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1. Aragão Mde F, Otaduy MC, Melo RV, Azevedo Filho HR, Victor EG, Silva JL, Araújo N, Leite Cda C, Valença MM: [Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas]. Arq Neuropsiquiatr; 2007 Jun;65(2A):286-94
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  • [Title] [Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas].
  • The choline/N-acetyl-aspartate (Cho/NAA) ratio, obtained by the multivoxel spectroscopy with short echo time (TE), was evaluated, in the histological grading of the brain astrocytomas (grades I, II and III-IV) in comparison with the normal cerebral parenchyma.
  • A significant increase (p<0.05) in the average ratios of Cho/NAA was observed in the three astrocytoma groups studied in relation to normal tissue, having a tendency to increase with the increase in grading, without any statistic significance, which corresponded to: 0.53+/-0.24 in the control group, 1.19+/-0.49 in grade I, 1.58+/-0.65 in grade II and 5.13+/-8.12 in the high grade group (grades III-IV), with variation in the values encountered.
  • [MeSH-major] Aspartic Acid / metabolism. Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Magnetic Resonance Spectroscopy / methods

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  • (PMID = 17607430.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] por
  • [Publication-type] Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Protons; 30KYC7MIAI / Aspartic Acid; N91BDP6H0X / Choline
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2. Li HM, Hsu SS, Wang JS, Weng MJ, Fu JH, Chen CK, Lai PH: Cerebral pilocytic astrocytoma with spontaneous intracranial hemorrhage in adults. J Chin Med Assoc; 2008 Nov;71(11):587-93
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  • [Title] Cerebral pilocytic astrocytoma with spontaneous intracranial hemorrhage in adults.
  • Pilocytic astrocytomas are found predominantly in the pediatric population; reports of these tumors are extremely rare in adults.
  • We report 2 cases of adult pilocytic astrocytoma with intracranial hemorrhage.
  • Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a well-enhanced and circumscribed cystic hemorrhagic tumor with mural nodule over the cerebral hemisphere region.
  • The measured relative cerebral blood volume ratios of the mural nodules in these 2 cases were, respectively, 1.34 and 2.81 when compared with normal white matter.
  • After surgical resection, microscopic examination of the lesions showed pilocytic astrocytomas.
  • Since pilocytic astrocytoma and other cystic tumors with mural nodule (such as hemangioblastoma) have similar findings on conventional CT and MRI, PWI is helpful in the differential diagnosis.
  • The literature on hemorrhagic pilocytic astrocytoma is also reviewed.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Cerebral Hemorrhage / etiology

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  • (PMID = 19015059.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China (Republic : 1949- )
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3. Tsutsumi S, Higo T, Kondo A, Abe Y, Yasumoto Y, Ito M: Atypical cervical astrocytoma manifesting as occipitalgia. Neurol Med Chir (Tokyo); 2007 Aug;47(8):371-4
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  • [Title] Atypical cervical astrocytoma manifesting as occipitalgia.
  • Cerebral magnetic resonance (MR) imaging showed no corresponding lesions.
  • Histological examination identified diffuse astrocytoma.
  • Cervical astrocytoma of subpial location is a very rare cause of headache in adults.
  • [MeSH-major] Astrocytoma / complications. Astrocytoma / pathology. Headache / etiology. Spinal Cord / pathology. Spinal Cord Neoplasms / complications. Spinal Cord Neoplasms / pathology

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  • (PMID = 17721055.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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4. Shingu T, Akiyama Y, Daisu M, Maruyama N, Matsumoto Y, Miyazaki T, Nagai H, Yamamoto Y, Yamasaki T, Yoshida M, Maruyama R, Moritake K: Symptomatic hemorrhage associated with recurrent pilocytic astrocytoma with granulation tissue--case report. Neurol Med Chir (Tokyo); 2007 May;47(5):222-8
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  • [Title] Symptomatic hemorrhage associated with recurrent pilocytic astrocytoma with granulation tissue--case report.
  • A 51-year-old woman had been followed up for 10 years for recurrence of pilocytic astrocytoma 5 years after the initial treatment consisting of subtotal resection, chemotherapy, and radiation therapy.
  • Histological examination confirmed recurrent pilocytic astrocytoma with organizing hematoma and granulation tissue.
  • Although neither symptomatic hemorrhage nor late benign recurrence is common, careful long-term follow up is necessary for patients with pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Hemorrhage / etiology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 17527050.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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5. D'Angelo A, Capucchio MT, Ferroglio E, Jaggy A: Astrocytoma in a chamois. Schweiz Arch Tierheilkd; 2005 Oct;147(10):453-5
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  • [Title] Astrocytoma in a chamois.
  • Astrocytomas represent the most common cerebral tumors in humans and in animals, and the fibrillary cytological subtype is the most frequently observed.
  • In this report and for the first time, a thalamic astrocytoma is described in a chamois showing depressed mentation, pleurothotonus and circling to the right side.
  • [MeSH-major] Astrocytoma / veterinary. Brain Neoplasms / veterinary. Goat Diseases / diagnosis. Rupicapra

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  • (PMID = 16259411.001).
  • [ISSN] 0036-7281
  • [Journal-full-title] Schweizer Archiv für Tierheilkunde
  • [ISO-abbreviation] Schweiz. Arch. Tierheilkd.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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6. Tanaka K, Sasayama T, Kawamura A, Kondoh T, Kanomata N, Kohmura E: Isolated oculomotor nerve paresis in anaplastic astrocytoma with exophytic invasion. Neurol Med Chir (Tokyo); 2006 Apr;46(4):198-201
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  • [Title] Isolated oculomotor nerve paresis in anaplastic astrocytoma with exophytic invasion.
  • The histological diagnosis was anaplastic astrocytoma.
  • [MeSH-major] Astrocytoma / complications. Oculomotor Nerve Diseases / etiology. Supratentorial Neoplasms / complications. Temporal Lobe
  • [MeSH-minor] Adult. Astrocytes / pathology. Biomarkers, Tumor / analysis. Brain Stem / pathology. Cerebral Arteries / pathology. Cisterna Magna / pathology. Dominance, Cerebral / physiology. Humans. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness / pathology. Nerve Compression Syndromes / diagnosis. Nerve Compression Syndromes / etiology. Nerve Compression Syndromes / pathology. Nerve Compression Syndromes / surgery. Neuronavigation. Oculomotor Nerve / pathology. Oculomotor Nerve / surgery. Pons / pathology

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  • (PMID = 16636512.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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7. Bence M, Kereszturi E, Mozes V, Sasvari-Szekely M, Keszler G: Hypoxia-induced transcription of dopamine D3 and D4 receptors in human neuroblastoma and astrocytoma cells. BMC Neurosci; 2009;10:92
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  • [Title] Hypoxia-induced transcription of dopamine D3 and D4 receptors in human neuroblastoma and astrocytoma cells.
  • BACKGROUND: Dopaminergic pathways that influence mood and behaviour are severely affected in cerebral hypoxia.
  • In order to clarify the hypoxic sensitivity of key dopaminergic genes, we aimed to study their transcriptional regulation in the context of neuroblastoma and astrocytoma cell lines exposed to 1% hypoxia.
  • [MeSH-minor] Astrocytoma. Blotting, Western. Cell Line, Tumor. Gene Transfer Techniques. Humans. Hypoxia-Inducible Factor 1, alpha Subunit / genetics. Hypoxia-Inducible Factor 1, alpha Subunit / metabolism. Immunohistochemistry. Neuroblastoma. Reverse Transcriptase Polymerase Chain Reaction. Transcriptional Activation

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  • (PMID = 19653907.001).
  • [ISSN] 1471-2202
  • [Journal-full-title] BMC neuroscience
  • [ISO-abbreviation] BMC Neurosci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DRD3 protein, human; 0 / DRD4 protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Receptors, Dopamine D3; 137750-34-6 / Receptors, Dopamine D4
  • [Other-IDs] NLM/ PMC3224682
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8. Xiangsong Z, Changhong L, Weian C, Dong Z: PET Imaging of cerebral astrocytoma with 13N-ammonia. J Neurooncol; 2006 Jun;78(2):145-51
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  • [Title] PET Imaging of cerebral astrocytoma with 13N-ammonia.
  • We performed this study in order to assess the clinical potential of (13)N-ammonia PET in patients with cerebral astrocytoma.
  • METHODS: Dynamic 13N-ammonia PET was performed in 25 patients with suspected cerebral gliomas or recurrent cerebral astrocytomas (19 male and 6 female patients; age range 18-64 years) detected by MRI.
  • RESULTS: Six out of nine cases of low-grade gliomas were detected with 13N-ammonia PET, and three non-astrocytoma low-grade gliomas were not detected with 13N-ammonia PET.
  • All 11 high-grade astrocytomas exhibited markedly increased uptake of 13N-ammonia.
  • There were the significant differences between the T/W ratios and PI in low-grade astrocytomas and that in non-neoplastic lesions (T/W ratios: 2.00+/-0.42, n=6 vs. 0.97+/-0.11, n=5, P<0.01; PI: 1.89+/-0.37, n=6 vs. 0.99+/-0.03, n=5, P<0.01).
  • CONCLUSIONS: There is a substantial uptake of 13N-ammonia in cerebral astrocytomas.
  • 13N-ammonia PET may enable differentiation between low- and high-grade astrocytomas, and has the potential to enable differentiation between low-grade astrocytomas and non-neoplastic lesions.
  • [MeSH-major] Ammonia. Astrocytoma / radionuclide imaging. Brain Neoplasms / radionuclide imaging. Nitrogen Isotopes. Positron-Emission Tomography / methods

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  • (PMID = 16739028.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Nitrogen Isotopes; 0 / Radiopharmaceuticals; 7664-41-7 / Ammonia
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9. Szeifert GT, Prasad D, Kamyrio T, Steiner M, Steiner LE: The role of the Gamma Knife in the management of cerebral astrocytomas. Prog Neurol Surg; 2007;20:150-63
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  • [Title] The role of the Gamma Knife in the management of cerebral astrocytomas.
  • The aim of this study was to assess the role of Gamma Knife radiosurgery in the complex management of cerebral astrocytomas.
  • Out of a series with more than 1,000 brain tumor cases treated at the Lars Leksell Center for Gamma Knife Surgery, UVA, 74 astrocytomas were selected for the present review.
  • The tumor either disappeared or decreased in 60% of grade 1 astrocytomas (n = 15), and 71% tumor control was achieved in grade 2 astrocytomas (n = 17) following radiosurgery.
  • Results of the present analysis suggest that stereotactic radiosurgery represents an alternative or supplementary treatment modality to conventional surgery in small-volume low-grade astrocytomas especially in deep-seated critical locations.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Radiosurgery / methods

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  • (PMID = 17317983.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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10. Hu CH, Fang XM, Hu XY, Cui L: Analysis of the mismatched manifestation between rCBF and rCBV maps in cerebral astrocytomas. Clin Imaging; 2009 Nov-Dec;33(6):417-23
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  • [Title] Analysis of the mismatched manifestation between rCBF and rCBV maps in cerebral astrocytomas.
  • OBJECTIVE: To explore the mismatched manifestation between regional cerebral blood flow (rCBF) and regional cerebral blood volume (rCBV) of astrocytomas.
  • METHODS: Both conventional and perfusion CT were performed on 29 patients with pathologically confirmed astrocytomas (15 cases in Grades I-II, 14 cases in Grades III-IV).
  • Time-density curves were plotted, cerebral blood flow and volume maps were generated, and the values between rCBF and rCBV in the same region of interest (ROI) were compared.
  • RESULTS: Twelve low-grade astrocytomas showed low or medium values of both rCBF (46.95+/-22.92 ml 100 g(-1) mm(-1)) and rCBV (5.74+/-3.61 ml 100 g(-1)); 12 high-grade astrocytomas showed high values of both rCBF (95.44+/-42.58 ml 100 g(-1) min(-1)) and rCBV (9.24+/-5.32 ml 100g(-1)).
  • However, the remaining five astrocytomas were mismatched, showing reduced rCBF value and increased rCBV value in the same ROI.
  • CONCLUSIONS: The mismatched manifestation between rCBF and rCBV occasionally exists in some areas of astrocytomas.
  • Hence, attention should be paid to assessments in preoperative grading of astrocytomas and in monitoring therapeutic effects.
  • [MeSH-major] Astrocytoma / physiopathology. Astrocytoma / radiography. Brain Neoplasms / physiopathology. Brain Neoplasms / radiography. Cerebrovascular Circulation. Perfusion Imaging / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 19857800.001).
  • [ISSN] 1873-4499
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Xiangsong Z, Weian C: Differentiation of recurrent astrocytoma from radiation necrosis: a pilot study with 13N-NH3 PET. J Neurooncol; 2007 May;82(3):305-11
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  • [Title] Differentiation of recurrent astrocytoma from radiation necrosis: a pilot study with 13N-NH3 PET.
  • The present study assessed the role of (13)N-NH(3) PET in differentiating recurrent cerebral astrocytoma from radiation necrosis.
  • METHODS: Seven patients, who were previously treated with conventional external-beam radiation therapy after surgical resection for cerebral astrocytomas, and showed the enhancing brain lesions on T1-weighted gadiolinium-enhanced MR studies performed in 6 months or above after the radiotherapies, were examined prospectively with (13)N-NH(3) and FDG PET.
  • The other lesion with anaplastic astrocytoma showed moderately increased (13)N-NH(3) uptake (grade = 4), but slightly less FDG uptake than surrounding area (grade = 2).
  • CONCLUSIONS: The recurrent astrocytomas showed increased (13)N-NH(3) uptake, and the radiation necrosis showed absent or less (13)N-NH(3) uptake, and (13)N-NH(3) seem superior to (18)F-FDG for this purpose, suggesting that (13)N-NH(3) is a promising tracer for separating radiation necrosis from astrocytoma recurrence.
  • [MeSH-major] Astrocytoma / pathology. Brain Diseases / pathology. Brain Neoplasms / pathology. Neoplasm Recurrence, Local / diagnosis. Nitrogen Radioisotopes

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  • (PMID = 17120157.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Nitrogen Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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12. Shinohara Y, Kinoshita T, Kinoshita F, Moroi J, Yoshida Y, Nakazato Y: F-18 FDG-PET imaging of dysembryoplastic neuroepithelial tumor-like astrocytoma. Clin Nucl Med; 2009 Oct;34(10):700-2
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  • [Title] F-18 FDG-PET imaging of dysembryoplastic neuroepithelial tumor-like astrocytoma.
  • Cerebral astrocytoma needs to be distinguished from dysembryoplastic neuroepithelial tumor (DNT) when a well-demarcated, cortically based and pseudo-cystic tumor with minimal mass effect is demonstrated on magnetic resonance imaging.
  • We report an unusual case of DNT-like astrocytoma.
  • FDG-positron emission tomography is useful for identifying the malignant potential of DNT-like astrocytoma.
  • [MeSH-major] Astrocytoma / radionuclide imaging. Fluorodeoxyglucose F18. Neoplasms, Neuroepithelial / radionuclide imaging. Positron-Emission Tomography

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  • (PMID = 19893407.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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13. Faria AV, Azevedo GC, Zanardi VA, Ghizoni E, Queiroz LS: Dissemination patterns of pilocytic astrocytoma. Clin Neurol Neurosurg; 2006 Sep;108(6):568-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dissemination patterns of pilocytic astrocytoma.
  • Two patients with multifocal pilocytic astrocytoma diagnosed by magnetic resonance imaging (MRI) and confirmed by histopathological examination are reported.
  • They presented distinct sites and mechanisms of metastasis: to distant ventricles through the cerebral spinal fluid (CSF) in patient 1 and to contralateral parenchyma, possibly through white matter tracts, in patient 2, a pathway not so far reported in pilocytic astrocytoma.
  • Early detection of multifocal pilocytic astrocytoma by MRI may change treatment strategies and improve prognosis.
  • [MeSH-major] Astrocytoma / secondary. Brain Neoplasms / pathology


14. Darwish B, Arbuckle S, Kellie S, Besser M, Chaseling R: Desmoplastic infantile ganglioglioma/astrocytoma with cerebrospinal metastasis. J Clin Neurosci; 2007 May;14(5):498-501
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic infantile ganglioglioma/astrocytoma with cerebrospinal metastasis.
  • Desmoplastic infantile ganglioglioma and astrocytoma (DIG/DIA) are rare intracranial tumours of early childhood that involve superficial cerebral cortex and leptomeninges.


15. Shi Y, Morgenstern N: Granular cell astrocytoma. Arch Pathol Lab Med; 2008 Dec;132(12):1946-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell astrocytoma.
  • Granular cell astrocytoma (GCA) is a rare type of malignant brain tumor with distinct morphologic features and aggressive clinical behavior.
  • Almost all GCAs occur in the cerebral hemispheres.
  • The most important differential diagnoses include a number of reactive lesions such as cerebral infarction, multiple sclerosis, and progressive multifocal leukoencephalopathy.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Granular Cell Tumor / pathology

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  • (PMID = 19061297.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins
  • [Number-of-references] 22
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16. Simonelli M, Banna G, Navarria P, Di Ieva A, Zucali P, De Vincenzo F, Gaetani P, Condorelli R, Rodriguez Y Baena R, Scorsetti M, Santoro A: Addition of temozolomide to radiotherapy for treatment of newly diagnosed anaplastic gliomas. J Clin Oncol; 2009 May 20;27(15_suppl):e13037

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e13037 Background: Anaplastic astrocytoma (AA), oligodendroglioma (AOD), and oligoastrocytoma (AOA) are rare tumors showing variable outcome due to their histological heterogeneity and different chemo- and radio-sensitivity.
  • In 1 patient with AOD RT and concomitant TMZ were interrupted at 44 Gy because of cerebral oedema, while in 1 patient with AA maintenance TMZ was suspended due to cumulative myelosuppression.

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  • (PMID = 27962859.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Hauck EF, McGinnis M, Nauta HJ: Cerebral phaeohyphomycosis mimics high-grade astrocytoma. J Clin Neurosci; 2008 Sep;15(9):1061-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebral phaeohyphomycosis mimics high-grade astrocytoma.
  • The incidence of cerebral phaeohyphomycosis, an infection caused by a dark-pigmented fungus, is increasing.
  • We report two cases to increase the awareness of cerebral phaeohyphomycosis in the clinical neurosciences.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Abscess / microbiology. Brain Abscess / pathology. Brain Neoplasms / diagnosis. Central Nervous System Fungal Infections / microbiology. Central Nervous System Fungal Infections / pathology

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  • (PMID = 18614370.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Antifungal Agents
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18. Buccoliero AM, Franchi A, Castiglione F, Gheri CF, Mussa F, Giordano F, Genitori L, Taddei GL: Subependymal giant cell astrocytoma (SEGA): Is it an astrocytoma? Morphological, immunohistochemical and ultrastructural study. Neuropathology; 2009 Feb;29(1):25-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subependymal giant cell astrocytoma (SEGA): Is it an astrocytoma? Morphological, immunohistochemical and ultrastructural study.
  • Subependymal giant-cell astrocytoma (SEGA) is a rare intra-ventricular low-grade tumor which frequently occurs as a manifestation of tuberous sclerosis complex.
  • In spite of this, in the recently revised WHO classification of the CNS tumors, SEGA has been still included in the group of astrocytomas.
  • [MeSH-major] Astrocytoma / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adolescent. Brain Neoplasms / chemistry. Brain Neoplasms / classification. Brain Neoplasms / pathology. Brain Neoplasms / ultrastructure. Cerebral Ventricle Neoplasms / chemistry. Cerebral Ventricle Neoplasms / classification. Cerebral Ventricle Neoplasms / pathology. Cerebral Ventricle Neoplasms / ultrastructure. Child. Child, Preschool. Female. Humans. Immunohistochemistry. Infant. Intermediate Filaments / ultrastructure. Male. Nerve Tissue Proteins / analysis. Neurofilament Proteins / analysis. Neuroglia / pathology. Neuroglia / ultrastructure. Phosphopyruvate Hydratase / analysis. Synaptophysin / analysis

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  • (PMID = 18564101.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Nerve Tissue Proteins; 0 / Neurofilament Proteins; 0 / Synaptophysin; EC 4.2.1.11 / Phosphopyruvate Hydratase
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19. Temel SG, Kahveci Z: Cyclooxygenase-2 expression in astrocytes and microglia in human oligodendroglioma and astrocytoma. J Mol Histol; 2009 Oct;40(5-6):369-77
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  • [Title] Cyclooxygenase-2 expression in astrocytes and microglia in human oligodendroglioma and astrocytoma.
  • In normal cerebral cortex cox-2 is present only in neurons, but not in the glial or vascular endothelial cells.
  • For this purpose we employed dual immunohistochemistry for cox-2 and GFAP (astrocyte) or LCA-MAC (microglia-macrophage) in archival formalin-fixed, paraffin embedded human tissue diagnosed as oligodendroglioma and/or astrocytoma.
  • It may be speculated that the induction of cox-2 in microglia may contribute to the deleterious effects of prostanoids in cerebral edema formation during the progression of oligodendrogliomas.
  • [MeSH-major] Astrocytes / enzymology. Astrocytoma / enzymology. Cyclooxygenase 2 / metabolism. Microglia / enzymology. Oligodendroglioma / enzymology

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  • (PMID = 20052522.001).
  • [ISSN] 1567-2387
  • [Journal-full-title] Journal of molecular histology
  • [ISO-abbreviation] J. Mol. Histol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human; EC 3.1.3.48 / Antigens, CD45
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20. Omura T, Nawashiro H, Osada H, Shima K, Tsuda H, Shinsuke A: Pilomyxoid astrocytoma of the fourth ventricle in an adult. Acta Neurochir (Wien); 2008 Nov;150(11):1203-6; discussion 1206

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pilomyxoid astrocytoma of the fourth ventricle in an adult.
  • Pilomyxoid astrocytomas have been identified as a variant of pilocytic astrocytoma.
  • This tumour corresponds to a WHO grade II neoplasm whereas pilocytic astrocytoma corresponds to WHO grade I.
  • Pilomyxoid astrocytomas are not limited to the hypothalamic/chiasmatic region in children.
  • Additional knowledge and recognition of this entity is necessary to improve treatment of pilomyxoid astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology

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  • (PMID = 18958385.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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21. Beppu T, Sato Y, Uesugi N, Kuzu Y, Ogasawara K, Ogawa A: Desmoplastic infantile astrocytoma and characteristics of the accompanying cyst. Case report. J Neurosurg Pediatr; 2008 Feb;1(2):148-51
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  • [Title] Desmoplastic infantile astrocytoma and characteristics of the accompanying cyst. Case report.
  • A desmoplastic infantile astrocytoma (DIA) is an extremely rare tumor that comprises a solid astrocytic tumor accompanied by a large cyst and involves the superficial cerebral cortex and leptomeninges in infants.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Diseases / diagnosis. Brain Neoplasms / diagnosis. Cysts / diagnosis
  • [MeSH-minor] Arachnoid / pathology. Astrocytes / pathology. Capillaries / pathology. Cerebral Cortex / pathology. Contrast Media. Dura Mater / pathology. Frontal Lobe / pathology. Gliosis / pathology. Humans. Image Enhancement. Infant. Lymphocytes / pathology. Magnetic Resonance Imaging. Male. Pia Mater / pathology

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  • (PMID = 18352787.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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22. Miyamoto S, Mikuni N, Yamada K, Takahashi JA, Hashimoto N: Radical resection for intrinsic midbrain pilocytic astrocytoma: report of two cases. Acta Neurochir (Wien); 2005 Jan;147(1):93-7; discussion 97
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radical resection for intrinsic midbrain pilocytic astrocytoma: report of two cases.
  • It is known that the prognosis of pilocytic astrocytoma is relatively good if radical resection can be achieved without severe complications.
  • In order to remove pilocytic astrocytoma within the midbrain radically, we used microsurgical techniques.
  • METHOD: Two patients with intrinsic pilocytic astrocytomas located at the midbrain were operated on.
  • The subtemporal approach was used with a point of entry on the lateral surface of the midbrain just behind the cerebral peduncle.
  • FINDINGS: In both patients, intrinsic pilocytic astrocytoma was grossly totally removed with minimal permanent morbidity.
  • CONCLUSIONS: Surgical cure can be accomplished in some cases of midbrain pilocytic astrocytoma, even if the lesions are intrinsic to the midbrain.
  • A long-term follow up with a larger number of patients is needed to establish the significance of radical resection for intrinsic midbrain pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / surgery. Brain Stem Neoplasms / surgery. Microsurgery / methods

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  • (PMID = 15309583.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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23. Chong DY, Hirunwiwatkul P, McKeever PE, Trobe JD: Papilledema in obstructive hydrocephalus caused by giant cell astrocytoma of tuberous sclerosis. J Neuroophthalmol; 2007 Mar;27(1):50-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papilledema in obstructive hydrocephalus caused by giant cell astrocytoma of tuberous sclerosis.
  • Total excision of the mass led to a pathologic diagnosis of giant cell astrocytoma.
  • Although the patient apparently escaped visual loss, other reports affirm that giant cell astrocytoma, a common tumor in TS, may go undetected for long enough to produce irreversible optic neuropathy from chronic papilledema.
  • [MeSH-major] Astrocytoma / complications. Cerebral Ventricle Neoplasms / complications. Hydrocephalus / complications. Papilledema / etiology. Tuberous Sclerosis / complications


24. Fu JB, Parsons HA, Shin KY, Guo Y, Konzen BS, Yadav RR, Smith DW: Comparison of functional outcomes in low- and high-grade astrocytoma rehabilitation inpatients. Am J Phys Med Rehabil; 2010 Mar;89(3):205-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of functional outcomes in low- and high-grade astrocytoma rehabilitation inpatients.
  • OBJECTIVES: To compare inpatient rehabilitation outcomes between patients with low- and high-grade astrocytoma.
  • A high-grade (21 of 443 patients) and low-grade astrocytoma (21 of 24 patients) group were matched on three of five criteria in the order of importance: area of brain involvement (divided into left cerebral, right cerebral, midline and/or bilateral cerebral, and infratentorial), single vs. multiple intracranial neurosurgical procedures, age (within 10 yrs), period of rehabilitation admission (within 3 yrs), and sex.
  • The high-grade group had significantly (P < 0.05) higher total gain and longer stay in inpatient rehabilitation (mean +/- standard deviation, 21.7 +/- 10.1 vs. 13.0 +/- 9.3 and 13 +/- 7.1 day vs. 9 +/- 6.2 days, respectively) than did the low-grade astrocytoma group.
  • CONCLUSIONS: Compared with patients with low-grade astrocytoma, patients with high-grade astrocytoma had higher total functional independence measure gain but also longer lengths of stay.

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  • (PMID = 20068429.001).
  • [ISSN] 1537-7385
  • [Journal-full-title] American journal of physical medicine & rehabilitation
  • [ISO-abbreviation] Am J Phys Med Rehabil
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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25. Zakrzewski K, Biernat W, Liberski PP, Polis L, Nowoslawska E: Pilocytic astrocytoma as a predominant component of a recurrent complex type DNT. Folia Neuropathol; 2009;47(3):284-8
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  • [Title] Pilocytic astrocytoma as a predominant component of a recurrent complex type DNT.
  • Dysembryoplastic neuroepithelial tumour (DNT) is a benign lesion of the cerebral hemispheres usually presenting minimal biological activity after surgical excision.
  • In the recurrent lesion we identified pilocytic astrocytoma (PA) as a predominant component of the tumour.

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  • (PMID = 19813149.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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26. Andrychowski J, Taraszewska A, Czernicki Z, Jurkiewicz J, Netczuk T, Dabrowski P: Ten years observation and treatment of multifocal pilocytic astrocytoma. Folia Neuropathol; 2009;47(4):362-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ten years observation and treatment of multifocal pilocytic astrocytoma.
  • Pilocytic astrocytoma (PA) usually occurs in younger patients.
  • It is a benign, generally well-delineated, WHO grade I tumour with favorable prognosis, which makes it different from diffuse astrocytomas, classified as higher grades of malignancy.
  • Neuroradiological study revealed cerebral tumour in the right temporal lobe, then the first temporal lobe surgery followed by re-operation and radiotherapy was performed.
  • Initially, the histopathological diagnosis of ganglioglioma was suggested for primary tumour, finally the diagnosis of pilocytic astrocytoma for both recurrent and primary tumour was established.
  • Histopathological examinations of the excised foci from spinal canal revealed neoplasm consistent with WHO grade I pilocytic astrocytoma.

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  • (PMID = 20054789.001).
  • [ISSN] 1509-572X
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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27. Chen L, Wang Y, Zhu XZ: [Pilomyxoid astrocytoma: a clinicopathologic study of three cases]. Zhonghua Bing Li Xue Za Zhi; 2006 Dec;35(12):727-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pilomyxoid astrocytoma: a clinicopathologic study of three cases].
  • OBJECTIVE: To study the clinicopathologic features of pilomyxoid astrocytoma (PmA).
  • The biphasic pattern noted in a classic pilocytic astrocytoma was not found in PmA.
  • CONCLUSIONS: PmA is a distinctive variant of pilocytic astrocytoma with subtle histologic differences.
  • Compared with conventional pilocytic astrocytoma, PmA behaves more aggressively.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology. Optic Nerve Glioma / pathology. Third Ventricle / pathology

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  • (PMID = 17374256.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen
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28. Haris M, Husain N, Singh A, Husain M, Srivastava S, Srivastava C, Behari S, Rathore RK, Saksena S, Gupta RK: Dynamic contrast-enhanced derived cerebral blood volume correlates better with leak correction than with no correction for vascular endothelial growth factor, microvascular density, and grading of astrocytoma. J Comput Assist Tomogr; 2008 Nov-Dec;32(6):955-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dynamic contrast-enhanced derived cerebral blood volume correlates better with leak correction than with no correction for vascular endothelial growth factor, microvascular density, and grading of astrocytoma.
  • OBJECTIVE: To look for the impact of leak correction on correlation of perfusion indices with microvessel density (MVD) and vascular endothelial growth factor (VEGF) in astrocytomas.
  • METHODS: Dynamic contrast-enhanced magnetic resonance imaging was performed in 64 patients with varying grades of astrocytoma.
  • Perfusion indices (ie, relative cerebral blood volume (rCBV) with and without leak correction, relative cerebral blood flow (rCBF), permeability (k(trans)), and leakage (v(e)) were quantified.
  • RESULTS: Perfusion indices showed significant difference among the astrocytoma grades.
  • The corrected rCBV discriminated 100% low-grade from high-grade astrocytoma, while uncorrected rCBV did this in 95.5% low-grade and 71.4% high-grade astrocytoma.
  • CONCLUSIONS: Corrected rCBV better correlates with grade and is more accurate in discriminating low-grade from high-grade astrocytoma compared with uncorrected rCBV.
  • [MeSH-major] Artifacts. Astrocytoma / pathology. Brain Neoplasms / diagnosis. Brain Neoplasms / metabolism. Gadolinium DTPA. Image Interpretation, Computer-Assisted / methods. Magnetic Resonance Imaging / methods. Vascular Endothelial Growth Factor A / analysis

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  • (PMID = 19204461.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Vascular Endothelial Growth Factor A; K2I13DR72L / Gadolinium DTPA
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29. Lee CS, Huh JS, Sim KB, Kim YW: Cerebellar pilocytic astrocytoma presenting with intratumor bleeding, subarachnoid hemorrhage, and subdural hematoma. Childs Nerv Syst; 2009 Jan;25(1):125-8
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  • [Title] Cerebellar pilocytic astrocytoma presenting with intratumor bleeding, subarachnoid hemorrhage, and subdural hematoma.
  • INTRODUCTION: Massive intracranial hemorrhage is a very rare initial presentation of cerebellar pilocytic astrocytomas.
  • There are no reports in the medical literature on a cerebellar pilocytic astrocytoma presenting with intratumor bleeding (ITB), subarachnoid hemorrhage (SAH), and subdural hematoma (SDH).
  • Microscopic examination of tissue sections revealed a pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Hematoma, Subdural / etiology. Subarachnoid Hemorrhage / etiology
  • [MeSH-minor] Cerebral Hemorrhage / etiology. Cerebral Hemorrhage / surgery. Diagnosis, Differential. Humans. Infant. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18629510.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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30. Uro-Coste E, Ssi-Yan-Kai G, Guilbeau-Frugier C, Boetto S, Bertozzi AI, Sevely A, Lolmede K, Delisle MB: Desmoplastic infantile astrocytoma with benign histological phenotype and multiple intracranial localizations at presentation. J Neurooncol; 2010 May;98(1):143-9
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  • [Title] Desmoplastic infantile astrocytoma with benign histological phenotype and multiple intracranial localizations at presentation.
  • Desmoplastic infantile astrocytoma (DIA) and desmoplastic infantile ganglioglioma (DIG) are rare intracranial tumors that mostly occur in the first 2 years of life and involve superficial cerebral cortex.
  • We report an original observation of a desmoplastic infantile astrocytoma in a 5-year-old boy with multiple localizations on initial presentation, including the unusual subtentorial region.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology

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  • (PMID = 20012157.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Bongiorni L, Arroyo HA, Lubienicki F: [Subependymal nodules-sudependymal giant cell astrocytoma complex in children with tuberous sclerosis]. Medicina (B Aires); 2009;69(1 Pt 1):8-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Subependymal nodules-sudependymal giant cell astrocytoma complex in children with tuberous sclerosis].
  • [Transliterated title] Complejo nódulo subependimario-astrocitoma subependimario gigantocelular en niños con esclerosis tuberosa.
  • The object of this paper is to describe the imaging and clinical characteristics of subependymal nodule (SN) - subependymal giant cell astrocytoma (SGCA) complex in tuberous sclerosis and analyze its evolution in order to attempt early detection and the prevention of intracranial hypertension.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Ventricles / pathology. Tuberous Sclerosis / pathology
  • [MeSH-minor] Adolescent. Cerebral Ventricle Neoplasms / pathology. Cerebral Ventricle Neoplasms / radiography. Cerebral Ventricle Neoplasms / surgery. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Hydrocephalus / etiology. Infant. Intellectual Disability / etiology. Intracranial Hypertension / prevention & control. Male


32. Chen H, Sun XF, Wu JS: [Clinicopathologic study of subependymal giant cell astrocytoma]. Zhonghua Bing Li Xue Za Zhi; 2006 Nov;35(11):656-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinicopathologic study of subependymal giant cell astrocytoma].
  • OBJECTIVE: To study the clinicopathologic features of subependymal giant cell astrocytoma.
  • METHODS: The clinical and pathologic characteristics of 18 cases of subependymal giant cell astrocytoma were retrospectively analyzed.
  • CONCLUSIONS: Subependymal giant cell astrocytoma is a benign brain tumor with distinctive histopathologic features.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology

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  • (PMID = 17374208.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Synaptophysin
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33. Khanani MF, Hawkins C, Shroff M, Dirks P, Capra M, Burger PC, Bouffet E: Pilomyxoid astrocytoma in a patient with neurofibromatosis. Pediatr Blood Cancer; 2006 Mar;46(3):377-80
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  • [Title] Pilomyxoid astrocytoma in a patient with neurofibromatosis.
  • Pilomyxoid astrocytoma (PMA), a recently described variant of low-grade astrocytoma is associated with a high rate of recurrence and a propensity for CSF seeding.
  • [MeSH-major] Astrocytoma / surgery. Cerebral Ventricle Neoplasms / surgery. Neoplasms, Second Primary / surgery. Neurofibromatosis 1 / surgery

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  • (PMID = 15800886.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Josan VA, Timms CD, Rickert C, Wallace D: Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report. J Neurosurg; 2007 Jul;107(1 Suppl):66-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report.
  • Central precocious puberty secondary to a cerebellar astrocytoma is extremely rare.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Puberty, Precocious / etiology
  • [MeSH-minor] Cerebellum / pathology. Cerebellum / surgery. Child, Preschool. Diagnosis, Differential. Dominance, Cerebral. Estradiol / blood. Female. Gonadal Steroid Hormones / blood. Humans. Magnetic Resonance Imaging. Menstruation / physiology

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  • (PMID = 17644924.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gonadal Steroid Hormones; 4TI98Z838E / Estradiol
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35. Ahmad Z, Rauf F, Azad NS, Ahsan A: Subependymal giant cell astrocytoma. J Pak Med Assoc; 2006 Oct;56(10):463-5
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  • [Title] Subependymal giant cell astrocytoma.
  • Subependymal giant cell astrocytomas (SEGAs) are slowly growing tumours corresponding to WHO grade I.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology

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  • (PMID = 17144395.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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36. Grau E, Balaguer J, Canete A, Martinez F, Orellana C, Oltra S, Hernandez M, Castel V: Subtelomeric analysis of pediatric astrocytoma: subchromosomal instability is a distinctive feature of pleomorphic xanthoastrocytoma. J Neurooncol; 2009 Jun;93(2):175-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subtelomeric analysis of pediatric astrocytoma: subchromosomal instability is a distinctive feature of pleomorphic xanthoastrocytoma.
  • Astrocytic neoplasms are genetically heterogeneous; however a low frequency of genomic changes has been found in juvenile pilocytic astrocytoma (PA) in molecular studies.
  • We studied the subtelomeric regions of 19 primary astrocytoma tumors.
  • These genetic differences would likely contribute to the more favorable behavior of PXAs and may be helpful for molecular differential diagnosis of pediatric cerebral tumors.
  • [MeSH-major] Astrocytoma / genetics. Chromosomal Instability / genetics. Glioma / genetics. Telomere / genetics

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  • (PMID = 19099200.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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37. Kondageski C, Pierre-Kahn A, Carbonne B, Brunelle F: Association of a fetal quadrigeminal cyst with a possibly congenital thalamic astrocytoma. Childs Nerv Syst; 2005 Apr;21(4):317-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of a fetal quadrigeminal cyst with a possibly congenital thalamic astrocytoma.
  • CASE REPORT: This article reports on the exceptional association of a fetal quadrigeminal malformative cyst with a possibly congenital pilocytic astrocytoma of the pulvinar.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Cerebral Aqueduct / pathology. Fetal Diseases / pathology. Pulvinar / pathology

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  • (PMID = 15459783.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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38. Wacker A, Will BE, Schöning M, Neunhoeffer F: [Intracerebral bleeding as the first symptom of a congenital anaplastic astrocytoma]. Z Geburtshilfe Neonatol; 2008 Oct;212(5):194-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intracerebral bleeding as the first symptom of a congenital anaplastic astrocytoma].
  • BACKGROUND: Anaplastic astrocytomas in neonates are extremely rare.
  • A CT scan showed cerebral bleeding in the left parieto-occipital region, partially clotted, with a space-demanding effect.
  • No tumour was found, but an anaplastic astrocytoma (WHO Grade III) was diagnosed histologically.
  • CONCLUSION: Congenital anaplastic astrocytomas have a variable outcome, with different survival rates as compared to adults.
  • [MeSH-major] Astrocytoma / congenital. Brain Neoplasms / congenital. Cerebral Hemorrhage / congenital

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  • (PMID = 18956278.001).
  • [ISSN] 0948-2393
  • [Journal-full-title] Zeitschrift für Geburtshilfe und Neonatologie
  • [ISO-abbreviation] Z Geburtshilfe Neonatol
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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39. Wang M, Tihan T, Rojiani AM, Bodhireddy SR, Prayson RA, Iacuone JJ, Alles AJ, Donahue DJ, Hessler RB, Kim JH, Haas M, Rosenblum MK, Burger PC: Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. J Neuropathol Exp Neurol; 2005 Oct;64(10):875-81
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  • [Title] Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma.
  • We present 8 examples of a neoplasm with features of both astrocytoma and ependymoma that may represent a distinct clinicopathologic entity.
  • The cerebral hemispheric tumors occurred in patients that were 3, 4, 12, 14, 15, 26, 30, and 37 years of age.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / complications. Brain Neoplasms / pathology. Ependymoma / pathology. Epilepsy / etiology. Glioma / complications. Glioma / pathology


40. Kumar AJ, Leeds NE, Kumar VA, Fuller GN, Lang FF, Milas Z, Weinberg JS, Ater JL, Sawaya R: Magnetic resonance imaging features of pilocytic astrocytoma of the brain mimicking high-grade gliomas. J Comput Assist Tomogr; 2010 Jul;34(4):601-11
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  • [Title] Magnetic resonance imaging features of pilocytic astrocytoma of the brain mimicking high-grade gliomas.
  • OBJECTIVE: The typical magnetic resonance/computed tomographic imaging appearance of pilocytic astrocytoma (PA) is that of a cyst with an intensely enhancing mural nodule.
  • Tumor locations consisted of the following: optic chiasm (22), lateral ventricle (3), thalamus (12), basal ganglia (1), cerebral hemisphere (10), corpus callosum (2), brain stem (26), fourth ventricle (1), and cerebellum (23).
  • CONCLUSIONS: It is important to recognize the aggressive imaging appearance of PA (grade 1 astrocytoma) because it can be mistaken for high-grade gliomas and may thus lead to inappropriate therapy.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Glioma / diagnosis. Magnetic Resonance Imaging / methods

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  • (PMID = 20657231.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. Schreuder T, Te Lintelo M, Kubat B, Koehler P: Anaplastic oligo-astrocytoma occurring after resection of a cerebral cavernous malformation; malignant transformation? Case report and review on etiology. J Neurol; 2010 Mar;257(3):349-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anaplastic oligo-astrocytoma occurring after resection of a cerebral cavernous malformation; malignant transformation? Case report and review on etiology.
  • We report a 71-year-old woman who presented with a cerebral cavernous malformation in the right frontal lobe for which she underwent total resection.
  • Histological examination showed an anaplastic oligo-astrocytoma.
  • These findings suggest that cerebral cavernous malformations, or at least a subgroup, have the potential for oligodendrocytic and astrocytic transformation.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Hemangioma, Cavernous, Central Nervous System / complications. Hemangioma, Cavernous, Central Nervous System / surgery. Postoperative Complications / pathology


42. Guo XL, Zhong YF, Sun YH, Liu HH, Jin B, Liang W, Li XS: [Muscle atrophy of hand as an initial sign in a patient with protoplasmic astrocytoma: a case report and literature review]. Beijing Da Xue Xue Bao; 2008 Dec 18;40(6):649-51
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  • [Title] [Muscle atrophy of hand as an initial sign in a patient with protoplasmic astrocytoma: a case report and literature review].
  • We reported a rare case of protoplasmic astrocytoma presenting small muscle atrophy of the right hand as an initial sign.
  • CT and MRI revealed multiply expansive intracranial lesion in left hemisphere, which was highly suspected of cerebral echinococcus or Balo disease.
  • The patient underwent surgical excision and pathological report was protoplasmic astrocytoma, with glial fibrillary acidic protein (GFAP, +++) of immunohistochemical method.
  • We reviewed clinical features, radiological manifestations and pathology of protoplasmic astrocytoma with medical literature documents.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Muscular Atrophy / complications

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  • (PMID = 19088841.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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43. Josan V, Smith P, Kornberg A, Rickert C, Maixner W: Development of a pilocytic astrocytoma in a dysembryoplastic neuroepithelial tumor. Case report. J Neurosurg; 2007 Jun;106(6 Suppl):509-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Development of a pilocytic astrocytoma in a dysembryoplastic neuroepithelial tumor. Case report.
  • Dysembryoplastic neuroepithelial tumors (DNETs) are benign supratentorial tumors based in the cerebral cortex.
  • The authors report on a patient in whom a pilocytic astrocytoma developed within a DNET, raising questions regarding the classification of these lesions and the need for lifelong clinical and imaging surveillance.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Cerebral Cortex. Magnetic Resonance Imaging. Neoplasms, Second Primary / diagnosis. Neuroectodermal Tumors, Primitive / diagnosis


44. Schittenhelm J, Psaras T: Glioblastoma with granular cell astrocytoma features: a case report and literature review. Clin Neuropathol; 2010 Sep-Oct;29(5):323-9
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  • [Title] Glioblastoma with granular cell astrocytoma features: a case report and literature review.
  • The resected tumor showed histological features of a glioblastoma with granular cell astrocytoma features, lacking amplification of the EGFR gene region and IDH1R132H mutation.
  • Literature review of 59 cases showed a 12-month overall survival of 11.7% for high-grade and 40% for low-grade granular cell astrocytomas.
  • In 35% more than one cerebral lobe was affected.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Glioblastoma / pathology

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  • (PMID = 20860896.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
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45. Phi JH, Park SH, Chae JH, Hong KH, Park SS, Kang JH, Jun JK, Cho BK, Wang KC, Kim SK: Congenital subependymal giant cell astrocytoma: clinical considerations and expression of radial glial cell markers in giant cells. Childs Nerv Syst; 2008 Dec;24(12):1499-503
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital subependymal giant cell astrocytoma: clinical considerations and expression of radial glial cell markers in giant cells.
  • OBJECTS: Congenital Subependymal giant cell astrocytoma (SEGA), diagnosed in fetal and neonatal period, is extremely rare.
  • [MeSH-major] Astrocytoma / surgery. Cerebral Ventricle Neoplasms / surgery. Fetal Diseases / surgery

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  • (PMID = 18629509.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Carrier Proteins; 0 / FABP7 protein, human; 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin; 0 / SOX2 protein, human; 0 / SOXB1 Transcription Factors; 0 / Tumor Suppressor Proteins; 0 / Vimentin
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46. Hamada H, Kurimoto M, Hayashi N, Nagai S, Kurosaki K, Nomoto K, Kanegane H, Nomura K, Endo S: Pilomyxoid astrocytoma in a patient presenting with fatal hemorrhage. Case report. J Neurosurg Pediatr; 2008 Mar;1(3):244-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pilomyxoid astrocytoma in a patient presenting with fatal hemorrhage. Case report.
  • The authors report on a rare case of pilomyxoid astrocytoma in a patient presenting with fatal hemorrhage.
  • Because the pathological diagnosis was pilomyxoid astrocytoma, chemotherapy was administered.
  • In this report, the authors review the literature and discuss the clinical features and treatment of pilomyxoid astrocytoma.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Cerebral Hemorrhage / diagnosis
  • [MeSH-minor] Cerebral Ventricle Neoplasms / diagnosis. Chemotherapy, Adjuvant. Child, Preschool. Diagnosis, Differential. Fatal Outcome. Humans. Hydrocephalus / diagnosis. Magnetic Resonance Imaging. Male. Third Ventricle / pathology. Tomography, X-Ray Computed

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  • (PMID = 18352771.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 19
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47. Klein O, Grignon Y, Civit T, Pinelli C, Auque J, Marchal JC: [Childhood diencephalic pilocytic astrocytoma. A review of seven observations]. Neurochirurgie; 2006 Feb;52(1):3-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Childhood diencephalic pilocytic astrocytoma. A review of seven observations].
  • [Transliterated title] Les astrocytomes pilocytiques du diencephale de l'enfant. à propos de sept observations.
  • BACKGROUND AND PURPOSE: Pilocytic astrocytoma (PA) is a WHO grade I tumor of the central nervous system mostly arising in children and young adults.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Hypothalamic Neoplasms / surgery. Thalamic Diseases / surgery
  • [MeSH-minor] Adolescent. Chemotherapy, Adjuvant. Child. Child, Preschool. Combined Modality Therapy. Dominance, Cerebral / physiology. Female. Follow-Up Studies. Humans. Hypothalamus / pathology. Hypothalamus / surgery. Infant. Magnetic Resonance Imaging. Male. Quality of Life. Radiotherapy, Adjuvant. Reoperation. Retrospective Studies. Survival Rate. Thalamus / pathology. Thalamus / surgery. Tomography, X-Ray Computed

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  • (PMID = 16609655.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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48. Hafez RF: Stereotaxic gamma knife surgery in treatment of critically located pilocytic astrocytoma: preliminary result. World J Surg Oncol; 2007;5:39
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  • [Title] Stereotaxic gamma knife surgery in treatment of critically located pilocytic astrocytoma: preliminary result.
  • BACKGROUND: Low-grade gliomas are uncommon primary brain tumors, located more often in the posterior fossa, optic pathway, and brain stem and less commonly in the cerebral hemispheres.
  • CASE PRESENTATIONS: Two patients with diagnosed recurrent cystic pilocytic astrocytoma critically located within the brain (thalamic and brain stem) were treated with gamma knife surgery.
  • CONCLUSION: Gamma knife surgery represents an alternate tool in the treatment of recurrent and/or small postoperative residual pilocytic astrocytoma especially if they are critically located.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Radiosurgery

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  • [Cites] J Neurosurg. 2001 Nov;95(5):735-45 [11702861.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 May 1;53(1):43-51 [12007940.001]
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  • [Cites] Neurosurgery. 1996 Apr;38(4):696-701; discussion 701-2 [8692387.001]
  • (PMID = 17394660.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1852107
  • [General-notes] NLM/ Original DateCompleted: 20070726
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49. Bartik P, Maglott A, Entlicher G, Vestweber D, Takeda K, Martin S, Dontenwill M: Detection of a hypersialylated beta1 integrin endogenously expressed in the human astrocytoma cell line A172. Int J Oncol; 2008 May;32(5):1021-31
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  • [Title] Detection of a hypersialylated beta1 integrin endogenously expressed in the human astrocytoma cell line A172.
  • Human cerebral tumors express high level of alpha5beta1 integrins.
  • As a potential new target, alpha5beta1 was investigated here in two human astrocytoma cell lines, A172 and U87MG.
  • [MeSH-major] Antigens, CD29 / metabolism. Astrocytoma / metabolism. Brain Neoplasms / metabolism. Protein Processing, Post-Translational. Sialic Acids / metabolism

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  • (PMID = 18425328.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antigens, CD29; 0 / Fibronectins; 0 / Integrin alpha5; 0 / Integrin alpha5beta1; 0 / Propionates; 0 / Pyridines; 0 / SJ749; 0 / Sialic Acids; 0 / Spiro Compounds
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50. Brat DJ, Scheithauer BW, Fuller GN, Tihan T: Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. Brain Pathol; 2007 Jul;17(3):319-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma.
  • Three new tumours, angiocentric glioma (AG), pilomyxoid astrocytoma (PMA), and pituicytoma are added to the section on gliomas.
  • AG is a slowly growing cerebral tumour that typically presents with seizures in children and young adults.
  • While PMA is considered a more aggressive variant of pilocytic astrocytoma, this relationship awaits further clarification.
  • [MeSH-major] Astrocytoma / classification. Central Nervous System Neoplasms / classification. Glioma / classification. Neuroglia / pathology. Pituitary Gland / pathology. Pituitary Neoplasms / classification. World Health Organization

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  • (PMID = 17598825.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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51. Karami KJ, Poulik J, Rabah R, Krass J, Sood S: Simultaneous choroid plexus carcinoma and pilocytic astrocytoma in a pediatric patient. J Neurosurg Pediatr; 2010 Jan;5(1):104-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Simultaneous choroid plexus carcinoma and pilocytic astrocytoma in a pediatric patient.
  • The authors report the case of a 4-year-old boy with simultaneous choroid plexus carcinoma and pilocytic astrocytoma with features of oligodendroglioma.
  • Upon gross inspection intraoperatively as well as postoperative histological analysis, 2 distinct simultaneous tumors were identified: choroid plexus carcinoma and pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / diagnosis. Astrocytoma / surgery. Cerebral Ventricle Neoplasms / diagnosis. Cerebral Ventricle Neoplasms / surgery. Choroid Plexus Neoplasms / diagnosis. Choroid Plexus Neoplasms / surgery. Fourth Ventricle / surgery. Lateral Ventricles / surgery. Magnetic Resonance Imaging. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / surgery. Neuronavigation. Thalamus / surgery. Tomography, X-Ray Computed


52. Wierzba-Bobrowicz T, Lewandowska E, Matyja E, Dziduszko J, Koszewski W, Stepień T, Błazejewska-Hyzorek B: Granular cell astrocytoma. A case report with immunohistochemical and ultrastructural characterization. Folia Neuropathol; 2008;46(4):286-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell astrocytoma. A case report with immunohistochemical and ultrastructural characterization.
  • Granular cell astrocytoma (GCA) is an uncommon type of granular cell tumours (GCTs) in the central nervous system.
  • We report a case of cerebral GCA in a 59-year-old man who suffered from diabetes and Addison-Biermer disease.

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  • (PMID = 19169970.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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53. Sekula RF Jr, Marchan EM, Quigley MR, Frederickson AM, Pu C: A case of an elderly adult presenting with obstructive hydrocephalus secondary to a rare hemorrhagic suprasellar pilocytic astrocytoma. Clin Neuropathol; 2008 Nov-Dec;27(6):396-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of an elderly adult presenting with obstructive hydrocephalus secondary to a rare hemorrhagic suprasellar pilocytic astrocytoma.
  • Urgent surgery was performed and final pathology eventuated a pilocytic astrocytoma.
  • Although rare cases of suprasellar pilocytic astrocytoma in children and adults have been reported, we report an interesting case of a hemorrhagic suprasellar pilocytic astrocytoma in an elderly adult (without prior anticoagulant use) causing impending brain herniation secondary to obstructive hydrocephalus.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Hemorrhage / etiology. Hydrocephalus / etiology


54. Nicolae L, Iacob G, Poparda M, Popescu BO: Case report. Gelastic seizures in a patient with right gyrus cinguli astrocytoma. J Med Life; 2010 Oct-Dec;3(4):433-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case report. Gelastic seizures in a patient with right gyrus cinguli astrocytoma.
  • II astrocytoma.
  • Diagnosis was made on native CT scan: minimal hypodense frontal right paramedian lesion, cerebral MRI showed a small well delimited right, parenchymal, homogeneous lesion (16/22/15 mm), involving gyrus cinguli, without perilesional edema and mass effect, hyperintense both on T1 and T2 MR sequences, non-enhancing after Gadolinium.
  • The cerebral lesion was also documented on EEG and video-EEG recordings.
  • The anatomopathological analysis revealed a grade II astrocytoma.
  • CONCLUSION: A case of gelastic seizures accompanied by simple motor partial seizures in both arms, without the impairment of his consciousness state induced by a grade II right gyrus cinguli astrocytoma is described and documented by radiological and electrophysiological studies.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Epilepsies, Partial / pathology. Gyrus Cinguli / pathology

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  • [Cites] Neurology. 2001 Dec 26;57(12):2168-78 [11785496.001]
  • [Cites] Epileptic Disord. 1999 Dec;1(4):221-8 [10937157.001]
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  • (PMID = 21254744.001).
  • [ISSN] 1844-122X
  • [Journal-full-title] Journal of medicine and life
  • [ISO-abbreviation] J Med Life
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
  • [Other-IDs] NLM/ PMC3019062
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55. Lin M, Smith T, Beran RG: Crossed cerebellar hyperperfusion on ictal FDG PET in astrocytoma. J Clin Neurosci; 2009 Apr;16(4):603-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Crossed cerebellar hyperperfusion on ictal FDG PET in astrocytoma.
  • Although it is well documented on cerebral single photon emission tomography (SPECT) in patients with epilepsy, it is rarely observed in seizures originating from brain tumours.
  • [MeSH-major] Astrocytoma / radionuclide imaging. Cerebellar Neoplasms / radionuclide imaging. Cerebellum. Cerebrovascular Circulation. Fluorodeoxyglucose F18. Positron-Emission Tomography / methods

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  • (PMID = 19231196.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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56. Jiménez L, Correa-Rivas M, Colón-Castillo L, Rivera-Zengotita M, Colón G, Vigo J, McBurney E: Pilomyxoid astrocytoma in unusual location in a child with neurofibromatosis type 1: case report and review of the literature. P R Health Sci J; 2010 Jun;29(2):123-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pilomyxoid astrocytoma in unusual location in a child with neurofibromatosis type 1: case report and review of the literature.
  • Pilomyxoid astrocytoma (PMA) is a recently defined brain tumor believed to be a variant of pilocytic astrocytoma (PA), but with a more aggressive course.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebral Ventricle Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Neurofibromatosis 1

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  • (PMID = 20496528.001).
  • [ISSN] 0738-0658
  • [Journal-full-title] Puerto Rico health sciences journal
  • [ISO-abbreviation] P R Health Sci J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Puerto Rico
  • [Number-of-references] 27
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57. Takata K, Gasparetto EL, Leite Cda C, Lucato LT, Reed UC, Matushita H, Aguiar PH, Rosemberg S: [Subependymal giant cell astrocytoma in patients with tuberous sclerosis: magnetic resonance imaging findings in ten cases]. Arq Neuropsiquiatr; 2007 Jun;65(2A):313-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Subependymal giant cell astrocytoma in patients with tuberous sclerosis: magnetic resonance imaging findings in ten cases].
  • [Transliterated title] Astrocitoma subependimário de células gigantes em pacientes com esclerose tuberosa: achados em ressonância magnética de dez casos.
  • OBJECTIVE: To report the magnetic resonance imaging (MRI) findings in 10 patients with subependimal giant cell astrocytoma (SGCA) and tuberous sclerosis (TS).
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Ventricles / pathology. Tuberous Sclerosis / pathology


58. Jea A, Coscarella E, Chintagumpala M, Bhattacharjee M, Whitehead WE, Curry DJ, Luerssen TG: Medulloblastoma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors in a child: case report. J Neurosurg Pediatr; 2010 Feb;5(2):149-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Medulloblastoma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors in a child: case report.
  • Pathological examination revealed the left cerebellar and superior vermian lesions to be a juvenile pilocytic astrocytoma and a medulloblastoma, respectively.
  • To the best of the authors' knowledge, they describe the first known pediatric case in which a medulloblastoma and a juvenile pilocytic astrocytoma presented as synchronous primary brain tumors.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebellar Neoplasms / pathology. Medulloblastoma / pathology
  • [MeSH-minor] Cerebral Cortex / pathology. Cerebral Cortex / surgery. Child. Craniotomy. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Tomography, X-Ray Computed


59. Tsutsumi S, Abe Y, Yasumoto Y, Ito M: Anaplastic pleomorphic xanthoastrocytoma with a component of anaplastic astrocytoma presenting as skull base tumor followed by downward extracranial extension. Case report. Neurol Med Chir (Tokyo); 2010;50(12):1108-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anaplastic pleomorphic xanthoastrocytoma with a component of anaplastic astrocytoma presenting as skull base tumor followed by downward extracranial extension. Case report.
  • Most of the tumor was located extraaxially, but a part of the tumor had invaded the temporal lobe, and had tightly adhered to the middle cerebral artery and its perforating vessels.
  • Histological examination revealed cellular pleomorphism with mitotic activity, focal necrosis, but lacking endothelial proliferation, consistent with anaplastic pleomorphic xanthoastrocytoma (PXA) with component of anaplastic astrocytoma.
  • PXA with anaplastic appearance may have a component of anaplastic astrocytoma with more aggressive behavior.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Skull Base Neoplasms / pathology

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  • (PMID = 21206189.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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60. Abel TJ, Chowdhary A, Thapa M, Rutledge JC, Geyer JR, Ojemann J, Avellino AM: Spinal cord pilocytic astrocytoma with leptomeningeal dissemination to the brain. Case report and review of the literature. J Neurosurg; 2006 Dec;105(6 Suppl):508-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal cord pilocytic astrocytoma with leptomeningeal dissemination to the brain. Case report and review of the literature.
  • The authors report a unique case of leptomeningeal dissemination of a spinal cord pilocytic astrocytoma (PCA) to the intracranial cerebral subarachnoid spaces in a child.
  • [MeSH-major] Astrocytoma / secondary. Brain Neoplasms / secondary. Meningeal Neoplasms / secondary. Spinal Cord Neoplasms / pathology


61. Waschbisch A, Fiebich BL, Akundi RS, Schmitz ML, Hoozemans JJ, Candelario-Jalil E, Virtainen N, Veerhuis R, Slawik H, Yrjänheikki J, Hüll M: Interleukin-1 beta-induced expression of the prostaglandin E-receptor subtype EP3 in U373 astrocytoma cells depends on protein kinase C and nuclear factor-kappaB. J Neurochem; 2006 Feb;96(3):680-93
Gene Ontology. gene/protein/disease-specific - Gene Ontology annotations from this paper .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Interleukin-1 beta-induced expression of the prostaglandin E-receptor subtype EP3 in U373 astrocytoma cells depends on protein kinase C and nuclear factor-kappaB.
  • Here we describe IL-1beta-induced EP3 receptor expression in human astrocytoma cells, primary astrocytes of rat and human origin and in rat brain.
  • This might play an important role in acute and chronic conditions such as cerebral ischemia, traumatic brain injury, HIV-encephalitis, Alzheimer's disease and prion diseases in which a marked up-regulation of IL-1beta is followed by a prolonged increase of PGE2 levels in the brain.
  • [MeSH-major] Astrocytoma / metabolism. Gene Expression Regulation, Neoplastic / drug effects. Interleukin-1 / pharmacology. NF-kappa B / physiology. Protein Kinase C / physiology. Receptors, Prostaglandin E / metabolism

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  • (PMID = 16405508.001).
  • [ISSN] 0022-3042
  • [Journal-full-title] Journal of neurochemistry
  • [ISO-abbreviation] J. Neurochem.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Interleukin-1; 0 / NF-kappa B; 0 / PTGER3 protein, human; 0 / Ptger3 protein, rat; 0 / RNA, Messenger; 0 / Receptors, Prostaglandin E; 0 / Receptors, Prostaglandin E, EP3 Subtype; EC 2.7.11.13 / Protein Kinase C
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62. Bing F, Kremer S, Lamalle L, Chabardes S, Ashraf A, Pasquier B, Le Bas JF, Krainik A, Grand S: [Value of perfusion MRI in the study of pilocytic astrocytoma and hemangioblastoma: preliminary findings]. J Neuroradiol; 2009 May;36(2):82-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Value of perfusion MRI in the study of pilocytic astrocytoma and hemangioblastoma: preliminary findings].
  • PURPOSE: Pilocytic astrocytomas (PA) and hemangioblastomas (HB) can present the same morphological characteristics on conventional MRI sequences, most usually in the form of a cerebellar cystic mass with a mural nodule that strongly enhances on post-contrast T1 images.
  • The maximum relative cerebral blood volume (rCBV(max)), defined as the ratio between the CBV(max) in tumor tissue and the CBV in healthy, contralateral white matter, is considered to be indicative of the type of tumor.
  • [MeSH-major] Astrocytoma / diagnosis. Blood Volume. Brain / blood supply. Brain Neoplasms / diagnosis. Cerebrovascular Circulation. Hemangioblastoma / diagnosis. Magnetic Resonance Imaging / methods


63. Osoba AO, Kutub H, Waliuddin A, Sharab MO: Enterococcus avium. An unusual cause of cerebral abscess. Neurosciences (Riyadh); 2005 Oct;10(4):297-300

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Enterococcus avium. An unusual cause of cerebral abscess.
  • Here, we report a 19-year-old Saudi girl diagnosed as a case of astrocytoma grade II arising from the right thalamus.
  • She subsequently developed a cerebral abscess, and we performed mini craniotomy of the left parietal region with drainage of the brain abscess.
  • The rarity of the organism causing cerebral abscess has motivated the documentation of this case and the pathogenesis of Enterococcus avium.

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  • (PMID = 22473142.001).
  • [ISSN] 1319-6138
  • [Journal-full-title] Neurosciences (Riyadh, Saudi Arabia)
  • [ISO-abbreviation] Neurosciences (Riyadh)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
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64. Maciá Escalante S, Rodríguez Lescure A, Segura Ibáñez JM, Sáez Castán J, Guillén Ponce C, Carrato Mena A: Patient with resected anaplastic astrocytoma and an image suggestive of relapse. Clin Transl Oncol; 2006 Dec;8(12):912-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Patient with resected anaplastic astrocytoma and an image suggestive of relapse.
  • With respect to the cerebral edema that can be associated with the carmustine implants, there can appear images in follow-up that are suggestive of relapse.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Edema / radiography. Brain Neoplasms / diagnosis. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 17169765.001).
  • [ISSN] 1699-048X
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Decanoic Acids; 0 / Polyesters; 90409-78-2 / decanedioic acid-4,4'-(1,3-propanediylbis(oxy))bis(benzoic acid) copolymer; U68WG3173Y / Carmustine
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65. Kim SJ, Jeong HJ, Kim BK, Kim NH, Kim JS, Choi KS, Lee HJ, Kang ST, Shin SS, Kim WI, Eom HS, Lee KM, Um JY, Hong SH, Kim HM: Anti-inflammatory effect of jeongshintang through suppression of p38 activation in human astrocytoma, U373MG cells. Exp Mol Pathol; 2006 Aug;81(1):85-91
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anti-inflammatory effect of jeongshintang through suppression of p38 activation in human astrocytoma, U373MG cells.
  • Jeongshintang (JST) is a Korean herbal prescription, which has been successfully used for cerebral diseases.
  • [MeSH-minor] Amyloid beta-Peptides / toxicity. Astrocytoma. Cell Line, Tumor. Cyclooxygenase 2. Dinoprostone / antagonists & inhibitors. Enzyme Activation / drug effects. Humans. Interleukin-1 / toxicity. Interleukin-6 / antagonists & inhibitors. Interleukin-8 / antagonists & inhibitors. Membrane Proteins / antagonists & inhibitors. Peptide Fragments / toxicity. Protein Kinase Inhibitors / pharmacology

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  • (PMID = 16698013.001).
  • [ISSN] 0014-4800
  • [Journal-full-title] Experimental and molecular pathology
  • [ISO-abbreviation] Exp. Mol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amyloid beta-Peptides; 0 / Anti-Inflammatory Agents; 0 / Interleukin-1; 0 / Interleukin-6; 0 / Interleukin-8; 0 / Membrane Proteins; 0 / Neuroprotective Agents; 0 / Peptide Fragments; 0 / Plant Extracts; 0 / Protein Kinase Inhibitors; 0 / amyloid beta-protein (1-42); 0 / jeongshintang; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases; K7Q1JQR04M / Dinoprostone
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66. Lee D, Suh YL, Nam DH: Cerebral granular cell tumor. Neuropathology; 2008 Aug;28(4):417-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebral granular cell tumor.
  • We report here on a case of cerebral GCT in a 47-year-old man who suffered with severe headache.
  • These wide immunoexpressions were not observed for the previously reported cerebral GCTs.
  • Despite these wide immunoexpressions and the lack of any association with astrocytoma, the histogenesis of cerebral GCTs is still suggested to be of a glial origin, based on the tumor location, the GFAP positivity and the ultrastructural findings, of which the latter showed intermediate filaments, and these are reminiscent of neoplastic astrocytes.
  • [MeSH-minor] Astrocytoma / pathology. Diagnosis, Differential. Glial Fibrillary Acidic Protein / metabolism. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged

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  • (PMID = 18466222.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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67. White JB, Piepgras DG, Scheithauer BW, Parisi JE: Rate of spontaneous hemorrhage in histologically proven cases of pilocytic astrocytoma. J Neurosurg; 2008 Feb;108(2):223-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rate of spontaneous hemorrhage in histologically proven cases of pilocytic astrocytoma.
  • Hemorrhage in primary gliomas occurs in 3.7-7.2% of gliomas, mainly in glioblastoma muliforme and oligodendroglioma with low-grade astrocytomas accounting for <1%.
  • Hemorrhage associated with pilocytic astrocytomas (PAs) is only sporadically reported.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Cerebral Hemorrhage / etiology


68. Kartashev AV, Vinogradov VM, Oliushin VE, Gerasimov SV: [Accelerated postoperative chemoradiotherapy for malignant cerebral glioma]. Vopr Onkol; 2008;54(1):102-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Accelerated postoperative chemoradiotherapy for malignant cerebral glioma].
  • Procedure of accelerated immunotherapy for cerebral glioma is presented.
  • [MeSH-minor] Adult. Aged. Astrocytoma / therapy. Chemotherapy, Adjuvant. Dose Fractionation. Female. Glioblastoma / therapy. Humans. Male. Middle Aged. Nitrosourea Compounds / administration & dosage. Postoperative Period. Radiotherapy, Adjuvant. Recombinant Proteins. Survival Analysis. Time Factors. Treatment Outcome. Vincristine / administration & dosage

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  • (PMID = 18416069.001).
  • [ISSN] 0507-3758
  • [Journal-full-title] Voprosy onkologii
  • [ISO-abbreviation] Vopr Onkol
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Immunologic Factors; 0 / Nitrosourea Compounds; 0 / Recombinant Proteins; 123774-72-1 / sargramostim; 5J49Q6B70F / Vincristine; 83869-56-1 / Granulocyte-Macrophage Colony-Stimulating Factor
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69. Daglioglu E, Ergungor F, Hatipoglu HG, Okay O, Dalgic A, Orhan G, Unal T: Cerebral leukoencephalopathy with calcifications and cysts operated for signs of increased intracranial pressure: case report. Surg Neurol; 2009 Aug;72(2):177-81
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  • [Title] Cerebral leukoencephalopathy with calcifications and cysts operated for signs of increased intracranial pressure: case report.
  • It should be differentiated from FD or bilateral striopallidodentate calcinosis and astrocytoma.
  • Yet, there are many other clinical syndromes featuring bilateral symmetric cerebral calcifications.
  • The patient had symmetric bilateral cerebral and cerebellar calcifications, white matter edema, and a secondary thalamic cyst as well.
  • CONCLUSION: Patients with findings of cystic cerebral calcifications on CT scans should be followed cautiously for acute deterioration because surgery is indicated in cases having signs of increased intracranial pressure.

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  • (PMID = 18514290.001).
  • [ISSN] 1879-3339
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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70. Kim TW, Lee TK, Kim BS, Lee KS, Song IU, Kim JS: Diurnally fluctuating frontal dysequilibrium secondary to a pineal pilocytic astrocytoma: is this symptom associated with a check-valve mechanism in a pineal region tumor? Childs Nerv Syst; 2009 Mar;25(3):367-71
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  • [Title] Diurnally fluctuating frontal dysequilibrium secondary to a pineal pilocytic astrocytoma: is this symptom associated with a check-valve mechanism in a pineal region tumor?
  • CASE REPORT: A 14-year-old boy presented with diurnally fluctuating dysarthria, dysequilibrium of the gait, and retropulsion, probably due to transient obstruction by a tumor at the entrance of the cerebral aqueduct of the pineal region.
  • [MeSH-major] Astrocytoma / complications. Hydrocephalus / etiology. Hydrocephalus / physiopathology. Pineal Gland / pathology. Pinealoma / complications. Supratentorial Neoplasms / complications

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  • (PMID = 18972117.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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71. Wei CW, Guo G, Mikulis DJ: Tumor effects on cerebral white matter as characterized by diffusion tensor tractography. Can J Neurol Sci; 2007 Feb;34(1):62-8
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  • [Title] Tumor effects on cerebral white matter as characterized by diffusion tensor tractography.
  • In cerebral neoplasm, DTT can be used to illustrate the relationship of the tumor with respect to adjacent WM trajectories.
  • METHODS: Fiber tractography was used in this study to assess tumor-induced changes in WM trajectories in three cases of cerebral neoplasm: glioblastoma multiforme, meningioma, and anaplastic astrocytoma.
  • In anaplastic astrocytoma, fiber tracking demonstrated disruption of WM tracts at the tumor origin as well as intact axons through areas of tumor infiltration.
  • [MeSH-minor] Aged. Astrocytoma / diagnosis. Astrocytoma / physiopathology. Brain Mapping / methods. Corpus Callosum / pathology. Corpus Callosum / physiopathology. Disease Progression. Female. Glioblastoma / diagnosis. Glioblastoma / physiopathology. Humans. Image Processing, Computer-Assisted / methods. Magnetic Resonance Imaging / trends. Male. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / physiopathology. Meningioma / diagnosis. Meningioma / physiopathology. Middle Aged. Neoplasm Invasiveness. Predictive Value of Tests. Preoperative Care / methods. Preoperative Care / trends. Pyramidal Tracts / pathology. Pyramidal Tracts / physiopathology

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  • (PMID = 17352349.001).
  • [ISSN] 0317-1671
  • [Journal-full-title] The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • [ISO-abbreviation] Can J Neurol Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
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72. Ghauri AJ, Musadiq M, Sha Y, Elsherbiny S: Late onset of subfoveal choroidal neovascularisation following cerebral radiotherapy. BMJ Case Rep; 2010;2010
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  • [Title] Late onset of subfoveal choroidal neovascularisation following cerebral radiotherapy.
  • A 43-year-old Caucasian man presented with a 4-week history of sudden loss of central vision in the left eye, 8.5 years following radical radiotherapy for left tempero-parietal anaplastic astrocytoma.
  • Radiation retinopathy associated CNV is a late ocular complication of cerebral radiotherapy.
  • It should be investigated as a possible aetiology of severe visual loss in long-term survivors of cerebral tumours who have previously received radiotherapy.
  • [MeSH-major] Astrocytoma / radiotherapy. Brain Neoplasms / radiotherapy. Choroidal Neovascularization / etiology

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73. Lemire J, Mailloux RJ, Appanna VD: Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1). PLoS One; 2008;3(2):e1550
Hazardous Substances Data Bank. LACTIC ACID .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1).
  • Lactate has long been regarded as an end product of anaerobic energy production and its fate in cerebral metabolism has not been precisely delineated.
  • [MeSH-major] Astrocytoma / metabolism. L-Lactate Dehydrogenase / metabolism. Mitochondrial Proteins / metabolism. Oxidative Phosphorylation

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  • (PMID = 18253497.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mitochondrial Proteins; 33X04XA5AT / Lactic Acid; 8L70Q75FXE / Adenosine Triphosphate; EC 1.1.1.27 / L-Lactate Dehydrogenase
  • [Other-IDs] NLM/ PMC2212712
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74. Perez-Saldana MT, Vilar C, Geffner-Sclarsky D, Belenguer-Benavides A, Del Villar-Igea A, Gil-Fortuno M, Bahamonde D: [Meningoencephalomyelitis as the initial symptom of a brain tumour mimicking encephalitis due to herpes simplex virus: a case report]. Rev Neurol; 2007 Mar 16-31;44(6):348-52
MedlinePlus Health Information. consumer health - Meningitis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Meningoencefalomielitis como manifestacion inicial de un tumor cerebral que imita una encefalitis por virus del herpes simple: descripcion de un caso.
  • The post-mortem examination revealed a grade III oligoastrocytoma in both temporal lobes, which had extended into the adjacent subarachnoid space and the cerebral and cervical leptomeninges.
  • [MeSH-major] Astrocytoma. Brain Neoplasms. Encephalitis, Herpes Simplex / etiology. Meninges / pathology. Meningitis / etiology

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  • (PMID = 17385171.001).
  • [ISSN] 0210-0010
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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75. Hu WW, Zheng XJ, Shen G, Liu WG, Shen H, Fu WM, Zhou JY: [Diagnosis and micro-neurosurgery for the fourth cerebral ventricle tumors]. Zhonghua Zhong Liu Za Zhi; 2007 Feb;29(2):144-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis and micro-neurosurgery for the fourth cerebral ventricle tumors].
  • OBJECTIVE: To investigate the diagnostic method and analyze the result of microneurosurgical treatment for tumors of the fourth cerebral ventricle.
  • The pathology included 32 medulloblastomas, 23 ependymoma, 15 astrocytoma, 10 hemangiblastomas, 2 choroid plexus papillomas, and 4 epidermoid cysts.
  • CONCLUSION: Medulloblastoma, astrocytoma and hemangiblastoma are suggested to be removed totally whenever technically possible according to the site, character and volume of the tumor.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Fourth Ventricle / pathology. Medulloblastoma / diagnosis. Microsurgery / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Astrocytoma / diagnosis. Astrocytoma / radiography. Astrocytoma / surgery. Child. Child, Preschool. Combined Modality Therapy. Ependymoma / diagnosis. Ependymoma / radiography. Ependymoma / surgery. Female. Follow-Up Studies. Hemangioblastoma / diagnosis. Hemangioblastoma / radiography. Hemangioblastoma / surgery. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Survival Analysis. Survival Rate. Tomography, X-Ray Computed

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  • (PMID = 17645855.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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76. Iun'pén V, Oliushin VE, Ulitin AIu, Maslova LN, Petrov AA: [Long-term results of treatment in patients with oligodendrogliomas and oligoastrocytomas of the cerebral hemispheres]. Zh Vopr Neirokhir Im N N Burdenko; 2008 Apr-Jun;(2):6-10; discussion 10-1
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  • [Title] [Long-term results of treatment in patients with oligodendrogliomas and oligoastrocytomas of the cerebral hemispheres].
  • BACKGROUND: the current approach to treating patients with cerebral oligodendrogliomas and oligoastrocytomas involves surgical treatment with the maximum tumor resection in reasonable ranges, by taking into account the anatomic and physiological availability, followed by chemo- and radiotherapy.
  • [MeSH-major] Astrocytoma / therapy. Brain Neoplasms / therapy. Oligodendroglioma / therapy

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  • (PMID = 18720725.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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77. Walmsley GL, Chandler K, Davies ES, Lamb CR, Smyth B, Summers BA: Multi-focal cerebral oligoastrocytoma in a puppy. J Small Anim Pract; 2009 Aug;50(8):435-9
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  • [Title] Multi-focal cerebral oligoastrocytoma in a puppy.
  • Magnetic resonance imaging identified multiple, large lesions involving both cerebral hemispheres.
  • [MeSH-major] Astrocytoma / veterinary. Brain Neoplasms / veterinary. Neoplasms, Multiple Primary / veterinary

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  • (PMID = 19689673.001).
  • [ISSN] 1748-5827
  • [Journal-full-title] The Journal of small animal practice
  • [ISO-abbreviation] J Small Anim Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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78. Raab P, Hattingen E, Franz K, Zanella FE, Lanfermann H: Cerebral gliomas: diffusional kurtosis imaging analysis of microstructural differences. Radiology; 2010 Mar;254(3):876-81
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebral gliomas: diffusional kurtosis imaging analysis of microstructural differences.
  • PURPOSE: To characterize the non-Gaussian diffusion patterns of cerebral glioma microstructure with respect to the different glioma grades by using a new method called diffusional kurtosis (DK) imaging.
  • RESULTS: In 34 patients with cerebral gliomas (five World Health Organization [WHO] grade II astrocytomas, 13 WHO grade III astrocytomas, and 16 WHO grade IV glioblastomas multiforme), significantly different diffusion patterns were found among the three glioma groups.
  • Significant differences between astrocytoma grades WHO II and WHO III were demonstrated only by DK values.

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  • (PMID = 20089718.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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79. Ferroir JP, Marro B, Belkacemi Y, Stilhart B, Schlienger M: [Cerebral infarction related to intracranial radiation arteritis twenty-four years after encephalic radiation therapy]. Rev Neurol (Paris); 2007 Jan;163(1):96-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cerebral infarction related to intracranial radiation arteritis twenty-four years after encephalic radiation therapy].
  • We report a case of a resolutive late cerebral ischemic event, related to radiation induced vasculopathy of the left posterior cerebral artery, documented by MRI, situated in the irradiated volume 24 years before, for an astrocytome with malignant potential.
  • [MeSH-major] Arteritis / complications. Cerebral Arteries / radiation effects. Cerebral Infarction / etiology
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / radiotherapy. Brain Neoplasms / radiotherapy. Humans. Male. Radiotherapy / adverse effects. Time Factors

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  • (PMID = 17304179.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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80. Revert Ventura AJ, Sanz-Requena R, Martí-Bonmatí L, Jornet J, Piquer J, Cremades A, Carot JM: [Nosological analysis of MRI tissue perfusion parameters obtained using the unicompartmental and pharmacokinetic models in cerebral glioblastomas]. Radiologia; 2010 Sep-Oct;52(5):432-41
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  • [Title] [Nosological analysis of MRI tissue perfusion parameters obtained using the unicompartmental and pharmacokinetic models in cerebral glioblastomas].
  • OBJECTIVES: To classify the tumor areas in patients with grade IV astrocytoma by calculating and statistically analyzing quantitative MRI perfusion parameters.
  • MATERIAL AND METHODS: We applied two models of MRI perfusion, the unicompartmental and the pharmacokinetic models, in 15 patients diagnosed with grade IV astrocytoma.
  • In the unicompartmental model, we quantified cerebral blood volume (CBV), mean transit time (MTT), and cerebral blood flow (CBF).

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  • [Copyright] Copyright © 2009 SERAM. Published by Elsevier Espana. All rights reserved.
  • (PMID = 20655078.001).
  • [ISSN] 0033-8338
  • [Journal-full-title] Radiología
  • [ISO-abbreviation] Radiologia
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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81. Jung CS, Foerch C, Schänzer A, Heck A, Plate KH, Seifert V, Steinmetz H, Raabe A, Sitzer M: Serum GFAP is a diagnostic marker for glioblastoma multiforme. Brain; 2007 Dec;130(Pt 12):3336-41
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A serum marker for malignant cerebral astrocytomas could improve both differential diagnosis and clinical management of brain tumour patients.
  • To evaluate whether the serum concentration of glial fibrillary acidic protein (GFAP) may indicate glioblastoma multiforme (GBM) in patients with single supratentorial space-occupying lesions, we prospectively examined 50 consecutive patients with histologically proven GBM, World Health Organization (WHO) grade IV, 14 patients with anaplastic astrocytoma (WHO grade III), 4 patients with anaplastic oligodendroglioma, 13 patients with diffuse astrocytoma (WHO grade II), 17 patients with a single cerebral metastasis and 50 healthy controls.

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  • (PMID = 17998256.001).
  • [ISSN] 1460-2156
  • [Journal-full-title] Brain : a journal of neurology
  • [ISO-abbreviation] Brain
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Neoplasm Proteins
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82. Pascual-Castroviejo I, Pascual-Pascual SI, Viaño J, Velázquez-Fragua R, Carceller-Benito F, Gutiérrez-Molina M, Morales-Bastos C: [Cerebral hemisphere tumours in neurofibromatosis type 1 during childhood]. Rev Neurol; 2010 Apr 16;50(8):453-7
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  • [Title] [Cerebral hemisphere tumours in neurofibromatosis type 1 during childhood].
  • AIM: To present seven tumors of the cerebral hemispheres in 6 children with neurofibromatosis type 1 (NF1).
  • PATIENTS AND METHODS: Six patients (three males and three females) of 600 cases of a series with NF1 showed features of cerebral hemispheres tumor (seizures, headache and hemiparesis).
  • The histological study was made to the other five patients and showed that the histological nature corresponded to pilocytic astrocytoma in one patient, neuroepitelial dysembryoplastic tumor in one, polymorphe xanthoastrocytoma in one, neuroectodermic hamartoma in one, and inflammatory chronic non-granulomatose lesion in one.
  • CONCLUSION: The prevalence of the tumors in the cerebral hemispheres is very low (1%) in the patients with NF1.
  • The tumors commonly are histologically benign, and they can be found in peripheral or deep region of the cerebral hemispheres.
  • [MeSH-major] Brain Neoplasms / pathology. Cerebral Cortex / pathology. Neurofibromatosis 1 / pathology


83. Novillo López ME, Gómez-Ibáñez A, Rosenfeld M, Dalmau J: [Gliomatosis cerebri: review of 22 patients]. Neurologia; 2010 Apr;25(3):168-73
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  • [Transliterated title] Gliomatosis cerebral: estudio de 22 pacientes.
  • The most frequent pathological findings were grade III astrocytoma (36.4%), grade II astrocytoma (22.7%), and grade IV astrocytoma (18.3%).

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  • [Copyright] Published by Elservier España, S.L. All rights reserved.
  • (PMID = 20492863.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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84. Calli C, Kitis O, Yunten N, Yurtseven T, Islekel S, Akalin T: Perfusion and diffusion MR imaging in enhancing malignant cerebral tumors. Eur J Radiol; 2006 Jun;58(3):394-403
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  • [Title] Perfusion and diffusion MR imaging in enhancing malignant cerebral tumors.
  • OBJECTIVE: Common contrast-enhancing malignant tumors of the brain are glioblastoma multiforme (GBMs), anaplastic astrocytomas (AAs), metastases, and lymphomas, all of which have sometimes similar conventional MRI findings.
  • Our aim was to evaluate the role of perfusion MR imaging (PWI) and diffusion-weighted imaging (DWI) in the differentiation of these contrast-enhancing malignant cerebral tumors.
  • PWI was applied using dynamic susceptibility contrast technique and maximum relative cerebral blood volume (rCBV(max)) was calculated from each tumor, given in ratio with contralateral normal white matter.
  • CONCLUSION: Combination of DWI and PWI, with ADC(min) and rCBV(max) calculations, may aid routine MR imaging in the differentiation of common cerebral contrast-enhancing malignant tumors.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging / methods. Glioblastoma / diagnosis. Image Enhancement / methods. Lymphoma / diagnosis. Magnetic Resonance Angiography / methods

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  • (PMID = 16527438.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media
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85. Di Costanzo A, Pollice S, Trojsi F, Giannatempo GM, Popolizio T, Canalis L, Armillotta M, Maggialetti A, Carriero A, Tedeschi G, Scarabino T: Role of perfusion-weighted imaging at 3 Tesla in the assessment of malignancy of cerebral gliomas. Radiol Med; 2008 Feb;113(1):134-43
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  • [Title] Role of perfusion-weighted imaging at 3 Tesla in the assessment of malignancy of cerebral gliomas.
  • PWI was performed by first-pass gadopentetate dimeglumine T2*-weighted echo-planar images, and cerebral blood volume (CBV) maps were computed with a nondiffusible tracer model.
  • It enhances the magnetic resonance (MR) assessment of cerebral gliomas and provides useful information for planning surgical and radiation treatment.
  • [MeSH-minor] Adult. Aged. Astrocytoma / diagnosis. Blood Volume / physiology. Brain Edema / diagnosis. Cerebrovascular Circulation / physiology. Contrast Media. Diagnosis, Differential. Echo-Planar Imaging / methods. Female. Gadolinium DTPA. Ganglioglioma / diagnosis. Glioblastoma / diagnosis. Humans. Image Enhancement / methods. Male. Middle Aged. Necrosis. Oligodendroglioma / diagnosis. Retrospective Studies

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  • (PMID = 18338133.001).
  • [ISSN] 0033-8362
  • [Journal-full-title] La Radiologia medica
  • [ISO-abbreviation] Radiol Med
  • [Language] eng; ita
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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86. Jiménez R, Casado-Flores J, Nieto M, García-Teresa MA: Cerebral salt wasting syndrome in children with acute central nervous system injury. Pediatr Neurol; 2006 Oct;35(4):261-3
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  • [Title] Cerebral salt wasting syndrome in children with acute central nervous system injury.
  • The purpose of this investigation was to describe the causes, clinical pattern, and treatment of cerebral salt wasting syndrome in children with acute central nervous system injury.
  • This retrospective study focused on patients<or=15 years old diagnosed with cerebral salt wasting syndrome, over a period of 7 years, in the pediatric intensive care unit of a tertiary care hospital.
  • Fourteen patients were identified with cerebral salt wasting syndrome, 12 after a neurosurgical procedure (8 brain tumor, 4 hydrocephalus) and 2 after severe brain trauma.
  • In 11 patients the cerebral salt wasting syndrome was diagnosed during the first 48 hours of admission.
  • Prevalence of cerebral salt wasting syndrome in neurosurgical children was 11.3/1000 surgical procedures.
  • The mean duration of cerebral salt wasting syndrome was 6+/-5 days (range 1-9).
  • In conclusion, cerebral salt wasting syndrome can complicate the postoperative course of children with brain injury; it is frequently present after surgery for brain tumors and hydrocephalus and in patients with severe head trauma.
  • [MeSH-major] Astrocytoma / surgery. Brain Injuries / surgery. Brain Neoplasms / surgery. Choroid Plexus Neoplasms / surgery. Craniopharyngioma / surgery. Hydrocephalus / surgery. Hyponatremia / diagnosis. Inappropriate ADH Syndrome / diagnosis. Pituitary Neoplasms / surgery. Postoperative Complications / diagnosis


87. Felsberg J, Wolter M, Seul H, Friedensdorf B, Göppert M, Sabel MC, Reifenberger G: Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing. Acta Neuropathol; 2010 Apr;119(4):501-7
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  • [Title] Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing.
  • Diffusely infiltrating cerebral gliomas frequently carry point mutations in codon 132 of the isocitrate dehydrogenase 1 (IDH1) gene or in codon 172 of the IDH2 gene, which are both clinically important as diagnostic and prognostic markers.
  • [MeSH-major] Astrocytoma / genetics. Brain Neoplasms / genetics. DNA Mutational Analysis / methods. Isocitrate Dehydrogenase / genetics. Mutation. Oligodendroglioma / genetics

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  • (PMID = 20131059.001).
  • [ISSN] 1432-0533
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 1.1.1.41 / Isocitrate Dehydrogenase; EC 1.1.1.41 / isocitrate dehydrogenase 2, human; EC 1.1.1.42. / IDH1 protein, human
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88. Holveck A, Grand S, Boini S, Kirchin M, Le Bas JF, Dietemann JL, Bracard S, Kremer S: Dynamic susceptibility contrast-enhanced MRI evaluation of cerebral intraventricular tumors: preliminary results. J Neuroradiol; 2010 Dec;37(5):269-75
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  • [Title] Dynamic susceptibility contrast-enhanced MRI evaluation of cerebral intraventricular tumors: preliminary results.
  • METHODS: A total of 28 patients with intraventricular tumors (five meningiomas, five papillomas, three ependymomas, four subependymomas, seven central neurocytomas, two subependymal giant cell astrocytomas and two metastases) underwent conventional and dynamic susceptibility contrast-enhanced MRI.
  • Cerebral blood volume (CBV) maps were obtained and the relative CBV (rCBV) calculated for each tumor.
  • CONCLUSION: Susceptibility contrast-enhanced MRI can provide additional information on the vascularization of intraventricular cerebral tumors and may help in making the differential diagnosis.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology. Ependymoma / pathology. Magnetic Resonance Imaging / methods. Meningioma / pathology. Neurocytoma / pathology. Papilloma / pathology

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20435349.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
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89. Nariai T, Ishiwata K, Kimura Y, Inaji M, Momose T, Yamamoto T, Matsumura A, Ishii K, Ohno K: PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma. Appl Radiat Isot; 2009 Jul;67(7-8 Suppl):S348-50
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  • [Title] PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma.
  • INTRODUCTION: To plan the optimal BNCT for patients with malignant cerebral glioma, estimation of the ratio of boron concentration in tumor tissue against that in the surrounding normal brain (T/N ratio of boron) is important.
  • METHODS: Twelve patients with cerebral malignant glioma underwent 60 min dynamic PET scanning of brain after bolus injection of (18)F-borono-phenyl-alanine (FBPA) with timed arterial blood sampling.
  • [MeSH-minor] Algorithms. Astrocytoma / metabolism. Astrocytoma / radionuclide imaging. Astrocytoma / radiotherapy. Boron / pharmacokinetics. Boron / therapeutic use. Boron Compounds. Carbon Radioisotopes. Glioblastoma / metabolism. Glioblastoma / radionuclide imaging. Glioblastoma / radiotherapy. Humans. Methionine. Phenylalanine / analogs & derivatives. Radiation-Sensitizing Agents / pharmacokinetics. Radiation-Sensitizing Agents / therapeutic use. Radiotherapy Planning, Computer-Assisted / statistics & numerical data

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  • (PMID = 19375930.001).
  • [ISSN] 1872-9800
  • [Journal-full-title] Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
  • [ISO-abbreviation] Appl Radiat Isot
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Boron Compounds; 0 / Carbon Radioisotopes; 0 / Radiation-Sensitizing Agents; 133921-60-5 / 4-borono-2-fluorophenylalanine; 47E5O17Y3R / Phenylalanine; AE28F7PNPL / Methionine; N9E3X5056Q / Boron
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90. Julow J, Szeifert GT, Bálint K, Nyáry I, Nemes Z: Tissue response to iodine-125 interstitial brachytherapy of cerebral gliomas. Prog Neurol Surg; 2007;20:312-23
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  • [Title] Tissue response to iodine-125 interstitial brachytherapy of cerebral gliomas.
  • The purpose of this study was to investigate histopathological changes and the role of the microglia/macrophage cell system in the therapeutic effect of iodine-125 (125I) interstitial brachytherapy on cerebral gliomas.
  • Out of a series of 60 cases harboring cerebral astrocytomas and other brain tumors treated with 125I interstitial brachytherapy, autopsy material was available in 10 cases between 0.75 and 60 months after irradiation.

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  • (PMID = 17318000.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Iodine Radioisotopes
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91. Katisko JP, Yrjänä SK, Tuominen J, Kokkonen SM, Ilkko E, Erkkilä J, Shiffbauer H, Koivukangas JP: Cerebral edema attenuated inversion recovery MR sequence in low magnetic field: a feasibility study. Acad Radiol; 2006 Feb;13(2):219-28
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  • [Title] Cerebral edema attenuated inversion recovery MR sequence in low magnetic field: a feasibility study.
  • This study investigated technical possibilities and clinical usefulness of adapting edema attenuated inversion recovery (EDAIR) pulse sequences to suppress magnetic resonance signal from cerebral edema in brain tumor patients.
  • [MeSH-minor] Adolescent. Adult. Aged. Astrocytoma / complications. Astrocytoma / pathology. Astrocytoma / surgery. Brain Neoplasms / complications. Brain Neoplasms / pathology. Brain Neoplasms / surgery. Child. Diagnosis, Differential. Feasibility Studies. Female. Humans. Image Enhancement. Intraoperative Care. Male. Middle Aged. Neuroectodermal Tumors, Primitive / complications. Neuroectodermal Tumors, Primitive / pathology. Neuroectodermal Tumors, Primitive / surgery. Neuronavigation. Neurosurgical Procedures. Postoperative Care. Signal Processing, Computer-Assisted

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  • (PMID = 16428058.001).
  • [ISSN] 1076-6332
  • [Journal-full-title] Academic radiology
  • [ISO-abbreviation] Acad Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Bisdas S, Kirkpatrick M, Giglio P, Welsh C, Spampinato MV, Rumboldt Z: Cerebral blood volume measurements by perfusion-weighted MR imaging in gliomas: ready for prime time in predicting short-term outcome and recurrent disease? AJNR Am J Neuroradiol; 2009 Apr;30(4):681-8
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  • [Title] Cerebral blood volume measurements by perfusion-weighted MR imaging in gliomas: ready for prime time in predicting short-term outcome and recurrent disease?
  • Our aim was to determine whether the relative cerebral volume (rCBV) measurements in gliomas may serve as an adjunct to histopathologic grading, with a hypothesis that rCBV values are more accurate in predicting 1-year survival and recurrence.
  • MATERIALS AND METHODS: Thirty-four patients with gliomas (WHO grade I-IV, 27 astrocytomas, 7 tumors with oligodendroglial components) underwent contrast-enhanced MR rCBV measurements before treatment.
  • The rCBV(mean) and rCBV(max) in the astrocytomas were 3.5 +/- 2.9 and 3.7 +/- 2.7.
  • CONCLUSIONS: rCBV values in astrocytomas but not tumors with oligodendroglial components are predictive for recurrence and 1-year survival and may be more accurate than histopathologic grading.
  • [MeSH-major] Astrocytoma / pathology. Blood Volume. Brain Neoplasms / pathology. Cerebrovascular Circulation. Magnetic Resonance Imaging / methods. Oligodendroglioma / pathology

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  • (PMID = 19179427.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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93. Jacques TS, Eldridge C, Patel A, Saleem NM, Powell M, Kitchen ND, Thom M, Revesz T: Mixed glioneuronal tumour of the fourth ventricle with prominent rosette formation. Neuropathol Appl Neurobiol; 2006 Apr;32(2):217-20
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  • Our cases demonstrate the morphological features of the 'rosette-forming glioneuronal tumour of the fourth ventricle', a recently identified tumour characterised by its unique location, neurocytic pseudo-rosette formation and the presence of a low grade astrocytoma component.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology. Neuroglia / pathology
  • [MeSH-minor] Adult. Astrocytoma / metabolism. Astrocytoma / pathology. Astrocytoma / physiopathology. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Neurocytoma / metabolism. Neurocytoma / pathology. Neurocytoma / physiopathology

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  • (PMID = 16599951.001).
  • [ISSN] 0305-1846
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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94. Grzelak P, Górska-Chrzastek M, Gajewicz W, Kuśmierek J, Tybor K, Stefańczyk L: Recurrent cerebral gliomas in MRI and Iodine-123[corrected]-alpha-methyl-tyrosine SPECT: the use of digitally fused images. Nucl Med Rev Cent East Eur; 2005;8(2):94-9
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  • [Title] Recurrent cerebral gliomas in MRI and Iodine-123[corrected]-alpha-methyl-tyrosine SPECT: the use of digitally fused images.
  • BACKGROUND: Early detection and site location of recurrent cerebral glioma helps design optimum therapeutic regimen, which contributes to prolonged survival time of the patients.
  • The aim of the present study was to verify the usefulness of the calculated algorithm for a digital fusion of RM/SPECT images for the assessment of post-resection site of cerebral gliomas.
  • MATERIAL AND METHODS: The findings of MR and SPECT imaging for 21 patients who had surgery for cerebral glioma were subject to assessment.
  • Diagnosis was based on histopathology results (8 cases of anaplastic astrocytoma and 13 cases of multiform glioblastoma).
  • The fused images reflect the non-homogeneity of the post-resection site of cerebral gliomas.
  • CONCLUSIONS: The consistency of tumour locations detected with MR and SPECT was higher for tumours of the anaplastic astrocytoma type than for multiform glioblastomas (higher polymorphism of pathological changes).

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  • [ErratumIn] Nucl Med Rev Cent East Eur. 2006;9(1):93
  • (PMID = 16437393.001).
  • [ISSN] 1506-9680
  • [Journal-full-title] Nuclear medicine review. Central & Eastern Europe
  • [ISO-abbreviation] Nucl Med Rev Cent East Eur
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Radiopharmaceuticals
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95. Hirai T, Murakami R, Nakamura H, Kitajima M, Fukuoka H, Sasao A, Akter M, Hayashida Y, Toya R, Oya N, Awai K, Iyama K, Kuratsu JI, Yamashita Y: Prognostic value of perfusion MR imaging of high-grade astrocytomas: long-term follow-up study. AJNR Am J Neuroradiol; 2008 Sep;29(8):1505-10
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  • [Title] Prognostic value of perfusion MR imaging of high-grade astrocytomas: long-term follow-up study.
  • BACKGROUND AND PURPOSE: Although the prognostic value of perfusion MR imaging in various gliomas has been investigated, that in high-grade astrocytomas alone has not been fully evaluated.
  • The purpose of this study was to evaluate retrospectively whether the tumor maximum relative cerebral blood volume (rCBV) on pretreatment perfusion MR imaging is of prognostic value in patients with high-grade astrocytoma.
  • MATERIALS AND METHODS: Between January 1999 and December 2002, 49 patients (30 men, 19 women; age range, 23-76 years) with supratentorial high-grade astrocytoma underwent MR imaging before the inception of treatment.
  • RESULTS: The maximum rCBV was significantly higher in the 31 patients with glioblastoma multiforme than in the 18 with anaplastic astrocytoma (P < .03).
  • CONCLUSION: The maximum rCBV at pretreatment perfusion MR imaging is a useful clinical prognostic biomarker for survival in patients with high-grade astrocytoma.
  • [MeSH-major] Astrocytoma / diagnosis. Astrocytoma / mortality. Brain Neoplasms / diagnosis. Brain Neoplasms / mortality. Magnetic Resonance Imaging / methods

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  • (PMID = 18556364.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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96. Le Bas JF, Grand S, Kremer S, Tropres I, Jiang Z, Krainik A, Remy C, Berger F, Benabid AL: [Perfusion MR imaging for initial diagnosis and follow-up of brain tumors]. Neurochirurgie; 2005 Sep;51(3-4 Pt 2):287-98
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  • Images were thus obtained with intensities proportional to the cerebral blood volume (CBV).
  • Relative cerebral blood volume (rCBV) maps were then generated by normalizing the signal intensities with respect to measurements made in healthy tissue.
  • RESULTS: The method provided interesting data for establishing the differential diagnosis between different kinds of lesions, in particular between lymphoma and pilocytic astrocytoma, and for grading gliomas.
  • [MeSH-minor] Astrocytoma / blood supply. Astrocytoma / diagnosis. Astrocytoma / surgery. Biopsy. Brain / pathology. Brain / radionuclide imaging. Brain / surgery. Cerebrovascular Circulation. Diagnosis, Differential. Female. Follow-Up Studies. Glioma / blood supply. Glioma / diagnosis. Glioma / surgery. Humans. Lymphoma / diagnosis. Lymphoma / surgery. Magnetic Resonance Imaging. Male. Meningeal Neoplasms / blood supply. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / surgery. Meningioma / blood supply. Meningioma / diagnosis. Meningioma / surgery. Middle Aged. Neoplasm Staging. Tomography, Emission-Computed, Single-Photon

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  • (PMID = 16292173.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] France
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97. Julow J, Szeifert GT, Bálint K, Nyáry I, Nemes Z: The role of microglia/macrophage system in the tissue response to I-125 interstitial brachytherapy of cerebral gliomas. Neurol Res; 2007 Apr;29(3):233-8
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  • [Title] The role of microglia/macrophage system in the tissue response to I-125 interstitial brachytherapy of cerebral gliomas.
  • OBJECTIVE: To study histopathologic changes and the role of the microglia/macrophage cell in the therapeutic effect of I-125 interstitial brachytherapy on the cerebral gliomas.
  • METHODS: Out of a series of 60 cases with cerebral astrocytomas and other brain tumors treated with I-125 interstitial brachytherapy, autopsy materials were available in ten cases 0.75 and 60 months after irradiation.

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  • (PMID = 17509220.001).
  • [ISSN] 0161-6412
  • [Journal-full-title] Neurological research
  • [ISO-abbreviation] Neurol. Res.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD31; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Glial Fibrillary Acidic Protein; 0 / Iodine Radioisotopes; EC 5.4.2.2 / PGM1 protein, human; EC 5.4.2.2 / Phosphoglucomutase
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98. Dunn IF, Woodworth GF, Siddiqui AH, Smith ER, Vates GE, Day AL, Goumnerova LC: Traumatic pericallosal artery aneurysm: a rare complication of transcallosal surgery. Case report. J Neurosurg; 2007 Feb;106(2 Suppl):153-7
MedlinePlus Health Information. consumer health - Brain Aneurysm.

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  • The most common location of such lesions in children is the pericallosal or adjacent branch of the anterior cerebral artery, where a head impact exerts sudden decelerating shearing forces on the arteries tethered on the brain surface against an immobile falx cerebri, weakening the arterial wall.
  • This 6-year-old boy underwent resection of a hypothalamic pilocytic astrocytoma, which was approached via the transcallosal corridor.
  • [MeSH-major] Astrocytoma / surgery. Corpus Callosum / blood supply. Hypothalamic Neoplasms / surgery. Intracranial Aneurysm / etiology. Intraoperative Complications

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  • [CommentIn] J Neurosurg Pediatr. 2009 Jun;3(6):542; author reply 542 [19485744.001]
  • (PMID = 17330545.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Aronica E, Gorter JA, Redeker S, van Vliet EA, Ramkema M, Scheffer GL, Scheper RJ, van der Valk P, Leenstra S, Baayen JC, Spliet WG, Troost D: Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain. Epilepsia; 2005 Jun;46(6):849-57
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Several epileptogenic pathologies, such as hippocampal sclerosis (HS), focal cortical dysplasia (FCD), dysembryoplastic neuroepithelial tumor, oligodendroglioma astrocytoma, and glioblastoma multiforme were studied by using Western blot and immunocytochemistry.
  • The higher expression observed in astrocytomas by Western blot analysis was related to the higher vascular density within the tumor tissue.
  • [MeSH-minor] Astrocytoma / chemistry. Blotting, Western. Cerebral Cortex / abnormalities. Cerebral Cortex / chemistry. Cerebral Cortex / metabolism. Hippocampus / metabolism. Hippocampus / pathology. Humans. Immunohistochemistry. Microcirculation. Oligodendroglioma / chemistry. Oligodendroglioma / metabolism. Sclerosis. Tissue Distribution

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  • (PMID = 15946326.001).
  • [ISSN] 0013-9580
  • [Journal-full-title] Epilepsia
  • [ISO-abbreviation] Epilepsia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ABCG2 protein, human; 0 / Multidrug Resistance-Associated Proteins; 0 / Neoplasm Proteins
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100. Maia AC Jr, Malheiros SM, da Rocha AJ, da Silva CJ, Gabbai AA, Ferraz FA, Stávale JN: MR cerebral blood volume maps correlated with vascular endothelial growth factor expression and tumor grade in nonenhancing gliomas. AJNR Am J Neuroradiol; 2005 Apr;26(4):777-83
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MR cerebral blood volume maps correlated with vascular endothelial growth factor expression and tumor grade in nonenhancing gliomas.
  • BACKGROUND AND PURPOSE: Relative cerebral blood volume (rCBV) measurements derived from perfusion-weighted imaging (PWI) may be useful to evaluate angiogenesis and preoperatively estimate the grade of a glioma.
  • RESULTS: Nine patients had diffuse astrocytomas (World Health Organization grade II), and 11 had other LGG and anaplastic gliomas.
  • In patients with heterogeneous tumors on PWI, the high-rCBV focus had areas of oligodendroglioma or anaplastic astrocytoma on stereotactic biopsy, whereas the surgical specimens were predominantly astrocytomas.
  • Diffuse astrocytomas had negative VEGF expression and mean rCBV values significantly lower than those of the other two groups.
  • Three diffuse astrocytomas had positive VEGF immunoreactivity and high rCBV values.

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  • (PMID = 15814920.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A
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