[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 32 of about 32
1. Krueger DA, Care MM, Holland K, Agricola K, Tudor C, Mangeshkar P, Wilson KA, Byars A, Sahmoud T, Franz DN: Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. N Engl J Med; 2010 Nov 4;363(19):1801-11
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.
  • BACKGROUND: Neurosurgical resection is the standard treatment for subependymal giant-cell astrocytomas in patients with the tuberous sclerosis complex.
  • METHODS: Patients 3 years of age or older with serial growth of subependymal giant-cell astrocytomas were eligible for this open-label study.
  • The primary efficacy end point was the change in volume of subependymal giant-cell astrocytomas between baseline and 6 months.
  • Everolimus therapy was associated with a clinically meaningful reduction in volume of the primary subependymal giant-cell astrocytoma, as assessed on independent central review (P<0.001 for baseline vs. 6 months), with a reduction of at least 30% in 21 patients (75%) and at least 50% in 9 patients (32%).
  • There were no new lesions, worsening hydrocephalus, evidence of increased intracranial pressure, or necessity for surgical resection or other therapy for subependymal giant-cell astrocytoma.
  • CONCLUSIONS: Everolimus therapy was associated with marked reduction in the volume of subependymal giant-cell astrocytomas and seizure frequency and may be a potential alternative to neurosurgical resection in some cases, though long-term studies are needed. (Funded by Novartis; ClinicalTrials.gov number, NCT00411619.).
  • [MeSH-major] Astrocytoma / drug therapy. Brain Neoplasms / drug therapy. Intracellular Signaling Peptides and Proteins / antagonists & inhibitors. Protein-Serine-Threonine Kinases / antagonists & inhibitors. Seizures / drug therapy. Sirolimus / analogs & derivatives. Tuberous Sclerosis / drug therapy
  • [MeSH-minor] Administration, Oral. Adolescent. Adult. Angiofibroma / drug therapy. Anticonvulsants / therapeutic use. Child. Child, Preschool. Cognition / drug effects. Drug Therapy, Combination. Everolimus. Facial Neoplasms / drug therapy. Female. Humans. Male. Prospective Studies. Quality of Life. TOR Serine-Threonine Kinases. Young Adult


2. Koenig MK, Butler IJ, Northrup H: Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex. J Child Neurol; 2008 Oct;23(10):1238-9
Hazardous Substances Data Bank. SIROLIMUS .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex.
  • The authors present a 21-year-old woman who has been receiving rapamycin for 5 months for bilateral subependymal giant cell astrocytomas.
  • Magnetic resonance imaging of the brain 2(1/2) months after initiating rapamycin demonstrated a decrease in size of both astrocytomas (11 to 7.5 mm on the right and 8 to 5 mm on the left).

  • Genetic Alliance. consumer health - Subependymal giant cell astrocytoma.
  • Genetic Alliance. consumer health - Tuberous sclerosis.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Tuberous Sclerosis.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Pediatr Res. 2005 Jan;57(1):67-75 [15557109.001]
  • [Cites] BMC Dermatol. 2008;8:1 [18226258.001]
  • [Cites] N Engl J Med. 2008 Jan 10;358(2):140-51 [18184959.001]
  • [Cites] Ann Neurol. 2006 Mar;59(3):490-8 [16453317.001]
  • (PMID = 18952591.001).
  • [ISSN] 1708-8283
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / KL2 RR024149; United States / NCRR NIH HHS / RR / RR024149-05S1; United States / NCRR NIH HHS / RR / KL2 RR024149-05S1
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; W36ZG6FT64 / Sirolimus
  • [Other-IDs] NLM/ NIHMS282750; NLM/ PMC3072698
  •  go-up   go-down


3. Pascual-Castroviejo I, Pascual-Pascual SI, Velázquez-Fragua R, Viaño J, Carceller F, Hernández-Moneo JL, Gutiérrez-Molina M, Morales C: [Subependymal giant cell astrocytoma in tuberous sclerosis complex. A presentation of eight paediatric patients]. Neurologia; 2010 Jun;25(5):314-21
MedlinePlus Health Information. consumer health - Tuberous Sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Subependymal giant cell astrocytoma in tuberous sclerosis complex. A presentation of eight paediatric patients].
  • [Transliterated title] Astrocitoma subependimario de células gigantes en el complejo de esclerosis tuberosa. Presentación de ocho pacientes infantiles.
  • OBJECTIVE: Presentation of 8 patients with subependymal giant-cell astrocytomas (SGCA) associated with tuberous sclerosis complex (TSC).
  • Only one patient developed the tumour suddenly from pre-existing subependymal nodules from the childhood and they had to be removed at 24 years of age.
  • By contrast, 32 patients with TSC and images of subependymal nodules whose CT or MR progress was followed up for between 10 and 30 years did not develop a tumour.
  • [MeSH-major] Astrocytoma / etiology. Astrocytoma / pathology. Brain Neoplasms / etiology. Brain Neoplasms / pathology. Tuberous Sclerosis
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Magnetic Resonance Imaging. Male. Retrospective Studies. Tomography, X-Ray Computed. Young Adult


Advertisement
4. Kim SH, Lee KG, Kim TS: Cytologic characteristics of subependymal giant cell astrocytoma in squash smears: morphometric comparisons with gemistocytic astrocytoma and giant cell glioblastoma. Acta Cytol; 2007 May-Jun;51(3):375-9
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytologic characteristics of subependymal giant cell astrocytoma in squash smears: morphometric comparisons with gemistocytic astrocytoma and giant cell glioblastoma.
  • OBJECTIVE: To evaluate the squash smear features of subependymal giant cell astrocytoma (SEGA) in comparison with gemistocytic astrocytoma and giant cell glioblastoma.
  • STUDY DESIGN: We compared the squash smear features of 3 cases of SEGA, 9 cases of gemistocytic astrocytoma and 3 cases of giant cell glioblastoma with the morphometric findings.
  • While the gemistocytic astrocytoma had several tumor cells showing a vertically located nucleus, the tumor cells of SEGA showed nuclei oriented mainly in parallel.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Glioblastoma / pathology
  • [MeSH-minor] Adolescent. Adult. Cell Nucleus / pathology. Child. Child, Preschool. Cytoplasm / pathology. Diagnosis, Differential. Female. Humans. Male


5. Takata K, Gasparetto EL, Leite Cda C, Lucato LT, Reed UC, Matushita H, Aguiar PH, Rosemberg S: [Subependymal giant cell astrocytoma in patients with tuberous sclerosis: magnetic resonance imaging findings in ten cases]. Arq Neuropsiquiatr; 2007 Jun;65(2A):313-6
MedlinePlus Health Information. consumer health - Tuberous Sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Subependymal giant cell astrocytoma in patients with tuberous sclerosis: magnetic resonance imaging findings in ten cases].
  • [Transliterated title] Astrocitoma subependimário de células gigantes em pacientes com esclerose tuberosa: achados em ressonância magnética de dez casos.
  • OBJECTIVE: To report the magnetic resonance imaging (MRI) findings in 10 patients with subependimal giant cell astrocytoma (SGCA) and tuberous sclerosis (TS).
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Ventricles / pathology. Tuberous Sclerosis / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Contrast Media. Female. Humans. Image Enhancement. Magnetic Resonance Imaging / standards. Male. Retrospective Studies. Tomography, X-Ray Computed


6. Pollock JM, Whitlow CT, Tan H, Kraft RA, Burdette JH, Maldjian JA: Pulsed arterial spin-labeled MR imaging evaluation of tuberous sclerosis. AJNR Am J Neuroradiol; 2009 Apr;30(4):815-20
MedlinePlus Health Information. consumer health - Tuberous Sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND AND PURPOSE: Tuberous sclerosis presents with characteristic cortical hamartomas and subependymal nodules associated with seizures.
  • One patient had a subependymal giant cell astrocytoma with a mean perfusion of 93.5 mL/100 g tissue/min.
  • [MeSH-minor] Adolescent. Astrocytoma / etiology. Astrocytoma / pathology. Brain Diseases / complications. Brain Diseases / pathology. Brain Neoplasms / etiology. Brain Neoplasms / pathology. Child. Child, Preschool. Disease Progression. Hamartoma / complications. Hamartoma / pathology. Humans. Infant. Retrospective Studies. Young Adult

  • Genetic Alliance. consumer health - Tuberous sclerosis.
  • MedlinePlus Health Information. consumer health - Epilepsy.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19147711.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Grant] United States / NIBIB NIH HHS / EB / EB004673
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Spin Labels
  •  go-up   go-down


7. Ichikawa T, Wakisaka A, Daido S, Takao S, Tamiya T, Date I, Koizumi S, Niida Y: A case of solitary subependymal giant cell astrocytoma: two somatic hits of TSC2 in the tumor, without evidence of somatic mosaicism. J Mol Diagn; 2005 Oct;7(4):544-9
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of solitary subependymal giant cell astrocytoma: two somatic hits of TSC2 in the tumor, without evidence of somatic mosaicism.
  • Subependymal giant cell astrocytoma (SEGA) is a unique brain tumor arising in tuberous sclerosis complex (TSC), an autosomal dominant inherited phacomatosis.
  • [MeSH-major] Astrocytoma / genetics. Astrocytoma / pathology. Brain Neoplasms / genetics. Brain Neoplasms / pathology. Mosaicism. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adult. Base Sequence. Female. Humans. Loss of Heterozygosity. Magnetic Resonance Imaging. Mutation / genetics

  • Genetic Alliance. consumer health - Subependymal giant cell astrocytoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Hum Genet. 1996 Aug;59(2):400-6 [8755927.001]
  • [Cites] Am J Hum Genet. 1999 Jun;64(6):1632-7 [10330349.001]
  • [Cites] Cancer Res. 1997 Mar 15;57(6):1188-93 [9067291.001]
  • [Cites] Science. 1997 Aug 8;277(5327):805-8 [9242607.001]
  • [Cites] Am J Hum Genet. 1998 Apr;62(4):810-5 [9529362.001]
  • [Cites] Hum Mutat. 1998;12(6):408-16 [9829910.001]
  • [Cites] J Child Neurol. 1998 Dec;13(12):624-8 [9881533.001]
  • [Cites] N Engl J Med. 1999 Mar 4;340(9):703-7 [10053179.001]
  • [Cites] Hum Mutat. 1999;14(5):412-22 [10533067.001]
  • [Cites] J Med Genet. 2000 Jan;37(1):55-7 [10633137.001]
  • [Cites] Eur J Radiol. 2000 Jan;33(1):55-8 [10674791.001]
  • [Cites] Neurogenetics. 1998 Aug;1(4):267-72 [10732801.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 May 23;97(11):6085-90 [10823953.001]
  • [Cites] J Am Acad Dermatol. 2000 Jul;43(1 Pt 1):127-9 [10863238.001]
  • [Cites] Am J Hum Genet. 2001 Sep;69(3):493-503 [11468687.001]
  • [Cites] Pediatr Neurosurg. 2002 May;36(5):271-4 [12053047.001]
  • [Cites] Neurol Med Chir (Tokyo). 2002 May;42(5):224-7 [12064158.001]
  • [Cites] Neurol Med Chir (Tokyo). 2003 Dec;43(12):616-8 [14723270.001]
  • [Cites] Cancer Res. 2004 Feb 1;64(3):812-6 [14871804.001]
  • [Cites] J Neurosurg. 1979 Jan;50(1):106-9 [758371.001]
  • [Cites] Childs Nerv Syst. 1989 Feb;5(1):43-4 [2702677.001]
  • [Cites] Neurosurgery. 1991 Jun;28(6):864-8 [2067610.001]
  • [Cites] J Child Neurol. 1992 Apr;7(2):221-4 [1573244.001]
  • [Cites] Cell. 1993 Dec 31;75(7):1305-15 [8269512.001]
  • [Cites] Am J Forensic Med Pathol. 1995 Mar;16(1):30-7 [7771379.001]
  • [Cites] Am J Hum Genet. 1999 Apr;64(4):986-92 [10090883.001]
  • [Cites] Am J Hum Genet. 1999 May;64(5):1305-15 [10205261.001]
  • [Cites] Hum Mol Genet. 1996 Feb;5(2):215-21 [8824877.001]
  • (PMID = 16237225.001).
  • [ISSN] 1525-1578
  • [Journal-full-title] The Journal of molecular diagnostics : JMD
  • [ISO-abbreviation] J Mol Diagn
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; 4JG2LF96VF / tuberous sclerosis complex 2 protein
  • [Other-IDs] NLM/ PMC1888498
  •  go-up   go-down


8. Stavrinou P, Spiliotopoulos A, Patsalas I, Balogiannis I, Karkavelas G, Polyzoidis K, Selviaridis P: Subependymal giant cell astrocytoma with intratumoral hemorrhage in the absence of tuberous sclerosis. J Clin Neurosci; 2008 Jun;15(6):704-6
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subependymal giant cell astrocytoma with intratumoral hemorrhage in the absence of tuberous sclerosis.
  • Subependymal giant cell astrocytoma (SEGA) is an uncommon tumor that usually occurs in the setting of tuberous sclerosis (TS) syndrome.
  • We report a rare case of an intratumoral and a small intraventricular hemorrhage complicating a SEGA in an adult patient without any signs of TS.
  • This is the second report of intraventricular and intratumoral hemorrhage complicating a SEGA and the first case in which these complications occurred in an adult patient in whom there was no previous suspicion of systemic disease.
  • [MeSH-major] Astrocytoma / complications. Brain Neoplasms / complications. Hemorrhage / etiology
  • [MeSH-minor] Adult. Glial Fibrillary Acidic Protein / metabolism. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed / methods

  • Genetic Alliance. consumer health - Subependymal giant cell astrocytoma.
  • Genetic Alliance. consumer health - Tuberous sclerosis.
  • MedlinePlus Health Information. consumer health - Bleeding.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18395450.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
  •  go-up   go-down


9. Ibrahim I, Young CA, Larner AJ: Fornix damage from solitary subependymal giant cell astrocytoma causing postoperative amnesic syndrome. Br J Hosp Med (Lond); 2009 Aug;70(8):478-9
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fornix damage from solitary subependymal giant cell astrocytoma causing postoperative amnesic syndrome.
  • This article reports the cognitive impairments associated with left fornix damage which became apparent following surgical removal of a solitary subependymal giant cell astrocytoma.
  • [MeSH-major] Amnesia / etiology. Astrocytoma / complications. Fornix, Brain. Postoperative Complications / etiology
  • [MeSH-minor] Female. Humans. Syndrome. Tomography, X-Ray Computed. Young Adult

  • Genetic Alliance. consumer health - Subependymal giant cell astrocytoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19684542.001).
  • [ISSN] 1750-8460
  • [Journal-full-title] British journal of hospital medicine (London, England : 2005)
  • [ISO-abbreviation] Br J Hosp Med (Lond)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


10. Chen H, Sun XF, Wu JS: [Clinicopathologic study of subependymal giant cell astrocytoma]. Zhonghua Bing Li Xue Za Zhi; 2006 Nov;35(11):656-9
Genetic Alliance. consumer health - Subependymal giant cell astrocytoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinicopathologic study of subependymal giant cell astrocytoma].
  • OBJECTIVE: To study the clinicopathologic features of subependymal giant cell astrocytoma.
  • METHODS: The clinical and pathologic characteristics of 18 cases of subependymal giant cell astrocytoma were retrospectively analyzed.
  • CONCLUSIONS: Subependymal giant cell astrocytoma is a benign brain tumor with distinctive histopathologic features.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Female. Follow-Up Studies. Glial Fibrillary Acidic Protein / biosynthesis. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Synaptophysin / biosynthesis. Tomography, X-Ray Computed. Tuberous Sclerosis / complications. Tuberous Sclerosis / metabolism. Tuberous Sclerosis / pathology. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17374208.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Synaptophysin
  •  go-up   go-down


11. Raju GP, Urion DK, Sahin M: Neonatal subependymal giant cell astrocytoma: new case and review of literature. Pediatr Neurol; 2007 Feb;36(2):128-31
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neonatal subependymal giant cell astrocytoma: new case and review of literature.
  • Subependymal giant cell astrocytomas are one of the three major intracranial lesions found in tuberous sclerosis complex.
  • Subependymal giant cell astrocytomas are typically slow-growing tumors of mixed glioneuronal lineage which can become aggressive and cause obstructive hydrocephalus usually in older children and adolescents.
  • Neonatal subependymal giant cell astrocytomas are extremely rare, and their natural history and prognosis are poorly understood.
  • This report investigates an extremely large neonatal subependymal giant cell astrocytoma which was initially identified in utero at 19 weeks of gestation in a high-risk pregnancy with no family history of tuberous sclerosis complex.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Magnetic Resonance Imaging
  • [MeSH-minor] Adult. Fatal Outcome. Female. Humans. Infant, Newborn. Pregnancy. Pregnancy, High-Risk. Prenatal Diagnosis. Tuberous Sclerosis

  • Genetic Alliance. consumer health - Subependymal giant cell astrocytoma.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17275668.001).
  • [ISSN] 0887-8994
  • [Journal-full-title] Pediatric neurology
  • [ISO-abbreviation] Pediatr. Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 16
  •  go-up   go-down


12. Cai R, Di X: Combined intra- and extra-endoscopic techniques for aggressive resection of subependymal giant cell astrocytomas. World Neurosurg; 2010 Jun;73(6):713-8
MedlinePlus Health Information. consumer health - Endoscopy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combined intra- and extra-endoscopic techniques for aggressive resection of subependymal giant cell astrocytomas.
  • We report two cases of combined intra-/extra-axial endoscopic procedures--intraventricular solid tumor resection for subependymal giant cell astrocytoma.
  • METHODS: In 2007, two patients with subependymal giant cell astrocytoma with a long history of tuberous sclerosis underwent solely endoscopic, minimally invasive intraventricular tumor resection.
  • Pathologic diagnoses were subependymal giant cell astrocytoma.
  • EMIN is a completive, safe procedure for intraventricular subependymal giant cell astrocytoma.
  • [MeSH-major] Astrocytoma / surgery. Cerebral Ventricle Neoplasms / surgery. Endoscopy / methods. Frontal Lobe / surgery. Lateral Ventricles / surgery. Neurosurgical Procedures / methods
  • [MeSH-minor] Adolescent. Combined Modality Therapy / instrumentation. Combined Modality Therapy / methods. Female. Humans. Male. Microsurgery / methods. Minimally Invasive Surgical Procedures / instrumentation. Minimally Invasive Surgical Procedures / methods. Treatment Outcome. Tuberous Sclerosis / complications. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20934162.001).
  • [ISSN] 1878-8769
  • [Journal-full-title] World neurosurgery
  • [ISO-abbreviation] World Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


13. Adriaensen ME, Schaefer-Prokop CM, Stijnen T, Duyndam DA, Zonnenberg BA, Prokop M: Prevalence of subependymal giant cell tumors in patients with tuberous sclerosis and a review of the literature. Eur J Neurol; 2009 Jun;16(6):691-6
MedlinePlus Health Information. consumer health - Tuberous Sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prevalence of subependymal giant cell tumors in patients with tuberous sclerosis and a review of the literature.
  • BACKGROUND AND PURPOSE: To investigate the prevalence of subependymal giant cell ependymomas (SEGA) in patients with tuberous sclerosis complex (TSC).
  • [MeSH-major] Astrocytoma / epidemiology. Brain Neoplasms / epidemiology. Tuberous Sclerosis / epidemiology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Brain / pathology. Brain / physiopathology. Brain / radiography. Cerebral Aqueduct / pathology. Cerebral Aqueduct / physiopathology. Cerebral Aqueduct / radiography. Child. Cohort Studies. Comorbidity. Cross-Sectional Studies. Female. Humans. Hydrocephalus / epidemiology. Male. Middle Aged. Netherlands / epidemiology. Predictive Value of Tests. Prevalence. Retrospective Studies. Tomography, X-Ray Computed. Young Adult


14. O'Callaghan FJ, Martyn CN, Renowden S, Noakes M, Presdee D, Osborne JP: Subependymal nodules, giant cell astrocytomas and the tuberous sclerosis complex: a population-based study. Arch Dis Child; 2008 Sep;93(9):751-4
MedlinePlus Health Information. consumer health - Tuberous Sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subependymal nodules, giant cell astrocytomas and the tuberous sclerosis complex: a population-based study.
  • OBJECTIVES:. (1) In a population-based study of tuberous sclerosis (TSC), to identify the number of patients presenting with symptomatic giant cell astrocytomas (GCAs);.
  • Thirty-nine of these had subependymal nodules, of whom 24 (59%) had at least one (maximum 11) that showed enhancement with gadolinium.
  • [MeSH-major] Astrocytoma / epidemiology. Brain Neoplasms / epidemiology. Tuberous Sclerosis / epidemiology
  • [MeSH-minor] Adolescent. Adult. Child. Cross-Sectional Studies. Female. Humans. Intracranial Hypertension / etiology. Intracranial Hypertension / surgery. Magnetic Resonance Imaging. Male. Mental Disorders / etiology. Tomography, X-Ray Computed. Tumor Suppressor Proteins / metabolism

  • Genetic Alliance. consumer health - Tuberous sclerosis.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Arch Dis Child. 2009 Jan;94(1):75-6 [19103791.001]
  • (PMID = 18456692.001).
  • [ISSN] 1468-2044
  • [Journal-full-title] Archives of disease in childhood
  • [ISO-abbreviation] Arch. Dis. Child.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins
  •  go-up   go-down


15. Ellert-Miklaszewska A, Grajkowska W, Gabrusiewicz K, Kaminska B, Konarska L: Distinctive pattern of cannabinoid receptor type II (CB2) expression in adult and pediatric brain tumors. Brain Res; 2007 Mar 16;1137(1):161-9
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distinctive pattern of cannabinoid receptor type II (CB2) expression in adult and pediatric brain tumors.
  • Although brain tumors constitute the second most common malignancy in children and the prevalence of histological types of brain tumors vary significantly between the adult and pediatric populations, cannabinoid receptor expression in pediatric tumors remains unknown.
  • In the present study, we compared the expression of the CB2 receptor in paraffin-embedded sections from primary brain tumors of adult and pediatric patients.
  • Interestingly, some benign pediatric astrocytic tumors, such as subependymal giant cell astrocytoma (SEGA), which may occasionally cause mortality owing to progressive growth, also displayed high CB2 immunoreactivity.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Astrocytoma / metabolism. Child. Glioblastoma / metabolism. Histocompatibility Antigens / metabolism. Humans. Immunohistochemistry. Reverse Transcriptase Polymerase Chain Reaction / methods

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17239827.001).
  • [ISSN] 0006-8993
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Histocompatibility Antigens; 0 / Receptor, Cannabinoid, CB2
  •  go-up   go-down


16. Kawaguchi T, Kumabe T, Shimizu H, Watanabe M, Tominaga T: 201Tl-SPECT and 1H-MRS study of benign lateral ventricle tumors: differential diagnosis of subependymoma. Neurosurg Rev; 2005 Apr;28(2):96-103
Genetic Alliance. consumer health - Subependymoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 201Tl-SPECT and 1H-MRS study of benign lateral ventricle tumors: differential diagnosis of subependymoma.
  • Our study includes nine cases of benign lateral ventricle tumors including two cases of central neurocytoma, two of subependymal giant cell astrocytoma, two of pilocytic astrocytoma and three of subependymoma treated surgically between 1996 and 2003.
  • All three types of tumor demonstrated heterogeneous enhancement on MR imaging with gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) and increased choline (Cho) peak and decreased N-acetyl aspartate (NAA) and creatine (Cre) peaks on (1)H-MRS. (201)Tl-SPECT showed high uptake of (201)Tl without wash out in all cases of central neurocytoma, subependymal giant cell astrocytoma and pilocytic astrocytoma, but no uptake in cases of subependymoma.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebral Ventricle Neoplasms / diagnosis. Glioma, Subependymal / diagnosis. Lateral Ventricles. Neurocytoma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Diagnosis, Differential. Female. Humans. Magnetic Resonance Spectroscopy. Male. Middle Aged. Retrospective Studies. Thallium Radioisotopes. Tomography, Emission-Computed, Single-Photon

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Nucl Med. 1998 Jun;12 (3):161-4 [9673719.001]
  • [Cites] NMR Biomed. 1989 Dec;2(5-6):196-200 [2561957.001]
  • [Cites] Radiology. 1984 Nov;153(2):435-42 [6333046.001]
  • [Cites] Radiology. 1982 Apr;143(1):97-101 [7063750.001]
  • [Cites] Br J Radiol. 1983 Jun;56(666):425-6 [6850230.001]
  • [Cites] AJR Am J Roentgenol. 1990 Aug;155(2):365-72 [2115270.001]
  • [Cites] AJR Am J Roentgenol. 1995 Nov;165(5):1245-50 [7572512.001]
  • [Cites] J Comput Assist Tomogr. 1995 Mar-Apr;19(2):264-7 [7890853.001]
  • [Cites] Neuroradiology. 1993;35(3):185-6 [8459915.001]
  • [Cites] Oncol Rep. 1998 Sep-Oct;5(5):1199-203 [9683835.001]
  • [Cites] Eur J Nucl Med. 1993 Feb;20(2):138-45 [8440270.001]
  • [Cites] AJNR Am J Neuroradiol. 1996 Apr;17(4):737-47 [8730195.001]
  • [Cites] J Magn Reson Imaging. 2003 Feb;17(2):256-60 [12541233.001]
  • [Cites] Neurosurgery. 1999 Jul;45(1):183-7; discussion 187 [10414585.001]
  • [Cites] Surg Neurol. 1990 May;33(5):329-35 [2330534.001]
  • [Cites] Int J Oncol. 1997 Aug;11(2):319-24 [21528217.001]
  • [Cites] J Neurosurg. 1991 Oct;75(4):583-8 [1885976.001]
  • [Cites] Kaku Igaku. 2000 Jul;37(4):311-8 [10965651.001]
  • [Cites] Neurol Med Chir (Tokyo). 2001 Sep;41(9):431-4; discussion 435 [11593969.001]
  • [Cites] AJNR Am J Neuroradiol. 1990 Jan-Feb;11(1):83-91 [2105621.001]
  • [Cites] Radiology. 2004 Mar;230(3):703-8 [14739313.001]
  • [Cites] Neuroradiology. 1983;25(1):11-22 [6856076.001]
  • [Cites] Neurosurgery. 2000 Feb;46(2):329-33; discussion 333-4 [10690721.001]
  • [Cites] J Neurooncol. 2003 Jan;61(1):57-67 [12587796.001]
  • [Cites] Br J Radiol. 1980 May;53(629):443-53 [7388277.001]
  • [Cites] Acta Neurochir (Wien). 2002 Feb;144(2):157-63; discussion 163 [11862516.001]
  • [Cites] AJNR Am J Neuroradiol. 1995 Sep;16(8):1593-603 [7502961.001]
  • [Cites] J Comput Assist Tomogr. 1994 Jan-Feb;18(1):129-30 [8282862.001]
  • [Cites] Neurosurgery. 1986 Oct;19(4):594-8 [3785597.001]
  • [Cites] Clin Neurol Neurosurg. 1997 Feb;99(1):17-22 [9107462.001]
  • [Cites] Neuroradiology. 1998 Apr;40(4):210-5 [9592789.001]
  • [Cites] J Nucl Med. 1995 Apr;36(4):537-41 [7699438.001]
  • [Cites] AJNR Am J Neuroradiol. 2000 Apr;21(4):659-65 [10782774.001]
  • [Cites] Radiology. 1978 Aug;128(2):417-22 [663252.001]
  • [Cites] Neuroradiology. 1984;26(3):223-8 [6738854.001]
  • (PMID = 15580370.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Thallium Radioisotopes
  •  go-up   go-down


17. White JB, Miller GM, Layton KF, Krauss WE: Nonenhancing tumors of the spinal cord. J Neurosurg Spine; 2007 Oct;7(4):403-7
Hazardous Substances Data Bank. GADOPENTETATE DIMEGLUMINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histologically, a majority of tumors were astrocytomas (eight low-grade and two high-grade lesions); one tumor was a subependymoma.
  • [MeSH-major] Astrocytoma / pathology. Astrocytoma / radiography. Glioma, Subependymal / pathology. Glioma, Subependymal / radiography. Spinal Cord Neoplasms / pathology. Spinal Cord Neoplasms / radiography
  • [MeSH-minor] Adult. Aged. Child. Child, Preschool. Contrast Media. Female. Gadolinium DTPA. Humans. Image Enhancement. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17933314.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
  •  go-up   go-down


18. Kidd EA, Mansur DB, Leonard JR, Michalski JM, Simpson JR, Perry A: The efficacy of radiation therapy in the management of grade I astrocytomas. J Neurooncol; 2006 Jan;76(1):55-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The efficacy of radiation therapy in the management of grade I astrocytomas.
  • INTRODUCTION: The purpose of this study was to analyze the outcome of patients with grade I astrocytomas treated with radiation therapy, specifically looking at the prognostic significance of age, timing of radiation therapy (immediately after surgery or delayed until progression) and tumor location.
  • MATERIALS AND METHODS: The records of patients with grade I astrocytomas treated at Washington University Medical Center between 1982 and 2002 were reviewed.
  • Twenty patients with grade I pilocytic astrocytoma (n=19) or subependymal giant cell astrocytoma (n=1) were treated with radiation therapy with curative intent.
  • CONCLUSIONS: While this study reports an excellent overall survival, approximately one third of patients with grade I astrocytomas had progressive disease following radiation therapy.
  • [MeSH-major] Astrocytoma / radiotherapy. Brain Neoplasms / radiotherapy. Neoplasm Recurrence, Local
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Male. Prognosis. Retrospective Studies. Survival Analysis. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16132503.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


19. Murai N, Kaneko T: [Case of jugular foramen schwannoma associated with tuberous sclerosis]. No Shinkei Geka; 2007 Oct;35(10):1007-11
MedlinePlus Health Information. consumer health - Tuberous Sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Her tuberous sclerosis was diagnosed at the age of 9, when she developed hydrocephalus caused by subependymal giant cell astrocytoma near the foramen of Monro, which was treated by surgical resection and VP shunt placement followed by radiation and chemotherapy.
  • [MeSH-minor] Adult. Astrocytoma / etiology. Astrocytoma / therapy. Cerebral Ventricle Neoplasms / etiology. Cerebral Ventricle Neoplasms / therapy. Cerebral Ventricles. Female. Humans. Hydrocephalus / etiology. Treatment Outcome

  • Genetic Alliance. consumer health - Schwannoma.
  • Genetic Alliance. consumer health - Tuberous sclerosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17969337.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


20. Timotin L, Sarrot-Reynauld F, Lantuejoul S, Pasquier B, Massot C, Ashraf A, Borgel F: [Tuberous sclerosis without mental impairment, diagnosed in adulthood]. Rev Med Interne; 2005 Jun;26(6):511-3
MedlinePlus Health Information. consumer health - Tuberous Sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Sclérose tubéreuse de Bourneville sans altération intellectuelle, diagnostiquée à l'âge adulte.
  • EXEGESIS: We report a case of TSC diagnosed in a 33-year-old man, without any known family history of phakomatosis, presenting with facial angiofibromas, hypomelanotic macules, a giant-cell astrocytoma and retinal phakomas without any mental impairment or epilepsy.
  • CONCLUSION: TSC may occur in patients who do not have any family history of phakomatosis because de novo mutations are frequent.
  • They should lead to brain imaging in search for astrocytoma, subependymal nodules and cortical tubers which number is directly correlated with the risk of seizures and the degree of mental impairment.

  • Genetic Alliance. consumer health - Tuberous sclerosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15936480.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


21. Henderson MA, Fakiris AJ, Timmerman RD, Worth RM, Lo SS, Witt TC: Gamma knife stereotactic radiosurgery for low-grade astrocytomas. Stereotact Funct Neurosurg; 2009;87(3):161-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gamma knife stereotactic radiosurgery for low-grade astrocytomas.
  • Patients with low-grade astrocytoma (LGA; 8 pilocytic astrocytomas, 2 subependymal giant cell astrocytomas, 2 fibrillary astrocytomas) were selected for treatment with gamma knife stereotactic radiosurgery (GKSRS) based on having a demarcated appearance on CT or MRI and the possibility of dose sparing of adjacent eloquent structures.
  • [MeSH-major] Astrocytoma / surgery. Brain Neoplasms / surgery. Radiosurgery / methods
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Survival Rate / trends. Young Adult

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2009 S. Karger AG, Basel.
  • (PMID = 19321969.001).
  • [ISSN] 1423-0372
  • [Journal-full-title] Stereotactic and functional neurosurgery
  • [ISO-abbreviation] Stereotact Funct Neurosurg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  •  go-up   go-down


22. Schittenhelm J, Trautmann K, Tabatabai G, Hermann C, Meyermann R, Beschorner R: Comparative analysis of annexin-1 in neuroepithelial tumors shows altered expression with the grade of malignancy but is not associated with survival. Mod Pathol; 2009 Dec;22(12):1600-11
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the normal human brain, the expression of annexin-1 is limited to ependymal cells and subependymal astrocytes, but is also upregulated in reactive astrocytes.
  • Ependymomas and astrocytomas showed significantly higher mean annexin-1 expression levels in the cytoplasm compared with oligodendrogliomas (both: P<0.0001).
  • In addition, nuclear staining of annexin-1 in oligodendroglial tumor cells was significantly reduced (P=0.0002), which may be used as a diagnostic tool for differentiating between astrocytomas and oligodendrogliomas.
  • Although annexin-1 expression in ependymomas decreased with the grade of malignancy, diffuse astrocytomas showed a significant increase in cytoplasmic annexin-1-positive tumor cells.
  • Thus, annexin-1 upregulation in astrocytomas may contribute to tumor progression and its expression profile is similar to its substrate, EGFR, suggesting a possible regulation thereof.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Astrocytoma / chemistry. Blotting, Western. Cell Nucleus / chemistry. Child. Child, Preschool. Ependymoma / chemistry. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Kaplan-Meier Estimate. Logistic Models. Male. Middle Aged. Neoplasm Staging. Oligodendroglioma / chemistry. Prognosis. Receptor, Epidermal Growth Factor / analysis. Reproducibility of Results. Reverse Transcriptase Polymerase Chain Reaction. Risk Assessment. Time Factors. Tissue Array Analysis. Young Adult

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19767728.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Annexin A1; 0 / Biomarkers, Tumor; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
  •  go-up   go-down


23. Franz DN, Leonard J, Tudor C, Chuck G, Care M, Sethuraman G, Dinopoulos A, Thomas G, Crone KR: Rapamycin causes regression of astrocytomas in tuberous sclerosis complex. Ann Neurol; 2006 Mar;59(3):490-8
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rapamycin causes regression of astrocytomas in tuberous sclerosis complex.
  • Five to 15% of affected individuals display subependymal giant cell astrocytomas, which can lead to substantial neurological and postoperative morbidity due to the production of hydrocephalus, mass effect, and their typical location adjacent to the foramen of Monro.
  • We sought to see whether therapy with oral rapamycin could affect growth or induce regression in astrocytomas associated with TSC.
  • METHODS: Five subjects with clinically definite TSC and either subependymal giant cell astrocytomas (n = 4) or a pilocytic astrocytoma (n = 1) were treated with oral rapamycin at standard immunosuppressive doses (serum levels 5-15 ng/ml) from 2.5 to 20 months.
  • Interruption of therapy resulted in regrowth of subependymal giant cell astrocytomas in one patient.
  • INTERPRETATION: Oral rapamycin therapy can induce regression of astrocytomas associated with TSC and may offer an alternative to operative therapy of these lesions.
  • [MeSH-major] Astrocytoma / drug therapy. Astrocytoma / etiology. Brain Neoplasms / drug therapy. Immunosuppressive Agents. Regression (Psychology). Sirolimus / therapeutic use. Tuberous Sclerosis / complications
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Dose-Response Relationship, Drug. Female. Humans. Magnetic Resonance Imaging / methods. Male. Models, Biological


24. Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C, von Deimling A: Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol; 2008 Dec;116(6):597-602
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We analyzed the genomic region spanning wild type R132 of IDH1 by direct sequencing in 685 brain tumors including 41 pilocytic astrocytomas, 12 subependymal giant cell astrocytomas, 7 pleomorphic xanthoastrocytomas, 93 diffuse astrocytomas, 120 adult glioblastomas, 14 pediatric glioblastomas, 105 oligodendrogliomas, 83 oligoastrocytomas, 31 ependymomas, 58 medulloblastomas, 9 supratentorial primitive neuroectodermal tumors, 17 schwannomas, 72 meningiomas and 23 pituitary adenomas.
  • A total of 221 somatic IDH1 mutations were detected and the highest frequencies occurred in diffuse astrocytomas (68%), oligodendrogliomas (69%), oligoastrocytomas (78%) and secondary glioblastomas (88%).
  • [MeSH-minor] Astrocytoma / genetics. Astrocytoma / pathology. Base Sequence. DNA Mutational Analysis. Disease Progression. Gene Frequency. Glioblastoma / genetics. Glioblastoma / pathology. Glioma / etiology. Glioma / pathology. Humans. Oligodendroglioma / genetics. Oligodendroglioma / pathology. Polymerase Chain Reaction

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18985363.001).
  • [ISSN] 1432-0533
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 1.1.1.41 / Isocitrate Dehydrogenase
  •  go-up   go-down


25. Maliszewski M, Majchrzak H: [Operative treatment of the intramedullary tumors with the methylprednisolone usage--preliminary report]. Wiad Lek; 2006;59(7-8):481-5
Hazardous Substances Data Bank. METHYLPREDNISOLONE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Among the operated tumors 16 had a clear border, the remaining ones were 14 astrocytomas of varying malignancy and infiltration of the white matter of the spinal cord and 3 lipomas.
  • [MeSH-major] Astrocytoma / surgery. Glioma, Subependymal / surgery. Methylprednisolone / administration & dosage. Neuroprotective Agents / administration & dosage. Neurosurgical Procedures / methods. Spinal Cord Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Survival Rate. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17209343.001).
  • [ISSN] 0043-5147
  • [Journal-full-title] Wiadomości lekarskie (Warsaw, Poland : 1960)
  • [ISO-abbreviation] Wiad. Lek.
  • [Language] pol
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Neuroprotective Agents; X4W7ZR7023 / Methylprednisolone
  •  go-up   go-down


26. Holveck A, Grand S, Boini S, Kirchin M, Le Bas JF, Dietemann JL, Bracard S, Kremer S: Dynamic susceptibility contrast-enhanced MRI evaluation of cerebral intraventricular tumors: preliminary results. J Neuroradiol; 2010 Dec;37(5):269-75
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A total of 28 patients with intraventricular tumors (five meningiomas, five papillomas, three ependymomas, four subependymomas, seven central neurocytomas, two subependymal giant cell astrocytomas and two metastases) underwent conventional and dynamic susceptibility contrast-enhanced MRI.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology. Ependymoma / pathology. Magnetic Resonance Imaging / methods. Meningioma / pathology. Neurocytoma / pathology. Papilloma / pathology
  • [MeSH-minor] Adult. Contrast Media. Female. Humans. Image Processing, Computer-Assisted. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20435349.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down


27. Tay A, Scheithauer BW, Cameron JD, Myhre MJ, Boerner MJ: Retinal ependymoma: an immunohistologic and ultrastructural study. Hum Pathol; 2009 Apr;40(4):578-83
Genetic Alliance. consumer health - Ependymoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Most are syndrome associated and include pilocytic astrocytoma in neurofibromatosis type 1 and subependymal giant cell astrocytoma in tuberous sclerosis complex.
  • Acquired, more conventional, diffuse astrocytomas are less frequent.
  • [MeSH-minor] Adult. Eye Evisceration. Female. Humans. Immunohistochemistry. Microscopy, Electron, Transmission. Retinal Detachment / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18835620.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


28. Gallagher A, Grant EP, Madan N, Jarrett DY, Lyczkowski DA, Thiele EA: MRI findings reveal three different types of tubers in patients with tuberous sclerosis complex. J Neurol; 2010 Aug;257(8):1373-81
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients with Type C tuber dominance have more MRI abnormalities such as subependymal giant cell tumors, and were more likely to have an autism spectrum disorder, a history of infantile spasms, and a higher frequency of epileptic seizures, compared to patients who have a dominance in Type B tubers, and especially to those with a Type A dominance.

  • Genetic Alliance. consumer health - Tuberous sclerosis.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • MedlinePlus Health Information. consumer health - Tuberous Sclerosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Neurology. 2000 May 23;54(10):1976-84 [10822440.001]
  • [Cites] Neurology. 2009 Mar 31;72(13):1165-9 [19332694.001]
  • [Cites] Am J Respir Crit Care Med. 2001 Jan;163(1):253-8 [11208653.001]
  • [Cites] Brain Dev. 2001 Nov;23(7):502-7 [11701245.001]
  • [Cites] Eur Radiol. 2002 Jan;12(1):138-43 [11868090.001]
  • [Cites] Epilepsy Res. 2003 Jan;52(3):203-13 [12536053.001]
  • [Cites] Psychol Med. 2003 Feb;33(2):335-44 [12622312.001]
  • [Cites] Arch Neurol. 2003 Nov;60(11):1580-4 [14623730.001]
  • [Cites] Arch Dis Child. 2004 Jun;89(6):530-3 [15155396.001]
  • [Cites] Neurology. 2004 Oct 26;63(8):1457-61 [15505165.001]
  • [Cites] Ann Neurol. 1981 Feb;9(2):174-81 [7235632.001]
  • [Cites] Mayo Clin Proc. 1991 Aug;66(8):792-6 [1861550.001]
  • [Cites] Radiology. 1992 Apr;183(1):227-38 [1549677.001]
  • [Cites] Acta Neuropathol. 1995;90(4):387-99 [8546029.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14152-7 [8943076.001]
  • [Cites] J Child Neurol. 1997 Feb;12(2):85-90 [9075016.001]
  • [Cites] Arch Neurol. 1998 Mar;55(3):379-84 [9520012.001]
  • [Cites] Acta Radiol. 1998 Sep;39(5):482-6 [9755694.001]
  • [Cites] Ann Neurol. 1998 Dec;44(6):858-66 [9851429.001]
  • [Cites] J Child Neurol. 2004 Sep;19(9):643-9 [15563009.001]
  • [Cites] J Child Neurol. 2004 Sep;19(9):650-7 [15563010.001]
  • [Cites] J Child Neurol. 2004 Sep;19(9):658-65 [15563011.001]
  • [Cites] Neurology. 2005 Jul 26;65(2):235-8 [16043792.001]
  • [Cites] Pediatr Radiol. 2006 Feb;36(2):119-25 [16283285.001]
  • [Cites] J Child Neurol. 2005 Oct;20(10):837-41 [16417883.001]
  • [Cites] Pediatr Radiol. 2006 Jun;36(6):498-501 [16568295.001]
  • [Cites] Diagn Interv Radiol. 2006 Jun;12(2):57-60 [16752348.001]
  • [Cites] Epilepsia. 2006 Sep;47(9):1543-9 [16981871.001]
  • [Cites] N Engl J Med. 2006 Sep 28;355(13):1345-56 [17005952.001]
  • [Cites] Neurology. 2007 Jan 2;68(1):62-4 [17200495.001]
  • [Cites] Genet Med. 2007 Feb;9(2):88-100 [17304050.001]
  • [Cites] AJNR Am J Neuroradiol. 2000 Mar;21(3):557-60 [10730651.001]
  • [Cites] J Am Acad Dermatol. 2007 Aug;57(2):189-202 [17637444.001]
  • [Cites] Trends Mol Med. 2007 Aug;13(8):319-26 [17632034.001]
  • [Cites] AJNR Am J Neuroradiol. 2007 Oct;28(9):1662-7 [17893226.001]
  • [Cites] Epilepsia. 2008;49 Suppl 2:53-62 [18226172.001]
  • [Cites] Neurology. 2008 Mar 18;70(12):916-23 [18032744.001]
  • [Cites] Neurology. 2008 Mar 18;70(12):908-15 [18032745.001]
  • [Cites] Epilepsia. 2009 Jan;50(1):147-54 [19125835.001]
  • [Cites] Am J Hum Genet. 2001 Jan;68(1):64-80 [11112665.001]
  • (PMID = 20352250.001).
  • [ISSN] 1432-1459
  • [Journal-full-title] Journal of neurology
  • [ISO-abbreviation] J. Neurol.
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / P01 NS024279; None / None / / P01 NS024279-23; United States / NINDS NIH HHS / NS / P01 NS024279-23; Canada / Canadian Institutes of Health Research / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Other-IDs] NLM/ NIHMS279080; NLM/ PMC3075858
  •  go-up   go-down


29. Pinto Gama HP, da Rocha AJ, Braga FT, da Silva CJ, Maia AC Jr, de Campos Meirelles RG, Mendonça do Rego JI, Lederman HM: Comparative analysis of MR sequences to detect structural brain lesions in tuberous sclerosis. Pediatr Radiol; 2006 Feb;36(2):119-25
MedlinePlus Health Information. consumer health - Tuberous Sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: We reviewed MR scans of 18 TS patients for the presence of cortical tubers, white matter lesions (radial bands), subependymal nodules, and subependymal giant cell astrocytoma (SGCA) on the following sequences:.
  • There was no significant difference between the T1 SE/MTC and T1 SE (before and after Gd injection) sequences in the detection of subependymal nodules; FLAIR sequence showed less sensitivity than the others in identifying the nodules.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Infant. Male. Reproducibility of Results. Retrospective Studies

  • Genetic Alliance. consumer health - Tuberous sclerosis.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Neuroradiology. 1997 Jul;39(7):523-8 [9258933.001]
  • [Cites] Magn Reson Med. 1989 Apr;10(1):135-44 [2547135.001]
  • [Cites] Neurophysiol Clin. 1991 Aug;21(3):161-72 [1944067.001]
  • [Cites] Radiology. 1994 Feb;190(2):541-6 [8284413.001]
  • [Cites] Arch Neurol. 2002 Feb;59(2):317-8 [11843708.001]
  • [Cites] Neuroradiology. 1987;29(5):437-43 [3683832.001]
  • [Cites] Brain Dev. 2000 Dec;22(8):487-93 [11111062.001]
  • [Cites] AJNR Am J Neuroradiol. 1995 Jan;16(1):149-55 [7900584.001]
  • [Cites] Neuroradiology. 1997 May;39(5):378-80 [9189887.001]
  • [Cites] AJNR Am J Neuroradiol. 1997 Aug;18(7):1367-73 [9282871.001]
  • [Cites] Neurology. 1999 Oct 22;53(7):1384-90 [10534239.001]
  • [Cites] AJNR Am J Neuroradiol. 1995 Oct;16(9):1923-8 [8693996.001]
  • [Cites] Ann N Y Acad Sci. 1991;615:125-7 [2039137.001]
  • [Cites] J Comput Assist Tomogr. 1995 Jul-Aug;19(4):660-1 [7622707.001]
  • [Cites] Radiology. 1988 May;167(2):527-32 [3357966.001]
  • [Cites] J Child Neurol. 1992 Apr;7(2):221-4 [1573244.001]
  • [Cites] J Dermatol. 1992 Nov;19(11):904-8 [1293181.001]
  • [Cites] Hum Mol Genet. 1997 Nov;6(12):2155-61 [9328481.001]
  • [Cites] AJNR Am J Neuroradiol. 2000 Mar;21(3):557-60 [10730651.001]
  • [Cites] Radiology. 1994 Sep;192(3):593-9 [8058919.001]
  • [Cites] Acta Radiol. 1998 Sep;39(5):482-6 [9755694.001]
  • [Cites] AJNR Am J Neuroradiol. 1999 May;20(5):907-16 [10369365.001]
  • [Cites] Neuropediatrics. 1997 Oct;28(5):244-52 [9413002.001]
  • [Cites] Neurology. 2001 Oct 9;57(7):1269-77 [11591847.001]
  • [Cites] Neurology. 2004 Oct 26;63(8):1457-61 [15505165.001]
  • [Cites] Science. 1997 Aug 8;277(5327):805-8 [9242607.001]
  • [Cites] Semin Pediatr Neurol. 1998 Dec;5(4):253-68 [9874853.001]
  • (PMID = 16283285.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


30. Osztie E, Hanzély Z, Afra D: Lateral ventricle gliomas and central neurocytomas in adults diagnosis and perspectives. Eur J Radiol; 2009 Jan;69(1):67-73
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eight subependymal giant cell astrocytomas also displayed hypodense, rarely hyperdense or mixed imaging characteristics, and always showed significant degree of contrast enhancement.
  • Ependymomas and anaplastic astrocytomas and glioblastomas followed the characteristics of the similar extraventricular ones.
  • In our series low-grade astrocytomas, WHO I-II [Louis DN, Ohgaki H, Wiestler OD, Canevee WK.
  • Survival data were available in 65 cases, which have confirmed a favourable outcome in most of the patients with subependymoma, subependymal giant cell astrocytoma, central neurocytomas or pilocytic astrocytoma.
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Reproducibility of Results. Sensitivity and Specificity. Young Adult

  • MedlinePlus Health Information. consumer health - CT Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18023315.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  •  go-up   go-down


31. Li WQ, Li YM, Lu YC, Yu HY: Bulky subependymal giant cell astrocytoma with profuse blood supply without tuberous sclerosis. Neurosciences (Riyadh); 2010 Oct;15(4):287-8
Genetic Alliance. consumer health - Tuberous sclerosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bulky subependymal giant cell astrocytoma with profuse blood supply without tuberous sclerosis.
  • [MeSH-minor] Adult. Astrocytoma / complications. Astrocytoma / diagnosis. Brain Neoplasms / complications. Brain Neoplasms / diagnosis. Humans. Magnetic Resonance Imaging. Male. Tuberous Sclerosis / physiopathology

  • Genetic Alliance. consumer health - Subependymal giant cell astrocytoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20956931.001).
  • [ISSN] 1319-6138
  • [Journal-full-title] Neurosciences (Riyadh, Saudi Arabia)
  • [ISO-abbreviation] Neurosciences (Riyadh)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
  •  go-up   go-down


32. Dickerman RD, Cohen A: Subependymal giant cell astrocytoma and concordant expression in a disease of variable penetrance. Neurosurg Rev; 2005 Oct;28(4):335-6
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subependymal giant cell astrocytoma and concordant expression in a disease of variable penetrance.
  • [MeSH-major] Astrocytoma / genetics. Brain Neoplasms / genetics. Penetrance
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Siblings. Ventriculoperitoneal Shunt

  • Genetic Alliance. consumer health - Subependymal giant cell astrocytoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Neurosurg Rev. 2004 Oct;27(4):274-80 [15309659.001]
  • [Cites] Neurosurg Rev. 2004 Oct;27(4):274-80 [15309659.001]
  • [Cites] Pol Arch Med Wewn. 2003 Aug;110(2):877-84 [14682227.001]
  • [Cites] Neurology. 2004 Mar 9;62(5):795-8 [15007135.001]
  • [Cites] Hum Mol Genet. 1996 Feb;5(2):249-56 [8824881.001]
  • [Cites] J Dermatol. 1991 Mar;18(3):178-80 [1885853.001]
  • [Cites] Eur J Hum Genet. 2005 Jun;13(6):731-41 [15798777.001]
  • [Cites] Indian J Med Res. 2004 Oct;120(4):233-47 [15520480.001]
  • (PMID = 16041550.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Germany
  •  go-up   go-down






Advertisement