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1. Kwong RA, Kalish LH, Nguyen TV, Kench JG, Bova RJ, Cole IE, Musgrove EA, Sutherland RL: p14ARF protein expression is a predictor of both relapse and survival in squamous cell carcinoma of the anterior tongue. Clin Cancer Res; 2005 Jun 1;11(11):4107-16
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  • [Title] p14ARF protein expression is a predictor of both relapse and survival in squamous cell carcinoma of the anterior tongue.
  • PURPOSE: The INK4A-ARF locus at chromosome 9p21 is frequently altered in head and neck squamous cell carcinoma (SCC) and encodes two distinct tumor suppressors, p16(INK4A) and p14(ARF).
  • EXPERIMENTAL DESIGN: p14(ARF) protein expression was assessed by immunohistochemistry in a cohort of 140 patients with SCC of the anterior tongue.
  • RESULTS: On multivariate analysis, p14(ARF) positivity (nucleolar p14(ARF) staining and/or nuclear p14(ARF) staining in >/=30% of tumor cells) was an independent predictor of improved disease-free survival (DFS; P = 0.002) and overall survival (OS; P = 0.002).
  • CONCLUSIONS: These data show that in patients with SCC of the tongue, combined nuclear and nucleolar expression of p14(ARF) protein predicts for improved DFS and OS independent of established prognostic markers.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Tongue Neoplasms / pathology. Tumor Suppressor Protein p14ARF / biosynthesis
  • [MeSH-minor] Cell Cycle Proteins / analysis. Cohort Studies. Cyclin D1 / analysis. Cyclin-Dependent Kinase Inhibitor p16 / biosynthesis. Cyclin-Dependent Kinase Inhibitor p21. DNA-Binding Proteins / analysis. E2F Transcription Factors. E2F1 Transcription Factor. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Multivariate Analysis. Neoplasm Recurrence, Local. Neoplasm Staging. Predictive Value of Tests. Prognosis. Proportional Hazards Models. Retinoblastoma Protein / analysis. Survival Analysis. Transcription Factors / analysis. Tumor Suppressor Protein p53 / analysis

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  • (PMID = 15930346.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CDKN1A protein, human; 0 / Cell Cycle Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Cyclin-Dependent Kinase Inhibitor p21; 0 / DNA-Binding Proteins; 0 / E2F Transcription Factors; 0 / E2F1 Transcription Factor; 0 / E2F1 protein, human; 0 / Ki-67 Antigen; 0 / Retinoblastoma Protein; 0 / Transcription Factors; 0 / Tumor Suppressor Protein p14ARF; 0 / Tumor Suppressor Protein p53; 136601-57-5 / Cyclin D1
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2. Ozturk M, Mavili E, Erdogan N, Cagli S, Guney E: Tongue abscesses: MR imaging findings. AJNR Am J Neuroradiol; 2006 Jun-Jul;27(6):1300-3
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  • [Title] Tongue abscesses: MR imaging findings.
  • The objective of this study was to determine the MR imaging features of tongue abscesses.
  • METHODS: Seven surgically proved tongue abscesses were evaluated with MR imaging.
  • Four patients underwent MR imaging because of suspected tumor, and 3 patients, to show the extent and precise anatomic location of the lesion.
  • RESULTS: Five lesions were located in the anterior tongue and 2, in the posterior tongue.
  • The central parts of 4 anterior tongue abscesses were hypointense, surrounded by a hyperintense wall on T1-weighted precontrast images.
  • The smallest lesion located in the anterior tongue was hypointense on T1-weighted images and enhanced diffusely on postcontrast images.
  • Posterior tongue lesions appeared as polypoid ill-defined masses and were hypointense on T1-weighted images and heterogeneously hyperintense on T2-weighted images.
  • [MeSH-major] Abscess / diagnosis. Magnetic Resonance Imaging. Tongue Diseases / diagnosis
  • [MeSH-minor] Adult. Contrast Media. Female. Gadolinium DTPA. Humans. Male. Middle Aged. Tongue / pathology

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  • (PMID = 16775284.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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3. Smeets R, Grosjean MB, Heiland M, Riediger D, Maciejewski O: Distant metastases of a squamous cell carcinoma of the tongue in peripheral skeletal muscles and adjacent soft tissues. Head Face Med; 2008;4:7
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  • [Title] Distant metastases of a squamous cell carcinoma of the tongue in peripheral skeletal muscles and adjacent soft tissues.
  • A 66-year-old female patient was admitted to our department with a large tumor of the tongue measuring 10 cm in diameter.
  • The tumor occupied nearly the entire oral cavity and showed exophytic and ulcerative areas.
  • Histological analysis revealed a low grade squamous cell carcinoma (SCC) of the tongue.
  • The extent of the tumor infiltration was assessed by fluoro-2-deoxy-glucose-positron emission tomography (PET) scans showing an elevated activity of the tracer corresponding to the assumed cervical metastases.
  • Foci of distant metastases were found in the left upper anterior thoracal wall, near the intraabdominal portion of the aorta, near the right iliac crest and in both the right vastus medialis- and adductor magnus muscles.
  • The final diagnosis was a T4N3M1(G3)(C3) SCC of the tongue with multiple distant thoracal, abdominal and intramuscular metastases.
  • [MeSH-major] Carcinoma, Squamous Cell / secondary. Muscle Neoplasms / secondary. Tongue Neoplasms / pathology
  • [MeSH-minor] Aged. Female. Humans. Leg. Muscle, Skeletal. Neoplasm Staging

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  • (PMID = 18366774.001).
  • [ISSN] 1746-160X
  • [Journal-full-title] Head & face medicine
  • [ISO-abbreviation] Head Face Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2358884
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4. Uña E, Gandía F, Duque JL: Tongue paralysis after orotracheal intubation in a patient with primary mediastinal tumor: a case report. Cases J; 2009;2:9301

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tongue paralysis after orotracheal intubation in a patient with primary mediastinal tumor: a case report.
  • CASE PRESENTATION: We report here a case of bilateral hypoglossus palsy in a young man undergoing a diagnostic anterior mediastinotomy that was attributed to prolonged non-complicated oro-tracheal intubation.

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  • (PMID = 20062625.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2803965
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5. Enoz M, Suoglu Y, Ilhan R: Lingual schwannoma. J Cancer Res Ther; 2006 Apr-Jun;2(2):76-8
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  • Schwannomas or neurilemmomas are benign, slow growing, usually solitary and encapsulated tumor, originating from Schwann cells of the nerve sheath.
  • Intraoral schwannoma accounts for 1% of head and neck region and are commonly seen at the base region of tongue.
  • Most of the few such reports in the literature, have described schwannomas that occurred in the tongue.
  • In this article, we report a rare case of lingual schwannoma involving the anterior of tongue, in a young individual, in whom the lesion was completely excised via an intra oral approach.
  • [MeSH-major] Neurilemmoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 17998681.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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6. Schwartz DL, Hutcheson K, Barringer D, Tucker SL, Kies M, Holsinger FC, Ang KK, Morrison WH, Rosenthal DI, Garden AS, Dong L, Lewin JS: Candidate dosimetric predictors of long-term swallowing dysfunction after oropharyngeal intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys; 2010 Dec 1;78(5):1356-65
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  • Twenty-one (68%) cases were base of tongue and 10 (32%) were tonsil.
  • RESULTS: Dose-volume constraints (V30 < 65% and V35 < 35% for anterior oral cavity and V55 < 80% and V65 < 30% for high superior pharyngeal constrictors) predictive for objective swallowing dysfunction were identified by univariate and multivariate analyses.

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
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  • (PMID = 20646872.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672; United States / NCI NIH HHS / CA / R21 CA132281; United States / NCI NIH HHS / CA / CA132281
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS575664; NLM/ PMC4034521
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7. Lago-Méndez L, Blanco-Carrión A, Diniz-Freitas M, Gándara-Vila P, García-García A, Gándara-Rey JM: Rhomboid glossitis in atypical location: case report and differential diagnosis. Med Oral Patol Oral Cir Bucal; 2005 Mar-Apr;10(2):123-7
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  • [Title] Rhomboid glossitis in atypical location: case report and differential diagnosis.
  • Median rhomboid glossitis (MRG) is an uncommon benign abnormality of the tongue, most frequently affecting men.
  • It is typically located around the midline of the dorsum of the tongue, anterior to the lingual "V", appearing as a reddish, rhomboid area, depapillated, flat maculate or mamillated and raised by 2 - 5 mm.
  • This paper reports a case of rhomboid glossitis in a 61-year-old man who consulted for a painless raised lesion on the dorsum of the tongue, in left paramedial (not medial) location.
  • [MeSH-major] Glossitis / pathology. Tongue / pathology
  • [MeSH-minor] Amyloidosis / diagnosis. Antifungal Agents / therapeutic use. Candida albicans / isolation & purification. Candidiasis, Oral / diagnosis. Diagnosis, Differential. Granular Cell Tumor / diagnosis. Granuloma, Pyogenic / diagnosis. Hemangioma / diagnosis. Humans. Male. Middle Aged. Tongue Neoplasms / diagnosis

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  • (PMID = 15735544.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antifungal Agents
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8. Seckin D, Demirkesen C, Gurbuz O: Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue. J Am Acad Dermatol; 2008 Aug;59(2 Suppl 1):S23-4

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  • [Title] Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue.
  • Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue is a benign rare tumor.
  • It presents as a slowly growing, asymptomatic, submucosal nodule on the anterior dorsum of the tongue.
  • Histopathologically, the tumor is composed of a well-circumscribed, lobular proliferation of fusiform and ovoid cells in a chondromyxoid background.
  • Histogenetic origin of the tumor is uncertain.
  • We report here a 56-year-old woman with a 0.7-cm tumoral lesion of 5 months' duration on the anterior aspect of her tongue.
  • Total excision was performed and histopathologic findings were consistent with ectomesenchymal chondromyxoid tumor.
  • [MeSH-major] Mesenchymoma / pathology. Tongue / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 18625372.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Woo VL, Angiero F, Fantasia JE: Myoepithelioma of the tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 May;99(5):581-9
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  • [Title] Myoepithelioma of the tongue.
  • A histologically similar lesion that has a marked predilection for the anterior dorsum of the tongue has been referred to as ectomesenchymal chondromyxoid tumor.
  • We present a case of myoepithelioma of the tongue and review the literature, with emphasis on the differential diagnosis and histogenesis of this lesion and pertinent nosologic considerations.
  • [MeSH-major] Myoepithelioma / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Keratins / analysis. Membrane Proteins / analysis. S100 Proteins / analysis

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  • (PMID = 15829881.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CKAP4 protein, human; 0 / Membrane Proteins; 0 / S100 Proteins; 68238-35-7 / Keratins
  • [Number-of-references] 30
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10. Seo SH, Shin DH, Kang HJ, Choi KU, Kim JY, Park DY, Lee CH, Sol MY, Lee JC: Reticulated myxoid tumor of the tongue: 2 cases supporting an expanded clinical and immunophenotypic spectrum of ectomesenchymal chondromyxoid tumor of the tongue. Am J Dermatopathol; 2010 Oct;32(7):660-4

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  • [Title] Reticulated myxoid tumor of the tongue: 2 cases supporting an expanded clinical and immunophenotypic spectrum of ectomesenchymal chondromyxoid tumor of the tongue.
  • An ectomesenchymal chondromyxoid tumor (ECMT) is a rare neoplasm that exclusively occurs in the anterior dorsum of the tongue.
  • The tumor consists of small round to fusiform or spindle cells with myxoid or chondroid stroma.
  • The tumor consistently shows a positive reaction with glial fibrillary acidic protein antibodies, especially polyclonal antibodies.
  • We report 2 cases of reticulated myxoid tumors arising in the tongue.
  • One tumor occurred in the posterior dorsum of the tongue and another in the anterior.
  • [MeSH-major] Biomarkers, Tumor / analysis. Myxoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 20661118.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein
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11. Cirocco A, González F, Sáenz AM, Jiménez C, Sardi JR, Oscar RF: Embryonal rhabdomyosarcoma of the tongue. Pediatr Dermatol; 2005 May-Jun;22(3):218-21
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  • [Title] Embryonal rhabdomyosarcoma of the tongue.
  • We report a 10-month-old girl who, at 4 months, developed a small, reddish, plaquelike lesion on her tongue.
  • On physical examination, there was a large, red, friable, hard in consistency, irregular tumor over the distal portion of her tongue.
  • After the tumor size was reduced by chemotherapy, a partial anterior glossectomy was performed.
  • [MeSH-major] Rhabdomyosarcoma, Embryonal / pathology. Tongue Neoplasms / pathology

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  • (PMID = 15916568.001).
  • [ISSN] 0736-8046
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide
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12. Ko AB, Lavertu P, Rezaee RP: Double bilobed radial forearm free flap for anterior tongue and floor-of-mouth reconstruction. Ear Nose Throat J; 2010 Apr;89(4):177-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Double bilobed radial forearm free flap for anterior tongue and floor-of-mouth reconstruction.
  • We describe what is, to the best of our knowledge, the first use of a double bilobed radial forearm free flap in reconstructive surgery of the tongue and floor of the mouth following bilateral tumor resection.
  • Our patient was a 78-year-old man who had experienced tumor recurrence in the anterior floor of the mouth after previous resection and radiotherapy.
  • Eleven weeks postoperatively, the patient could extend his tongue to his hard palate and past his mandibular alveolus anteriorly.
  • Although the use of a single bilobed radial forearm flap is widely used after hemiglossectomy, our double bilobed modification extends this technique to anterior tongue and floor-of-mouth defects.
  • This technique provides adequate bulk while allowing for depth of a ventral sulcus that will minimize tethering of the tongue and reduce oral incompetence.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Mouth Floor / surgery. Neoplasm Recurrence, Local / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps. Tongue Neoplasms / surgery

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  • (PMID = 20397146.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Nakayama A, Miura H, Shindo Y, Kusakabe Y, Tomonari H, Harada S: Expression of the basal cell markers of taste buds in the anterior tongue and soft palate of the mouse embryo. J Comp Neurol; 2008 Jul 10;509(2):211-24
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  • [Title] Expression of the basal cell markers of taste buds in the anterior tongue and soft palate of the mouse embryo.
  • To examine the embryonic development of the basal cells, the expression of Shh, Prox1, and Mash1 was determined in the anterior tongue and soft palate in mouse embryos by in situ hybridization.
  • In the anterior tongue, Prox1 was coexpressed with Shh from the beginning of Shh expression in the fungiform papilla placodes at E12.5.
  • These results suggest that basal cell differentiation occurs synchronously with the patterning of Shh spots both in the anterior tongue and in the soft palate.
  • Furthermore, immunohistochemistry of PGP9.5 and Shh revealed that epithelial innervation slightly preceded Mash1 expression both in the tongue and in the soft palate.
  • [MeSH-major] Basic Helix-Loop-Helix Transcription Factors / biosynthesis. Gene Expression Regulation, Developmental. Hedgehog Proteins / biosynthesis. Homeodomain Proteins / biosynthesis. Palate, Soft / embryology. Taste Buds / embryology. Tongue / embryology. Tumor Suppressor Proteins / biosynthesis

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18465790.001).
  • [ISSN] 1096-9861
  • [Journal-full-title] The Journal of comparative neurology
  • [ISO-abbreviation] J. Comp. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ascl1 protein, mouse; 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / Biomarkers; 0 / Hedgehog Proteins; 0 / Homeodomain Proteins; 0 / Shh protein, mouse; 0 / Tumor Suppressor Proteins; 0 / prospero-related homeobox 1 protein
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14. Goveas N, Ethunandan M, Cowlishaw D, Flood TR: Ectomesenchymal chondromyxoid tumour of the tongue: Unlikely to originate from myoepithelial cells. Oral Oncol; 2006 Nov;42(10):1026-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectomesenchymal chondromyxoid tumour of the tongue: Unlikely to originate from myoepithelial cells.
  • Ectomesenchymal chondromyxoid tumour is a recently described rare entity found almost exclusively in the anterior dorsum of the tongue.
  • The lesion has no discriminating clinical features and diagnosis is only established following histopathological examination including immunohistochemical assessment.
  • [MeSH-major] Neoplasms, Connective Tissue / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Epithelial Cells / pathology. Female. Humans. Middle Aged. Neoplasm Proteins / metabolism

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  • (PMID = 17011812.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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15. Senoo H, Iida S, Kishino M, Namba N, Aikawa T, Kogo M: Solitary congenital granular cell lesion of the tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Jul;104(1):e45-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary congenital granular cell lesion of the tongue.
  • This lesion rarely occurs on the tongue, and only 7 cases, including 4 cases with simultaneous occurrence on the alveolar ridge, have been reported in the English literature.
  • In this report, we report a case of congenital granular cell lesion seen on the tongue.
  • The patient was a 7-day-old Japanese girl who presented with a polypoid mass on the anterior ventral surface near the tip of the tongue.
  • [MeSH-major] Gingival Neoplasms / pathology. Granular Cell Tumor / congenital. Tongue / abnormalities. Tongue Neoplasms / congenital

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  • (PMID = 17577543.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Raju B, Haug SR, Ibrahim SO, Heyeraas KJ: High interstitial fluid pressure in rat tongue cancer is related to increased lymph vessel area, tumor size, invasiveness and decreased body weight. J Oral Pathol Med; 2008 Mar;37(3):137-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High interstitial fluid pressure in rat tongue cancer is related to increased lymph vessel area, tumor size, invasiveness and decreased body weight.
  • Measurements of IFP in normal tongue and in tongue cancer are lacking.
  • MATERIALS AND METHODS: In the present study, tongue squamous cell carcinoma (SCC) was induced by adding the carcinogen 4-nitroquinoline oxide in drinking water for 19 weeks.
  • RESULTS: In normal tongue, IFP averaged 3.1 +/- 0.3 mmHg.
  • The IFP, both in the tumor (29.1 +/- 2.9 mmHg) and 0.5 cm anterior to it (15.4 +/- 2.1 mmHg) was consistently increased (P < 0.005) with values ranging from 10 to 40 mmHg.
  • There was a significant positive correlation between IFP, PTLV area, tumor size and invasiveness.
  • CONCLUSIONS: Our data show that IFP is increased in tongue cancer.
  • Corresponding changes in PTLV area, invasiveness, tumor area and IFP suggest that the increased pressure is caused by defective lymph drainage and solid stress generated by tumor cells growing in a low compliant environment.
  • [MeSH-major] Carcinoma, Squamous Cell / physiopathology. Extracellular Fluid / physiology. Lymphatic Vessels / pathology. Tongue Neoplasms / physiopathology
  • [MeSH-minor] 4-Nitroquinoline-1-oxide. Analysis of Variance. Animals. Body Weight. Male. Neoplasm Invasiveness. Pressure. Quinolones. Rats. Rats, Sprague-Dawley. Statistics, Nonparametric

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  • (PMID = 18251937.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / 4-nitroquinolone-1-oxide; 0 / Quinolones; 56-57-5 / 4-Nitroquinoline-1-oxide
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17. D'Cruz AK, Siddachari RC, Walvekar RR, Pantvaidya GH, Chaukar DA, Deshpande MS, Pai PS, Chaturvedi P: Elective neck dissection for the management of the N0 neck in early cancer of the oral tongue: need for a randomized controlled trial. Head Neck; 2009 May;31(5):618-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Elective neck dissection for the management of the N0 neck in early cancer of the oral tongue: need for a randomized controlled trial.
  • BACKGROUND: The aim of this study is to determine the need for a randomized controlled trial in order to define the role of an elective neck dissection (END) in the treatment of early tongue cancers.
  • METHODS: We present a large retrospective analysis of patients with T1-2 N0 squamous cell cancers of the oral anterior tongue treated at a single institution.
  • A total of 359 eligible patients with early tongue cancers were divided into 2 groups: END and wait and watch (WW).
  • Tumor grade and perineural invasion were independent predictors of recurrence.
  • [MeSH-major] Carcinoma, Squamous Cell / therapy. Elective Surgical Procedures. Neck Dissection. Tongue Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Decision Making. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Radiotherapy, Adjuvant. Randomized Controlled Trials as Topic. Retrospective Studies. Survival Analysis


18. Allen CM: The ectomesenchymal chondromyxoid tumor: a review. Oral Dis; 2008 Jul;14(5):390-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The ectomesenchymal chondromyxoid tumor: a review.
  • The ectomesenchymal chondromyxoid tumor is a relatively recently described neoplasm that appears to involve uniquely the oral cavity, particularly the tongue.
  • The size of the neoplasm is typically <2 cm, and most affect the anterior dorsal tongue.
  • Histopathologically, the ectomesenchymal chondromyxoid tumor is characterized by a well circumscribed, but unencapsulated, lobular growth pattern.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Male. Mesoderm / pathology. Middle Aged. Tongue Neoplasms / pathology. Tongue Neoplasms / therapy

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  • (PMID = 18593455.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 15
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19. Margaritescu C, Raica M, Pirici D, Simionescu C, Mogoanta L, Stinga AC, Stinga AS, Ribatti D: Podoplanin expression in tumor-free resection margins of oral squamous cell carcinomas: an immunohistochemical and fractal analysis study. Histol Histopathol; 2010 06;25(6):701-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Podoplanin expression in tumor-free resection margins of oral squamous cell carcinomas: an immunohistochemical and fractal analysis study.
  • The aim of this study was to establish podoplanin expression in the tumor-free resection margins of oral squamous cell carcinomas (OSCCs) and to evaluate the geometric complexity of the lymphatic vessels in oral mucosa by utilizing fractal analysis.
  • As concerns the podoplanin expression in noncancerous tissue, forty tumor-free resection margins from OSCCs were investigated utilizing immunohistochemistry for D2-40 antibody and image densitometry analysis.
  • However, a highly variable D2-40 expression in tumor-free resection margins associated with hyperplastic or dysplastic lesions was identified.
  • As concerns the study of the density and complexity of oral lymphatic vessels architecture by means of immunohistochemistry (D2-40, CD31 and Ki-67 antibodies) and fractal analysis, we demonstrated that in normal oral mucosa the geometry of the lymphatic vessels was less complex at the level of the lower lip compared to the anterior part of the oral floor mucosa or the tongue.
  • A comparative analysis between the normal and pathological aspects revealed statistically significant differences between the fractal dimension (FD) of the vessels' outline, especially in the tongue.
  • [MeSH-minor] Aged. Antibodies, Monoclonal / chemistry. Antibodies, Monoclonal / metabolism. Antibodies, Monoclonal, Murine-Derived. Biomarkers, Tumor / metabolism. Cell Nucleus / metabolism. Cell Nucleus / pathology. Female. Fluorescent Antibody Technique, Indirect. Fractals. Humans. Hyperplasia / metabolism. Hyperplasia / pathology. Image Processing, Computer-Assisted. Lip / pathology. Lymphatic Vessels / metabolism. Lymphatic Vessels / pathology. Male. Middle Aged. Mouth Mucosa / metabolism. Mouth Mucosa / pathology. Tongue / pathology

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  • (PMID = 20376776.001).
  • [ISSN] 1699-5848
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Biomarkers, Tumor; 0 / Membrane Glycoproteins; 0 / PDPN protein, human; 0 / monoclonal antibody D2-40
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20. Nigam S, Dhingra KK, Gulati A: Ectomesenchymal chondromyxoid tumor of the hard palate--a case report. J Oral Pathol Med; 2006 Feb;35(2):126-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectomesenchymal chondromyxoid tumor of the hard palate--a case report.
  • Ectomesenchymal chondromyxoid tumor (ECMT) is a rare tumor.
  • Only 26 cases of ECMT have been reported, all occurred in the anterior tongue.
  • The differential diagnosis considered included are extraskeletal myxoid chondroma, ECMT, pleomorphic adenoma, oral focal mucinosis, chondroid choristoma, and ossifying fibromyxoid tumor.
  • After serial sections no other component was observed and a diagnosis of ECMT was made by exclusion.
  • [MeSH-minor] Adenoma, Pleomorphic / pathology. Adult. Chondroma / pathology. Choristoma / pathology. Diagnosis, Differential. Fibroma, Ossifying / pathology. Follow-Up Studies. Humans. Male. Mouth Diseases / pathology. Mucinoses / pathology

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  • [CommentIn] J Oral Pathol Med. 2006 Sep;35(8):523-4; author reply 524 [16918608.001]
  • (PMID = 16430745.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 5
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21. Neo M, Asato R, Honda K, Kataoka K, Fujibayashi S, Nakamura T: Transmaxillary and transmandibular approach to a C1 chordoma. Spine (Phila Pa 1976); 2007 Apr 1;32(7):E236-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A 19-year-old man presented with a large ossified retropharyngeal chordoma (6 cm in diameter) originating from the right side of the anterior arch of C1, and extending from the clivus to the C2/3 intervertebral disc level in the sagittal plane.
  • Ten days after the fusion, the tumor was resected using a mandible and tongue midsplitting approach combined with a Le Fort I (transmaxillary) osteotomy, which allowed us to expose the entire tumor.
  • The tumor was hard and immovable because of ossification.
  • The main part of the tumor was resected from the anterior arch of C1, and then the C1 anterior arch was resected en bloc.
  • This enabled us to resect totally the tumor into 2 pieces without major complications or sequelae.
  • [MeSH-minor] Adult. Humans. Male. Osteotomy / methods. Spinal Fusion / methods. Tongue / surgery. Treatment Outcome


22. Sun J, Weng Y, Li J, Wang G, Zhang Z: Analysis of determinants on speech function after glossectomy. J Oral Maxillofac Surg; 2007 Oct;65(10):1944-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: To determine which of the following factors-type of reconstruction, size of tumor, and site of excision-may influence speech intelligibility after glossectomy.
  • MATERIALS AND METHODS: The speech intelligibilities of 27 tongue cancer patients who underwent glossectomy within the range of the hemitongue were investigated within 6 months after operation with a speech intelligibility test formed by 100 sensitive Chinese sounds.
  • They were compared according to the following factors: type of reconstruction (forearm flap or adjacent flap); size of tumor (T1, T2, T3); and site of excision (anterior, middle, posterior, or hemi part).
  • The speech intelligibilities of the patients with tumors in anterior tongue or hemitongue were significantly lower than those with tumor in the middle or posterior tongue (P < .05).
  • Patients with preservation of the tip of the tongue or floor of the mouth had higher intelligibilities (P < .05).
  • CONCLUSION: For the patients after glossectomy within the range of hemitongue, except for the type of reconstruction, the tumor site or excision extent of the tongue followed by the tumor size may be key factors in determining the postoperative articulation intelligibility.
  • [MeSH-major] Articulation Disorders / etiology. Glossectomy / adverse effects. Reconstructive Surgical Procedures / adverse effects. Speech Intelligibility. Tongue Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Surgical Flaps / adverse effects. Tongue / surgery

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  • (PMID = 17884520.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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23. Bozkaya S, Uğar D, Karaca I, Ceylan A, Uslu S, Bariş E, Tokman B: The treatment of lymphangioma in the buccal mucosa by radiofrequency ablation: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Nov;102(5):e28-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lymphangioma is a benign, hamartomatous tumor of the lymphatic system.
  • When lymphangioma occurs in the mouth, the anterior two thirds of the tongue is the most commonly affected region.

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  • (PMID = 17052620.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Alharbi FA, Lenarz T, Stoever T: A case of unilateral hypoglossus nerve palsy associated with chordoma in the region of clivus. Eur Arch Otorhinolaryngol; 2009 Dec;266(12):2001-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A computed tomography (CT) scan of the skull base showed bone destruction at the anterior part of the foramen magnum and CT scan of the neck reveals asymmetrical area at the base of the tongue.
  • The tumor was biopsied through transnasal biopsy from the region of the clivus using a navigation system and microscopical surgical technique.
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Middle Aged. Neurosurgical Procedures / methods. Tomography, X-Ray Computed

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  • [Cites] Neurosurgery. 1995 May;36(5):887-96; discussion 896-7 [7791978.001]
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  • (PMID = 19590882.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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25. Firat Y, Aygenç E, Firat AK, Oto A, Selçuk A, Firat MM, Ozdem C: Computed tomography virtual laryngoscopy: comparison between radiological and otolaryngological evaluations for laryngeal carcinoma. Kulak Burun Bogaz Ihtis Derg; 2006;16(3):97-104
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Lesions localized in the base of the tongue, pyriform sinus, aryepiglottic folds, and arytenoids were well visualized by both RTV and CTVL.
  • The two techniques were not found effective in identifying lesions of the ventricular bands, ventricular cavities, and the anterior commissure.
  • CONCLUSION: Virtual laryngoscopy is a noninvasive and reliable technique that provides visualization of endolaryngeal surfaces and tumor extension.
  • [MeSH-minor] Adult. Aged. Female. Humans. Image Processing, Computer-Assisted / methods. Male. Middle Aged. Neoplasm Invasiveness. Predictive Value of Tests. Sensitivity and Specificity

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  • (PMID = 16763426.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Turkey
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26. Zeina AR, Nachtigal A, Avshovich N, Rosner I, Rozenbaum M: Hypoglossal nerve palsy secondary to cervical spine involvement in rheumatoid arthritis: clinical and radiological features. Joint Bone Spine; 2009 Oct;76(5):547-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report herein an uncommon case of isolated HN palsy secondary to RA cervical spine involvement: pannus formation at the C1-C2 articulation, atlanto-axial subluxation, as well as, erosion of the right occipital condyle, lateral mass and anterior arch of C1.
  • We also present the variety of diagnostic modalities helpful for the diagnosis and follow-up.
  • [MeSH-minor] Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Antirheumatic Agents / therapeutic use. Dysarthria / etiology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed. Tongue Diseases / etiology. Tumor Necrosis Factor-alpha / antagonists & inhibitors. Tumor Necrosis Factor-alpha / immunology


27. Saito T, Watanabe Y, Yuzawa M, Saito T, Tamemoto H, Suzuki H, Kusaka G, Omori Y, Shinoda S, Kawakami M, Ishikawa SE: SIADH is only an atypical clinical feature in a patient with prolactinoma. Intern Med; 2007;46(10):653-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • He had neither dry skin or tongue, nor pretibial edema.
  • Serum prolactin was 254 ng/ml, and anterior pituitary hormones of ACTH, TSH and GH were in the normal ranges.
  • Brain magnetic resonance imaging (MRI) showed a pituitary tumor with a size of 20 x 22 x 21 mm and it pushed a pituitary stalk upward.

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  • (PMID = 17527038.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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28. Fournier HD, Hue AS, Laccourreye L: [Extensive lower clivus chordomas. Removal using the unilateral transmandibular approach]. Neurochirurgie; 2008 Apr;54(2):63-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • If the tumor remains extradural for a while, it finally progresses through the dura backwards to reach and displace the brain stem and upper cervical cord.
  • Its anterior extension in the retropharyngeal space offers a logical opportunity and many advantages to use an anterior approach.
  • Tracheostomy is needed because of a transient tongue oedema.
  • RESULTS: The unilateral transmandibular approach enabled to anatomical and physiological nasal preservation, large operative field facilitating dural closure and tumor removal, with acceptable cosmetic results and sequellae considering the natural course and prognosis of the tumor.

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  • (PMID = 18359050.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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29. Kakarala K, Faquin WC, Deschler DG: A comparison of histopathologic margin assessment after steel scalpel, monopolar electrosurgery, and ultrasonic scalpel glossectomy in a rat model. Laryngoscope; 2010;120 Suppl 4:S155

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: Histopathologic margin assessment is important in guiding treatment and determining prognosis for squamous cell cancer of the oral tongue.
  • METHODS: The anterior tongue of thirty Sprague-Dawley rats was excised using either steel scalpel, monopolar electrosurgery, or ultrasonic scalpel (three groups of ten).
  • CONCLUSIONS: Energy based devices cause tissue distortion which may in theory effect the ability to accurately assess surgical margins for tumor involvement on histopathology.
  • [MeSH-minor] Analysis of Variance. Animals. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Disease Models, Animal. Hemostasis, Surgical. Male. Rats. Rats, Sprague-Dawley. Steel. Surgical Instruments. Tongue Neoplasms / pathology. Tongue Neoplasms / surgery

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  • (PMID = 21225753.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 12597-69-2 / Steel
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30. Just T, Stave J, Bombor I, Kreutzer HJ, Guthoff R, Pau HW: [In vivo diagnosis of epithelial changes of the oropharynx using confocal microscopy]. Laryngorhinootologie; 2008 Mar;87(3):174-80
MedlinePlus Health Information. consumer health - Oral Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [In vivo diagnosis of epithelial changes of the oropharynx using confocal microscopy].
  • BACKGROUND: Confocal laser scanning microscopy enables the visualization of the anterior regions of the oropharynx mucosa.
  • The investigations were performed on 9 patients with tongue cancer with primary tumor site and stage I (AJCC) and on 12 patients with head and neck cancer who underwent radiochemotherapy (RCT).
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Cell Transformation, Neoplastic / pathology. Leukoplakia, Oral / diagnosis. Microscopy, Confocal. Mouth Neoplasms / diagnosis. Neoplasm Recurrence, Local / diagnosis. Otorhinolaryngologic Neoplasms / diagnosis. Precancerous Conditions / diagnosis. Tongue Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Combined Modality Therapy. Epithelium / pathology. Follow-Up Studies. Humans. Mouth Floor / pathology. Mouth Mucosa / pathology. Neoplasm Staging. Sensitivity and Specificity

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  • (PMID = 17963192.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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31. Dabaja B, Salehpour MR, Rosen I, Tung S, Morrison WH, Ang KK, Garden AS: Intensity-modulated radiation therapy (IMRT) of cancers of the head and neck: comparison of split-field and whole-field techniques. Int J Radiat Oncol Biol Phys; 2005 Nov 15;63(4):1000-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • IMRT is delivered to the primary tumor and upper neck alone, while the lower neck is treated with a matching anterior beam.
  • WF-IMRT has an advantage if uncertainty at the match line is a concern, whereas HB-IMRT, particularly in cases not involving the base of tongue, can achieve much lower doses to the larynx.

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  • (PMID = 15978743.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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32. Jabbour SA, Davidovici BB, Wolf R: Rare syndromes. Clin Dermatol; 2006 Jul-Aug;24(4):299-316
MedlinePlus Health Information. consumer health - Endocrine Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The syndrome also includes mucosal neuromas, typically involving the lips and tongue, intestinal ganglioneuromas and a marfanoid habitus.
  • Multiple endocrine neoplasia type 1 is an autosomal dominant predisposition to tumors of the parathyroid glands (four-gland hyperplasia), anterior pituitary, and pancreatic islet cells; hence, the mnemonic device of the "3 Ps"; multiple cutaneous lesions (angiofibromas and collagenomas) are frequent in patients with multiple endocrine neoplasia type 1.
  • Additional unusual manifestations include psammomatous melanotic schwannoma, breast ductal adenoma, and a rare bone tumor, osteochondromyxoma.

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  • (PMID = 16828412.001).
  • [ISSN] 0738-081X
  • [Journal-full-title] Clinics in dermatology
  • [ISO-abbreviation] Clin. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 155
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33. Zhang B, Li DZ, Xu ZG, Tang PZ: Deep inferior epigastric artery perforator free flaps in head and neck reconstruction. Oral Oncol; 2009 Feb;45(2):116-20
MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A retrospective review was performed of 12 patients with head and neck tumor ablation defects that were reconstructed with the deep inferior epigastric artery perforator (DIEAP) free flaps between January 2004 and December 2006.
  • Recipient sites were subdivided into defects of total or subtotal glossectomy (N=6), three-dimensional defects of midface (N=3), through and through defects of the cheek (N=2), and anterior skull base resection with an external skin component defect (N=1).The overall free flap success rate was 92% (11/12).
  • [MeSH-minor] Abdominal Wall / blood supply. Adult. Aged. Humans. Male. Middle Aged. Rectus Abdominis / surgery. Retrospective Studies. Tongue Neoplasms / surgery

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  • (PMID = 18621569.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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34. Nakamura T, Kodaira T, Tachibana H, Tomita N, Yokouchi J, Fuwa N: Clinical outcome of oropharyngeal carcinoma treated with platinum-based chemoradiotherapy. Oral Oncol; 2009 Sep;45(9):830-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nine patients who had a tumor in the base of the tongue were also treated with arterial infusion chemotherapy.
  • The 5-year local control rate for each subsite was: anterior wall, 90%; lateral wall, 80%; posterior wall, 67%; and superior wall, 64%.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carboplatin / administration & dosage. Cisplatin / administration & dosage. Combined Modality Therapy / methods. Disease-Free Survival. Feasibility Studies. Female. Fluorouracil / administration & dosage. Humans. Japan. Male. Middle Aged. Neoplasm Recurrence, Local. Organoplatinum Compounds / administration & dosage. Radiotherapy Dosage. Retrospective Studies. Treatment Outcome

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  • (PMID = 19457713.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; 8UQ3W6JXAN / nedaplatin; BG3F62OND5 / Carboplatin; Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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35. Yagi S, Nakayama B, Kamei Y, Takahashi M, Torii S: Posterolateral cervical vein as a recipient vein in reconstructive microvascular surgery of the head and neck. J Reconstr Microsurg; 2007 Jan;23(1):19-23
MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, many patients who have undergone radiotherapy and radical neck dissection or who require treatment for recurrent tumor, often present difficulty in choosing recipient vessels.
  • The authors have noted a potential recipient vein coursing vertically along the anterior ridge of the trapezius muscle.
  • [MeSH-minor] Aged. Carcinoma, Squamous Cell / surgery. Glossectomy. Humans. Male. Mandibular Neoplasms / surgery. Muscle, Skeletal / transplantation. Neck Dissection. Skin Transplantation / methods. Subclavian Vein / anatomy & histology. Tongue Neoplasms / surgery. Veins / surgery

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  • (PMID = 17230316.001).
  • [ISSN] 0743-684X
  • [Journal-full-title] Journal of reconstructive microsurgery
  • [ISO-abbreviation] J Reconstr Microsurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Li B, Li CH, Guo H, Chen J, Wang SX: [Analysis of 27 cases of defect restoration using infrahyoid myocutaneous flap after intraoral cancer surgery]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Nov;43(11):826-9
MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Seven cases of squamous cell tongue carcinoma, 4 cases of tongue root carcinoma, 16 cases of mouth floor carcinoma.
  • Eleven cases of the reservation vascularized and infrahyoid muscles in the hyoid attachment (combination pedicle), in 16 cases, the arteria and vena thyroidea superior reserved as the pedicle accompanied with the vena jugularis anterior (the axial vessel pedicle); in 21 cases, the distal end of the vena jugularis interna was tied up at the place where the vena facialis communis joins to the vena jugularis interna. and the vena jugularis anterior was reserved within the flap (interference return).
  • The primary tumor recurrence in three cases, six cases of cervical lymph node recurrence, Kaplan-Meier method statistics 3, 5-year survival rates were 69.8%, 47.2%, respectively.

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  • (PMID = 19267973.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] China
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