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1. Aloia TA, Barakat O, Connelly J, Haykal N, Michel D, Gaber AO, Ghobrial RM: Gastric radiation enteritis after intra-arterial yttrium-90 microsphere therapy for early stage hepatocellular carcinoma. Exp Clin Transplant; 2009 Sep;7(3):141-4
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  • [Title] Gastric radiation enteritis after intra-arterial yttrium-90 microsphere therapy for early stage hepatocellular carcinoma.
  • OBJECTIVES: As clinicians who treat hepatocellular carcinoma move yttrium-90 intra-arterial radiotherapy from the palliative setting to the treatment of patients with potentially curable early stage disease, more intense scrutiny of the safety of that procedure is warranted.
  • To demonstrate the potential risks associated with this treatment, in the following case report, we describe a patient with early stage hepatocellular carcinoma who experienced severe toxicity from intra-arterial radiotherapy.
  • MATERIALS AND METHODS: Screening studies in a 64-year-old Asian woman with a history of hepatitis C virus infection and cirrhosis identified a 3.5-cm well-differentiated hepatocellular carcinoma with no vascular invasion.
  • Upper endoscopy with biopsy identified antral gastritis and embolic microspheres in the submucosal layer of the gastric antrum.
  • CONCLUSIONS: This case highlights the potential risks associated with radioactive microsphere embolization in patients with hepatocellular carcinoma.
  • [MeSH-major] Carcinoma, Hepatocellular / radiotherapy. Gastritis / etiology. Liver Neoplasms / radiotherapy. Radiation Injuries / etiology. Radiopharmaceuticals / adverse effects. Yttrium Radioisotopes / adverse effects

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  • (PMID = 19715522.001).
  • [ISSN] 2146-8427
  • [Journal-full-title] Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
  • [ISO-abbreviation] Exp Clin Transplant
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0 / Yttrium Radioisotopes
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2. Muroni M, D'Angelo F, Pezzatini M, Sebastiani S, Noto S, Pilozzi E, Ramacciato G: Synchronous gastric adenocarcinoma and pancreatic ductal adenocarcinoma. Hepatobiliary Pancreat Dis Int; 2010 Feb;9(1):97-9
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The association between gastric and pancreatic carcinoma is a relatively rare condition.
  • In gastric carcinoma patients, the prevalence of second tumors varies 2.8% to 6.8% according to the reported statistics.
  • Computed tomography and magnetic resonance showed a gastric thickening in the antral and pyloric portion and a nodular mass (3 X 1.7 cm) in the uncinate portion of the pancreas.
  • [MeSH-major] Adenocarcinoma / diagnosis. Carcinoma, Pancreatic Ductal / diagnosis. Neoplasms, Multiple Primary / diagnosis. Pancreatic Neoplasms / diagnosis. Stomach Neoplasms / diagnosis

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  • (PMID = 20133238.001).
  • [ISSN] 1499-3872
  • [Journal-full-title] Hepatobiliary & pancreatic diseases international : HBPD INT
  • [ISO-abbreviation] HBPD INT
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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3. Naresse LE, Kobayasi S, Rodrigues MA: Carcinogenesis of the upper gastrointestinal tract induced by N-methyl-N'-nitro-nitrosoguanidine and reflux of duodenal contents in the rat. Acta Cir Bras; 2009 Mar-Apr;24(2):112-7
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  • The lesions obtained in the antral mucosa, at the gastrojejunal anastomosis and in the forestomach were analysed histologically.
  • MNNG treatment plus duodenal reflux enhanced the development of malignant tumors at both glandular and squamous mucosa, since there were 30% of antral adenocarcinomas and 45% of squamous carcinomas at the 18th week and the frequency of these malignant tumors rose to 50% in the antrum and 65% in the squamous mucosa at the 36th week.

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  • (PMID = 19377779.001).
  • [ISSN] 1678-2674
  • [Journal-full-title] Acta cirurgica brasileira
  • [ISO-abbreviation] Acta Cir Bras
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 12H3O2UGSF / Methylnitronitrosoguanidine
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4. Freeman HJ: Endoscopic excision of a prolapsing malignant polyp which caused intermittent gastric outlet obstruction. World J Gastroenterol; 2005 Sep 7;11(33):5245-7
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  • While prolapsing gastric antral polyps are usually benign and hyperplastic, inflammatory or regenerative in type, excisional snare polypectomy here led to complete resolution of his symptoms, but showed a malignant polyp.
  • [MeSH-minor] Aged. Carcinoma / pathology. Humans. Male

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  • (PMID = 16127764.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4320407
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5. Ohmiya N, Taguchi A, Mabuchi N, Itoh A, Hirooka Y, Niwa Y, Goto H: MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. J Clin Oncol; 2006 Sep 20;24(27):4434-40
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  • [Title] MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis.
  • The aim of this study was to determine whether SNP309 is associated with susceptibility to gastric carcinoma and its prognosis.
  • PATIENTS AND METHODS: In a case-control study including 438 controls and 410 patients with sporadic gastric carcinoma, MDM2 SNP309 was genotyped.
  • RESULTS: The risk of overall gastric carcinoma for SNP309 (G/G) was significantly increased when compared with T carriers (P = .039), especially carcinomas with extragastric tumors (P = .005), carcinoma with severe atrophic gastritis positive for PG assay (PG I level < 70 ng/mL and PG I/II < 3.0; P = .005), antral carcinoma (P = .020), intestinal-type carcinoma (P = .023), p53-immunopositive carcinoma (P = .007), and carcinoma with p53 mutations (P = .007).
  • SNP309 (G/G) was an independent marker of poor overall survival in advanced carcinoma (hazard ratio, 3.16; 95% CI, 1.22 to 8.20; P = .018).
  • [MeSH-major] Biomarkers, Tumor / genetics. Carcinoma / genetics. Polymorphism, Genetic. Proto-Oncogene Proteins c-mdm2 / genetics. Stomach Neoplasms / genetics

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  • (PMID = 16983111.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Genetic Markers; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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6. Umeda M, Minamikawa T, Komatsubara H, Ojima Y, Shibuya Y, Yokoo S, Komori T: En bloc resection of the primary tumour and cervical lymph nodes through the parapharyngeal space in patients with squamous cell carcinoma of the maxilla: a preliminary study. Br J Oral Maxillofac Surg; 2005 Feb;43(1):17-22
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  • [Title] En bloc resection of the primary tumour and cervical lymph nodes through the parapharyngeal space in patients with squamous cell carcinoma of the maxilla: a preliminary study.
  • We retrospectively studied 72 patients with maxillary carcinoma (48 of the gingiva, 22 of the antrum, and one each of the hard palate and maxillary bone).
  • The 5-year survival was 73% for those with gingival carcinoma, and 45% for those with antral carcinoma.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Maxillary Neoplasms / surgery. Maxillary Sinus Neoplasms / surgery. Neck Dissection / methods. Oral Surgical Procedures / methods

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  • (PMID = 15620769.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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7. Cai X, Carlson J, Stoicov C, Li H, Wang TC, Houghton J: Helicobacter felis eradication restores normal architecture and inhibits gastric cancer progression in C57BL/6 mice. Gastroenterology; 2005 Jun;128(7):1937-52
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  • Infected mice developed antral adenocarcinoma and gastric outlet obstruction by 24 months.
  • Only 30% of the mice receiving bacterial eradication therapy at 12 months developed antral carcinoma.

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  • (PMID = 15940628.001).
  • [ISSN] 0016-5085
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / K22 CA96485
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; F8VB5M810T / Tetracycline
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8. Sen N, Calli Demirkan N, Aksoy Altinboğa A, Bolat H, Erdem E: Synchronous endocrine tumors of small intestine: report of a case. Turk J Gastroenterol; 2008 Sep;19(3):193-6

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  • In addition, the whole antral portion of the Whipple resection material showed diffuse parietal cell hyperplasia.
  • The tumors were diagnosed as well-differentiated endocrine carcinoma in the ampulla of Vater according to the WHO classification 2000, a gastrin-producing well-differentiated endocrine tumor in the first portion of the duodenum without regional lymph node metastases, and a diffuse parietal cell hyperplasia at the antral portion of the stomach.

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  • (PMID = 19115157.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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9. Chiu CC, Wang W, Huang MT, Wei PL, Chen TC, Lee WJ: Palliative gastrojejunostomy for advanced gastric antral cancer: double scope technique. J Laparoendosc Adv Surg Tech A; 2006 Apr;16(2):133-6
MedlinePlus Health Information. consumer health - Stomach Cancer.

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  • [Title] Palliative gastrojejunostomy for advanced gastric antral cancer: double scope technique.
  • Gastrojejunostomy through laparotomy is a traditional procedure for the relief of gastric outlet obstruction in patients with unresectable carcinoma of the gastric antrum.
  • We present two cases of gastrojejunostomy for unresectable and obstructing gastric antral cancer using a double scope technique.
  • Palliative gastrojejunostomy via the double scope technique is a safe and effective minimally invasive procedure for the relief of gastric outlet obstruction in patients with unresectable carcinoma of the gastric antrum.

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  • (PMID = 16646703.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Thor PJ, Furgala A, Pach R, Hubalewska-Dydejczyk A, Mazur M, Matyja A, Kulig J, Huszno B: Antral gastric motility impairement and autonomic nervous system dysfunction in patients with pancreatic cancer (preliminary results). Folia Med Cracov; 2006;47(1-4):61-8
MedlinePlus Health Information. consumer health - Stomach Disorders.

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  • [Title] Antral gastric motility impairement and autonomic nervous system dysfunction in patients with pancreatic cancer (preliminary results).
  • The aim of the study was to evaluate the influence of pancreatic carcinoma on gastric motility and autonomic system activity in patients before surgery.
  • Antral distribution of meal suggests the presence of impaired proximal gastric response to meal due to diminished autonomic nervous system function and impaired myoelectric gastric activity in patients with pancreatic cancer.

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  • (PMID = 18038613.001).
  • [ISSN] 0015-5616
  • [Journal-full-title] Folia medica Cracoviensia
  • [ISO-abbreviation] Folia Med Cracov
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Pancreatic Hormones
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11. Samson JF, Suja V, Samad AK, George AE, Sankar S: Sinonasal carcinoma masquerading as fungal sinusitis. Indian J Dermatol Venereol Leprol; 2006 Nov-Dec;72(6):470
MedlinePlus Health Information. consumer health - Sinusitis.

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  • [Title] Sinonasal carcinoma masquerading as fungal sinusitis.
  • Based on a biopsy taken from the antral mass with special stain for fungus, he was treated as fungal sinusitis with intravenous amphotericin-B, but the lesion did not regress.
  • Later a skin biopsy from the indurated lesion showed moderately differentiated squamous cell carcinoma.
  • A diagnosis of sinonasal carcinoma was made and chemotherapy was started.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Mycoses. Nose Neoplasms / diagnosis. Paranasal Sinus Neoplasms / diagnosis. Sinusitis / diagnosis. Sinusitis / microbiology

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  • (PMID = 17186638.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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12. Murinello A, Damásio A, Figueiredo AM, Netta J, Carvalho A, Mato AA, Murillo MJ, Albuquerque A: Watermelon stomach, hemorrhagic pericarditis, small cell carcinoma of the lung and synchronous squamous cell carcinoma of the tongue base. Rev Port Pneumol; 2010 Jul-Aug;16(4):659-70
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  • [Title] Watermelon stomach, hemorrhagic pericarditis, small cell carcinoma of the lung and synchronous squamous cell carcinoma of the tongue base.
  • Based on a case of gastric antral vascular ectasia (watermelon stomach) that was associated with hemorrhagic pericarditis, small cell lung carcinoma with mediastinal lymph node metastases and a synchronous squamous cell carcinoma of the base of the tongue, the authors made a review of the clinical, endoscopic and histopathological aspects of this type of gastropathy, and its association with other diseases, and of the results of its endoscopic therapy.
  • To the best of our knowledge the association of watermelon stomach to small cell lung carcinoma and squamous cell carcinoma of the base of the tongue has not yet been described.
  • Extensive metastases to mediastal lymph nodes are common to small cell lung carcinoma.
  • [MeSH-major] Carcinoma, Squamous Cell / complications. Gastric Antral Vascular Ectasia / complications. Hemorrhage / complications. Lung Neoplasms / complications. Neoplasms, Multiple Primary / complications. Pericarditis / complications. Small Cell Lung Carcinoma / complications. Tongue Neoplasms / complications


13. Corso G, Pedrazzani C, Marrelli D, Pascale V, Pinto E, Roviello F: Correlation of microsatellite instability at multiple loci with long-term survival in advanced gastric carcinoma. Arch Surg; 2009 Aug;144(8):722-7
MedlinePlus Health Information. consumer health - Stomach Cancer.

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  • [Title] Correlation of microsatellite instability at multiple loci with long-term survival in advanced gastric carcinoma.
  • HYPOTHESIS: Microsatellite instability (MSI) correlates with clinicopathologic characteristics and long-term prognosis in patients having gastric carcinoma.
  • PATIENTS: Two hundred fifty patients with gastric carcinoma.
  • The MSI/5 phenotype was associated with older age (P < .001), female sex (P = .001), antral tumor location (P = .04), intestinal histotype (P = .003), and less infiltration of the serosa (P = .006); lymph node involvement was rare (P < .001) and was limited to few (median, 3) metastatic lymph nodes (P = .001).

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  • (PMID = 19687375.001).
  • [ISSN] 1538-3644
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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14. Karadag N, Kirimlioglu H, Isik B, Yilmaz S, Kirimlioglu V: Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis. Appl Immunohistochem Mol Morphol; 2008 Mar;16(2):148-52
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  • [Title] Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
  • The correlation between matrix metalloproteinase (MMP)-2, MMP-9, and MMP-14 expression on the prognostic parameters of gallbladder carcinoma (GBC) and their role in carcinogenesis were evaluated.
  • In contrast, MMP-9 and MMP-14 immunoreactivities were present in antral-type metaplastic areas as moderate (grade 2) and strong in dysplastic epithelia (grade 3).

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  • (PMID = 18227728.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9; EC 3.4.24.80 / Matrix Metalloproteinase 14
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15. Ueo T, Kashima K, Daa T, Kondo Y, Yokoyama S: Coexistence of Epstein-Barr virus-associated gastric carcinoma with malignant lymphoma: report of two cases. Virchows Arch; 2006 Aug;449(2):215-9
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  • [Title] Coexistence of Epstein-Barr virus-associated gastric carcinoma with malignant lymphoma: report of two cases.
  • Epstein-Barr virus (EBV)-associated gastric carcinoma (EBV-GC) is not rare, accounting for 5 to 18% of all gastric carcinomas.
  • The former was EBV-GC without lymphoma, and antral one was EBV-GC with diffuse large B-cell lymphoma (DLBCL).

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  • (PMID = 16609909.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Epstein-Barr virus encoded RNA 1; 0 / RNA, Viral
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16. Sachdeva S, Ghoshal UC, Saraswat VA, Das K, Misra A: Gastroduodenal dysmotility in patients with gallbladder carcinoma: frequency of occurrence and clinical importance. Natl Med J India; 2006 Jan-Feb;19(1):4-9
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  • [Title] Gastroduodenal dysmotility in patients with gallbladder carcinoma: frequency of occurrence and clinical importance.
  • BACKGROUND: Gastric stasis, common in patients with gall-bladder carcinoma (GBC), results from anatomical obstruction or motor abnormalities.
  • Patients with GBC had lower fasting (157 [68-284] v. 190.5 [150-284], p=0.01) and post-prandial (200 [96-395] v. 284 [178-395], p<0.0001) antral motor indices than healthy subjects.
  • [MeSH-major] Carcinoma / physiopathology. Duodenal Diseases / physiopathology. Gallbladder Neoplasms / physiopathology. Gastrointestinal Motility / physiology

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  • (PMID = 16570677.001).
  • [ISSN] 0970-258X
  • [Journal-full-title] The National medical journal of India
  • [ISO-abbreviation] Natl Med J India
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] India
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17. Hu KH, Tan CT, Lin KN, Cheng YJ, Huang HM: Effect of endoscopic sinus surgery on irradiation-induced rhinosinusitis in patients with nasopharyngeal carcinoma. Otolaryngol Head Neck Surg; 2008 Oct;139(4):575-9
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  • [Title] Effect of endoscopic sinus surgery on irradiation-induced rhinosinusitis in patients with nasopharyngeal carcinoma.
  • OBJECTIVES: We evaluated the effect of endoscopic sinus surgery on irradiation-induced rhinosinusitis of the maxillary-sinus mucosa among patients with nasopharyngeal carcinoma (NPC).
  • DESIGN: Surgical outcomes were evaluated by changes to the ultrastructure of the antral mucosa and nasomucociliary clearance.
  • RESULTS: In the postoperative cases, we found a decrease in the number of the submucosal gland openings (P < 0.05), the cilia in the antral mucosa regenerated (P < 0.05), and the saccharin transit time reduced (P < 0.05); the number of goblet cells did not change.

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  • (PMID = 18922347.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Kumar R: Microfilariae in lymph node aspirate associated with metastatic gastric carcinoma: a case report. Acta Cytol; 2010 May-Jun;54(3):319-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microfilariae in lymph node aspirate associated with metastatic gastric carcinoma: a case report.
  • A provisional diagnosis of gastric carcinoma with cirrhosis and ascites was made.
  • Biopsy of the antral mass confirmed the diagnosis of gastric carcinoma.
  • CONCLUSION: Detection of a microfilaria with malignant cells in the lymph node aspirates in a case of gastric carcinoma as an incidental finding is being reported for the first time.

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  • (PMID = 20518418.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Shirai K, Ohmiya N, Taguchi A, Mabuchi N, Yatsuya H, Itoh A, Hirooka Y, Niwa Y, Mori N, Goto H: Interleukin-8 gene polymorphism associated with susceptibility to non-cardia gastric carcinoma with microsatellite instability. J Gastroenterol Hepatol; 2006 Jul;21(7):1129-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Interleukin-8 gene polymorphism associated with susceptibility to non-cardia gastric carcinoma with microsatellite instability.
  • BACKGROUND AND AIM: Gastric carcinoma (GC) with microsatellite instability (MSI) exhibits clinicopathological characteristics distinct from microsatellite-stable (MSS) GC.
  • We found significant associations of MSI-H with synchronous or metachronous multiple occurrence, antral location and intestinal type.
  • [MeSH-major] Carcinoma / genetics. DNA, Neoplasm / genetics. Genetic Predisposition to Disease. Genomic Instability. Interleukin-8 / genetics. Polymorphism, Genetic. Stomach Neoplasms / genetics

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  • (PMID = 16824064.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Interleukin-8
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20. Zheng H, Takahashi H, Nakajima T, Murai Y, Cui Z, Nomoto K, Tsuneyama K, Takano Y: MUC6 down-regulation correlates with gastric carcinoma progression and a poor prognosis: an immunohistochemical study with tissue microarrays. J Cancer Res Clin Oncol; 2006 Dec;132(12):817-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MUC6 down-regulation correlates with gastric carcinoma progression and a poor prognosis: an immunohistochemical study with tissue microarrays.
  • PURPOSE: MUC6 was first discovered by screening a gastric mucosa cDNA library and is expressed in the mucous cells of the neck zone and antral glands of the stomach.
  • Kaplan-Meier analysis indicated that cumulative survival of patients with no MUC6 expression was significantly lower than with weak, moderate or strong expression in all and even advanced gastric carcinoma (P < 0.05).
  • CONCLUSIONS: Down-regulation of MUC6 may contribute to malignant transformation of gastric epithelial cells and underlie the molecular bases of growth, invasion, metastasis and differentiation of gastric carcinoma.
  • Altered expression might therefore be employed as an indicator of pathobiological behaviors and prognosis of gastric carcinoma.
  • [MeSH-major] Adenoma / metabolism. Carcinoma / metabolism. Gastric Mucosa / metabolism. Mucins / metabolism. Stomach Neoplasms / metabolism. Tissue Array Analysis / methods

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  • [Cites] Ann Surg Oncol. 2002 Nov;9(9):887-93 [12417511.001]
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  • (PMID = 16807756.001).
  • [ISSN] 0171-5216
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / MUC6 protein, human; 0 / Mucin-6; 0 / Mucins
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21. Cho YE, Kim JY, Kim YW, Park JH, Lee S: Expression and prognostic significance of human growth and transformation-dependent protein in gastric carcinoma and gastric adenoma. Hum Pathol; 2009 Jul;40(7):975-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression and prognostic significance of human growth and transformation-dependent protein in gastric carcinoma and gastric adenoma.
  • Human growth and transformation-dependent protein showed strong staining in the cytoplasm of intestinal-type adenocarcinoma and gastric adenoma, whereas normal gastric antral mucosa showed no staining.
  • These findings suggest that human growth and transformation-dependent protein expression is a common occurrence during the progression from a normal gastric mucosa to an intestinal-type carcinoma and may be associated with tumor cell proliferation activity.

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  • (PMID = 19269009.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / FAM162A protein, human; 0 / Ki-67 Antigen; 0 / Membrane Proteins; 0 / Mitochondrial Proteins
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22. Suriani R, Venturini I, Taraglio S, Mazzucco D, Grosso S, Predebon S, Mamo C, Tremosini S, Ballesini P, Borghi A, Zeneroli ML: Type III intestinal metaplasia, Helicobacter pylori infection and gastric carcinoma risk index in an Italian series of 1750 patients. Hepatogastroenterology; 2005 Jan-Feb;52(61):285-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Type III intestinal metaplasia, Helicobacter pylori infection and gastric carcinoma risk index in an Italian series of 1750 patients.
  • A positive correlation (p=0.000) between duodenal ulcer and Hp was found when antral Hp positivity was taken into account.
  • The gastric carcinoma risk index (GCRI) was found in 358 pts (20.4%); in this group 131 pts (36.6%) were Hp positive, 81 pts (22.65%) had IM-3 only in the antrum, 184 pts (51.4%) had atrophy.
  • Application of the GCRI might be useful for identifying a group of patients carrying a higher risk for gastric carcinoma.


23. Dickey A, Hrom J: A rare case of signet ring cell gastric adenocarcinoma. J Miss State Med Assoc; 2007 Sep;48(9):271-5
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient was found to have a large, obstructing antral mass that was biopsied by esophagogastroduodenoscopy (EGD) and revealed Signet Ring Cell gastric adenocarcinoma.
  • Gastric carcinoma frequently requires a multi-disciplinary approach to properly diagnose, stage, and treat.
  • [MeSH-major] Carcinoma, Signet Ring Cell / diagnosis. Gastric Bypass. Stomach Neoplasms / diagnosis

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  • (PMID = 19292116.001).
  • [ISSN] 0026-6396
  • [Journal-full-title] Journal of the Mississippi State Medical Association
  • [ISO-abbreviation] J Miss State Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Misra V, Misra SP, Dwivedi M, Singh PA: Giardia lamblia trophozoites in gastric biopsies. Indian J Pathol Microbiol; 2006 Oct;49(4):519-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To assess the prevalence of gastric giardiasis in gastric biopsies of patients with carcinoma stomach and in patients taking treatment for duodenal ulcer.
  • Gastric biopsy specimens from 54 patients of carcinoma stomach and 100 antral biopsies from patients taking treatment for duodenal ulcer were included in the study.
  • Eight out of 54 (14.9%) biopsies of gastric carcinoma patients harboured trophozoites of Giardia lamblia.
  • A careful search for G. lamblia trophozoites should be made while examining the gastric biopsies, especially in patients with carcinoma stomach, intestinal metaplasia, atrophic gastritis and those taking treatment for duodenal ulcer.
  • [MeSH-major] Carcinoma / parasitology. Duodenal Ulcer / drug therapy. Gastritis, Atrophic / parasitology. Giardia lamblia / isolation & purification. Giardiasis / epidemiology. Stomach Neoplasms / parasitology

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  • (PMID = 17183841.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Anti-Ulcer Agents
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25. Arotiba GT, Ladeinde AL, Oyeneyin JO, Nwawolo CC, Banjo AA, Ajayi OF: Malignant orofacial neoplasms in Lagos, Nigeria. East Afr Med J; 2006 Mar;83(3):62-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Squamous cell carcinoma (SCCA) with a peak age incidence in the 6th decade of life and a male to female ratio of 1.65 to 1 was the most common cancer (42.8%).
  • Patients who presented with antral SCCA were relatively younger (mean = 48.9 years) than those who had SCCA involving the mandibular gingiva/ alveolus (mean = 57.1 years) as well as floor of mouth (mean = 56.3 years).
  • Furthermore, males with antral SCCA were younger than their female counterparts.
  • Females who had antral GLDCA (mean = 32.4 years) were relatively younger than their male counterparts (mean = 49 years).
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Facial Neoplasms / physiopathology. Mouth Neoplasms / pathology

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  • [CommentIn] East Afr Med J. 2006 Mar;83(3):61 [16771100.001]
  • (PMID = 16771101.001).
  • [ISSN] 0012-835X
  • [Journal-full-title] East African medical journal
  • [ISO-abbreviation] East Afr Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Kenya
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26. Bakkelund K, Fossmark R, Nordrum IS, Waldum HL: Effect of antrectomy in hypergastrinaemic female Japanese cotton rats. Scand J Gastroenterol; 2009;44(1):32-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Antrectomy after 2 months of hypergastrinaemia prevented the development of carcinoma compared with in sham-operated animals, whereas some of the animals that were antrectomized at 2 months of age also developed carcinomas.
  • CONCLUSIONS: The removal of antral gastrin by antrectomy halts carcinogenesis in cotton rats, but other mechanisms may also play a role.
  • [MeSH-major] Carcinoma / prevention & control. Gastrectomy. Gastrins / metabolism. Hormones / metabolism. Pyloric Antrum / surgery. Stomach Neoplasms / prevention & control

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  • (PMID = 19037819.001).
  • [ISSN] 1502-7708
  • [Journal-full-title] Scandinavian journal of gastroenterology
  • [ISO-abbreviation] Scand. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Gastrins; 0 / Hormones
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27. Karam SM, Tomasetto C, Rio MC: Amplification and invasiveness of epithelial progenitors during gastric carcinogenesis in trefoil factor 1 knockout mice. Cell Prolif; 2008 Dec;41(6):923-935
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This study was designed to examine the changes that occur in pyloric antral mucous cell lineages and their progenitors during development of gastric adenoma and carcinoma in trefoil factor 1 (TFF1) knockout mice.
  • MATERIALS AND METHODS: Pyloric antral mucosal tissues of TFF1 knockout mice at ages from 3 days to 17 months were processed for histochemical analysis using Ulex europaeus and Grifforia simplifolica lectins as markers for pit and gland mucous cells, respectively.
  • Analysis of 12- to 17-month-old TFF1-deficient stomachs revealed occasional groups of poorly differentiated mucosal cells with features similar to those of epithelial progenitors (or stem cells), in the basal portion of the antral mucosa.

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  • (PMID = 19040570.001).
  • [ISSN] 1365-2184
  • [Journal-full-title] Cell proliferation
  • [ISO-abbreviation] Cell Prolif.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Lectins; 0 / Peptides; 0 / Tff1 protein, mouse; 0 / Trefoil Factor-1
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28. Lambertsen K, Bundgaard T: [Reconstruction of the maxilla with pedicled temporalis muscle after maxillectomy]. Ugeskr Laeger; 2009 Aug 17;171(34):2391-5
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  • Three patients developed oro-nasal/antral fistula, witch were later closed using local flaps.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / surgery. Follow-Up Studies. Humans. Middle Aged. Osteosarcoma / surgery. Quality of Life. Reoperation. Surveys and Questionnaires. Treatment Outcome. Young Adult

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  • (PMID = 19732522.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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29. Mukhopadhyay S, Landas SK: Putative precursors of gallbladder dysplasia: a review of 400 routinely resected specimens. Arch Pathol Lab Med; 2005 Mar;129(3):386-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: Dysplasia is thought to be a precursor of invasive gallbladder carcinoma, but it is unsettled whether dysplasia arises from other precursor lesions.
  • We retrospectively reviewed these cases to look for the presence of epithelial changes, including antral-type metaplasia, intestinal metaplasia, and dysplasia.
  • RESULTS: Antral-type metaplasia, intestinal metaplasia, and dysplasia were found in 238 (59.5%), 39 (9.8%), and 20 (5.0%) cases, respectively.
  • The mean ages for patients with antral-type metaplasia, intestinal metaplasia, and dysplasia were 49.4, 50.9, and 52.6 years, respectively.
  • Statistically significant associations were found between antral-type metaplasia and intestinal metaplasia (P = .007, chi2 test) and between intestinal metaplasia and dysplasia (P < .001, chi2 test).
  • CONCLUSION: These associations, along with the age gradient from antral-type metaplasia to dysplasia, suggest a progression from antral-type metaplasia to dysplasia via intestinal metaplasia.

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  • (PMID = 15737036.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Kitiyakara T, Selby W: Non-small-bowel lesions detected by capsule endoscopy in patients with obscure GI bleeding. Gastrointest Endosc; 2005 Aug;62(2):234-8
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  • RESULTS: Three patients had gastric antral vascular ectasia and another an inflamed pyloric canal polyp.
  • Two patients had actively bleeding cecal carcinoma, missed at previous colonoscopies.

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  • (PMID = 16046986.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Capsules
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31. Ionescu M, Dumitraşcu T, Stroescu C, Ciurea S, Popescu I: [Resection of the celiac axis increase resectability rate in locally advanced pancreatic body and gastric tumor]. Chirurgia (Bucur); 2006 May-Jun;101(3):297-305
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  • Carcinoma of the body and tail of the pancreas is often diagnosed at an advanced stage or metastatic stage.
  • Gastric carcinoma (particularly antral localization) can also be locally invasive.

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  • (PMID = 16927919.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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32. Lin DB, Lin JB, Chen CY, Chen SC, Chen WK: Seroprevalence of Helicobacter pylori infection among schoolchildren and teachers in Taiwan. Helicobacter; 2007 Jun;12(3):258-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Helicobacter pylori are associated with chronic antral gastritis that is related to duodenal ulcer, gastric ulcer, and probably gastric adenocarcinoma.
  • Infection of H. pylori during childhood is considered an important risk factor for gastric carcinoma in adult life.

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  • (PMID = 17493007.001).
  • [ISSN] 1083-4389
  • [Journal-full-title] Helicobacter
  • [ISO-abbreviation] Helicobacter
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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33. Bianchi LK, Burke CA, Bennett AE, Lopez R, Hasson H, Church JM: Fundic gland polyp dysplasia is common in familial adenomatous polyposis. Clin Gastroenterol Hepatol; 2008 Feb;6(2):180-5
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Gastric carcinoma arises from FGPs in FAP presumably from a dysplasia-carcinoma pathway.
  • Systematic biopsy specimens of FGPs, normal-appearing fundic mucosa, and antral mucosa for Helicobacter pylori were obtained.
  • In the multivariable analysis larger FGP size (odds ratio [OR], 4.0; 95% confidence interval [CI], 1.1-14.4), higher stage of duodenal polyposis (OR, 2.3; 95% CI, 1.2-4.5), and antral gastritis (OR, 11.2; 95% CI, 1.2-103.9) were associated with FGP dysplasia.
  • FGP dysplasia is associated with larger polyp size, increased severity of duodenal polyposis, and antral gastritis.

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  • (PMID = 18237868.001).
  • [ISSN] 1542-7714
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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34. Will U, Gerlach R, Wanzar I, Urban H, Manger T, Meyer F: Isolated vasculitis of the stomach: a novel or rare disease with a difficult differential diagnosis. Endoscopy; 2006 Aug;38(8):848-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report here the case of a 45-year-old woman with upper abdominal discomfort (no arthropathy), with gastroscopic and endoscopic ultrasound (EUS) findings that mimicked scirrhous gastric carcinoma.
  • Gastroscopy revealed giant gastric folds and a suspicious antral ulcer (with histological findings suggesting chronic active pangastritis).
  • On the basis of suspected scirrhous gastric carcinoma, the patient underwent a four-fifths gastric resection of the altered parts of the gastric tissue.
  • Gastric resection appears to be indicated in patients with isolated obliterative gastric vasculitis, since it avoids the side effects of long-term immunosuppressive therapy and provides prognostic information that takes account of the differential diagnosis of scirrhous gastric carcinoma.

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  • (PMID = 16673315.001).
  • [ISSN] 0013-726X
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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35. Mastracci L, Bruno S, Spaggiari P, Ceppa P, Fiocca R: The impact of biopsy number and site on the accuracy of intestinal metaplasia detection in the stomach A morphometric study based on virtual biopsies. Dig Liver Dis; 2008 Aug;40(8):632-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Intestinal metaplasia is a risk factor for gastric carcinoma.
  • We defined the extent of intestinal metaplasia on surgical specimens sampled by the "Swiss roll" technique and assessed the efficiency of an increasing number of "virtual" biopsies performed on the same rolls in recognising the true extent of intestinal metaplasia in the antro-angular region.
  • RESULTS: Seventy-four out of 455 cases showed intestinal metaplasia in more than 5% of the antro-angular mucosa.
  • The correlation between antro-angular intestinal metaplasia on rolls and on virtual biopsies was always highly significant, both when a single biopsy was considered and when groups of multiple biopsies (from 2 to 6 samples) were taken into account (p<or=0.0001 and rho ranging from 0.304 to 0.817).
  • The highest value of concordance between intestinal metaplasia extent in virtual biopsies and in rolls was recorded for a set of 4 antral+1 angular biopsies whereas a set of 2 antral+1 angular biopsies turned out to be the most effective in terms of number/efficacy.
  • CONCLUSIONS: A three biopsy set (2 antral+1 angular) allows correct detection of intestinal metaplasia extent in 90% of cases.

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  • (PMID = 18406219.001).
  • [ISSN] 1878-3562
  • [Journal-full-title] Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • [ISO-abbreviation] Dig Liver Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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36. Chan AW, Chan MW, Lee TL, Ng EK, Leung WK, Lau JY, Tong JH, Chan FK, To KF: Promoter hypermethylation of Death-associated protein-kinase gene associated with advance stage gastric cancer. Oncol Rep; 2005 May;13(5):937-41
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We aimed to investigate the frequency of gene promoter methylation of DAP-kinase in gastric carcinoma (GCA) and assessed its association with clinicopathological features.
  • One hundred and seven cases of gastric carcinoma were examined.
  • It also occurred in similar frequency among antral, body and cardiac gastric cancer.

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  • (PMID = 15809761.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / DNA Primers; 0 / DNA, Neoplasm; 0 / Genetic Markers; EC 2.7.11.1 / Death-Associated Protein Kinases; EC 2.7.11.17 / Calcium-Calmodulin-Dependent Protein Kinases
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37. Ma M, Chen J, Zhang YY, Li ZY, Jiang MZ, Yu JD: [Pathogenic effects of primary duodenogastric reflux on gastric mucosa of children]. Zhonghua Er Ke Za Zhi; 2008 Apr;46(4):257-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The increased entero-gastric reflux results in mucosal injury that may relate not only to reflux gastritis but also esophagitis, gastric ulcers, carcinoma of stomach and esophagus.
  • RESULT: The total fraction time of bile reflux in the patients with hyperemia and yellow stain gastric antral mucosa under endoscopy was significantly higher than that without those changes [17.1% (0.5% approximately 53.2%) vs. 6.5% (0 approximately 58.6%), Z = -1.980, P < 0.05; 19.8% (0.5% approximately 58.6%) vs. 8.8% (0 approximately 38.0%), Z = -2.956, P < 0.01 respectively].
  • CONCLUSION: Primary DGR could cause gastric mucosal lesions manifested mainly as hyperemia and bile-stained gastric antral mucosa under endoscopy and the gastric antral intestinal metaplasia histologically in children.

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  • (PMID = 19099725.001).
  • [ISSN] 0578-1310
  • [Journal-full-title] Zhonghua er ke za zhi = Chinese journal of pediatrics
  • [ISO-abbreviation] Zhonghua Er Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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38. Shaw JM, Bornman PC, Krige JE, Stupart DA, Panieri E: Self-expanding metal stents as an alternative to surgical bypass for malignant gastric outlet obstruction. Br J Surg; 2010 Jun;97(6):872-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Seventy patients underwent SEMS placement (hepatobiliary and pancreatic malignancy, 44; antral gastric carcinoma, 19; other, seven).

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  • (PMID = 20309895.001).
  • [ISSN] 1365-2168
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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39. Bahra M, Neumann U: Surgical techniques for resectable pancreatic cancer. Recent Results Cancer Res; 2008;177:29-38
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Due to both the aggressive biology of the disease and the late diagnosis in many cases, pancreatic duct carcinoma is still a disease with a poor prognosis.
  • Standard surgical strategies are the classic pancreaticoduodenectomy including a distal gastrectomy and the pylorus-preserving pancreaticoduodenectomy (PPPD) preserving antral and pyloric function, respectively.
  • Both surgical procedures are equally effective for the treatment of pancreatic carcinoma.

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  • (PMID = 18084944.001).
  • [ISSN] 0080-0015
  • [Journal-full-title] Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer
  • [ISO-abbreviation] Recent Results Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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40. Pizzolitto S, Camilot D, DeMaglio G, Falconieri G: Russell body gastritis: expanding the spectrum of Helicobacter pylori - related diseases? Pathol Res Pract; 2007;203(6):457-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a new case of Helicobacter pylori gastritis showing plasma cell infiltrates with extensive formation of Russell bodies (Mott cells) within the lamina propria of the antral mucosa.
  • Because of the accumulation of intracytoplasmic inclusions, Russell body gastritis is a potential source of diagnostic difficulties in endoscopic biopsy specimens that can be confused with immunocytic neoplasms, such as lymphoplasmacytic lymphoma or plasmocytoma, or signet-ring cell carcinoma.

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  • (PMID = 17395398.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD79; 0 / CD79A protein, human; 0 / Immunoglobulin kappa-Chains; 0 / Immunoglobulin lambda-Chains
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41. Whittle DO, Ewing R, Lee MG: The prevalence of Helicobacter pylori infection in patients undergoing upper gastrointestinal endoscopy in the Turks and Caicos Islands. West Indian Med J; 2010 Jun;59(3):309-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Antral gastritis was present in 13 patients, 7 (54%) were H pylori positive and 6 (46%) negative.
  • Distal oesophagitis was present in 5 patients (all negative for H pylori) and gastric carcinoma in 1 (H pylori positive).

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  • (PMID = 21291113.001).
  • [ISSN] 0043-3144
  • [Journal-full-title] The West Indian medical journal
  • [ISO-abbreviation] West Indian Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Jamaica
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42. Al-Dahmash BA, Marie MA: Helicobacter pylori-associated gastric pathological changes in Saudi patients. J Egypt Soc Parasitol; 2008 Apr;38(1):203-10
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The relation between Helicobacter pylori (H. pylori) and pathological changes in gastric mucosa ranging from active superficial gastritis to chronic active deep gastritis accompanied with intestinal metaplasia and dysplastic changes to gastric carcinoma of different grades.
  • At the same time a total of (10) patients with antral gastritis were used as control.
  • The findings suggested that gastric cancer may be induced in the disease associated with H. pylori in spite that the etiology of gastric carcinoma has not been clearly identified.

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  • (PMID = 19143131.001).
  • [ISSN] 1110-0583
  • [Journal-full-title] Journal of the Egyptian Society of Parasitology
  • [ISO-abbreviation] J Egypt Soc Parasitol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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43. Grynberg M, Fanchin R, Dubost G, Colau JC, Brémont-Weil C, Frydman R, Ayoubi JM: Histology of genital tract and breast tissue after long-term testosterone administration in a female-to-male transsexual population. Reprod Biomed Online; 2010 Apr;20(4):553-8
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  • Hence, many authors have assumed that androgen supplementation in women with poor ovarian reserve might improve the number of antral follicles available for ovarian stimulation.
  • Mean ovarian volume was increased, with histological characteristics of polycystic ovaries (PCO), defined as >12 antral follicles per ovary, observed in 89 patients (79.5%).
  • Breast examination revealed marked reduction of glandular tissue and increase of fibrous connective tissue in 93%, without atypical hyperplasia or carcinoma.

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  • [Copyright] Copyright (c) 2009 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20122869.001).
  • [ISSN] 1472-6491
  • [Journal-full-title] Reproductive biomedicine online
  • [ISO-abbreviation] Reprod. Biomed. Online
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Androgens; 3XMK78S47O / Testosterone
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44. Singhal AV, Sepulveda AR: Helicobacter heilmannii gastritis: a case study with review of literature. Am J Surg Pathol; 2005 Nov;29(11):1537-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The bacterium usually induces mild chronic gastritis but may be associated with peptic ulceration, and rare cases were reported in association with gastric carcinoma and mucosa-associated lymphoid tissue lymphoma.
  • Antral biopsy showed mild chronic gastritis with prominent lymphoid aggregates, and rare long, thin, spiral bacilli were present adjacent to the surface epithelium.

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  • (PMID = 16224223.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 28
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45. Singavarapu R, Buchinsky N, Cheon DJ, Orsulic S: Whole ovary immunohistochemistry for monitoring cell proliferation and ovulatory wound repair in the mouse. Reprod Biol Endocrinol; 2010;8:98
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Ovarian surface epithelial cells are thought to be a precursor cell type for ovarian carcinoma.
  • RESULTS: We determined that active proliferation of ovarian epithelial surface cells primarily occurs during antral follicle formation and, to a lesser extent, in response to an ovulatory wound.

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  • [Cites] Biol Reprod. 2001 Nov;65(5):1417-24 [11673258.001]
  • [Cites] Methods Mol Biol. 2008;461:687-95 [19030831.001]
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  • (PMID = 20712898.001).
  • [ISSN] 1477-7827
  • [Journal-full-title] Reproductive biology and endocrinology : RB&E
  • [ISO-abbreviation] Reprod. Biol. Endocrinol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Chorionic Gonadotropin; 0 / Gonadotropins, Equine; G34N38R2N1 / Bromodeoxyuridine
  • [Other-IDs] NLM/ PMC2929235
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46. Giuliani A, Demoro M, Corona M, Di Bari M, Ricciardulli T, Galati G, Ciardi A: Synchronous colon and gastric advanced carcinomas. J Exp Clin Cancer Res; 2005 Mar;24(1):155-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • An unusual case of advanced synchronous colon and gastric carcinoma is described.
  • At laparotomy, in addition to colon cancer, an antral gastric cancer was incidentally found.

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  • (PMID = 15943046.001).
  • [ISSN] 0392-9078
  • [Journal-full-title] Journal of experimental & clinical cancer research : CR
  • [ISO-abbreviation] J. Exp. Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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47. Schilling D, Spiethoff A, Rosenbaum A, Hartmann D, Eickhoff A, Jakobs R, Weickert U, Rebe M, Bohrer MH, Riemann JF: Does Cytokeratin7/20 immunoreactivity help to distinguish Barrett's esophagus from gastric intestinal metaplasia? Results of a prospective study of 75 patients. Pathol Res Pract; 2005;200(11-12):801-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Barrett's esophagus is a recognized risk factor for the development of esophageal dysplasia and carcinoma.
  • Cases of long segment Barrett's esophagus, short segment Barrett's esophagus, and cases with a normal gastroesophageal junction, as well as specimens with gastric antral intestninal metaplasia, were examined: three patterns were defined.
  • Seventy-five patients were enrolled in this study, 26 with long segment Barrett's esophagus, 21 with short segment esophagus, 13 with intestinal metaplasia of the cardia, and 18 with antral intestinal metaplasia.

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  • (PMID = 15792123.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Intermediate Filament Proteins; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 68238-35-7 / Keratins
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48. Akatsu Y, Saikawa Y, Kubota T, Kiyota T, Nakamura R, Akatsu T, Takahashi T, Yoshida M, Otani Y, Kumai K, Kitajima M: Metastatic gastric cancer from malignant fibrous histiocytoma: report of a case. Surg Today; 2006;36(4):385-9
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report the case of a 75-year-old man who underwent a distal gastrectomy for advanced gastric carcinoma, 2 years after resection of an MFH from the left side of his back.
  • We based our preliminary diagnosis of primary advanced gastric carcinoma on the results of a preoperative biopsy specimen, which suggested either poorly differentiated adenocarcinoma or nonepithelial cell-originating malignant disease-like lymphoma.
  • The resected stomach contained a large ulcerative tumor in the antral section, which was positive for Kp-1 and S-100 by immunohistochemical staining, confirming a pathological diagnosis of metastatic MFH of the stomach.


49. Marques T, David L, Reis C, Nogueira A: Topographic expression of MUC5AC and MUC6 in the gastric mucosa infected by Helicobacter pylori and in associated diseases. Pathol Res Pract; 2005;201(10):665-72
MedlinePlus Health Information. consumer health - Helicobacter Pylori Infections.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The immunoexpression of MUC5AC and MUC6 was evaluated in 75 adults presenting Helicobacter pylori gastritis (n = 22; 11 cagA positive), duodenal ulcer (DU, n = 11), gastric ulcer (GU, n = 9), gastric carcinoma (GC, n = 20), and normal mucosa (H. pylori negative, n = 13).
  • Five gastric areas (antral and corporeal lesser and greater curvatures and incisura) were studied. H. pylori was detected by carbolfuchsin, urease, and culture; cagA was determined by PCR.

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  • (PMID = 16325508.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, Bacterial; 0 / Bacterial Proteins; 0 / MUC5AC protein, human; 0 / MUC6 protein, human; 0 / Mucin 5AC; 0 / Mucin-6; 0 / Mucins; 0 / cagA protein, Helicobacter pylori; EC 3.5.1.5 / Urease
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50. Cabral MM, Oliveira CA, Mendes CM, Guerra J, Queiroz DM, Rocha GA, Rocha AM, Nogueira AM: Gastric epithelial cell proliferation and cagA status in Helicobacter pylori gastritis at different gastric sites. Scand J Gastroenterol; 2007 May;42(5):545-54
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  • OBJECTIVE: Helicobacter pylori infection causes hyperproliferation which is believed to predispose to the development of gastric carcinoma.
  • At the antral lesser curvature, PIs were higher than in all the other sites, both in H. pylori- (p<or=0.002) and cagA-positive groups (p<or=0.02).
  • CONCLUSIONS: We demonstrated that H. pylori infection and cagA-positive strains promote epithelial proliferation that was correlated with host inflammatory reaction and mostly at the antral lesser curvature, which is recognized as the area where most carcinomas arise.

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  • (PMID = 17454874.001).
  • [ISSN] 0036-5521
  • [Journal-full-title] Scandinavian journal of gastroenterology
  • [ISO-abbreviation] Scand. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Antibodies, Bacterial; 0 / Antigens, Bacterial; 0 / Bacterial Proteins; 0 / DNA, Bacterial; 0 / cagA protein, Helicobacter pylori
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51. Rabbani A: Experience with endoscopy at Bin Jalawi Hospital K.S.A. J Ayub Med Coll Abbottabad; 2005 Jan-Mar;17(1):37-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Antral Gastritis was most commonly seen pathology.
  • Gastric and esophageal varices, erosive gastritis, carcinoma oesophagus, duodenitis and oesophagitis were among the other common pathologies.

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  • (PMID = 15929525.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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52. Miyazaki T, Murayama Y, Shinomura Y, Yamamoto T, Watabe K, Tsutsui S, Kiyohara T, Tamura S, Hayashi N: E-cadherin gene promoter hypermethylation in H. pylori-induced enlarged fold gastritis. Helicobacter; 2007 Oct;12(5):523-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We have previously reported that the odds ratio for gastric carcinoma and the prevalence of diffuse-type early gastric carcinoma in Helicobacter pylori-induced enlarged fold gastritis increased with increasing fold width.
  • RESULTS: E-cadherin methylation percentage of the gastric antral and body mucosa in H. pylori-positive patients with enlarged folds was much greater than that in both H. pylori-positive and -negative patients without enlarged folds.
  • CONCLUSIONS: Our findings suggest that the hypermethylation of E-cadherin promoter might be involved in the process of gastric carcinoma through the specialized factors in H. pylori-induced enlarged fold gastritis.

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  • (PMID = 17760721.001).
  • [ISSN] 1083-4389
  • [Journal-full-title] Helicobacter
  • [ISO-abbreviation] Helicobacter
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cadherins
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53. El-Zimaity H: Gastritis and gastric atrophy. Curr Opin Gastroenterol; 2008 Nov;24(6):682-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RECENT FINDINGS: Key points to remember are: Helicobacter is associated with several forms of gastritis; in the present review, I am focusing on the two ends of the disease, 'Helicobacter pylori infection', that starts with antral predominant gastritis but can continue to oxyntic predominant disease with atrophy; the role Helicobacter pylori plays in autoimmune gastritis with pernicious anemia remains unresolved; gastritis staging systems for cancer risk, namely Baylor and Operative Link on Gastritis Assessment, are currently available.
  • SUMMARY: As most gastric carcinomas arise on a background of atrophic gastritis, and the risk increases with the extent of atrophy, an index of atrophy location and extent could be useful in predicting patients at greatest risk for carcinoma.

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  • (PMID = 19122515.001).
  • [ISSN] 1531-7056
  • [Journal-full-title] Current opinion in gastroenterology
  • [ISO-abbreviation] Curr. Opin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 50
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54. Gyorffy H: [Study of claudins and prognostic factors in some gastrointestinal diseases]. Magy Onkol; 2009 Dec;53(4):377-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • II. Gastric intestinal metaplasia showed higher expression of CLDN2, -3 and -4 as compared with normal antral foveolar mucosa.
  • [MeSH-minor] Adenocarcinoma / metabolism. Adolescent. Adult. Aged. Aged, 80 and over. Barrett Esophagus / metabolism. Carcinoma, Squamous Cell / metabolism. Child. Child, Preschool. Claudin-3. Female. Fluorescent Antibody Technique. Gastrointestinal Stromal Tumors / metabolism. Gene Expression Regulation, Neoplastic. Hemangiosarcoma / metabolism. Humans. Immunohistochemistry. Leiomyosarcoma / metabolism. Male. Membrane Proteins / metabolism. Middle Aged. Predictive Value of Tests. Prognosis. RNA, Messenger / metabolism. Risk Factors. Young Adult

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  • (PMID = 20071310.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CLDN3 protein, human; 0 / Claudin-3; 0 / Claudins; 0 / Membrane Proteins; 0 / RNA, Messenger
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55. Vlachostergios PJ, Voutsadakis IA, Barbanis S, Karasavvidou F, Papandreou CN: AFP-producing hepatoid adenocarcinoma of the stomach: a case report. Cases J; 2009;2:9296
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  • Hepatoid gastric adenocarcinoma is a distinct variant of gastric carcinoma which represents a comparatively small percentage of the disease and in many cases is producing high serum alpha-fetoprotein (AFP).
  • An endoscopic biopsy of the antral mass showed hepatoid variant of gastric adenocarcinoma.

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56. Liu H, Merrell DS, Semino-Mora C, Goldman M, Rahman A, Mog S, Dubois A: Diet synergistically affects helicobacter pylori-induced gastric carcinogenesis in nonhuman primates. Gastroenterology; 2009 Oct;137(4):1367-79.e1-6
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  • RESULTS: Postinoculation, H and EH groups showed persistent infection and antral gastritis.

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  • (PMID = 19622359.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA082312-08; United States / NCI NIH HHS / CA / R01 CA082312; United States / NCI NIH HHS / CA / R01 CA082312-08
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens; 12H3O2UGSF / Methylnitronitrosoguanidine; 4245-77-6 / ENNG
  • [Other-IDs] NLM/ NIHMS133423; NLM/ PMC2774828
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57. Shiotani A, Iishi H, Uedo N, Kumamoto M, Nakae Y, Ishiguro S, Tatsuta M, Graham DY: Histologic and serum risk markers for noncardia early gastric cancer. Int J Cancer; 2005 Jun 20;115(3):463-9
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  • Corpus dominant gastritis and intestinal metaplasia (IM) are considered markers of increased risk of gastric carcinoma.
  • Antral and corpus histology, pepsinogen and gastrin 17 levels were compared among patients with history of endoscopic mucosal resection (EMR) for early gastric cancer and controls.

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  • [Copyright] (c) 2005 Wiley-Liss, Inc.
  • (PMID = 15688378.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Gastrins; 60748-06-3 / gastrin 17; 61536-72-9 / Pepsinogen C; 9001-10-9 / Pepsinogen A
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58. Krueger S, Kalinski T, Hundertmark T, Wex T, Küster D, Peitz U, Ebert M, Nägler DK, Kellner U, Malfertheiner P, Naumann M, Röcken C, Roessner A: Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer. J Pathol; 2005 Sep;207(1):32-42
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  • Cathepsin X was predominantly expressed by macrophages in the mucosal stroma and in glands of the antral mucosa.
  • In addition, tumour cells stained for cathepsin X in 26 (68%) patients with gastric carcinoma.

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  • [Copyright] Copyright (c) 2005 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
  • (PMID = 16025436.001).
  • [ISSN] 0022-3417
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cytokines; 0 / RNA, Messenger; 0 / RNA, Neoplasm; EC 3.4.- / Cathepsins; EC 3.4.22.38 / CTSK protein, human; EC 3.4.22.38 / Cathepsin K
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59. Shi YL, Li LH, Sun ZH, Chen JY, Liao Y, Zeng LL, Zhang W, Chen XD, Cao C: [Study on the changing regularity of special antibody and expression of stomach and enteric involvement on SARS-coronavirus infection in the recovery period of severe acute respiratory syndrome]. Zhonghua Liu Xing Bing Xue Za Zhi; 2010 Jul;31(7):795-9
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  • The biopsy results of the 5 patients were as follows: 1 case diagnosed as "signet-ring cell carcinoma of the stomach and rectum multiple transfer", 1 case of gastric polyp, 1 case of superficial antral gastritis and 2 cases were normal.

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  • (PMID = 21162846.001).
  • [ISSN] 0254-6450
  • [Journal-full-title] Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
  • [ISO-abbreviation] Zhonghua Liu Xing Bing Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Viral; 0 / Immunoglobulin G; 0 / Immunoglobulin M; 0 / Nucleocapsid Proteins
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60. Mirzaee V, Molaei M, Shalmani HM, Zali MR: Helicobacter pylori infection and expression of DNA mismatch repair proteins. World J Gastroenterol; 2008 Nov 21;14(43):6717-21
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  • During endoscopy of patients with non-ulcer dyspepsia, two antral and two corpus biopsies were taken for histological examination (Giemsa stain) and for immunohistochemical staining of hMLH1 and hMSH2.
  • CONCLUSION: This study indicates that H pylori might promote development of gastric carcinoma at least in part through its ability to affect the DNA MMR system.

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  • (PMID = 19034977.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / MLH1 protein, human; 0 / MLH2 protein, human; 0 / Neoplasm Proteins; 0 / Nuclear Proteins
  • [Other-IDs] NLM/ PMC2773316
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