speech rate in adulthood.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Dysarthria / etiology. Infratentorial Neoplasms / complications. Medulloblastoma / complications

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  • (PMID = 17715277.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P01 HD 35946
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
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37. Kano T, Ikota H, Wada H, Iwasa S, Kurosaki S: A case of an anaplastic ependymoma with gliosarcomatous components. Brain Tumor Pathol; 2009;26(1):11-7
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  • Computed tomography revealed a large cystic lesion with a mural nodule-like mass homogeneously enhanced with contrast medium in the right cerebellum.
  • The tumor was removed, and pathological studies revealed a cerebellar astrocytoma corresponding to World Health Organization grade II.
  • When she was 35 years old, or 6 years after the surgery, magnetic resonance imaging revealed a recurrence of the tumor in the right cerebellum, and subtotal removal of the recurrent tumor was performed.
  • Thereafter, at 39 years of age, or 4 years after radiation therapy, magnetic resonance imaging again revealed a recurrence of the tumor, which was heterogeneously enhanced with gadoliniumdiethylenetriamine pentaacetic acid in the right cerebellum.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Ependymoma / pathology. Gliosarcoma / pathology
  • [MeSH-minor] Adult. Astrocytoma / pathology. Astrocytoma / surgery. Female. Glial Fibrillary Acidic Protein / metabolism. Headache / etiology. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Paraffin Embedding. Tomography, X-Ray Computed

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  • (PMID = 19408092.001).
  • [ISSN] 1861-387X
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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38. Hashiguchi K, Morioka T, Samura K, Miyagi Y, Yoshida F, Nagata S, Sasaki T: Medial temporal lobe epilepsy associated with misplacement of a ventricular shunting catheter. J Clin Neurosci; 2008 Aug;15(8):939-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • At 8 years of age, the patient had undergone total removal of a cerebellar astrocytoma and placement of a Torkildsen's ventriculo-cisternal shunt for obstructive hydrocephalus.

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  • (PMID = 18502644.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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39. Nicolardi L, DeAngelis LM: Response to chemotherapy of a radiation-induced glioblastoma multiforme. J Neurooncol; 2006 May;78(1):55-7
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  • RESULTS: Our patient developed a left occipital GBM 35 years after a left cerebellar astrocytoma was treated with surgery and radiation therapy (4500 rad).
  • [MeSH-minor] Adult. Astrocytoma / radiotherapy. Astrocytoma / surgery. Child, Preschool. Humans. Magnetic Resonance Imaging. Male. Radiotherapy, Adjuvant / adverse effects

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  • (PMID = 16314941.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; U68WG3173Y / Carmustine
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40. Richter S, Schoch B, Kaiser O, Groetschel H, Hein-Kropp C, Maschke M, Dimitrova A, Gizewski E, Ziegler W, Karnath HO, Timmann D: Children and adolescents with chronic cerebellar lesions show no clinically relevant signs of aphasia or neglect. J Neurophysiol; 2005 Dec;94(6):4108-20
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  • [Title] Children and adolescents with chronic cerebellar lesions show no clinically relevant signs of aphasia or neglect.
  • We studied language and visuospatial functions of 12 children and adolescents who had undergone surgery for cerebellar astrocytoma without subsequent radiation or chemotherapy and compared them with 27 age-, gender-, and education-matched healthy control subjects.
  • To study possible lateralization of the functions of the left and right cerebellar hemispheres, subjects performed several language tasks including a verb-generation task as well as standard neglect and extinction tests.
  • Three-dimensional-MR images confirmed that lesions affected cerebellar hemispheres in all children but one who had a pure vermal lesion.
  • The right cerebellar hemisphere was affected in six, the left hemisphere in four children, and both hemispheres in one child.
  • There were no signs of aphasia in the children or adolescents with cerebellar lesions.
  • Language abilities did not differ between cerebellar patients and control subjects except for small increases in reaction times in verb generation in patients with left-sided lesions.
  • Visuospatial functions were also intact in cerebellar subjects except for minor group differences in neglect tasks.
  • In sum, chronic focal cerebellar lesions acquired in childhood or youth do not result in persistent language disorders or clinically significant signs of spatial neglect or extinction.
  • [MeSH-major] Aphasia / physiopathology. Astrocytoma / physiopathology. Attention / physiology. Cerebellar Neoplasms / physiopathology. Language. Perceptual Disorders / physiopathology

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  • (PMID = 16033937.001).
  • [ISSN] 0022-3077
  • [Journal-full-title] Journal of neurophysiology
  • [ISO-abbreviation] J. Neurophysiol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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41. Keezer MR, Del Maestro R: Radiation-induced cavernous hemangiomas: case report and literature review. Can J Neurol Sci; 2009 May;36(3):303-10

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  • The case of a 51-year-old man diagnosed with two acquired cavernous hemangiomas 17 years after cranial irradiation for a cerebellar astrocytoma is reported.

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  • (PMID = 19534329.001).
  • [ISSN] 0317-1671
  • [Journal-full-title] The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • [ISO-abbreviation] Can J Neurol Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Canada
  • [Number-of-references] 50
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42. Koga N, Ishikawa H: [Clinical evaluation of primary position upbeat nystagmus]. Nippon Ganka Gakkai Zasshi; 2005 Apr;109(4):205-9

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  • The lesions were located mostly in the median portion of the cerebellum and medulla oblongata.
  • They were located in the median portion of the cerebellum and medulla oblongata except for one adult patient with astrocytoma.
  • CONCLUSION: The lesions were located mostly in the median portion of the cerebellum and medulla oblongata, and especially in the cerebellum in children.
  • [MeSH-minor] Adult. Aged. Astrocytoma / complications. Brain Neoplasms / complications. Cerebellum / pathology. Cerebrovascular Disorders / complications. Child. Child, Preschool. Female. Humans. Male. Medulla Oblongata / pathology. Middle Aged

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  • (PMID = 15859150.001).
  • [ISSN] 0029-0203
  • [Journal-full-title] Nippon Ganka Gakkai zasshi
  • [ISO-abbreviation] Nippon Ganka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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43. Huang H, Hara A, Homma T, Yonekawa Y, Ohgaki H: Altered expression of immune defense genes in pilocytic astrocytomas. J Neuropathol Exp Neurol; 2005 Oct;64(10):891-901
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pilocytic astrocytoma (WHO grade I) is a circumscribed, slowly growing, benign astrocytoma that most frequently develops in the cerebellar hemispheres and in midline structures and occurs predominantly in childhood and adolescence.
  • In contrast to diffusely infiltrating gliomas in adults (e.g. grade II astrocytomas, oligodendrogliomas), survival of patients with pilocytic astrocytoma is excellent after surgical intervention.
  • To search for potential molecular mechanisms underlying its benign biologic behavior, we compared gene expression profiles of pilocytic astrocytomas (8 cases) with those of normal cerebellum (4 cases), low-grade astrocytomas (WHO grade II; 15 cases), and oligodendrogliomas (WHO grade II; 17 cases) by cDNA array analysis.
  • A number of immune system-related genes such as HLA-DRalpha, HLA-DPB1, HLA-DQB1, IgG3, IgGK, FCER1G, A2M, FCRN, IFI-56K, and DAP12 were upregulated in pilocytic astrocytomas relative to normal cerebellum, grade II astrocytomas, and oligodendrogliomas.
  • [MeSH-major] Astrocytoma / genetics. Astrocytoma / immunology. Brain Neoplasms / genetics. Brain Neoplasms / immunology. Gene Expression. Immunity / genetics
  • [MeSH-minor] Adolescent. Cerebellum / metabolism. Child. Child, Preschool. Cluster Analysis. Computer Systems. Female. Gene Expression Profiling. HLA-DR Antigens / metabolism. Humans. Male. Oligodendroglioma / genetics. Oligodendroglioma / metabolism. Oligonucleotide Array Sequence Analysis. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction


44. Popple RA, Griffith HR, Sawrie SM, Fiveash JB, Brezovich IA: Implementation of talairach atlas based automated brain segmentation for radiation therapy dosimetry. Technol Cancer Res Treat; 2006 Feb;5(1):15-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We demonstrated the utility of Brains2DICOM using a test case, a 34-year-old man with diffuse astrocytoma treated with three-dimensional conformal radiotherapy.
  • Brains2 successfully applied the Talairach atlas to identify the right and left frontal, parietal, temporal, occipital, subcortical, and cerebellum regions.
  • [MeSH-minor] Adult. Anatomy, Artistic. Astrocytoma / radiotherapy. Humans. Image Processing, Computer-Assisted / methods. Magnetic Resonance Imaging / methods. Male. Medical Illustration. Neural Networks (Computer). Software

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  • (PMID = 16417398.001).
  • [ISSN] 1533-0346
  • [Journal-full-title] Technology in cancer research & treatment
  • [ISO-abbreviation] Technol. Cancer Res. Treat.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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45. Maryniak A, Roszkowski M: [Cognitive and affective disturbances in children after surgical treatment of cerebellar tumors]. Neurol Neurochir Pol; 2005 May-Jun;39(3):202-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cognitive and affective disturbances in children after surgical treatment of cerebellar tumors].
  • BACKGROUND AND PURPOSE: The cerebellum has been associated with motor control, but more recent studies have extended its contribution to other functions, such as modulation of emotions, behavioral organization or language.
  • The cerebellar cognitive affective syndrome was described primarily in adults.
  • In children, cerebellar lesions are relatively frequent and some are due to neoplasm.
  • MATERIAL AND METHODS: Cognitive and emotional functions were studied in 66 children who underwent surgery for cerebellar pilocytic astrocytoma at the Department of Neurosurgery of the Children Memorial Health Institute.
  • No significant differences between groups of children with different localization of tumor (vermis or cerebellar hemisphere) were observed.
  • CONCLUSIONS: The present study confirms the psychological deficits following cerebellar lesion in children, similar to the cerebellar cognitive affective syndrome reported in adult patients.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Cognition Disorders / etiology. Mood Disorders / etiology. Neurosurgical Procedures / adverse effects. Speech Disorders / etiology
  • [MeSH-minor] Adaptation, Psychological. Adolescent. Adult. Cerebellum / physiopathology. Cerebellum / surgery. Child. Child, Preschool. Female. Humans. Male. Memory Disorders / etiology. Neuropsychological Tests. Parent-Child Relations. Poland. Retrospective Studies

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  • (PMID = 15981157.001).
  • [ISSN] 0028-3843
  • [Journal-full-title] Neurologia i neurochirurgia polska
  • [ISO-abbreviation] Neurol. Neurochir. Pol.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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46. Fisher PG, Tihan T, Goldthwaite PT, Wharam MD, Carson BS, Weingart JD, Repka MX, Cohen KJ, Burger PC: Outcome analysis of childhood low-grade astrocytomas. Pediatr Blood Cancer; 2008 Aug;51(2):245-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Two hundred seventy-eight children (160 males; mean age 9.1 years; tumor location: 77 cerebrum, 62 cerebellum, 51 hypothalamic, 30 thalamus, 9 ventricle, 40 brainstem, and 9 spine) were assessed.
  • Among 246 specimens reviewed, diagnoses were 135 pilocytic astrocytoma (PA), 27 diffuse astrocytoma (DA), 75 unclassifiable well-differentiated astrocytoma (NOS), and 9 subependymal giant cell astrocytoma.
  • [MeSH-major] Astrocytoma / mortality. Brain Neoplasms / mortality

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  • (PMID = 18386785.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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47. Freitas MR, de Muzio SD, Pessoa RC, Stávale JN, Borges LR, Malheiros SM: [Diffuse bone marrow metastasis in cerebellar high-grade astrocytoma. A case report]. Rev Neurol; 2009 Mar 1-15;48(5):242-4
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  • [Title] [Diffuse bone marrow metastasis in cerebellar high-grade astrocytoma. A case report].
  • [Transliterated title] Metastasis difusa de la medula osea en un astrocitoma cerebeloso de alto grado. Un caso clinico.
  • INTRODUCTION: Cerebellar high-grade astrocytoma is uncommon.
  • Although more prone to present cerebrospinal fluid dissemination, the cerebellar location is not particularly related to the occurrence of extra-cranial metastases, which are also unusual in supratentorial malignant gliomas.
  • CASE REPORT: A 46 year-old man with cerebellar anaplastic astrocytoma who developed pancytopenia due to extensive bone marrow metastases.
  • [MeSH-major] Astrocytoma / pathology. Bone Marrow Neoplasms / secondary. Cerebellar Neoplasms / pathology

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  • (PMID = 19263392.001).
  • [ISSN] 1576-6578
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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48. Bassi R, Anelli V, Giussani P, Tettamanti G, Viani P, Riboni L: Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors. Glia; 2006 Apr 15;53(6):621-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors.
  • The mitogenic role of sphingosine-1-phosphate (S1P) and its involvement in basic fibroblast growth factor (bFGF)-induced proliferation were examined in primary cultures of cerebellar astrocytes.
  • These results support the view that S1P exerted a mitogenic effect on cerebellar astrocytes extracellularly, most likely through cell surface S1P receptors.
  • In agreement, mRNAs for S1P1, S1P2, and S1P3 receptors are expressed in cerebellar astrocytes (Anelli et al., 2005.
  • Cerebellum 1:129-135), efficiently inhibited S1P-induced proliferation.
  • [MeSH-major] Astrocytes / metabolism. Cell Proliferation / drug effects. Cerebellum / metabolism. Fibroblast Growth Factor 2 / pharmacology. GTP-Binding Protein alpha Subunits, Gi-Go / metabolism. Lysophospholipids / metabolism. Receptors, Lysosphingolipid / metabolism. Sphingosine / analogs & derivatives
  • [MeSH-minor] Animals. Animals, Newborn. Astrocytoma / metabolism. Astrocytoma / physiopathology. Brain Neoplasms / metabolism. Brain Neoplasms / physiopathology. Cell Transformation, Neoplastic / metabolism. Cells, Cultured. Ceramides / metabolism. Ceramides / pharmacology. DNA Replication / drug effects. DNA Replication / physiology. Enzyme Inhibitors / pharmacology. Extracellular Fluid / drug effects. Extracellular Fluid / metabolism. Extracellular Signal-Regulated MAP Kinases / drug effects. Extracellular Signal-Regulated MAP Kinases / metabolism. Gliosis / metabolism. Gliosis / physiopathology. Mitosis / drug effects. Mitosis / physiology. Phosphotransferases (Alcohol Group Acceptor) / antagonists & inhibitors. Phosphotransferases (Alcohol Group Acceptor) / metabolism. Rats. Signal Transduction / drug effects. Signal Transduction / physiology

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  • (PMID = 16470810.001).
  • [ISSN] 0894-1491
  • [Journal-full-title] Glia
  • [ISO-abbreviation] Glia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ceramides; 0 / Enzyme Inhibitors; 0 / Lysophospholipids; 0 / Receptors, Lysosphingolipid; 103107-01-3 / Fibroblast Growth Factor 2; 26993-30-6 / sphingosine 1-phosphate; EC 2.7.1.- / Phosphotransferases (Alcohol Group Acceptor); EC 2.7.1.- / sphingosine kinase; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 3.6.5.1 / GTP-Binding Protein alpha Subunits, Gi-Go; NGZ37HRE42 / Sphingosine
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49. Debono B, Derrey S, Rabehenoina C, Proust F, Freger P, Laquerrière A: Primary diffuse multinodular leptomeningeal gliomatosis: case report and review of the literature. Surg Neurol; 2006 Mar;65(3):273-82; discussion 282

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  • Histological examination revealed an anaplastic astrocytoma.
  • RESULTS: Complete neuraxis postmortem examination revealed no intraparenchymatous glioma and was conclusive for the diagnosis of primary leptomeningeal gliomatosis (astrocytic, World Health Organization grade III), with a multinodular pattern in the spinal cord, the brainstem, and the brain base with diffuse extension into the cerebellar subarachnoid spaces.
  • [MeSH-major] Astrocytoma / surgery. Meningeal Neoplasms / surgery. Neoplasms, Neuroepithelial / surgery. Peripheral Nervous System Neoplasms / surgery. Spinal Nerve Roots / surgery
  • [MeSH-minor] Brain / pathology. Cerebellum / pathology. Diagnosis, Differential. Fatal Outcome. Humans. Intracranial Pressure / physiology. Male. Meninges / pathology. Middle Aged. Neoplasm Invasiveness / pathology. Neurologic Examination. Prognosis

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  • (PMID = 16488248.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 39
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50. Quintero-Gallego EA, Gómez CM, Vaquero Casares E, Márquez J, Pérez-Santamaría FJ: Declarative and procedural learning in children and adolescents with posterior fossa tumours. Behav Brain Funct; 2006;2:9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: This quasi-experimental study was designed to assess two important learning types - procedural and declarative--in children and adolescents affected by posterior fossa tumours (astrocytoma vs. medulloblastoma), given that memory has an important impact on the child's academic achievement and personal development.
  • The results support the role of the cerebellum in the early phase of procedural learning.

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  • (PMID = 16539720.001).
  • [ISSN] 1744-9081
  • [Journal-full-title] Behavioral and brain functions : BBF
  • [ISO-abbreviation] Behav Brain Funct
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1435762
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51. Docking KM, Ward EC, Murdoch BE: Language outcomes subsequent to treatment of brainstem tumour in childhood. NeuroRehabilitation; 2005;20(2):107-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • While the occurrence and management of brainstem tumours in children would not traditionally indicate potential direct structural impact on classical language centres, recent theories have implicated some involvement of the brainstem in a functional language and cognitive neural loop between the cerebellum and the cerebral hemispheres.
  • [MeSH-minor] Adolescent. Astrocytoma / complications. Astrocytoma / rehabilitation. Child. Child, Preschool. Ependymoma / complications. Ependymoma / rehabilitation. Female. Glioma / complications. Glioma / rehabilitation. Humans. Magnetic Resonance Imaging. Male


52. Daglioglu E, Ergungor F, Hatipoglu HG, Okay O, Dalgic A, Orhan G, Unal T: Cerebral leukoencephalopathy with calcifications and cysts operated for signs of increased intracranial pressure: case report. Surg Neurol; 2009 Aug;72(2):177-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It should be differentiated from FD or bilateral striopallidodentate calcinosis and astrocytoma.
  • CASE DESCRIPTION: We report a sporadic case operated for signs of increased ICP and cerebellar cystic mass.
  • The patient had symmetric bilateral cerebral and cerebellar calcifications, white matter edema, and a secondary thalamic cyst as well.
  • After resection of the cerebellar mass, clinical picture returned to normal and edematous findings on MRI resolved in addition to a decrease in size of the thalamic lesion on follow-up.
  • [MeSH-major] Calcinosis / diagnosis. Central Nervous System Cysts / diagnosis. Cerebellar Diseases / complications. Cerebellar Diseases / diagnosis. Cerebellum / pathology. Intracranial Hypertension / etiology. Intracranial Hypertension / surgery

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  • (PMID = 18514290.001).
  • [ISSN] 1879-3339
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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53. Shamsadini S, Varesvazirian M, Shamsadini A: Urticaria and lip fasciculation may be prodromal signs of brain malignancy. Dermatol Online J; 2006;12(3):23
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  • CT scan revealed a brain tumor adjacent to the cerebellum, which was diagnosed as astrocytoma grade II.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Fasciculation / etiology. Lip. Urticaria / etiology

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  • (PMID = 16638437.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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54. Stokland T, Liu JF, Ironside JW, Ellison DW, Taylor R, Robinson KJ, Picton SV, Walker DA: A multivariate analysis of factors determining tumor progression in childhood low-grade glioma: a population-based cohort study (CCLG CNS9702). Neuro Oncol; 2010 Dec;12(12):1257-68
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  • From the cohort of 798 patients, 639 patients were eligible, with a median age 6.71 years (0.26-16.75 years); 49% were males; 15.9% had neurofibromatosis type 1, 63.7% pilocytic astrocytoma, 5.9% fibrillary astrocytoma, 4.2% mixed neuronal-glial tumors, and 3.6% others; 21.1% were diagnosed clinically.
  • Anatomically implicated were 31.6% cerebellum, 24.6% chiasma/hypothalamus, 16.0% cerebral hemispheres, 9.9% brain stem, 6.1% other supratentorial midline structures, 5.9% optic nerve only, 4.5% spinal cord, and 1.4% others.
  • Multivariate analysis identified young age, fibrillary astrocytoma, and extent of surgical resection as significant independent risk factors for progression.

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  • (PMID = 20861086.001).
  • [ISSN] 1523-5866
  • [Journal-full-title] Neuro-oncology
  • [ISO-abbreviation] Neuro-oncology
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3018938
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55. Zuzak TJ, Poretti A, Drexel B, Zehnder D, Boltshauser E, Grotzer MA: Outcome of children with low-grade cerebellar astrocytoma: long-term complications and quality of life. Childs Nerv Syst; 2008 Dec;24(12):1447-55
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  • [Title] Outcome of children with low-grade cerebellar astrocytoma: long-term complications and quality of life.
  • OBJECTS: To study the long-term outcome of surgically treated low-grade cerebellar astrocytomas in children.
  • CONCLUSION: Childhood low-grade cerebellar astrocytomas have an excellent cure rate by tumor surgery alone.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Quality of Life

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  • (PMID = 18690461.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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56. Howes TL, Buatti JM, Kirby PA, Carlisle TL, Ryken TC: Radiation induced adult medulloblastoma: a case report. J Neurooncol; 2006 Nov;80(2):191-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Our patient is a 61 year old woman treated with cranial irradiation 15 years previously for a low grade astrocytoma in the left posterior temporal lobe that was recently diagnosed with medulloblastoma in the right cerebellum.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Medulloblastoma / etiology. Neoplasms, Radiation-Induced / pathology
  • [MeSH-minor] Astrocytoma / radiotherapy. Brain Neoplasms / radiotherapy. Craniotomy. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Neurosurgical Procedures. Temporal Lobe / pathology

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  • (PMID = 16710747.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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57. Maruyama K, Morita A, Shibahara J, Nakazato Y, Kirino T: Multifocal pilocytic astrocytomas with ependymal differentiation in the bilateral medial temporal lobes: case report. Neurol Med Chir (Tokyo); 2005 Aug;45(8):411-4
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  • The histological diagnosis was pilocytic astrocytoma with ependymal differentiation and a MIB-1 staining index of up to 8.0%.
  • Pilocytic astrocytoma usually presents as a solitary mass in the cerebellum or optic pathway with low proliferative activity, but should be included in the differential diagnosis of multifocal tumors arising in the bilateral temporal lobes.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Temporal Lobe / pathology

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  • (PMID = 16127260.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / MIB-1 antibody
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58. El-Bahy K: Telovelar approach to the fourth ventricle: operative findings and results in 16 cases. Acta Neurochir (Wien); 2005 Feb;147(2):137-42; discussion 142

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  • Subtotal removal was achieved in the remaining patients (31.25%); three ependymomas, one medulloblastoma, and one anaplastic astrocytoma.
  • Cerebellar mutism was not observed in any patient and there was no mortality.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellum / pathology. Cerebellum / surgery. Fourth Ventricle / pathology. Fourth Ventricle / surgery. Neurosurgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / pathology. Astrocytoma / surgery. Cerebellar Ataxia / etiology. Cerebellar Ataxia / pathology. Cerebellar Ataxia / physiopathology. Child. Choroid Plexus / pathology. Choroid Plexus / surgery. Cranial Fossa, Posterior / surgery. Dermoid Cyst / pathology. Dermoid Cyst / surgery. Ependymoma / pathology. Ependymoma / surgery. Female. Humans. Magnetic Resonance Imaging. Male. Medulloblastoma / pathology. Medulloblastoma / surgery. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Papilloma, Choroid Plexus / pathology. Papilloma, Choroid Plexus / surgery. Postoperative Complications / etiology. Postoperative Complications / pathology. Postoperative Complications / physiopathology. Retrospective Studies. Treatment Outcome

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  • (PMID = 15605202.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Austria
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59. Horbinski C, Hamilton RL, Nikiforov Y, Pollack IF: Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas. Acta Neuropathol; 2010 May;119(5):641-9
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  • Pilocytic astrocytoma (PA) is the most common glioma in the pediatric population.
  • An institutional cohort of 147 PAs (118 with outcome data) from both cerebellar and non-cerebellar locations (spine, diencephalon, midbrain, brainstem, and cortex) was utilized in this study.
  • Loss of heterozygosity on 17p13 correlated with increased risk of recurrence in cerebellar tumors.
  • BRAF gene rearrangements were more common in cerebellar tumors than non-cerebellar tumors and associated with classic biphasic histology in the cerebellum.
  • Additionally, deletion on 17p13 may be an adverse prognostic biomarker in cerebellar tumors.
  • [MeSH-major] Astrocytoma / genetics. Brain / pathology. Brain Neoplasms / genetics. Proto-Oncogene Proteins B-raf / genetics. Spinal Cord Neoplasms / genetics

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  • (PMID = 20044755.001).
  • [ISSN] 1432-0533
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / R01 NS37704
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
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60. Yeaney GA, O'Connor SM, Jankowitz BT, Hamilton RL: A 16-year-old male with a cerebellar mass. Brain Pathol; 2009 Jan;19(1):167-70

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  • [Title] A 16-year-old male with a cerebellar mass.
  • MRI revealed a cystic and solid, enhancing midline cerebellar lesion.
  • An infiltrating component resembling diffuse astrocytoma could be found in areas.
  • The pathologic diagnosis was pleomorphic xanthoastrocytoma (PXA) of the cerebellum.
  • This case is one of sixteen cerebellar PXAs reported in the literature.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis

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  • (PMID = 19076785.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Reticulin; 0 / Vimentin
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61. Toyoda T, Ochiai K, Hatai H, Murakami M, Ono E, Kimura T, Umemura T: Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma. Vet Pathol; 2006 May;43(3):294-301
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  • [Title] Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma.
  • Fowl glioma-inducing virus (FGV), which belongs to subgroup A of avian leukosis virus (ALV), shows tumorigenicity and pathogenicity, mainly in the nervous system, and causes astrocytoma and perineurioma.
  • Apart from these neoplasms, cerebellar anomaly was found in chickens infected with FGV in ovo.
  • The study reported here describes the morphologic characteristics of the affected cerebellum.
  • The cerebellar anomaly included diffuse depletion of granular cells of the internal granular layer (IGL), remnants of the external granular layer (EGL), and disorganization of the Purkinje cell layer.
  • These cerebellar changes were observed in all birds except one.
  • These results suggested that the cerebellar anomaly was hypoplasia, principally resulting from the apoptosis of granular cells in the EGL and ML caused by FGV infection and that the cell loss induced obstruction of granular cell migration and disarrangement of Bergmann's fibers in the ML.
  • [MeSH-major] Avian Leukosis Virus / pathogenicity. Cerebellar Diseases / veterinary. Cerebellum / pathology. Glioma / veterinary. Poultry Diseases / pathology. Poultry Diseases / virology

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  • (PMID = 16672576.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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62. Agir H, Sen C, Muezzinoglu B, Isl E: Report of a radiation-induced leiomyosarcoma arising from the posterior neck. J Craniofac Surg; 2007 Sep;18(5):1018-20
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  • Herein, we report a 48-year-old male patient who developed leiomyosarcoma in his posterior neck region, which was previously radiated due to a cerebellar astrocytoma.
  • [MeSH-minor] Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Humans. Male. Middle Aged

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  • (PMID = 17912075.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Saikali S, Le Strat A, Heckly A, Stock N, Scarabin JM, Hamlat A: Multicentric pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1. Case report and review of the literature. J Neurosurg; 2005 Feb;102(2):376-81
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  • Although the occipital lesion was cured surgically, the cerebellar tumor recurred three times and underwent malignant transformation into an anaplastic oligodendroglioma.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Neurofibromatosis 1 / surgery
  • [MeSH-minor] Adult. Brain / pathology. Brain / surgery. Cell Transformation, Neoplastic / pathology. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellum / pathology. Cerebellum / surgery. Disease Progression. Female. Humans. Image Enhancement. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Occipital Lobe / pathology. Occipital Lobe / surgery. Oligodendroglioma / pathology


64. De Jesús ML, Sallés J, Meana JJ, Callado LF: Characterization of CB1 cannabinoid receptor immunoreactivity in postmortem human brain homogenates. Neuroscience; 2006 Jun 30;140(2):635-43

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  • These data were confirmed by blotting experiments carried out with human U373MG astrocytoma cells as a positive control for CB1 expression and wild-type CHO cells as negative control.
  • Important differences in the anatomical distribution of CB1 were observed with regard to that described previously in monkey and rat; in the human brain, CB1 levels were higher in cortex and caudate than in the cerebellum.

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  • (PMID = 16563642.001).
  • [ISSN] 0306-4522
  • [Journal-full-title] Neuroscience
  • [ISO-abbreviation] Neuroscience
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cannabinoid Receptor Modulators; 0 / Receptor, Cannabinoid, CB1
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65. Rueckriegel SM, Driever PH, Blankenburg F, Lüdemann L, Henze G, Bruhn H: Differences in supratentorial damage of white matter in pediatric survivors of posterior fossa tumors with and without adjuvant treatment as detected by magnetic resonance diffusion tensor imaging. Int J Radiat Oncol Biol Phys; 2010 Mar 1;76(3):859-66
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  • PATIENTS AND METHODS: Seventeen medulloblastoma (MB) patients who had received surgery and adjuvant treatment, 13 pilocytic astrocytoma (PA) patients who had been treated only with surgery, and age-matched healthy control subjects underwent magnetic resonance imaging on a 3-Tesla system.
  • RESULTS: Compared with control subjects, FA values of MB patients were significantly decreased in the cerebellar midline structures, in the frontal lobes, and in the callosal body.
  • Fractional anisotropy values of the PA patients were not only decreased in cerebellar hemispheric structures as expected, but also in supratentorial parts of the brain, with a distribution similar to that in MB patients.
  • CONCLUSIONS: Neurotoxic mechanisms that are present in PA patients (e.g., internal hydrocephalus and damaged cerebellar structures affecting neuronal circuits) contribute significantly to the alteration of supratentorial white matter in pediatric posterior fossa tumor patients.
  • [MeSH-major] Astrocytoma. Brain / pathology. Diffusion Magnetic Resonance Imaging / methods. Infratentorial Neoplasms. Medulloblastoma. Survivors
  • [MeSH-minor] Adolescent. Anisotropy. Axons. Case-Control Studies. Cerebellum / drug effects. Cerebellum / pathology. Cerebellum / radiation effects. Chemotherapy, Adjuvant / adverse effects. Child. Child, Preschool. Cranial Irradiation / adverse effects. Female. Humans. Leukoencephalopathies / etiology. Leukoencephalopathies / pathology. Male. Radiotherapy, Adjuvant / adverse effects

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  • [Copyright] Copyright (c) 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19540067.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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66. Horská A, Laclair A, Mohamed M, Wells CT, McNutt T, Cohen KJ, Wharam M, Mahone EM, Kates W: Low cerebellar vermis volumes and impaired neuropsychologic performance in children treated for brain tumors and leukemia. AJNR Am J Neuroradiol; 2010 Sep;31(8):1430-7
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  • [Title] Low cerebellar vermis volumes and impaired neuropsychologic performance in children treated for brain tumors and leukemia.
  • BACKGROUND AND PURPOSE: Injury of the cerebellar vermis may occur in children with brain malignancies.
  • Because the vermis is involved in motor and cognitive functioning, the goal of this prospective longitudinal study was to evaluate treatment-related changes in vermal volumes and neuropsychologic performance in children receiving brain radiation of the cerebellum.
  • In addition to radiation, the presence of brain malignancies and preradiation treatment may be important factors affecting cerebellar vermis tissue.

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  • (PMID = 20448013.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / HD-24061; United States / NCRR NIH HHS / RR / UL1 RR025005; United States / NICHD NIH HHS / HD / HD024061-12; United States / NICHD NIH HHS / HD / P30 HD024061; United States / NINDS NIH HHS / NS / R01 NS04285; United States / NCRR NIH HHS / RR / UL1-RR025005; United States / NCRR NIH HHS / RR / UL1 RR025005-01; United States / NINDS NIH HHS / NS / R01 NS042851-04; United States / NICHD NIH HHS / HD / P30HD024061-16; United States / NINDS NIH HHS / NS / NS042851-04; United States / NICHD NIH HHS / HD / P30 HD024061-12
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS266264; NLM/ PMC3040108
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67. Yang JW, Kang SU, Engidawork E, Rodrigo R, Felipo V, Lubec G: Mass spectrometrical analysis of galectin proteins in primary rat cerebellar astrocytes. Neurochem Res; 2006 Jul;31(7):945-55
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  • [Title] Mass spectrometrical analysis of galectin proteins in primary rat cerebellar astrocytes.
  • Using two-dimensional gel electrophoresis coupled to tandem mass spectrometry, the present work aimed to identify and characterize galectins in primary rat cerebellar astrocytes.
  • As these family members are linked to human astrocytic tumors, their reliable detection in astrocytes by proteomic techniques would enable us to further understand their role in neural development, injury, and regeneration in general and astrocytoma in particular.
  • [MeSH-major] Astrocytes / metabolism. Cerebellum / metabolism. Galectins / metabolism. Spectrometry, Mass, Electrospray Ionization / methods. Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods

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  • (PMID = 16804752.001).
  • [ISSN] 0364-3190
  • [Journal-full-title] Neurochemical research
  • [ISO-abbreviation] Neurochem. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Galectins
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68. Grahovac G, Tomac D, Lambasa S, Zoric A, Habek M: Cerebellar glioblastomas: pathophysiology, clinical presentation and management. Acta Neurochir (Wien); 2009 Jun;151(6):653-7
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  • [Title] Cerebellar glioblastomas: pathophysiology, clinical presentation and management.
  • Glioblastoma multiforme usually affects the cerebral hemispheres with the peak age of onset in the sixth or seventh decade, while cerebellar glioblastoma multiforme is a rare tumour especially in younger patients.
  • Most result from de-differentiation from low grade astrocytoma (secondary glioblastoma) or can develop de novo (primary glioblastoma).
  • We report a 28 year old patient with primary multi-focal cerebellar glioblastoma multiforme and review the pathophysiology, clinical presentation, diagnosis and treatment of cerebellar glioblastomas.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Genetic Predisposition to Disease / genetics. Glioblastoma / pathology. Mutation / genetics. Tumor Suppressor Protein p53 / genetics
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Cerebellum / pathology. Cerebellum / radiography. Cerebellum / surgery. Fatal Outcome. Female. Fourth Ventricle / pathology. Fourth Ventricle / surgery. Headache / etiology. Humans. Hydrocephalus / etiology. Intracranial Hypertension / etiology. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Neurosurgical Procedures / methods. Reoperation. Tomography, X-Ray Computed. Vomiting / etiology

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  • (PMID = 19319469.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Protein p53
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69. Ahmed N, Bhurgri Y, Sadiq S, Shakoor KA: Pediatric brain tumours at a tertiary care hospital in Karachi. Asian Pac J Cancer Prev; 2007 Jul-Sep;8(3):399-404
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  • The mean age for all cases, both genders was 8.8 years (95% CI 7.9; 9.6) with a marginal variation for cases occurring in the cerebrum and cerebellum.
  • The morphological distribution of cases was astrocytoma (28 cases, 34.6%), primitive neuroectodermal tumor or PNET (40 cases; 49.4%), ependymoma (8 cases, 10%), mixed glioma (4 cases; 5%) and a case of oligodendroglioma.
  • The morphological categorization of supratentorial tumors was astrocytoma (17 cases; 63%), ependymoma (5 cases; 18.5%), mixed glioma (2 cases; 7.4%).
  • The 17 supratentorial astrocytoma were sub-categorized as follows - pilocytic astrocytoma (5 cases; 29.4%), grade II astrocytoma (6 cases; 35.3%); grade III astrocytoma (2 cases; 11.8%), anaplastic astrocytoma (1 case; 5.9%) and glioblastoma multiforme (3 cases; 17.7%).
  • The morphological categorization of infratentorial tumors was astrocytoma (11 cases; 20.4%), medulloblastoma (38 cases; 70.4%), ependymoma (3 cases; 5.6%) and mixed glioma - astroependymoma (2 cases, 3.7%).
  • The morphological sub-categorization of infratentorial astrocytoma was pilocytic astrocytoma (7 cases, 63.6%), with gemistocytic astrocytoma, grade II, grade III and anaplastic astrocytoma comprising 1 (9.1%) case each.

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  • (PMID = 18159977.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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70. de Ribaupierre S, Ryser C, Villemure JG, Clarke S: Cerebellar lesions: is there a lateralisation effect on memory deficits? Acta Neurochir (Wien); 2008 Jun;150(6):545-50; discussion 550

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  • [Title] Cerebellar lesions: is there a lateralisation effect on memory deficits?
  • BACKGROUND: Until recently, neurosurgeons eagerly removed cerebellar lesions without consideration of future cognitive impairment that might be caused by the resection.
  • In children, transient cerebellar mutism after resection has lead to a diminished use of midline approaches and vermis transection, as well as reduced retraction of the cerebellar hemispheres.
  • The role of the cerebellum in higher cognitive functions beyond coordination and motor control has recently attracted significant interest in the scientific community, and might change the neurosurgical approach to these lesions.
  • The aim of this study was to investigate the specific effects of cerebellar lesions on memory, and to assess a possible lateralisation effect.
  • METHODS: We studied 16 patients diagnosed with a cerebellar lesion, from January 1997 to April 2005, in the "Centre Hospitalier Universitaire Vaudois (CHUV)", Lausanne, Switzerland.
  • RESULTS: Severe memory deficits in at least one modality were identified in a majority (81%) of patients with cerebellar lesions.
  • FINDINGS: These findings are consistent with findings in the literature concerning memory deficits in isolated cerebellar lesions.
  • The high percentage of patients with a cerebellar lesion who demonstrate memory deficits should lead us to assess memory in all patients with cerebellar lesions.
  • [MeSH-major] Amnesia / physiopathology. Cerebellar Neoplasms / physiopathology. Dominance, Cerebral / physiology
  • [MeSH-minor] Adolescent. Adult. Aged. Amnesia, Anterograde / diagnosis. Amnesia, Anterograde / physiopathology. Astrocytoma / diagnosis. Astrocytoma / physiopathology. Astrocytoma / surgery. Cerebellum / physiopathology. Cerebellum / surgery. Female. Follow-Up Studies. Glioblastoma / diagnosis. Glioblastoma / physiopathology. Glioblastoma / surgery. Hemangioblastoma / diagnosis. Hemangioblastoma / physiopathology. Hemangioblastoma / surgery. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / physiopathology. Hemangioma, Cavernous / surgery. Humans. Male. Medulloblastoma / diagnosis. Medulloblastoma / physiopathology. Medulloblastoma / surgery. Memory, Short-Term / physiology. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / physiopathology. Meningeal Neoplasms / surgery. Meningioma / diagnosis. Meningioma / physiopathology. Meningioma / surgery. Middle Aged. Neuropsychological Tests. Postoperative Complications / diagnosis. Postoperative Complications / physiopathology. Verbal Learning / physiology

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  • (PMID = 18512000.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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71. Kwon JW, Kim IO, Cheon JE, Kim WS, Moon SG, Kim TJ, Chi JG, Wang KC, Chung JK, Yeon KM: Paediatric brain-stem gliomas: MRI, FDG-PET and histological grading correlation. Pediatr Radiol; 2006 Sep;36(9):959-64

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In 12 patients in whom FDG-PET was undertaken, glioblastomas showed hypermetabolic or hypometabolic lesions, anaplastic astrocytomas showed no metabolic change or hypometabolic lesions and low-grade astrocytomas showed hypometabolism compared with the cerebellum.
  • FDG-PET may be helpful in differentiating between anaplastic astrocytoma and glioblastomas among high-grade tumours.

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  • (PMID = 16847598.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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72. Lee JM, Kim SH, Lee JI, Ryou JY, Kim SY: Acute comitant esotropia in a child with a cerebellar tumor. Korean J Ophthalmol; 2009 Sep;23(3):228-31
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  • [Title] Acute comitant esotropia in a child with a cerebellar tumor.
  • We report a case of acute comitant esotropia in a child with a cerebellar tumor.
  • Brain MRI showed a 5 cm mass located in the midline of the cerebellum as well as hydrocephalus.
  • The mass was completely excised and histological examination confirmed the diagnosis of pilocytic astrocytoma.
  • Therefore, acute onset comitant esotropia in a child can be the first sign of a cerebellar tumor, even without any other neurological signs and symptoms.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Esotropia / etiology

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  • (PMID = 19794955.001).
  • [ISSN] 2092-9382
  • [Journal-full-title] Korean journal of ophthalmology : KJO
  • [ISO-abbreviation] Korean J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2739968
  • [Keywords] NOTNLM ; Acute onset / Cerebellar tumor / Comitant esotropia
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73. Kirschen MP, Davis-Ratner MS, Milner MW, Chen SH, Schraedley-Desmond P, Fisher PG, Desmond JE: Verbal memory impairments in children after cerebellar tumor resection. Behav Neurol; 2008;20(1-2):39-53
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  • [Title] Verbal memory impairments in children after cerebellar tumor resection.
  • This study was designed to investigate cerebellar lobular contributions to specific cognitive deficits observed after cerebellar tumor resection.
  • Verbal working memory (VWM) tasks were administered to children following surgical resection of cerebellar pilocytic astrocytomas and age-matched controls.
  • Anatomical MRI scans were used to quantify the extent of cerebellar lobular damage from each patient's resection.
  • These data corroborate neuroimaging studies showing focal cerebellar activation during VWM paradigms, and thereby allow us to predict with greater accuracy which specific neurocognitive processes will be affected by a cerebellar tumor resection.

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  • (PMID = 19491473.001).
  • [ISSN] 0953-4180
  • [Journal-full-title] Behavioural neurology
  • [ISO-abbreviation] Behav Neurol
  • [Language] ENG
  • [Grant] United States / NIMH NIH HHS / MH / MH060234-08; United States / NIMH NIH HHS / MH / R01 MH060234; United States / NIMH NIH HHS / MH / MH060234; United States / NIMH NIH HHS / MH / R01 MH060234-08
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS124119; NLM/ PMC2745108
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74. Ehling R, Sterlacci W, Maier H, Berger T: A 45-year old male with left-sided hemihypesthesia. Brain Pathol; 2010 Mar;20(2):515-8
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  • A 45-year-old man presented with progressive brainstem and cerebellar dysfunction.
  • Stereotactic biopsies of the brainstem were performed; the findings of abundant Rosenthal fibers, interjacent spindle-shaped and gemistocytic cells partially with dark and irregularly formed nuclei favored primarily the diagnosis of a malignant astrocytoma, although a demyelinating disease could not be definitely excluded.
  • [MeSH-major] Brain Stem / pathology. Cerebellum / pathology. Hypesthesia / diagnosis. Hypesthesia / pathology. Multiple Sclerosis / diagnosis. Multiple Sclerosis / pathology

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  • (PMID = 20438473.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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75. Johnson CE, Huang YY, Parrish AB, Smith MI, Vaughn AE, Zhang Q, Wright KM, Van Dyke T, Wechsler-Reya RJ, Kornbluth S, Deshmukh M: Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues. Proc Natl Acad Sci U S A; 2007 Dec 26;104(52):20820-5
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  • In contrast, primary neurons from the cerebellum and cortex are remarkably resistant to cytosolic cytochrome c.
  • Importantly, tumor tissue from mouse models of both high-grade astrocytoma and medulloblastoma display hypersensitivity to cytochrome c when compared with surrounding brain tissue.

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  • (PMID = 18093951.001).
  • [ISSN] 1091-6490
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA102707; United States / NINDS NIH HHS / NS / R01 NS042197; United States / NCI NIH HHS / CA / CA102707; United States / NINDS NIH HHS / NS / NS42197
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / APAF1 protein, human; 0 / Apoptotic Protease-Activating Factor 1; 0 / E2F1 Transcription Factor; 9007-43-6 / Cytochromes c; EC 3.4.22.- / Caspases
  • [Other-IDs] NLM/ PMC2409225
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76. Jalali R, Mallick I, Dutta D, Goswami S, Gupta T, Munshi A, Deshpande D, Sarin R: Factors influencing neurocognitive outcomes in young patients with benign and low-grade brain tumors treated with stereotactic conformal radiotherapy. Int J Radiat Oncol Biol Phys; 2010 Jul 15;77(4):974-9
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

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  • METHODS AND MATERIALS: Twenty-eight patients (median age, 13 years) with residual/progressive brain tumors (10 craniopharyngioma, 8 cerebellar astrocytoma, 6 optic pathway glioma and 4 cerebral low-grade glioma) were treated with SCRT to a dose of 54 Gy in 30 fractions over 6 weeks.
  • [MeSH-minor] Adolescent. Astrocytoma / radiotherapy. Cerebellar Neoplasms / psychology. Cerebellar Neoplasms / radiotherapy. Child. Cognition / radiation effects. Craniopharyngioma / psychology. Craniopharyngioma / radiotherapy. Female. Humans. Male. Optic Nerve Glioma / radiotherapy. Prospective Studies. Radiotherapy, Conformal / methods. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19864079.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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77. Hamlat A, Le Strat A, Guegan Y, Ben-Hassel M, Saikali S: Cerebellar pleomorphic xanthoastrocytoma: case report and literature review. Surg Neurol; 2007 Jul;68(1):89-94; discussion 94-5
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  • [Title] Cerebellar pleomorphic xanthoastrocytoma: case report and literature review.
  • METHODS: The authors report a case of cerebellar PXA with rapid malignant transformation in a 58-year-old woman and review the rare presentations and atypical features of this tumor.
  • RESULTS: Among the "unusual" locations, the most frequent is the cerebellum with 15 cases having been described, 9 in adults, with an average age of 33 years.
  • CONCLUSIONS: The clinicopathologic features of cerebellar PXA show some differences from PXA located in the cerebral hemispheres.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 17537486.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
  • [Number-of-references] 28
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78. Behnam B, Chahlavi A, Pattisapu J, Wolfe J: TSGA10 is Specifically Expressed in Astrocyte and Over-expressed in Brain Tumors. Avicenna J Med Biotechnol; 2009 Oct;1(3):161-6

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  • In rat specimens, TSGA10 was mainly expressed in subventricular zone, hippocampus and granular layer of cerebellum of the brain.
  • The TSGA10 was strongly over-expressed in glioblastoma and astrocytoma when compared to normal human brain.

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  • [ISO-abbreviation] Avicenna J Med Biotechnol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Other-IDs] NLM/ PMC3558132
  • [Keywords] NOTNLM ; Astrocytes / Brain neoplasms / Immunohistochemistry / Neuron-glia / TSGA10 protein
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79. Paixão Becker A, de Oliveira RS, Saggioro FP, Neder L, Chimelli LM, Machado HR: In pursuit of prognostic factors in children with pilocytic astrocytomas. Childs Nerv Syst; 2010 Jan;26(1):19-28
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

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  • The most common site of tumor formation was the cerebellum (17), followed by brainstem (4), optic chiasmatic hypothalamic region (4), cerebral hemisphere (3), cervical spinal cord (2), and optic nerve (1).
  • Gross total resection (GTR) was achieved in 23 (74.1%), mainly in those with tumors located in the cerebellum and cerebral hemispheres (P = 0.02).
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Spinal Cord Neoplasms / diagnosis

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  • (PMID = 19823847.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Galectin 3; 0 / Ki-67 Antigen
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80. Essig M, Giesel F, Stieltjes B, Weber MA: [Functional imaging for brain tumors (perfusion, DTI and MR spectroscopy)]. Radiologe; 2007 Jun;47(6):513-9
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PWI allows better estimates of biological activity and aggressiveness in low grade brain tumors, and in the case of WHO grade II astrocytoma showing anaplasically transformed tumor areas, allows more rapid visu-alization and a better prediction of the course of the disease than conventional MRI diagnostics.
  • Diffusion MRI, due to the directional dependence of the diffusion, can illustrate the course and direction of the nerve fibers, as well as reconstructing the nerve tracts in the cerebrum, pons and cerebellum 3-dimensionally.

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  • (PMID = 17505814.001).
  • [ISSN] 0033-832X
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 21
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81. Richter S, Schoch B, Ozimek A, Gorissen B, Hein-Kropp C, Kaiser O, Hövel M, Wieland R, Gizewski E, Ziegler W, Timmann D: Incidence of dysarthria in children with cerebellar tumors: a prospective study. Brain Lang; 2005 Feb;92(2):153-67
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence of dysarthria in children with cerebellar tumors: a prospective study.
  • The present study investigated dysarthric symptoms in children with cerebellar tumors.
  • Ten children with cerebellar tumors and 10 orthopedic control children were tested prior and one week after surgery.
  • Localization of the cerebellar lesions were defined after manual transfer from individual 2D-MR images onto 3D images of a spatially normalized healthy brain.
  • Cerebellar children showed few and mild clinical signs of dysarthria.
  • In five cerebellar children, syllables were prolonged in the syllable repetition task after surgery.
  • The MR-analysis showed that superior paravermal cerebellar areas likely involved in dysarthria in adults (paravermal lobules HVI, Crus I) were not significantly affected.
  • In children, speech impairments appear to be rare after cerebellar surgery because tumors most commonly affect posterior-inferior and medial parts of the cerebellum while critical cerebellar regions are likely spared.
  • The results suggest a similar localization of speech functions in the cerebellum in children and adults.
  • [MeSH-major] Astrocytoma / epidemiology. Cerebellar Neoplasms / epidemiology. Dysarthria / epidemiology. Dysarthria / physiopathology

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  • (PMID = 15629489.001).
  • [ISSN] 0093-934X
  • [Journal-full-title] Brain and language
  • [ISO-abbreviation] Brain Lang
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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82. Di X: Multiple brain tumor nodule resections under direct visualization of a neuronavigated endoscope. Minim Invasive Neurosurg; 2007 Aug;50(4):227-32
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Astrocytoma / pathology. Astrocytoma / surgery. Cerebellum / pathology. Cerebellum / physiopathology. Cerebellum / surgery. Endoscopes / standards. Female. Hemangioblastoma / pathology. Hemangioblastoma / surgery. Humans. Male. Middle Aged. Minimally Invasive Surgical Procedures / instrumentation. Minimally Invasive Surgical Procedures / methods. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / prevention & control. Neoplasm Recurrence, Local / surgery. Treatment Outcome

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  • (PMID = 17948182.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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83. Chen CC, Cheng PW, Tseng HM, Young YH: Posterior cranial fossa tumors in young adults. Laryngoscope; 2006 Sep;116(9):1678-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Magnetic resonance imaging scan demonstrated space-occupying lesions at the cerebellopontine angle in 11, cerebellum in two, brainstem in two, and jugular fossa in one.
  • Diagnoses consisted of vestibular schwannoma and neurofibromatosis II in eight patients (50%), glial neoplasm (including astrocytoma, ependymoma, glioma) in four patients (25%), epidermoid cyst in three patients, and glomus jugulare tumor in one patient.

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  • (PMID = 16955003.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Arai A, Sasayama T, Tamaki M, Sakagami Y, Enoki E, Ohbayashi C, Kohmura E: Rosette-forming glioneuronal tumor of the fourth ventricle--case report. Neurol Med Chir (Tokyo); 2010;50(3):224-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Surgical resection requires care to prevent major surgical morbidities associated with lesions invading the cerebellum or brainstem.
  • [MeSH-minor] Adolescent. Astrocytoma / pathology. Female. Ganglioglioma / pathology. Humans. Rare Diseases / pathology. Rosette Formation. Treatment Outcome

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  • (PMID = 20339273.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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85. Chahine LM, Ghosh D: Essential tremor after ipsilateral cerebellar hemispherectomy: support for the thalamus as the central oscillator. J Child Neurol; 2009 Jul;24(7):861-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Essential tremor after ipsilateral cerebellar hemispherectomy: support for the thalamus as the central oscillator.
  • We present the case of a patient who developed essential tremor ipsilateral to cerebellar hemispherectomy and propose that the central oscillator in patients with essential tremor may not be the inferior olive in all cases, but rather the nucleus ventralis intermedius of the thalamus.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Cerebellum / surgery. Essential Tremor / etiology. Essential Tremor / physiopathology. Periodicity. Thalamus / physiopathology
  • [MeSH-minor] Astrocytoma / pathology. Astrocytoma / surgery. Child. Diagnosis, Differential. Female. Functional Laterality. Humans. Magnetic Resonance Imaging

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  • (PMID = 19189936.001).
  • [ISSN] 1708-8283
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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86. Larysz D, Blamek S, Larysz P, Pietras K, Mandera M: Posterior fossa brain tissue injury: developmental, neuropsychological, and neurological consequences of brain tumors in children. Acta Neurochir Suppl; 2010;106:271-4
MedlinePlus Health Information. consumer health - Neurologic Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of the study was the functional neurodevelopmental assessment of children with posterior fossa tumors, specifically examining whether tumor location in particular cerebellar structures determines particular neuropsychological deficits.
  • Histopathological diagnoses of tumors were as follows: 4 medulloblastomas, 8 pilocytic astrocytomas, 6 fibrillary astrocytomas, 1 anaplastic astrocytoma, 2 oligodendrogliomas, 4 anaplastic ependymomas, 1 choroid plexus papilloma, and 5 arachnoid cysts.
  • Our study aimed to better understand the functional anatomy of the cerebellum in the context of behavioral changes.

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  • (PMID = 19812963.001).
  • [ISSN] 0065-1419
  • [Journal-full-title] Acta neurochirurgica. Supplement
  • [ISO-abbreviation] Acta Neurochir. Suppl.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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87. Yamada K, Takeshima H, Sakurama T, Kuratsu J: Secondary cervical dystonia following stereotactic radiosurgery in a patient with thalamic glioma. Surg Neurol; 2007 Dec;68(6):665-70
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histopathologically, tumor samples manifested features of anaplastic astrocytoma.
  • Irregular-shaped lesion involving the thalamus, lenticular nuclei, midbrain, pons, and cerebellum was presented on magnetic resonance images.


88. Benesch M, Wagner S, Berthold F, Wolff JE: Primary dissemination of high-grade gliomas in children: experiences from four studies of the Pediatric Oncology and Hematology Society of the German Language Group (GPOH). J Neurooncol; 2005 Apr;72(2):179-83
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: A total of 10 patients (3.1%) (anaplastic astrocytoma: n=3, glioblastoma multiforme: n=6, diffuse intrinsic pontine glioma: n=1) had primary tumor dissemination.
  • The most frequent primary tumor sites were the cortex (n=4), followed by the ventricles (n=2), cerebellum (n=1), spinal cord (n=1), and pons (n=1).

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  • (PMID = 15925999.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Multicenter Study
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 8N3DW7272P / Cyclophosphamide; H64JRU6GJ0 / trofosfamide
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89. Adamson DC, Rasheed BA, McLendon RE, Bigner DD: Central nervous system. Cancer Biomark; 2010;9(1-6):193-210
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Other much less common sites of primary CNS tumors include the pineal region, ventricular system, cerebellum, brain stem, cranial nerves, and spinal cord.
  • Grade IV, the most malignant grade of astrocytoma, includes glioblastoma multiforme (GBM), the most common malignant primary CNS glioma in adults, which represents 51% of all CNS gliomas.

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  • (PMID = 22112477.001).
  • [ISSN] 1875-8592
  • [Journal-full-title] Cancer biomarkers : section A of Disease markers
  • [ISO-abbreviation] Cancer Biomark
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
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90. Richter S, Schoch B, Kaiser O, Groetschel H, Dimitrova A, Hein-Kropp C, Maschke M, Gizewski ER, Timmann D: Behavioral and affective changes in children and adolescents with chronic cerebellar lesions. Neurosci Lett; 2005 Jun 10-17;381(1-2):102-7
MedlinePlus Health Information. consumer health - Mood Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Behavioral and affective changes in children and adolescents with chronic cerebellar lesions.
  • The aim of the present study was to investigate if clinically relevant affective or behavioral changes as described in adults in the cerebellar affective syndrome by Schmahmann and Sherman [The cerebellar cognitive affective syndrome, Brain 121 (1998) 561-579] are likely to occur as a long-term sequelae of cerebellar vermis lesions in children.
  • Affect and behavior were assessed in children after cerebellar tumor surgery by means of experimenter ratings based on the description of the cerebellar affective syndrome and free ratings by the patients and their parents.
  • Twelve children and adolescents with a former cerebellar astrocytoma surgery without subsequent radiation or chemotherapy participated.
  • [MeSH-major] Cerebellar Diseases / complications. Cerebellar Diseases / diagnosis. Mental Disorders / diagnosis. Mental Disorders / etiology. Mood Disorders / diagnosis. Mood Disorders / etiology

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  • (PMID = 15882798.001).
  • [ISSN] 0304-3940
  • [Journal-full-title] Neuroscience letters
  • [ISO-abbreviation] Neurosci. Lett.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
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91. Mezer E, Nischal KK, Nahjawan N, MacKeen LD, Buncic JR: Hemifacial spasm as the initial manifestation of childhood cerebellar astrocytoma. J AAPOS; 2006 Oct;10(5):489-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemifacial spasm as the initial manifestation of childhood cerebellar astrocytoma.

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  • (PMID = 17070492.001).
  • [ISSN] 1091-8531
  • [Journal-full-title] Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • [ISO-abbreviation] J AAPOS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Spetzler RF: Subtemporal transtentorial approach. J Neurosurg; 2006 May;104(5):854; author reply 855-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Hemangioblastoma / surgery. Infratentorial Neoplasms / surgery. Temporal Lobe / surgery
  • [MeSH-minor] Cerebellum / surgery. Humans. Treatment Outcome

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  • [CommentOn] J Neurosurg. 2005 Nov;103(5):783-8 [16304980.001]
  • (PMID = 16703898.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Comment; Comparative Study; Letter
  • [Publication-country] United States
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