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1. Yeaney GA, O'Connor SM, Jankowitz BT, Hamilton RL: A 16-year-old male with a cerebellar mass. Brain Pathol; 2009 Jan;19(1):167-70
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  • [Title] A 16-year-old male with a cerebellar mass.
  • MRI revealed a cystic and solid, enhancing midline cerebellar lesion.
  • An infiltrating component resembling diffuse astrocytoma could be found in areas.
  • The pathologic diagnosis was pleomorphic xanthoastrocytoma (PXA) of the cerebellum.
  • This case is one of sixteen cerebellar PXAs reported in the literature.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis

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  • (PMID = 19076785.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Reticulin; 0 / Vimentin
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2. Neves AM, Thompson G, Carvalheira J, Trindade JC, Rueff J, Caetano JM, Casey JW, Hermouet S: Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma. Brain Res; 2008 Jul 24;1221:108-14
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  • [Title] Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma.
  • We investigated the hypothetical role of human herpesviruses (HHVs) in tumour formation of the cerebellum.
  • Thirty-five samples of pilocytic astrocytoma and 10 control samples of cerebellum from patients who died of unrelated diseases were examined.
  • In summary, EBV was the most frequent HHV detected in pilocytic astrocytoma, but at very low levels.
  • According to the actually accepted threshold the results suggest that EBV cannot be considered responsible for tumorigenesis of pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / virology. Cerebellar Neoplasms / virology. DNA, Viral / genetics. Herpesviridae / genetics. Herpesviridae Infections / complications. Herpesviridae Infections / genetics

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  • (PMID = 18565499.001).
  • [ISSN] 0006-8993
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA, Viral; EC 2.7.7.- / DNA Polymerase III; EC 2.7.7.- / DNA polymerase A
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3. Cuellar-Baena S, Morales JM, Martinetto H, Calvar J, Sevlever G, Castellano G, Cerdá-Nicolás M, Celda B, Monleon D: Comparative metabolic profiling of paediatric ependymoma, medulloblastoma and pilocytic astrocytoma. Int J Mol Med; 2010 Dec;26(6):941-8
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  • [Title] Comparative metabolic profiling of paediatric ependymoma, medulloblastoma and pilocytic astrocytoma.
  • The most common paediatric brain tumours include ependymomas, cerebellar astrocytomas and medulloblastomas.
  • Tumour types include ependymoma, medulloblastoma and pilocytic astrocytoma.


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4. Jea A, Coscarella E, Chintagumpala M, Bhattacharjee M, Whitehead WE, Curry DJ, Luerssen TG: Medulloblastoma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors in a child: case report. J Neurosurg Pediatr; 2010 Feb;5(2):149-54
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  • [Title] Medulloblastoma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors in a child: case report.
  • Brain MR imaging demonstrated a heterogeneously enhancing mixed solid/cystic mass of the left cerebellar hemisphere and a larger, midline, more homogeneously enhancing lesion of the superior vermis.
  • Pathological examination revealed the left cerebellar and superior vermian lesions to be a juvenile pilocytic astrocytoma and a medulloblastoma, respectively.
  • To the best of the authors' knowledge, they describe the first known pediatric case in which a medulloblastoma and a juvenile pilocytic astrocytoma presented as synchronous primary brain tumors.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebellar Neoplasms / pathology. Medulloblastoma / pathology


5. Vaquero E, Gómez CM, Quintero EA, González-Rosa JJ, Márquez J: Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor. Behav Brain Funct; 2008;4:18
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  • [Title] Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor.
  • BACKGROUND: This study was realized thanks to the collaboration of children and adolescents who had been resected from cerebellar tumors.
  • The astrocytoma group (CE, n = 13) did not receive additional treatments.
  • The Astrocytoma group also showed executive deficits in digits span, semantic fluency (animal category) and moderate to slight deficit in Stroop (word and colour) tests.
  • In the astrocytoma group, the tumor's localization and dentate affectation showed different profile and level of impairment: moderate to slight for vermal and hemispheric patients respectively.
  • CONCLUSION: Results suggest a differential prefrontal-like deficit due to cerebellar lesions and/or cerebellar-frontal diaschisis, as indicate the results in astrocytoma group (without treatments), that also can be generated and/or increased by treatments in the medulloblastoma group.
  • The results are also discussed in the context of the Cerebellar Cognitive Affective Syndrome.

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  • (PMID = 18412947.001).
  • [ISSN] 1744-9081
  • [Journal-full-title] Behavioral and brain functions : BBF
  • [ISO-abbreviation] Behav Brain Funct
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2362115
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6. Jacob K, Albrecht S, Sollier C, Faury D, Sader E, Montpetit A, Serre D, Hauser P, Garami M, Bognar L, Hanzely Z, Montes JL, Atkinson J, Farmer JP, Bouffet E, Hawkins C, Tabori U, Jabado N: Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours. Br J Cancer; 2009 Aug 18;101(4):722-33
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  • [Title] Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours.
  • We also establish that it is site specific as it occurs in the majority of cerebellar JPA (24 of 30 - 80%) followed by brainstem, hypothalamic/optic pathway JPA (10 of 16 - 62.5%) and is rare in hemispheric JPA (1 of 7 - 14%).
  • [MeSH-major] Astrocytoma / genetics. Biomarkers, Tumor / genetics. Brain Neoplasms / genetics. Chromosomes, Human, Pair 7 / genetics

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  • (PMID = 19603027.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carrier Proteins; EC 2.7.1.- / HIPK2 protein, human; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf; EC 2.7.11.24 / Mitogen-Activated Protein Kinases
  • [Other-IDs] NLM/ PMC2736806
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7. Castillo M: Stem cells, radial glial cells, and a unified origin of brain tumors. AJNR Am J Neuroradiol; 2010 Mar;31(3):389-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / etiology. Brain Neoplasms / etiology. Medulloblastoma / etiology. Neuroglia / pathology. Stem Cells / pathology
  • [MeSH-minor] Cerebellar Neoplasms / etiology. Cerebellar Neoplasms / pathology. Ependymoma / etiology. Ependymoma / pathology. Humans

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  • (PMID = 19797796.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Editorial
  • [Publication-country] United States
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8. Gheri CF, Buccoliero AM, Pansini G, Castiglione F, Garbini F, Moncini D, Maccari C, Mennonna P, Pellicanò G, Ammannati F, Taddei GL: Lipoastrocytoma: Case report and review of the literature. Neuropathology; 2010 Oct;30(5):553-8
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  • We report the case of an astrocytoma involving the upper part of the cerebellar-pontine angle and the right portion of the clivus starting from the brainstem with a diffuse lipomatous component in a 39 year-old man.
  • MRI revealed a ponto-cerebellar lesion that showed irregular enhancement after contrast administration.
  • Histologically the tumor showed the classical histology of low-grade astrocytoma and a portion of the lesion was composed of lipid-laden cells.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Lipomatosis / pathology
  • [MeSH-minor] Adult. Brain Stem / pathology. Cerebellum / pathology. Humans. Male

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  • [Copyright] © 2010 Japanese Society of Neuropathology.
  • (PMID = 20113404.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Australia
  • [Keywords] NOTNLM ; lipid vacuole / lipoastrocytoma / lipomatous / low grade astrocytoma
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9. El-Bahy K: Telovelar approach to the fourth ventricle: operative findings and results in 16 cases. Acta Neurochir (Wien); 2005 Feb;147(2):137-42; discussion 142
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  • Subtotal removal was achieved in the remaining patients (31.25%); three ependymomas, one medulloblastoma, and one anaplastic astrocytoma.
  • Cerebellar mutism was not observed in any patient and there was no mortality.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellum / pathology. Cerebellum / surgery. Fourth Ventricle / pathology. Fourth Ventricle / surgery. Neurosurgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / pathology. Astrocytoma / surgery. Cerebellar Ataxia / etiology. Cerebellar Ataxia / pathology. Cerebellar Ataxia / physiopathology. Child. Choroid Plexus / pathology. Choroid Plexus / surgery. Cranial Fossa, Posterior / surgery. Dermoid Cyst / pathology. Dermoid Cyst / surgery. Ependymoma / pathology. Ependymoma / surgery. Female. Humans. Magnetic Resonance Imaging. Male. Medulloblastoma / pathology. Medulloblastoma / surgery. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Papilloma, Choroid Plexus / pathology. Papilloma, Choroid Plexus / surgery. Postoperative Complications / etiology. Postoperative Complications / pathology. Postoperative Complications / physiopathology. Retrospective Studies. Treatment Outcome

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  • (PMID = 15605202.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Austria
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10. El Ayachi I, Baeza N, Fernandez C, Colin C, Scavarda D, Pesheva P, Figarella-Branger D: KIAA0510, the 3'-untranslated region of the tenascin-R gene, and tenascin-R are overexpressed in pilocytic astrocytomas. Neuropathol Appl Neurobiol; 2010 Aug;36(5):399-410
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  • [MeSH-major] Astrocytoma / genetics. Cerebellar Neoplasms / genetics. Gene Expression Regulation, Neoplastic. Tenascin / genetics

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  • (PMID = 20202125.001).
  • [ISSN] 1365-2990
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 3' Untranslated Regions; 0 / Tenascin; 147604-77-1 / tenascin R
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11. Happle C, Wetzke M, Hermann EJ, Krauss JK, Hartmann H, Lücke T: ['Cases against KiSS': a diagnostic algorithm for children with torticollis]. Klin Padiatr; 2009 Dec;221(7):430-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Algorithms. Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Cervical Vertebrae. Ganglioglioma / diagnosis. Magnetic Resonance Imaging. Neoplasms, Second Primary / diagnosis. Spinal Diseases / diagnosis. Torticollis / etiology

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  • [Copyright] (c) Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 20013566.001).
  • [ISSN] 1439-3824
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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12. Udayakumaran S, Ben Sira L, Constantini S: Chronic uncal herniation secondary to posterior fossa shunting: case report and literature review. Childs Nerv Syst; 2010 Feb;26(2):267-71
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  • CASE REPORT: A 15-year-old girl had a resection of a cerebellar pilocytic astrocytoma at 5 years of age.
  • Comparing the case reports in the literature with our case, we postulate that chronic uncal herniation is a complication of shunting of a posterior fossa fluid cavity in children, many of them with Dandy-Walker syndrome and/or other cerebellar cystic formations.
  • [MeSH-minor] Adolescent. Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Chronic Disease. Female. Humans. Intracranial Pressure. Magnetic Resonance Imaging. Temporal Lobe / diagnostic imaging. Temporal Lobe / pathology. Temporal Lobe / surgery. Tomography, X-Ray Computed

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  • (PMID = 19915852.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 15
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13. Kim SH, Kim TS: Squash smear findings of eosinophilic granular bodies in pilocytic astrocytoma. Acta Cytol; 2005 Jan-Feb;49(1):112-4
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  • [Title] Squash smear findings of eosinophilic granular bodies in pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Cytoplasmic Granules / pathology. Eosinophils / pathology. Specimen Handling / methods

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  • (PMID = 15717769.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Letter
  • [Publication-country] United States
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14. Rett D: Gaze-evoked nystagmus: a case report and literature review. Optometry; 2007 Sep;78(9):460-4
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  • Magnetic resonance imaging found a large, brainstem astrocytoma in the cerebellar-pontine angle.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Brain Stem. Fixation, Ocular. Nystagmus, Pathologic / etiology

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  • (PMID = 17765857.001).
  • [ISSN] 1529-1839
  • [Journal-full-title] Optometry (St. Louis, Mo.)
  • [ISO-abbreviation] Optometry
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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15. Li JY, Wang H, May S, Song X, Fueyo J, Fuller GN, Wang H: Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas. J Neurooncol; 2008 May;88(1):11-7
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  • [Title] Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas.
  • The c-Jun NH2-terminal kinase (JNK), which belongs to mitogen-activated protein kinase family, plays a major role in apoptosis in various cell types.
  • pJNK expression was not detected in the astrocytes or oligodendrocytes of any of 10 normal cerebral and cerebellar brain tissue samples.
  • [MeSH-minor] Astrocytoma / drug therapy. Astrocytoma / pathology. Blotting, Western. Cells, Cultured. Enzyme Activation / physiology. Glioblastoma / drug therapy. Glioblastoma / pathology. Gliosarcoma / drug therapy. Gliosarcoma / pathology. Humans. Immunohistochemistry. Oligodendroglioma / drug therapy. Oligodendroglioma / pathology


16. Stüer C, Vilz B, Majores M, Becker A, Schramm J, Simon M: Frequent recurrence and progression in pilocytic astrocytoma in adults. Cancer; 2007 Dec 15;110(12):2799-808
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frequent recurrence and progression in pilocytic astrocytoma in adults.
  • BACKGROUND: Most pilocytic astrocytomas (piloA) are benign growths (World Health Organization [WHO] grade 1) of the deep midline structures, the brainstem, and the cerebellum.
  • RESULTS: There were 20 patients (45%) with supratentorial lobar piloA (including 10 temporal/temporomesial tumors, 5 parietal tumors, 3 insular tumors, 1 frontal tumor, and 1 occipital tumors), 12 patients with cerebellar piloA, 7 patients with brainstem piloA, 2 patients with opticochiasmatic PiloA, 1 patient with intramedullary piloA, and 2 patients with piloA of the basal ganglia.
  • [MeSH-major] Astrocytoma / pathology. Astrocytoma / radiography. Brain Neoplasms / pathology

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  • [CommentIn] Nat Clin Pract Neurol. 2008 Jun;4(6):296-7 [18414467.001]
  • (PMID = 17973253.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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17. Bonner MJ, Hardy KK, Willard VW, Anthony KK, Hood M, Gururangan S: Social functioning and facial expression recognition in survivors of pediatric brain tumors. J Pediatr Psychol; 2008 Nov-Dec;33(10):1142-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Arthritis, Juvenile / psychology. Astrocytoma / psychology. Cerebellar Neoplasms / psychology. Child. Ependymoma / psychology. Female. Humans. Intelligence. Male. Medulloblastoma / psychology. Personal Construct Theory. Social Behavior Disorders / diagnosis. Social Behavior Disorders / psychology

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  • (PMID = 18390896.001).
  • [ISSN] 1465-735X
  • [Journal-full-title] Journal of pediatric psychology
  • [ISO-abbreviation] J Pediatr Psychol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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18. Deshmukh H, Yeh TH, Yu J, Sharma MK, Perry A, Leonard JR, Watson MA, Gutmann DH, Nagarajan R: High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas. Oncogene; 2008 Aug 7;27(34):4745-51
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  • [MeSH-major] Astrocytoma / genetics. Carrier Proteins / genetics. Cerebellar Neoplasms / genetics. Gene Amplification. Gene Expression Profiling / methods. Oligonucleotide Array Sequence Analysis / methods. Protein-Serine-Threonine Kinases / genetics

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  • (PMID = 18408760.001).
  • [ISSN] 1476-5594
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Carrier Proteins; EC 2.7.1.- / HIPK2 protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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19. Zuzak TJ, Poretti A, Drexel B, Zehnder D, Boltshauser E, Grotzer MA: Outcome of children with low-grade cerebellar astrocytoma: long-term complications and quality of life. Childs Nerv Syst; 2008 Dec;24(12):1447-55
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  • [Title] Outcome of children with low-grade cerebellar astrocytoma: long-term complications and quality of life.
  • OBJECTS: To study the long-term outcome of surgically treated low-grade cerebellar astrocytomas in children.
  • CONCLUSION: Childhood low-grade cerebellar astrocytomas have an excellent cure rate by tumor surgery alone.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Quality of Life

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  • (PMID = 18690461.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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20. Comincini S, Chiarelli LR, Zelini P, Del Vecchio I, Azzalin A, Arias A, Ferrara V, Rognoni P, Dipoto A, Nano R, Valentini G, Ferretti L: Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells. Oncol Rep; 2006 Dec;16(6):1325-32
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  • Besides, Dpl overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons.
  • In this study the doppel gene (PRND) mRNA and protein expression in PRT-HU2 and IPDDC-A2 astrocytoma-derived cell lines was investigated.
  • Northern blot analysis revealed two equally abundant PRND mRNA isoforms, while real-time PCR, on nuclear and cytoplasmic RNA fractions, and cRNA in situ hybridization, on astrocytoma cells and bioptical specimens, showed a nuclear retention of PRND transcripts.
  • [MeSH-major] Astrocytoma / metabolism. Brain Neoplasms / metabolism. Cell Nucleus / metabolism. Prions / biosynthesis. RNA, Messenger / metabolism

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  • (PMID = 17089057.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / PRND protein, human; 0 / Prions; 0 / RNA, Messenger
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21. Rueckriegel SM, Driever PH, Blankenburg F, Lüdemann L, Henze G, Bruhn H: Differences in supratentorial damage of white matter in pediatric survivors of posterior fossa tumors with and without adjuvant treatment as detected by magnetic resonance diffusion tensor imaging. Int J Radiat Oncol Biol Phys; 2010 Mar 1;76(3):859-66
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  • PATIENTS AND METHODS: Seventeen medulloblastoma (MB) patients who had received surgery and adjuvant treatment, 13 pilocytic astrocytoma (PA) patients who had been treated only with surgery, and age-matched healthy control subjects underwent magnetic resonance imaging on a 3-Tesla system.
  • RESULTS: Compared with control subjects, FA values of MB patients were significantly decreased in the cerebellar midline structures, in the frontal lobes, and in the callosal body.
  • Fractional anisotropy values of the PA patients were not only decreased in cerebellar hemispheric structures as expected, but also in supratentorial parts of the brain, with a distribution similar to that in MB patients.
  • CONCLUSIONS: Neurotoxic mechanisms that are present in PA patients (e.g., internal hydrocephalus and damaged cerebellar structures affecting neuronal circuits) contribute significantly to the alteration of supratentorial white matter in pediatric posterior fossa tumor patients.
  • [MeSH-major] Astrocytoma. Brain / pathology. Diffusion Magnetic Resonance Imaging / methods. Infratentorial Neoplasms. Medulloblastoma. Survivors
  • [MeSH-minor] Adolescent. Anisotropy. Axons. Case-Control Studies. Cerebellum / drug effects. Cerebellum / pathology. Cerebellum / radiation effects. Chemotherapy, Adjuvant / adverse effects. Child. Child, Preschool. Cranial Irradiation / adverse effects. Female. Humans. Leukoencephalopathies / etiology. Leukoencephalopathies / pathology. Male. Radiotherapy, Adjuvant / adverse effects

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  • [Copyright] Copyright (c) 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19540067.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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22. Rafique MZ, Ahmad MN, Yaqoob N, Ahsan H: Diffuse bilateral thalamic astrocytoma. J Coll Physicians Surg Pak; 2007 Mar;17(3):170-2
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  • [Title] Diffuse bilateral thalamic astrocytoma.
  • Diffuse astrocytoma with bilateral thalamic involvement is extremely rare.
  • Biopsy showed grade III Astrocytoma with bilateral thalamic involvement.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Thalamic Diseases / pathology

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  • (PMID = 17374306.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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23. Okamoto H, Mineta T, Ueda S, Nakahara Y, Shiraishi T, Tamiya T, Tabuchi K: Detection of JC virus DNA sequences in brain tumors in pediatric patients. J Neurosurg; 2005 Apr;102(3 Suppl):294-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Antigens, Viral, Tumor / genetics. Astrocytoma / pathology. Astrocytoma / virology. Base Sequence. Blotting, Southern. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / virology. Cerebral Ventricle Neoplasms / pathology. Cerebral Ventricle Neoplasms / virology. Child. Child, Preschool. Ependymoma / pathology. Ependymoma / virology. Female. Humans. Infant. Male. Medulloblastoma / pathology. Medulloblastoma / virology. Papilloma, Choroid Plexus / pathology. Papilloma, Choroid Plexus / virology. Polymerase Chain Reaction. Supratentorial Neoplasms / pathology. Supratentorial Neoplasms / virology

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  • (PMID = 15881753.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Viral, Tumor; 0 / DNA, Viral
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24. Ramírez-Zamora A, Biller J: Brainstem cavernous malformations: a review with two case reports. Arq Neuropsiquiatr; 2009 Sep;67(3B):917-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Pregnancy. Radiotherapy / adverse effects

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  • (PMID = 19838533.001).
  • [ISSN] 1678-4227
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 40
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25. Battaglia F, Uro-Coste E, Delisle MB, Tannier C: [Radiation-induced cavernoma: two cases]. Rev Neurol (Paris); 2008 May;164(5):468-71
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  • The first case was a 55-year-old man given radiation and chemotherapy for frontal astrocytoma at the age of 46.
  • [MeSH-minor] Adult. Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Cerebral Hemorrhage / pathology. Cerebral Ventricles / pathology. Female. Histocytochemistry. Humans. Magnetic Resonance Imaging. Male. Medulloblastoma / radiotherapy. Middle Aged. Pons / pathology

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  • (PMID = 18555880.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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26. Dunn IF, Agarwalla PK, Papanastassiou AM, Butler WE, Smith ER: Multiple pilocytic astrocytomas of the cerebellum in a 17-year-old patient with neurofibromatosis type I. Childs Nerv Syst; 2007 Oct;23(10):1191-4
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  • [Title] Multiple pilocytic astrocytomas of the cerebellum in a 17-year-old patient with neurofibromatosis type I.
  • The most common of these are hypothalamic-optic gliomas, followed by brainstem and cerebellar pilocytic astrocytomas.
  • The most frequent combination in NFI patients with more than one pilocytic astrocytoma is optic tract/hypothalamic and brainstem.
  • This report presents the first documented case, to our knowledge, of multiple pilocytic astrocytomas in the cerebellum of a patient with NF1.
  • CONCLUSION: The finding of multiple cerebellar pilocytic astrocytomas in a patient with NF1 is important because it expands the spectrum of presentations for patients with NF1 and also highlights specific diagnostic and therapeutic challenges faced by the treating physicians.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Neurofibromatosis 1 / pathology

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  • (PMID = 17457593.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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27. Battaglia S, Albini Riccioli L, Zucchelli M, Leonardi M: 3 Tesla MR Study of Cerebellar Medulloblastoma. Neuroradiol J; 2007 Jan 31;19(6):722-6
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  • [Title] 3 Tesla MR Study of Cerebellar Medulloblastoma.
  • Medulloblastoma belongs to the group of highly malignant neuroepithelial tumours and is the commonest tumour in childhood (average age nine years) followed by astrocytoma 1.
  • Medulloblastoma usually arises in the posterior fossa, namely the cerebellar vermis, and more seldom in the fourth ventricle, supratentorium and spinal cord.
  • We describe the 3 Tesla magnetic resonance (MR) features of a medulloblastoma located in the right cerebellar hemisphere adhering to the tentorium in a 16-year-old male.

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  • (PMID = 24351298.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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28. Toyoda T, Ochiai K, Hatai H, Murakami M, Ono E, Kimura T, Umemura T: Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma. Vet Pathol; 2006 May;43(3):294-301
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  • [Title] Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma.
  • Fowl glioma-inducing virus (FGV), which belongs to subgroup A of avian leukosis virus (ALV), shows tumorigenicity and pathogenicity, mainly in the nervous system, and causes astrocytoma and perineurioma.
  • Apart from these neoplasms, cerebellar anomaly was found in chickens infected with FGV in ovo.
  • The study reported here describes the morphologic characteristics of the affected cerebellum.
  • The cerebellar anomaly included diffuse depletion of granular cells of the internal granular layer (IGL), remnants of the external granular layer (EGL), and disorganization of the Purkinje cell layer.
  • These cerebellar changes were observed in all birds except one.
  • These results suggested that the cerebellar anomaly was hypoplasia, principally resulting from the apoptosis of granular cells in the EGL and ML caused by FGV infection and that the cell loss induced obstruction of granular cell migration and disarrangement of Bergmann's fibers in the ML.
  • [MeSH-major] Avian Leukosis Virus / pathogenicity. Cerebellar Diseases / veterinary. Cerebellum / pathology. Glioma / veterinary. Poultry Diseases / pathology. Poultry Diseases / virology

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  • (PMID = 16672576.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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29. Gunny RS, Hayward RD, Phipps KP, Harding BN, Saunders DE: Spontaneous regression of residual low-grade cerebellar pilocytic astrocytomas in children. Pediatr Radiol; 2005 Nov;35(11):1086-91
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  • [Title] Spontaneous regression of residual low-grade cerebellar pilocytic astrocytomas in children.
  • BACKGROUND: Cerebellar low-grade astrocytomas (CLGAs) of childhood are benign tumours and are usually curable by surgical resection alone or combined with adjuvant radiotherapy.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Magnetic Resonance Imaging / methods. Neoplasm Recurrence, Local / pathology. Neoplasm Regression, Spontaneous / pathology. Risk Assessment / methods

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  • (PMID = 16047140.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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30. Bassi R, Anelli V, Giussani P, Tettamanti G, Viani P, Riboni L: Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors. Glia; 2006 Apr 15;53(6):621-30
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  • [Title] Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors.
  • The mitogenic role of sphingosine-1-phosphate (S1P) and its involvement in basic fibroblast growth factor (bFGF)-induced proliferation were examined in primary cultures of cerebellar astrocytes.
  • These results support the view that S1P exerted a mitogenic effect on cerebellar astrocytes extracellularly, most likely through cell surface S1P receptors.
  • In agreement, mRNAs for S1P1, S1P2, and S1P3 receptors are expressed in cerebellar astrocytes (Anelli et al., 2005.
  • Cerebellum 1:129-135), efficiently inhibited S1P-induced proliferation.
  • [MeSH-major] Astrocytes / metabolism. Cell Proliferation / drug effects. Cerebellum / metabolism. Fibroblast Growth Factor 2 / pharmacology. GTP-Binding Protein alpha Subunits, Gi-Go / metabolism. Lysophospholipids / metabolism. Receptors, Lysosphingolipid / metabolism. Sphingosine / analogs & derivatives
  • [MeSH-minor] Animals. Animals, Newborn. Astrocytoma / metabolism. Astrocytoma / physiopathology. Brain Neoplasms / metabolism. Brain Neoplasms / physiopathology. Cell Transformation, Neoplastic / metabolism. Cells, Cultured. Ceramides / metabolism. Ceramides / pharmacology. DNA Replication / drug effects. DNA Replication / physiology. Enzyme Inhibitors / pharmacology. Extracellular Fluid / drug effects. Extracellular Fluid / metabolism. Extracellular Signal-Regulated MAP Kinases / drug effects. Extracellular Signal-Regulated MAP Kinases / metabolism. Gliosis / metabolism. Gliosis / physiopathology. Mitosis / drug effects. Mitosis / physiology. Phosphotransferases (Alcohol Group Acceptor) / antagonists & inhibitors. Phosphotransferases (Alcohol Group Acceptor) / metabolism. Rats. Signal Transduction / drug effects. Signal Transduction / physiology

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  • (PMID = 16470810.001).
  • [ISSN] 0894-1491
  • [Journal-full-title] Glia
  • [ISO-abbreviation] Glia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ceramides; 0 / Enzyme Inhibitors; 0 / Lysophospholipids; 0 / Receptors, Lysosphingolipid; 103107-01-3 / Fibroblast Growth Factor 2; 26993-30-6 / sphingosine 1-phosphate; EC 2.7.1.- / Phosphotransferases (Alcohol Group Acceptor); EC 2.7.1.- / sphingosine kinase; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 3.6.5.1 / GTP-Binding Protein alpha Subunits, Gi-Go; NGZ37HRE42 / Sphingosine
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31. Hope AJ, Mansur DB, Tu PH, Simpson JR: Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma. Childs Nerv Syst; 2006 Sep;22(9):1201-7
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  • [Title] Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma.
  • DISCUSSION: In this study, we report the case of a 15-year-old boy treated for medulloblastoma with surgery and craniospinal radiotherapy, who developed a meningioma 18 years after initial treatment and subsequently an anaplastic astrocytoma 23 years after primary treatment.
  • The patient is currently alive but with recurrent astrocytoma after a complete remission on temozolomide monotherapy.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / radiotherapy. Cranial Irradiation / adverse effects. Medulloblastoma / radiotherapy. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Neoplasms, Radiation-Induced / diagnosis. Neoplasms, Second Primary / diagnosis

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  • (PMID = 16570196.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 40
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32. Taraszewska A, Czernicki Z, Andrychowski J: Hemosiderin pigmentation of tumour cells in cerebellar pilocytic astrocytoma associated with post-traumatic hemorrhage in adults. Folia Neuropathol; 2005;43(3):172-7
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  • [Title] Hemosiderin pigmentation of tumour cells in cerebellar pilocytic astrocytoma associated with post-traumatic hemorrhage in adults.
  • The pilocytic astrocytoma is only rarely associated with gross intratumoral hemorrhage despite rich vasculature and blood vessel changes, accompanied often by perivascular depots of hemosiderin.
  • We report an unusual case of pigmented cerebellar pilocytic astrocytoma presenting with posttraumatic hemorrhage in a 38-year-old man with no history related to the tumor.
  • CT and MRI examination after head injury demonstrated unexpectedly the cystic lesion of 2 cm in diameter in the region of the right cerebellar hemisphere and vermis.
  • Histopathological examination revealed pilocytic astrocytoma tissue with broad hemorrhagic changes and with an unusual pattern of massive pigmentation of the cytoplasm of pilocytic astrocytes, consistent with hemosiderosis.
  • To our knowledge, this is the first reported case of pigmented pilocytic astrocytoma exhibiting extensive intracellular hemosiderin deposition.

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  • (PMID = 16245213.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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33. Masri A, Bakri FG, Assaf A, Musharbash A, Haroun AA, Zak I: Intra-axial dermoid tumor mimicking pilocytic astrocytoma. Childs Nerv Syst; 2009 Apr;25(4):395-6
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  • [Title] Intra-axial dermoid tumor mimicking pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Dermoid Cyst / pathology

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  • [CommentOn] Childs Nerv Syst. 2008 Jan;24(1):157-9 [17657495.001]
  • [Cites] Childs Nerv Syst. 2008 Jan;24(1):157-9 [17657495.001]
  • (PMID = 19184043.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Germany
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34. Johnson AH, Jordan C, Mazewski CM: Off-therapy headaches in pediatric brain tumor patients: a retrospective review. J Pediatr Oncol Nurs; 2009 Nov-Dec;26(6):354-61
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  • In all, 81 charts were reviewed from which headaches in 3 subtypes of tumors were identified (29 medulloblastomas, 36 cerebellar juvenile pilocytic astrocytomas [JPAs], and 16 craniopharyngiomas).
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Craniopharyngioma / complications. Headache / etiology. Medulloblastoma / complications. Pituitary Neoplasms / complications

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  • (PMID = 19687465.001).
  • [ISSN] 1532-8457
  • [Journal-full-title] Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses
  • [ISO-abbreviation] J Pediatr Oncol Nurs
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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35. Daglioglu E, Ergungor F, Hatipoglu HG, Okay O, Dalgic A, Orhan G, Unal T: Cerebral leukoencephalopathy with calcifications and cysts operated for signs of increased intracranial pressure: case report. Surg Neurol; 2009 Aug;72(2):177-81
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  • It should be differentiated from FD or bilateral striopallidodentate calcinosis and astrocytoma.
  • CASE DESCRIPTION: We report a sporadic case operated for signs of increased ICP and cerebellar cystic mass.
  • The patient had symmetric bilateral cerebral and cerebellar calcifications, white matter edema, and a secondary thalamic cyst as well.
  • After resection of the cerebellar mass, clinical picture returned to normal and edematous findings on MRI resolved in addition to a decrease in size of the thalamic lesion on follow-up.
  • [MeSH-major] Calcinosis / diagnosis. Central Nervous System Cysts / diagnosis. Cerebellar Diseases / complications. Cerebellar Diseases / diagnosis. Cerebellum / pathology. Intracranial Hypertension / etiology. Intracranial Hypertension / surgery

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  • (PMID = 18514290.001).
  • [ISSN] 1879-3339
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Rønning C, Sundet K, Due-Tønnessen B, Lundar T, Helseth E: Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood. Pediatr Neurosurg; 2005 Jan-Feb;41(1):15-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood.
  • Traditionally, the cerebral hemispheres have been regarded as the region of the brain responsible for cognitive functions, while the cerebellum has been considered to be primarily involved in motor functions.
  • Recent studies focus also on the possible involvement of the cerebellum in neurocognitive functions.
  • The aim of this study was to determine the neuropsychological profile of young adults treated for a posterior fossa tumor in childhood and look for possible support for the presence of the so-called 'cerebellar cognitive affective syndrome' in these patients.
  • The astrocytoma group (n = 12) had been treated for a low-grade cerebellar astrocytoma with surgery alone (mean age at surgery was 8.6 years and mean age at neuropsychological testing was 23.5 years).
  • Nonetheless, the astrocytoma group also had impaired scores compared with standard norms on measures of motor speed, attention and executive function.
  • No significant correlation between age at time of treatment and grade of neuropsychological impairment was found in the astrocytoma group, though there was a tendency that young age at time of treatment correlated with better outcome on IQ measures.
  • CONCLUSIONS: Persistent cognitive dysfunction was detected in patients treated for posterior fossa medulloblastoma and cerebellar astrocytoma.
  • The astrocytoma group was treated with surgery alone, indicating that a cerebellar lesion can result in cognitive dysfunction.
  • Thus, this study gives support to the existence of the cerebellar cognitive affective syndrome.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Cerebellum / physiopathology. Cerebellum / surgery. Cognition Disorders / etiology. Medulloblastoma / surgery

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 15886508.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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37. Turgut M: Transient cerebellar mutism in childhood. Childs Nerv Syst; 2007 May;23(5):477
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transient cerebellar mutism in childhood.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Medulloblastoma / surgery. Mutism / etiology. Postoperative Complications / psychology

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  • [CommentOn] Childs Nerv Syst. 2006 Feb;22(2):132-8 [16155765.001]
  • [Cites] Br J Neurosurg. 2001 Feb;15(1):47-50 [11303661.001]
  • [Cites] Childs Nerv Syst. 2006 Feb;22(2):132-8 [16155765.001]
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  • (PMID = 17384951.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Germany
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38. Trivedi A, Hiran S: Calcified epidural hematoma in pediatric age group: A report of two cases. J Neurosci Rural Pract; 2010 Jul;1(2):89-91
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  • The authors present a rare case of calcified (ossified) chronic epidural hematoma developed in a six-and-a-half-year-old female patient who was operated for cerebellar astrocytoma 6 months earlier.

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  • (PMID = 21808510.001).
  • [ISSN] 0976-3155
  • [Journal-full-title] Journal of neurosciences in rural practice
  • [ISO-abbreviation] J Neurosci Rural Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3139356
  • [Keywords] NOTNLM ; Epidural hematoma / calcified / pediatric epidural hematoma
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39. Baron PW, Majlessipour F, Bedros AA, Zuppan CW, Ben-Youssef R, Yanni G, Ojogho ON, Concepcion W: Undifferentiated embryonal sarcoma of the liver successfully treated with chemotherapy and liver resection. J Gastrointest Surg; 2007 Jan;11(1):73-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The first patient also had a concurrent cerebellar tumor (pilocytic astrocytoma), for which he first underwent craniotomy and resection, delaying the liver tumor resection by 10 weeks.

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  • (PMID = 17390190.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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40. Richter S, Schoch B, Kaiser O, Groetschel H, Dimitrova A, Hein-Kropp C, Maschke M, Gizewski ER, Timmann D: Behavioral and affective changes in children and adolescents with chronic cerebellar lesions. Neurosci Lett; 2005 Jun 10-17;381(1-2):102-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Behavioral and affective changes in children and adolescents with chronic cerebellar lesions.
  • The aim of the present study was to investigate if clinically relevant affective or behavioral changes as described in adults in the cerebellar affective syndrome by Schmahmann and Sherman [The cerebellar cognitive affective syndrome, Brain 121 (1998) 561-579] are likely to occur as a long-term sequelae of cerebellar vermis lesions in children.
  • Affect and behavior were assessed in children after cerebellar tumor surgery by means of experimenter ratings based on the description of the cerebellar affective syndrome and free ratings by the patients and their parents.
  • Twelve children and adolescents with a former cerebellar astrocytoma surgery without subsequent radiation or chemotherapy participated.
  • [MeSH-major] Cerebellar Diseases / complications. Cerebellar Diseases / diagnosis. Mental Disorders / diagnosis. Mental Disorders / etiology. Mood Disorders / diagnosis. Mood Disorders / etiology


41. Hashiguchi K, Morioka T, Samura K, Miyagi Y, Yoshida F, Nagata S, Sasaki T: Medial temporal lobe epilepsy associated with misplacement of a ventricular shunting catheter. J Clin Neurosci; 2008 Aug;15(8):939-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • At 8 years of age, the patient had undergone total removal of a cerebellar astrocytoma and placement of a Torkildsen's ventriculo-cisternal shunt for obstructive hydrocephalus.

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  • (PMID = 18502644.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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42. Beebe DW, Ris MD, Armstrong FD, Fontanesi J, Mulhern R, Holmes E, Wisoff JH: Cognitive and adaptive outcome in low-grade pediatric cerebellar astrocytomas: evidence of diminished cognitive and adaptive functioning in National Collaborative Research Studies (CCG 9891/POG 9130). J Clin Oncol; 2005 Aug 1;23(22):5198-204
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cognitive and adaptive outcome in low-grade pediatric cerebellar astrocytomas: evidence of diminished cognitive and adaptive functioning in National Collaborative Research Studies (CCG 9891/POG 9130).
  • However, small case series have called that assumption into question, and have also suggested that nonirradiated cerebellar tumors can cause location-specific cognitive and adaptive impairment.
  • This study (1) assessed whether resected but not irradiated pediatric cerebellar tumors are associated with cognitive and adaptive functioning deficits, and (2) examined the effect of tumor location and medical complications on cognitive and adaptive functioning.
  • PATIENTS AND METHODS: The sample was composed of 103 children aged 3 to 18 years with low-grade cerebellar astrocytomas, who underwent only surgical treatment as part of Children's Cancer Group protocol 9891 or Pediatric Oncology Group protocol 9130.
  • Within this group of children with cerebellar tumors, tumor location had little effect on cognitive, adaptive, or medical outcome.
  • However, the elevated risk of deficits in this population runs contrary to clinical lore, and suggests that clinicians should attend to the functional outcomes of children who undergo only surgical treatment for cerebellar tumors.
  • [MeSH-major] Astrocytoma / complications. Astrocytoma / psychology. Cerebellar Neoplasms / complications. Cerebellar Neoplasms / psychology. Cognition Disorders / etiology

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  • (PMID = 16051961.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Saunders DE, Phipps KP, Wade AM, Hayward RD: Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma. J Neurosurg; 2005 Mar;102(2 Suppl):172-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma.
  • OBJECT: The authors sought to evaluate surveillance strategies for the detection and monitoring of residual and recurrent disease in children with cerebellar low-grade astrocytomas (CLGAs) treated surgically or with radiotherapy.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Magnetic Resonance Imaging. Neoplasm, Residual / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Cerebellum / pathology. Cerebellum / radiography. Cerebellum / surgery. Child. Child, Preschool. Disease Progression. Female. Follow-Up Studies. Humans. Infant. Male. Neoplasm Recurrence, Local / epidemiology. Neoplasm Staging. Postoperative Care. Remission, Spontaneous. Time Factors


44. Spetzler RF: Subtemporal transtentorial approach. J Neurosurg; 2006 May;104(5):854; author reply 855-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Hemangioblastoma / surgery. Infratentorial Neoplasms / surgery. Temporal Lobe / surgery
  • [MeSH-minor] Cerebellum / surgery. Humans. Treatment Outcome

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  • [CommentOn] J Neurosurg. 2005 Nov;103(5):783-8 [16304980.001]
  • (PMID = 16703898.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Comment; Comparative Study; Letter
  • [Publication-country] United States
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45. Lee CS, Huh JS, Sim KB, Kim YW: Cerebellar pilocytic astrocytoma presenting with intratumor bleeding, subarachnoid hemorrhage, and subdural hematoma. Childs Nerv Syst; 2009 Jan;25(1):125-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar pilocytic astrocytoma presenting with intratumor bleeding, subarachnoid hemorrhage, and subdural hematoma.
  • INTRODUCTION: Massive intracranial hemorrhage is a very rare initial presentation of cerebellar pilocytic astrocytomas.
  • There are no reports in the medical literature on a cerebellar pilocytic astrocytoma presenting with intratumor bleeding (ITB), subarachnoid hemorrhage (SAH), and subdural hematoma (SDH).
  • Magnetic resonance imaging showed a mass with ITB at the left cerebellar hemisphere in addition to SDH in the posterior fossa and SAH at the interpeduncular cistern.
  • On incising the dura, we found SDH, the tumor was visible at the cerebellar cortex, and near total removal followed.
  • Microscopic examination of tissue sections revealed a pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Hematoma, Subdural / etiology. Subarachnoid Hemorrhage / etiology

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  • (PMID = 18629510.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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46. Harris LM, Davies NP, Macpherson L, Lateef S, Natarajan K, Brundler MA, Sgouros S, English MW, Arvanitis TN, Grundy RG, Peet AC: Magnetic resonance spectroscopy in the assessment of pilocytic astrocytomas. Eur J Cancer; 2008 Nov;44(17):2640-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Prior to treatment, supratentorial tumours had significantly higher myo-inositol (p<0.01, t-test) and glutamate plus glutamine (p=0.02, t-test) than cerebellar tumours.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Magnetic Resonance Spectroscopy. Supratentorial Neoplasms / diagnosis

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  • (PMID = 18835152.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0601327; United Kingdom / Department of Health / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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47. Kawarabuki K, Ohta T, Hashimoto N, Wada K, Maruno M, Yamaki T, Ueda S: Cerebellar glioblastoma genetically defined as a secondary one. Clin Neuropathol; 2005 Mar-Apr;24(2):64-8
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  • [Title] Cerebellar glioblastoma genetically defined as a secondary one.
  • We report here the case of a 29-year-old woman with cerebellar glioblastma.
  • In the present case, tumor lesions were observed in each cerebellar hemisphere.
  • The left-side lesion was diagnosed as glioblastoma, and the right-side lesion as malignant astrocytoma by histopathology.
  • [MeSH-major] Cerebellar Neoplasms / genetics. Glioblastoma / genetics. Neoplasms, Second Primary / genetics


48. Huber JF, Bradley K, Spiegler BJ, Dennis M: Long-term effects of transient cerebellar mutism after cerebellar astrocytoma or medulloblastoma tumor resection in childhood. Childs Nerv Syst; 2006 Feb;22(2):132-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term effects of transient cerebellar mutism after cerebellar astrocytoma or medulloblastoma tumor resection in childhood.
  • BACKGROUND: Following cerebellar tumor resection, some patients develop transient cerebellar mutism (TCM).
  • Although the mutism resolves, it is not known whether there are long-term motor speech deficits in patients with TCM that are in excess of those in individuals with cerebellar tumors who had not developed postoperative TCM.
  • METHODS: Long-term survivors of cerebellar tumors resected in childhood who developed TCM were matched to survivors without TCM and to controls.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Medulloblastoma / surgery. Mutism / etiology. Postoperative Complications

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  • (PMID = 16155765.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P01 HD 35946
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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49. Hamlat A, Le Strat A, Guegan Y, Ben-Hassel M, Saikali S: Cerebellar pleomorphic xanthoastrocytoma: case report and literature review. Surg Neurol; 2007 Jul;68(1):89-94; discussion 94-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar pleomorphic xanthoastrocytoma: case report and literature review.
  • METHODS: The authors report a case of cerebellar PXA with rapid malignant transformation in a 58-year-old woman and review the rare presentations and atypical features of this tumor.
  • RESULTS: Among the "unusual" locations, the most frequent is the cerebellum with 15 cases having been described, 9 in adults, with an average age of 33 years.
  • CONCLUSIONS: The clinicopathologic features of cerebellar PXA show some differences from PXA located in the cerebral hemispheres.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 17537486.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
  • [Number-of-references] 28
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50. Capper D, Mittelbronn M, Goeppert B, Meyermann R, Schittenhelm J: Secreted protein, acidic and rich in cysteine (SPARC) expression in astrocytic tumour cells negatively correlates with proliferation, while vascular SPARC expression is associated with patient survival. Neuropathol Appl Neurobiol; 2010 Apr;36(3):183-97
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  • RESULTS: In normal brain, SPARC is expressed in cortical marginal glia, cerebellar Bergmann glia and focally in white matter but is absent in neurones or vessels.
  • [MeSH-major] Astrocytoma / metabolism. Blood Vessels / metabolism. Brain / metabolism. Brain Neoplasms / metabolism. Cell Proliferation. Osteonectin / metabolism

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  • (PMID = 20132490.001).
  • [ISSN] 1365-2990
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Osteonectin; 0 / RNA, Messenger
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51. Ramat S, Leigh RJ, Zee DS, Optican LM: Ocular oscillations generated by coupling of brainstem excitatory and inhibitory saccadic burst neurons. Exp Brain Res; 2005 Jan;160(1):89-106
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  • During combined saccade-vergence, normal subjects and the cerebellar patient developed small-amplitude (0.1 - 0.5 degrees), high-frequency (27-35 Hz), conjugate horizontal saccadic oscillations.
  • The feedback included the cerebellar fastigial nuclei.
  • The finding of saccadic oscillations in the cerebellar patient is compatible with the new model but not with the recent models including the fastigial nuclei in the classic negative-feedback loop model.
  • [MeSH-major] Astrocytoma / physiopathology. Biological Clocks / physiology. Brain Stem / physiology. Cerebellar Neoplasms / physiopathology. Cerebellar Nuclei / physiology. Neurons / physiology. Saccades / physiology

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  • (PMID = 15289966.001).
  • [ISSN] 0014-4819
  • [Journal-full-title] Experimental brain research
  • [ISO-abbreviation] Exp Brain Res
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY01849; United States / NEI NIH HHS / EY / EY06717
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Germany
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52. Debono B, Derrey S, Rabehenoina C, Proust F, Freger P, Laquerrière A: Primary diffuse multinodular leptomeningeal gliomatosis: case report and review of the literature. Surg Neurol; 2006 Mar;65(3):273-82; discussion 282
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  • Histological examination revealed an anaplastic astrocytoma.
  • RESULTS: Complete neuraxis postmortem examination revealed no intraparenchymatous glioma and was conclusive for the diagnosis of primary leptomeningeal gliomatosis (astrocytic, World Health Organization grade III), with a multinodular pattern in the spinal cord, the brainstem, and the brain base with diffuse extension into the cerebellar subarachnoid spaces.
  • [MeSH-major] Astrocytoma / surgery. Meningeal Neoplasms / surgery. Neoplasms, Neuroepithelial / surgery. Peripheral Nervous System Neoplasms / surgery. Spinal Nerve Roots / surgery
  • [MeSH-minor] Brain / pathology. Cerebellum / pathology. Diagnosis, Differential. Fatal Outcome. Humans. Intracranial Pressure / physiology. Male. Meninges / pathology. Middle Aged. Neoplasm Invasiveness / pathology. Neurologic Examination. Prognosis

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  • (PMID = 16488248.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 39
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53. Arai K, Sato N, Aoki J, Yagi A, Taketomi-Takahashi A, Morita H, Koyama Y, Oba H, Ishiuchi S, Saito N, Endo K: MR signal of the solid portion of pilocytic astrocytoma on T2-weighted images: is it useful for differentiation from medulloblastoma? Neuroradiology; 2006 Apr;48(4):233-7
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  • [Title] MR signal of the solid portion of pilocytic astrocytoma on T2-weighted images: is it useful for differentiation from medulloblastoma?
  • BACKGROUND AND PURPOSE: Although imaging features of cerebellar pilocytic astrocytoma and medulloblastoma have been described in many texts, original comparisons of magnetic resonance intensity between these two tumours are limited.
  • METHODS: MR images of ten cerebellar pilocytic astrocytomas and ten medulloblastomas were reviewed.
  • CONCLUSION: A signal intensity of the solid portion isointense to CSF on T2-weighted images was characteristic of cerebellar pilocytic astrocytomas; this was not observed in medulloblastomas.
  • Attention to T2-weighted imaging of the solid portions of a tumour is easy and helpful in differentiating between cerebellar pilocytic astrocytoma and medulloblastoma.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Magnetic Resonance Imaging / methods. Medulloblastoma / diagnosis

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  • (PMID = 16550430.001).
  • [ISSN] 0028-3940
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Journal Article
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54. Adachi J, Nishikawa R, Hirose T, Matsutani M: Mixed neuronal-glial tumor of the fourth ventricle and successful treatment of postoperative mutism with bromocriptine: case report. Surg Neurol; 2005 Apr;63(4):375-9
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  • We describe the clinicopathologic features of a very rare rosette-forming glioneuronal tumor of the fourth ventricle and propose bromocriptine as a useful therapeutic agent for cerebellar mutism after posterior fossa surgery.
  • Postoperatively, the patient manifested cerebellar mutism.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Bromocriptine / therapeutic use. Cerebral Ventricles / pathology. Dopamine Agonists / therapeutic use. Mutism / drug therapy. Mutism / etiology. Neurocytoma / surgery. Postoperative Complications / drug therapy

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  • (PMID = 15808729.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dopamine Agonists; 3A64E3G5ZO / Bromocriptine
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55. Attard TM, Giglio P, Koppula S, Snyder C, Lynch HT: Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis. Cancer; 2007 Feb 15;109(4):761-6
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  • They are at an increased risk of brain tumors, including cerebellar medulloblastoma, when compared with the general population (Brain Tumor Polyposis-BTP Type 2).
  • Other histologic subtypes included astrocytoma and ependymoma.


56. Daszkiewicz P, Maryniak A, Roszkowski M, Barszcz S: Long-term functional outcome of surgical treatment of juvenile pilocytic astrocytoma of the cerebellum in children. Childs Nerv Syst; 2009 Jul;25(7):855-60
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  • [Title] Long-term functional outcome of surgical treatment of juvenile pilocytic astrocytoma of the cerebellum in children.
  • PURPOSE: Increasing incidence of pediatric brain tumors and improving survival rates encouraged us to assess long-term functional outcome of patients with cerebellar juvenile pilocytic astrocytoma (JPA).
  • CONCLUSIONS: Long-term functional treatment outcome of cerebellar JPA is relatively favorable, in spite of permanent neurological deficits and emotional disorders in over half of the patients.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Cerebellum / surgery. Child. Child, Preschool. Education. Female. Follow-Up Studies. Humans. Infant. Male. Mood Disorders / etiology. Nervous System Diseases / etiology. Parents / psychology. Patient Satisfaction. Surveys and Questionnaires. Survival. Treatment Outcome. Young Adult

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  • (PMID = 19418058.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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57. Jalali R, Mallick I, Dutta D, Goswami S, Gupta T, Munshi A, Deshpande D, Sarin R: Factors influencing neurocognitive outcomes in young patients with benign and low-grade brain tumors treated with stereotactic conformal radiotherapy. Int J Radiat Oncol Biol Phys; 2010 Jul 15;77(4):974-9
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  • METHODS AND MATERIALS: Twenty-eight patients (median age, 13 years) with residual/progressive brain tumors (10 craniopharyngioma, 8 cerebellar astrocytoma, 6 optic pathway glioma and 4 cerebral low-grade glioma) were treated with SCRT to a dose of 54 Gy in 30 fractions over 6 weeks.
  • [MeSH-minor] Adolescent. Astrocytoma / radiotherapy. Cerebellar Neoplasms / psychology. Cerebellar Neoplasms / radiotherapy. Child. Cognition / radiation effects. Craniopharyngioma / psychology. Craniopharyngioma / radiotherapy. Female. Humans. Male. Optic Nerve Glioma / radiotherapy. Prospective Studies. Radiotherapy, Conformal / methods. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19864079.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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58. Richter S, Schoch B, Ozimek A, Gorissen B, Hein-Kropp C, Kaiser O, Hövel M, Wieland R, Gizewski E, Ziegler W, Timmann D: Incidence of dysarthria in children with cerebellar tumors: a prospective study. Brain Lang; 2005 Feb;92(2):153-67
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  • [Title] Incidence of dysarthria in children with cerebellar tumors: a prospective study.
  • The present study investigated dysarthric symptoms in children with cerebellar tumors.
  • Ten children with cerebellar tumors and 10 orthopedic control children were tested prior and one week after surgery.
  • Localization of the cerebellar lesions were defined after manual transfer from individual 2D-MR images onto 3D images of a spatially normalized healthy brain.
  • Cerebellar children showed few and mild clinical signs of dysarthria.
  • In five cerebellar children, syllables were prolonged in the syllable repetition task after surgery.
  • The MR-analysis showed that superior paravermal cerebellar areas likely involved in dysarthria in adults (paravermal lobules HVI, Crus I) were not significantly affected.
  • In children, speech impairments appear to be rare after cerebellar surgery because tumors most commonly affect posterior-inferior and medial parts of the cerebellum while critical cerebellar regions are likely spared.
  • The results suggest a similar localization of speech functions in the cerebellum in children and adults.
  • [MeSH-major] Astrocytoma / epidemiology. Cerebellar Neoplasms / epidemiology. Dysarthria / epidemiology. Dysarthria / physiopathology

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  • (PMID = 15629489.001).
  • [ISSN] 0093-934X
  • [Journal-full-title] Brain and language
  • [ISO-abbreviation] Brain Lang
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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59. Murai N, Kaneko T: [Case of jugular foramen schwannoma associated with tuberous sclerosis]. No Shinkei Geka; 2007 Oct;35(10):1007-11
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  • Her tuberous sclerosis was diagnosed at the age of 9, when she developed hydrocephalus caused by subependymal giant cell astrocytoma near the foramen of Monro, which was treated by surgical resection and VP shunt placement followed by radiation and chemotherapy.
  • Brain MR images revealed a 3 cm enhancing mass extending from the left jugular foramen to the cerebellopontine cistern, accompanied by perifocal edema of the brain stem and cerebellar hemisphere.
  • [MeSH-minor] Adult. Astrocytoma / etiology. Astrocytoma / therapy. Cerebral Ventricle Neoplasms / etiology. Cerebral Ventricle Neoplasms / therapy. Cerebral Ventricles. Female. Humans. Hydrocephalus / etiology. Treatment Outcome

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  • (PMID = 17969337.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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60. Grahovac G, Tomac D, Lambasa S, Zoric A, Habek M: Cerebellar glioblastomas: pathophysiology, clinical presentation and management. Acta Neurochir (Wien); 2009 Jun;151(6):653-7
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  • [Title] Cerebellar glioblastomas: pathophysiology, clinical presentation and management.
  • Glioblastoma multiforme usually affects the cerebral hemispheres with the peak age of onset in the sixth or seventh decade, while cerebellar glioblastoma multiforme is a rare tumour especially in younger patients.
  • Most result from de-differentiation from low grade astrocytoma (secondary glioblastoma) or can develop de novo (primary glioblastoma).
  • We report a 28 year old patient with primary multi-focal cerebellar glioblastoma multiforme and review the pathophysiology, clinical presentation, diagnosis and treatment of cerebellar glioblastomas.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Genetic Predisposition to Disease / genetics. Glioblastoma / pathology. Mutation / genetics. Tumor Suppressor Protein p53 / genetics
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Cerebellum / pathology. Cerebellum / radiography. Cerebellum / surgery. Fatal Outcome. Female. Fourth Ventricle / pathology. Fourth Ventricle / surgery. Headache / etiology. Humans. Hydrocephalus / etiology. Intracranial Hypertension / etiology. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Neurosurgical Procedures / methods. Reoperation. Tomography, X-Ray Computed. Vomiting / etiology

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  • (PMID = 19319469.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Protein p53
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61. Saikali S, Le Strat A, Heckly A, Stock N, Scarabin JM, Hamlat A: Multicentric pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1. Case report and review of the literature. J Neurosurg; 2005 Feb;102(2):376-81
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  • Although the occipital lesion was cured surgically, the cerebellar tumor recurred three times and underwent malignant transformation into an anaplastic oligodendroglioma.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Neurofibromatosis 1 / surgery
  • [MeSH-minor] Adult. Brain / pathology. Brain / surgery. Cell Transformation, Neoplastic / pathology. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellum / pathology. Cerebellum / surgery. Disease Progression. Female. Humans. Image Enhancement. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Occipital Lobe / pathology. Occipital Lobe / surgery. Oligodendroglioma / pathology


62. Horská A, Laclair A, Mohamed M, Wells CT, McNutt T, Cohen KJ, Wharam M, Mahone EM, Kates W: Low cerebellar vermis volumes and impaired neuropsychologic performance in children treated for brain tumors and leukemia. AJNR Am J Neuroradiol; 2010 Sep;31(8):1430-7
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  • [Title] Low cerebellar vermis volumes and impaired neuropsychologic performance in children treated for brain tumors and leukemia.
  • BACKGROUND AND PURPOSE: Injury of the cerebellar vermis may occur in children with brain malignancies.
  • Because the vermis is involved in motor and cognitive functioning, the goal of this prospective longitudinal study was to evaluate treatment-related changes in vermal volumes and neuropsychologic performance in children receiving brain radiation of the cerebellum.
  • In addition to radiation, the presence of brain malignancies and preradiation treatment may be important factors affecting cerebellar vermis tissue.

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  • (PMID = 20448013.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / HD-24061; United States / NCRR NIH HHS / RR / UL1 RR025005; United States / NICHD NIH HHS / HD / HD024061-12; United States / NICHD NIH HHS / HD / P30 HD024061; United States / NINDS NIH HHS / NS / R01 NS04285; United States / NCRR NIH HHS / RR / UL1-RR025005; United States / NCRR NIH HHS / RR / UL1 RR025005-01; United States / NINDS NIH HHS / NS / R01 NS042851-04; United States / NICHD NIH HHS / HD / P30HD024061-16; United States / NINDS NIH HHS / NS / NS042851-04; United States / NICHD NIH HHS / HD / P30 HD024061-12
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS266264; NLM/ PMC3040108
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63. Horbinski C, Hamilton RL, Lovell C, Burnham J, Pollack IF: Impact of morphology, MIB-1, p53 and MGMT on outcome in pilocytic astrocytomas. Brain Pathol; 2010 May;20(3):581-8
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  • Pilocytic astrocytoma (PA) is the most common glioma in the pediatric population.
  • To address this problem, an institutional cohort of 147 PAs (118 with outcome data) from both cerebellar and noncerebellar locations (spine, diencephalon, midbrain, brainstem and cortex) was utilized.
  • In this cohort, the classic biphasic appearance was most common in cerebellar tumors, whereas noncerebellar tumors were predominantly microcystic.
  • Oligodendroglial morphology and the absence of leptomeningeal invasion are adverse histologic factors, but only in cerebellar tumors.
  • [MeSH-major] Astrocytoma / metabolism. Astrocytoma / pathology. Biomarkers, Tumor / metabolism. Brain Neoplasms / metabolism. Brain Neoplasms / pathology. DNA Modification Methylases / physiology. DNA Repair Enzymes / physiology. Ki-67 Antigen / physiology. Tumor Suppressor Protein p53 / physiology. Tumor Suppressor Proteins / physiology

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  • (PMID = 19832838.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / R01 NS37704
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53; 0 / Tumor Suppressor Proteins; EC 2.1.1.- / DNA Modification Methylases; EC 2.1.1.63 / MGMT protein, human; EC 6.5.1.- / DNA Repair Enzymes
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64. Comincini S, Ferrara V, Arias A, Malovini A, Azzalin A, Ferretti L, Benericetti E, Cardarelli M, Gerosa M, Passarin MG, Turazzi S, Bellazzi R: Diagnostic value of PRND gene expression profiles in astrocytomas: relationship to tumor grades of malignancy. Oncol Rep; 2007 May;17(5):989-96
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  • Besides, doppel overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons.
  • In order to address clinical important issues, PRND mRNA expression was investigated in a panel of 111 astrocytoma tissue samples, histologically classified according to the World Health Organization (WHO) criteria (6 grade I pilocytic astrocytomas, 15 grade II low-grade astrocytomas, 26 grade III anaplastic astrocytomas and 64 grade IV glioblastoma multiforme).
  • Extensive differences in PRND gene expression were also found within each grade of malignancy, suggesting that PRND mRNA quantitation might be useful to distinguish astrocytoma subtypes, and important in disease stratification and in the assessment of specific treatment strategies.
  • [MeSH-major] Astrocytoma / genetics. Brain Neoplasms / genetics. Prions / biosynthesis

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  • (PMID = 17390034.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / PRND protein, human; 0 / Prions
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65. Kim SJ, Lee WY, Kim BJ, Kim JY, Hong SB, Tae WS, Seo DW: Isolated tongue tremor after removal of cerebellar pilocytic astrocytoma: Functional analysis with SPECT study. Mov Disord; 2007 Sep 15;22(12):1825-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isolated tongue tremor after removal of cerebellar pilocytic astrocytoma: Functional analysis with SPECT study.
  • We experienced a case of isolated tongue tremor after the removal of a cerebellar pilocytic astrocytoma.
  • [MeSH-minor] Adult. Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Female. Humans. Magnetic Resonance Imaging. Olivary Nucleus / pathology. Olivary Nucleus / radionuclide imaging. Red Nucleus / pathology. Red Nucleus / radionuclide imaging


66. Khongkhatithum C, Visudtibhan A, Chiemchanya S, Visudhiphan P, Sanvivad P, Larbcharoensub N, Phudhicharoenrat S: Multicentric anaplastic astrocytoma in a child. J Clin Neurosci; 2007 Feb;14(2):176-9
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  • [Title] Multicentric anaplastic astrocytoma in a child.
  • We report a rare case of anaplastic astrocytoma with multicentric central nervous system lesions in a 10-year-old girl presenting with a 1-month history of progressive headache and paraparesis.
  • Cranial and spinal magnetic resonance imaging revealed multiple tumour foci within the suprasellar region, cerebellar hemisphere, cervical and thoracic cords.
  • The histological diagnosis was anaplastic astrocytoma based on the WHO classification.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Spinal Cord Neoplasms / pathology

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  • (PMID = 17161293.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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67. Strazzer S, Zucca C, Fiocchi I, Genitori L, Castelli E: Epilepsy and neuropsychologic deficit in a child with cerebellar astrocytoma. J Child Neurol; 2006 Sep;21(9):817-20
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  • [Title] Epilepsy and neuropsychologic deficit in a child with cerebellar astrocytoma.
  • We report the case of a 32-month-old female patient presenting with cerebellar pilocytic astrocytoma with epileptic seizures, psychomotor delay, and severe language delay.
  • Usually, the typical onset of cerebellar tumor is characterized by raised intracranial pressure and cerebellar incoordination.
  • A review of the few cases reported in the literature evidencing epileptic seizures symptomatic of a focal, nondegenerative mass limited to the cerebellum is included.
  • Moreover, a discussion about the cerebellar contribution to nonmotor functions in children is presented, in particular following tumor resection.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Developmental Disabilities / etiology. Epilepsy / etiology

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  • (PMID = 16970895.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants
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68. Benesch M, Eder HG, Sovinz P, Raith J, Lackner H, Moser A, Urban C: Residual or recurrent cerebellar low-grade glioma in children after tumor resection: is re-treatment needed? A single center experience from 1983 to 2003. Pediatr Neurosurg; 2006;42(3):159-64
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  • [Title] Residual or recurrent cerebellar low-grade glioma in children after tumor resection: is re-treatment needed? A single center experience from 1983 to 2003.
  • PURPOSE: The aim of this study was to report on children with cerebellar low-grade glioma (LGG), who were found to have progressive or nonprogresssive residual tumors or tumor recurrence after tumor resection.
  • PATIENTS AND METHODS: Medical records and magnetic resonance imaging (MRI) studies of children (<16 years) with cerebellar LGG were retrospectively analyzed.
  • RESULTS: Of 289 patients with CNS tumors referred between 1983 and 2003, 28 (9.7%) (15 male, 13 female; median age at diagnosis: 71 months) had cerebellar LGG (pilocytic astrocytoma grade I: n = 21; fibrillary astrocytoma grade II: n = 5; mixed hamartoma/pilocytic astrocytoma: n = 1; radiographic diagnosis: n = 1).
  • CONCLUSIONS: A 'wait and see' strategy is justified in patients with nonprogressive recurrent or residual cerebellar LGG after primary tumor resection.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Neoplasm, Residual / surgery

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  • [Copyright] Copyright 2006 S. Karger AG, Basel
  • (PMID = 16636617.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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69. Berg AL, Olson TJ, Feldstein NA: Cerebellar pilocytic astrocytoma with auditory presentation: case study. J Child Neurol; 2005 Nov;20(11):914-5
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  • [Title] Cerebellar pilocytic astrocytoma with auditory presentation: case study.
  • A cerebellar pilocytic astrocytoma was found.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Hearing Loss / etiology

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  • (PMID = 16417863.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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70. Crabtree KL, Arnold PM: Spinal seeding of a pilocytic astrocytoma in an adult, initially diagnosed 18 years previously. Pediatr Neurosurg; 2010;46(1):66-70
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  • [Title] Spinal seeding of a pilocytic astrocytoma in an adult, initially diagnosed 18 years previously.
  • Pilocytic astrocytoma (PA) is a slow-growing, well-circumscribed grade I glioma generally considered benign, with a low recurrence rate and an excellent prognosis following complete surgical resection.
  • We report a 26-year-old male with an intradural extramedullary PA at the thoracolumbar junction following subtotal cerebellar PA resection 18 years previously.
  • [MeSH-major] Astrocytoma / secondary. Brain Neoplasms / pathology. Meningeal Neoplasms / secondary. Neoplasm Seeding. Spinal Cord Neoplasms / secondary

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  • [Copyright] Copyright 2010 S. Karger AG, Basel.
  • (PMID = 20516744.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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71. Francesco F, Maurizio I, Stefano C, Marina S, Ugo S, Massimo S: Trigeminal nerve root entry zone pilocytic astrocytoma in an adult: a rare case of an extraparenchymal tumor. J Neurooncol; 2010 Apr;97(2):285-90
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  • [Title] Trigeminal nerve root entry zone pilocytic astrocytoma in an adult: a rare case of an extraparenchymal tumor.
  • Gliomas in the CPA are rare and quite often are the exophytic extension of primary brain stem or cerebellar tumors.
  • We describe a pilocytic astrocytoma of the CPA that was found to arise from the proximal portion of trigeminal nerve without any anatomic continuity with the brain stem and the cerebellum.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Cranial Nerve Neoplasms / pathology. Trigeminal Nerve Diseases / pathology

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  • (PMID = 19820900.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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72. Komatsu F, Tsugu H, Nonaka M, Tsutsumi M, Yanai F, Yukitake K, Utsunomiya H, Fukushima T: Congenital medulloblastoma with atypical MRI appearance. Pediatr Neurosurg; 2008;44(2):165-8
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  • Preoperatively, vermian tumors, including medulloblastoma, ependymoma, astrocytoma, and hamartomas, were considered in the differential diagnosis.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Magnetic Resonance Imaging. Medulloblastoma / diagnosis

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  • (PMID = 18230934.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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73. Kumar A, Deopujari CE, Biyani N, Mhatre MV: Pediatric cerebellar pilocytic astrocytoma presenting with hemorrhage. Neurol India; 2010 Nov-Dec;58(6):972-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric cerebellar pilocytic astrocytoma presenting with hemorrhage.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Intracranial Hemorrhages / etiology

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  • (PMID = 21150081.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] India
  • [Chemical-registry-number] AU0V1LM3JT / Gadolinium
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74. Rumboldt Z, Camacho DL, Lake D, Welsh CT, Castillo M: Apparent diffusion coefficients for differentiation of cerebellar tumors in children. AJNR Am J Neuroradiol; 2006 Jun-Jul;27(6):1362-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apparent diffusion coefficients for differentiation of cerebellar tumors in children.
  • We hypothesized that cerebellar tumors in children can be differentiated by their ADC values.
  • METHODS: Brain MR imaging studies that included ADC maps were retrospectively reviewed in 32 patients with histologically proved cerebellar neoplasm.
  • CONCLUSION: Assessment of ADC values of enhancing solid tumor is a simple and reliable technique for preoperative differentiation of cerebellar tumors in pediatric patients.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / diagnosis. Astrocytoma / pathology. Child. Child, Preschool. Diagnosis, Differential. Ependymoma / diagnosis. Ependymoma / pathology. Female. Humans. Infant. Male. Medulloblastoma / diagnosis. Medulloblastoma / pathology

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  • [CommentIn] Nat Clin Pract Neurol. 2007 Feb;3(2):78-9 [17279080.001]
  • (PMID = 16775298.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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75. Silvani A: [Experience with the intrathecal use of liposomal cytarabine at the Besta Institute]. Tumori; 2007 May-Jun;93(3):suppl 6-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Astrocytoma / complications. Astrocytoma / drug therapy. Brain Neoplasms / pathology. Breast Neoplasms / pathology. Carcinoma, Non-Small-Cell Lung / complications. Carcinoma, Non-Small-Cell Lung / drug therapy. Cerebellar Neoplasms / pathology. Drug Evaluation. Female. Headache / chemically induced. Humans. Injections, Spinal. Liposomes. Lung Neoplasms / pathology. Male. Neuroectodermal Tumors, Primitive / complications. Neuroectodermal Tumors, Primitive / drug therapy. Palliative Care. Prospective Studies. Retrospective Studies. Treatment Outcome

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  • (PMID = 17679480.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] ita
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Liposomes; 04079A1RDZ / Cytarabine
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76. Habek M, Brinar VV, Rados M, Zadro I, Zarković K: Brain MRI abnormalities in ataxia-telangiectasia. Neurologist; 2008 May;14(3):192-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / pathology. Ataxia Telangiectasia / pathology. Brain / abnormalities. Brain / pathology. Brain Neoplasms / pathology
  • [MeSH-minor] Adult. Age Factors. Atrophy / pathology. Atrophy / physiopathology. Cerebellar Diseases / etiology. Cerebellar Diseases / pathology. Cerebellar Diseases / physiopathology. Cerebral Arteries / pathology. Cerebral Arteries / physiopathology. Disease Progression. Fatal Outcome. Female. Humans. Magnetic Resonance Imaging. Telangiectasis / genetics. Telangiectasis / pathology. Telangiectasis / physiopathology. Tomography, X-Ray Computed


77. Furuse M, Miyatake SI, Kuroiwa T: Cavernous malformation after radiation therapy for astrocytoma in adult patients: report of 2 cases. Acta Neurochir (Wien); 2005 Oct;147(10):1097-101; discussion 1101
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  • [Title] Cavernous malformation after radiation therapy for astrocytoma in adult patients: report of 2 cases.
  • We describe two adult patients with cavernous malformation after irradiation for astrocytoma.
  • Radiation-induced cavernous malformations are rare in adult patients with astrocytoma.
  • One reason why we found two such cases was that these patients had been successfully treated for astrocytoma and had long follow-up periods.
  • [MeSH-major] Astrocytoma / radiotherapy. Blood Vessels / pathology. Blood Vessels / radiation effects. Brain Neoplasms / radiotherapy. Hemangioma, Cavernous, Central Nervous System / etiology. Neoplasms, Radiation-Induced / etiology. Radiotherapy / adverse effects
  • [MeSH-minor] Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / radiotherapy. Dementia / diagnosis. Dementia / etiology. Dementia / physiopathology. Frontal Lobe / blood supply. Frontal Lobe / pathology. Frontal Lobe / radiation effects. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Temporal Lobe / blood supply. Temporal Lobe / pathology. Temporal Lobe / radiation effects. Tomography, X-Ray Computed

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  • (PMID = 16021386.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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78. Villarejo F, de Diego JM, de la Riva AG: Prognosis of cerebellar astrocytomas in children. Childs Nerv Syst; 2008 Feb;24(2):203-10
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  • [Title] Prognosis of cerebellar astrocytomas in children.
  • OBJECTIVE: Our main objective is to review a large series of cerebellar astrocytomas in children and evaluate the outcome of the patients depending on astrocytoma class.
  • The effect of astrocytoma characteristics on the children's prognosis was determined by grouping a series of cerebellar astrocytomas by their location, radiological aspect, size, and histology and determining whether this was related with outcome.
  • MATERIALS AND METHODS: Two hundred and three children with cerebellar astrocytomas were retrospectively reviewed, and their tumors were classified by location, macroscopic radiological appearance, size, and histology.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology

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  • (PMID = 17710415.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
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79. Zorlu F, Selek U, Akyuz C, Ozturk A, Soylemezoglu F, Akalan N: Spinal seeding of a pilocytic astrocytoma following multiple subtotal resections. Pediatr Neurosurg; 2005 Sep-Oct;41(5):248-52
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  • [Title] Spinal seeding of a pilocytic astrocytoma following multiple subtotal resections.
  • We report the case of a 4-year-old girl presenting with spinal and leptomeningeal dissemination following several subtotal resections of cerebellar pilocytic astrocytomas.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Meningeal Neoplasms / secondary. Neoplasm Seeding. Neurosurgical Procedures / adverse effects. Spinal Cord Neoplasms / secondary

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 16195677.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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80. Shamji MF, Vassilyadi M, Lam CH, Montes JL, Farmer JP: Congenital tumors of the central nervous system: the MCH experience. Pediatr Neurosurg; 2009;45(5):368-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Astrocytoma / congenital. Astrocytoma / mortality. Astrocytoma / surgery. Cerebellar Neoplasms / congenital. Cerebellar Neoplasms / mortality. Cerebellar Neoplasms / surgery. Female. Follow-Up Studies. Hospitals, Pediatric / statistics & numerical data. Humans. Infant. Infant, Newborn. Male. Medulloblastoma / congenital. Medulloblastoma / mortality. Medulloblastoma / surgery. Neuroectodermal Tumors, Primitive / congenital. Neuroectodermal Tumors, Primitive / mortality. Neuroectodermal Tumors, Primitive / surgery. Ontario / epidemiology. Retrospective Studies

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  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19907201.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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81. Werbowetski-Ogilvie TE, Seyed Sadr M, Jabado N, Angers-Loustau A, Agar NY, Wu J, Bjerkvig R, Antel JP, Faury D, Rao Y, Del Maestro RF: Inhibition of medulloblastoma cell invasion by Slit. Oncogene; 2006 Aug 24;25(37):5103-12
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  • [Title] Inhibition of medulloblastoma cell invasion by Slit.
  • Invasion of brain tumor cells has made primary malignant brain neoplasms among the most recalcitrant to therapeutic strategies.
  • We tested whether the secreted protein Slit2, which guides the projection of axons and developing neurons, could modulate brain tumor cell invasion.
  • Slit2 inhibited the invasion of medulloblastoma cells in a variety of in vitro models.
  • The effect of Slit2 was inhibited by the Robo ectodomain.
  • Time-lapse videomicroscopy indicated that Slit2 reduced medulloblastoma invasion rate without affecting cell direction or proliferation.
  • Both medulloblastoma and glioma tumors express Robo1 and Slit2, but only medulloblastoma invasion is inhibited by recombinant Slit2 protein.
  • Downregulation of activated Cdc42 may contribute to this differential response.
  • Our findings reinforce the concept that neurodevelopmental cues such as Slit2 may provide insights into brain tumor invasion.

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  • (PMID = 16636676.001).
  • [ISSN] 0950-9232
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA114197-01A2; United States / NEI NIH HHS / EY / EY014576-03; United States / NIGMS NIH HHS / GM / R01 GM070967-02; United States / NEI NIH HHS / EY / R01 EY014576; United States / NIGMS NIH HHS / GM / GM070967-02; United States / NEI NIH HHS / EY / R01 EY014576-03; United States / NCI NIH HHS / CA / CA114197-01A2; United States / NIGMS NIH HHS / GM / R01 GM070967; United States / NCI NIH HHS / CA / R01 CA114197
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Culture Media, Conditioned; 0 / Intercellular Signaling Peptides and Proteins; 0 / Nerve Tissue Proteins; 0 / RNA, Neoplasm; 0 / Receptors, Immunologic; 0 / Recombinant Proteins; 0 / Slit homolog 2 protein; 0 / roundabout protein
  • [Other-IDs] NLM/ NIHMS30537; NLM/ PMC2072874
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82. Klase D, Gottschalk S, Reusche E, Hagel C, Goebel E, Tronnier V, Giese A: Lumbosacral glioblastoma and leptomeningeal gliomatosis complicating the course of a cervicothoracic astrocytoma WHO grade II. Childs Nerv Syst; 2007 Aug;23(8):907-12
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  • [Title] Lumbosacral glioblastoma and leptomeningeal gliomatosis complicating the course of a cervicothoracic astrocytoma WHO grade II.
  • CASE REPORT: The reported female patient underwent sub-total resection of an intra-medullary cervicothoracic astrocytoma classified as WHO grade II in 1984 at the age of 18 months and received local irradiation.
  • Sixteen years later, a small recurrent cervicothoracic tumour was found and spinal seeding to the equine nerve roots and the left cerebellar cortex was apparent on MRI.
  • [MeSH-major] Astrocytoma / complications. Glioblastoma / complications. Meningeal Neoplasms / complications. Spinal Cord Neoplasms / complications

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  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
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  • [Publication-type] Case Reports; Journal Article
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83. Broekman ML, Risselada R, Engelen-Lee J, Spliet WG, Verweij BH: Glioblastoma multiforme in the posterior cranial fossa in a patient with neurofibromatosis type I. Case Rep Med; 2009;2009:757898
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  • The most common brain tumors, found in 15%-20% of NF1 patients, are hypothalamic-optic gliomas, followed by brainstem and cerebellar pilocytic astrocytomas.
  • We present an NF1 patient who developed a high-grade astrocytoma in the posterior fossa and discuss possible pathophysiological mechanisms.

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  • (PMID = 20029672.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2796235
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84. Roujeau T, Machado G, Garnett MR, Miquel C, Puget S, Geoerger B, Grill J, Boddaert N, Di Rocco F, Zerah M, Sainte-Rose C: Stereotactic biopsy of diffuse pontine lesions in children. J Neurosurg; 2007 Jul;107(1 Suppl):1-4
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  • OBJECT: Empirical radiotherapy is the current treatment for children with diffuse pontine lesions that have imaging characteristics of an infiltrative malignant astrocytoma.
  • A histological diagnosis was made in all 24 patients as follows: 22 had a malignant infiltrative astrocytoma, one had a low-grade astrocytoma, and one had a pilocytic astrocytoma.
  • A nonmalignant tumor was identified in two of the 24 patients in whom the imaging findings were characteristic of a malignant infiltrative astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Biopsy, Needle. Brain Stem Neoplasms / pathology. Magnetic Resonance Imaging. Pons / pathology. Stereotaxic Techniques
  • [MeSH-minor] Cerebellar Ataxia / etiology. Chemotherapy, Adjuvant. Child. Child, Preschool. Combined Modality Therapy. Cranial Irradiation. Cranial Nerve Diseases / etiology. Female. Hemiplegia / etiology. Humans. Infant. Male. Neurologic Examination. Postoperative Complications / etiology. Tomography, X-Ray Computed

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  • [CommentIn] J Neurosurg Pediatr. 2008 May;1(5):423; author reply 424-5 [18447684.001]
  • [CommentIn] J Neurosurg Pediatr. 2008 May;1(5):423-4; author reply 424-5 [18536100.001]
  • [CommentIn] J Neurosurg Pediatr. 2008 May;1(5):424; author reply 424-5 [18533336.001]
  • (PMID = 17647306.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Willard VW, Hardy KK, Bonner MJ: Gender differences in facial expression recognition in survivors of pediatric brain tumors. Psychooncology; 2009 Aug;18(8):893-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Astrocytoma / psychology. Astrocytoma / radiotherapy. Brain / radiation effects. Case-Control Studies. Cerebellar Neoplasms / psychology. Cerebellar Neoplasms / radiotherapy. Child. Ependymoma / psychology. Ependymoma / radiotherapy. Female. Humans. Intelligence / radiation effects. Male. Medulloblastoma / psychology. Medulloblastoma / radiotherapy. Neuropsychological Tests. Sex Factors. Social Adjustment


86. Yang BP, Yang CW: Remote cerebellar hemorrhage after craniotomy. Pediatr Neurosurg; 2005 Jan-Feb;41(1):52-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Remote cerebellar hemorrhage after craniotomy.
  • [MeSH-major] Astrocytoma / surgery. Brain Hemorrhage, Traumatic / etiology. Brain Neoplasms / surgery. Craniotomy / adverse effects. Temporal Lobe / surgery

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  • (PMID = 15886515.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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87. Samuelson C, Forman KM, Smith S: Idiopathic thrombocytopenic purpura associated with an astrocytoma. BMJ Case Rep; 2010;2010
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  • [Title] Idiopathic thrombocytopenic purpura associated with an astrocytoma.
  • Urgent computed tomography scan of the head showed a large bleed into a left cerebellar lesion.
  • She underwent treatment with intravenous immunoglobulin (IVIg) and steroids to increase her platelet count, followed by excision of the lesion, which was found to be a benign pilocytic astrocytoma.

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  • (PMID = 22419950.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028124
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88. Mano Y, Kanamori M, Sonoda Y, Kumabe T, Watanabe M, Tominaga T: [A case report of cerebellar pleomorphic xanthoastrocytoma]. No Shinkei Geka; 2009 Jun;37(6):586-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case report of cerebellar pleomorphic xanthoastrocytoma].
  • We report an unusual case of PXA in the cerebellar vermis.
  • Magnetic resonance imaging and computed tomography demonstrated a mass lesion with cyst in the cerebellar vermis.
  • The histological diagnosis was PXA of the cerebellar vermis.
  • This case suggests that PXA should be considered in the differential diagnosis of cystic lesion in the cerebellar vermis.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology

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  • (PMID = 19522287.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 19
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89. Bing F, Kremer S, Lamalle L, Chabardes S, Ashraf A, Pasquier B, Le Bas JF, Krainik A, Grand S: [Value of perfusion MRI in the study of pilocytic astrocytoma and hemangioblastoma: preliminary findings]. J Neuroradiol; 2009 May;36(2):82-7
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  • [Title] [Value of perfusion MRI in the study of pilocytic astrocytoma and hemangioblastoma: preliminary findings].
  • PURPOSE: Pilocytic astrocytomas (PA) and hemangioblastomas (HB) can present the same morphological characteristics on conventional MRI sequences, most usually in the form of a cerebellar cystic mass with a mural nodule that strongly enhances on post-contrast T1 images.
  • [MeSH-major] Astrocytoma / diagnosis. Blood Volume. Brain / blood supply. Brain Neoplasms / diagnosis. Cerebrovascular Circulation. Hemangioblastoma / diagnosis. Magnetic Resonance Imaging / methods


90. Huber JF, Bradley K, Spiegler B, Dennis M: Long-term neuromotor speech deficits in survivors of childhood posterior fossa tumors: effects of tumor type, radiation, age at diagnosis, and survival years. J Child Neurol; 2007 Jul;22(7):848-54
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  • The cerebellum is important for the coordination of fluent speech.
  • The authors studied how childhood cerebellar tumors affect long-term neuromotor speech outcomes, including the relation between outcome and tumor type, radiation, age at diagnosis, and survival years.
  • Videotaped speech samples of child and adult long-term survivors of childhood cerebellar astrocytoma (nonradiated) and medulloblastoma (radiated) tumors and healthy controls were analyzed by 2 speech pathologists for ataxic dysarthria, dysfluency, and speech rate.
  • Medulloblastoma and astrocytoma survivors were each significantly more dysfluent than controls but did not differ from each other.
  • Ataxic dysarthric speech characteristics are more frequent in radiated survivors of medulloblastoma tumors than nonradiated survivors of astrocytoma tumors.
  • Dysfluent and slow speech occur in cerebellar tumor survivors, regardless of tumor type and radiation history.
  • Cerebellar tumors in childhood limit speech rate in adulthood.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Dysarthria / etiology. Infratentorial Neoplasms / complications. Medulloblastoma / complications

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  • (PMID = 17715277.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P01 HD 35946
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
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91. MacKillop E, Thrall DE, Ranck RS, Linder KE, Munana KR: Imaging diagnosis--synchronous primary brain tumors in a dog. Vet Radiol Ultrasound; 2007 Nov-Dec;48(6):550-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / veterinary. Cerebellar Neoplasms / veterinary. Dog Diseases / pathology. Medulloblastoma / veterinary. Neoplasms, Multiple Primary / veterinary. Thalamic Diseases / veterinary

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  • (PMID = 18018727.001).
  • [ISSN] 1058-8183
  • [Journal-full-title] Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
  • [ISO-abbreviation] Vet Radiol Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Kano T, Ikota H, Wada H, Iwasa S, Kurosaki S: A case of an anaplastic ependymoma with gliosarcomatous components. Brain Tumor Pathol; 2009;26(1):11-7
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  • Computed tomography revealed a large cystic lesion with a mural nodule-like mass homogeneously enhanced with contrast medium in the right cerebellum.
  • The tumor was removed, and pathological studies revealed a cerebellar astrocytoma corresponding to World Health Organization grade II.
  • When she was 35 years old, or 6 years after the surgery, magnetic resonance imaging revealed a recurrence of the tumor in the right cerebellum, and subtotal removal of the recurrent tumor was performed.
  • Thereafter, at 39 years of age, or 4 years after radiation therapy, magnetic resonance imaging again revealed a recurrence of the tumor, which was heterogeneously enhanced with gadoliniumdiethylenetriamine pentaacetic acid in the right cerebellum.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Ependymoma / pathology. Gliosarcoma / pathology
  • [MeSH-minor] Adult. Astrocytoma / pathology. Astrocytoma / surgery. Female. Glial Fibrillary Acidic Protein / metabolism. Headache / etiology. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Paraffin Embedding. Tomography, X-Ray Computed

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  • (PMID = 19408092.001).
  • [ISSN] 1861-387X
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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93. de Ribaupierre S, Ryser C, Villemure JG, Clarke S: Cerebellar lesions: is there a lateralisation effect on memory deficits? Acta Neurochir (Wien); 2008 Jun;150(6):545-50; discussion 550
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar lesions: is there a lateralisation effect on memory deficits?
  • BACKGROUND: Until recently, neurosurgeons eagerly removed cerebellar lesions without consideration of future cognitive impairment that might be caused by the resection.
  • In children, transient cerebellar mutism after resection has lead to a diminished use of midline approaches and vermis transection, as well as reduced retraction of the cerebellar hemispheres.
  • The role of the cerebellum in higher cognitive functions beyond coordination and motor control has recently attracted significant interest in the scientific community, and might change the neurosurgical approach to these lesions.
  • The aim of this study was to investigate the specific effects of cerebellar lesions on memory, and to assess a possible lateralisation effect.
  • METHODS: We studied 16 patients diagnosed with a cerebellar lesion, from January 1997 to April 2005, in the "Centre Hospitalier Universitaire Vaudois (CHUV)", Lausanne, Switzerland.
  • RESULTS: Severe memory deficits in at least one modality were identified in a majority (81%) of patients with cerebellar lesions.
  • FINDINGS: These findings are consistent with findings in the literature concerning memory deficits in isolated cerebellar lesions.
  • The high percentage of patients with a cerebellar lesion who demonstrate memory deficits should lead us to assess memory in all patients with cerebellar lesions.
  • [MeSH-major] Amnesia / physiopathology. Cerebellar Neoplasms / physiopathology. Dominance, Cerebral / physiology
  • [MeSH-minor] Adolescent. Adult. Aged. Amnesia, Anterograde / diagnosis. Amnesia, Anterograde / physiopathology. Astrocytoma / diagnosis. Astrocytoma / physiopathology. Astrocytoma / surgery. Cerebellum / physiopathology. Cerebellum / surgery. Female. Follow-Up Studies. Glioblastoma / diagnosis. Glioblastoma / physiopathology. Glioblastoma / surgery. Hemangioblastoma / diagnosis. Hemangioblastoma / physiopathology. Hemangioblastoma / surgery. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / physiopathology. Hemangioma, Cavernous / surgery. Humans. Male. Medulloblastoma / diagnosis. Medulloblastoma / physiopathology. Medulloblastoma / surgery. Memory, Short-Term / physiology. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / physiopathology. Meningeal Neoplasms / surgery. Meningioma / diagnosis. Meningioma / physiopathology. Meningioma / surgery. Middle Aged. Neuropsychological Tests. Postoperative Complications / diagnosis. Postoperative Complications / physiopathology. Verbal Learning / physiology

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  • (PMID = 18512000.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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94. Mezer E, Nischal KK, Nahjawan N, MacKeen LD, Buncic JR: Hemifacial spasm as the initial manifestation of childhood cerebellar astrocytoma. J AAPOS; 2006 Oct;10(5):489-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemifacial spasm as the initial manifestation of childhood cerebellar astrocytoma.

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  • (PMID = 17070492.001).
  • [ISSN] 1091-8531
  • [Journal-full-title] Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • [ISO-abbreviation] J AAPOS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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95. Demir MK, Hakan T, Akinci O, Berkman Z: Primary cerebellar glioblastoma multiforme. Diagn Interv Radiol; 2005 Jun;11(2):83-6
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  • [Title] Primary cerebellar glioblastoma multiforme.
  • Primary glioblastoma multiforme of cerebellar hemispheres in adults is a rare condition.
  • Most of them result from dedifferentiation of astrocytoma to glioblastoma.
  • We present two cases of unusual de novo cerebellar glioblastomas, one of which is the giant-cell variant.
  • [MeSH-major] Cerebellar Neoplasms / radiography. Glioblastoma / radiography

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  • (PMID = 15957093.001).
  • [ISSN] 1305-3825
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
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96. Schiff D: Brain tumor patients with uncertain metastatic potential as organ donors in infancy and childhood. Klin Padiatr; 2010 May;222(3):197; author reply 198
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Astrocytoma / pathology. Astrocytoma / secondary. Astrocytoma / surgery. Blood-Brain Barrier / physiology. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Child. Child, Preschool. Craniotomy / contraindications. Humans. Infant. Medulloblastoma / pathology. Medulloblastoma / secondary. Medulloblastoma / surgery. Neuroectodermal Tumors, Primitive / pathology. Neuroectodermal Tumors, Primitive / secondary. Neuroectodermal Tumors, Primitive / surgery. Risk Factors. Ventriculoperitoneal Shunt / contraindications


97. Huo L, Bi C, Fang J, Wang Y, Zhang M, Chen F: [Microsurgical treatment and prevention of postoperative complications for the fourth ventricle tumors in adults]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2009 Jul;34(7):642-5
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  • Tumors were excised by inferior vermis cerebellar approach or cerebellomedullary fissure approach.
  • [MeSH-major] Astrocytoma / surgery. Cerebral Ventricle Neoplasms / surgery. Fourth Ventricle / surgery. Microsurgery / methods. Postoperative Complications / prevention & control

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  • (PMID = 19648678.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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98. Manley S, Crooks D, Artingstall L, Buxton N, Appleton R, Riordan A, Cleary G, Pizer B: Diffuse central nervous system protoplasmic astrocytoma. Pediatr Blood Cancer; 2010 May;54(5):768-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diffuse central nervous system protoplasmic astrocytoma.
  • Protoplasmic astrocytoma is an extremely rare form of grade II low grade glioma which usually presents as a discrete mass lesion.
  • We describe a 3-year-old female with diffuse protoplasmic astrocytoma with parenchymal involvement and leptomeningeal spread.
  • Three superficial biopsies did not give the diagnosis and this was only confirmed 8 months from presentation from a larger fourth biopsy taken deeper from the cerebellum.
  • To our knowledge this case represents the distinct presentation of protoplasmic astrocytoma presenting as extensive diffuse meningeal disease.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Meningeal Neoplasms / pathology

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  • (PMID = 20049933.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Agir H, Sen C, Muezzinoglu B, Isl E: Report of a radiation-induced leiomyosarcoma arising from the posterior neck. J Craniofac Surg; 2007 Sep;18(5):1018-20
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  • Herein, we report a 48-year-old male patient who developed leiomyosarcoma in his posterior neck region, which was previously radiated due to a cerebellar astrocytoma.
  • [MeSH-minor] Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Humans. Male. Middle Aged

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  • (PMID = 17912075.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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100. Hoffman S, Schellinger KA, Propp JM, McCarthy BJ, Campbell RT, Davis FG: Seasonal variation in incidence of pediatric medulloblastoma in the United States, 1995-2001. Neuroepidemiology; 2007;29(1-2):89-95
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  • There were no significant results for brain tumors overall, or for the other most common pediatric tumor subtypes (pilocytic astrocytoma, other astrocytoma, and ependymoma).
  • [MeSH-major] Cerebellar Neoplasms / epidemiology. Medulloblastoma / epidemiology. Parturition. Seasons

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  • [Copyright] (c) 2007 S. Karger AG, Basel.
  • (PMID = 17925600.001).
  • [ISSN] 1423-0208
  • [Journal-full-title] Neuroepidemiology
  • [ISO-abbreviation] Neuroepidemiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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