[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 222
1. Myerson RJ, Garofalo MC, El Naqa I, Abrams RA, Apte A, Bosch WR, Das P, Gunderson LL, Hong TS, Kim JJ, Willett CG, Kachnic LA: Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas. Int J Radiat Oncol Biol Phys; 2009 Jul 1;74(3):824-30
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas.
  • RESULTS: The panel achieved consensus CTV definitions to be used as guidelines for the adjuvant therapy of rectal cancer and definitive therapy for anal cancer.
  • The most important difference from similar atlases for gynecologic or genitourinary cancer is mesorectal coverage.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Jun 1;53(2):497-503 [12023155.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Jan 1;52(1):176-83 [11777636.001]
  • [Cites] IEEE Trans Med Imaging. 2004 Jul;23(7):903-21 [15250643.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Nov 1;60(3):794-806 [15465196.001]
  • [Cites] N Engl J Med. 2004 Oct 21;351(17):1731-40 [15496622.001]
  • [Cites] Biometrics. 1977 Mar;33(1):159-74 [843571.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1986 Sep;12(9):1565-73 [3759581.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Jul 1;35(4):745-9 [8690640.001]
  • [Cites] J Clin Oncol. 1996 Sep;14(9):2527-39 [8823332.001]
  • [Cites] Cancer Radiother. 2004 Oct;8(5):297-304 [15561595.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2005 Sep 1;63(1):274-81 [16111597.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2005 Oct 1;63(2):354-61 [16168830.001]
  • [Cites] JAMA. 2005 Nov 23;294(20):2587-93 [16304072.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):907-16 [16751073.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1129-42 [16750329.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Oct 1;66(2):505-13 [16879928.001]
  • [Cites] N Engl J Med. 2006 Sep 14;355(11):1114-23 [16971718.001]
  • [Cites] Cancer J Sci Am. 1996 Jul-Aug;2(4):205-11 [9166533.001]
  • [Cites] J Clin Oncol. 2006 Oct 1;24(28):4620-5 [17008704.001]
  • [Cites] Int J Colorectal Dis. 2007 Apr;22(4):373-9 [16802067.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2007 Apr 1;67(5):1389-93 [17394942.001]
  • [Cites] J Clin Oncol. 2007 Oct 10;25(29):4581-6 [17925552.001]
  • [Cites] Acta Oncol. 2007;46(7):937-44 [17851844.001]
  • [Cites] Semin Radiat Oncol. 2003 Oct;13(4):433-40 [14586832.001]
  • (PMID = 19117696.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] ENG
  • [Grant] None / None / / U10 CA021661-30; United States / NCI NIH HHS / CA / U10 CA32115; United States / NCI NIH HHS / CA / U24 CA081647; United States / NCI NIH HHS / CA / U10 CA21661; United States / NCI NIH HHS / CA / U10 CA021661-30; United States / NCI NIH HHS / CA / U10 CA37422; United States / NCI NIH HHS / CA / U24 CA81647; United States / NCI NIH HHS / CA / U10 CA037422; United States / NCI NIH HHS / CA / U10 CA021661; United States / NCI NIH HHS / CA / U10 CA032115
  • [Publication-type] Consensus Development Conference; Journal Article; Practice Guideline; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Number-of-references] 30
  • [Other-IDs] NLM/ NIHMS121642; NLM/ PMC2709288
  •  go-up   go-down


2. Zachariah B, Gwede CK, James J, Ajani J, Chin LJ, Donath D, Rosenthal SA, Kane BL, Rotman M, Berk L, Kachnic LA: Octreotide acetate in prevention of chemoradiation-induced diarrhea in anorectal cancer: randomized RTOG trial 0315. J Natl Cancer Inst; 2010 Apr 21;102(8):547-56
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Octreotide acetate in prevention of chemoradiation-induced diarrhea in anorectal cancer: randomized RTOG trial 0315.
  • BACKGROUND: In anorectal cancer patients, an acute side effect of chemoradiotherapy is gastrointestinal toxicity, which often impedes treatment delivery.
  • METHODS: A randomized, double-blinded, placebo-controlled trial was designed to determine the efficacy of long-acting octreotide acetate (LAO) in preventing the onset of acute diarrhea in patients undergoing chemoradiation therapy for rectal or anal cancer.

  • Genetic Alliance. consumer health - Diarrhea.
  • MedlinePlus Health Information. consumer health - Diarrhea.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Natl Cancer Inst. 2000 Mar 1;92(5):388-96 [10699069.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2012 Mar 15;82(4):1367-75 [21775070.001]
  • [Cites] Urology. 2000 Dec 20;56(6):899-905 [11113727.001]
  • [Cites] J Clin Oncol. 2002 Jan 15;20(2):557-66 [11786586.001]
  • [Cites] J Clin Oncol. 2002 Apr 1;20(7):1744-50 [11919230.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Sep 1;54(1):195-202 [12182992.001]
  • [Cites] J Clin Oncol. 2004 Jul 15;22(14):2918-26 [15254061.001]
  • [Cites] Support Care Cancer. 2004 Aug;12(8):561-70 [15160318.001]
  • [Cites] Eur J Cancer Care (Engl). 2004 Sep;13(4):380-3 [15305907.001]
  • [Cites] N Engl J Med. 2004 Oct 21;351(17):1731-40 [15496622.001]
  • [Cites] J Chronic Dis. 1974 Sep;27(7-8):365-75 [4612056.001]
  • [Cites] Scand J Gastroenterol. 1978;13(4):481-3 [675160.001]
  • [Cites] Dig Dis Sci. 1982 May;27(5):459-66 [6122550.001]
  • [Cites] Am J Surg. 1984 Jan;147(1):43-8 [6691550.001]
  • [Cites] Dis Colon Rectum. 1987 May;30(5):324-33 [3568920.001]
  • [Cites] Int J Colorectal Dis. 1986 Oct;1(4):251-5 [3598321.001]
  • [Cites] Gastroenterol Clin North Am. 1989 Dec;18(4):897-922 [2559036.001]
  • [Cites] J Clin Oncol. 1993 Jan;11(1):148-51 [8418225.001]
  • [Cites] Anticancer Drugs. 1993 Aug;4(4):443-5 [8400346.001]
  • [Cites] Oncology. 1994 Jan-Feb;51(1):70-3 [8265106.001]
  • [Cites] Ann Surg. 1994 Nov;220(5):676-82 [7979617.001]
  • [Cites] Qual Life Res. 1994 Aug;3(4):267-72 [7812279.001]
  • [Cites] J Clin Oncol. 1996 Sep;14(9):2527-39 [8823332.001]
  • [Cites] Dis Colon Rectum. 1997 May;40(5):515-22 [9152176.001]
  • [Cites] J Clin Oncol. 1997 May;15(5):2040-9 [9164216.001]
  • [Cites] Dis Colon Rectum. 1998 May;41(5):543-9; discussion 549-51 [9593234.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1998 Jun 1;41(3):593-8 [9635707.001]
  • [Cites] J Clin Oncol. 1998 Sep;16(9):3169-78 [9738589.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1998 Sep 1;42(2):257-61 [9788402.001]
  • [Cites] Ann Surg Oncol. 1999 Jul-Aug;6(5):433-41 [10458680.001]
  • [Cites] Clin Colorectal Cancer. 2005 Jan;4(5):302-12 [15663833.001]
  • [Cites] Dis Colon Rectum. 2005 Jul;48(7):1343-9; discussion 1349-52; author reply 1352 [15933797.001]
  • [Cites] Clin Chim Acta. 2005 Sep;359(1-2):1-26 [15936746.001]
  • [Cites] Am J Clin Oncol. 2006 Apr;29(2):132-7 [16601430.001]
  • [Cites] J Support Oncol. 2006 Jun;4(6):289-94 [16805331.001]
  • [Cites] Anticancer Res. 2006 May-Jun;26(3B):2325-8 [16821610.001]
  • [Cites] J Clin Oncol. 2007 Apr 1;25(10):1255-9 [17401014.001]
  • [Cites] JAMA. 2008 Apr 23;299(16):1914-21 [18430910.001]
  • [Cites] J Clin Oncol. 2008 Nov 10;26(32):5248-53 [18768432.001]
  • [Cites] J Clin Oncol. 2000 Mar;18(6):1239-45 [10715293.001]
  • (PMID = 20339140.001).
  • [ISSN] 1460-2105
  • [Journal-full-title] Journal of the National Cancer Institute
  • [ISO-abbreviation] J. Natl. Cancer Inst.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / U10 CA21661; United States / NCI NIH HHS / CA / U10 CA32115; United States / NCI NIH HHS / CA / U10 CA37422
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antidiarrheals; 0 / Antineoplastic Agents; RWM8CCW8GP / Octreotide
  • [Other-IDs] NLM/ PMC2857801
  •  go-up   go-down


3. Khaniya S, Koirala R, Shakya VC, Adhikary S, Regmi R, Pandey SR, Agrawal CS: Anorectal tuberculosis coexisting with adenocarcinoma: an unusual association. Cases J; 2009;2:143

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal tuberculosis coexisting with adenocarcinoma: an unusual association.
  • INTRODUCTION: Tuberculosis affecting the anorectum is an uncommon extra-pulmonary form of the disease, and its association with malignancy is highly unusual.
  • With the diagnosis of carcinoma lower rectum, she underwent abdomino-perineal resection of the growth.
  • CONCLUSION: The aetiological association between the tuberculosis and anorectal cancer is a matter of debate.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Colorectal Dis. 2008 Oct;10(8):846-7 [18294272.001]
  • [Cites] Am Surg. 1953 Feb;19(2):121-7 [13016948.001]
  • [Cites] Dis Colon Rectum. 1986 Nov;29(11):738-41 [3769689.001]
  • (PMID = 19292907.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


Advertisement
4. Alter BP, Giri N, Savage SA, Rosenberg PS: Cancer in dyskeratosis congenita. Blood; 2009 Jun 25;113(26):6549-57
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cancer in dyskeratosis congenita.
  • The spectrum of cancer susceptibility in this disorder of telomere biology has not been described.
  • There were more than 500 cases of DC reported in the literature from 1910 to 2008; the National Cancer Institute (NCI) prospective DC cohort enrolled 50 cases from 2002 to 2007.
  • The 2 cohorts were comparable in their median overall survival (42 years) and cumulative incidence of cancer (40%-50% by age 50 years).
  • The most frequent solid tumors were head and neck squamous cell carcinomas (40% of patients in either cohort), followed by skin and anorectal cancer.
  • Significantly elevated O/E ratios were 1154 for tongue cancer and 195 for acute myeloid leukemia.
  • The frequency and types of cancer in DC are surpassed only by those in Fanconi anemia (FA), indicating that FA and DC have similarly high risks of adverse hematologic and neoplastic events, and patients with these diseases should be counseled and monitored similarly.

  • Genetic Alliance. consumer health - Dyskeratosis congenita.
  • Genetics Home Reference. consumer health - dyskeratosis congenita.
  • MedlinePlus Health Information. consumer health - Cancer in Children.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Blood. 2007 Mar 1;109(5):2256-62 [17038525.001]
  • [Cites] Br J Oral Maxillofac Surg. 2007 Mar;45(2):156-8 [16024141.001]
  • [Cites] Br J Haematol. 2007 Sep;138(6):815-7 [17760812.001]
  • [Cites] Hematology Am Soc Hematol Educ Program. 2007;:29-39 [18024606.001]
  • [Cites] Am J Hum Genet. 2008 Feb;82(2):501-9 [18252230.001]
  • [Cites] Mech Ageing Dev. 2008 Jan-Feb;129(1-2):35-47 [18160098.001]
  • [Cites] Haematologica. 2008 Apr;93(4):511-7 [18322251.001]
  • [Cites] Pediatr Dev Pathol. 2008 Mar-Apr;11(2):148-51 [17990901.001]
  • [Cites] Blood. 2008 Nov 1;112(9):3594-600 [18669893.001]
  • [Cites] Hematol Oncol Clin North Am. 2009 Apr;23(2):215-31 [19327580.001]
  • [Cites] Blood. 2007 Sep 1;110(5):1439-47 [17468339.001]
  • [Cites] Br J Oral Surg. 1971 Jul;9(1):8-20 [4106452.001]
  • [Cites] Przegl Dermatol. 1974 Sep-Oct;61(5):687-91 [4421637.001]
  • [Cites] Dermatologica. 1975;151(5):316-8 [1225670.001]
  • [Cites] Pediatrics. 1981 Jan;67(1):128-35 [7243421.001]
  • [Cites] Br J Dermatol. 1981 Sep;105(3):321-5 [7272212.001]
  • [Cites] Rinsho Ketsueki. 1982 Aug;23(8):1222-7 [7143726.001]
  • [Cites] Hautarzt. 1983 Jun;34(6):286-7 [6874335.001]
  • [Cites] Med Cutan Ibero Lat Am. 1982;10(6):365-8 [6764238.001]
  • [Cites] Scand J Haematol. 1984 May;32(5):461-8 [6539499.001]
  • [Cites] Arch Dermatol. 1984 Oct;120(10):1381-2 [6486855.001]
  • [Cites] Wiad Lek. 1988 Apr 15;41(8):525-30 [3239051.001]
  • [Cites] Zhonghua Yi Xue Za Zhi (Taipei). 1989 Jan;43(1):57-62 [2475234.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1990;417(3):247-53 [2166977.001]
  • [Cites] Blood. 1992 Jun 15;79(12):3138-44 [1596563.001]
  • [Cites] Blood. 1992 Dec 15;80(12):3090-6 [1361371.001]
  • [Cites] J Laryngol Otol. 1992 Nov;106(11):996-7 [1479281.001]
  • [Cites] Ann Dent. 1994 Summer;53(1):15-8 [8060104.001]
  • [Cites] Presse Med. 1995 Jun 17;24(22):1047 [7667234.001]
  • [Cites] Biometrics. 1995 Sep;51(3):874-87 [7548706.001]
  • [Cites] Br J Haematol. 1996 Mar;92(3):758-65 [8616050.001]
  • [Cites] Dig Dis Sci. 1996 Dec;41(12):2340-2 [9011439.001]
  • [Cites] Arch Dermatol. 1997 Jan;133(1):97-8, 101 [9006380.001]
  • [Cites] Am J Hum Genet. 1997 Mar;60(3):581-7 [9042917.001]
  • [Cites] Pediatr Radiol. 1997 Mar;27(3):286 [9126597.001]
  • [Cites] Acta Clin Belg. 1998 Jun;53(3):198-202 [9701856.001]
  • [Cites] Br J Haematol. 1998 Oct;103(1):243-8 [9792316.001]
  • [Cites] AMA Arch Derm. 1957 Dec;76(6):712-9 [13478161.001]
  • [Cites] AMA Arch Derm. 1958 Jun;77(6):704-12 [13544605.001]
  • [Cites] Am J Otolaryngol. 1999 Nov-Dec;20(6):405-7 [10609487.001]
  • [Cites] J Eur Acad Dermatol Venereol. 2000 Mar;14(2):123-5 [10972098.001]
  • [Cites] Br J Haematol. 2000 Sep;110(4):768-79 [11054058.001]
  • [Cites] Genet Couns. 2001;12(2):129-36 [11491307.001]
  • [Cites] Nature. 2001 Sep 27;413(6854):432-5 [11574891.001]
  • [Cites] Cancer. 2003 Jan 15;97(2):425-40 [12518367.001]
  • [Cites] Blood. 2003 Feb 1;101(3):822-6 [12393424.001]
  • [Cites] J Eur Acad Dermatol Venereol. 2003 Mar;17(2):216-8 [12705757.001]
  • [Cites] Oral Oncol. 2004 Aug;40(7):758-9 [15172647.001]
  • [Cites] Blood. 2004 Jul 15;104(2):350-5 [15059844.001]
  • [Cites] Med Welt. 1966 Nov 26;48:2589-94 [5979458.001]
  • [Cites] Przegl Dermatol. 1970 Mar-Apr;57(2):239-42 [5423544.001]
  • [Cites] Med J Aust. 1965 May 29;1(22):797-9 [14312691.001]
  • [Cites] Arch Dermatol. 1963 Sep;88:340-7 [14043629.001]
  • [Cites] Blood. 2005 Jan 1;105(1):67-73 [15331448.001]
  • [Cites] Blood. 2005 Jan 15;105(2):682-8 [15238429.001]
  • [Cites] Pediatr Dermatol. 2005 Jan-Feb;22(1):31-5 [15660894.001]
  • [Cites] Br J Haematol. 2005 May;129(3):432-4 [15842668.001]
  • [Cites] Bone Marrow Transplant. 2005 Dec;36(12):1103-5; author reply 1105 [16205731.001]
  • [Cites] Blood. 2006 Apr 1;107(7):2680-5 [16332973.001]
  • [Cites] Blood. 2006 Jun 15;107(12):4628-35 [16497969.001]
  • [Cites] Semin Hematol. 2006 Jul;43(3):157-66 [16822458.001]
  • [Cites] Blood Cells Mol Dis. 2006 Sep-Oct;37(2):134-6 [16934504.001]
  • [Cites] Br J Dermatol. 2007 Feb;156(2):406-8 [17223904.001]
  • [CommentIn] Blood. 2009 Jun 25;113(26):6502-3 [19556430.001]
  • (PMID = 19282459.001).
  • [ISSN] 1528-0020
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Review
  • [Publication-country] United States
  • [Number-of-references] 70
  • [Other-IDs] NLM/ PMC2710915
  •  go-up   go-down


5. Daniel WJ: Anorectal pain, bleeding and lumps. Aust Fam Physician; 2010 Jun;39(6):376-81
MedlinePlus Health Information. consumer health - Rectal Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal pain, bleeding and lumps.
  • BACKGROUND: The patient presenting with anal pain, anal lump or rectal bleeding is a common occurrence in the general practice setting and the combination of symptoms usually gives an indication of the most likely diagnosis.
  • OBJECTIVE: This article discusses three common anorectal conditions: perianal haematoma, haemorrhoids and anal fissure, and briefly discusses the less common, but not to be missed conditions: anal carcinoma and low rectal carcinoma.
  • Anal cancer has similar presentation to haemorrhoids and carcinoma of distal rectum can initially present with a haemorrhoid, so the possibility of anorectal cancer should be considered in any patient presenting with haemorrhoids, tenesmus and change in bowel habit.
  • [MeSH-major] Pain / diagnosis. Rectal Diseases / physiopathology
  • [MeSH-minor] Diagnosis, Differential. Hemorrhage / etiology. Humans

  • MedlinePlus Health Information. consumer health - Pain.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20628675.001).
  • [ISSN] 0300-8495
  • [Journal-full-title] Australian family physician
  • [ISO-abbreviation] Aust Fam Physician
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


6. Higashi D, Futami K, Kawahara K, Kamitani T, Seki K, Naritomi K, Egawa Y, Hirano K, Tamura T, Tomiyasu T, Ishibashi Y, Simomura T, Nii K, Kinugasa T: Study of colorectal cancer with Crohn's disease. Anticancer Res; 2007 Nov-Dec;27(6A):3771-4
MedlinePlus Health Information. consumer health - Crohn's Disease.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Study of colorectal cancer with Crohn's disease.
  • In addition, in Japan, more cases with concomitant malignant disease have also recently been reported.
  • There is a particularly high risk of cancer occurring simultaneously in the lower rectum and the anal area.
  • We studied malignant diseases concomitant with CD, based on empirical examples.
  • RESULTS: Thirteen (4.5%) were cases concomitant with malignant disease: six patients had colorectal cancer, 1 had rectal carcinoid, 1 had stomach cancer, 1 had uterine cancer, 1 had thyroid cancer, 1 had skin cancer and 2 had acute leukemia.
  • Regarding the seven cases other than colorectal cancer, they were all juvenile patients under the age of 50, except for the stomach cancer case (69 years of age).
  • Among the 6 cases of colorectal cancer, 5 cases were anorectal cancer and 1 was lower rectal cancer.
  • The average age was 42.8 years (30-54 years) and the average term from CD occurrence to cancer diagnosis was 208 months (69-387 months).
  • The one case with lower rectal cancer was intramucosal cancer which did not recur after surgery.
  • The five cases of anorectal cancer were advanced, with invasion of the adjacent organs and 2 of them were unresectable.
  • Four cases were of the infiltrative type, and regarding the histological findings, 4 cases were cancer with mucous production and 1 case was a poorly-differentiated endocrine tumor.
  • CONCLUSION: In Japan, prolonged CD cases have been increasing and more and more cases of malignant disease with concomitant CD have been reported.
  • There is a particularly high risk of cancer occurring simultaneously in the lower rectum and the anal area.
  • Therefore, careful observation, taking all appropriate diagnostic surveillance modalities into consideration, is thus believed to be important in order to achieve an early detection of such cancer.


7. Lian P, Gu WL, Zhang Z, Cai GX, Wang MH, Xu Y, Sheng WQ, Cai SJ: Retrospective analysis of perianal Paget's disease with underlying anorectal carcinoma. World J Gastroenterol; 2010 Jun 21;16(23):2943-8
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Retrospective analysis of perianal Paget's disease with underlying anorectal carcinoma.
  • METHODS: PPD patients were retrospectively collected in the institutional colorectal database of the Fudan University Shanghai Cancer Center.
  • Detailed patient histories of past medical condition, diagnosis, treatment, and pathological findings were reviewed.
  • Surgical specimen from diagnosis and surgery were reviewed by two independent pathologists for confirmation of diagnoses.
  • All patients had underlying anorectal adenocarcinoma, including seven with synchronous lesions and one with metachronous lesions.
  • Moreover, all anorectal lesions had a mucin-producing component.
  • The median age at diagnosis was 65 (range 29-81 years), and the male/female ratio was 7:1.
  • Underlying anorectal cancer was not unusual and was a significant prognostic factor.
  • Rational treatment of both anorectal cancer and PPD lesion is essential for long-term survival.
  • [MeSH-major] Anus Neoplasms / diagnosis. Paget Disease, Extramammary / diagnosis. Rectal Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Acta Pathol Jpn. 1991 May;41(5):386-93 [1651042.001]
  • [Cites] Changgeng Yi Xue Za Zhi. 1990 Dec;13(4):314-21 [2178040.001]
  • [Cites] Dis Colon Rectum. 1996 Feb;39(2):227-31 [8620793.001]
  • [Cites] Ann Surg Oncol. 1997 Sep;4(6):475-80 [9309336.001]
  • [Cites] Am J Surg Pathol. 1998 Feb;22(2):170-9 [9500217.001]
  • [Cites] Cancer. 1963 Mar;16:387-403 [13953662.001]
  • [Cites] Med Sci Monit. 2007 Jun;13(6):CS75-7 [17534239.001]
  • [Cites] Dis Colon Rectum. 1997 Oct;40(10):1187-94 [9336114.001]
  • [Cites] Dis Colon Rectum. 2000 Apr;43(4):499-502 [10789745.001]
  • [Cites] Dis Colon Rectum. 2001 Jun;44(6):868-70 [11391150.001]
  • [Cites] J Cutan Pathol. 2002 Mar;29(3):185-9 [11972718.001]
  • [Cites] Clin Oncol (R Coll Radiol). 2002 Aug;14(4):272-84 [12206637.001]
  • [Cites] Dis Colon Rectum. 2003 May;46(5):612-6 [12792436.001]
  • [Cites] Dis Colon Rectum. 2003 Nov;46(11):1563-5 [14605581.001]
  • [Cites] Colorectal Dis. 2004 May;6(3):206-9 [15109389.001]
  • [Cites] Acta Gastroenterol Belg. 2004 Apr-Jun;67(2):228-31 [15285581.001]
  • [Cites] Dis Colon Rectum. 1973 Jan-Feb;16(1):46-55 [4347585.001]
  • [Cites] Dis Colon Rectum. 1976 Jan-Feb;19(1):30-40 [174872.001]
  • [Cites] Arch Dermatol. 1979 Jun;115(6):706-8 [222218.001]
  • [Cites] Am J Dermatopathol. 1979 Summer;1(2):101-32 [232972.001]
  • [Cites] Tumori. 1984 Aug 31;70(4):381-3 [6089390.001]
  • [Cites] Arch Dermatol. 1985 Jun;121(6):750-2 [2408584.001]
  • [Cites] Arch Dermatol. 1987 Mar;123(3):379-82 [3028283.001]
  • [Cites] Dis Colon Rectum. 1987 Apr;30(4):263-6 [3030676.001]
  • [Cites] J Surg Oncol. 1988 May;38(1):38-44 [2836660.001]
  • [Cites] Dis Colon Rectum. 1988 Jun;31(6):462-6 [2837369.001]
  • [Cites] Br J Surg. 1989 Jan;76(1):60-3 [2537129.001]
  • [Cites] Dis Colon Rectum. 1990 Feb;33(2):150-2 [2153511.001]
  • [Cites] Am J Gastroenterol. 1990 Feb;85(2):199-202 [2154090.001]
  • [Cites] Dis Colon Rectum. 1990 Jun;33(6):502-7 [2161727.001]
  • [Cites] Int J Colorectal Dis. 1992 Sep;7(3):167-9 [1328429.001]
  • (PMID = 20556842.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2887592
  •  go-up   go-down


8. O'Lorcain P, Deady S, Comber H: Mortality predictions for colon and anorectal cancer for Ireland, 2003-17. Colorectal Dis; 2006 Jun;8(5):393-401
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mortality predictions for colon and anorectal cancer for Ireland, 2003-17.
  • OBJECTIVE: Colorectal cancer mortality predictions for Ireland are presented for all ages and for the age group 0-64 years.
  • METHODS: Log and log-linear Poisson regression modelling was fitted to colorectal cancer mortality data for each year between 1950 and 2002 to predict average European age standardized mortality rates (EASMRs) per 100,000 person years (100,000 PY(-1)) and average numbers of deaths.
  • RESULTS: EASMRs for colon cancer are predicted to fall to 17.3 100,000 PY(-1) (95%PI 14.4, 20.2) in men and to 8.4 100,000 PY(-1) (95%PI 6.9, 10.2) in women by 2013-17.
  • EASMRs for anorectal cancer are also predicted to fall to 8.0 100,000 PY(-1) (95%PI 6.6, 9.5) in men and to 3.0 100,000 PY(-1) (95%PI 2.3, 3.8) in women by this time.
  • Truncated EASMRs for colon cancer for those aged between 0 and 64 years are predicted over the next 15 years to fall from their current levels to 4.4 100,000 PY(-1) (95%PI 3.0, 5.8) in men and to 2.3 100,000 PY(-1) (95%PI 1.5, 3.2) in women.
  • For anorectal cancer, truncated EASMRs for those aged between 0 and 64 years are also predicted over the next 15 years to fall from their current levels to 2.9 100,000 PY(-1) (95%PI 2.0, 3.8) in men and to 0.9 100,000 PY(-1) (95%PI 0.4, 1.3) in women.

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16684083.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


9. Stern DR, Steinhagen RM: Anorectal cancer following topical formalin application for haemorrhagic radiation proctitis. Colorectal Dis; 2007 Mar;9(3):275-8
Hazardous Substances Data Bank. FORMALDEHYDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal cancer following topical formalin application for haemorrhagic radiation proctitis.
  • In the course of reviewing our experience with this modality, we identified two patients who developed anorectal cancer during the follow-up period.
  • METHOD: From 2001 to 2005, 49 patients who received pelvic radiation for treatment of prostate, rectal or endometrial cancer subsequently developed haemorrhagic radiation proctitis.
  • Two patients subsequently presented with anorectal cancer.
  • We report the first cases of anorectal cancer which developed subsequent to formalin application.

  • Genetic Alliance. consumer health - Proctitis.
  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Radiation Therapy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17298629.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hemostatics; 1HG84L3525 / Formaldehyde
  •  go-up   go-down


10. Petrie N, Branagan G, McGuiness C, McGee S, Fuller C, Chave H: Reconstruction of the perineum following anorectal cancer excision. Int J Colorectal Dis; 2009 Jan;24(1):97-104
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reconstruction of the perineum following anorectal cancer excision.
  • PURPOSE: Most patients with anal cancer receive chemoradiotherapy as first-line treatment.
  • This study investigates a series of 18 patients who underwent APR for anorectal cancer with flap reconstruction of their perineum.
  • MATERIALS AND METHODS: A retrospective analysis of all anorectal cancers requiring an APR and flap reconstruction was performed.
  • RESULTS: Between November 2000 and October 2007, 18 cases were performed (M/F = 7:11), six for anal cancer and 12 for low rectal tumours.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18688618.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


11. Sato M, Ogawa H, Shibata C, Miura K, Ando T, Saijo F, Haneda S, Kakyo M, Kinouchi M, Fukushima K, Funayama Y, Takahashi K, Sasaki I: [A case of anal cancer with rapidly rising CEA in longstanding perianal Crohn disease after infliximab administration]. Nihon Shokakibyo Gakkai Zasshi; 2010 Jun;107(6):885-92
Hazardous Substances Data Bank. Infliximab .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of anal cancer with rapidly rising CEA in longstanding perianal Crohn disease after infliximab administration].
  • However, there is clinical concern about a possible correlation between an increased risk of anorectal cancer and infliximab treatment.
  • We report a case of anorectal cancer in long-standing perianal Crohn disease.
  • We suspected anorectal cancer, so abdominoperineal resection was performed.
  • Monitoring of patients with long-standing perianal Crohn disease is considered essential for early diagnosis of anal cancer after obtaining biopsy samples from perianal lesions.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Antibodies, Monoclonal / therapeutic use. Anus Neoplasms / diagnosis. Carcinoembryonic Antigen / blood. Crohn Disease / drug therapy. Gastrointestinal Agents / therapeutic use

  • Genetic Alliance. consumer health - Crohn Disease.
  • Genetic Alliance. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Crohn's Disease.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20530924.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Carcinoembryonic Antigen; 0 / Gastrointestinal Agents; B72HH48FLU / Infliximab
  •  go-up   go-down


12. Meyer JJ, Willett CG, Czito BG: Emerging role of intensity-modulated radiation therapy in anorectal cancer. Expert Rev Anticancer Ther; 2008 Apr;8(4):585-93
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Emerging role of intensity-modulated radiation therapy in anorectal cancer.
  • This article reviews the rationale for its use in treating anorectal tumors and discusses early clinical data supporting its continued investigation.
  • [MeSH-minor] Bone Marrow / radiation effects. Dose-Response Relationship, Radiation. Femur / radiation effects. Humans. Intestine, Small / radiation effects. Radiotherapy Dosage. Radiotherapy Planning, Computer-Assisted / methods. Radiotherapy, Intensity-Modulated / adverse effects. Radiotherapy, Intensity-Modulated / methods. Skin / radiation effects. Urinary Bladder / radiation effects

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18402525.001).
  • [ISSN] 1744-8328
  • [Journal-full-title] Expert review of anticancer therapy
  • [ISO-abbreviation] Expert Rev Anticancer Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 58
  •  go-up   go-down


13. Lacy BE, Weiser K: Common anorectal disorders: diagnosis and treatment. Curr Gastroenterol Rep; 2009 Oct;11(5):413-9
MedlinePlus Health Information. consumer health - Anal Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Common anorectal disorders: diagnosis and treatment.
  • Anorectal disorders affect men and women of all ages.
  • Rather, a spectrum of anorectal disorders ranges from benign and irritating (pruritus ani) to potentially life-threatening (anorectal cancer).
  • Some of the most common anorectal disorders include fecal incontinence, pelvic floor dyssynergia, anal fissures, pruritus ani, proctalgia fugax, and solitary rectal ulcer syndrome.
  • This article provides an update on the evaluation and treatment of common anorectal disorders.
  • [MeSH-major] Anus Diseases / diagnosis. Anus Diseases / therapy
  • [MeSH-minor] Anus Neoplasms / diagnosis. Anus Neoplasms / therapy. Diagnosis, Differential. Fecal Incontinence / diagnosis. Fecal Incontinence / therapy. Female. Fissure in Ano / diagnosis. Fissure in Ano / therapy. Hemorrhoids / diagnosis. Hemorrhoids / therapy. Humans. Male. Meta-Analysis as Topic. Prolapse. Pruritus Ani / diagnosis. Pruritus Ani / therapy. Randomized Controlled Trials as Topic. Rectal Diseases / diagnosis. Rectal Diseases / therapy. Rectal Neoplasms / diagnosis. Rectal Neoplasms / therapy. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19765370.001).
  • [ISSN] 1534-312X
  • [Journal-full-title] Current gastroenterology reports
  • [ISO-abbreviation] Curr Gastroenterol Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


14. Wanebo HJ, Begossi G, Belliveau J, Gustafson E: Isolated chemotherapeutic perfusion as neoadjuvant therapy for advanced/unresectable pelvic malignancy. J Clin Oncol; 2009 May 20;27(15_suppl):2555

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: 42 patients had advanced (irradiated) rectal cancer, 8 pts had advanced anorectal cancer, 5 patients had sarcoma.
  • Other cancers included melanoma (M 4pts), endometrial cancer (EC) 2, ovarian cancer (OC) 2, and bladder cancer (BC) 1.
  • Chemotherapy agents included 5FU, (1,500-2,000mg/M<sup>2</sup>), cisplatinum (100mg/M<sup>2</sup>), Oxaliplatin and mitomycin (10-20mg/M<sup>2</sup>) for epithelial cancer and selected agents (Adriamycin, Ifosamide, DTIC, Phenyl Alanine Mustard (PAM) for the remaining tumors: 6 pts received high dose PAM (110/M<sup>2</sup>), Paclitaxel 60mg/m<sup>2</sup> and Cisplatin 150mg/m<sup>2</sup>, 3 required stem cell support (advanced M (1 pt), SCC (1 pt), Endometrial ca (1pt).
  • RESULTS: Palliative IPP for advanced rectal cancer pts provided significant pain control (1-4 months) in 11 of 14 pts with narcotic resistant pain and induced tumor regression in 6 pts.
  • Preoperative perfusion in 26 advanced rectal cancer pts induced a complete path response (in pelvis) in 2 pts and significant regression in 11 pts rendering them resectable.
  • It was 30 months in 8 pts with advanced anorectal squamous cancer (1pt survived >90 mos), 20 months in 4 patients with endometrial/ovarian recurrence, (1 died NED >48 mos), 13 mos in 4 melanoma pts and only 5 months in 5 pts pelvic sarcoma (4-34 mos-NED).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27961873.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. Chessin DB, Hartley J, Cohen AM, Mazumdar M, Cordeiro P, Disa J, Mehrara B, Minsky BD, Paty P, Weiser M, Wong WD, Guillem JG: Rectus flap reconstruction decreases perineal wound complications after pelvic chemoradiation and surgery: a cohort study. Ann Surg Oncol; 2005 Feb;12(2):104-10
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The study group consisted of 19 patients with anorectal cancer treated with external beam pelvic radiation followed by APR and RAM flap reconstruction of the perineum.
  • A prospectively collected database was queried to identify a control group (n = 59) with anorectal cancer treated with similar radiation doses that subsequently underwent an APR without a RAM flap during the same time period.
  • CONCLUSIONS: Perineal closure with a RAM flap significantly decreases the incidence of perineal wound complications in patients undergoing external beam pelvic radiation and APR for anorectal neoplasia.


16. Lad SV, Haider MA, Brown CJ, Mcleod RS: MRI appearance of perianal carcinoma in Crohn's disease. J Magn Reson Imaging; 2007 Dec;26(6):1659-62
Hazardous Substances Data Bank. GADOPENTETATE DIMEGLUMINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The purpose of this study was to describe the MRI appearance of anorectal cancer in patients with perianal Crohn's disease.
  • A total of six patients with anorectal carcinoma (four mucinous adenocarcinoma, two squamous) in Crohn's disease were retrospectively reviewed.
  • The combined features of an irregular internal wall and delayed enhancing tissue were seen exclusively in cancer patients.
  • The pattern of contrast enhancement is valuable in the MRI diagnosis of carcinoma in perianal Crohn's disease.

  • Genetic Alliance. consumer health - Crohn Disease.
  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Crohn's Disease.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17968942.001).
  • [ISSN] 1053-1807
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 84F6U3J2R6 / gadodiamide; K2I13DR72L / Gadolinium DTPA
  •  go-up   go-down


17. Boccola MA, Rozen WM, Ek EW, Teh BM, Croxford M, Grinsell D: Inferior gluteal artery myocutaneous island transposition flap reconstruction of irradiated perineal defects. J Plast Reconstr Aesthet Surg; 2010 Jul;63(7):1169-75
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: With the progressive use of more radical surgical resections and pre-operative chemo-radiotherapy for locally advanced anorectal cancers, there has become an increasing need for reconstructive options that import well-vascularised tissue of sufficient bulk to the perineum.
  • We present our technique of inferior gluteal artery myocutaneous (IGAM) transposition flaps for reconstruction after extended abdomino-perineal excision (APE) for anorectal cancer.
  • CONCLUSION: The IGAM island transposition flap provides excellent tissue bulk, a large reliable skin paddle and a long pedicle that permits flexible positioning with tension free closure.

  • MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 19574116.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


18. Huynh D, Vincan E, Mantamadiotis T, Purcell D, Chan CK, Ramsay R: Oncogenic properties of HIV-Tat in colorectal cancer cells. Curr HIV Res; 2007 Jul;5(4):403-9
HIV InSite. treatment guidelines - Human Herpesvirus-8 .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oncogenic properties of HIV-Tat in colorectal cancer cells.
  • With the advent of Highly-Active-Anti-Retroviral-Therapy (HAART), HIV patients can expect to live beyond 10-15 years following diagnosis.
  • An unexpected result of increased survival is the emergence of opportunistic, oncogenic virus-associated cancers such as Burkitt's lymphoma (Epstein-Barr Virus), cervical cancer (Human Papilloma Virus) and Kaposi's sarcoma (Kaposi's sarcoma-associated herpesvirus) in this immuno-compromised population.
  • Compared to the general, non-immuno-compromised population, long-term AIDS patients have 4 and 3.3-fold increased risk of developing colorectal and anorectal cancer respectively.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • Genetic Alliance. consumer health - HIV.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - HIV/AIDS.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17627503.001).
  • [ISSN] 1873-4251
  • [Journal-full-title] Current HIV research
  • [ISO-abbreviation] Curr. HIV Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Gene Products, tat; 0 / tat Gene Products, Human Immunodeficiency Virus
  •  go-up   go-down


19. Masterson TA, Wedmid A, Sandhu JS, Eastham JA: Outcomes after radical prostatectomy in men receiving previous pelvic radiation for non-prostate malignancies. BJU Int; 2009 Aug;104(4):482-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS AND METHODS: From 1993 to 2007, nine patients had RP after external beam RT for testicular seminoma (six), anorectal cancer (two) and colon cancer (one).
  • Clinical information was obtained from a prospective prostate cancer database.

  • MedlinePlus Health Information. consumer health - Erectile Dysfunction.
  • MedlinePlus Health Information. consumer health - Prostate Cancer.
  • MedlinePlus Health Information. consumer health - Urinary Incontinence.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Urol. 1994 Nov;152(5 Pt 2):1850-7 [7523733.001]
  • [Cites] Urology. 1992 Sep;40(3):197-200 [1523739.001]
  • [Cites] J Urol. 1995 Sep;154(3):1103-9 [7543608.001]
  • [Cites] J Urol. 1996 Nov;156(5):1707-13 [8863576.001]
  • [Cites] J Urol. 1997 May;157(5):1760-7 [9112522.001]
  • [Cites] J Urol. 2004 Dec;172(6 Pt 1):2239-43 [15538239.001]
  • [Cites] J Urol. 2005 Apr;173(4):1156-60 [15758726.001]
  • [Cites] Dis Colon Rectum. 2005 Mar;48(3):438-43 [15719190.001]
  • [Cites] Urology. 2005 Sep;66(3):623-6 [16140090.001]
  • [Cites] Urology. 2005 Nov;66(5 Suppl):83-94 [16194712.001]
  • [Cites] Urol Clin North Am. 2001 Aug;28(3):555-65 [11590814.001]
  • [Cites] J Urol. 2002 Feb;167(2 Pt 1):528-34 [11792912.001]
  • [Cites] J Urol. 2003 Feb;169(2):517-23 [12544300.001]
  • [Cites] Lancet Oncol. 2003 Sep;4(9):529-36 [12965273.001]
  • [Cites] Cancer. 1988 Apr 1;61(7):1464-6 [3345498.001]
  • [Cites] J Urol. 1989 Mar;141(3):564-6 [2918593.001]
  • [Cites] Cancer. 1991 Sep 15;68(6):1265-71 [1873780.001]
  • [Cites] J Urol. 1992 Mar;147(3 Pt 2):894-9 [1538491.001]
  • [Cites] J Urol. 1995 Jan;153(1):104-10 [7526002.001]
  • (PMID = 19239447.001).
  • [ISSN] 1464-410X
  • [Journal-full-title] BJU international
  • [ISO-abbreviation] BJU Int.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P50 CA092629; United States / NCI NIH HHS / CA / P50 CA092629-09
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS192129; NLM/ PMC2865893
  •  go-up   go-down


20. Nisar PJ, Scott HJ: Myocutaneous flap reconstruction of the pelvis after abdominoperineal excision. Colorectal Dis; 2009 Oct;11(8):806-16
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Perineal wound complications after abdominoperineal excision (APE) for anorectal cancer represent a considerable source of morbidity for patients.
  • The implications of an expanding role for radiotherapy in the treatment of low rectal cancer and radical dissection to achieve negative circumferential margins, necessitate close co-operation between colorectal and reconstructive surgeons to achieve APE with reduced wound morbidity.

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19055518.001).
  • [ISSN] 1463-1318
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 51
  •  go-up   go-down


21. Boland E, Hsu A, Brand MI, Saclarides TJ: Hartmann's colostomy reversal: outcome of patients undergoing surgery with the intention of eliminating fecal diversion. Am Surg; 2007 Jul;73(7):664-7; discussion 668
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Twenty-one (60%) patients had their Hartmann's for diverticular disease, 7 (20%) for anorectal cancer, 4 (11%) for volvulus, and 3 for miscellaneous reasons.

  • MedlinePlus Health Information. consumer health - After Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17674937.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


22. Butler CE, Gündeslioglu AO, Rodriguez-Bigas MA: Outcomes of immediate vertical rectus abdominis myocutaneous flap reconstruction for irradiated abdominoperineal resection defects. J Am Coll Surg; 2008 Apr;206(4):694-703
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Perineal wound complications after chemoradiotherapy and abdominoperineal resection (APR) for anorectal cancer occur in up to 60% of patients, including perineal abscess and wound dehiscence.
  • STUDY DESIGN: All patients who underwent chemoradiotherapy and APR during a 12-year period at the University of Texas MD Anderson Cancer Center were retrospectively reviewed.

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18387476.001).
  • [ISSN] 1879-1190
  • [Journal-full-title] Journal of the American College of Surgeons
  • [ISO-abbreviation] J. Am. Coll. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  •  go-up   go-down


23. Ding WX, Yang P, Deng JZ, Cheng LQ, Liao S: [Comparative study of colostomy in the laparoscopic-assisted abdominoperineal resection]. Zhonghua Wei Chang Wai Ke Za Zhi; 2007 Jul;10(4):326-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Sixty- three cases with anorectal cancer undergone LAPR from June 2001 to December 2005 were registered and followed up.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Anal Canal / surgery. Female. Humans. Laparoscopy. Male. Middle Aged. Neoplasm Staging

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17659454.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


24. Eltinay OF, Guraya SY: Colorectal carcinoma: clinico-pathological pattern and outcome of surgical management. Saudi J Gastroenterol; 2006 Apr-Jun;12(2):83-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The case reports of all patients diagnosed to have colorectal cancer were retrospectively examined for: age, sex, symptoms and clinical findings, site of primary tumour and extent of metastases, operative management, histopathology results and the outcome of surgical therapy.
  • Right side tumour was encountered in twenty-one (48.8%) cases, left side tumour in twelve (27.9%) and anorectal cancer in ten (23.2%).For these lesions, thirty (69.7%) curative and thirteen (30.3%) palliative procedures were undertaken.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19858591.001).
  • [ISSN] 1998-4049
  • [Journal-full-title] Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
  • [ISO-abbreviation] Saudi J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  •  go-up   go-down


25. Prete F, Prete FP, Nitti P, De Luca R, Vincenti L: [Evolution of surgery for cancer of the anorectal junction]. Chir Ital; 2007 Nov-Dec;59(6):763-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Evolution of surgery for cancer of the anorectal junction].
  • Certain aspects of the epidemiology, classification and therapy of adenocarcinoma of the anorectal junction (< 5 cm from the anal verge) are not well standardised to date.
  • From 1989 to 2005 we treated 183 adenocarcinomas of the anorectal junction with a curative intent by 106 total proctetomies (84 of which by intersphinteric resection), 54 abdominoperineal resections, 22 transanal local excision and 1 Hartmann procedure.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Colostomy. Female. Follow-Up Studies. Humans. Ileostomy. Laparoscopy. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Postoperative Care. Preoperative Care. Proctoscopy. Radiotherapy, Adjuvant. Rectum / pathology. Time Factors. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18360980.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] ita
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


26. Row D, Weiser MR: Anorectal melanoma. Clin Colon Rectal Surg; 2009 May;22(2):120-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal melanoma.
  • The authors review the epidemiologic, clinicopathologic, and molecular features of anorectal melanoma, and discuss the differences between this uncommon and lethal disease and the more common and curable cutaneous form.
  • The recent discovery that the KIT oncogene may be aberrantly activated in a subset of patients with anorectal melanoma creates a realm of possibility for the development of targeted molecular therapy.
  • Melanoma of the anorectum is an extremely rare tumor that is often difficult to diagnose.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer. 1999 Apr 15;85(8):1686-93 [10223561.001]
  • [Cites] Br J Surg. 1986 Jan;73(1):68-9 [3947881.001]
  • [Cites] J Clin Oncol. 1999 Sep;17(9):2745-51 [10561349.001]
  • [Cites] J Clin Oncol. 2002 Dec 1;20(23):4555-8 [12454112.001]
  • [Cites] J Am Coll Surg. 2003 Feb;196(2):206-11 [12595048.001]
  • [Cites] Cancer. 2005 Mar 1;103(5):1000-7 [15651058.001]
  • [Cites] Lancet Oncol. 2005 Jun;6(6):438-9 [15925823.001]
  • [Cites] Ann Surg. 2006 Dec;244(6):1012-7 [17122627.001]
  • [Cites] Int J Cancer. 2007 Jul 15;121(2):257-64 [17372901.001]
  • [Cites] Radiother Oncol. 1989 Nov;16(3):169-82 [2587808.001]
  • [Cites] Acta Radiol Oncol. 1986 Jan-Feb;25(1):1-10 [3010642.001]
  • [Cites] Dis Colon Rectum. 1997 Jun;40(6):661-8 [9194459.001]
  • [Cites] Cancer. 1981 Apr 1;47(7):1891-900 [6164474.001]
  • [Cites] Dis Colon Rectum. 1995 Feb;38(2):146-51 [7851168.001]
  • [Cites] Cancer. 1998 Oct 15;83(8):1664-78 [9781962.001]
  • [Cites] Dis Colon Rectum. 1999 Sep;42(9):1203-8 [10496563.001]
  • (PMID = 20436837.001).
  • [ISSN] 1530-9681
  • [Journal-full-title] Clinics in colon and rectal surgery
  • [ISO-abbreviation] Clin Colon Rectal Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2780244
  • [Keywords] NOTNLM ; Melanoma / adjuvant treatment / anorectal disease / molecular therapy
  •  go-up   go-down


27. Balicevic D, Tomic K, Bekavac-Beslin M, Kovacevic I, Mijic A, Belicza M, Kruslin B: Synchronous anorectal melanoma. World J Gastroenterol; 2006 Jun 7;12(21):3453-5
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous anorectal melanoma.
  • Anorectal melanoma is a very rare tumor with poor prognosis.
  • We report a case of a 75-years-old male patient who presented with a history of recurrent rectal bleeding, and whose histopathological diagnosis was melanoma.
  • Macroscopically, we found two distinct tumors in anorectal region, 0.5 cm and 1.5 cm from dentate line.
  • Microscopic examination and immunohistochemical analysis of both tumors confirmed the diagnosis of melanoma.
  • This case represents multiple synchronous primary melanoma of the anorectal region, with a possibility that one of the lesions is primary melanoma and the second one is a satellite lesion.
  • [MeSH-major] Anus Neoplasms / diagnosis. Melanoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Rectal Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Eur J Surg. 2000 Jul;166(7):583-4 [10965842.001]
  • [Cites] Cancer Control. 2002 Jan-Feb;9(1):9-15 [11907461.001]
  • [Cites] Dis Colon Rectum. 1982 Oct;25(7):693-703 [7128372.001]
  • [Cites] Surgery. 1990 Jan;107(1):1-9 [2296748.001]
  • [Cites] Dis Colon Rectum. 1990 Oct;33(10):874-7 [1698595.001]
  • [Cites] Gastroenterology. 1993 Jan;104(1):174-8 [8419240.001]
  • [Cites] Dis Colon Rectum. 1995 Feb;38(2):146-51 [7851168.001]
  • [Cites] Cancer. 1997 Jan 1;79(1):18-25 [8988722.001]
  • [Cites] Dis Colon Rectum. 1997 Jun;40(6):661-8 [9194459.001]
  • [Cites] World J Gastroenterol. 2005 Apr 14;11(14):2197-9 [15810093.001]
  • (PMID = 16733870.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4087884
  •  go-up   go-down


28. Sarli L, Cinieri FG, Pavlidis C, Regina G, Sansebastiano G, Veronesi L, Ferro M, Violi V, Roncoroni L: Anorectal function problems after left hemicolectomy. J Laparoendosc Adv Surg Tech A; 2006 Dec;16(6):565-71
MedlinePlus Health Information. consumer health - Rectal Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal function problems after left hemicolectomy.
  • BACKGROUND: The aim of this study was to evaluate the subjective anorectal function in patients with left hemicolectomy and to clarify the clinical factors influencing postoperative anorectal function problems.
  • MATERIALS AND METHODS: One hundred and twenty one patients who underwent left hemicolectomy from April 2002 to December 2003 were enrolled in this study and sent questionnaires concerning anorectal function.
  • Left hemicolectomy in patients with cancer was performed by high ligation of the inferior mesenteric artery; in patients with diverticulitis or polyposis, the inferior mesenteric artery was cut just below the branch of the left colonic artery.
  • RESULTS: Anorectal function problems was present in 33% of patients: female gender (P = 0.02), laparoscopic surgery (P = 0.04), and postoperative diarrhea (P = 0.04) had significant independent effects on anorectal function problems.
  • CONCLUSION: In our study the following two issues were clarified: anorectal function problems are frequent after left hemicolectomy, and the laparoscopic technique is linked to poor postoperative anorectal function.

  • MedlinePlus Health Information. consumer health - Colonic Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17243871.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


29. Abbasakoor F, Vaizey CJ, Boulos PB: Improving the morbidity of anorectal injury from pelvic radiotherapy. Colorectal Dis; 2006 Jan;8(1):2-10
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Improving the morbidity of anorectal injury from pelvic radiotherapy.
  • OBJECTIVE: Radiation anorectal injury due to pelvic radiotherapy for non intestinal cancer is a significant cause of morbidity which may limit the treatment dose required.
  • This review addresses radioprotection of the anorectum and aims to increase awareness amongst surgeons of the strategies that have been in practice in order to minimize the side-effects of radiotherapy while preserving its therapeutic efficacy.
  • METHODS: This review is based on a literature search (Medline and NLM PubMed) with manual cross-referencing of all articles related to anorectal radiation injury.
  • There are few data on the potential of altered fractionation schedules in reducing anorectal injury.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16519631.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiation-Protective Agents
  • [Number-of-references] 78
  •  go-up   go-down


30. Lupattelli M, Mascioni F, Bellavita R, Draghini L, Tarducci R, Castagnoli P, Russo G, Aristei C: Long-term anorectal function after postoperative chemoradiotherapy in high-risk rectal cancer patients. Tumori; 2010 Jan-Feb;96(1):34-41
Genetic Alliance. consumer health - Rectal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term anorectal function after postoperative chemoradiotherapy in high-risk rectal cancer patients.
  • AIMS AND BACKGROUND: After sphincter-preserving surgery for rectal cancer and postoperative radiochemotherapy, many patients have unsatisfactory anorectal functional results which are not considered by the most common toxicity scales.
  • The aim of the present study was to retrospectively assess the long-term incidence of impaired anorectal function in rectal cancer patients who underwent anterior resection and postoperative radiochemotherapy.
  • METHODS: Ninety-nine patients who underwent sphincter-saving surgery and postoperative radiochemotherapy for stage II-III rectal cancer from July 1991 to January 2002 were given a questionnaire on anorectal function.
  • Factors influencing anorectal function were examined.
  • CONCLUSIONS: Although retrospective, the present study included a large selected series that had undergone uniform adjuvant treatment and was followed for a median of 10 years.
  • Anorectal function assessment should enter routinely in clinical practice and should have importance in the therapeutic decisions.
  • [MeSH-minor] Activities of Daily Living. Adult. Aged. Anastomosis, Surgical. Chemotherapy, Adjuvant. Constriction, Pathologic. Defecation. Female. Flatulence. Humans. Male. Middle Aged. Neoadjuvant Therapy / methods. Neoplasm Staging. Quality of Life. Radiotherapy, Adjuvant. Retrospective Studies. Surveys and Questionnaires. Time Factors

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20437855.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


31. Schubert MC, Sridhar S, Schade RR, Wexner SD: What every gastroenterologist needs to know about common anorectal disorders. World J Gastroenterol; 2009 Jul 14;15(26):3201-9
MedlinePlus Health Information. consumer health - Rectal Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] What every gastroenterologist needs to know about common anorectal disorders.
  • Anorectal complaints are very common and are caused by a variety of mostly benign anorectal disorders.
  • Many anorectal conditions may be successfully treated by primary care physicians in the outpatient setting, but patients tend not to seek medical attention due to embarrassment or fear of cancer.
  • A number of patients with anorectal complaints are referred to gastroenterologists.
  • This article can serve as a guide to gastroenterologists to recognize, evaluate, and manage medically or non-surgically common benign anorectal disorders, and to identify when surgical referrals are most prudent.
  • Topics reviewed include hemorrhoids, anal fissures, anorectal fistulas and abscesses, and pruritus ani.
  • [MeSH-minor] Abscess / diagnosis. Abscess / physiopathology. Abscess / therapy. Fissure in Ano / diagnosis. Fissure in Ano / physiopathology. Fissure in Ano / therapy. Hemorrhoids / diagnosis. Hemorrhoids / physiopathology. Hemorrhoids / therapy. Humans. Pruritus Ani / diagnosis. Pruritus Ani / physiopathology. Pruritus Ani / therapy. Rectal Fistula / diagnosis. Rectal Fistula / physiopathology. Rectal Fistula / therapy

  • MedlinePlus Health Information. consumer health - Anal Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Gut. 1999 May;44(5):727-30 [10205213.001]
  • [Cites] Br J Surg. 1999 Oct;86(10):1337-40 [10540145.001]
  • [Cites] Dis Colon Rectum. 2000 Feb;43(2):174-9; discussion 179-81 [10696890.001]
  • [Cites] Lancet. 2000 Mar 4;355(9206):779-81 [10711924.001]
  • [Cites] Am J Surg. 2000 Jan;179(1):46-50 [10737578.001]
  • [Cites] Dis Colon Rectum. 2000 Aug;43(8):1048-57; discussion 1057-8 [10950002.001]
  • [Cites] Lancet. 2000 Aug 26;356(9231):730-3 [11085693.001]
  • [Cites] Dis Colon Rectum. 2000 Dec;43(12):1666-75 [11156449.001]
  • [Cites] Radiology. 2001 Jan;218(1):75-84 [11152782.001]
  • [Cites] Br J Surg. 2001 Apr;88(4):553-6 [11298624.001]
  • [Cites] Dis Colon Rectum. 2001 Apr;44(4):558-64 [11330583.001]
  • [Cites] Dis Colon Rectum. 2001 May;44(5):722-7 [11357036.001]
  • [Cites] Dis Colon Rectum. 2001 Jun;44(6):845-9 [11391146.001]
  • [Cites] Br J Surg. 2002 Apr;89(4):413-7 [11952579.001]
  • [Cites] Dis Colon Rectum. 2002 Jun;45(6):789-94 [12072632.001]
  • [Cites] Surg Clin North Am. 2002 Dec;82(6):1153-67, vi [12516845.001]
  • [Cites] Dis Colon Rectum. 2003 Mar;46(3):361-6 [12626912.001]
  • [Cites] Dis Colon Rectum. 2003 May;46(5):584-9 [12792432.001]
  • [Cites] Dis Colon Rectum. 2004 Apr;47(4):432-6 [14978618.001]
  • [Cites] Dis Colon Rectum. 2004 Apr;47(4):422-31 [14994109.001]
  • [Cites] Tech Coloproctol. 2004 Mar;8(1):11-4 [15057582.001]
  • [Cites] Postgrad Med J. 2004 May;80(943):295-7 [15138322.001]
  • [Cites] South Med J. 2004 Jul;97(7):710 [15301134.001]
  • [Cites] Proc R Soc Med. 1970;63 Suppl:96-8 [5525836.001]
  • [Cites] Br J Surg. 1975 Jul;62(7):542-52 [1174785.001]
  • [Cites] Br J Surg. 1976 Jan;63(1):1-12 [1267867.001]
  • [Cites] Gut. 1977 Aug;18(8):651-5 [892612.001]
  • [Cites] Surg Clin North Am. 1978 Jun;58(3):505-12 [675463.001]
  • [Cites] Dis Colon Rectum. 1980 Nov-Dec;23(8):570-1 [7460695.001]
  • [Cites] Dis Colon Rectum. 1982 May-Jun;25(4):336-9 [6979470.001]
  • [Cites] Dis Colon Rectum. 1982 Jul-Aug;25(5):454-6 [6284457.001]
  • [Cites] Dis Colon Rectum. 1983 Feb;26(2):134-8 [6337034.001]
  • [Cites] Br Med J (Clin Res Ed). 1983 Apr 30;286(6375):1387-9 [6404471.001]
  • [Cites] J Dermatol Surg Oncol. 1984 Jun;10(6):483-4 [6725744.001]
  • [Cites] Dis Colon Rectum. 1984 Jul;27(7):442-50 [6745015.001]
  • [Cites] Dis Colon Rectum. 1985 May;28(5):291-3 [3888558.001]
  • [Cites] Dis Colon Rectum. 1985 Nov;28(11):832-5 [4053894.001]
  • [Cites] Dis Colon Rectum. 1986 Apr;29(4):248-51 [3948615.001]
  • [Cites] Br Med J (Clin Res Ed). 1986 May 3;292(6529):1167-9 [3011180.001]
  • [Cites] Br J Surg. 1986 Jun;73(6):443-5 [3719268.001]
  • [Cites] Gastroenterol Clin North Am. 1987 Mar;16(1):93-114 [3298058.001]
  • [Cites] Br J Surg. 1987 Jul;74(7):576-9 [3620861.001]
  • [Cites] Dermatol Clin. 1987 Oct;5(4):811-6 [3315360.001]
  • [Cites] Br J Surg. 1989 May;76(5):431-4 [2736353.001]
  • [Cites] Dis Colon Rectum. 1989 Oct;32(10):839-42 [2791768.001]
  • [Cites] Gastroenterology. 1990 Feb;98(2):380-6 [2295392.001]
  • [Cites] Int J Colorectal Dis. 1990 May;5(2):113-6 [2358736.001]
  • [Cites] Dis Colon Rectum. 1990 Jul;33(7):587-9 [1694476.001]
  • [Cites] Neth J Med. 1990 Aug;37 Suppl 1:S33-6 [2172846.001]
  • [Cites] Br J Surg. 1991 Oct;78(10):1159-61 [1958973.001]
  • [Cites] Dis Colon Rectum. 1992 May;35(5):477-81 [1568400.001]
  • [Cites] Am J Gastroenterol. 1992 Nov;87(11):1600-6 [1442682.001]
  • [Cites] J Am Coll Surg. 1994 Jun;178(6):600-4 [8193753.001]
  • [Cites] Br J Surg. 1994 Apr;81(4):603-6 [8205448.001]
  • [Cites] Dis Colon Rectum. 1994 Jul;37(7):670-4 [8026233.001]
  • [Cites] Lancet. 1994 Oct 22;344(8930):1127-8 [7934496.001]
  • [Cites] Br J Surg. 1994 Sep;81(9):1386-9 [7953427.001]
  • [Cites] Lancet. 1995 Jan 21;345(8943):188-9 [7823680.001]
  • [Cites] Dis Colon Rectum. 1995 Jul;38(7):687-94 [7607026.001]
  • [Cites] Br J Surg. 1995 Apr;82(4):448-52 [7613885.001]
  • [Cites] N Engl J Med. 1995 Oct 26;333(17):1156-7 [7565967.001]
  • [Cites] Br J Surg. 1996 Jan;83(1):112 [8653331.001]
  • [Cites] Gastrointest Endosc. 1996 Dec;44(6):731-3 [8979068.001]
  • [Cites] N Engl J Med. 1999 May 6;340(18):1398-405 [10228190.001]
  • [Cites] Dis Colon Rectum. 1999 Aug;42(8):1007-10 [10458122.001]
  • [Cites] Dis Colon Rectum. 1999 Sep;42(9):1152-9 [10496555.001]
  • [Cites] Dis Colon Rectum. 1999 Oct;42(10):1306-10 [10528769.001]
  • [Cites] Radiology. 2004 Dec;233(3):674-81 [15498901.001]
  • [Cites] Dis Colon Rectum. 2005 Feb;48(2):344-8 [15616753.001]
  • [Cites] Dermatol Ther. 2005 Jul-Aug;18(4):355-62 [16297009.001]
  • [Cites] Dis Colon Rectum. 2005 Dec;48(12):2336-40 [15981059.001]
  • [Cites] Radiology. 2006 Apr;239(1):18-33 [16567481.001]
  • [Cites] Int J Colorectal Dis. 2006 Dec;21(8):791-4 [16625375.001]
  • [Cites] Dis Colon Rectum. 2006 Dec;49(12):1817-21 [17082891.001]
  • [Cites] Br J Surg. 2007 Feb;94(2):162-7 [17256809.001]
  • [Cites] Dis Colon Rectum. 2007 Apr;50(4):442-8 [17297553.001]
  • [Cites] Surg Today. 2007;37(6):482-5 [17522765.001]
  • [Cites] World J Gastroenterol. 2007 Jun 21;13(23):3153-8 [17589891.001]
  • [Cites] Dig Dis Sci. 2007 Aug;52(8):1920-3 [17393322.001]
  • [Cites] Hepatogastroenterology. 2007 Jun;54(76):1071-3 [17629041.001]
  • [Cites] Ann R Coll Surg Engl. 2007 Jul;89(5):472-8 [17688717.001]
  • [Cites] Dis Colon Rectum. 2007 Dec;50(12):2168-72 [17701369.001]
  • [Cites] Lancet. 1997 Jan 4;349(9044):11-4 [8988115.001]
  • [Cites] Dis Colon Rectum. 1997 Feb;40(2):229-33 [9075762.001]
  • [Cites] Dis Colon Rectum. 1997 May;40(5):597-602 [9152191.001]
  • [Cites] Br J Surg. 1997 May;84(5):670 [9171759.001]
  • [Cites] Dis Colon Rectum. 1997 Sep;40(9):1029-32 [9293930.001]
  • [Cites] N Engl J Med. 1998 Jan 22;338(4):217-20 [9435326.001]
  • [Cites] Br J Surg. 1998 Feb;85(2):243-5 [9501826.001]
  • (PMID = 19598294.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Editorial; Review
  • [Publication-country] China
  • [Number-of-references] 96
  • [Other-IDs] NLM/ PMC2710774
  •  go-up   go-down


32. Zhang S, Gao F, Wan D: Effect of misdiagnosis on the prognosis of anorectal malignant melanoma. J Cancer Res Clin Oncol; 2010 Sep;136(9):1401-5
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of misdiagnosis on the prognosis of anorectal malignant melanoma.
  • OBJECTIVE: Anorectal malignant melanoma (AMM) is frequently subjected to misdiagnosis.
  • Diseases misdiagnosed were categorized as cancer, hemorrhoids, polyps and other diseases.
  • [MeSH-major] Anus Neoplasms / diagnosis. Diagnostic Errors. Melanoma / diagnosis

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20130908.001).
  • [ISSN] 1432-1335
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


33. Belli F, Gallino GF, Lo Vullo S, Mariani L, Poiasina E, Leo E: Melanoma of the anorectal region: the experience of the National Cancer Institute of Milano. Eur J Surg Oncol; 2009 Jul;35(7):757-62
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Melanoma of the anorectal region: the experience of the National Cancer Institute of Milano.
  • AIMS: This study describes the experience of the National Cancer Institute of Milano in the treatment of anorectal melanoma over the last 32 years.

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18602790.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


34. Lundby L, Krogh K, Jensen VJ, Gandrup P, Qvist N, Overgaard J, Laurberg S: Long-term anorectal dysfunction after postoperative radiotherapy for rectal cancer. Dis Colon Rectum; 2005 Jul;48(7):1343-9; discussion 1349-52; author reply 1352
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term anorectal dysfunction after postoperative radiotherapy for rectal cancer.
  • PURPOSE: Adjuvant radiotherapy in the treatment of rectal cancer has been shown to increase long-term morbidity causing severe anorectal dysfunction with physiologic changes whose interaction remains poorly understood.
  • This study examines long-term anorectal morbidity from adjuvant postoperative radiotherapy.
  • The long-term effect of radiotherapy on anorectal function in a subset of surviving patients was assessed from a questionnaire on subjective symptoms and from physiology laboratory evaluation and flexible sigmoidoscopy.
  • Anorectal physiology showed a reduced rectal capacity (146 vs. 215 ml, P = 0.03) and maximum squeeze pressure (59 vs. 93 cm H2O, P = 0.003) in the radiotherapy group.
  • CONCLUSIONS: Adjuvant postoperative radiotherapy after anterior resection causes severe long-term anorectal dysfunction, which is mainly the result of a weakened, less sensitive anal sphincter and an undistensible rectum with reduced capacity.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15933797.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial
  • [Publication-country] United States
  •  go-up   go-down


35. Jang NY, Han TJ, Kang SB, Kim DW, Kim IA, Kim JS: The short-term effect of neoadjuvant chemoradiation on anorectal function in low and midrectal cancer: analysis using preoperative manometric data. Dis Colon Rectum; 2010 Apr;53(4):445-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The short-term effect of neoadjuvant chemoradiation on anorectal function in low and midrectal cancer: analysis using preoperative manometric data.
  • PURPOSE: The purpose of this study was to evaluate the short-term preoperative effects of neoadjuvant chemoradiation on anorectal function, excluding the bias of postoperative impairment.
  • METHODS: We analyzed 80 patients on whom preoperative anorectal manometry data were available for both prechemoradiation and postchemoradiation.
  • RESULTS: In patients with a lower rectal cancer, there were significant differences in the percentage asymmetry of the squeeze sphincter (27.81 +/- 6.46 vs 25.38 +/- 5.93%, P < .01), length of the high-pressure zone (2.14 +/- 0.74 vs 2.33 +/- 0.72 cm, P = .05), and rectal compliance (1.14 +/- 0.41 vs 1.02 +/- 0.40 mL/mmHg, P = .04).
  • In patients with midrectal cancer, only the mean resting pressure increased significantly (45.08 +/- 18.57 vs 52.83 +/- 17.87 mmHg, P < .01).
  • Although there was a decrease in rectal compliance, it seemed that the tumor-downsizing effect compensated the expected worsening of anorectal function in the early postchemoradiation period.
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chi-Square Distribution. Female. Humans. Male. Manometry. Middle Aged. Neoadjuvant Therapy. Neoplasm Staging. Retrospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20305445.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


36. Park JS, Kang SB, Kim DW, Kim NY, Lee KH, Kim YH: Iatrogenic colorectal perforation induced by anorectal manometry: report of two cases after restorative proctectomy for distal rectal cancer. World J Gastroenterol; 2007 Dec 7;13(45):6112-4
MedlinePlus Health Information. consumer health - Rectal Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Iatrogenic colorectal perforation induced by anorectal manometry: report of two cases after restorative proctectomy for distal rectal cancer.
  • There are no reports regarding perforation of the colorectum induced by anorectal manometry.
  • We report two cases of colorectal perforation that occurred during manometry in the patients undergoing restorative proctectomy for distal rectal cancer.
  • We hypothesize that the perforation induced by anorectal manometry may be associated with the relative weakening of the proximal bowel wall due to anastomosis, decreased compliance, and abnormal rectal sensation.
  • We suggest that measurement of the maximum tolerable volume should not be routinely performed after restorative proctectomy for distal rectal cancer.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • Genetic Alliance. consumer health - Rectal Cancer.
  • MedlinePlus Health Information. consumer health - Colonic Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18023112.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4250903
  •  go-up   go-down


37. Badgwell BD, Chang GJ, Rodriguez-Bigas MA, Smith K, Lupo PJ, Frankowski RF, Delclos G, Du XL, Cormier J: Management and outcomes of anorectal infection in the cancer patient. Ann Surg Oncol; 2009 Oct;16(10):2752-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management and outcomes of anorectal infection in the cancer patient.
  • BACKGROUND: The objective of this retrospective cohort study is to examine the presentation and outcomes for a contemporary series of cancer patients with anorectal infection.
  • METHODS: The study cohort was identified from International Classification of Disease (ICD)-9 codes for diagnosis of infection of the anal and rectal region and patients who underwent a surgical oncology consultation at The University of Texas M.D.
  • Anderson Cancer Center between 1/2000 and 12/2006.
  • RESULTS: Of the 100 patients evaluated by the surgical oncology service for anorectal infection, 42 were treated nonoperatively and 58 underwent surgical intervention.
  • Factors associated with surgical intervention based on logistic multivariable analysis included diagnosis of an abscess [odds ratio (OR) 10.5, 95% confidence interval (CI) 2.9-38.5] and documentation of erythema on physical examination (OR 3.1, 95% CI 1.1-8.4).
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Anti-Infective Agents / therapeutic use. Cohort Studies. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Survival Rate. Treatment Outcome. Young Adult

  • MedlinePlus Health Information. consumer health - Anal Disorders.
  • MedlinePlus Health Information. consumer health - Bacterial Infections.
  • MedlinePlus Health Information. consumer health - Rectal Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19649556.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Infective Agents
  •  go-up   go-down


38. Zhao DB, Wu YK, Shao YF: [Analysis of recurrence and prognosis after surgical resection for anorectal melanoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2007 Nov;10(6):540-2
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of recurrence and prognosis after surgical resection for anorectal melanoma].
  • OBJECTIVE: To investigate the clinicopathologic factors related with recurrence and prognosis after surgical resection for anorectal melanoma.
  • METHODS: The clinicopathologic factors related to recurrence and prognosis of 50 patients with anorectal melanoma after surgical resection were retrospectively analyzed using univariate and multivariate methods.
  • Multivariate analysis revealed that intramural infiltration was the most important prognostic factor for anorectal melanoma.
  • CONCLUSIONS: The prognosis of anorectal melanoma is poor.
  • Early diagnosis and treatment are important for the improving of curative effect.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Prognosis. Retrospective Studies. Survival Rate

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18000775.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


39. Radcliffe A: Can the results of anorectal (abdominoperineal) resection be improved: are circumferential resection margins too often positive? Colorectal Dis; 2006 Mar;8(3):160-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Can the results of anorectal (abdominoperineal) resection be improved: are circumferential resection margins too often positive?
  • Carefully executed surgery for rectal cancer has reduced the incidence of local recurrence after restorative resection.
  • Three recent large prospective series have confirmed the perception of a higher positive circumferential resection margin (CRM) rate after abdominoperineal resection.
  • Tumour spread is different for low tumours and the surgical technique of abdominoperineal resection, perhaps better known as anorectal excision, may vary between surgeons.
  • There is a need to redefine the place of anorectal excision and the contribution that can be made by pre-operative chemoradiation and/or extended surgery to reduce local recurrence and increase survival.
  • Unnecessary R1 or R2 resections and operative perforation can be minimized by an understanding of the surgical anatomy, the pattern of spread and difference in operative technique between anorectal excision and a low restorative operation.
  • With the adoption of even lower restorative resection (intersphincteric) there is a need to reassess the method of anorectal excision.
  • [MeSH-minor] Humans. Neoplasm Recurrence, Local / prevention & control. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16466553.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 70
  •  go-up   go-down


40. Ramakrishnan AS, Mahajan V, Kannan R: Optimizing local control in anorectal melanoma. Indian J Cancer; 2008 Jan-Mar;45(1):13-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optimizing local control in anorectal melanoma.
  • BACKGROUND: Wide local excision (WLE) of anorectal melanoma is associated with a high incidence of local recurrence.
  • AIM: To identify the optimal method of local treatment in anorectal melanoma.
  • SETTINGS AND DESIGN: Retrospective study in a tertiary cancer centre.
  • CONCLUSION: Local treatment of anorectal melanoma should be individualized.
  • WLE with adjuvant radiation seems to offer good locoregional control without reducing the survival and may be an option of treatment for patients with small, superficial anorectal melanoma.
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Digestive System Surgical Procedures. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Neoplasm Staging. Prognosis. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18453735.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  •  go-up   go-down


41. Coull DB, Lee FD, Anderson JH, McKee RF, Finlay IG, Dunlop MG: Long-term cancer risk of the anorectal cuff following restorative proctocolectomy assessed by p53 expression and cuff dysplasia. Colorectal Dis; 2007 May;9(4):321-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term cancer risk of the anorectal cuff following restorative proctocolectomy assessed by p53 expression and cuff dysplasia.
  • OBJECTIVE: Restorative proctocolectomy (RP) for ulcerative colitis (UC) retains a 'cuff' of columnar rectal epithelium that has unknown risk of malignant change.
  • Markers of malignant potential in UC include aberrant p53 expression and dysplasia.
  • We undertook a prospective study comprising serial surveillance biopsy and assessed the occurrence of aberrant p53 expression, epithelial dysplasia and carcinoma in the retained anorectal cuff following stapled RP.
  • Median follow-up was 56 months (12-145) and median time since diagnosis of UC was 8.8 years (2-32).
  • These data suggest that in patients who do not have high-grade dysplasia or colorectal cancer at the time of RP, cuff surveillance in the first decade after pouch formation is unnecessary.

  • MedlinePlus Health Information. consumer health - Ulcerative Colitis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17432983.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / MRC/ MC/ U127527198
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Protein p53
  •  go-up   go-down


42. Pollack J, Holm T, Cedermark B, Holmström B, Mellgren A: Long-term effect of preoperative radiation therapy on anorectal function. Dis Colon Rectum; 2006 Mar;49(3):345-52
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term effect of preoperative radiation therapy on anorectal function.
  • PURPOSE: Preoperative radiotherapy improves local control in rectal cancer treatment, but there are few reports on the influence of radiotherapy on anorectal function.
  • The aim of the present study was to assess late effects of short-course, high-dose radiotherapy on anorectal function after low anterior resection for rectal cancer.
  • METHODS: Sixty-four patients, randomized within the Stockholm Radiotherapy Trials and operated on with low anterior resection with or without preoperative radiotherapy (mean, 14 years), previously were followed up with quality-of-life questionnaires, clinical examination, anorectal manometry, and endoanal ultrasound.
  • RESULTS: Impaired anorectal function was common after low anterior resection for rectal cancer and the risk was increased after radiotherapy.
  • At anorectal manometry, irradiated patients had significantly lower resting (35 mmHg vs. 62 mmHg, P < 0,001) and squeeze pressures (104 mmHg vs. 143 mmHg, P = 0.05).
  • CONCLUSIONS: Short-course radiotherapy, including the anal sphincters, impairs anorectal function and increases gastrointestinal symptoms permanently when the anal sphincters are irradiated.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16532369.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


43. Khaled A, Hammami H, Fazaa B, Kourda N, Kamoun MR, Ben Jilany S, Zoghlami A: Primary amelanotic anorectal melanoma: an uncommon neoplasia with poor prognosis. Pathologica; 2009 Jun;101(3):126-9
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic anorectal melanoma: an uncommon neoplasia with poor prognosis.
  • BACKGROUND: Anorectal melanoma is a rare and aggressive mucosal cancer.
  • There is usually a delay in diagnosis because about 30% of these cancers are amelanotic and are often mistaken for benign conditions.
  • Herein, we report a case of amelanotic anorectal malignant melanoma with an unusual metastatic deposit in the vulva and also review the literature.
  • Histological examination and immunohistochemical staining of all tumours demonstrated malignant melanoma.
  • DISCUSSION: Nine cases of amelanotic malignant melanoma have been reported in the literature.
  • The age at diagnosis ranged from 45 to 77 years.
  • Anorectal melanoma is most common in the rectum, followed by the anal canal.
  • Our case is the tenth case of amelanotic anorectal melanoma and probably corresponds to multiple synchronous primary melanomas of the anorectal region and the vulva, with the possibility that one of the lesions is a primary melanoma and the others are satellite lesions.

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19886548.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


44. Berman L, Israel GM, McCarthy SM, Weinreb JC, Longo WE: Utility of magnetic resonance imaging in anorectal disease. World J Gastroenterol; 2007 Jun 21;13(23):3153-8
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Utility of magnetic resonance imaging in anorectal disease.
  • Imaging of both benign and malignant anorectal diseases has traditionally posed a challenge to clinicians, and as a result history and physical exam have been relied on heavily.
  • Anorectal disease is divided into three broad categories: cancer, fistula/abscess, and pelvic floor disorders.
  • Preoperative imaging is useful in the evaluation of all three areas of anorectal disease.
  • MRI continues to be a promising and novel approach to imaging various afflictions of the anorectum and the pelvic floor.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Rectal Fistula / diagnosis. Rectal Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17589891.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4436394
  •  go-up   go-down


45. Devesa JM, López-Hervás P, Vicente R, Rey A, Die J, Fraile A: Total anorectal reconstruction: a novel technique. Tech Coloproctol; 2005 Jul;9(2):149-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Total anorectal reconstruction: a novel technique.
  • The aim of this report is to describe a novel technical approach to total anorectal reconstruction after a Miles operation for rectal cancer.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16007357.001).
  • [ISSN] 1123-6337
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


46. Nilsson PJ, Ragnarsson-Olding BK: Importance of clear resection margins in anorectal malignant melanoma. Br J Surg; 2010 Jan;97(1):98-103
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Importance of clear resection margins in anorectal malignant melanoma.
  • BACKGROUND: Anorectal melanoma is rare and surgery is the recommended primary treatment.
  • METHODS: From the Swedish National Cancer Registry, 251 patients with anorectal melanoma were identified from 1960 to 1999.
  • CONCLUSION: Both APR and LE seem appropriate for anorectal melanoma provided clear margins can be achieved; prognosis is poor regardless of surgical approach.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Epidemiologic Methods. Humans. Middle Aged. Neoplasm Recurrence, Local / mortality

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
  • (PMID = 20013935.001).
  • [ISSN] 1365-2168
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


47. Ho KS, Seow-Choen F: Dynamic graciloplasty for total anorectal reconstruction after abdominoperineal resection for rectal tumour. Int J Colorectal Dis; 2005 Jan;20(1):38-41
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dynamic graciloplasty for total anorectal reconstruction after abdominoperineal resection for rectal tumour.
  • AIM: To review the results of dynamic graciloplasty for total anorectal reconstruction after abdominoperineal resection (APR) for rectal cancer.
  • Conversely, dynamic graciloplasty may lead to defecatory difficulties in a large number of patients.

  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15293066.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


48. Lampinen TM, Latulippe L, van Niekerk D, Schilder AJ, Miller ML, Anema A, Hogg RS: Illustrated instructions for self-collection of anorectal swab specimens and their adequacy for cytological examination. Sex Transm Dis; 2006 Jun;33(6):386-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Illustrated instructions for self-collection of anorectal swab specimens and their adequacy for cytological examination.
  • BACKGROUND: Self-collection of anorectal swab specimens would facilitate screening for anal cancer precursors and sexually transmitted rectal infections among men who have sex with men (MSM).
  • CONCLUSIONS: Provided with illustrated instructions, most MSM who are naïve to the technique can self-collect anorectal swab specimens that are suitable for screening.
  • [MeSH-major] Anal Canal / pathology. Homosexuality, Male. Self Care. Sexually Transmitted Diseases / diagnosis

  • MedlinePlus Health Information. consumer health - Sexually Transmitted Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16543863.001).
  • [ISSN] 0148-5717
  • [Journal-full-title] Sexually transmitted diseases
  • [ISO-abbreviation] Sex Transm Dis
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Reagent Kits, Diagnostic
  •  go-up   go-down


49. Anderson C, Koshy M, Staley C, Esiashvili N, Ghavidel S, Fowler Z, Fox T, Esteves F, Landry J, Godette K: PET-CT fusion in radiation management of patients with anorectal tumors. Int J Radiat Oncol Biol Phys; 2007 Sep 1;69(1):155-62
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] PET-CT fusion in radiation management of patients with anorectal tumors.
  • PURPOSE: To compare computed tomography (CT) with positron emission tomography-CT (PET-CT) scans with respect to anorectal tumor volumes, correlation in overlap, and influence on radiation treatment fields and patient care.
  • PATIENTS AND METHODS: From March to November 2003, 20 patients with rectal cancer and 3 patients with anal cancer were treated with preoperative or definitive chemoradiation, respectively.
  • For 25% of patients with rectal cancer, PET detected distant metastases and changed overall management.
  • Ten rectal cancer patients underwent surgery.
  • Positron emission tomography can change the management for anorectal tumors by early detection of metastatic disease or disease outside standard radiation fields.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Combined Modality Therapy / methods. Female. Fluorodeoxyglucose F18. Humans. Male. Middle Aged. Neoplasm Staging. Radiopharmaceuticals. Radiotherapy, Conformal / methods. Tumor Burden

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - CT Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17707268.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  •  go-up   go-down


50. Fritsch H, Zehm S, Illig R, Moser P, Aigner F: New insights into the development and differentiation of the human anorectal epithelia. Are there clinical consequences? Int J Colorectal Dis; 2010 Oct;25(10):1231-42
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] New insights into the development and differentiation of the human anorectal epithelia. Are there clinical consequences?
  • PURPOSE: The epithelial lining of the anorectum still raises discussions concerning the levels of transition between the various zones and leads to an incomplete understanding of the immmunoprofile of rectal carcinoma.
  • Since the expression of cytokeratins depends on the epithelial cell-type and the parahox-gene CDX2 is important for the development of the colorectal epithelium, we investigated different cytokeratins and CDX2 in the anorectum of human prenatal stages and in adult normal and neoplastic anorecta.
  • RESULTS: Due to the cytokeratin profile and to CDX2 expression, the different anorectal zones could already be differentiated in human prenatal life.
  • We showed that anorectal epithelial differentiation including the squamous epithelia ran in a craniocaudal direction, and that the anorectal zone was a transitional zone between rectal zone and anal transitional zone where CK 7, 18, 20 and CDX2 are simultaneously expressed.
  • CONCLUSIONS: Our results elucidate the connection between the prenatal pattern and the origin of the different types of anorectal carcinoma.

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] BJU Int. 2000 Apr;85(6):728-34 [10759675.001]
  • [Cites] Anat Rec (Hoboken). 2009 Jul;292(7):951-4 [19496155.001]
  • [Cites] Am J Surg Pathol. 2003 Mar;27(3):303-10 [12604886.001]
  • [Cites] Folia Morphol (Warsz). 2003;62(3):285-7 [14507068.001]
  • [Cites] Mod Pathol. 2004 Nov;17(11):1392-9 [15205684.001]
  • [Cites] J Pediatr Surg. 1974 Oct;9(5):755-69 [4424274.001]
  • [Cites] Cell. 1982 Sep;30(2):361-72 [6183000.001]
  • [Cites] Cell. 1982 Nov;31(1):11-24 [6186379.001]
  • [Cites] Eur J Cancer Clin Oncol. 1982 Dec;18(12):1251-7 [6187573.001]
  • [Cites] J Invest Dermatol. 1983 Jul;81(1 Suppl):109s-15s [6190956.001]
  • [Cites] Crit Rev Oncol Hematol. 1985;3(3):191-204 [2412718.001]
  • [Cites] Veroff Pathol. 1993;142:1-197 [7504860.001]
  • [Cites] Am J Pathol. 1995 Sep;147(3):586-92 [7677172.001]
  • [Cites] Arch Pathol Lab Med. 1997 Jul;121(7):719-23 [9240908.001]
  • [Cites] Adv Anat Embryol Cell Biol. 2005;177:1-131 [15615037.001]
  • [Cites] Dis Colon Rectum. 2005 Sep;48(9):1742-51 [15991058.001]
  • [Cites] Anat Rec (Hoboken). 2007 Nov;290(11):1449-58 [17853405.001]
  • [Cites] Oncogene. 2008 Jan 3;27(1):107-15 [17599044.001]
  • [Cites] Ann Anat. 2008;190(2):119-28 [18413265.001]
  • [Cites] Histol Histopathol. 2008 Sep;23(9):1043-7 [18581275.001]
  • [Cites] Appl Immunohistochem Mol Morphol. 2009 May;17(3):196-201 [19098678.001]
  • [Cites] Dev Cell. 2009 Apr;16(4):588-99 [19386267.001]
  • [Cites] Am J Surg Pathol. 2003 Feb;27(2):141-9 [12548159.001]
  • (PMID = 20563874.001).
  • [ISSN] 1432-1262
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CDX2 protein, human; 0 / Homeodomain Proteins
  • [Other-IDs] NLM/ PMC2928443
  •  go-up   go-down


51. Mandhan P, Quan QB, Beasley S, Sullivan M: Sonic hedgehog, BMP4, and Hox genes in the development of anorectal malformations in Ethylenethiourea-exposed fetal rats. J Pediatr Surg; 2006 Dec;41(12):2041-5
Hazardous Substances Data Bank. Ethylene thiourea .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sonic hedgehog, BMP4, and Hox genes in the development of anorectal malformations in Ethylenethiourea-exposed fetal rats.
  • In this study, we investigated the expression of shh and its targets, BMP4 and Hox genes, in the development of anorectal malformations in Ethylenethiourea (ETU)-exposed embryos.

  • MedlinePlus Health Information. consumer health - Rectal Disorders.
  • COS Scholar Universe. author profiles.
  • Gene Ontology. gene/protein/disease-specific - Gene Ontology annotations from this paper .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17161201.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bmp4 protein, rat; 0 / Bone Morphogenetic Protein 4; 0 / Bone Morphogenetic Proteins; 0 / Hedgehog Proteins; 24FOJ4N18S / Ethylenethiourea
  •  go-up   go-down


52. Biyikoğlu I, Oztürk ZA, Köklü S, Babali A, Akay H, Filik L, Basat O, Ozer H, Ozer E: Primary anorectal malignant melanoma: two case reports and review of the literature. Clin Colorectal Cancer; 2007 May;6(7):532-5
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary anorectal malignant melanoma: two case reports and review of the literature.
  • Anorectal melanoma is a very rare tumor with poor prognosis because of delay in diagnosis.
  • Herein, we report 2 cases of anorectal malignant melanoma and further review the diagnostic and therapeutic approaches in light of the pertinent literature.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17553203.001).
  • [ISSN] 1533-0028
  • [Journal-full-title] Clinical colorectal cancer
  • [ISO-abbreviation] Clin Colorectal Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


53. Yeh JJ, Shia J, Hwu WJ, Busam KJ, Paty PB, Guillem JG, Coit DG, Wong WD, Weiser MR: The role of abdominoperineal resection as surgical therapy for anorectal melanoma. Ann Surg; 2006 Dec;244(6):1012-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of abdominoperineal resection as surgical therapy for anorectal melanoma.
  • OBJECTIVES:. 1) Characterize changes in the surgical treatment of anorectal melanoma over time.
  • SUMMARY BACKGROUND DATA: Although early data suggested improved survival in patients undergoing abdominoperineal resection (APR) for primary anorectal melanoma, such an aggressive approach may be unwarranted as distant relapse rates are high.
  • METHODS: A retrospective review was performed of all patients with anorectal melanoma treated at our institution between 1984 and 2003.
  • CONCLUSION: The extent of surgical treatment is not associated with outcome in primary anorectal melanoma.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Retrospective Studies. Survival Rate. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Melanoma.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Surgery. 1990 Jan;107(1):1-9 [2296748.001]
  • [Cites] Br J Surg. 1986 Jan;73(1):68-9 [3947881.001]
  • [Cites] Kurume Med J. 1992;39(1):41-9 [1619888.001]
  • [Cites] Am J Surg. 1993 Feb;165(2):233-7 [8427403.001]
  • [Cites] Dis Colon Rectum. 1995 Feb;38(2):146-51 [7851168.001]
  • [Cites] Cancer. 1998 Oct 15;83(8):1664-78 [9781962.001]
  • [Cites] Cancer. 1999 Apr 15;85(8):1686-93 [10223561.001]
  • [Cites] Gastroenterology. 2004 Dec;127(6):1815-20 [15578519.001]
  • [Cites] Lancet Oncol. 2005 Jun;6(6):438-9 [15925823.001]
  • [Cites] Dis Colon Rectum. 1997 Jun;40(6):661-8 [9194459.001]
  • [Cites] Br J Surg. 2001 Jul;88(7):994-1000 [11442534.001]
  • [Cites] J Clin Oncol. 2001 Aug 15;19(16):3622-34 [11504744.001]
  • [Cites] J Am Coll Surg. 2003 Feb;196(2):206-11 [12595048.001]
  • [Cites] Br J Cancer. 2003 Dec 1;89(11):2019-22 [14647131.001]
  • [Cites] Int J Colorectal Dis. 2004 Mar;19(2):121-3 [12942268.001]
  • [Cites] Cancer. 2004 Apr 1;100(7):1478-83 [15042682.001]
  • [Cites] Melanoma Res. 2004 Apr;14(2):147-50 [15057046.001]
  • [Cites] Oncogene. 2004 May 20;23(23):4060-7 [15048078.001]
  • [Cites] Br J Surg. 2004 Sep;91(9):1183-7 [15449271.001]
  • [Cites] Cancer. 1981 Apr 1;47(7):1891-900 [6164474.001]
  • [Cites] Dis Colon Rectum. 1982 Oct;25(7):693-703 [7128372.001]
  • [Cites] Arch Surg. 1990 Mar;125(3):313-6 [2306178.001]
  • (PMID = 17122627.001).
  • [ISSN] 0003-4932
  • [Journal-full-title] Annals of surgery
  • [ISO-abbreviation] Ann. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1856617
  •  go-up   go-down


54. Penninckx F, D'Hoore A, Vanden Bosch A: [Perineal colostomy with antegrade continence enemas as an alternative after abdominoperineal resection for low rectal cancer]. Ann Chir; 2005 Jun;130(5):327-30
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Perineal colostomy with antegrade continence enemas as an alternative after abdominoperineal resection for low rectal cancer].
  • [Transliterated title] Irrigations coliques antérogrades avec colostomie périnéale comme alternative après résection abdominopérinéale pour cancer du bas rectum.
  • Some young and active patients requiring abdominoperineal resection for rectum cancer ask for an alternative of an abdominal colostomy.
  • A perineal colostomy with ACE seems to be a valuable and less expensive alternative for an abdominal colostomy, and certainly for total anorectal reconstruction.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15935789.001).
  • [ISSN] 0003-3944
  • [Journal-full-title] Annales de chirurgie
  • [ISO-abbreviation] Ann Chir
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


55. Snoj M, Rudolf Z, Cemazar M, Jancar B, Sersa G: Successful sphincter-saving treatment of anorectal malignant melanoma with electrochemotherapy, local excision and adjuvant brachytherapy. Anticancer Drugs; 2005 Mar;16(3):345-8
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful sphincter-saving treatment of anorectal malignant melanoma with electrochemotherapy, local excision and adjuvant brachytherapy.
  • Anorectal malignant melanoma is a rare tumor and there is no consensus on whether aggressive or local management is more appropriate.
  • In our case, a large anorectal malignant melanoma was successfully treated preoperatively by electrochemotherapy with cisplatin that, by reducing the tumor size, enabled sphincter-saving local excision.

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15711188.001).
  • [ISSN] 0959-4973
  • [Journal-full-title] Anti-cancer drugs
  • [ISO-abbreviation] Anticancer Drugs
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; Q20Q21Q62J / Cisplatin
  •  go-up   go-down


56. Füredi G, Szilágyi A, Gilde K, Lövey J, Altorjay A: [Primary anorectal melanoma--an uncommon disease with a poor prognosis]. Magy Seb; 2005 Oct;58(5):337-40
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary anorectal melanoma--an uncommon disease with a poor prognosis].
  • [Transliterated title] Primer anorektális melanoma--egy ritka, de igen rossz prognózisú betegség.
  • Primary anorectal melanoma is a rare disease with poor prognosis.
  • Screening for colorectal cancer may help to detect this disease earlier and the early diagnosis should give better outcome.
  • We present a case report and evaluate--based on literature--epidemiology, most common symptoms, histopathology, diagnosis, treatments and the prognosis of primary anorectal melanomas.
  • [MeSH-minor] Chemotherapy, Adjuvant. Diagnosis, Differential. Humans. Immunotherapy. Male. Middle Aged. Prognosis. Radiotherapy, Adjuvant

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16496780.001).
  • [ISSN] 0025-0295
  • [Journal-full-title] Magyar sebészet
  • [ISO-abbreviation] Magy Seb
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Hungary
  •  go-up   go-down


57. Heemsbergen WD, Hoogeman MS, Hart GA, Lebesque JV, Koper PC: Gastrointestinal toxicity and its relation to dose distributions in the anorectal region of prostate cancer patients treated with radiotherapy. Int J Radiat Oncol Biol Phys; 2005 Mar 15;61(4):1011-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastrointestinal toxicity and its relation to dose distributions in the anorectal region of prostate cancer patients treated with radiotherapy.
  • PURPOSE: To study the correlations between the dose distributions in the anorectal region and late GI symptoms in patients treated for localized prostate carcinoma.
  • The distributions of the anorectal region were projected on maps, and the dose parameters were calculated.
  • Finally, we tested a series of dose parameters originating from different parts of the anorectal region.
  • For bleeding and mucus loss, the strongest correlation was found for the dose received by the upper 70-80% of the anorectal region (p < 0.01).

  • Genetic Alliance. consumer health - Prostate cancer.
  • MedlinePlus Health Information. consumer health - Prostate Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15752880.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Clinical Trial; Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


58. Murad-Regadas SM, Regadas FS, Rodrigues LV, Barreto RG, Monteiro FC, Landim BB, Holanda EC: Role of three-dimensional anorectal ultrasonography in the assessment of rectal cancer after neoadjuvant radiochemotherapy: preliminary results. Surg Endosc; 2009 Jun;23(6):1286-91
MedlinePlus Health Information. consumer health - Cancer Chemotherapy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of three-dimensional anorectal ultrasonography in the assessment of rectal cancer after neoadjuvant radiochemotherapy: preliminary results.
  • BACKGROUND: Three-dimensional anorectal ultrasound (3-DAUS) scanning provides accurate information on tumor size and its relation to the anal muscles.
  • The purpose of this study was to evaluate the ability of 3-DAUS to assess response to radiochemotherapy (RCT) for rectal cancer by comparing 3-DAUS images to pathological findings.
  • [MeSH-minor] Adult. Aged. Disease Progression. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoadjuvant Therapy. Neoplasm Staging / methods. Prospective Studies. Young Adult

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18813985.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


59. Giovannini M, Ardizzone S: Anorectal ultrasound for neoplastic and inflammatory lesions. Best Pract Res Clin Gastroenterol; 2006 Feb;20(1):113-35

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal ultrasound for neoplastic and inflammatory lesions.
  • Although, computed tomography and magnetic resonance imaging are very sensitive in detecting metastatic disease, the local staging of rectal cancer with these techniques has been disappointing.
  • Endorectal ultrasound (ERUS) and anal endosonography (AE) remain the most accurate methods for staging rectal and anal cancer.
  • [MeSH-minor] Humans. Imaging, Three-Dimensional. Neoplasm Staging. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16473804.001).
  • [ISSN] 1521-6918
  • [Journal-full-title] Best practice & research. Clinical gastroenterology
  • [ISO-abbreviation] Best Pract Res Clin Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 85
  •  go-up   go-down


60. Pietrzak L, Bujko K, Nowacki MP, Kepka L, Oledzki J, Rutkowski A, Szmeja J, Kladny J, Dymecki D, Wieczorek A, Pawlak M, Lesniak T, Kowalska T, Richter P, Polish Colorectal Study Group: Quality of life, anorectal and sexual functions after preoperative radiotherapy for rectal cancer: report of a randomised trial. Radiother Oncol; 2007 Sep;84(3):217-25
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quality of life, anorectal and sexual functions after preoperative radiotherapy for rectal cancer: report of a randomised trial.
  • BACKGROUND AND PURPOSE: Patients (N=316) with resectable cT3-4 low-lying and mid-rectal cancer were randomised to receive either preoperative 5x5Gy irradiation with subsequent surgery performed within 7 days or chemoradiation (50.4, 1.8Gy per fraction plus boluses of 5-fluorouracil and leucovorin) followed by surgery after 4-6 weeks.
  • The aim of this report is to find out whether large doses per fraction of short-course schedule result in more severe anorectal and sexual dysfunction and quality of life (QoL) impairment.
  • MATERIALS AND METHOD: Patients who were free of disease were asked to answer the QLQ-C30 and those without stoma were, additionally, asked to fill in a questionnaire of anorectal (19 items) and sexual function (1 item).
  • RESULTS: Two hundred and twenty-two patients (86% response rate) completed the QLQ-C30 and 118 (86% response rate) the anorectal-sexual function questionnaire.
  • The median time from surgery to filling in the QLQ-C30 questionnaire was 12 months, and to filling in the anorectal-sexual function questionnaire - 13 months.
  • We did not find significant differences between the randomised groups regarding QoL and the anorectal and sexual functions.
  • Approximately two-thirds of patients had anorectal function impairment.
  • CONCLUSIONS: QoL and the anorectal and sexual functioning did not differ in patients receiving short-course radiotherapy, as compared to those receiving chemoradiation.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17692977.001).
  • [ISSN] 0167-8140
  • [Journal-full-title] Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • [ISO-abbreviation] Radiother Oncol
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  •  go-up   go-down


61. Böhm G, Kirschner-Hermanns R, Decius A, Heussen N, Schumpelick V, Willis S: Anorectal, bladder, and sexual function in females following colorectal surgery for carcinoma. Int J Colorectal Dis; 2008 Sep;23(9):893-900
MedlinePlus Health Information. consumer health - Sexual Health.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal, bladder, and sexual function in females following colorectal surgery for carcinoma.
  • BACKGROUND: The aim of this study was to establish the incidence of potential postoperative anorectal, bladder, and sexual dysfunction in women following excision of rectal cancer with total mesorectal excision (TME).
  • MATERIALS AND METHODS: All women who underwent a transabdominal rectal resection with TME for cancer between 2000 and 2003 were included.
  • Women with a colonic resection for cancer during the same time period served as the control group.
  • CONCLUSION: After rectal excision, the women showed impairment of their anorectal and sexual function.
  • Our study indicates that women seem to have less functional problems when compared to literature data on dysfunction in male following rectal surgery for cancer.

  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18535831.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


62. Zhou HT, Zhou ZX, Zhang HZ, Bi JJ, Zhao P: Wide local excision could be considered as the initial treatment of primary anorectal malignant melanoma. Chin Med J (Engl); 2010 Mar 5;123(5):585-8
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Wide local excision could be considered as the initial treatment of primary anorectal malignant melanoma.
  • BACKGROUND: Anorectal malignant melanoma was a rare disease with extremely poor prognosis.
  • The aim of this study was to explore the clinical characteristic, diagnosis and treatment strategies of anorectal malignant melanoma.
  • METHODS: The data of 57 patients with anorectal malignant melanoma was collected and retrospectively analyzed.
  • RESULTS: Rectal bleeding and anal mass were found to be common symptoms of anorectal malignant melanoma.
  • The preoperative diagnosis rate of anorectal malignant melanoma was 48.6%.
  • CONCLUSIONS: This study identified no survival advantage to abdominoperineal resection in treatment of anorectal malignant melanoma, and we propose that wide local excision could be considered as the initial treatment of choice.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Survival Rate

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20367986.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  •  go-up   go-down


63. Tezuka K, Inaba Y, Hayashi K, Miura T, Moriya T, Takiguchi M, Isobe H, Watabe S, Yanagawa N: [A case of liver metastasis from anorectal malignant melanoma on hemodialysis treated by chemotherapy]. Gan To Kagaku Ryoho; 2007 Oct;34(10):1709-12
Hazardous Substances Data Bank. DACARBAZINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of liver metastasis from anorectal malignant melanoma on hemodialysis treated by chemotherapy].
  • We report a case on hemodialysis with liver metastases from anorectal malignant melanoma treated by dacarbazine (DTIC).
  • An elastic soft mass was palpated in the anal canal, and a biopsy specimen was diagnosed as anorectal malignant melanoma histologically.
  • Subsequently, the patient died of respiratory failure 4 years after surgery, 1 year and 7 months after the diagnosis of multiple liver metastases.
  • We conclude that administration of DTIC undergoing hemodialysis for malignant melanoma with renal failure seems to be useful without severe adverse events.

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Dialysis.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17940397.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 7GR28W0FJI / Dacarbazine
  •  go-up   go-down


64. Melichar B, Bures J, Dedic K: Anorectal carcinoma after infliximab therapy in Crohn's disease: report of a case. Dis Colon Rectum; 2006 Aug;49(8):1228-33
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal carcinoma after infliximab therapy in Crohn's disease: report of a case.
  • Although therapy with infliximab is generally well tolerated, there is an obvious concern about the effect of this treatment on the incidence of cancer.
  • We report a case of mucinous anorectal adenocarcinoma observed in a 39-year-old patient with long-standing Crohn's disease after therapy with two courses of infliximab.
  • Although there is currently no definitive proof of a causal link between infliximab therapy and cancer, the present observation and other reports in the literature should lead to a careful evaluation of the possibility of increased cancer risk in patients treated with this new agent.
  • [MeSH-minor] Adult. Humans. Infliximab. Male. Neoplasm Recurrence, Local

  • Genetic Alliance. consumer health - Crohn Disease.
  • MedlinePlus Health Information. consumer health - Crohn's Disease.
  • Hazardous Substances Data Bank. Infliximab .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16845561.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; B72HH48FLU / Infliximab
  •  go-up   go-down


65. Bader FG, Bouchard R, Lubienski A, Keller R, Mirow L, Czymek R, Habermann JK, Bruch HP, Roblick UJ: [Progress in diagnostics of anorectal disorders. Part II: radiology]. Chirurg; 2008 May;79(5):410-7
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Progress in diagnostics of anorectal disorders. Part II: radiology].
  • Diagnostics and therapy of anorectal disorders remain a surgical question.
  • The combination of nanotechnology and high-resolution imaging allows precise staging, especially in rectal cancer.
  • [MeSH-major] Anus Neoplasms / diagnosis. Colorectal Neoplasms / diagnosis. Defecography. Image Processing, Computer-Assisted. Imaging, Three-Dimensional. Magnetic Resonance Imaging. Positron-Emission Tomography. Tomography, X-Ray Computed
  • [MeSH-minor] Abscess / diagnosis. Colonic Polyps / diagnosis. Colonography, Computed Tomographic. Humans. Intestinal Obstruction / diagnosis. Rectal Fistula / diagnosis. Sensitivity and Specificity. Whole Body Imaging

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - CT Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] AJR Am J Roentgenol. 1989 May;152(5):999-1003 [2705359.001]
  • [Cites] Radiology. 2008 Mar;246(3):804-11 [18195379.001]
  • [Cites] JAMA. 2004 Apr 14;291(14):1713-9 [15082698.001]
  • [Cites] J Magn Reson Imaging. 2004 Jan;19(1):91-8 [14696225.001]
  • [Cites] Abdom Imaging. 2000 Sep-Oct;25(5):533-41 [10931993.001]
  • [Cites] Endoscopy. 1993 Nov;25(9):582-6 [8119208.001]
  • [Cites] Colorectal Dis. 2004 Jan;6(1):45-53 [14692953.001]
  • [Cites] Int J Colorectal Dis. 2000 Feb;15(1):9-20 [10766086.001]
  • [Cites] Lancet Oncol. 2006 Jan;7(1):52-60 [16389184.001]
  • [Cites] Lancet. 2002 Nov 23;360(9346):1661-2 [12457791.001]
  • [Cites] Radiology. 2006 Apr;239(1):18-33 [16567481.001]
  • [Cites] Dig Dis. 2007;25(1):20-32 [17384505.001]
  • [Cites] Eur J Radiol. 2007 Mar;61(3):462-72 [17145152.001]
  • [Cites] Radiology. 2005 Oct;237(1):123-31 [16100087.001]
  • [Cites] J Gastrointest Surg. 2004 Jan;8(1):73-82; discussion 82 [14746838.001]
  • [Cites] N Engl J Med. 2003 Dec 4;349(23 ):2191-200 [14657426.001]
  • [Cites] J Comput Assist Tomogr. 2004 Jan-Feb;28(1):123-30 [14716245.001]
  • [Cites] Radiology. 2002 May;223(2):501-8 [11997560.001]
  • [Cites] Rofo. 2001 May;173(5):410-5 [11414148.001]
  • [Cites] Eur Radiol. 2004 Jan;14 (1):99-105 [12845463.001]
  • [Cites] Abdom Imaging. 2008 Jan-Feb;33(1):26-30 [17805919.001]
  • [Cites] Radiology. 2004 Apr;231(1):83-90 [14990815.001]
  • [Cites] Clin Cancer Res. 2007 Nov 15;13(22 Pt 2):6877s-84s [18006793.001]
  • [Cites] Radiology. 2007 Aug;244(2):471-8 [17641367.001]
  • [Cites] Br J Surg. 2000 Jan;87(1):10-27 [10606906.001]
  • [Cites] Colorectal Dis. 2001 Jul;3(4):272-5 [12790974.001]
  • [Cites] Dis Colon Rectum. 2001 Jul;44(7):999-1007 [11496081.001]
  • [Cites] Dis Colon Rectum. 1985 Feb;28(2):103-4 [3971802.001]
  • [Cites] Chirurg. 2004 Sep;75(9):850-60 [15258747.001]
  • [Cites] Ann Intern Med. 2005 Apr 19;142(8):635-50 [15838071.001]
  • [Cites] Am J Gastroenterol. 2005 Apr;100(4):808-16 [15784023.001]
  • [Cites] Radiology. 2005 Sep;236(3):886-95 [16014438.001]
  • [Cites] Radiol Clin North Am. 2003 Mar;41(2):425-41 [12659347.001]
  • [Cites] Magn Reson Med Sci. 2005;4(1):11-7 [16127249.001]
  • [Cites] Radiology. 2001 Jan;218(1):75-84 [11152782.001]
  • [Cites] Eur Radiol. 2007 Feb;17 (2):379-89 [17008990.001]
  • [Cites] J Clin Gastroenterol. 2006 Feb;40(2):96-103 [16394868.001]
  • [Cites] Radiology. 2005 Dec;237(3):893-904 [16304111.001]
  • [Cites] Radiology. 2006 Aug;240(2):449-57 [16801366.001]
  • [Cites] J Gastroenterol Hepatol. 2006 Apr;21(4):638-46 [16677147.001]
  • [Cites] World J Gastroenterol. 2007 Jun 21;13(23):3153-8 [17589891.001]
  • [Cites] Radiology. 2002 Sep;224(3):748-56 [12202709.001]
  • [Cites] Digestion. 2007;76(1):34-41 [17947817.001]
  • [Cites] Semin Ultrasound CT MR. 2005 Aug;26(4):259-68 [16152740.001]
  • [Cites] AJR Am J Roentgenol. 1998 Dec;171(6):1607-10 [9843296.001]
  • [Cites] J Magn Reson Imaging. 2000 Feb;11(2):127-35 [10713944.001]
  • [Cites] Chirurg. 2004 Sep;75(9):849 [15258745.001]
  • [Cites] Am J Surg. 2006 Jul;192(1):89-97 [16769283.001]
  • [Cites] N Engl J Med. 1999 Nov 11;341(20):1496-503 [10559450.001]
  • [Cites] Radiographics. 2002 Jul-Aug;22(4):817-32 [12110712.001]
  • [Cites] Eur J Radiol. 2007 Mar;61(3):454-61 [17161573.001]
  • (PMID = 18418564.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 52
  •  go-up   go-down


66. Devroe H, Coene L, Mortelmans LJ, Jutten G: Colloid carcinoma arising in an anorectal fistula in Crohn's disease: a case report. Acta Chir Belg; 2005 Feb;105(1):110-1
MedlinePlus Health Information. consumer health - Crohn's Disease.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colloid carcinoma arising in an anorectal fistula in Crohn's disease: a case report.
  • Carcinoma arising in a chronic anorectal fistula in Crohn's disease is rare, but the association has been reported in the literature.
  • Probably chronic irritation at either end of a fistula can trigger the degeneration of scar tissue into cancer.
  • The diagnosis is difficult, due to lack of specificity of symptoms and signs, and is often delayed, resulting in a poor prognosis.
  • A 70-year-old female, diagnosed with Crohn's disease at the age of 45, developed a pararectal colloid carcinoma in an anorectal fistula that had existed for years.
  • A high index of suspicion and regular surveillance is recommended in chronic anorectal fistulas in Crohn's disease.

  • Genetic Alliance. consumer health - Crohn Disease.
  • MedlinePlus Health Information. consumer health - Anal Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15790217.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
  •  go-up   go-down


67. Iddings DM, Fleisig AJ, Chen SL, Faries MB, Morton DL: Practice patterns and outcomes for anorectal melanoma in the USA, reviewing three decades of treatment: is more extensive surgical resection beneficial in all patients? Ann Surg Oncol; 2010 Jan;17(1):40-4
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Practice patterns and outcomes for anorectal melanoma in the USA, reviewing three decades of treatment: is more extensive surgical resection beneficial in all patients?
  • INTRODUCTION: Historically, the treatment of anorectal melanoma has been abdominoperineal resection (APR), but more recently local resection alone.
  • METHODS: The Surveillance, Epidemiology, and End Results (SEER) database was queried to identify patients treated for anorectal melanoma (1973-2003).
  • CONCLUSION: This study, the largest series to analyze widespread practice patterns and outcomes for anorectal melanoma in the USA, did not reveal a survival difference comparing TAE with APR.

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Surg. 1990 Mar;125(3):313-6 [2306178.001]
  • [Cites] Am J Surg. 2005 Apr;189(4):446-9 [15820458.001]
  • [Cites] Dis Colon Rectum. 1967 May-Jun;10(3):161-76 [6026797.001]
  • [Cites] CA Cancer J Clin. 1966 May-Jun;16(3):111-4 [4957071.001]
  • [Cites] Br J Surg. 2004 Sep;91(9):1183-7 [15449271.001]
  • [Cites] Melanoma Res. 2004 Apr;14(2):147-50 [15057046.001]
  • [Cites] Br J Cancer. 2003 Dec 1;89(11):2019-22 [14647131.001]
  • [Cites] J Am Coll Surg. 2003 Feb;196(2):206-11 [12595048.001]
  • [Cites] J Clin Oncol. 2002 Dec 1;20(23):4555-8 [12454112.001]
  • [Cites] Dis Colon Rectum. 2007 Jul;50(7):1004-10 [17468984.001]
  • [Cites] Ann Surg. 2006 Dec;244(6):1012-7 [17122627.001]
  • [Cites] Dis Colon Rectum. 1982 Oct;25(7):693-703 [7128372.001]
  • [Cites] Cancer. 1998 Oct 15;83(8):1664-78 [9781962.001]
  • [Cites] Dis Colon Rectum. 1995 Feb;38(2):146-51 [7851168.001]
  • [Cites] Am Surg. 2006 Oct;72(10):917-20 [17058735.001]
  • (PMID = 19774417.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA029605-28; United States / NCI NIH HHS / CA / P01 CA029605; United States / NCI NIH HHS / CA / CA29605; United States / NCI NIH HHS / CA / P01 CA029605-28
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS150983; NLM/ PMC2809795
  •  go-up   go-down


68. Ahn KH, Boo YJ, Seol HJ, Park HT, Hong SC, Oh MJ, Kim T, Kim HJ, Kim YT, Kim SH, Lee KW: Prenatally detected congenital perineal mass using 3D ultrasound which was diagnosed as lipoblastoma combined with anorectal malformation: case report. J Korean Med Sci; 2010 Jul;25(7):1093-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prenatally detected congenital perineal mass using 3D ultrasound which was diagnosed as lipoblastoma combined with anorectal malformation: case report.
  • We report a case of prenatally diagnosed congenital perineal mass which was combined with anorectal malformation.
  • This is the first reported case of prenatally diagnosed congenital perineal mass, after birth which was diagnosed as lipoblastoma and even combined with anorectal malformation.
  • This case shows that it can be of clinical importance to be aware of this rare fetal perineal mass in prenatal diagnosis and counseling.
  • [MeSH-minor] Adult. Amniocentesis. Female. Gestational Age. Humans. Infant, Newborn. Male. Pregnancy. Prenatal Diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Surg Oncol. 1986 Aug;32(4):238-44 [3736068.001]
  • [Cites] Hum Pathol. 1985 Jan;16(1):6-18 [2579013.001]
  • [Cites] Histopathology. 1993 Dec;23(6):527-33 [8314236.001]
  • [Cites] Skeletal Radiol. 1994 Jul;23(5):361-7 [7939836.001]
  • [Cites] Semin Diagn Pathol. 1994 May;11(2):98-103 [7809511.001]
  • [Cites] Cancer Genet Cytogenet. 1994 Dec;78(2):232-5 [7828158.001]
  • [Cites] Am J Surg Pathol. 1996 Sep;20(9):1047-55 [8764741.001]
  • [Cites] J Pediatr Surg. 1997 Dec;32(12):1771-2 [9434024.001]
  • [Cites] Diagn Cytopathol. 1999 May;20(5):295-7 [10319231.001]
  • [Cites] Diagn Cytopathol. 2005 Jan;32(1):32-4 [15584040.001]
  • [Cites] J Pediatr Surg. 2005 Jan;40(1):188-91 [15868583.001]
  • [Cites] Pediatr Surg Int. 2005 Oct;21(10):809-12 [16180007.001]
  • [Cites] Prenat Diagn. 2006 Nov;26(11):1065-7 [16952203.001]
  • [Cites] Pediatr Surg Int. 2006 Dec;22(12):979-81 [17001481.001]
  • [Cites] Histopathology. 2002 Jun;40(6):505-9 [12047760.001]
  • [Cites] Cancer. 1973 Aug;32(2):482-92 [4353020.001]
  • [Cites] J Pediatr Surg. 1982 Jun;17(3):277-80 [7108715.001]
  • [Cites] Acta Cytol. 1990 Nov-Dec;34(6):855-7 [1701607.001]
  • (PMID = 20592907.001).
  • [ISSN] 1598-6357
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2890892
  • [Keywords] NOTNLM ; Anal Canal / Congenital Abnormalities / Lipoblastoma / Perineum / Prenatal Diagnosis
  •  go-up   go-down


69. Eum EA, Kim H, Kim YM, Woo SJ, Cho JH, Min YJ, Park JH: Anorectal and gastric peripheral T-cell lymphoma, unspecified in a non-AIDS patient. Korean J Intern Med; 2006 Dec;21(4):262-5
HIV InSite. treatment guidelines - Human Herpesvirus-8 .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal and gastric peripheral T-cell lymphoma, unspecified in a non-AIDS patient.
  • Anorectum is a rare location for malignant lymphoma.
  • Involvement of is rare even for the lynphoma associated with acquired immune deficiency syndrome (AIDS), and AIDS has a relatively increased frequency of anorectal lymphoma.
  • We report here on a case of anorectal and gastric peripheral T-cell lymphoma, unspecified (PTCLu) in a non-AIDS patient.
  • He underwent excisional biopsy for the anal mass and the diagnosis was PTCLu.
  • Biopsies of the gastric lesions gave the same diagnosis.
  • [MeSH-major] Acquired Immunodeficiency Syndrome / diagnosis. Lymphoma, T-Cell, Peripheral / pathology. Rectal Neoplasms / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Follow-Up Studies. Gastroscopy. Humans. Male. Sigmoidoscopy. Tomography, X-Ray Computed


70. Sasaki S, Kojima T, Hidemura A, Hatanaka K, Uekusa T, Ishimaru M: [A case report of anorectal malignant melanoma showing a complete response after DTIC/ACNU/VCR therapy]. Gan To Kagaku Ryoho; 2010 Oct;37(10):1999-2002
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case report of anorectal malignant melanoma showing a complete response after DTIC/ACNU/VCR therapy].
  • The patient was diagnosed with malignant melanoma of the anorectum using colonoscopy.
  • Cancer cells were found in regional lymph nodes.
  • However, malignant melanoma cells were found in hernia contents at the operation for left inguinal hernia, which led to a diagnosis of recurrent malignant melanoma.
  • To our knowledge, this is the first report of a complete response in a patient with multiple liver metastases of anorectal malignant melanoma after DAV regimen.

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • Hazardous Substances Data Bank. DACARBAZINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20948273.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0S726V972K / Nimustine; 5J49Q6B70F / Vincristine; 7GR28W0FJI / Dacarbazine
  •  go-up   go-down


71. Tomita R, Igarashi S: A pathophysiological study using anorectal manometry on patients with or without soiling 5 years or more after low anterior resection for lower rectal cancer. Hepatogastroenterology; 2008 Sep-Oct;55(86-87):1584-8
Genetic Alliance. consumer health - Rectal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A pathophysiological study using anorectal manometry on patients with or without soiling 5 years or more after low anterior resection for lower rectal cancer.
  • BACKGROUND/AIMS: Physiological assessments of the anorectum in patients with soiling 5 years or more after low anterior resection (LAR) are still inconclusive.
  • The purpose of this study is to clarify the significance of anorectal functions in patients with soiling 5 years or more after LAR for lowerrectal cancer.
  • METHODOLOGY: Thirty-eight patients after LAR for lower rectal cancer were manometrically studied and compared with 30 healthy volunteers as controls (group C; 19 men and 11 women, aged 44 to 76 with a mean age of 65.5 years).
  • Anorectal manometry was performed on all patients in order to assess: Anal sphincter pressure at rest (ASPR; mmHg), Maximum anal sphincter pressure during voluntary contraction (MASPVC; mmHg), Minimum rectal sensory threshold volume (MRSTV; mL), Maximum rectal tolelated threshold volume (MRTTV; mL), Rectal compliance (RC; mL/mmHg), Rectoanal inhibitory reflex (RAIR), and Rectal pressure (RP; mmHg).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19102347.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


72. Zhong J, Zhou JN, Xu FP, Shang JQ: [Diagnosis and treatment of anorectal malignant melanoma--a report of 22 cases with literature review]. Ai Zheng; 2006 May;25(5):619-24
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis and treatment of anorectal malignant melanoma--a report of 22 cases with literature review].
  • BACKGROUND & OBJECTIVE: Anorectal malignant melanoma (AMM) is an aggressive malignant tumor, and its treatment still remains controversial.
  • This study was to summarize our experience on diagnosis and treatment of AMM.
  • METHODS: Clinicopathologic records, including clinical feature, diagnosis, operation patterns, and prognosis, of 22 patients with AMM, treated in Jiangsu Provincial Cancer Hospital from 1977 to 2003, were analyzed retrospectively with literature review.
  • RESULTS: The 22 patients with AMM accounted for 0.04% of all the patients diagnosed as malignant tumors of large bowel simultaneously in our hospital.
  • The definite pathologic diagnosis rate before surgery was 48%.
  • [MeSH-major] Anus Neoplasms / diagnosis. Anus Neoplasms / surgery. Melanoma / diagnosis. Melanoma / surgery. Rectal Neoplasms / diagnosis. Rectal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Anal Canal / surgery. Antigens, Neoplasm / metabolism. Chemotherapy, Adjuvant. Colostomy. Diagnostic Errors. Female. Follow-Up Studies. Hemorrhoids / diagnosis. Humans. Liver Neoplasms / secondary. Male. Melanoma-Specific Antigens. Middle Aged. Neoplasm Proteins / metabolism. Neoplasm Recurrence, Local. Prognosis. Radiotherapy, Adjuvant. Rectum / surgery. Retrospective Studies. Survival Rate

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16687086.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
  • [Number-of-references] 13
  •  go-up   go-down


73. Stoidis CN, Spyropoulos BG, Misiakos EP, Fountzilas CK, Paraskeva PP, Fotiadis CI: Diffuse anorectal melanoma; review of the current diagnostic and treatment aspects based on a case report. World J Surg Oncol; 2009;7:64
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diffuse anorectal melanoma; review of the current diagnostic and treatment aspects based on a case report.
  • Primary anorectal melanoma is a rare and aggressive disease.
  • [MeSH-major] Anus Neoplasms / diagnosis. Melanoma / diagnosis

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br J Surg. 2001 Jul;88(7):994-1000 [11442534.001]
  • [Cites] Am Surg. 2001 Nov;67(11):1048-58 [11730221.001]
  • [Cites] Melanoma Res. 2002 Aug;12(4):395-8 [12170190.001]
  • [Cites] J Clin Oncol. 2002 Dec 1;20(23):4555-8 [12454112.001]
  • [Cites] Can J Surg. 2003 Oct;46(5):345-9 [14577706.001]
  • [Cites] Br J Cancer. 2003 Dec 1;89(11):2019-22 [14647131.001]
  • [Cites] Cancer. 2004 Apr 1;100(7):1478-83 [15042682.001]
  • [Cites] Melanoma Res. 2004 Apr;14(2):147-50 [15057046.001]
  • [Cites] Pathologe. 2004 May;25(3):171-7 [15138698.001]
  • [Cites] Cancer. 1998 Oct 15;83(8):1664-78 [9781962.001]
  • [Cites] Cancer. 1999 Apr 15;85(8):1686-93 [10223561.001]
  • [Cites] Tech Coloproctol. 2005 Apr;9(1):60-2 [15868503.001]
  • [Cites] Lancet Oncol. 2005 Jun;6(6):438-9 [15925823.001]
  • [Cites] Eur J Surg Oncol. 2005 Sep;31(7):735-42 [16180267.001]
  • [Cites] Am Surg. 2006 Oct;72(10):917-20 [17058735.001]
  • [Cites] Ann Surg. 2006 Dec;244(6):1012-7 [17122627.001]
  • [Cites] Colorectal Dis. 2008 Jul;10(6):612-5 [17944970.001]
  • [Cites] Int J Colorectal Dis. 2008 Dec;23(12):1257-62 [18633625.001]
  • (PMID = 19671138.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2731760
  •  go-up   go-down


74. Peralta EA: Rare anorectal neoplasms: gastrointestinal stromal tumor, carcinoid, and lymphoma. Clin Colon Rectal Surg; 2009 May;22(2):107-14
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rare anorectal neoplasms: gastrointestinal stromal tumor, carcinoid, and lymphoma.
  • Increased clinical experience and advancements in molecular biology have improved the accuracy of pathologic diagnosis and guided treatment recommendations, which the author addresses in this article.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Surg Pathol. 1999 Aug;23(8):946-54 [10435565.001]
  • [Cites] Cancer. 1971 Jul;28(1):175-80 [5110628.001]
  • [Cites] World J Surg. 2000 Apr;24(4):437-43 [10706916.001]
  • [Cites] Mod Pathol. 2001 Oct;14(10):950-6 [11598163.001]
  • [Cites] Am J Surg Pathol. 2001 Sep;25(9):1121-33 [11688571.001]
  • [Cites] Hum Pathol. 2002 May;33(5):459-65 [12094370.001]
  • [Cites] N Engl J Med. 2002 Aug 15;347(7):472-80 [12181401.001]
  • [Cites] AJR Am J Roentgenol. 2003 Jun;180(6):1607-12 [12760929.001]
  • [Cites] Am J Surg. 1964 Jun;107:844-9 [14169012.001]
  • [Cites] Ann Surg Oncol. 2004 May;11(5):465-75 [15123459.001]
  • [Cites] Dis Colon Rectum. 2004 Nov;47(11):1922-9 [15622586.001]
  • [Cites] Cancer. 2005 Apr 15;103(8):1587-95 [15742328.001]
  • [Cites] Dis Colon Rectum. 1992 Apr;35(4):328-31 [1582353.001]
  • [Cites] Hum Pathol. 1992 Jul;23(7):762-7 [1612575.001]
  • [Cites] Cancer. 2006 Jan 1;106(1):128-35 [16329140.001]
  • [Cites] Dis Colon Rectum. 1992 Aug;35(8):717-25 [1643994.001]
  • [Cites] Dis Colon Rectum. 2006 May;49(5):609-15 [16552495.001]
  • [Cites] Lancet. 2006 Oct 14;368(9544):1329-38 [17046465.001]
  • [Cites] Arch Pathol Lab Med. 2006 Oct;130(10):1466-78 [17090188.001]
  • [Cites] World J Surg Oncol. 2007;5:20 [17306018.001]
  • [Cites] Surg Today. 2007;37(6):455-9 [17522761.001]
  • [Cites] J Natl Compr Canc Netw. 2007 Jul;5 Suppl 2:S1-29; quiz S30 [17624289.001]
  • [Cites] Cancer. 2008 Feb 1;112(3):608-15 [18076015.001]
  • [Cites] J Surg Oncol. 2008 Mar 15;97(4):350-9 [18286477.001]
  • [Cites] J Surg Oncol. 2009 Jan 1;99(1):42-7 [18942073.001]
  • [Cites] Br J Surg. 1984 Aug;71(8):597-9 [6743978.001]
  • [Cites] Cancer. 1997 Apr 1;79(7):1294-8 [9083149.001]
  • [Cites] Am J Surg Pathol. 1997 Sep;21(9):997-1006 [9298875.001]
  • [Cites] Science. 1998 Jan 23;279(5350):577-80 [9438854.001]
  • [Cites] Am J Pathol. 1998 May;152(5):1259-69 [9588894.001]
  • [Cites] J Surg Oncol. 2006 Mar 15;93(4):304-11 [16496358.001]
  • [Cites] Ann Surg Oncol. 2007 Feb;14(2):396-404 [17094024.001]
  • [Cites] Indian J Gastroenterol. 2007 Jan-Feb;26(1):33-5 [17401234.001]
  • [Cites] Nat Clin Pract Oncol. 2008 May;5(5):240-1 [18349856.001]
  • [Cites] Arch Surg. 2008 May;143(5):471-5 [18490556.001]
  • [Cites] Surgery. 2008 Sep;144(3):460-6 [18707046.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2194-201 [18708414.001]
  • [Cites] Z Gastroenterol. 2008 Aug;46(8):760-5 [18759198.001]
  • [Cites] Oncologist. 2008 Dec;13(12):1255-69 [19091780.001]
  • [Cites] Dis Colon Rectum. 1997 Sep;40(9):1101-18 [9293943.001]
  • [Cites] Histopathology. 1988 Mar;12(3):235-52 [3366441.001]
  • [Cites] Ann Surg. 2000 Jan;231(1):51-8 [10636102.001]
  • (PMID = 20436835.001).
  • [ISSN] 1530-9681
  • [Journal-full-title] Clinics in colon and rectal surgery
  • [ISO-abbreviation] Clin Colon Rectal Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2780247
  • [Keywords] NOTNLM ; Gastrointestinal stromal tumors / carcinoid / lymphoma
  •  go-up   go-down


75. Mittal R, Perakath B, Chase S, Jesudason MR, Nayak S: Transanal excision of anorectal lesions--a single centre experience. Trop Gastroenterol; 2010 Jan-Mar;31(1):65-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transanal excision of anorectal lesions--a single centre experience.
  • BACKGROUND: Transanal excision is commonly used to treat lesions of the anorectum.
  • Patients were divided into three groups. (1) Resection for benign disease (2) Curative and (3) Palliative resection for malignant disease.
  • RESULTS: Forty six patients underwent transanal excision, 21 for benign and 25 for malignant disease, 20 with curative and 5 with palliative intent.
  • Four patients with malignant melanoma and one with adenocarcinoma underwent palliative resection.
  • It offers good palliation of local symptoms in advanced malignant disease.
  • It can be used in a carefully selected group of patients with early rectal cancer.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Anal Canal / surgery. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Palliative Care. Postoperative Complications. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20860237.001).
  • [ISSN] 0250-636X
  • [Journal-full-title] Tropical gastroenterology : official journal of the Digestive Diseases Foundation
  • [ISO-abbreviation] Trop Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  •  go-up   go-down


76. Cha JM, Choi SI, Lee JI: Rectal syphilis mimicking rectal cancer. Yonsei Med J; 2010 Mar;51(2):276-8
MedlinePlus Health Information. consumer health - Syphilis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rectal syphilis mimicking rectal cancer.
  • Gastroenterologists should be aware of the possibility of rectal syphilis when confronted with anorectal ulcers, and should gather a detailed history about sexual preferences and practices, including homosexuality.
  • We report a case of primary rectal syphilis mimicking rectal cancer on radiologic imaging.
  • [MeSH-major] Rectal Diseases / diagnosis. Rectal Neoplasms / pathology. Syphilis / diagnosis

  • Genetic Alliance. consumer health - Rectal Cancer.
  • MedlinePlus Health Information. consumer health - Rectal Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Sex Transm Infect. 2005 Dec;81(6):448-52 [16326843.001]
  • [Cites] J Korean Med Sci. 2005 Oct;20(5):886-7 [16224168.001]
  • [Cites] Dis Colon Rectum. 1968 Nov;11(6):462-6 [5749286.001]
  • [Cites] Ann Surg. 1976 Jul;184(1):65-7 [938119.001]
  • [Cites] Am J Dig Dis. 1977 Aug;22(8):701-4 [879137.001]
  • [Cites] Sem Hop. 1981 Sep 18-25;57(33-36):1434-8 [6270807.001]
  • [Cites] Gastroenterology. 1982 Jan;82(1):135-9 [7030863.001]
  • [Cites] Gut. 1981 Dec;22(12):1035-41 [6895627.001]
  • [Cites] Am J Clin Pathol. 1983 Nov;80(5):719-21 [6356872.001]
  • [Cites] Gastroenterology. 1986 Sep;91(3):651-9 [3755414.001]
  • [Cites] Genitourin Med. 1989 Jan;65(1):1-3 [2921046.001]
  • [Cites] Clin Lab Med. 1989 Sep;9(3):545-57 [2676323.001]
  • [Cites] Dis Colon Rectum. 1990 Dec;33(12):1048-62 [2242700.001]
  • [Cites] Dis Colon Rectum. 1991 Nov;34(11):1024-6 [1935467.001]
  • [Cites] Sex Transm Infect. 2004 Dec;80(6):451-4 [15572612.001]
  • [Cites] Euro Surveill. 2004 Dec;9(12):21-5 [15677851.001]
  • [Cites] Postgrad Med J. 2006 Nov;82(973):733-6 [17099092.001]
  • (PMID = 20191023.001).
  • [ISSN] 1976-2437
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2824876
  • [Keywords] NOTNLM ; Rectum / Treponema pallidum / chancre / syphilis / ulcer
  •  go-up   go-down


77. Moriya Y: [Selection and techniques of surgical procedures based on the mode of cancer spread of rectal cancer]. Nihon Geka Gakkai Zasshi; 2005 Apr;106(4):302-5
Genetic Alliance. consumer health - Rectal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Selection and techniques of surgical procedures based on the mode of cancer spread of rectal cancer].
  • The author reviewed recent results of Japanese and international studies on preoperative staging, pathology of bisopied specimens, sentinel node navigation surgery, and single tumor cells in rectal cancer.
  • Examination of circumferential resection margins is incompatible with that of lymph nodes Intersphincteric resection can be an alternative to abdominoperineal resection for selected rectal tumors located at the anorectal junction without compromising the chance for cure.
  • We emphasize that multiinstitutional clinical trials of adjuvant chemoradiotherapy and surgical treatment are indispensable for developing treatments for rectal cancer in Japan.
  • [MeSH-minor] Digestive System Surgical Procedures / methods. Humans. Neoplasm Metastasis / pathology. Neoplasm Staging. Sentinel Lymph Node Biopsy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15859142.001).
  • [ISSN] 0301-4894
  • [Journal-full-title] Nihon Geka Gakkai zasshi
  • [ISO-abbreviation] Nihon Geka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 14
  •  go-up   go-down


78. Ikeuchi H, Nakano H, Uchino M, Nakamura M, Matsuoka H, Fukuda Y, Matsumoto T, Takesue Y, Tomita N: Intestinal cancer in Crohn's disease. Hepatogastroenterology; 2008 Nov-Dec;55(88):2121-4
MedlinePlus Health Information. consumer health - Crohn's Disease.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intestinal cancer in Crohn's disease.
  • AIMS: We investigated Crohn's Disease (CD) patients with carcinomas in the intestinal tract to emphasize the difficulty in establishing a diagnosis, as well as show the importance of establishing formal guidelines for screening and surveillance of cancers associated with perianal CD.
  • RESULTS: In 9 of the patients, carcinomas developed in relation to CD, 7 of whom had cancer of the lower rectum and anus with severe anorectal CD lesions.
  • Five of 6 patients with advanced carcinoma in the anorectal region were treated using preoperative chemoradiation therapy and all 7 with anorectal carcinomas underwent an abdominoperineal resection.
  • Two patients with a carcinoma of the fistula in the ileo-rectum or ileo-sigmoid colon were treated by a partial resection of the small and large bowel with the fistula.
  • It is important to establish a surveillance program for CD patients, especially those complicated with severe anorectal CD lesions.

  • Genetic Alliance. consumer health - Crohn Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19260489.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


79. Yao H, Jin HY, Wu KL, Zhang JH, Zhang P, Wang XF, Cui DX, Ding YJ: [Impact of polyamidoamine dendrimer liposome on the cellular uptake and cytotoxicity of colonic cancer cells]. Zhonghua Wai Ke Za Zhi; 2010 Dec 1;48(23):1815-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Impact of polyamidoamine dendrimer liposome on the cellular uptake and cytotoxicity of colonic cancer cells].
  • OBJECTIVE: To evaluate the effects of polyamidoamine dendrimer (PAMAM) liposome as gene carriers on the cellular uptake and its cytotoxicity in colonic cancer cell.
  • After the cell lines SW620 (colonic cancer cell), MCF-7 (breast cancer cell), ECV304 (vascular endothelial cell) were transfected by the two kinds of PAMAM nanoparticle complexes, the flow cytometry was used to determine the uptake of enhanced green fluorescent protein (EGFP) gene.
  • After the colonic cancer cell line SW620 was transfected with the two kinds of PAMAM nanoparticle complexes, the cellular uptake of the cells with the liposome-modified PAMAM complex was significantly higher than that of the cell with PAMAM complex (P < 0.05).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21211388.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Dendrimers; 0 / Liposomes
  •  go-up   go-down


80. Kusunoki M, Inoue Y: Current surgical management of rectal cancer. Dig Surg; 2007;24(2):115-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Current surgical management of rectal cancer.
  • The management of rectal cancer has undergone significant evolution over the past decade with improvements in both surgical technique and adjuvant therapies.
  • The major goals of surgery are to optimize oncologic outcome and maintain anorectal and genitourinary function.
  • There are presently two approaches to rectal cancer surgery: total mesorectal excision (TME), which is the gold standard in the Western world, and lateral lymph node dissection, which was originally developed in Japan.
  • Despite the current quality of these surgical procedures, locoregional treatment is limited as advanced primary rectal cancer may be associated with systemic spread of disease.
  • In this article, evidence for the use and benefits of lateral lymph node dissection surgery for rectal cancer patients in Japan is reviewed, and its application in association with TME and other modalities considered.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 S. Karger AG, Basel.
  • (PMID = 17446705.001).
  • [ISSN] 0253-4886
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 37
  •  go-up   go-down


81. Ceelen W, Pattyn P, Boterberg T, Peeters M: Pre-operative combined modality therapy in the management of locally advanced rectal cancer. Eur J Surg Oncol; 2006 Apr;32(3):259-68
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pre-operative combined modality therapy in the management of locally advanced rectal cancer.
  • AIMS: To review the use of pre-operative combined modality therapy (CMT, chemotherapy with radiotherapy) in the management of resectable rectal cancer.
  • METHODS: A systematic search was performed on pre-operative CMT and rectal cancer.
  • The scarce available data suggest that the addition of CT might worsen anorectal function compared to pre-operative RT alone.
  • CONCLUSIONS: Pre-operative CMT enhances tumour response and could therefore, have a role in patients with possibly invaded resection margins or low lying cancers, although both acute toxicity and anorectal function are worse compared to RT alone.
  • The final results of ongoing randomized trials will more accurately establish the role of pre-operative CMT in resectable rectal cancer patients.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16443345.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 120
  •  go-up   go-down


82. Miyamoto H, Nishioka M, Kurita N, Nakagawa T, Yoshikawa K, Higashijima J, Miyatani T, Shimada M: Usefulness of local excision for early lower rectal cancer. Hepatogastroenterology; 2007 Apr-May;54(75):736-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Usefulness of local excision for early lower rectal cancer.
  • BACKGROUND/AIMS: The purpose of this study was to examine the long-term results of transanal excision compared with major surgery for lower rectal cancer.
  • METHODOLOGY: This retrospective study included 14 patients with early rectal cancer within 8cm from the anal verge treated by local excision in the period from January 1991 to December 2000, and 16 patients treated by major surgery in the period from January 1996 to December 2000.
  • We evaluated the prognosis or anorectal or urinary function of these patients.
  • Anorectal and urinary function maintained a good status.
  • CONCLUSIONS: Local excision for early rectal cancer (Tis N0 M0) brought an excellent outcome, and maintained good anorectal and urinary function.
  • We recommend local excision for the early rectal cancer patients.
  • [MeSH-minor] Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Treatment Outcome

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17591051.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  •  go-up   go-down


83. Qin H, Zhang XP, Zhou Y, Li HC, Li T: [Experience of laparoscopic total mesorectal excision for middle or low rectal cancer]. Zhonghua Zhong Liu Za Zhi; 2010 Feb;32(2):156-7
Genetic Alliance. consumer health - Rectal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Experience of laparoscopic total mesorectal excision for middle or low rectal cancer].
  • OBJECTIVE: To study the feasibility and safety of laparoscopic surgery for middle or low rectal cancer.
  • METHODS: 83 patients with middle or low rectal cancer received laparoscopic surgery and 85 patients received conventional open surgery.
  • CONCLUSION: Laparoscopic surgery is a safe and effective procedure for middle or low rectal cancer, with less postoperative complications and better recovery after treatment.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Digestive System Surgical Procedures / methods. Female. Humans. Lymph Node Excision. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Postoperative Complications. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20403250.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
  •  go-up   go-down


84. Sarli L, Pavlidis C, Cinieri FG, Regina G, Sansebastiano G, Veronesi L, Ferro M, Morari S, Violi V, Roncoroni L: Prospective comparison of laparoscopic left hemicolectomy for colon cancer with laparoscopic left hemicolectomy for benign colorectal disease. World J Surg; 2006 Mar;30(3):446-52
MedlinePlus Health Information. consumer health - Diverticulosis and Diverticulitis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prospective comparison of laparoscopic left hemicolectomy for colon cancer with laparoscopic left hemicolectomy for benign colorectal disease.
  • BACKGROUND: Short-term outcome and anorectal function results after laparoscopic hemicolectomy for colon cancer were compared with results after laparoscopic hemicolectomy for benign diseases.
  • METHODS: A total of 108 patients who underwent laparoscopic left colectomy (60 for colon cancer, 48 for diverticulitis or polyposis) were enrolled in the study.
  • Left hemicolectomy in patients affected by cancer was performed by high ligation of the inferior mesenteric artery.
  • A questionnaire concerning anorectal function was mailed to patients 6 months after surgery.
  • RESULTS: Complications were more frequent in the cancer group than in the benign disease group: overall morbidity rate (29.6% versus 8.7%; P = 0.009), diarrhea during the first 6 postoperative months (58.7% versus 34.1%; P = 0.022), and anorectal function problems (fecal incontinence and/or the inability to discriminate between gas and stool, and/or urgency, and/or tenesmus) (65.2% versus 31.7%; P = 0.002).
  • DISCUSSION: The level of ligation of the lower mesenteric artery and damage at the lower mesenteric ganglion could explain the poorer anorectal function outcome in the colon cancer group.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colonic Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16479334.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


85. Yamada K, Ogata S, Saiki Y, Fukunaga M, Tsuji Y, Takano M: Functional results of intersphincteric resection for low rectal cancer. Br J Surg; 2007 Oct;94(10):1272-7
Genetic Alliance. consumer health - Rectal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Functional results of intersphincteric resection for low rectal cancer.
  • BACKGROUND: Intersphincteric resection (ISR) is the ultimate sphincter-preserving operation for very low rectal cancer.
  • METHODS: Between 2001 and 2003, 35 consecutive patients with low rectal cancer had curative ISR, categorized as total, subtotal or partial resection of the internal anal sphincter.
  • Sphincter function was evaluated by manometric study and anorectal sensation testing before surgery and 3, 6 and 12 months afterwards.
  • CONCLUSION: These functional results suggest that ISR should be considered as an alternative to abdominoperineal resection for low rectal cancer.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2007 British Journal of Surgery Society Ltd.
  • [CommentIn] Br J Surg. 2008 Mar;95(3):397; author reply 397-8 [18278786.001]
  • (PMID = 17671960.001).
  • [ISSN] 1365-2168
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


86. Shelygin YA, Vorobiev GI, Pikunov DY, Markova EV, Djhanaev YA, Fomenko OY: Intersphincteric resection with partial removal of external anal sphincter for low rectal cancer. Acta Chir Iugosl; 2008;55(3):45-53
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intersphincteric resection with partial removal of external anal sphincter for low rectal cancer.
  • Abdominoperineal resection (APR) remains the standard procedure for rectal cancer located within 0.5 cm from dentate line (DL).
  • In this study, we present a new type of restorative surgery: intersphincteric resection with partial removal of external anal sphincter (EAS) and anorectal reconstruction for-ultra low rectal cancer.
  • Between March 2003 and May 2008 fifty patients (28 males, aged between 39 and 71) were operated on for ultra low rectal cancer uT2-3N0M0 with partial preservation of EAS and total anorectal reconstruction (smooth-muscle neosphincter and colonic pouch).

  • Genetic Alliance. consumer health - Anal Cancer.
  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19069692.001).
  • [ISSN] 0354-950X
  • [Journal-full-title] Acta chirurgica Iugoslavica
  • [ISO-abbreviation] Acta Chir Iugosl
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Serbia
  •  go-up   go-down


87. Jeong SY, Chessin DB, Guillem JG: Surgical treatment of rectal cancer: radical resection. Surg Oncol Clin N Am; 2006 Jan;15(1):95-107, vi-vii
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of rectal cancer: radical resection.
  • Currently, surgery is the only potentially curative treatment modality for rectal cancer.
  • The major goals of surgery for rectal cancer are to optimize oncologic outcome and maintain anorectal and genitourinary function.
  • This article reviews the surgical management of primary rectal cancer and discusses major surgical considerations in the treatment of this disease.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16389152.001).
  • [ISSN] 1055-3207
  • [Journal-full-title] Surgical oncology clinics of North America
  • [ISO-abbreviation] Surg. Oncol. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 79
  •  go-up   go-down


88. Canda AE, Terzi C, Gorken IB, Oztop I, Sokmen S, Fuzun M: Effects of preoperative chemoradiotherapy on anal sphincter functions and quality of life in rectal cancer patients. Int J Colorectal Dis; 2010 Feb;25(2):197-204
Hazardous Substances Data Bank. FLUOROURACIL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effects of preoperative chemoradiotherapy on anal sphincter functions and quality of life in rectal cancer patients.
  • PURPOSE: Deterioration of anorectal function after long-course preoperative chemoradiotherapy combined with surgery for rectal cancer is poorly defined.
  • We conducted a prospective study to evaluate the acute and long term effects of preoperative chemoradiotherapy on anorectal function and quality of life of the patients.
  • Anorectal function and quality of life of the patients were assessed by anorectal manometry, incontinence score, quality of life questionnaire.
  • CONCLUSIONS: Both total mesorectal excision and preoperative chemoradiotherapy may adversely affect the anorectal function.
  • Careful selection of the patients who will benefit from neoadjuvant therapy and identifying the patients with a high risk of developing functional problems may help to improve functional outcomes for the treatment of rectal cancer.

  • Genetic Alliance. consumer health - Anal Cancer.
  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19784660.001).
  • [ISSN] 1432-1262
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; U3P01618RT / Fluorouracil
  •  go-up   go-down


89. Wang JP, Wu XJ, Song XM, Wang L, Huang MJ, Lan P: [Changes of sphincter preserving rate in lower rectal cancer and analysis of their related factors]. Zhonghua Wei Chang Wai Ke Za Zhi; 2006 Mar;9(2):107-10
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Changes of sphincter preserving rate in lower rectal cancer and analysis of their related factors].
  • OBJECTIVE: To analyze the factors related to sphincter preserving(SP) operation for lower rectal cancer.
  • METHODS: Clinicopathological data of 316 patients with lower rectal cancer 1-5 cm from the anorectal line who underwent surgical resection from Aug.
  • The factors significantly influencing SP were the distance from the anorectal line, sex, period, circumference of intramural spread, histological differentiation (P< 0.05).
  • CONCLUSIONS: Over 12 years, the SP rate of rectal cancers 1-5 cm from the anorectal line was significantly increased and volume of blood transfusion reduced obviously due to the introduction of TME.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16555145.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


90. Badin S, Iqbal A, Sikder M, Chang VT: Persistent pain in anal cancer survivors. J Cancer Surviv; 2008 Jun;2(2):79-83
MedlinePlus Health Information. consumer health - Pain.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Persistent pain in anal cancer survivors.
  • INTRODUCTION: Anorectal cancers are highly curable malignancies.
  • IMPLICATIONS FOR CANCER SURVIVORS: Treatment related lumbosacral plexopathy may be an unrecognized consequence of the successful treatment of anal carcinoma.

  • Genetic Alliance. consumer health - Anal Cancer.
  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18648976.001).
  • [ISSN] 1932-2267
  • [Journal-full-title] Journal of cancer survivorship : research and practice
  • [ISO-abbreviation] J Cancer Surviv
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


91. Du P, Zi SM, Weng ZY, Chen W, Chen Y, Cui L: [Biofeedback therapy for fecal incontinence in patients with mid or low rectal cancer after restorative resection]. Zhonghua Wei Chang Wai Ke Za Zhi; 2010 Aug;13(8):580-2
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Biofeedback therapy for fecal incontinence in patients with mid or low rectal cancer after restorative resection].
  • OBJECTIVE: To investigate the efficacy of biofeedback therapy for fecal incontinence in patients with mid or low rectal cancer.
  • METHODS: Twenty-four patients with mid or low rectal cancer received biofeedback treatments after restorative resection and therapeutic efficacy was evaluated using anorectal manometry and Vaizey and Wexner scoring systems.
  • RESULTS: The parameters of anorectal manometry in patients with rectal cancer were significantly lower than those in the control group (P<0.01).
  • CONCLUSION: Biofeedback therapy can improve the anal function in patients with rectal cancer after restorative resection.

  • Genetic Alliance. consumer health - Incontinence.
  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20737308.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
  •  go-up   go-down


92. Glynne-Jones R, Mawdsley S: Anal cancer: is neoadjuvant cisplatin chemotherapy or chemoradiotherapy friend or foe? Nat Clin Pract Oncol; 2008 Dec;5(12):692-3
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anal cancer: is neoadjuvant cisplatin chemotherapy or chemoradiotherapy friend or foe?
  • Although chemoradiotherapy has had an important effect on the treatment of anal cancer, and allows preservation of anorectal function with survival rates similar to or better than those of surgical treatment, overall survival rates for advanced tumors are still in the region of 50-60% at 5 years.
  • A strong theoretical rationale for cisplatin-based treatment in anal cancer exists; several phase II trials have demonstrated a high response rate with reduced colostomy rates.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18852720.001).
  • [ISSN] 1743-4262
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


93. Lim JF, Tjandra JJ, Hiscock R, Chao MW, Gibbs P: Preoperative chemoradiation for rectal cancer causes prolonged pudendal nerve terminal motor latency. Dis Colon Rectum; 2006 Jan;49(1):12-9
Hazardous Substances Data Bank. LEUCOVORIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative chemoradiation for rectal cancer causes prolonged pudendal nerve terminal motor latency.
  • PURPOSE: A worsened anorectal function after chemoradiation for high-risk rectal cancer is often attributed to radiation damage of the anorectum and pelvic floor.
  • This prospective study evaluated the short-term effect of preoperative combined chemoradiation on anorectal physiologic and pudendal nerve function.
  • METHODS: Sixty-six patients (39 men, 27 women) with localized resectable (T3, T4, or N1) rectal cancer were included in the study.
  • Patients who had rectal cancer with a distal margin within 6 cm of the anal verge had the anus included in the field of radiotherapy (Group A, n = 26).
  • Patients who had rectal cancer with a distal margin 6 to 12 cm from the anal verge had shielding of the anus during radiotherapy (Group B, n = 40).
  • The Wexner continence score, anorectal manometry and pudendal nerve terminal motor latency were assessed at baseline and four weeks after completion of chemoradiation.
  • CONCLUSIONS: Preoperative chemoradiation for rectal cancer carries a significant risk of pudendal neuropathy, which might contribute to the incidence of fecal incontinence after restorative proctectomy for rectal cancer.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • MedlinePlus Health Information. consumer health - Peripheral Nerve Disorders.
  • Hazardous Substances Data Bank. FLUOROURACIL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16292664.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 12001-76-2 / Vitamin B Complex; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
  •  go-up   go-down


94. Valentini V, Barba MC, Gambacorta MA: The role of multimodality treatment in M0 rectal cancer: evidence and research. Eur Rev Med Pharmacol Sci; 2010 Apr;14(4):334-41
Genetic Alliance. consumer health - Rectal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of multimodality treatment in M0 rectal cancer: evidence and research.
  • In the last two decades we have seen major advances in the strategy of the treatment of rectal cancer.
  • Many studies demonstrated that MRI is equivalent to histology in measurement of extramural depth, is also highly accurate in staging advanced rectal cancer, in the assessment of mesorectal fascia infiltration and to distinguish cT3 from cT4, in the measuring the distance from the anorectal ring.
  • In this time of changing therapeutic approaches, a common standard for large heterogeneous patient groups will likely be substituted by more individualised therapies.
  • It will depend from new evidence of more tailored diagnosis, surgery, radiotherapy and chemotherapy.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20496544.001).
  • [ISSN] 1128-3602
  • [Journal-full-title] European review for medical and pharmacological sciences
  • [ISO-abbreviation] Eur Rev Med Pharmacol Sci
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 31
  •  go-up   go-down


95. Lee MR, Hong CW, Yoon SN, Lim SB, Park KJ, Park JG: Risk factors for anastomotic leakage after resection for rectal cancer. Hepatogastroenterology; 2006 Sep-Oct;53(71):682-6
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Risk factors for anastomotic leakage after resection for rectal cancer.
  • BACKGROUND/AIMS: The aim of this study was to identify risk factors for anastomotic leakage in patients that have received a resection for rectal cancer.
  • METHODOLOGY: Between January 1996 and December 2002, 499 patients underwent rectal resection for rectal cancer performed by the same surgeon, and of these 25 patients developed anastomotic leakage.
  • CONCLUSIONS: We recommend proximal diversion in patients that have an anastomosis just above the anorectal ring (3.5-4.5cm from the anal verge), or received intraoperative transfusion (more than 0.2-1.4 packed red blood cells).

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17086868.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


96. Kao PS, Chang SC, Wang LW, Lee RC, Liang WY, Lin TC, Chen WS, Jiang JK, Yang SH, Wang HS, Lin JK: The impact of preoperative chemoradiotherapy on advanced low rectal cancer. J Surg Oncol; 2010 Dec 1;102(7):771-7
Hazardous Substances Data Bank. LEUCOVORIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The impact of preoperative chemoradiotherapy on advanced low rectal cancer.
  • BACKGROUND: Preoperative chemoradiotherapy (CCRT) followed by radical resection is an option for advanced low rectal cancer.
  • PATIENTS AND METHODS: One hundred thirty-six patients with rectal cancer (<10  cm from anal verge) were enrolled prospectively between July 2000 and December 2004.
  • RESULTS: There was no statistical difference in the preserved anorectal function between two groups after 5 years of follow-up (62.3% vs. 47.8%; P = 0.125).
  • CONCLUSIONS: In patients with advanced low rectal cancer, preoperative CCRT followed by radical surgery significantly improved overall survival and DFS compared with surgery alone.
  • [MeSH-major] Adenocarcinoma / therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Neoplasm Recurrence, Local / therapy. Rectal Neoplasms / therapy
  • [MeSH-minor] Administration, Oral. Combined Modality Therapy. Female. Humans. Leucovorin / administration & dosage. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Preoperative Care. Prognosis. Prospective Studies. Radiotherapy Dosage. Survival Rate. Tegafur / administration & dosage. Uracil / administration & dosage

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2010 Wiley-Liss, Inc.
  • (PMID = 20872811.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 1548R74NSZ / Tegafur; 56HH86ZVCT / Uracil; Q573I9DVLP / Leucovorin
  •  go-up   go-down


97. Urso E, Serpentini S, Pucciarelli S, De Salvo GL, Friso ML, Fabris G, Lonardi S, Ferraro B, Bruttocao A, Aschele C, Nitti D: Complications, functional outcome and quality of life after intensive preoperative chemoradiotherapy for rectal cancer. Eur J Surg Oncol; 2006 Dec;32(10):1201-8
Hazardous Substances Data Bank. FLUOROURACIL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Complications, functional outcome and quality of life after intensive preoperative chemoradiotherapy for rectal cancer.
  • AIMS: To investigate early and late complications in 44 patients with locally advanced mid-low rectal cancer enrolled in a phase I-II study, who had received an aggressive chemoradiation treatment (50.4Gy/28F; 5-FU continuous infusion and weekly Oxaliplatin) followed by total mesorectal excision and 5-FU based postoperative chemotherapy.
  • Anorectal function and QoL were also investigated in 22 patients who underwent surgery in the same surgical unit, using the fecal incontinence scoring system (FIS) and EORTC-QLQ-CR38 questionnaires, compiled before and after radiotherapy and at least 8 months after surgery.
  • CONCLUSION: Our findings seem to indicate that this aggressive 5-FU-Oxalipaltin-based treatment implies no impairment of QoL and anorectal function, even if a high rate of late major complications was observed.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • MedlinePlus Health Information. consumer health - After Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16872799.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin; U3P01618RT / Fluorouracil
  •  go-up   go-down


98. Chao M, Gibbs P, Tjandra J, Darben P, Lim-Joon D, Jones IT: Evaluation of the use of computed tomography versus conventional orthogonal X-ray simulation in the treatment of rectal cancer. Australas Radiol; 2005 Apr;49(2):122-6
MedlinePlus Health Information. consumer health - CT Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of the use of computed tomography versus conventional orthogonal X-ray simulation in the treatment of rectal cancer.
  • The aim of this study is to compare and contrast the treatment fields designed using CT versus conventional orthogonal X-ray simulation in the treatment of patients with rectal cancer given preoperative chemotherapy and radiotherapy.
  • The coverage of treatment fields, the volume of treatment fields, and the position of the anorectal junction in relation to the inferior border of the obturator foramen as the delineator of the pelvic floor were evaluated in each patient using CT and conventional orthogonal X-ray simulation.
  • In addition, the inferior border of the obturator foramen proved to be a poor delineator of the pelvic floor with the anorectal junction situated up to 2 cm superiorly in seven of nine patients.
  • In conclusion, CT simulation is superior to conventional orthogonal X-ray simulation when designing treatment fields for patients with rectal cancer.

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15845048.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


99. Gérard JP, Ortholan C, Benezery K, Ginot A, Hannoun-Levi JM, Chamorey E, Benchimol D, François E: Contact X-ray therapy for rectal cancer: experience in Centre Antoine-Lacassagne, Nice, 2002-2006. Int J Radiat Oncol Biol Phys; 2008 Nov 1;72(3):665-70
MedlinePlus Health Information. consumer health - Radiation Therapy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Contact X-ray therapy for rectal cancer: experience in Centre Antoine-Lacassagne, Nice, 2002-2006.
  • PURPOSE: To report the results of using contact X-ray (CXR), which has been used in the Centre-Lacassagne since 2002 for rectal cancer.
  • In the 7 patients who underwent TLE first, no local failure was observed, and their anorectal function was good.
  • CONCLUSION: These early results have confirmed that CXR combined with surgery (or alone with EBRT) can play a major role in the conservative and curative treatment of rectal cancer.
  • [MeSH-minor] Aged. Aged, 80 and over. Female. Follow-Up Studies. France. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Neoplasm Staging. Randomized Controlled Trials as Topic. Retrospective Studies. Time Factors

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18455327.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


100. Pietsch AP, Fietkau R, Klautke G, Foitzik T, Klar E: Effect of neoadjuvant chemoradiation on postoperative fecal continence and anal sphincter function in rectal cancer patients. Int J Colorectal Dis; 2007 Nov;22(11):1311-7
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of neoadjuvant chemoradiation on postoperative fecal continence and anal sphincter function in rectal cancer patients.
  • BACKGROUND AND AIMS: Neoadjuvant chemoradiation (nCRT) followed by curative surgery has gained acceptance as the therapy of choice in locally advanced rectal cancer.
  • This prospective study evaluates the effect of nCRT on postoperative anorectal function and continence.
  • All patients received a questionnaire to evaluate stool continence and anorectal function before as well as after surgery.
  • Anorectal function was further analyzed by perfusion manometry pre- and postoperatively.
  • Anorectal manometry revealed an impairment of anorectal function after low anterior resection regardless of the treatment regime.
  • CONCLUSION: nCRT does not impair anorectal function and fecal continence.

  • Genetic Alliance. consumer health - Anal Cancer.
  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17497160.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down






Advertisement