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1. Pahlavan PS, Kanthan R: Goblet cell carcinoid of the appendix. World J Surg Oncol; 2005 Jun 20;3:36

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet cell carcinoid of the appendix.
  • BACKGROUND: Goblet cell carcinoid (GCC) of the appendix is a rare neoplasm that share histological features of both adenocarcinoma and carcinoid tumor.
  • While its malignant potential remains unclear, GCC's are more aggressive than conventional carcinoid.
  • This review summarizes the published literature on GCC of the appendix.
  • The focus is on its diagnosis, histopathological aspects, clinical manifestations, and management.
  • METHODS: Published studies in the English language between 1966 to 2004 were identified through Medline keyword search utilizing terms "goblet cell carcinoid," "adenocarcinoid", "mucinous carcinoid" and "crypt cell carcinoma" of the appendix.
  • RESULTS: Based on the review of 57 published papers encompassing nearly 600 diagnosed patients, the mean age of presentation for GCC of the appendix was 58.89 years with equal representation in both males and females.
  • Accurate diagnosis of this neoplasm requires astute observations within an acutely inflamed appendix as this neoplasm has a prominent pattern of submucosal growth and usually lacks the formation of a well-defined tumor mass.
  • Concomitant distant metastasis at diagnosis was present in 11.16% of patients with the ovaries being the most common site in 3.60% followed by disseminated abdominal carcinomatosis in 1.03%.
  • Local lymph node involvement was seen in 8.76% of patients at the time of diagnosis.
  • GCC's of the appendix remains a neoplasm of unpredictable biological behavior and thus warrants lifelong surveillance for recurrence of the disease upon diagnosis and successful surgical extirpation.
  • CONCLUSION: GCC of the appendix is a rare neoplasm.
  • Due to its wide range of presentation, this tumor should be considered as a possible diagnosis in many varied situations leading to abdominal surgery.
  • In female patients with GCC of the appendix regardless of age, bilateral salpingo-oophorectomy is advocated.

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  • [Cites] Dis Colon Rectum. 1987 Feb;30(2):112-5 [3803115.001]
  • [Cites] Cancer. 1974 Mar;33(3):770-7 [4815580.001]
  • [Cites] Cancer. 1974 Aug;34(2):338-44 [4852178.001]
  • [Cites] Cancer. 1979 Nov;44(5):1700-6 [498041.001]
  • [Cites] Pathol Res Pract. 1984 Jul;178(6):555-61 [6483683.001]
  • [Cites] Gastroenterology. 1984 Feb;86(2):302-9 [6690357.001]
  • [Cites] Hum Pathol. 1982 Mar;13(3):286-8 [7076213.001]
  • [Cites] Am J Surg Pathol. 1982 Mar;6(2):188-9 [7102895.001]
  • [Cites] Acta Obstet Gynecol Scand. 1982;61(2):153-6 [7113691.001]
  • [Cites] Diagn Gynecol Obstet. 1980 Winter;2(4):269-74 [7215111.001]
  • [Cites] Am J Surg Pathol. 1981 Apr;5(3):213-24 [7235117.001]
  • [Cites] Cancer. 1978 Dec;42(6):2687-95 [728868.001]
  • [Cites] Cancer. 1978 Dec;42(6):2781-93 [728874.001]
  • [Cites] Virchows Arch A Pathol Anat Histol. 1980;386(2):201-10 [7368563.001]
  • [Cites] Acta Morphol Acad Sci Hung. 1980;28(1-2):37-58 [7446221.001]
  • [Cites] J Clin Pathol. 1995 Sep;48(9):869-70 [7490325.001]
  • [Cites] Diagn Cytopathol. 1995 Feb;12(1):59-61 [7789249.001]
  • [Cites] Intern Med. 1994 Jul;33(7):422-6 [7949643.001]
  • [Cites] Am J Surg. 1994 Dec;168(6):685-7 [7978019.001]
  • [Cites] J Clin Pathol. 1977 May;30(5):473-80 [864014.001]
  • [Cites] Histopathology. 1995 Dec;27(6):557-62 [8838336.001]
  • [Cites] Int J Gynecol Pathol. 1996 Jan;15(1):85-8 [8852453.001]
  • [Cites] Am J Surg Pathol. 1997 Jan;21(1):109-13 [8990147.001]
  • [Cites] Arch Pathol Lab Med. 1976 Jun;100(6):301-6 [946758.001]
  • [Cites] J Gastroenterol. 1998 Aug;33(4):582-7 [9719248.001]
  • [Cites] Ann Surg. 1999 Jun;229(6):815-21; discussion 822-3 [10363895.001]
  • [Cites] Cancer. 1999 Jul 1;86(1):14-21 [10391558.001]
  • [Cites] Eur J Surg. 1999 Oct;165(10):993-7 [10574110.001]
  • [Cites] Surg Today. 2000;30(1):78-81 [10648090.001]
  • [Cites] Arch Pathol Lab Med. 2001 Mar;125(3):386-90 [11231488.001]
  • [Cites] Am J Surg Pathol. 2001 May;25(5):557-68 [11342766.001]
  • [Cites] Pathol Int. 2001 Apr;51(4):283-7 [11350611.001]
  • [Cites] Eur J Obstet Gynecol Reprod Biol. 2001 Jul;97(1):90-5 [11435017.001]
  • [Cites] Eur J Surg Oncol. 2002 Mar;28(2):140-6 [11884049.001]
  • [Cites] Endocr Pathol. 2002 Spring;13(1):47-58 [12114750.001]
  • [Cites] Cancer. 2002 Jun 15;94(12):3307-12 [12115365.001]
  • [Cites] Am J Pathol. 2002 Aug;161(2):551-64 [12163380.001]
  • [Cites] Dig Dis Sci. 2002 Dec;47(12):2760-2 [12498298.001]
  • [Cites] Histopathology. 2003 Feb;42(2):137-40 [12558745.001]
  • [Cites] Surg Today. 2003;33(5):375-8 [12734735.001]
  • [Cites] Radiographics. 2003 May-Jun;23(3):645-62 [12740466.001]
  • [Cites] Br J Surg. 2003 Nov;90(11):1317-22 [14598408.001]
  • [Cites] Mod Pathol. 2003 Dec;16(12):1189-98 [14681318.001]
  • [Cites] Eur J Surg Oncol. 1992 Aug;18(4):386-7 [1521632.001]
  • [Cites] Am Surg. 2004 Jul;70(7):593-9 [15279181.001]
  • [Cites] Br J Surg. 2004 Sep;91(9):1168-73 [15449269.001]
  • [Cites] Diagn Cytopathol. 1991;7(2):155-7 [1648469.001]
  • [Cites] Histopathology. 1991 Jan;18(1):61-5 [1672861.001]
  • [Cites] Leber Magen Darm. 1991 Sep;21(5):226,229-30 [1758238.001]
  • [Cites] Br J Urol. 1976 Dec;48(6):436 [188508.001]
  • [Cites] Acta Pathol Jpn. 1991 Jun;41(6):455-60 [1950561.001]
  • [Cites] Am J Clin Pathol. 1990 Jul;94(1):27-35 [2163192.001]
  • [Cites] Arch Pathol Lab Med. 1979 Apr;103(4):180-2 [218519.001]
  • [Cites] Gut. 1990 Mar;31(3):322-4 [2323597.001]
  • [Cites] Gut. 1990 Jul;31(7):840 [2370022.001]
  • [Cites] Int Surg. 1989 Apr-Jun;74(2):109-10 [2753618.001]
  • [Cites] J Surg Oncol. 1988 Jan;37(1):65-71 [2826924.001]
  • [Cites] Arch Pathol Lab Med. 1985 Oct;109(10):930-3 [2994592.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1987;412(2):175-82 [3122418.001]
  • [Cites] Surg Gynecol Obstet. 1988 Jul;167(1):81-6 [3289135.001]
  • [Cites] Dis Colon Rectum. 1988 Aug;31(8):605-12 [3402286.001]
  • (PMID = 15967038.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1182398
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2. Gulubova MV, Yovchev Y, Vlaykova T, Hadjipetkov P, Prangova DK, Popharitov A: Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix. World J Surg Oncol; 2008;6:15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix.
  • BACKGROUND: Goblet cell carcinoids appear less frequently in the appendix than do other carcinoids.
  • In the presented work a case with a goblet cell carcinoid of the appendix is described.
  • METHODS: Routine histological and histochemical methods were employed, with a combination of histochemistry and immunohistochemistry on one section and light and electron microscopical immunohistochemisty on paraffin-embedded material, were applied to identify the type of the carcinoid and to reveal the fine structure of cell types in the tumour nests of the appendix.
  • RESULTS: During the biopsy of a patient who had undergone appendectomy, an infiltration with clusters of goblet cells in the submucosa of the appendix was found.
  • After a second operation of right-sided hemicolectomy, similar clusters of goblet cells were detected in the muscle layers of the caecum.
  • The ultrastructural immunohistochemistry showed that chromogranin A-positive cells had discoid and pleomorphic granules and were located in tumour nests or as single cells in the appendiceal wall.
  • CONCLUSION: The combined histochemical and immunohistochemical procedure and the ultrastructural immunohistochemistry on archival material could contribute in clarifying the diagnosis of goblet cell carcinoid.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Carcinoid Tumor / diagnosis

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  • [Cites] Mod Pathol. 1989 Nov;2(6):630-7 [2479945.001]
  • [Cites] Surg Gynecol Obstet. 1988 Jul;167(1):81-6 [3289135.001]
  • [Cites] Histopathology. 1995 Dec;27(6):557-62 [8838336.001]
  • [Cites] Cancer Metastasis Rev. 1997 Jun;16(1-2):179-205 [9156286.001]
  • [Cites] Histochem Cell Biol. 1997 Aug;108(2):105-13 [9272429.001]
  • [Cites] Acta Oncol. 2004;43(7):617-25 [15545182.001]
  • [Cites] Semin Diagn Pathol. 2000 May;17(2):91-103 [10839609.001]
  • [Cites] Arch Pathol Lab Med. 2001 Mar;125(3):386-90 [11231488.001]
  • [Cites] Histochem J. 2001 Feb;33(2):111-20 [11432639.001]
  • [Cites] Cancer. 2002 Jun 15;94(12):3307-12 [12115365.001]
  • [Cites] Virchows Arch. 2002 Sep;441(3):256-63 [12242522.001]
  • [Cites] Dig Dis Sci. 2003 Feb;48(2):295-8 [12643605.001]
  • [Cites] Mod Pathol. 2003 Dec;16(12):1189-98 [14681318.001]
  • [Cites] J Clin Pathol. 1976 Aug;29(8):687-92 [956450.001]
  • [Cites] Cancer. 1978 Dec;42(6):2687-95 [728868.001]
  • [Cites] Cancer. 1978 Dec;42(6):2781-93 [728874.001]
  • [Cites] Gastroenterology. 1984 Feb;86(2):302-9 [6690357.001]
  • [Cites] J Histochem Cytochem. 1985 Sep;33(9):959-64 [3860562.001]
  • [Cites] Am J Clin Pathol. 1990 Jul;94(1):27-35 [2163192.001]
  • (PMID = 18252007.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
  • [Other-IDs] NLM/ PMC2275273
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3. Alsaad KO, Serra S, Chetty R: Combined goblet cell carcinoid and mucinous cystadenoma of the vermiform appendix. World J Gastroenterol; 2009 Jul 21;15(27):3431-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combined goblet cell carcinoid and mucinous cystadenoma of the vermiform appendix.
  • Goblet cell carcinoid is an uncommon primary tumor of the vermiform appendix, characterized by dual endocrine and glandular differentiation.
  • Whether goblet cell carcinoid represents a morphological variant of appendiceal classical carcinoid or a mucin-producing adenocarcinoma is a matter of conjecture.
  • Rare cases of goblet cell carcinoid with other concomitant appendiceal epithelial neoplasms have been documented.
  • In this report, we describe a rare case of combined appendiceal goblet cell carcinoid and mucinous cystadenoma, and discuss the possible histopathogenesis of this combination.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Appendix / pathology. Carcinoid Tumor / pathology. Cystadenoma, Mucinous / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Female. Humans. Middle Aged

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  • [Cites] Arch Pathol Lab Med. 2001 Mar;125(3):386-90 [11231488.001]
  • [Cites] Am J Surg Pathol. 1981 Apr;5(3):213-24 [7235117.001]
  • [Cites] Cancer. 1995 Feb 1;75(3):757-68 [7828125.001]
  • [Cites] Endocr Pathol. 2007 Spring;18(1):16-22 [17652796.001]
  • [Cites] Histopathology. 1995 Dec;27(6):557-62 [8838336.001]
  • [Cites] Cancer. 1999 Jul 1;86(1):14-21 [10391558.001]
  • [Cites] J Clin Pathol. 1995 Sep;48(9):869-70 [7490325.001]
  • (PMID = 19610147.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2712907
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4. Buis CC, van Doorn HC, Dinjens WN, Ewing PC: Mucinous carcinoid of the ovary: report of a case with metastasis in the contralateral ovary after ten years. Rare Tumors; 2010;2(3):e39

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucinous carcinoid of the ovary: report of a case with metastasis in the contralateral ovary after ten years.
  • Monodermal teratomas of the ovary can take the form of carcinoid tumors of which there are several types, mucinous carcinoid being the least common.
  • Very few cases of primary mucinous carcinoid of the ovary have been reported in the literature and the behavior of these tumors over the long term is unclear.
  • We describe a case of primary mucinous carcinoid of the ovary in a 39-year-old woman treated with unilateral salpingo-oophorectomy, where a metastasis occurred in the contralateral ovary ten years later.
  • This case demonstrates that mucinous carcinoid of the ovary can metastasize even after a long interval, and careful follow-up of patients, particularly those treated conservatively, is appropriate.

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  • (PMID = 21139955.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994532
  • [Keywords] NOTNLM ; metastasis / mucinous carcinoid / ovary
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5. Maes M, Segers K, Cheyns P: Goblet cell carcinoid of the appendix: laparoscopic appendectomy or right hemicolectomy? Acta Chir Belg; 2008 Jul-Aug;108(4):447-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet cell carcinoid of the appendix: laparoscopic appendectomy or right hemicolectomy?
  • Goblet cell carcinoids are uncommon tumours with histological features of both adenocarcinoma and carcinoid tumour.
  • They occur predominantly in the appendix and although the malignant potential remains unclear, adenocarcinoids appear to be more aggressive than conventional carcinoids.
  • In this case report, we present a goblet cell carcinoid with laparoscopic operative treatment in two stages.
  • Macroscopically, a diffusely inflamed appendix was found with no sign of perforation.
  • Histopathological examination revealed a goblet cell carcinoid with characteristics of aggressive behaviour, indicating the need for laparoscopic right hemicolectomy in which, however, neither residual tumour nor metastatic lymph nodes could be found.
  • As they may present the same clinical presentation, pathological diagnosis is required to distinguish goblet cell carcinoid from acute appendicitis.
  • Two-stage surgery for goblet cell carcinoid is advocated in the literature, but the debate still continues as to whether the goblet cell carcinoid should be treated by appendectomy alone, as for most carcinoids, or by right hemicolectomy, as for the appendiceal adenocarcinoma.
  • [MeSH-major] Appendectomy / methods. Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery. Colectomy / methods. Laparoscopy / methods
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Follow-Up Studies. Humans

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  • (PMID = 18807600.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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6. Louthan O: [Goblet cell carcinoid of the appendix]. Vnitr Lek; 2009 Nov;55(11):1056-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Goblet cell carcinoid of the appendix].
  • [Transliterated title] Karcinoid appendixu s pohárkovými bunkami.
  • Appendiceal goblet cell carcinoids are mixed tumors including neuroendocrine cells and intestinal type of goblet cells.
  • Compared to typical carcinoids, goblet cell carcinoids are malignant tumors with degree of malignity differing from case to case.
  • Carcinoid syndrom is not present.
  • [MeSH-major] Appendiceal Neoplasms. Carcinoid Tumor

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  • (PMID = 20017437.001).
  • [ISSN] 0042-773X
  • [Journal-full-title] Vnitr̆ní lékar̆ství
  • [ISO-abbreviation] Vnitr Lek
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Czech Republic
  • [Number-of-references] 18
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7. Paklina OV, Setdikova GR, Nikitin PN, Petropavlovskiĭ AI: [Goblet-cell carcinoid of the colon]. Arkh Patol; 2008 Mar-Apr;70(2):45-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Goblet-cell carcinoid of the colon].
  • The authors describe a case of goblet-cell carcinoid of the appendix subject to additional immunohistological study.
  • Goblet-cell carcinoid is a rare colonic tumor comprises the morphological signs of adenocarcinoma and carcinoid.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoid Tumor / pathology. Colonic Neoplasms / pathology

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  • (PMID = 18540443.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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8. Roy P, Chetty R: Goblet cell carcinoid tumors of the appendix: An overview. World J Gastrointest Oncol; 2010 Jun 15;2(6):251-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet cell carcinoid tumors of the appendix: An overview.
  • Goblet cell carcinoid is an enigmatic and rare tumor involving the appendix almost exclusively.
  • Various other names have been used for this entity such as adenocarcinoid, mucinous carcinoid, crypt cell carcinoma, and mucin-producing neuroendocrine tumor, although none have been found to be completely satisfactory or universally accepted.
  • The tumor is thought to arise from pluripotent intestinal epithelial crypt-base stem cells by dual neuroendocrine and mucinous differentiation.
  • The histologic hallmark of this entity is the presence of clusters of goblet cells in the lamina propria or submucosa stain for various neuroendocrine markers, though the intensity is often patchy.
  • These may be of signet ring cell type or poorly differentiated adenocarcinoma.
  • Recently molecular studies have shown these tumors to lack the signatures of adenocarcinoma but they have some changes similar to that of ileal carcinoids (allelic loss of chromosome 11q, 16q and 18q).
  • The natural history of GCC is intermediate between carcinoids and adenocarcinomas of the appendix.

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  • (PMID = 21160637.001).
  • [ISSN] 1948-5204
  • [Journal-full-title] World journal of gastrointestinal oncology
  • [ISO-abbreviation] World J Gastrointest Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2998842
  • [Keywords] NOTNLM ; Appendiceal neoplasm / Goblet cell carcinoid / Mucin-producing neuroendocrine tumor of appendix
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9. Nakamura S, Kimura S, Kashima M, Shichijo K, Yoshida S, Harada E, Matsushita T, Oshima Y, Tamaki Y, Horiuchi N, Takeichi T, Fujimoto H, Masuda K, Iwasaka N, Shinomiya S: [A case of peritonitis carcinomatosa from goblet cell carcinoid of the appendix treated by intraperitoneal paclitaxel and systemic S-1 chemotherapy]. Gan To Kagaku Ryoho; 2008 Dec;35(13):2425-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of peritonitis carcinomatosa from goblet cell carcinoid of the appendix treated by intraperitoneal paclitaxel and systemic S-1 chemotherapy].
  • Goblet cell carcinoid of the appendix is a rare neoplasm and clinically tends to take a malignant course.
  • Abdominal computed tomography showed massive ascites and slight contrast enhancement of appendix.
  • A tumor was found by colonoscopic examination at the orifice of vermiform and was diagnosed pathologically as goblet cell carcinoid of the appendix.
  • We performed intraperitoneal paclitaxel(PTX)administration at 70 mg/m(2) week without any resection of the tumor.
  • For about one year, her tumor was controlled but became worse thirteen months after diagnosis and died.
  • It is thought that intraabdominal paclitaxel administration and systemic S-1 therapy can be one of appropriate forms of chemotherapy for inoperable peritoneal carcinomatosis from goblet cell carcinoid of appendix.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoid Tumor / drug therapy. Carcinoid Tumor / pathology. Oxonic Acid / therapeutic use. Paclitaxel / therapeutic use. Peritonitis / drug therapy. Peritonitis / pathology. Tegafur / therapeutic use

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  • (PMID = 19098416.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; P88XT4IS4D / Paclitaxel
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10. Suzuki O, Ono K, Sekishita Y, Fujimori M, Shiono T, Kondo S: Laparoscopic two-stage surgery for goblet cell carcinoid of the appendix: report of a case and review of the Japanese literature. Surg Laparosc Endosc Percutan Tech; 2006 Apr;16(2):106-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic two-stage surgery for goblet cell carcinoid of the appendix: report of a case and review of the Japanese literature.
  • Goblet cell carcinoid of the appendix is a rare clinical entity exhibiting features of both carcinoid and adenocarcinoma.
  • Here, we present the first report of laparoscopic 2-stage surgery for goblet cell carcinoid with a review of the Japanese literature.
  • A 49-year-old man underwent laparoscopic appendectomy under the diagnosis of acute appendicitis.
  • A pathologic diagnosis of goblet cell carcinoid, accompanied by the aggressive proliferation, with acute appendicitis was made.
  • Subsequent laparoscopic ileocecal resection was performed, and it was verified that there were neither residual tumor nor lymph node metastases.
  • Because goblet cell carcinoid may be difficult to clinically distinguish from acute appendicitis, pathologic examination is essential.
  • Depending upon the grade of tumor proliferation, additional resection should be considered, and our experience with this case suggests that laparoscopic 2-stage surgery is feasible for the adequate treatment of goblet cell carcinoid without complications.
  • [MeSH-major] Appendectomy / methods. Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery. Colectomy / methods. Laparoscopy / methods
  • [MeSH-minor] Anastomosis, Surgical / methods. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged

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  • (PMID = 16773013.001).
  • [ISSN] 1530-4515
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. van Eeden S, Offerhaus GJ, Hart AA, Boerrigter L, Nederlof PM, Porter E, van Velthuysen ML: Goblet cell carcinoid of the appendix: a specific type of carcinoma. Histopathology; 2007 Dec;51(6):763-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet cell carcinoid of the appendix: a specific type of carcinoma.
  • AIMS: Goblet cell carcinoid is a poorly understood tumour of the appendix.
  • The aim of this study was to determine whether it should be regarded as a separate entity or as a variant of classical carcinoid.
  • METHODS AND RESULTS: The immunohistochemical expression pattern of 21 markers and the mutation status of KRas codon 12 were determined in 16 goblet cell carcinoids and compared with 14 classical carcinoids, 19 colonic adenocarcinomas and 10 appendiceal mucinous cystadeno (carcino)mas.
  • Goblet cell carcinoids were significantly different from the control groups.
  • The most important markers for discriminating between the groups were CEA (classical carcinoid versus all others), KRas mutation (present in all mucinous cystadeno (carcino)mas), beta-catenin (goblet cell carcinoid versus left sided colonic adenocarcinoma) and chromogranin (goblet cell carcinoid versus right sided colonic adenocarcinoma).
  • Expression of Math1 and HD5 was similar in goblet cell carcinoid and colonic adenocarcinoma but absent in classical carcinoid.
  • CONCLUSION: The results suggest that goblet cell carcinoids should be regarded as a separate entity.
  • The formerly used term 'crypt cell carcinoma' may be more appropriate because it reflects the more aggressive clinical behaviour of these tumours as well as their greater similarity to adenocarcinomas rather than to carcinoids.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Biomarkers, Tumor / analysis. Carcinoid Tumor / pathology
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. DNA Mutational Analysis. Humans. Immunohistochemistry. Mutation. Polymerase Chain Reaction. Proto-Oncogene Proteins / genetics. ras Proteins / genetics

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  • [CommentIn] Histopathology. 2008 May;52(6):770-1 [18439158.001]
  • (PMID = 18042066.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Grant] United States / NIMHD NIH HHS / MD / 1P20 MD001824
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / KRAS protein, human; 0 / Proto-Oncogene Proteins; EC 3.6.5.2 / ras Proteins
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12. Chetty R, Klimstra DS, Henson DE, Albores-Saavedra J: Combined classical carcinoid and goblet cell carcinoid tumor: a new morphologic variant of carcinoid tumor of the appendix. Am J Surg Pathol; 2010 Aug;34(8):1163-7
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  • [Title] Combined classical carcinoid and goblet cell carcinoid tumor: a new morphologic variant of carcinoid tumor of the appendix.
  • Carcinoid tumors are the most common neoplasms of the appendix.
  • Histologically they have been categorized as classical, tubular, or goblet cell types.
  • Goblet cell carcinoid has been regarded as a distinctive tumor type, not related to classic carcinoids, and to our knowledge combinations of these 2 tumor types have not been described in detail.
  • In this report, we describe 5 cases of combined classical carcinoid and goblet cell carcinoid (GCC) tumors of the appendix.
  • The tumors (0.6 to 6.0 cm) were located in the mid-portion and the tip of the appendix.
  • All 5 appendiceal tumors had microscopic features of both classical carcinoid and GCC, either intimately admixed or separate but closely apposed.
  • The extent of the 2 components varied, with classical carcinoid representing 60% to 90% of the tumor.
  • The pelvic soft tissue and ovarian metastases in case 4 consisted predominantly of a signet ring cell carcinoma with a minor component of goblet cells and was interpreted as an adenocarcinoma ex-GCC.
  • In view of the fact that these combined carcinoid tumors appear to behave more as goblet cell carcinoids, detailed microscopic examination of classical carcinoid tumors of the appendix is suggested and larger series with longer follow-up is required to ascertain the true biologic potential of this unique form of combined carcinoid tumor of the appendix.
  • The occurrence of both carcinoid types in the same appendices suggests a closer histogenetic relationship than previously believed, although the possibility that the 2 components represent separate, independent primaries ("collision tumors") can also be considered.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology. Goblet Cells / pathology. Mixed Tumor, Malignant / pathology
  • [MeSH-minor] Appendectomy. Biomarkers, Tumor / analysis. Colectomy. Female. Humans. Immunohistochemistry. Male. Middle Aged. Mitotic Index. Neoplasm Invasiveness. Treatment Outcome

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  • [CommentIn] Am J Surg Pathol. 2011 Aug;35(8):1248-50 [21753706.001]
  • (PMID = 20631606.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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13. Palanivelu C, Rangarajan M, Annapoorni S, Senthilkumar R, Anand NV: Laparoscopic right hemicolectomy for goblet-cell carcinoid of the appendix: report of a rare case and literature survey. J Laparoendosc Adv Surg Tech A; 2008 Jun;18(3):417-21
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  • [Title] Laparoscopic right hemicolectomy for goblet-cell carcinoid of the appendix: report of a rare case and literature survey.
  • Tumors of the appendix are rare entities, and the majority of them are discovered accidentally during an investigation for other conditions.
  • Laparoscopic surgery for appendiceal goblet-cell carcinoid (GCC) has only been reported once before.
  • Our patient was incidentally discovered to have an appendiceal tumor and was referred to us for laparoscopy.
  • The tumor involved the body of the appendix and was adherent to the cecum.
  • Histopathology confirmed an appendiceal goblet-cell carcinoid.
  • GCC is a rare tumor of the appendix.
  • Hemicolectomy is indicated in specific situations, such as local involvement or tumor size >2 cm.
  • In our patient, the tumor was adherent to the cecum and tumor size was 5 cm.
  • [MeSH-major] Carcinoid Tumor / surgery. Colectomy

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  • (PMID = 18503377.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 18
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14. Yong Jiang, Huawei Liu, Hu Long, Yingying Yang, Dianying Liao, Xiuhui Zhang: Goblet cell carcinoid of the appendix: a clinicopathological and immunohistochemical study of 26 cases from southwest china. Int J Surg Pathol; 2010 Dec;18(6):488-92
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  • [Title] Goblet cell carcinoid of the appendix: a clinicopathological and immunohistochemical study of 26 cases from southwest china.
  • Goblet cell carcinoid (GCC) of the appendix is characterized by a dual differentiation of both endocrine and gland.
  • Follow-up data showed that 1 patient died from peritoneal metastasis and that the other 17 cases survived free of the tumor.
  • The authors characterize GCC as a special low-grade malignant carcinoma with a primary epithelial differentiation and little neuroendocrine differentiation.
  • [MeSH-major] Appendiceal Neoplasms / metabolism. Appendiceal Neoplasms / pathology. Carcinoid Tumor / metabolism. Carcinoid Tumor / pathology
  • [MeSH-minor] Adult. Aged. Animals. Biomarkers, Tumor / analysis. China. Female. Humans. Immunohistochemistry. Male. Middle Aged. Schistosomiasis / complications

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  • (PMID = 20732910.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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15. Gramann T, Matter L, Pfofe D, Flury R, Jaeger P: [Metastazation into the seminal vesicles due to primary goblet cell carcinoid of the vermiform appendix. An unusual diagnostic procedure of a seminal vesicle tumor]. Urologe A; 2009 Nov;48(11):1352-5
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  • [Title] [Metastazation into the seminal vesicles due to primary goblet cell carcinoid of the vermiform appendix. An unusual diagnostic procedure of a seminal vesicle tumor].
  • [Transliterated title] Samenblasenmetastase bei primärem Becherzellkarzinoid der Appendix vermiformis. Ein aussergewöhnlicher Abklärungsgang eines Samenblasentumors.
  • A goblet cell carcinoid of the vermiform appendix was identified as the primary tumor.
  • This case report deals with metastazation of a primary goblet cell carcinoma into the seminal vesicles on both sides as an extremely rare reason for suspicious rectal palpation results.
  • The tumor valency, diagnostic work up, therapy and further differential diagnoses are described.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology. Carcinoid Tumor / secondary. Genital Neoplasms, Male / pathology. Genital Neoplasms, Male / secondary. Seminal Vesicles / pathology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Appendectomy. Appendix / pathology. Biomarkers, Tumor / analysis. Biopsy. Combined Modality Therapy. Diagnosis, Differential. Digital Rectal Examination. Fluorouracil / administration & dosage. Fluorouracil / adverse effects. Humans. Leucovorin / administration & dosage. Leucovorin / adverse effects. Magnetic Resonance Imaging. Male. Middle Aged. Organoplatinum Compounds / administration & dosage. Organoplatinum Compounds / adverse effects. Palliative Care. Patient Care Team. Peritoneal Neoplasms / pathology. Peritoneal Neoplasms / secondary. Synaptophysin / analysis

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  • [Cites] Am J Surg Pathol. 2006 Jun;30(6):694-704 [16723846.001]
  • [Cites] Urologe A. 2008 May;47(5):616-9 [18231770.001]
  • [Cites] Chin Med J (Engl). 2007 Aug 5;120(15):1383-4 [17711752.001]
  • [Cites] Urology. 2002 Sep;60(3):515 [12350506.001]
  • [Cites] Indian J Med Res. 2004 Oct;120(4):305-15 [15520484.001]
  • [Cites] J Gastrointest Surg. 2008 Aug;12(8):1436-8 [18521695.001]
  • [Cites] World J Surg Oncol. 2008 Feb 06;6:15 [18252007.001]
  • [Cites] Gut. 2005 Jun;54 Suppl 4:iv1-16 [15888809.001]
  • [Cites] Cancer. 2003 Feb 15;97(4):934-59 [12569593.001]
  • [Cites] N Engl J Med. 1999 Mar 18;340(11):858-68 [10080850.001]
  • [Cites] Int J Surg. 2007 Oct;5(5):345-50 [17561465.001]
  • [Cites] Int J Urol. 2004 Apr;11(4):253-5 [15028108.001]
  • [Cites] Surgeon. 2008 Oct;6(5):266-72 [18939372.001]
  • [Cites] J Urol. 2002 Nov;168(5):1891-6 [12394673.001]
  • [Cites] Aktuelle Urol. 2008 Jan;39(1):71-3 [18228193.001]
  • [Cites] Ann Surg. 1999 Jun;229(6):815-21; discussion 822-3 [10363895.001]
  • (PMID = 19705095.001).
  • [ISSN] 1433-0563
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Organoplatinum Compounds; 0 / Synaptophysin; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Folfox protocol
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16. Byrn JC, Wang JL, Divino CM, Nguyen SQ, Warner RR: Management of goblet cell carcinoid. J Surg Oncol; 2006 Oct 1;94(5):396-402
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of goblet cell carcinoid.
  • BACKGROUND AND OBJECTIVES: Goblet cell carcinoid, a rare tumor of intermediate malignant potential, is known to account for a significant minority of appendiceal neoplasms.
  • Sixteen new cases of gastrointestinal goblet cell carcinoid were reviewed to describe their presentation, treatment, and outcome.
  • RESULTS: Sixteen patients were diagnosed with goblet cell carcinoid between 1995 and 2005.
  • Patients were divided into two groups: those where the diagnosis was an incidental finding at operation (Group 1) and those where the presentation was of an abdominal mass or metastatic disease (Group 2).
  • CONCLUSIONS: Goblet cell carcinoid is a rare malignant tumor largely affecting the appendix.
  • In patients presenting with appendicitis, our series does not support the recommendation of right hemicolectomy based on pathologic diagnosis alone and surgical intervention must be customized to the individual patient.
  • [MeSH-major] Appendiceal Neoplasms / therapy. Carcinoid Tumor / therapy. Gastrointestinal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Appendectomy. Appendicitis / complications. Appendicitis / surgery. Colectomy. Female. Humans. Incidental Findings. Liver Neoplasms / diagnosis. Male. Middle Aged. Ovarian Neoplasms / diagnosis. Retrospective Studies. Uterine Neoplasms / diagnosis

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  • [Copyright] Copyright (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16967437.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Knigge U, Hansen CP: [Appendiceal carcinoid tumors and goblet cell carcinoids]. Ugeskr Laeger; 2010 May 31;172(22):1678-81
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  • [Title] [Appendiceal carcinoid tumors and goblet cell carcinoids].
  • [Transliterated title] Karcinoide tumorer og gobletcelle-karcinoide tumorer i appendix.
  • Appendiceial carcinoid tumors (CAT) and goblet cell carcinoids (GCCAT) are rare.
  • [MeSH-major] Appendiceal Neoplasms. Carcinoid Tumor. Goblet Cells

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  • (PMID = 20525467.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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18. Chetty R, Serra S: Lipid-rich and clear cell neuroendocrine tumors ("carcinoids") of the appendix: potential confusion with goblet cell carcinoid. Am J Surg Pathol; 2010 Mar;34(3):401-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lipid-rich and clear cell neuroendocrine tumors ("carcinoids") of the appendix: potential confusion with goblet cell carcinoid.
  • The so-called clear cell change has been described in neuroendocrine tumors at several locations.
  • However, lipid has not been demonstrated in all cases of clear cell carcinoid tumors.
  • Such variants have not been described in carcinoid tumors of the appendix and cases with a prominent proportion of clear or more correctly, lipid-rich cytoplasm may bear a superficial resemblance to goblet cell carcinoid and/or signet ring adenocarcinoma.
  • Seven cases, in 5 females and 2 males ranging in age from 22 to 65 years, were noted to have a population of lipid-rich and vacuolated clear cells accounting for 25% or more of the tumor population.
  • The carcinoid tumors were incidental in all cases with 4 of patients presenting with appendicitis, 2 with concomitant mucinous cystadenocarcinomas of the appendix and 1 with an adenocarcinoma of the ascending colon.
  • The importance of recognizing this variant of carcinoid tumor in the appendix is to avoid confusion with goblet cell carcinoid tumors with or without a signet ring adenocarcinoma.
  • The presence of multi-vacuolated, foamy and clear cells, some resembling signet ring or goblet cells, in otherwise classic carcinoid tumors is rare but should be considered in this context in the appendix.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology. Lipids / analysis
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Cytoplasm / chemistry. Cytoplasm / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Incidental Findings. Male. Middle Aged. Prognosis. Vacuoles / chemistry. Vacuoles / pathology. Young Adult

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  • (PMID = 20139759.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Lipids
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19. Ng SC, Noursadeghi M, von Herbay A, Vaizey C, Pitcher MC, Flanagan KL: Cytomegalovirus ileitis associated with goblet cell carcinoid tumour of the appendix. J Infect; 2007 Mar;54(3):e153-6
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  • [Title] Cytomegalovirus ileitis associated with goblet cell carcinoid tumour of the appendix.
  • We report a female patient with cytomegalovirus (CMV) terminal ileitis and CMV viraemia, associated with a metastatic goblet cell carcinoid (GCC) tumour of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / complications. Carcinoid Tumor / complications. Cytomegalovirus / isolation & purification. Cytomegalovirus Infections / complications. Ileitis / complications. Ileitis / virology

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  • (PMID = 17049463.001).
  • [ISSN] 1532-2742
  • [Journal-full-title] The Journal of infection
  • [ISO-abbreviation] J. Infect.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antiviral Agents; P9G3CKZ4P5 / Ganciclovir
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20. Koopmans NG, Kwee HW, Heemskerk J: [Acute appendicitis with goblet cell carcinoid]. Ned Tijdschr Geneeskd; 2010;154:A1154
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  • [Title] [Acute appendicitis with goblet cell carcinoid].
  • The patient underwent an appendicectomy of the inflamed appendix with periappendicular infiltrate.
  • However, histological examination revealed a small goblet cell carcinoid, histological group C, with acute inflammation.
  • Several tumour cells were present in a lymph duct at the appendix base.
  • Without histological examination such a rare diagnosis can easily be missed.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Appendicitis / diagnosis. Carcinoid Tumor / diagnosis

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  • (PMID = 20619032.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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21. Tang LH, Shia J, Soslow RA, Dhall D, Wong WD, O'Reilly E, Qin J, Paty P, Weiser MR, Guillem J, Temple L, Sobin LH, Klimstra DS: Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix. Am J Surg Pathol; 2008 Oct;32(10):1429-43
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  • [Title] Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix.
  • Previously, such lesions have been variously designated as adenocarcinoid, goblet cell carcinoid (GCC), and mixed adenocarcinoma carcinoid.
  • In this study, we undertook a retrospective investigation of 63 such cases and classified them as typical GCC (group A) and adenocarcinoma ex GCC on the basis of the histologic features of the tumor at the primary site.
  • The adenocarcinoma ex GCC group was further divided into signet ring cell type (group B) and poorly differentiated adenocarcinoma type (group C).
  • The clinical characteristics and prognosis were compared within these groups and with conventional de novo appendiceal adenocarcinomas.
  • They display a spectrum of histologic features and possess the potential to transform to an adenocarcinoma phenotype of either signet ring cell or poorly differentiated adenocarcinoma types.
  • Careful evaluation of the morphologic features of GCCs and appropriate pathologic classification are crucial for clinical management and prediction of outcome.
  • Surgical management with right hemicolectomy is recommended after appendectomy for most cases, particularly those with an adenocarcinoma component (groups B and C).
  • [MeSH-major] Adenocarcinoma / pathology. Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology. Carcinoma, Signet Ring Cell / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antineoplastic Agents / therapeutic use. Appendectomy. Cell Differentiation. Cell Proliferation. Chemotherapy, Adjuvant. Colectomy. Disease-Free Survival. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Staging. Observer Variation. Retrospective Studies. Terminology as Topic. Time Factors. Treatment Outcome

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  • [CommentIn] Am J Surg Pathol. 2009 Aug;33(8):1259-60; author reply 1260-1 [19471156.001]
  • (PMID = 18685490.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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22. Nogales FF, Buriticá C, Regauer S, González T: Mucinous carcinoid as an unusual manifestation of endodermal differentiation in ovarian yolk sac tumors. Am J Surg Pathol; 2005 Sep;29(9):1247-51
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  • [Title] Mucinous carcinoid as an unusual manifestation of endodermal differentiation in ovarian yolk sac tumors.
  • We present, for the first time, two yolk sac tumors (YST) in women 37 and 18 years of age, one with a typical parietovisceral pattern and the other with a glandular pattern, which were associated with extensive areas of mucinous carcinoid (MC).
  • The tumor in the first case had numerous nodules of tubulopapillary YST that merged with well-differentiated MC.
  • The tumor in the second case consisted of an AFP-positive glandular YST, with a glandulopapillary pattern closely resembling fetal lung type adenocarcinoma, coexisting with an AFP-negative, cytokeratin 20-positive, atypical MC; transitional areas between the two components were also seen.
  • The patient died 1 year after diagnosis.
  • It is important to differentiate the yolk sac and carcinoid components due to their different responses to chemotherapy and to evaluate the possibility of mucinous carcinoid developing into a highly aggressive carcinoma.
  • [MeSH-major] Carcinoid Tumor / pathology. Endodermal Sinus Tumor / pathology. Ovarian Neoplasms / drug therapy

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  • (PMID = 16096416.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / alpha-Fetoproteins
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23. Alsaad KO, Serra S, Schmitt A, Perren A, Chetty R: Cytokeratins 7 and 20 immunoexpression profile in goblet cell and classical carcinoids of appendix. Endocr Pathol; 2007;18(1):16-22
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  • [Title] Cytokeratins 7 and 20 immunoexpression profile in goblet cell and classical carcinoids of appendix.
  • Goblet cell carcinoid (GCC) of the vermiform appendix is an uncommon neoplasm and its histogenesis is controversial.
  • Whether GCC represents a morphological variant of classical appendiceal carcinoid or a mucin-producing adenocarcinoma is still conjectural.
  • In this study, we compared the expression of CK7 and CK20 in 17 cases of appendiceal GCC and 25 cases of classical carcinoid.
  • The tumors were also evaluated for Ki-67 proliferation index, mitotic activity, tumor necrosis, extracellular pools of mucin, obvious intestinal type adenocarcinomatous foci, angiolymphatic permeation, perineural/neural infiltration, and the depth of invasion of the appendix wall.
  • Immunohistochemically, all 17 (100%) of GCC exhibited strong and diffuse immunopositivity for CK20, whereas expression of CK7 was present in 12 cases (70.5%), ranging from 5 to 50% of tumor cells being labeled.
  • On the other hand, 25 cases of classical carcinoid tumors were consistently negative for CK7; however, 4 cases (16%) showed immunolabeling for CK20 in 25-50% of the tumor cells.
  • The Ki-67 labeling index in classical carcinoids ranged from 0 to 5%.
  • This study shows that in addition to the morphological differences, GCC (CK7/CK20-positive) and classical carcinoid (CK7/CK20-negative) differ in their expression of CK7 and CK20.
  • In addition, GCC shows the same CK7/CK20 immunoexpression as colorectal adenocarcinoma.
  • Goblet cell carcinoid should be regarded as a crypt cell or an amphicrine carcinoma rather than a variant of carcinoid tumor, a lesion that has benign connotations.
  • [MeSH-major] Appendiceal Neoplasms / metabolism. Carcinoid Tumor / metabolism. Goblet Cells / metabolism. Keratin-20 / metabolism. Keratin-7 / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Cell Proliferation. Female. Humans. Immunohistochemistry. Ki-67 Antigen / metabolism. Male. Middle Aged. Treatment Outcome

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  • (PMID = 17652796.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-20; 0 / Keratin-7; 0 / Ki-67 Antigen
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24. Zafar S, Chen H, Sun W, Das K: Cytology of metastatic appendiceal goblet cell carcinoid in pleural effusion fluid: a case report. Diagn Cytopathol; 2008 Dec;36(12):894-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytology of metastatic appendiceal goblet cell carcinoid in pleural effusion fluid: a case report.
  • Goblet cell appendiceal carcinoid (GCAC) is a rare neoplasm.
  • We described the case of a 72-year-old man who presented with symptoms related to ascites.
  • A computed tomography (CT) scan showed a mass involving the base of the appendix, ascites and concomitant pleural effusion.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Carcinoid Tumor / diagnosis. Pleural Effusion, Malignant / diagnosis
  • [MeSH-minor] Aged. Ascites / diagnosis. Ascites / etiology. Diagnosis, Differential. Humans. Male

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18855885.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Volante M, Righi L, Asioli S, Bussolati G, Papotti M: Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasms. Virchows Arch; 2007 Aug;451 Suppl 1:S61-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasms.
  • Within the spectrum of neuroendocrine tumors arising in different organs, intermediate and controversial entities exist displaying a coexistence of neuroendocrine and nonneuroendocrine cell populations, and that are grouped under terms such as "goblet cell carcinoid", "mixed endocrine-exocrine carcinoma", "combined carcinomas", or "adenocarcinoma with neuroendocrine differentiation".
  • These tumors may display variable amounts of the two components, potentially ranging from 1 to 99%, and variable structural patterns, ranging from single scattered neuroendocrine cells to a well-defined neuroendocrine tumor cell component organized in typical organoid, trabecular, or solid growth patterns.
  • Although variably included in the site-specific World Health Organization classification schemes, clear definitions and diagnostic features are still missing, as well as a definite knowledge of their biological properties and histogenesis.
  • In the present report, the main characteristics of tumors showing mixed neuroendocrine and nonneuroendocrine features will be described, using morphological patterns and site of origin as schematic guidelines.
  • [MeSH-major] Carcinoid Tumor / pathology

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  • (PMID = 17684764.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Number-of-references] 77
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26. Wang HL, Dhall D: Goblet or signet ring cells: that is the question. Adv Anat Pathol; 2009 Jul;16(4):247-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet or signet ring cells: that is the question.
  • Goblet cell carcinoid tumor is a rare mixed endocrine-exocrine neoplasm of the appendix.
  • It carries an intermediate biologic behavior between a classic carcinoid tumor and a conventional adenocarcinoma.
  • A recent retrospective study of a large number of appendiceal goblet cell carcinoids has shown that these tumors can be stratified into 3 subgroups based on careful histologic analysis: typical goblet cell carcinoid (group A); adenocarcinoma ex goblet cell carcinoid, signet ring cell type (group B); and adenocarcinoma ex goblet cell carcinoid, poorly differentiated carcinoma type (group C).
  • Thus, meticulous histologic evaluation is of critical importance in determining the prognosis and guiding the management of patients with goblet cell carcinoids.
  • [MeSH-major] Adenocarcinoma / pathology. Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology. Carcinoma, Signet Ring Cell / pathology. Goblet Cells / pathology
  • [MeSH-minor] Adult. Aged. Appendectomy. Cell Differentiation. Female. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 19546612.001).
  • [ISSN] 1533-4031
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 11
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27. Coşkun H, Bostanci O, Dilege ME, Mihmanli M, Yilmaz B, Akgün I, Yildirim S: Carcinoid tumors of appendix: treatment and outcome. Ulus Travma Acil Cerrahi Derg; 2006 Apr;12(2):150-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoid tumors of appendix: treatment and outcome.
  • BACKGROUND: The aim of this study is to evaluate the clinical and histopathological features and the treatment of carcinoid tumors of the appendix.
  • METHODS: A retrospective review of medical records and pathology specimens of patients with carcinoid tumor of the appendix has been done.
  • RESULTS: The histopathological examination of the appendices revealed carcinoid tumor in 11 out of 6777 (0.16%) patients operated for acute appendicitis.
  • The tumor was localized in the distal 1/3 region in 10 patients and in the proximal 1/3 region in 1 patient.
  • The mean tumor diameter was 0.73+/-0.36 cm (0.3-1.5).
  • Ten patients had classical type carcinoid tumor whereas goblet cell carcinoid tumor was only seen in one patient.
  • [MeSH-major] Appendiceal Neoplasms / epidemiology. Appendiceal Neoplasms / surgery. Carcinoid Tumor / epidemiology. Carcinoid Tumor / surgery

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  • (PMID = 16676255.001).
  • [ISSN] 1306-696X
  • [Journal-full-title] Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
  • [ISO-abbreviation] Ulus Travma Acil Cerrahi Derg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
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28. Tang LH: Epithelial neoplasms of the appendix. Arch Pathol Lab Med; 2010 Nov;134(11):1612-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelial neoplasms of the appendix.
  • CONTEXT: The appendix gives rise to an array of epithelial neoplasms showing glandular or neuroendocrine differentiation, and some tumors with elements of both cell types.
  • Although some appendiceal neoplasms resemble their counterparts in the small and large intestines (conventional adenocarcinoma and carcinoid tumor), the appendix also gives rise to relatively unique entities including mucinous neoplasms and goblet cell carcinoid tumors, which present a challenge in pathologic classification and clinical management.
  • OBJECTIVE: To review clinical and diagnostic issues for 3 pathologic types of epithelial neoplasms of the appendix:.
  • (1) adenocarcinoma, with specific focus on mucinous neoplasm;.
  • (2) goblet cell carcinoid tumor and associated adenocarcinoma; and (3) typical carcinoid tumor.
  • CONCLUSIONS: The most important issue in pathologic assessment of epithelial tumors of the appendix is to understand the clinical implications inherent in the diagnosis.
  • [MeSH-major] Adenocarcinoma / pathology. Appendiceal Neoplasms / pathology. Appendix / pathology. Carcinoid Tumor / pathology

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  • (PMID = 21043814.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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29. Stinner B, Rothmund M: Neuroendocrine tumours (carcinoids) of the appendix. Best Pract Res Clin Gastroenterol; 2005 Oct;19(5):729-38
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  • [Title] Neuroendocrine tumours (carcinoids) of the appendix.
  • Neuroendocrine tumours (NETs) of the appendix (formerly 'carcinoids') are rare and are usually detected incidentally after appendectomy.
  • Histopathologically they derive from a subepithelial cell population, which is different from NETs in other sites.
  • They are preferentially located at the tip of the appendix.
  • Tumours >2 cm require right hemicolectomy because of a significant risk of metastatic spread.
  • Treatment for lesions 1-2 cm is controversial and needs further characterization of the tumour (i.e. mesoappendiceal invasion, vascular invasion, mitotic activity, proliferation markers) and careful patient risk evaluation.
  • Goblet-cell carcinoids have features resembling both carcinoid and adenocarcinoma and should be treated by hemicolectomy.
  • [MeSH-major] Appendectomy / methods. Appendiceal Neoplasms / pathology. Appendiceal Neoplasms / surgery. Carcinoid Tumor / pathology. Carcinoid Tumor / surgery. Neoplasm Invasiveness / pathology

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  • (PMID = 16253897.001).
  • [ISSN] 1521-6918
  • [Journal-full-title] Best practice & research. Clinical gastroenterology
  • [ISO-abbreviation] Best Pract Res Clin Gastroenterol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 32
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30. Basic-Jukic N, Furic-Cunko V, Coric M, Bubic-Filipi LJ, Kastelan Z, Pasini J, Kes P: Appendiceal carcinoid and mucinous cystadenoma in renal transplant recipients: case reports. Transplant Proc; 2010 Jun;42(5):1704-7
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  • [Title] Appendiceal carcinoid and mucinous cystadenoma in renal transplant recipients: case reports.
  • Carcinoids are rare neuroendocrine tumors that arise from the enterochromaffin cells.
  • Although appendiceal carcinoid tumors are the commonest malignant neoplasms affecting the appendix, and mucinous cystadenoma is the commonest benign appendiceal neoplasm, they have not been reported in immunosuppressed patients.
  • We present two renal transplant recipients who developed combined appendiceal carcinoid and mucinous cystadenoma.
  • [MeSH-major] Appendiceal Neoplasms / etiology. Cystadenoma, Mucinous / etiology. Kidney Transplantation / adverse effects

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  • (PMID = 20620505.001).
  • [ISSN] 1873-2623
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Hristov AC, Young RH, Vang R, Yemelyanova AV, Seidman JD, Ronnett BM: Ovarian metastases of appendiceal tumors with goblet cell carcinoidlike and signet ring cell patterns: a report of 30 cases. Am J Surg Pathol; 2007 Oct;31(10):1502-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ovarian metastases of appendiceal tumors with goblet cell carcinoidlike and signet ring cell patterns: a report of 30 cases.
  • Synchronous and metachronous ovarian and appendiceal mucinous tumors are often the subject of diagnostic consultations in gynecologic pathology practices to address whether the tumors are independent neoplasms or related as primary and metastasis.
  • Those with goblet cell carcinoidlike patterns have not been extensively evaluated in a large series.
  • The appendices were often firm or thickened but usually did not have a discrete measurable tumor and were not notably enlarged; microscopically, transmural invasion was present in all of them.
  • The ovarian and appendiceal tumors exhibited a variety of patterns of differentiation, including signet ring cell and glandular, with all displaying some goblet cell carcinoidlike patterns (nests, islands, cords, or cryptlike tubules with goblet cells); teratomatous elements were not identified in any ovarian tumors.
  • The clinicopathologic features of these ovarian tumors indicate they should be labeled as metastatic appendiceal adenocarcinomas rather than as goblet cell carcinoid tumors both to reflect their behavior and help distinguish them from the rare true primary ovarian goblet cell carcinoid tumors.
  • In cases in which the primary tumor is not already evident, their "goblet cell carcinoidlike" patterns should direct attention to the appendix as a possible source.
  • [MeSH-major] Adenocarcinoma / secondary. Appendiceal Neoplasms / pathology. Carcinoid Tumor / secondary. Carcinoma, Signet Ring Cell / secondary. Ovarian Neoplasms / secondary
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Chromogranins / metabolism. Female. Humans. Middle Aged. Survival Rate. Synaptophysin / metabolism

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  • (PMID = 17895750.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromogranins; 0 / Synaptophysin
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32. Toumpanakis C, Standish RA, Baishnab E, Winslet MC, Caplin ME: Goblet cell carcinoid tumors (adenocarcinoid) of the appendix. Dis Colon Rectum; 2007 Mar;50(3):315-22
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  • [Title] Goblet cell carcinoid tumors (adenocarcinoid) of the appendix.
  • PURPOSE: Goblet cell appendiceal carcinoids represent rare tumors that exhibit histologic features of both adenocarcinomas and neuroendocrine tumors.
  • We present the long-term results of a series of 15 patients, focusing on clinical manifestations, diagnosis, and management.
  • Final diagnosis was confirmed by histology.
  • Three patients had metastases at previous diagnosis.
  • Ki67 index was greater than 20 percent in all of them, while in only one with local tumor.
  • Twelve patients are alive, while three died of their disease 9, 13, and 14 months after diagnosis.
  • Ki67 index appears to predict tumor behavior.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Carcinoid Tumor / diagnosis
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Appendectomy. Biomarkers, Tumor / analysis. Cisplatin / administration & dosage. Colectomy. Combined Modality Therapy. Diagnosis, Differential. Etoposide / administration & dosage. Female. Fluorouracil / administration & dosage. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Male. Middle Aged. Neoplasm Metastasis. Retrospective Studies. Streptozocin / administration & dosage

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  • (PMID = 17195086.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 5W494URQ81 / Streptozocin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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33. Deschamps L, Couvelard A: Endocrine tumors of the appendix: a pathologic review. Arch Pathol Lab Med; 2010 Jun;134(6):871-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endocrine tumors of the appendix: a pathologic review.
  • CONTEXT: Although rare, appendiceal endocrine tumors are the most common neoplasms of the appendix.
  • OBJECTIVE: To provide recent data that focus on the pathology of endocrine tumors of the appendix including classifications and guidelines for patient management.
  • CONCLUSIONS: Appendiceal endocrine tumors are separated into 2 main groups: classic endocrine tumors and goblet cell carcinoids.
  • Evaluation of their prognoses and risks of malignancy, according to these classifications, depends on several parameters including tumor size, proliferation rate, and infiltration of appendiceal wall and mesoappendix.
  • Most patients with classic endocrine tumors of the appendix have a favorable prognosis.
  • In contrast, in patients presenting with a goblet cell carcinoid, a right hemicolectomy after the initial appendectomy is considered the standard surgical intervention.
  • [MeSH-minor] Appendectomy. Carcinoid Tumor / classification. Carcinoid Tumor / diagnosis. Carcinoid Tumor / pathology. Colectomy. Humans. Prognosis. World Health Organization

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  • (PMID = 20524865.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 41
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34. La Rosa S, Finzi G, Puppa G, Capella C: Lipid-rich variant of appendiceal well-differentiated endocrine tumor (carcinoid). Am J Clin Pathol; 2010 May;133(5):809-14
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  • [Title] Lipid-rich variant of appendiceal well-differentiated endocrine tumor (carcinoid).
  • Well-differentiated endocrine tumors (WDETs) of the appendix show characteristic morphologic features, including proliferation of cells with finely granulated eosinophilic cytoplasm.
  • However, clear cell WDETs, which can present a diagnostic challenge, have been occasionally described, but it is unknown whether they represent a morphologic variant with distinct clinicopathologic features.
  • Moreover, the clear cell appearance of the cytoplasm has never been explained.
  • These neoplasms, which represent a lipid-rich variant of appendiceal WDETs, do not have different relevant clinical implications compared with conventional WDETs, but it is important to know of their existence for the differential diagnosis with more aggressive neoplasms, including goblet cell carcinoids and appendiceal metastases from clear cell carcinomas.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology. Lipids / analysis
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / analysis. Cell Proliferation. Child. Cytoplasm / chemistry. Cytoplasm / ultrastructure. Disease-Free Survival. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Young Adult

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  • (PMID = 20395531.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Lipids
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35. Alsaad KO, Serra S, Perren A, Hsieh E, Chetty R: CK19 and CD99 immunoexpression profile in goblet cell (mucin-producing neuroendocrine tumors) and classical carcinoids of the vermiform appendix. Int J Surg Pathol; 2007 Jul;15(3):252-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CK19 and CD99 immunoexpression profile in goblet cell (mucin-producing neuroendocrine tumors) and classical carcinoids of the vermiform appendix.
  • The purpose of this study was to explore CK19 and CD99 immunostaining in mucin-producing neuroendocrine (goblet cell) and classical carcinoids of the appendix.
  • Eighteen goblet cell carcinoids (GCCs) and 20 classic carcinoids were stained with CK19, CD99, and Ki-67, and these results were correlated with known pathological features of aggression: extent of invasion, mitoses, necrosis, and histological pattern.
  • All 18 GCCs were CK19 strongly positive, whereas 16/20 classic carcinoids were also CK19 positive.
  • Fourteen of 18 GCCs and 14/20 classic carcinoids were CD99 positive.
  • CK19/CD99 immunoexpression did not correlate with extent of tumor invasion and mesoappendiceal extension, mitotic activity, Ki-67 labeling index, presence of extracellular mucinous pools dissecting muscle, and angiolymphatic and perineural/neural invasion.
  • There is no difference in the immunostaining for CK19 and CD99 between GCCs and classic carcinoids, and both types of neuroendocrine tumor show the same extent of expression of both markers.
  • [MeSH-major] Antigens, CD / metabolism. Appendiceal Neoplasms / metabolism. Carcinoid Tumor / metabolism. Cell Adhesion Molecules / metabolism. Keratin-19 / metabolism
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Cell Proliferation. Gene Expression Regulation, Neoplastic. Humans. Neoplasm Invasiveness / pathology

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  • (PMID = 17652531.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Keratin-19
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36. Fujiyoshi Y, Kuhara H, Eimoto T: Composite glandular-endocrine cell carcinoma of the stomach. Report of two cases with goblet cell carcinoid component. Pathol Res Pract; 2005;200(11-12):823-9
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  • [Title] Composite glandular-endocrine cell carcinoma of the stomach. Report of two cases with goblet cell carcinoid component.
  • Composite glandular-endocrine cell carcinoma (CGECC) is recognized as a special type of gastric tumor composed of ordinary adenocarcinoma and neuroendocrine tumors.
  • Goblet cell carcinoid (GCC) is a well-established type of appendiceal carcinoid, but the GCC component has not been well delineated in CGECC of the stomach.
  • On initial biopsy, both cases were diagnosed as signet-ring cell carcinoma.
  • However, the resected tumors consisted of three components: signet-ring cell carcinoma, GCC, and glandular adenocarcinoma.
  • Although some signet-ring carcinoma cells and goblet carcinoid cells were indistinguishable by hematoxylin and eosin staining, E-cadherin immunostaining disclosed a definitive difference regarding the staining pattern in these cells.
  • Both patients are well, with no recurrent tumor for about 10 years of follow-up.
  • CGECC with a GCC component may have been confused with conventional adenocarcinoma with signet-ring cells.
  • In cases of advanced signet-ring cell carcinoma with good prognosis, the possibility of such CGECC has to be considered.
  • [MeSH-major] Carcinoid Tumor / pathology. Carcinoma, Signet Ring Cell / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Cadherins / metabolism. Female. Humans. Immunohistochemistry. Male. Neoplasms, Second Primary. Treatment Outcome


37. Bucher P, Gervaz P, Ris F, Oulhaci W, Egger JF, Morel P: Surgical treatment of appendiceal adenocarcinoid (goblet cell carcinoid). World J Surg; 2005 Nov;29(11):1436-9
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  • [Title] Surgical treatment of appendiceal adenocarcinoid (goblet cell carcinoid).
  • Adenocarcinoid of the appendix is an infrequent tumor with histologic features of both adenocarcinoma and carcinoid tumor.
  • Although its malignant potential remains unclear, adenocarcinoids seem to be biologically more aggressive than conventional carcinoids.
  • The aim of this study was to analyze long-term results of surgical treatment for appendiceal adenocarcinoid.
  • A retrospective review (1991-2003) identified seven patients (median age 72, range 27-81 years) treated for appendiceal adenocarcinoid.
  • Indications for colectomy were tumor size (three cases) associated with appendectomy margin invasion in one case.
  • One patient subsequently died of colon carcinoma 6 years after adenocarcinoid treatment.
  • Our results suggest that appendectomy alone could be used for appendiceal adenocarcinoid provided that the tumor (1) is less than 1 cm;.
  • (2) does not extend beyond the appendix adventitia;.
  • (3) has less than 2 mitoses/10 high power fields; and (4) has surgical margins that are tumor free.
  • The risk for developing colorectal adenocarcinoma seems to be extremely high in patients treated for appendiceal adenocarcinoid and warrants close follow-up with colonoscopic screening.
  • [MeSH-major] Appendectomy. Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery

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  • (PMID = 16136284.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Pham TH, Wolff B, Abraham SC, Drelichman E: Surgical and chemotherapy treatment outcomes of goblet cell carcinoid: a tertiary cancer center experience. Ann Surg Oncol; 2006 Mar;13(3):370-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical and chemotherapy treatment outcomes of goblet cell carcinoid: a tertiary cancer center experience.
  • BACKGROUND: Goblet cell carcinoid (GCC) is a rare malignant tumor with distinct histological and clinical features.
  • RESULTS: The age at diagnosis (mean +/- SE) was 55 +/- 13 years.
  • [MeSH-major] Appendectomy. Appendiceal Neoplasms / drug therapy. Appendiceal Neoplasms / surgery. Carcinoid Tumor / drug therapy. Carcinoid Tumor / surgery

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  • (PMID = 16485156.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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39. O'Donnell ME, Carson J, Garstin WI: Surgical treatment of malignant carcinoid tumours of the appendix. Int J Clin Pract; 2007 Mar;61(3):431-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of malignant carcinoid tumours of the appendix.
  • Since their first description in 1882, malignant neoplasms of the appendix still remain rare.
  • Malignant carcinoid tumours are the most common accounting for 85% of all appendiceal neoplasms.
  • Preoperative diagnosis is invariably difficult, and precise treatment protocols for these neoplasms remain unclear.
  • A retrospective review of all malignant carcinoid tumours diagnosed in our hospital between April 1994 and December 2003 was performed.
  • Nine patients were identified with classical carcinoid tumours (CCT); (M = 3 and F = 6, mean age: 43, range 14-81) and two patients with goblet-cell morphology (F = 2, age 46 and 76).
  • From our experience and subsequent review of the literature, we recommend right hemicolectomy as the treatment of choice for malignant carcinoid tumours.
  • However, small CCTs less than 2 cm in diameter at the tip of the appendix, with a low proliferative index, without angiolymphatic or mesoappendiceal extension can be treated by appendicectomy.
  • [MeSH-major] Appendectomy / methods. Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery. Colectomy / methods

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  • (PMID = 16911574.001).
  • [ISSN] 1368-5031
  • [Journal-full-title] International journal of clinical practice
  • [ISO-abbreviation] Int. J. Clin. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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40. Gao Z, Kahn L, Bhuiya T: Thymic carcinoid with mucinous stroma: a rare variant of carcinoid with an aggressive clinical course. Ann Diagn Pathol; 2006 Apr;10(2):114-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thymic carcinoid with mucinous stroma: a rare variant of carcinoid with an aggressive clinical course.
  • One variant of thymic carcinoid has prominent mucinous stroma first reported in 1995.
  • We describe such a case characterized by abundant stromal mucin resulting in a histologic picture resembling of metastatic mucinous adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / pathology. Carcinoid Tumor / pathology. Mediastinal Neoplasms / pathology. Mucins / metabolism. Thymus Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 16546049.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucins
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41. Louthan O: [Neuroendocrine tumours of the appendix]. Vnitr Lek; 2009 Nov;55(11):1051-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Neuroendocrine tumours of the appendix].
  • According to WHO, neuroendocrine tumors of the appendix (appendiceal carcinoids) are defined as 1. well-differentiated endocrine tumors with benign or uncertain behavior, 2. well-differentiated endocrine carcinoma and 3. goblet cell carcinoma.
  • Carcinoid syndrome is rare in appendiceal carcinoid.
  • Tumor size greater than 2 cm is the most important parameter for prognosis.

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  • (PMID = 20017436.001).
  • [ISSN] 0042-773X
  • [Journal-full-title] Vnitr̆ní lékar̆ství
  • [ISO-abbreviation] Vnitr Lek
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Czech Republic
  • [Number-of-references] 26
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42. Ihtiyar E, Paşaoğlu O, Erkasap S, Karakaş BR, Yaşar FN: Perforated mixed carcinoid-adenocarcinoma in transverse colon and at gastroenterostomy site: case report. World J Surg Oncol; 2010;8:110
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Perforated mixed carcinoid-adenocarcinoma in transverse colon and at gastroenterostomy site: case report.
  • Goblet cell carcinoid of the large intestine is a rare neoplasm, usually located in ascending colon and rectum.
  • A 60-year-old male patient underwent surgery after the diagnosis of acute abdomen.
  • Exploratory laparotomy revealed perforation with a diameter of 1 cm at the site of the previously performed gastroenterostomy and dilatation of the right colic flexure, secondary to a solid obstructive mass located in the mid-portion of transverse colon.
  • Histopathological investigation of the biopsies, taken from the gastroenterostomy site and the tumor, revealed mixed carcinoid-adenocarcinoma with carcinoid component, predominantly composed of goblet cells.
  • Our aim with this paper is to point out that more cases should be reported for more effective diagnosis, histopathological study, clinical investigation, treatment and prognosis of this specific neoplasm.
  • [MeSH-major] Carcinoid Tumor / pathology. Colonic Neoplasms / pathology. Gastroenterostomy. Intestinal Perforation / pathology
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / pathology. Adenocarcinoma / surgery. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colon, Transverse / pathology. Combined Modality Therapy. Fluorouracil / therapeutic use. Humans. Laparotomy. Leucovorin / therapeutic use. Male. Middle Aged. Organoplatinum Compounds / therapeutic use. Prognosis

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  • [Cites] Pathol Int. 2003 Jul;53(7):457-62 [12828611.001]
  • [Cites] Am J Surg Pathol. 1988 Aug;12(8):607-11 [3400791.001]
  • [Cites] Cancer. 1974 Aug;34(2):338-44 [4852178.001]
  • (PMID = 21176192.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Adenocarcinoid tumor; Folfox protocol
  • [Other-IDs] NLM/ PMC3014938
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43. McGory ML, Maggard MA, Kang H, O'Connell JB, Ko CY: Malignancies of the appendix: beyond case series reports. Dis Colon Rectum; 2005 Dec;48(12):2264-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignancies of the appendix: beyond case series reports.
  • METHODS: All patients diagnosed with mucinous adenocarcinoma (n = 951), adenocarcinoma (n = 646), carcinoid (n = 435), goblet (n = 369), and signet-ring cell (n = 113) in the Surveillance, Epidemiology, and End Results database (1973-2001) were analyzed.
  • The appropriateness of the operative procedure (i.e. , appendectomy vs. colectomy) was examined by tumor type and size.
  • RESULTS: Tumor incidence, patient demographics, survival outcomes, and appropriateness of surgery varied significantly among the different appendiceal tumor histologies.
  • The most common appendiceal tumors were mucinous.
  • With regard to patient demographics, carcinoids presented at an earlier mean age of 41 years and 71 percent were female (P < 0.001 for both).
  • Overall five-year survival was highest for carcinoid (83 percent) and lowest for signet ring (18 percent).
  • Although current guidelines specify that a right hemicolectomy (rather than an appendectomy) be performed for all noncarcinoid tumors and carcinoid tumors >2 cm, we found that 30 percent of noncarcinoids underwent appendectomy.
  • Similarly, 28 percent of carcinoids >2 cm under-went appendectomy, which is a lesser resection than is indicated.
  • CONCLUSIONS: This study provides a population-based analysis of epidemiology, tumor characteristics, survival, and quality of care for appendiceal carcinomas.
  • This characterization provides a novel description of the presentation and outcomes for malignancies of the appendix and highlights that a substantial number of patients with appendiceal tumors may not be receiving appropriate surgical resection.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology. Carcinoma, Signet Ring Cell / pathology

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  • (PMID = 16258711.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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44. Weinreb I, Perez-Ordoñez B: Non-small cell neuroendocrine carcinoma of the sinonasal tract and nasopharynx. Report of 2 cases and review of the literature. Head Neck Pathol; 2007 Sep;1(1):21-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-small cell neuroendocrine carcinoma of the sinonasal tract and nasopharynx. Report of 2 cases and review of the literature.
  • Non-small cell neuroendocrine carcinomas (NSNECs) of the sinonasal tract are rare.
  • The first had a tumor involving left ethmoid sinus and nasal cavity and the second, a neoplasm involving nasopharynx, sphenoid sinus, with bilateral involvement of cavernous sinuses.
  • The literature suggests that NSNECs are a heterogenous group of neoplasms with a morphologic spectrum encompassing tumors resembling "atypical carcinoids", neoplasms composed of large cells akin to large cell neuroendocrine carcinomas, and tumors with glandular and goblet cell differentiation reminiscent of "goblet cell carcinoids".
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Combined Modality Therapy. Humans. Male

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  • [Cites] Histopathology. 1995 Jul;27(1):79-82 [7557912.001]
  • [Cites] Hum Pathol. 1998 Aug;29(8):826-32 [9712424.001]
  • [Cites] Cancer. 2004 Dec 1;101(11):2567-73 [15517582.001]
  • [Cites] Neurosurg Focus. 2002 May 15;12(5):e3 [16119901.001]
  • [Cites] J Neurooncol. 2006 Feb;76(3):299-306 [16163447.001]
  • [Cites] Pathol Res Pract. 1984 Jul;178(6):562-9 [6091074.001]
  • [Cites] Laryngoscope. 2000 Oct;110(10 Pt 1):1617-22 [11037813.001]
  • [Cites] Rhinology. 2001 Mar;39(1):52-4 [11340699.001]
  • [Cites] Cancer. 1980 Jan 15;45(2):330-9 [6243246.001]
  • [Cites] Cancer. 1982 Dec 1;50(11):2388-405 [7139532.001]
  • [Cites] Mod Pathol. 1995 May;8(4):421-6 [7567943.001]
  • (PMID = 20614276.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807510
  • [Keywords] NOTNLM ; Carcinoid tumor / Nasal cavity / Neuroendocrine carcinoma / Olfactory neuroblastoma / Paranasal sinuses / Small cell carcinoma
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45. O'Donnell ME, Badger SA, Beattie GC, Carson J, Garstin WI: Malignant neoplasms of the appendix. Int J Colorectal Dis; 2007 Oct;22(10):1239-48

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant neoplasms of the appendix.
  • BACKGROUND: Appendiceal neoplasms, first described in 1882, are still rare, with pre-operative diagnosis invariably difficult.
  • MATERIALS AND METHODS: A retrospective histopathological review of all appendicectomy specimens was completed between April 1994 and December 2003 to identify patients diagnosed with malignant neoplasms.
  • A literature search of the PubMed database was then performed using the medical search headings; appendix, tumour, neoplasm and malignancy.
  • Eleven patients were found to have carcinoid-type tumours, eight patients with adenocarcinomas and three patients with lymphomas.
  • Patients with classical carcinoid tumours (CCT) had better outcomes than patients with the goblet cell carcinoid, adenocarcinoma and lymphoma.
  • CONCLUSIONS: From our own experience and a subsequent review of the literature, we recommend right hemicolectomy as the treatment of choice for all malignant appendiceal neoplasms, except for small CCT less than 2 cm in diameter at the tip of the appendix, with a low proliferative index, without angiolymphatic or mesoappendiceal extension.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Appendiceal Neoplasms / therapy

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  • (PMID = 17447078.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis
  • [Publication-country] Germany
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46. Chatzipantelis P, Mavrogiorgis A, Kairi-Vassilatou E, Pafiti A: Ovarian neoplasm composed of an insular carcinoid tumor and a borderline mucinous cystadenoma arising in a mature cystic teratoma: a case report. Eur J Gynaecol Oncol; 2006;27(6):636-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ovarian neoplasm composed of an insular carcinoid tumor and a borderline mucinous cystadenoma arising in a mature cystic teratoma: a case report.
  • We report the case of a 57-year-old female patient with an ovarian neoplasm of insular carcinoid and mucinous cystadenoma of low malignant potential, arising in a cystic teratoma of the right ovary.
  • [MeSH-major] Carcinoid Tumor / pathology. Cystadenoma, Mucinous / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology
  • [MeSH-minor] Cell Transformation, Neoplastic. Female. Humans. Hysterectomy. Middle Aged. Ovariectomy

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  • (PMID = 17290604.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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47. Gordon R, Burns K, Friedlich M: Goblet cell carcinoid of the appendix. Can J Surg; 2005 Jun;48(3):251-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet cell carcinoid of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery

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  • [Cites] Surg Gynecol Obstet. 1988 Jul;167(1):81-6 [3289135.001]
  • [Cites] Int Surg. 1989 Apr-Jun;74(2):109-10 [2753618.001]
  • [Cites] J Gastroenterol. 1998 Aug;33(4):582-7 [9719248.001]
  • [Cites] Am J Surg. 1994 Dec;168(6):685-7 [7978019.001]
  • [Cites] Am J Clin Pathol. 1990 Jul;94(1):27-35 [2163192.001]
  • (PMID = 16013634.001).
  • [ISSN] 0008-428X
  • [Journal-full-title] Canadian journal of surgery. Journal canadien de chirurgie
  • [ISO-abbreviation] Can J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC3211548
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48. Saqi A, Shaham D, Scognamiglio T, Murray MP, Henschke CI, Yankelevitz D, Vazquez MF: Incidence and cytological features of pulmonary hamartomas indeterminate on CT scan. Cytopathology; 2008 Jun;19(3):185-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Rendering an accurate preoperative diagnosis in these cases can alter management.
  • Cytological features evaluated included the presence of fibromyxoid stroma, bronchioloalveolar cell hyperplasia, fibroadipose tissue, cartilage and smooth muscle.
  • The immediate impression was hamartoma in 13 (72%), carcinoid in one (6%), mucinous bronchioloalveolar carcinoma in two (11%) and non-diagnostic in two (11%).
  • The final diagnosis of hamartoma in cases diagnosed as carcinoid, mucinous bronchioloalaveolar carcinoma and non-diagnostic on immediate impression was rendered following assessment of all cytological material.
  • CONCLUSION: Overall, FNAs are highly reliable for diagnosing hamartomas even when composed principally of undifferentiated mesenchymal fibromyxoid stroma, especially with the aid of all available preparations including Diff-Quik smears, Papanicolaou smears, ThinPreps and cell block material.
  • [MeSH-major] Hamartoma / diagnosis. Hamartoma / epidemiology. Lung Diseases / diagnosis. Lung Diseases / epidemiology. Tomography, X-Ray Computed
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Humans. Incidence. Lung Neoplasms / pathology. Retrospective Studies

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  • (PMID = 17388933.001).
  • [ISSN] 1365-2303
  • [Journal-full-title] Cytopathology : official journal of the British Society for Clinical Cytology
  • [ISO-abbreviation] Cytopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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49. Young RH: From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary. Part II. Adv Anat Pathol; 2007 May;14(3):149-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This is the second of a two-part consideration of metastatic tumors to the ovary.
  • Here, the matter is considered in 16 categories, largely site-specific.
  • The first tumor discussed is gastric carcinoma of intestinal-type whose ovarian manifestations have been the subject of a recent paper which emphasized its differences from the Krukenberg tumor.
  • Coverage of intestinal adenocarcinoma emphasizes the landmark 1987 paper of RH Lash and WR Hart.
  • The section on pancreatic neoplasms reemphasizes the problems caused by metastatic ductal carcinoma, considered primarily in Part I, and discusses less common issues such as spread of neuroendocrine and acinar cell carcinomas.
  • The section on appendiceal neoplasms highlights ovarian spread of diverse tumors ranging from typical intestinal-type adenocarcinoma to signet-ring cell carcinomas with various patterns which in the ovary may prompt diagnoses such as a goblet cell (mucinous) carcinoid tumor, but whose ovarian features place them in the category of a Krukenberg tumor.
  • The diverse problems in differential diagnosis of carcinoid tumor (provoked by nested, acinar, and other patterns, including folliclelike spaces) are then reviewed.
  • The section on lung tumors largely reflects information in a recent paper that small cell carcinoma and adenocarcinoma are the lung cancers that spread to the ovary most commonly.
  • The extremely broad differential diagnosis posed by metastatic malignant melanoma ranging from that of an oxyphilic tumor, to a small cell tumor, to a follicle-forming neoplasm, is then considered.
  • The sections on renal cell carcinoma and other urinary tract neoplasms emphasize the differential diagnosis of metastatic clear cell carcinoma and primary clear cell carcinoma, an issue usually resolvable by an awareness of the various features of the ovarian variant, rarely or never seen in the renal variant.
  • The endometrial stromal tumors are problematic largely because the history of a primary tumor may be remote, in the ovaries the typical growth and vascular pattern of endometrial stromal neoplasms is not always conspicuous, and some endometrial stromal sarcomas in the ovary show sex cordlike patterns of growth.
  • Recent information has indicated that gastrointestinal stromal tumors may rarely have significant ovarian manifestations and if the primary neoplasm is overlooked, the ovarian tumor may be misdiagnosed, usually as an ovarian fibromatous tumor, but potentially as another primary neoplasm.
  • The sections on ovarian spread of uterine carcinomas emphasize the problems owing to cervical adenocarcinomas, which have a greater tendency to involve the ovaries than squamous cell carcinomas and can simulate primary mucinous or endometrioid cancers.
  • The final neoplasms considered are malignant mesothelioma and the desmoplastic small round cell tumor.
  • The microscopic features of malignant mesothelioma are so different from those of primary ovarian carcinoma in most instances that the diagnosis should be readily established on routine microscopic evaluation.
  • The differential diagnosis of the desmoplastic small round cell tumor is more complex because of the greater overlap with the many other small cell malignant tumors that may involve the ovaries primarily or secondarily.
  • However, as pointed out in brief concluding remarks, despite the aid of that modality, as in surgical pathology overall, careful consideration of the clinical background, distribution of disease, gross characteristics and spectrum of routine microscopic findings, will lead to the correct diagnosis in the majority of cases and at the very least lead to formulation of a considered differential diagnosis such that use of special techniques may be judicious and those results placed in context of the time-honored clinical and pathologic features.
  • [MeSH-major] Carcinoma / secondary. Krukenberg Tumor / secondary. Ovarian Neoplasms / secondary
  • [MeSH-minor] Diagnosis, Differential. Female. History, 19th Century. History, 20th Century. Humans

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  • (PMID = 17452813.001).
  • [ISSN] 1072-4109
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 67
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50. You J, Xu L, Zheng GY, Qiu JF: [Diagnosis, treatment, and prognosis of primary appendiceal tumors: analysis of 37 cases]. Zhonghua Yi Xue Za Zhi; 2008 Jul 15;88(27):1909-11

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis, treatment, and prognosis of primary appendiceal tumors: analysis of 37 cases].
  • OBJECTIVE: To investigate the pathology, diagnosis,treatment, and prognosis of primary appendiceal tumors.
  • METHODS: The clinical data of 37 patients with primary tumors of the appendix, 16 males and 21 females, aged 56 +/- 13 (35-87) hospitalized Jan.
  • All 37 cases received surgical operation with the diagnosis confirmed by pathology.
  • The pathological types included carcinoid tumor (n=12), mucinous tumor (n=17), and adenocarcinoma (n=8).
  • The 1, 3, and 5-year survival rates of the primary appendix carcinoid tumor, mucinous tumor, and adenocarcinoma were 100.0%, 100.0%, and 91.7%, 100.0%, 86.7%, and 71.5%, and 75.0%, 50.0%, and 50.0% respectively.
  • Intra-operative exploration and frozen section are very important for diagnosis and operation choice.
  • The prognosis of primary appendix carcinoid tumors is better.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Appendiceal Neoplasms / surgery

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  • (PMID = 19040005.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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51. Modlin IM, Kidd M, Latich I, Zikusoka MN, Eick GN, Mane SM, Camp RL: Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed. Ann Surg; 2006 Jul;244(1):52-60
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed.
  • OBJECTIVE: To use differential gene expression of candidate markers to discriminate benign appendiceal carcinoids (APCs) from malignant and mixed cell APCs.
  • SUMMARY BACKGROUND DATA: Controversy exists in regard to the appropriate surgical management of APCs since it is sometimes difficult to predict tumor behavior using traditional pathologic criteria.
  • We have identified 5 differentially expressed genes (a mitosis-regulatory gene NAP1L1, an adhesin MAGE-D2, an estrogen-antagonist, the metastasis marker MTA1, the apoptotic marker NALP, and chromogranin A) that define gut neuroendocrine cell behavior.
  • METHODS: Total RNA was isolated using TRIzol reagent from 42 appendiceal samples, including appendiceal carcinoids identified at exploration for appendicitis (no evidence of metastasis; n = 16), appendicitis specimens (n = 11), malignant appendiceal tumors (> 1.5 cm, evidence of metastatic invasion; n = 7), and mixed (goblet) cell appendiceal adenocarcinoids (n = 3), normal appendiceal tissue (n = 5), and 5 colorectal cancers.
  • RESULTS: CgA message was elevated (> 1000-fold, P < 0.05) in all tumor types.
  • NAP1L1 was elevated (> 10-fold, P < 0.03) in both malignant and goblet cell adenocarcinoids compared with normal and incidental lesions (P < 0.006).
  • MAGE-D2 and MTA1 message were significantly elevated (> 10-fold, P < 0.01) in the malignant and goblet cell adenocarcinoid tumors but not in the appendicitis-associated carcinoids or normal mucosa.
  • The apoptotic marker, NALP1, was overexpressed (> 50-fold, P < 0.05) in the appendicitis-associated and malignant appendiceal carcinoids but was significantly decreased (> 10-fold, P < 0.05) in the goblet cell adenocarcinoids.
  • Elevated CgA transcript and protein levels indicative of a carcinoid tumor were identified in one acute appendicitis sample with no histologic evidence of a tumor.
  • CONCLUSIONS: These data demonstrate that malignant APCs and goblet cell adenocarcinoids have elevated expression of NAP1L1, MAGE-D2, and MTA1 compared with appendiceal carcinoids identified at surgery for appendicitis.
  • This and the differences in NALP1 gene expression (decreased in goblet cell adenocarcinoids) provide a series of molecular signatures that differentiate carcinoids of the appendix.
  • The molecular delineation of malignant appendiceal tumor potential provides a scientific basis to define the appropriate surgical management as opposed to morphologic assessment alone.

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  • [Cites] Arch Intern Med. 1999 Sep 13;159(16):1841-5 [10493314.001]
  • [Cites] Am J Gastroenterol. 1998 Mar;93(3):422-8 [9517651.001]
  • [Cites] Cancer. 2005 Jan 15;103(2):229-36 [15599934.001]
  • [Cites] Gastroenterology. 2005 May;128(6):1717-51 [15887161.001]
  • [Cites] Ann Surg. 2006 Feb;243(2):273-80 [16432362.001]
  • [Cites] Ann Surg Oncol. 2006 Feb;13(2):253-62 [16424981.001]
  • [Cites] Cancer. 2006 Apr 1;106(7):1480-8 [16502410.001]
  • [Cites] Digestion. 2000;62 Suppl 1:33-8 [10940685.001]
  • [Cites] Am J Pathol. 2001 Feb;158(2):419-29 [11159180.001]
  • [Cites] J Clin Pathol. 2001 Apr;54(4):257-71 [11304841.001]
  • [Cites] Cancer. 2002 Mar 15;94(6):1821-9 [11920546.001]
  • [Cites] Mod Pathol. 2002 Jun;15(6):599-605 [12065772.001]
  • [Cites] Cancer. 2002 Jun 15;94(12):3307-12 [12115365.001]
  • [Cites] Am J Surg Pathol. 2002 Jul;26(7):863-72 [12131153.001]
  • [Cites] Nat Med. 2002 Nov;8(11):1323-7 [12389040.001]
  • [Cites] Pathol Oncol Res. 2002;8(3):204-19 [12516003.001]
  • [Cites] Cancer. 2003 Feb 15;97(4):934-59 [12569593.001]
  • [Cites] Exp Mol Pathol. 2003 Jun;74(3):336-40 [12782023.001]
  • [Cites] Eur J Surg Oncol. 2003 Oct;29(8):682-8 [14511618.001]
  • [Cites] Surg Oncol Clin N Am. 2003 Jul;12(3):585-603 [14567019.001]
  • [Cites] Br J Surg. 2003 Nov;90(11):1317-22 [14598408.001]
  • [Cites] Mod Pathol. 2003 Dec;16(12):1189-98 [14681318.001]
  • [Cites] Acta Oncol. 2003;42(7):672-92 [14690153.001]
  • [Cites] Biotechnol Bioeng. 2003 Dec 30;84(7):822-33 [14708123.001]
  • [Cites] Int J Oncol. 2004 Feb;24(2):305-12 [14719106.001]
  • [Cites] Dis Colon Rectum. 2004 Feb;47(2):163-9 [15043285.001]
  • [Cites] Int J Cancer. 2004 Jun 20;110(3):362-7 [15095300.001]
  • [Cites] Hum Pathol. 2004 Apr;35(4):424-9 [15116322.001]
  • [Cites] Am Surg. 2004 Jul;70(7):593-9 [15279181.001]
  • [Cites] Surg Endosc. 2004 Jul;18(7):1063-6 [15156378.001]
  • [Cites] Digestion. 1986;35 Suppl 1:3-22 [3539679.001]
  • [Cites] Acta Oncol. 1989;28(3):325-9 [2545231.001]
  • [Cites] N Engl J Med. 1992 Oct 29;327(18):1285-8 [1406819.001]
  • [Cites] Biochem J. 1994 Jan 15;297 ( Pt 2):389-97 [8297347.001]
  • [Cites] J Biol Chem. 1994 Sep 16;269(37):22958-63 [8083195.001]
  • [Cites] Gene. 1995 Jun 14;159(1):97-104 [7607577.001]
  • [Cites] Int J Cancer. 1997 Aug 22;74(4):459-63 [9291440.001]
  • [Cites] Dis Colon Rectum. 1998 Jan;41(1):75-80 [9510314.001]
  • [Cites] Appl Immunohistochem Mol Morphol. 2004 Sep;12(3):266-70 [15551742.001]
  • (PMID = 16794389.001).
  • [ISSN] 0003-4932
  • [Journal-full-title] Annals of surgery
  • [ISO-abbreviation] Ann. Surg.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA097050; United States / NCI NIH HHS / CA / R01-CA-097050
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Antigens, Neoplasm; 0 / Apoptosis Regulatory Proteins; 0 / Biomarkers, Tumor; 0 / Cell Cycle Proteins; 0 / Chromogranin A; 0 / Chromogranins; 0 / Genetic Markers; 0 / MAGED2 protein, human; 0 / NAP1L1 protein, human; 0 / NLRP1 protein, human; 0 / Nuclear Proteins; 0 / Nucleosome Assembly Protein 1; 0 / Repressor Proteins; EC 3.5.1.- / Mta1 protein, human; EC 3.5.1.98 / Histone Deacetylases
  • [Other-IDs] NLM/ PMC1570599
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52. Pan Z, Repertinger S, Leonard R, Bewtra C, Gatalica Z, Sharma P: Cervical and endometrial metastases of appendiceal goblet cell carcinoid. Arch Pathol Lab Med; 2010 May;134(5):776-80
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cervical and endometrial metastases of appendiceal goblet cell carcinoid.
  • Appendiceal goblet cell carcinoid (GCC) is a rare tumor with histologic features of both adenocarcinoma and neuroendocrine tumor (carcinoid).
  • Clinically, it behaves more aggressively than classic appendiceal carcinoid and commonly presents with peritoneal carcinomatosis.
  • The first patient's invasive cervical signet ring cell carcinoma was diagnosed on routine screening.
  • The second patient presented with abnormal uterine bleeding, and endometrial curettage showed an adenocarcinoma with signet ring cell features.
  • Metastatic appendiceal GCC to uterine cervix and endometrium can potentially be misinterpreted as primary cervical or endometrial signet ring cell carcinoma.
  • Therefore, for any uterine cervical/endometrial signet ring cell carcinoma, a metastatic appendiceal GCC should be considered in the differential diagnosis, especially after excluding other primary sites.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / secondary. Endometrial Neoplasms / secondary. Uterine Cervical Neoplasms / secondary

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  • (PMID = 20441511.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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53. Karavolos S, Caplin M, Benjamin E, Crow J, Mould T: Primary mucinous carcinoid tumour of the ovary: a case report. Eur J Gynaecol Oncol; 2006;27(6):618-20
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mucinous carcinoid tumour of the ovary: a case report.
  • Primary ovarian carcinoid tumours of the ovary are rare and represent less than 0.1% of ovarian malignancy.
  • We report a case of primary ovarian mucinous carcinoid tumour, of the atypical category, in a 34-year-old nulliparous woman.
  • This case adds to the body of evidence and demonstrates a possible good prognosis with non-aggressive behaviour in the atypical mucinous carcinoid group.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoid Tumor / surgery. Ovarian Neoplasms / surgery
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Leiomyoma / diagnosis. Prognosis. Treatment Outcome

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  • (PMID = 17290597.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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54. Yamada A, Yamamoto H, Arai O, Kiyosuke Y, Tsuji Y, Nakatsuji M, Fukatsu H, Miyoshi M, Kono H, Mouri H, Matsueda K, Tezen T, Shimamura J, Tsukayam C: [A case of goblet cell carcinoid of the appendix presented as a metastatic ovarian tumor and peritoneal dissemination, and diagnosed by autopsy]. Nihon Shokakibyo Gakkai Zasshi; 2005 Jul;102(7):905-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of goblet cell carcinoid of the appendix presented as a metastatic ovarian tumor and peritoneal dissemination, and diagnosed by autopsy].
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / secondary. Ovarian Neoplasms / secondary. Peritoneal Neoplasms / secondary

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  • (PMID = 16038438.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 12
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55. Arnold R, McCallion K, McGailie C: Goblet cell carcinoids of the appendix. Ulster Med J; 2006 Jan;75(1):40-5
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet cell carcinoids of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Carcinoid Tumor / diagnosis
  • [MeSH-minor] Abdominal Pain / etiology. Adult. Appendicitis / diagnosis. Appendicitis / surgery. Humans. Male. Nausea / etiology. Vomiting / etiology

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  • [Cites] Cancer. 2003 Feb 15;97(4):934-59 [12569593.001]
  • [Cites] Cancer. 2002 Jun 15;94(12):3307-12 [12115365.001]
  • [Cites] Ann Oncol. 2001;12 Suppl 2:S73-7 [11762356.001]
  • [Cites] Arch Pathol Lab Med. 2001 Mar;125(3):386-90 [11231488.001]
  • [Cites] Ann Oncol. 1997 Jul;8(7):685-90 [9296223.001]
  • [Cites] Br J Surg. 2003 Nov;90(11):1317-22 [14598408.001]
  • [Cites] Cancer. 1968 Feb;21(2):270-8 [4952505.001]
  • [Cites] Ann Surg. 1979 Jul;190(1):58-63 [464679.001]
  • [Cites] Cancer. 1974 Aug;34(2):338-44 [4852178.001]
  • [Cites] Ulster Med J. 2004 May;73(1):59-62 [15244130.001]
  • [Cites] Clin Nucl Med. 1997 Jul;22(7):467-9 [9227869.001]
  • (PMID = 16457403.001).
  • [ISSN] 0041-6193
  • [Journal-full-title] The Ulster medical journal
  • [ISO-abbreviation] Ulster Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Northern Ireland
  • [Number-of-references] 13
  • [Other-IDs] NLM/ PMC1891799
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56. Zhang XD, He CN, Zhai JP, Zhao HF, Chen C, Shi WD: [Goblet cell carcinoid of appendix: report of two cases]. Zhonghua Bing Li Xue Za Zhi; 2006 Feb;35(2):126-7
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Goblet cell carcinoid of appendix: report of two cases].
  • [MeSH-major] Appendiceal Neoplasms / pathology. Appendix / pathology. Carcinoid Tumor / pathology
  • [MeSH-minor] Adenocarcinoma, Mucinous / pathology. Aged. Appendectomy / methods. Appendicitis / pathology. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male

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  • (PMID = 16630495.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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57. Albores-Saavedra J, Henson DE, Batich K: Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix. Am J Surg Pathol; 2009 Aug;33(8):1259-60; author reply 1260-1
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix.
  • [MeSH-major] Adenocarcinoma / classification. Adenocarcinoma / pathology. Appendiceal Neoplasms / classification. Appendiceal Neoplasms / pathology. Carcinoid Tumor / classification. Carcinoid Tumor / pathology

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  • [CommentOn] Am J Surg Pathol. 2008 Oct;32(10):1429-43 [18685490.001]
  • (PMID = 19471156.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] United States
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58. Couvelard A: [Appendicular pathology. Goblet cell carcinoid]. Ann Pathol; 2010 Apr;30(2):120-3
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Appendicular pathology. Goblet cell carcinoid].
  • [Transliterated title] Pathologie de l'appendice. Cas no 6. Carcinoïde à cellules caliciformes (adénocarcinoïde).
  • [MeSH-major] Appendiceal Neoplasms / pathology. Appendicitis / etiology. Appendix / pathology. Carcinoid Tumor / pathology
  • [MeSH-minor] Alcian Blue. Appendectomy. Biomarkers, Tumor / analysis. Chromogranin A / analysis. Coloring Agents. Female. Humans. Keratin-20 / analysis. Middle Aged. Mucin-2 / analysis. Neoplasm Invasiveness. Neoplasm Proteins / analysis. Staining and Labeling

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  • (PMID = 20451070.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CHGA protein, human; 0 / Chromogranin A; 0 / Coloring Agents; 0 / Keratin-20; 0 / MUC2 protein, human; 0 / Mucin-2; 0 / Neoplasm Proteins; P4448TJR7J / Alcian Blue
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59. Chetty R: Goblet cell carcinoid tumours of the appendix: a unique neuroendocrine tumour. Histopathology; 2008 May;52(6):770-1
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Goblet cell carcinoid tumours of the appendix: a unique neuroendocrine tumour.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology
  • [MeSH-minor] Appendix / pathology. Humans

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  • [CommentOn] Histopathology. 2007 Dec;51(6):763-73 [18042066.001]
  • (PMID = 18439158.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
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60. Raja V, Balakrishnan R, Bollinger W, Crabtree D, Downey E, Mohindra M: Double diagnosis in cancer patients and cutaneous reaction related to gemcitabine: CASE 2. Mixed carcinoid-adenocarcinoma of the appendix. J Clin Oncol; 2005 Oct 1;23(28):7223-4
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Double diagnosis in cancer patients and cutaneous reaction related to gemcitabine: CASE 2. Mixed carcinoid-adenocarcinoma of the appendix.
  • [MeSH-major] Adenocarcinoma / pathology. Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 16192607.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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