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1. Carroll-Anzinger D, Kumar A, Adarichev V, Kashanchi F, Al-Harthi L: Human immunodeficiency virus-restricted replication in astrocytes and the ability of gamma interferon to modulate this restriction are regulated by a downstream effector of the Wnt signaling pathway. J Virol; 2007 Jun;81(11):5864-71
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  • We previously established that this restriction can be partly overcome by priming astrocytes with gamma interferon (IFN-gamma), which is elevated in the cerebral spinal fluid of HAD patients.
  • Blocking TCF-4 activity with a dominant-negative mutant enhanced HIV replication by threefold in both the astrocytoma cell line U87MG and primary fetal astrocytes.

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  • (PMID = 17392368.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Repressor Proteins; 0 / TCF Transcription Factors; 0 / TCF7L2 protein, human; 0 / Transcription Factor 7-Like 2 Protein; 0 / Wnt Proteins; 82115-62-6 / Interferon-gamma
  • [Other-IDs] NLM/ PMC1900315
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2. Cao Y, Tsien CI, Nagesh V, Junck L, Ten Haken R, Ross BD, Chenevert TL, Lawrence TS: Survival prediction in high-grade gliomas by MRI perfusion before and during early stage of RT [corrected]. Int J Radiat Oncol Biol Phys; 2006 Mar 01;64(3):876-85
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  • PURPOSE: To determine whether cerebral blood volume (CBV) and cerebral blood flow can predict the response of high-grade gliomas to radiotherapy (RT) by taking into account spatial heterogeneity and temporal changes in perfusion.
  • [MeSH-major] Astrocytoma / blood supply. Astrocytoma / radiotherapy. Brain Neoplasms / blood supply. Brain Neoplasms / radiotherapy. Cerebrovascular Circulation. Magnetic Resonance Imaging / methods

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  • [ErratumIn] Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):960
  • (PMID = 16298499.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R21 CA113699; United States / NCI NIH HHS / CA / R21 CA11369901; United States / NCI NIH HHS / CA / P01 CA85878; United States / NCI NIH HHS / CA / 2 PO1 CA59827
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 7S5I7G3JQL / Dexamethasone
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3. Iun'pén V, Oliushin VE, Ulitin AIu, Maslova LN, Petrov AA: [Long-term results of treatment in patients with oligodendrogliomas and oligoastrocytomas of the cerebral hemispheres]. Zh Vopr Neirokhir Im N N Burdenko; 2008 Apr-Jun;(2):6-10; discussion 10-1
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  • [Title] [Long-term results of treatment in patients with oligodendrogliomas and oligoastrocytomas of the cerebral hemispheres].
  • BACKGROUND: the current approach to treating patients with cerebral oligodendrogliomas and oligoastrocytomas involves surgical treatment with the maximum tumor resection in reasonable ranges, by taking into account the anatomic and physiological availability, followed by chemo- and radiotherapy.
  • [MeSH-major] Astrocytoma / therapy. Brain Neoplasms / therapy. Oligodendroglioma / therapy

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  • (PMID = 18720725.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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4. Lee FY, Jan YJ, Wen MC, Li MC, Wang J, Wen-Hsien C: A 32-year-old man with a fourth ventricular mass. Brain Pathol; 2009 Apr;19(2):333-6
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  • The features noted are suggestive of a probable better prognosis in this variant of low-grade astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology

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  • (PMID = 19291000.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins
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5. De Jesús ML, Sallés J, Meana JJ, Callado LF: Characterization of CB1 cannabinoid receptor immunoreactivity in postmortem human brain homogenates. Neuroscience; 2006 Jun 30;140(2):635-43
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  • Studies of CB1 in rat cerebral tissue are scarce, and even less is known regarding the expression of CB1 in the human brain.
  • These data were confirmed by blotting experiments carried out with human U373MG astrocytoma cells as a positive control for CB1 expression and wild-type CHO cells as negative control.

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  • (PMID = 16563642.001).
  • [ISSN] 0306-4522
  • [Journal-full-title] Neuroscience
  • [ISO-abbreviation] Neuroscience
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cannabinoid Receptor Modulators; 0 / Receptor, Cannabinoid, CB1
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6. Mohamed IS, Otsubo H, Shroff M, Donner E, Drake J, Snead OC 3rd: Magnetoencephalography and diffusion tensor imaging in gelastic seizures secondary to a cingulate gyrus lesion. Clin Neurol Neurosurg; 2007 Feb;109(2):182-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging. Epilepsies, Partial / etiology. Gyrus Cinguli. Magnetoencephalography
  • [MeSH-minor] Adolescent. Brain Mapping. Diagnosis, Differential. Dominance, Cerebral / physiology. Electroencephalography. Humans. Male. Nerve Fibers / pathology. Theta Rhythm

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  • (PMID = 16887259.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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7. Law M, Oh S, Babb JS, Wang E, Inglese M, Zagzag D, Knopp EA, Johnson G: Low-grade gliomas: dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging--prediction of patient clinical response. Radiology; 2006 Feb;238(2):658-67
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: To determine retrospectively whether relative cerebral blood volume (CBV) measurements can be used to predict clinical response in patients with low-grade gliomas.
  • Thirty-five patients (23 male and 12 female patients; median age, 39 years; range, 4-80 years) with histologically diagnosed low-grade gliomas (21 low-grade astrocytomas and 14 low-grade oligodendrogliomas and low-grade mixed oligoastrocytomas) were examined with dynamic susceptibility-weighted contrast material-enhanced perfusion magnetic resonance (MR) imaging.
  • [MeSH-major] Astrocytoma / therapy. Brain Neoplasms / therapy. Magnetic Resonance Imaging. Oligodendroglioma / therapy

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  • [Copyright] (c) RSNA, 2006
  • [CommentIn] Radiology. 2008 Mar;246(3):989 [18309030.001]
  • (PMID = 16396838.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01CA093992
  • [Publication-type] Duplicate Publication; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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8. Park MJ, Kim HS, Jahng GH, Ryu CW, Park SM, Kim SY: Semiquantitative assessment of intratumoral susceptibility signals using non-contrast-enhanced high-field high-resolution susceptibility-weighted imaging in patients with gliomas: comparison with MR perfusion imaging. AJNR Am J Neuroradiol; 2009 Aug;30(7):1402-8
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  • We determined whether the degree of intratumoral susceptibility signal intensity (ITSS) on HR-SWI correlates with maximum relative cerebral blood volume (rCBVmax) and to compare its diagnostic accuracy for glioma grading with that of dynamic susceptibility contrast (DSC) perfusion MR imaging.
  • MATERIALS AND METHODS: Forty-one patients with diffuse astrocytomas underwent both non-contrast-enhanced HR-SWI and DSC at 3T.
  • [MeSH-major] Astrocytoma / diagnosis. Brain / pathology. Brain Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging / methods. Image Enhancement / methods. Image Interpretation, Computer-Assisted / methods. Perfusion Imaging / methods

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  • (PMID = 19369602.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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9. Ishihara H, Kubota H, Lindberg RL, Leppert D, Gloor SM, Errede M, Virgintino D, Fontana A, Yonekawa Y, Frei K: Endothelial cell barrier impairment induced by glioblastomas and transforming growth factor beta2 involves matrix metalloproteinases and tight junction proteins. J Neuropathol Exp Neurol; 2008 May;67(5):435-48
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  • Occludin, claudin 1, and claudin 5 were expressed in microvascular endothelial cells in nonneoplastic brain samples but were significantly reduced in anaplastic astrocytoma and glioblastoma samples.
  • [MeSH-minor] Brain / blood supply. Brain / pathology. Brain / physiopathology. Brain Edema / metabolism. Brain Edema / pathology. Brain Edema / physiopathology. Cells, Cultured. Cerebral Arteries / metabolism. Cerebral Arteries / pathology. Cerebral Arteries / physiopathology. Claudin-1. Claudin-5. Coculture Techniques. Down-Regulation / physiology. Extracellular Matrix / metabolism. Extracellular Matrix / pathology. Humans. Infant, Newborn. Membrane Proteins / metabolism. Occludin. Tumor Cells, Cultured

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  • Gene Ontology. gene/protein/disease-specific - Gene Ontology annotations from this paper .
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  • (PMID = 18431253.001).
  • [ISSN] 0022-3069
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CLDN1 protein, human; 0 / CLDN5 protein, human; 0 / Claudin-1; 0 / Claudin-5; 0 / Membrane Proteins; 0 / OCLN protein, human; 0 / Occludin; 0 / Transforming Growth Factor beta2; EC 3.4.24.- / Matrix Metalloproteinases
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10. Richter S, Schoch B, Kaiser O, Groetschel H, Hein-Kropp C, Maschke M, Dimitrova A, Gizewski E, Ziegler W, Karnath HO, Timmann D: Children and adolescents with chronic cerebellar lesions show no clinically relevant signs of aphasia or neglect. J Neurophysiol; 2005 Dec;94(6):4108-20
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  • We studied language and visuospatial functions of 12 children and adolescents who had undergone surgery for cerebellar astrocytoma without subsequent radiation or chemotherapy and compared them with 27 age-, gender-, and education-matched healthy control subjects.
  • To study possible lateralization of the functions of the left and right cerebellar hemispheres, subjects performed several language tasks including a verb-generation task as well as standard neglect and extinction tests.
  • Three-dimensional-MR images confirmed that lesions affected cerebellar hemispheres in all children but one who had a pure vermal lesion.
  • The right cerebellar hemisphere was affected in six, the left hemisphere in four children, and both hemispheres in one child.
  • [MeSH-major] Aphasia / physiopathology. Astrocytoma / physiopathology. Attention / physiology. Cerebellar Neoplasms / physiopathology. Language. Perceptual Disorders / physiopathology
  • [MeSH-minor] Adolescent. Adult. Age Factors. Brain Mapping. Case-Control Studies. Child. Dominance, Cerebral / physiology. Female. Humans. Language Tests / statistics & numerical data. Magnetic Resonance Imaging / methods. Male. Reaction Time / physiology. Space Perception / physiology. Verbal Behavior / physiology

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  • (PMID = 16033937.001).
  • [ISSN] 0022-3077
  • [Journal-full-title] Journal of neurophysiology
  • [ISO-abbreviation] J. Neurophysiol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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11. Essig M, Giesel F, Stieltjes B, Weber MA: [Functional imaging for brain tumors (perfusion, DTI and MR spectroscopy)]. Radiologe; 2007 Jun;47(6):513-9
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  • PWI allows better estimates of biological activity and aggressiveness in low grade brain tumors, and in the case of WHO grade II astrocytoma showing anaplasically transformed tumor areas, allows more rapid visu-alization and a better prediction of the course of the disease than conventional MRI diagnostics.
  • Diffusion MRI, due to the directional dependence of the diffusion, can illustrate the course and direction of the nerve fibers, as well as reconstructing the nerve tracts in the cerebrum, pons and cerebellum 3-dimensionally.
  • Diagnostic problems such as the differentiation between neoplastic and non-neoplastic lesions, grading cerebral glioma and distinguishing between primary brain tumors and metastases can be resolved.

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  • (PMID = 17505814.001).
  • [ISSN] 0033-832X
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 21
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12. Fayed N, Modrego PJ: The contribution of magnetic resonance spectroscopy and echoplanar perfusion-weighted MRI in the initial assessment of brain tumours. J Neurooncol; 2005 May;72(3):261-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We found no significant differences in the relative cerebral blood volume (rCBV) for every type of tumour.
  • [MeSH-minor] Adolescent. Adult. Aged. Astrocytoma / chemistry. Astrocytoma / diagnosis. Astrocytoma / pathology. Blood Volume / physiology. Child. Child, Preschool. Choline / metabolism. Creatine / metabolism. Creatinine / metabolism. Female. Glioma / chemistry. Glioma / diagnosis. Glioma / pathology. Humans. Lactates / metabolism. Male. Middle Aged. Neoplasm Metastasis / diagnosis. ROC Curve. Tomography, X-Ray Computed

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  • [Cites] AJNR Am J Neuroradiol. 2004 Feb;25(2):214-21 [14970020.001]
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  • (PMID = 15937650.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lactates; AYI8EX34EU / Creatinine; MU72812GK0 / Creatine; N91BDP6H0X / Choline
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13. Bisdas S, Kirkpatrick M, Giglio P, Welsh C, Spampinato MV, Rumboldt Z: Cerebral blood volume measurements by perfusion-weighted MR imaging in gliomas: ready for prime time in predicting short-term outcome and recurrent disease? AJNR Am J Neuroradiol; 2009 Apr;30(4):681-8
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  • [Title] Cerebral blood volume measurements by perfusion-weighted MR imaging in gliomas: ready for prime time in predicting short-term outcome and recurrent disease?
  • Our aim was to determine whether the relative cerebral volume (rCBV) measurements in gliomas may serve as an adjunct to histopathologic grading, with a hypothesis that rCBV values are more accurate in predicting 1-year survival and recurrence.
  • MATERIALS AND METHODS: Thirty-four patients with gliomas (WHO grade I-IV, 27 astrocytomas, 7 tumors with oligodendroglial components) underwent contrast-enhanced MR rCBV measurements before treatment.
  • The rCBV(mean) and rCBV(max) in the astrocytomas were 3.5 +/- 2.9 and 3.7 +/- 2.7.
  • CONCLUSIONS: rCBV values in astrocytomas but not tumors with oligodendroglial components are predictive for recurrence and 1-year survival and may be more accurate than histopathologic grading.
  • [MeSH-major] Astrocytoma / pathology. Blood Volume. Brain Neoplasms / pathology. Cerebrovascular Circulation. Magnetic Resonance Imaging / methods. Oligodendroglioma / pathology

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  • (PMID = 19179427.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Kondageski C, Pierre-Kahn A, Carbonne B, Brunelle F: Association of a fetal quadrigeminal cyst with a possibly congenital thalamic astrocytoma. Childs Nerv Syst; 2005 Apr;21(4):317-21
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  • [Title] Association of a fetal quadrigeminal cyst with a possibly congenital thalamic astrocytoma.
  • CASE REPORT: This article reports on the exceptional association of a fetal quadrigeminal malformative cyst with a possibly congenital pilocytic astrocytoma of the pulvinar.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Cerebral Aqueduct / pathology. Fetal Diseases / pathology. Pulvinar / pathology

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  • (PMID = 15459783.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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15. Ide T, Miyoshi N, Ochiai K, Yasuda N: Oligoastrocytoma of the brain in a hooded crane (Grus monacha). Vet Pathol; 2009 Mar;46(2):309-12
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  • A cerebral tumor was identified at necropsy in a mature female hooded crane (Grus monacha).
  • On histologic examination, the tumor was mainly composed of 2 discrete components that resembled oligodendroglioma and astrocytoma.
  • [MeSH-major] Astrocytoma / veterinary. Bird Diseases / pathology

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  • (PMID = 19261644.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Maia AC Jr, Malheiros SM, da Rocha AJ, da Silva CJ, Gabbai AA, Ferraz FA, Stávale JN: MR cerebral blood volume maps correlated with vascular endothelial growth factor expression and tumor grade in nonenhancing gliomas. AJNR Am J Neuroradiol; 2005 Apr;26(4):777-83
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  • [Title] MR cerebral blood volume maps correlated with vascular endothelial growth factor expression and tumor grade in nonenhancing gliomas.
  • BACKGROUND AND PURPOSE: Relative cerebral blood volume (rCBV) measurements derived from perfusion-weighted imaging (PWI) may be useful to evaluate angiogenesis and preoperatively estimate the grade of a glioma.
  • RESULTS: Nine patients had diffuse astrocytomas (World Health Organization grade II), and 11 had other LGG and anaplastic gliomas.
  • In patients with heterogeneous tumors on PWI, the high-rCBV focus had areas of oligodendroglioma or anaplastic astrocytoma on stereotactic biopsy, whereas the surgical specimens were predominantly astrocytomas.
  • Diffuse astrocytomas had negative VEGF expression and mean rCBV values significantly lower than those of the other two groups.
  • Three diffuse astrocytomas had positive VEGF immunoreactivity and high rCBV values.

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  • (PMID = 15814920.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A
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17. Nagatani M, Yamakawa S, Ando R, Edamoto H, Saito T, Tamura K: Highly invasive intracranial malignant schwannoma in a rat. J Toxicol Pathol; 2009 Jun;22(2):139-42
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  • In the brain, the tumor cells infiltrated diffusely into the leptomeningeal and perivascular spaces and parenchyma, in which the tumor cell morphology and invasive pattern closely resembled those of malignant astrocytoma and malignant reticulosis.
  • Immunohistochemically, the tumor cells in the masses showed positive reactions for both S-100 protein and GFAP, while those in the cerebral invasion sites were negative for GFAP and less positive for S-100 protein.

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  • (PMID = 22271987.001).
  • [ISSN] 0914-9198
  • [Journal-full-title] Journal of toxicologic pathology
  • [ISO-abbreviation] J Toxicol Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Other-IDs] NLM/ PMC3246059
  • [Keywords] NOTNLM ; cranial cavity / malignant schwannoma / rat / spontaneous
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18. Choi JW, Lee MM, Kim IA, Kim JH, Choe G, Kim CY: The outcomes of concomitant chemoradiotherapy followed by adjuvant chemotherapy with temozolomide for newly diagnosed high grade gliomas : the preliminary results of single center prospective study. J Korean Neurosurg Soc; 2008 Oct;44(4):222-7
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  • OBJECTIVE: Malignant gliomas are the most common primary cerebral neoplasms in adults.
  • Pathologically, glioblastoma, anaplastic astrocytoma, anaplastic oligodendroglioma, and gliomatosis cerebri had been diagnosed in eighteen, eight, four, and two patients, respectively.

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  • (PMID = 19096681.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588321
  • [Keywords] NOTNLM ; Concomitant chemoradiotherapy / Glioblastoma / High-grade glioma / Temozolomide
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19. Hauck EF, McGinnis M, Nauta HJ: Cerebral phaeohyphomycosis mimics high-grade astrocytoma. J Clin Neurosci; 2008 Sep;15(9):1061-6
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  • [Title] Cerebral phaeohyphomycosis mimics high-grade astrocytoma.
  • The incidence of cerebral phaeohyphomycosis, an infection caused by a dark-pigmented fungus, is increasing.
  • We report two cases to increase the awareness of cerebral phaeohyphomycosis in the clinical neurosciences.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Abscess / microbiology. Brain Abscess / pathology. Brain Neoplasms / diagnosis. Central Nervous System Fungal Infections / microbiology. Central Nervous System Fungal Infections / pathology

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  • (PMID = 18614370.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Antifungal Agents
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20. Dutta D, Vanere P, Gupta T, Munshi A, Jalali R: Factors influencing activities of daily living using FIM-FAM scoring system before starting adjuvant treatment in patients with brain tumors: results from a prospective study. J Neurooncol; 2009 Aug;94(1):103-10
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  • Glioblastoma (GBM) (23.3%), anaplastic astrocytoma (AA) (18.7%), and diffuse fibrillary astrocytoma (18.7%) were the commonest histologic subtypes.
  • Univariate analysis showed total FIM-FAM scores not significantly different with age (< or =35 years vs. >35 years; P = 0.994), sex (male versus female; P = 0.133), and grade of the tumor (high-grade versus low-grade; P = 0.142) but were significantly higher in patients with a Karnofsky performance score (KPS) of > or =70 as compared with <70 (P = 0.001), neurological performance scale (NPS) of 0 or 1 vs. 2 or 3; P = 0.001), disease type (benign versus malignant; P = 0.001), and site of disease (cerebral versus cerebellar; P = 0.024).

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  • (PMID = 19255726.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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21. Hermann EJ, Hattingen E, Krauss JK, Marquardt G, Pilatus U, Franz K, Setzer M, Gasser T, Tews DS, Zanella FE, Seifert V, Lanfermann H: Stereotactic biopsy in gliomas guided by 3-tesla 1H-chemical-shift imaging of choline. Stereotact Funct Neurosurg; 2008;86(5):300-7
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  • OBJECTIVE: To investigate chemical-shift imaging (CSI) to guide stereotactic biopsy of the choline 'hot spot' in cerebral lesions suggestive of low-grade glioma.
  • [MeSH-major] Astrocytoma / pathology. Biopsy / methods. Brain Neoplasms / pathology. Choline / metabolism. Magnetic Resonance Spectroscopy / methods. Stereotaxic Techniques

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  • Hazardous Substances Data Bank. CHOLINE CHLORIDE .
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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18791331.001).
  • [ISSN] 1423-0372
  • [Journal-full-title] Stereotactic and functional neurosurgery
  • [ISO-abbreviation] Stereotact Funct Neurosurg
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Protons; N91BDP6H0X / Choline
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22. Tsutsumi S, Higo T, Kondo A, Abe Y, Yasumoto Y, Ito M: Atypical cervical astrocytoma manifesting as occipitalgia. Neurol Med Chir (Tokyo); 2007 Aug;47(8):371-4
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  • [Title] Atypical cervical astrocytoma manifesting as occipitalgia.
  • Cerebral magnetic resonance (MR) imaging showed no corresponding lesions.
  • Histological examination identified diffuse astrocytoma.
  • Cervical astrocytoma of subpial location is a very rare cause of headache in adults.
  • [MeSH-major] Astrocytoma / complications. Astrocytoma / pathology. Headache / etiology. Spinal Cord / pathology. Spinal Cord Neoplasms / complications. Spinal Cord Neoplasms / pathology

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  • (PMID = 17721055.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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23. Hayashi M, Hachiya Y, Arai N: An autopsy case presenting repetitive hypoglycemia and unique cortical dysplasia. Brain Dev; 2010 Apr;32(4):289-92
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  • In epileptic patients, focal cortical dysplasia (FCD) is pathologically characterized by irregular cortical lamination, blurring of the grey and white matter border and the occurrence of dysplastic cells in the cerebral cortex.
  • A well-demarcated pilocytic astrocytoma was present in the brainstem.

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  • [Copyright] Copyright (c) 2009 Elsevier B.V. All rights reserved.
  • (PMID = 19303727.001).
  • [ISSN] 1872-7131
  • [Journal-full-title] Brain & development
  • [ISO-abbreviation] Brain Dev.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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24. Young GS, Setayesh K: Spin-echo echo-planar perfusion MR imaging in the differential diagnosis of solitary enhancing brain lesions: distinguishing solitary metastases from primary glioma. AJNR Am J Neuroradiol; 2009 Mar;30(3):575-7
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  • Unlike the more widely reported gradient-echo echo-planar perfusion-weighted imaging (EPI-PWI) technique, spin-echo (SE) EPI relative cerebral blood volume maps select for blood volume in microvessels <8 microm in diameter.
  • [MeSH-minor] Adenocarcinoma / secondary. Adult. Aged. Astrocytoma / pathology. Breast Neoplasms / pathology. Carcinoma, Basal Cell / secondary. Colorectal Neoplasms / pathology. Diagnosis, Differential. Esophageal Neoplasms / pathology. Female. Humans. Lung Neoplasms / pathology. Male. Melanoma / secondary. Middle Aged. Models, Neurological. Prostatic Neoplasms / pathology. Retrospective Studies. Sensitivity and Specificity. Skin Neoplasms / pathology

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  • (PMID = 19095787.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article; Technical Report
  • [Publication-country] United States
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25. Hercules SA, Ramesh VG, Paramasivan S, Kodiarasan P, Kumar MS: Holoventricular glioma in a child. Case report. J Neurosurg; 2007 Feb;106(2 Suppl):134-5
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  • The authors report a unique case of a tetraventricular Grade II astrocytoma with evidence of extension into the basal cisterns in a 5-year-old boy who had a 1-month history of headache.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis
  • [MeSH-minor] Astrocytes / pathology. Cerebral Ventricles. Child, Preschool. Contrast Media. Humans. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness. Subarachnoid Space. Tomography, X-Ray Computed

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  • (PMID = 17330540.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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26. Szeifert GT, Prasad D, Kamyrio T, Steiner M, Steiner LE: The role of the Gamma Knife in the management of cerebral astrocytomas. Prog Neurol Surg; 2007;20:150-63
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  • [Title] The role of the Gamma Knife in the management of cerebral astrocytomas.
  • The aim of this study was to assess the role of Gamma Knife radiosurgery in the complex management of cerebral astrocytomas.
  • Out of a series with more than 1,000 brain tumor cases treated at the Lars Leksell Center for Gamma Knife Surgery, UVA, 74 astrocytomas were selected for the present review.
  • The tumor either disappeared or decreased in 60% of grade 1 astrocytomas (n = 15), and 71% tumor control was achieved in grade 2 astrocytomas (n = 17) following radiosurgery.
  • Results of the present analysis suggest that stereotactic radiosurgery represents an alternative or supplementary treatment modality to conventional surgery in small-volume low-grade astrocytomas especially in deep-seated critical locations.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Radiosurgery / methods

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  • (PMID = 17317983.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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27. Ramírez-Zamora A, Biller J: Brainstem cavernous malformations: a review with two case reports. Arq Neuropsiquiatr; 2009 Sep;67(3B):917-21
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  • [MeSH-major] Brain Stem. Cerebral Hemorrhage / etiology. Intracranial Arteriovenous Malformations / diagnosis. Pregnancy Complications, Cardiovascular / diagnosis
  • [MeSH-minor] Adult. Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Pregnancy. Radiotherapy / adverse effects

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  • (PMID = 19838533.001).
  • [ISSN] 1678-4227
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 40
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28. Adachi J, Nishikawa R, Hirose T, Matsutani M: Mixed neuronal-glial tumor of the fourth ventricle and successful treatment of postoperative mutism with bromocriptine: case report. Surg Neurol; 2005 Apr;63(4):375-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Bromocriptine / therapeutic use. Cerebral Ventricles / pathology. Dopamine Agonists / therapeutic use. Mutism / drug therapy. Mutism / etiology. Neurocytoma / surgery. Postoperative Complications / drug therapy

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  • (PMID = 15808729.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dopamine Agonists; 3A64E3G5ZO / Bromocriptine
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29. Maciá Escalante S, Rodríguez Lescure A, Segura Ibáñez JM, Sáez Castán J, Guillén Ponce C, Carrato Mena A: Patient with resected anaplastic astrocytoma and an image suggestive of relapse. Clin Transl Oncol; 2006 Dec;8(12):912-4
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  • [Title] Patient with resected anaplastic astrocytoma and an image suggestive of relapse.
  • With respect to the cerebral edema that can be associated with the carmustine implants, there can appear images in follow-up that are suggestive of relapse.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Edema / diagnostic imaging. Brain Neoplasms / diagnosis. Neoplasm Recurrence, Local / diagnosis

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  • [Cites] Invest New Drugs. 2004 Jan;22(1):27-37 [14707492.001]
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  • [ISO-abbreviation] Clin Transl Oncol
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30. Gozé C, Rigau V, Gibert L, Maudelonde T, Duffau H: Lack of complete 1p19q deletion in a consecutive series of 12 WHO grade II gliomas involving the insula: a marker of worse prognosis? J Neurooncol; 2009 Jan;91(1):1-5
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  • None complete deletion of the 1p and 19q arms chromosomes and partial deletions in 3 patients were retrieved in the 11 WHO grade II oligodendrogliomas and one oligo-astrocytoma analyzed.
  • [MeSH-major] Brain Neoplasms / genetics. Brain Neoplasms / pathology. Cerebral Cortex / pathology. Chromosome Deletion. Chromosomes, Human, Pair 19 / genetics. Glioma / genetics. Glioma / pathology

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  • (PMID = 18726074.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; EC 2.1.1.- / DNA Modification Methylases; EC 2.1.1.63 / MGMT protein, human; EC 6.5.1.- / DNA Repair Enzymes
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31. Fratzoglou M, Leite dos Santos AR, Gawish I, Perneczky A: Endoscope-assisted microsurgery for tumors of the septum pellucidum: surgical considerations and benefits of the method in the treatment of four serial cases. Neurosurg Rev; 2005 Jan;28(1):39-43
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  • The histological findings showed pilocytic astrocytoma in two cases, one subependymoma and one neurocytoma, respectively.
  • [MeSH-major] Cerebral Ventricle Neoplasms / surgery. Glioma / surgery. Microsurgery. Neurocytoma / surgery. Neuroendoscopy. Septum Pellucidum / surgery

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  • (PMID = 15138845.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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32. Waschbisch A, Fiebich BL, Akundi RS, Schmitz ML, Hoozemans JJ, Candelario-Jalil E, Virtainen N, Veerhuis R, Slawik H, Yrjänheikki J, Hüll M: Interleukin-1 beta-induced expression of the prostaglandin E-receptor subtype EP3 in U373 astrocytoma cells depends on protein kinase C and nuclear factor-kappaB. J Neurochem; 2006 Feb;96(3):680-93
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  • [Title] Interleukin-1 beta-induced expression of the prostaglandin E-receptor subtype EP3 in U373 astrocytoma cells depends on protein kinase C and nuclear factor-kappaB.
  • Here we describe IL-1beta-induced EP3 receptor expression in human astrocytoma cells, primary astrocytes of rat and human origin and in rat brain.
  • This might play an important role in acute and chronic conditions such as cerebral ischemia, traumatic brain injury, HIV-encephalitis, Alzheimer's disease and prion diseases in which a marked up-regulation of IL-1beta is followed by a prolonged increase of PGE2 levels in the brain.
  • [MeSH-major] Astrocytoma / metabolism. Gene Expression Regulation, Neoplastic / drug effects. Interleukin-1 / pharmacology. NF-kappa B / physiology. Protein Kinase C / physiology. Receptors, Prostaglandin E / metabolism

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  • (PMID = 16405508.001).
  • [ISSN] 0022-3042
  • [Journal-full-title] Journal of neurochemistry
  • [ISO-abbreviation] J. Neurochem.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Interleukin-1; 0 / NF-kappa B; 0 / PTGER3 protein, human; 0 / Ptger3 protein, rat; 0 / RNA, Messenger; 0 / Receptors, Prostaglandin E; 0 / Receptors, Prostaglandin E, EP3 Subtype; EC 2.7.11.13 / Protein Kinase C
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33. Yoshikawa G, Kawamoto S, Yakou K, Tsutsumi K: Massive intracranial hemorrhage associated with pleomorphic xanthoastrocytoma--case report. Neurol Med Chir (Tokyo); 2010;50(3):220-3
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  • Cerebral angiography on admission revealed occlusion of the P(2) segment of the left posterior cerebral artery (PCA) and extravasation of contrast medium during the procedure.
  • [MeSH-major] Aneurysm, False / etiology. Aneurysm, Ruptured / etiology. Astrocytoma / complications. Brain Neoplasms / complications. Hematoma, Subdural, Intracranial / etiology. Subarachnoid Hemorrhage / etiology
  • [MeSH-minor] Cerebral Angiography. Female. Humans. Middle Aged. Posterior Cerebral Artery. Severity of Illness Index. Temporal Lobe / blood supply. Temporal Lobe / pathology. Temporal Lobe / surgery. Treatment Outcome

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  • (PMID = 20339272.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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34. Tekkök IH: Hemorrhage in pleomorphic xanthoastrocytomas. J Neurooncol; 2006 Mar;77(1):105-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Cerebral Hemorrhage / etiology

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  • [CommentOn] J Neurooncol. 2005 Jan;71(2):169-71 [15690134.001]
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  • (PMID = 16292492.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] United States
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35. Broniscer A, Chintagumpala M, Fouladi M, Krasin MJ, Kocak M, Bowers DC, Iacono LC, Merchant TE, Stewart CF, Houghton PJ, Kun LE, Ledet D, Gajjar A: Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children. J Neurooncol; 2006 Feb;76(3):313-9
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  • Tumors most commonly involved cerebral hemispheres (n = 13, 42%) and thalamus (n = 14, 45%).
  • The predominant histologic diagnoses were glioblastoma multiforme (n = 15, 48%) and anaplastic astrocytoma (n = 10, 32%).
  • Two patients had bithalamic grade II astrocytoma.

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  • (PMID = 16200343.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA21765
  • [Publication-type] Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Antineoplastic Agents, Phytogenic; 0H43101T0J / irinotecan; 7GR28W0FJI / Dacarbazine; XT3Z54Z28A / Camptothecin; YF1K15M17Y / temozolomide
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36. Grau E, Balaguer J, Canete A, Martinez F, Orellana C, Oltra S, Hernandez M, Castel V: Subtelomeric analysis of pediatric astrocytoma: subchromosomal instability is a distinctive feature of pleomorphic xanthoastrocytoma. J Neurooncol; 2009 Jun;93(2):175-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subtelomeric analysis of pediatric astrocytoma: subchromosomal instability is a distinctive feature of pleomorphic xanthoastrocytoma.
  • Astrocytic neoplasms are genetically heterogeneous; however a low frequency of genomic changes has been found in juvenile pilocytic astrocytoma (PA) in molecular studies.
  • We studied the subtelomeric regions of 19 primary astrocytoma tumors.
  • These genetic differences would likely contribute to the more favorable behavior of PXAs and may be helpful for molecular differential diagnosis of pediatric cerebral tumors.
  • [MeSH-major] Astrocytoma / genetics. Chromosomal Instability / genetics. Glioma / genetics. Telomere / genetics

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  • (PMID = 19099200.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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37. Missler U, Zimmermann M, Grehl H: Atypical pilocytic astrocytoma of the third ventricle appearing as a colloid cyst. Klin Neuroradiol; 2009 Dec;19(4):301-5
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  • [Title] Atypical pilocytic astrocytoma of the third ventricle appearing as a colloid cyst.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Cerebral Ventricles / pathology
  • [MeSH-minor] Adult. Cerebral Ventriculography / methods. Colloid Cysts / complications. Colloid Cysts / diagnosis. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 19911121.001).
  • [ISSN] 1615-6706
  • [Journal-full-title] Klinische Neuroradiologie
  • [ISO-abbreviation] Klin Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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38. Katakowski M, Jiang F, Zheng X, Gutierrez JA, Szalad A, Chopp M: Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17. Cancer Sci; 2009 Sep;100(9):1597-604
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  • EGFR is a key component of autonomous growth signaling in several tumors, and correlates with the malignancy grade of astrocytoma.

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  • (PMID = 19515085.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA043892-17; United States / NCI NIH HHS / CA / R01 CA100486-04; United States / NCI NIH HHS / CA / P01 CA043892; United States / NCI NIH HHS / CA / CA100486-04; United States / NCI NIH HHS / CA / R01 CA100486; United States / NCI NIH HHS / CA / P01 CA043892-17
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inducing Agents; 0 / RNA, Messenger; 0 / Tumor Necrosis Factor-alpha; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 3.4.24.- / ADAM Proteins; EC 3.4.24.- / tumor necrosis factor-alpha convertase
  • [Other-IDs] NLM/ NIHMS142282; NLM/ PMC2756136
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39. Tung JN, Tsao TY, Tai CJ, Yeh KT, Cheng YW, Jiang MC: Distribution of lysosome-associated membrane proteins-1 and -2, and cathepsin D in eosinophilic granular bodies: possible relationship to cyst development in pilocytic astrocytomas. J Int Med Res; 2010 Jul-Aug;38(4):1354-64
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  • [Title] Distribution of lysosome-associated membrane proteins-1 and -2, and cathepsin D in eosinophilic granular bodies: possible relationship to cyst development in pilocytic astrocytomas.
  • Pilocytic astrocytomas are usually cystic; cyst formation within these tumours may result in increased intracranial pressure, due to the effect of their mass, and contribute to cerebral damage.
  • Eosinophilic granular bodies (EGBs) are produced abundantly in pilocytic astrocytomas but their role in disease progression remains unknown.
  • The results suggest that EGBs, together with other factors, may play a role in the development of cysts in pilocytic astrocytomas.
  • [MeSH-major] Astrocytoma / complications. Cathepsin D / metabolism. Cysts / complications. Cytoplasmic Granules / enzymology. Eosinophils / enzymology. Lysosome-Associated Membrane Glycoproteins / metabolism

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  • (PMID = 20926008.001).
  • [ISSN] 0300-0605
  • [Journal-full-title] The Journal of international medical research
  • [ISO-abbreviation] J. Int. Med. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / LAMP1 protein, human; 0 / LAMP2 protein, human; 0 / Lysosomal-Associated Membrane Protein 2; 0 / Lysosome-Associated Membrane Glycoproteins; EC 3.4.23.5 / Cathepsin D
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40. Wei CW, Guo G, Mikulis DJ: Tumor effects on cerebral white matter as characterized by diffusion tensor tractography. Can J Neurol Sci; 2007 Feb;34(1):62-8
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  • [Title] Tumor effects on cerebral white matter as characterized by diffusion tensor tractography.
  • In cerebral neoplasm, DTT can be used to illustrate the relationship of the tumor with respect to adjacent WM trajectories.
  • METHODS: Fiber tractography was used in this study to assess tumor-induced changes in WM trajectories in three cases of cerebral neoplasm: glioblastoma multiforme, meningioma, and anaplastic astrocytoma.
  • In anaplastic astrocytoma, fiber tracking demonstrated disruption of WM tracts at the tumor origin as well as intact axons through areas of tumor infiltration.
  • [MeSH-minor] Aged. Astrocytoma / diagnosis. Astrocytoma / physiopathology. Brain Mapping / methods. Corpus Callosum / pathology. Corpus Callosum / physiopathology. Disease Progression. Female. Glioblastoma / diagnosis. Glioblastoma / physiopathology. Humans. Image Processing, Computer-Assisted / methods. Magnetic Resonance Imaging / trends. Male. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / physiopathology. Meningioma / diagnosis. Meningioma / physiopathology. Middle Aged. Neoplasm Invasiveness. Predictive Value of Tests. Preoperative Care / methods. Preoperative Care / trends. Pyramidal Tracts / pathology. Pyramidal Tracts / physiopathology

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  • (PMID = 17352349.001).
  • [ISSN] 0317-1671
  • [Journal-full-title] The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • [ISO-abbreviation] Can J Neurol Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
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41. Felsberg J, Wolter M, Seul H, Friedensdorf B, Göppert M, Sabel MC, Reifenberger G: Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing. Acta Neuropathol; 2010 Apr;119(4):501-7
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  • [Title] Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing.
  • Diffusely infiltrating cerebral gliomas frequently carry point mutations in codon 132 of the isocitrate dehydrogenase 1 (IDH1) gene or in codon 172 of the IDH2 gene, which are both clinically important as diagnostic and prognostic markers.
  • [MeSH-major] Astrocytoma / genetics. Brain Neoplasms / genetics. DNA Mutational Analysis / methods. Isocitrate Dehydrogenase / genetics. Mutation. Oligodendroglioma / genetics

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  • (PMID = 20131059.001).
  • [ISSN] 1432-0533
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 1.1.1.41 / Isocitrate Dehydrogenase; EC 1.1.1.41 / isocitrate dehydrogenase 2, human; EC 1.1.1.42. / IDH1 protein, human
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42. de Ribaupierre S, Ryser C, Villemure JG, Clarke S: Cerebellar lesions: is there a lateralisation effect on memory deficits? Acta Neurochir (Wien); 2008 Jun;150(6):545-50; discussion 550
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  • In children, transient cerebellar mutism after resection has lead to a diminished use of midline approaches and vermis transection, as well as reduced retraction of the cerebellar hemispheres.
  • [MeSH-major] Amnesia / physiopathology. Cerebellar Neoplasms / physiopathology. Dominance, Cerebral / physiology
  • [MeSH-minor] Adolescent. Adult. Aged. Amnesia, Anterograde / diagnosis. Amnesia, Anterograde / physiopathology. Astrocytoma / diagnosis. Astrocytoma / physiopathology. Astrocytoma / surgery. Cerebellum / physiopathology. Cerebellum / surgery. Female. Follow-Up Studies. Glioblastoma / diagnosis. Glioblastoma / physiopathology. Glioblastoma / surgery. Hemangioblastoma / diagnosis. Hemangioblastoma / physiopathology. Hemangioblastoma / surgery. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / physiopathology. Hemangioma, Cavernous / surgery. Humans. Male. Medulloblastoma / diagnosis. Medulloblastoma / physiopathology. Medulloblastoma / surgery. Memory, Short-Term / physiology. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / physiopathology. Meningeal Neoplasms / surgery. Meningioma / diagnosis. Meningioma / physiopathology. Meningioma / surgery. Middle Aged. Neuropsychological Tests. Postoperative Complications / diagnosis. Postoperative Complications / physiopathology. Verbal Learning / physiology

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  • (PMID = 18512000.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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43. Andres RH, Pendharkar AV, Kuhlen D, Mariani L: Ventricular enlargement due to acute hypernatremia in a patient with a ventriculoperitoneal shunt. J Neurosurg; 2010 Jul;113(1):82-4
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  • [MeSH-major] Antidiuretic Agents / adverse effects. Cerebral Ventricles / pathology. Deamino Arginine Vasopressin / adverse effects. Fluid Therapy / adverse effects. Hydrocephalus / surgery. Hypernatremia / complications. Postoperative Complications / etiology. Postoperative Complications / surgery. Substance Withdrawal Syndrome / etiology. Tomography, X-Ray Computed. Ventriculoperitoneal Shunt
  • [MeSH-minor] Acute Disease. Adult. Antineoplastic Agents / administration & dosage. Astrocytoma / complications. Astrocytoma / drug therapy. Astrocytoma / radiotherapy. Brain Stem Neoplasms / complications. Brain Stem Neoplasms / drug therapy. Brain Stem Neoplasms / radiotherapy. Chemotherapy, Adjuvant. Cranial Irradiation. Diagnosis, Differential. Diagnostic Errors. Equipment Failure Analysis. Humans. Hypertrophy. Male. Neoplasms, Multiple Primary / drug therapy. Neoplasms, Multiple Primary / radiotherapy. Pituitary Neoplasms / complications. Pituitary Neoplasms / drug therapy. Pituitary Neoplasms / radiotherapy. Tectum Mesencephali

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  • (PMID = 19911884.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antidiuretic Agents; 0 / Antineoplastic Agents; ENR1LLB0FP / Deamino Arginine Vasopressin
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44. Kumar VA, Knopp EA, Zagzag D: Magnetic resonance dynamic susceptibility-weighted contrast-enhanced perfusion imaging in the diagnosis of posterior fossa hemangioblastomas and pilocytic astrocytomas: initial results. J Comput Assist Tomogr; 2010 Nov-Dec;34(6):825-9
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  • [Title] Magnetic resonance dynamic susceptibility-weighted contrast-enhanced perfusion imaging in the diagnosis of posterior fossa hemangioblastomas and pilocytic astrocytomas: initial results.
  • OBJECTIVE: The purpose of this study was to compare the dynamic susceptibility-weighted contrast-enhanced (DSC) magnetic resonance (MR) perfusion and MR imaging findings between hemangioblastomas and pilocytic astrocytoma (PA).
  • The mean relative cerebral blood volume was 7.7 (SD, 1.0) in patients with hemangioblastomas and 1.8 (SD, 1.8) in patients with PAs.
  • CONCLUSIONS: Our preliminary findings demonstrate significantly higher DSC-MR imaging relative cerebral blood volumes in patients with hemangioblastomas when compared with patients with PAs.
  • [MeSH-major] Astrocytoma / diagnosis. Hemangioblastoma / diagnosis. Infratentorial Neoplasms / diagnosis. Magnetic Resonance Imaging / methods

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  • (PMID = 21084895.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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45. Schiffman JD, Chun N, Fisher PG, Dahl GV, Ford JM, Eggerding FA: Identification of a novel p53 in-frame deletion in a Li-Fraumeni-like family. Pediatr Blood Cancer; 2008 Apr;50(4):914-6
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  • We describe a 2-year-old female with a completely resected cerebral pilocytic astrocytoma who subsequently developed B-progenitor acute lymphoblastic leukemia (ALL).
  • [MeSH-minor] Astrocytoma / genetics. Base Sequence. Brain Neoplasms / genetics. Child, Preschool. DNA Mutational Analysis. Female. Germ-Line Mutation. Humans. Male. Middle Aged. Pedigree. Polymerase Chain Reaction. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 17554785.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53
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46. Jiménez L, Correa-Rivas M, Colón-Castillo L, Rivera-Zengotita M, Colón G, Vigo J, McBurney E: Pilomyxoid astrocytoma in unusual location in a child with neurofibromatosis type 1: case report and review of the literature. P R Health Sci J; 2010 Jun;29(2):123-6
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  • [Title] Pilomyxoid astrocytoma in unusual location in a child with neurofibromatosis type 1: case report and review of the literature.
  • Pilomyxoid astrocytoma (PMA) is a recently defined brain tumor believed to be a variant of pilocytic astrocytoma (PA), but with a more aggressive course.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebral Ventricle Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Neurofibromatosis 1


47. Josan V, Smith P, Kornberg A, Rickert C, Maixner W: Development of a pilocytic astrocytoma in a dysembryoplastic neuroepithelial tumor. Case report. J Neurosurg; 2007 Jun;106(6 Suppl):509-12
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  • [Title] Development of a pilocytic astrocytoma in a dysembryoplastic neuroepithelial tumor. Case report.
  • Dysembryoplastic neuroepithelial tumors (DNETs) are benign supratentorial tumors based in the cerebral cortex.
  • The authors report on a patient in whom a pilocytic astrocytoma developed within a DNET, raising questions regarding the classification of these lesions and the need for lifelong clinical and imaging surveillance.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Cerebral Cortex. Magnetic Resonance Imaging. Neoplasms, Second Primary / diagnosis. Neuroectodermal Tumors, Primitive / diagnosis


48. Chen X, Weigel D, Ganslandt O, Buchfelder M, Nimsky C: Diffusion tensor imaging and white matter tractography in patients with brainstem lesions. Acta Neurochir (Wien); 2007 Nov;149(11):1117-31; discussion 1131
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Mapping. Brain Stem Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging. Hemangioma, Cavernous, Central Nervous System / diagnosis. Image Processing, Computer-Assisted. Imaging, Three-Dimensional. Nerve Fibers, Myelinated / pathology. Nerve Net / pathology. Neuronavigation. Pons / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Brain Damage, Chronic / diagnosis. Brain Damage, Chronic / pathology. Brain Damage, Chronic / surgery. Cranial Nerve Diseases / diagnosis. Cranial Nerve Diseases / pathology. Dominance, Cerebral / physiology. Female. Humans. Male. Middle Aged. Neurologic Examination. Postoperative Complications / diagnosis. Postoperative Complications / pathology. Pyramidal Tracts / pathology. Pyramidal Tracts / surgery

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  • (PMID = 17712509.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Austria
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49. Shingu T, Akiyama Y, Daisu M, Maruyama N, Matsumoto Y, Miyazaki T, Nagai H, Yamamoto Y, Yamasaki T, Yoshida M, Maruyama R, Moritake K: Symptomatic hemorrhage associated with recurrent pilocytic astrocytoma with granulation tissue--case report. Neurol Med Chir (Tokyo); 2007 May;47(5):222-8
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  • [Title] Symptomatic hemorrhage associated with recurrent pilocytic astrocytoma with granulation tissue--case report.
  • A 51-year-old woman had been followed up for 10 years for recurrence of pilocytic astrocytoma 5 years after the initial treatment consisting of subtotal resection, chemotherapy, and radiation therapy.
  • Histological examination confirmed recurrent pilocytic astrocytoma with organizing hematoma and granulation tissue.
  • Although neither symptomatic hemorrhage nor late benign recurrence is common, careful long-term follow up is necessary for patients with pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Hemorrhage / etiology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 17527050.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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50. Grzelak P, Górska-Chrzastek M, Gajewicz W, Kuśmierek J, Tybor K, Stefańczyk L: Recurrent cerebral gliomas in MRI and Iodine-123[corrected]-alpha-methyl-tyrosine SPECT: the use of digitally fused images. Nucl Med Rev Cent East Eur; 2005;8(2):94-9
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  • [Title] Recurrent cerebral gliomas in MRI and Iodine-123[corrected]-alpha-methyl-tyrosine SPECT: the use of digitally fused images.
  • BACKGROUND: Early detection and site location of recurrent cerebral glioma helps design optimum therapeutic regimen, which contributes to prolonged survival time of the patients.
  • The aim of the present study was to verify the usefulness of the calculated algorithm for a digital fusion of RM/SPECT images for the assessment of post-resection site of cerebral gliomas.
  • MATERIAL AND METHODS: The findings of MR and SPECT imaging for 21 patients who had surgery for cerebral glioma were subject to assessment.
  • Diagnosis was based on histopathology results (8 cases of anaplastic astrocytoma and 13 cases of multiform glioblastoma).
  • The fused images reflect the non-homogeneity of the post-resection site of cerebral gliomas.
  • CONCLUSIONS: The consistency of tumour locations detected with MR and SPECT was higher for tumours of the anaplastic astrocytoma type than for multiform glioblastomas (higher polymorphism of pathological changes).

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  • [ErratumIn] Nucl Med Rev Cent East Eur. 2006;9(1):93
  • (PMID = 16437393.001).
  • [ISSN] 1506-9680
  • [Journal-full-title] Nuclear medicine review. Central & Eastern Europe
  • [ISO-abbreviation] Nucl Med Rev Cent East Eur
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Radiopharmaceuticals
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51. Jallo GI, Bognár L: Eyebrow surgery: the supraciliary craniotomy: technical note. Neurosurgery; 2006 Jul;59(1 Suppl 1):ONSE157-8; discussion ONSE157-8
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  • [MeSH-major] Astrocytoma / surgery. Cranial Fossa, Anterior / surgery. Craniotomy / methods. Frontal Bone / surgery. Minimally Invasive Surgical Procedures / methods. Optic Nerve Neoplasms / surgery. Sella Turcica / surgery
  • [MeSH-minor] Adolescent. Bone Plates / standards. Cerebral Arteries / anatomy & histology. Cerebral Arteries / surgery. Dura Mater / anatomy & histology. Dura Mater / surgery. Eyebrows / anatomy & histology. Female. Frontal Lobe / anatomy & histology. Frontal Lobe / surgery. Humans. Intraoperative Complications / prevention & control. Magnetic Resonance Imaging. Medical Illustration. Optic Chiasm / anatomy & histology. Optic Chiasm / pathology. Optic Chiasm / surgery. Postoperative Complications / etiology. Postoperative Complications / physiopathology. Postoperative Complications / prevention & control. Subarachnoid Space / anatomy & histology. Subarachnoid Space / surgery. Treatment Outcome

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  • (PMID = 16888559.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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52. Jain R, Ellika SK, Scarpace L, Schultz LR, Rock JP, Gutierrez J, Patel SC, Ewing J, Mikkelsen T: Quantitative estimation of permeability surface-area product in astroglial brain tumors using perfusion CT and correlation with histopathologic grade. AJNR Am J Neuroradiol; 2008 Apr;29(4):694-700
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  • Our hypothesis was that quantitative estimation of permeability surface area product (PS), cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT) in astroglial brain tumors by using PCT will correlate with glioma grade.
  • [MeSH-major] Astrocytoma / radiography. Brain Neoplasms / radiography. Capillary Permeability. Cerebrovascular Circulation. Tomography, X-Ray Computed

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  • (PMID = 18202239.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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53. Gupta B, Torchilin VP: Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice. Cancer Immunol Immunother; 2007 Aug;56(8):1215-23
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  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Antineoplastic Agents / therapeutic use. Astrocytoma / drug therapy. Brain Neoplasms / drug therapy. Doxorubicin / therapeutic use. Immunoconjugates / therapeutic use
  • [MeSH-minor] Animals. Apoptosis. Cell Line, Tumor. Cerebral Cortex. Drug Delivery Systems. Female. Humans. Injections. Injections, Subcutaneous. Liposomes / administration & dosage. Mice. Mice, Nude. Nucleosomes / immunology. Polyethylene Glycols / administration & dosage. Tumor Burden. Xenograft Model Antitumor Assays

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  • (PMID = 17219149.001).
  • [ISSN] 0340-7004
  • [Journal-full-title] Cancer immunology, immunotherapy : CII
  • [ISO-abbreviation] Cancer Immunol. Immunother.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL55519
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antineoplastic Agents; 0 / Immunoconjugates; 0 / Liposomes; 0 / Nucleosomes; 30IQX730WE / Polyethylene Glycols; 80168379AG / Doxorubicin
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54. Chong DY, Hirunwiwatkul P, McKeever PE, Trobe JD: Papilledema in obstructive hydrocephalus caused by giant cell astrocytoma of tuberous sclerosis. J Neuroophthalmol; 2007 Mar;27(1):50-4
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  • [Title] Papilledema in obstructive hydrocephalus caused by giant cell astrocytoma of tuberous sclerosis.
  • Total excision of the mass led to a pathologic diagnosis of giant cell astrocytoma.
  • Although the patient apparently escaped visual loss, other reports affirm that giant cell astrocytoma, a common tumor in TS, may go undetected for long enough to produce irreversible optic neuropathy from chronic papilledema.
  • [MeSH-major] Astrocytoma / complications. Cerebral Ventricle Neoplasms / complications. Hydrocephalus / complications. Papilledema / etiology. Tuberous Sclerosis / complications


55. Gupta B, Levchenko TS, Torchilin VP: TAT peptide-modified liposomes provide enhanced gene delivery to intracranial human brain tumor xenografts in nude mice. Oncol Res; 2007;16(8):351-9
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  • [MeSH-major] Astrocytoma / therapy. Brain Neoplasms / therapy. DNA / administration & dosage. Gene Products, tat / administration & dosage. Genes, tat / genetics. Genetic Therapy / methods
  • [MeSH-minor] Animals. Cerebral Cortex. Drug Administration Routes. Gene Transfer Techniques. Green Fluorescent Proteins / genetics. Humans. Injections, Intralesional. Liposomes. Mice. Mice, Nude. Neoplasm Transplantation. Transfection. Transplantation, Heterologous. Tumor Cells, Cultured. Up-Regulation. Xenograft Model Antitumor Assays

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  • (PMID = 17913043.001).
  • [ISSN] 0965-0407
  • [Journal-full-title] Oncology research
  • [ISO-abbreviation] Oncol. Res.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL55519
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gene Products, tat; 0 / Liposomes; 147336-22-9 / Green Fluorescent Proteins; 9007-49-2 / DNA
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56. Joseph V, Wells A, Kuo YH, Halcrow S, Brophy B, Scott G, Manavis J, Swift J, Blumbergs PC: The 'rosette-forming glioneuronal tumor' of the fourth ventricle. Neuropathology; 2009 Jun;29(3):309-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Neoplasms, Neuroepithelial / pathology
  • [MeSH-minor] Adult. Astrocytoma / metabolism. Astrocytoma / pathology. Astrocytoma / radiography. Brain / metabolism. Brain / pathology. Brain / surgery. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Microscopy, Electron. Synaptophysin / metabolism. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18647265.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Synaptophysin
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57. Gil-Salú JL, Nieto A, Rodríguez-Gutiérrez JF, Almarcha J: [Allelic loss at 1p/19q analysis in brain tumors of glial lineage]. Neurocirugia (Astur); 2007 Aug;18(4):285-93; discussion 293
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  • BACKGROUND: To analyze in cerebral tumors of neuroepithelial tissue 1p/19q codeletions by study of loss of heterozygosity (LOH).
  • METHODS: We aimed to determine several deletions mapping 1p and 19q chromosomes, three allelic loss of 1p and two allelic loss of 19q, in patients with cerebral tumors which were operated in our Department from October 2004 until March 2006.
  • RESULTS: Were included in the first part of this study 45 sample of neuroepithelial tissue supratentorial tumors: 29 glioblastoma, 1 gliosarcoma, 7 diffuse astrocytoma grade II, 1 oligoastrocytoma, 3 oligodendroglioma, 1 anaplastic oligodendroglioma, 1 xanthoastrocytoma, 1 dysembryoplastic neuroepithelial tumour and 1 pilocytic astrocytoma.
  • 80% of oligodendroglial tumors, 14% glioblastoma and 14% of diffuse astrocytoma grade II.

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  • (PMID = 17882335.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Genetic Markers
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58. Habek M, Brinar VV, Rados M, Zadro I, Zarković K: Brain MRI abnormalities in ataxia-telangiectasia. Neurologist; 2008 May;14(3):192-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / pathology. Ataxia Telangiectasia / pathology. Brain / abnormalities. Brain / pathology. Brain Neoplasms / pathology
  • [MeSH-minor] Adult. Age Factors. Atrophy / pathology. Atrophy / physiopathology. Cerebellar Diseases / etiology. Cerebellar Diseases / pathology. Cerebellar Diseases / physiopathology. Cerebral Arteries / pathology. Cerebral Arteries / physiopathology. Disease Progression. Fatal Outcome. Female. Humans. Magnetic Resonance Imaging. Telangiectasis / genetics. Telangiectasis / pathology. Telangiectasis / physiopathology. Tomography, X-Ray Computed


59. Carvalho-Neto Ad, Bruck I, Antoniuk SA, Marchiori E, Gasparetto EL: Proton MR spectroscopy of the foramen of Monro region in patients with tuberous sclerosis complex. Arq Neuropsiquiatr; 2008 Jun;66(2B):303-7
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  • [MeSH-major] Amino Acids / metabolism. Cerebral Ventricle Neoplasms / metabolism. Cerebral Ventricles / metabolism. Choline / metabolism. Magnetic Resonance Spectroscopy / methods. Tuberous Sclerosis / metabolism
  • [MeSH-minor] Aspartic Acid / analogs & derivatives. Aspartic Acid / analysis. Astrocytoma / diagnosis. Astrocytoma / metabolism. Basal Ganglia / metabolism. Biomarkers, Tumor / metabolism. Brain Chemistry. Case-Control Studies. Child. Creatine / analysis. Early Detection of Cancer. Female. Follow-Up Studies. Humans. Male. Prospective Studies. Protons

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  • (PMID = 18641860.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Amino Acids; 0 / Biomarkers, Tumor; 0 / Protons; 30KYC7MIAI / Aspartic Acid; 997-55-7 / N-acetylaspartate; MU72812GK0 / Creatine; N91BDP6H0X / Choline
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60. Holveck A, Grand S, Boini S, Kirchin M, Le Bas JF, Dietemann JL, Bracard S, Kremer S: Dynamic susceptibility contrast-enhanced MRI evaluation of cerebral intraventricular tumors: preliminary results. J Neuroradiol; 2010 Dec;37(5):269-75
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  • [Title] Dynamic susceptibility contrast-enhanced MRI evaluation of cerebral intraventricular tumors: preliminary results.
  • METHODS: A total of 28 patients with intraventricular tumors (five meningiomas, five papillomas, three ependymomas, four subependymomas, seven central neurocytomas, two subependymal giant cell astrocytomas and two metastases) underwent conventional and dynamic susceptibility contrast-enhanced MRI.
  • Cerebral blood volume (CBV) maps were obtained and the relative CBV (rCBV) calculated for each tumor.
  • CONCLUSION: Susceptibility contrast-enhanced MRI can provide additional information on the vascularization of intraventricular cerebral tumors and may help in making the differential diagnosis.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology. Ependymoma / pathology. Magnetic Resonance Imaging / methods. Meningioma / pathology. Neurocytoma / pathology. Papilloma / pathology

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20435349.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
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61. Yang WD, Wang ZG, Zhang Q, Pu PY, Yu Q, Yang SY, Zhang JN, Yue SY, Sun J: [Stereotactic resection of small intracerebral lesions in motor cortex using blood oxygen level depended functional magnetic resonance imaging and diffusion tensor imaging fusion guidance]. Zhonghua Yi Xue Za Zhi; 2008 Oct 28;88(39):2763-6
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  • Histological examination showed 3 cases of meningeoma, 3 cases of astrocytoma of grade II, 2 cases of astrocytoma of grade III, 2 cases of abscess, and 2 cases of cavernous angioma.
  • [MeSH-major] Brain Diseases / surgery. Cerebral Cortex / surgery. Stereotaxic Techniques

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  • (PMID = 19080451.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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62. Suzuki M, Suzuki M, Nakayama J, Suzuki A, Angata K, Chen S, Sakai K, Hagihara K, Yamaguchi Y, Fukuda M: Polysialic acid facilitates tumor invasion by glioma cells. Glycobiology; 2005 Sep;15(9):887-94
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  • In this study, we first revealed that among patients with glioma, PSA was detected more frequently in diffuse astrocytoma cells, which spread extensively.
  • [MeSH-major] Astrocytoma / metabolism. Astrocytoma / pathology. Cerebral Ventricle Neoplasms / metabolism. Cerebral Ventricle Neoplasms / pathology. Neural Cell Adhesion Molecules / metabolism. Sialic Acids / metabolism

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  • (PMID = 15872150.001).
  • [ISSN] 0959-6658
  • [Journal-full-title] Glycobiology
  • [ISO-abbreviation] Glycobiology
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA33895; United States / NINDS NIH HHS / NS / R01 NS41332
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecules; 0 / Sialic Acids; 0 / polysialic acid
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63. Kutlay M, Simşek H, Colak A, Demircan MN: Balloon compression technique in the management of persistent intraoperative intratumoral hemorrhage resulting from stereotactic biopsy: technical note. Neurosurgery; 2010 Jun;66(6 Suppl Operative):334-5; discussion 335
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  • [MeSH-major] Balloon Occlusion / methods. Biopsy / adverse effects. Brain Neoplasms / pathology. Cerebral Hemorrhage / surgery. Postoperative Hemorrhage / surgery. Stereotaxic Techniques / adverse effects
  • [MeSH-minor] Adult. Aged. Astrocytoma / blood supply. Astrocytoma / pathology. Astrocytoma / physiopathology. Catheterization / instrumentation. Catheterization / methods. Female. Fluoroscopy / methods. Glioma / blood supply. Glioma / pathology. Glioma / physiopathology. Humans. Male. Middle Aged. Neuronavigation / methods. Treatment Outcome. Young Adult

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  • (PMID = 20489527.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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64. Jung CS, Foerch C, Schänzer A, Heck A, Plate KH, Seifert V, Steinmetz H, Raabe A, Sitzer M: Serum GFAP is a diagnostic marker for glioblastoma multiforme. Brain; 2007 Dec;130(Pt 12):3336-41
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  • A serum marker for malignant cerebral astrocytomas could improve both differential diagnosis and clinical management of brain tumour patients.
  • To evaluate whether the serum concentration of glial fibrillary acidic protein (GFAP) may indicate glioblastoma multiforme (GBM) in patients with single supratentorial space-occupying lesions, we prospectively examined 50 consecutive patients with histologically proven GBM, World Health Organization (WHO) grade IV, 14 patients with anaplastic astrocytoma (WHO grade III), 4 patients with anaplastic oligodendroglioma, 13 patients with diffuse astrocytoma (WHO grade II), 17 patients with a single cerebral metastasis and 50 healthy controls.

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  • (PMID = 17998256.001).
  • [ISSN] 1460-2156
  • [Journal-full-title] Brain : a journal of neurology
  • [ISO-abbreviation] Brain
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Neoplasm Proteins
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65. Jalali R, Mallick I, Dutta D, Goswami S, Gupta T, Munshi A, Deshpande D, Sarin R: Factors influencing neurocognitive outcomes in young patients with benign and low-grade brain tumors treated with stereotactic conformal radiotherapy. Int J Radiat Oncol Biol Phys; 2010 Jul 15;77(4):974-9
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  • METHODS AND MATERIALS: Twenty-eight patients (median age, 13 years) with residual/progressive brain tumors (10 craniopharyngioma, 8 cerebellar astrocytoma, 6 optic pathway glioma and 4 cerebral low-grade glioma) were treated with SCRT to a dose of 54 Gy in 30 fractions over 6 weeks.
  • [MeSH-minor] Adolescent. Astrocytoma / radiotherapy. Cerebellar Neoplasms / psychology. Cerebellar Neoplasms / radiotherapy. Child. Cognition / radiation effects. Craniopharyngioma / psychology. Craniopharyngioma / radiotherapy. Female. Humans. Male. Optic Nerve Glioma / radiotherapy. Prospective Studies. Radiotherapy, Conformal / methods. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19864079.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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66. Feigl GC, Ritz R, Moraes M, Klein J, Ramina K, Gharabaghi A, Krischek B, Danz S, Bornemann A, Liebsch M, Tatagiba MS: Resection of malignant brain tumors in eloquent cortical areas: a new multimodal approach combining 5-aminolevulinic acid and intraoperative monitoring. J Neurosurg; 2010 Aug;113(2):352-7
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  • [MeSH-major] Aminolevulinic Acid. Brain Neoplasms / surgery. Cerebral Cortex / surgery. Glioblastoma / surgery. Monitoring, Intraoperative / methods. Photosensitizing Agents
  • [MeSH-minor] Adult. Aged. Astrocytoma / pathology. Astrocytoma / surgery. Astrocytoma / therapy. Combined Modality Therapy. Diffusion Tensor Imaging. Female. Fluorescence. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neural Pathways / pathology. Neural Pathways / physiology. Neural Pathways / surgery. Neuronavigation. Oligodendroglioma / pathology. Oligodendroglioma / surgery. Oligodendroglioma / therapy. Prospective Studies. Treatment Outcome

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  • (PMID = 19911888.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 88755TAZ87 / Aminolevulinic Acid
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67. Kim SJ, Jeong HJ, Kim BK, Kim NH, Kim JS, Choi KS, Lee HJ, Kang ST, Shin SS, Kim WI, Eom HS, Lee KM, Um JY, Hong SH, Kim HM: Anti-inflammatory effect of jeongshintang through suppression of p38 activation in human astrocytoma, U373MG cells. Exp Mol Pathol; 2006 Aug;81(1):85-91
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  • [Title] Anti-inflammatory effect of jeongshintang through suppression of p38 activation in human astrocytoma, U373MG cells.
  • Jeongshintang (JST) is a Korean herbal prescription, which has been successfully used for cerebral diseases.
  • [MeSH-minor] Amyloid beta-Peptides / toxicity. Astrocytoma. Cell Line, Tumor. Cyclooxygenase 2. Dinoprostone / antagonists & inhibitors. Enzyme Activation / drug effects. Humans. Interleukin-1 / toxicity. Interleukin-6 / antagonists & inhibitors. Interleukin-8 / antagonists & inhibitors. Membrane Proteins / antagonists & inhibitors. Peptide Fragments / toxicity. Protein Kinase Inhibitors / pharmacology

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  • (PMID = 16698013.001).
  • [ISSN] 0014-4800
  • [Journal-full-title] Experimental and molecular pathology
  • [ISO-abbreviation] Exp. Mol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amyloid beta-Peptides; 0 / Anti-Inflammatory Agents; 0 / Interleukin-1; 0 / Interleukin-6; 0 / Interleukin-8; 0 / Membrane Proteins; 0 / Neuroprotective Agents; 0 / Peptide Fragments; 0 / Plant Extracts; 0 / Protein Kinase Inhibitors; 0 / amyloid beta-protein (1-42); 0 / jeongshintang; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases; K7Q1JQR04M / Dinoprostone
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68. Tanaka S, Kobayashi I, Utsuki S, Iwamoto K, Takanashi J: Biopsy of brain stem glioma using motor-evoked potential mapping by direct peduncular stimulation and individual adjuvant therapy. Case report. Neurol Med Chir (Tokyo); 2005 Jan;45(1):49-55
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  • Serial magnetic resonance imaging showed an intrinsic diffuse brain stem glioma that gradually localized to the left cerebral peduncle after initial adjuvant therapy.
  • MEPs were only recorded from the left extremities even with left cerebral peduncular stimulation.
  • The histological diagnosis was anaplastic astrocytoma.
  • [MeSH-major] Astrocytoma / surgery. Brain Mapping. Brain Stem Neoplasms / surgery. Evoked Potentials, Motor. Mesencephalon / physiopathology. Neurosurgical Procedures / methods

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  • (PMID = 15699622.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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69. Cha S, Tihan T, Crawford F, Fischbein NJ, Chang S, Bollen A, Nelson SJ, Prados M, Berger MS, Dillon WP: Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging. AJNR Am J Neuroradiol; 2005 Feb;26(2):266-73
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  • [Title] Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging.
  • The purpose of our study was to investigate dynamic susceptibility contrast-enhanced (DSC) MR imaging characteristics of the two most common subtypes of low-grade infiltrating glioma: astrocytoma and oligodendroglioma.
  • METHODS: We studied 25 consecutive patients with treatment-naive, histopathologically confirmed World Health Organization grade II astrocytoma (n = 11) or oligodendroglioma (n = 14).
  • Anatomic MR images were analyzed for morphologic features, and DSC MR data were processed to yield quantitative cerebral blood volume (CBV) measurements.
  • RESULTS: The maximum relative CBV (rCBV(max)) in tumor ranged from 0.48 to 1.34 (0.92 +/- 0.27, median +/- SD) in astrocytomas and from 1.29 to 9.24 (3.68 +/- 2.39) in oligodendrogliomas.
  • CONCLUSION: The tumor rCBV(max) measurements derived from DSC MR imaging were significantly higher in low-grade oligodendrogliomas than in astrocytomas.

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  • (PMID = 15709123.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / K23 NS 45013
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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70. Reisch R, Stadie A, Kockro R, Gawish I, Schwandt E, Hopf N: The minimally invasive supraorbital subfrontal key-hole approach for surgical treatment of temporomesial lesions of the dominant hemisphere. Minim Invasive Neurosurg; 2009 Aug;52(4):163-9
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  • Pathological investigation showed 7 low-grade astrocytomas, 4 high-grade astrocytomas, 2 gangliogliomas and 2 cavernomas.
  • [MeSH-minor] Adult. Astrocytoma / pathology. Astrocytoma / surgery. Dominance, Cerebral / physiology. Female. Frontal Lobe / anatomy & histology. Frontal Lobe / surgery. Ganglioglioma / pathology. Ganglioglioma / surgery. Hemangioma, Cavernous, Central Nervous System / pathology. Hemangioma, Cavernous, Central Nervous System / surgery. Hippocampus / pathology. Hippocampus / surgery. Humans. Male. Middle Aged. Orbit / anatomy & histology. Orbit / surgery. Parahippocampal Gyrus / pathology. Parahippocampal Gyrus / surgery. Postoperative Complications / etiology. Postoperative Complications / prevention & control. Preoperative Care. Treatment Outcome. Young Adult

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  • [Copyright] Georg Thieme Verlag KG Stuttgart * New York.
  • (PMID = 19838969.001).
  • [ISSN] 1439-2291
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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71. Kamada K, Takeuchi F, Kuriki S, Todo T, Morita A, Sawamura Y: Dissociated expressive and receptive language functions on magnetoencephalography, functional magnetic resonance imaging, and amobarbital studies. Case report and review of the literature. J Neurosurg; 2006 Apr;104(4):598-607
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  • [MeSH-major] Amobarbital. Astrocytoma / physiopathology. Brain Mapping / methods. Brain Neoplasms / physiopathology. Dominance, Cerebral / physiology. Frontal Lobe / physiology. Magnetic Resonance Imaging. Magnetoencephalography. Reading. Speech Perception / physiology. Temporal Lobe / physiology. Verbal Behavior / physiology

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  • [CommentIn] J Neurosurg. 2007 Apr;106(4):726-7; author reply 727-8 [17432730.001]
  • (PMID = 16619665.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] GWH6IJ239E / Amobarbital
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72. Reis F, Faria AV, Zanardi VA, Menezes JR, Cendes F, Queiroz LS: Neuroimaging in pineal tumors. J Neuroimaging; 2006 Jan;16(1):52-8
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  • BACKGROUND AND PURPOSE: The authors report radiological findings in 11 tumors in the pineal region, which were histologically diagnosed as germinomas, pineocytomas pineoblastomas, ependymomas, teratomas, and astrocytomas.
  • Extension to adjacent structures occurred in five patients and spread through the cerebral spinal fluid (CSF) in two.
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / diagnosis. Child. Diagnosis, Differential. Ependymoma / diagnosis. Female. Germinoma / diagnosis. Humans. Magnetic Resonance Imaging. Male. Neuroblastoma / diagnosis. Prognosis. Teratoma / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 16483277.001).
  • [ISSN] 1051-2284
  • [Journal-full-title] Journal of neuroimaging : official journal of the American Society of Neuroimaging
  • [ISO-abbreviation] J Neuroimaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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73. Brat DJ, Scheithauer BW, Fuller GN, Tihan T: Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. Brain Pathol; 2007 Jul;17(3):319-24
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  • [Title] Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma.
  • Three new tumours, angiocentric glioma (AG), pilomyxoid astrocytoma (PMA), and pituicytoma are added to the section on gliomas.
  • AG is a slowly growing cerebral tumour that typically presents with seizures in children and young adults.
  • While PMA is considered a more aggressive variant of pilocytic astrocytoma, this relationship awaits further clarification.
  • [MeSH-major] Astrocytoma / classification. Central Nervous System Neoplasms / classification. Glioma / classification. Neuroglia / pathology. Pituitary Gland / pathology. Pituitary Neoplasms / classification. World Health Organization

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  • (PMID = 17598825.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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74. Aronica E, Gorter JA, Redeker S, van Vliet EA, Ramkema M, Scheffer GL, Scheper RJ, van der Valk P, Leenstra S, Baayen JC, Spliet WG, Troost D: Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain. Epilepsia; 2005 Jun;46(6):849-57
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  • METHODS: Several epileptogenic pathologies, such as hippocampal sclerosis (HS), focal cortical dysplasia (FCD), dysembryoplastic neuroepithelial tumor, oligodendroglioma astrocytoma, and glioblastoma multiforme were studied by using Western blot and immunocytochemistry.
  • The higher expression observed in astrocytomas by Western blot analysis was related to the higher vascular density within the tumor tissue.
  • [MeSH-minor] ATP Binding Cassette Transporter, Sub-Family G, Member 2. Astrocytoma / chemistry. Blotting, Western. Cerebral Cortex / abnormalities. Cerebral Cortex / chemistry. Cerebral Cortex / metabolism. Hippocampus / metabolism. Hippocampus / pathology. Humans. Immunohistochemistry. Microcirculation. Oligodendroglioma / chemistry. Oligodendroglioma / metabolism. Sclerosis. Tissue Distribution

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  • (PMID = 15946326.001).
  • [ISSN] 0013-9580
  • [Journal-full-title] Epilepsia
  • [ISO-abbreviation] Epilepsia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ABCG2 protein, human; 0 / ATP Binding Cassette Transporter, Sub-Family G, Member 2; 0 / ATP-Binding Cassette Transporters; 0 / Multidrug Resistance-Associated Proteins; 0 / Neoplasm Proteins
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75. Beppu T, Inoue T, Nishimoto H, Ogasawara K, Ogawa A, Sasaki M: Preoperative imaging of superficially located glioma resection using short inversion-time inversion recovery images in high-field magnetic resonance imaging. Clin Neurol Neurosurg; 2007 May;109(4):327-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / diagnosis. Astrocytoma / surgery. Brain Neoplasms / diagnosis. Brain Neoplasms / surgery. Cerebral Cortex / pathology. Image Enhancement / methods. Image Processing, Computer-Assisted / methods. Magnetic Resonance Imaging / methods. Oligodendroglioma / diagnosis
  • [MeSH-minor] Adult. Aged. Brain Edema / diagnosis. Brain Edema / surgery. Corpus Callosum / pathology. Corpus Callosum / surgery. Dominance, Cerebral / physiology. Female. Frontal Lobe / pathology. Frontal Lobe / surgery. Gyrus Cinguli / pathology. Gyrus Cinguli / surgery. Humans. Male. Middle Aged. Occipital Lobe / pathology. Occipital Lobe / surgery. Parietal Lobe / pathology. Parietal Lobe / surgery. Postoperative Complications / diagnosis. Preoperative Care. Sensitivity and Specificity

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  • (PMID = 17275995.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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76. Roopesh Kumar SV, Mohanty A, Santosh V, Satish S, Devi BI, Praharaj SS, Kolluri SV: Endoscopic options in management of posterior third ventricular tumors. Childs Nerv Syst; 2007 Oct;23(10):1135-45
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  • A positive biopsy was obtained in all the patients (pinealocytoma 4, pinealoblastoma 10, embryonal cell carcinoma 1, germinoma 2, oligodendroglioma 1, astrocytoma 2, tuberculoma 4).
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Endoscopy. Neurosurgical Procedures. Third Ventricle / pathology

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  • (PMID = 17541605.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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77. Ramonet D, de Yebra L, Fredriksson K, Bernal F, Ribalta T, Mahy N: Similar calcification process in acute and chronic human brain pathologies. J Neurosci Res; 2006 Jan;83(1):147-56
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  • Insofar as calcium precipitation reduces activity signals at no energy expense, the presence in human and rodent cerebral brain lesions of a common pattern of calcification may reflect an imbalance between cellular signals of activity and energy availability for its execution.
  • [MeSH-minor] Acute Disease. Adult. Aged. Aged, 80 and over. Alzheimer Disease / pathology. Animals. Astrocytoma / pathology. Brain Injuries / complications. Brain Injuries / pathology. Brain Neoplasms / pathology. Calcium / metabolism. Chronic Disease. Dementia, Vascular / pathology. Epilepsy / etiology. Epilepsy / pathology. Female. Humans. Lewy Body Disease / pathology. Male. Mice. Middle Aged. Parkinson Disease / pathology

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  • (PMID = 16323208.001).
  • [ISSN] 0360-4012
  • [Journal-full-title] Journal of neuroscience research
  • [ISO-abbreviation] J. Neurosci. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] SY7Q814VUP / Calcium
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78. RamachandranNair R, Ochi A, Akiyama T, Buckley DJ, Soman TB, Weiss SK, Otsubo H: Partial seizures triggering infantile spasms in the presence of a basal ganglia glioma. Epileptic Disord; 2005 Dec;7(4):378-82
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  • [MeSH-major] Astrocytoma / complications. Corpus Striatum / pathology. Epilepsies, Partial / etiology. Globus Pallidus / pathology. Spasms, Infantile / etiology. Supratentorial Neoplasms / complications
  • [MeSH-minor] Anticonvulsants / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cerebral Cortex / pathology. Cerebral Cortex / physiopathology. Developmental Disabilities / etiology. Electroencephalography. Humans. Infant. Paresis / etiology

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  • (PMID = 16338683.001).
  • [ISSN] 1294-9361
  • [Journal-full-title] Epileptic disorders : international epilepsy journal with videotape
  • [ISO-abbreviation] Epileptic Disord
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Anticonvulsants
  • [Number-of-references] 20
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79. Lucio-Eterovic AK, Cortez MA, Valera ET, Motta FJ, Queiroz RG, Machado HR, Carlotti CG Jr, Neder L, Scrideli CA, Tone LG: Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas. BMC Cancer; 2008;8:243
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  • [Title] Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas.
  • The purpose of this study was to evaluate and compare mRNA and protein levels of class I, II and IV of HDACs in low grade and high grade astrocytomas and normal brain tissue and to correlate the findings with the malignancy in astrocytomas.
  • Eleven normal cerebral tissue samples were also analyzed (54 total samples analyzed).
  • RESULTS: We found that mRNA levels of class II and IV HDACs were downregulated in glioblastomas compared to low-grade astrocytomas and normal brain tissue (7 in 8 genes, p < 0.05).
  • The protein levels of class II HDAC9 were also lower in high-grade astrocytomas than in low-grade astrocytomas and normal brain tissue.
  • [MeSH-major] Astrocytoma / enzymology. Brain / enzymology. Brain Neoplasms / enzymology. Gene Expression Regulation, Enzymologic. Gene Expression Regulation, Neoplastic. Glioblastoma / enzymology. Histone Deacetylases / biosynthesis

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  • (PMID = 18713462.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiation-Sensitizing Agents; EC 3.5.1.98 / Histone Deacetylases
  • [Other-IDs] NLM/ PMC2536671
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80. Ariës MJ, Vroomen PC, van der Hoeven JH, De Keyser J: Trismus as manifestation of bilateral internal capsule genu infarction. Clin Neurol Neurosurg; 2008 Mar;110(3):305-6
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  • [MeSH-major] Cerebral Infarction / complications. Trismus / etiology
  • [MeSH-minor] Adult. Astrocytoma / complications. Brain Neoplasms / complications. Diffusion Magnetic Resonance Imaging. Electroencephalography. Humans. Hydrocephalus / pathology. Male. Muscle Weakness / etiology. Thalamic Diseases / complications

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  • (PMID = 18187255.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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81. Braoudaki M, Tsangaris GT, Karamolegou K, Anagnostopoulos AK, Prodromou N, Tzortzatou-Stathopoulou F: Proteomic profile of a therapy related acute myeloid leukemia following brain tumor. Leuk Lymphoma; 2010 Dec;51(12):2306-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Astrocytoma / drug therapy. Astrocytoma / metabolism. Carcinoma, Small Cell / drug therapy. Carcinoma, Small Cell / metabolism. Child, Preschool. Female. Humans. Metabolome. Proteomics


82. Perez-Saldana MT, Vilar C, Geffner-Sclarsky D, Belenguer-Benavides A, Del Villar-Igea A, Gil-Fortuno M, Bahamonde D: [Meningoencephalomyelitis as the initial symptom of a brain tumour mimicking encephalitis due to herpes simplex virus: a case report]. Rev Neurol; 2007 Mar 16-31;44(6):348-52
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  • [Transliterated title] Meningoencefalomielitis como manifestacion inicial de un tumor cerebral que imita una encefalitis por virus del herpes simple: descripcion de un caso.
  • The post-mortem examination revealed a grade III oligoastrocytoma in both temporal lobes, which had extended into the adjacent subarachnoid space and the cerebral and cervical leptomeninges.
  • [MeSH-major] Astrocytoma. Brain Neoplasms. Encephalitis, Herpes Simplex / etiology. Meninges / pathology. Meningitis / etiology


83. Anan M, Inoue R, Ishii K, Abe T, Fujiki M, Kobayashi H, Goya T, Nakazato Y: A rosette-forming glioneuronal tumor of the spinal cord: the first case of a rosette-forming glioneuronal tumor originating from the spinal cord. Hum Pathol; 2009 Jun;40(6):898-901
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  • The astrocytic component showed characteristic features of a pilocytic astrocytoma, as is often the case in the fourth ventricle examples.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology. Spinal Cord / pathology. Spinal Cord Neoplasms / pathology
  • [MeSH-minor] Adult. Astrocytoma / pathology. Female. Humans. Rosette Formation

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  • [CommentIn] Hum Pathol. 2009 Oct;40(10):1510; author reply 1510 [19616823.001]
  • (PMID = 19269010.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Wang Y, Xiong J, Chu SG, Liu Y, Cheng HX, Wang YF, Zhao Y, Mao Y: Rosette-forming glioneuronal tumor: report of an unusual case with intraventricular dissemination. Acta Neuropathol; 2009 Dec;118(6):813-9
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  • Histological examination demonstrated two regions characterized by predominant neurocytic rosettes and scant low grade astrocytoma.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology. Ganglioglioma / pathology

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  • (PMID = 19585134.001).
  • [ISSN] 1432-0533
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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85. Di Costanzo A, Pollice S, Trojsi F, Giannatempo GM, Popolizio T, Canalis L, Armillotta M, Maggialetti A, Carriero A, Tedeschi G, Scarabino T: Role of perfusion-weighted imaging at 3 Tesla in the assessment of malignancy of cerebral gliomas. Radiol Med; 2008 Feb;113(1):134-43
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  • [Title] Role of perfusion-weighted imaging at 3 Tesla in the assessment of malignancy of cerebral gliomas.
  • PWI was performed by first-pass gadopentetate dimeglumine T2*-weighted echo-planar images, and cerebral blood volume (CBV) maps were computed with a nondiffusible tracer model.
  • It enhances the magnetic resonance (MR) assessment of cerebral gliomas and provides useful information for planning surgical and radiation treatment.
  • [MeSH-minor] Adult. Aged. Astrocytoma / diagnosis. Blood Volume / physiology. Brain Edema / diagnosis. Cerebrovascular Circulation / physiology. Contrast Media. Diagnosis, Differential. Echo-Planar Imaging / methods. Female. Gadolinium DTPA. Ganglioglioma / diagnosis. Glioblastoma / diagnosis. Humans. Image Enhancement / methods. Male. Middle Aged. Necrosis. Oligodendroglioma / diagnosis. Retrospective Studies

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  • (PMID = 18338133.001).
  • [ISSN] 0033-8362
  • [Journal-full-title] La Radiologia medica
  • [ISO-abbreviation] Radiol Med
  • [Language] eng; ita
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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86. Fu JB, Parsons HA, Shin KY, Guo Y, Konzen BS, Yadav RR, Smith DW: Comparison of functional outcomes in low- and high-grade astrocytoma rehabilitation inpatients. Am J Phys Med Rehabil; 2010 Mar;89(3):205-12
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  • [Title] Comparison of functional outcomes in low- and high-grade astrocytoma rehabilitation inpatients.
  • OBJECTIVES: To compare inpatient rehabilitation outcomes between patients with low- and high-grade astrocytoma.
  • A high-grade (21 of 443 patients) and low-grade astrocytoma (21 of 24 patients) group were matched on three of five criteria in the order of importance: area of brain involvement (divided into left cerebral, right cerebral, midline and/or bilateral cerebral, and infratentorial), single vs. multiple intracranial neurosurgical procedures, age (within 10 yrs), period of rehabilitation admission (within 3 yrs), and sex.
  • The high-grade group had significantly (P < 0.05) higher total gain and longer stay in inpatient rehabilitation (mean +/- standard deviation, 21.7 +/- 10.1 vs. 13.0 +/- 9.3 and 13 +/- 7.1 day vs. 9 +/- 6.2 days, respectively) than did the low-grade astrocytoma group.
  • CONCLUSIONS: Compared with patients with low-grade astrocytoma, patients with high-grade astrocytoma had higher total functional independence measure gain but also longer lengths of stay.

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  • (PMID = 20068429.001).
  • [ISSN] 1537-7385
  • [Journal-full-title] American journal of physical medicine & rehabilitation
  • [ISO-abbreviation] Am J Phys Med Rehabil
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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87. Salvati M, D'Elia A, Melone GA, Brogna C, Frati A, Raco A, Delfini R: Radio-induced gliomas: 20-year experience and critical review of the pathology. J Neurooncol; 2008 Sep;89(2):169-77
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  • The authors report their personal experience with a surgical series of 16 cases of cerebral radiation-induced gliomas, defining diagnostic criteria and surgical and clinical characteristics.
  • There were 14 cases of glioblastoma (grade IV WHO) and 2 cases of astrocytoma (grade II WHO), with a mean latency time of 17 years (range: 6-26 years).

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  • (PMID = 18566750.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Walmsley GL, Chandler K, Davies ES, Lamb CR, Smyth B, Summers BA: Multi-focal cerebral oligoastrocytoma in a puppy. J Small Anim Pract; 2009 Aug;50(8):435-9
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  • [Title] Multi-focal cerebral oligoastrocytoma in a puppy.
  • Magnetic resonance imaging identified multiple, large lesions involving both cerebral hemispheres.
  • [MeSH-major] Astrocytoma / veterinary. Brain Neoplasms / veterinary. Neoplasms, Multiple Primary / veterinary

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  • (PMID = 19689673.001).
  • [ISSN] 1748-5827
  • [Journal-full-title] The Journal of small animal practice
  • [ISO-abbreviation] J Small Anim Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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89. Faber-Zuschratter H, Hüttmann K, Steinhäuser C, Becker A, Schramm J, Okafo U, Shanley D, Yilmazer-Hanke DM: Ultrastructural and functional characterization of satellitosis in the human lateral amygdala associated with Ammon's horn sclerosis. Acta Neuropathol; 2009 May;117(5):545-55
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  • Non-AHS cases suffered from ganglioglioma, cortical dysplasia, Sturge-Weber syndrome, astrocytoma WHO III-IV, Rasmussen's encephalitis, cerebral infarction and perinatal brain damage.

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  • (PMID = 19247679.001).
  • [ISSN] 1432-0533
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens; 0 / Proteoglycans; 0 / chondroitin sulfate proteoglycan 4; EC 4.1.1.15 / Glutamate Decarboxylase
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90. Haris M, Husain N, Singh A, Husain M, Srivastava S, Srivastava C, Behari S, Rathore RK, Saksena S, Gupta RK: Dynamic contrast-enhanced derived cerebral blood volume correlates better with leak correction than with no correction for vascular endothelial growth factor, microvascular density, and grading of astrocytoma. J Comput Assist Tomogr; 2008 Nov-Dec;32(6):955-65
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  • [Title] Dynamic contrast-enhanced derived cerebral blood volume correlates better with leak correction than with no correction for vascular endothelial growth factor, microvascular density, and grading of astrocytoma.
  • OBJECTIVE: To look for the impact of leak correction on correlation of perfusion indices with microvessel density (MVD) and vascular endothelial growth factor (VEGF) in astrocytomas.
  • METHODS: Dynamic contrast-enhanced magnetic resonance imaging was performed in 64 patients with varying grades of astrocytoma.
  • Perfusion indices (ie, relative cerebral blood volume (rCBV) with and without leak correction, relative cerebral blood flow (rCBF), permeability (k(trans)), and leakage (v(e)) were quantified.
  • RESULTS: Perfusion indices showed significant difference among the astrocytoma grades.
  • The corrected rCBV discriminated 100% low-grade from high-grade astrocytoma, while uncorrected rCBV did this in 95.5% low-grade and 71.4% high-grade astrocytoma.
  • CONCLUSIONS: Corrected rCBV better correlates with grade and is more accurate in discriminating low-grade from high-grade astrocytoma compared with uncorrected rCBV.
  • [MeSH-major] Artifacts. Astrocytoma / pathology. Brain Neoplasms / diagnosis. Brain Neoplasms / metabolism. Gadolinium DTPA. Image Interpretation, Computer-Assisted / methods. Magnetic Resonance Imaging / methods. Vascular Endothelial Growth Factor A / analysis

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  • (PMID = 19204461.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Vascular Endothelial Growth Factor A; K2I13DR72L / Gadolinium DTPA
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91. Schittenhelm J, Psaras T: Glioblastoma with granular cell astrocytoma features: a case report and literature review. Clin Neuropathol; 2010 Sep-Oct;29(5):323-9
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  • [Title] Glioblastoma with granular cell astrocytoma features: a case report and literature review.
  • The resected tumor showed histological features of a glioblastoma with granular cell astrocytoma features, lacking amplification of the EGFR gene region and IDH1R132H mutation.
  • Literature review of 59 cases showed a 12-month overall survival of 11.7% for high-grade and 40% for low-grade granular cell astrocytomas.
  • In 35% more than one cerebral lobe was affected.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Glioblastoma / pathology


92. Stavrinou LC, Boviatsis EJ: Medicine is a constant battlefield. Acta Neurochir (Wien); 2007 Jun;149(6):639-40
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  • [MeSH-minor] Adult. Astrocytoma / diagnosis. Astrocytoma / pathology. Biopsy. Brain / pathology. Brain Neoplasms / diagnosis. Brain Neoplasms / pathology. Clinical Competence. Diagnostic Errors. Diffuse Cerebral Sclerosis of Schilder / diagnosis. Diffuse Cerebral Sclerosis of Schilder / pathology. Female. Humans. Review Literature as Topic


93. Yamamoto T, Kato Y, Kawaguchi-Niida M, Shibata N, Osawa M, Saito K, Kröger S, Kobayashi M: Characteristics of neurons and glia in the brain of Fukuyama type congenital muscular dystrophy. Acta Myol; 2008 Jul;27:9-13
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  • Slight accumulation of N(epsilon)-(carboxymethyl)lysine, an oxidative modification product, is observed in astrocytes of Fukuyama type congenital muscular dystrophy and in an astrocytoma cell line with suppressed fukutin expression.
  • Cerebral cortical neurons of Fukuyama type congenital muscular dystrophy and controls react with an antibody for core alpha-dystroglycan but not with an antibody for glycosylated alpha-dystroglycan.

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  • (PMID = 19108571.001).
  • [ISSN] 1128-2460
  • [Journal-full-title] Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology
  • [ISO-abbreviation] Acta Myol
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / FKTN protein, human; 0 / Membrane Proteins; 5746-04-3 / N(6)-carboxymethyllysine; K3Z4F929H6 / Lysine
  • [Number-of-references] 22
  • [Other-IDs] NLM/ PMC2859607
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94. Ris MD, Beebe DW, Armstrong FD, Fontanesi J, Holmes E, Sanford RA, Wisoff JH, Children's Oncology Group: Cognitive and adaptive outcome in extracerebellar low-grade brain tumors in children: a report from the Children's Oncology Group. J Clin Oncol; 2008 Oct 10;26(29):4765-70
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  • PURPOSE: To determine whether pediatric patients treated with surgery only for low-grade tumors in the cerebral hemispheres, supratentorial midline, and exophytic brainstem evidence neurocognitive, academic, adaptive, or emotional/behavioral sequelae.
  • PATIENTS AND METHODS: Ninety-three patients from a natural history study of low-grade astrocytomas were tested an average of 111 days after surgery.
  • Patients with hemispheric, midline, and brainstem tumors did not differ significantly.
  • Moreover, these results suggest greater risk for patients with lesions situated in the left cerebral hemisphere.

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  • (PMID = 18779602.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA98543
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2653141
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95. Borrmann T, Abdelrahman A, Volpini R, Lambertucci C, Alksnis E, Gorzalka S, Knospe M, Schiedel AC, Cristalli G, Müller CE: Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J Med Chem; 2009 Oct 8;52(19):5974-89
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  • Functional evaluation of selected adenine derivatives in adenylate cyclase assays at 1321N1 astrocytoma cells stably expressing the rAde1R showed that all compounds investigated were agonists or partial agonists.
  • [MeSH-minor] Animals. Astrocytoma / pathology. Cell Line. Cell Line, Tumor. Cerebral Cortex / chemistry. Humans. Ligands. Protein Binding. Purinergic P1 Receptor Agonists. Purinergic P1 Receptor Antagonists. Rats. Structure-Activity Relationship

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  • (PMID = 19731917.001).
  • [ISSN] 1520-4804
  • [Journal-full-title] Journal of medicinal chemistry
  • [ISO-abbreviation] J. Med. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ligands; 0 / Purinergic P1 Receptor Agonists; 0 / Purinergic P1 Receptor Antagonists; 0 / Receptors, Purinergic P1; JAC85A2161 / Adenine; M351LCX45Y / Tubercidin
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96. Kumar AJ, Leeds NE, Kumar VA, Fuller GN, Lang FF, Milas Z, Weinberg JS, Ater JL, Sawaya R: Magnetic resonance imaging features of pilocytic astrocytoma of the brain mimicking high-grade gliomas. J Comput Assist Tomogr; 2010 Jul;34(4):601-11
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  • [Title] Magnetic resonance imaging features of pilocytic astrocytoma of the brain mimicking high-grade gliomas.
  • OBJECTIVE: The typical magnetic resonance/computed tomographic imaging appearance of pilocytic astrocytoma (PA) is that of a cyst with an intensely enhancing mural nodule.
  • Tumor locations consisted of the following: optic chiasm (22), lateral ventricle (3), thalamus (12), basal ganglia (1), cerebral hemisphere (10), corpus callosum (2), brain stem (26), fourth ventricle (1), and cerebellum (23).
  • CONCLUSIONS: It is important to recognize the aggressive imaging appearance of PA (grade 1 astrocytoma) because it can be mistaken for high-grade gliomas and may thus lead to inappropriate therapy.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Glioma / diagnosis. Magnetic Resonance Imaging / methods

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  • (PMID = 20657231.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article
  • [Publication-country] United States
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97. Oshiro S, Tsugu H, Komatsu F, Abe H, Onishi H, Ohmura T, Iwaasa M, Sakamoto S, Fukushima T: Quantitative assessment of gliomas by proton magnetic resonance spectroscopy. Anticancer Res; 2007 Nov-Dec;27(6A):3757-63
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  • PATIENTS AND METHODS: Eight patients with histologically verified gliomas, comprising 2 cases with glioblastoma multiforme (GBM, grade 4), 5 cases with anaplastic oligodendroglioma (AO, grade 3; high-grade glioma), and 1 case with fibrillary astrocytoma (FA, grade 2; low-grade glioma) were evaluated using the 1H-MRS protocol following conventional MR imaging, diffusion-weighted imaging (DWI), and perfusion-weighted imaging (PWI) preoperatively.
  • RESULTS: High-grade gliomas tended to demonstrate signal hyperintensity by DWI and higher relative cerebral blood volume (rCBV) by PWI.

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  • (PMID = 17970039.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Protons
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98. Wierzba-Bobrowicz T, Lewandowska E, Matyja E, Dziduszko J, Koszewski W, Stepień T, Błazejewska-Hyzorek B: Granular cell astrocytoma. A case report with immunohistochemical and ultrastructural characterization. Folia Neuropathol; 2008;46(4):286-93
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  • [Title] Granular cell astrocytoma. A case report with immunohistochemical and ultrastructural characterization.
  • Granular cell astrocytoma (GCA) is an uncommon type of granular cell tumours (GCTs) in the central nervous system.
  • We report a case of cerebral GCA in a 59-year-old man who suffered from diabetes and Addison-Biermer disease.

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  • (PMID = 19169970.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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99. Türck J, Oberdörfer C, Vogel T, Mackenzie CR, Däubener W: Enhancement of antimicrobial effects by glucocorticoids. Med Microbiol Immunol; 2005 Jan;194(1-2):47-53
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  • Glucocorticoids are frequently used in inflammatory central nervous system diseases to reduce the inflammatory reaction and cerebral edema.
  • We found that hydrocortisone and dexamethasone enhance IFN-gamma-mediated IDO activity in both human astrocytoma cells and native human astrocytes.

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  • (PMID = 14624357.001).
  • [ISSN] 0300-8584
  • [Journal-full-title] Medical microbiology and immunology
  • [ISO-abbreviation] Med. Microbiol. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Antiprotozoal Agents; 0 / Glucocorticoids; 0 / Indoleamine-Pyrrole 2,3,-Dioxygenase; 7S5I7G3JQL / Dexamethasone; 82115-62-6 / Interferon-gamma; EC 1.13.11.11 / Tryptophan Oxygenase; WI4X0X7BPJ / Hydrocortisone
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100. Kim MJ, Kim HS, Kim JH, Cho KG, Kim SY: Diagnostic accuracy and interobserver variability of pulsed arterial spin labeling for glioma grading. Acta Radiol; 2008 May;49(4):450-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIAL AND METHODS: Fifty-eight patients with 61 cerebral astrocytomas underwent conventional MR imaging and PASL.
  • There was a statistically significant difference in the rTPS between low- and high-grade astrocytomas (1.14 vs. 1.47, P<0.05).

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  • (PMID = 18415790.001).
  • [ISSN] 1600-0455
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Spin Labels
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