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1. Borm GF, Lemmers O, Fransen J, Donders R: The evidence provided by a single trial is less reliable than its statistical analysis suggests. J Clin Epidemiol; 2009 Jul;62(7):711-715.e1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Antirheumatic Agents / therapeutic use. Arthritis, Rheumatoid / drug therapy. Data Interpretation, Statistical. Electromagnetic Fields / adverse effects. Humans. Leukemia, Radiation-Induced / epidemiology. Leukemia, Radiation-Induced / etiology. Outcome Assessment (Health Care) / methods. Patient Selection. Research Design

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  • [CommentIn] J Clin Epidemiol. 2009 Aug;62(8):886-7; author reply 887-9 [19481419.001]
  • (PMID = 19171462.001).
  • [ISSN] 1878-5921
  • [Journal-full-title] Journal of clinical epidemiology
  • [ISO-abbreviation] J Clin Epidemiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antirheumatic Agents
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2. Catera R, Silverman GJ, Hatzi K, Seiler T, Didier S, Zhang L, Hervé M, Meffre E, Oscier DG, Vlassara H, Scofield RH, Chen Y, Allen SL, Kolitz J, Rai KR, Chu CC, Chiorazzi N: Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation. Mol Med; 2008 Nov-Dec;14(11-12):665-74
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  • [Title] Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation.
  • Chronic lymphocytic leukemia (CLL) represents the outgrowth of a CD5(+) B cell.
  • Its etiology is unknown.

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  • (PMID = 19009014.001).
  • [ISSN] 1528-3658
  • [Journal-full-title] Molecular medicine (Cambridge, Mass.)
  • [ISO-abbreviation] Mol. Med.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / M01 RR018535; United States / NCI NIH HHS / CA / R01 CA087956; United States / NCI NIH HHS / CA / CA87956; United States / NCRR NIH HHS / RR / RR018535
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Autoantigens; 0 / Epitopes
  • [Other-IDs] NLM/ PMC2582860
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3. Gupta D, Singh S, Suri D, Ahluwalia J, Das R, Varma N: Arthritic presentation of acute leukemia in children: experience from a tertiary care centre in North India. Rheumatol Int; 2010 Apr;30(6):767-70
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  • [Title] Arthritic presentation of acute leukemia in children: experience from a tertiary care centre in North India.
  • The objectives of this study are to highlight the arthritic presentation of acute lymphoblastic leukemia (ALL) in children and to delineate features that could help differentiate it from juvenile idiopathic arthritis (JIA).
  • [MeSH-major] Arthritis / diagnosis. Arthritis / etiology. Arthritis, Juvenile / diagnosis. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications. Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • [MeSH-minor] Anemia / etiology. Anemia / physiopathology. Arthralgia / etiology. Arthralgia / physiopathology. Biomarkers / analysis. Bone Marrow Examination / standards. Case-Control Studies. Child. Child, Preschool. Diagnosis, Differential. Diagnostic Errors / prevention & control. Female. Humans. India. Leukopenia / etiology. Leukopenia / physiopathology. Lymphatic Diseases / etiology. Lymphocyte Count. Lymphocytes / pathology. Male. Pain / etiology. Pain / physiopathology. Pain Measurement. Splenomegaly / etiology. Thrombocytopenia / etiology

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  • [Journal-full-title] Rheumatology international
  • [ISO-abbreviation] Rheumatol. Int.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers
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4. Deng XL, Liu XY, Xu N: Comparative study on low back pain misdiagnosed as spondyloarthropathy. Clin Rheumatol; 2009 Aug;28(8):893-8
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  • The final diagnoses of these 24 cases were listed below: four malignant tumors (retroperitoneal adipose sarcoma, advanced gastric carcinoma, ovarian papillary epithelioma, acute lymphocytic leukemia), six benign tumors (two parathyroid adenoma with hyperparathyroidism, one intraspinal lipoma, intraspinal ependymomas, sacral tubulocyst, and intraspinal schwannoglioma, respectively).
  • [MeSH-major] Diagnostic Errors. Low Back Pain / etiology. Neoplasms / diagnosis. Severity of Illness Index. Spondylarthropathies / complications. Spondylarthropathies / diagnosis
  • [MeSH-minor] Adolescent. Adult. Diagnosis, Differential. Female. HLA-B27 Antigen / analysis. Humans. Male. Medical Audit. Middle Aged. Pain, Referred / etiology. Young Adult

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  • [Journal-full-title] Clinical rheumatology
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  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
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5. Pneumaticos SG, Chatziioannou SN, Savvidou C, Pilichou A, Rontogianni D, Korres DS: Routine needle biopsy during vertebral augmentation procedures. Is it necessary? Eur Spine J; 2010 Nov;19(11):1894-8
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  • The purpose of this study was to determine the frequency of underlying previously unrecognized etiology in a consecutive series of patients undergoing kyphoplasty to treat vertebral compression fractures.
  • In 11 patients underlying pathology other than osteoporosis was identified (prostate cancer, 1; pancreatic cancer, 1; colon cancer, 1; breast cancer, 2; multiple myeloma, 3; leukemia, 1; and lung cancer, 2).
  • In augmentation procedures for vertebral compression fractures, bone biopsy should be reserved for the patients where the preoperative evaluation raises the suspicion of a non-osteoporotic etiology.

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  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
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6. Kristinsson SY, Goldin LR, Björkholm M, Koshiol J, Turesson I, Landgren O: Genetic and immune-related factors in the pathogenesis of lymphoproliferative and plasma cell malignancies. Haematologica; 2009 Nov;94(11):1581-9
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  • [Title] Genetic and immune-related factors in the pathogenesis of lymphoproliferative and plasma cell malignancies.
  • There are data to support a role for genetic and immune-related factors in the pathogenesis of lymphomas and plasma cell diseases.
  • In this paper, we review our published large population-based studies and other relevant studies in Hodgkin's and non-Hodgkin's lymphomas, multiple myeloma, and the precursor condition monoclonal gammopathy of undetermined significance.
  • We discuss the overlap in risk factors between related malignancies and explore the underlying mechanisms.
  • Based on these studies, we provide clinical implications and discuss the relevance of these data for patient counseling and clinical follow-up.
  • Finally, we suggest future directions for new studies designed to increase our current knowledge and to define underlying biological mechanisms of our findings.

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  • (PMID = 19586941.001).
  • [ISSN] 1592-8721
  • [Journal-full-title] Haematologica
  • [ISO-abbreviation] Haematologica
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Italy
  • [Number-of-references] 93
  • [Other-IDs] NLM/ PMC2770969
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7. Poiraud C, Gagey-Caron V, Barbarot S, Durant C, Ayari S, Stalder JF: [Cutaneous, mucosal and systemic pyoderma gangrenosum]. Ann Dermatol Venereol; 2010 Mar;137(3):212-5
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  • CASE REPORT: A 56-year-old man was hospitalised for an inflammatory abdominal plaque with an ulcerated centre that appeared rapidly in a setting of fever of 40 degrees C, odynophagia, weight loss and arthritis of the ankle.
  • [MeSH-major] Leukemia, Myeloid, Acute / diagnosis. Mouth Mucosa / pathology. Pyoderma Gangrenosum / pathology
  • [MeSH-minor] Fever / etiology. Humans. Male. Middle Aged. Mouth Diseases / etiology

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20227565.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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8. Tafaghodi F, Aghighi Y, Rokni Yazdi H, Shakiba M, Adibi A: Predictive plain X-ray findings in distinguishing early stage acute lymphoblastic leukemia from juvenile idiopathic arthritis. Clin Rheumatol; 2009 Nov;28(11):1253-8
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  • [Title] Predictive plain X-ray findings in distinguishing early stage acute lymphoblastic leukemia from juvenile idiopathic arthritis.
  • Acute lymphoblastic leukemia (ALL) presenting with musculoskeletal pain may be difficult to distinguish from juvenile idiopathic arthritis (JIA).
  • [MeSH-major] Arthritis, Juvenile / diagnostic imaging. Arthrography / methods. Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnostic imaging
  • [MeSH-minor] Adolescent. Bone Diseases, Metabolic / diagnostic imaging. Bone Diseases, Metabolic / etiology. Bone and Bones / diagnostic imaging. Bone and Bones / pathology. Child. Child, Preschool. Diagnosis, Differential. Edema / diagnostic imaging. Edema / etiology. Female. Humans. Joints / pathology. Male


9. Singh M, Cowell L, Seo S, O'Neill G, Golemis E: Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle. Cell Biochem Biophys; 2007;48(1):54-72
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  • [Title] Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle.
  • Upregulation of the scaffolding protein HEF1, also known as NEDD9 and Cas-L, has recently been identified as a pro-metastatic stimulus in a number of different solid tumors, and has also been strongly associated with pathogenesis of BCR-Abl-dependent tumors.
  • As the evidence mounts for HEF1/NEDD9/Cas-L as a key player in metastatic cancer, it is timely to review the molecular regulation of HEF1/NEDD9/Cas-L.
  • Most of the mortality associated with cancer arises from uncontrolled metastases, thus a better understanding of the properties of proteins specifically associated with promotion of this process may yield insights that improve cancer diagnosis and treatment.
  • In this review, we summarize the extensive literature regarding HEF1/NEDD9/Cas-L expression and function in signaling relevant to cell attachment, migration, invasion, cell cycle, apoptosis, and oncogenic signal transduction.
  • The complex function of HEF1/NEDD9/Cas-L revealed by this analysis leads us to propose a model in which alleviation of cell cycle checkpoints and acquired resistance to apoptosis is permissive for a HEF1/NEDD9/Cas-L-promoted pro-metastatic phenotype.

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  • (PMID = 17703068.001).
  • [ISSN] 1085-9195
  • [Journal-full-title] Cell biochemistry and biophysics
  • [ISO-abbreviation] Cell Biochem. Biophys.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA 06927; United States / NCI NIH HHS / CA / R01 CA063366; United States / NCI NIH HHS / CA / R01 CA 63366; United States / NCI NIH HHS / CA / P30 CA006927; United States / NCI NIH HHS / CA / R01 CA063366-12; United States / NCI NIH HHS / CA / CA063366-12
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Integrins; 0 / NEDD9 protein, human; 0 / Phosphoproteins; EC 2.7.10.2 / Fusion Proteins, bcr-abl
  • [Number-of-references] 130
  • [Other-IDs] NLM/ NIHMS23302; NLM/ PMC1976382
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10. Gao Y, Kristinsson SY, Goldin LR, Björkholm M, Caporaso NE, Landgren O: Increased risk for non-Hodgkin lymphoma in individuals with celiac disease and a potential familial association. Gastroenterology; 2009 Jan;136(1):91-8
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  • METHODS: We identified 37,869 NHL, 8323 Hodgkin lymphoma (HL), and 13,842 chronic lymphocytic leukemia patients diagnosed in Sweden between 1965 and 2004, as well as 236,408 matched controls and 613,961 first-degree relatives.
  • Risk of HL was borderline increased (OR=2.54, 95% CI, 0.99-6.56); however, there was no excess chronic lymphocytic leukemia risk.
  • [MeSH-major] Celiac Disease / complications. Celiac Disease / genetics. Lymphoma, Non-Hodgkin / etiology
  • [MeSH-minor] Adult. Aged. Female. Humans. Leukemia, Lymphocytic, Chronic, B-Cell / etiology. Male. Middle Aged. Risk


11. Wlodarski MW, Nearman Z, Jankowska A, Babel N, Powers J, Leahy P, Volk HD, Maciejewski JP: Phenotypic differences between healthy effector CTL and leukemic LGL cells support the notion of antigen-triggered clonal transformation in T-LGL leukemia. J Leukoc Biol; 2008 Mar;83(3):589-601
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  • [Title] Phenotypic differences between healthy effector CTL and leukemic LGL cells support the notion of antigen-triggered clonal transformation in T-LGL leukemia.
  • T cell large granular lymphocyte leukemia (T-LGL) is a chronic clonal lymphoproliferation of CTL.
  • Here, we focus our analysis on immunological networks, as immune mechanisms play a prominent role in the etiology of bone marrow failure in T-LGL.
  • Despite a strikingly similar gene expression profile between T-LGL clones and their healthy counterparts, important phenotypic differences were identified, including up-modulation of TNFRS9, myeloid cell leukemia sequence 1, IFN-gamma, and IFN-gamma-related genes, and several integrins/adhesion molecules.

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  • (PMID = 18086899.001).
  • [ISSN] 0741-5400
  • [Journal-full-title] Journal of leukocyte biology
  • [ISO-abbreviation] J. Leukoc. Biol.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / HL073429-01A1; United States / NHLBI NIH HHS / HL / R01 HL073429; United States / NHLBI NIH HHS / HL / R01 HL 073429-01A1; United States / NHLBI NIH HHS / HL / R01 HL073429-01A1
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Neoplasm Proteins
  • [Other-IDs] NLM/ NIHMS83527; NLM/ PMC2629660
  •  go-up   go-down


12. Daoussis D, Liossis SN, Tsamandas AC, Kalogeropoulou C, Kazantzi A, Sirinian C, Karampetsou M, Yiannopoulos G, Andonopoulos AP: Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study. Rheumatology (Oxford); 2010 Feb;49(2):271-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Aged. B-Lymphocytes / drug effects. Biopsy. Cell Adhesion Molecules / metabolism. Collagen / metabolism. Drug Administration Schedule. Humans. Lung Diseases, Interstitial / drug therapy. Lung Diseases, Interstitial / etiology. Lung Diseases, Interstitial / physiopathology. Lymphocyte Depletion / methods. Middle Aged. Respiratory Function Tests / methods. Rituximab. Skin / immunology. Skin / metabolism. Skin / pathology. Tomography, X-Ray Computed. Vital Capacity / drug effects

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  • [CommentIn] Rheumatology (Oxford). 2010 Feb;49(2):201-2 [20032221.001]
  • (PMID = 19447770.001).
  • [ISSN] 1462-0332
  • [Journal-full-title] Rheumatology (Oxford, England)
  • [ISO-abbreviation] Rheumatology (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Cell Adhesion Molecules; 0 / Immunosuppressive Agents; 4F4X42SYQ6 / Rituximab; 9007-34-5 / Collagen
  • [Other-IDs] NLM/ PMC2806066
  •  go-up   go-down


13. Shishido-Hara Y: Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating disease. Acta Neuropathol; 2010 Sep;120(3):403-17
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  • [Title] Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating disease.
  • Recently, promyelocytic leukemia nuclear bodies (PML-NBs), punctuate structures for important nuclear functions in eukaryotic cells, were identified as an intranuclear target of JC virus infection.
  • Here, we review what we have learned since the disease entity establishment, including a look at recent progress in understanding the relationship between JC virus, etiology and PML-NBs.

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  • (PMID = 20464404.001).
  • [ISSN] 1432-0533
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2910879
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14. Csako G, Costello R, Shamim EA, O'Hanlon TP, Tran A, Clauw DJ, Williams HJ, Miller FW: Serum proteins and paraproteins in women with silicone implants and connective tissue disease: a case-control study. Arthritis Res Ther; 2007;9(5):R95
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  • [Title] Serum proteins and paraproteins in women with silicone implants and connective tissue disease: a case-control study.
  • Prior studies have suggested abnormalities of serum proteins, including paraproteins, in women with silicone implants but did not control for the presence of connective-tissue disease (CTD).
  • This retrospective case-control study, performed in tertiary-care academic centers, assessed possible alterations of serum proteins, including paraproteins, in such a population.
  • Seventy-four women with silicone implants who subsequently developed CTD, and 74 age-matched and CTD-matched women without silicone implants, were assessed in the primary study; other groups were used for additional comparisons.
  • Routine serum protein determinations and high-sensitivity protein electrophoresis and immunofixation electrophoresis were performed for detection of paraproteins.
  • Women with silicone implants, either with or without CTD, had significantly lower serum total protein and alpha1-globulin, alpha2-globulin, beta-globulin, gamma-globulin, and IgG levels compared with those without silicone implants.
  • There was no significant difference, however, in the frequency of paraproteinemia between women with silicone implants and CTD (9.5%) and age-matched and CTD-matched women without silicone implants (5.4%) (odds ratio, 1.82; 95% confidence interval, 0.51-6.45).
  • Paraprotein isotypes were similar in the two groups, and the clinical characteristics of the 13 women with paraproteinemia were comparable with an independent population of 10 women with silicone breast implants, CTD, and previously diagnosed monoclonal gammopathies.
  • In summary, this first comprehensive study of serum proteins in women with silicone implants and CTD found no substantially increased risk of monoclonal gammopathy.
  • Women with silicone implants, however, had unexpectedly low serum globulin and immunoglobulin levels, with or without the subsequent development of CTD.
  • The causes and clinical implications of these findings require further investigation.

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  • (PMID = 17875216.001).
  • [ISSN] 1478-6362
  • [Journal-full-title] Arthritis research & therapy
  • [ISO-abbreviation] Arthritis Res. Ther.
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Blood Proteins; 0 / Paraproteins; 0 / Silicone Gels
  • [Other-IDs] NLM/ PMC2212583
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15. Youd M, Blickarz C, Woodworth L, Touzjian T, Edling A, Tedstone J, Ruzek M, Tubo R, Kaplan J, Lodie T: Allogeneic mesenchymal stem cells do not protect NZBxNZW F1 mice from developing lupus disease. Clin Exp Immunol; 2010 Jul 1;161(1):176-86
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  • [MeSH-minor] Animals. Antibodies, Antinuclear / biosynthesis. Antibodies, Antinuclear / immunology. Antigen-Antibody Complex / analysis. Autoantigens / immunology. Bone Marrow / pathology. Cells, Cultured / transplantation. Crosses, Genetic. Cytokines / analysis. DNA / immunology. Female. Kidney Glomerulus / immunology. Kidney Glomerulus / pathology. Lupus Nephritis / etiology. Lupus Nephritis / pathology. Lymphocyte Activation. Male. Mice. Mice, Inbred BALB C. Mice, Inbred NZB. Mice, Inbred Strains. Plasma Cells / pathology. Proteinuria / etiology. Proteinuria / pathology. T-Lymphocytes / immunology. Transplantation, Homologous

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  • (PMID = 20456409.001).
  • [ISSN] 1365-2249
  • [Journal-full-title] Clinical and experimental immunology
  • [ISO-abbreviation] Clin. Exp. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antigen-Antibody Complex; 0 / Autoantigens; 0 / Cytokines; 9007-49-2 / DNA
  • [Other-IDs] NLM/ PMC2940163
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16. Wang SS, Abdou AM, Morton LM, Thomas R, Cerhan JR, Gao X, Cozen W, Rothman N, Davis S, Severson RK, Bernstein L, Hartge P, Carrington M: Human leukocyte antigen class I and II alleles in non-Hodgkin lymphoma etiology. Blood; 2010 Jun 10;115(23):4820-3
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  • [Title] Human leukocyte antigen class I and II alleles in non-Hodgkin lymphoma etiology.
  • Our results support a role for HLA in the etiology of NHL and its subtypes.

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  • (PMID = 20385791.001).
  • [ISSN] 1528-0020
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / PC / N01-PC-67008; United States / NCI NIH HHS / CN / N01 PC067009; United States / NCI NIH HHS / PC / N02-PC-71105; United States / NCI NIH HHS / PC / N01-PC-67010; United States / NCI NIH HHS / PC / N01 PC067010; United States / NCI NIH HHS / PC / N01-PC-65064; United States / NCI NIH HHS / PC / N01 PC067008; United States / NCI NIH HHS / PC / N01-PC-67009; United States / Intramural NIH HHS / / ; None / None / / N01 PC065064; United States / PHS HHS / / HHSN261200800001E; United States / CCR NIH HHS / RC / HHSN261200800001C; United States / NCI NIH HHS / CA / HHSN261200800001E
  • [Publication-type] Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Histocompatibility Antigens Class I; 0 / Histocompatibility Antigens Class II
  • [Other-IDs] NLM/ PMC2890176
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17. Yang HP, Dai M, Zhang DH: [Progress of study on suppressor of cytokine signaling-1 - review]. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2007 Apr;15(2):437-40
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  • It plays an important role in the development of leukemia, rheumatoid arthritis, liver cirrhosis and liver cancer.

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  • (PMID = 17493365.001).
  • [ISSN] 1009-2137
  • [Journal-full-title] Zhongguo shi yan xue ye xue za zhi
  • [ISO-abbreviation] Zhongguo Shi Yan Xue Ye Xue Za Zhi
  • [Language] CHI
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Interleukin-6; 0 / Intracellular Signaling Peptides and Proteins; 0 / LIF protein, human; 0 / Leukemia Inhibitory Factor; 0 / SOCS1 protein, human; 0 / Suppressor of Cytokine Signaling Proteins
  • [Number-of-references] 22
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18. Robazzi TC, Barreto JH, Silva LR, Santiago MB, Mendonça N: Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil. J Pediatr Hematol Oncol; 2007 Sep;29(9):622-6
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  • RESULTS: Acute lymphocytic leukemia (ALL) was diagnosed in 313 (77.1%) patients and acute myeloid leukemia (AML), in 93 (22.9%) patients, including 241 males (59.4%) and 165 females (40.6%).
  • Prior referral to our center, the most frequent initial diagnosis was anemia (15.8%), leukemia (15.0%), amygdalitis (3.7%), and rheumatic fever (2.7%).
  • The presence of joint tenderness (16.2% in ALLx5.4% in AML), arthritis (26.6% in ALLx9.7 in AML), bone tenderness (26.1% in ALLx16.1% in AML), limb tenderness (49.5% in ALLx25.8% in AML), and antalgic gait (32.8% in ALLx9.7% in AML) had higher prevalence on ALL.
  • CONCLUSIONS: AL should be considered on the differential diagnosis of osteoarticular symptoms of unknown etiology in children.
  • [MeSH-major] Leukemia, Myeloid / diagnosis. Osteoarthritis / diagnosis. Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis

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  • (PMID = 17805037.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Cwiklińska M, Balwierz W: [Osteoarticular pains as early manifestation of malignancies in children]. Przegl Lek; 2009;66(1-2):39-44
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  • [Title] [Osteoarticular pains as early manifestation of malignancies in children].
  • When these complaints predominate in the clinical presentation, they lead the diagnosis towards nonmalignant conditions, that are most common cause of such symptoms in children, like injuries, nonspecific reactive arthritis or inflammatory connective tissue diseases.
  • [MeSH-major] Arthralgia / etiology. Arthritis / etiology. Neoplasms / complications. Neoplasms / diagnosis. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications. Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Fever / etiology. Hepatomegaly / etiology. Humans. Infant. Male. Retrospective Studies. Spinal Cord Compression / etiology. Splenomegaly / etiology. Weight Loss

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  • (PMID = 19485254.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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20. Askling J, Brandt L, Lapidus A, Karlén P, Björkholm M, Löfberg R, Ekbom A: Risk of haematopoietic cancer in patients with inflammatory bowel disease. Gut; 2005 May;54(5):617-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Hematologic Neoplasms / etiology. Inflammatory Bowel Diseases / complications
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Colitis, Ulcerative / complications. Colitis, Ulcerative / epidemiology. Crohn Disease / complications. Crohn Disease / epidemiology. Epidemiologic Methods. Female. Hospitalization. Humans. Infant. Infant, Newborn. Leukemia, Myeloid / epidemiology. Leukemia, Myeloid / etiology. Lymphoma / epidemiology. Lymphoma / etiology. Male. Middle Aged. Sweden / epidemiology

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  • (PMID = 15831904.001).
  • [ISSN] 0017-5749
  • [Journal-full-title] Gut
  • [ISO-abbreviation] Gut
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1774486
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21. Kaşifoğlu T, Korkmaz C, Yaşar S, Gülbaş Z: Scleroderma and chronic myeloid leukemia: a sheer coincidence, a consequence of long lasting D-penicillamine therapy or a plausible relationship of both diseases? Rheumatol Int; 2006 Dec;27(2):175-7
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  • [Title] Scleroderma and chronic myeloid leukemia: a sheer coincidence, a consequence of long lasting D-penicillamine therapy or a plausible relationship of both diseases?
  • Systemic sclerosis is a chronic multisystem disorder of unknown etiology characterized by the involvement of skin and visceral organs caused by an accumulation of collagen.
  • Multiple myeloma and chronic lymphocytic leukemia are the most common hematological malignancies seen in patients with systemic sclerosis.
  • Chronic myeloid leukemia (CML) has only rarely been reported so far.
  • [MeSH-major] Antirheumatic Agents / adverse effects. CREST Syndrome / complications. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications. Penicillamine / adverse effects


22. Shah N, Zambidis ET: False-photosensitivity and transient hemiparesis following high-dose intravenous and intrathecal methotrexate for treatment of acute lymphoblastic leukemia. Pediatr Blood Cancer; 2009 Jul;53(1):103-5
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  • [Title] False-photosensitivity and transient hemiparesis following high-dose intravenous and intrathecal methotrexate for treatment of acute lymphoblastic leukemia.
  • We describe a patient who was treated with high-dose intravenous and intrathecal methotrexate for acute lymphoblastic leukemia, and who manifested a false photosensitivity reaction with no prior evidence of sun exposure.
  • The etiology of these events is obscure, but suggestive of a vasculitic or immune-mediated reaction to methotrexate.

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  • [Copyright] Copyright 2009 Wiley-Liss, Inc.
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  • (PMID = 19326416.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / HL077595-01; United States / NHLBI NIH HHS / HL / HL077595-05; United States / NHLBI NIH HHS / HL / K08 HL077595-01; United States / NHLBI NIH HHS / HL / K08 HL077595-05; United States / NHLBI NIH HHS / HL / HL077595-04; United States / NHLBI NIH HHS / HL / K08 HL077595-02; United States / NHLBI NIH HHS / HL / HL077595-02; United States / NHLBI NIH HHS / HL / K08 HL077595-03; United States / NHLBI NIH HHS / HL / K08 HL077595-04; United States / NHLBI NIH HHS / HL / K08 HL077595; United States / NHLBI NIH HHS / HL / HL077595-03
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Nucleic Acid Synthesis Inhibitors; YL5FZ2Y5U1 / Methotrexate
  • [Other-IDs] NLM/ NIHMS129680; NLM/ PMC3073488
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23. Landgren O, Engels EA, Caporaso NE, Gridley G, Mellemkjaer L, Hemminki K, Linet MS, Goldin LR: Patterns of autoimmunity and subsequent chronic lymphocytic leukemia in Nordic countries. Blood; 2006 Jul 1;108(1):292-6
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  • [Title] Patterns of autoimmunity and subsequent chronic lymphocytic leukemia in Nordic countries.
  • A population-based case-control study was conducted to evaluate risk of developing chronic lymphocytic leukemia (CLL) associated with personal and/or family history of autoimmune and related diseases.
  • If our results are confirmed, mechanistic studies examining how pernicious anemia might promote increased occurrence of CLL and how chronic rheumatic heart disease protects against CLL, perhaps related to long-term antibiotics use, may provide insights to the as-yet-unknown etiology of CLL.

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  • (PMID = 16527887.001).
  • [ISSN] 0006-4971
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1895837
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24. Worch J, Ritter J, Frühwald MC: Presentation of acute promyelocytic leukemia as granulocytic sarcoma. Pediatr Blood Cancer; 2008 Mar;50(3):657-60
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  • [Title] Presentation of acute promyelocytic leukemia as granulocytic sarcoma.
  • This extramedullary tumor can present before, concurrent with or after the diagnosis of acute myeloid leukemia.
  • GS is extremely uncommon in acute promyelocytic leukemia (APL).
  • [MeSH-major] Diagnostic Errors. Leukemia, Promyelocytic, Acute / complications. Sarcoma, Myeloid / etiology
  • [MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Arthritis, Psoriatic / diagnosis. Biomarkers, Tumor / analysis. Female. Humans. Oncogene Proteins, Fusion / analysis. Osteolysis / etiology. Osteomyelitis / diagnosis. Remission Induction. Shoulder Pain / etiology. Tretinoin / administration & dosage

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17437290.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Oncogene Proteins, Fusion; 0 / promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein; 5688UTC01R / Tretinoin
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25. Senel S, Kaya E, Aydogdu I, Erkurt MA, Kuku I: Rheumatic diseases and chronic myelogenous leukemia, presentation of four cases and review of the literature. Rheumatol Int; 2006 Jul;26(9):857-61
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  • [Title] Rheumatic diseases and chronic myelogenous leukemia, presentation of four cases and review of the literature.
  • We report four patients with rheumatic disease (RD) and chronic myelogenous leukemia (CML).
  • In two patients with Behcet's disease (BD) and rheumatoid arthritis (RA), CML developed after RD, in two patients with diffuse cutaneous systemic sclerosis and spondyloarthropathy, RD was diagnosed after CML.
  • [MeSH-major] Behcet Syndrome / etiology. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / etiology. Rheumatic Diseases / etiology
  • [MeSH-minor] Adult. Aged. Female. Humans. Hydroxyurea / therapeutic use. Middle Aged. Scleroderma, Systemic / etiology. Spondylarthritis / etiology

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  • (PMID = 16404564.001).
  • [ISSN] 0172-8172
  • [Journal-full-title] Rheumatology international
  • [ISO-abbreviation] Rheumatol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] X6Q56QN5QC / Hydroxyurea
  • [Number-of-references] 25
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26. Stamp L, Searle M, O'Donnell J, Chapman P: Gout in solid organ transplantation: a challenging clinical problem. Drugs; 2005;65(18):2593-611
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  • [MeSH-major] Gout / etiology. Gout / therapy. Organ Transplantation / adverse effects
  • [MeSH-minor] Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Diet. Drug Interactions. Glucocorticoids / therapeutic use. Gout Suppressants / therapeutic use. Health Behavior. Humans. Hyperuricemia / etiology. Hyperuricemia / physiopathology. Immunosuppressive Agents / adverse effects. Patient Education as Topic. Risk Assessment. Risk Factors

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  • (PMID = 16392875.001).
  • [ISSN] 0012-6667
  • [Journal-full-title] Drugs
  • [ISO-abbreviation] Drugs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] New Zealand
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Glucocorticoids; 0 / Gout Suppressants; 0 / Immunosuppressive Agents
  • [Number-of-references] 197
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27. Oohashi E, Yamada K, Oohashi M, Ueda J: Chronic progressive polyarthritis in a female cat. J Vet Med Sci; 2010 Apr;72(4):511-4
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  • Both feline leukemia virus antigen and feline immunodeficiency virus antibody were positive.

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  • (PMID = 20009422.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Viral; 0 / Immunosuppressive Agents; 83HN0GTJ6D / Cyclosporine
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28. Mencher SK, Wang LG: Promiscuous drugs compared to selective drugs (promiscuity can be a virtue). BMC Clin Pharmacol; 2005;5:3
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  • An example is chronic myeloid leukemia (CML).
  • DISCUSSION: There is a burgeoning understanding of the cellular mechanisms that control the etiology and pathogeneses of diseases.
  • SUMMARY: We contend that an ideal drug may be one whose efficacy is based not on the inhibition of a single target, but rather on the rebalancing of the several proteins or events, that contribute to the etiology, pathogeneses, and progression of diseases, i.e., in effect a promiscuous drug.

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  • (PMID = 15854222.001).
  • [ISSN] 1472-6904
  • [Journal-full-title] BMC clinical pharmacology
  • [ISO-abbreviation] BMC Clin Pharmacol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Drugs, Investigational; 0 / Pharmaceutical Preparations
  • [Number-of-references] 48
  • [Other-IDs] NLM/ PMC1090568
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29. Westhoff B, Jäger M, Krauspe R: [Osteonecrosis after chemotherapy in children]. Orthopade; 2008 Jan;37(1):56-62
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  • The etiology remains unclear.

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  • (PMID = 18210081.001).
  • [ISSN] 0085-4530
  • [Journal-full-title] Der Orthopade
  • [ISO-abbreviation] Orthopade
  • [Language] ger
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Bone Density Conservation Agents; 0 / Diphosphonates
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30. Zhao X, Zhou K, Wang HJ, Zhang L, Liu QG, Jing LP, Li HQ, Yang DL, Chu YL, Zhang FK: [The clinical and laboratory characteristics of T cell large granular lymphocyte leukemia]. Zhonghua Xue Ye Xue Za Zhi; 2009 Mar;30(3):179-82
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  • [Title] [The clinical and laboratory characteristics of T cell large granular lymphocyte leukemia].
  • OBJECTIVE: To analyze the characteristics of T-cell large granular lymphocyte leukemia (T-LGLL).
  • Rheumatoid arthritis was not present in any patients.
  • [MeSH-major] Leukemia, Large Granular Lymphocytic / diagnosis. Leukemia, Large Granular Lymphocytic / immunology
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Immunophenotyping. Immunosuppression. Male. Middle Aged. Red-Cell Aplasia, Pure / etiology. Retrospective Studies. Young Adult

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  • (PMID = 19642367.001).
  • [ISSN] 0253-2727
  • [Journal-full-title] Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
  • [ISO-abbreviation] Zhonghua Xue Ye Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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31. Singh YP, Agarwal V, Krishnani N, Misra R: Enthesitis-related arthritis in Kikuchi-Fujimoto disease. Mod Rheumatol; 2008;18(5):492-5
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  • [Title] Enthesitis-related arthritis in Kikuchi-Fujimoto disease.
  • Articular manifestations in the form of arthralgias are common but frank arthritis is distinctly rare and dactylitis has not been reported yet.
  • Herein, we describe a young boy who presented with arthritis and dactylitis as the initial manifestation of KFD.
  • Two years earlier he presented with arthritis of the knee and ankle joints, which lasted for 12 months.
  • Work-up for infectious etiology, systemic lupus erythematosus and leukemia and lymphoma was negative.
  • Fever, lymphadenopathy and leukopenia dissipated with nonsteroidal anti inflammatory drug therapy, but the arthritis persisted.
  • A trial of methotrexate led to the resolution of the arthritis.

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  • (PMID = 18470474.001).
  • [ISSN] 1439-7595
  • [Journal-full-title] Modern rheumatology
  • [ISO-abbreviation] Mod Rheumatol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. O'Rielly DD, Rahman P: Pharmacogenetics of rheumatoid arthritis: Potential targets from susceptibility genes and present therapies. Pharmgenomics Pers Med; 2010;3:15-31
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  • [Title] Pharmacogenetics of rheumatoid arthritis: Potential targets from susceptibility genes and present therapies.
  • Rheumatoid arthritis (RA) is a chronic heterogeneous autoimmune disorder of unknown etiology resulting in inflammation in the synovium, cartilage, and bone.

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  • (PMID = 23226040.001).
  • [ISSN] 1178-7066
  • [Journal-full-title] Pharmacogenomics and personalized medicine
  • [ISO-abbreviation] Pharmgenomics Pers Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC3513198
  • [Keywords] NOTNLM ; pharmacogenetics / rheumatoid arthritis / susceptibility genes
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33. Cerhan JR, Ansell SM, Fredericksen ZS, Kay NE, Liebow M, Call TG, Dogan A, Cunningham JM, Wang AH, Liu-Mares W, Macon WR, Jelinek D, Witzig TE, Habermann TM, Slager SL: Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma. Blood; 2007 Dec 15;110(13):4455-63
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  • Our results suggest that genetic variation in genes associated with immune response (TRAF1, RIPK3, BAT2, and TLR6), mitogen-activated protein kinase (MAPK) signaling (MAP3K5, DUSP2, and CREB1), lymphocyte trafficking and migration (B3GNT3, SELPLG, and LSP1), and coagulation pathways (FGG and ITGB3) may be important in the etiology of NHL, and should be prioritized in replication studies.


34. Sokol L, Loughran TP Jr: Large granular lymphocyte leukemia. Curr Hematol Malig Rep; 2007 Oct;2(4):278-82
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  • [Title] Large granular lymphocyte leukemia.
  • Patients with symptomatic indolent T-cell or NK-cell LGL leukemia are usually treated with immunosuppressive therapies; in contrast, aggressive T-cell or NK-cell LGL leukemias require intensive chemotherapy regimens.
  • [MeSH-major] Leukemia, Large Granular Lymphocytic
  • [MeSH-minor] Adolescent. Adult. Antibodies, Monoclonal / therapeutic use. Antibodies, Monoclonal, Humanized. Antibodies, Neoplasm / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Clinical Trials as Topic. Combined Modality Therapy. Disease Progression. Female. Humans. Immunophenotyping. Killer Cells, Natural / pathology. Leukemia, T-Cell / complications. Leukemia, T-Cell / epidemiology. Leukemia, T-Cell / immunology. Leukemia, T-Cell / pathology. Leukemia, T-Cell / therapy. Male. Middle Aged. Myelodysplastic Syndromes / pathology. Neutropenia / etiology. Opportunistic Infections / etiology. Stem Cell Transplantation

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  • (PMID = 20425381.001).
  • [ISSN] 1558-822X
  • [Journal-full-title] Current hematologic malignancy reports
  • [ISO-abbreviation] Curr Hematol Malig Rep
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antibodies, Neoplasm; 3A189DH42V / alemtuzumab
  • [Number-of-references] 39
  •  go-up   go-down


35. Raetz EA, Cairo MS, Borowitz MJ, Blaney SM, Krailo MD, Leil TA, Reid JM, Goldenberg DM, Wegener WA, Carroll WL, Adamson PC, Children's Oncology Group Pilot Study: Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study. J Clin Oncol; 2008 Aug 1;26(22):3756-62
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  • [Title] Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study.
  • PURPOSE: To determine the tolerability and serum concentration of epratuzumab, a humanized monoclonal antibody targeting CD22, administered alone and in combination with reinduction chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL), and to preliminarily assess tumor targeting and efficacy.
  • Two dose-limiting toxicities occurred: one grade 4 seizure of unclear etiology and one asymptomatic grade 3 ALT elevation.

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  • (PMID = 18669463.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U10 CA098543; United States / NCI NIH HHS / CA / U10 CA98543
  • [Publication-type] Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / CD22 protein, human; 0 / Sialic Acid Binding Ig-like Lectin 2; 0 / epratuzumab
  • [Other-IDs] NLM/ PMC2654811
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36. Askling J, Klareskog L, Blomqvist P, Fored M, Feltelius N: Risk for malignant lymphoma in ankylosing spondylitis: a nationwide Swedish case-control study. Ann Rheum Dis; 2006 Sep;65(9):1184-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Lymphoma / etiology. Spondylitis, Ankylosing / complications
  • [MeSH-minor] Adult. Aged. Epidemiologic Methods. Female. Hospitalization / statistics & numerical data. Humans. Leukemia, Lymphocytic, Chronic, B-Cell / epidemiology. Leukemia, Lymphocytic, Chronic, B-Cell / etiology. Lymphoma, Non-Hodgkin / epidemiology. Lymphoma, Non-Hodgkin / etiology. Male. Middle Aged. Sweden / epidemiology


37. Kim MK, Park JW, Park SH, Bang SM, Chung JG, Ahn JY, Baek HJ: Neutrophilic myositis without cutaneous involvement as the first manifestation of acute myeloid leukemia. Korean J Intern Med; 2005 Dec;20(4):346-8
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  • [Title] Neutrophilic myositis without cutaneous involvement as the first manifestation of acute myeloid leukemia.
  • Herein, we report a case of acute febrile neutrophilic myositis, without cutaneous involvement, as the first manifestation of acute myeloid leukemia.
  • All culture reports were negative, and he was finally diagnosed as having acute febrile neutrophilic myositis, associated with acute myeloid leukemia.
  • [MeSH-major] Leukemia, Myeloid, Acute / diagnosis. Myositis / etiology. Neutrophils / metabolism
  • [MeSH-minor] Adult. Fever / etiology. Humans. Male


38. Biswas S, Keddington J, McClanathan J: Large B-cell lymphoma presenting as acute abdominal pain and spontaneous splenic rupture; a case report and review of relevant literature. World J Emerg Surg; 2006;1:35
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  • Acute leukemia and non Hodgkin lymphoma were the frequent causes followed by chronic myelogenous leukemia.
  • We present a case report of a "spontaneous splenic rupture" and discuss the presentation, etiology and treatment options along with discussion of relevant literature.

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  • [Journal-full-title] World journal of emergency surgery : WJES
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39. Ramakrishnan A, Deeg HJ: A novel role for the marrow microenvironment in initiating and sustaining hematopoietic disease. Expert Opin Biol Ther; 2009 Jan;9(1):21-8
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  • [Title] A novel role for the marrow microenvironment in initiating and sustaining hematopoietic disease.
  • BACKGROUND: The marrow microenvironment is composed of a complex network of cells and extra cellular matrix that cooperate to regulate normal hematopoiesis.
  • There is growing evidence that microenvironmental defects can contribute to the pathogenesis of hematological malignancies.
  • OBJECTIVE/METHODS: We review the role of the microenvironment in inducing and sustaining hematological malignancies.
  • RESULTS/CONCLUSIONS: Two basic mechanisms could explain the role of microenvironmental defects in the evolution of hematopoietic neoplasms.
  • There is significant data to support the first mechanism, in which the malignant hematopoietic clone induces reversible functional changes in the microenvironment that result in improved growth conditions for the malignant cells.
  • More recent studies from mouse models have indicated that a second mechanism involving primary microenvironmental defects can also result in malignancy.

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  • (PMID = 19063690.001).
  • [ISSN] 1744-7682
  • [Journal-full-title] Expert opinion on biological therapy
  • [ISO-abbreviation] Expert Opin Biol Ther
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL082941; United States / NHLBI NIH HHS / HL / HL082941; United States / NHLBI NIH HHS / HL / R01 HL082941-04; United States / NHLBI NIH HHS / HL / P01 HL036444; United States / NHLBI NIH HHS / HL / P01 HL036444-30; United States / NHLBI NIH HHS / HL / HL082941-04; United States / NHLBI NIH HHS / HL / HL03644
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] England
  • [Number-of-references] 90
  • [Other-IDs] NLM/ NIHMS214623; NLM/ PMC2911479
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40. Schwarzberg AB, Alexander CB, DeAngelo DJ, Helfgott SM: Clinical problem-solving. A joint venture. N Engl J Med; 2008 Jun 5;358(23):2496-501
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Arthritis / etiology. Bone Marrow / pathology. Joints / pathology. Leukemia, Myelomonocytic, Acute / diagnosis. Leukemic Infiltration / diagnosis. Skin / pathology. Synovial Fluid / immunology
  • [MeSH-minor] Diagnosis, Differential. Dyspnea / etiology. Exanthema / etiology. Eye / pathology. Fatigue / etiology. Female. Humans. Leukocytes, Mononuclear. Middle Aged. Urinary Bladder Neoplasms / complications

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  • (PMID = 18525046.001).
  • [ISSN] 1533-4406
  • [Journal-full-title] The New England journal of medicine
  • [ISO-abbreviation] N. Engl. J. Med.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / 2P01CA 066996-11A1; United States / NCI NIH HHS / CA / P01CA68484
  • [Publication-type] Case Reports; Clinical Conference; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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41. Hu RQ, Mehter H, Nadasdy T, Satoskar A, Spetie DN, Rovin BH, Hebert L: Severe hemorrhagic cystitis associated with prolonged oral cyclophosphamide therapy: case report and literature review. Rheumatol Int; 2008 Sep;28(11):1161-4
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  • She survived her acute illness only to die 2 months later of acute leukemia.
  • [MeSH-minor] Blood Transfusion. Fatal Outcome. Female. Glomerulonephritis / etiology. Granulomatosis with Polyangiitis / drug therapy. Hematuria / etiology. Hemorrhage / therapy. Humans. Middle Aged

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  • (PMID = 18398616.001).
  • [ISSN] 0172-8172
  • [Journal-full-title] Rheumatology international
  • [ISO-abbreviation] Rheumatol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
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42. Kumana CR: Aspects of general medicine. Hong Kong Med J; 2008 Oct;14(5):385-90
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  • The chapters summarised include: Contemporary management of acute myocardial infarction; Imported infectious disease emergencies; New therapies in the management of type 2 diabetes; Stress and adrenal insufficiency; Making sense of a 'funny thyroid function test'; Myeloproliferative disorders: management and molecular pathogenesis; Drug allergies; Osteoporosis; Rheumatoid arthritis; Understanding migraine from bench to bedside.

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  • (PMID = 18840910.001).
  • [ISSN] 1024-2708
  • [Journal-full-title] Hong Kong medical journal = Xianggang yi xue za zhi
  • [ISO-abbreviation] Hong Kong Med J
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 2
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43. Koshiol J, Gridley G, Engels EA, McMaster ML, Landgren O: Chronic immune stimulation and subsequent Waldenström macroglobulinemia. Arch Intern Med; 2008 Sep 22;168(17):1903-9
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  • These findings provide novel insights into the still unknown etiology of WM.
  • [MeSH-major] Autoimmune Diseases / complications. Waldenstrom Macroglobulinemia / etiology. Waldenstrom Macroglobulinemia / immunology


44. Toffalini F, Hellberg C, Demoulin JB: Critical role of the platelet-derived growth factor receptor (PDGFR) beta transmembrane domain in the TEL-PDGFRbeta cytosolic oncoprotein. J Biol Chem; 2010 Apr 16;285(16):12268-78
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  • [MeSH-minor] Amino Acid Sequence. Animals. Cell Line. Cell Proliferation. Cell Transformation, Neoplastic / genetics. Cell Transformation, Neoplastic / metabolism. Cytosol / metabolism. Humans. Leukemia, Myeloid / etiology. Leukemia, Myeloid / genetics. Leukemia, Myeloid / metabolism. Molecular Sequence Data. Myeloid Cells / metabolism. Myeloid Cells / pathology. Protein Structure, Tertiary. Recombinant Proteins / chemistry. Recombinant Proteins / genetics. Recombinant Proteins / metabolism. Sequence Deletion. Signal Transduction. Swine

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  • (PMID = 20164181.001).
  • [ISSN] 1083-351X
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Oncogene Proteins, Fusion; 0 / Recombinant Proteins; 0 / TEL-PDGFRbeta fusion protein, human
  • [Other-IDs] NLM/ PMC2852966
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45. Cutler C, Miklos D, Kim HT, Treister N, Woo SB, Bienfang D, Klickstein LB, Levin J, Miller K, Reynolds C, Macdonell R, Pasek M, Lee SJ, Ho V, Soiffer R, Antin JH, Ritz J, Alyea E: Rituximab for steroid-refractory chronic graft-versus-host disease. Blood; 2006 Jul 15;108(2):756-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Antibodies, Monoclonal, Murine-Derived. B-Lymphocytes / drug effects. B-Lymphocytes / pathology. Chronic Disease. Female. Humans. Male. Middle Aged. Musculoskeletal Diseases / drug therapy. Musculoskeletal Diseases / etiology. Prednisone / pharmacology. Rituximab. Salvage Therapy / methods. Skin Diseases / drug therapy. Skin Diseases / etiology

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  • (PMID = 16551963.001).
  • [ISSN] 0006-4971
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT00136396
  • [Grant] United States / NHLBI NIH HHS / HL / P01 HL070149
  • [Publication-type] Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Steroids; 4F4X42SYQ6 / Rituximab; VB0R961HZT / Prednisone
  • [Other-IDs] NLM/ PMC1895490
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46. Miesbach W, Scharrer I, Asherson R: Thrombotic manifestations of the antiphospholipid syndrome in patients with malignancies. Clin Rheumatol; 2006 Nov;25(6):840-4
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  • [MeSH-major] Antiphospholipid Syndrome / complications. Neoplasms / complications. Thrombosis / etiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antibodies, Antiphospholipid / blood. Female. Hematologic Neoplasms / complications. Humans. Incidence. Leukemia / complications. Lymphoma / complications. Male. Medical Records. Middle Aged. Retrospective Studies. Thromboembolism / epidemiology. Thromboembolism / etiology

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  • (PMID = 16435159.001).
  • [ISSN] 0770-3198
  • [Journal-full-title] Clinical rheumatology
  • [ISO-abbreviation] Clin. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Antiphospholipid
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47. Grossberg AJ, Scarlett JM, Marks DL: Hypothalamic mechanisms in cachexia. Physiol Behav; 2010 Jul 14;100(5):478-89
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  • This combination is found in a number of disorders including cancer, cystic fibrosis, AIDS, rheumatoid arthritis, renal failure, and Alzheimer's disease.
  • This has led to intense investigation of cachexia and the proposal of numerous hypotheses regarding its etiology.

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
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