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1. Yeaney GA, O'Connor SM, Jankowitz BT, Hamilton RL: A 16-year-old male with a cerebellar mass. Brain Pathol; 2009 Jan;19(1):167-70
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  • [Title] A 16-year-old male with a cerebellar mass.
  • MRI revealed a cystic and solid, enhancing midline cerebellar lesion.
  • An infiltrating component resembling diffuse astrocytoma could be found in areas.
  • The pathologic diagnosis was pleomorphic xanthoastrocytoma (PXA) of the cerebellum.
  • This case is one of sixteen cerebellar PXAs reported in the literature.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis

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  • (PMID = 19076785.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Reticulin; 0 / Vimentin
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2. Neves AM, Thompson G, Carvalheira J, Trindade JC, Rueff J, Caetano JM, Casey JW, Hermouet S: Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma. Brain Res; 2008 Jul 24;1221:108-14
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  • [Title] Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma.
  • We investigated the hypothetical role of human herpesviruses (HHVs) in tumour formation of the cerebellum.
  • Thirty-five samples of pilocytic astrocytoma and 10 control samples of cerebellum from patients who died of unrelated diseases were examined.
  • In summary, EBV was the most frequent HHV detected in pilocytic astrocytoma, but at very low levels.
  • According to the actually accepted threshold the results suggest that EBV cannot be considered responsible for tumorigenesis of pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / virology. Cerebellar Neoplasms / virology. DNA, Viral / genetics. Herpesviridae / genetics. Herpesviridae Infections / complications. Herpesviridae Infections / genetics

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  • (PMID = 18565499.001).
  • [ISSN] 0006-8993
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA, Viral; EC 2.7.7.- / DNA Polymerase III; EC 2.7.7.- / DNA polymerase A
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3. Cuellar-Baena S, Morales JM, Martinetto H, Calvar J, Sevlever G, Castellano G, Cerdá-Nicolás M, Celda B, Monleon D: Comparative metabolic profiling of paediatric ependymoma, medulloblastoma and pilocytic astrocytoma. Int J Mol Med; 2010 Dec;26(6):941-8
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  • [Title] Comparative metabolic profiling of paediatric ependymoma, medulloblastoma and pilocytic astrocytoma.
  • The most common paediatric brain tumours include ependymomas, cerebellar astrocytomas and medulloblastomas.
  • Tumour types include ependymoma, medulloblastoma and pilocytic astrocytoma.


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4. Jea A, Coscarella E, Chintagumpala M, Bhattacharjee M, Whitehead WE, Curry DJ, Luerssen TG: Medulloblastoma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors in a child: case report. J Neurosurg Pediatr; 2010 Feb;5(2):149-54
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  • [Title] Medulloblastoma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors in a child: case report.
  • Brain MR imaging demonstrated a heterogeneously enhancing mixed solid/cystic mass of the left cerebellar hemisphere and a larger, midline, more homogeneously enhancing lesion of the superior vermis.
  • Pathological examination revealed the left cerebellar and superior vermian lesions to be a juvenile pilocytic astrocytoma and a medulloblastoma, respectively.
  • To the best of the authors' knowledge, they describe the first known pediatric case in which a medulloblastoma and a juvenile pilocytic astrocytoma presented as synchronous primary brain tumors.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebellar Neoplasms / pathology. Medulloblastoma / pathology


5. Vaquero E, Gómez CM, Quintero EA, González-Rosa JJ, Márquez J: Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor. Behav Brain Funct; 2008;4:18
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  • [Title] Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor.
  • BACKGROUND: This study was realized thanks to the collaboration of children and adolescents who had been resected from cerebellar tumors.
  • The astrocytoma group (CE, n = 13) did not receive additional treatments.
  • The Astrocytoma group also showed executive deficits in digits span, semantic fluency (animal category) and moderate to slight deficit in Stroop (word and colour) tests.
  • In the astrocytoma group, the tumor's localization and dentate affectation showed different profile and level of impairment: moderate to slight for vermal and hemispheric patients respectively.
  • CONCLUSION: Results suggest a differential prefrontal-like deficit due to cerebellar lesions and/or cerebellar-frontal diaschisis, as indicate the results in astrocytoma group (without treatments), that also can be generated and/or increased by treatments in the medulloblastoma group.
  • The results are also discussed in the context of the Cerebellar Cognitive Affective Syndrome.

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  • (PMID = 18412947.001).
  • [ISSN] 1744-9081
  • [Journal-full-title] Behavioral and brain functions : BBF
  • [ISO-abbreviation] Behav Brain Funct
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2362115
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6. Jacob K, Albrecht S, Sollier C, Faury D, Sader E, Montpetit A, Serre D, Hauser P, Garami M, Bognar L, Hanzely Z, Montes JL, Atkinson J, Farmer JP, Bouffet E, Hawkins C, Tabori U, Jabado N: Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours. Br J Cancer; 2009 Aug 18;101(4):722-33
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  • [Title] Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours.
  • We also establish that it is site specific as it occurs in the majority of cerebellar JPA (24 of 30 - 80%) followed by brainstem, hypothalamic/optic pathway JPA (10 of 16 - 62.5%) and is rare in hemispheric JPA (1 of 7 - 14%).
  • [MeSH-major] Astrocytoma / genetics. Biomarkers, Tumor / genetics. Brain Neoplasms / genetics. Chromosomes, Human, Pair 7 / genetics

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  • (PMID = 19603027.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carrier Proteins; EC 2.7.1.- / HIPK2 protein, human; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf; EC 2.7.11.24 / Mitogen-Activated Protein Kinases
  • [Other-IDs] NLM/ PMC2736806
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7. Castillo M: Stem cells, radial glial cells, and a unified origin of brain tumors. AJNR Am J Neuroradiol; 2010 Mar;31(3):389-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / etiology. Brain Neoplasms / etiology. Medulloblastoma / etiology. Neuroglia / pathology. Stem Cells / pathology
  • [MeSH-minor] Cerebellar Neoplasms / etiology. Cerebellar Neoplasms / pathology. Ependymoma / etiology. Ependymoma / pathology. Humans

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  • (PMID = 19797796.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Editorial
  • [Publication-country] United States
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8. Gheri CF, Buccoliero AM, Pansini G, Castiglione F, Garbini F, Moncini D, Maccari C, Mennonna P, Pellicanò G, Ammannati F, Taddei GL: Lipoastrocytoma: Case report and review of the literature. Neuropathology; 2010 Oct;30(5):553-8
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  • We report the case of an astrocytoma involving the upper part of the cerebellar-pontine angle and the right portion of the clivus starting from the brainstem with a diffuse lipomatous component in a 39 year-old man.
  • MRI revealed a ponto-cerebellar lesion that showed irregular enhancement after contrast administration.
  • Histologically the tumor showed the classical histology of low-grade astrocytoma and a portion of the lesion was composed of lipid-laden cells.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Lipomatosis / pathology
  • [MeSH-minor] Adult. Brain Stem / pathology. Cerebellum / pathology. Humans. Male

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  • [Copyright] © 2010 Japanese Society of Neuropathology.
  • (PMID = 20113404.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Australia
  • [Keywords] NOTNLM ; lipid vacuole / lipoastrocytoma / lipomatous / low grade astrocytoma
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9. El-Bahy K: Telovelar approach to the fourth ventricle: operative findings and results in 16 cases. Acta Neurochir (Wien); 2005 Feb;147(2):137-42; discussion 142
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  • Subtotal removal was achieved in the remaining patients (31.25%); three ependymomas, one medulloblastoma, and one anaplastic astrocytoma.
  • Cerebellar mutism was not observed in any patient and there was no mortality.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellum / pathology. Cerebellum / surgery. Fourth Ventricle / pathology. Fourth Ventricle / surgery. Neurosurgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / pathology. Astrocytoma / surgery. Cerebellar Ataxia / etiology. Cerebellar Ataxia / pathology. Cerebellar Ataxia / physiopathology. Child. Choroid Plexus / pathology. Choroid Plexus / surgery. Cranial Fossa, Posterior / surgery. Dermoid Cyst / pathology. Dermoid Cyst / surgery. Ependymoma / pathology. Ependymoma / surgery. Female. Humans. Magnetic Resonance Imaging. Male. Medulloblastoma / pathology. Medulloblastoma / surgery. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Papilloma, Choroid Plexus / pathology. Papilloma, Choroid Plexus / surgery. Postoperative Complications / etiology. Postoperative Complications / pathology. Postoperative Complications / physiopathology. Retrospective Studies. Treatment Outcome

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  • (PMID = 15605202.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Austria
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10. El Ayachi I, Baeza N, Fernandez C, Colin C, Scavarda D, Pesheva P, Figarella-Branger D: KIAA0510, the 3'-untranslated region of the tenascin-R gene, and tenascin-R are overexpressed in pilocytic astrocytomas. Neuropathol Appl Neurobiol; 2010 Aug;36(5):399-410
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  • [MeSH-major] Astrocytoma / genetics. Cerebellar Neoplasms / genetics. Gene Expression Regulation, Neoplastic. Tenascin / genetics

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  • (PMID = 20202125.001).
  • [ISSN] 1365-2990
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 3' Untranslated Regions; 0 / Tenascin; 147604-77-1 / tenascin R
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11. Happle C, Wetzke M, Hermann EJ, Krauss JK, Hartmann H, Lücke T: ['Cases against KiSS': a diagnostic algorithm for children with torticollis]. Klin Padiatr; 2009 Dec;221(7):430-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Algorithms. Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Cervical Vertebrae. Ganglioglioma / diagnosis. Magnetic Resonance Imaging. Neoplasms, Second Primary / diagnosis. Spinal Diseases / diagnosis. Torticollis / etiology

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  • [Copyright] (c) Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 20013566.001).
  • [ISSN] 1439-3824
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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12. Udayakumaran S, Ben Sira L, Constantini S: Chronic uncal herniation secondary to posterior fossa shunting: case report and literature review. Childs Nerv Syst; 2010 Feb;26(2):267-71
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  • CASE REPORT: A 15-year-old girl had a resection of a cerebellar pilocytic astrocytoma at 5 years of age.
  • Comparing the case reports in the literature with our case, we postulate that chronic uncal herniation is a complication of shunting of a posterior fossa fluid cavity in children, many of them with Dandy-Walker syndrome and/or other cerebellar cystic formations.
  • [MeSH-minor] Adolescent. Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Chronic Disease. Female. Humans. Intracranial Pressure. Magnetic Resonance Imaging. Temporal Lobe / diagnostic imaging. Temporal Lobe / pathology. Temporal Lobe / surgery. Tomography, X-Ray Computed

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  • (PMID = 19915852.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 15
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13. Kim SH, Kim TS: Squash smear findings of eosinophilic granular bodies in pilocytic astrocytoma. Acta Cytol; 2005 Jan-Feb;49(1):112-4
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  • [Title] Squash smear findings of eosinophilic granular bodies in pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Cytoplasmic Granules / pathology. Eosinophils / pathology. Specimen Handling / methods

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  • (PMID = 15717769.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Letter
  • [Publication-country] United States
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14. Rett D: Gaze-evoked nystagmus: a case report and literature review. Optometry; 2007 Sep;78(9):460-4
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  • Magnetic resonance imaging found a large, brainstem astrocytoma in the cerebellar-pontine angle.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Brain Stem. Fixation, Ocular. Nystagmus, Pathologic / etiology

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  • (PMID = 17765857.001).
  • [ISSN] 1529-1839
  • [Journal-full-title] Optometry (St. Louis, Mo.)
  • [ISO-abbreviation] Optometry
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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15. Li JY, Wang H, May S, Song X, Fueyo J, Fuller GN, Wang H: Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas. J Neurooncol; 2008 May;88(1):11-7
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  • [Title] Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas.
  • The c-Jun NH2-terminal kinase (JNK), which belongs to mitogen-activated protein kinase family, plays a major role in apoptosis in various cell types.
  • pJNK expression was not detected in the astrocytes or oligodendrocytes of any of 10 normal cerebral and cerebellar brain tissue samples.
  • [MeSH-minor] Astrocytoma / drug therapy. Astrocytoma / pathology. Blotting, Western. Cells, Cultured. Enzyme Activation / physiology. Glioblastoma / drug therapy. Glioblastoma / pathology. Gliosarcoma / drug therapy. Gliosarcoma / pathology. Humans. Immunohistochemistry. Oligodendroglioma / drug therapy. Oligodendroglioma / pathology


16. Stüer C, Vilz B, Majores M, Becker A, Schramm J, Simon M: Frequent recurrence and progression in pilocytic astrocytoma in adults. Cancer; 2007 Dec 15;110(12):2799-808
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frequent recurrence and progression in pilocytic astrocytoma in adults.
  • BACKGROUND: Most pilocytic astrocytomas (piloA) are benign growths (World Health Organization [WHO] grade 1) of the deep midline structures, the brainstem, and the cerebellum.
  • RESULTS: There were 20 patients (45%) with supratentorial lobar piloA (including 10 temporal/temporomesial tumors, 5 parietal tumors, 3 insular tumors, 1 frontal tumor, and 1 occipital tumors), 12 patients with cerebellar piloA, 7 patients with brainstem piloA, 2 patients with opticochiasmatic PiloA, 1 patient with intramedullary piloA, and 2 patients with piloA of the basal ganglia.
  • [MeSH-major] Astrocytoma / pathology. Astrocytoma / radiography. Brain Neoplasms / pathology

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  • [CommentIn] Nat Clin Pract Neurol. 2008 Jun;4(6):296-7 [18414467.001]
  • (PMID = 17973253.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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17. Bonner MJ, Hardy KK, Willard VW, Anthony KK, Hood M, Gururangan S: Social functioning and facial expression recognition in survivors of pediatric brain tumors. J Pediatr Psychol; 2008 Nov-Dec;33(10):1142-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Arthritis, Juvenile / psychology. Astrocytoma / psychology. Cerebellar Neoplasms / psychology. Child. Ependymoma / psychology. Female. Humans. Intelligence. Male. Medulloblastoma / psychology. Personal Construct Theory. Social Behavior Disorders / diagnosis. Social Behavior Disorders / psychology

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  • (PMID = 18390896.001).
  • [ISSN] 1465-735X
  • [Journal-full-title] Journal of pediatric psychology
  • [ISO-abbreviation] J Pediatr Psychol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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18. Deshmukh H, Yeh TH, Yu J, Sharma MK, Perry A, Leonard JR, Watson MA, Gutmann DH, Nagarajan R: High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas. Oncogene; 2008 Aug 7;27(34):4745-51
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  • [MeSH-major] Astrocytoma / genetics. Carrier Proteins / genetics. Cerebellar Neoplasms / genetics. Gene Amplification. Gene Expression Profiling / methods. Oligonucleotide Array Sequence Analysis / methods. Protein-Serine-Threonine Kinases / genetics

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  • (PMID = 18408760.001).
  • [ISSN] 1476-5594
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Carrier Proteins; EC 2.7.1.- / HIPK2 protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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19. Zuzak TJ, Poretti A, Drexel B, Zehnder D, Boltshauser E, Grotzer MA: Outcome of children with low-grade cerebellar astrocytoma: long-term complications and quality of life. Childs Nerv Syst; 2008 Dec;24(12):1447-55
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  • [Title] Outcome of children with low-grade cerebellar astrocytoma: long-term complications and quality of life.
  • OBJECTS: To study the long-term outcome of surgically treated low-grade cerebellar astrocytomas in children.
  • CONCLUSION: Childhood low-grade cerebellar astrocytomas have an excellent cure rate by tumor surgery alone.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Quality of Life

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  • (PMID = 18690461.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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20. Comincini S, Chiarelli LR, Zelini P, Del Vecchio I, Azzalin A, Arias A, Ferrara V, Rognoni P, Dipoto A, Nano R, Valentini G, Ferretti L: Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells. Oncol Rep; 2006 Dec;16(6):1325-32
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  • Besides, Dpl overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons.
  • In this study the doppel gene (PRND) mRNA and protein expression in PRT-HU2 and IPDDC-A2 astrocytoma-derived cell lines was investigated.
  • Northern blot analysis revealed two equally abundant PRND mRNA isoforms, while real-time PCR, on nuclear and cytoplasmic RNA fractions, and cRNA in situ hybridization, on astrocytoma cells and bioptical specimens, showed a nuclear retention of PRND transcripts.
  • [MeSH-major] Astrocytoma / metabolism. Brain Neoplasms / metabolism. Cell Nucleus / metabolism. Prions / biosynthesis. RNA, Messenger / metabolism

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  • (PMID = 17089057.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / PRND protein, human; 0 / Prions; 0 / RNA, Messenger
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21. Rueckriegel SM, Driever PH, Blankenburg F, Lüdemann L, Henze G, Bruhn H: Differences in supratentorial damage of white matter in pediatric survivors of posterior fossa tumors with and without adjuvant treatment as detected by magnetic resonance diffusion tensor imaging. Int J Radiat Oncol Biol Phys; 2010 Mar 1;76(3):859-66
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  • PATIENTS AND METHODS: Seventeen medulloblastoma (MB) patients who had received surgery and adjuvant treatment, 13 pilocytic astrocytoma (PA) patients who had been treated only with surgery, and age-matched healthy control subjects underwent magnetic resonance imaging on a 3-Tesla system.
  • RESULTS: Compared with control subjects, FA values of MB patients were significantly decreased in the cerebellar midline structures, in the frontal lobes, and in the callosal body.
  • Fractional anisotropy values of the PA patients were not only decreased in cerebellar hemispheric structures as expected, but also in supratentorial parts of the brain, with a distribution similar to that in MB patients.
  • CONCLUSIONS: Neurotoxic mechanisms that are present in PA patients (e.g., internal hydrocephalus and damaged cerebellar structures affecting neuronal circuits) contribute significantly to the alteration of supratentorial white matter in pediatric posterior fossa tumor patients.
  • [MeSH-major] Astrocytoma. Brain / pathology. Diffusion Magnetic Resonance Imaging / methods. Infratentorial Neoplasms. Medulloblastoma. Survivors
  • [MeSH-minor] Adolescent. Anisotropy. Axons. Case-Control Studies. Cerebellum / drug effects. Cerebellum / pathology. Cerebellum / radiation effects. Chemotherapy, Adjuvant / adverse effects. Child. Child, Preschool. Cranial Irradiation / adverse effects. Female. Humans. Leukoencephalopathies / etiology. Leukoencephalopathies / pathology. Male. Radiotherapy, Adjuvant / adverse effects

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  • [Copyright] Copyright (c) 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19540067.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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22. Rafique MZ, Ahmad MN, Yaqoob N, Ahsan H: Diffuse bilateral thalamic astrocytoma. J Coll Physicians Surg Pak; 2007 Mar;17(3):170-2
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  • [Title] Diffuse bilateral thalamic astrocytoma.
  • Diffuse astrocytoma with bilateral thalamic involvement is extremely rare.
  • Biopsy showed grade III Astrocytoma with bilateral thalamic involvement.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Thalamic Diseases / pathology

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  • (PMID = 17374306.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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23. Okamoto H, Mineta T, Ueda S, Nakahara Y, Shiraishi T, Tamiya T, Tabuchi K: Detection of JC virus DNA sequences in brain tumors in pediatric patients. J Neurosurg; 2005 Apr;102(3 Suppl):294-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Antigens, Viral, Tumor / genetics. Astrocytoma / pathology. Astrocytoma / virology. Base Sequence. Blotting, Southern. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / virology. Cerebral Ventricle Neoplasms / pathology. Cerebral Ventricle Neoplasms / virology. Child. Child, Preschool. Ependymoma / pathology. Ependymoma / virology. Female. Humans. Infant. Male. Medulloblastoma / pathology. Medulloblastoma / virology. Papilloma, Choroid Plexus / pathology. Papilloma, Choroid Plexus / virology. Polymerase Chain Reaction. Supratentorial Neoplasms / pathology. Supratentorial Neoplasms / virology

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  • (PMID = 15881753.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Viral, Tumor; 0 / DNA, Viral
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24. Ramírez-Zamora A, Biller J: Brainstem cavernous malformations: a review with two case reports. Arq Neuropsiquiatr; 2009 Sep;67(3B):917-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Pregnancy. Radiotherapy / adverse effects

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  • (PMID = 19838533.001).
  • [ISSN] 1678-4227
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 40
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25. Battaglia F, Uro-Coste E, Delisle MB, Tannier C: [Radiation-induced cavernoma: two cases]. Rev Neurol (Paris); 2008 May;164(5):468-71
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  • The first case was a 55-year-old man given radiation and chemotherapy for frontal astrocytoma at the age of 46.
  • [MeSH-minor] Adult. Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Cerebral Hemorrhage / pathology. Cerebral Ventricles / pathology. Female. Histocytochemistry. Humans. Magnetic Resonance Imaging. Male. Medulloblastoma / radiotherapy. Middle Aged. Pons / pathology

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  • (PMID = 18555880.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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26. Dunn IF, Agarwalla PK, Papanastassiou AM, Butler WE, Smith ER: Multiple pilocytic astrocytomas of the cerebellum in a 17-year-old patient with neurofibromatosis type I. Childs Nerv Syst; 2007 Oct;23(10):1191-4
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  • [Title] Multiple pilocytic astrocytomas of the cerebellum in a 17-year-old patient with neurofibromatosis type I.
  • The most common of these are hypothalamic-optic gliomas, followed by brainstem and cerebellar pilocytic astrocytomas.
  • The most frequent combination in NFI patients with more than one pilocytic astrocytoma is optic tract/hypothalamic and brainstem.
  • This report presents the first documented case, to our knowledge, of multiple pilocytic astrocytomas in the cerebellum of a patient with NF1.
  • CONCLUSION: The finding of multiple cerebellar pilocytic astrocytomas in a patient with NF1 is important because it expands the spectrum of presentations for patients with NF1 and also highlights specific diagnostic and therapeutic challenges faced by the treating physicians.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Neurofibromatosis 1 / pathology

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  • (PMID = 17457593.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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27. Battaglia S, Albini Riccioli L, Zucchelli M, Leonardi M: 3 Tesla MR Study of Cerebellar Medulloblastoma. Neuroradiol J; 2007 Jan 31;19(6):722-6
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  • [Title] 3 Tesla MR Study of Cerebellar Medulloblastoma.
  • Medulloblastoma belongs to the group of highly malignant neuroepithelial tumours and is the commonest tumour in childhood (average age nine years) followed by astrocytoma 1.
  • Medulloblastoma usually arises in the posterior fossa, namely the cerebellar vermis, and more seldom in the fourth ventricle, supratentorium and spinal cord.
  • We describe the 3 Tesla magnetic resonance (MR) features of a medulloblastoma located in the right cerebellar hemisphere adhering to the tentorium in a 16-year-old male.

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  • (PMID = 24351298.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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28. Toyoda T, Ochiai K, Hatai H, Murakami M, Ono E, Kimura T, Umemura T: Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma. Vet Pathol; 2006 May;43(3):294-301
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  • [Title] Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma.
  • Fowl glioma-inducing virus (FGV), which belongs to subgroup A of avian leukosis virus (ALV), shows tumorigenicity and pathogenicity, mainly in the nervous system, and causes astrocytoma and perineurioma.
  • Apart from these neoplasms, cerebellar anomaly was found in chickens infected with FGV in ovo.
  • The study reported here describes the morphologic characteristics of the affected cerebellum.
  • The cerebellar anomaly included diffuse depletion of granular cells of the internal granular layer (IGL), remnants of the external granular layer (EGL), and disorganization of the Purkinje cell layer.
  • These cerebellar changes were observed in all birds except one.
  • These results suggested that the cerebellar anomaly was hypoplasia, principally resulting from the apoptosis of granular cells in the EGL and ML caused by FGV infection and that the cell loss induced obstruction of granular cell migration and disarrangement of Bergmann's fibers in the ML.
  • [MeSH-major] Avian Leukosis Virus / pathogenicity. Cerebellar Diseases / veterinary. Cerebellum / pathology. Glioma / veterinary. Poultry Diseases / pathology. Poultry Diseases / virology

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  • (PMID = 16672576.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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29. Gunny RS, Hayward RD, Phipps KP, Harding BN, Saunders DE: Spontaneous regression of residual low-grade cerebellar pilocytic astrocytomas in children. Pediatr Radiol; 2005 Nov;35(11):1086-91
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  • [Title] Spontaneous regression of residual low-grade cerebellar pilocytic astrocytomas in children.
  • BACKGROUND: Cerebellar low-grade astrocytomas (CLGAs) of childhood are benign tumours and are usually curable by surgical resection alone or combined with adjuvant radiotherapy.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Magnetic Resonance Imaging / methods. Neoplasm Recurrence, Local / pathology. Neoplasm Regression, Spontaneous / pathology. Risk Assessment / methods

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  • (PMID = 16047140.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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30. Bassi R, Anelli V, Giussani P, Tettamanti G, Viani P, Riboni L: Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors. Glia; 2006 Apr 15;53(6):621-30
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  • [Title] Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors.
  • The mitogenic role of sphingosine-1-phosphate (S1P) and its involvement in basic fibroblast growth factor (bFGF)-induced proliferation were examined in primary cultures of cerebellar astrocytes.
  • These results support the view that S1P exerted a mitogenic effect on cerebellar astrocytes extracellularly, most likely through cell surface S1P receptors.
  • In agreement, mRNAs for S1P1, S1P2, and S1P3 receptors are expressed in cerebellar astrocytes (Anelli et al., 2005.
  • Cerebellum 1:129-135), efficiently inhibited S1P-induced proliferation.
  • [MeSH-major] Astrocytes / metabolism. Cell Proliferation / drug effects. Cerebellum / metabolism. Fibroblast Growth Factor 2 / pharmacology. GTP-Binding Protein alpha Subunits, Gi-Go / metabolism. Lysophospholipids / metabolism. Receptors, Lysosphingolipid / metabolism. Sphingosine / analogs & derivatives
  • [MeSH-minor] Animals. Animals, Newborn. Astrocytoma / metabolism. Astrocytoma / physiopathology. Brain Neoplasms / metabolism. Brain Neoplasms / physiopathology. Cell Transformation, Neoplastic / metabolism. Cells, Cultured. Ceramides / metabolism. Ceramides / pharmacology. DNA Replication / drug effects. DNA Replication / physiology. Enzyme Inhibitors / pharmacology. Extracellular Fluid / drug effects. Extracellular Fluid / metabolism. Extracellular Signal-Regulated MAP Kinases / drug effects. Extracellular Signal-Regulated MAP Kinases / metabolism. Gliosis / metabolism. Gliosis / physiopathology. Mitosis / drug effects. Mitosis / physiology. Phosphotransferases (Alcohol Group Acceptor) / antagonists & inhibitors. Phosphotransferases (Alcohol Group Acceptor) / metabolism. Rats. Signal Transduction / drug effects. Signal Transduction / physiology

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  • (PMID = 16470810.001).
  • [ISSN] 0894-1491
  • [Journal-full-title] Glia
  • [ISO-abbreviation] Glia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ceramides; 0 / Enzyme Inhibitors; 0 / Lysophospholipids; 0 / Receptors, Lysosphingolipid; 103107-01-3 / Fibroblast Growth Factor 2; 26993-30-6 / sphingosine 1-phosphate; EC 2.7.1.- / Phosphotransferases (Alcohol Group Acceptor); EC 2.7.1.- / sphingosine kinase; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 3.6.5.1 / GTP-Binding Protein alpha Subunits, Gi-Go; NGZ37HRE42 / Sphingosine
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31. Hope AJ, Mansur DB, Tu PH, Simpson JR: Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma. Childs Nerv Syst; 2006 Sep;22(9):1201-7
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  • [Title] Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma.
  • DISCUSSION: In this study, we report the case of a 15-year-old boy treated for medulloblastoma with surgery and craniospinal radiotherapy, who developed a meningioma 18 years after initial treatment and subsequently an anaplastic astrocytoma 23 years after primary treatment.
  • The patient is currently alive but with recurrent astrocytoma after a complete remission on temozolomide monotherapy.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / radiotherapy. Cranial Irradiation / adverse effects. Medulloblastoma / radiotherapy. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Neoplasms, Radiation-Induced / diagnosis. Neoplasms, Second Primary / diagnosis

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  • (PMID = 16570196.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 40
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32. Taraszewska A, Czernicki Z, Andrychowski J: Hemosiderin pigmentation of tumour cells in cerebellar pilocytic astrocytoma associated with post-traumatic hemorrhage in adults. Folia Neuropathol; 2005;43(3):172-7
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  • [Title] Hemosiderin pigmentation of tumour cells in cerebellar pilocytic astrocytoma associated with post-traumatic hemorrhage in adults.
  • The pilocytic astrocytoma is only rarely associated with gross intratumoral hemorrhage despite rich vasculature and blood vessel changes, accompanied often by perivascular depots of hemosiderin.
  • We report an unusual case of pigmented cerebellar pilocytic astrocytoma presenting with posttraumatic hemorrhage in a 38-year-old man with no history related to the tumor.
  • CT and MRI examination after head injury demonstrated unexpectedly the cystic lesion of 2 cm in diameter in the region of the right cerebellar hemisphere and vermis.
  • Histopathological examination revealed pilocytic astrocytoma tissue with broad hemorrhagic changes and with an unusual pattern of massive pigmentation of the cytoplasm of pilocytic astrocytes, consistent with hemosiderosis.
  • To our knowledge, this is the first reported case of pigmented pilocytic astrocytoma exhibiting extensive intracellular hemosiderin deposition.

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  • (PMID = 16245213.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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33. Masri A, Bakri FG, Assaf A, Musharbash A, Haroun AA, Zak I: Intra-axial dermoid tumor mimicking pilocytic astrocytoma. Childs Nerv Syst; 2009 Apr;25(4):395-6
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  • [Title] Intra-axial dermoid tumor mimicking pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Dermoid Cyst / pathology

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  • [CommentOn] Childs Nerv Syst. 2008 Jan;24(1):157-9 [17657495.001]
  • [Cites] Childs Nerv Syst. 2008 Jan;24(1):157-9 [17657495.001]
  • (PMID = 19184043.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Germany
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34. Johnson AH, Jordan C, Mazewski CM: Off-therapy headaches in pediatric brain tumor patients: a retrospective review. J Pediatr Oncol Nurs; 2009 Nov-Dec;26(6):354-61
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  • In all, 81 charts were reviewed from which headaches in 3 subtypes of tumors were identified (29 medulloblastomas, 36 cerebellar juvenile pilocytic astrocytomas [JPAs], and 16 craniopharyngiomas).
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Craniopharyngioma / complications. Headache / etiology. Medulloblastoma / complications. Pituitary Neoplasms / complications

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  • (PMID = 19687465.001).
  • [ISSN] 1532-8457
  • [Journal-full-title] Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses
  • [ISO-abbreviation] J Pediatr Oncol Nurs
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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35. Daglioglu E, Ergungor F, Hatipoglu HG, Okay O, Dalgic A, Orhan G, Unal T: Cerebral leukoencephalopathy with calcifications and cysts operated for signs of increased intracranial pressure: case report. Surg Neurol; 2009 Aug;72(2):177-81
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  • It should be differentiated from FD or bilateral striopallidodentate calcinosis and astrocytoma.
  • CASE DESCRIPTION: We report a sporadic case operated for signs of increased ICP and cerebellar cystic mass.
  • The patient had symmetric bilateral cerebral and cerebellar calcifications, white matter edema, and a secondary thalamic cyst as well.
  • After resection of the cerebellar mass, clinical picture returned to normal and edematous findings on MRI resolved in addition to a decrease in size of the thalamic lesion on follow-up.
  • [MeSH-major] Calcinosis / diagnosis. Central Nervous System Cysts / diagnosis. Cerebellar Diseases / complications. Cerebellar Diseases / diagnosis. Cerebellum / pathology. Intracranial Hypertension / etiology. Intracranial Hypertension / surgery

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  • (PMID = 18514290.001).
  • [ISSN] 1879-3339
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Rønning C, Sundet K, Due-Tønnessen B, Lundar T, Helseth E: Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood. Pediatr Neurosurg; 2005 Jan-Feb;41(1):15-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood.
  • Traditionally, the cerebral hemispheres have been regarded as the region of the brain responsible for cognitive functions, while the cerebellum has been considered to be primarily involved in motor functions.
  • Recent studies focus also on the possible involvement of the cerebellum in neurocognitive functions.
  • The aim of this study was to determine the neuropsychological profile of young adults treated for a posterior fossa tumor in childhood and look for possible support for the presence of the so-called 'cerebellar cognitive affective syndrome' in these patients.
  • The astrocytoma group (n = 12) had been treated for a low-grade cerebellar astrocytoma with surgery alone (mean age at surgery was 8.6 years and mean age at neuropsychological testing was 23.5 years).
  • Nonetheless, the astrocytoma group also had impaired scores compared with standard norms on measures of motor speed, attention and executive function.
  • No significant correlation between age at time of treatment and grade of neuropsychological impairment was found in the astrocytoma group, though there was a tendency that young age at time of treatment correlated with better outcome on IQ measures.
  • CONCLUSIONS: Persistent cognitive dysfunction was detected in patients treated for posterior fossa medulloblastoma and cerebellar astrocytoma.
  • The astrocytoma group was treated with surgery alone, indicating that a cerebellar lesion can result in cognitive dysfunction.
  • Thus, this study gives support to the existence of the cerebellar cognitive affective syndrome.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Cerebellum / physiopathology. Cerebellum / surgery. Cognition Disorders / etiology. Medulloblastoma / surgery

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 15886508.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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37. Turgut M: Transient cerebellar mutism in childhood. Childs Nerv Syst; 2007 May;23(5):477
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transient cerebellar mutism in childhood.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Medulloblastoma / surgery. Mutism / etiology. Postoperative Complications / psychology

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  • [CommentOn] Childs Nerv Syst. 2006 Feb;22(2):132-8 [16155765.001]
  • [Cites] Br J Neurosurg. 2001 Feb;15(1):47-50 [11303661.001]
  • [Cites] Childs Nerv Syst. 2006 Feb;22(2):132-8 [16155765.001]
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  • (PMID = 17384951.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Germany
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38. Trivedi A, Hiran S: Calcified epidural hematoma in pediatric age group: A report of two cases. J Neurosci Rural Pract; 2010 Jul;1(2):89-91
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  • The authors present a rare case of calcified (ossified) chronic epidural hematoma developed in a six-and-a-half-year-old female patient who was operated for cerebellar astrocytoma 6 months earlier.

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  • (PMID = 21808510.001).
  • [ISSN] 0976-3155
  • [Journal-full-title] Journal of neurosciences in rural practice
  • [ISO-abbreviation] J Neurosci Rural Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3139356
  • [Keywords] NOTNLM ; Epidural hematoma / calcified / pediatric epidural hematoma
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39. Baron PW, Majlessipour F, Bedros AA, Zuppan CW, Ben-Youssef R, Yanni G, Ojogho ON, Concepcion W: Undifferentiated embryonal sarcoma of the liver successfully treated with chemotherapy and liver resection. J Gastrointest Surg; 2007 Jan;11(1):73-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The first patient also had a concurrent cerebellar tumor (pilocytic astrocytoma), for which he first underwent craniotomy and resection, delaying the liver tumor resection by 10 weeks.

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  • (PMID = 17390190.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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40. Richter S, Schoch B, Kaiser O, Groetschel H, Dimitrova A, Hein-Kropp C, Maschke M, Gizewski ER, Timmann D: Behavioral and affective changes in children and adolescents with chronic cerebellar lesions. Neurosci Lett; 2005 Jun 10-17;381(1-2):102-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Behavioral and affective changes in children and adolescents with chronic cerebellar lesions.
  • The aim of the present study was to investigate if clinically relevant affective or behavioral changes as described in adults in the cerebellar affective syndrome by Schmahmann and Sherman [The cerebellar cognitive affective syndrome, Brain 121 (1998) 561-579] are likely to occur as a long-term sequelae of cerebellar vermis lesions in children.
  • Affect and behavior were assessed in children after cerebellar tumor surgery by means of experimenter ratings based on the description of the cerebellar affective syndrome and free ratings by the patients and their parents.
  • Twelve children and adolescents with a former cerebellar astrocytoma surgery without subsequent radiation or chemotherapy participated.
  • [MeSH-major] Cerebellar Diseases / complications. Cerebellar Diseases / diagnosis. Mental Disorders / diagnosis. Mental Disorders / etiology. Mood Disorders / diagnosis. Mood Disorders / etiology


91. MacKillop E, Thrall DE, Ranck RS, Linder KE, Munana KR: Imaging diagnosis--synchronous primary brain tumors in a dog. Vet Radiol Ultrasound; 2007 Nov-Dec;48(6):550-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Astrocytoma / veterinary. Cerebellar Neoplasms / veterinary. Dog Diseases / pathology. Medulloblastoma / veterinary. Neoplasms, Multiple Primary / veterinary. Thalamic Diseases / veterinary

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  • (PMID = 18018727.001).
  • [ISSN] 1058-8183
  • [Journal-full-title] Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
  • [ISO-abbreviation] Vet Radiol Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Kano T, Ikota H, Wada H, Iwasa S, Kurosaki S: A case of an anaplastic ependymoma with gliosarcomatous components. Brain Tumor Pathol; 2009;26(1):11-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Computed tomography revealed a large cystic lesion with a mural nodule-like mass homogeneously enhanced with contrast medium in the right cerebellum.
  • The tumor was removed, and pathological studies revealed a cerebellar astrocytoma corresponding to World Health Organization grade II.
  • When she was 35 years old, or 6 years after the surgery, magnetic resonance imaging revealed a recurrence of the tumor in the right cerebellum, and subtotal removal of the recurrent tumor was performed.
  • Thereafter, at 39 years of age, or 4 years after radiation therapy, magnetic resonance imaging again revealed a recurrence of the tumor, which was heterogeneously enhanced with gadoliniumdiethylenetriamine pentaacetic acid in the right cerebellum.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Ependymoma / pathology. Gliosarcoma / pathology
  • [MeSH-minor] Adult. Astrocytoma / pathology. Astrocytoma / surgery. Female. Glial Fibrillary Acidic Protein / metabolism. Headache / etiology. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Paraffin Embedding. Tomography, X-Ray Computed

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  • (PMID = 19408092.001).
  • [ISSN] 1861-387X
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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93. de Ribaupierre S, Ryser C, Villemure JG, Clarke S: Cerebellar lesions: is there a lateralisation effect on memory deficits? Acta Neurochir (Wien); 2008 Jun;150(6):545-50; discussion 550
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar lesions: is there a lateralisation effect on memory deficits?
  • BACKGROUND: Until recently, neurosurgeons eagerly removed cerebellar lesions without consideration of future cognitive impairment that might be caused by the resection.
  • In children, transient cerebellar mutism after resection has lead to a diminished use of midline approaches and vermis transection, as well as reduced retraction of the cerebellar hemispheres.
  • The role of the cerebellum in higher cognitive functions beyond coordination and motor control has recently attracted significant interest in the scientific community, and might change the neurosurgical approach to these lesions.
  • The aim of this study was to investigate the specific effects of cerebellar lesions on memory, and to assess a possible lateralisation effect.
  • METHODS: We studied 16 patients diagnosed with a cerebellar lesion, from January 1997 to April 2005, in the "Centre Hospitalier Universitaire Vaudois (CHUV)", Lausanne, Switzerland.
  • RESULTS: Severe memory deficits in at least one modality were identified in a majority (81%) of patients with cerebellar lesions.
  • FINDINGS: These findings are consistent with findings in the literature concerning memory deficits in isolated cerebellar lesions.
  • The high percentage of patients with a cerebellar lesion who demonstrate memory deficits should lead us to assess memory in all patients with cerebellar lesions.
  • [MeSH-major] Amnesia / physiopathology. Cerebellar Neoplasms / physiopathology. Dominance, Cerebral / physiology
  • [MeSH-minor] Adolescent. Adult. Aged. Amnesia, Anterograde / diagnosis. Amnesia, Anterograde / physiopathology. Astrocytoma / diagnosis. Astrocytoma / physiopathology. Astrocytoma / surgery. Cerebellum / physiopathology. Cerebellum / surgery. Female. Follow-Up Studies. Glioblastoma / diagnosis. Glioblastoma / physiopathology. Glioblastoma / surgery. Hemangioblastoma / diagnosis. Hemangioblastoma / physiopathology. Hemangioblastoma / surgery. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / physiopathology. Hemangioma, Cavernous / surgery. Humans. Male. Medulloblastoma / diagnosis. Medulloblastoma / physiopathology. Medulloblastoma / surgery. Memory, Short-Term / physiology. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / physiopathology. Meningeal Neoplasms / surgery. Meningioma / diagnosis. Meningioma / physiopathology. Meningioma / surgery. Middle Aged. Neuropsychological Tests. Postoperative Complications / diagnosis. Postoperative Complications / physiopathology. Verbal Learning / physiology

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  • (PMID = 18512000.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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94. Mezer E, Nischal KK, Nahjawan N, MacKeen LD, Buncic JR: Hemifacial spasm as the initial manifestation of childhood cerebellar astrocytoma. J AAPOS; 2006 Oct;10(5):489-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemifacial spasm as the initial manifestation of childhood cerebellar astrocytoma.

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  • (PMID = 17070492.001).
  • [ISSN] 1091-8531
  • [Journal-full-title] Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • [ISO-abbreviation] J AAPOS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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95. Demir MK, Hakan T, Akinci O, Berkman Z: Primary cerebellar glioblastoma multiforme. Diagn Interv Radiol; 2005 Jun;11(2):83-6
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  • [Title] Primary cerebellar glioblastoma multiforme.
  • Primary glioblastoma multiforme of cerebellar hemispheres in adults is a rare condition.
  • Most of them result from dedifferentiation of astrocytoma to glioblastoma.
  • We present two cases of unusual de novo cerebellar glioblastomas, one of which is the giant-cell variant.
  • [MeSH-major] Cerebellar Neoplasms / radiography. Glioblastoma / radiography

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  • (PMID = 15957093.001).
  • [ISSN] 1305-3825
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
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96. Schiff D: Brain tumor patients with uncertain metastatic potential as organ donors in infancy and childhood. Klin Padiatr; 2010 May;222(3):197; author reply 198
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Astrocytoma / pathology. Astrocytoma / secondary. Astrocytoma / surgery. Blood-Brain Barrier / physiology. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Child. Child, Preschool. Craniotomy / contraindications. Humans. Infant. Medulloblastoma / pathology. Medulloblastoma / secondary. Medulloblastoma / surgery. Neuroectodermal Tumors, Primitive / pathology. Neuroectodermal Tumors, Primitive / secondary. Neuroectodermal Tumors, Primitive / surgery. Risk Factors. Ventriculoperitoneal Shunt / contraindications


97. Huo L, Bi C, Fang J, Wang Y, Zhang M, Chen F: [Microsurgical treatment and prevention of postoperative complications for the fourth ventricle tumors in adults]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2009 Jul;34(7):642-5
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  • Tumors were excised by inferior vermis cerebellar approach or cerebellomedullary fissure approach.
  • [MeSH-major] Astrocytoma / surgery. Cerebral Ventricle Neoplasms / surgery. Fourth Ventricle / surgery. Microsurgery / methods. Postoperative Complications / prevention & control

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  • (PMID = 19648678.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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98. Manley S, Crooks D, Artingstall L, Buxton N, Appleton R, Riordan A, Cleary G, Pizer B: Diffuse central nervous system protoplasmic astrocytoma. Pediatr Blood Cancer; 2010 May;54(5):768-9
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  • [Title] Diffuse central nervous system protoplasmic astrocytoma.
  • Protoplasmic astrocytoma is an extremely rare form of grade II low grade glioma which usually presents as a discrete mass lesion.
  • We describe a 3-year-old female with diffuse protoplasmic astrocytoma with parenchymal involvement and leptomeningeal spread.
  • Three superficial biopsies did not give the diagnosis and this was only confirmed 8 months from presentation from a larger fourth biopsy taken deeper from the cerebellum.
  • To our knowledge this case represents the distinct presentation of protoplasmic astrocytoma presenting as extensive diffuse meningeal disease.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Meningeal Neoplasms / pathology

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  • (PMID = 20049933.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Agir H, Sen C, Muezzinoglu B, Isl E: Report of a radiation-induced leiomyosarcoma arising from the posterior neck. J Craniofac Surg; 2007 Sep;18(5):1018-20
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  • Herein, we report a 48-year-old male patient who developed leiomyosarcoma in his posterior neck region, which was previously radiated due to a cerebellar astrocytoma.
  • [MeSH-minor] Astrocytoma / radiotherapy. Cerebellar Neoplasms / radiotherapy. Humans. Male. Middle Aged

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  • (PMID = 17912075.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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100. Hoffman S, Schellinger KA, Propp JM, McCarthy BJ, Campbell RT, Davis FG: Seasonal variation in incidence of pediatric medulloblastoma in the United States, 1995-2001. Neuroepidemiology; 2007;29(1-2):89-95
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  • There were no significant results for brain tumors overall, or for the other most common pediatric tumor subtypes (pilocytic astrocytoma, other astrocytoma, and ependymoma).
  • [MeSH-major] Cerebellar Neoplasms / epidemiology. Medulloblastoma / epidemiology. Parturition. Seasons

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  • [Copyright] (c) 2007 S. Karger AG, Basel.
  • (PMID = 17925600.001).
  • [ISSN] 1423-0208
  • [Journal-full-title] Neuroepidemiology
  • [ISO-abbreviation] Neuroepidemiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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