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1. Zhang L, Li X, Xu X, Zeng F: Correlation between antitumor activity, molecular weight, and conformation of lentinan. Carbohydr Res; 2005 Jun 13;340(8):1515-21
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  • The weight-average molecular weight (M(w)), radius of gyration (<S(2)>(z)(1/2)), and intrinsic viscosity ([eta]) of lentinan and its fractions in 0.9% NaCl aqueous solution and dimethyl sulfoxide (Me(2)SO) were determined by size-exclusion chromatography combined with multi-angle laser light scattering (SEC-LLS), LLS, and viscometry.
  • The [alpha](D) of lentinan in water-Me(2)SO mixtures indicated an order-disorder transition.
  • Assays in vivo and in vitro against the growth of Sarcoma 180 solid tumor as well as the colorimetric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method for lentinan showed that the triple-helix sample exhibited a relatively high inhibition ratio.
  • [MeSH-minor] Animals. Carbohydrate Conformation. Cell Line, Tumor. Cell Proliferation / drug effects. Chromatography, Gel. Male. Mice. Mice, Inbred BALB C. Molecular Weight. Sarcoma 180 / pathology. Xenograft Model Antitumor Assays

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  • (PMID = 15882854.001).
  • [ISSN] 0008-6215
  • [Journal-full-title] Carbohydrate research
  • [ISO-abbreviation] Carbohydr. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 37339-90-5 / Lentinan
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2. Marinović B, Mokos ZB, Basta-Juzbasić A, Jukić IL, Loncarić D, Hashimoto T, Pasić A: Atypical clinical appearance of pemphigus vulgaris on the face: case report. Acta Dermatovenerol Croat; 2005;13(4):233-6
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  • Pemphigus vulgaris is an organ-specific autoimmune mucocutaneous disorder.
  • A 78-year-old woman with yellowish crusted areas on her left preauricular region and close to the medial angle of her right eye is presented.
  • Before she presented to our Department, she was misdiagnosed as an actinic cheilitis and malignant skin tumor.

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  • (PMID = 16356397.001).
  • [ISSN] 1330-027X
  • [Journal-full-title] Acta dermatovenerologica Croatica : ADC
  • [ISO-abbreviation] Acta Dermatovenerol Croat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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3. Lee SH, Rhee BA, Choi SK, Koh JS, Lim YJ: Cerebellopontine angle tumors causing hemifacial spasm: types, incidence, and mechanism in nine reported cases and literature review. Acta Neurochir (Wien); 2010 Nov;152(11):1901-8
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  • [Title] Cerebellopontine angle tumors causing hemifacial spasm: types, incidence, and mechanism in nine reported cases and literature review.
  • OBJECTIVE: Although hemifacial spasm is usually caused by vascular compression around the root exit zone of the facial nerve, it is sometimes brought on by a cerebellopontine angle tumor.
  • We reviewed and analyzed data from past experience with hemifacial spasm induced by cerebellopontine angle tumors.
  • METHODS: Nine patients of a total 2,050, who had presented with hemifacial spasms associated with cerebellopontine angle tumors between 1986 and 2009, were reviewed.
  • With respect to the pathogenesis of hemifacial spasms, offending vessels were found in six patients, tumor encasement of the facial nerve in one patient, hypervascular tumor compression of the facial nerve without offending vessels in one patient, and a huge tumor compressing the brain stem and, thus, contralateral facial nerve compression in one patient.
  • Hemifacial spasm was resolved in seven patients, whereas in two patients with a vestibular schwannoma and an epidermoid tumor, it improved transiently and then recurred in a month.
  • CONCLUSIONS: Each type of tumor had different characteristics with respect to the induction of hemifacial spasm; therefore, it is suggested that neurosurgeons, who are planning surgeries both for the purposes of relieving hemifacial spasm and removal of cerebellopontine angle tumor, should thoroughly prepare appropriate approaches and specific dissecting strategies according to each causative lesion.

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  • (PMID = 20845049.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
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4. Brewis S, Baguley DM: Management of tinnitus induced by brainstem and cerebellar infarction associated with complications of cerebello-pontine angle surgery. J Laryngol Otol; 2007 Apr;121(4):393-4
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  • [Title] Management of tinnitus induced by brainstem and cerebellar infarction associated with complications of cerebello-pontine angle surgery.
  • Following surgery in the USA in 1992 to remove a large right cerebello-pontine angle tumour, a 39-year-old woman developed severe brainstem and cerebellar infarction.
  • [MeSH-major] Brain Stem Infarctions / complications. Cerebellar Neoplasms / complications. Cerebellopontine Angle. Cerebral Infarction / complications. Meningioma / complications. Tinnitus / etiology

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  • (PMID = 17403265.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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5. Zaouche S, Ionescu E, Dubreuil C, Ferber-Viart C: Pre- and intraoperative predictive factors of facial palsy in vestibular schwannoma surgery. Acta Otolaryngol; 2005 Apr;125(4):363-9
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  • Qualitative parameters: gender; side of the tumor; angle between the tumor and the internal auditory canal (VS/IAC angle) < or = or > 30 degrees; MRI aspect (n = 69); surgical approach; ease of the surgical procedure, the use or non-use of laser dissection; and the histological Antoni's type of the tumor.


6. Pan HC, Cheng FC, Chen CJ, Lai SZ, Liu MJ, Chang MH, Wang YC, Yang DY, Ho SP: Dietary supplement with fermented soybeans, natto, improved the neurobehavioral deficits after sciatic nerve injury in rats. Neurol Res; 2009 Jun;31(5):441-52
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  • Clearance of fibrin and associated inflammatory cytokines by tissue-type plasminogen activator (t-PA) is related to improved regeneration in neurological disorder.
  • Increased functional outcome such as sciatic nerve functional index, angle of ankle, compound muscle action potential and conduction latency were observed in natto-treated group.
  • Sciatic nerve crush injury induced elevation of tumor necrosis factor alpha (TNF-alpha) production and caused apoptosis.

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  • (PMID = 19309538.001).
  • [ISSN] 0161-6412
  • [Journal-full-title] Neurological research
  • [ISO-abbreviation] Neurol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cytokines; 9001-31-4 / Fibrin; 9001-32-5 / Fibrinogen
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7. Hong XY, Chou YC, Lazareff JA: Brain stem candidiasis mimicking cerebellopontine angle tumor. Surg Neurol; 2008 Jul;70(1):87-91
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  • [Title] Brain stem candidiasis mimicking cerebellopontine angle tumor.
  • The MRI of the patient showed an enhancing partially cystic and partially solid mass in the right CP angle cistern, interpreting as CP tumor.
  • CONCLUSIONS: Brainstem candidiasis in immunocompetent host can masquerade the CP angle tumor.
  • [MeSH-major] Candidiasis / diagnosis. Central Nervous System Fungal Infections / diagnosis. Cerebellar Neoplasms / diagnosis. Cerebellopontine Angle

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  • (PMID = 18313733.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Menetti F, Bartolomei I, Ambrosini-Spaltro A, Salvi F, Agati R, Leonardi M: Amyloidoma Involving the Orbit, Meckel's Cave and Infratemporal Fossa: 3T MRI Findings. Neuroradiol J; 2009 Mar 23;22(1):41-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The few literature reports of intracranial amyloidomas include lesions involving the pituitary gland, orbit, cerebral hemispheres, temporal bone, cerebellopontine angle and jugular foramen.
  • Thin contrast-enhanced MRI scans through the area of interest showed the mass to extend posterior to the gasserian ganglion, involving the cerebellopontine angle cistern, where the intracisternal parts of the III, V, and VI nerves bilaterally appeared enlarged and showed perineural enhancement.
  • The lesion closely mimicked a malignant tumor with perineural tumor infiltration, so we performed fine needle biopsy of the portion of the lesion near the right foramen ovale under fluoroscopic guidance.
  • Further clinical and blood examinations, serum chemistry, followed by biopsy of the periumbilical fat showed no signs of systemic amyloidosis or an underlying inflammatory or neoplastic disorder.

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  • (PMID = 24206952.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Anioł-Borkowska M, Namysłowski G, Lisowska G, Kwiek S, Hajduk A: [Evaluation of the cochlear efferent system in patients with cerebello-pontine angle tumor]. Pol Merkur Lekarski; 2005 Sep;19(111):283-5
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  • [Title] [Evaluation of the cochlear efferent system in patients with cerebello-pontine angle tumor].
  • The aim of the study was to estimate a cochlear efferent system in the group of patents with cerebello-pontine angle tumor (CPA).
  • The research was also conducted on the influence of tumor dimensions, age, sex, and the hearing level in tonal audiometry on the size of the efferent effect.
  • The research was carried out on a group of 14 patients with cerebello-pontine angle tumor and on an appropriate fourteen-person test group.
  • Having our results analyzed we were able to state that, compared with the test group, in the group of patients with CPA tumor significant reduce suppressions of otoacoustic emission response during CAS occurred both in an ear on the tumor side and in an ear on the healthy side.
  • However, the tumor dimensions, sex, and the hearing level in tonal audiometry seemed not to affect significantly the size of the efferent effect.

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  • (PMID = 16358843.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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10. James ML, Husain AM: Brainstem auditory evoked potential monitoring: when is change in wave V significant? Neurology; 2005 Nov 22;65(10):1551-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The probability of hearing loss during cerebellopontine angle (CPA) surgery can be reduced by using brainstem auditory evoked potential (BAEP) intraoperative monitoring (IOM).
  • When patients with CPA tumor were excluded, a significantly higher number of patients in Group 4 had hearing loss.
  • Analysis of the patients with CPA tumor showed no difference in the frequency of hearing loss in any of the groups; even a large number (50%) of Group 1 patients had hearing impairment.
  • For non-cerebellopontine angle tumor surgery, hearing loss occurs usually only with permanent loss of wave V; much smaller changes may be important in cerebellopontine angle tumor surgery.

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  • [CommentIn] Neurology. 2005 Nov 22;65(10):1522-3 [16301476.001]
  • (PMID = 16301480.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Mittelman D: Age-related distance esotropia. J AAPOS; 2006 Jun;10(3):212-3
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  • The distance deviation varied from 4 prism diopters (PD) ET (esotropia) to 20 PD ET, with a median angle of 9 PD ET.
  • None of these patients had an obvious underlying neurologic disorder, such as tumor or stroke.
  • The etiology of this disorder is unknown, but it is likely secondary to anatomical changes in the orbit and/or muscles associated with aging.

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  • [CommentIn] J AAPOS. 2007 Feb;11(1):69-70; author reply 70 [17307688.001]
  • (PMID = 16814172.001).
  • [ISSN] 1091-8531
  • [Journal-full-title] Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • [ISO-abbreviation] J AAPOS
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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12. Block F: [Disorders of the cerebellopontine angle]. Radiologe; 2006 Mar;46(3):185-6, 188-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Disorders of the cerebellopontine angle].
  • Disorders of the cerebellopontine angle may present by symptoms like vertigo, hearing problems, affection of the trigeminal or facial nerve.
  • Ipsilateral ataxia and contralateral hemiparesis develop in case of a rather large tumor in this region and display an involvement of the cerebellum and/or brainstem.
  • Thus, in case of a suspicion of a disorder of the cerebellopontine angle the relevant functions have to be tested clinically.
  • [MeSH-major] Cerebellar Diseases / diagnosis. Cerebellar Diseases / therapy. Cerebellopontine Angle / pathology. Hearing Disorders / diagnosis. Hearing Disorders / therapy. Vestibular Diseases / diagnosis. Vestibular Diseases / therapy

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  • (PMID = 16317531.001).
  • [ISSN] 0033-832X
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 6
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13. Roka YB, Bista P, Sharma GR, Sultania PK: Cerebellopontine epidermoid presenting with trigeminal neuralgia for 10 years: a case report. Cases J; 2009;2:9345
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The disorder causes extreme, sporadic, sudden burning or shock-like face pain that lasts from few seconds to minutes and can be physically and mentally incapacitating.
  • More than one nerve branch can be affected by the disorder.
  • Magnetic resonance imaging showed left cerebellopontine angle (CPA) mass suggestive of an epidermoid involving the Vth nerve and Gasserian ganglion and extending into the middle cranial fossa.
  • She underwent left suboccipital craniectomy and near total excision of the tumor with decompression of the V(th )nerve which was fully engulfed by the tumor.
  • TN caused by cerebellopontine angle epidermoids is uncommon and should be kept in view in all cases presenting with TN.

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  • (PMID = 20066061.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2804725
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14. Lisowska G, Namysłowski G, Misiołek M, Scierski W, Orecka B, Czecior E, Dziendziel A: [Efferent suppression test--sensitivity and specificity]. Otolaryngol Pol; 2008;62(6):747-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIAL AND METHODS: To evaluate the function of MOC system click evoked otoacoustic emissions (CEOAEs) with and without continuous contralateral broadband noise (BBN) stimulation were recorded in 14 patients with multiple sclerosis, 16 patients with unilateral cerebello-pontine angle tumor and control group matched for age and gender.
  • CONCLUSIONS: To conclude, assessment of efferent suppression may be a useful addition to the battery test employed in the investigation of multiple sclerosis and cerebello-pontine angle tumors.

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  • (PMID = 19205524.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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