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Items 1 to 29 of about 29
1. Mastrangelo S, Lauriola L, Coccia P, Puma N, Massimi L, Riccardi R: Two cases of pediatric high-grade astroblastoma with different clinical behavior. Tumori; 2010 Jan-Feb;96(1):160-3
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  • [Title] Two cases of pediatric high-grade astroblastoma with different clinical behavior.
  • Astroblastoma is a rare glial tumor occurring in older children and defined by histological criteria as low or high-grade.
  • We describe two children with high-grade astroblastoma.
  • Although both patients had high-grade astroblastomas, there were histological differences between the two tumors, in particular regarding the proliferative index, which was 30% and 5-10%, respectively.
  • High-grade astroblastoma is usually treated with surgery and radiotherapy, but may have an unpredictable behavior even when tumor excision is deemed complete.

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  • (PMID = 20437876.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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2. Eom KS, Kim JM, Kim TY: A Cerebral Astroblastoma Mimicking an Extra-axial Neoplasm. J Korean Neurosurg Soc; 2008 Apr;43(4):205-8

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  • [Title] A Cerebral Astroblastoma Mimicking an Extra-axial Neoplasm.
  • Astroblastoma is a rarely diagnosed primary brain neoplasm whose histogenesis has been clarified recently.
  • We present a case of 20-year-old woman with an astroblastoma in the left temporal convexity that was treated with total tumor resection alone.
  • An astroblastoma should be included in the differential diagnosis of a superficially located tumor presenting with the findings of an extra-axial mass, especially in a young patient.

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  • [Cites] Neuroradiology. 2007 Mar;49(3):203-9 [17216265.001]
  • [Cites] Surg Neurol. 2007 Mar;67(3):308-13 [17320647.001]
  • [Cites] Neuropathology. 2006 Feb;26(1):72-81 [16521483.001]
  • [Cites] Childs Nerv Syst. 2005 Mar;21(3):211-20 [15654633.001]
  • [Cites] Brain Pathol. 2000 Jul;10(3):342-52 [10885653.001]
  • [Cites] J Neurosurg. 1995 Sep;83(3):550-5 [7545227.001]
  • [Cites] Neurosurgery. 1989 Jul;25(1):6-13 [2755581.001]
  • [Cites] Acta Neurochir (Wien). 2004 Jun;146(6):629-33 [15168232.001]
  • [Cites] J Neuroradiol. 1996 Jun;23(1):38-40 [8767917.001]
  • (PMID = 19096646.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588258
  • [Keywords] NOTNLM ; Astroblastoma / Intra-axial neoplasm
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3. Kemerdere R, Dashti R, Ulu MO, Biçeroğlu H, Demiröz AS, Albayram S, Erdinçler P: Supratentorial high grade astroblastoma: report of two cases and review of the literature. Turk Neurosurg; 2009 Apr;19(2):149-52
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  • [Title] Supratentorial high grade astroblastoma: report of two cases and review of the literature.
  • Astroblastoma is a rare glial tumor with uncertain histopathological origin and unpredictable clinical behavior.
  • In this report, the authors present two cases of high grade intracerebral astroblastomas.

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  • (PMID = 19431125.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 19
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4. Miranda P, Lobato RD, Cabello A, Gómez PA, Martínez de Aragón A: Complete surgical resection of high-grade astroblastoma with long time survival: case report and review of the literature. Neurocirugia (Astur); 2006 Feb;17(1):60-3
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  • [Title] Complete surgical resection of high-grade astroblastoma with long time survival: case report and review of the literature.
  • Astroblastoma is a rare glial neoplasm of unknown origin and uncertain prognosis.
  • The histological features of astroblastoma are the presence of typical astroblastic perivascular pseudorosettes and perivascular hyalinization.
  • Two different subtypes of astroblastoma have been defined based upon histological characteristics.
  • We present a new case of a patient with a high-grade astroblastoma with a long survival time, in whom complete surgical resection was confirmed by an early postoperative MRI.

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  • (PMID = 16565782.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 21
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5. Hata N, Shono T, Yoshimoto K, Mizoguchi M, Kawamura T, Nagata S, Matsumoto K, Hayashi K, Iwaki T, Sasaki T: An astroblastoma case associated with loss of heterozygosity on chromosome 9p. J Neurooncol; 2006 Oct;80(1):69-73
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  • [Title] An astroblastoma case associated with loss of heterozygosity on chromosome 9p.
  • The tumorigenesis of astroblastomas has not yet been elucidated on the basis of histopathological studies, and genetic studies may be useful for obtaining additional information regarding the tumorigenesis of these tumors.
  • Here, we report an astroblastoma case in which a genetic analysis was performed.
  • Total removal of the tumor was achieved and a histological examination verified that the tumor was an astroblastoma.
  • This is the first reported case of an astroblastoma in which LOH was detected on 9p.
  • Based on this result, the tumorigenesis of astroblastomas is discussed.


6. Unal E, Koksal Y, Vajtai I, Toy H, Kocaogullar Y, Paksoy Y: Astroblastoma in a child. Childs Nerv Syst; 2008 Feb;24(2):165-8
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  • [Title] Astroblastoma in a child.
  • BACKGROUND: Astroblastoma, an uncommon neuroepithelial tumor, typically presents in young adults as a well-circumscribed cortical or subcortical spherical mass.
  • Astroblastoma may cause a diagnostic problem to anyone unfamiliar with its architectural and histological features.
  • Total removal of the tumor mass was performed, and a diagnosis of high grade (malignant) variant of astroblastoma was made.
  • PROGNOSIS: The best treatment modality for astroblastoma is surgical resection if possible, whereas adjuvant therapy (radiotherapy and/or chemotherapy) can be considered in high-grade astroblastomas, with a close follow-up for all cases.

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  • (PMID = 17653728.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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7. Ganapathy S, Kleiner LI, Mirkin DL, Broxson E: Unusual manifestations of astroblastoma: a radiologic-pathologic analysis. Pediatr Radiol; 2009 Feb;39(2):168-71
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  • [Title] Unusual manifestations of astroblastoma: a radiologic-pathologic analysis.
  • Astroblastoma is a very rare primary glial tumor occurring in children and young adults that is almost exclusively supratentorial in location.
  • We report an extremely unusual presentation of a densely calcified posterior fossa astroblastoma with disseminated spinal and supratentorial metastasis.
  • The mass exhibited neoplastic bone formation, which has not been reported, although calcifications are commonly seen in astroblastomas.
  • A companion case of a low-grade astroblastoma that demonstrated classic histologic features but nonspecific and atypical imaging findings is also included.

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  • (PMID = 18958463.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 8
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8. Kaji M, Takeshima H, Nakazato Y, Kuratsu J: Low-grade astroblastoma recurring with extensive invasion. Neurol Med Chir (Tokyo); 2006 Sep;46(9):450-4
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  • [Title] Low-grade astroblastoma recurring with extensive invasion.
  • The histological diagnosis was low-grade astroblastoma.
  • Although gross total resection of astroblastoma usually results in long-term survival, some of these yet unfamiliar tumors may develop a more malignant character.

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  • (PMID = 16998280.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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9. Kubota T, Sato K, Arishima H, Takeuchi H, Kitai R, Nakagawa T: Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation. Neuropathology; 2006 Feb;26(1):72-81
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  • [Title] Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation.
  • We report the clinicopathological findings of astroblastoma found in an 8-year-old girl who was subsequently treated for 11 years.
  • The tumor cells showed typical features of astroblastoma comprising prominent perivascular pseudorosettes with remarkable vascular sclerosis.
  • We report these unique histological features, and stress that astroblastoma should be categorized as a specific type of neuroepithelial tumor.

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  • (PMID = 16521483.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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10. Scheithauer BW, Aker AT, Ketterling RP, Carlson AW, Knudson RA, Tyler M: Anaplastic astroblastoma-sarcoma in neurofibromatosis Type 1. Clin Neuropathol; 2010 Sep-Oct;29(5):289-96
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  • [Title] Anaplastic astroblastoma-sarcoma in neurofibromatosis Type 1.
  • Astroblastoma is a distinctive brain tumor when its histologic features occur in pure form.
  • Astroblastoma as a de novo component of gliosarcoma has not previously been described.
  • Furthermore, astroblastoma has only once been reported to occur in the setting of neurofibromatosis Type I (NF1), a condition more often associated with pilocytic and diffuse or infiltrative astrocytic tumors.
  • Herein, we describe a unique case of anaplastic de novo astroblastoma-sarcoma, in essence a variant of gliosarcoma, occurring in a 50-year-old female with documented NF1.
  • The latter alterations, having been reported in astroblastoma, were noted in both tumor components, thus confirming the common origin of the glial and sarcomatous elements.


11. Lau PP, Thomas TM, Lui PC, Khin AT: 'Low-grade' astroblastoma with rapid recurrence: a case report. Pathology; 2006 Feb;38(1):78-80
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  • [Title] 'Low-grade' astroblastoma with rapid recurrence: a case report.

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  • (PMID = 16484017.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Mucin-1; 0 / S100 Proteins
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12. Mangano FT, Bradford AC, Mittler MA, Valderrama E, Schneider SJ: Astroblastoma. Case report, review of the literature, and analysis of treatment strategies. J Neurosurg Sci; 2007 Mar;51(1):21-7; discussion 27
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  • [Title] Astroblastoma. Case report, review of the literature, and analysis of treatment strategies.
  • Astroblastoma, a unique glial tumor, has been described in the literature in case reports and small series.
  • After tumor resection, histological diagnosis revealed a high-grade cerebral astroblastoma.
  • Since the first description of astroblastoma, its histopathological and clinical features have been debated.
  • We review the histology, immunohistochemistry, and cytogenetics of astroblastoma as well as examine the current literature and treatment strategies for the management of both low and high-grade tumors.

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  • (PMID = 17369788.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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13. Notarianni C, Akin M, Fowler M, Nanda A: Brainstem astroblastoma: a case report and review of the literature. Surg Neurol; 2008 Feb;69(2):201-5
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  • [Title] Brainstem astroblastoma: a case report and review of the literature.
  • BACKGROUND: Astroblastoma is a rare glial tumor that occurs mainly in the cerebral hemispheres of young adults.
  • Our purpose in writing this article is to report one case of astroblastoma located within the medulla and review the literature on this infrequent tumor.
  • METHODS: One case of astroblastoma was retrospectively reviewed.
  • CONCLUSIONS: The combination of the radiologic and histopathologic characteristics of this tumor is necessary for making the diagnosis of astroblastoma.

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  • (PMID = 17765957.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 21
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14. Johnson KA, Bonnin JM, Boaz JC, Douglas-Akinwande AC, Hattab EM: Anaplastic astroblastoma presenting as massive, sudden-onset, intraparenchymal hemorrhage. Pediatr Neurosurg; 2010;46(6):457-61
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  • [Title] Anaplastic astroblastoma presenting as massive, sudden-onset, intraparenchymal hemorrhage.
  • Astroblastoma is a rare primary glial tumor of children and young adults, typically located in the cerebral hemispheres and presenting as a well-circumscribed, nodular, often cystic enhancing mass.
  • The existence of astroblastoma as a distinct clinicopathologic entity has long been debated but is recognized in the 2007 WHO classification of CNS tumors.
  • Astroblastomas in general are thought to have a favorable outcome with low rates of recurrence following gross total resection.
  • We report a case of astroblastoma with 'high-grade/anaplastic' histology in a 12-year-old, previously healthy girl.
  • The diagnosis of anaplastic astroblastoma was rendered.
  • This case illustrates the potential poor outcome of high-grade astroblastoma and highlights the morphologic heterogeneity of this rare neoplasm.

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  • [Copyright] Copyright © 2011 S. Karger AG, Basel.
  • (PMID = 21540623.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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15. Salvati M, D'Elia A, Brogna C, Frati A, Antonelli M, Giangaspero F, Raco A, Santoro A, Delfini R: Cerebral astroblastoma: analysis of six cases and critical review of treatment options. J Neurooncol; 2009 Jul;93(3):369-78
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  • [Title] Cerebral astroblastoma: analysis of six cases and critical review of treatment options.
  • Astroblastoma is one of the rarest tumors of the central nervous system (CNS), and its classification, histogenesis, diagnosis and therapeutic management are still being debated.
  • To clarify the clinical, radiological, histopathological, prognostic and therapeutic characteristics, which have been treated only recently and are not well established yet due to the rarity of this tumor, six cases of histologically proven astroblastoma were retrospectively analyzed in light of more pertinent literature and paying special attention to therapeutic remarks.
  • Between 1996 and 2005, six patients with cerebral astroblastoma were surgically treated at the Department of Neurosciences-Neurosurgery of Sapienza University in Rome.
  • In three cases the lesion was termed low-grade astroblastoma, and high grade in the other three, according to current standard parameters.
  • The three patients with low-grade astroblastoma are still alive today after a follow-up of 2, 5 and 19 years, respectively.
  • Conclusions radical surgical resection is the treatment of choice for astroblastomas.
  • We propose an aggressive standardized treatment for those lesions that meet anaplastic criteria, owing to their postulated glial origin and the propensity to have aggressive courses, and we advocate the use of a safe adjuvant chemotherapeutic regimen with TMZ, used concomitantly and subsequently to radiotherapy, especially for the high-grade astroblastoma cases.
  • Multicenter studies, taking into account molecular biological findings, are necessary to define a common therapeutic strategy for astroblastomas.

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  • (PMID = 19214707.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 34
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16. Cowart JR, Schulman FY, Mena H: Low-grade glial tumor with features of astroblastoma in a dog. Vet Pathol; 2005 May;42(3):366-9

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  • [Title] Low-grade glial tumor with features of astroblastoma in a dog.
  • These features are consistent with an astroblastoma.
  • This is the first clinicopathologic correlation and detailed description of a low-grade glial tumor with features of astroblastoma in a dog.

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  • (PMID = 15872386.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Tumialán LM, Brat DJ, Fountain AJ, Barrow DL: An astroblastoma mimicking a cavernous malformation: case report. Neurosurgery; 2007 Mar;60(3):E569-70; discussion E570
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  • [Title] An astroblastoma mimicking a cavernous malformation: case report.
  • OBJECTIVE: Astroblastomas are rare glial neoplasms that usually occur in young adults and have a predilection for the cerebral hemispheres.
  • An astroblastoma was diagnosed after resection and neuropathological examination.
  • CONCLUSION: A rare radiological to pathological correlation of astroblastoma is presented in which the evolving hematoma, as observed on magnetic resonance imaging scans, complicated the radiographic diagnosis of this lesion.
  • The clinical, radiographic, and pathological features of astroblastomas, as well as the natural history of these rare glial neoplasms, are reviewed.
  • This case illustrates the capacity of astroblastomas to hemorrhage, disguising the classic radiographic findings typical of this glial neoplasm.

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  • (PMID = 17327764.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Navarro R, Reitman AJ, de León GA, Goldman S, Marymont M, Tomita T: Astroblastoma in childhood: pathological and clinical analysis. Childs Nerv Syst; 2005 Mar;21(3):211-20
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  • [Title] Astroblastoma in childhood: pathological and clinical analysis.
  • OBJECT: The object was to describe the clinical, radiologic, and pathologic features of astroblastomas in an unselected group of children who were treated in a single institution during an 11-year period.
  • METHODS: Eight children with astroblastomas of the brain were examined.
  • CONCLUSIONS: Clinical findings seem to confirm an apparent predilection of astroblastomas for younger children (median age of onset, 5 years) and the existence of two prognostically different types of tumor-well differentiated (low grade) and anaplastic (high grade).

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  • (PMID = 15654633.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
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19. Huhn SL, Yung Y, Cheshier S, Harsh G, Ailles L, Weissman I, Vogel H, Tse V: Identification of phenotypic neural stem cells in a pediatric astroblastoma. J Neurosurg; 2005 Nov;103(5 Suppl):446-50
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  • [Title] Identification of phenotypic neural stem cells in a pediatric astroblastoma.
  • OBJECT: The goal of this study was to illustrate the findings of a significant subpopulation of cells within a pediatric astroblastoma that have the specific cell surface phenotype found on known human neural stem cells.
  • METHODS: Cells with a cell surface marker profile characteristic of human neural stem cells were isolated using fluorescence-activated cell sorting from a mostly nonmitotic astroblastoma removed from the brain of an 11-year-old girl.
  • CONCLUSIONS: Although this astroblastoma contained a high proportion of phenotypic neural stemlike cells, the cells had limited proliferative capacity and multipotency.
  • Their role in astroblastoma formation and growth is unknown.


20. Alaraj A, Chan M, Oh S, Michals E, Valyi-Nagy T, Hersonsky T: Astroblastoma presenting with intracerebral hemorrhage misdiagnosed as dural arteriovenous fistula: review of a rare entity. Surg Neurol; 2007 Mar;67(3):308-13
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  • [Title] Astroblastoma presenting with intracerebral hemorrhage misdiagnosed as dural arteriovenous fistula: review of a rare entity.
  • BACKGROUND: Astroblastoma is one of the most unusual types of tumors whose histogenesis has been recently clarified.
  • The lesion was resected, and pathology showed a GFAP-positive lesion with prominent astroblastoma rosettes.
  • CONCLUSIONS: Astroblastoma is a rare pure pathologic entity--a distinct form of astrocytic gliomas.
  • The diagnosis of astroblastoma is often difficult because of the astroblastic aspects that can be found in astrocytic tumors, in ependymomas, and in nonneuroepithelial tumors.

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  • (PMID = 17320647.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Fathi AR, Novoa E, El-Koussy M, Kappeler A, Mariani L, Vajtai I: Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up. Pathol Res Pract; 2008;204(5):345-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up.
  • Astroblastoma is a historically traded microscopic diagnosis to denote a rare neuroepithelial tumor of uncertain nosology, involving a distinctive pattern of pseudorosette arrangement of neoplastic cells.
  • We report on clinicopathologic correlations in a case of astroblastoma involving an extensive rhabdoid phenotype of tumor cells.
  • A review of pathology samples from both surgeries showed well-differentiated astroblastoma according to current standards, with an MIB-1 labeling index of 1% and 4%, respectively.

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  • (PMID = 18280055.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / Antineoplastic Agents, Alkylating; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / MIB-1 antibody; 0 / Vimentin; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide
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22. Kantar M, Ertan Y, Turhan T, Kitis O, Anacak Y, Akalin T, Ersahin Y, Cetingül N: Anaplastic astroblastoma of childhood: aggressive behavior. Childs Nerv Syst; 2009 Sep;25(9):1125-9
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  • [Title] Anaplastic astroblastoma of childhood: aggressive behavior.
  • OBJECTIVE: Astroblastoma is an unusual brain tumor in childhood.
  • Histopathologically, there are two types of astroblastoma: well-differentiated (low-grade) or anaplastic (high-grade).
  • In low-grade astroblastoma, treatment of choice is complete excision.
  • Histopathologically, the tumor was an anaplastic astroblastoma.
  • CONCLUSION: High-grade astroblastomas behave like glioblastoma, as emphasized in this case report.

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  • (PMID = 19357852.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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23. Denaro L, Gardiman M, Calderone M, Rossetto M, Ciccarino P, Giangaspero F, Perilongo G, d'Avella D: Intraventricular astroblastoma. Case report. J Neurosurg Pediatr; 2008 Feb;1(2):152-5
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  • [Title] Intraventricular astroblastoma. Case report.
  • Astroblastoma is a rare primary brain neoplasm that accounts for 0.45-2.8% of brain gliomas.
  • The authors report a case of well-differentiated completely intraventricular astroblastoma in a 6-year-old girl and review the relevant literature.
  • In patients harboring anaplastic astroblastoma, gross-total resection and adjuvant therapy after the initial surgery seems to be the best choice.
  • It is important to distinguish astroblastoma from ependymoma in clinical practice because of the differences in therapeutic approaches.

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  • (PMID = 18352788.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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24. Fan YS, Lui PC, Tam FK, Hung KN, Ng HK, Leung SY: A 33-year-old Chinese woman with a left frontal tumor. Brain Pathol; 2009 Apr;19(2):337-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Rhabdoid tumor cells are typically observed in atypical teratoid/rhabdoid tumor (AT/RT) but may also be seen in meningioma,glioma, melanoma, rhabdomyosarcoma and metastatic carcinoma.We present an astroblastoma with unusual rhabdoid features which is rarely described in the English literature.
  • Apart from the rhabdoid tumor cells, all the histopathological features typical for astroblastoma are present in this case.
  • The diagnosis of astroblastoma is also well supported by the age of presentation, anatomical location and radiological features of the tumor.We believe that on top of the above-mentioned unusual tumors with rhabdoid cells, astroblastoma should also be considered in the list of differential diagnosis.

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  • (PMID = 19291001.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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25. Hirano H, Yunoue S, Kaji M, Tsuchiya M, Arita K: Consecutive histological changes in an astroblastoma that disseminated to the spinal cord after repeated intracranial recurrences: a case report. Brain Tumor Pathol; 2008;25(1):25-31
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  • [Title] Consecutive histological changes in an astroblastoma that disseminated to the spinal cord after repeated intracranial recurrences: a case report.
  • After the third surgery, this case was reported as a low-grade astroblastoma that is characterized by perivascular pseudorosettes consisting of elongated tumor cells arranged around the blood vessels.
  • However, the fourth and fifth surgical specimens demonstrated very interesting histological changes in the astroblastoma.
  • Some astroblastomas may be more immature than the usual astrocytes; however, it is necessary to study more cases to confirm this.

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  • (PMID = 18415663.001).
  • [ISSN] 1433-7398
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Glial Fibrillary Acidic Protein; EC 4.2.1.11 / Phosphopyruvate Hydratase
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26. Bannykh SI, Fan X, Black KL: Malignant astroblastoma with rhabdoid morphology. J Neurooncol; 2007 Jul;83(3):277-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant astroblastoma with rhabdoid morphology.

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  • (PMID = 17332948.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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27. Bell JW, Osborn AG, Salzman KL, Blaser SI, Jones BV, Chin SS: Neuroradiologic characteristics of astroblastoma. Neuroradiology; 2007 Mar;49(3):203-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neuroradiologic characteristics of astroblastoma.
  • INTRODUCTION: Astroblastoma is a rare glial tumor of uncertain origin.
  • We report the largest imaging series to date and further delineate the CT and MRI features of astroblastoma.
  • We identify those features that may be useful in distinguishing astroblastoma from other neoplasms.
  • METHODS: The radiologic images, pathology reports, and clinical information of 12 patients with pathology-confirmed astroblastoma were retrospectively reviewed.
  • CONCLUSION: The imaging features of astroblastoma are identified in 12 previously unreported cases.


28. Lehman NL: Central nervous system tumors with ependymal features: a broadened spectrum of primarily ependymal differentiation? J Neuropathol Exp Neurol; 2008 Mar;67(3):177-88
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Several other CNS tumor entities, including astroblastoma, chordoid glioma, papillary tumor of the pineal region, angiocentric glioma, and pilomyxoid astrocytoma, variably display histopathologic features of ependymal differentiation.
  • These issues are addressed in the context of early morphologic insights of Bailey and Cushing, Friede, and others; contemporary oncologic concepts; and recent relevant molecular and tumor stem cell studies.

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  • (PMID = 18344909.001).
  • [ISSN] 0022-3069
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / K08 NS45077
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 81
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29. Leeds NE, Lang FF, Ribalta T, Sawaya R, Fuller GN: Origin of chordoid glioma of the third ventricle. Arch Pathol Lab Med; 2006 Apr;130(4):460-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: Chordoid glioma is a relatively recently described unique glial neoplasm that has been formally codified by the World Health Organization in Pathology and Genetics of Tumours of the Nervous System, in which it is included along with astroblastoma and gliomatosis cerebri under the rubric "Tumors of Uncertain Origin."

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  • [CommentIn] Arch Pathol Lab Med. 2006 Apr;130(4):437-8 [16594734.001]
  • (PMID = 16594739.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / Vimentin
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