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Items 1 to 68 of about 68
1. MacNeill KN, Riddell RH, Ghazarian D: Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature. J Clin Pathol; 2005 Feb;58(2):217-9
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for apocrine adenoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature.
  • Benign apocrine lesions have been described in the anogenital region, although according to the World Health Organisation convincing examples of anal apocrine adenocarcinomas have not been published.
  • This report describes the case of an invasive apocrine adenocarcinoma arising in a benign adenoma in the perianal region of a 45 year old woman.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Sweat Gland / pathology. Anus Neoplasms / pathology. Apocrine Glands / pathology. Sweat Gland Neoplasms / pathology

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  • The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for apocrine adenocarcinoma .
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  • (PMID = 15677547.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 12
  • [Other-IDs] NLM/ PMC1770559
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2. Fernandez-Flores A: The elusive differential diagnosis of cutaneous apocrine adenocarcinoma vs. metastasis: the current role of clinical correlation. Acta Dermatovenerol Alp Pannonica Adriat; 2009 Sep;18(3):141-2
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  • [Title] The elusive differential diagnosis of cutaneous apocrine adenocarcinoma vs. metastasis: the current role of clinical correlation.
  • [MeSH-major] Adenocarcinoma / diagnosis. Apocrine Glands / pathology. Breast Neoplasms / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / secondary. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans

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  • (PMID = 19784530.001).
  • [ISSN] 1318-4458
  • [Journal-full-title] Acta dermatovenerologica Alpina, Pannonica, et Adriatica
  • [ISO-abbreviation] Acta Dermatovenerol Alp Pannonica Adriat
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] Slovenia
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3. Alex G: Apocrine adenocarcinoma of the nipple: a case report. Cases J; 2008;1(1):88

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apocrine adenocarcinoma of the nipple: a case report.
  • Apocrine adenocarcinomas are rare malignant skin adnexal tumours.
  • Apocrine carcinoma of the nipple is extremely rare and this case to the author's knowledge is only the third reported case worldwide and the first with associated ductal carcinoma in situ elsewhere in the breast.
  • A seventy one year old caucasian female presented to the breast clinic with a growth on her nipple which proved on histopathological analysis to be an apocrine carcinoma.
  • Recommended treatment for apocrine carcinoma includes surgery in the form of wide local excision.

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  • (PMID = 18700029.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2526981
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4. Cohen M, Cassarino DS, Shih HB, Abemayor E, St John M: Apocrine hidradenocarcinoma of the scalp: a classification conundrum. Head Neck Pathol; 2009 Mar;3(1):42-6
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  • [Title] Apocrine hidradenocarcinoma of the scalp: a classification conundrum.
  • Traditionally, cutaneous sweat gland tumors have been classified by either eccrine or apocrine features.
  • RESULTS: Final pathology revealed an apocrine hidradenocarcinoma.
  • CONCLUSION: Apocrine hidradenocarcinoma can be viewed as an aggressive malignant lesion of cutaneous sweat glands on a spectrum that involves both eccrine and apoeccrine lesions.
  • [MeSH-major] Adenocarcinoma / classification. Apocrine Glands / pathology. Head and Neck Neoplasms / classification. Scalp / pathology. Sweat Gland Neoplasms / classification

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  • (PMID = 20596988.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807530
  • [Keywords] NOTNLM ; Apocrine / Eccrine / Head / Hidradenocarcinoma / Neck / Scalp / Sweat gland
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5. Miwa Y, Mochiduki M, Nakayama H, Shibuya N, Ogawa H, Sasaki N: Apocrine adenocarcinoma of possible sweat gland origin in a male rabbit. J Small Anim Pract; 2006 Sep;47(9):541-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apocrine adenocarcinoma of possible sweat gland origin in a male rabbit.
  • The histopathological diagnosis of the mass was apocrine adenocarcinoma.
  • To the authors' knowledge, this report describes the first case of spontaneous apocrine adenocarcinoma of possible sweat gland origin in a male rabbit.
  • [MeSH-major] Adenocarcinoma / veterinary. Apocrine Glands / pathology. Rabbits. Sweat Gland Neoplasms / veterinary

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  • (PMID = 16961473.001).
  • [ISSN] 0022-4510
  • [Journal-full-title] The Journal of small animal practice
  • [ISO-abbreviation] J Small Anim Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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6. Miyamoto T, Hagari Y, Inoue S, Watanabe T, Yoshino T: Axillary apocrine carcinoma with benign apocrine tumours: a case report involving a pathological and immunohistochemical study and review of the literature. J Clin Pathol; 2005 Jul;58(7):757-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Axillary apocrine carcinoma with benign apocrine tumours: a case report involving a pathological and immunohistochemical study and review of the literature.
  • BACKGROUND: Apocrine carcinoma is rare and often occurs in the axilla.
  • This is the second apocrine carcinoma arising in bilateral axillae with associated apocrine hyperplasia to be reported.
  • AIMS/METHODS: Because benign apocrine tumours may be precursors of cancer, this case was investigated immunohistochemically and histologically, and a literature (English and Japanese) review undertaken of cases with coexistent malignant and benign apocrine tumours in the axilla to elucidate the relation between apocrine carcinoma and benign apocrine tumours.
  • RESULTS: Only four cases of axillary apocrine carcinoma with benign apocrine tumours were identified in the literature.
  • In each case, benign apocrine hyperplasia was situated within and surrounding the adenocarcinomatous nests.
  • (2) combined luminal surface and cytoplasmic staining of glandular cells; and (3) a strongly positive lineal staining pattern at the luminal membrane surface, comprising one or two apocrine hyperplastic secretory cells.
  • The basal lesions of apocrine hyperplasia were strongly positive for alpha smooth muscle actin, whereas the periphery of adenomatous lesions showed weaker positive staining, even though the periphery of adenocarcinomatous lesions was negative.
  • CONCLUSIONS: All five apocrine carcinomas with benign apocrine tumours occurred in elderly Japanese men who had bilateral benign apocrine tumours even if affected by unilateral axillary apocrine carcinoma.
  • The immunohistochemical results support the notion that apocrine hyperplasia is a precursor of cancer and that apocrine carcinoma, adenoma, and hyperplasia may be successive steps in the linear progression to carcinoma.
  • [MeSH-major] Adenocarcinoma, Papillary / pathology. Apocrine Glands / pathology. Precancerous Conditions / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 15976347.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 18
  • [Other-IDs] NLM/ PMC1770727
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7. Pakhrin B, Kang MS, Bae IH, Park MS, Jee H, You MH, Kim JH, Yoon BI, Choi YK, Kim DY: Retrospective study of canine cutaneous tumors in Korea. J Vet Sci; 2007 Sep;8(3):229-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The top ten most frequently diagnosed cutaneous tumors were epidermal and follicular cysts (12.70%), lipoma (11.36%), mast cell tumors (8.82%), cutaneous histiocytoma (7.49%), basal cell tumors (6.82%), sebaceous gland adenoma (6.68%), sebaceous gland hyperplasia (5.08%), hepatoid gland adenoma (3.61%), apocrine adenocarcinoma (3.07%), and fibroma (2.81%), in order of prevalence.

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  • (PMID = 17679768.001).
  • [ISSN] 1229-845X
  • [Journal-full-title] Journal of veterinary science
  • [ISO-abbreviation] J. Vet. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2868128
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8. Lozano M, Gonzalez F: [Adenocarcinoma with apocrine differentiation of the lacrimal gland]. Arch Soc Esp Oftalmol; 2007 Apr;82(4):229-31
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  • [Title] [Adenocarcinoma with apocrine differentiation of the lacrimal gland].
  • [Transliterated title] Adenocarcinoma con diferenciación apocrina de la glándula lagrimal.
  • The histopathologic study showed a tumor consistent with an adenocarcinoma of the lacrimal gland with apocrine differentiation.
  • [MeSH-major] Adenocarcinoma / pathology. Eye Diseases / pathology. Lacrimal Apparatus Diseases / pathology
  • [MeSH-minor] Aged. Apocrine Glands / pathology. Blepharoptosis / etiology. Cell Differentiation. Diagnosis, Differential. Fatal Outcome. Humans. Incidental Findings. Male. Recurrence. Stroke / complications. Stroke / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 17443428.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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9. Tuncel A, Sezgin T, Uzum N, Ataoglu O, Atan A: Primary apocrine adenocarcinoma of the scrotum with distant metastasis: a case report. Can J Urol; 2009 Oct;16(5):4860-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary apocrine adenocarcinoma of the scrotum with distant metastasis: a case report.
  • In histopathological examination, apocrine adenocarcinoma was diagnosed.
  • [MeSH-major] Adenocarcinoma / secondary. Apocrine Glands. Bone Neoplasms / secondary. Liver Neoplasms / secondary. Scrotum. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Fatal Outcome. Humans. Male. Middle Aged. Tomography, X-Ray Computed. Urologic Surgical Procedures, Male / methods

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  • (PMID = 19796468.001).
  • [ISSN] 1195-9479
  • [Journal-full-title] The Canadian journal of urology
  • [ISO-abbreviation] Can J Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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10. Alsaad KO, Obaidat N, Dube V, Chapman W, Ghazarian D: Vulvar apocrine adenocarcinoma: a case with nodal metastasis and intranodal mucinous differentiation. Pathol Res Pract; 2009;205(2):131-5
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  • [Title] Vulvar apocrine adenocarcinoma: a case with nodal metastasis and intranodal mucinous differentiation.
  • Rare cases of adenocarcinoma with apocrine features have been reported, and whether these neoplasms originate from the "native apocrine" sweat glands or from "anogenital mammary-like" glands are still debatable.
  • Absence of these features points toward native apocrine sweat glands as the source of these neoplasms.
  • In this report, we present a patient who was initially diagnosed with Paget's disease of the right vulva, which was treated by hemi-vulvectomy, and who later presented with primary vulvar apocrine adenocarcinoma with metastasis to the inguinal lymph nodes and intranodal mucinous/colloidal differentiation: a feature, to the best of our knowledge, not reported before.
  • [MeSH-major] Adenocarcinoma / pathology. Apocrine Glands / pathology. Lymphatic Metastasis / pathology. Vulvar Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma, Mucinous / metabolism. Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / surgery. Aged, 80 and over. Arthritis, Rheumatoid / complications. Cell Differentiation. Female. Gynecologic Surgical Procedures. Humans. Hypertension / complications. Osteoporosis / complications. Paget Disease, Extramammary / complications

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  • (PMID = 18842349.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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11. Nakata M, Miwa Y, Nakayama H, Sakai T, Sasaki N: Localised radiotherapy for a ferret with possible anal sac apocrine adenocarcinoma. J Small Anim Pract; 2008 Sep;49(9):476-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Localised radiotherapy for a ferret with possible anal sac apocrine adenocarcinoma.
  • On histopathology, the masses were diagnosed as apocrine adenocarcinoma possibly of anal gland origin based on tumour location.
  • Cytology of a sample of the pleural effusion suggested mesothelioma, and no obvious pulmonary metastasis of anal sac adenocarcinoma were identified on thoracic radiography.
  • [MeSH-major] Adenocarcinoma / veterinary. Anal Gland Neoplasms / radiotherapy. Anal Sacs. Ferrets

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  • (PMID = 18631226.001).
  • [ISSN] 0022-4510
  • [Journal-full-title] The Journal of small animal practice
  • [ISO-abbreviation] J Small Anim Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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12. Pucevich B, Catinchi-Jaime S, Ho J, Jukic DM: Invasive primary ductal apocrine adenocarcinoma of axilla: a case report with immunohistochemical profiling and a review of literature. Dermatol Online J; 2008;14(6):5
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for apocrine adenocarcinoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Invasive primary ductal apocrine adenocarcinoma of axilla: a case report with immunohistochemical profiling and a review of literature.
  • Primary cutaneous ductal apocrine adenocarcinoma (PCDAA) is a rare malignant cutaneous neoplasm usually arising in areas of high apocrine gland density.
  • There have been a total of 40 cases of primary apocrine adenocarcinoma reported in the literature; many are indolent and slowly- developing, but some are rapidly progressive.
  • Primary cutaneous ductal apocrine adenocarcinoma has distinctive histologic and immunohistochemical characteristics and the treatment of choice for PCDAA is wide local excision with clear margins.
  • We present a case of a 92-year-old female with a 1-year history of a subcutaneous tumor of the right axilla, histologically consistent with a diagnosis of PCDAA arising in an accessory nipple.
  • To our knowledge this is the first reported case of apocrine adenocarcinoma to develop in an accessory nipple.
  • [MeSH-major] Adenocarcinoma / pathology. Apocrine Glands. Axilla. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Neoplasm Invasiveness

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  • (PMID = 18713586.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
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13. Ogino T, Noura S, Ohue M, Matsumura M, Ishiguro S, Kishi K, Takachi K, Eguchi H, Yamada T, Miyashiro I, Yano M, Ohigashi H, Sasaki Y, Ishikawa O, Imaoka S: [A case of apocrine adenocarcinoma suspected as an axillary lymph node metastasis from cecal cancer]. Gan To Kagaku Ryoho; 2006 Nov;33(12):1968-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of apocrine adenocarcinoma suspected as an axillary lymph node metastasis from cecal cancer].
  • Biopsy of the tumor showed the features of metastatic adenocarcinoma.
  • Axillary tumor was diagnosed not as metastasis of axillary lymph nodes from cecal cancer but apocrine adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Apocrine Glands. Cecal Neoplasms / pathology. Lymphatic Metastasis
  • [MeSH-minor] Aged. Axilla. Colonoscopy. Diagnosis, Differential. Humans. Male. Neoplasms, Multiple Primary / diagnosis. Sweat Gland Neoplasms / secondary

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  • (PMID = 17212162.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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14. Akhtar I, Ispas CL, Flowers R, Siddiqi A, Young L, Donnellan KA, Heard K, Baliga M: Ductopapillary apocrine carcinoma of the eyelid metastatic to the parotid gland: report of a case diagnosed by fine-needle aspiration biopsy. Diagn Cytopathol; 2009 Feb;37(2):91-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ductopapillary apocrine carcinoma of the eyelid metastatic to the parotid gland: report of a case diagnosed by fine-needle aspiration biopsy.
  • Ductopapillary apocrine carcinoma (DPAC) of the eyelid is a rare malignant neoplasm in the periocular region.
  • The relative rarity of this tumor is a diagnostic challenge to the cytopathologist, especially when present as a metastatic lesion to an intraparotid lymph node, where the differential diagnosis includes primary parotid neoplasms, as well as various other metastatic malignancies.
  • We report a case of a 65-year-old African-American male with a history of ductopapillary apocrine adenocarcinoma of the eyelid, diagnosed 6 weeks ago now presenting with a recurrence in the same area.
  • FNAB of the parotid mass showed a well-differentiated papillary adenocarcinoma with a cystic component, similar to a previously excised ductopapillary apocrine adenocarcinoma of the eyelid.
  • [MeSH-major] Carcinoma, Papillary / diagnosis. Eyelid Neoplasms / diagnosis. Neoplasm Recurrence, Local / diagnosis. Parotid Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 19021198.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carrier Proteins; 0 / Glycoproteins; 0 / PIP protein, human
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15. Akcay EK, Simsek S, Cagil N, Belenli O, Gumus M: Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus. Can J Ophthalmol; 2008 Oct;43(5):609-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus.

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  • (PMID = 18982051.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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16. Miyamoto T, Adachi K, Fujishima M: Axillary apocrine carcinoma with Paget's disease and apocrine naevus. Clin Exp Dermatol; 2009 Jul;34(5):e110-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Axillary apocrine carcinoma with Paget's disease and apocrine naevus.
  • Apocrine carcinoma is a rare malignant sweat-gland neoplasm with apocrine differentiation.
  • There have been some reported cases of apocrine carcinoma with apocrine naevus.
  • The resected specimen showed apocrine adenocarcinoma with extramammary Paget's disease and apocrine naevus.
  • On resection of this enlarging right axilla, an apocrine naevus was found.
  • [MeSH-major] Adenocarcinoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Nevus / diagnosis. Paget Disease, Extramammary / diagnosis. Skin Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Aged. Apocrine Glands. Axilla. Humans. Male. Positron-Emission Tomography. Precancerous Conditions / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 19438526.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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17. Pinches MD, Liebenberg G, Stidworthy MF: What is your diagnosis? Preputial mass in a ferret. Vet Clin Pathol; 2008 Dec;37(4):443-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] What is your diagnosis? Preputial mass in a ferret.
  • The cytologic features were consistent with a carcinoma of probable apocrine origin.
  • Histopathologic examination supported a diagnosis of secretory apocrine adenocarcinoma of the preputial skin.
  • Secretory apocrine adenocarcinomas of the prepuce are seen relatively frequently in ferrets, although their cytologic appearance has not been described widely.

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  • (PMID = 19055582.001).
  • [ISSN] 0275-6382
  • [Journal-full-title] Veterinary clinical pathology
  • [ISO-abbreviation] Vet Clin Pathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Pornpanich K, Chindasub P: Eyelid tumors in Siriraj Hospital from 2000-2004. J Med Assoc Thai; 2005 Nov;88 Suppl 9:S11-4

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  • These 32 malignant eyelid tumors included 13 sebaceous gland carcinomas, 12 basal cell carcinomas, 3 malignant melanomas, 2 squamous cell carcinomas, 1 apocrine adenocarcinoma and 1 metastatic carcinoma.

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  • (PMID = 16681045.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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19. Fernandez-Flores A, Pol A, Juanes F, Crespo LG: Immunohistochemical phenotype of cutaneous cribriform carcinoma with a panel of 15 antibodies. Med Mol Morphol; 2007 Dec;40(4):212-7
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  • The patient did not present any symptoms, and the only complaint was the nodule, which was resected for diagnosis.
  • In spite of these characteristics, which are, for some authors, indicative of an apocrine phenotype, the immunohistochemical study revealed some differences with the profile that has been described in cases of apocrine adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / immunology. Adenocarcinoma / pathology. Antibodies, Neoplasm / immunology. Skin Neoplasms / immunology. Skin Neoplasms / pathology

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  • (PMID = 18085381.001).
  • [ISSN] 1860-1480
  • [Journal-full-title] Medical molecular morphology
  • [ISO-abbreviation] Med Mol Morphol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm
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20. Hou JL, Wu LY, Zhang HT, Lv NN, Huang Y, Yu GZ: Clinicopathologic characteristics of 12 patients with vulvar sweat gland carcinoma. Int J Gynecol Cancer; 2010 Jul;20(5):874-8
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  • Of the 12 cases, 7 cases were vulvar sweat gland carcinoma, 3 cases were vulvar Paget disease with underlying sweat gland adenocarcinoma, 1 case was vulvar apocrine adenocarcinoma, and 1 case was adenoid cystic carcinoma of the vulvar sweat gland.
  • [MeSH-major] Sweat Gland Neoplasms / diagnosis. Vulvar Neoplasms / diagnosis

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  • (PMID = 20606537.001).
  • [ISSN] 1525-1438
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Hernandez JM, Copeland EM 3rd: Infiltrating apocrine adenocarcinoma with extramammary pagetoid spread. Am Surg; 2007 Mar;73(3):307-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infiltrating apocrine adenocarcinoma with extramammary pagetoid spread.
  • Apocrine adenocarcinoma is a rare malignancy with invasive potential.
  • Its clinical behavior and histologic appearance are highly variable, making accurate diagnosis difficult.
  • We report on a case of apocrine carcinoma presenting with lymph node infiltration and extensive extramammary Paget's disease.
  • [MeSH-major] Adenocarcinoma / pathology. Apocrine Glands. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Groin. Humans. Male. Neoplasm Invasiveness. Sentinel Lymph Node Biopsy

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  • (PMID = 17375797.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Morandi F, Benazzi C, Simoni P: Adenocarcinoma of apocrine sweat glands in a mouflon (Ovis musimon). J Vet Diagn Invest; 2005 Jul;17(4):389-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of apocrine sweat glands in a mouflon (Ovis musimon).
  • On the basis of histological and ultrastructural findings, this tumor was diagnosed as a tubulopapillary adenocarcinoma, arising from apocrine sweat glands of the skin.
  • [MeSH-major] Adenocarcinoma / veterinary. Apocrine Glands. Sheep Diseases / diagnosis. Sweat Gland Neoplasms / veterinary

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  • (PMID = 16131002.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Maury G, Guillot B, Bessis D, Cribier B, Girard C: [Unusual axillary apocrine carcinoma of the skin: histological diagnostic difficulties]. Ann Dermatol Venereol; 2010 Aug-Sep;137(8-9):555-9

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  • [Title] [Unusual axillary apocrine carcinoma of the skin: histological diagnostic difficulties].
  • [Transliterated title] Carcinome apocrine cutané axillaire inhabituel : difficultés diagnostiques histologiques.
  • BACKGROUND: Apocrine carcinoma of the skin (ACS) is a rare adnexal neoplasm presenting as an indurated slow-growing dermal or subcutaneous plaque that often occurs in the axilla.
  • The pattern of the tumour and immunohistochemical staining suggested a diagnosis of breast carcinoma metastasis.
  • However, the history of a slow-growing tumour and negative initial testing for a primary adenocarcinoma supported the hypothesis of ACS.
  • DISCUSSION: A 100 cases of ACS have been reported in the literature with the main site being the axillary area.
  • Diagnosis may be difficult since the pattern of the tumour can be misleading and immunomarkers are not always specific.
  • [MeSH-major] Carcinoma / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Axilla. Breast Neoplasms, Male / diagnosis. Carcinoma, Lobular / secondary. Diagnosis, Differential. Humans. Male. Middle Aged

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20804902.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
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24. Mellanby RJ, Craig R, Evans H, Herrtage ME: Plasma concentrations of parathyroid hormone-related protein in dogs with potential disorders of calcium metabolism. Vet Rec; 2006 Dec 16;159(25):833-8
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  • The plasma concentrations of total calcium, ionised calcium, albumin, parathyroid hormone and parathyroid hormone-related protein (PTHrp) were measured in 25 dogs with lymphoma, nine dogs with primary hyperparathyroidism and seven dogs with adenocarcinoma of the apocrine gland of the anal sac.
  • [MeSH-major] Dog Diseases / diagnosis. Hypercalcemia / veterinary. Parathyroid Hormone-Related Protein / blood
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / veterinary. Anal Sacs. Animals. Case-Control Studies. Dogs. Hyperparathyroidism / diagnosis. Hyperparathyroidism / veterinary. Lymphoma / diagnosis. Lymphoma / veterinary. Predictive Value of Tests. Sensitivity and Specificity. Sweat Gland Neoplasms / diagnosis. Sweat Gland Neoplasms / veterinary

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  • (PMID = 17172477.001).
  • [ISSN] 0042-4900
  • [Journal-full-title] The Veterinary record
  • [ISO-abbreviation] Vet. Rec.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Parathyroid Hormone-Related Protein
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25. Obaidat NA, Awamleh AA, Ghazarian DM: Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region. Eur J Dermatol; 2006 Sep-Oct;16(5):576-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region.
  • Histologically, the excised lesion showed features of tubulopapillary apocrine hidradenoma, with an area showing features of carcinoma in situ.
  • Similar to vulvar lesions, peri-anal apocrine tumours are believed to arise in mammary like glands (MLGs).
  • To the best of our knowledge, this is the first description of a peri-anal adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Sweat Gland / pathology. Anus Neoplasms / pathology. Carcinoma in Situ / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17101482.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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26. Seethala RR, Richmond JA, Hoschar AP, Barnes EL: New variants of epithelial-myoepithelial carcinoma: oncocytic-sebaceous and apocrine. Arch Pathol Lab Med; 2009 Jun;133(6):950-9
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  • [Title] New variants of epithelial-myoepithelial carcinoma: oncocytic-sebaceous and apocrine.
  • OBJECTIVE: To report a detailed analysis of oncocytic-sebaceous epithelial-myoepithelial carcinoma (OEMCa) and a similar, but novel, variant, apocrine epithelial-myoepithelial carcinoma (ApEMCa).
  • CONCLUSIONS: Oncocytic-sebaceous epithelial-myoepithelial carcinoma and ApEMCa should be considered in the differential diagnosis of oncocytic/oncocytoid salivary gland tumors.
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Apocrine Glands / pathology. Carcinoma / pathology. Myoepithelioma / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Diagnosis, Differential. Humans. Immunohistochemistry. Microscopy, Electron, Transmission. Middle Aged


27. Sendagorta E, Herranz P, Feito M, Ramírez P, Floristán U, Feltes R, Benito DM, Casado M: Successful treatment of three cases of primary extramammary Paget's disease of the vulva with Imiquimod--proposal of a therapeutic schedule. J Eur Acad Dermatol Venereol; 2010 Apr;24(4):490-2
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  • BACKGROUND/AIM: Extramammary Paget's disease (EMPD) is an intraepidermal adenocarcinoma of apocrine gland-bearing skin.

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  • (PMID = 19840203.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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28. Amonkar GP, Amonkar PP, Rege JD: Bilateral axillary apocrine nevi--a case report. Indian J Pathol Microbiol; 2005 Jan;48(1):22-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral axillary apocrine nevi--a case report.
  • Apocrine glands are tubular glands, which function as scent glands.
  • Occasionally, apocrine glands are found on the face, in the scalp and on the abdomen where they are usually small and non-functional.
  • Apocrine glands develop their secretory portion and become functional only at puberty.
  • Tumours of these glands involving only apocrine tissue are very rare.
  • We present an uncommon case of benign apocrine nevi of the axilla, which occurred bilaterally.
  • [MeSH-major] Adenocarcinoma / pathology. Apocrine Glands / pathology. Axilla / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 16758779.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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29. Roy S, Shafi NQ, Rose MG: Locally recurrent and metastatic apocrine-gland carcinoma in an elderly man. Nat Clin Pract Oncol; 2007 Jan;4(1):56-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Locally recurrent and metastatic apocrine-gland carcinoma in an elderly man.
  • DIAGNOSIS: Carcinoma of the axillary apocrine gland.
  • [MeSH-major] Adenocarcinoma / pathology. Apocrine Glands. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Axilla. Diagnosis, Differential. Humans. Lymphatic Diseases / diagnosis. Male. Neoplasm Metastasis. Neoplasm Recurrence, Local

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  • (PMID = 17183356.001).
  • [ISSN] 1743-4262
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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30. Kaya H, Bozkurt SU, Erbarut I, Djamgoz MB: Apocrine carcinomas of the breast in Turkish women: hormone receptors, c-erbB-2 and p53 immunoexpression. Pathol Res Pract; 2008;204(6):367-71
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  • [Title] Apocrine carcinomas of the breast in Turkish women: hormone receptors, c-erbB-2 and p53 immunoexpression.
  • The aims of this study were twofold: (i) to determine the occurrence frequency of apocrine carcinoma of the breast (ApBCa) in Turkish breast cancer (BCa) patients; and (ii) to evaluate the expression of estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR), gross cystic disease protein-15 (GCDFP-15), c-erbB-2, and p53 in these cases.
  • [MeSH-major] Adenocarcinoma / metabolism. Breast Neoplasms / metabolism. Receptor, ErbB-2 / metabolism. Receptors, Steroid / metabolism. Sweat Gland Neoplasms / metabolism. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Adult. Aged. Apocrine Glands / metabolism. Apocrine Glands / pathology. Biomarkers, Tumor / metabolism. Carcinoma, Ductal, Breast / metabolism. Carcinoma, Ductal, Breast / pathology. Carrier Proteins / metabolism. Female. Glycoproteins / metabolism. Humans. Immunoenzyme Techniques. Middle Aged

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  • (PMID = 18342452.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carrier Proteins; 0 / Glycoproteins; 0 / PIP protein, human; 0 / Receptors, Steroid; 0 / Tumor Suppressor Protein p53; EC 2.7.10.1 / Receptor, ErbB-2
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31. Somasundaram SK, Balasubramanian RK, Aref F, Karim S, Vashisht R: A rare and unusual case of bilateral, axillary, metachronous apocrine carcinoma. Int Surg; 2007 Nov-Dec;92(6):335-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare and unusual case of bilateral, axillary, metachronous apocrine carcinoma.
  • Apocrine carcinoma is a rare sweat gland neoplasm with very few cases reported in the published literature.
  • We report a case of primary axillary apocrine carcinoma with later recurrences in both axillae.
  • A 55-year-old man was clinically diagnosed with hydradenitis suppurativa in the right axilla, and after excision of lesion, histology showed metastatic adenocarcinoma of probable breast origin.
  • [MeSH-major] Adenocarcinoma / secondary. Apocrine Glands / pathology. Breast Neoplasms, Male / pathology. Neoplasms, Second Primary. Sweat Gland Neoplasms / secondary

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  • (PMID = 18402127.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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32. Francisco JS, Alfaro SE, Oliveira DC, Tonon S, Dias EP: Apocrine carcinoma in the parotid gland and in the submandibular region. Braz J Otorhinolaryngol; 2005 Mar-Apr;71(2):224-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apocrine carcinoma in the parotid gland and in the submandibular region.
  • The objectives of this paper are to report a case of apocrine carcinoma and the discussion of aspects related to its diagnosis, treatment, and prognosis.
  • Carcinomas with apocrine differentiation not related to extramammary Paget's disease, ductal breast carcinoma, Moll's glands adenocarcinoma and ceruminous glands carcinoma are very uncommon tumors.
  • We report a case of a 51-year-old black woman who developed apocrine carcinoma lesions in the head and neck region.
  • Based on cutaneous apocrine carcinoma compatibility of the microscopic aspects, we concluded that the tumor in the submandibular skin was probably the primary neoplasm.
  • [MeSH-major] Apocrine Glands. Carcinoma / pathology. Mouth Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 16446921.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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33. Haji BE, Das DK, Al-Ayadhy B, Pathan SK, George SG, Mallik MK, Abdeen SM: Fine-needle aspiration cytologic features of four special types of breast cancers: mucinous, medullary, apocrine, and papillary. Diagn Cytopathol; 2007 Jul;35(7):408-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration cytologic features of four special types of breast cancers: mucinous, medullary, apocrine, and papillary.
  • In mucinous carcinoma, the frequency of signet ring cells (62.5%), and background pools of mucin (87.5%) were significantly higher than those of duct cell carcinoma (NOS), medullary carcinoma, apocrine carcinoma, and papillary carcinoma (P = 0.0408 to < 0.0001).
  • In medullary carcinomas, lymphomononuclear cell infiltration (100.0%) was observed in significantly higher number of cases than in papillary, mucinous, and apocrine types (P < 0.0001).
  • Abnormal apocrine cells and papillary formation, characterizing all the apocrine carcinomas and papillary carcinomas, respectively, were present in significantly lower number in other variants and in duct cell carcinoma (NOS) (P = 0.0002 to <0.0001).
  • Glycogen vacuoles (63.6%) were observed in a significantly higher number of papillary carcinoma as compared to duct cell carcinoma (NOS), apocrine, and medullary carcinomas (P = 0.0047 to 0.0022).
  • Thus, special and unusual variants of duct cell carcinomas like mucinous, medullary, apocrine, and papillary have specific cytomorphological features, which differentiate them from one another and from duct cell carcinoma (NOS).
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Apocrine Glands / pathology. Biopsy, Fine-Needle. Breast Neoplasms / pathology. Carcinoma, Medullary / pathology. Carcinoma, Papillary / pathology

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  • (PMID = 17580344.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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34. Adamski H, Le Lan J, Chevrier S, Cribier B, Watier E, Chevrant-Breton J: Primary cutaneous cribriform carcinoma: a rare apocrine tumour. J Cutan Pathol; 2005 Sep;32(8):577-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cutaneous cribriform carcinoma: a rare apocrine tumour.
  • BACKGROUND: Primary cutaneous cribriform carcinoma (PCCC) is a rare apocrine tumour occurring in middle-aged people.
  • The histopathological diagnosis is difficult, mainly because this tumour is exceptional.
  • After a 2-year follow-up, neither persistence at the local site nor metastasis was observed.
  • Differential diagnoses, including cutaneous metastasis of adenocarcinoma, adenoid basal cell carcinoma and adenoid cystic carcinoma, are discussed.
  • [MeSH-major] Adenocarcinoma / pathology. Apocrine Glands / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Basal Cell / diagnosis. Diagnosis, Differential. Humans. Male. Treatment Outcome

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  • (PMID = 16115058.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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35. Robson A, Lazar AJ, Ben Nagi J, Hanby A, Grayson W, Feinmesser M, Granter SR, Seed P, Warneke CL, McKee PH, Calonje E: Primary cutaneous apocrine carcinoma: a clinico-pathologic analysis of 24 cases. Am J Surg Pathol; 2008 May;32(5):682-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cutaneous apocrine carcinoma: a clinico-pathologic analysis of 24 cases.
  • Primary cutaneous apocrine carcinoma is a rare malignancy.
  • [MeSH-major] Adenocarcinoma / pathology. Apocrine Glands / pathology. Sweat Gland Neoplasms / pathology

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  • [CommentIn] Am J Surg Pathol. 2009 Jan;33(1):155-7 [18971780.001]
  • (PMID = 18347508.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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36. Zelger BG, Stelzmueller I, Dunst KM, Zelger B: Solid apocrine carcinoma of the skin: report of a rare adnexal neoplasm mimicking lobular breast carcinoma. J Cutan Pathol; 2008 Mar;35(3):332-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solid apocrine carcinoma of the skin: report of a rare adnexal neoplasm mimicking lobular breast carcinoma.
  • The differentiation between apocrine and eccrine neoplasms remains difficult.
  • After further clinical and laboratory work up including immunohistochemistry the original diagnosis of a breast cancer had to be changed to solid apocrine carcinoma of the skin.
  • Solid apocrine carcinoma of the skin is a rare variant with apocrine differentiation.
  • A survey of the stereotypical presentation of this lesion and a comparison with lobular breast carcinoma and other types of apocrine carcinoma of the skin is given.
  • [MeSH-major] Adenocarcinoma / diagnosis. Apocrine Glands / pathology. Breast Neoplasms, Male / diagnosis. Carcinoma, Lobular / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Diagnosis, Differential. Disease-Free Survival. Humans. Immunohistochemistry. Male

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  • (PMID = 18251751.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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37. Wright ZM, Fryer JS, Calise DV, Oliveira FN: Carboplatin chemotherapy in a cat with a recurrent anal sac apocrine gland adenocarcinoma. J Am Anim Hosp Assoc; 2010 Jan-Feb;46(1):66-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carboplatin chemotherapy in a cat with a recurrent anal sac apocrine gland adenocarcinoma.
  • The mass was incompletely excised, and histological assessment resulted in a diagnosis of anal sac adenocarcinoma.
  • Necropsy confirmed the original diagnosis as well as metastasis to the regional lymph nodes and lungs.
  • [MeSH-major] Adenocarcinoma / drug therapy. Adenocarcinoma / veterinary. Anal Gland Neoplasms / drug therapy. Antineoplastic Agents / therapeutic use. Carboplatin / therapeutic use. Cat Diseases / drug therapy

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  • (PMID = 20045840.001).
  • [ISSN] 1547-3317
  • [Journal-full-title] Journal of the American Animal Hospital Association
  • [ISO-abbreviation] J Am Anim Hosp Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; BG3F62OND5 / Carboplatin
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38. Pai RR, Kini JR, Achar C, Rau A, Kini H: Apocrine (cutaneous) sweat gland carcinoma of axilla with signet ring cells: a diagnostic dilemma on fine-needle aspiration cytology. Diagn Cytopathol; 2008 Oct;36(10):739-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apocrine (cutaneous) sweat gland carcinoma of axilla with signet ring cells: a diagnostic dilemma on fine-needle aspiration cytology.
  • Carcinoma arising in the apocrine sweat glands is rare and there are few reports describing the cytological features of this neoplasm.
  • We describe the cytological features of a histologically confirmed apocrine carcinoma occurring in a 55-year-old man who presented with an ulcerated mass in the right axilla.
  • Fine-needle aspiration cytology revealed features of a signet ring adenocarcinoma.
  • In an axillary mass lesion, cytological features along with clinical correlation are essential to distinguish primary apocrine carcinoma from mammary neoplasms with signet ring cells and other metastatic adenocarcinomas.
  • [MeSH-major] Axilla. Carcinoma, Signet Ring Cell / diagnosis. Carcinoma, Signet Ring Cell / pathology. Sweat Gland Neoplasms / diagnosis. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Biopsy, Fine-Needle / methods. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 18773442.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Rütten A, Kutzner H, Mentzel T, Hantschke M, Eckert F, Angulo J, Rodríguez Peralto JL, Requena L: Primary cutaneous cribriform apocrine carcinoma: a clinicopathologic and immunohistochemical study of 26 cases of an under-recognized cutaneous adnexal neoplasm. J Am Acad Dermatol; 2009 Oct;61(4):644-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cutaneous cribriform apocrine carcinoma: a clinicopathologic and immunohistochemical study of 26 cases of an under-recognized cutaneous adnexal neoplasm.
  • BACKGROUND: Cribriform carcinoma is the histopathologic variant of cutaneous apocrine carcinoma characterized by interconnected solid aggregations of neoplastic cells that are punctuated by small round spaces.
  • METHODS: Twenty-six cases of primary cutaneous cribriform apocrine carcinoma were clinically, histopathologically, and immunohistochemically studied.
  • CONCLUSIONS: Primary cutaneous cribriform apocrine carcinoma is a distinctive but little-known variant of cutaneous apocrine carcinoma.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Biomarkers, Tumor / metabolism. Neoplasms, Adnexal and Skin Appendage / metabolism. Neoplasms, Adnexal and Skin Appendage / pathology
  • [MeSH-minor] Adult. Aged. Apocrine Glands / pathology. Biopsy. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Cytoplasm / pathology. Cytoplasm / ultrastructure. Diagnosis, Differential. Epithelial Cells / pathology. Epithelial Cells / ultrastructure. Female. Humans. Immunohistochemistry. Male. Microscopy, Electron. Microvilli / pathology. Microvilli / ultrastructure. Middle Aged. Young Adult

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  • [CommentIn] J Am Acad Dermatol. 2011 Mar;64(3):599-601 [21315957.001]
  • (PMID = 19751882.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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40. Gál J, Mándoki M, Sátorhelyi T, Jakab C: In situ complex adenocarcinoma on the femoral part of the hindlimb in an Asian Leaf Turtle (Cyclemys dentata). Acta Vet Hung; 2010 Dec;58(4):431-40

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  • [Title] In situ complex adenocarcinoma on the femoral part of the hindlimb in an Asian Leaf Turtle (Cyclemys dentata).
  • A heterotopic in situ complex adenocarcinoma developing on the hindlimb is reported for the first time from an Asian Leaf Turtle (Cyclemys dentata).
  • Histopathology of the tumour revealed all characteristics of a well-differentiated adenocarcinoma originating from apocrine gland-like tissue: the irregular, tubular structures varying in size were generally lined by two to four layers of cuboidal to columnar neoplastic epithelial cells.
  • The diagnosis was a complex adenocarcinoma originating from apocrine gland-like tissue in a turtle.
  • [MeSH-major] Adenocarcinoma / veterinary. Hindlimb / pathology. Soft Tissue Neoplasms / veterinary. Turtles

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  • (PMID = 21087913.001).
  • [ISSN] 0236-6290
  • [Journal-full-title] Acta veterinaria Hungarica
  • [ISO-abbreviation] Acta Vet. Hung.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Hungary
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41. Neihaus SA, Winter JE, Goring RL, Kennedy FA, Kiupel M: Primary clitoral adenocarcinoma with secondary hypercalcemia of malignancy in a dog. J Am Anim Hosp Assoc; 2010 May-Jun;46(3):193-6
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  • [Title] Primary clitoral adenocarcinoma with secondary hypercalcemia of malignancy in a dog.
  • This report describes a primary clitoral adenocarcinoma in a dog with secondary hypercalcemia of malignancy.
  • The mass was excised, and a histological diagnosis of clitoral adenocarcinoma was made.
  • Cellular features were similar to an apocrine gland anal sac adenocarcinoma, and immunohistochemistry exhibited features noted with apocrine gland anal sac adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / veterinary. Clitoris. Dog Diseases / diagnosis. Hypercalcemia / veterinary. Vulvar Neoplasms / veterinary

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  • (PMID = 20439943.001).
  • [ISSN] 1547-3317
  • [Journal-full-title] Journal of the American Animal Hospital Association
  • [ISO-abbreviation] J Am Anim Hosp Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Hobson HP, Brown MR, Rogers KS: Surgery of metastatic anal sac adenocarcinoma in five dogs. Vet Surg; 2006 Apr;35(3):267-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgery of metastatic anal sac adenocarcinoma in five dogs.
  • OBJECTIVE: To identify survival and morbidity information after surgery for metastases from apocrine gland anal sac adenocarcinomas (AGACA).
  • CONCLUSION: Dogs with anal sac adenocarcinoma metastases to the iliac lymph nodes can experience long-term survival after surgical excision of the metastatic lesion.
  • CLINICAL RELEVANCE: Lymphadenectomy may afford long-term survival to patients with metastatic anal sac adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / veterinary. Anal Gland Neoplasms / surgery. Anal Sacs. Dog Diseases / surgery

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  • [CommentIn] Compend Contin Educ Vet. 2008 Feb;30(2):69, 72 [23713167.001]
  • (PMID = 16635006.001).
  • [ISSN] 0161-3499
  • [Journal-full-title] Veterinary surgery : VS
  • [ISO-abbreviation] Vet Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. do Val IC, Almeida Filho GL, Corrêa A, Neto N: Chronic hidradenitis suppurativa and perianal mucinous adenocarcinoma. A case report. J Reprod Med; 2007 Feb;52(2):100-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chronic hidradenitis suppurativa and perianal mucinous adenocarcinoma. A case report.
  • BACKGROUND: Hidradenitis is a chronic and suppurative inflammation of the apocrine sudoriparous glands.
  • This is the first case report of hidradenitis suppurativa in the vulvar region associated with perianal mucinous adenocarcinoma.
  • A diagnosis of perianal mucinous adenocarcinoma was made.
  • [MeSH-major] Adenocarcinoma, Mucinous / etiology. Hidradenitis Suppurativa / complications. Skin Neoplasms / etiology

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  • (PMID = 17393769.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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44. Chanjuan Shi, Argani P: Synchronous primary perianal Paget's disease and rectal adenocarcinoma: report of a hitherto undescribed phenomenon. Int J Surg Pathol; 2009 Feb;17(1):42-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous primary perianal Paget's disease and rectal adenocarcinoma: report of a hitherto undescribed phenomenon.
  • It usually represents intraepidermal extension of an invasive carcinoma from an adjacent internal organ, but some cases represent primary intraepithelial cutaneous apocrine adenocarcinomas.
  • Here, we report a unique case, which we interpret as synchronous primary perianal Paget's disease and lower rectal adenocarcinoma.
  • Immunohistochemical stains demonstrated that the Paget's cells were CK7+/ CK20-/GCDFP+, whereas the rectal adenocarcinoma was CK7+(variable)/CK20+/GCDFP-.
  • This discordant immunoprofile supported our impression that the Paget's disease in this patient was of cutaneous apocrine origin rather than a pagetoid extension from the patient's nearby rectal adenocarcinoma-to our knowledge a hitherto undocumented occurrence.
  • [MeSH-major] Adenocarcinoma / diagnosis. Anal Canal. Neoplasms, Multiple Primary / diagnosis. Paget Disease, Extramammary / diagnosis. Rectal Neoplasms / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18499687.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carrier Proteins; 0 / Glycoproteins; 0 / Keratin-20; 0 / Keratin-7; 0 / PIP protein, human
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45. Carvalho J, Fullen D, Lowe L, Su L, Ma L: The expression of CD23 in cutaneous non-lymphoid neoplasms. J Cutan Pathol; 2007 Sep;34(9):693-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In our routine practice, we observed that CD23 reacted strongly with eccrine and apocrine secretory coils.
  • METHODS: Immunohistochemical staining of CD23 was performed in a total of 131 cases of apocrine, eccrine, follicular and other cutaneous non-lymphoid tumors.
  • RESULTS: CD23 expression was detected in all benign apocrine tumors and in half of benign eccrine tumors, particularly those derived from secretory coils.
  • In addition, CD23 reacted diffusely with cutaneous mucinous eccrine carcinoma in a manner similar to breast or colonic adenocarcinoma.
  • CONCLUSION: CD23 appears to be a reliable immunohistochemical marker of the eccrine/apocrine secretory coil and helpful in identifying sweat gland tumors of such origin.
  • [MeSH-minor] Apocrine Glands / metabolism. Apocrine Glands / pathology. Eccrine Glands / metabolism. Eccrine Glands / pathology. Humans

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  • (PMID = 17696916.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, IgE
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46. Ivan D, Nash JW, Prieto VG, Calonje E, Lyle S, Diwan AH, Lazar AJ: Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin. J Cutan Pathol; 2007 Jun;34(6):474-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin.
  • Metastases from two apocrine carcinomas lacked p63 expression.
  • Analysis of p63 expression may assist in the differential diagnosis of primary adnexal carcinomas versus metastatic visceral adenocarcinomas to the skin.
  • [MeSH-major] Adenocarcinoma, Mucinous / metabolism. Biomarkers, Tumor / metabolism. DNA-Binding Proteins / metabolism. Neoplasms, Adnexal and Skin Appendage / metabolism. Skin Neoplasms / metabolism. Trans-Activators / metabolism. Tumor Suppressor Proteins / metabolism
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Immunoenzyme Techniques. Retrospective Studies. Transcription Factors

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  • [CommentIn] J Cutan Pathol. 2008 Jul;35(7):692-3 [18312438.001]
  • (PMID = 17518775.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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47. Bratthauer GL, Saenger JS, Strauss BL: Antibodies targeting p63 react specifically in the cytoplasm of breast epithelial cells exhibiting secretory differentiation. Histopathology; 2005 Dec;47(6):611-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This reaction was not seen in cells undergoing apocrine differentiation or in other cells containing secretory vacuoles.
  • [MeSH-minor] Adenocarcinoma, Clear Cell / metabolism. Adenocarcinoma, Clear Cell / pathology. Adenocarcinoma, Mucinous / metabolism. Adenocarcinoma, Mucinous / pathology. Breast Neoplasms / metabolism. Breast Neoplasms / pathology. Carcinoma / chemistry. Carcinoma / pathology. Carcinoma, Intraductal, Noninfiltrating / metabolism. Carcinoma, Intraductal, Noninfiltrating / pathology. Carcinoma, Lobular / metabolism. Carcinoma, Lobular / pathology. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Cytoplasm / metabolism. DNA-Binding Proteins. Epithelial Cells / cytology. Epithelial Cells / metabolism. Female. Fibrocystic Breast Disease / metabolism. Fibrocystic Breast Disease / pathology. Humans. Immunohistochemistry. Neoplasm Invasiveness. Transcription Factors. Tumor Suppressor Proteins

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  • (PMID = 16324199.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies; 0 / DNA-Binding Proteins; 0 / Phosphoproteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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48. Newkirk KM, Rohrbach BW: A retrospective study of eyelid tumors from 43 cats. Vet Pathol; 2009 Sep;46(5):916-27
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The average age at diagnosis was 10.4 years.
  • There were 12 squamous cell carcinomas (SCCs), 11 mast cell tumors (MCTs), 6 hemangiosarcomas (HSAs), 4 adenocarcinomas (ACAs), 3 peripheral nerve sheath tumors (PNSTs), 3 lymphomas, 3 apocrine hidrocystomas (AHCs), and 2 hemangiomas.
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Adenocarcinoma / veterinary. Animals. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / veterinary. Cats. Female. Hemangiosarcoma / epidemiology. Hemangiosarcoma / pathology. Hemangiosarcoma / veterinary. Hidrocystoma / epidemiology. Hidrocystoma / pathology. Hidrocystoma / veterinary. Immunohistochemistry / veterinary. Lymphoma / epidemiology. Lymphoma / pathology. Lymphoma / veterinary. Male. Mastocytosis / epidemiology. Mastocytosis / pathology. Nerve Sheath Neoplasms / epidemiology. Nerve Sheath Neoplasms / pathology. Nerve Sheath Neoplasms / veterinary. Retrospective Studies

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  • (PMID = 19429997.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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49. Emms SG: Anal sac tumours of the dog and their response to cytoreductive surgery and chemotherapy. Aust Vet J; 2005 Jun;83(6):340-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of 21 dogs with tumours of the anal sacs 19 had apocrine gland adenocarcinomas of anal sac origin, one had a benign papillary cystadenoma and another had a malignant melanoma.
  • Ten of the 19 dogs with apocrine gland adenocarcinomas of anal sac origin had sublumbar lymphadenopathy.
  • Fourteen dogs with apocrine gland adenocarcinomas of anal sac origin were treated by surgical cytoreduction and chemotherapy with melphalan.
  • This study suggests there is a role for melphalan in the treatment of dogs with anal sac adenocarcinoma when combined with cytoreductive surgery, with treatment survival times and the local recurrence rate of the primary tumour comparing favourably with previously published treatment regimes.
  • [MeSH-minor] Adenocarcinoma / veterinary. Animals. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Combined Modality Therapy. Cystadenoma, Papillary / veterinary. Dogs. Female. Male. Melanoma / veterinary. Neoplasm Metastasis. Records as Topic / veterinary. Retrospective Studies. Survival Analysis. Victoria / epidemiology

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  • (PMID = 15986909.001).
  • [ISSN] 0005-0423
  • [Journal-full-title] Australian veterinary journal
  • [ISO-abbreviation] Aust. Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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50. Iwase H, Kurebayashi J, Tsuda H, Ohta T, Kurosumi M, Miyamoto K, Yamamoto Y, Iwase T: Clinicopathological analyses of triple negative breast cancer using surveillance data from the Registration Committee of the Japanese Breast Cancer Society. Breast Cancer; 2010 Apr;17(2):118-24
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  • Apocrine carcinoma was also found very frequently in the TN group.
  • CONCLUSIONS: Although TN types are similar to basal-like breast tumor, as determined by gene profiling, their diagnosis needs verification by determination of the level of epidermal growth factor receptor or cytokeratin 5/6 expression.
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenocarcinoma, Scirrhous / metabolism. Adenocarcinoma, Scirrhous / pathology. Adult. Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / metabolism. Carcinoma / metabolism. Carcinoma / pathology. Carcinoma, Intraductal, Noninfiltrating / metabolism. Carcinoma, Intraductal, Noninfiltrating / pathology. Carcinoma, Lobular / metabolism. Carcinoma, Lobular / pathology. Female. Humans. Japan. Middle Aged. Prognosis. Receptor, ErbB-2 / metabolism. Registries. Societies, Medical / statistics & numerical data. Young Adult


51. Zhang HZ, Jiang ZM, Guo MY, Zheng L: [Electron microscopic examination on 50 cases of prostatic needle biopsies]. Zhonghua Bing Li Xue Za Zhi; 2010 Sep;39(9):587-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Similar to their counterparts in benign prostatic cells, prostasomes and storage vesicles in prostatic carcinoma cells were formed in the Golgi apparatus and released into the lumen by apocrine excretion and exocytosis.
  • [MeSH-major] Adenocarcinoma / ultrastructure. Prostate / ultrastructure. Prostatic Hyperplasia / pathology. Prostatic Intraepithelial Neoplasia / ultrastructure. Prostatic Neoplasms / ultrastructure

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  • (PMID = 21092584.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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52. Strauss BL, Bratthauer GL, Tavassoli FA: STAT 5a expression in the breast is maintained in secretory carcinoma, in contrast to other histologic types. Hum Pathol; 2006 May;37(5):586-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • No expression was seen in apocrine metaplasia or in other specialized breast carcinomas, such as mucinous or clear cell carcinoma.
  • [MeSH-major] Adenocarcinoma / metabolism. Breast / metabolism. Breast Neoplasms / metabolism. STAT5 Transcription Factor / metabolism

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  • (PMID = 16647957.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / STAT5 Transcription Factor; 0 / STAT5A protein, human; 0 / Tumor Suppressor Proteins
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53. Kim ES, Lee DP, Lee MW, Choi JH, Moon KC, Koh JK: Cutaneous metastasis of uterine papillary serous carcinoma. Am J Dermatopathol; 2005 Oct;27(5):436-8
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  • Uterine papillary serous carcinoma (UPSC) is an uncommon highly malignant variant of endometrial adenocarcinoma that histologically and clinically resembles papillary serous carcinoma of the ovary.
  • A 54-year-old Korean female developed multiple pruritic skin nodules on the pubic area 13 months later after diagnosis of uterine papillary serous carcinoma.
  • Without clinical history, it is difficult to distinguish other types of metastatic carcinoma to the skin and primary apocrine carcinoma of the skin from metastatic uterine papillary serous carcinoma.
  • Whereas uterine papillary serous carcinoma only rarely involves the skin, this entity should be included in the differential diagnosis of papillary adenocarcinoma in the skin.

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  • (PMID = 16148416.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Crain N, Nelson BL, Barnes EL, Thompson LD: Ceruminous gland carcinomas: a clinicopathologic and immunophenotypic study of 17 cases. Head Neck Pathol; 2009 Mar;3(1):1-17

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  • Tumors were divided into three types of adenocarcinoma based on pattern of growth and cell type (ceruminous, NOS [n = 12], adenoid cystic [n = 4], mucoepidermoid [n = 1]).
  • Metastatic adenocarcinoma or direct extension from salivary gland neoplasms are the principle differential considerations.
  • CONCLUSION: Ceruminous-type carcinomas, with the exception of ceruminous mucoepidermoid carcinoma, all demonstrated a dual cell population of basal myoepithelial-type cells and luminal apocrine cells.

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  • (PMID = 20596983.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807538
  • [Keywords] NOTNLM ; Adenoid cystic / Carcinoma / Ceruminal / Ceruminous / Ear / Gland / Immunohistochemistry / Mucoepidermoid / Prognosis
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55. Amano K, Kumamoto K, Ohsawa T, Okada N, Ishibashi K, Inokuma S, Nakada H, Yokoyama M, Haga N, Ishida H: [The prognosis and immunohistochemical evaluation of five perianal Paget's disease cases]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2653-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Perianal Paget's disease is categorized as Paget's disease, which is epidermotropic neoplasm arising from the apocrine glands of perianal region, or Pagetoid spread invaded from rectal or anal canal cancer.
  • It has been reported that the immunohistochemical staining of GCDFP15, the marker of the apocrine epithelium, and CK20 is used to be distinguished between Paget's disease and Pagetoid spread.
  • It was compatible with the preoperative diagnosis.
  • Only one of 3 Paget's disease cases was positive for GCDFP15 and negative for CK20 resulting in the diagnosis of perianal Paget's disease.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Biomarkers, Tumor / analysis. Carrier Proteins / analysis. Glycoproteins / analysis. Keratin-20 / analysis. Paget Disease, Extramammary / diagnosis. Paget Disease, Extramammary / pathology

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  • (PMID = 21224669.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carrier Proteins; 0 / Glycoproteins; 0 / Keratin-20; 0 / PIP protein, human
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56. Ishida M, Katsura K, Nagata A, Kijima K, Kushima R, Okabe H: [A case of primary mucinous carcinoma with endocrine differentiation of the skin]. Rinsho Byori; 2008 Jun;56(6):455-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

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  • There was no tumor in the other organs and synaptophysin and chromogranin A were sporadically shown immunohistochemically in the tumor cells; a diagnosis of primary pure MCS with endocrine differentiation was made.
  • It is presumed that MCS is derived from the apocrine gland, which is closely related to the mammary gland.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Facial Neoplasms / pathology. Skin Neoplasms / pathology

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  • (PMID = 18646630.001).
  • [ISSN] 0047-1860
  • [Journal-full-title] Rinsho byori. The Japanese journal of clinical pathology
  • [ISO-abbreviation] Rinsho Byori
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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57. Chang YM, Hsu KF, Chang SC: Extra-mammary Paget's disease of the scrotum and penis: a case report. Acta Chir Belg; 2009 Nov-Dec;109(6):808-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is an intra-epithelial adenocarcinoma that involves the area rich in apocrine glands.
  • The diagnosis and treatment are discussed.

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  • (PMID = 20184077.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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58. Zhang XL, Yang GZ, Ding HY: [Pathological study of radial sclerosing lesions]. Zhonghua Bing Li Xue Za Zhi; 2010 Jan;39(1):10-3
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  • OBJECTIVE: To investigate the pathological diagnostic features and the differential diagnosis of radial sclerosing lesions of the breast.
  • Dilated tubules and proliferated ducts or lobules were seen radically arranged at the periphery accompanied sometimes with the apocrine glands or columnar cell metaplasia and hyperplasia.
  • [MeSH-minor] Adenocarcinoma / pathology. Adolescent. Adult. Breast Neoplasms / pathology. Carcinoma in Situ / pathology. Carcinoma, Ductal, Breast / pathology. Carcinoma, Lobular / pathology. Diagnosis, Differential. Diagnostic Errors. Female. Humans. Hyperplasia. Keratin-14 / metabolism. Keratins / metabolism. Middle Aged. Young Adult

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  • (PMID = 20388392.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / CK-34 beta E12; 0 / Keratin-14; 0 / Keratin-5; 68238-35-7 / Keratins
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59. Mirer E, El Sayed F, Ammoury A, Lamant L, Messer L, Bazex J: Treatment of mammary and extramammary Paget's skin disease with topical imiquimod. J Dermatolog Treat; 2006;17(3):167-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Paget's disease is an uncommon epidermal cancer, affecting all skin regions wherever apocrine glands are present.
  • It can be confined to the epithelium or may be associated with an underlying adenocarcinoma.
  • The diagnosis is confirmed by skin biopsy and the treatment depends on characteristics of the underlying cancer.
  • [MeSH-minor] Administration, Cutaneous. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Groin. Humans

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  • [CommentIn] J Dermatolog Treat. 2007;18(3):191-2 [17538811.001]
  • (PMID = 16854759.001).
  • [ISSN] 0954-6634
  • [Journal-full-title] The Journal of dermatological treatment
  • [ISO-abbreviation] J Dermatolog Treat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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60. Ho SA, Aw DC: Extramammary Paget's disease treated with topical imiquimod 5% cream. Dermatol Ther; 2010 Jul-Aug;23(4):423-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Extramammary Paget's disease (EMPD) is a rare cutaneous, intraepithelial adenocarcinoma usually found in the apocrine gland bearing areas.

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  • (PMID = 20666831.001).
  • [ISSN] 1529-8019
  • [Journal-full-title] Dermatologic therapy
  • [ISO-abbreviation] Dermatol Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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61. Ekwueme KC, Zakhour HD, Parr NJ: Extramammary Paget's disease of the penis: a case report and review of the literature. J Med Case Rep; 2009;3:4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Extramammary Paget's disease is a rare cutaneous, slow growing, intraepithelial adenocarcinoma developing in the apocrine gland-bearing areas.
  • The diagnosis was made histologically on the excised specimen and was supported by immunohistochemical staining.
  • A high index of suspicion is required, combined with biopsy and immunohistochemical staining in order to make the correct diagnosis.

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  • (PMID = 19126202.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2628937
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62. Aldewereld W, Blanken R: [Extra-mammary Paget's disease of the scrotum]. Ned Tijdschr Geneeskd; 2009;153:A919

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The diagnosis of extra-mammary Paget's disease (EMPD) was made.
  • EMPD is an intra-epidermal adenocarcinoma, found in areas with apocrine sweat glands.
  • [MeSH-major] Genital Neoplasms, Male / diagnosis. Paget Disease, Extramammary / diagnosis. Scrotum / pathology

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  • (PMID = 20051181.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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63. Bauer JA, Frye G, Bahr A, Gieg J, Brofman P: Anti-tumor effects of nitrosylcobalamin against spontaneous tumors in dogs. Invest New Drugs; 2010 Oct;28(5):694-702
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  • (1) A 13 year-old female spayed Giant Schnauzer with inoperable thyroid carcinoma and hypercalcemia. (2) A 6 year-old male neutered Golden Retriever with a malignant peripheral nerve sheath tumor (MPNST). (3) A ten yr-old neutered male Bichon Frise with apocrine gland anal sac adenocarcinoma (AGACA). (4) A 7 year-old female spayed Labrador mix with spinal meningioma following partial surgical resection.

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  • [ErratumIn] Invest New Drugs. 2011 Oct;29(5):1122
  • (PMID = 19557306.001).
  • [ISSN] 1573-0646
  • [Journal-full-title] Investigational new drugs
  • [ISO-abbreviation] Invest New Drugs
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA095020
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Nitroso Compounds; 0 / nitrosylcobalamin; P6YC3EG204 / Vitamin B 12
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64. Cham PM, Niehans GA, Foman N, Suwattee P: Primary cutaneous apocrine carcinoma presenting as carcinoma erysipeloides. Br J Dermatol; 2008 Jan;158(1):194-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cutaneous apocrine carcinoma presenting as carcinoma erysipeloides.
  • [MeSH-major] Apocrine Glands. Head and Neck Neoplasms / diagnosis. Neoplasms, Second Primary / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma. Aged, 80 and over. Colonic Neoplasms. Humans. Male

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  • (PMID = 17986301.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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65. Bagwan IN, Taylor A, Dina R: Metastatic apocrine carcinoma of female genital tract. J Clin Pathol; 2009 Mar;62(3):287-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic apocrine carcinoma of female genital tract.
  • [MeSH-major] Adenocarcinoma / secondary. Vulvar Neoplasms / pathology
  • [MeSH-minor] Aged. Apocrine Glands / pathology. Female. Humans. Liver Neoplasms / secondary. Lymphatic Metastasis

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  • (PMID = 19251959.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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66. Dugu L, Takahara M, Tsuji G, Iwashita Y, Liu X, Furue M: Abundant expression of neuronatin in normal eccrine, apocrine and sebaceous glands and their neoplasms. J Dermatol; 2010 Sep;37(9):846-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abundant expression of neuronatin in normal eccrine, apocrine and sebaceous glands and their neoplasms.
  • [MeSH-major] Adenocarcinoma, Sebaceous / metabolism. Membrane Proteins / metabolism. Nerve Tissue Proteins / metabolism. Paget Disease, Extramammary / metabolism. Poroma / metabolism. Sebaceous Gland Neoplasms / metabolism. Sebaceous Glands / metabolism. Sweat Gland Neoplasms / metabolism. Sweat Glands / metabolism. Syringoma / metabolism

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  • (PMID = 20883377.001).
  • [ISSN] 1346-8138
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Membrane Proteins; 0 / NNAT protein, human; 0 / Nerve Tissue Proteins; Sebaceous gland hyperplasia, familial presenile
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67. Bowling JC, Powles A, Nasiri N, Searle A, Bunker CB: Spontaneous regression of extramammary Paget's disease after excision of primary apocrine carcinoma, in an immunosuppressed patient. Br J Dermatol; 2005 Sep;153(3):676-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous regression of extramammary Paget's disease after excision of primary apocrine carcinoma, in an immunosuppressed patient.
  • [MeSH-major] Adenocarcinoma / surgery. Immunocompromised Host. Neoplasm Regression, Spontaneous. Paget Disease, Extramammary / pathology. Skin Neoplasms / surgery

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  • (PMID = 16120170.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] England
  • [Number-of-references] 4
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68. Magro G, Gangemi P, Greco P: Deciduoid-like myofibroblastoma of the breast: a potential pitfall of malignancy. Histopathology; 2008 Apr;52(5):652-4
MedlinePlus Health Information. consumer health - Breast Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Breast Neoplasms / diagnosis. Decidua / pathology. Neoplasms, Muscle Tissue / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Apocrine Glands / pathology. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Mammography. Middle Aged. Sweat Gland Neoplasms / diagnosis. Treatment Outcome. Ultrasonography

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  • (PMID = 18370961.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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