[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 32 of about 32
1. Kara Gedik G, Sari O, Altinok T, Tavli L, Kaya B, Ozcan Kara P: Askin's Tumor in an Adult: Case Report and Findings on 18F-FDG PET/CT. Case Rep Med; 2009;2009:517329

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Askin's Tumor in an Adult: Case Report and Findings on 18F-FDG PET/CT.
  • Primitive neuroectodermal tumor (PNET) of the chest wall or Askin's tumor is a rare neoplasm of chest wall.
  • It most often affects children and adolescents and is a very rare tumor in adults.
  • In this case report, we present an Askin's tumor occurred in a 73-year-old male.
  • Positron emission tomography/computed tomography with 18F-flourodeoxyglucose revealed a pleural-based tumor in the left lung with a maximum standardized uptake value of 4.36.
  • Pathology report with immunocytochemistry was consistent with PNET and the patient received chemotherapy after that.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] AJR Am J Roentgenol. 2005 Apr;184(4):1293-304 [15788613.001]
  • [Cites] Pediatr Radiol. 1998 Sep;28(9):697-702 [9732497.001]
  • [Cites] J Thorac Cardiovasc Surg. 1994 Mar;107(3):960-2 [8127136.001]
  • [Cites] Clin Radiol. 1991 Jan;43(1):19-23 [1847850.001]
  • [Cites] J Radiol. 1990 Mar;71(3):233-6 [2161926.001]
  • [Cites] Chest. 1990 May;97(5):1252-4 [2331925.001]
  • [Cites] Cancer. 1979 Jun;43(6):2438-51 [222426.001]
  • [Cites] Spine (Phila Pa 1976). 2003 Oct 1;28(19):E408-12 [14520055.001]
  • [Cites] Pediatr Blood Cancer. 2007 Dec;49(7):901-5 [17252575.001]
  • [Cites] Thorax. 2007 Aug;62(8):696-701 [17687098.001]
  • [Cites] Nucl Med Commun. 2006 Jan;27(1):17-24 [16340719.001]
  • (PMID = 20049330.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2797374
  •  go-up   go-down


2. Vukasinović Z, Stevanović V, Spasovski D, Zivković Z: [Ewing sarcoma--current opinion]. Srp Arh Celok Lek; 2006 Jul-Aug;134(7-8):348-55
Genetic Alliance. consumer health - Ewing's Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ewing tumor family consists of Ewing tumor of bone, extraosseous Ewing tumor, primitive neurectodermal tumor and Askin tumor.
  • All of them share genetic abnormality, reciprocal translocation (11;.
  • 22) (q24; q12), and originate from the same primordial stem cell.
  • Ewing tumor is the most common form, found in 60% of cases.
  • It is the second primary malignant bone tumor.
  • Ewing tumor can develop in virtually any bone of the body and in extraosseous localizations as well, while localization in the extremities occurs in 50% of patients.
  • Paraspinal, retroperitoneal or deep pelvic tumor localization is manifested by back pain.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17009618.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Serbia and Montenegro
  • [Number-of-references] 26
  •  go-up   go-down


3. Peres E, Mattoo TK, Poulik J, Warrier I: Primitive neuroectodermal tumor (PNET) of the uterus in a renal allograft patient: a case report. Pediatr Blood Cancer; 2005 Mar;44(3):283-5
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primitive neuroectodermal tumor (PNET) of the uterus in a renal allograft patient: a case report.
  • Tumors of the skin and lip tend to be the most common with non-Hodgkin lymphoma comprising 20% of all neoplasms.
  • Primitive neuroectodermal tumors (PNET) are collectively described as being a part of the Ewing sarcoma family of tumors.
  • PNET occur more commonly in the second decade of life, predominantly affecting Whites and Hispanics, and rarely occur in individuals of African or Asian descent.
  • The most common primary site of involvement is along the central axis, particularly the chest (Askin tumor), but it can arise in any soft tissue.
  • PNET also occur in the head and neck.
  • PNET involving the cervix, urinary bladder, uterus, and vagina have been reported.
  • We describe a case of a 15-year-old female who, 9 years after receiving a living related renal transplant, developed a post-transplant PNET of the uterus.
  • [MeSH-major] Kidney Transplantation. Neuroectodermal Tumors, Primitive / etiology. Uterine Neoplasms / etiology

  • MedlinePlus Health Information. consumer health - Kidney Transplantation.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2004 Wiley-Liss, Inc.
  • (PMID = 15481061.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


Advertisement
4. Cabello-Bautista JM, Domínguez-Pérez AD, Iribarren-Marín MA: [Intrapulmonary Askin tumour: an unusual form of presentation]. Arch Bronconeumol; 2010 Aug;46(8):446
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intrapulmonary Askin tumour: an unusual form of presentation].
  • [Transliterated title] Tumor de Askin intrapulmonar. Una forma inusual de presentación.
  • [MeSH-major] Lung Neoplasms / diagnosis. Neuroectodermal Tumors, Primitive, Peripheral / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20580149.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
  •  go-up   go-down


5. Verfaillie G, Hoorens A, Lamote J: Primary primitive neuro-ectodermal tumour of the lung. Acta Chir Belg; 2009 May-Jun;109(3):381-4
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary primitive neuro-ectodermal tumour of the lung.
  • A case of intrapulmonary primitive neuro-ectodermal tumour (PNET) without thoracic wall involvement is presented in a 33-year-old man.
  • PNET of the thoracopulmonary region, also called Askin tumour, is a rare undifferentiated sarcoma usually involving the thoracic wall.
  • Primary intrapulmonary PNET without parietal pleura or thoracic wall involvement is very rare.
  • [MeSH-major] Lung Neoplasms / diagnosis. Neuroectodermal Tumors, Primitive / diagnosis. Pneumonectomy / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19943597.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
  •  go-up   go-down


6. Torres Sousa MY, Banegas Illescas ME: [Solution to case 9. Askin tumor]. Radiologia; 2009 Sep-Oct;51(5):529-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solution to case 9. Askin tumor].
  • [Transliterated title] Solución del caso 9. Tumor de Askin.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19800487.001).
  • [ISSN] 0033-8338
  • [Journal-full-title] Radiología
  • [ISO-abbreviation] Radiologia
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


7. Scurr M, Judson I: How to treat the Ewing's family of sarcomas in adult patients. Oncologist; 2006 Jan;11(1):65-72
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ewing's sarcoma, peripheral primitive neuroectodermal tumor, and Askin's tumor comprise a single family of tumors, the Ewing's family of tumors, which is characterized by chromosomal translocation.
  • This article examines whether age does affect outcome and treatment in this group of tumors.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16401715.001).
  • [ISSN] 1083-7159
  • [Journal-full-title] The oncologist
  • [ISO-abbreviation] Oncologist
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 51
  •  go-up   go-down


8. Ma C, Bower KA, Chen G, Shi X, Ke ZJ, Luo J: Interaction between ERK and GSK3beta mediates basic fibroblast growth factor-induced apoptosis in SK-N-MC neuroblastoma cells. J Biol Chem; 2008 Apr 4;283(14):9248-56
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The Ewing's sarcoma family of tumors (ESFT) includes Ewing's sarcoma (ES), Askin's tumor of the chest wall, and peripheral primitive neuroectodermal tumor.
  • Using a human peripheral primitive neuroectodermal tumor cell line, SK-N-MC, we demonstrated FGF2 stimulated phosphorylation of ERK1 and ERK2 (pERK1/2) and GSK3beta (pGSK3beta(Tyr-216)), all of which were primarily retained in the cytoplasm.
  • Similarly, expression of a kinase-deficient (K85R) GSK3beta or GSK3beta-small interfering RNA inhibited FGF2-regulated ERK/pGSK3beta(Tyr-216) association and translocated pERK to the nucleus.
  • Both K85R GSK3beta and small interfering RNA offered protection against FGF2-induced cell death.
  • As a result, they potentiated FGF2-induced cell death.

  • Genetic Alliance. consumer health - Neuroblastoma.
  • MedlinePlus Health Information. consumer health - Neuroblastoma.
  • PhosphoSitePlus. gene/protein/disease-specific - PhosphoSitePlus® - comprehensive post-translational modification resource .
  • Hazardous Substances Data Bank. ETHANOL .
  • Hazardous Substances Data Bank. HYDROGEN PEROXIDE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Curr Opin Cell Biol. 2001 Apr;13(2):139-45 [11248546.001]
  • [Cites] J Biol Chem. 1999 Jul 23;274(30):21395-401 [10409701.001]
  • [Cites] Brain Pathol. 2001 Apr;11(2):144-58 [11303790.001]
  • [Cites] Development. 2001 Jun;128(11):2119-29 [11493533.001]
  • [Cites] Anat Embryol (Berl). 2001 Sep;204(3):171-7 [11681796.001]
  • [Cites] Apoptosis. 2002 Feb;7(1):5-12 [11773700.001]
  • [Cites] J Neural Transm (Vienna). 2001;108(12):1397-415 [11810404.001]
  • [Cites] J Biol Chem. 2002 Nov 8;277(45):43377-88 [12218054.001]
  • [Cites] Am J Pathol. 2002 Dec;161(6):2087-98 [12466125.001]
  • [Cites] J Biol Chem. 2003 Feb 21;278(8):6258-67 [12473660.001]
  • [Cites] J Cell Sci. 2003 Apr 1;116(Pt 7):1175-86 [12615961.001]
  • [Cites] J Biol Chem. 2003 Apr 18;278(16):14498-506 [12574160.001]
  • [Cites] J Pathol. 2004 Jan;202(1):103-12 [14694527.001]
  • [Cites] Biochem Biophys Res Commun. 2004 Apr 2;316(2):411-5 [15020233.001]
  • [Cites] J Biol Chem. 2004 Mar 19;279(12):10962-72 [14701865.001]
  • [Cites] Free Radic Biol Med. 2004 May 1;36(9):1112-25 [15082065.001]
  • [Cites] J Biol Chem. 2004 Nov 12;279(46):47912-28 [15310753.001]
  • [Cites] Cytokine Growth Factor Rev. 2005 Apr;16(2):139-49 [15863030.001]
  • [Cites] Cytokine Growth Factor Rev. 2005 Apr;16(2):179-86 [15863033.001]
  • [Cites] Cytokine Growth Factor Rev. 2005 Apr;16(2):233-47 [15863038.001]
  • [Cites] Mol Cell. 2005 Jul 22;19(2):159-70 [16039586.001]
  • [Cites] J Appl Toxicol. 2005 Sep-Oct;25(5):374-82 [16013042.001]
  • [Cites] Oncogene. 2006 Jan 5;25(1):43-50 [16278684.001]
  • [Cites] Oncologist. 2006 Jan;11(1):65-72 [16401715.001]
  • [Cites] J Biol Chem. 2006 Jun 9;281(23):15909-15 [16574643.001]
  • [Cites] J Pharmacol Exp Ther. 2006 Dec;319(3):991-7 [16801453.001]
  • [Cites] J Biol Chem. 2007 Jun 1;282(22):16502-10 [17403689.001]
  • [Cites] Int J Oncol. 2007 Sep;31(3):657-62 [17671694.001]
  • [Cites] Cancer Res. 2007 Aug 15;67(16):7756-64 [17699780.001]
  • [Cites] J Cell Physiol. 2004 Jun;199(3):371-80 [15095284.001]
  • [Cites] Trends Biochem Sci. 2004 Feb;29(2):95-102 [15102436.001]
  • [Cites] FASEB J. 2004 Jul;18(10):1162-4 [15132987.001]
  • [Cites] J Biol Chem. 2004 Sep 17;279(38):39317-30 [15247297.001]
  • [Cites] Mol Cell Biol. 1992 Mar;12(3):915-27 [1545823.001]
  • [Cites] Prog Growth Factor Res. 1992;4(2):107-20 [1299353.001]
  • [Cites] Oncogene. 1995 May 18;10(10):2027-35 [7761103.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8881-5 [7568036.001]
  • [Cites] EMBO J. 1997 Apr 15;16(8):1901-8 [9155016.001]
  • [Cites] Mol Cell Biol. 1999 Dec;19(12):8052-65 [10567531.001]
  • [Cites] Breast Cancer Res Treat. 1999 Jul;56(2):153-67 [10573108.001]
  • [Cites] J Biol Chem. 2000 Jan 21;275(3):1739-48 [10636870.001]
  • [Cites] J Cell Biol. 2000 Mar 20;148(6):1267-81 [10725339.001]
  • [Cites] J Biol Chem. 2000 Apr 21;275(16):12074-9 [10766840.001]
  • [Cites] Cancer Res. 2000 Nov 1;60(21):6160-70 [11085540.001]
  • [Cites] J Biol Chem. 2000 Dec 15;275(50):39435-43 [10993883.001]
  • [Cites] Science. 1998 May 22;280(5367):1262-5 [9596579.001]
  • [Cites] EMBO J. 1999 Feb 1;18(3):664-74 [9927426.001]
  • [Cites] J Neurochem. 1999 Feb;72(2):576-84 [9930729.001]
  • [Cites] Endocr Rev. 2001 Apr;22(2):153-83 [11294822.001]
  • (PMID = 18263590.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] ENG
  • [Grant] United States / NIAAA NIH HHS / AA / AA015407-03; United States / NIAAA NIH HHS / AA / R01 AA015407; United States / NIAAA NIH HHS / AA / AA 015407; United States / NIAAA NIH HHS / AA / R01 AA015407-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Multienzyme Complexes; 0 / Neoplasm Proteins; 0 / Oxidants; 0 / RNA, Small Interfering; 0 / Solvents; 103107-01-3 / Fibroblast Growth Factor 2; 3K9958V90M / Ethanol; BBX060AN9V / Hydrogen Peroxide; EC 2.7.11.1 / glycogen synthase kinase 3 beta; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 1; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 3; EC 2.7.11.26 / Glycogen Synthase Kinase 3
  • [Other-IDs] NLM/ PMC2431019
  •  go-up   go-down


9. Carvajal R, Meyers P: Ewing's sarcoma and primitive neuroectodermal family of tumors. Hematol Oncol Clin North Am; 2005 Jun;19(3):501-25, vi-vii
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ewing's sarcoma and primitive neuroectodermal family of tumors.
  • The Ewing's sarcoma family of tumors (EFT) includes ES of bone (ESB), extraosseous ES (EES), peripheral primitive neuroectodermal tumor of bone (pPNET), and malignant small-cell tumor of the thoracopulmonary region, or Askin's tumor, all of which are now known to be neoplasms of neuroectodermal origin.
  • [MeSH-major] Bone Neoplasms / pathology. Brain Neoplasms / pathology. Neuroectodermal Tumors, Primitive / pathology. Sarcoma, Ewing / pathology

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15939194.001).
  • [ISSN] 0889-8588
  • [Journal-full-title] Hematology/oncology clinics of North America
  • [ISO-abbreviation] Hematol. Oncol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 175
  •  go-up   go-down


10. Tazi I, Zafad S, Madani A, Harif M, Quessar A, Benchekroun S: [Askin tumor: a case report with literature review]. Cancer Radiother; 2009 Dec;13(8):771-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Askin tumor: a case report with literature review].
  • [Transliterated title] Tumeur d'Askin: à propos d'un cas avec revue de la littérature.
  • Askin tumor is a rare malignant tumor arising from soft tissues of the chest wall, rarely in the lung.
  • We report a case of Askin tumor in a 5-year-old child with reviewing the different data from the literature.
  • [MeSH-major] Neuroectodermal Tumors, Primitive / diagnosis. Thoracic Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19692278.001).
  • [ISSN] 1769-6658
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 27
  •  go-up   go-down


11. Kuroda N, Takahashi T, Moriki T, Okanoue Y, Mizobuchi H, Miyazaki E, Hayashi Y, Lee GH: Askin tumor with metastasis to the scalp: a histochemical, immunohistochemical and ultrastructural study. Med Mol Morphol; 2006 Dec;39(4):221-5
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Askin tumor with metastasis to the scalp: a histochemical, immunohistochemical and ultrastructural study.
  • A 29-year-old woman presented with facial edema, and imaging disclosed a tumor extending from the anterior chest wall to the anterosuperior aspect of the mediastinum.
  • Transbronchial cytology of the primary tumor and biopsy of the metastatic scalp lesion were performed.
  • Histologically, the tumor consisted of closely packed small round cells.
  • The neoplastic cells generally had round nuclei, finely dispersed chromatin, and small to prominent nucleoli.
  • Immunohistochemically, the neoplastic cell membranes reacted with CD99 (MIC2) and the neoplastic nuclei reacted with Fli-1, but various other markers, including lymphocyte and skeletal muscle markers, were not detected.
  • Even if results are immunohistochemically negative for neuroendocrine markers, the combination of immunohistochemistry of CD99 (MIC2) and Fil-1 may be useful in diagnosing Askin tumor or its metastatic lesion.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Bone Neoplasms / secondary. Neuroectodermal Tumors, Primitive, Peripheral / secondary. Scalp / pathology. Thoracic Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD / metabolism. Cell Adhesion Molecules / metabolism. Cell Nucleus / metabolism. Cell Nucleus / ultrastructure. Chromogranin A / metabolism. Female. Humans. Immunohistochemistry. Microscopy, Electron, Transmission. Proto-Oncogene Protein c-fli-1 / metabolism. Thoracic Wall / pathology

  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17187186.001).
  • [ISSN] 1860-1480
  • [Journal-full-title] Medical molecular morphology
  • [ISO-abbreviation] Med Mol Morphol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Chromogranin A; 0 / FLI1 protein, human; 0 / Proto-Oncogene Protein c-fli-1
  •  go-up   go-down


12. Mulsow J, Jeffers M, McDermott R, Geraghty J, Rothwell J: Complete clinical response to neoadjuvant chemotherapy in a 54-year-old male with Askin tumor. Thorac Cardiovasc Surg; 2010 Aug;58(5):306-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Complete clinical response to neoadjuvant chemotherapy in a 54-year-old male with Askin tumor.
  • Askin tumor is a tumor of the thoracopulmonary region that most commonly affects children and adolescents.
  • These rare tumors are a form of primitive neuroectodermal tumor and typically carry a poor prognosis.
  • Treatment is multimodal and consists of a combination of neoadjuvant chemotherapy, radical resection, and adjuvant chemo- and radiotherapy or all of the above.
  • We report a case of Askin tumor in a 54-year-old male who showed rapid and complete response to neoadjuvant chemotherapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Neuroectodermal Tumors, Primitive / drug therapy. Thoracic Neoplasms / drug therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) Georg Thieme Verlag KG Stuttgart-New York.
  • (PMID = 20680911.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


13. Nakajima Y, Koizumi K, Hirata T, Hirai K, Fukushima M, Yamagishi S, Kawashima T, Kinoshita H, Shimizu K: Long-term survival of Askin tumor for 10 years with 2 relapses. Ann Thorac Cardiovasc Surg; 2006 Apr;12(2):137-40
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term survival of Askin tumor for 10 years with 2 relapses.
  • An abnormal shadow was noted on a chest X-ray of a 32-year-old female in a medical check-up in March 1995, 3 months after she had given birth.
  • Thoracic CT detected a tumor in contact with the left thoracic wall, and tumorectomy was performed in May 1995.
  • The tumor was diagnosed as a primitive neuroectodermal tumor (PNET).
  • After surgery, the thoracic wall to which the tumor adhered was treated with irradiation at 50 Gy.
  • [MeSH-major] Lung Neoplasms / secondary. Neuroectodermal Tumors, Primitive / pathology. Sarcoma, Ewing / pathology. Thoracic Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16702938.001).
  • [ISSN] 1341-1098
  • [Journal-full-title] Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
  • [ISO-abbreviation] Ann Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


14. Peng RJ, Sun XF, Xiang XJ, Zhen ZJ, Ling JY, Tong GL, Xia Y, Xu GC, Jiang WQ: [Efficacy and survival of 92 cases of Ewing's sarcoma family of tumor initially treated with multidisciplinary therapy]. Ai Zheng; 2009 Dec;28(12):1304-9
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Efficacy and survival of 92 cases of Ewing's sarcoma family of tumor initially treated with multidisciplinary therapy].
  • BACKGROUND AND OBJECTIVE: Ewing's sarcoma family of tumor (ESFT) is aggressive.
  • RESULT: Of 92 cases, 23 were Ewing's sarcoma of bone, 21 extraosseous Ewing's sarcoma, 43 peripheral primitive neuroectodermal tumor, and 5 Askin tumor.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / drug therapy. Neuroectodermal Tumors, Primitive, Peripheral / drug therapy. Sarcoma, Ewing / drug therapy

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19958626.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; CAV protocol
  •  go-up   go-down


15. Katsenos S, Nikopoloulou M, Kokkonouzis I, Archondakis S: Askin's tumor: a rare chest wall neoplasm. Case report and short review. Thorac Cardiovasc Surg; 2008 Aug;56(5):308-10
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for askin's tumor .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Askin's tumor: a rare chest wall neoplasm. Case report and short review.
  • Askin's tumor is a rare neoplasm of the chest wall with a dismalprognosis.
  • Histopathology revealed an Askin's tumor infiltrating the 5th ipsilateral rib and pleura.
  • This is the first reported case of Askin's tumor in Greece and we focus on the clinical, radiological,pathological and therapeutic aspects of this rare entity.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18615383.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 7
  •  go-up   go-down


16. Mordant P, Le Pimpec-Barthes F, Riquet M: [Neurogenic tumors of the mediastinum in adults]. Rev Pneumol Clin; 2010 Feb;66(1):81-94

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Neurogenic tumors of the mediastinum in adults].
  • [Transliterated title] Tumeurs nerveuses du médiastin de l'adulte.
  • In adults, mediastinal neurogenic tumours constitute the third group of mediastinal tumours, after thymomas and lymphomas.
  • If the group of neurogenic tumour is frequent, each type of tumour is relatively unusual in everyday's clinic.
  • Among them, nerve sheath tumours are the more frequent, followed by tumour of the autonomic system.
  • Askin tumour remains uncommon.
  • Treatment of this tumour requires complete preoperative work-up, including standard radiography, CT-scan, MRI, and sometimes nuclear imaging.
  • In most cases, the treatment is based on surgical resection, and may be associated with radiotherapy or chemotherapy in case of malignant tumour or incomplete resection.
  • Better understanding of these tumours, including their molecular abnormalities, may lead to new changes in their classifications, and to their management.
  • [MeSH-major] Ganglia, Autonomic. Ganglioneuroblastoma / surgery. Ganglioneuroma / surgery. Mediastinal Neoplasms / surgery. Nerve Sheath Neoplasms / surgery. Paraganglioma / surgery. Peripheral Nervous System Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20207300.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 64
  •  go-up   go-down


17. Cherecheş-Panţa P, Gocan H, Fufezan O, Gheban D, Nanulescu MV: [Askin tumor. Consideration on a case]. Pneumologia; 2006 Jan-Mar;55(1):32-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Askin tumor. Consideration on a case].
  • [Transliterated title] Tumora askin. Consideraţii pe marginea unui caz.
  • The authors present the case of a male patient of 9 years of age admitted for thoracic pain.
  • The clinical evaluation and the imaging exams (chest X-ray, ultrasonography exam of the chest and thoracic computer tomography) reveal a tumor of the thoracic wall.
  • At the pathological exam the tumor presented an aspect of Askin tumor.
  • The authors discuss the theoretical aspects correlated with the diagnosis of Askin tumor, based on the presented case.
  • [MeSH-major] Neuroectodermal Tumors, Primitive, Peripheral / diagnosis. Neuroectodermal Tumors, Primitive, Peripheral / surgery. Thoracic Neoplasms / diagnosis. Thoracic Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17069216.001).
  • [ISSN] 2067-2993
  • [Journal-full-title] Pneumologia (Bucharest, Romania)
  • [ISO-abbreviation] Pneumologia
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
  •  go-up   go-down


18. Thacker MM, Temple HT, Scully SP: Current treatment for Ewing's sarcoma. Expert Rev Anticancer Ther; 2005 Apr;5(2):319-31
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ewing's sarcoma is the second most common primary bone tumor seen in children and adolescents, and was described by James Ewing in 1921 as a diffuse endothelioma of bone.
  • It is one of the differential diagnoses of pediatric small round blue cell tumors.
  • This is not a single condition, but a group of morphologically and clinically closely related disorders with similar molecular biology -- expression of tumor-specific chimeric oncoproteins through balanced chromosomal translocations involving the EWS gene -- often referred to as the Ewing family of tumors.
  • This includes Ewing's sarcoma of bone, extra-osseous Ewing's sarcoma, Askin tumor and peripheral neuroectodermal tumor.
  • An aggressive multidisciplinary approach has resulted in significant improvement in prognosis for patients with these tumors.
  • Advances in understanding the molecular biology of these tumors will hopefully result in the development of novel treatment approaches.

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15877528.001).
  • [ISSN] 1744-8328
  • [Journal-full-title] Expert review of anticancer therapy
  • [ISO-abbreviation] Expert Rev Anticancer Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 123
  •  go-up   go-down


19. Seddon BM, Whelan JS: Emerging chemotherapeutic strategies and the role of treatment stratification in Ewing sarcoma. Paediatr Drugs; 2008;10(2):93-105
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The Ewing sarcoma family of tumors (ESFT) is one of the most common groups of malignancies arising in children, adolescents, and young adults up to approximately 25 years of age.
  • It comprises Ewing sarcoma arising from bone and extraosseous Ewing sarcoma arising from soft tissues (which includes peripheral neuroectodermal tumors and Askin tumor arising from the chest wall).
  • These can be categorized as tumor-related factors (presence of metastases, tumor site, volume, lactic dehydrogenase level, chromosomal translocation type, presence of fusion transcripts in blood and bone marrow), treatment-related factors (local therapy, histologic response to chemotherapy, radiologic response to chemotherapy, chemotherapy regimen), and patient-related factors (gender, age).
  • [MeSH-minor] Age Factors. Antineoplastic Protocols. Combined Modality Therapy. Humans. Pediatrics. Prognosis. Protein Kinases / physiology. Receptor, IGF Type 1 / physiology. Signal Transduction. TOR Serine-Threonine Kinases

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18345719.001).
  • [ISSN] 1174-5878
  • [Journal-full-title] Paediatric drugs
  • [ISO-abbreviation] Paediatr Drugs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] New Zealand
  • [Chemical-registry-number] EC 2.7.- / Protein Kinases; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.10.1 / Receptor, IGF Type 1
  • [Number-of-references] 126
  •  go-up   go-down


20. Subbiah V, Anderson P, Lazar AJ, Burdett E, Raymond K, Ludwig JA: Ewing's sarcoma: standard and experimental treatment options. Curr Treat Options Oncol; 2009 Apr;10(1-2):126-40
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OPINION STATEMENT: Ewing sarcoma family tumors (EWS), which include classic Ewing's sarcoma in addition to primitive neuroectodermal tumor and Askin tumor, are the second most common variety of primary bone cancer to afflict adolescents and young adults.
  • As has already occurred for malignancies such as breast or colon cancer, the "-omics-based" revolution has enhanced our understanding of the molecular changes responsible for Ewing's tumor formation and identified a number of potential targets (such as IGF-1R or mTOR) amenable to biological therapy.

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19533369.001).
  • [ISSN] 1534-6277
  • [Journal-full-title] Current treatment options in oncology
  • [ISO-abbreviation] Curr Treat Options Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / EWS-FLI fusion protein; 0 / Oncogene Proteins, Fusion; 0 / Proto-Oncogene Protein c-fli-1; 0 / RNA-Binding Protein EWS; 0 / Transcription Factors; EC 2.7.10.1 / Receptor, IGF Type 1
  • [Number-of-references] 94
  •  go-up   go-down


21. Lahl M, Fisher VL, Laschinger K: Ewing's sarcoma family of tumors: an overview from diagnosis to survivorship. Clin J Oncol Nurs; 2008 Feb;12(1):89-97
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ewing's sarcoma family of tumors: an overview from diagnosis to survivorship.
  • The Ewing's sarcoma family of tumors (ESFT) is a malignant primary bone tumor often involving soft tissue that affects not only children but also young adults.
  • Since 1992, with the addition of ifosfamide and etoposide to standard chemotherapy for primary tumors, much improvement has been made in the treatment of ESFT, with a primary focus on children.
  • ESFT, which includes Ewing's sarcoma, extraosseous Ewing's sarcoma, Askin tumor, and primitive neuroectodermal tumor, is the second most common primary malignant bone tumor in children and adolescents.
  • It accounts for 10% of primary malignant bone tumors in children and 3% of all childhood malignancies.
  • Treatment for ESFT consists of a multimodal approach, including chemotherapy, radiation therapy, and surgery.
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Combined Modality Therapy / adverse effects. Combined Modality Therapy / nursing. Humans. Incidence. Nurse's Role. Oncology Nursing / organization & administration. Prognosis. Radiotherapy, Adjuvant. Risk Factors. Stem Cell Transplantation. Survival Rate. Treatment Outcome

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18258578.001).
  • [ISSN] 1092-1095
  • [Journal-full-title] Clinical journal of oncology nursing
  • [ISO-abbreviation] Clin J Oncol Nurs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 25
  •  go-up   go-down


22. Barisella M, Collini P, Orsenigo M, Aiello A, Paties CT, Dileo P, Pilotti S: Unusual myogenic and melanocytic differentiation of soft tissue pPNETs: an immunohistochemical and molecular study of 3 cases. Am J Surg Pathol; 2010 Jul;34(7):1002-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All of the members of the peripheral primitive neuroectodermal tumor family (Ewing sarcomas, neuroectodermal tumors of bone, peripheral neuroepitheliomas, and Askin tumors) have similar morphologic and immunophenotypical features (ie, the proliferation of small and medium-sized round cells in a fibrous background showing strong and diffuse immunohistochemical positivity for CD99), and the common cytogenetic abnormality of a nonrandom translocation involving the EWS gene and one of several members of the erythroblastosis virus transforming sequence family of transcription factors.
  • The combination of clinical information and morphologic/immunophenotypical characteristics is usually sufficient for a correct diagnosis, but there are rare cases in which an unusual predominant or multidirectional immunophenotypical differentiation makes diagnosis a challenge and requires the use of molecular cytogenetic or molecular techniques.
  • [MeSH-major] Cell Transformation, Neoplastic. Melanocytes / pathology. Muscle Cells / pathology. Neuroectodermal Tumors, Primitive, Peripheral / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor. Cell Proliferation. DNA, Neoplasm / analysis. Desmin / analysis. Gene Expression. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Male. Oncogene Proteins, Fusion / analysis. Oncogene Proteins, Fusion / genetics. Proto-Oncogene Protein c-fli-1 / analysis. Proto-Oncogene Protein c-fli-1 / genetics. RNA, Messenger / metabolism. RNA-Binding Protein EWS / analysis. RNA-Binding Protein EWS / genetics. Translocation, Genetic

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Am J Surg Pathol. 2011 Mar;35(3):464; author reply 464-5 [21297440.001]
  • (PMID = 20495444.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Desmin; 0 / EWS-FLI fusion protein; 0 / Oncogene Proteins, Fusion; 0 / Proto-Oncogene Protein c-fli-1; 0 / RNA, Messenger; 0 / RNA-Binding Protein EWS
  •  go-up   go-down


23. Soyer T, Karnak I, Ciftci AO, Senocak ME, Tanyel FC, Büyükpamukçu N: The results of surgical treatment of chest wall tumors in childhood. Pediatr Surg Int; 2006 Feb;22(2):135-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The results of surgical treatment of chest wall tumors in childhood.
  • Chest wall tumors (CWT) are rarely seen in childhood and surgery constitutes a complementary part of the therapy.
  • The diagnosis was malignant tumor in 12 (70%) and benign in 5 (30%).
  • They were Ewing's sarcoma (ES) (n = 4), primitive neuroectodermal tumor (PNET) (n = 3), Askin's tumor (n = 1), rhabdomyosarcoma (RMS) (n = 2), neuroblastoma (n = 2), osteochondroma (n = 1), aneurysmal bone cyst (n = 2) and hamartoma (n = 2).
  • Preoperative chemotherapy was given to most patients with malignant tumor.
  • All patients had only local tumor at the time of resection.
  • All tumor tissues with the affected rib/ribs were resected en bloc with the adjacent tissues.
  • Patients with benign tumor were free of complaints or complications during follow up.
  • All patients with malignant tumor received postoperative chemotherapy.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16328338.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


24. Sunil I, Bond SJ, Nagaraj HS: Primitive neuroectodermal tumor of the sternum in a child: resection and reconstruction. J Pediatr Surg; 2006 Nov;41(11):e5-8
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primitive neuroectodermal tumor of the sternum in a child: resection and reconstruction.
  • They represent less than 1% of all bone tumors.
  • Primitive neuroectodermal tumor of the chest wall or Askin's tumor is more often seen in the ribs than in the sternum.
  • Surgical treatment involves resection of the tumor followed by primary reconstruction.
  • We report the case of a 16-year-old adolescent boy who was diagnosed to have primitive neuroectodermal tumor of the sternum and underwent resection with primary reconstruction of the anterior chest wall.
  • We describe for the first time the use of a 2-mm Gore-Tex Dualmesh plus biomaterial (W.L.
  • [MeSH-major] Bone Neoplasms / surgery. Neuroectodermal Tumors, Primitive / surgery. Orthopedic Procedures / methods. Sternum / surgery

  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17101344.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biocompatible Materials; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; CAV protocol
  •  go-up   go-down


25. Karatas Silistreli O, Ayhan M, Görgü M, Oztan Y, Sisman N: A primitive neuroectodermal tumor on the face: case report. Acta Chir Plast; 2005;47(2):38-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A primitive neuroectodermal tumor on the face: case report.
  • In 1918, Stout defined the lesion in which small round cells originating from the ulnar nerve formed a rosette as neuroepithelioma.
  • It was claimed that this tumor originated from neuroectodermis and was different from the classical neuroblastoma.
  • The term primitive neuroectodermal tumor (PNET) involves a group of tumors of the soft tissue originating from neural crest and resulting from the brain, spinal cord and branches of the sympathetic nervous system.
  • Extracranial primitive neuroectodermal tumors originate from neural crest cells outside the sympathetic and central nervous system.
  • PNET also has some distinctive histological, immunohistochemical and ultrastructural features.
  • It is usually encountered in children and young adults; most frequently located in thoracopulmonary region (Askin's tumor).
  • PNET is an aggressive tumor.
  • In this report, we presented a case of PNET located on the right cheek with multiple distant metastases.
  • Clinicians should be on alert when treating facial tumors, not to skip PNET, which is a very aggressive one.
  • [MeSH-major] Facial Neoplasms / surgery. Neuroectodermal Tumors / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16033149.001).
  • [ISSN] 0001-5423
  • [Journal-full-title] Acta chirurgiae plasticae
  • [ISO-abbreviation] Acta Chir Plast
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Czech Republic
  •  go-up   go-down


26. Jamema SV, Sharma PK, Laskar S, Deshpande DD, Shrivastava SK: Treatment planning comparison of electron arc therapy and photon intensity modulated radiotherapy for Askin's tumor of chest wall. Radiother Oncol; 2007 Sep;84(3):257-65

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment planning comparison of electron arc therapy and photon intensity modulated radiotherapy for Askin's tumor of chest wall.
  • BACKGROUND AND PURPOSE: A dosimetric study to quantitatively compare radiotherapy treatment plans for Askin's tumor using Electron Arc (EA) vs. photon Intensity Modulated Radiotherapy (IMRT).
  • [MeSH-major] Neuroectodermal Tumors, Primitive / radiotherapy. Radiotherapy Planning, Computer-Assisted. Radiotherapy, High-Energy. Radiotherapy, Intensity-Modulated. Sarcoma, Small Cell / radiotherapy. Thoracic Neoplasms / radiotherapy. Thoracic Wall

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17719111.001).
  • [ISSN] 0167-8140
  • [Journal-full-title] Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • [ISO-abbreviation] Radiother Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Ireland
  •  go-up   go-down


27. Miron I, Miron L, Dumitraş S, Aprodu G, Ciobanu A, Tansanu I: [Statistical study of the evolution over ten years of the clinical and therapeutic approach in childhood soft tissue sarcoma]. Rev Med Chir Soc Med Nat Iasi; 2007 Apr-Jun;111(2):358-62
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Studiul statistic clinico-terapeutic si evolutiv pe 10 ani in sarcoamele de tesuturi moi la copii si tineri.
  • Rhabdomyosarcoma (RMS) constitutes 5.8% from the whole amount of pediatric solid tumors, taking the fourth place after CNS tumors, neuroblastoma, and Wilms tumors.
  • The other category of non-rhabdomyosarcoma tumors in children and teenagers represents 3% of the solid malignancies under 18 years old.
  • We included in the study a well-known category of soft tissue tumors called of uncertain malignancy.
  • Maria" Clinical Emergency Hospital Iaşi on a group of 58 de patients ranging between 0 and 18 years old.
  • Based on histological examination 19 cases (32.75%) were of rhabdomyosarcoma type with following subtypes: alveolar--7 patients, embryonic-- 9 cases, fusiform - 2 cases, bothrioid--1 case), 8 cases were undifferentiated soft tissue sarcomas and one patient had a tumor of pleiomorphic type; 13 children (22.41%) had non-rhabdomyosarcoma soft tissue sarcomas: 6 fibrosarcomas, 2 synovial sarcomas, 1 leiomyosarcoma, 1 Kaposi sarcoma, 1 case of malignant peripheral nerve sheath tumor, 1 case of angioma tumor, one liposarcoma; 16 cases were included in soft tissue tumors of uncertain origin (fibromatosis--6 cases, fibrous histiocytoma--4 cases, hamartoma--cases, myoblastoma--1 case, fibro-xanthoma--1 case, hemangioendothelioma--1 case); 1 PPNET (Askin tumor).
  • CONCLUSIONS: The continuously augmented incidence of soft tissue sarcoma in young ages and the advanced stages initial presentations of tumors require a much more serious and rhythmic survey at general practitioner level.

  • Genetic Alliance. consumer health - Soft tissue sarcoma.
  • Genetic Alliance. consumer health - TEN.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17983168.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] rum
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Romania
  •  go-up   go-down


28. Papi A, Ferreri AM, Rocchi P, Guerra F, Orlandi M: Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells. Anticancer Res; 2010 Feb;30(2):535-40
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells.
  • In this study, the anticancer properties of VPA on neural crest-derived human tumor cell lines G361 melanoma, U87MG glioblastoma and SKNMC Askin tumor cells were investigated.
  • The effect of VPA on cell growth, apoptotic activity and invasive ability were evaluated.
  • Firstly, VPA induced cell growth inhibition and apoptotic activity, as demonstrated by sulforhodamine B protein assay, annexin V assay and by Western blot analysis for Bcl2 and Bax expression levels, in all three cell lines.
  • Treatment with VPA caused a decrease in the invasive ability of all three cell lines.
  • Taken together, our results, besides providing further evidence that VPA may represent a promising therapeutic strategy in cancer treatment, may help in the design of new protocols geared at the treatment of neural crest-derived tumors.
  • [MeSH-minor] Apoptosis / drug effects. Blotting, Western. Cell Line, Tumor. Cell Proliferation / drug effects. Humans. Matrix Metalloproteinases / metabolism. Neoplasm Invasiveness. Tissue Inhibitor of Metalloproteinase-1 / metabolism

  • Genetic Alliance. consumer health - Neural crest tumor.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. VALPROIC ACID .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20332466.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Tissue Inhibitor of Metalloproteinase-1; 614OI1Z5WI / Valproic Acid; EC 3.4.24.- / Matrix Metalloproteinases
  •  go-up   go-down


29. Iwamoto Y: Diagnosis and treatment of Ewing's sarcoma. Jpn J Clin Oncol; 2007 Feb;37(2):79-89
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ewing's sarcoma is a small round-cell tumor typically arising in the bones, rarely in soft tissues, of children and adolescents.
  • Ewing's sarcoma has retained the most unfavorable prognosis of all primary musculoskeletal tumors.
  • In addition, the preferred method of tumor resection has changed; limb salvage has nearly replaced amputation of the affected limb.
  • Recent studies have revealed that the pathognomonic translocations involving the EWS gene on chromosome 22 and an ETS-type gene, which is most commonly the Fli1 gene on chromosome 11, are implicated in more than 95% of Ewing's sarcomas, primitive neuroectodermal tumors and Askin's tumors.
  • Therefore, these lesions have become regarded as a single entity, dubbed the Ewing's family of tumors.
  • RT-PCR to detect EWS-ETS gene arrangements is widely used to confirm the diagnosis of Ewing's family of tumors.

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17272319.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 61
  •  go-up   go-down


30. Rafailidis S, Ballas K, Psarras K, Pavlidis T, Symeonidis N, Marakis G, Sakadamis A: Primary Ewing sarcoma of the stomach--a newly described entity. Eur Surg Res; 2009;42(1):17-20
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The Ewing sarcoma family of tumors (ESFT) includes classic Ewing sarcoma of the bone, extraosseous or soft tissue Ewing sarcoma, Askin tumors of the chest wall, and peripheral primitive neuroectodermal tumors of the bone and soft tissues.
  • They share a common neural histogenesis, tumor genetics and biology.
  • The genetic hallmark of the ESFT is the presence of t(11;22)(q24;q12), which creates the EWS/FLI1 fusion gene and results in the expression of a chimeric protein.
  • Although Ewing tumors can occur at any age, the great majority are found in individuals less than 20 years of age.
  • [MeSH-minor] Aged. Antigens, CD / metabolism. Cell Adhesion Molecules / metabolism. Chromosomes, Human, Pair 11 / genetics. Chromosomes, Human, Pair 22 / genetics. Humans. Male. Oncogene Proteins, Fusion / genetics. Proto-Oncogene Protein c-fli-1 / genetics. RNA-Binding Protein EWS. Translocation, Genetic

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2008 S. Karger AG, Basel.
  • (PMID = 18971581.001).
  • [ISSN] 1421-9921
  • [Journal-full-title] European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes
  • [ISO-abbreviation] Eur Surg Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / EWS-FLI fusion protein; 0 / Oncogene Proteins, Fusion; 0 / Proto-Oncogene Protein c-fli-1; 0 / RNA-Binding Protein EWS
  •  go-up   go-down


31. Lee KM, Wah HK: Primary Ewing's sarcoma family of tumors arising from the broad ligament. Int J Gynecol Pathol; 2005 Oct;24(4):377-81
Genetic Alliance. consumer health - Ewing's Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary Ewing's sarcoma family of tumors arising from the broad ligament.
  • We report a case of a primary Ewing's sarcoma family of tumors (ESFT) that was an incidental finding in the broad ligament of a 53-year-old woman.
  • ESFT now includes tumors previously described as Askin tumor, neuroepithelioma, extraskeletal Ewing's sarcoma, and peripheral primitive neuroectodermal tumor.
  • This is because of the discovery that all of the above tumors contain a specific gene rearrangement involving chromosome 22q12.
  • On microscopic examination, the tumor was composed of small, round cells with mild nuclear pleomorphism and scant eosinophilic cytoplasm.
  • There were large areas of tumor necrosis and numerous mitoses.
  • Fluorescence in situ hybridization revealed a separation of the breakapart probe on chromosome 22q12 consistent with the presence of a gene rearrangement, supporting the diagnosis of ESFT.
  • We believe the importance of recognizing the existence of a primary ESFT in the broad ligament as some primary tumors of the gynecological tract and of other systems may resemble it histologically.
  • [MeSH-minor] Antigens, CD / analysis. Antigens, CD56 / analysis. Cell Adhesion Molecules / analysis. Female. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Middle Aged. Phosphopyruvate Hydratase / analysis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16175085.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD56; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; EC 4.2.1.11 / Phosphopyruvate Hydratase
  •  go-up   go-down


32. Chandran SR, Rojith KB, Ramkumar N, Veerakesari S, Nedumaran, Umakanthan K: Askin's tumor. J Assoc Physicians India; 2009 May;57:393
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Askin's tumor.
  • [MeSH-major] Bone Neoplasms / radiography. Neuroectodermal Tumors, Primitive, Peripheral / radiography. Ribs / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19634286.001).
  • [ISSN] 0004-5772
  • [Journal-full-title] The Journal of the Association of Physicians of India
  • [ISO-abbreviation] J Assoc Physicians India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down






Advertisement