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1. Li HM, Hsu SS, Wang JS, Weng MJ, Fu JH, Chen CK, Lai PH: Cerebral pilocytic astrocytoma with spontaneous intracranial hemorrhage in adults. J Chin Med Assoc; 2008 Nov;71(11):587-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebral pilocytic astrocytoma with spontaneous intracranial hemorrhage in adults.
  • Pilocytic astrocytomas are found predominantly in the pediatric population; reports of these tumors are extremely rare in adults.
  • We report 2 cases of adult pilocytic astrocytoma with intracranial hemorrhage.
  • After surgical resection, microscopic examination of the lesions showed pilocytic astrocytomas.
  • Since pilocytic astrocytoma and other cystic tumors with mural nodule (such as hemangioblastoma) have similar findings on conventional CT and MRI, PWI is helpful in the differential diagnosis.
  • The literature on hemorrhagic pilocytic astrocytoma is also reviewed.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Cerebral Hemorrhage / etiology

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  • (PMID = 19015059.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China (Republic : 1949- )
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2. Jeong SM, Chung YG, Lee JB, Shin IY: Intracranial dissemination from spinal cord anaplastic astrocytoma. J Korean Neurosurg Soc; 2010 Jan;47(1):68-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intracranial dissemination from spinal cord anaplastic astrocytoma.
  • We report a case of intracranial dissemination developing approximately 4 months after partial removal of a spinal cord anplastic astrocytoma in a 22-year-old male.
  • The final histologic diagnosis was anaplastic astrocytoma.
  • He underwent computed tomography-guided stereotactic biopsy and histological appearance was consistent with anaplastic astrocytoma.
  • The clinical course indicates that the tumor originated in the spinal cord and extended into the subarachnoid space, first the spinal canal and later intracranial.

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  • (PMID = 20157383.001).
  • [ISSN] 1598-7876
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2817520
  • [Keywords] NOTNLM ; Anaplastic astrocytoma / Intracranial dissemination / Spinal cord
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3. Jang SY, Kong MH, Song KY, Frazee JG: Intracranial Metastases of Cervical Intramedullary Low-Grade Astrocytoma without Malignant Transformation in Adult. J Korean Neurosurg Soc; 2009 Jun;45(6):381-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intracranial Metastases of Cervical Intramedullary Low-Grade Astrocytoma without Malignant Transformation in Adult.
  • The first case of intracranial metastases of a cervical intramedullary low-grade astrocytoma without malignant transformation in adult is presented in this report.
  • Seven years ago, a 45 year-old male patient underwent biopsy to confirm pathologic characteristics and received craniocervical radiation and chemotherapy for a grade II astrocytoma in the cervical spinal cord.
  • The tumor at the cervical and brain lesions was classified as an astrocytoma (WHO grade II).
  • When a patient with low-grade astrocytoma in the spinal cord has new cranial symptoms after surgery, radiaton, and chemotherapy, the possibility of its metastasis should be suspected because it can spread to the intracranial cavity even without malignant transformation as shown in this case.

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  • (PMID = 19609424.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2711238
  • [Keywords] NOTNLM ; Astrocytoma / Cranial metastases / Intramedullary / Spinal cord tumor
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4. De Tommasi A, Occhiogrosso G, De Tommasi C, Luzzi S, Cimmino A, Ciappetta P: A polycystic variant of a primary intracranial leptomeningeal astrocytoma: case report and literature review. World J Surg Oncol; 2007;5:72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A polycystic variant of a primary intracranial leptomeningeal astrocytoma: case report and literature review.
  • BACKGROUND: Primary leptomeningeal astrocytomas are rare intracranial tumors.
  • The literature reports only fifteen cases of solitary primary intracranial leptomeningeal astrocytomas.
  • CASE PRESENTATION: The authors report the case of a seventy-eight year-old woman with a polycystic variant of a solitary primary intracranial leptomeningeal astrocytoma.
  • CONCLUSION: A new case of a solitary primitive intracranial leptomeningeal astrocytoma of a rare polycystic variant is reported.
  • [MeSH-major] Arachnoid / pathology. Astrocytoma / pathology. Astrocytoma / surgery. Meningeal Neoplasms / pathology. Meningeal Neoplasms / surgery

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  • (PMID = 17587463.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 37
  • [Other-IDs] NLM/ PMC1934909
  • [General-notes] NLM/ Original DateCompleted: 20070810
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5. Shibahara I, Kanamori M, Kumabe T, Endo H, Sonoda Y, Ogawa Y, Watanabe M, Tominaga T: Hemorrhagic onset of pilocytic astrocytoma and pilomyxoid astrocytoma. Brain Tumor Pathol; 2009;26(1):1-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemorrhagic onset of pilocytic astrocytoma and pilomyxoid astrocytoma.
  • The incidence of hemorrhagic onset in pilocytic astrocytoma and pilomyxoid astrocytoma, and the clinical and histological characteristics, were compared to other types of neuroepithelial tumors or nonhemorrhagic pilocytic astrocytoma by retrospective review of 445 consecutive neuroepithelial tumors treated at our institute.
  • Hemorrhagic onset was observed in 4 of 35 (11.4%) patients with pilocytic astrocytoma and pilomyxoid astrocytoma, with higher incidence than in glioblastoma (3.9%), anaplastic oligodendroglioma (7.7%), and anaplastic ependymoma (7.1%).
  • The hemorrhagic onset occurred in 2 patients with sporadic pilocytic astrocytoma, 1 with pilocytic astrocytoma associated with neurofibromatosis type 1, and 1 with pilomyxoid astrocytoma.
  • Hemorrhagic onset of pilocytic astrocytoma and pilomyxoid astrocytoma is not as uncommon as was previously thought, so pilocytic astrocytoma or pilomyxoid astrocytoma should be considered in the differential diagnosis of patients with brain tumors manifesting as hemorrhagic onset.
  • [MeSH-major] Astrocytoma / complications. Astrocytoma / pathology. Brain Neoplasms / complications. Brain Neoplasms / pathology. Intracranial Hemorrhages / etiology. Intracranial Hemorrhages / pathology

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  • (PMID = 19408090.001).
  • [ISSN] 1861-387X
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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6. Niculescu CE, Stănescu L, Popescu M, Niculescu D: Supratentorial pilocytic astrocytoma in children. Rom J Morphol Embryol; 2010;51(3):577-80
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  • [Title] Supratentorial pilocytic astrocytoma in children.
  • The authors describe the case of a child aged 2 years and 4 months with increased intracranial pressure, symptomatology accompanied by rapid deterioration of general condition.
  • Histopathological examination revealed the typical grade I pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Supratentorial Neoplasms / pathology

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  • (PMID = 20809042.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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7. Samuelson C, Forman KM, Smith S: Idiopathic thrombocytopenic purpura associated with an astrocytoma. BMJ Case Rep; 2010;2010

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Idiopathic thrombocytopenic purpura associated with an astrocytoma.
  • We present the case of an 8-year-old girl with chronic idiopathic thrombocytopenic purpura (ITP) and a short history suggestive of raised intracranial pressure.
  • She underwent treatment with intravenous immunoglobulin (IVIg) and steroids to increase her platelet count, followed by excision of the lesion, which was found to be a benign pilocytic astrocytoma.

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  • (PMID = 22419950.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028124
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8. Tsutsumi S, Higo T, Kondo A, Abe Y, Yasumoto Y, Ito M: Atypical cervical astrocytoma manifesting as occipitalgia. Neurol Med Chir (Tokyo); 2007 Aug;47(8):371-4
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  • [Title] Atypical cervical astrocytoma manifesting as occipitalgia.
  • A 23-year-old female presented with chronic occipitalgia without signs of increased intracranial pressure followed by worsening headache and slight gait unsteadiness.
  • Histological examination identified diffuse astrocytoma.
  • Cervical astrocytoma of subpial location is a very rare cause of headache in adults.
  • [MeSH-major] Astrocytoma / complications. Astrocytoma / pathology. Headache / etiology. Spinal Cord / pathology. Spinal Cord Neoplasms / complications. Spinal Cord Neoplasms / pathology

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  • (PMID = 17721055.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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9. Fernandez A, Karavitaki N, Ansorge O, Fazal-Sanderson V, Wass JA: Acromegaly and anaplastic astrocytoma: coincidence or pathophysiological relation? Pituitary; 2008;11(3):325-30
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  • [Title] Acromegaly and anaplastic astrocytoma: coincidence or pathophysiological relation?
  • Insulin-like growth factor type I (IGF-I) is an important promoter in the tumorigenesis of several extracranial and intracranial neoplasms.
  • We report the case of a 28-year-old man who presented simultaneously with acromegaly and an anaplastic astrocytoma, which had rapidly progressed from a low-grade astrocytoma.
  • The coexistence of systemic IGF-I hypersecretion with a quick progression in the histopathological grade of the astrocytoma raises the compelling question of whether the clinical behavior of the astrocytic tumor was influenced by the acromegalic status.
  • The role of IGF-I signaling in the pathogenesis of astrocytic-cell tumors and the experience with therapeutic strategies addressing this pathway in astrocytomas are also discussed.
  • [MeSH-major] Acromegaly / complications. Astrocytoma / complications. Brain Neoplasms / complications

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  • (PMID = 18000757.001).
  • [ISSN] 1386-341X
  • [Journal-full-title] Pituitary
  • [ISO-abbreviation] Pituitary
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ergolines; 0 / Peptides, Cyclic; 0G3DE8943Y / lanreotide; 51110-01-1 / Somatostatin; 67763-96-6 / Insulin-Like Growth Factor I; LL60K9J05T / cabergoline
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10. Darwish B, Arbuckle S, Kellie S, Besser M, Chaseling R: Desmoplastic infantile ganglioglioma/astrocytoma with cerebrospinal metastasis. J Clin Neurosci; 2007 May;14(5):498-501
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic infantile ganglioglioma/astrocytoma with cerebrospinal metastasis.
  • Desmoplastic infantile ganglioglioma and astrocytoma (DIG/DIA) are rare intracranial tumours of early childhood that involve superficial cerebral cortex and leptomeninges.


11. Lyons MK: Pilocytic astrocytoma with spontaneous intracranial hemorrhages in an elderly adult. Clin Neurol Neurosurg; 2007 Jan;109(1):76-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pilocytic astrocytoma with spontaneous intracranial hemorrhages in an elderly adult.
  • Pilocytic astrocytomas are relatively uncommon tumors found predominantly in the pediatric population.
  • This is a report of a 75-year-old man presenting with two spontaneous intracranial hemorrhages and subsequent resection of a pilocytic astrocytoma.
  • A review of the literature summarizes the current field of knowledge of adult pilocytic astrocytomas in the setting of intracranial hemorrhage.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Intracranial Hemorrhages / etiology

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  • (PMID = 16621238.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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12. Porter A, Lyons MK, Wingerchuk DM, Bosch EP: Spinal cord astrocytoma presenting as "idiopathic" intracranial hypertension. Clin Neurol Neurosurg; 2006 Dec;108(8):787-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal cord astrocytoma presenting as "idiopathic" intracranial hypertension.
  • Increased intracranial pressure is rarely seen in association with spinal tumors.
  • We describe a young, non-obese man who presented with increased intracranial pressure, papilledema and visual obscuration.
  • Multiple cerebrospinal fluid (CSF) examinations with normal or minimally elevated CSF protein lead to the initial diagnosis of idiopathic intracranial hypertension.
  • Open biopsy confirmed a grade 3 fibrillary astrocytoma.
  • The suspected mechanisms of spinal tumors causing increased intracranial pressure are reviewed as well as three other cases of spinal astrocytomas previously reported in the literature that presented with papilledema and increased intracranial pressure without hydrocephalus.
  • This case illustrates that increased intracranial pressure may in exceptional cases of spinal tumors precede the more typical myelopathic presentation by months and mimic idiopathic intracranial hypertension.
  • [MeSH-major] Astrocytoma / diagnosis. Pseudotumor Cerebri / etiology. Spinal Cord Neoplasms / diagnosis

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  • (PMID = 16298472.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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13. Uro-Coste E, Ssi-Yan-Kai G, Guilbeau-Frugier C, Boetto S, Bertozzi AI, Sevely A, Lolmede K, Delisle MB: Desmoplastic infantile astrocytoma with benign histological phenotype and multiple intracranial localizations at presentation. J Neurooncol; 2010 May;98(1):143-9
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  • [Title] Desmoplastic infantile astrocytoma with benign histological phenotype and multiple intracranial localizations at presentation.
  • Desmoplastic infantile astrocytoma (DIA) and desmoplastic infantile ganglioglioma (DIG) are rare intracranial tumors that mostly occur in the first 2 years of life and involve superficial cerebral cortex.
  • We report an original observation of a desmoplastic infantile astrocytoma in a 5-year-old boy with multiple localizations on initial presentation, including the unusual subtentorial region.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology

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  • (PMID = 20012157.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Rudnick JD, Phuphanich S, Chu R, Mazer M, Wang H, Serrano N, Francisco M, Black KL, Wheeler C, Yu J: A phase I trial of surgical resection with biodegradable carmustine (BCNU) wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma. J Clin Oncol; 2009 May 20;27(15_suppl):2033

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  • The histology included 3 newly diagnosed glioblastoma multiforme (GBM), 8 recurrent GBM, 2 newly diagnosed anaplastic astrocytoma (AA), and 2 recurrent AA.
  • Immunological data is pending to determine potential synergy of dendritic cell vaccination with intracranial chemotherapy.

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  • (PMID = 27964627.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Kumar R, Kamdar D, Madden L, Hills C, Crooks D, O'Brien D, Greenman J: Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients. Oncol Rep; 2006 Jun;15(6):1513-6
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  • [Title] Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients.
  • Patients were divided into various groups depending on their histological diagnosis: meningioma (n=11), anaplastic astrocytoma (n=4) and glioblastoma multiforme (GBM; n=46).
  • Significant reduction in serum IL-12 was seen in all groups as compared with the controls: meningioma, p=0.03; anaplastic astrocytoma, p<0.001; and GBM, p<0.001.
  • Conversely, serum IL-10 was significantly increased in anaplastic astrocytoma, p=0.02, and GBM, p=0.03.
  • This study shows that patients with advanced primary intracranial malignancies have decreased circulating IL-12 and increased circulating IL-10, demonstrating that brain tumours have a major systemic effect on the immune system.
  • [MeSH-major] Astrocytoma / immunology. Brain Neoplasms / immunology. Glioblastoma / immunology. Interleukin-10 / blood. Interleukin-12 / blood. Meningioma / immunology. Th1 Cells / immunology. Th2 Cells / immunology


16. Ho BL, Lieu AS, Hsu CY: Hemiparkinsonism secondary to an infiltrative astrocytoma. Neurologist; 2008 Jul;14(4):258-61
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  • [Title] Hemiparkinsonism secondary to an infiltrative astrocytoma.
  • Brain computed tomography failed to reveal an intracranial lesion.
  • Histopathologic findings confirmed the diagnosis of high-grade astrocytoma.
  • [MeSH-major] Astrocytoma / complications. Astrocytoma / pathology. Brain Neoplasms / complications. Brain Neoplasms / pathology. Parkinsonian Disorders / etiology

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  • (PMID = 18617854.001).
  • [ISSN] 1074-7931
  • [Journal-full-title] The neurologist
  • [ISO-abbreviation] Neurologist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Kitagawa M, Sato T, Ishizaki R, Saiki M: [Resolution of migraine with aura by removing pilocytic astrocytoma of the occipital lobe]. No Shinkei Geka; 2006 Jan;34(1):59-64
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  • [Title] [Resolution of migraine with aura by removing pilocytic astrocytoma of the occipital lobe].
  • Here we report a case of pilocytic astrocytoma in the right occipital lobe presenting as migraine with aura.
  • Total removal of the tumor (pilocytic astrocytoma, WHO grade 1) relieved her migraine completely.
  • But this is the first report of occipital pilocytic astrocytoma presenting as migraine with aura.
  • As for other brain tumors manifesting migraine, all of them had focal neurological deficits or symptoms associated with increased intracranial pressure (ICP).
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Migraine with Aura / etiology. Occipital Lobe
  • [MeSH-minor] Adult. Female. Humans. Intracranial Hypertension / etiology

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  • (PMID = 16440698.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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18. Cheong JH, Kim CH, Kim JM, Oh YH: Transformation of intracranial anaplastic astrocytoma associated with neurofibromatosis type I into gliosarcoma: case report. Clin Neurol Neurosurg; 2010 Oct;112(8):701-6
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  • [Title] Transformation of intracranial anaplastic astrocytoma associated with neurofibromatosis type I into gliosarcoma: case report.
  • We report a rare case with gliosarcomatous recurrence of anaplastic astrocytoma with neurofibromatosis type 1 (NF-1) followed by chemoradiation therapy.
  • Histopathology of the tumor showed findings corresponding with anaplastic astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Gliosarcoma / pathology. Neoplasm Recurrence, Local / pathology. Neurofibromatosis 1 / pathology

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  • [Copyright] (c) 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20466481.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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19. Bongiorni L, Arroyo HA, Lubienicki F: [Subependymal nodules-sudependymal giant cell astrocytoma complex in children with tuberous sclerosis]. Medicina (B Aires); 2009;69(1 Pt 1):8-14
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  • [Title] [Subependymal nodules-sudependymal giant cell astrocytoma complex in children with tuberous sclerosis].
  • [Transliterated title] Complejo nódulo subependimario-astrocitoma subependimario gigantocelular en niños con esclerosis tuberosa.
  • The object of this paper is to describe the imaging and clinical characteristics of subependymal nodule (SN) - subependymal giant cell astrocytoma (SGCA) complex in tuberous sclerosis and analyze its evolution in order to attempt early detection and the prevention of intracranial hypertension.
  • Fifteen patients (68%) were operated with symptoms of intracranial hypertension.
  • The imaging and clinical follow-up of any subependymal lesion close to the foramen of Monro will permit, at a presymptomatic stage, an anticipation of surgical treatment thus reducing intracranial hypertension incidence.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Ventricles / pathology. Tuberous Sclerosis / pathology
  • [MeSH-minor] Adolescent. Cerebral Ventricle Neoplasms / pathology. Cerebral Ventricle Neoplasms / radiography. Cerebral Ventricle Neoplasms / surgery. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Hydrocephalus / etiology. Infant. Intellectual Disability / etiology. Intracranial Hypertension / prevention & control. Male


20. Radulović D: [Natural history of supratentorial low-grade astrocytoma: case report]. Srp Arh Celok Lek; 2006 Nov-Dec;134(11-12):537-40
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  • [Title] [Natural history of supratentorial low-grade astrocytoma: case report].
  • Low-grade astrocytomas comprise a group of primary brain neoplasms with relatively low anaplastic potential, although through time they tend to behave more aggressively.
  • This report presents a natural history of a patient with low grade astrocytoma.
  • The described patient with low-grade astrocytoma lived without any oncological treatment eight years and four months from the time when diagnosis was made until intracranial herniation.
  • The natural history of disease in presented patient indicated that rational therapeutic strategy, for low-grade astrocytoma with epilepsy only, would be deferral of surgery until the time of manifestation of neurological or radiological deterioration.
  • [MeSH-major] Astrocytoma. Brain Neoplasms. Parietal Lobe

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  • (PMID = 17304770.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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21. Fu JB, Parsons HA, Shin KY, Guo Y, Konzen BS, Yadav RR, Smith DW: Comparison of functional outcomes in low- and high-grade astrocytoma rehabilitation inpatients. Am J Phys Med Rehabil; 2010 Mar;89(3):205-12
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  • [Title] Comparison of functional outcomes in low- and high-grade astrocytoma rehabilitation inpatients.
  • OBJECTIVES: To compare inpatient rehabilitation outcomes between patients with low- and high-grade astrocytoma.
  • A high-grade (21 of 443 patients) and low-grade astrocytoma (21 of 24 patients) group were matched on three of five criteria in the order of importance: area of brain involvement (divided into left cerebral, right cerebral, midline and/or bilateral cerebral, and infratentorial), single vs. multiple intracranial neurosurgical procedures, age (within 10 yrs), period of rehabilitation admission (within 3 yrs), and sex.
  • The high-grade group had significantly (P < 0.05) higher total gain and longer stay in inpatient rehabilitation (mean +/- standard deviation, 21.7 +/- 10.1 vs. 13.0 +/- 9.3 and 13 +/- 7.1 day vs. 9 +/- 6.2 days, respectively) than did the low-grade astrocytoma group.
  • CONCLUSIONS: Compared with patients with low-grade astrocytoma, patients with high-grade astrocytoma had higher total functional independence measure gain but also longer lengths of stay.

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  • (PMID = 20068429.001).
  • [ISSN] 1537-7385
  • [Journal-full-title] American journal of physical medicine & rehabilitation
  • [ISO-abbreviation] Am J Phys Med Rehabil
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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22. Lee CS, Huh JS, Sim KB, Kim YW: Cerebellar pilocytic astrocytoma presenting with intratumor bleeding, subarachnoid hemorrhage, and subdural hematoma. Childs Nerv Syst; 2009 Jan;25(1):125-8
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  • [Title] Cerebellar pilocytic astrocytoma presenting with intratumor bleeding, subarachnoid hemorrhage, and subdural hematoma.
  • INTRODUCTION: Massive intracranial hemorrhage is a very rare initial presentation of cerebellar pilocytic astrocytomas.
  • There are no reports in the medical literature on a cerebellar pilocytic astrocytoma presenting with intratumor bleeding (ITB), subarachnoid hemorrhage (SAH), and subdural hematoma (SDH).
  • Microscopic examination of tissue sections revealed a pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Hematoma, Subdural / etiology. Subarachnoid Hemorrhage / etiology

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  • (PMID = 18629510.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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23. Oka F, Yamashita Y, Kumabe T, Tominaga T: Total resection of a hemorrhagic tectal pilocytic astrocytoma--case report. Neurol Med Chir (Tokyo); 2007 May;47(5):219-21
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  • [Title] Total resection of a hemorrhagic tectal pilocytic astrocytoma--case report.
  • A 21-year-old man presented with a hemorrhagic pilocytic astrocytoma of the tectal plate manifesting as sudden onset of severe headache, vertigo, nausea, and vomiting.
  • The histological diagnosis was pilocytic astrocytoma.
  • Tectal plate pilocytic astrocytoma is rarely associated with hemorrhage but should be considered in the differential diagnosis of intracranial hemorrhage with acute presentation.
  • [MeSH-major] Astrocytoma / pathology. Astrocytoma / surgery. Brain Neoplasms / pathology. Brain Neoplasms / surgery. Intracranial Hemorrhages / etiology. Tectum Mesencephali

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  • (PMID = 17527049.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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24. Zhi F, Chen X, Wang S, Xia X, Shi Y, Guan W, Shao N, Qu H, Yang C, Zhang Y, Wang Q, Wang R, Zen K, Zhang CY, Zhang J, Yang Y: The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma. Eur J Cancer; 2010 Jun;46(9):1640-9
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  • [Title] The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma.
  • In the present study, the miRNA expression profile was examined in astrocytoma, a malignant and prevalent intracranial tumour in adults.
  • METHODS: We screened the expression profile of 200 miRNAs in a training sample set consisting of 84 astrocytoma samples and 20 normal adjacent tissue (NAT) samples using the method of stem-loop quantitative RT-PCR.
  • The significantly altered miRNAs were validated in another independent sample set consisting of 40 astrocytoma samples and 40 NAT samples.
  • The correlation of the miRNA levels with survival in astrocytoma samples was estimated by performing Kaplan-Meier survival analysis and univariate/multivariate Cox proportional hazard regression analysis.
  • RESULTS: After a two-phase selection and validation process, seven miRNAs were found to have a significantly different expression profile in astrocytoma samples upon comparison to the NAT samples.
  • The down-regulation of hsa-miR-137 in astrocytomas was shown to be associated with advanced clinical stages of this disease.
  • CONCLUSIONS: Our results suggest a great potential for the use of miRNA profiling as a powerful diagnostic and prognostic marker in defining the signature of astrocytomas and in predicting the post-surgical outcome.
  • [MeSH-major] Astrocytoma / metabolism. Biomarkers, Tumor / metabolism. Brain Neoplasms / metabolism. MicroRNAs / metabolism

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  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20219352.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MIRN106 microRNA, human; 0 / MIRN21 microRNA, human; 0 / MIrn181 microRNA, human; 0 / MicroRNAs
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25. Raju GP, Urion DK, Sahin M: Neonatal subependymal giant cell astrocytoma: new case and review of literature. Pediatr Neurol; 2007 Feb;36(2):128-31
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  • [Title] Neonatal subependymal giant cell astrocytoma: new case and review of literature.
  • Subependymal giant cell astrocytomas are one of the three major intracranial lesions found in tuberous sclerosis complex.
  • Subependymal giant cell astrocytomas are typically slow-growing tumors of mixed glioneuronal lineage which can become aggressive and cause obstructive hydrocephalus usually in older children and adolescents.
  • Neonatal subependymal giant cell astrocytomas are extremely rare, and their natural history and prognosis are poorly understood.
  • This report investigates an extremely large neonatal subependymal giant cell astrocytoma which was initially identified in utero at 19 weeks of gestation in a high-risk pregnancy with no family history of tuberous sclerosis complex.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Magnetic Resonance Imaging

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  • (PMID = 17275668.001).
  • [ISSN] 0887-8994
  • [Journal-full-title] Pediatric neurology
  • [ISO-abbreviation] Pediatr. Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 16
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26. Josan VA, Timms CD, Rickert C, Wallace D: Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report. J Neurosurg; 2007 Jul;107(1 Suppl):66-8
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  • [Title] Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report.
  • In about 20 to 30% of cases there is an intracranial mass lesion.
  • Central precocious puberty secondary to a cerebellar astrocytoma is extremely rare.
  • There was no clinical or radiological evidence of raised intracranial pressure.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Puberty, Precocious / etiology

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  • (PMID = 17644924.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gonadal Steroid Hormones; 4TI98Z838E / Estradiol
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27. Strazzer S, Zucca C, Fiocchi I, Genitori L, Castelli E: Epilepsy and neuropsychologic deficit in a child with cerebellar astrocytoma. J Child Neurol; 2006 Sep;21(9):817-20
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  • [Title] Epilepsy and neuropsychologic deficit in a child with cerebellar astrocytoma.
  • We report the case of a 32-month-old female patient presenting with cerebellar pilocytic astrocytoma with epileptic seizures, psychomotor delay, and severe language delay.
  • Usually, the typical onset of cerebellar tumor is characterized by raised intracranial pressure and cerebellar incoordination.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Developmental Disabilities / etiology. Epilepsy / etiology

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  • (PMID = 16970895.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants
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28. Dashti SR, Robinson S, Rodgers M, Cohen AR: Pineal region giant cell astrocytoma associated with tuberous sclerosis: case report. J Neurosurg; 2005 Apr;102(3 Suppl):322-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pineal region giant cell astrocytoma associated with tuberous sclerosis: case report.
  • Cortical tubers and subependymal nodules are the characteristic intracranial lesions of tuberous sclerosis.
  • Subependymal giant cell astrocytomas, typically located adjacent to the foramen of Monro, can enlarge and cause symptomatic ventricular obstruction.
  • Pathological examination showed a giant cell astrocytoma.
  • To the authors' knowledge, this is the first reported case of tuberous sclerosis associated with a giant cell astrocytoma of the pineal region.
  • [MeSH-major] Astrocytoma / complications. Astrocytoma / surgery. Pinealoma / complications. Pinealoma / surgery. Tuberous Sclerosis / complications

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  • (PMID = 15881760.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. French PJ, Barlow A, Barlow P, Jampana RV, Stewart W: A case of pilomyxoid astrocytoma presenting with CSF rhinorrhoea in a 15-year-old. Br J Neurosurg; 2009;23(5):545-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of pilomyxoid astrocytoma presenting with CSF rhinorrhoea in a 15-year-old.
  • We report a pilomyxoid astrocytoma (PMA) presenting with CSF rhinorrhoea in a 15-year-old.
  • This uncommon, recently described entity typically presents in infancy with focal neurological or endocrine symptoms, has distinctive histologic features and displays a more aggressive behaviour than pilocytic astrocytoma (PA) with which it was previously classified.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Cerebrospinal Fluid Rhinorrhea / etiology
  • [MeSH-minor] Adolescent. Humans. Intracranial Hypertension / etiology. Male

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  • (PMID = 19718549.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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30. Miura FK, Alves MJ, Rocha MC, da Silva R, Oba-Shinjo SM, Marie SK: Xenograft transplantation of human malignant astrocytoma cells into immunodeficient rats: an experimental model of glioblastoma. Clinics (Sao Paulo); 2010 Mar;65(3):305-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Xenograft transplantation of human malignant astrocytoma cells into immunodeficient rats: an experimental model of glioblastoma.
  • INTRODUCTION: Astrocytic gliomas are the most common intracranial central nervous system neoplasias, accounting for about 60% of all primary central nervous system tumors.
  • OBJECTIVE: To develop an experimental malignant astrocytoma model with the characteristics of the human tumor.
  • METHOD: Primary cells from subcutaneous xenograft tumors produced with malignant astrocytoma U87MG cells were inoculated intracerebrally by stereotaxis into immunosuppressed (athymic) Rowett rats.
  • CONCLUSION: A malignant astrocytoma intracerebral xenograft model with poorly invasive behavior was achieved in athymic Rowett rats.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Glioblastoma / pathology. Immunocompromised Host

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  • [Cites] Anticancer Res. 2006 Jul-Aug;26(4B):2887-900 [16886610.001]
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  • (PMID = 20360922.001).
  • [ISSN] 1980-5322
  • [Journal-full-title] Clinics (São Paulo, Brazil)
  • [ISO-abbreviation] Clinics (Sao Paulo)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Other-IDs] NLM/ PMC2845772
  • [Keywords] NOTNLM ; Athymic Rowett rats / Brain tumor / Experimental model / U87MG cells
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31. Mallur PS, Wisoff JH, Lalwani AK: Steroid responsive fluctuating sensorineural hearing loss due to juvenile pilocytic astrocytoma involving the cerebellopontine angle. Int J Pediatr Otorhinolaryngol; 2008 Apr;72(4):529-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Steroid responsive fluctuating sensorineural hearing loss due to juvenile pilocytic astrocytoma involving the cerebellopontine angle.
  • Tumors of the cerebellopontine angle (CPA) are common and represent up to 10% of all intracranial tumors.
  • The patient underwent gross total resection of the juvenile pilocytic astrocytoma via retrosigmoid craniotomy and remains disease free at 2 years postoperatively.
  • [MeSH-major] Anti-Inflammatory Agents / therapeutic use. Astrocytoma / complications. Astrocytoma / pathology. Brain Neoplasms / complications. Brain Neoplasms / pathology. Cerebellopontine Angle / pathology. Hearing Loss, Sensorineural / drug therapy. Hearing Loss, Sensorineural / etiology


32. Maeda M, Namikawa K, Kobayashi I, Ohba N, Takahara Y, Kadono C, Tanaka A, Kiyama H: Targeted gene therapy toward astrocytoma using a Cre/loxP-based adenovirus system. Brain Res; 2006 Apr 7;1081(1):34-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Targeted gene therapy toward astrocytoma using a Cre/loxP-based adenovirus system.
  • The aim of this study was to establish a novel adenovirus-based gene therapy system targeting astrocytoma.
  • For this purpose, the Cre recombinase (Cre)/loxP system together with the astrocytoma-specific promoter for GFAP were used.
  • Furthermore, a combination of AxGFAPNCre/AxCALGLTK and intraperitoneal GCV injection significantly regressed intracranial C6 gliomas in the rat striatum and prolonged the survival time compared with control rats.
  • The present results indicate that this cell-type-specific gene therapy using a Cre/loxP adenovirus system is both operational and effective, at least against astrocytoma.
  • [MeSH-major] Astrocytoma / therapy. Extracellular Matrix Proteins / therapeutic use. Genetic Therapy. Integrases / therapeutic use. Protein-Lysine 6-Oxidase / therapeutic use. Viral Proteins / therapeutic use

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  • (PMID = 16529724.001).
  • [ISSN] 0006-8993
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Extracellular Matrix Proteins; 0 / Viral Proteins; 149137-54-2 / Lox protein, mouse; EC 1.4.3.13 / Protein-Lysine 6-Oxidase; EC 2.7.7.- / Cre recombinase; EC 2.7.7.- / Integrases
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33. Klein O, Grignon Y, Civit T, Pinelli C, Auque J, Marchal JC: [Childhood diencephalic pilocytic astrocytoma. A review of seven observations]. Neurochirurgie; 2006 Feb;52(1):3-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Childhood diencephalic pilocytic astrocytoma. A review of seven observations].
  • BACKGROUND AND PURPOSE: Pilocytic astrocytoma (PA) is a WHO grade I tumor of the central nervous system mostly arising in children and young adults.
  • At the onset, the first symptom was mostly raised intracranial pressure.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Hypothalamic Neoplasms / surgery. Thalamic Diseases / surgery

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  • (PMID = 16609655.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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34. Vancura RW, Kepes JJ, Newell KL, Ha TM, Arnold PM: Secondary intracranial neoplasms exhibiting features of astrocytoma and neuroblastoma in 2 children treated for acute lymphoblastic leukemia: report of 2 cases. Surg Neurol; 2006 May;65(5):490-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secondary intracranial neoplasms exhibiting features of astrocytoma and neuroblastoma in 2 children treated for acute lymphoblastic leukemia: report of 2 cases.
  • We report 2 patients who were diagnosed with pre-B-cell acute lymphoblastic leukemia and later presented with intracranial malignancies.
  • [MeSH-major] Astrocytoma. Brain Neoplasms / secondary. Brain Neoplasms / therapy. Neoplasms, Second Primary. Neuroblastoma. Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy


35. Martínez-Murillo R, Martínez A: Standardization of an orthotopic mouse brain tumor model following transplantation of CT-2A astrocytoma cells. Histol Histopathol; 2007 12;22(12):1309-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Standardization of an orthotopic mouse brain tumor model following transplantation of CT-2A astrocytoma cells.
  • With the aim to develop and characterize a suitable in vivo experimental mouse model for infiltrating astrocytoma, with predictable and reproducible growth patterns that recapitulate human astrocytoma, this study was undertaken to analyze the long-term course of a syngeneic orthotopically implanted CT-2A mouse astrocytoma in C57BL/6J mice.
  • Intracranial injection of CT-2A cells into caudate-putamen resulted in development of an aggressive tumor showing typical features of human glioblastoma multiforme, sharing close histological, immunohistochemical, proliferative, and metabolic profiles.
  • Tumors identical to those obtained by intracranial injection were obtained.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / diagnosis. Brain Neoplasms / pathology. Disease Models, Animal

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  • (PMID = 17701911.001).
  • [ISSN] 1699-5848
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors
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36. Romeike BF, Böckeler A, Kremmer E, Sommer P, Krick C, Grässer F: Immunohistochemical detection of dUTPase in intracranial tumors. Pathol Res Pract; 2005;201(11):727-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical detection of dUTPase in intracranial tumors.
  • A hundred and twenty-seven human intracranial tumors, including 56 astrocytomas, 12 oligodendrogliomas, 8 oligoastrocytomas, 34 meningiomas, 7 ependymomas, and 10 metastatic carcinomas, were stained using the monoclonal rat anti-human dUTPase antibody (clone 3E6) with formalin-fixed and paraffin-embedded tissue.
  • Labeling indices for dUTPase, but not for Ki-67, showed significant differences between all 3 WHO grades of diffuse astrocytomas.
  • It proved particularly useful for the evaluation of diffuse astrocytomas.
  • [MeSH-minor] Astrocytoma / enzymology. Astrocytoma / immunology. Astrocytoma / pathology. Cell Nucleus / enzymology. Cell Nucleus / immunology. Cell Proliferation. Ependymoma / enzymology. Ependymoma / immunology. Ependymoma / pathology. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Meningioma / enzymology. Meningioma / immunology. Meningioma / pathology. Oligodendroglioma / enzymology. Oligodendroglioma / immunology. Oligodendroglioma / pathology. Paraffin Embedding. World Health Organization

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  • [ErratumIn] Pathol Res Pract. 2006;202(1):65
  • (PMID = 16325515.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; EC 3.6.1.- / Pyrophosphatases; EC 3.6.1.23 / dUTP pyrophosphatase
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37. Fenton E, Refai D, See W, Rawluk DJ: Supratentorial juvenile pilocytic astrocytoma in a young adult with Silver-Russell syndrome. Br J Neurosurg; 2008 Dec;22(6):776-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Supratentorial juvenile pilocytic astrocytoma in a young adult with Silver-Russell syndrome.
  • An association with malignancy exists and only one previous intracranial tumour has been reported, a craniopharyngioma.
  • We report the first case of Silver-Russell syndrome associated with a supratentorial juvenile pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / complications. Chromosome Disorders / complications. Fetal Growth Retardation. Headache Disorders / etiology


38. Kida Y, Yoshimoto M, Hasegawa T: Radiosurgery for intracranial gliomas. Prog Neurol Surg; 2009;22:122-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiosurgery for intracranial gliomas.
  • Long-term results of radiosurgery for GI to GIV astrocytomas are described.
  • We have treated 172 astrocytoma cases in total, including 25 GI cases, 52 GII cases, 41 GIII cases and 54 GIV astrocytoma cases.
  • The maximum and marginal doses for GI astrocytomas were significantly lower than those for the other three grades due to their proximity to the optic nerves.
  • However, the response rates of GIII and GIV astrocytomas were very low.
  • [MeSH-major] Astrocytoma / mortality. Astrocytoma / surgery. Brain Neoplasms / mortality. Brain Neoplasms / surgery. Radiosurgery

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  • (PMID = 18948724.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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39. Snyder JM, Shofer FS, Van Winkle TJ, Massicotte C: Canine intracranial primary neoplasia: 173 cases (1986-2003). J Vet Intern Med; 2006 May-Jun;20(3):669-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Canine intracranial primary neoplasia: 173 cases (1986-2003).
  • Of the 173 primary brain tumors, 78 (45%) were meningiomas, 29 (17%) were astrocytomas, 25 (14%) were oligodendrogliomas, 12 (7%) were choroid plexus tumors, and 7 (4%) were primary central nervous system lymphomas.
  • One dog had both a meningioma and an astrocytoma.
  • Based on the results of this study, thoracic radiographs and abdominal ultrasonography may be indicated to look for extracranial neoplasia prior to advanced imaging of the brain or intracranial surgery.

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  • (PMID = 16734106.001).
  • [ISSN] 0891-6640
  • [Journal-full-title] Journal of veterinary internal medicine
  • [ISO-abbreviation] J. Vet. Intern. Med.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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40. Abel TJ, Chowdhary A, Thapa M, Rutledge JC, Geyer JR, Ojemann J, Avellino AM: Spinal cord pilocytic astrocytoma with leptomeningeal dissemination to the brain. Case report and review of the literature. J Neurosurg; 2006 Dec;105(6 Suppl):508-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal cord pilocytic astrocytoma with leptomeningeal dissemination to the brain. Case report and review of the literature.
  • The authors report a unique case of leptomeningeal dissemination of a spinal cord pilocytic astrocytoma (PCA) to the intracranial cerebral subarachnoid spaces in a child.
  • Postoperative imaging after his last surgery revealed diffuse intracranial leptomeningeal dissemination into the cisternal space surrounding the midbrain, the suprasellar region, and the internal auditory canal, as well as nodular subarachnoid disease in the upper cervical region.
  • [MeSH-major] Astrocytoma / secondary. Brain Neoplasms / secondary. Meningeal Neoplasms / secondary. Spinal Cord Neoplasms / pathology


41. Guo XL, Zhong YF, Sun YH, Liu HH, Jin B, Liang W, Li XS: [Muscle atrophy of hand as an initial sign in a patient with protoplasmic astrocytoma: a case report and literature review]. Beijing Da Xue Xue Bao; 2008 Dec 18;40(6):649-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Muscle atrophy of hand as an initial sign in a patient with protoplasmic astrocytoma: a case report and literature review].
  • We reported a rare case of protoplasmic astrocytoma presenting small muscle atrophy of the right hand as an initial sign.
  • CT and MRI revealed multiply expansive intracranial lesion in left hemisphere, which was highly suspected of cerebral echinococcus or Balo disease.
  • The patient underwent surgical excision and pathological report was protoplasmic astrocytoma, with glial fibrillary acidic protein (GFAP, +++) of immunohistochemical method.
  • We reviewed clinical features, radiological manifestations and pathology of protoplasmic astrocytoma with medical literature documents.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Muscular Atrophy / complications

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  • (PMID = 19088841.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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42. Jang FF, Wei W, De WM: Vascular endothelial growth factor and basic fibroblast growth factor expression positively correlates with angiogenesis and peritumoural brain oedema in astrocytoma. J Ayub Med Coll Abbottabad; 2008 Apr-Jun;20(2):105-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vascular endothelial growth factor and basic fibroblast growth factor expression positively correlates with angiogenesis and peritumoural brain oedema in astrocytoma.
  • BACKGROUND: Astrocytoma is the most malignant intracranial neoplasm and is characterized by high neovascularization and peritumoural brain oedema.
  • METHODS: The expression of two angiogenic growth factors, vascular endothelial growth factor and basic fibroblast growth factor were investigated using immunohistochemistry for astrocytoma from 82 patients and 11 normal human tissues.
  • RESULTS: The expression of vascular endothelial growth factor and basic fibroblast growth factor positively correlate with the pathological grade of astrocytoma, microvessel density numbers and brain oedema, which may be responsible for the increased tumour neovascularization and peritumoural brain oedema.
  • CONCLUSION: The results support the idea that inhibiting vascular endothelial growth factor and basic fibroblast growth factor are useful for the treatment of human astrocytoma and to improve patient's clinical outcomes and prognosis.
  • [MeSH-major] Astrocytoma / blood supply. Brain Edema / etiology. Brain Neoplasms / blood supply. Fibroblast Growth Factor 2 / biosynthesis. Neovascularization, Pathologic / metabolism. Vascular Endothelial Growth Factor A / biosynthesis

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  • (PMID = 19385471.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A; 103107-01-3 / Fibroblast Growth Factor 2
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43. Hon SF, Wong GK, Zhu XL, Ng HK, Sin NC, Poon WS: Surgical treatment of a neonate with refractory seizures secondary to congenital giant cell astrocytoma: case report and literature review. Hong Kong Med J; 2006 Jun;12(3):222-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of a neonate with refractory seizures secondary to congenital giant cell astrocytoma: case report and literature review.
  • They account for 0.5% to 1.9% of intracranial tumours in childhood and have an incidence of 0.34 per million live births.
  • Most congenital brain tumours are neuro-ectodermal tumours and medulloblastomas; giant cell astrocytoma and other tuberous sclerosis-related tumours are rare.
  • Surgical resection was performed successfully and pathology revealed the tumour to be a giant cell astrocytoma.

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  • (PMID = 16760552.001).
  • [ISSN] 1024-2708
  • [Journal-full-title] Hong Kong medical journal = Xianggang yi xue za zhi
  • [ISO-abbreviation] Hong Kong Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Anticonvulsants
  • [Number-of-references] 8
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44. Salunke P, Badhe P, Sharma A: Cerebellar glioblastoma multiforme with non-contiguous grade 2 astrocytoma of the temporal lobe in the same individual. Neurol India; 2010 Jul-Aug;58(4):651-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar glioblastoma multiforme with non-contiguous grade 2 astrocytoma of the temporal lobe in the same individual.
  • We report a unique occurrence of such a combination in a 50-year-old man who presented with features of elevated intracranial pressure, ataxia and vertigo.
  • Histopathology revealed grade II astrocytoma in the temporal lobe and glioblastoma multiforme in the cerebellum.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Glioblastoma / complications. Temporal Lobe / pathology

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  • (PMID = 20739816.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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45. Distelmaier F, Janssen G, Mayatepek E, Schaper J, Göbel U, Rosenbaum T: Disseminated pilocytic astrocytoma involving brain stem and diencephalon: a history of atypical eating disorder and diagnostic delay. J Neurooncol; 2006 Sep;79(2):197-201
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Disseminated pilocytic astrocytoma involving brain stem and diencephalon: a history of atypical eating disorder and diagnostic delay.
  • In this report we present an unusual case of severe emaciation in a 4(9)/(12)-year-old girl with a juvenile pilocytic astrocytoma of the hypothalamic region and brain stem with neuroaxis dissemination.
  • This case illustrates the importance of considering intracranial mass-lesions in the differential diagnosis of weight loss, psychological disturbance and atypical eating disorder.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Emaciation / etiology. Feeding and Eating Disorders / etiology

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  • (PMID = 16598421.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Ulu MO, Tanriöver N, Biçeroğlu H, Oz B, Canbaz B: A case report: a noninfantile desmoplastic astrocytoma. Turk Neurosurg; 2008 Jan;18(1):42-6
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  • [Title] A case report: a noninfantile desmoplastic astrocytoma.
  • INTRODUCTION AND CASE DESCRIPTION: Desmoplastic infantile astrocytomas (DIA) are rare intracranial tumors of infancy with distinctive clinical and radiological features.
  • Careful diagnosis and differentiation of DIA cases with other tumors, particularly malignant astrocytomas is important since the therapeutic strategies may differ.
  • [MeSH-major] Astrocytoma / pathology. Astrocytoma / surgery. Brain Neoplasms / pathology. Brain Neoplasms / surgery. Magnetic Resonance Imaging

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  • (PMID = 18382977.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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47. White JB, Piepgras DG, Scheithauer BW, Parisi JE: Rate of spontaneous hemorrhage in histologically proven cases of pilocytic astrocytoma. J Neurosurg; 2008 Feb;108(2):223-6
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  • [Title] Rate of spontaneous hemorrhage in histologically proven cases of pilocytic astrocytoma.
  • The rate of tumor-related intracranial hemorrhage is variably reported from <1 to 14.6%.
  • Hemorrhage in primary gliomas occurs in 3.7-7.2% of gliomas, mainly in glioblastoma muliforme and oligodendroglioma with low-grade astrocytomas accounting for <1%.
  • Hemorrhage associated with pilocytic astrocytomas (PAs) is only sporadically reported.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Cerebral Hemorrhage / etiology


48. Yoshikawa G, Kawamoto S, Yakou K, Tsutsumi K: Massive intracranial hemorrhage associated with pleomorphic xanthoastrocytoma--case report. Neurol Med Chir (Tokyo); 2010;50(3):220-3
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  • [Title] Massive intracranial hemorrhage associated with pleomorphic xanthoastrocytoma--case report.
  • A 60-year-old woman with a history of intermittent headaches and frequent seizures for 30 years presented with a massive intracranial hematoma in the left medial temporal lobe with thick subarachnoid hemorrhage.
  • [MeSH-major] Aneurysm, False / etiology. Aneurysm, Ruptured / etiology. Astrocytoma / complications. Brain Neoplasms / complications. Hematoma, Subdural, Intracranial / etiology. Subarachnoid Hemorrhage / etiology

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  • (PMID = 20339272.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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49. Zengin E, Atukeren P, Kokoglu E, Gumustas MK, Zengin U: Alterations in lipid peroxidation and antioxidant status in different types of intracranial tumors within their relative peritumoral tissues. Clin Neurol Neurosurg; 2009 May;111(4):345-51
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  • [Title] Alterations in lipid peroxidation and antioxidant status in different types of intracranial tumors within their relative peritumoral tissues.
  • OBJECTIVES: Elevated levels of lipid peroxidation and changes in the concentration of enzymatic and non-enzymatic antioxidant systems have been reported in various cancers, but there are very few reports available of lipid peroxidation due to oxidative stress in patients with intracranial neoplasms.
  • PATIENTS AND METHODS: We investigated the extent of oxidative stress and the levels of antioxidants in 16 astrocytomas and 38 other different types intracranial tumors comparing the results with their corresponding peritumoral tissues and comparing the levels in between low-grade and high-grade tumors.
  • [MeSH-major] Antioxidants / metabolism. Astrocytoma / metabolism. Astrocytoma / pathology. Brain Neoplasms / metabolism. Brain Neoplasms / pathology. Lipid Peroxidation. Oxidative Stress

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  • (PMID = 19117666.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Thiobarbituric Acid Reactive Substances; EC 1.15.1.1 / Superoxide Dismutase; EC 1.8.1.7 / Glutathione Reductase; GAN16C9B8O / Glutathione
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50. Madhankumar AB, Slagle-Webb B, Wang X, Yang QX, Antonetti DA, Miller PA, Sheehan JM, Connor JR: Efficacy of interleukin-13 receptor-targeted liposomal doxorubicin in the intracranial brain tumor model. Mol Cancer Ther; 2009 Mar;8(3):648-54
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  • [Title] Efficacy of interleukin-13 receptor-targeted liposomal doxorubicin in the intracranial brain tumor model.
  • Based on this observation, we developed an intracranial brain tumor model in nude mice using human U87 glioma cells.
  • Mice receiving weekly i.p. injections of 15 mg/kg of doxorubicin encapsulated in IL-13-conjugated liposomes had a 5-fold reduction in the intracranial tumor volume over 6 weeks and four of seven animals survived >200 days after tumor implantation.
  • Finally, a model of the blood-brain barrier was used to show that the nanovesicles do not harm the endothelial cells yet maintain their toxicity to astrocytoma cells.
  • [MeSH-major] Astrocytoma / drug therapy. Brain Neoplasms / drug therapy. Doxorubicin / administration & dosage. Receptors, Interleukin-13 / antagonists & inhibitors

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  • (PMID = 19276162.001).
  • [ISSN] 1535-7163
  • [Journal-full-title] Molecular cancer therapeutics
  • [ISO-abbreviation] Mol. Cancer Ther.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Liposomes; 0 / Receptors, Interleukin-13; 80168379AG / Doxorubicin
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51. Uesaka T, Shono T, Suzuki SO, Nakamizo A, Niiro H, Mizoguchi M, Iwaki T, Sasaki T: Expression of VEGF and its receptor genes in intracranial schwannomas. J Neurooncol; 2007 Jul;83(3):259-66
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  • [Title] Expression of VEGF and its receptor genes in intracranial schwannomas.
  • In this study, we determined the expression levels of VEGF, and vascular endothelial growth factor receptor (VEGFR)-1 and -2 mRNA in 46 intracranial schwannomas by quantitative real-time PCR, and correlated these with various clinical factors or other molecular markers.
  • Based on these observations, the significance of VEGF and its receptor genes in intracranial schwannomas is discussed.
  • [MeSH-minor] Adult. Aged. Antigens, Neoplasm / metabolism. Astrocytoma / genetics. Astrocytoma / metabolism. Astrocytoma / pathology. Cranial Nerve Neoplasms / genetics. Cranial Nerve Neoplasms / metabolism. Cranial Nerve Neoplasms / pathology. DNA Topoisomerases, Type II / metabolism. DNA-Binding Proteins / metabolism. Female. Glioblastoma / genetics. Glioblastoma / metabolism. Glioblastoma / pathology. Humans. Immunoenzyme Techniques. Male. Meningioma / genetics. Meningioma / metabolism. Meningioma / pathology. Middle Aged. Neoplasm Recurrence, Local / genetics. Neoplasm Recurrence, Local / metabolism. Neoplasm Recurrence, Local / pathology. Neurofibromin 2 / genetics. RNA, Messenger / metabolism. RNA, Neoplasm / genetics. RNA, Neoplasm / metabolism. Reverse Transcriptase Polymerase Chain Reaction / methods. Ubiquitin-Protein Ligases / metabolism

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  • (PMID = 17570036.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Vougiouklakis T, Mitselou A, Agnantis NJ: Sudden death due to primary intracranial neoplasms. A forensic autopsy study. Anticancer Res; 2006 May-Jun;26(3B):2463-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sudden death due to primary intracranial neoplasms. A forensic autopsy study.
  • A search for cases of sudden death due to intracranial tumors from a total of 1985 autopsies from the archives of the Department of Forensic Pathology, University of Ioannina, Greece, in the period 1998-2005, was undertaken.
  • A 4-cm astrocytoma of the left temporal lobe had been found at autopsy.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Glioblastoma / pathology

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  • (PMID = 16821633.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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53. Makino K, Nakamura H, Yano S, Kuratsu J, Kumamoto Brain Tumor Group: Population-based epidemiological study of primary intracranial tumors in childhood. Childs Nerv Syst; 2010 Aug;26(8):1029-34
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  • [Title] Population-based epidemiological study of primary intracranial tumors in childhood.
  • The aim of this study was to determine the epidemiology of childhood primary intracranial tumors in Kumamoto Prefecture, Japan.
  • METHODS: We surveyed 210 patients younger than 15 years who were diagnosed with primary intracranial tumors between 1989 and 2008; 159 (75.7%) of the tumors were confirmed microscopically.
  • The most common tumor was astrocytoma (35.7%) with an annual incidence rate of 13.2 per million, followed by germ cell tumor (14.3%, 5.0 per million), craniopharyngioma (10.5%, 3.8 per million), medulloblastoma (10.0%, 3.7 per million), and ependymoma (4.8%, 1.5 per million).
  • CONCLUSIONS: In this Kumamoto survey, the incidence rate of primary intracranial tumors in children was similar to that in Western countries.

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  • (PMID = 20349186.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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54. Mehrazin M, Yavari P: Morphological pattern and frequency of intracranial tumors in children. Childs Nerv Syst; 2007 Feb;23(2):157-62
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  • [Title] Morphological pattern and frequency of intracranial tumors in children.
  • OBJECTIVE: To determine the age, sex, location, and histologic diagnosis of intracranial tumors in children less than 15 years of age.
  • The mixed five most common histological diagnoses in patients were astrocytoma (40.4%), followed by medulloblastoma (18.4%), ependymoma (10.5%), craniopharyngioma (8.8%), and meningioma (4.2%).
  • Astrocytoma occurred mostly in children aged 5-15 years (87%).
  • Astrocytoma was the first most common brain tumor in all age groups.

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  • (PMID = 16953459.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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55. Boss A, Bisdas S, Kolb A, Hofmann M, Ernemann U, Claussen CD, Pfannenberg C, Pichler BJ, Reimold M, Stegger L: Hybrid PET/MRI of intracranial masses: initial experiences and comparison to PET/CT. J Nucl Med; 2010 Aug;51(8):1198-205
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  • [Title] Hybrid PET/MRI of intracranial masses: initial experiences and comparison to PET/CT.
  • In a pilot study of 10 patients with intracranial masses, the feasibility of tumor assessment using a PET/MRI system comprising lutetium oxyorthosilicate scintillators coupled to avalanche photodiodes was evaluated, and quantification accuracy was compared with conventional PET/CT datasets.
  • Diagnoses at the time of referral were low-grade astrocytoma (n = 2), suspicion of low-grade astrocytoma (n = 1), anaplastic astrocytoma (World Health Organization grade III; n = 1), glioblastoma (n = 2), atypical neurocytoma (n = 1), and meningioma (n = 3).

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  • (PMID = 20660388.001).
  • [ISSN] 1535-5667
  • [Journal-full-title] Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • [ISO-abbreviation] J. Nucl. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gallium Radioisotopes; 0 / Radiopharmaceuticals; AE28F7PNPL / Methionine; RWM8CCW8GP / Octreotide; U194AS08HZ / Edotreotide
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56. Daglioglu E, Ergungor F, Hatipoglu HG, Okay O, Dalgic A, Orhan G, Unal T: Cerebral leukoencephalopathy with calcifications and cysts operated for signs of increased intracranial pressure: case report. Surg Neurol; 2009 Aug;72(2):177-81
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  • [Title] Cerebral leukoencephalopathy with calcifications and cysts operated for signs of increased intracranial pressure: case report.
  • It should be differentiated from FD or bilateral striopallidodentate calcinosis and astrocytoma.
  • CONCLUSION: Patients with findings of cystic cerebral calcifications on CT scans should be followed cautiously for acute deterioration because surgery is indicated in cases having signs of increased intracranial pressure.
  • [MeSH-major] Calcinosis / diagnosis. Central Nervous System Cysts / diagnosis. Cerebellar Diseases / complications. Cerebellar Diseases / diagnosis. Cerebellum / pathology. Intracranial Hypertension / etiology. Intracranial Hypertension / surgery

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  • (PMID = 18514290.001).
  • [ISSN] 1879-3339
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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57. Nagatani M, Yamakawa S, Ando R, Edamoto H, Saito T, Tamura K: Highly invasive intracranial malignant schwannoma in a rat. J Toxicol Pathol; 2009 Jun;22(2):139-42

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  • [Title] Highly invasive intracranial malignant schwannoma in a rat.
  • A highly invasive intracranial malignant schwannoma containing several masses was detected in a 28-week-old male Crl:CD(SD) rat.
  • In the brain, the tumor cells infiltrated diffusely into the leptomeningeal and perivascular spaces and parenchyma, in which the tumor cell morphology and invasive pattern closely resembled those of malignant astrocytoma and malignant reticulosis.

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  • (PMID = 22271987.001).
  • [ISSN] 0914-9198
  • [Journal-full-title] Journal of toxicologic pathology
  • [ISO-abbreviation] J Toxicol Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Other-IDs] NLM/ PMC3246059
  • [Keywords] NOTNLM ; cranial cavity / malignant schwannoma / rat / spontaneous
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58. Rogne SG, Konglund A, Meling TR, Scheie D, Johannesen TB, Rønning P, Helseth E: Intracranial tumor surgery in patients &gt;70 years of age: is clinical practice worthwhile or futile? Acta Neurol Scand; 2009 Nov;120(5):288-94
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  • [Title] Intracranial tumor surgery in patients >70 years of age: is clinical practice worthwhile or futile?
  • OBJECTIVES: To study survival and functional outcome after intracranial tumor surgery in elderly patients.
  • MATERIALS AND METHODS: This is a retrospective study of 289 consecutive patients of age > or =70 years, who underwent primary surgery (resection or biopsy) in the time period 2003-2007 for an intracranial tumor (87 astrocytomas, 79 meningiomas, 62 brain metastases, 33 pituitary adenomas and 28 other tumors).
  • One-year survival after surgery for astrocytoma, meningioma, brain metastases and pituitary adenoma were 24%, 94%, 31% and 96% respectively.
  • CONCLUSIONS: Surgery for intracranial tumors in selected elderly patients is worthwhile, not futile.

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  • [ErratumIn] Acta Neurol Scand. 2009 Dec;120(6):453
  • (PMID = 19737154.001).
  • [ISSN] 1600-0404
  • [Journal-full-title] Acta neurologica Scandinavica
  • [ISO-abbreviation] Acta Neurol. Scand.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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59. Polin RS, Marko NF, Ammerman MD, Shaffrey ME, Huang W, Anderson FA Jr, Caputy AJ, Laws ER: Functional outcomes and survival in patients with high-grade gliomas in dominant and nondominant hemispheres. J Neurosurg; 2005 Feb;102(2):276-83
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  • OBJECT: The goal of this study was to investigate survival and functional outcomes in patients with high-grade intracranial astrocytomas as a function of the location of the lesion in the dominant or nondominant hemisphere (DH and NDH, respectively), and to suggest management strategies for such patients based on these data.
  • METHODS: Data were collected from the Glioma Outcomes Project database, a longitudinal database of demographic, clinical, and outcome data for patients with high-grade intracranial gliomas.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Glioblastoma / surgery. Karnofsky Performance Status. Postoperative Complications / diagnosis

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  • (PMID = 15739555.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] United States
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60. El-Gaidi MA, Eissa EM: Infantile intracranial neoplasms: characteristics and surgical outcomes of a contemporary series of 21 cases in an Egyptian referral center. Pediatr Neurosurg; 2010;46(4):272-82
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  • [Title] Infantile intracranial neoplasms: characteristics and surgical outcomes of a contemporary series of 21 cases in an Egyptian referral center.
  • OBJECTIVE: To investigate the demographic, clinical, radiological, pathological and surgical features and outcomes of infantile intracranial neoplasms, the second most common neoplasm in infants.
  • RESULTS: Out of 451 patients with primary intracranial neoplasms (age 0-14 years), 21 infants (<1 year) underwent surgery, representing 4.7% of total cases.
  • The most common tumor was choroid plexus papilloma (23.8%), followed by teratoma (19%) then astrocytoma and ependymoma (14.3% each).
  • CONCLUSION: Although the prognosis for infantile intracranial neoplasms is worse than for older children, an overall promising outcome with low operative morbidity and mortality was achieved using gross total excision and appropriate adjuvant chemotherapy as part of a multidisciplinary approach.
  • [MeSH-minor] Adolescent. Astrocytoma / drug therapy. Astrocytoma / mortality. Astrocytoma / surgery. Chemotherapy, Adjuvant. Child. Child, Preschool. Combined Modality Therapy. Egypt / epidemiology. Ependymoma / drug therapy. Ependymoma / mortality. Ependymoma / surgery. Female. Humans. Infant. Infant, Newborn. Male. Medulloblastoma / drug therapy. Medulloblastoma / mortality. Medulloblastoma / surgery. Morbidity. Neurilemmoma / drug therapy. Neurilemmoma / mortality. Neurilemmoma / surgery. Prognosis. Quality of Life. Referral and Consultation / statistics & numerical data. Retrospective Studies. Teratoma / drug therapy. Teratoma / mortality. Teratoma / surgery

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  • [Copyright] Copyright © 2010 S. Karger AG, Basel.
  • (PMID = 21160236.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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61. Müller-Forell W: [Neuroradiology of the intracranial visual pathway. Part II]. Radiologe; 2005 Nov;45(11):1043-55
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  • [Title] [Neuroradiology of the intracranial visual pathway. Part II].
  • Part 2 mainly presents intrinsic lesions as the most common brain tumors (astrocytoma of all grades, ependymoma), arising in the region of the visual pathway.
  • [MeSH-minor] Adult. Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Child. Ependymoma / diagnosis. Female. Hemangioma, Cavernous / diagnosis. Humans. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Middle Aged. Multiple Sclerosis / diagnosis. Sarcoidosis / diagnosis. Sturge-Weber Syndrome / diagnosis

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  • [Cites] Eur J Radiol. 2004 Feb;49(2):143-78 [14746935.001]
  • [Cites] Kidney Blood Press Res. 2004;27(4):226-38 [15273425.001]
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  • [Cites] Radiologe. 2000 Nov;40(11):1090-7 [11147324.001]
  • (PMID = 16228165.001).
  • [ISSN] 0033-832X
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 17
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62. Bahloul K, Ouerchefani N, Kammoun B, Boudouara MZ: Unusual brain edema caused by an intracranial hydatid cyst: c ase report and literature review. Neurochirurgie; 2009 Feb;55(1):53-6
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  • [Title] Unusual brain edema caused by an intracranial hydatid cyst: c ase report and literature review.
  • The differential diagnosis of intracranial brain cystic lesions, including malignant lesions, abscesses and cystic astrocytoma, can sometimes be difficult even when using a sophisticated imaging technique.
  • A case of a six-year-old male with raised intracranial tension and rapid consciousness disturbance presumably caused by a left frontal hydatid cyst, surrounded by an unusual edema is reported.
  • We concluded that intracranial hydatid cyst should be entertained whenever a cystic lesion is found in an endemic region.

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  • (PMID = 18586282.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Anthelmintics; F4216019LN / Albendazole
  • [Number-of-references] 13
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63. Moenninghoff C, Maderwald S, Theysohn JM, Kraff O, Ladd ME, El Hindy N, van de Nes J, Forsting M, Wanke I: Imaging of adult astrocytic brain tumours with 7 T MRI: preliminary results. Eur Radiol; 2010 Mar;20(3):704-13
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  • PURPOSE: In this study tumour vascularity and necrosis of intracranial astrocytomas were compared using 7 T and 1.5 T magnetic resonance imaging (MRI).
  • METHODS: Fifteen patients with histologically proven astrocytomas (WHO grades II-IV) were prospectively examined at 1.5 T (Magnetom Espree or Sonata) and 7 T (Magnetom 7 T, Siemens, Erlangen, Germany) with T2*-w (weighted), T1-w with (only a subset of five patients at 7 T) and without contrast medium, T2-w and proton-density (PD)-w MRI.
  • Two diffusely infiltrating astrocytomas, four anaplastic astrocytomas and nine glioblastomas were included.
  • CONCLUSION: 7 T gradient-echo sequences provide excellent image contrast of presumed microvasculature and necrosis in astrocytomas.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Magnetic Resonance Imaging / methods. Neovascularization, Pathologic / pathology

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  • [Cites] J Neuropathol Exp Neurol. 2002 Mar;61(3):215-25; discussion 226-9 [11895036.001]
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  • (PMID = 19763581.001).
  • [ISSN] 1432-1084
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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64. Rossmeisl JH, Duncan RB, Huckle WR, Troy GC: Expression of vascular endothelial growth factor in tumors and plasma from dogs with primary intracranial neoplasms. Am J Vet Res; 2007 Nov;68(11):1239-45
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of vascular endothelial growth factor in tumors and plasma from dogs with primary intracranial neoplasms.
  • OBJECTIVE: To quantitatively evaluate expression of vascular endothelial growth factor (VEGF) in intracranial tumors in dogs and determine whether relationships exist between circulating and intratumoral VEGF concentrations and tumor type and grade.
  • ANIMALS: 27 dogs with primary intracranial neoplasms and 4 unaffected control dogs.
  • RESULTS: Dogs with meningiomas (n = 11) were significantly older than dogs with oligodendrogliomas (7) or astrocytomas (9).
  • Age-adjusted comparisons identified significant differences in intratumoral VEGF concentrations among all tumor types; the highest VEGF concentrations were associated with astrocytomas.
  • Plasma VEGF concentrations were detectable in 9 of 27 dogs; the proportion of dogs with astrocytomas and a detectable circulating VEGF concentration (7/9 dogs) was significantly higher than the proportion of dogs with meningiomas (1/11 dogs) or oligodendrogliomas (1/7 dogs) with a detectable circulating VEGF concentration.
  • CONCLUSIONS AND CLINICAL RELEVANCE: Overexpression of VEGF appears common in canine astrocytomas, oligodendrogliomas, and meningiomas.
  • The VEGF expression patterns paralleled those of analogous human tumors, providing evidence that dogs are a suitable species in which to study angiogenesis and intracranial neoplasia for human application.
  • [MeSH-minor] Animals. Astrocytoma / metabolism. Astrocytoma / pathology. Astrocytoma / veterinary. Dogs. Enzyme-Linked Immunosorbent Assay / veterinary. Female. Histocytochemistry / veterinary. Male. Meningioma / metabolism. Meningioma / pathology. Meningioma / veterinary. Oligodendroglioma / metabolism. Oligodendroglioma / pathology. Oligodendroglioma / veterinary

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  • (PMID = 17975980.001).
  • [ISSN] 0002-9645
  • [Journal-full-title] American journal of veterinary research
  • [ISO-abbreviation] Am. J. Vet. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A
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65. Gupta B, Levchenko TS, Torchilin VP: TAT peptide-modified liposomes provide enhanced gene delivery to intracranial human brain tumor xenografts in nude mice. Oncol Res; 2007;16(8):351-9
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  • [Title] TAT peptide-modified liposomes provide enhanced gene delivery to intracranial human brain tumor xenografts in nude mice.
  • In this study, we have investigated the potential of trans-activating transcriptional activator peptide (TATp)-modified liposomes to enhance the delivery of the model gene, plasmid encoding for the green fluorescent protein (pEGFP-N1), to human brain tumor U-87 MG cells in vitro and in an intracranial model in nude mice.
  • In vivo transfection of intracranial brain tumors by intratumoral injections of TATp-lipoplexes showed an enhanced delivery of pEGFP-N1 selectively to tumor cells and subsequent effective transfection compared to plain plasmid-loaded lipoplexes.
  • [MeSH-major] Astrocytoma / therapy. Brain Neoplasms / therapy. DNA / administration & dosage. Gene Products, tat / administration & dosage. Genes, tat / genetics. Genetic Therapy / methods

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  • (PMID = 17913043.001).
  • [ISSN] 0965-0407
  • [Journal-full-title] Oncology research
  • [ISO-abbreviation] Oncol. Res.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL55519
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gene Products, tat; 0 / Liposomes; 147336-22-9 / Green Fluorescent Proteins; 9007-49-2 / DNA
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66. Pascual-Castroviejo I, Pascual-Pascual SI, Velázquez-Fragua R, Viaño J, Carceller F, Hernández-Moneo JL, Gutiérrez-Molina M, Morales C: [Subependymal giant cell astrocytoma in tuberous sclerosis complex. A presentation of eight paediatric patients]. Neurologia; 2010 Jun;25(5):314-21
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  • [Title] [Subependymal giant cell astrocytoma in tuberous sclerosis complex. A presentation of eight paediatric patients].
  • [Transliterated title] Astrocitoma subependimario de células gigantes en el complejo de esclerosis tuberosa. Presentación de ocho pacientes infantiles.
  • OBJECTIVE: Presentation of 8 patients with subependymal giant-cell astrocytomas (SGCA) associated with tuberous sclerosis complex (TSC).
  • Three of the patients were admitted urgently due to blindness and increased intracranial pressure.
  • [MeSH-major] Astrocytoma / etiology. Astrocytoma / pathology. Brain Neoplasms / etiology. Brain Neoplasms / pathology. Tuberous Sclerosis


67. Jaiswal S, Barai S, Rajkumar, Gambhir S, Ora M, Mahapatra AK: Evaluation of intracranial space-occupying lesion with Tc99m-glucoheptonate brain single photon emission computed tomography in treatment-naïve patients. J Postgrad Med; 2009 Jul-Sep;55(3):180-4
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  • [Title] Evaluation of intracranial space-occupying lesion with Tc99m-glucoheptonate brain single photon emission computed tomography in treatment-naïve patients.
  • Though extensively used as a tracer for detection of brain tumor recurrence, it's utility for characterization of intracranial lesions as neoplastic or otherwise has not been evaluated in treatment-naïve patients.
  • AIM: The study was conducted to determine if glucoheptonate has sufficient specificity for neoplastic lesions of brain so that it can be utilized as a single photon emission computed tomography (SPECT)-tracer for differentiating neoplastic intracranial lesions from non-neoplastic ones in treatment-naïve patients.
  • SETTINGS AND DESIGN: A cross-sectional analysis of treatment-naïve patients with intracranial space-occupying lesion done in a tertiary care hospital.
  • Histopathology of 12 out of the 13 glucoheptonate non-avid lesions turned out to be non-neoplastic lesion; however, one lesion was reported as a Grade-2 astrocytoma.
  • CONCLUSIONS: Glucoheptonate has high degree of specificity for neoplastic tissues of brain and may be used as a tracer for SPECT study to differentiate neoplastic intracranial lesions from non-neoplastic ones.

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  • [CommentIn] J Postgrad Med. 2010 Apr-Jun;56(2):168 [20622403.001]
  • [CommentIn] J Postgrad Med. 2009 Jul-Sep;55(3):159 [19884737.001]
  • (PMID = 19884742.001).
  • [ISSN] 0972-2823
  • [Journal-full-title] Journal of postgraduate medicine
  • [ISO-abbreviation] J Postgrad Med
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Organotechnetium Compounds; 0 / Radiopharmaceuticals; 0 / Sugar Acids; I853LE095B / technetium Tc 99m gluceptate
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68. Mehrazin M, Rahmat H, Yavari P: Epidemiology of primary intracranial tumors in Iran, 1978-2003. Asian Pac J Cancer Prev; 2006 Apr-Jun;7(2):283-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiology of primary intracranial tumors in Iran, 1978-2003.
  • The five most common histological types in both sexes were meningioma in 892 cases (26%) followed by astrocytoma in 805 cases (23.4%), pituitary adenoma in 488 cases (14.2%), glioblasomaoma in 278 cases (5.1%) and ependymoma in 166 cases (4.8%).
  • Male predominance was observed for the astrocytoma group, craniopharyngiomas, ependymomas, glioblastomas, medulloblastomas, and pituitary adenomas.

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  • (PMID = 16839224.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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69. Gupta B, Torchilin VP: Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice. Cancer Immunol Immunother; 2007 Aug;56(8):1215-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice.
  • Here, we investigate the therapeutic efficacy of monoclonal anticancer antibody 2C5-modified long-circulating liposomes (LCL) loaded with doxorubicin (2C5-DoxLCL) for the treatment of U-87 MG human brain tumors in an intracranial model in nude mice.
  • The treatment of intracranial U-87 MG brain tumors in nude mice with 2C5-DoxLCL provides a significant therapeutic benefit over control formulations, substantially reducing the tumor size and almost doubling the survival time.
  • Thus, monoclonal antibody 2C5-modified LCL can specifically target the anticancer drugs to brain tumors, leading to improved therapeutic treatment of brain tumor in an intracranial model, in vivo.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Antineoplastic Agents / therapeutic use. Astrocytoma / drug therapy. Brain Neoplasms / drug therapy. Doxorubicin / therapeutic use. Immunoconjugates / therapeutic use

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  • (PMID = 17219149.001).
  • [ISSN] 0340-7004
  • [Journal-full-title] Cancer immunology, immunotherapy : CII
  • [ISO-abbreviation] Cancer Immunol. Immunother.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL55519
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antineoplastic Agents; 0 / Immunoconjugates; 0 / Liposomes; 0 / Nucleosomes; 30IQX730WE / Polyethylene Glycols; 80168379AG / Doxorubicin
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70. Maes L, Van Neste L, Van Damme K, Kalala JP, De Ridder L, Bekaert S, Cornelissen M: Relation between telomerase activity, hTERT and telomere length for intracranial tumours. Oncol Rep; 2007 Dec;18(6):1571-6
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  • [Title] Relation between telomerase activity, hTERT and telomere length for intracranial tumours.
  • For gliomas, no active telomerase was detected in 2 low-grade astrocytomas, whereas three of the four screened glioblastomas were positive for telomerase activity.
  • The only hTERT protein positive astrocytoma had a mean labelling index of 9.0%.
  • The two low-grade astrocytomas had a telomere length of 14.310 and 9.236 kb.
  • The anaplastic astrocytoma had a telomere length of 4.903 kb and the glioblastomas 5.767 kb (SD=2.042).
  • [MeSH-minor] Astrocytoma / enzymology. Astrocytoma / genetics. Astrocytoma / pathology. Biopsy. Glioblastoma / enzymology. Glioblastoma / genetics. Glioblastoma / pathology. Humans

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  • (PMID = 17982646.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.7.7.49 / Telomerase
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71. French JL, McCullough J, Bachra P, Bedforth NM: Transversus abdominis plane block for analgesia after caesarean section in a patient with an intracranial lesion. Int J Obstet Anesth; 2009 Jan;18(1):52-4
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  • [Title] Transversus abdominis plane block for analgesia after caesarean section in a patient with an intracranial lesion.
  • General anaesthesia with supplementary bilateral ultrasound-guided transversus abdominis plane blocks was chosen to reduce the requirements for intra- and postoperative opioids, the risk of postoperative respiratory depression and the potential exacerbation of borderline raised intracranial pressure.
  • [MeSH-minor] Astrocytoma / complications. Astrocytoma / diagnosis. Brain Neoplasms / complications. Brain Neoplasms / diagnosis. Female. Humans. Magnetic Resonance Imaging. Pregnancy. Pregnancy Complications, Neoplastic / diagnosis. Ultrasonography, Interventional. Young Adult

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  • (PMID = 18996002.001).
  • [ISSN] 1532-3374
  • [Journal-full-title] International journal of obstetric anesthesia
  • [ISO-abbreviation] Int J Obstet Anesth
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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72. Tong Z, Wanibuchi M, Uede T, Tanabe S, Hashi K: Significant improvement of visual functions after removal of an intracranial giant optic nerve glioma revealing exophytic growth: case report. Neurosurgery; 2006 Apr;58(4):E792; discussion E792
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Significant improvement of visual functions after removal of an intracranial giant optic nerve glioma revealing exophytic growth: case report.
  • OBJECTIVE AND IMPORTANCE: Intracranial giant optic nerve gliomas, usually presumed as optic chiasmatic gliomas, are much less common.
  • Surgical decompression for intracranial optic gliomas frequently leads to clinical improvement, but obvious improvement of vision is rare.
  • We report a case that demonstrated significant recovery of visual function after removal of the intracranial giant optic nerve glioma, revealing exophytic growth.
  • On heavily T2-reversed MRIs, it was obvious that the intracranial portion of right optic nerve was enlarged, and optic tracts were shifted to the left by the tumor.
  • The histological diagnosis was pilocytic astrocytoma.
  • CONCLUSION: Giant exophytic gliomas without neurofibromatosis type 1 may arise from the intracranial portion of an isolated optic nerve.
  • Direct visualization of optic component by heavily T2-reversed MRI could more precisely delineate the relationship of the intracranial optic nerve glioma to the optic apparatus.
  • Surgery may be indicated in giant exophytic intracranial optic nerve gliomas and preoperative postulated optic chiasmatic gliomas.

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  • (PMID = 16575300.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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73. Mittal S, Oni-Orisan A, Stenz J, Shah AK: Temporal neocortical origin of pilomotor seizures in association with an infiltrating glioma: a case confirmed by intracranial electroencephalography monitoring. J Neurosurg; 2010 Aug;113(2):388-93
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  • [Title] Temporal neocortical origin of pilomotor seizures in association with an infiltrating glioma: a case confirmed by intracranial electroencephalography monitoring.
  • The authors present the first case in which intracranial electroencephalography monitoring was used to confirm pilomotor seizures of temporal neocortical origin in association with an infiltrating tumor.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Electroencephalography. Epilepsy, Temporal Lobe. Piloerection

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  • (PMID = 20345219.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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74. Gupta RK, Hasan KM, Mishra AM, Jha D, Husain M, Prasad KN, Narayana PA: High fractional anisotropy in brain abscesses versus other cystic intracranial lesions. AJNR Am J Neuroradiol; 2005 May;26(5):1107-14
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  • [Title] High fractional anisotropy in brain abscesses versus other cystic intracranial lesions.
  • BACKGROUND AND PURPOSE: It is known that intracranial mass lesions are relatively isotropic on diffusion-weighted imaging.
  • METHODS: We performed diffusion tensor imaging (DTI) in 12 patients with cystic intracranial lesions (pyogenic abscess, n = 5; cysticercus cysts, n = 2; and low-grade astrocytoma, n = 5).
  • CONCLUSION: Brain abscess cavity shows regions of increased FA values with restricted mean diffusivity compared with other cystic intracranial lesions.

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  • (PMID = 15891168.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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75. Scheithauer BW, Erdogan S, Rodriguez FJ, Burger PC, Woodruff JM, Kros JM, Gokden M, Spinner RJ: Malignant peripheral nerve sheath tumors of cranial nerves and intracranial contents: a clinicopathologic study of 17 cases. Am J Surg Pathol; 2009 Mar;33(3):325-38
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  • [Title] Malignant peripheral nerve sheath tumors of cranial nerves and intracranial contents: a clinicopathologic study of 17 cases.
  • All but 3 lesions were intracranial.
  • One patient was irradiated for hypothalamic pilocytic astrocytoma and another for cervical Hodgkin disease.

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  • (PMID = 19065105.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Ferroir JP, Marro B, Belkacemi Y, Stilhart B, Schlienger M: [Cerebral infarction related to intracranial radiation arteritis twenty-four years after encephalic radiation therapy]. Rev Neurol (Paris); 2007 Jan;163(1):96-8

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  • [Title] [Cerebral infarction related to intracranial radiation arteritis twenty-four years after encephalic radiation therapy].
  • We report a case of a resolutive late cerebral ischemic event, related to radiation induced vasculopathy of the left posterior cerebral artery, documented by MRI, situated in the irradiated volume 24 years before, for an astrocytome with malignant potential.
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / radiotherapy. Brain Neoplasms / radiotherapy. Humans. Male. Radiotherapy / adverse effects. Time Factors

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  • (PMID = 17304179.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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77. Schomas DA, Laack NN, Rao RD, Meyer FB, Shaw EG, O'Neill BP, Giannini C, Brown PD: Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic. Neuro Oncol; 2009 Aug;11(4):437-45
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  • [Title] Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic.
  • Operative pathology revealed pure astrocytoma in 181 patients (58%), oligoastrocytoma in 99 (31%), and oligodendroglioma in 34 (11%).
  • Adverse prognostic factors for OS identified by multivariate analysis were tumor size 5 cm or larger, pure astrocytoma histology, Kernohan grade 2, undergoing less than rSTR, and presentation with sensory motor symptoms.

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  • (PMID = 19018039.001).
  • [ISSN] 1522-8517
  • [Journal-full-title] Neuro-oncology
  • [ISO-abbreviation] Neuro-oncology
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA015083; United States / NCI NIH HHS / CA / P50 CA108961; United States / NCI NIH HHS / CA / P30 CA15083
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2743224
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78. Learn CA, Grossi PM, Schmittling RJ, Xie W, Mitchell DA, Karikari I, Wei Z, Dressman H, Sampson JH: Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity. J Neuroimmunol; 2007 Jan;182(1-2):63-72
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  • [Title] Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity.
  • For the study of malignant glioma, we have previously characterized a highly tumorigenic murine astrocytoma, SMA-560, which arose spontaneously in an inbred, immunocompetent VM/Dk mouse.

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  • (PMID = 17137636.001).
  • [ISSN] 0165-5728
  • [Journal-full-title] Journal of neuroimmunology
  • [ISO-abbreviation] J. Neuroimmunol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA108786; United States / NCI NIH HHS / CA / R01 CA097222; United States / NCI NIH HHS / CA / 1T32-CA-74736; United States / NCI NIH HHS / CA / CA-97222-0; United States / NCI NIH HHS / CA / T32 CA074736; United States / NCI NIH HHS / CA / 1P50CA108786-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS16766; NLM/ PMC1865509
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79. Wu-Chen WY, Jacobs DA, Volpe NJ, Dalmau JO, Moster ML: Intracranial malignancies occurring more than 20 years after radiation therapy for pituitary adenoma. J Neuroophthalmol; 2009 Dec;29(4):289-95
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  • [Title] Intracranial malignancies occurring more than 20 years after radiation therapy for pituitary adenoma.
  • A 63-year-old man developed a malignant astrocytoma of the left optic nerve and chiasm 23 years after partial excision and radiation of a nonsecreting pituitary adenoma.

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  • (PMID = 19952902.001).
  • [ISSN] 1536-5166
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Greco Crasto S, Soffietti R, Rudà R, Cassoni P, Ducati A, Davini O, De Lucchi R, Rizzo L: Diffusion-Weighted Magnetic Resonance Imaging and ADC Maps in the Diagnosis of Intracranial Cystic or Necrotic Lesions. A Retrospective Study on 49 Patients. Neuroradiol J; 2007 Dec 31;20(6):666-75

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  • [Title] Diffusion-Weighted Magnetic Resonance Imaging and ADC Maps in the Diagnosis of Intracranial Cystic or Necrotic Lesions. A Retrospective Study on 49 Patients.
  • Eleven tumours (11/44) appeared hyperintense on DWI: eight metastases from lung cancer (mean ADC value 0.86 mm(2)/s, range 0.75-1.2 mm(2)/s), two GBMs (mean 0.7 mm(2)/s, range 0.67-0.76 mm(2)/s) and one anaplastic astrocytoma (ADC value 1.24 mm(2)/s).

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  • (PMID = 24300002.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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81. Beetz C, Bergner S, Brodoehl S, Brodhun M, Ewald C, Kalff R, Krüger J, Patt S, Kiehntopf M, Deufel T: Outcome-based profiling of astrocytic tumours identifies prognostic gene expression signatures which link molecular and morphology-based pathology. Int J Oncol; 2006 Nov;29(5):1183-91
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  • Astrocytomas are intracranial malignancies for which invasive growth and high motility of tumour cells preclude total resection; the tumours usually recur in a more aggressive and, eventually, lethal form.
  • [MeSH-major] Astrocytoma / mortality. Biomarkers, Tumor / analysis. Brain Neoplasms / mortality. Gene Expression Profiling. Genes, Neoplasm / genetics

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  • (PMID = 17016650.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / RNA, Neoplasm
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82. Berhouma M: Management of subependymal giant cell tumors in tuberous sclerosis complex: the neurosurgeon's perspective. World J Pediatr; 2010 May;6(2):103-10
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  • The data were collected after a bibliography made using PubMed/Medline with these terms: subependymal, subependymal giant cell astrocytoma, subependymal giant cell tumor, and tuberous sclerosis complex.
  • CONCLUSIONS: An earlier diagnosis of SGCT in neurologically asymptomatic children with TSC may allow a precocious surgical removal of the tumor before the installation of increased intracranial pressure signs, an attitude that is being progressively adopted to lessen the morbimortality rate.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Tuberous Sclerosis / complications
  • [MeSH-minor] Algorithms. Child. Humans. Hydrocephalus / etiology. Intracranial Hypertension / etiology. Mutation. Neurosurgical Procedures. Tumor Suppressor Proteins / genetics

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  • (PMID = 20490765.001).
  • [ISSN] 1867-0687
  • [Journal-full-title] World journal of pediatrics : WJP
  • [ISO-abbreviation] World J Pediatr
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein
  • [Number-of-references] 60
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83. Nguyen C, Borruat FX: Bilateral peripapillary subretinal neovessel membrane associated with chronic papilledema: report of two cases. Klin Monbl Augenheilkd; 2005 Mar;222(3):275-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Increased intracranial pressure (ICP) usually results in headaches and papilledema with infrequent loss of visual acuity.
  • Cerebral imaging revealed a pilocytic astrocytoma and hydrocephaly.
  • Severe papilledema and PSNVM were present in both eyes due to idiopathic intracranial hypertension.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Hydrocephalus / complications. Intracranial Hypertension / complications. Optic Disk / blood supply. Papilledema / complications. Retinal Neovascularization / complications. Vision Disorders / etiology


84. Dunn IF, Woodworth GF, Siddiqui AH, Smith ER, Vates GE, Day AL, Goumnerova LC: Traumatic pericallosal artery aneurysm: a rare complication of transcallosal surgery. Case report. J Neurosurg; 2007 Feb;106(2 Suppl):153-7
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  • Traumatic intracranial aneurysms are rare in adults but account for up to 33% of all aneurysms encountered in a pediatric population.
  • Pericallosal aneurysms following a penetrating intracranial injury have also been described, and the resultant lesion in some cases can be a pseudoaneurysm.
  • This 6-year-old boy underwent resection of a hypothalamic pilocytic astrocytoma, which was approached via the transcallosal corridor.
  • [MeSH-major] Astrocytoma / surgery. Corpus Callosum / blood supply. Hypothalamic Neoplasms / surgery. Intracranial Aneurysm / etiology. Intraoperative Complications

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  • [CommentIn] J Neurosurg Pediatr. 2009 Jun;3(6):542; author reply 542 [19485744.001]
  • (PMID = 17330545.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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85. Papavero L, Hagel C, Grzyska U, Fritsche E, Westphal M: August 2004: 64-year-old man with intermittent paresthesia of the abdomen and of the legs. Brain Pathol; 2005 Jan;15(1):91-2, 95

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  • The histologic examination confirmed the typical pattern of a pilocytic astrocytoma in all specimens.
  • In our surgical experience with 226 intramedullary tumors and with 117 patients affected by intracranial pilocytic astrocytoma this case is unique because of its combination of tumor location, growth pattern and age of the patient.
  • [MeSH-major] Astrocytoma / pathology. Astrocytoma / physiopathology. Paresthesia / etiology. Spinal Cord Neoplasms / physiopathology

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  • (PMID = 15779244.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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86. Santhanam R, Balasubramaniam A, Chandramouli BA: Fatal intratumoral hemorrhage in posterior fossa tumors following ventriculoperitoneal shunt. J Clin Neurosci; 2009 Jan;16(1):135-7

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  • An eight-year-old girl presented with raised intracranial pressure and ataxia caused by vermian astrocytoma with obstructive hydrocephalus.
  • [MeSH-major] Astrocytoma / surgery. Infratentorial Neoplasms / surgery. Intracranial Hemorrhages / etiology. Ventriculoperitoneal Shunt / adverse effects

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  • (PMID = 19013806.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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87. Howes TL, Buatti JM, Kirby PA, Carlisle TL, Ryken TC: Radiation induced adult medulloblastoma: a case report. J Neurooncol; 2006 Nov;80(2):191-4
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  • Adult medulloblastoma is a rare intracranial tumor.
  • Our patient is a 61 year old woman treated with cranial irradiation 15 years previously for a low grade astrocytoma in the left posterior temporal lobe that was recently diagnosed with medulloblastoma in the right cerebellum.
  • [MeSH-minor] Astrocytoma / radiotherapy. Brain Neoplasms / radiotherapy. Craniotomy. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Neurosurgical Procedures. Temporal Lobe / pathology

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  • (PMID = 16710747.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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88. Menkü A, Oktem IS, Kontaş O, Akdemir H: Atypical intracerebral schwannoma mimicking glial tumor: case report. Turk Neurosurg; 2009 Jan;19(1):82-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The initial diagnosis being considered was primary intracranial tumor, including high-grade astrocytoma, metastasis or lymphoma Histopathological examination revealed schwannoma.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Epilepsy / pathology. Magnetic Resonance Imaging. Neurilemmoma / pathology

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  • (PMID = 19263360.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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89. Koga N, Ishikawa H: [Clinical evaluation of primary position upbeat nystagmus]. Nippon Ganka Gakkai Zasshi; 2005 Apr;109(4):205-9

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  • In 7 out of 11 patients, intracranial lesions were identified by computed tomography and magnetic resonance imaging.
  • They were located in the median portion of the cerebellum and medulla oblongata except for one adult patient with astrocytoma.
  • The etiologies were 4 tumors, 3 intracranial vascular disorders, 2 Wernicke encephalopathies, 1 congenital anomaly, and 1 inflammation.
  • [MeSH-minor] Adult. Aged. Astrocytoma / complications. Brain Neoplasms / complications. Cerebellum / pathology. Cerebrovascular Disorders / complications. Child. Child, Preschool. Female. Humans. Male. Medulla Oblongata / pathology. Middle Aged

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  • (PMID = 15859150.001).
  • [ISSN] 0029-0203
  • [Journal-full-title] Nippon Ganka Gakkai zasshi
  • [ISO-abbreviation] Nippon Ganka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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90. Shah M, Park HJ, Gohari AR, Bhatti MT: Loss of myelinated retinal nerve fibers from chronic papilledema. J Neuroophthalmol; 2008 Sep;28(3):219-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • An intracranial pilocytic astrocytoma was diagnosed in a 13-year-old boy after he presented with headaches and visual disturbances.
  • [MeSH-major] Astrocytoma / complications. Hypothalamic Neoplasms / complications. Nerve Fibers, Myelinated / pathology. Optic Atrophy / etiology. Papilledema / complications

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  • (PMID = 18769289.001).
  • [ISSN] 1536-5166
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Muzumdar D, Ventureyra EC: Tonsillar herniation and cervical syringomyelia in association with posterior fossa tumors in children: a case-based update. Childs Nerv Syst; 2006 May;22(5):454-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • They frequently present with raised intracranial pressure and may have tonsillar herniation.
  • CASE REPORT: We describe a case of a pilocytic astrocytoma of the cerebellum in a 13-year-old girl who presented with clinical features of progressively worsening raised intracranial pressure and secondary tonsillar herniation and cervical syringomyelia.
  • CONCLUSIONS: The occurrence of tonsillar herniation and syringomyelia in association with a slow growing benign tumor like pilocytic astrocytoma of the cerebellum is uncommon.
  • [MeSH-major] Astrocytoma. Hernia / etiology. Infratentorial Neoplasms / complications. Palatine Tonsil / pathology. Syringomyelia / etiology

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  • (PMID = 16397818.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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92. Solivera J, Navarro R, Costa JM: Orbital emphysema after endoscopic third ventriculostomy and posterior fossa surgery in the sitting position. Childs Nerv Syst; 2007 Jan;23(1):27-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: We report a 4-year-old girl who presented right orbital emphysema after posterior fossa surgery for pilocytic astrocytoma resection in the sitting position.
  • Our hypothesis is that periorbital emphysema developed due to air passing from the intracranial to the extracranial compartment through the ETV burr hole.
  • [MeSH-major] Astrocytoma / surgery. Hydrocephalus / surgery. Neurosurgical Procedures / adverse effects. Orbital Diseases / etiology. Posture. Ventriculostomy

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  • (PMID = 17089169.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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93. Simal-Julián JA, Sanchis-Martín R, Prat-Acín R, Miranda-Lloret P, Conde-Sardón R, Cárdenas-Ruiz-Valdepeñas E, Beltrán-Giner A: [Spinal pleomorphic xantoastrocytoma. Case report]. Neurocirugia (Astur); 2010 Oct;21(5):390-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The differential imagine diagnosis was established between intramedullary astrocytoma and ependimoma.
  • DISCUSSION AND CONCLUSION: comparing to published cases about intracranial pleomorphic xanthoastrocytomas, spinal pleomorphic xanthoastrocytomas (SPXA) present different epidemiological characteristics.
  • [MeSH-major] Astrocytoma. Spinal Cord Neoplasms

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  • (PMID = 21042690.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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94. Isaacs H: Fetal brain tumors: a review of 154 cases. Am J Perinatol; 2009 Jun;26(6):453-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Next was astrocytoma followed by craniopharyngioma, primitive neuroectodermal tumor, choroid plexus papilloma, meningeal tumors, and ependymoma.
  • The most common presenting findings were macrocephaly and an intracranial mass.
  • Many tumors were inoperable as they occupied much of the intracranial cavity and involved large areas of the brain.
  • [MeSH-minor] Astrocytoma / epidemiology. Craniopharyngioma / epidemiology. Ependymoma / epidemiology. Female. Humans. Meningioma / epidemiology. Neuroectodermal Tumors, Primitive / epidemiology. Papilloma, Choroid Plexus / epidemiology. Pregnancy. Retrospective Studies. Stillbirth / epidemiology. Survival Rate. Teratoma / epidemiology

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  • (PMID = 19396744.001).
  • [ISSN] 1098-8785
  • [Journal-full-title] American journal of perinatology
  • [ISO-abbreviation] Am J Perinatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 101
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95. Grujicic M, Vuckovic N, Vulekovic P, Novakovic B: The basic morphological characteristics of astrocytomas in Vojvodina in the period 2001-2006. J BUON; 2009 Oct-Dec;14(4):625-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The basic morphological characteristics of astrocytomas in Vojvodina in the period 2001-2006.
  • PURPOSE: Astrocytomas are the most common primary intracranial neoplasms.
  • The aim of this investigation was to register the age, sex, tumor localization, frequency and histological types of patients with astrocytomas.
  • METHODS: The investigation was carried out from January 2001 to June 2006 and included 490 consecutive patients of both sexes with diagnosed intracranial tumors, who had undergone surgical treatment at the Neurosurgery Clinic of the Clinical Centre of Vojvodina.
  • Out of 490 patients with diagnosed intracranial tumors, 139 (28.4%) had astrocytomas.
  • RESULTS: Astrocytomas were more frequent in males (63.3%) and were most common in the 50-59-year age group (39.5%).
  • In regard to other histological types of intracranial tumors, astrocytomas were more frequent in males (34.8%).
  • Grade III astrocytomas were most common (55.4%).
  • The frequency of hemorrhage and thrombosis showed a positive correlation with the histological grade of astrocytomas.
  • CONCLUSION: The typical patient with astrocytoma is a male of 50-59 years.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology

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  • (PMID = 20148453.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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96. Kaptigau WM, Ke L: Space-occupying lesions in Papua New Guinea--the CT era. P N G Med J; 2007 Mar-Jun;50(1-2):33-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: There were 42 SOL cases affecting the intracranial space and the spine.
  • There were 6 astrocytomas and 3 meningiomas followed by secondaries, pilocytic astrocytoma and medulloblastoma with 2 cases each.
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Astrocytoma / radiography. Child. Child, Preschool. Female. Humans. Infant. Male. Meningioma / radiography. Middle Aged. Papua New Guinea. Sex Distribution. Tomography, X-Ray Computed. Young Adult

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
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  • (PMID = 19354010.001).
  • [ISSN] 0031-1480
  • [Journal-full-title] Papua and New Guinea medical journal
  • [ISO-abbreviation] P N G Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Papua New Guinea
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97. Makidono A, Kobayashi N, Saida Y, Manabe A, Kawamori J, Suzuki K: Metachronous gliomas following cranial irradiation for mixed germ cell tumors. Childs Nerv Syst; 2009 Jun;25(6):713-8
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, metachronous intracranial double tumors induced by radiation therapy are extremely rare.
  • In here, we report a case of metachronous different gliomas including astrocytoma and glioblastoma following irradiation therapy after 41 and 46 months, respectively.
  • [MeSH-major] Astrocytoma / etiology. Brain Neoplasms / radiotherapy. Cranial Irradiation / adverse effects. Glioblastoma / etiology. Neoplasms, Germ Cell and Embryonal / radiotherapy. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / etiology

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  • (PMID = 19247675.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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98. Shukla K, Parikh B, Shukla J, Trivedi P, Shah B: Accuracy of cytologic diagnosis of central nervous system tumours in crush preparation. Indian J Pathol Microbiol; 2006 Oct;49(4):483-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common tumor in intracranial cavity was astrocytoma (56.68%), followed by meningioma (6.88%), medulloblastoma (5.66%) and ependymoma (5.56%).
  • [MeSH-major] Astrocytoma. Central Nervous System Neoplasms / diagnosis. Cytodiagnosis. Ependymoma. Medulloblastoma. Meningioma. Neurilemmoma

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  • (PMID = 17183833.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] India
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99. Debono B, Derrey S, Rabehenoina C, Proust F, Freger P, Laquerrière A: Primary diffuse multinodular leptomeningeal gliomatosis: case report and review of the literature. Surg Neurol; 2006 Mar;65(3):273-82; discussion 282

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histological examination revealed an anaplastic astrocytoma.
  • [MeSH-major] Astrocytoma / surgery. Meningeal Neoplasms / surgery. Neoplasms, Neuroepithelial / surgery. Peripheral Nervous System Neoplasms / surgery. Spinal Nerve Roots / surgery
  • [MeSH-minor] Brain / pathology. Cerebellum / pathology. Diagnosis, Differential. Fatal Outcome. Humans. Intracranial Pressure / physiology. Male. Meninges / pathology. Middle Aged. Neoplasm Invasiveness / pathology. Neurologic Examination. Prognosis

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  • (PMID = 16488248.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 39
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100. Ramírez-Zamora A, Biller J: Brainstem cavernous malformations: a review with two case reports. Arq Neuropsiquiatr; 2009 Sep;67(3B):917-21

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present one case of 'de novo' brainstem cavernous malformation after radiation therapy adding to the increasing number of reported cases in the medical literature, and the case of a pregnant patient with symptomatic intracranial hemorrhage related to brainstem CMs to illustrate the complex nature in management of these patients, followed by a review of clinical and radiographic characteristics.
  • CMs account for 8-15% of all intracranial and intraspinal vascular malformations.
  • Although traditionally thought to be congenital in origin, CMs may present as acquired lesions particularly after intracranial radiation therapy.
  • [MeSH-major] Brain Stem. Cerebral Hemorrhage / etiology. Intracranial Arteriovenous Malformations / diagnosis. Pregnancy Complications, Cardiovascular / diagnosis
  • [MeSH-minor] Adult. Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Pregnancy. Radiotherapy / adverse effects

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  • (PMID = 19838533.001).
  • [ISSN] 1678-4227
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 40
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