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36. Semino-Mora C, Liu H, McAvoy T, Nieroda C, Studeman K, Sardi A, Dubois A: Pseudomyxoma peritonei: is disease progression related to microbial agents? A study of bacteria, MUC2 AND MUC5AC expression in disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis. Ann Surg Oncol; 2008 May;15(5):1414-23
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  • BACKGROUND AND AIMS: Pseudomyxoma peritonei (PMP) is characterized by peritoneal tumors arising from a perforated appendiceal adenoma or adenocarcinoma, but associated entry of enteric bacteria in the peritoneum has not been considered as a cofactor.
  • METHODS: In situ hybridization was performed on resection specimens from five control subjects with noninflamed, nonperforated, non-neoplastic appendix and 16 patients with PMP [six with disseminated peritoneal adenomucinosis (DPAM) and 10 with peritoneal mucinous carcinomatosis (PMCA)].
  • CONCLUSIONS: Multiple enteric bacteria are present in PMP, and bacterial density and MUC2 expression is highest in the malignant form of PMP.

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  • (PMID = 18299935.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA082312-08; United States / NCI NIH HHS / CA / R01 CA082312; United States / NCI NIH HHS / CA / CA82312; United States / NCI NIH HHS / CA / R01 CA082312-08
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA Probes; 0 / MUC2 protein, human; 0 / MUC5AC protein, human; 0 / Mucin 5AC; 0 / Mucin-2; 0 / Mucins; 0 / RNA Probes
  • [Other-IDs] NLM/ NIHMS72052; NLM/ PMC2570966
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37. Kotani Y, Shiota M, Umemoto M, Tobiume T, Koike E, Shimaoka M, Takahashi Y, Kanemura K, Ishizu A, Hoshiai H: Laparoscopic mucin removal in patients with pseudomyxoma peritonei. JSLS; 2009 Apr-Jun;13(2):203-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND AND OBJECTIVES: Pseudomyxoma peritonei results from ovarian and appendiceal mucinous tumors.
  • In a recent Mayo Clinic report, the 5-year survival rate for this disease was 53% and the 10-year survival rate was 32%, while the Memorial Sloan-Kettering Cancer Center reported 5- and 10-year survival rates of 75% and 10%.

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  • (PMID = 19660216.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucins
  • [Other-IDs] NLM/ PMC3015933
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38. Tarrado X, Rodó J, Sepúlveda JA, García Aparicio L, Morales L: [Continent urinary diversion: the Mitrofanoff principle]. Cir Pediatr; 2005 Jan;18(1):32-5
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  • [Transliterated title] Derivación urinaria continente: principio de Mitrofanoff.
  • Complications found were: one appendicostomy prolapse, one appendix necrosis (that was then diverted with Casale's technique), one appendicular conduit stenosis and one case with catheterization difficulties that needed a tappering of the ileum conduit.

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  • (PMID = 15901106.001).
  • [ISSN] 0214-1221
  • [Journal-full-title] Cirugía pediátrica : organo oficial de la Sociedad Española de Cirugía Pediátrica
  • [ISO-abbreviation] Cir Pediatr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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39. Paredes Esteban RM, Muñoz Villanueva JR, Velasco Sánchez B, González Mariscal M, Rodríguez Vargas J, Martínez Sánchez M, García Ruiz M: [Role of the Helicobacter pylori in the aetiology of acute appendicitis. Preliminary studies]. Cir Pediatr; 2007 Jul;20(3):156-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Implicación del Helicobacter pylori en la etiopatogenia de la apendicitis aguda. Estudios preliminares.
  • In the group B, besides, appendix samples were tested for culture for H. pylori.
  • In the group B, besides, the culture of the appendix cecal was positive in 71.4%.
  • It seems that H. pylori colonizes the appendix in small proportion and is unlikely to be associated in direct correlation with acute appendicitis.

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  • (PMID = 18018743.001).
  • [ISSN] 0214-1221
  • [Journal-full-title] Cirugía pediátrica : organo oficial de la Sociedad Española de Cirugía Pediátrica
  • [ISO-abbreviation] Cir Pediatr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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40. Mrukowicz J, European Society for Paediatric Infectious Diseases (ESPID), European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN): Appendix I: methods for the development of evidence-based recommendations. J Pediatr Gastroenterol Nutr; 2008 May;46 Suppl 2:S49-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appendix I: methods for the development of evidence-based recommendations.

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  • (PMID = 18460972.001).
  • [ISSN] 1536-4801
  • [Journal-full-title] Journal of pediatric gastroenterology and nutrition
  • [ISO-abbreviation] J. Pediatr. Gastroenterol. Nutr.
  • [Language] eng
  • [Publication-type] Guideline; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Rotavirus Vaccines
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41. Mukhopadhyay M, Shukla RM, Mandal KC, Mukhopadhyay B: Renal teratoma with duplication of cecum and appendix. J Pediatr Surg; 2010 Jan;45(1):255-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Renal teratoma with duplication of cecum and appendix.
  • The tumor was removed successfully, and the patient had an uneventful recovery.
  • The tumor mass also had an appendix and cecum within the tumor, along with a normal appendix and cecum with a separate blood supply.
  • [MeSH-major] Appendix / abnormalities. Cecum / abnormalities

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20105615.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Ein SH, Langer JC, Daneman A: Nonoperative management of pediatric ruptured appendix with inflammatory mass or abscess: presence of an appendicolith predicts recurrent appendicitis. J Pediatr Surg; 2005 Oct;40(10):1612-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nonoperative management of pediatric ruptured appendix with inflammatory mass or abscess: presence of an appendicolith predicts recurrent appendicitis.
  • AIM OF STUDY: The aim of this study was to determine if the presence of an appendicolith is associated with an increased risk for recurrent appendicitis after nonoperative treatment of pediatric ruptured appendix with inflammatory mass or abscess.
  • [MeSH-major] Abdominal Abscess / complications. Appendicitis / etiology. Appendicitis / therapy. Appendix. Calculi / complications. Cecal Diseases / complications

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  • (PMID = 16226993.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Ndoye JM, Ndiaye A, Ndiaye A, Dia A, Fall B, Diop M, Sow ML: [Cadaveric topography and morphometry of the vermiform appendix]. Morphologie; 2005 Jun;89(285):59-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cadaveric topography and morphometry of the vermiform appendix].
  • [Transliterated title] Topographie et morphométrie cadavériques de l'appendice vermiculaire.
  • Our study justified by the frequency of acute appendicitis and the possibility of anatomic variations of the caecoappendicular area attempt to index the topographic variations of the vermiform appendix (v.a.).
  • We note also the level of implantation of this latter on the cecum, appearance of the mesoappendix and the distance separating the base of the appendix to the ileo-caecal junction.
  • Mac Burney's point permitted to localize appendix in 66%; the cecum has more often than not the form of a bulb (98.7%) and sited in right fossa iliaca.
  • The v.a. was more often in the form of worm with a long mesoappendix; his mean length was 106.4 mm (between 65 and 160 mm) and the mean diameter 6.77 mm (range between 4 and 10 mm).
  • The distance which separated the base of the appendix to the ileo-cecal junction varied between 15 to 40 mm with a mean distance of 24.2 mm.
  • In spite of scarcity of ectopic situation of the appendix for which laparoscopic approach is salutary, a similar topographic study during surgical treatment of acute appendicitis will be interesting.
  • [MeSH-major] Appendix / anatomy & histology. Cadaver

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  • (PMID = 16110740.001).
  • [ISSN] 1286-0115
  • [Journal-full-title] Morphologie : bulletin de l'Association des anatomistes
  • [ISO-abbreviation] Morphologie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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4
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4. Tumay V, Ozturk E, Ozturk H, Yilmazlar T: Appendiceal endometriosis mimicking acute appendicitis. Acta Chir Belg; 2006 Nov-Dec;106(6):712-3
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  • [Title] Appendiceal endometriosis mimicking acute appendicitis.
  • Appendiceal endometriosis is a rare and usually asymptomatic condition.
  • The histopathological result was endometriosis of the appendix vermiformis.
  • [MeSH-major] Appendix. Cecal Diseases / diagnosis. Endometriosis / diagnosis
  • [MeSH-minor] Acute Disease. Adult. Appendectomy. Appendicitis / diagnosis. Diagnosis, Differential. Female. Humans

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  • (PMID = 17290703.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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46. Yu B, Gastwirth JL: A method of assessing the sensitivity of the Cochran-Mantel-Haenszel test to an unobserved confounder. Philos Trans A Math Phys Eng Sci; 2008 Jul 13;366(1874):2377-88
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  • The computer code performing the sensitivity analysis is provided in appendix A.

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  • (PMID = 18407900.001).
  • [ISSN] 1364-503X
  • [Journal-full-title] Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
  • [ISO-abbreviation] Philos Trans A Math Phys Eng Sci
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z99 AG999999
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 63CZ7GJN5I / Allopurinol
  • [Other-IDs] NLM/ NIHMS54121; NLM/ PMC2446605
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47. Khan MR, Ahmed R, Saleem T: Intricacies in the surgical management of appendiceal mucinous cystadenoma: a case report and review of the literature. J Med Case Rep; 2010;4:129
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  • [Title] Intricacies in the surgical management of appendiceal mucinous cystadenoma: a case report and review of the literature.
  • INTRODUCTION: Mucinous cystadenoma is a type of mucocele of the appendix that is rarely encountered in clinical practice.
  • Computed tomography scan showed a mucocele of the appendix with minimal periappendiceal fat stranding.
  • Intra-operatively, a frozen section of the appendiceal sample was sent to ascertain the need for an extension of surgery to a right hemicolectomy.
  • The final histopathological examination showed a mucinous cystadenoma of the appendix.
  • A simple appendectomy using an intra-operative frozen section appears to be a reasonable surgical approach for selected cases with an intact mucocele of the appendix.

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  • (PMID = 20444269.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2873457
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48. Stewart JH 4th, Shen P, Russell G, Fenstermaker J, McWilliams L, Coldrun FM, Levine KE, Jones BT, Levine EA: A phase I trial of oxaliplatin for intraperitoneal hyperthermic chemoperfusion for the treatment of peritoneal surface dissemination from colorectal and appendiceal cancers. Ann Surg Oncol; 2008 Aug;15(8):2137-45
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  • [Title] A phase I trial of oxaliplatin for intraperitoneal hyperthermic chemoperfusion for the treatment of peritoneal surface dissemination from colorectal and appendiceal cancers.
  • A large body of literature suggests that oxaliplatin has excellent cytotoxicity against colorectal cancer.
  • Therefore, we undertook a phase I evaluation of IPHC with oxaliplatin for peritoneal dissemination from colorectal and appendiceal cancers to establish the dose-limiting toxicity (DLT) and the maximum tolerated dose (MTD).
  • Normal tissue and tumor samples were collected before and after the IPHC for analysis.
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Appendiceal Neoplasms / therapy. Colorectal Neoplasms / therapy. Organoplatinum Compounds / administration & dosage. Peritoneal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Chemotherapy, Cancer, Regional Perfusion. Combined Modality Therapy. Female. Humans. Hyperthermia, Induced / methods. Infusions, Parenteral. Male. Maximum Tolerated Dose. Middle Aged. Treatment Outcome

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  • (PMID = 18493824.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / K08 CA131482
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin
  • [Other-IDs] NLM/ NIHMS482983; NLM/ PMC3703640
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49. Modlin IM, Kidd M, Latich I, Zikusoka MN, Eick GN, Mane SM, Camp RL: Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed. Ann Surg; 2006 Jul;244(1):52-60
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  • [Title] Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed.
  • OBJECTIVE: To use differential gene expression of candidate markers to discriminate benign appendiceal carcinoids (APCs) from malignant and mixed cell APCs.
  • SUMMARY BACKGROUND DATA: Controversy exists in regard to the appropriate surgical management of APCs since it is sometimes difficult to predict tumor behavior using traditional pathologic criteria.
  • METHODS: Total RNA was isolated using TRIzol reagent from 42 appendiceal samples, including appendiceal carcinoids identified at exploration for appendicitis (no evidence of metastasis; n = 16), appendicitis specimens (n = 11), malignant appendiceal tumors (> 1.5 cm, evidence of metastatic invasion; n = 7), and mixed (goblet) cell appendiceal adenocarcinoids (n = 3), normal appendiceal tissue (n = 5), and 5 colorectal cancers.
  • RESULTS: CgA message was elevated (> 1000-fold, P < 0.05) in all tumor types.
  • NAP1L1 was elevated (> 10-fold, P < 0.03) in both malignant and goblet cell adenocarcinoids compared with normal and incidental lesions (P < 0.006).
  • MAGE-D2 and MTA1 message were significantly elevated (> 10-fold, P < 0.01) in the malignant and goblet cell adenocarcinoid tumors but not in the appendicitis-associated carcinoids or normal mucosa.
  • The apoptotic marker, NALP1, was overexpressed (> 50-fold, P < 0.05) in the appendicitis-associated and malignant appendiceal carcinoids but was significantly decreased (> 10-fold, P < 0.05) in the goblet cell adenocarcinoids.
  • Elevated CgA transcript and protein levels indicative of a carcinoid tumor were identified in one acute appendicitis sample with no histologic evidence of a tumor.
  • CONCLUSIONS: These data demonstrate that malignant APCs and goblet cell adenocarcinoids have elevated expression of NAP1L1, MAGE-D2, and MTA1 compared with appendiceal carcinoids identified at surgery for appendicitis.
  • This and the differences in NALP1 gene expression (decreased in goblet cell adenocarcinoids) provide a series of molecular signatures that differentiate carcinoids of the appendix.
  • CgA identified all appendiceal tumors as well as covert lesions, which may be more prevalent than previously recognized.
  • The molecular delineation of malignant appendiceal tumor potential provides a scientific basis to define the appropriate surgical management as opposed to morphologic assessment alone.

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  • (PMID = 16794389.001).
  • [ISSN] 0003-4932
  • [Journal-full-title] Annals of surgery
  • [ISO-abbreviation] Ann. Surg.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA097050; United States / NCI NIH HHS / CA / R01-CA-097050
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Antigens, Neoplasm; 0 / Apoptosis Regulatory Proteins; 0 / Biomarkers, Tumor; 0 / Cell Cycle Proteins; 0 / Chromogranin A; 0 / Chromogranins; 0 / Genetic Markers; 0 / MAGED2 protein, human; 0 / NAP1L1 protein, human; 0 / NLRP1 protein, human; 0 / Nuclear Proteins; 0 / Nucleosome Assembly Protein 1; 0 / Repressor Proteins; EC 3.5.1.- / Mta1 protein, human; EC 3.5.1.98 / Histone Deacetylases
  • [Other-IDs] NLM/ PMC1570599
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50. Yildiz F, Terzi A, Coban S, Zeybek N, Uzunkoy A: The handmade endoloop technique. A simple and cheap technique for laparoscopic appendectomy. Saudi Med J; 2009 Feb;30(2):224-7
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  • METHODS: We describe a modified technique, the handmade endoloop technique, for closing the base of the appendix.
  • RESULTS: The average price of material used for closing the base of appendix was 81 American Dollars (USD) for laparoscopic appendectomy with endoloop, and 8 USD for the technique described by this article.

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  • (PMID = 19198710.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
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51. Ruiz-Tovar J, Morales Castiñeiras V, García Teruel D, Sanjuanbenito Dehesa A, Lobo Martínez E, Martínez Molina E: Pseudomyxoma peritonei secondary to epithelial appendicular neoplasms. Experience in a non-specialised centre. Clin Transl Oncol; 2007 Nov;9(11):737-41
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  • INTRODUCTION: Pseudomyxoma peritonei is an infrequent entity, defined by collections of gelatinous material in the abdomen and pelvis and mucinous implants on peritoneum, secondary to the rupture of a mucinous lesion, usually of ovarian or appendiceal origin.
  • CT scan revealed a tumour in right iliac fossa in 4 patients, peritoneal enlargement in 1 and a liquid collection in 1.
  • Preoperative diagnosis was acute abdomen in 5 patients, peritoneal carcinomatosis in 3 and undetermined abdominal mass in 3.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Cystadenocarcinoma, Mucinous / pathology. Cystadenoma, Mucinous / pathology. Epithelial Cells / pathology. Neoplasms, Multiple Primary / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology

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  • (PMID = 18055329.001).
  • [ISSN] 1699-048X
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Journal Article
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52. Biyani DK, Benbow EW, Watson AJ: Diverticula of the appendix. Colorectal Dis; 2006 Nov;8(9):812-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diverticula of the appendix.
  • [MeSH-major] Appendix / pathology. Diverticulum / pathology

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  • (PMID = 17032331.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
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53. Sarin YK, Pathak D: Torsion of vermiform appendix. Indian Pediatr; 2006 Mar;43(3):266-7
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  • [Title] Torsion of vermiform appendix.
  • [MeSH-major] Appendix. Cecal Diseases
  • [MeSH-minor] Appendicitis / diagnosis. Appendicitis / surgery. Child. Humans. Male. Torsion Abnormality

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  • (PMID = 16585826.001).
  • [ISSN] 0019-6061
  • [Journal-full-title] Indian pediatrics
  • [ISO-abbreviation] Indian Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] India
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54. Barbagallo F, Latteri S, Sofia M, Ricotta A, Castello G, Chisari A, Randazzo V, La Greca G: Appendicular tuberculosis: the resurgence of an old disease with difficult diagnosis. World J Gastroenterol; 2010 Jan 28;16(4):518-21
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  • [Title] Appendicular tuberculosis: the resurgence of an old disease with difficult diagnosis.
  • Blind gut and ileum are the most common gastrointestinal localizations, while appendix involvement is infrequent.
  • Appendix involvement is usually related to symptoms of acute appendicitis since the caseous necrosis may lead to adhesions and surgical complications such as perforation.
  • For this reason patients with suspected appendicular TB usually undergo surgery even without a secure diagnosis.
  • In these cases, due to the absence of specific symptoms and signs, the diagnosis is delayed after surgery, thus resulting in a high percentage of important, and sometimes lethal, complications.
  • Histopathological examination is often the only way to reach a diagnosis and to establish specific antibiotic therapy, while an early diagnosis could avoid surgical treatment.
  • We report a case of appendicular TB not only for its rarity but also to discuss the difficulty in its diagnosis.
  • [MeSH-major] Appendicitis / diagnosis. Tuberculosis, Gastrointestinal / diagnosis

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  • (PMID = 20101782.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2811809
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55. Kajiwara R, Goto H, Yokosuka T, Yanagimachi M, Kuroki F, Fujii H, Takahashi H, Yokota S: [Acute appendicitis during bone marrow suppression following chemotherapy for acute leukemia; report of three cases]. Rinsho Ketsueki; 2007 Mar;48(3):223-8
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  • All patients had clinical features of fever, abdominal pain, and elevations of C-reactive protein.
  • Histological examinations of the appendectomy specimens showed infiltration of most of the lymphoid cells and a few neutrophils in the wall of the appendix.
  • Because of a high mortality rate after appendix perforation, immediate surgical intervention with sufficient perioperative support should be performed.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Appendicitis / diagnosis. Appendicitis / etiology. Appendicitis / surgery. Bone Marrow Cells / immunology. Immunosuppression. Leukemia, Myeloid, Acute / complications. Leukemia, Myeloid, Acute / drug therapy. Perioperative Care. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • [MeSH-minor] Acute Disease. Appendectomy. Child. Diagnosis, Differential. Female. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 17441480.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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56. He S, Guo Y, Bei CF, Dai YZ, Zhu DB, Li CS, Zhu XH, LE MZ: [Gastrointestinal B-cell lymphoma: a morphologic and immunohistochemical study of 194 cases]. Zhonghua Bing Li Xue Za Zhi; 2010 Dec;39(12):814-8
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  • The site of involvement included stomach (100 cases, 51.5%), small intestine (43 cases, 22.2%), ileocecal junction (26 cases, 13.4%), appendix (1 case, 0.5%), colon (21 cases, 10.8%) and rectum (3 cases, 1.6%).
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. DNA-Binding Proteins / metabolism. Female. Humans. Immunohistochemistry. Lymphoma, B-Cell, Marginal Zone / metabolism. Lymphoma, B-Cell, Marginal Zone / pathology. Lymphoma, B-Cell, Marginal Zone / surgery. Lymphoma, Follicular / metabolism. Lymphoma, Follicular / pathology. Lymphoma, Follicular / surgery. Lymphoma, Large B-Cell, Diffuse / metabolism. Lymphoma, Large B-Cell, Diffuse / pathology. Lymphoma, Large B-Cell, Diffuse / surgery. Male. Middle Aged. Neoplasm Invasiveness. Neprilysin / metabolism. Young Adult

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  • (PMID = 21215096.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / BCL6 protein, human; 0 / DNA-Binding Proteins; EC 3.4.24.11 / Neprilysin
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57. Pereira RM, Zanatta A, Preti CD, de Paula FJ, da Motta EL, Serafini PC: Should the gynecologist perform laparoscopic bowel resection to treat endometriosis? Results over 7 years in 168 patients. J Minim Invasive Gynecol; 2009 Jul-Aug;16(4):472-9
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  • Lesions were distributed as follows: 133 (79%) in the rectum, 61 (24%) in the sigmoid colon, 47 (19%) in the appendix, 5 (2%) in the terminal ileum, 3 (1%) in the descending colon, and 3 (1%) in the cecum.

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  • (PMID = 19573824.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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58. Li X, Huang J, Zhang H: An analysis of hospital preparedness capacity for public health emergency in four regions of China: Beijing, Shandong, Guangxi, and Hainan. BMC Public Health; 2008;8:319
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  • Data related to hospital demographic data; PHE preparation; response to PHE in community; stockpiles of drugs and materials; detection and identification of PHE; procedures for medical treatment; laboratory diagnosis and management; staff training; and risk communication were collected and analyzed.
  • Of the valid responses, 264 (85.2%) hospitals had emergency plans; 93.3% had command centres and personnel for PHE; 22.9% included community organisations during the training for PHE; 97.4% could transport needed medical staff to a PHE; 53.1% had evaluated stockpiles of drugs; 61.5% had evaluated their supply systems; 55.5% had developed surveillance systems; and 74.6% could monitor the abnormity(See in appendix).


59. Ziedonis DM, Smelson D, Rosenthal RN, Batki SL, Green AI, Henry RJ, Montoya I, Parks J, Weiss RD: Improving the care of individuals with schizophrenia and substance use disorders: consensus recommendations. J Psychiatr Pract; 2005 Sep;11(5):315-39
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  • Specific recommendations are provided concerning screening for substance use disorders in patients with schizophrenia, assessing motivation for change, managing medical conditions that commonly occur in patients with dual diagnoses (e.g., cardiovascular disease, liver complications, lung cancer, HIV, and hepatitis B or C infections) and selecting the most appropriate medications for such patients to maximize safety and minimize drug interactions, use of evidence-based psychosocial interventions for patients with dual diagnoses (e.g., Dual Recovery Therapy, modified cognitive-behavioral therapy, modified motivational enhancement therapy, and the Substance Abuse Management Module), and key pharmacotherapy principles for treating schizophrenia, substance use disorders, and comorbid anxiety, depression, and sleep problems in this population.
  • An algorithm summarizing the consensus recommendations is provided in an appendix.
  • [MeSH-minor] Algorithms. Antipsychotic Agents / adverse effects. Antipsychotic Agents / therapeutic use. Cognitive Therapy. Diagnosis, Dual (Psychiatry). Drug Interactions. Evidence-Based Medicine. Humans. Mental Health Services / organization & administration

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  • (PMID = 16184072.001).
  • [ISSN] 1527-4160
  • [Journal-full-title] Journal of psychiatric practice
  • [ISO-abbreviation] J Psychiatr Pract
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z99 DA999999; United States / NIDA NIH HHS / DA / K02 DA 00326
  • [Publication-type] Consensus Development Conference; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antipsychotic Agents
  • [Number-of-references] 126
  • [Other-IDs] NLM/ NIHMS81303; NLM/ PMC2599914
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60. Maghrebi H, Khalfallah M, Bedoui R, Nouira R, Sabbegh Znaïdi N, Dziri C: Endometriosis of the appendix presenting as acute appendicitis: report of a case. Gastroenterol Clin Biol; 2010 Nov;34(11):642-3
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  • [Title] Endometriosis of the appendix presenting as acute appendicitis: report of a case.
  • [MeSH-major] Appendicitis / diagnosis. Endometriosis / diagnosis
  • [MeSH-minor] Acute Disease. Adult. Appendectomy. Diagnosis, Differential. Female. Humans

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  • (PMID = 20801591.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] France
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61. Majumdar S, Prasad M, Fraser D, Roberts P: Endometriosis of the appendix presenting as acute abdomen following emergency caesarean section. J Obstet Gynaecol; 2006 Oct;26(7):692-3
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  • [Title] Endometriosis of the appendix presenting as acute abdomen following emergency caesarean section.
  • [MeSH-major] Abdomen, Acute / etiology. Appendix. Cecal Diseases / complications. Endometriosis / complications. Puerperal Disorders / etiology

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  • (PMID = 17071445.001).
  • [ISSN] 0144-3615
  • [Journal-full-title] Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
  • [ISO-abbreviation] J Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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62. Toyomasu Y, Tsutsumi S, Yamaguchi S, Mochiki E, Asao T, Kuwano H: Laparoscopy-assisted ileocecal resection for mucosa-associated lymphoid tissue lymphoma of the appendix: case report. Hepatogastroenterology; 2009 Jul-Aug;56(93):1078-81
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  • [Title] Laparoscopy-assisted ileocecal resection for mucosa-associated lymphoid tissue lymphoma of the appendix: case report.
  • A 74-year-old female had repeated relapses of right lower abdominal pain; a colonoscopic examination showed a submucosal tumor of the appendix.
  • Under provisional diagnosis of appendicitis caused by a submucosal tumor, a laparoscopic operation was performed.
  • The tumor was thought to be a malignant neoplasm.
  • The ileocecal region was excised with lymph node dissection.
  • Macroscopically, the mass was localized in the appendix and did not infiltrate to the cecum.
  • Immunohistochemically, the tumor cells were positive for CD20 and CD79a and negative for CD3, CD10, and cyclin D1.
  • The histological diagnosis was mucosa-associated lymphoid tissue (MALT) lymphoma of the appendix.
  • Furthermore, very few cases of the appendiceal MALT lymphoma have been reported.
  • The laparoscopy was used in the case of a patient diagnosed with appendicitis and considered the possibility of MALT lymphoma of the appendix.
  • We then performed an ileocecal resection, which is considered radical surgery.
  • The present case suggests that a laparoscopic observation is helpful for the appropriate diagnosis and therapy of MALT lymphoma of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / surgery. Laparoscopy. Lymphoma, B-Cell, Marginal Zone / surgery
  • [MeSH-minor] Aged. Cecum / pathology. Cecum / surgery. Colonography, Computed Tomographic. Colonoscopy. Diagnosis, Differential. Female. Humans. Ileum / pathology. Ileum / surgery. Lymph Node Excision

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  • (PMID = 19760945.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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63. Uradomo LT, Darwin PE: Evaluation of subepithelial abnormalities of the appendix by endoscopic ultrasound. Diagn Ther Endosc; 2009;2009:295379
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  • [Title] Evaluation of subepithelial abnormalities of the appendix by endoscopic ultrasound.
  • Few reports include the evaluation of the appendix by EUS.
  • Objective. To describe endoscopic and endosonographic characteristics of subepithelial lesions of the appendix.
  • Adult patients referred for evaluation of subepithelial lesions of the appendix identified by colonoscopy between April 1, 2003 to February 29, 2008.
  • Data were abstracted from an electronic endoscopic database for all patients undergoing miniprobe endoscopic ultrasound examination of the appendix.
  • Cases also included one inverted appendix, one gastrointestinal stromal tumor, and one lipoma.
  • Conclusions. EUS evaluation of the appendix is feasible with standard miniprobe devices and may assist in the selection of patients who may benefit from surgical management.

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  • (PMID = 19920863.001).
  • [ISSN] 1070-3608
  • [Journal-full-title] Diagnostic and therapeutic endoscopy
  • [ISO-abbreviation] Diagn Ther Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2777238
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64. Mavanur AA, Parimi V, O'Malley M, Nikiforova M, Bartlett DL, Davison JM: Establishment and characterization of a murine xenograft model of appendiceal mucinous adenocarcinoma. Int J Exp Pathol; 2010 Aug;91(4):357-67
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  • [Title] Establishment and characterization of a murine xenograft model of appendiceal mucinous adenocarcinoma.
  • We describe the clinical, pathologic and molecular characteristics of a xenograft model of metastatic mucinous appendiceal adenocarcinoma.
  • Tumours from patients with mucinous appendiceal neoplasms were implanted in nude mice and observed for evidence of intraperitoneal tumour growth.
  • Morphologic and immunohistochemical features, temporal growth characteristics relative to controls, and loss of heterozygosity (LOH) at multiple chromosomal alleles were assessed in a successfully engrafted tumour.
  • The successful xenograft is morphologically similar to the original tumour, produces abundant extracellular mucin and exhibits non-invasive growth on peritoneal surfaces.
  • The temporal growth characteristics of the xenograft tumour relative to controls reveal that tumour burden can be followed indirectly by measuring the weight or abdominal girth of engrafted animals.
  • The cytokeratin, mucin core protein, CDX2, Ki-67 and p53 expression patterns are identical in the xenograft and resected tumour and are consistent with the expected pattern of protein expression for mucinous adenocarcinoma of the appendix.
  • LOH was found in 1 of 10 informative chromosomal loci (chromosome 10p23) in xenograft tumour cells.
  • Although we were unable to engraft a low-grade appendiceal mucinous neoplasm, the engrafted adenocarcinoma will be useful for future evaluation of novel therapeutic strategies directed at mucinous appendiceal adenocarcinoma and evaluation of strategies for treating widespread, bulky, mucinous peritoneal surface neoplasms.
  • Xenograft tumour enrichment can facilitate molecular studies of appendiceal epithelial neoplasia.
  • [MeSH-major] Adenocarcinoma, Mucinous / secondary. Appendiceal Neoplasms / pathology. Peritoneal Neoplasms / secondary. Xenograft Model Antitumor Assays
  • [MeSH-minor] Animals. Cell Proliferation. Chromosomes, Human, Pair 10. Gene Expression Regulation, Neoplastic. Homeodomain Proteins / metabolism. Humans. Keratins / metabolism. Ki-67 Antigen / metabolism. Loss of Heterozygosity. Mice. Mice, Nude. Mucins / metabolism. Mutation. Proto-Oncogene Proteins / genetics. Time Factors. Tumor Burden. Tumor Suppressor Protein p53 / metabolism. ras Proteins / genetics

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  • (PMID = 20586814.001).
  • [ISSN] 1365-2613
  • [Journal-full-title] International journal of experimental pathology
  • [ISO-abbreviation] Int J Exp Pathol
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / T32 CA113263
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CDX2 protein, human; 0 / Homeodomain Proteins; 0 / KRAS protein, human; 0 / Ki-67 Antigen; 0 / Mucins; 0 / Proto-Oncogene Proteins; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53; 68238-35-7 / Keratins; EC 3.6.5.2 / ras Proteins
  • [Other-IDs] NLM/ PMC2962894
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65. Young A: Clinical studies. Adv Pharmacol; 2005;52:289-320
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  • The prescribers' package insert (Amylin Pharmaceuticals Inc., 2005), which includes a synopsis of safety and efficacy of pramlintide, is included as Appendix 1.

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  • (PMID = 16492555.001).
  • [ISSN] 1054-3589
  • [Journal-full-title] Advances in pharmacology (San Diego, Calif.)
  • [ISO-abbreviation] Adv. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amyloid; 0 / Hypoglycemic Agents; 0 / Islet Amyloid Polypeptide; D3FM8FA78T / pramlintide
  • [Number-of-references] 104
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66. Department of Veterans Affairs: Schedule for rating disabilities; Appendices A, B, and C. Final rule. Fed Regist; 2007 Mar 20;72(53):12983-3016
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  • Appendix A is also amended to include all the diagnostic code historical information since the last review.

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  • (PMID = 17450660.001).
  • [ISSN] 0097-6326
  • [Journal-full-title] Federal register
  • [ISO-abbreviation] Fed Regist
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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67. Deyl RT, Averbeck MA, Almeida GL, Pioner GT, Souto CA: Appendix interposition for total left ureteral reconstruction. J Pediatr Urol; 2009 Jun;5(3):237-9
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  • [Title] Appendix interposition for total left ureteral reconstruction.
  • INTRODUCTION: Appendix interposition has been described as an option for surgical reconstruction of partial and total ureteral defects both in children and adults.
  • However, to our knowledge, appendix interposition for a total left ureteral reconstruction has never been described.
  • CASE REPORT: We report the first case of total left ureteral reconstruction with cecal appendix to connect the renal pelvis of a native kidney to the urinary bladder in a 3-month-old child with ureteral necrosis following pyeloplasty.
  • CONCLUSION: Total ureteral reconstruction with cecal appendix is a feasible technique in young children.
  • Surveillance for late operative complications is required, since this is the first case of total left ureteral reconstruction with appendix to connect the renal pelvis of a native kidney to the urinary bladder.
  • [MeSH-major] Appendix / transplantation. Reconstructive Surgical Procedures / methods. Ureter / surgery. Ureteral Obstruction / surgery. Urologic Surgical Procedures, Male / methods

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  • (PMID = 19109072.001).
  • [ISSN] 1873-4898
  • [Journal-full-title] Journal of pediatric urology
  • [ISO-abbreviation] J Pediatr Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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68. Bijelic L, Yan TD, Sugarbaker PH: Treatment failure following complete cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal dissemination from colorectal or appendiceal mucinous neoplasms. J Surg Oncol; 2008 Sep 15;98(4):295-9
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  • [Title] Treatment failure following complete cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal dissemination from colorectal or appendiceal mucinous neoplasms.
  • BACKGROUND: Peritonectomy combined with perioperative intraperitoneal chemotherapy is a successful treatment option for patients with peritoneal dissemination of appendiceal and colorectal malignancy.
  • METHODS: Patients with peritoneal dissemination from appendiceal or colorectal malignancy who underwent complete cytoreduction and perioperative intraperitoneal chemotherapy were included in this study.
  • RESULTS: Seventy patients with colorectal cancer carcinomatosis and 402 with appendiceal neoplasm were analyzed.
  • The median survival of 49 patients with colorectal cancer was 33 months while the median survival for patients with appendiceal neoplasms was not reached.
  • The most common type of recurrent disease was a localized intra-abdominal recurrence for both appendiceal and colon cancer patients.
  • This resulted in 5-year survival in 17% of colorectal patients and 70% of the appendiceal mucinous neoplasm patients.
  • [MeSH-major] Adenocarcinoma, Mucinous / therapy. Appendiceal Neoplasms / pathology. Chemotherapy, Cancer, Regional Perfusion / methods. Colorectal Neoplasms / pathology. Hyperthermia, Induced. Peritoneal Neoplasms / therapy

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  • (PMID = 18726900.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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69. Onalan O, Crystal E: Left atrial appendage exclusion for stroke prevention in patients with nonrheumatic atrial fibrillation. Stroke; 2007 Feb;38(2 Suppl):624-30
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  • The left atrial appendix (LAA) is the most common place of thrombosis in patients with AF, and it can easily be excluded from the systemic circulation at the time of cardiac surgery by excision, ligation, suturing, or stapling.


70. Djuranovic SP, Spuran MM, Kovacevic NV, Ugljesic MB, Kecmanovic DM, Micev MT: Mucinous cystadenoma of the appendix associated with adenocarcinoma of the sigmoid colon and hepatocellular carcinoma of the liver: report of a case. World J Gastroenterol; 2006 Mar 28;12(12):1975-7
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  • [Title] Mucinous cystadenoma of the appendix associated with adenocarcinoma of the sigmoid colon and hepatocellular carcinoma of the liver: report of a case.
  • Mucinous cystadenoma of the appendix is a rare condition and represents one of the three entities with the common name mucocele of the appendix.
  • This condition is often associated with other neoplasia, especially adenocarcinoma of the colon and ovaries.
  • He had a big cystadenoma of the appendix associated with adenocarcinoma of the colon and hepatocellular carcinoma of the liver.
  • According to this, we stress the need of accurate preoperative diagnosis and intraoperative exploration of the whole abdomen in these patients.
  • [MeSH-major] Adenocarcinoma / complications. Appendiceal Neoplasms / complications. Carcinoma, Hepatocellular / complications. Cystadenoma, Mucinous / complications. Liver Neoplasms / complications. Sigmoid Neoplasms / complications

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  • [Cites] Dis Colon Rectum. 2000 Apr;43(4):559-60 [10789759.001]
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  • (PMID = 16610012.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4087531
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71. Warburg MR: Reproductive system of female scorpion: a partial review. Anat Rec (Hoboken); 2010 Oct;293(10):1738-54
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  • This type is found in a few scorpion species. (2) The katoikogenic type with an ovariuterus where the embryo develops in a diverticulum composed of four parts: a stalk (pedicel), a thickened collar, a conical portion containing the ovum, and an appendix containing the oral feeding apparatus where the embryos' chelicerae grip a "teat"-like structure, described in four families: Hemiscorpiidae, Scorpionidae, Urodacidae, and Diplocentridae.

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  • [Copyright] Copyright © 2010 Wiley-Liss, Inc.
  • (PMID = 20687160.001).
  • [ISSN] 1932-8494
  • [Journal-full-title] Anatomical record (Hoboken, N.J. : 2007)
  • [ISO-abbreviation] Anat Rec (Hoboken)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Yoon WJ, Yoon YB, Kim YJ, Ryu JK, Kim YT: Metastasis to the gallbladder: a single-center experience of 20 cases in South Korea. World J Gastroenterol; 2009 Oct 14;15(38):4806-9
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  • The primary malignancies originated from the stomach (n = 8), colorectum (n = 3), liver (n = 2), kidney (n = 2), skin (n = 2), extrahepatic bile duct (n = 1), uterine cervix (n = 1), and appendix (n = 1).
  • The median survival after the diagnosis of MGB was 8.7 mo.
  • [MeSH-minor] Abdominal Pain / diagnosis. Adult. Aged. CA-19-9 Antigen / biosynthesis. Cholecystitis / diagnosis. Female. Humans. Jaundice / diagnosis. Male. Middle Aged. Neoplasm Metastasis. Proportional Hazards Models. Republic of Korea. Retrospective Studies. Weight Loss / drug effects

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  • [Cites] Am Surg. 2007 Aug;73(8):833-5 [17879698.001]
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  • (PMID = 19824115.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / CA-19-9 Antigen
  • [Other-IDs] NLM/ PMC2761559
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73. Butrón Valdez K, Ramírez Galves M, Germes Piña F, Ramos Martínez E, Zamora Perea A: [Systemic lymphoma cells with T precursor condition of extreme female genital tract. A case report and literature review]. Ginecol Obstet Mex; 2009 Jun;77(6):291-9
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  • [Transliterated title] Linfoma linfoblástico sistémico de células precursoras T con afección extrema del aparato genital femenino. Reporte de un caso y revisión de la bibliografía.
  • Primary female genital tract non Hodgkin's lymphoma is a rare presentation for a common disease in the childhood, and its classification as primary extranodal lymphoma is still controversial.
  • There are a few cases reported as a primary precursor B-cell lymphoblastic lymphoma of the female genital tract, but there is not any case reported as primary precursor T-cell lymphoblastic lymphoma of the ovary in childhood.
  • Herein we describe a 16 years old young woman with bilateral ovarian tumors, paraaortic lymphoadenophaty and disseminate disease to the female genital tract including extension of the tumor to neighboring organs like the omentum and the appendix.
  • The chemotherapy regimen comprised of CHOP (Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone/Prednisolone) and methotrexate, 3 months later presents left facial hemiparesia follow by right facial hemiparesia, 7 months later presents more Central Nervous System (CNS) complications and apparently was complicated with acute lymphocitic leukemia and after 16 months from the diagnosis, following by a torpid evolution, the pacient finally died.

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  • (PMID = 19681371.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Mexico
  • [Number-of-references] 19
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74. Mizuta Y, Akazawa Y, Shiozawa K, Ohara H, Ohba K, Ohnita K, Isomoto H, Takeshima F, Omagari K, Tanaka K, Yasutake T, Nakagoe T, Shirono K, Kohno S: Pseudomyxoma peritonei accompanied by intraductal papillary mucinous neoplasm of the pancreas. Pancreatology; 2005;5(4-5):470-4
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  • [Title] Pseudomyxoma peritonei accompanied by intraductal papillary mucinous neoplasm of the pancreas.
  • This case is unique due to the concurrent presence of intraductal papillary mucinous neoplasm (IPMN) of the pancreas.
  • No primary tumour, including mucinous neoplasm of the appendix, was found.
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Ascites / pathology. Chemotherapy, Cancer, Regional Perfusion. Cisplatin / administration & dosage. Deoxycytidine / analogs & derivatives. Etoposide / administration & dosage. Humans. Hyperthermia, Induced. Infusions, Parenteral. Male. Middle Aged. Mitomycin / administration & dosage. Neoplasms, Multiple Primary

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  • [Copyright] Copyright 2005 S. Karger AG, Basel and IAP.
  • (PMID = 15983445.001).
  • [ISSN] 1424-3903
  • [Journal-full-title] Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
  • [ISO-abbreviation] Pancreatology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; 50SG953SK6 / Mitomycin; 6PLQ3CP4P3 / Etoposide; B76N6SBZ8R / gemcitabine; Q20Q21Q62J / Cisplatin
  • [Number-of-references] 19
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75. Nandipati K, Parithivel V, Niazi M: Schistosomiasis: a rare cause of acute appendicitis in the African American population in the United States. Am Surg; 2008 Mar;74(3):221-3
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  • All patients underwent appendectomy and each was found to have an enlarged and inflamed appendix intraoperatively.
  • Schistosomal granulations are present in all layers of appendix including serosa.


76. Cissé M, Touré AO, Konaté I, Dieng M, Ka O, Touré FB, Dia A, Touré CT: Appendicular peritonitis in situs inversus totalis: a case report. J Med Case Rep; 2010;4:134
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  • We discovered a situs inversus at the left side of his liver, and his appendix was perforated in its middle third.

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  • [Cites] J Am Coll Surg. 2008 Dec;207(6):954 [19183546.001]
  • [Cites] Arch Pediatr. 1996 Jan;3(1):47-50 [8745827.001]
  • (PMID = 20459847.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2876173
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77. vanSonnenberg E, Goodacre BW, Wittich GR, Ali S, Silverman SG, Shankar S, Tuncali K: Interventional radiology strategies in the treatment of pseudomyxoma peritonei. Cardiovasc Intervent Radiol; 2005 Jul-Aug;28(4):490-4
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  • The causes of the PMP were tumors in the ovary (2 patients), appendix (1 patient), and colon (1 patient).

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  • (PMID = 16034657.001).
  • [ISSN] 0174-1551
  • [Journal-full-title] Cardiovascular and interventional radiology
  • [ISO-abbreviation] Cardiovasc Intervent Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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78. Vasei M, Zakeri Z, Azarpira N, Hosseini SV, Solaymani-Dodaran M: Serotonin content of normal and inflamed appendix: a possible role of serotonin in acute appendicitis. APMIS; 2008 Nov;116(11):947-52
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  • [Title] Serotonin content of normal and inflamed appendix: a possible role of serotonin in acute appendicitis.
  • The appendix is lined by a mucosa which has many neuroendocrine cells containing serotonin.
  • In this study we explored the serotonin content of the neuroendocrine cells of the appendixes removed for clinical diagnosis of appendicitis.
  • Appendix specimens were divided into three groups: Acute appendicitis (AA), non-appendicitis (NA), and follicular hyperplasia (FH).
  • Normal appendix specimens from patients undergoing elective abdominal surgery were used as the control group (NL).
  • The inflamed appendix is markedly depleted of serotonin in the epithelium and lamina propria.
  • Local serotonin release from ECs and SNCs in the appendix may act as an inflammatory mediator in appendicitis and is likely to be the source of raised blood serotonin in AA.
  • [MeSH-major] Appendicitis / metabolism. Appendix / metabolism. Enterochromaffin Cells / metabolism. Neuroendocrine Cells / metabolism. Serotonin / metabolism

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  • (PMID = 19132991.001).
  • [ISSN] 1600-0463
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Chromogranin A; 0 / Synaptophysin; 333DO1RDJY / Serotonin
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79. Hu CC, Chang JJ, Chen TC, Yen CL, Chien RN: Colonoscopic feature of primary adenocarcinoma of the appendix:. Intern Med; 2008;47(4):255-7
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  • [Title] Colonoscopic feature of primary adenocarcinoma of the appendix:.
  • We herein report a case of primary adenocarcinoma of the appendix, a very rare disease that is seldom diagnosed before surgical intervention.
  • This case was first suspected for its unique colonoscopic presentation as a cecal submucosal tumor with an overlying mucin-coat at the appendiceal orifice.
  • The diagnosis was later confirmed after the operation.
  • [MeSH-major] Adenocarcinoma / pathology. Appendix. Cecal Neoplasms / pathology. Colonoscopy

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  • (PMID = 18277025.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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80. Yajima N, Wada R, Yamagishi S, Mizukami H, Itabashi C, Yagihashi S: Immunohistochemical expressions of cytokeratins, mucin core proteins, p53, and neuroendocrine cell markers in epithelial neoplasm of appendix. Hum Pathol; 2005 Nov;36(11):1217-25
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  • [Title] Immunohistochemical expressions of cytokeratins, mucin core proteins, p53, and neuroendocrine cell markers in epithelial neoplasm of appendix.
  • Epithelial neoplasms of appendix are infrequent, and their pathological features are not fully characterized.
  • We collected 33 cases of appendiceal tumors and examined immunohistochemically the expression of cytokeratins (CK, CK7, and CK20), mucin core protein (MUC1, MUC2, MUC5AC, and MUC6), E-cadherin, chromogranin A, and p53 protein.
  • Although chromogranin A-positive cells are generally sparse in normal appendix, they were more common in mucinous tumors than in nonmucinous tumors.
  • This is the first report that characterized the immunophenotypic profile of appendiceal epithelial neoplasms with an emphasis of a higher frequency of p53 positivity in mucinous carcinoma cases compared with mucinous adenoma in the appendix.
  • [MeSH-major] Appendiceal Neoplasms / metabolism. Biomarkers, Tumor / analysis. Keratins / biosynthesis. Mucins / biosynthesis. Neoplasms, Glandular and Epithelial / metabolism. Tumor Suppressor Protein p53 / biosynthesis


81. Umer MA, Date RS, Mellor S, Nair B, Ward JB: Hodgkin's disease of appendix: report of a case. Colorectal Dis; 2009 Nov;11(9):985-7
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  • [Title] Hodgkin's disease of appendix: report of a case.
  • BACKGROUND: A number of cases of non Hodgkin's lymphoma of the appendix have been described, but Hodgkin's lymphoma is extremely rare.
  • The resected segment of bowel demonstrated classical Hodgkin's disease originating in the appendix.
  • CONCLUSION: Hodgkin's lymphoma of appendix is extremely rare.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Hodgkin Disease / pathology
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bleomycin / therapeutic use. Dacarbazine / therapeutic use. Doxorubicin / therapeutic use. Humans. Male. Neoplasm Staging. Vinblastine / therapeutic use

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  • (PMID = 19175635.001).
  • [ISSN] 1463-1318
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 5V9KLZ54CY / Vinblastine; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; ABVD protocol
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82. Pulvirenti E, Toro A, Di Carlo I: Giant appendix as result of chronic appendicitis: report of a case. Acta Gastroenterol Belg; 2010 Jul-Sep;73(3):409-10
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  • [Title] Giant appendix as result of chronic appendicitis: report of a case.
  • [MeSH-major] Appendicitis / pathology. Appendix / pathology

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  • (PMID = 21086950.001).
  • [ISSN] 1784-3227
  • [Journal-full-title] Acta gastro-enterologica Belgica
  • [ISO-abbreviation] Acta Gastroenterol. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Belgium
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83. Hadi HI, Quah HM, Maw A: A missing tongue stud: an unusual appendicular foreign body. Int Surg; 2006 Mar-Apr;91(2):87-9
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  • Previous reports have described a variety of foreign bodies that were either found incidentally in the appendix or were felt to be responsible for appendicitis.
  • The missing "tongue stud" had impacted in the appendix and was successfully removed by laparoscopic appendicectomy with resolution of patient's symptoms.
  • We review the literature covering the clinical management of patients presenting with foreign bodies in the appendix.
  • [MeSH-major] Appendix. Body Piercing / instrumentation. Foreign Bodies / diagnosis. Tongue

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  • (PMID = 16774178.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 8
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84. Kiratli PO, Aksoy T, Bozkurt MF, Orhan D: Detection of ectopic gastric mucosa using 99mTc pertechnetate: review of the literature. Ann Nucl Med; 2009 Feb;23(2):97-105
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  • Three patients showed atypical findings on scintigraphy which were perforated appendix, calyceal stasis, and regional enteritis.

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  • (PMID = 19225931.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; A0730CX801 / Sodium Pertechnetate Tc 99m
  • [Number-of-references] 25
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86. Harris WF: Flipped optical systems. Ophthalmic Physiol Opt; 2008 Nov;28(6):595-602
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  • Three numerical examples are given in the Appendix.

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  • (PMID = 19076562.001).
  • [ISSN] 1475-1313
  • [Journal-full-title] Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
  • [ISO-abbreviation] Ophthalmic Physiol Opt
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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87. Ohtani O, Ohtani Y: Organization and developmental aspects of lymphatic vessels. Arch Histol Cytol; 2008 May;71(1):1-22
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  • The lymphatic system is involved in many pathological conditions, including lymphedema, inflammatory diseases, and tumor dissemination.
  • Therefore, the present paper reviews the organization of the lymphatic vascular system of a variety of organs, including the thyroid gland, lung and pleura, small intestine, cecum and colon in the rat, the diaphragm in the rat, monkey, and human, Peyer's patches and the appendix in the rabbit, and human tonsils.

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  • (PMID = 18622090.001).
  • [ISSN] 0914-9465
  • [Journal-full-title] Archives of histology and cytology
  • [ISO-abbreviation] Arch. Histol. Cytol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Japan
  • [Number-of-references] 120
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88. Brankov O, Dumanov K, Stoilov S, Doĭnova P, Drebov R, Khristozova I: [Non-Hodgkin's primary intestinal lymphoma - a cause of acute abdominal manifestation in children]. Khirurgiia (Sofiia); 2007;(4):10-3
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  • [Title] [Non-Hodgkin's primary intestinal lymphoma - a cause of acute abdominal manifestation in children].
  • AIM: Lymphomas of the gastrointestinal tract are the most common type of primary extranodal lymphomas, accounting for 5 to 10% of all non-Hodgkin's lymphomas (NHL).
  • PATIENTS AND METHODS: From January 1996 to November 2005, 10 patients with primary intestinal lymphomas were submitted with clinical signs of acute abdomen to the Pediatric surgical department in Sofia.
  • RESULTS: At exploration the tumor was located in the ileum in 4 cases, in the terminal ileum and coecum in 3 cases, appendix in one and multiple sites were found in 2 cases.
  • Children with localized disease underwent radical resection of the tumor mass with ileo - transverso anastomosis (3), partial bowel resection (4), and appendectomy (1) whereas in 2 children with advanced disease diagnostic biopsy alone with temporary ileostomy in one were accomplished.
  • CONCLUSION: Primary NHL in children often presents with acute abdominal condition requiring surgical exploration.

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  • (PMID = 18443528.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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89. Arnold R, McCallion K, McGailie C: Goblet cell carcinoids of the appendix. Ulster Med J; 2006 Jan;75(1):40-5
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  • [Title] Goblet cell carcinoids of the appendix.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Carcinoid Tumor / diagnosis
  • [MeSH-minor] Abdominal Pain / etiology. Adult. Appendicitis / diagnosis. Appendicitis / surgery. Humans. Male. Nausea / etiology. Vomiting / etiology

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  • [Cites] Cancer. 2003 Feb 15;97(4):934-59 [12569593.001]
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  • (PMID = 16457403.001).
  • [ISSN] 0041-6193
  • [Journal-full-title] The Ulster medical journal
  • [ISO-abbreviation] Ulster Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Northern Ireland
  • [Number-of-references] 13
  • [Other-IDs] NLM/ PMC1891799
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90. Lukish J, Powell D, Morrow S, Cruess D, Guzzetta P: Laparoscopic appendectomy in children: use of the endoloop vs the endostapler. Arch Surg; 2007 Jan;142(1):58-61; discussion 62
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  • HYPOTHESIS: Two techniques are used for laparoscopic appendectomy (LA): division of the mesoappendix with the harmonic scalpel and ligation of the appendix with an endoloop (EL), or division of the mesoappendix and appendix with an endostapler (ES).
  • MAIN OUTCOME MEASURES: Age, diagnosis, length of stay, surgical time, total operating room time, complications, and instrumentation costs were compared between the EL and ES groups.

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  • (PMID = 17224501.001).
  • [ISSN] 0004-0010
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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91. Legnani GL, Rasini M, Pastori S, Sarli D: Laparoscopic trans-peritoneal hernioplasty (TAPP) for the acute management of strangulated inguino-crural hernias: a report of nine cases. Hernia; 2008 Apr;12(2):185-8
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  • Both have a definite role in the treatment of bilateral and recurrent hernias, while the debate is still open about the treatment of primary mono-lateral hernias.
  • RESULTS: One case was associated with intestinal resection and incisional hernia repair, one with obturator hernia repair, and one with hepiployc appendix repair.

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  • (PMID = 18004500.001).
  • [ISSN] 1265-4906
  • [Journal-full-title] Hernia : the journal of hernias and abdominal wall surgery
  • [ISO-abbreviation] Hernia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
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92. Bouvard M, Cosma P: [An exploratory study of a personality disorders questionnaire]. Encephale; 2008 Oct;34(5):517-25
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  • [Transliterated title] Etude exploratoire d'un questionnaire sur les troubles de la personnalité
  • New York: New York State Psychiatric Institute; 1994] Personality Diagnostics Questionnaire (PDQ-4 plus) with an investigation into whether Eysenck's personality dimensions allow us to differentiate between subjects diagnosed by the PDQ-4 plus as showing at least one personality disorder (PD) and control subjects.
  • PARTICIPANTS: A group of 129 French undergraduate students completed the PDQ-4 plus, a self-report questionnaire designed to assess the 12 PDs of the DSM-IV (10 PDs and two additional diagnoses included in the appendix of the DSM-IV), and, at the same time, the Eysenck Personality Questionnaire Revised-Abbreviated (EPQ RA).
  • In the population as a whole, studies have shown the prevalence of any DSM-IV defined personality disorder to be between 9 and 15%; however, personality disorders are much more frequently diagnosed in younger subjects (Ekselius L., Tillfors M., Furmark T., & Fredrikson M.
  • [MeSH-major] Personality Disorders / diagnosis. Personality Inventory / statistics & numerical data

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  • (PMID = 19068342.001).
  • [ISSN] 0013-7006
  • [Journal-full-title] L'Encéphale
  • [ISO-abbreviation] Encephale
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] France
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93. Nikou GC, Lygidakis NJ, Toubanakis C, Pavlatos S, Tseleni-Balafouta S, Giannatou E, Mallas E, Safioleas M: Current diagnosis and treatment of gastrointestinal carcinoids in a series of 101 patients: the significance of serum chromogranin-A, somatostatin receptor scintigraphy and somatostatin analogues. Hepatogastroenterology; 2005 May-Jun;52(63):731-41
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  • [Title] Current diagnosis and treatment of gastrointestinal carcinoids in a series of 101 patients: the significance of serum chromogranin-A, somatostatin receptor scintigraphy and somatostatin analogues.
  • The primary tumors originated from the GI tract in 97/101 pts (appendix 34%, small intestine 31%, stomach 14%, duodenum 6%, colon 6%, rectum 3%) and from the pancreas in 4/101 (4%).
  • The diagnosis was confirmed histologically in all cases, after surgical excision of the primary tumor or by biopsies taken during endoscopy.
  • RESULTS: Patients were referred to us with gastrointestinal symptoms or symptoms of the "carcinoid syndrome" (flushing, and diarrhea), depending mainly on the location of the primary tumors and the existence or not of metastases.
  • Localization of the primary tumors to facilitate surgery was made by many imaging techniques (US, CT, MRI, Enteroclysis, OCTREOSCAN) and endoscopic procedures.
  • Furthermore, it revealed the primary and the metastatic lesions in 16% and 33% of pts with carcinoids of the small intestine respectively, while other conventional imaging procedures (including MRI) were negative at the same time.
  • Seventy-four percent of the pts underwent a surgical resection of the primary tumor, while in 21%, an endoscopic polypectomy was performed.
  • All pts with metastatic tumors and positive OCTREOSCAN, were treated with Somatostatin analogues, which resulted in control of symptoms (75%), stabilization of tumor growth (71%) or tumor shrinkage (9%).
  • CONCLUSIONS: a) Tumor size (especially in appendiceal and gastric carcinoids) and, also, the dispersion of disease, highly predict the evolution of the patients;.
  • b) serum Chromogranin-A seems to be a very useful tumor marker for the diagnosis and follow-up of pts with GI carcinoids;.
  • c) the introduction of new imaging techniques and especially OCTREOSCAN contributes to a better localization of the primary tumors and their metastases, as well as, to the right decision of the appropriate medical treatment;.
  • [MeSH-major] Biomarkers, Tumor / blood. Carcinoid Tumor / diagnosis. Chromogranins / blood. Gastrointestinal Neoplasms / diagnosis. Receptors, Somatostatin / blood. Somatostatin / analogs & derivatives

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  • (PMID = 15966194.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CHGA protein, human; 0 / Chromogranin A; 0 / Chromogranins; 0 / Receptors, Somatostatin; 51110-01-1 / Somatostatin; 54-16-0 / Hydroxyindoleacetic Acid; G083B71P98 / pentetreotide
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94. Ibelings BW, Havens KE: Cyanobacterial toxins: a qualitative meta-analysis of concentrations, dosage and effects in freshwater, estuarine and marine biota. Adv Exp Med Biol; 2008;619:675-732
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  • The meta-analysis is set up by putting together two large tables--embodying a large and representative part of the literature (see Appendix A).

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  • (PMID = 18461789.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bacterial Toxins; 0 / Marine Toxins; 0 / Microcystins; 0 / cyanobacterial toxin
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95. Vaida F, Liu L: Fast Implementation for Normal Mixed Effects Models With Censored Response. J Comput Graph Stat; 2009;18(4):797-817
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  • The proposed algorithm is implemented in the R package lmec.
  • An appendix which includes further mathematical details, the R code, and datasets for examples and simulations are available as the online supplements.

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  • (PMID = 25829836.001).
  • [ISSN] 1061-8600
  • [Journal-full-title] Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America
  • [ISO-abbreviation] J Comput Graph Stat
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / U01 AI043638; United States / NIMH NIH HHS / MH / N01MH22005; United States / NIMH NIH HHS / MH / P30 MH062512; United States / NIAID NIH HHS / AI / R01 AI047033; United States / NIAID NIH HHS / AI / P01 AI074621
  • [Publication-type] JOURNAL ARTICLE
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Detection limit / EM algorithm / HIV viral load / Maximum likelihood / Truncated multinormal distribution
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96. Sugarbaker PH: Laboratory and clinical basis for hyperthermia as a component of intracavitary chemotherapy. Int J Hyperthermia; 2007 Aug;23(5):431-42
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  • Intraoperative chemotherapy with heat has been identified as a treatment option for patients with cancer spread to peritoneal surfaces.
  • The pharmacologic basis for using heat to supplement chemotherapy effects are related to the increased penetration of chemotherapy into tumor with hyperthermia, the delayed clearance of chemotherapy from the peritoneal cavity after direct instillation, and an increased cytotoxicity that has been documented with selected chemotherapy agents.
  • Data to support the use of perioperative hyperthermic intraperitoneal chemotherapy with mucinous appendiceal carcinomatosis comes from a large number of single institution phase II studies.
  • In colon cancer carcinomatosis, large phase II multi-institutional trials and a single phase III trial documented an increased median survival of these patients from approximately 1 year to over 2 years.
  • Prophylaxis against peritoneal carcinomatosis in gastric cancer has been demonstrated in phase III trials.
  • In ovarian cancer the rationale for this treatment remains large but its current application is limited.

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  • (PMID = 17701534.001).
  • [ISSN] 0265-6736
  • [Journal-full-title] International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • [ISO-abbreviation] Int J Hyperthermia
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 80168379AG / Doxorubicin
  • [Number-of-references] 53
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97. Carta MG, Bernal M, Hardoy MC, Haro-Abad JM, Report on the Mental Health in Europe Working Group: Migration and mental health in Europe (the state of the mental health in Europe working group: appendix 1). Clin Pract Epidemiol Ment Health; 2005 Aug 31;1:13
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  • [Title] Migration and mental health in Europe (the state of the mental health in Europe working group: appendix 1).

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  • (PMID = 16135246.001).
  • [ISSN] 1745-0179
  • [Journal-full-title] Clinical practice and epidemiology in mental health : CP & EMH
  • [ISO-abbreviation] Clin Pract Epidemiol Ment Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1236945
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98. Selected suppliers of reagents and equipment. Curr Protoc Mol Biol; 2008 Jan;Appendix 4:Appendix 4
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  • This appendix lists the full contact information, including website URLs, for all suppliers mentioned in Current Protocols in Molecular Biology.

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  • (PMID = 18231978.001).
  • [ISSN] 1934-3647
  • [Journal-full-title] Current protocols in molecular biology
  • [ISO-abbreviation] Curr Protoc Mol Biol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Indicators and Reagents
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99. Pai RK, Beck AH, Norton JA, Longacre TA: Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence. Am J Surg Pathol; 2009 Oct;33(10):1425-39
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence.
  • The classification and nomenclature of appendiceal mucinous neoplasms are controversial.
  • To determine the outcome for patients with appendiceal mucinous neoplasms and further evaluate whether they can be stratified into groups that provide prognostic information, the clinicopathologic features of 116 patients (66 with clinical follow-up) with appendiceal mucinous neoplasms were studied.
  • From a wide variety of histopathologic features assessed, the important predictors that emerged on univariate statistical analysis were presence of extra-appendiceal neoplastic epithelium (P=0.01), high-grade cytology (P<0.0001), architectural complexity (P<0.001), and invasion (P<0.001).
  • All 16 patients with mucinous neoplasms confined to the appendix and lacking high-grade cytology, architectural complexity, and invasion were alive with no recurrences at median 59 months follow-up (=mucinous adenoma).
  • One of 14 patients with low-grade cytology and acellular peritoneal mucin deposits developed recurrent tumor within the peritoneum at 45 months with no patient deaths to date (median, 48-mo follow-up) (=low-grade mucinous neoplasm with low risk of recurrence).
  • Twenty-seven patients with low-grade mucinous neoplasms with extra-appendiceal neoplastic epithelium had 1-year, 3-year, 5-year, and 10-year overall survival rates of 96%, 91%, 79%, and 46%, respectively, at median 53 months follow-up (=low-grade mucinous neoplasm with high risk of recurrence).
  • Three of the 4 patients with extra-appendiceal epithelium limited to the right lower quadrant developed full-blown peritoneal disease at 6, 41, and 99 months follow-up and 1 patient eventually died of disease.
  • Nine patients with appendiceal neoplasms with invasion or high-grade cytology and follow-up showed 1-year, 3-year, and 5-year overall survival rates of 86%, 57%, and 28% (=mucinous adenocarcinoma).
  • Appendiceal mucinous neoplasms can be stratified into 4 distinct risk groups on the basis of a careful histopathologic assessment of cytoarchitectural features and extent of disease at presentation.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Appendiceal Neoplasms / pathology. Neoplasm Recurrence, Local / epidemiology

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  • (PMID = 19641451.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NLM NIH HHS / LM / T15 LM007033
  • [Publication-type] Journal Article
  • [Publication-country] United States
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100. Petroianu A, Alberti LR, Zac RI: [Importance of the radiographic sign of fecal loading in the cecum for the differential diagnosis of acute appendicitis]. Acta Med Port; 2007 Mar-Apr;20(2):151-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Importance of the radiographic sign of fecal loading in the cecum for the differential diagnosis of acute appendicitis].
  • [Transliterated title] Importância do sinal radiográfico de acúmulo fecal no ceco para o diagnóstico diferencial de apendicite aguda.
  • The image usually disappears soon after the appendix is removed.
  • When a diagnosis of acute appendicitis is suspected, the absence of this sign indicates great possibility of a different diagnosis.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Infant. Infant, Newborn. Male. Middle Aged. Prospective Studies

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  • (PMID = 17868521.001).
  • [ISSN] 1646-0758
  • [Journal-full-title] Acta médica portuguesa
  • [ISO-abbreviation] Acta Med Port
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Portugal
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