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1. Farah-Klibi F, Kourda-Boujemaa J, Bouaskar I, Dziri C, Rachida Z, Jilani-Baltagi SB: Cystadenocarcinoma of the appendix: an incidental perioperatory finding in a patient with adenocarcinoma of the ascending and sigmoid colon: case report and review of literature. Pathologica; 2009 Dec;101(6):255-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystadenocarcinoma of the appendix: an incidental perioperatory finding in a patient with adenocarcinoma of the ascending and sigmoid colon: case report and review of literature.
  • BACKGROUND: Primary adenocarcinomas of the appendix are uncommon, constituting 1% of all colorectal malignancies.
  • Appendiceal malignancies often present atypically, thus creating diagnostic challenges.
  • Although there are many pathology reports of primary cystadenocarcinoma of the appendix, only a limited number of cases have appeared in the radiological or surgical literature.
  • We present a unique case of primary cystadenocarcinoma of the appendix occurring concurrently with adenocarcinoma of the colon, and overview the clinical and therapeutic difficulties posed by this rare entity.
  • CASE PRESENTATION: A mucocele of the appendix, due to mucinous cystadenocarcinoma, was documented as an incidental perioperatory finding in a 68-year-old female.
  • At laparoscopy, a cystic appendiceal lesion was found, without perforation.
  • CONCLUSIONS: Preoperative diagnosis of an underlying malignancy in a mucocele is important for patient management, but is difficult to reach by imaging studies alone.
  • Synchronous colon cancer may occur in patients with appendiceal mucoceles.
  • [MeSH-major] Adenocarcinoma / pathology. Appendiceal Neoplasms / pathology. Colonic Neoplasms / pathology. Cystadenocarcinoma / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 20387715.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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2. Fornaro R, Picori E, Stabilini C, Frascio M, Sticchi C, Boccardo C, Ricci B, Giannetta E: [Carcinoid tumors of the appendix: when right colectomy?]. G Chir; 2006 May;27(5):233-9
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  • [Title] [Carcinoid tumors of the appendix: when right colectomy?].
  • [Transliterated title] I tumori carcinoidi dell'appendice. Quando l'emicolectomia destra?
  • Three cases of carcinoid tumour of the appendix (about 0,3 % of all performed appendectomies) has induced the Authors to a review of the literature with the aim to underline the most important biological and pathological findings and the current clinic and therapeutic knowledges.
  • The diagnosis before surgery is rarely made; it is formulated incidentally in most patients by the histological exam during the operation for an appendicitis or during other surgical procedures.
  • The kind of surgical intervention, that is the entity of the surgical demolition, for the treatment of the carcinoid tumours of the appendix is still controversial: appendectomy or right colectomy?
  • It is possible identify, also during the operation for an appendicitis or for other abdominal lesions, criteria that can orient toward a major surgery (size of the neoplasia, subserosal lymphatic invasion, infiltration of the serosa, diffusion in the meso-appendix, location in closeness of the base of the appendix, invasion of the the locoregional lymph nodes, presence of metastases, section ?margins, number of mitoses, cellular pleiomorfism).
  • [MeSH-major] Appendectomy. Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery. Colectomy

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  • (PMID = 16857114.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 31
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3. Tan KB, Tan LH, Soo R, Putti TC, Chong SM: Involvement of the appendix and palate by pleomorphic variant mantle cell lymphoma. Leuk Lymphoma; 2006 Aug;47(8):1704-7
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  • [Title] Involvement of the appendix and palate by pleomorphic variant mantle cell lymphoma.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Jaw Neoplasms / diagnosis. Lymphoma, Mantle-Cell / diagnosis. Lymphoma, Non-Hodgkin / diagnosis

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  • (PMID = 16966294.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Interferon Regulatory Factors; 0 / Ki-67 Antigen; 0 / interferon regulatory factor-4
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4. Rout S, Renehan AG, Parkinson MF, Saunders MP, Fulford PE, Wilson MS, O'Dwyer ST: Treatments and outcomes of peritoneal surface tumors through a centralized national service (United kingdom). Dis Colon Rectum; 2009 Oct;52(10):1705-14
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  • [Title] Treatments and outcomes of peritoneal surface tumors through a centralized national service (United kingdom).
  • METHODS: A prospective database of patients referred to the Manchester Peritoneal Tumor Service, established in 2002, was analyzed.
  • Among the 118 surgically treated, the most common diagnosis was pseudomyxoma peritonei (101 patients, 86%).
  • Where complete cytoreduction was achieved, three-year and five-year tumor-related survival rates were 94% and 86%, respectively.
  • In the Cox model, incompleteness of cytoreduction (P = 0.001) and high-grade tumor (P < 0.0001) were independent prognosticators of poor outcome.
  • Having achieved low levels of morbidity and mortality in the treatment of mainly pseudomyxoma peritonei of appendiceal origin, the technique of cytoreductive surgery and heated intraperitoneal chemotherapy may be considered for peritoneal carcinomatosis of colorectal origin.
  • [MeSH-major] Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / surgery. Pseudomyxoma Peritonei / drug therapy. Pseudomyxoma Peritonei / surgery

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  • [CommentIn] Dis Colon Rectum. 2010 Aug;53(8):1218-9; author reply 1219-20 [20628288.001]
  • [CommentIn] Dis Colon Rectum. 2009 Oct;52(10):1714-5 [19966602.001]
  • (PMID = 19966601.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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5. To AC, Looi KL, Damianovich D, Taylor GB, Sidebotham D, White HD: A case of cardiogenic shock caused by capecitabine treatment. Nat Clin Pract Cardiovasc Med; 2008 Nov;5(11):725-9
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  • BACKGROUND: A 52-year-old woman underwent successful resection of stage IIB primary mucinous adenocarcinoma of the appendix and was started on capecitabine chemotherapy.
  • DIAGNOSIS: Capecitabine-induced cardiogenic shock.
  • [MeSH-major] Adenocarcinoma, Mucinous / drug therapy. Antimetabolites, Antineoplastic / adverse effects. Appendiceal Neoplasms / drug therapy. Deoxycytidine / analogs & derivatives. Fluorouracil / analogs & derivatives. Shock, Cardiogenic / chemically induced

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  • (PMID = 18813211.001).
  • [ISSN] 1743-4300
  • [Journal-full-title] Nature clinical practice. Cardiovascular medicine
  • [ISO-abbreviation] Nat Clin Pract Cardiovasc Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Biomarkers; 0 / Cardiotonic Agents; 0W860991D6 / Deoxycytidine; 6804DJ8Z9U / Capecitabine; U3P01618RT / Fluorouracil
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6. Deschamps L, Couvelard A: Endocrine tumors of the appendix: a pathologic review. Arch Pathol Lab Med; 2010 Jun;134(6):871-5
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  • [Title] Endocrine tumors of the appendix: a pathologic review.
  • CONTEXT: Although rare, appendiceal endocrine tumors are the most common neoplasms of the appendix.
  • OBJECTIVE: To provide recent data that focus on the pathology of endocrine tumors of the appendix including classifications and guidelines for patient management.
  • CONCLUSIONS: Appendiceal endocrine tumors are separated into 2 main groups: classic endocrine tumors and goblet cell carcinoids.
  • Evaluation of their prognoses and risks of malignancy, according to these classifications, depends on several parameters including tumor size, proliferation rate, and infiltration of appendiceal wall and mesoappendix.
  • Most patients with classic endocrine tumors of the appendix have a favorable prognosis.
  • Indications for postappendectomy, complementary surgery, which are still controversial, especially for tumors between 1 and 2 cm, are presented and discussed.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoma, Neuroendocrine / pathology
  • [MeSH-minor] Appendectomy. Carcinoid Tumor / classification. Carcinoid Tumor / diagnosis. Carcinoid Tumor / pathology. Colectomy. Humans. Prognosis. World Health Organization

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  • (PMID = 20524865.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 41
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7. Savchenko IuP, Polovinkin VV, Fedosov SR, Pryn' PS: [Combination of giant mucocele of the appendix and adenocarcinoma of the rectum]. Khirurgiia (Mosk); 2006;(10):57-9
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  • [Title] [Combination of giant mucocele of the appendix and adenocarcinoma of the rectum].
  • [MeSH-major] Adenocarcinoma / complications. Appendiceal Neoplasms / complications. Mucocele / complications. Rectal Neoplasms / complications
  • [MeSH-minor] Aged. Appendectomy. Biopsy. Colectomy. Diagnosis, Differential. Female. Humans. Severity of Illness Index. Tomography, X-Ray Computed

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  • (PMID = 17167911.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Russia (Federation)
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8. Louzi A, Nargis Y, Belaabidia B, Alatawna H, Benelkhaiat R, Finech B, Dafali AE: [Appendicular mucocele caused by carcinoid tumor during pregnancy]. Gynecol Obstet Fertil; 2006 Nov;34(11):1051-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Appendicular mucocele caused by carcinoid tumor during pregnancy].
  • [Transliterated title] Mucocèle de l'appendice sur tumeur carcinoïde pendant la grossesse.
  • Mucocele of the appendix secondary to appendicular carcinoid tumour is a rare entity.
  • The interaction between carcinoid tumour or mucocele of the appendix and pregnancy is not yet elucidated.
  • Prognosis depends on the size of the carcinoid tumour and its regional invasion.
  • We report a case of appendicular mucocele caused by a carcinoid tumour in a 36-year-old pregnant woman who had been admitted because of acute appendicitis.
  • Pathological examination of the appendicectomy specimen revealed a carcinoid tumour measuring 2 cm.
  • According to this case and depending on the literature, the authors discuss the diagnosis and the therapeutic modalities proposed for this rare entity.
  • [MeSH-major] Appendiceal Neoplasms / complications. Carcinoid Tumor / complications. Mucocele / etiology. Pregnancy Complications, Neoplastic / surgery


9. Sugarbaker PH: Strategies for the prevention and treatment of peritoneal carcinomatosis from gastrointestinal cancer. Cancer Invest; 2005;23(2):155-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: In a series of phase II studies, appendiceal tumors with peritoneal seeding became the paradigm for success with an 85% long-term survival in selected patients.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma / drug therapy. Carcinoma / prevention & control. Colonic Neoplasms / pathology. Gastrointestinal Neoplasms / pathology. Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / prevention & control
  • [MeSH-minor] Humans. Infusions, Parenteral. Intraoperative Period. Neoplasm Invasiveness. Neoplastic Cells, Circulating. Patient Selection. Prognosis

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  • (PMID = 15813509.001).
  • [ISSN] 0735-7907
  • [Journal-full-title] Cancer investigation
  • [ISO-abbreviation] Cancer Invest.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 37
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10. Guo AT, Wei LX, Song X: [Histologic classification and prognostic implication of pseudomyxoma peritonei]. Zhonghua Bing Li Xue Za Zhi; 2007 Jul;36(7):474-9
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  • The mean age of the patients at the time of diagnosis was 50.3 years (age range = 22 to 76 years).
  • On the other hand, the presence of appendiceal tumor, parenchymal invasion of abdominal viscera, cellularity, architecture, nuclear atypia and mitotic activity of the peritoneal lesion significantly correlated with survival.
  • The prognosis was even worse in the presence of appendiceal carcinoma or parenchymal invasion of abdominal viscera.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Adenoma / pathology. Appendiceal Neoplasms / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology
  • [MeSH-minor] Adult. Aged. Appendectomy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness. Retrospective Studies. Survival Rate. Young Adult

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  • (PMID = 17845762.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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11. Iwańczak B, Stawarski A, Czernik J, Bronowickip K, Iwańczak F, Pytrus T, Klempous J, Godziński J: [Diagnostic difficulties in pediatric abdominal pain with potential appendicitis]. Przegl Lek; 2007;64 Suppl 3:56-60
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  • [Transliterated title] Trudności diagnostyczne przyczyn bólów brzucha okolicy wyrostka robaczkowego u dzieci.
  • RESULTS: The most often Crohn's disease were recognized (9 children), in 2 cases with concomitant other pathologies (fecal tumor of appendix in one case and with peritoneal abscess after perforation of intestinal wall).
  • In one boy with ulcerative colitis, during exacerbation of the disease appendicitis complicated by rupture and peritonitis was observed.
  • Carcinoid of the appendix was the cause of abdominal pain in one child.
  • 3. All children with periappendipected of Crohn's disease.
  • 4. All children with equivocal presentations of appendicitis and with normal appendix during operation should undergo further diagnostic evaluation.
  • [MeSH-major] Abdominal Pain / etiology. Appendicitis / diagnosis
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Infant. Male

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  • (PMID = 18431916.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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12. O'Kane AM, O'Donnell ME, Shah R, Carey DP, Lee J: Small cell carcinoma of the appendix. World J Surg Oncol; 2008;6:4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Small cell carcinoma of the appendix.
  • Computerised tomography revealed an appendiceal lesion and multiple liver metastases.
  • Exploratory laparotomy and right hemicolectomy was performed with histopathological analysis confirming a primary small cell carcinoma of her appendix.
  • CONCLUSION: This is the first reported case of a pure extrapulmonary carcinoma arising from the appendix.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoma, Small Cell / secondary. Liver Neoplasms / secondary
  • [MeSH-minor] Appendectomy / methods. Colectomy / methods. Colonoscopy. Diagnosis, Differential. Fatal Outcome. Female. Follow-Up Studies. Humans. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18197972.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2241597
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13. Coursey CA, Nelson RC, Moreno RD, Dodd LG, Patel MB, Vaslef S: Carcinoid tumors of the appendix: are these tumors identifiable prospectively on preoperative CT? Am Surg; 2010 Mar;76(3):273-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoid tumors of the appendix: are these tumors identifiable prospectively on preoperative CT?
  • The purpose of this study was to determine if carcinoid tumors of the appendix were identified prospectively on preoperative CT at our institution during the last decade.
  • A surgical database search performed using the Current Procedural Terminology codes for appendectomy and colectomy yielded 2108 patients who underwent appendectomy or colectomy with removal of the appendix from January 1998 through September 2007.
  • Pathology reports were reviewed to identify patients in whom an appendiceal carcinoid tumor was identified.
  • Twenty-three carcinoid tumors (1.1%; 15 women [65.2%], eight men [34.8%]; average age 54 years [range, 23 to 86 years]) were identified.
  • No tumors were identified prospectively on CT.
  • Average reported tumor size was 6.1 mm (range, 1.5 to 15 mm; n = 18).
  • A tip or distal location was reported for all tumors for which a location was given (n = 15).
  • Carcinoid tumors occurred in 1.1 per cent of appendix specimens.
  • These tumors were all less than or 1.5 cm in size.
  • Likely as a result of their small size, none of these tumors was identified prospectively on preoperative CT.
  • [MeSH-major] Appendiceal Neoplasms / radiography. Carcinoid Tumor / radiography. Tomography, X-Ray Computed
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / surgery. Adult. Aged. Aged, 80 and over. Female. Humans. Incidental Findings. Intestinal Neoplasms / epidemiology. Intestinal Neoplasms / surgery. Male. Middle Aged. Neoplasms, Multiple Primary / surgery. Preoperative Period. Young Adult

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  • (PMID = 20349655.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Klöppel G, Anlauf M: Epidemiology, tumour biology and histopathological classification of neuroendocrine tumours of the gastrointestinal tract. Best Pract Res Clin Gastroenterol; 2005 Aug;19(4):507-17
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiology, tumour biology and histopathological classification of neuroendocrine tumours of the gastrointestinal tract.
  • The term 'carcinoid', although well established in medical terminology, is therefore no longer adequate to cover the entire spectrum of neuroendocrine neoplasms.
  • [MeSH-major] Carcinoma, Neuroendocrine / pathology. Gastrointestinal Neoplasms / pathology
  • [MeSH-minor] Appendiceal Neoplasms / pathology. Cell Differentiation. Colonic Neoplasms / pathology. Esophageal Neoplasms / pathology. Humans. Ileal Neoplasms / pathology. Jejunal Neoplasms / pathology. Multiple Endocrine Neoplasia Type 1 / epidemiology. Multiple Endocrine Neoplasia Type 1 / pathology. Neoplasm Invasiveness. Prognosis. Rectal Neoplasms / pathology. Somatostatinoma / pathology. Stomach Neoplasms / pathology

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  • (PMID = 16183524.001).
  • [ISSN] 1521-6918
  • [Journal-full-title] Best practice & research. Clinical gastroenterology
  • [ISO-abbreviation] Best Pract Res Clin Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 43
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15. Delfosse V, Dome F, Detrembleur N, Wetz P, Boniver J, Fridman V: [Neuroendocrine tumors of the appendix]. Rev Med Liege; 2009 Jul-Aug;64(7-8):361-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Neuroendocrine tumors of the appendix].
  • [Transliterated title] Tumeurs neuroendocrines appendiculaires: à propos d'un cas, de l'histologie à la thérapeutique.
  • The histological study of the appendix revealed a tubular variant of endocrine carcinoma of the appendix.
  • Neuroendocrine tumors ("NETs") of the appendix are rare tumors which are usually detected incidentally, affecting 0.3% to 0.9% of appendectomies.
  • Depending on their size, but also on some other factors, including histologic type, these tumors will require specific treatment; sometimes appendectomy will not be sufficient.
  • [MeSH-major] Appendectomy. Appendiceal Neoplasms / pathology. Appendiceal Neoplasms / surgery. Carcinoma, Neuroendocrine / pathology. Carcinoma, Neuroendocrine / surgery
  • [MeSH-minor] Appendicitis / etiology. Appendicitis / pathology. Appendicitis / surgery. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Neuroendocrine Tumors / pathology. Neuroendocrine Tumors / surgery. Prognosis. Treatment Outcome. Young Adult

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  • (PMID = 19777911.001).
  • [ISSN] 0370-629X
  • [Journal-full-title] Revue médicale de Liège
  • [ISO-abbreviation] Rev Med Liege
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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16. Morris DL: Re: An evidence-based approach: Sugarbaker protocol and pseudomyxoma peritonei of appendiceal origin. ANZ J Surg; 2008 Nov;78(11):1043; author reply 1043
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  • [Title] Re: An evidence-based approach: Sugarbaker protocol and pseudomyxoma peritonei of appendiceal origin.
  • [MeSH-major] Appendiceal Neoplasms / complications. Clinical Protocols. Pseudomyxoma Peritonei / surgery

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  • [CommentOn] ANZ J Surg. 2008 May;78(5):327-8 [18380718.001]
  • (PMID = 18959716.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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17. Chetty R: Goblet cell carcinoid tumours of the appendix: a unique neuroendocrine tumour. Histopathology; 2008 May;52(6):770-1
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  • [Title] Goblet cell carcinoid tumours of the appendix: a unique neuroendocrine tumour.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology
  • [MeSH-minor] Appendix / pathology. Humans

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  • [CommentOn] Histopathology. 2007 Dec;51(6):763-73 [18042066.001]
  • (PMID = 18439158.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
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18. Lai HW, Loong CC, Chiu JH, Chau GY, Wu CW, Lui WY: Interval appendectomy after conservative treatment of an appendiceal mass. World J Surg; 2006 Mar;30(3):352-7
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  • [Title] Interval appendectomy after conservative treatment of an appendiceal mass.
  • INTRODUCTION: The purpose of this study was to clarify the role of interval appendectomy after conservative treatment of an appendiceal mass.
  • METHODS: From January 1998 to December 2003, patients with an appendiceal mass who received conservative treatment at the Taipei Veterans General Hospital were studied retrospectively.
  • Of the 165 patients, 17 (10.3%) had their diagnosis changed after survey or surgery, and 5 (3.03%) were found to have colon cancer upon follow-up.
  • CONCLUSIONS: Patients who recovered from conservative treatment of an appendiceal mass should undergo colonoscopy or barium enema to detect any underlying diseases and to rule out coexistent colorectal cancer.
  • [MeSH-major] Appendectomy / methods. Appendiceal Neoplasms / surgery. Appendiceal Neoplasms / therapy. Appendicitis / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Barium Sulfate. Chi-Square Distribution. Child. Colonoscopy. Colorectal Neoplasms / diagnosis. Contrast Media. Diagnosis, Differential. Enema. Female. Humans. Male. Middle Aged. Postoperative Complications. Recurrence. Retrospective Studies. Treatment Outcome

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  • (PMID = 16479354.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 25BB7EKE2E / Barium Sulfate
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19. Yan TD, Chu F, Links M, Kam PC, Glenn D, Morris DL: Cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis from colorectal carcinoma: non-mucinous tumour associated with an improved survival. Eur J Surg Oncol; 2006 Dec;32(10):1119-24
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  • [Title] Cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis from colorectal carcinoma: non-mucinous tumour associated with an improved survival.
  • All appendiceal cancers were excluded.
  • Patients with mucinous tumour had relatively more extensive intraperitoneal disease.
  • [MeSH-major] Adenocarcinoma / secondary. Adenocarcinoma / therapy. Colorectal Neoplasms / pathology. Peritoneal Neoplasms / secondary. Peritoneal Neoplasms / therapy

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  • (PMID = 16887321.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 50SG953SK6 / Mitomycin
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20. Vang R, Gown AM, Barry TS, Wheeler DT, Yemelyanova A, Seidman JD, Ronnett BM: Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases. Am J Surg Pathol; 2006 Sep;30(9):1130-9
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  • [Title] Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases.
  • Coordinate expression profiles for cytokeratins 7 and 20 (CK7 and CK20) are useful for distinguishing certain types of adenocarcinomas but use for distinction of primary and secondary mucinous tumors in the ovary is limited due to the existence of a number of tumor types exhibiting overlapping CK7/CK20 immunoprofiles; the use of staining distribution patterns in the distinction of tumors with shared profiles has not been evaluated in detail.
  • We report analysis of both coordinate expression profiles and staining distribution in 179 rigorously classified mucinous tumors in the ovary, including 53 primary tumors [35 atypical proliferative (borderline) mucinous tumors of gastrointestinal type and 18 invasive mucinous carcinomas] and 126 secondary tumors [28 colorectal adenocarcinomas, 54 appendiceal tumors (23 adenocarcinomas, 31 low-grade adenomatous mucinous tumors associated with pseudomyxoma peritonei), 14 pancreatic adenocarcinomas, 8 endocervical adenocarcinomas, 5 gastric adenocarcinomas, 4 gallbladder/biliary tract adenocarcinomas, and 13 adenocarcinomas of unknown primary sites).
  • A CK7+/CK20+ immunoprofile was the most common profile in primary ovarian tumors (74%), upper gastrointestinal tract tumors (78%), and endocervical tumors (88%) but was occasionally observed in lower intestinal tract tumors (colorectal: 11%; appendiceal: 13% of low-grade tumors, 35% of carcinomas).
  • A CK7-/CK20+ immunoprofile was the most common profile in lower intestinal tract tumors (79%) and was uncommon in upper gastrointestinal tract tumors (9%), rarely seen in primary ovarian tumors (4%), and not seen in endocervical tumors.
  • A CK7+/CK20- profile was observed in some primary ovarian (23%), upper gastrointestinal tract (13%), and endocervical tumors (13%) but not in lower intestinal tract tumors.
  • For CK7+ tumors, staining distribution was very frequently diffuse (>50% of tumors cells positive) in primary ovarian, upper gastrointestinal tract, and endocervical tumors, whereas staining distribution was often focal (<50% of tumors cells positive) when present in colorectal and appendiceal carcinomas but not in low-grade appendiceal tumors.
  • For CK20+ tumors, staining distribution was variable but often focal in primary ovarian tumors and nonlower intestinal tract tumors, whereas the pattern was almost always diffuse in lower intestinal tract tumors.
  • Immunohistochemical staining distribution can supplement CK7/CK20 coordinate expression profiles to distinguish subsets of primary ovarian and metastatic lower intestinal tract mucinous tumors having overlapping immunoprofiles but neither coordinate expression profiles nor staining distribution distinguishes primary ovarian tumors from the nonlower intestinal tract metastases.
  • [MeSH-major] Adenocarcinoma, Mucinous / chemistry. Keratins / analysis. Ovarian Neoplasms / chemistry
  • [MeSH-minor] Adenocarcinoma / chemistry. Coloring Agents. Female. Gastrointestinal Neoplasms / chemistry. Humans. Immunohistochemistry. Keratin-20. Keratin-7. Pseudomyxoma Peritonei / complications. Uterine Cervical Neoplasms / chemistry

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  • (PMID = 16931958.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 68238-35-7 / Keratins
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21. Lepistö A, Osterlund P, Järvinen HJ: [Treatment of pseudomyxoma peritonei is developing]. Duodecim; 2010;126(14):1693-9
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  • In pseudomyxoma peritonei a mucinous tumor of the appendix spreads into the abdominal cavity.
  • Cytologic picture of the tumor may be benign, malignant or intermediary.
  • The symptoms were previously relieved by repeated resections of the tumor mass, whereby even the most benign form of the disease progressed slowly.
  • [MeSH-major] Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / surgery. Pseudomyxoma Peritonei / drug therapy. Pseudomyxoma Peritonei / surgery
  • [MeSH-minor] Antineoplastic Agents / administration & dosage. Appendix / pathology. Combined Modality Therapy. Disease Progression. Humans. Neoplasm Invasiveness. Therapeutic Irrigation / methods

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  • (PMID = 20804088.001).
  • [ISSN] 0012-7183
  • [Journal-full-title] Duodecim; lääketieteellinen aikakauskirja
  • [ISO-abbreviation] Duodecim
  • [Language] fin
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Finland
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 22
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22. Miyazaki T, Ishiguro T, Ishibashi K, Itoyama S, Ishida H: Mucosa-associated lymphoid tissue lymphoma of the appendix vermiformis. Int Surg; 2010 Jan-Mar;95(1):27-32
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  • [Title] Mucosa-associated lymphoid tissue lymphoma of the appendix vermiformis.
  • Computed tomography demonstrated right hydronephrosis and an irregular mass of 4 x 3 cm adjacent to the ileocecal region and iliopsoas muscle.
  • Laparotomy showed an appendiceal tumor invading the cecum, mesocolon, right ureter, and duodenum.
  • This is the sixth documented case of primary MALT lymphoma of the appendix.
  • The spectrum of sites in which gastrointestinal MALT lymphomas occur should be expanded to include the appendix.
  • [MeSH-major] Appendiceal Neoplasms / surgery. Lymphoma, B-Cell, Marginal Zone / surgery
  • [MeSH-minor] Antibodies, Monoclonal / blood. Antibodies, Monoclonal, Murine-Derived. Antigens, CD79 / blood. Female. Humans. Immunohistochemistry. Middle Aged. Neoplasm Invasiveness. Rituximab. Tomography, X-Ray Computed

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  • (PMID = 20480837.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, CD79; 4F4X42SYQ6 / Rituximab
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23. Gidwani AL, Blake G: Four pathologies in one. Ir J Med Sci; 2008 Mar;177(1):77-8
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  • Incidental findings as Meckel's diverticulum or Crohn's disease during this operation are not uncommon.
  • METHODS: Laparotomy revealed a perforated appendix with an incidental Meckel's diverticulum and thickened distal small bowel with fat encroaching the mesentery suggestive of active Crohn's disease.
  • A routine appendicectomy was done and pathology revealed inflamed perforated appendix with an incidental carcinoid within the appendix.
  • CONCLUSIONS: Presence of active Crohn's disease along with an incidental Meckel's diverticulum or acute appendicitis raises controversies in their surgical management.
  • [MeSH-major] Appendiceal Neoplasms / complications. Appendicitis / complications. Carcinoid Tumor / complications. Colitis, Ulcerative / complications. Meckel Diverticulum / complications

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  • (PMID = 17628741.001).
  • [ISSN] 1863-4362
  • [Journal-full-title] Irish journal of medical science
  • [ISO-abbreviation] Ir J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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24. Mang T, Maier A, Plank C, Mueller-Mang C, Herold C, Schima W: Pitfalls in multi-detector row CT colonography: a systematic approach. Radiographics; 2007 Mar-Apr;27(2):431-54
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  • Knowledge of the morphologic and attenuation characteristics of common colonic lesions and artifacts can help identify bulbous haustral folds, impacted diverticula, an inverted appendiceal stump, or mobile polyps, any of which may pose problems for the radiologist.
  • A combined two-dimensional and three-dimensional imaging approach is recommended for each colonic finding.
  • [MeSH-major] Artifacts. Colonic Neoplasms / radiography. Colonography, Computed Tomographic / instrumentation. Colonography, Computed Tomographic / methods. Polyps / radiography. Radiographic Image Enhancement / methods
  • [MeSH-minor] Diagnosis, Differential. Humans. Practice Guidelines as Topic

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  • [Copyright] (c) RSNA, 2007.
  • (PMID = 17374862.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 72
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25. Iwuagwu OC, Jameel JK, Drew PJ, Hartley JE, Monson JR: Primary carcinoma of the appendix - Hull series. Dig Surg; 2005;22(3):163-7
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  • [Title] Primary carcinoma of the appendix - Hull series.
  • BACKGROUND: Appendiceal carcinoma (AC) is a rare entity that does not have a well-defined treatment strategy.
  • At presentation, most patients are clinically thought to have appendicitis and the diagnosis is made only by formal histology.
  • Once the diagnosis of AC is made, patients are treated by various strategies including surgery, chemotherapy depending on nodal status of the disease.
  • The histopathology reports of all appendiceal specimens removed were traced.
  • Five patients survived at least 4 years from the time of diagnosis.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Appendiceal Neoplasms / surgery

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  • [Copyright] Copyright (c) 2005 S. Karger AG, Basel.
  • (PMID = 16037676.001).
  • [ISSN] 0253-4886
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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26. Hosaka A, Masaki Y, Yamasaki K, Aoki F, Sugizaki K: Pseudomyxoma peritonei presenting with femoral hernias and peritonitis. J Gastrointest Surg; 2007 Nov;11(11):1576-8
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  • Pseudomyxoma peritonei is a rare disease characterized by intraperitoneal accumulation of mucinous ascites produced by neoplastic cells, which mostly originate from an appendiceal adenoma.
  • The clinical presentation of the disease varies, and preoperative diagnosis is often difficult.
  • Laparotomy was performed, during which we found extensive diffuse gelatinous material mixed with purulent ascites, and the diagnosis of pseudomyxoma peritonei was confirmed.
  • The disease is rarely associated with femoral hernias or peritonitis.
  • [MeSH-major] Hernia, Inguinal / etiology. Peritonitis / etiology. Pseudomyxoma Peritonei / diagnosis
  • [MeSH-minor] Aged. Female. Humans. Peritoneal Neoplasms / diagnostic imaging. Peritoneal Neoplasms / surgery. Tomography, X-Ray Computed

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  • (PMID = 17508254.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Abdalla MF, El-Hennawy HM: Unusual presentation for primary appendiceal lymphoma: A case report. Indian J Surg; 2010 Jul;72(Suppl 1):289-92
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  • [Title] Unusual presentation for primary appendiceal lymphoma: A case report.
  • Primary appendiceal neoplasms are uncommon, being found in approximately 0.5%-1.0% of appendectomy specimens at pathologic evaluation.
  • Primary appendiceal Burkitt's lymphomas are rare occurring in 0.015% of all gastrointestinal lymphomas.
  • Almost all reported cases of appendiceal lymphoma have proved to be non-Hodgkin lymphoma.
  • The majority of appendiceal lymphomas are of B-cell.
  • This report describes a rare case of primary appendiceal lymphoma in a patient presented with hematuria and dull aching right lower abdominal and back pain.

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  • (PMID = 23133274.001).
  • [ISSN] 0972-2068
  • [Journal-full-title] The Indian journal of surgery
  • [ISO-abbreviation] Indian J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3451848
  • [Keywords] NOTNLM ; Appendix / Burkitt’s / Lymphoma
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28. Mattavelli F, Collini P, Pizzi N, Gervasoni C, Pennacchioli E, Mazzaferro V, Thyroid Cancer Study Group of INT Milan: Thyroid as a target of metastases. A case of foregut neuroendocrine carcinoma with multiple abdominal metastases and a thyroid localization after 21 years. Tumori; 2008 Jan-Feb;94(1):110-3
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  • In case of thyroid metastases, the site of the primary tumor is most often the breast, lung or kidney.
  • A thyroid metastasis from a foregut neuroendocrine tumor is very unusual and requires a differential diagnosis with primary neuroendocrine tumor of the gland itself, i.e., a medullary thyroid carcinoma.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoma, Neuroendocrine / secondary. Liver Neoplasms / secondary. Neoplasms, Multiple Primary / pathology. Thyroid Neoplasms / secondary
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Lymphatic Metastasis. Neoplasm Recurrence, Local / etiology

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  • (PMID = 18468344.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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29. Lee CT, Lien WC, Wang HP, Lin BR, Huang PH, Lin JT: Primary appendiceal adenocarcinoma with cecocolic intussusception. J Gastroenterol Hepatol; 2006 Jun;21(6):1079-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary appendiceal adenocarcinoma with cecocolic intussusception.
  • [MeSH-major] Adenocarcinoma / complications. Appendiceal Neoplasms / complications. Cecal Diseases / diagnosis. Intussusception / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 16725004.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Australia
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30. Harada K, Sakai I, Muramaki M, Kurahashi T, Yamanaka K, Hara I, Inoue TA, Miyake H: Reconstruction of urinary tract combined with surgical management of locally advanced non-urological cancer involving the genitourinary organs. Urol Int; 2006;76(1):82-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: This study included a total of 37 patients undergoing some type of urinary reconstruction due to invasion of the urological organs by locally advanced pelvic cancers, including 17 rectal cancers, 9 cervical cancers, 4 sigmoid cancers, 4 retroperitoneal sarcomas, 2 ovarian cancers and 1 appendiceal cancer.
  • Among these 37, 18 were recurrent cancers following initial surgery for primary tumors.
  • [MeSH-major] Pelvic Neoplasms / surgery. Urologic Surgical Procedures / methods

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  • [Copyright] Copyright (c) 2006 S. Karger AG, Basel.
  • (PMID = 16401927.001).
  • [ISSN] 0042-1138
  • [Journal-full-title] Urologia internationalis
  • [ISO-abbreviation] Urol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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31. Ayhan A, Gultekin M, Sağlam EA, Dursun P, Dogan NU, Aksan G, Usubutun A, Yuce K: Depth of invasion for appendiceal metastasis of ovarian cancers: does it have any clinical significance? J Obstet Gynaecol Res; 2008 Aug;34(4):557-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Depth of invasion for appendiceal metastasis of ovarian cancers: does it have any clinical significance?
  • AIM: Depth of appendiceal metastasis in patients with epithelial ovarian carcinoma (EOC) has not been previously analyzed for a possible relationship with clinico-pathological variables.
  • All of the patients had appendiceal metastasis.
  • Appendiceal metastases were defined as serosal (if tumoral spread involved only serosa of the appendix) or sero-mucosal (if tumoral spread also involved either muscular or mucosal surfaces of the appendix).
  • RESULTS: Thirty-nine patients had serosal appendiceal metastasis (56.5%), while the remaining 30 patients (43.5%) had appendiceal metastasis extending toward the muscular layer (seromucosal metastasis: 16 within muscularis mucosa, 14 within the mucosa of the appendix).
  • The mean age at the time of diagnosis was 54.58 years (range, 26-88 years), with no significant difference between the groups (P = 0.9).
  • This figure was 25% for patients with only muscular metastasis and 41.6% for patients with appendiceal metastasis extending to the mucosal layer (P = 0.2).
  • CONCLUSION: This is the first report to analyze the metastatic pattern of EOC on the appendix with respect to depth of invasion which could not reveal a significant difference.
  • [MeSH-major] Appendiceal Neoplasms / secondary. Ovarian Neoplasms / pathology

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  • (PMID = 18937709.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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32. Bair MJ, Lin IT, Chen HL, Wu CH: Pseudomyxoma peritonei. Am J Med Sci; 2010 Oct;340(4):319
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Peritoneal Neoplasms / diagnosis. Pseudomyxoma Peritonei / diagnosis
  • [MeSH-minor] Appendiceal Neoplasms / pathology. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Rupture, Spontaneous / pathology

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  • (PMID = 20631610.001).
  • [ISSN] 1538-2990
  • [Journal-full-title] The American journal of the medical sciences
  • [ISO-abbreviation] Am. J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Marchiolé P, Di Capua E, Costantini S: A right latero-pelvic mass: an uncommon diagnosis by endovaginal ultrasonography. Mucocele of the appendix. Acta Obstet Gynecol Scand; 2006;85(8):1014-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A right latero-pelvic mass: an uncommon diagnosis by endovaginal ultrasonography. Mucocele of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / ultrasonography. Cystadenoma, Mucinous / ultrasonography

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  • (PMID = 16862486.001).
  • [ISSN] 0001-6349
  • [Journal-full-title] Acta obstetricia et gynecologica Scandinavica
  • [ISO-abbreviation] Acta Obstet Gynecol Scand
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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34. Miller JS, Ramalingam P, Wang BY, Lee JR: Appendiceal mass in a middle-aged woman. Endometrioid endometrial carcinoma metastatic to the appendix. Arch Pathol Lab Med; 2006 Mar;130(3):407-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appendiceal mass in a middle-aged woman. Endometrioid endometrial carcinoma metastatic to the appendix.
  • [MeSH-major] Appendiceal Neoplasms / secondary. Carcinoma, Endometrioid / secondary
  • [MeSH-minor] Adenocarcinoma / pathology. Biomarkers, Tumor / analysis. Diagnosis, Differential. Endometrial Neoplasms / chemistry. Endometrial Neoplasms / pathology. Endometrial Neoplasms / surgery. Female. Humans. Middle Aged. Proto-Oncogene Proteins c-bcl-2 / analysis. Receptors, Estrogen / analysis. Vimentin / analysis

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  • (PMID = 16519577.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Receptors, Estrogen; 0 / Vimentin
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35. Karabulut R, Sönmez K, Türkyilmaz Z, Yilmaz Y, Akyürek N, Başaklar AC, Kale N: Mucosa-associated lymphoid tissue lymphoma in the appendix, a lead point for intussusception. J Pediatr Surg; 2005 May;40(5):872-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucosa-associated lymphoid tissue lymphoma in the appendix, a lead point for intussusception.
  • Abstract Appendiceal intussusception and mucosa-associated lymphoid tissue lymphoma are both uncommon entities, and this is the first report of the two occurring concomitantly in an 8-year-old boy.
  • This report of a mucosa-associated lymphoid tissue lymphoma localized in the appendix has not been reported previously.
  • [MeSH-major] Appendiceal Neoplasms / complications. Cecal Diseases / etiology. Intussusception / etiology. Lymphoma, B-Cell, Marginal Zone / complications. Lymphoma, Non-Hodgkin / complications

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  • (PMID = 15937835.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Byrn JC, Wang JL, Divino CM, Nguyen SQ, Warner RR: Management of goblet cell carcinoid. J Surg Oncol; 2006 Oct 1;94(5):396-402
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND AND OBJECTIVES: Goblet cell carcinoid, a rare tumor of intermediate malignant potential, is known to account for a significant minority of appendiceal neoplasms.
  • Presenting diagnoses included appendicitis (n=8), abdominal or liver mass (n=5), uterine fibroids (n=1), ovarian mass (n=1), and Crohn's Disease exacerbation (n=1).
  • Patients were divided into two groups: those where the diagnosis was an incidental finding at operation (Group 1) and those where the presentation was of an abdominal mass or metastatic disease (Group 2).
  • CONCLUSIONS: Goblet cell carcinoid is a rare malignant tumor largely affecting the appendix.
  • In patients presenting with appendicitis, our series does not support the recommendation of right hemicolectomy based on pathologic diagnosis alone and surgical intervention must be customized to the individual patient.
  • [MeSH-major] Appendiceal Neoplasms / therapy. Carcinoid Tumor / therapy. Gastrointestinal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Appendectomy. Appendicitis / complications. Appendicitis / surgery. Colectomy. Female. Humans. Incidental Findings. Liver Neoplasms / diagnosis. Male. Middle Aged. Ovarian Neoplasms / diagnosis. Retrospective Studies. Uterine Neoplasms / diagnosis

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  • [Copyright] Copyright (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16967437.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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37. Macher-Goeppinger S, Longerich T, Hackert T, Andrulis M: Expect the unexpected. Int J Surg Pathol; 2010 Aug;18(4):301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Endocrine Gland Neoplasms / diagnosis. Lymphoma, Large B-Cell, Diffuse / diagnosis. Neoplasm Invasiveness / diagnosis
  • [MeSH-minor] Aged. Appendectomy. Biomarkers, Tumor / metabolism. Blood Vessels / pathology. Diagnosis, Differential. Female. Humans. Neoplasms, Multiple Primary

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  • (PMID = 20627955.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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38. Tran TA, Holloway RW, Finkler NJ: Metastatic appendiceal mucinous adenocarcinoma to well-differentiated diffuse mesothelioma of the peritoneal cavity: a mimicker of florid mesothelial hyperplasia in association with neoplasms. Int J Gynecol Pathol; 2008 Oct;27(4):526-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic appendiceal mucinous adenocarcinoma to well-differentiated diffuse mesothelioma of the peritoneal cavity: a mimicker of florid mesothelial hyperplasia in association with neoplasms.
  • Atypical/florid mesothelial hyperplasia associated with another neoplastic process is not an infrequent phenomenon and has been reported in a variety of tumors.
  • The subsequent operation, however, demonstrated a mucinous neoplasm of the appendix with involvement of the peritoneal cavity in the form of peritoneal mucinous carcinomatosis as well as metastases to the uterine serosa and adnexal surfaces.
  • Microscopic analysis revealed an appendiceal adenocarcinoma with signet-ring-cell features that has metastasized to a diffuse well-differentiated mesothelioma of the peritoneal cavity.
  • To the best of our knowledge, this is the first report of a metastatic appendiceal mucinous adenocarcinoma to a well-differentiated diffuse mesothelioma of the peritoneal cavity.
  • This unusual case report expands the spectrum of mesothelial proliferation in conjunction with a malignant neoplasm and serves to remind pathologists that such a concomitant occurrence exists.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Appendiceal Neoplasms / pathology. Mesothelioma / pathology. Peritoneal Neoplasms / secondary
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Histocytochemistry. Humans

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  • (PMID = 18753969.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Castellanos JA, Edwards CM, Shaver A, Merchant NB, Parikh AA: Appendiceal adenocarcinoma presenting as venous thromboembolism: an unusual presentation of a rare carcinoma. Am Surg; 2010 May;76(5):543-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appendiceal adenocarcinoma presenting as venous thromboembolism: an unusual presentation of a rare carcinoma.
  • [MeSH-major] Adenocarcinoma / complications. Adenocarcinoma / diagnosis. Appendiceal Neoplasms / complications. Appendiceal Neoplasms / diagnosis. Venous Thromboembolism / etiology
  • [MeSH-minor] Humans. Male. Middle Aged. Thrombophilia / diagnosis. Thrombophilia / etiology. Thrombophilia / therapy

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  • [Cites] Ann Surg. 2001 Aug;234(2):198-205 [11505065.001]
  • [Cites] Br J Surg. 2004 Mar;91(3):304-11 [14991630.001]
  • [Cites] J Surg Oncol. 2004 Sep 15;87(4):162-6 [15334630.001]
  • [Cites] Ann Surg Oncol. 2008 Sep;15(9):2426-32 [18521686.001]
  • (PMID = 20506889.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / T32 CA106183
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS619862; NLM/ PMC4157457
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40. Sugarbaker PH: The natural history, gross pathology, and histopathology of appendiceal epithelial neoplasms. Eur J Surg Oncol; 2006 Aug;32(6):644-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The natural history, gross pathology, and histopathology of appendiceal epithelial neoplasms.
  • AIM: To report the pathology of appendiceal epithelial neoplasms a review of the Washington Cancer Institute experience and a PubMed literature search was performed.
  • FINDINGS: Epithelial appendiceal neoplasms present a significant oncologic challenge.
  • CONCLUSIONS: Appendiceal epithelial neoplasms should be regarded as a distinct clinical entity with special clinical treatments used for optimal management.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Adenoma / pathology. Appendiceal Neoplasms / pathology

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  • (PMID = 16621426.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 17
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41. Skrovina M, Czudek S, Bartos J, Ferák I, Adamcík L, Bezunková E, Vanko R: [The Peutz-Jeghers syndrome--a case review]. Rozhl Chir; 2007 Jan;86(1):24-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The patient who presented with insignificant family history with a diagnosed stenosing tumor of his appendix and histological findings of highly suspected adenocarcinoma, was indicated for surgical revision and right-sided hemicolectomy.
  • The final histological finding diagnosed solitary hamartoma of the Peutz-Jeghers polyp.
  • [MeSH-major] Diagnostic Errors. Hamartoma / diagnosis. Intestinal Polyps / diagnosis. Peutz-Jeghers Syndrome / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Adult. Appendiceal Neoplasms / diagnosis. Appendiceal Neoplasms / surgery. Humans. Male

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  • (PMID = 17416075.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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42. Kulkarni D, Pinto DJ: Coexistence of Crohn's disease and neuroendocrine tumour of appendix: more than coincidence? Int J Clin Pract; 2005 Jul;59(7):852-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coexistence of Crohn's disease and neuroendocrine tumour of appendix: more than coincidence?
  • [MeSH-major] Appendiceal Neoplasms / complications. Carcinoma, Neuroendocrine / complications. Crohn Disease / complications

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  • (PMID = 15963215.001).
  • [ISSN] 1368-5031
  • [Journal-full-title] International journal of clinical practice
  • [ISO-abbreviation] Int. J. Clin. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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43. Legendre H, Delaunoit T, Chassaing C, Pector JC: [Treatment of peritoneal carcinomatosis from colorectal and appendiceal cancer by extensive cytoreductive surgery combined with hyperthermic intraoperative intraperitoneal chemotherapy]. Rev Med Brux; 2005 Sep-Oct;26(5):439-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment of peritoneal carcinomatosis from colorectal and appendiceal cancer by extensive cytoreductive surgery combined with hyperthermic intraoperative intraperitoneal chemotherapy].
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Appendiceal Neoplasms / pathology. Carcinoma / drug therapy. Carcinoma / secondary. Colorectal Neoplasms / pathology. Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / secondary

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  • (PMID = 16318097.001).
  • [ISSN] 0035-3639
  • [Journal-full-title] Revue médicale de Bruxelles
  • [ISO-abbreviation] Rev Med Brux
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Belgium
  • [Number-of-references] 43
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44. Santos LD, Kennerson A, Killingsworth M: Appendiceal mixed endocrine-exocrine neoplasm presenting as bilateral solid tubular and classical Krukenberg tumour. Pathology; 2007 Feb;39(1):169-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appendiceal mixed endocrine-exocrine neoplasm presenting as bilateral solid tubular and classical Krukenberg tumour.
  • [MeSH-major] Adenocarcinoma / secondary. Appendiceal Neoplasms / pathology. Krukenberg Tumor / secondary. Neuroendocrine Tumors / pathology. Ovarian Neoplasms / secondary
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Microscopy, Electron, Transmission

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  • (PMID = 17365834.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
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45. Hwang JH, So KA, Modi G, Lee JK, Lee NW, Lee KW, Kim I: Borderline-like mucinous tumor arising in mature cystic teratoma of the ovary associated with pseudomyxoma peritonei. Int J Gynecol Pathol; 2009 Jul;28(4):376-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Borderline-like mucinous tumor arising in mature cystic teratoma of the ovary associated with pseudomyxoma peritonei.
  • SUMMARY: Pseudomyxoma peritonei (PMP) is now considered to originate from appendiceal mucinous neoplasms in almost all cases.
  • However, a mucinous neoplasm arising in a mature cystic teratoma is rarely responsible for PMP.
  • We herein report 2 cases of PMP associated with borderline mucinous tumors arising in mature cystic teratoma.
  • Both ovarian borderline mucinous tumors were morphologically and immunohistochemically similar to the secondary tumors from appendiceal origin, and PMP was histologically similar to peritoneal adenomucinosis.
  • [MeSH-major] Cystadenocarcinoma, Mucinous / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology. Teratoma / pathology

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  • (PMID = 19483624.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Karaca G, Koçak E, Pekici R, Güler O, Köklü S: A rare cause of acute appendicitis: cystic lymphangioma. Am Surg; 2010 Sep;76(9):E150-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Appendiceal Neoplasms / complications. Appendicitis / etiology. Appendicitis / surgery. Lymphangioma, Cystic / complications
  • [MeSH-minor] Abdomen, Acute / diagnosis. Abdomen, Acute / etiology. Adult. Appendectomy / methods. Biopsy, Needle. Emergency Service, Hospital. Follow-Up Studies. Humans. Immunohistochemistry. Male. Rare Diseases. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 21396267.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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47. Lee YT, Wu HS, Hung MC, Lin ST, Hwang YS, Huang MH: Ruptured appendiceal cystadenoma presenting as right inguinal hernia in a patient with left colon cancer: a case report and review of literature. BMC Gastroenterol; 2006;6:32
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  • [Title] Ruptured appendiceal cystadenoma presenting as right inguinal hernia in a patient with left colon cancer: a case report and review of literature.
  • BACKGROUND: Mucoceles resulting from cystadenomas of the appendix are uncommon.
  • There are several reports associating colonic malignancy with cystadenomas of the appendix.
  • CASE PRESENTATION: A case of ruptured mucocele resulting from cystadenoma of the appendix was presented as right inguinal hernia in a 70-year-old male.
  • CONCLUSION: Synchronous colon cancer may occur in patients with appendiceal mucoceles.
  • [MeSH-major] Adenocarcinoma. Appendiceal Neoplasms / complications. Colonic Neoplasms. Cystadenoma / complications. Hernia, Inguinal / etiology. Mucocele / complications. Neoplasms, Second Primary
  • [MeSH-minor] Aged. Appendectomy. Colectomy. Debridement. Humans. Male. Peritoneal Neoplasms / surgery. Pseudomyxoma Peritonei / surgery. Rupture, Spontaneous. Treatment Outcome

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  • (PMID = 17074081.001).
  • [ISSN] 1471-230X
  • [Journal-full-title] BMC gastroenterology
  • [ISO-abbreviation] BMC Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 27
  • [Other-IDs] NLM/ PMC1634861
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48. Mandal S, Kawatra V, Khurana N: Mucinous cystadenocarcinoma arising in mature cystic teratoma ovary and associated pseudomyxoma peritonei: report of a case. Arch Gynecol Obstet; 2008 Sep;278(3):265-7
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  • Pseudomyxoma peritonei (PMP) is most commonly associated with intra-abdominal spread of an appendiceal mucinous neoplasm and very rarely seen in cases of primary ovarian tumours.
  • [MeSH-major] Cystadenocarcinoma, Mucinous / pathology. Ovarian Neoplasms / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology. Teratoma / pathology

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  • (PMID = 18293005.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CA-125 Antigen
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49. Cabanas J, Gomes da Silva R, Goldstein P, Verghese M, Sugarbaker PH: Recurrence of pseudomyxoma peritonei within the inguinal canal. Tumori; 2005 Nov-Dec;91(6):481-6
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  • AIM AND BACKGROUND: Tumor appearing in an inguinal hernia sac indicates widespread carcinomatosis with ascites.
  • A new onset hernia is a common clinical presentation of pseudomyxoma peritonei syndrome arising in an appendiceal mucinous tumor.
  • We present five patients with a recurrence of pseudomyxoma peritonei tumor nodules in the inguinal region following cytoreductive surgery and attempt to understand the etiology of this treatment failure.
  • METHODS AND STUDY DESIGN: From a database of 910 patients with mucinous appendiceal tumors with peritoneal dissemination who had definitive treatment, five patients who had disease recurrence within the inguinal region were identified.
  • RESULTS: Five patients with ages ranging 39 to 67 years had a mucinous tumor in the inguinal region as a recurrence after a previous cytoreductive surgery combined with perioperative intraperitoneal chemotherapy.
  • All these patients were made disease-free by the reoperative surgery with a sacrifice of the testicle in four.
  • [MeSH-major] Adenocarcinoma, Mucinous. Hernia, Inguinal / etiology. Inguinal Canal. Neoplasm Recurrence, Local. Peritoneal Neoplasms. Pseudomyxoma Peritonei

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  • (PMID = 16457146.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Koff JM, Choi JR, Hwang I: Inverted appendiceal orifice masquerading as a cecal polyp on virtual colonoscopy. Gastrointest Endosc; 2005 Aug;62(2):308; discussion 308
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  • [Title] Inverted appendiceal orifice masquerading as a cecal polyp on virtual colonoscopy.
  • [MeSH-major] Appendix / diagnostic imaging. Cecal Neoplasms / diagnostic imaging. Colonography, Computed Tomographic. Intestinal Polyps / diagnostic imaging
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged

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  • [CommentIn] Gastrointest Endosc. 2006 Feb;63(2):358 [16427964.001]
  • (PMID = 16047004.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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51. Smaldone GM, Richard SD, Krivak TC, Kelley JL 3rd, Edwards RP: Pregnancy after tumor debulking and intraperitoneal cisplatin for appendiceal carcinoid tumor. Obstet Gynecol; 2007 Aug;110(2 Pt 2):477-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pregnancy after tumor debulking and intraperitoneal cisplatin for appendiceal carcinoid tumor.
  • CASE: We present the case of a 25-year-old woman with appendiceal carcinoid tumor treated with intraperitoneal cisplatin for peritoneal recurrence after a fertility-sparing cytoreductive procedure.
  • She subsequently had a successful second pregnancy and is currently alive without evidence of her disease.
  • CONCLUSION: Conception is possible after tumor debulking and intraperitoneal chemotherapy.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Appendiceal Neoplasms / drug therapy. Carcinoid Tumor / drug therapy. Cisplatin / adverse effects. Infertility, Female / therapy. Neoplasm Recurrence, Local / drug therapy


52. Lu IT, Ko CW, Chang CS, Hou TC: Asymptomatic intussusception secondary to a giant appendiceal mucocele treated via a laparoscopic approach. Gastrointest Endosc; 2009 Nov;70(5):1026-7; discussion 1027
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  • [Title] Asymptomatic intussusception secondary to a giant appendiceal mucocele treated via a laparoscopic approach.
  • [MeSH-major] Appendectomy / methods. Appendiceal Neoplasms / complications. Colon / surgery. Ileum / surgery. Intussusception / etiology. Laparoscopy / methods. Mucocele / complications
  • [MeSH-minor] Anastomosis, Surgical. Colonoscopy. Diagnosis, Differential. Humans. Male. Middle Aged. Severity of Illness Index. Tomography, X-Ray Computed

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  • (PMID = 19595314.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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53. Hibi K, Mizutani M, Imazawa M, Nakamura T, Nonoyama M, Shibata H: Mucinous cystadenoma of the appendix associated with muscular and neuromatous hyperplasia: report of a case. Nagoya J Med Sci; 2008 Mar;70(1-2):35-40
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  • [Title] Mucinous cystadenoma of the appendix associated with muscular and neuromatous hyperplasia: report of a case.
  • Mucinous cystadenoma of the appendix is a type of appendiceal mucocele and a rather rare condition usually found incidentally in the course of other abdominal surgery.
  • A previous evaluation of 73 appendiceal mucoceles showed that this disease was often associated with adenocarcinoma and other epithelial atypia.
  • This observation suggested that patients with mucinous cystadenoma of the appendix also have some underlying disorders.
  • However, non-epithelial changes associated with appendiceal mucocele have not been reported so far.
  • In this study, we presented for the first time a mucinous cystadenoma of the appendix associated with muscular and neuromatous hyperplasia.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Cystadenoma, Mucinous / pathology. Muscle, Smooth / pathology

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  • (PMID = 18807294.001).
  • [ISSN] 0027-7622
  • [Journal-full-title] Nagoya journal of medical science
  • [ISO-abbreviation] Nagoya J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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54. Brustmann H: Myxoglobulosis of the appendix associated with a proximal carcinoid and a pseudodiverticulum. Ann Diagn Pathol; 2006 Jun;10(3):166-8
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  • [Title] Myxoglobulosis of the appendix associated with a proximal carcinoid and a pseudodiverticulum.
  • Intraoperatively, the appendix was enlarged and distended.
  • The lumen of the appendix was tightly filled with pearl-like globules, diagnostic of myxoglobulosis, a rare variant of mucocele of the appendix.
  • A carcinoid of 2.0 cm diameter was found in the proximal region of the appendix.
  • The appendiceal mucosa showed hyperplastic-adenomatous changes.
  • The latter may be an adjunct to the proximal partial obstruction of the appendiceal lumen by the carcinoid in the development of the spheroids of myxoglobulosis.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Appendix / pathology. Carcinoid Tumor / pathology. Diverticulum, Colon / pathology. Mucocele / pathology

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  • [ErratumIn] Ann Diagn Pathol. 2006 Aug;10(4):251
  • (PMID = 16730314.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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55. Sabnani I, Varguese J, Wascher R, Youngworth H, Tsang P: Multiple synchronous unusual extranodal sites of relapse in a patient with mantle cell lymphoma. Clin Adv Hematol Oncol; 2007 Oct;5(10):797-8,802; discussion 802-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Eye Neoplasms / pathology. Lymphoma, Mantle-Cell / pathology
  • [MeSH-minor] Aged. Appendiceal Neoplasms. Diagnostic Imaging. Eyelids / pathology. Female. Humans. Immunophenotyping. Lacrimal Apparatus / pathology. Recurrence

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  • (PMID = 17998897.001).
  • [ISSN] 1543-0790
  • [Journal-full-title] Clinical advances in hematology & oncology : H&O
  • [ISO-abbreviation] Clin Adv Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. In't Hof KH, van der Wal HC, Kazemier G, Lange JF: Carcinoid tumour of the appendix: an analysis of 1,485 consecutive emergency appendectomies. J Gastrointest Surg; 2008 Aug;12(8):1436-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoid tumour of the appendix: an analysis of 1,485 consecutive emergency appendectomies.
  • AIM: The aim of this study is to conduct a retrospective analysis of the incidence and long-term results of carcinoid tumours of the appendix in emergency appendectomies.
  • Four patients underwent ileocecal resection; one other patient underwent right hemicolectomy.
  • In none of the re-operation specimens was residual carcinoid tumour detected.
  • After a mean follow-up of 65 months (range, 25-92), all patients were alive and disease- and symptom-free.
  • CONCLUSION: Carcinoid tumours of the appendix most often present as acute appendicitis.
  • It also emphasises the value of histopathological analysis of every removed appendix.
  • The long-term prognosis of incidentally found carcinoids of the appendix is good.
  • [MeSH-major] Appendectomy / methods. Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery. Emergencies
  • [MeSH-minor] Adult. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • [Cites] Cancer. 2003 Feb 15;97(4):934-59 [12569593.001]
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  • (PMID = 18521695.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2491701
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57. Sambol E, Patterson D, Rivera R, Borys D, Greco MA, Kaul A, Nadler EP: An appendiceal leiomyoma in a child with acquired immunodeficiency syndrome. Pediatr Surg Int; 2006 Oct;22(10):865-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An appendiceal leiomyoma in a child with acquired immunodeficiency syndrome.
  • Included among these are smooth muscle neoplasms such as leiomyomas and leiomyosarcomas.
  • There have been at least 15 reported cases of smooth muscle tumors in the approximately 8,000 children with AIDS, however the incidence in immunocompetent children is only two per ten million.
  • She was ultimately found to have an appendiceal leiomyoma on abdominal exploration, the first reported case.
  • Our report suggests that smooth muscle tumors of the appendix be included in the differential diagnosis of abdominal masses in children with AIDS.
  • [MeSH-major] Acquired Immunodeficiency Syndrome / complications. Appendiceal Neoplasms / complications. Leiomyoma / complications
  • [MeSH-minor] Child. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Laparoscopy. Laparotomy. Tomography, X-Ray Computed


58. Murphy EM, Sexton R, Moran BJ: Early results of surgery in 123 patients with pseudomyxoma peritonei from a perforated appendiceal neoplasm. Dis Colon Rectum; 2007 Jan;50(1):37-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Early results of surgery in 123 patients with pseudomyxoma peritonei from a perforated appendiceal neoplasm.
  • PURPOSE: Epithelial appendiceal tumors are uncommon but can present as an emergency simulating appendicitis, or unexpectedly at laparotomy, laparoscopy, or on cross-sectional imaging.
  • We report the operative findings, pathologic assessment, and early outcomes in 123 consecutive patients with a perforated appendiceal neoplasm presenting as pseudomyxoma peritonei.
  • Complete tumor removal (cytoreduction) was attempted in selected patients and, if achieved, surgery was combined with intraoperative, intraperitoneal mitomycin C (10 mg/m(2)).
  • RESULTS: In total, 123 patients (52 males; 41 percent) underwent laparotomy for a perforated appendiceal malignancy presenting as pseudomyxoma peritonei.
  • Kaplan-Meier analysis of the 83 patients who had complete tumor removal predicted 75 percent disease-free survival at five years.
  • CONCLUSIONS: A perforated appendiceal epithelial tumor most frequently presents as pseudomyxoma peritonei.
  • This treatment strategy, involving surgery and intraperitoneal chemotherapy, can result in good outcomes in this rare and otherwise fatal disease.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / analysis. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Postoperative Complications. Rupture

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  • [CommentIn] Nat Clin Pract Gastroenterol Hepatol. 2007 Sep;4(9):490-1 [17667901.001]
  • (PMID = 17115339.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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59. Goere D, Elias D: [Appendiceal tumors found at appendectomy]. J Chir (Paris); 2009 Oct;146 Spec No 1:36-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Appendiceal tumors found at appendectomy].
  • [Transliterated title] Diagnostic de tumeur appendiculaire lors d'une appendicectomie.
  • There are three main histologic types of appendiceal tumor: adenoma, adenocarcinoma, and neuroendocrine tumor.
  • Neuroendocrine tumors (carcinoids) are by far the most common and account for two-third of all appendiceal tumors.
  • Rupture of any mucinous tumor-whether spontaneous or occurring during surgery-may result in pseudomyxoma peritonei; treatment of this condition requires complete resection of all lesions followed by hyperthermic intraperitoneal chemotherapy.
  • For unruptured appendiceal tumor, the appendix should be removed by a carcinologic right hemicolectomy if the tumor appears aggressive.
  • [MeSH-major] Appendectomy. Appendiceal Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Adenoma / diagnosis. Adenoma / surgery. Humans. Neuroendocrine Tumors / diagnosis. Neuroendocrine Tumors / surgery. Peritoneal Neoplasms / prevention & control. Pseudomyxoma Peritonei / prevention & control. Rupture / prevention & control

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  • (PMID = 19846099.001).
  • [ISSN] 0021-7697
  • [Journal-full-title] Journal de chirurgie
  • [ISO-abbreviation] J Chir (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 7
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60. Gusani NJ, Cho SW, Colovos C, Seo S, Franko J, Richard SD, Edwards RP, Brown CK, Holtzman MP, Zeh HJ, Bartlett DL: Aggressive surgical management of peritoneal carcinomatosis with low mortality in a high-volume tertiary cancer center. Ann Surg Oncol; 2008 Mar;15(3):754-63
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  • Common tumors treated with CS-HIPEC included appendiceal (38.5%), colorectal (24.6%), and ovarian cancers (13.1%), and peritoneal mesothelioma (12.3%).
  • The most favorable diagnosis was appendiceal cancer, for which 2-year survival was 66.7%, with lower-grade histologic subtypes of appendiceal cancer reaching 85.7% 2-year survival.
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Chemotherapy, Cancer, Regional Perfusion / methods. Peritoneal Neoplasms / surgery

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  • (PMID = 18080166.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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61. Dell'abate P, Del Rio P, Sommaruga L, Arcuri MF, Sianesi M: Laparoscopic treatment of sigmoid colon intussusception by large malignant tumor. Case report. G Chir; 2009 Aug-Sep;30(8-9):374-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic treatment of sigmoid colon intussusception by large malignant tumor. Case report.
  • The ileocolic or appendiceal types are more frequent compared to the colo-colic one.
  • We report successful laparoscopic left hemicolectomy in a patient with intussusception caused by a sigmoid tumor.
  • The laparoscopic approach was feasible because the dilation was moderate; however, if intussusception is due to cancer, laparoscopy can be safely performed if a correct and prompt diagnosis is achieved following oncologic criteria.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / surgery. Intussusception / pathology. Intussusception / surgery. Laparoscopy / methods. Sigmoid Neoplasms / pathology. Sigmoid Neoplasms / surgery

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  • (PMID = 19735619.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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62. Honnef I, Moschopulos M, Roeren T: Appendiceal mucinous cystadenoma. Radiographics; 2008 Sep-Oct;28(5):1524-7
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  • [Title] Appendiceal mucinous cystadenoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Appendiceal Neoplasms / diagnosis. Tomography, X-Ray Computed. Ultrasonography
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 18794324.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Salemis NS, Gourgiotis S, Pinialidis D, Sambaziotist D: Primary mucinous cystadenocarcinoma of the appendix: an unusual presentation of a rare tumor. J Dig Dis; 2008 Aug;9(3):175-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mucinous cystadenocarcinoma of the appendix: an unusual presentation of a rare tumor.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Cystadenocarcinoma, Mucinous / diagnosis

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  • (PMID = 18956597.001).
  • [ISSN] 1751-2972
  • [Journal-full-title] Journal of digestive diseases
  • [ISO-abbreviation] J Dig Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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64. Neves GR, Chapchap P, Sredni ST, Viana CR, Mendes WL: Childhood carcinoid tumors: description of a case series in a Brazilian cancer center. Sao Paulo Med J; 2006 Jan 5;124(1):21-5
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  • [Title] Childhood carcinoid tumors: description of a case series in a Brazilian cancer center.
  • CONTEXT AND OBJECTIVE: Carcinoid tumors are very rare both in children and adults.
  • About 85% of these tumors develop in the gastrointestinal tract.
  • The objective of the present study was to describe our experience with children treated of carcinoid tumors, and investigate the frequency morphological findings and results.
  • DESIGN AND SETTING: Report on case series, at the Department of Pediatrics of Centro de Tratamento e Pesquisa Hospital do Câncer, São Paulo.
  • METHODS: This was a retrospective analysis of clinical pathological data and outcomes among children (< 18 years old) with carcinoid tumors admitted from January 1, 1990, to December 31, 2001.
  • In eight cases (89%), the primary tumor site was the appendix and in one (11%) it was the left bronchus.
  • For those with primary tumor in the appendix, the main complaint was abdominal pain, which led to appendectomy.
  • Only one patient underwent right hemicolectomy due to tumor extension into the serosa.
  • The patient with bronchial tumor underwent left pneumonectomy.
  • All patients had localized disease and are alive and free of disease.
  • CONCLUSION: Although the majority of carcinoid tumors arise from the appendix, these tumors can also occur in other primary sites.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Carcinoid Tumor / pathology
  • [MeSH-minor] Adolescent. Brazil. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Neoplasm Invasiveness. Retrospective Studies. Sex Factors

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  • (PMID = 16612458.001).
  • [ISSN] 1516-3180
  • [Journal-full-title] São Paulo medical journal = Revista paulista de medicina
  • [ISO-abbreviation] Sao Paulo Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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65. Suppiah A, Barandiaran J, Morgan R, Perry EP: First case of villous adenoma of the appendix leading to acute appendicitis presenting as strangulated femoral hernia: changes in management owing to concurrent adenoma. Hernia; 2008 Feb;12(1):95-8
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  • [Title] First case of villous adenoma of the appendix leading to acute appendicitis presenting as strangulated femoral hernia: changes in management owing to concurrent adenoma.
  • Histology revealed acute inflammation and a villous adenoma of the appendix.
  • Villous adenomas of the vermiform appendix are extremely rare tumours of the gastrointestinal tract.
  • This is the first case combining two very rare pathologies--acute appendicitis presenting as strangulated femoral hernia and villous adenoma of the appendix.
  • Early diagnosis and surgery are required to avoid high morbidity of perforated appendicitis within a femoral hernia.
  • First, we discuss the diagnosis and surgical treatment of acute appendicitis within a femoral hernia.
  • [MeSH-major] Adenoma, Villous / complications. Appendiceal Neoplasms / complications. Appendicitis / diagnosis. Appendicitis / etiology. Hernia, Femoral / diagnosis

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  • (PMID = 17566835.001).
  • [ISSN] 1265-4906
  • [Journal-full-title] Hernia : the journal of hernias and abdominal wall surgery
  • [ISO-abbreviation] Hernia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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66. Thomas M, Basu N, Oke T, Yiu CY: Appendiceal polypectomy at colonoscopy. Dig Surg; 2009;26(2):121-2
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  • [Title] Appendiceal polypectomy at colonoscopy.
  • [MeSH-major] Adenoma / surgery. Appendiceal Neoplasms / surgery. Colonoscopy. Intestinal Polyps / surgery

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  • (PMID = 19262063.001).
  • [ISSN] 1421-9883
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
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67. Cakmak A, Karakayali F, Bayar S, Unal E, Akyol C, Kocaoğlu H: Pseudomyxoma retroperitonei presenting with a skin fistula. Turk J Gastroenterol; 2009 Mar;20(1):79-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Appendiceal Neoplasms / pathology. Cutaneous Fistula / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology

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  • (PMID = 19330745.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Turkey
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68. Davies JM, O'Neil B: Peritoneal carcinomatosis of gastrointestinal origin: natural history and treatment options. Expert Opin Investig Drugs; 2009 Jul;18(7):913-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Generally, PC has been treated similarly to metastatic cancers of the primary tumor, but associated with worse outcomes when compared to other sites of metastatic disease from the same primary tumor site.
  • OBJECTIVES: This paper outlines the natural history of PC, and surgical, chemotherapeutic, and combined modality treatment options, with a focus on PC of colorectal (CRC) and appendiceal origin.
  • As such, the optimal management strategies for both 'localized' and unresectable disease is unclear.
  • [MeSH-major] Carcinoma / secondary. Carcinoma / therapy. Gastrointestinal Neoplasms / therapy. Peritoneal Neoplasms / secondary. Peritoneal Neoplasms / therapy
  • [MeSH-minor] Animals. Clinical Trials as Topic / methods. Colorectal Neoplasms / drug therapy. Colorectal Neoplasms / surgery. Colorectal Neoplasms / therapy. Humans

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  • (PMID = 19548850.001).
  • [ISSN] 1744-7658
  • [Journal-full-title] Expert opinion on investigational drugs
  • [ISO-abbreviation] Expert Opin Investig Drugs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 27
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69. Omohwo C, Nieroda CA, Studeman KD, Thieme H, Kostuik P, Ross AS, Holter DR, Gushchin V, Merriman B, Sardi A: Complete cytoreduction offers longterm survival in patients with peritoneal carcinomatosis from appendiceal tumors of unfavorable histology. J Am Coll Surg; 2009 Sep;209(3):308-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Complete cytoreduction offers longterm survival in patients with peritoneal carcinomatosis from appendiceal tumors of unfavorable histology.
  • BACKGROUND: Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a rapidly evolving treatment for metastatic appendiceal neoplasms.
  • The aim of this study was to show the effect of complete cytoreduction (CC) on survival in patients undergoing CRS and HIPEC for high-grade appendiceal neoplasm.
  • STUDY DESIGN: A retrospective study of a prospective database of 56 patients (from 1999 to 2007) with appendiceal neoplasms treated with CRS and HIPEC was carried out.
  • Histology of the disease, CC score, and peritoneal cancer index (PCI) score were assessed independently and collectively for each group of patients.
  • Survival analysis by tumor histology was 80% for patients with low-grade tumors and 52% for patients with high-grade tumors (p = 0.024).
  • There was no statistically significant difference in survival between the low-grade and high-grade tumors when a complete cytoreduction was performed in both groups of patients: 80% versus 68% (p = 0.69).
  • CONCLUSIONS: CRS and HIPEC is an effective treatment for patients with disseminated appendiceal tumors.
  • High-grade tumors also benefit from this approach and should not be excluded from CRS and HIPEC.
  • Every effort should be made to achieve a complete cytoreduction regardless of the tumor histology.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Appendiceal Neoplasms / pathology. Hyperthermia, Induced. Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / secondary. Peritoneal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Chi-Square Distribution. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Neoplasm Staging. Proportional Hazards Models. Reoperation. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 19717034.001).
  • [ISSN] 1879-1190
  • [Journal-full-title] Journal of the American College of Surgeons
  • [ISO-abbreviation] J. Am. Coll. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor
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70. Lu SJ, Osmany S, Khoo JB, Ng DC: Synchronous adenocarcinoma of the appendix demonstrated on F-18 FDG PET/CT. Clin Nucl Med; 2010 Apr;35(4):256-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous adenocarcinoma of the appendix demonstrated on F-18 FDG PET/CT.
  • [MeSH-major] Adenocarcinoma / diagnosis. Appendiceal Neoplasms / diagnosis. Colorectal Neoplasms / diagnosis. Fluorodeoxyglucose F18. Neoplasms, Multiple Primary / diagnosis. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 20305414.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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71. Shen DP, Ni XZ, Yin XL, Wu ZY: Clinical and pathological features of follicular dendritic cell sarcoma of appendix: a case report. Chin Med J (Engl); 2009 Jul 5;122(13):1595-7
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  • [Title] Clinical and pathological features of follicular dendritic cell sarcoma of appendix: a case report.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Dendritic Cell Sarcoma, Follicular / pathology

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  • (PMID = 19719956.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / CR1 protein, human; 0 / Receptors, Complement 3b; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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72. Smeenk RM, Verwaal VJ, Antonini N, Zoetmulder FA: Survival analysis of pseudomyxoma peritonei patients treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Ann Surg; 2007 Jan;245(1):104-9
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  • SUMMARY BACKGROUND DATA: PMP is a clinical syndrome characterized by progressive intraperitoneal accumulation of mucous and mucinous implants, usually derived from a ruptured mucinous neoplasm of the appendix.
  • The median disease-free interval was 25.6 months (95% confidence interval [CI], 14.8-43.6 months).
  • The 3-year and 5-year disease-free survival probability was 43.6% (95% CI, 34.4%-55.2%) and 37.4% (95% CI, 28.2%-49.5%), respectively.
  • The disease-specific 3-year and 5-year survival probability was 70.9% (95% CI, 62.0%-81.2%) and 59.5% (95% CI 48.7%-72.5%), respectively.
  • Factors associated with survival were pathological subtype, completeness of cytoreduction, and degree and location of tumor load (P < 0.05).
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Hyperthermia, Induced. Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / surgery. Pseudomyxoma Peritonei / drug therapy. Pseudomyxoma Peritonei / surgery

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  • (PMID = 17197972.001).
  • [ISSN] 0003-4932
  • [Journal-full-title] Annals of surgery
  • [ISO-abbreviation] Ann. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Other-IDs] NLM/ PMC1867935
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73. Timofeev J, Galgano MT, Stoler MH, Lachance JA, Modesitt SC, Jazaeri AA: Appendiceal pathology at the time of oophorectomy for ovarian neoplasms. Obstet Gynecol; 2010 Dec;116(6):1348-53
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  • [Title] Appendiceal pathology at the time of oophorectomy for ovarian neoplasms.
  • OBJECTIVE: To investigate the prevalence of appendiceal pathology in women undergoing surgery for a suspected ovarian neoplasm and the predictive value of intraoperative findings to determine the need for appendectomy at the time of surgery.
  • Observations were stratified based on the nature (benign, borderline, or malignant) and histology (serous compared with mucinous) of the ovarian neoplasm, frozen compared with final pathological diagnosis, and the gross appearance of the appendix.
  • RESULTS: Among the 191 patients identified, frozen section was consistent with seven mucinous and 35 serous carcinomas, 16 serous and 33 mucinous borderline tumors, 71 mucinous and serous cystadenomas, and 29 cases of suspected metastatic tumor from a gastrointestinal primary.
  • The highest rates of coexisting appendiceal pathology were associated with serous ovarian cancers (94.4% of grossly abnormal and 35.3% of normal appendices) and ovarian tumors suspected to be of primary gastrointestinal origin (83.3% grossly abnormal and 60.0% normal appendices harbored coexisting mucinous neoplasms).
  • Linear regression analysis revealed that appearance of the appendix and frozen section diagnosis of the ovarian pathology were statistically significant predictors of coexisting appendiceal pathology, but the latter was more important.
  • CONCLUSION: The prevalence of coexisting, clinically significant appendiceal pathology is low with a frozen section diagnosis of serous or mucinous cystadenoma.
  • Appendectomy is recommended when frozen section diagnosis is mucinous or serous ovarian carcinoma, borderline tumor or metastatic carcinoma of suspected gastrointestinal origin.
  • [MeSH-major] Appendectomy. Ovarian Neoplasms / surgery. Ovariectomy
  • [MeSH-minor] Adult. Appendiceal Neoplasms / diagnosis. Appendiceal Neoplasms / secondary. Appendiceal Neoplasms / surgery. Appendix / pathology. Cecal Diseases / complications. Cecal Diseases / diagnosis. Cecal Diseases / surgery. Female. Frozen Sections. Humans. Middle Aged

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  • (PMID = 21099601.001).
  • [ISSN] 1873-233X
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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74. Yantiss RK, Shia J, Klimstra DS, Hahn HP, Odze RD, Misdraji J: Prognostic significance of localized extra-appendiceal mucin deposition in appendiceal mucinous neoplasms. Am J Surg Pathol; 2009 Feb;33(2):248-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic significance of localized extra-appendiceal mucin deposition in appendiceal mucinous neoplasms.
  • Appendiceal mucinous neoplasms confined to the mucosa are benign, whereas those with disseminated peritoneal mucin deposits often follow an indolent, but malignant, course.
  • Not infrequently, appendiceal mucinous neoplasms are associated with localized periappendiceal mucin deposits, but lack diffuse peritoneal involvement.
  • Although some investigators consider both acellular and cellular periappendiceal mucin to pose no, or minimal, risk for recurrent disease, the biologic importance of localized extra-appendiceal mucin has never been evaluated.
  • We identified 65 patients with appendiceal mucinous neoplasms, all of whom had localized periappendiceal mucin deposits without diffuse peritoneal involvement, and assessed them for the presence of extra-appendiceal epithelium and clinical outcome.
  • Most (77%) cases showed acellular periappendiceal mucin, but 15 (23%) had scant extra-appendiceal epithelium (range: 1 to 12 cell clusters).
  • Upon follow-up (mean: 48 mo), 2 (4%) patients with acellular periappendiceal mucin developed diffuse peritoneal disease, but neither of these appendices was submitted in total for histologic evaluation.
  • In contrast, 5 of 15 (33%) patients with cellular periappendiceal mucin developed mucinous ascites, including 1 who eventually died of disease (P=0.03).
  • Thus, patients with appendiceal mucinous neoplasms and acellular periappendiceal mucin are unlikely to develop recurrent disease.
  • However, microscopic examination of the entire appendix is necessary, as lesions with extra-appendiceal tumor cells are more likely to progress to disseminated disease and result in death of the patient, even if the mucin is paucicellular and confined to the periappendiceal region.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Appendiceal Neoplasms / pathology. Mucins / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Prognosis

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  • (PMID = 18852679.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucins
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75. Bair MJ, Lee PH, Chan YJ: Urologic manifestations of acute appendicitis secondary to metastatic cervical cancer. J Formos Med Assoc; 2007 Sep;106(9):784-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acute appendicitis, a common entity in differential diagnosis, may present with diverse clinical manifestations.
  • Computed tomography revealed an enlarged appendix surrounded by an abscess, and appendectomy was performed.
  • Pathologic examination of the surgical specimen revealed metastatic cervical cancer in the appendix.
  • Patients with acute appendicitis may manifest with urologic disorders that can be caused by metastatic tumor.


76. Persaud T, Swan N, Torreggiani WC: Giant mucinous cystadenoma of the appendix. Radiographics; 2007 Mar-Apr;27(2):553-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant mucinous cystadenoma of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Cystadenoma, Mucinous / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed. Venous Thrombosis / diagnosis

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  • (PMID = 17374868.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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77. Lochman P, Cáp R, Kohout A: Adenocarcinoma of the appendix and a Meckel's diverticulum in a case of acute appendicitis. Onkologie; 2007 Sep;30(8-9):457-8
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  • [Title] Adenocarcinoma of the appendix and a Meckel's diverticulum in a case of acute appendicitis.
  • [MeSH-major] Adenocarcinoma / complications. Adenocarcinoma / diagnosis. Appendiceal Neoplasms / complications. Appendiceal Neoplasms / diagnosis. Appendicitis / complications. Appendicitis / diagnosis. Meckel Diverticulum / complications. Meckel Diverticulum / diagnosis

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  • (PMID = 17848820.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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78. Gordon R, Burns K, Friedlich M: Goblet cell carcinoid of the appendix. Can J Surg; 2005 Jun;48(3):251-2
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  • [Title] Goblet cell carcinoid of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery

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  • [Cites] Surg Gynecol Obstet. 1988 Jul;167(1):81-6 [3289135.001]
  • [Cites] Int Surg. 1989 Apr-Jun;74(2):109-10 [2753618.001]
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  • (PMID = 16013634.001).
  • [ISSN] 0008-428X
  • [Journal-full-title] Canadian journal of surgery. Journal canadien de chirurgie
  • [ISO-abbreviation] Can J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC3211548
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79. Ellis L, Shale MJ, Coleman MP: Carcinoid tumors of the gastrointestinal tract: trends in incidence in England since 1971. Am J Gastroenterol; 2010 Dec;105(12):2563-9
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  • [Title] Carcinoid tumors of the gastrointestinal tract: trends in incidence in England since 1971.
  • OBJECTIVES: The epidemiology of gastrointestinal neuroendocrine tumors (GI-NETs) is poorly understood.
  • Recent analyses have suggested changes in the incidence and distribution of such tumors, but have generally used data sets containing small patient numbers.
  • The anatomic distribution of tumors in the latest period analyzed was stomach 12%, small intestine 29%, appendix 38%, colon 13%, and rectum 8%.
  • The largest absolute increase in incidence was seen in the appendix (from 0.03 to 0.41 in men; from 0.05 to 0.59 in women).
  • Sex-specific incidence rates for gastric, colonic, and rectal NETs are similar, whereas appendiceal lesions were more common in females, and small intestinal tumors in men.
  • In view of the magnitude of these changes, particularly for gastric tumors, further studies to examine the underlying etiology of these changes are urgently indicated.
  • [MeSH-major] Carcinoid Tumor / epidemiology. Gastrointestinal Neoplasms / epidemiology. Neuroendocrine Tumors / epidemiology

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  • (PMID = 20823835.001).
  • [ISSN] 1572-0241
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / / 11700; United Kingdom / Cancer Research UK / / C1336 / A5735
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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80. Calişkan K, Yildirim S, Bal N, Nursal TZ, Akdur AC, Moray G: Mucinous cystadenoma of the appendix: a rare cause of acute abdomen. Ulus Travma Acil Cerrahi Derg; 2008 Oct;14(4):303-7
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  • [Title] Mucinous cystadenoma of the appendix: a rare cause of acute abdomen.
  • BACKGROUND: We aimed to assess the acute abdominal conditions due to appendiceal mucinous cystadenomas.
  • METHODS: We retrospectively evaluated 11 patients with histopathologically confirmed appendiceal mucinous cystadenoma.
  • RESULTS: The incidence of appendiceal mucinous cystadenoma was 0.95% of all appendectomy specimens reviewed.
  • The CT finding was well-encapsulated cystic mass in eight patients.
  • However, diagnosis is usually made intraoperatively or postoperatively on histopathological examination.
  • [MeSH-major] Abdomen, Acute / etiology. Appendiceal Neoplasms / complications. Appendiceal Neoplasms / surgery. Cystadenoma, Mucinous / complications. Cystadenoma, Mucinous / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Appendectomy. Colonoscopy / methods. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 18988054.001).
  • [ISSN] 1306-696X
  • [Journal-full-title] Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
  • [ISO-abbreviation] Ulus Travma Acil Cerrahi Derg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
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81. Van der Speeten K, Stuart OA, Mahteme H, Sugarbaker PH: A pharmacologic analysis of intraoperative intracavitary cancer chemotherapy with doxorubicin. Cancer Chemother Pharmacol; 2009 Apr;63(5):799-805
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  • METHODS: Twenty appendiceal malignancy patients with peritoneal carcinomatosis (PC), three appendiceal malignancy patients with direct extension into the pleural cavity, 20 patients with peritoneal mesothelioma and one patient with pleural mesothelioma were available for pharmacologic monitoring.
  • Tumor and normal tissues were obtained when available.
  • Doxorubicin concentrations in tumor tissue were consistently elevated above intraperitoneal concentrations from 30 through 90 min.
  • For appendiceal malignancy, the concentrations of doxorubicin were significantly higher in minimally aggressive mucinous tumors.
  • [MeSH-major] Antineoplastic Agents, Alkylating / therapeutic use. Appendiceal Neoplasms / drug therapy. Chemotherapy, Cancer, Regional Perfusion. Doxorubicin / therapeutic use. Mesothelioma / drug therapy. Peritoneal Neoplasms / drug therapy

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  • (PMID = 18654746.001).
  • [ISSN] 1432-0843
  • [Journal-full-title] Cancer chemotherapy and pharmacology
  • [ISO-abbreviation] Cancer Chemother. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 80168379AG / Doxorubicin
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82. Pan WD, Xue HD, Qin MW, Zhao RG, Liang JX: [Clinical, pathological and radiological characters of appendiceal mucocele]. Zhonghua Yi Xue Za Zhi; 2005 Aug 31;85(33):2354-7
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  • [Title] [Clinical, pathological and radiological characters of appendiceal mucocele].
  • OBJECTIVE: To improve capability of appendiceal mucocele diagnosis via analyzes its clinical, pathological basis and radiological results.
  • METHODS: Summarize 18 cases with pathological diagnosed appendiceal mucocele in PUMC Hospital since January 1985 till september 2004, including 4 males and 14 females (1:3.5), age ranged from 31 to 78 yrs old (average 59.8 years old).
  • (1) CLINICAL RESULTS: 8 cases (44.4%) had right lower abdominal pain, 12 cases (66.7%) had palpable abdominal mass. (2) Radiological results: barium enema showed extrinsic oppressed filling defect at the end of cecum without destruction of mucosa; CT scanning showed right lower abdominal cystic mass, 75% with cystic wall calcification, massive septal mucous ascites was seen in one case with pseudomyxoma peritonei; CT virtual colonography showed clearly the extra cavity and intracavity changes at cecum. (3) Pathological results: simple mucocele (4 cases, 22.2%), mucous cystadenoma (12 cases, 66.7%) and mucous cystadenocarcinoma (2 cases, 11.1%) CONCLUSION: There are four pathological types in appendiceal mucocele.
  • Radiological characters of appendiceal mucocele have distinct specificities while its clinical ones not.
  • Radiological procedures are vital for correct clinical diagnosis.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Mucocele / pathology

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  • (PMID = 16321230.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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83. Gillion JF, Franco D, Chapuis O, Serpeau D, Convard JP, Jullès MC, Balaton A, Karkouche B, Capelle P, Parmentier T, Chollet JM, Thillois JM, Berthelot G: [Appendiceal mucoceles, pseudomyxoma peritonei and appendiceal mucinous neoplasms: update on the contribution of imaging to choice of surgical approach]. J Chir (Paris); 2009 Apr;146(2):150-66
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  • [Title] [Appendiceal mucoceles, pseudomyxoma peritonei and appendiceal mucinous neoplasms: update on the contribution of imaging to choice of surgical approach].
  • [Transliterated title] Mucocèles appendiculaires, pseudomyxomes péritonéaux et tumeurs mucosécrétantes du carrefour iléocaecal: apport de l'imagerie dans la stratégie thérapeutique et le choix de la voie d'abord laparoscopique ou classique.
  • INTRODUCTION: The treatment of pseudomyxoma peritonei (PMPs) and appendiceal mucocele (AM) has changed radically.
  • Eleven patients had an intact AM, seven synchronous PMP (malignant appendiceal lesion in two of seven), six metachronous PMP (five with peritoneal mucinous carcinomatosis and one with diffuse peritoneal adenomucinosis) and three a ruptured AM but not PMP.
  • The incidence of mucin-secreting tumors observed (27 cases in 12 years in a region of 500 000 inhabitants) corresponds to a prevalence of approximately five cases per year per million inhabitants.
  • [MeSH-major] Adenocarcinoma, Mucinous / radiography. Appendiceal Neoplasms / radiography. Appendix / radiography. Mucocele / radiography. Peritoneal Neoplasms / radiography. Pseudomyxoma Peritonei / radiography

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  • [CommentIn] J Chir (Paris). 2009 Apr;146(2):167 [19540495.001]
  • (PMID = 19552906.001).
  • [ISSN] 0021-7697
  • [Journal-full-title] Journal de chirurgie
  • [ISO-abbreviation] J Chir (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Multicenter Study
  • [Publication-country] France
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84. Marte A, Sabatino MD, Cautiero P, Accardo M, Romano M, Parmeggiani P: Unexpected finding of laparoscopic appendectomy: appendix MALT lymphoma in children. Pediatr Surg Int; 2008 Apr;24(4):471-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unexpected finding of laparoscopic appendectomy: appendix MALT lymphoma in children.
  • We report on a case of MALT lymphoma involving the appendix in a 6-year-old girl.
  • A 6-year-old girl was referred to our institution in May 2005 with a diagnosis of appendicitis.
  • The appendix appeared moderately hyperaemic with slight enlargement of the two-thirds of the distal portion.
  • Further extensive examinations (abdominal MRI, gastroscopy, colonscopy and capsule endoscopy of the ileum) revealed that the lymphoma was limited to the distal two-third of the appendix (stage IA) and was not associated with any specific infection.
  • Appendiceal MALToma is a rather uncommon pathology and, to our knowledge, there is only one report of appendiceal intussusception associated with appendiceal maltoma.
  • [MeSH-major] Appendectomy. Appendiceal Neoplasms / pathology. Lymphoma, B-Cell, Marginal Zone / pathology

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  • (PMID = 17628810.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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85. Pai RK, Beck AH, Norton JA, Longacre TA: Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence. Am J Surg Pathol; 2009 Oct;33(10):1425-39
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence.
  • The classification and nomenclature of appendiceal mucinous neoplasms are controversial.
  • To determine the outcome for patients with appendiceal mucinous neoplasms and further evaluate whether they can be stratified into groups that provide prognostic information, the clinicopathologic features of 116 patients (66 with clinical follow-up) with appendiceal mucinous neoplasms were studied.
  • From a wide variety of histopathologic features assessed, the important predictors that emerged on univariate statistical analysis were presence of extra-appendiceal neoplastic epithelium (P=0.01), high-grade cytology (P<0.0001), architectural complexity (P<0.001), and invasion (P<0.001).
  • All 16 patients with mucinous neoplasms confined to the appendix and lacking high-grade cytology, architectural complexity, and invasion were alive with no recurrences at median 59 months follow-up (=mucinous adenoma).
  • One of 14 patients with low-grade cytology and acellular peritoneal mucin deposits developed recurrent tumor within the peritoneum at 45 months with no patient deaths to date (median, 48-mo follow-up) (=low-grade mucinous neoplasm with low risk of recurrence).
  • Twenty-seven patients with low-grade mucinous neoplasms with extra-appendiceal neoplastic epithelium had 1-year, 3-year, 5-year, and 10-year overall survival rates of 96%, 91%, 79%, and 46%, respectively, at median 53 months follow-up (=low-grade mucinous neoplasm with high risk of recurrence).
  • Three of the 4 patients with extra-appendiceal epithelium limited to the right lower quadrant developed full-blown peritoneal disease at 6, 41, and 99 months follow-up and 1 patient eventually died of disease.
  • Nine patients with appendiceal neoplasms with invasion or high-grade cytology and follow-up showed 1-year, 3-year, and 5-year overall survival rates of 86%, 57%, and 28% (=mucinous adenocarcinoma).
  • Appendiceal mucinous neoplasms can be stratified into 4 distinct risk groups on the basis of a careful histopathologic assessment of cytoarchitectural features and extent of disease at presentation.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Appendiceal Neoplasms / pathology. Neoplasm Recurrence, Local / epidemiology

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  • (PMID = 19641451.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NLM NIH HHS / LM / T15 LM007033
  • [Publication-type] Journal Article
  • [Publication-country] United States
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86. Freitas MS, Glick PL: Interval appendectomy for acute appendicitis. J Pediatr Surg; 2009 May;44(5):1056-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Abdominal Abscess / diagnosis. Abdominal Abscess / surgery. Acute Disease. Appendiceal Neoplasms / diagnosis. Crohn Disease / diagnosis. Diagnostic Errors. Drainage. Humans. Recurrence

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  • [CommentOn] J Pediatr Surg. 2008 Nov;43(11):1970-2 [18970926.001]
  • [CommentOn] J Pediatr Surg. 2007 Sep;42(9):1500-3 [17848238.001]
  • (PMID = 19433198.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
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87. Kunz J, Makek M: [Primary adenocarcinoma of the appendix as differential diagnosis of advanced ovarian carcinoma]. Praxis (Bern 1994); 2006 Aug 16;95(33):1217-25
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  • [Title] [Primary adenocarcinoma of the appendix as differential diagnosis of advanced ovarian carcinoma].
  • [Transliterated title] Das primäre Adenokarzinom der Appendix als Differentialdiagnose des fortgeschrittenen Ovarialkarzinoms.
  • Malignant tumours of the appendix are rare.
  • Metastatic mucinous adenocarcinomas of the appendix are only reported as case histories.
  • In clinical terms, the tumours usually manifest themselves as acute appendicitis, as ruptured appendicitis, as a tumour in the right lower abdominal quadrant or as a pelvic tumour, which are generally mistaken for an ovarian tumour with the same sonographic image.
  • Advanced primary adenocarcinomas of the appendix with ovarian metastases cannot be distinguished intraoperatively from a FIGO III ovarian carcinoma.
  • The pathologist makes the definitive diagnosis.
  • Surgical therapy of the isolated primary appendiceal carcinoma consists of a hemicolectomy--an appendectomy in favourable cases--and, in the case of a metastasised carcinoma, according to the guidelines for an advanced ovarian or colon carcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / secondary. Appendiceal Neoplasms / diagnosis. Carcinoma, Signet Ring Cell / diagnosis. Carcinoma, Signet Ring Cell / secondary. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / secondary
  • [MeSH-minor] Appendix / pathology. Appendix / surgery. Diagnosis, Differential. Female. Humans. Hysterectomy, Vaginal. Middle Aged. Omentum / pathology. Omentum / surgery. Ovary / pathology. Ovary / surgery. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / pathology. Peritoneal Neoplasms / secondary. Peritoneal Neoplasms / surgery. Peritoneum / pathology. Peritoneum / surgery. Postoperative Complications / diagnosis. Postoperative Complications / pathology. Postoperative Complications / surgery. Reoperation

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  • (PMID = 16939122.001).
  • [ISSN] 1661-8157
  • [Journal-full-title] Praxis
  • [ISO-abbreviation] Praxis (Bern 1994)
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Switzerland
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88. Thomas K, Timms J, Amin S: Enough evidence to abandon interval appendicectomy? Colorectal Dis; 2009 Jul;11(6):656
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Appendectomy / utilization. Appendiceal Neoplasms / diagnosis. Appendicitis / drug therapy. Appendicitis / surgery

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  • [CommentOn] Colorectal Dis. 2008 Jun;10(5):465-8 [17868409.001]
  • (PMID = 19220387.001).
  • [ISSN] 1463-1318
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
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89. Ng SC, Noursadeghi M, von Herbay A, Vaizey C, Pitcher MC, Flanagan KL: Cytomegalovirus ileitis associated with goblet cell carcinoid tumour of the appendix. J Infect; 2007 Mar;54(3):e153-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytomegalovirus ileitis associated with goblet cell carcinoid tumour of the appendix.
  • We report a female patient with cytomegalovirus (CMV) terminal ileitis and CMV viraemia, associated with a metastatic goblet cell carcinoid (GCC) tumour of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / complications. Carcinoid Tumor / complications. Cytomegalovirus / isolation & purification. Cytomegalovirus Infections / complications. Ileitis / complications. Ileitis / virology

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  • (PMID = 17049463.001).
  • [ISSN] 1532-2742
  • [Journal-full-title] The Journal of infection
  • [ISO-abbreviation] J. Infect.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antiviral Agents; P9G3CKZ4P5 / Ganciclovir
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90. Godfrey GJ, Bakkar R, Farghaly H: Mature cystic teratoma of the appendix: a case report. Anal Quant Cytol Histol; 2010 Oct;32(5):295-8
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  • [Title] Mature cystic teratoma of the appendix: a case report.
  • BACKGROUND: Teratomas very rarely arise from the appendix.
  • To our knowledge, only one prior case of mature teratoma involving the appendix has been reported in the medical literature.
  • CASE: Our case is the second reported case of mature cystic teratoma involving the appendix, and, to our knowledge, it is the first reported in a female who had two simultaneous teratomas, one arising from the appendix and one arising from the right ovary.
  • CONCLUSION: Although mature cystic teratoma is a rare tumor of the appendix, it should be considered in the differential diagnosis of appendiceal masses.
  • The differential diagnosis of appendiceal masses, including clinical and pathologic features, is discussed in detail.

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  • (PMID = 22043506.001).
  • [ISSN] 0884-6812
  • [Journal-full-title] Analytical and quantitative cytology and histology
  • [ISO-abbreviation] Anal. Quant. Cytol. Histol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Stewart JH 4th, Shen P, Russell G, Fenstermaker J, McWilliams L, Coldrun FM, Levine KE, Jones BT, Levine EA: A phase I trial of oxaliplatin for intraperitoneal hyperthermic chemoperfusion for the treatment of peritoneal surface dissemination from colorectal and appendiceal cancers. Ann Surg Oncol; 2008 Aug;15(8):2137-45
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  • [Title] A phase I trial of oxaliplatin for intraperitoneal hyperthermic chemoperfusion for the treatment of peritoneal surface dissemination from colorectal and appendiceal cancers.
  • Therefore, we undertook a phase I evaluation of IPHC with oxaliplatin for peritoneal dissemination from colorectal and appendiceal cancers to establish the dose-limiting toxicity (DLT) and the maximum tolerated dose (MTD).
  • Normal tissue and tumor samples were collected before and after the IPHC for analysis.
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Appendiceal Neoplasms / therapy. Colorectal Neoplasms / therapy. Organoplatinum Compounds / administration & dosage. Peritoneal Neoplasms / therapy

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  • [Cites] Clin Pharmacokinet. 2000 Jan;38(1):1-21 [10668856.001]
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  • [ErratumIn] Ann Surg Oncol. 2012 Jul;19(7):2421
  • (PMID = 18493824.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / K08 CA131482
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin
  • [Other-IDs] NLM/ NIHMS482983; NLM/ PMC3703640
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92. Dietrich CS 3rd, Desimone CP, Modesitt SC, Depriest PD, Ueland FR, Pavlik EJ, Kryscio R, Cibull M, Huh W, Partridge E, Numnum TM, Schilder J, Higgins RV, van Nagell JR 2nd: Primary appendiceal cancer: gynecologic manifestations and treatment options. Gynecol Oncol; 2007 Mar;104(3):602-6
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  • [Title] Primary appendiceal cancer: gynecologic manifestations and treatment options.
  • OBJECTIVE: To determine the presenting symptoms, gynecologic manifestations, and optimal intraoperative management of women with primary appendiceal cancer.
  • METHODS: A multi-institutional investigation was performed to identify female patients with primary appendiceal cancer who were treated from 1990 to present.
  • RESULTS: Forty-eight women with primary appendiceal cancer were identified from the tumor registries of participating institutions.
  • Ovarian involvement by metastatic appendiceal cancer was documented in 18 patients (38%).
  • Forty-one patients (85%) presented with advanced stage appendiceal cancer (Stage III or IV) and 19 patients (46%) received postoperative chemotherapy, most commonly with a combination of 5-FU/Leukovorin.
  • Following surgery, 22 patients (46%) experienced disease progression or recurrence, and 14 have died of disease.
  • CONCLUSION: Women with primary appendiceal cancer frequently present with ovarian metastases, and initial surgical intervention is often performed by a gynecologic oncologist.
  • The appendix should be examined intraoperatively, and if appendiceal carcinoma is identified, a right hemicolectomy and appropriate surgical staging should be considered.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Appendiceal Neoplasms / surgery. Ovarian Neoplasms / secondary. Ovarian Neoplasms / surgery

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  • [CommentIn] Gynecol Oncol. 2007 Dec;107(3):592; author reply 592-3 [17765296.001]
  • (PMID = 17055559.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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93. Elias D, Gilly F, Boutitie F, Quenet F, Bereder JM, Mansvelt B, Lorimier G, Dubè P, Glehen O: Peritoneal colorectal carcinomatosis treated with surgery and perioperative intraperitoneal chemotherapy: retrospective analysis of 523 patients from a multicentric French study. J Clin Oncol; 2010 Jan 1;28(1):63-8
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  • Patients with PC of appendiceal origin were excluded.
  • Five-year overall survival was 27%, and five-year disease-free survival was 10%.
  • Neither the grade of disease nor the presence of liver metastases had a significant prognostic impact.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Colorectal Neoplasms / therapy. Peritoneal Neoplasms / therapy

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  • [ErratumIn] J Clin Oncol. 2010 Apr 1;28(10):1808
  • (PMID = 19917863.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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94. Popovici A, Marinescu-Slatina D, Procopie I: [Pseudomyxoma of peritoneum. 1935]. Chirurgia (Bucur); 2010 May-Jun;105(3):393-6; discussion 397
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  • [MeSH-major] Appendiceal Neoplasms / history. Neoplasms, Multiple Primary / history. Ovarian Neoplasms / history. Peritoneal Neoplasms / history. Pseudomyxoma Peritonei / history
  • [MeSH-minor] Diagnosis, Differential. Female. History, 20th Century. Humans. Neoplasm Invasiveness. Romania. Treatment Outcome

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  • (PMID = 20726308.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Biography; Classical Article; Historical Article; Journal Article
  • [Publication-country] Romania
  • [Personal-name-as-subject] Popovici A; Marinescu-Slatina D; Procopie I
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95. Washington MK, Tang LH, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Members of the Cancer Committee, College of American Pathologists: Protocol for the examination of specimens from patients with neuroendocrine tumors (carcinoid tumors) of the appendix. Arch Pathol Lab Med; 2010 Feb;134(2):171-5
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  • [Title] Protocol for the examination of specimens from patients with neuroendocrine tumors (carcinoid tumors) of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Neuroendocrine Tumors / pathology
  • [MeSH-minor] Carcinoid Tumor / pathology. Carcinoid Tumor / surgery. Humans. Neoplasm Staging

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  • (PMID = 20121602.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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96. Ma KW, Chia NH, Yeung HW, Cheung MT: If not appendicitis, then what else can it be? A retrospective review of 1492 appendectomies. Hong Kong Med J; 2010 Feb;16(1):12-7
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  • Only 4.0% of the appendectomy specimens contained other appendiceal pathologies.
  • Appendiceal diverticulitis was the most common inflammatory pathology, contributing to 2.7% of all appendectomies, followed by granulomatous appendicitis.
  • Long-term follow-up should be offered to patients with granulomatous appendicitis and neoplastic appendiceal diseases.

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  • [CommentIn] Hong Kong Med J. 2010 Apr;16(2):158 [20354257.001]
  • (PMID = 20124568.001).
  • [ISSN] 1024-2708
  • [Journal-full-title] Hong Kong medical journal = Xianggang yi xue za zhi
  • [ISO-abbreviation] Hong Kong Med J
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 27
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97. Summers HG, Loftus EV Jr, Sebo TJ, Durski JM: Appendiceal carcinoid mimicking a Meckel's diverticulum on Tc-99m pertechnetate imaging. Clin Nucl Med; 2010 Apr;35(4):277-9
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  • [Title] Appendiceal carcinoid mimicking a Meckel's diverticulum on Tc-99m pertechnetate imaging.
  • [MeSH-major] Appendiceal Neoplasms / radionuclide imaging. Carcinoid Tumor / radionuclide imaging. Meckel Diverticulum / radionuclide imaging. Sodium Pertechnetate Tc 99m
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Radiopharmaceuticals

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  • (PMID = 20305424.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; A0730CX801 / Sodium Pertechnetate Tc 99m
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98. Bamboat ZM, Berger DL: Is right hemicolectomy for 2.0-cm appendiceal carcinoids justified? Arch Surg; 2006 Apr;141(4):349-52; discussion 352
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  • [Title] Is right hemicolectomy for 2.0-cm appendiceal carcinoids justified?
  • HYPOTHESIS: We believe right hemicolectomy (RHC) is not necessary in patients with an appendiceal carcinoid greater than 2.0 cm.
  • DESIGN: A retrospective review of patients with a histologically confirmed appendiceal carcinoid from April 1, 1980, to February 28, 2005, and an analysis of the literature.
  • PATIENTS: Forty-eight patients (34 females and 14 males) with a histologically confirmed diagnosis of appendiceal carcinoid were included in the study.
  • Appendiceal carcinoid was diagnosed incidentally in all 48 patients.
  • Postoperative follow-up and disease-free survival were confirmed in 33 patients via medical record review.
  • MAIN OUTCOME MEASURES: We assessed the relationship between survival, tumor size, and the role of RHC vs appendectomy alone.
  • RESULTS: Four patients in our series underwent secondary RHC and lymph node dissection for tumors greater than 2.0 cm, and none had positive lymph nodes.
  • CONCLUSION: Appendiceal carcinoids greater than 2.0 cm can be managed effectively with simple appendectomy, given their low malignant potential and slow growth, obviating the need for RHC in this group of patients without affecting overall survival.
  • [MeSH-major] Appendiceal Neoplasms / surgery. Carcinoid Tumor / surgery. Colectomy / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Appendectomy. Child. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Postoperative Complications. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 16618891.001).
  • [ISSN] 0004-0010
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Lee CK, Lee SH, Park JY, Lee TH, Chung IK, Park SH, Kim HS, Kim SJ: Appendiceal intussusception due to a fecalith mimicking a submucosal tumor. Endoscopy; 2009;41 Suppl 2:E25-6
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  • [Title] Appendiceal intussusception due to a fecalith mimicking a submucosal tumor.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Appendix / pathology. Calcinosis / complications. Fecal Impaction / complications. Intussusception / etiology
  • [MeSH-minor] Adult. Biopsy, Needle. Colonoscopy / methods. Diagnosis, Differential. Endoscopy / methods. Follow-Up Studies. Humans. Immunohistochemistry. Intestinal Mucosa / pathology. Male. Risk Assessment. Tomography, X-Ray Computed

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  • (PMID = 19219765.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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100. Basic-Jukic N, Furic-Cunko V, Coric M, Bubic-Filipi LJ, Kastelan Z, Pasini J, Kes P: Appendiceal carcinoid and mucinous cystadenoma in renal transplant recipients: case reports. Transplant Proc; 2010 Jun;42(5):1704-7
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  • [Title] Appendiceal carcinoid and mucinous cystadenoma in renal transplant recipients: case reports.
  • There is an increased incidence of tumors among renal transplant patients, which are associated with immunosuppression.
  • Carcinoids are rare neuroendocrine tumors that arise from the enterochromaffin cells.
  • Although appendiceal carcinoid tumors are the commonest malignant neoplasms affecting the appendix, and mucinous cystadenoma is the commonest benign appendiceal neoplasm, they have not been reported in immunosuppressed patients.
  • We present two renal transplant recipients who developed combined appendiceal carcinoid and mucinous cystadenoma.
  • [MeSH-major] Appendiceal Neoplasms / etiology. Cystadenoma, Mucinous / etiology. Kidney Transplantation / adverse effects
  • [MeSH-minor] Adult. Female. Humans. Kidney Failure, Chronic / surgery. Magnetic Resonance Imaging. Male. Neoplasms / epidemiology. Neoplasms / etiology. Neoplasms / pathology. Neoplasms / surgery. Ovarian Neoplasms / pathology. Ovarian Neoplasms / surgery

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  • (PMID = 20620505.001).
  • [ISSN] 1873-2623
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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