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1. Gonçalves R, Martins MC, Oliveira MJ, Almeida-Porada G, Barbosa MA: Bioactivity of immobilized EGF on self-assembled monolayers: optimization of the immobilization process. J Biomed Mater Res A; 2010 Aug;94(2):576-85
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  • Surface characterization of EGF-SAMs was performed using radiolabeling, water contact angle measurements, X-ray photoelectron spectroscopy, and ELISA.
  • [MeSH-minor] Adsorption. Cell Line, Tumor. Enzyme-Linked Immunosorbent Assay. Gold / chemistry. Humans. Imidazoles / chemistry. Phosphorylation. Photoelectron Spectroscopy. Polyethylene Glycols / chemistry. Radioligand Assay. Receptor, Epidermal Growth Factor / metabolism. Sulfhydryl Compounds / chemistry. Surface Properties

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  • [Copyright] (c) 2010 Wiley Periodicals, Inc.
  • (PMID = 20198690.001).
  • [ISSN] 1552-4965
  • [Journal-full-title] Journal of biomedical materials research. Part A
  • [ISO-abbreviation] J Biomed Mater Res A
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / Imidazoles; 0 / Sulfhydryl Compounds; 30IQX730WE / Polyethylene Glycols; 62229-50-9 / Epidermal Growth Factor; 63A10X1FSP / N,N-carbonyldiimidazole; 7440-57-5 / Gold; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
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2. Hekmatyar SK, Wilson M, Jerome N, Salek RM, Griffin JL, Peet A, Kauppinen RA: ¹H nuclear magnetic resonance spectroscopy characterisation of metabolic phenotypes in the medulloblastoma of the SMO transgenic mice. Br J Cancer; 2010 Oct 12;103(8):1297-304
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  • METHODS: Transgenic mice over-expressing smoothened (SMO) receptor in granule cell precursors with high incidence of exophytic medulloblastomas were sequentially followed up by magnetic resonance imaging (MRI) and characterised for metabolite phenotypes by ¹H MR spectroscopy (MRS) in vivo and ex vivo using high-resolution magic angle spinning (HR-MAS) ¹H MRS.
  • RESULTS: Medulloblastomas in the SMO mice presented as T₂ hyperintense tumours in MRI.
  • These tumours showed low concentrations of N-acetyl aspartate and high concentrations of choline-containing metabolites (CCMs), glycine, and taurine relative to the cerebellar parenchyma in the wild-type (WT) C57BL/6 mice.
  • The MRS data from the medulloblastomas with defined molecular pathology is discussed in the light of metabolite profiles reported from human tumours.
  • [MeSH-major] Cerebellar Neoplasms / metabolism. Medulloblastoma / metabolism. Metabolome. Nuclear Magnetic Resonance, Biomolecular. Receptors, G-Protein-Coupled / genetics
  • [MeSH-minor] Animals. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Cerebellum / chemistry. Cerebellum / metabolism. Cerebellum / pathology. Choline / analysis. Choline / metabolism. Hydrogen / chemistry. Male. Mice. Mice, Inbred C57BL. Mice, Transgenic. Phenotype. Smoothened Receptor. Taurine / analysis. Taurine / metabolism. Tumor Burden / physiology

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  • (PMID = 20842126.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0601327; United Kingdom / Medical Research Council / /
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, G-Protein-Coupled; 0 / Smo protein, mouse; 0 / Smoothened Receptor; 1EQV5MLY3D / Taurine; 7YNJ3PO35Z / Hydrogen; N91BDP6H0X / Choline
  • [Other-IDs] NLM/ PMC2967063
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3. Jeblaoui Y, Ben Neji N, Haddad S, Zribi A, Néji R, Boussafa H, Sahtout S, Hchicha S: [Mandibular aneurysmal bone cyst mimicking a malignant tumor]. Rev Stomatol Chir Maxillofac; 2007 Jun;108(3):238-40
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  • [Title] [Mandibular aneurysmal bone cyst mimicking a malignant tumor].
  • [Transliterated title] Kyste osseux anévrismal mandibulaire mimant une tumeur maligne.
  • MRI suggested a diagnosis of a rhabdomyosarcoma but CT-scan evoked a benign lesion such as chondroblastoma or aneurismal bone cyst.
  • The biopsy specimen proved the diagnosis of aneurismal bone cyst and the patient was treated by surgical curettage.
  • The molar region, the angle, and the ascending ramus of the mandible are the predominantly affected sites.
  • [MeSH-major] Bone Cysts, Aneurysmal / diagnosis. Jaw Cysts / diagnosis. Mandibular Diseases / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Mandibular Neoplasms / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 17445848.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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4. Park BK, Kim CK: Prognostic factors influencing the development of an iatrogenic pneumothorax for computed tomography-guided radiofrequency ablation of upper renal tumor. Acta Radiol; 2008 Dec;49(10):1200-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic factors influencing the development of an iatrogenic pneumothorax for computed tomography-guided radiofrequency ablation of upper renal tumor.
  • BACKGROUND: Percutaneous radiofrequency (RF) ablation of upper renal tumors is considered a minimally invasive treatment, but this technique may cause pneumothorax.
  • PURPOSE: To assess retrospectively the prognostic factors influencing the development of iatrogenic pneumothorax for RF ablation of upper renal tumors.
  • MATERIAL AND METHODS: Computed tomography (CT)-guided RF ablation was performed in 24 patients (21 men, three women; age range 31-77 years, mean age 53.3 years) with 28 upper renal tumors.
  • Various factors for pneumothorax-complicated (PC) upper renal tumors and non-pneumothoracic (NP) upper renal tumors were compared during RF ablation to determine which of the factors were involved in the development of pneumothorax.
  • RESULTS: Among 28 upper renal tumors in 24 patients, a pneumothorax occurred accidentally in six patients with eight tumors and intentionally in two patients with two tumors.
  • PC upper renal tumors had shorter distance from the lung or from the costophrenic line to the tumor, a larger angle between the costophrenic line and the tumor, and a higher incidence of intervening lung tissue than NP upper renal tumors (P<0.01).
  • CONCLUSION: The presence of intervening lung tissue and the close proximity between an upper renal tumor and the lung are high risk factors for developing an iatrogenic pneumothorax.
  • [MeSH-major] Catheter Ablation / methods. Iatrogenic Disease. Kidney Neoplasms / surgery. Pneumothorax / diagnosis. Pneumothorax / etiology. Tomography, X-Ray Computed / methods

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  • (PMID = 19031183.001).
  • [ISSN] 1600-0455
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Contrast Media
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5. Gokcan MK, Batikhan H, Calguner M, Tataragasi AI: Unilateral hearing loss as a presenting manifestation of granulocytic sarcoma (chloroma). Otol Neurotol; 2006 Jan;27(1):106-9
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  • OBJECTIVE: To present a case of acute granulocytic sarcoma of the cerebellopontine angle whose presenting symptom was sudden onset unilateral sensorineural hearing loss.
  • Magnetic resonance imaging of the cranium revealed findings consistent with granulocytic sarcoma at the cerebellopontine angle, infiltrating the internal acoustic canal.
  • As increased intracranial pressure symptoms developed subsequently, subtotal tumor resection was performed.
  • The patient presented in this report is the first reported case with a granulocytic sarcoma of the cerebellopontine angle who presented with acute sensorineural hearing loss.
  • [MeSH-major] Cerebellar Neoplasms / complications. Cerebellar Neoplasms / diagnosis. Cerebellopontine Angle. Hearing Loss, Sudden / etiology. Sarcoma, Myeloid / complications. Sarcoma, Myeloid / diagnosis

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  • (PMID = 16371856.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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6. Tsujikawa T, Saitoh Y, Andoh A, Imaeda H, Hata K, Minematsu H, Senoh K, Hayafuji K, Ogawa A, Nakahara T, Sasaki M, Fujiyama Y: Novel single-balloon enteroscopy for diagnosis and treatment of the small intestine: preliminary experiences. Endoscopy; 2008 Jan;40(1):11-5
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  • [Title] Novel single-balloon enteroscopy for diagnosis and treatment of the small intestine: preliminary experiences.
  • Instead of a balloon attached to the distal scope end, the distal scope end was hook-shaped, and manipulating the up-angle or down-angle of the scope end enabled exploration of the small intestine.
  • The indications for the examination were suspected mid-gastrointestinal bleeding (n = 12), Crohn's disease (n = 17), abdominal pain (n = 8), and abdominal tumor (n = 4).
  • [MeSH-major] Endoscopy, Gastrointestinal / methods. Intestinal Diseases / diagnosis. Intestinal Diseases / therapy. Intestine, Small
  • [MeSH-minor] Abdominal Neoplasms / diagnosis. Abdominal Neoplasms / therapy. Abdominal Pain / diagnosis. Abdominal Pain / therapy. Adult. Aged. Aged, 80 and over. Cohort Studies. Crohn Disease / diagnosis. Crohn Disease / therapy. Equipment Design. Equipment Safety. Female. Gastrointestinal Hemorrhage / diagnosis. Gastrointestinal Hemorrhage / therapy. Humans. Japan. Male. Middle Aged. Reproducibility of Results. Risk Assessment. Sensitivity and Specificity. Treatment Outcome

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  • [CommentIn] Endoscopy. 2008 Jun;40(6):537; author reply 539 [18543140.001]
  • [CommentIn] Endoscopy. 2008 Nov;40(11):961-2; author reply 962 [19009491.001]
  • [CommentIn] Endoscopy. 2008 Jun;40(6):538; author reply 539 [18543141.001]
  • (PMID = 18058613.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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7. Chen JC, Tseng SH, Chen Y, Tzeng JE, Lin SM: Cervical dumbbell meningioma and thoracic dumbbell schwannoma in a patient with neurofibromatosis. Clin Neurol Neurosurg; 2005 Apr;107(3):253-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Magnetic resonance imaging (MRI) revealed bilateral cerebellopontine angle tumors, a C1-2 dumbbell tumor, and a T5-6 dumbbell tumor.
  • The cervical spine and thoracic spine tumors were removed via one-staged combined posterior (laminectomy) and antero-lateral (transforaminal or thoracoscopic) approaches during two operations performed 1 month apart.
  • Six months after the second surgery, radiosurgery was performed for the bilateral acoustic tumors, because of enlarged tumor size on follow-up MRI.
  • A literature review of the dumbbell tumors was done, and their treatment strategies were discussed.

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  • (PMID = 15823685.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 19
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8. Anand VK, Schwartz TH, Hiltzik DH, Kacker A: Endoscopic transphenoidal pituitary surgery with real-time intraoperative magnetic resonance imaging. Am J Rhinol; 2006 Jul-Aug;20(4):401-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient demographics, tumor measurements, and postoperative symptoms and complications were assessed.
  • The effect of the magnetic field on the video screen, the image quality of the IMRI images, and IMRI detection of residual tumor were evaluated also.
  • RESULTS: IMRI images were obtained in all cases and were of sufficiently high quality to indicate adequate decompression of the optic chiasm and the removal of all suprasellar tumor.
  • However, there was significant distortion of the video monitor regardless of the viewing angle.
  • Residual tumor was found with IMRI and resected endoscopically in three cases.
  • In two other cases, suspected residual tumor on IMRI was examined endoscopically and found to be a normal postoperative change.
  • In two cases no tumor was seen on the IMRI.

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  • (PMID = 16955768.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Zhang F, Xie ZJ, Ge WL, Li SL, Li YN: Tensile force produced by a lipoma in the masseteric space possibly causing hyperostosis of the angle of the mandible. Med Sci Monit; 2009 Sep;15(9):CS148-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tensile force produced by a lipoma in the masseteric space possibly causing hyperostosis of the angle of the mandible.
  • BACKGROUND: A lipoma is a benign tumor which may occur in the adipose tissue of any part of the body.
  • The tumor is most commonly found on the trunk and extremities.
  • Although it is the most common tumor of mesenchymal origin in the head and neck, its incidence is relatively rare.
  • The mass was revealed to be a classical lipoma in the masseteric space, possibly causing hyperostosis of the angle of the mandible.
  • After removal of the mass and a spherical protuberance in the angle of the mandible, the boy recovered and no recurrence was noted after one-year follow-up.
  • In this case, the hypothesis was posed that the tensile force produced by the lipoma in the masseteric space possibly caused hyperostosis of the angle of the mandible.

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  • (PMID = 19721405.001).
  • [ISSN] 1643-3750
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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10. Zhu W, Li Y, Liu L, Chen Y, Wang C, Xi F: Supramolecular hydrogels from cisplatin-loaded block copolymer nanoparticles and α-cyclodextrins with a stepwise delivery property. Biomacromolecules; 2010 Nov 8;11(11):3086-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Structures and properties of the supramolecular hydrogels containing cisplatin were studied by wide-angle X-ray diffraction (XRD) and rheology measurements, respectively.
  • [MeSH-minor] Cell Line, Tumor. Cell Proliferation / drug effects. Cell Survival / drug effects. Dose-Response Relationship, Drug. Drug Screening Assays, Antitumor. Humans. Macromolecular Substances / chemical synthesis. Macromolecular Substances / chemistry. Macromolecular Substances / pharmacology. Micelles. Particle Size. Structure-Activity Relationship. Surface Properties

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  • (PMID = 20958000.001).
  • [ISSN] 1526-4602
  • [Journal-full-title] Biomacromolecules
  • [ISO-abbreviation] Biomacromolecules
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acrylic Resins; 0 / Antineoplastic Agents; 0 / Hydrogels; 0 / Macromolecular Substances; 0 / Micelles; 0 / alpha-Cyclodextrins; 30IQX730WE / Polyethylene Glycols; 9003-01-4 / carbopol 940; Q20Q21Q62J / Cisplatin
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11. Ristori S, Di Cola E, Lunghi C, Richichi B, Nativi C: Structural study of liposomes loaded with a GM3 lactone analogue for the targeting of tumor epitopes. Biochim Biophys Acta; 2009 Dec;1788(12):2518-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Structural study of liposomes loaded with a GM3 lactone analogue for the targeting of tumor epitopes.
  • Therapeutic vaccination with tumor antigens is a new approach in cancer treatment, which aims at inducing immune response while avoiding the side effects generally associated to many conventional therapies.
  • SNeuAC-C14 is a potential vaccine for the targeting of saccharide-based tumor epitopes.
  • Different liposome formulations were designed to act as carriers and to generate recognition by tumor epitopes.
  • The structural study of pure and loaded liposomes was carried out by synchrotron Small Angle X-ray Scattering and was complemented by Dynamic Light Scattering and Zeta potential measurements.
  • The obtained results allow these systems to be considered as candidates to promote immunoresponse in tumor cells.

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  • (PMID = 19837046.001).
  • [ISSN] 0006-3002
  • [Journal-full-title] Biochimica et biophysica acta
  • [ISO-abbreviation] Biochim. Biophys. Acta
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cancer Vaccines; 0 / Epitopes; 0 / G(M3) Ganglioside; 0 / Lipid Bilayers; 0 / Liposomes; 99477-47-1 / ganglioside GM3 lactone
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12. Benatiya Andaloussi I, Touiza E, Bhallil S, Oudidi A, Bouayed MA, Daoudi K, El Alami MN, Tahri H: Orbital osteoma: three case reports. Bull Soc Belge Ophtalmol; 2006;(300):73-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Osteoma is the most frequent benign tumor of paranasal sinuses.
  • The management consisted in a surgical excision of the whole tumor by external approach, associated with a dacryocystorhinostomy.
  • 2nd observation: Miss K.A. is a 16 years-old caucasian female who came to consultation for a swelling of the medial angle of the left eye.
  • The tumor was removed through an external ethmoidectomy.
  • The computed tomography is of a great contribution, not only for diagnosis but also for the choice of the surgical approach.
  • [MeSH-major] Orbital Neoplasms / diagnosis. Osteoma / diagnosis

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  • (PMID = 16903514.001).
  • [ISSN] 0081-0746
  • [Journal-full-title] Bulletin de la Société belge d'ophtalmologie
  • [ISO-abbreviation] Bull Soc Belge Ophtalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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13. Wadasadawala T, Trivedi S, Gupta T, Epari S, Jalali R: The diagnostic dilemma of primary central nervous system melanoma. J Clin Neurosci; 2010 Aug;17(8):1014-1017
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  • The CNS can be affected by a spectrum of melanocytic lesions ranging from diffuse neurocutaneous melanosis, to a focal and benign neoplasm (melanocytoma), and to an overtly malignant tumor (melanoma).
  • Primary CNS melanoma cannot be reliably distinguished from metastatic melanoma on neuroimaging and histopathological characteristics alone: its diagnosis is established only after exclusion of secondary metastatic disease from a cutaneous, mucosal or retinal primary.
  • [MeSH-major] Brain Neoplasms / pathology. Cerebellopontine Angle / pathology. Melanoma / pathology. Parietal Lobe / pathology

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  • (PMID = 20627582.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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14. Kambe A, Kamitani H, Watanabe T, Oka A, Inagaki H, Ishii T, Ueki K: A non-NF2 case of schwannomas of vestibular and trigeminal nerves with different genetic alterations of NF2 gene: case report. Surg Neurol; 2005 Jan;63(1):62-4; discussion 64-5
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  • BACKGROUND: We report a patient with 2 separate schwannomas, a vestibular schwannoma and a trigeminal schwannoma, that were attached to each other and appeared to be a single tumor on imaging studies.
  • Magnetic resonance imaging showed a snowman-like tumor in the left cerebellopontine angle.
  • Surgical exposure revealed that the tumor consisted of 2 "kissing" schwannomas, a trigeminal and vestibular schwannoma.
  • However, loss of heterozygosity at chromosome 22q (D22S282 and D22S929) was detected in both tumors, losing the same allele.

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  • (PMID = 15639530.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Kiran NA, Suri A, Kasliwal MK, Garg A, Ahmad FU, Mahapatra AK: Gross total excision of pediatric giant cystic craniopharyngioma with huge retroclival extension to the level of foramen magnum by anterior trans petrous approach: report of two cases and review of literature. Childs Nerv Syst; 2008 Mar;24(3):385-91
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  • [Title] Gross total excision of pediatric giant cystic craniopharyngioma with huge retroclival extension to the level of foramen magnum by anterior trans petrous approach: report of two cases and review of literature.
  • The objective of this paper is to report that such rare cases of giant cystic predominantly retrochiasmatic retroclival craniopharyngiomas can be completely excised by an anterior transpetrous approach in a single stage.
  • Preoperative computed tomography (CT) and magnetic resonance imaging (MRI) in both these patients revealed a giant sellar suprasellar cystic lesion with areas of calcification and the lesion was predominantly retrochiasmatic with a huge retroclival posterior fossa extension down to the level of the C1 vertebra and laterally to the cerebellopontine angle.
  • Gross total excision of both suprasellar and posterior fossa extensions could be done in both the patients through an anterior transpetrous transtentorial approach (Kawase's approach).
  • RESULTS: Postoperative imaging (MRI/CT) revealed no obvious evidence of residual tumor.

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  • (PMID = 18034348.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 15
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16. Savoldelli C, Righini C, Reyt E, Lebeau J, Bettega G: [Lateral transmandibular route for deep-lobe parotid tumor excision]. Rev Stomatol Chir Maxillofac; 2009 Jun;110(3):150-4
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  • [Title] [Lateral transmandibular route for deep-lobe parotid tumor excision].
  • [Transliterated title] Abord transmandibulaire latéral pour l'exérèse des tumeurs du lobe profond de la parotide.
  • The parapharyngeal space may be a site for tumors, especially for those developed in the deep parotid lobe.
  • The surgical route to parapharyngeal space tumors is a challenge because of neighbor anatomic structures and the specific risk of mandibular nerve damage.
  • The aim of this study was to describe an original lateral transmandibular route, setting aside the mandible angle and preserving the mandibular nerve.
  • [MeSH-minor] Adenoma, Pleomorphic / surgery. Adipose Tissue / pathology. Bone Plates. Connective Tissue / pathology. Fascia / pathology. Humans. Intraoperative Complications / prevention & control. Mandibular Condyle / surgery. Mandibular Nerve / pathology. Masseter Muscle / surgery. Neck Muscles / pathology. Neck Muscles / surgery. Neoplasm Invasiveness. Pharyngeal Muscles / pathology. Pharynx / surgery. Pterygoid Muscles / pathology. Reconstructive Surgical Procedures / instrumentation. Reconstructive Surgical Procedures / methods. Temporal Muscle / surgery. Trigeminal Nerve Injuries

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  • (PMID = 19423144.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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17. Lin HY, Yeh CT: Controlled release of pentoxifylline from porous chitosan-pectin scaffolds. Drug Deliv; 2010 Jul;17(5):313-21
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  • As the amounts of pectin added to chitosan increased (0%, 0.5%, 1%, and 2%) the scaffolds became more wettable (contact angle decreased from 81 degrees to 76 degrees ), less swellable (swelling ratio decreased from 35% to 30%), and less capable of releasing pentoxifylline (PTX) (release efficacies decreased from 93% to 83%).
  • [MeSH-minor] Animals. Cross-Linking Reagents / chemistry. Delayed-Action Preparations. Drug Carriers / chemistry. Elastic Modulus. Interleukin-6 / antagonists & inhibitors. Macrophages / drug effects. Macrophages / metabolism. Mice. Porosity. Spectroscopy, Fourier Transform Infrared. Tumor Necrosis Factor-alpha / antagonists & inhibitors

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  • (PMID = 20370329.001).
  • [ISSN] 1521-0464
  • [Journal-full-title] Drug delivery
  • [ISO-abbreviation] Drug Deliv
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cross-Linking Reagents; 0 / Delayed-Action Preparations; 0 / Drug Carriers; 0 / Interleukin-6; 0 / Pectins; 0 / Phosphodiesterase Inhibitors; 0 / Tumor Necrosis Factor-alpha; 9000-69-5 / pectin; 9012-76-4 / Chitosan; SD6QCT3TSU / Pentoxifylline
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18. Wang X, Zhang L: Physicochemical properties and antitumor activities for sulfated derivatives of lentinan. Carbohydr Res; 2009 Nov 2;344(16):2209-16
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  • The (13)C NMR spectra of the sulfated beta-glucans indicated that the C-6 position was preferentially substituted by the sulfate groups.
  • The values of the weight-average molecular weight (M(w)), radius of gyration (s(2)(z)(1/2)), and intrinsic viscosity ([eta]) of the sulfated lentinan fractions were determined by size-exclusion chromatography with multi-angle laser light scattering (SEC-MALLS) and viscometry in 0.15 M aq NaCl at 25 degrees C, respectively.
  • [MeSH-minor] Animals. Carbohydrate Conformation. Cell Line, Tumor. Cell Proliferation / drug effects. Molecular Weight. Solubility. Ultrasonics. Water / chemistry

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  • (PMID = 19733344.001).
  • [ISSN] 1873-426X
  • [Journal-full-title] Carbohydrate research
  • [ISO-abbreviation] Carbohydr. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Sulfonic Acids; 059QF0KO0R / Water; 2O9AXL1TJ4 / chlorosulfonic acid; 37339-90-5 / Lentinan
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19. Olivero G, Maiolo D, Leali D, Federici S, Depero LE, Presta M, Mitola S, Bergese P: Nanoliter contact angle probes tumor angiogenic ligand-receptor protein interactions. Biosens Bioelectron; 2010 Dec 15;26(4):1571-5
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  • [Title] Nanoliter contact angle probes tumor angiogenic ligand-receptor protein interactions.
  • Sessile contact angle (CA) experiments can be readily used to track this thermodynamic parameter, prompting this well-known technique to be reinvented as an alternative, easy-access and label-free way to probe and study molecular recognition events.
  • Here we deploy this technique, renamed for this application CONAMORE (CONtact Angle MOlecular REcognition), to study the interaction of the tumor-derived pro-angiogenic vascular endothelial growth factor-A (VEGF-A) with the extracellular domain of its receptor VEGFR2.

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  • [Copyright] Copyright © 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20810271.001).
  • [ISSN] 1873-4235
  • [Journal-full-title] Biosensors & bioelectronics
  • [ISO-abbreviation] Biosens Bioelectron
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenic Proteins; 0 / Endothelial Growth Factors; 0 / Immobilized Proteins; 0 / Ligands; 0 / Peptides, Cyclic; 0 / Recombinant Fusion Proteins; 0 / Recombinant Proteins; 0 / VEGFA protein, human; 0 / VEGFR-2-Fc chimeric protein; 0 / Vascular Endothelial Growth Factor A; 0 / cyclo-VEGI
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20. Zhang P, Happersett L, Hunt M, Jackson A, Zelefsky M, Mageras G: Volumetric modulated arc therapy: planning and evaluation for prostate cancer cases. Int J Radiat Oncol Biol Phys; 2010 Apr;76(5):1456-62
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  • Multileaf collimator apertures and dose rates were optimized with respect to gantry angle subject to dose-volume-based objectives.
  • Plan evaluation statistics included the percentage of planning target volume (PTV) receiving 95% of prescribed dose (V95), dose to 95% of PTV (D95), mean PTV dose, tumor control probability, and dosimetric endpoints of normal organs, whereas monitor unit (MU) and delivery time were used to assess delivery efficiency.
  • RESULTS: Patient-averaged PTV V95, D95, mean dose, and tumor control probability in VMAT plans were 96%, 82.6 Gy, 88.5 Gy, and 0.920, respectively, vs. 97%, 84.0 Gy, 88.9 Gy, and 0.929 in IMRT plans.


21. Fukuoka S, Howe J, Andrä J, Gutsmann T, Rössle M, Brandenburg K: Physico-chemical and biophysical study of the interaction of hexa- and heptaacyl lipid A from Erwinia carotovora with magainin 2-derived antimicrobial peptides. Biochim Biophys Acta; 2008 Oct;1778(10):2051-7
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  • The electrophoretic mobility of lipid A aggregates under the influence of the peptides was studied to determine the Zeta potential, and small-angle X-ray scattering was applied for the elucidation of the types of aggregate structures in the absence and presence of the peptides.
  • The lipid A-induced cytokine production in human mononuclear cells shows that the ability of the two peptides to inhibit a tumor necrosis factor-alpha production correlates with characteristic changes of the biophysical parameters.
  • [MeSH-minor] Animals. Humans. Leukocytes, Mononuclear / immunology. Magainins. Spectroscopy, Fourier Transform Infrared. Tumor Necrosis Factor-alpha / immunology

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  • (PMID = 18440300.001).
  • [ISSN] 0006-3002
  • [Journal-full-title] Biochimica et biophysica acta
  • [ISO-abbreviation] Biochim. Biophys. Acta
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Infective Agents; 0 / Antimicrobial Cationic Peptides; 0 / Lipid A; 0 / Magainins; 0 / Tumor Necrosis Factor-alpha; 0 / Xenopus Proteins; 108433-95-0 / magainin 2 peptide, Xenopus
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22. Shirosaki Y, Tsuru K, Hayakawa S, Osaka A, Lopes MA, Santos JD, Costa MA, Fernandes MH: Physical, chemical and in vitro biological profile of chitosan hybrid membrane as a function of organosiloxane concentration. Acta Biomater; 2009 Jan;5(1):346-55
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  • The swelling ability, contact angle and cytocompatibility of the hybrids were investigated as a function of the GPTMS concentration.
  • [MeSH-minor] Bone Marrow Cells / cytology. Bone Marrow Cells / metabolism. Cell Line, Tumor. Cell Proliferation. Cell Survival. Cross-Linking Reagents / chemistry. Humans. Magnetic Resonance Spectroscopy. Microscopy, Electron, Scanning. Osteoblasts / metabolism. Spectrophotometry, Ultraviolet. Spectroscopy, Fourier Transform Infrared. Tissue Engineering / methods

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  • (PMID = 18722166.001).
  • [ISSN] 1878-7568
  • [Journal-full-title] Acta biomaterialia
  • [ISO-abbreviation] Acta Biomater
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cross-Linking Reagents; 0 / Silanes; 0 / Siloxanes; 2530-83-8 / gamma-glycidoxypropyltrimethoxysilane; 9012-76-4 / Chitosan
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23. Syal R, Reddy S J, Kumar R, Tyagi I, Abrar AA, Krishnani N, Mishra AM, Gupta RK: Unusual clinical and MRI features of a cerebellopontine angle medulloepithelioma. Case report and review of literature. Pediatr Neurosurg; 2006;42(5):299-303
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  • [Title] Unusual clinical and MRI features of a cerebellopontine angle medulloepithelioma. Case report and review of literature.
  • We describe for the first time an unusual location and clinical presentation of medulloepithelioma, a rare embryonal tumor.
  • On imaging, the lesion appeared to be extra axial and was located in the right cerebello-pontine (CP) angle, extending into middle fossa along the trigeminal ganglion and in front of the brain stem into the opposite CP angle.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Cerebellopontine Angle / pathology. Magnetic Resonance Imaging. Neuroectodermal Tumors, Primitive / diagnosis
  • [MeSH-minor] Brain Chemistry. Child, Preschool. Choline / analysis. Creatine / analysis. Glycine / analysis. Hearing Loss, Bilateral / etiology. Humans. Lactic Acid / analysis. Magnetic Resonance Spectroscopy. Neoplasm, Residual / diagnosis

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  • [Copyright] Copyright 2006 S. Karger AG, Basel.
  • (PMID = 16902342.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 33X04XA5AT / Lactic Acid; MU72812GK0 / Creatine; N91BDP6H0X / Choline; TE7660XO1C / Glycine
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24. Niedziela T, Letowska I, Lukasiewicz J, Kaszowska M, Czarnecka A, Kenne L, Lugowski C: Epitope of the vaccine-type Bordetella pertussis strain 186 lipooligosaccharide and antiendotoxin activity of antibodies directed against the terminal pentasaccharide-tetanus toxoid conjugate. Infect Immun; 2005 Nov;73(11):7381-9
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  • Lipooligosaccharides (LOS) isolated from Bordetella pertussis strains 186 and 606 were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and high-resolution magic angle spinning nuclear magnetic resonance (NMR).
  • The antipentasaccharide antibodies induced by the conjugate inhibited the secretion of tumor necrosis factor alpha, interleukin-6, and NO by LOS-stimulated J774A.1 cells.
  • [MeSH-minor] Animals. Carbohydrate Conformation. Cell Line. Endotoxins / immunology. Epitope Mapping. Gene Expression Regulation. Immune Sera / immunology. Immunoconjugates / chemistry. Immunoconjugates / immunology. Interleukin-6 / secretion. Macrophages / immunology. Nitric Oxide / metabolism. Nitric Oxide / secretion. Rabbits. Tumor Necrosis Factor-alpha / secretion

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  • (PMID = 16239537.001).
  • [ISSN] 0019-9567
  • [Journal-full-title] Infection and immunity
  • [ISO-abbreviation] Infect. Immun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Bacterial; 0 / Endotoxins; 0 / Immune Sera; 0 / Immunoconjugates; 0 / Immunodominant Epitopes; 0 / Interleukin-6; 0 / Lipopolysaccharides; 0 / Pertussis Vaccine; 0 / Tetanus Toxoid; 0 / Tumor Necrosis Factor-alpha; 0 / lipid-linked oligosaccharides; 31C4KY9ESH / Nitric Oxide
  • [Other-IDs] NLM/ PMC1273879
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25. Lindegaard J, Isager P, Prause JU, Heegaard S: Optic nerve invasion of uveal melanoma. APMIS; 2007 Jan;115(1):1-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Prelaminar/laminar optic nerve invasion was in multivariate analysis associated with focal retinal invasion, neovascularization of the chamber angle, and scleral invasion.
  • 1) by tumor extension from the neuroretina through the lamina cribrosa;.
  • 3) by direct invasion through the border tissue of Elschnig; and 4) in one case a tumor spread along the inner limiting membrane to the optic nerve through the lamina cribrosa.
  • The majority of melanomas invading the optic nerve are large juxtapapillary tumors invading the optic nerve because of simple proximity to the nerve.
  • A neurotropic subtype invades the optic nerve and retina in a diffuse fashion unrelated to tumor size or location.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Eye Enucleation. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness

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  • (PMID = 17223846.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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26. Limb CJ, Long DM, Niparko JK: Acoustic neuromas after failed radiation therapy: challenges of surgical salvage. Laryngoscope; 2005 Jan;115(1):93-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nine nonirradiated case-control subjects matched for age, sex, tumor size, and surgical approach were identified for purposes of general comparison.
  • Excessive scarring hindered identification of the facial nerve and added uncertainty as to the completeness of tumor removal.
  • Decompression of the internal auditory canal (IAC) dura and resection of neoplasm in the IAC before cerebellopontine angle dissection was required for facial nerve identification.
  • Poorer outcomes of postoperative cranial nerve status were caused primarily by anatomic changes at the nerve/tumor interface.

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  • (PMID = 15630374.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Li H, Standish BA, Mariampillai A, Munce NR, Mao Y, Chiu S, Marcon NE, Wilson BC, Vitkin A, Yang VX: Feasibility of interstitial Doppler optical coherence tomography for in vivo detection of microvascular changes during photodynamic therapy. Lasers Surg Med; 2006 Sep;38(8):754-61
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  • Using Dunning prostate cancer in a rat xenograft model, this study evaluated the feasibility of IS-DOCT monitoring of microvascular changes deep within a tumor caused by photodynamic therapy (PDT).
  • The lens of the probe consisted of a gradient-index fiber, fusion spliced to an angle-polished coreless tip to allow side-view scanning.
  • The resultant IS-DOCT system was used to monitor microvascular changes deep within the tumor mass in response to PDT in the rat xenograft model of Dunning prostate cancer.
  • This capability may play an important role in elucidating the mechanisms of PDT in tumors, pre-treatment planning, feedback control for treatment optimization, determining treatment endpoints and post-treatment assessments.
  • [MeSH-minor] Animals. Cell Line, Tumor. Dihematoporphyrin Ether / pharmacology. Equipment Design. Feasibility Studies. Male. Microcirculation / drug effects. Neoplasm Transplantation. Photosensitizing Agents / pharmacology. Rats. Ultrasonography, Doppler, Color

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  • [Copyright] (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16927368.001).
  • [ISSN] 0196-8092
  • [Journal-full-title] Lasers in surgery and medicine
  • [ISO-abbreviation] Lasers Surg Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 97067-70-4 / Dihematoporphyrin Ether
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28. Samii A, Lenarz M, Majdani O, Lim HH, Samii M, Lenarz T: Auditory midbrain implant: a combined approach for vestibular schwannoma surgery and device implantation. Otol Neurotol; 2007 Jan;28(1):31-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: The lateral suboccipital craniotomy enabled sufficient exposure of the cerebellopontine angle and internal auditory canal for tumor removal.

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  • (PMID = 17195743.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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29. Zhang QJ, Zhong J, Fang SH, Wang YQ: Branchiostoma japonicum and B. belcheri are distinct lancelets (Cephalochordata) in Xiamen waters in China. Zoolog Sci; 2006 Jun;23(6):573-9
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  • 3) the caudal fin of B. belcheri is narrower than that of B. japonicum, and the angle between the dorsal and super-caudal fins, and between preanal and sub-caudal fins, is obtuse in B. belcheri but acute in B. japonicum.

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  • (PMID = 16849846.001).
  • [ISSN] 0289-0003
  • [Journal-full-title] Zoological science
  • [ISO-abbreviation] Zool. Sci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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30. de Souza Filho JP, Martins MC, Torres VL, Dias AB, Lowen MS, Pires LA, Erwenne CM: [Histopathologic findings in retinoblastoma]. Arq Bras Oftalmol; 2005 May-Jun;68(3):327-31
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  • The histopathological review evaluated the presence of iris and/or angle neovascularization, tumor differentiation and optic nerve and choroidal invasion according to Khelfaoui's classification.
  • All tumors were histologically characterized by a proliferation of small cells with high nuclear-to-cytoplasmic ratios and 20 (71.4%) of them were well differentiated.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Combined Modality Therapy. Eye Enucleation. Female. Humans. Infant. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neovascularization, Pathologic / pathology. Prognosis

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  • (PMID = 16059563.001).
  • [ISSN] 0004-2749
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
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31. Schlieter M, Zoubaa S, Kress B, Unterberg A, Jacobi C, Hähnel S: Hemorrhagic acoustic schwannoma: radiological and histopathological findings. J Neuroradiol; 2005 Jun;32(3):210-2
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  • CT and MRI revealed a cerebellopontine angle tumor 15mm in diameter and acute intratumoral hematoma.

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  • (PMID = 16134303.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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32. Bennett M, Haynes DS: Surgical approaches and complications in the removal of vestibular schwannomas. Otolaryngol Clin North Am; 2007 Jun;40(3):589-609, ix-x
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Vestibular schwannomas are benign tumors that usually originate from the balance portion of cranial nerve VIII.
  • Although the ultimate goal in treatment of vestibular schwannomas is preservation of life, the best option for each patient depends on symptoms, tumor size, tumor location, and the patient's general health and age.
  • Surgical exposure of the cerebellopontine angle for removal of vestibular schwannomas can be performed safely via a translabyrinthine, retrosigmoid, and middle fossa approach.
  • The goal of surgery is complete eradication of tumor with preservation of hearing and facial nerve function when possible.
  • [MeSH-minor] Cerebrospinal Fluid Otorrhea / epidemiology. Cerebrospinal Fluid Otorrhea / etiology. Facial Nerve Diseases / epidemiology. Facial Nerve Diseases / etiology. Headache / epidemiology. Headache / etiology. Humans. Meningitis / epidemiology. Meningitis / etiology. Neoplasm Recurrence, Local. Postoperative Complications. Postural Balance / physiology. Tinnitus / epidemiology. Tinnitus / etiology

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  • (PMID = 17544697.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
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33. Silva RE, Arruda JT, Rodrigues FW, Moura KK: Primary open angle glaucoma was not found to be associated with p53 codon 72 polymorphism in a Brazilian cohort. Genet Mol Res; 2009;8(1):268-72
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  • [Title] Primary open angle glaucoma was not found to be associated with p53 codon 72 polymorphism in a Brazilian cohort.
  • Primary open angle glaucoma (POAG) is the most common type of glaucoma.
  • We examined the distribution of this polymorphism in 104 unrelated POAG patients and in 58 normal healthy individuals without history of POAG at the Pronto Clínica de Olhos in Goiânia, Brazil.
  • [MeSH-major] Codon / genetics. Glaucoma, Open-Angle / genetics. Polymorphism, Genetic. Tumor Suppressor Protein p53 / genetics

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  • (PMID = 19291875.001).
  • [ISSN] 1676-5680
  • [Journal-full-title] Genetics and molecular research : GMR
  • [ISO-abbreviation] Genet. Mol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Codon; 0 / Tumor Suppressor Protein p53
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34. Opstad KS, Bell BA, Griffiths JR, Howe FA: An assessment of the effects of sample ischaemia and spinning time on the metabolic profile of brain tumour biopsy specimens as determined by high-resolution magic angle spinning (1)H NMR. NMR Biomed; 2008 Nov;21(10):1138-47
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  • [Title] An assessment of the effects of sample ischaemia and spinning time on the metabolic profile of brain tumour biopsy specimens as determined by high-resolution magic angle spinning (1)H NMR.
  • High-resolution magic angle spinning (HRMAS) (1)H NMR of biopsy tissue provides a biochemical profile that has potential diagnostic and prognostic value, and can aid interpretation of the lower-resolution (1)H-NMR spectra obtained in vivo.
  • In particular, the 18% total creatine increase observed is unlikely to be de novo synthesis of creatine.
  • [MeSH-major] Biomarkers, Tumor / analysis. Brain Ischemia / metabolism. Brain Ischemia / pathology. Brain Neoplasms / metabolism. Brain Neoplasms / pathology. Magnetic Resonance Spectroscopy / methods. Specimen Handling / methods
  • [MeSH-minor] Animals. Biopsy / methods. Cell Line, Tumor. Female. Glioma / metabolism. Glioma / pathology. Humans. Protons. Rats. Rats, Wistar. Reproducibility of Results. Sensitivity and Specificity. Spin Labels

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  • [Copyright] Copyright (c) 2008 John Wiley & Sons, Ltd.
  • (PMID = 18666093.001).
  • [ISSN] 0952-3480
  • [Journal-full-title] NMR in biomedicine
  • [ISO-abbreviation] NMR Biomed
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / / C1459/A2592
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Protons; 0 / Spin Labels
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35. Carlson ML, Driscoll CL, Link MJ, Inwards CY, Neff BA, Beatty CW: A hemorrhagic vestibular schwannoma presenting with rapid neurologic decline: a case report. Laryngoscope; 2010;120 Suppl 4:S204
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  • INTRODUCTION: Vestibular schwannomas (VS) account for approximately 8% of all intracranial neoplasms and nearly 80% of all cerebellopontine angle tumors.
  • Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a left sided 2 X 2 cm cerebellopontine angle mass consistent with a vs. Local mass effect resulted in 4th ventricle effacement and hydrocephalus.
  • [MeSH-major] Cerebellopontine Angle / pathology. Hemorrhage / complications. Neuroma, Acoustic / complications

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  • (PMID = 21225802.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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36. Nakamura M, Roser F, Dormiani M, Matthies C, Vorkapic P, Samii M: Facial and cochlear nerve function after surgery of cerebellopontine angle meningiomas. Neurosurgery; 2005 Jul;57(1):77-90; discussion 77-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Facial and cochlear nerve function after surgery of cerebellopontine angle meningiomas.
  • OBJECTIVE: Meningiomas of the cerebellopontine angle (CPA) share a common location, but their site of dural origin and their relationship to surrounding neurovascular structures of the CPA are variable.
  • The clinical presentation and outcome after surgical resection are different because of the diversity of this tumor entity.
  • We report on a series of 421 patients with CPA meningiomas, with special emphasis on the analysis of the preoperative and postoperative facial and cochlear nerve function in relation to the site of dural attachment and main tumor location in the CPA cistern.
  • Among these patients, 32.9% of the tumors originated at the petrous ridge anterior to the inner auditory canal (IAC) (Group 1), 22.2% showed involvement of the IAC (Group 2), 20.2% were located superior to the IAC (Group 3), 11.8% were inferior to the IAC (Group 4), and 12.9% were posterior to the IAC, originating between the IAC and the sigmoid sinus (Group 5).
  • Patients presented with disturbance of Cranial Nerves V-VIII, the lower cranial nerves, and ataxia, depending on the main tumor location.
  • Tumor resection was performed through a suboccipital-retrosigmoidal approach in the semisitting position in 95% of the patients.
  • Total tumor removal (Simpson Grade 1 and 2) was achieved in 85.9% and subtotal removal in 14.1%.
  • The best initial postoperative facial and auditory nerve function was observed in tumors belonging to Groups 3 and 5.
  • CONCLUSION: Although the outcome of facial and cochlear nerve function is different in CPA meningiomas, depending on the topographic classification of these tumors, preservation of the cochlear nerve is possible in every tumor group and should be attempted in every patient with CPA meningioma.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Cerebellopontine Angle / pathology. Cochlear Nerve / physiopathology. Facial Nerve / physiopathology. Meningioma / surgery

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  • (PMID = 15987543.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
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37. Eisen MD, Smith PG, Judy KD, Bigelow DC: Cerebrospinal fluid cytology to aid the diagnosis of cerebellopontine angle tumors. Otol Neurotol; 2006 Jun;27(4):553-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebrospinal fluid cytology to aid the diagnosis of cerebellopontine angle tumors.
  • OBJECTIVE: To determine if cerebrospinal fluid (CSF) cytology can be useful in the workup of patients with internal auditory canal/cerebellopontine angle (IAC/CPA) tumors and facial paralysis to diagnose metastatic disease before surgical intervention.
  • PATIENTS: Patients who presented with or developed facial paralysis and IAC/CPA tumors.
  • In the first patient, excision of the tumor revealed adenocarcinoma.
  • In five of these patients, cytological CSF analysis revealed malignant cells, suggesting a diagnosis of a metastatic lesion rather than acoustic neuroma.
  • A sixth patient had metastatic breast cancer, but negative CSF cytology and a stable CPA tumor after radiation treatment.
  • Two patients who were being conservatively followed up for their IAC/CPA tumor developed a nonprogressive but persistent mild Grade II facial weakness and underwent CSF analysis which tested negative.
  • CONCLUSION: Our experience suggests that patients presenting with IAC/CPA tumors and progressive facial paralysis of House-Brackmann Grade III or greater should have a CSF cytological examination before surgical intervention to evaluate for a malignant process.
  • [MeSH-major] Adenocarcinoma / diagnosis. Cerebellar Neoplasms / diagnosis. Cerebellopontine Angle / pathology. Cerebrospinal Fluid / cytology. Cytological Techniques / methods

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  • (PMID = 16791049.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Brewis S, Baguley DM: Management of tinnitus induced by brainstem and cerebellar infarction associated with complications of cerebello-pontine angle surgery. J Laryngol Otol; 2007 Apr;121(4):393-4
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  • [Title] Management of tinnitus induced by brainstem and cerebellar infarction associated with complications of cerebello-pontine angle surgery.
  • Following surgery in the USA in 1992 to remove a large right cerebello-pontine angle tumour, a 39-year-old woman developed severe brainstem and cerebellar infarction.
  • [MeSH-major] Brain Stem Infarctions / complications. Cerebellar Neoplasms / complications. Cerebellopontine Angle. Cerebral Infarction / complications. Meningioma / complications. Tinnitus / etiology

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  • (PMID = 17403265.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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39. Moreira Jda S, Hass M, Moreira AL, Fleck Jde F, Camargo Jde J: [Reversal of digital clubbing in surgically treated lung cancer patients]. J Bras Pneumol; 2008 Jul;34(7):481-9
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  • [Transliterated title] Regressão do hipocratismo digital em pacientes com câncer de pulmão tratados cirurgicamente.
  • Preoperatively, as well as on postoperative days 7, 18, and 90, the hyponychial angle (HA) and the distal phalangeal depth/interphalangeal depth (DPD/IPD) ratio were determined on profile shadow projections of the index fingers.
  • CONCLUSION: In most lung cancer patients, DC resolves after effective surgical treatment of the tumor, as can occur in patients with other conditions.

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  • (PMID = 18695793.001).
  • [ISSN] 1806-3756
  • [Journal-full-title] Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
  • [ISO-abbreviation] J Bras Pneumol
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
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40. Moradi A, Semnani V, Djam H, Tajodini A, Zali AR, Ghaemi K, Nikzad N, Madani-Civi M: Pathodiagnostic parameters for meningioma grading. J Clin Neurosci; 2008 Dec;15(12):1370-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Meningiomas are usually slow-growing benign tumors, for which complete removal can be difficult and recurrence is an issue.
  • Between January 1997 and December 2006, a total of 4885 intracranial tumors were diagnosed at Shohada Hospital, 378 (7.74%) of which were meningiomas.
  • Convexity meningiomas were most common, followed by meningiomas of the sphenoid ridge and cerebellopontine angle.
  • There was no relationship between the location of the tumor and the histopathological features.
  • Overall, the mitotic count was the most important marker for tumor grade.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningioma / diagnosis

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  • (PMID = 18819804.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] EC 6.3.2.19 / MIB1 ligase, human; EC 6.3.2.19 / Ubiquitin-Protein Ligases
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41. Szaflik JP, Oldak M, Ulinska M, Tesla P, Szaflik J: OCT and in vivo confocal microscopy of a pigmented corneal tumor-like lesion. Ophthalmic Surg Lasers Imaging; 2009 Nov-Dec;40(6):586-8
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  • [Title] OCT and in vivo confocal microscopy of a pigmented corneal tumor-like lesion.
  • A 43-year-old woman presented with a pigmented flat tumor situated at the posterior surface of the cornea nasally in her left eye.
  • Anterior-segment optical coherence tomography revealed that the lesion was similar to the iris leaf, was limited to the cornea, and did not communicate with the iridocorneal angle.
  • The diagnosis of pigmented nevus or retrocorneal membrane was suspected.
  • The authors conclude that anterior-segment optical coherence tomography and in vivo scanning slit confocal microscopy are useful in assessing the microstructure and penetration of pigmented corneal lesions.
  • [MeSH-major] Corneal Diseases / diagnosis. Endothelium, Corneal / pathology. Eye Neoplasms / diagnosis. Microscopy, Confocal / methods. Nevus, Pigmented / diagnosis. Tomography, Optical Coherence / methods
  • [MeSH-minor] Adult. Cell Count. Diagnosis, Differential. Female. Follow-Up Studies. Humans

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  • [Copyright] Copyright 2009, SLACK Incorporated.
  • [ErratumIn] Ophthalmic Surg Lasers Imaging. 2010 Jan-Feb;41(1):144. Ulnska, Magdalena [corrected to Ulinska, Magdalena]
  • (PMID = 19928725.001).
  • [ISSN] 1542-8877
  • [Journal-full-title] Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
  • [ISO-abbreviation] Ophthalmic Surg Lasers Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Rath SA, Moszko S, Schäffner PM, Cantone G, Braun V, Richter HP, Antoniadis G: Accuracy of pedicle screw insertion in the cervical spine for internal fixation using frameless stereotactic guidance. J Neurosurg Spine; 2008 Mar;8(3):237-45
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  • The risk of neurovascular injury in this region is considered high because the diameter of cervical pedicles is very small and their angle of insertion into the vertebral body varies.
  • METHODS: Twenty-seven patients underwent posterior stabilization of the cervical spine for degenerative instability resulting from myelopathy, fracture/dislocation, tumor, rheumatoid arthritis, and pyogenic spondylitis.
  • Screw malplacement was mostly due to a small pedicle diameter that required a steep trajectory angle, which could not be achieved because of anatomical limitation in the exposure of the surgical field.

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  • (PMID = 18312075.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Dobrov A, Arion VB, Kandler N, Ginzinger W, Jakupec MA, Rufińska A, Graf von Keyserlingk N, Galanski M, Kowol C, Keppler BK: The first metal-based paullone derivative with high antiproliferative activity in vitro. Inorg Chem; 2006 Mar 6;45(5):1945-50
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  • The first metal-based paullone has been prepared and characterized by single-crystal X-ray diffraction methods, solid-state cross-polarization magic angle spinning 13C NMR spectroscopy, electrospray ionization mass spectra, and electronic spectra.
  • The gallium complex [GaL2]Cl.2.5H2O, the metal-free ligand (HL), and the starting compound used for the preparation of HL were assessed in vitro for their cytotoxicity in a panel of human tumor cell lines.
  • [MeSH-minor] Crystallography, X-Ray. Drug Screening Assays, Antitumor. Flavonoids / chemistry. Galium / chemistry. Humans. Ligands. Magnetic Resonance Spectroscopy. Metals / chemistry. Molecular Structure. Piperidines / chemistry. Spectrometry, Mass, Electrospray Ionization. Structure-Activity Relationship. Tumor Cells, Cultured

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  • (PMID = 16499355.001).
  • [ISSN] 0020-1669
  • [Journal-full-title] Inorganic chemistry
  • [ISO-abbreviation] Inorg Chem
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Flavonoids; 0 / Ligands; 0 / Metals; 0 / Piperidines; 45AD6X575G / alvocidib
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44. Chen CT, Foo NH, Liu WS, Chen SH: Infusion of human umbilical cord blood cells ameliorates hind limb dysfunction in experimental spinal cord injury through anti-inflammatory, vasculogenic and neurotrophic mechanisms. Pediatr Neonatol; 2008 Jun;49(3):77-83
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  • Behavioral function tests measuring the maximal angle at which an animal could hold onto the inclined plane were conducted on days 1, 4 and 7 after SCI.
  • Serum levels of tumor necrosis factor (TNF)-alpha and interleukin (IL)-10, were assayed.
  • [MeSH-minor] Animals. Glial Cell Line-Derived Neurotrophic Factor / analysis. Hindlimb / physiopathology. Humans. Immunohistochemistry. Interleukin-10 / blood. Motor Activity. Rats. Rats, Sprague-Dawley. Tumor Necrosis Factor-alpha / blood. Vascular Endothelial Growth Factor A / blood

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  • (PMID = 18947003.001).
  • [ISSN] 1875-9572
  • [Journal-full-title] Pediatrics and neonatology
  • [ISO-abbreviation] Pediatr Neonatol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Singapore
  • [Chemical-registry-number] 0 / Glial Cell Line-Derived Neurotrophic Factor; 0 / Tumor Necrosis Factor-alpha; 0 / Vascular Endothelial Growth Factor A; 130068-27-8 / Interleukin-10
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45. Ferda J, Kastner J, Mukensnabl P, Choc M, Horemuzová J, Ferdová E, Kreuzberg B: Diffusion tensor magnetic resonance imaging of glial brain tumors. Eur J Radiol; 2010 Jun;74(3):428-36
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  • [Title] Diffusion tensor magnetic resonance imaging of glial brain tumors.
  • AIM: To evaluate the author's experience with the use of diffusion tensor magnetic resonance imaging (DTI) on patients with glial tumors.
  • METHODS: A retrospective evaluation of a group of 24 patients with glial tumors was performed.
  • There were eight patients with Grade II, eight patients with Grade III and eight patients with Grade IV tumors with a histologically proven diagnosis.
  • The white matter FA changes were assessed within the tumorous tissue, on the tumorous borderline and in the normally appearing white matter adjacent to the tumor.
  • A three-dimensional model of the white matter tract was created to demonstrate the space relationship of the tumor and the capsula interna or corpus callosum in each case using the following fiber tracing parameters: FA step 0.25 and a tensor declination angle of 45 gr.
  • RESULTS: A uniform homogenous structure with sharp demargination of the Grade II tumors and the wide rim of the intermedial FA in all Grade III tumors respectively, were found during the evaluation of the FA maps.
  • In Grade IV tumors a variable demargination was noted on the FA maps.
  • The sensitivity and specificity for the discrimination of low- and high-grade glial tumors using FA maps was revealed to be 81% and 87% respectively.
  • CONCLUSION: Although the evaluation of the fractional anisotropy maps is not sufficient for glioma grading, the combination of the contrast enhancement pattern and fractional anisotropy maps evaluation improves the possibility of distinguishing low- and high-grade glial tumors.

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  • [Copyright] Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19394780.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
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46. Vávrová M, Pelikán A, Dostalík J, Martínek L, Guniková P, Gunka I: [A contribution of the anorectal angle measurement according to Schiessel to assessment of the safe distance of the inferior resection line in the rectal carcinomas surgical procedures]. Rozhl Chir; 2006 Feb;85(2):78-81
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  • [Title] [A contribution of the anorectal angle measurement according to Schiessel to assessment of the safe distance of the inferior resection line in the rectal carcinomas surgical procedures].
  • Especially when the tumor is located in the middle and distal third of the rectum and the surgeons aim to conduct a sphincter-saving procedure, the pre-operative diagnostics is a pre-requisite for a successful treatment.
  • The authors aim to inform the medical community on a non-traditional and rarely used examination method of the anorectal angle prior to surgical procedures of the rectal carcinomas.

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  • (PMID = 16626016.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
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47. Hori T, Okada Y, Maruyama T, Chernov M, Attia W: Endoscope-controlled removal of intrameatal vestibular schwannomas. Minim Invasive Neurosurg; 2006 Feb;49(1):25-9
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  • The use of endoscopes for surgery of the cerebellopontine angle tumors is steadily obtaining widespread acceptance.
  • A bayonet-style rigid endoscope with 70 degrees angle of view and 4 mm outer diameter was found to be optimal for observation of the internal auditory canal.
  • Its insertion in the cerebellopontine cistern should be preferably done under control through an operating microscope.
  • Use of the endoscope permitted removal of the neoplasm from the most lateral part of the internal auditory canal and identification of the nerve of tumor origin.
  • In total, 28 tumors underwent total removal, and anatomical preservation of the facial nerve was attained in 31 cases.
  • In 8 out of 16 patients, who showed serviceable hearing before surgery, this was preserved after tumor removal.
  • [MeSH-major] Microsurgery / instrumentation. Neoplasm Recurrence, Local / surgery. Neuroendoscopes. Neuroma, Acoustic / surgery
  • [MeSH-minor] Adult. Aged. Cadaver. Cerebellopontine Angle. Facial Nerve / physiopathology. Feasibility Studies. Female. Hearing / physiology. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 16547878.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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48. Nagahama K, Ohya Y, Ouchi T: Suppression of cell and platelet adhesion to star-shaped 8-armed poly(ethylene glycol)-poly(L-lactide) block copolymer films. Macromol Biosci; 2006 Jun 16;6(6):412-9
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  • To explore the potential of a star-shaped 8-armed poly(ethylene glycol)35K-block-poly(L-lactide)37K (8-armed PEG35K-b-PLLA37K: M(n) of PEG = 35 000, M(n) of PLLA = 37 000) film as a novel bioabsorbable adhesion-prevention membrane, the water structure, surface contact angle, protein adsorption, and cell and platelet anti-adhesion properties of such a hydrated film are investigated.
  • [MeSH-minor] Absorption. Adsorption. Animals. Biocompatible Materials. Cattle. Cell Culture Techniques. Cell Line, Tumor. Mice. Microscopy, Electron, Scanning. Models, Biological. Polymers / chemical synthesis. Polymers / chemistry. Water / chemistry

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  • (PMID = 16741900.001).
  • [ISSN] 1616-5187
  • [Journal-full-title] Macromolecular bioscience
  • [ISO-abbreviation] Macromol Biosci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / Polymers; 059QF0KO0R / Water; 30IQX730WE / Polyethylene Glycols
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49. Chen AP, Albers MJ, Cunningham CH, Kohler SJ, Yen YF, Hurd RE, Tropp J, Bok R, Pauly JM, Nelson SJ, Kurhanewicz J, Vigneron DB: Hyperpolarized C-13 spectroscopic imaging of the TRAMP mouse at 3T-initial experience. Magn Reson Med; 2007 Dec;58(6):1099-106
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  • To investigate differences in cellular bioenergetics between normal prostate epithelial cells and prostate tumor cells, in vivo MR spectroscopic (MRS) studies with non-proton nuclei, such as (13)C, in the TRAMP model would be extremely useful.
  • In this transgenic mouse study, this method was applied using a double spin-echo (DSE) pulse sequence with a small-tip-angle excitation RF pulse, hyperbolic-secant refocusing pulses, and a flyback echo-planar readout trajectory for fast (10-14 s) MRSI of (13)C pyruvate (pyr) and its metabolic products at 0.135 cm(3) nominal spatial resolution.
  • Elevated (13)C lactate (lac) was observed in both primary and metastatic tumors, demonstrating the feasibility of studying cellular bioenergetics in vivo with DNP hyperpolarized (13)C MRSI.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Biomarkers, Tumor / metabolism. Magnetic Resonance Spectroscopy / methods. Prostatic Neoplasms / metabolism. Prostatic Neoplasms / pathology

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17969006.001).
  • [ISSN] 0740-3194
  • [Journal-full-title] Magnetic resonance in medicine
  • [ISO-abbreviation] Magn Reson Med
  • [Language] eng
  • [Grant] United States / NIBIB NIH HHS / EB / R01 EB007588; United States / NIBIB NIH HHS / EB / R21 EB005363
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carbon Isotopes
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50. Franco-Vidal V, Négrevergne M, Darrouzet V: [Vertigo and pathology of the cerebello-pontine angle]. Rev Laryngol Otol Rhinol (Bord); 2005;126(4):223-6
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  • [Title] [Vertigo and pathology of the cerebello-pontine angle].
  • [Transliterated title] Vertiges et pathologie de l'angle ponto-cérébelleux.
  • Many pathologies of the cerebello-pontine angle can induce vertigo or dizziness.
  • Usually they are due to benign or malignant tumors.
  • Finally very big tumors can be compressive on the cerebellum or on the brainstem inducing also dizziness.
  • Vertigo is often an important symptom of cerebello-pontine angle tumors.
  • In association with others it will guide the diagnosis.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Vertigo / etiology

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  • (PMID = 16496548.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 16
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51. Phillips DJ, Kobylarz EJ, De Peralta ET, Stieg PE, Selesnick SH: Predictive factors of hearing preservation after surgical resection of small vestibular schwannomas. Otol Neurotol; 2010 Dec;31(9):1463-8
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  • PATIENTS: Forty patients with serviceable hearing preoperatively who underwent a potentially hearing sparing procedure for resection of small vestibular schwannoma (extending 1 cm or less into the cerebellopontine angle).
  • Potential predictive factors of hearing preservation included patient demographics, tumor characteristics, audiometric data, and intraoperative brainstem auditory evoked response (BAER) monitoring.
  • Patient age, sex, preoperative hearing status, tumor size, laterality, extent of internal auditory canal involvement, surgical approach, wave V latency, and wave V amplitude were not predictive of hearing preservation.

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  • (PMID = 21113983.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Santoro J, Kriminski S, Lovelock DM, Rosenzweig K, Mostafavi H, Amols HI, Mageras GS: Evaluation of respiration-correlated digital tomosynthesis in lung. Med Phys; 2010 Mar;37(3):1237-45
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  • The DTS images were reconstructed in planes at different depths through the patient and normal to a user-selected angle close to the center of the arc.
  • Evaluation of RC-DTS in eight tumors shows visible reduction in image blur caused by the respiratory motion.
  • It also allows the visualization of tumor motion extent.
  • Comparison of RC-DTS with respiration-correlated cone-beam CT in determining tumor position, motion extent and displacement between treatment sessions shows agreement in most cases within 2-3 mm, comparable in magnitude to the intraobserver repeatability of the measurement.

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  • (PMID = 20384261.001).
  • [ISSN] 0094-2405
  • [Journal-full-title] Medical physics
  • [ISO-abbreviation] Med Phys
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / T32 CA061801; United States / NCI NIH HHS / CA / R01CA126993; United States / NCI NIH HHS / CA / P01 CA059017; United States / NCI NIH HHS / CA / R01 CA126993; United States / NCI NIH HHS / CA / P01CA59017; United States / NCI NIH HHS / CA / T32CA61801
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2905456
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53. House WF, Shelton C: Middle fossa approach for acoustic tumor removal. 1992. Neurosurg Clin N Am; 2008 Apr;19(2):279-88, vi
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  • [Title] Middle fossa approach for acoustic tumor removal. 1992.
  • The middle fossa approach is useful for the removal of small acoustic tumors when hearing preservation is possible.
  • Because access to the posterior fossa is limited, the middle fossa approach is most appropriate for tumors with less than 5 mm extension into the cerebellopontine angle.
  • With the introduction of gadolinium-enhanced magnetic resonance imaging, very small acoustic tumors are diagonosed more frequently, and the middle fossa approach is well-suited for the removal of these tumors.

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  • (PMID = 18534340.001).
  • [ISSN] 1558-1349
  • [Journal-full-title] Neurosurgery clinics of North America
  • [ISO-abbreviation] Neurosurg. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Biography; Classical Article; Historical Article; Journal Article
  • [Publication-country] United States
  • [Personal-name-as-subject] House WF; Shelton C
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54. Korkut N, Işildak H, Tuskan K, Oğreden S: [Lipoma of the cerebellopontine angle: two cases report and review of literature]. Kulak Burun Bogaz Ihtis Derg; 2009 Jul-Aug;19(4):207-11
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  • [Title] [Lipoma of the cerebellopontine angle: two cases report and review of literature].
  • Here we report two cases with cerebellopontine angle lipoma.
  • Cerebellopontine angle lipomas previously reported in the literature were reviewed.
  • The median tumor size was 10.26 (range: 1 to 26) mm.
  • It was noted that these tumors are most frequently associated with hearing loss (56%) and tinnitus (40%), while 9% demonstrate no symptoms.
  • In our cases, the tumor sizes were 7 x 4 and 5 x 3 mm.
  • Histopathological diagnosis is rarely necessary with the widespread use of magnetic resonance imaging.
  • Because of the potential for significant morbidity with resection of these lesions, conservative follow-up is the best approach for cerebellopontine angle lipoma.
  • [MeSH-major] Cerebellopontine Angle / pathology. Lipoma / pathology

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  • (PMID = 19860636.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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55. Shields CL, Thangappan A, Hartzell K, Valente P, Pirondini C, Shields JA: Combined hamartoma of the retina and retinal pigment epithelium in 77 consecutive patients visual outcome based on macular versus extramacular tumor location. Ophthalmology; 2008 Dec;115(12):2246-2252.e3
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  • [Title] Combined hamartoma of the retina and retinal pigment epithelium in 77 consecutive patients visual outcome based on macular versus extramacular tumor location.
  • The tumors had the following characteristics: a mean diameter of 7.6 mm, a mean thickness of 1.9 mm, round (n = 52; 66%) or curvilinear (n = 27; 34%) configuration, and other features including intralesional corkscrew vessels (n = 51; 65%), feeding straight vessels (n = 50; 63%), retinal traction (n = 64; 81%), fibrosis/gliosis (n = 36; 46%), and exudation (n = 10; 13%).
  • Referring diagnosis was unknown (n = 40; 51%) or incorrect (n = 19; 24%) as retinoblastoma (n = 4), astrocytoma (n = 1), toxocariasis (n = 2), choroidal nevus (n = 5), melanoma (n = 6), and hemangioma (n = 1).
  • The mean initial visual acuity by logarithm of the minimum angle of resolution (Snellen) for macular (n = 29) versus extramacular (n = 28) tumors was 1.2 (20/320) versus 0.61 (20/80) and at 4 years was 1.72 (20/800) versus 0.79 (20/125).
  • By univariate analysis, the most important factors predictive of poor visual acuity included macular location and clock hour meridian of the tumor.
  • CONCLUSIONS: Combined hamartoma of the retina and RPE can cause profound visual acuity loss, particularly with macular tumors.

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  • (PMID = 18995912.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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56. Bennett M, Haynes DS: Surgical approaches and complications in the removal of vestibular schwannomas. 2007. Neurosurg Clin N Am; 2008 Apr;19(2):331-43, vii
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  • Vestibular schwannomas are benign tumors that usually originate from the balance portion of cranial nerve VIII.
  • Although the ultimate goal in treatment of vestibular schwannomas is preservation of life, the best option for each patient depends on symptoms, tumor size, tumor location, and the patient's general health and age.
  • Surgical exposure of the cerebellopontine angle for removal of vestibular schwannomas can be performed safely via a translabyrinthine, retrosigmoid, and middle fossa approach.
  • The goal of surgery is complete eradication of tumor with preservation of hearing and facial nerve function when possible.

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  • (PMID = 18534343.001).
  • [ISSN] 1558-1349
  • [Journal-full-title] Neurosurgery clinics of North America
  • [ISO-abbreviation] Neurosurg. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Biography; Classical Article; Historical Article; Journal Article
  • [Publication-country] United States
  • [Personal-name-as-subject] Bennett M; Haynes DS
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57. Shirai S, Sato M, Suwa K, Kishi K, Shimono C, Sonomura T, Kawai N, Tanihata H, Minamiguchi H, Nakai M: Feasibility and efficacy of single photon emission computed tomography-based three-dimensional conformal radiotherapy for hepatocellular carcinoma 8 cm or more with portal vein tumor thrombus in combination with transcatheter arterial chemoembolization. Int J Radiat Oncol Biol Phys; 2010 Mar 15;76(4):1037-44
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  • [Title] Feasibility and efficacy of single photon emission computed tomography-based three-dimensional conformal radiotherapy for hepatocellular carcinoma 8 cm or more with portal vein tumor thrombus in combination with transcatheter arterial chemoembolization.
  • PURPOSE: To assess the feasibility and efficacy of single photon emission computed tomography-based three-dimensional conformal radiotherapy (SPECT-B 3D-CRT) for large hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT).
  • SPECT, using Tc-99m-galactosyl human serum albumin, was used in radiation treatment planning to explore the optimal irradiation beam angle.
  • Clinical target volume (CTV) included the main tumor and PVTT.
  • The cumulative non-progression rates of PVTT and PVTT plus main tumor were 78.0 and 43.2%, respectively.
  • [MeSH-minor] Aged. Aged, 80 and over. Combined Modality Therapy / methods. Feasibility Studies. Female. Humans. Liver / radionuclide imaging. Liver Cirrhosis / radionuclide imaging. Male. Middle Aged. Portal Vein. Prospective Studies. Radiopharmaceuticals. Radiotherapy Dosage. Survival Rate. Technetium Tc 99m Aggregated Albumin. Technetium Tc 99m Pentetate. Tumor Burden

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  • [Copyright] Crown Copyright 2010. Published by Elsevier Inc. All rights reserved.
  • (PMID = 19540053.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0 / Technetium Tc 99m Aggregated Albumin; 0 / technetium Tc 99m DTPA-galactosyl-human serum albumin; VW78417PU1 / Technetium Tc 99m Pentetate
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58. Yakoub D, Keun HC, Goldin R, Hanna GB: Metabolic profiling detects field effects in nondysplastic tissue from esophageal cancer patients. Cancer Res; 2010 Nov 15;70(22):9129-36
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  • Based on the "field cancerization" hypothesis that tumors arise within a transformed field with an altered biochemical phenotype, we sought to test if metabolic profiling could differentiate between histologically normal tissue from individuals with and without esophageal cancer.
  • Using 1H magic angle spinning-nuclear magnetic resonance spectroscopy of intact tissue, we generated metabolic profiles of tumor tissue, proximal histologically normal mucosa from cancer patients (PHINOM), and proximal histologically normal mucosa from a control group.
  • Whereas 26% and 12% of the spectral profile regions were uniquely discriminating tumor or control tissue, respectively, 5% of the profile exhibited a significant progressive change in signal intensity from controls to PHINOM to tumor.
  • [MeSH-minor] Barrett Esophagus / diagnosis. Barrett Esophagus / metabolism. Cell Transformation, Neoplastic / metabolism. Diagnosis, Differential. Esophagus / metabolism. Esophagus / pathology. Female. Glutamic Acid / metabolism. Humans. Inosine / metabolism. Inositol / metabolism. Magnetic Resonance Spectroscopy. Male. Middle Aged. Multivariate Analysis. Phosphorylcholine / metabolism. Regression Analysis. Sensitivity and Specificity

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  • [Copyright] Copyright © 2010 AACR.
  • (PMID = 20884633.001).
  • [ISSN] 1538-7445
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 107-73-3 / Phosphorylcholine; 3KX376GY7L / Glutamic Acid; 4L6452S749 / Inositol; 5A614L51CT / Inosine
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59. Oluigbo CO, Cooke SR, Flynn PA, Choudhari KA: Primary malignant melanoma of the cerebellopontine angle: a diagnostic dilemma: case report. Neurosurgery; 2006 Dec;59(6):E1336; discussion E1336
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  • [Title] Primary malignant melanoma of the cerebellopontine angle: a diagnostic dilemma: case report.
  • OBJECTIVE: To present a rare case of a primary malignant melanoma of the central nervous system presenting as a cerebellopontine angle (CPA) tumor and to delineate aspects of the clinical presentation and magnetic resonance imaging scan characteristics that may suggest this unusual condition.
  • Brain magnetic resonance imaging scans showed a right-sided CPA tumor exhibiting shortening of T1 and T2 relaxation times, but overall neuroradiological features were not consistent with any commonly occurring CPA tumors.
  • CONCLUSION: Correlation of clinical and imaging findings offer the most important clues in the diagnosis of such unusual primary malignant tumors of the CPA.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellopontine Angle / pathology. Cerebellopontine Angle / surgery. Melanoma / pathology. Melanoma / surgery
  • [MeSH-minor] Aged. Craniotomy. Diagnosis, Differential. Humans. Male

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  • (PMID = 17277669.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Shukla D, Behari S, Jaiswal AK, Banerji D, Tyagi I, Jain VK: Tentorial meningiomas: operative nuances and perioperative management dilemmas. Acta Neurochir (Wien); 2009 Sep;151(9):1037-51
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  • METHODS: Thirty-seven patients (28 primary [supratentorial (2), infratentorial (20) and both (6)] and nine complex [cerebellopontine (CP) angle (5) and petroclival (4)] underwent surgery using the occipital transtentorial, supracerebellar infratentorial, subtemporal transtentorial, bioccipital suboccipital, midline suboccipital, retrosigmoid, and combined pre and retrosigmoid approaches.
  • One patient had recurrence and four others underwent resurgery for residual tumor.
  • Two patients with petroclival lesions died due to aspiration pneumonitis and meningitis, respectively; one with CP angle TM presented in a poor general condition and expired following emergency ventriculoperitoneal shunt and subsequent definite surgery.
  • Meticulously preserving venous sinuses is important since the risk of venous infarction cannot be predicted even with radiological good venous collaterization and apparent venous sinus blockade by tumor.
  • Laterally situated tumors carry a better prognosis when compared to the medially situated ones.
  • Leaving a small residual tumor in an effort to preserve important neurovascular structures does not obviate the expectation of a good long-term prognosis with minimal morbidity and low recurrence rates.
  • [MeSH-minor] Adolescent. Adult. Brain Infarction / prevention & control. Brain Stem / blood supply. Brain Stem / pathology. Brain Stem / surgery. Cerebellum / blood supply. Cerebellum / pathology. Cerebellum / surgery. Child. Child, Preschool. Cranial Fossa, Posterior / pathology. Cranial Fossa, Posterior / radiography. Cranial Fossa, Posterior / surgery. Cranial Sinuses / anatomy & histology. Cranial Sinuses / surgery. Decompression, Surgical / methods. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Neurosurgical Procedures / methods. Prospective Studies. Young Adult

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  • (PMID = 19572103.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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61. Plathow C, Schoebinger M, Herth F, Tuengerthal S, Meinzer HP, Kauczor HU: Estimation of pulmonary motion in healthy subjects and patients with intrathoracic tumors using 3D-dynamic MRI: initial results. Korean J Radiol; 2009 Nov-Dec;10(6):559-67
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  • [Title] Estimation of pulmonary motion in healthy subjects and patients with intrathoracic tumors using 3D-dynamic MRI: initial results.
  • OBJECTIVE: To estimate a new technique for quantifying regional lung motion using 3D-MRI in healthy volunteers and to apply the technique in patients with intra- or extrapulmonary tumors.
  • MATERIALS AND METHODS: Intraparenchymal lung motion during a whole breathing cycle was quantified in 30 healthy volunteers using 3D-dynamic MRI (FLASH [fast low angle shot] 3D, TRICKS [time-resolved interpolated contrast kinetics]).
  • The patients with NSCLC showed a local lack of lung motion in the area of the tumor.
  • In the patients with MPM, there was global diminished motion of the tumor bearing hemithorax, which improved significantly after chemotherapy (CHT) (assessed by the 2D- and 3D-techniques) (p < 0.01).

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  • (PMID = 19885311.001).
  • [ISSN] 2005-8330
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2770821
  • [Keywords] NOTNLM ; Biomechanics / Dynamic MRI / Intraparenchymal lung motion / Pleural mesothelioma / Tumor
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62. Lee SH, Rhee BA, Choi SK, Koh JS, Lim YJ: Cerebellopontine angle tumors causing hemifacial spasm: types, incidence, and mechanism in nine reported cases and literature review. Acta Neurochir (Wien); 2010 Nov;152(11):1901-8
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  • [Title] Cerebellopontine angle tumors causing hemifacial spasm: types, incidence, and mechanism in nine reported cases and literature review.
  • OBJECTIVE: Although hemifacial spasm is usually caused by vascular compression around the root exit zone of the facial nerve, it is sometimes brought on by a cerebellopontine angle tumor.
  • We reviewed and analyzed data from past experience with hemifacial spasm induced by cerebellopontine angle tumors.
  • METHODS: Nine patients of a total 2,050, who had presented with hemifacial spasms associated with cerebellopontine angle tumors between 1986 and 2009, were reviewed.
  • RESULTS: Two vestibular schwannomas, five meningiomas, and two epidermoid tumors were included in this study.
  • With respect to the pathogenesis of hemifacial spasms, offending vessels were found in six patients, tumor encasement of the facial nerve in one patient, hypervascular tumor compression of the facial nerve without offending vessels in one patient, and a huge tumor compressing the brain stem and, thus, contralateral facial nerve compression in one patient.
  • Hemifacial spasm was resolved in seven patients, whereas in two patients with a vestibular schwannoma and an epidermoid tumor, it improved transiently and then recurred in a month.
  • CONCLUSIONS: Each type of tumor had different characteristics with respect to the induction of hemifacial spasm; therefore, it is suggested that neurosurgeons, who are planning surgeries both for the purposes of relieving hemifacial spasm and removal of cerebellopontine angle tumor, should thoroughly prepare appropriate approaches and specific dissecting strategies according to each causative lesion.

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  • (PMID = 20845049.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
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63. Karampelas I, Alberico RA, Plunkett RJ, Fenstermaker RA: Intratumoral hemorrhage after remote subtotal microsurgical resection and gamma knife radiosurgery for vestibular schwannoma. Acta Neurochir (Wien); 2007 Mar;149(3):313-6; discussion 316-7
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  • Although rare, it is apparent that bleeding into a vestibular schwannoma remains a possibility, even after the tumor has responded favorably to GKS.
  • [MeSH-major] Cerebral Hemorrhage / diagnosis. Microsurgery. Neuroma, Acoustic / surgery. Postoperative Hemorrhage / diagnosis. Radiosurgery
  • [MeSH-minor] Cerebellopontine Angle / pathology. Follow-Up Studies. Hemosiderin / metabolism. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm, Residual / diagnosis

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  • (PMID = 17273886.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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64. Okamoto K, Furusawa T, Ishikawa K, Sasai K, Tokiguchi S: Focal T2 hyperintensity in the dorsal brain stem in patients with vestibular schwannoma. AJNR Am J Neuroradiol; 2006 Jun-Jul;27(6):1307-11
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  • METHODS: We retrospectively reviewed the postoperative MR images of 53 patients with cerebellopontine angle tumor.
  • Surgical and histopathologic diagnosis was vestibular schwannoma (41/53 = 77%), meningioma (7/53 = 13%), epidermoid cyst (3/53 = 6%), glioma with exophytic growth (1/53 = 2%), and chordoma (1/53 = 2%).
  • RESULTS: A tiny area of hyperintensity was observed at the lateral angle of the fourth ventricle floor in 6 patients (3 men, 3 women; age range, 24-54 years; mean age, 43 years) with vestibular schwannoma larger than 2 cm in maximal diameter on both FSE T2-weighted and CISS images.
  • If such hyperintensity is seen in a patient with a large cerebellopontine angle tumor, a diagnosis of vestibular schwannoma is suggested.
  • [MeSH-major] Brain Stem / pathology. Magnetic Resonance Imaging. Neuroma, Acoustic / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellopontine Angle. Female. Humans. Male. Middle Aged

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  • (PMID = 16775286.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Preuss SF, Wittekindt C, Klussmann JP, Guntinas-Lichius O, Beutner D, Reineck S, Hüttenbrink KB: [Indolent neck tumour. A 47 year old patient with a painless tumour in the area of the left mandibular angle]. HNO; 2005 Oct;53(10):876-8
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  • [Title] [Indolent neck tumour. A 47 year old patient with a painless tumour in the area of the left mandibular angle].
  • [Transliterated title] Indolenter Halstumor. 47-jährige Patientin mit schmerzlosem Tumor im Bereich des linken Kieferwinkels.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Mandible / diagnostic imaging. Mandible / pathology. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Mandibular Neoplasms / complications. Mandibular Neoplasms / diagnosis. Pain / etiology. Radiography

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  • (PMID = 15703880.001).
  • [ISSN] 0017-6192
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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66. Radcliffe NM, Finger PT: Eye cancer related glaucoma: current concepts. Surv Ophthalmol; 2009 Jan-Feb;54(1):47-73
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  • Mechanisms include direct invasion, infiltration, or seeding of the aqueous outflow structures as well as indirect processes, such as compressive angle closure and anterior segment neovascularization.
  • Treatment options typically depend upon the tumor type (primary or secondary), its location, and mechanism of glaucoma.
  • Clearly, prompt diagnosis and management of eye cancer-related glaucoma offers an opportunity to both preserve vision and the patient's life.

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  • (PMID = 19171210.001).
  • [ISSN] 0039-6257
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 249
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67. Khoddami M, Gholampour Shahaboddini R: Choroid plexus papilloma of the cerebellopontine angle. Arch Iran Med; 2010 Nov;13(6):552-5
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  • [Title] Choroid plexus papilloma of the cerebellopontine angle.
  • The cerebellopontine angle is an extremely rare site for the growth of a choroid plexus papilloma.
  • The clinicoradiological diagnosis of this tumor in the cerebellopontine angle is difficult because of its rarity in addition to a nonspecific clinical presentation and radiological features.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Papilloma, Choroid Plexus / pathology

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  • (PMID = 21039014.001).
  • [ISSN] 1735-3947
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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68. Shiobara R, Ohira T, Inoue Y, Kanzaki J, Kawase T: Extended middle cranial fossa approach for vestibular schwannoma: technical note and surgical results of 896 operations. Prog Neurol Surg; 2008;21:65-72
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  • With this approach, the operative field can be extended according to tumor size and the facial and cochlear nerves can be preserved more easily with cooperation between the neurosurgeon and ENT surgeon.
  • In the 760 initially operated vestibular schwannomas with total removal of the tumor, facial nerves were anatomically preserved in 715 or 94.1% of the cases.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Cerebellopontine Angle. Cranial Fossa, Middle / surgery. Neuroma, Acoustic / surgery. Neurosurgical Procedures / methods

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  • (PMID = 18810200.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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69. Meyers SP, Khademian ZP, Biegel JA, Chuang SH, Korones DN, Zimmerman RA: Primary intracranial atypical teratoid/rhabdoid tumors of infancy and childhood: MRI features and patient outcomes. AJNR Am J Neuroradiol; 2006 May;27(5):962-71
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  • [Title] Primary intracranial atypical teratoid/rhabdoid tumors of infancy and childhood: MRI features and patient outcomes.
  • BACKGROUND AND PURPOSE: Primary atypical teratoid/rhabdoid tumors (AT/RTs) are rare malignant intracranial neoplasms, usually occurring in young children.
  • The objectives of this study were to characterize the MR imaging features and locations of primary intracranial AT/RTs, to determine the frequency of disseminated disease in the central nervous system (CNS) at diagnosis and postoperatively, and to assess patient outcomes.
  • METHODS: The preoperative cranial MR images of 13 patients with AT/RTs were retrospectively reviewed for evaluation of lesion location, size, MR signal intensity and enhancement characteristics, and the presence of disseminated intracranial tumor.
  • Postoperative MR images of the head and spine for 17 patients were reviewed for the presence of locally recurrent or residual tumor and disseminated neoplasm.
  • The single primary extra-axial lesion was located in the cerebellopontine angle cistern.
  • A germ-line mutation of the hSNF5/INI1 tumor-suppressor gene was responsible for the simultaneous occurrence of an intracranial AT/RT and a malignant renal rhabdoid tumor in a 4-month-old patient.
  • Mean tumor sizes were 3.6 x 3.8 x 3.9 cm.
  • The fraction of tumor volume showing enhancement was greater than two thirds in 58%, between one third and two thirds in 33%, and less than one third in 9%.
  • Disseminated tumor in the leptomeninges was seen with MR imaging in 24% of patients at diagnosis/initial staging and occurred in another 35% from 4 months to 2.8 years (mean, 1.1 years) after surgery and earlier imaging examinations with negative findings.
  • Patients with MR imaging evidence of disseminated leptomeningeal tumor had a median survival rate of 16 months compared with 149 months for those without disseminated tumor (P < .004, logrank test).
  • Poor prognosis is associated with MR imaging evidence of disseminated leptomeningeal tumor.
  • [MeSH-major] Brain Neoplasms / diagnosis. Magnetic Resonance Imaging. Rhabdoid Tumor / diagnosis. Teratoma / diagnosis


70. Chang YW, Kwon KH, Choi DL, Lee DW, Lee MH, Lee HK, Yang SB, Kim Y, Seo DY: Magnetic resonance imaging of breast cancer and correlation with prognostic factors. Acta Radiol; 2009 Nov;50(9):990-8
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  • MATERIAL AND METHODS: A total of 136 patients with 151 breast cancers underwent 1.5T dynamic MR imaging with the use of a dynamic T1-weighted three-dimensional fast low-angle shot (FLASH) subtraction imaging technique.
  • Pathological prognostic factors were correlated with MR imaging characteristics, including tumor size, histological grade, lymph node status, expression of estrogen receptor (ER), expression of progesterone receptor (PR), expression of c-erbB2, determination of Ki-67 index, and microvascular density (MVD), using univariate and multivariate statistical analyses.
  • RESULTS: Based on univariate and multivariate analyses, spiculated tumor margins correlated significantly with lower histological grade (I-II) and positive PR expression.
  • Rim enhancement was significantly correlated with high histological grade, presence of axillary lymph node metastasis, large tumor size, increased Ki-67 index, and increased MVD.

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  • (PMID = 19863408.001).
  • [ISSN] 1600-0455
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Contrast Media; 0 / Ki-67 Antigen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 84F6U3J2R6 / gadodiamide; EC 2.7.10.1 / Receptor, ErbB-2; K2I13DR72L / Gadolinium DTPA
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71. Schöler E, Winterhalter S: [Panuveitis with an iris tumor in the chamber angle]. Ophthalmologe; 2008 Jan;105(1):70-2
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  • [Title] [Panuveitis with an iris tumor in the chamber angle].
  • [MeSH-major] Iris Neoplasms / complications. Iris Neoplasms / diagnosis. Panuveitis / complications. Panuveitis / diagnosis. Sarcoidosis / complications. Sarcoidosis / diagnosis

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  • (PMID = 17457589.001).
  • [ISSN] 0941-293X
  • [Journal-full-title] Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
  • [ISO-abbreviation] Ophthalmologe
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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72. Jakob B, Splinter J, Taucher-Scholz G: Positional stability of damaged chromatin domains along radiation tracks in mammalian cells. Radiat Res; 2009 Apr;171(4):405-18
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  • We addressed the influence of lesion density on gamma-H2AX formation and the mobility of damaged chromatin sites by using low-angle irradiation of cell monolayers with low-energy carbon or uranium ions.

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  • (PMID = 19397441.001).
  • [ISSN] 0033-7587
  • [Journal-full-title] Radiation research
  • [ISO-abbreviation] Radiat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chromatin; 0 / Intracellular Signaling Peptides and Proteins; 0 / Replication Protein A; 0 / TP53BP1 protein, human
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73. Borgan E, Sitter B, Lingjærde OC, Johnsen H, Lundgren S, Bathen TF, Sørlie T, Børresen-Dale AL, Gribbestad IS: Merging transcriptomics and metabolomics--advances in breast cancer profiling. BMC Cancer; 2010;10:628
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  • BACKGROUND: Combining gene expression microarrays and high resolution magic angle spinning magnetic resonance spectroscopy (HR MAS MRS) of the same tissue samples enables comparison of the transcriptional and metabolic profiles of breast cancer.
  • Three subgroups of luminal A tumors were identified based on hierarchical clustering of the HR MAS MR spectra.
  • The samples in one of the subgroups, designated A2, showed significantly lower glucose and higher alanine levels than the other luminal A samples, suggesting a higher glycolytic activity in these tumors.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cell Line, Tumor. Female. Humans. Magnetic Resonance Spectroscopy / methods. Middle Aged. Oligonucleotide Array Sequence Analysis

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  • (PMID = 21080935.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2996395
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74. Petscavage JM, Fink JR, Chew FS: Cerebellopontine angle meningioma presenting with hearing loss. Radiol Case Rep; 2010;5(2):434
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  • [Title] Cerebellopontine angle meningioma presenting with hearing loss.
  • We present the case of a 48-year-old woman with a cerebellopontine angle meningioma who presented with sensorineural hearing loss.
  • Hearing loss resulting from cerebellopontine angle tumor is most commonly caused by vestibular schwannomas, which arise directly from the sheath of the vestibular nerve (VIII) in the internal auditory canal.
  • Our case provides a review of magnetic resonance imaging features that aid in differentiation of enhancing cerebellopontine angle masses that can have similar clinical presentations.

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  • (PMID = 27307863.001).
  • [ISSN] 1930-0433
  • [Journal-full-title] Radiology case reports
  • [ISO-abbreviation] Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4898224
  • [Keywords] NOTNLM ; CT, computed tomography / MRI, magnetic resonance imaging / cerebellopontine angle, (CPA) / internal auditory canal, (IAC) / vestibular schwannoma, (VS)
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75. Weinstein JS, Burchiel KJ: Dandy'S disc. Neurosurgery; 2009 Jul;65(1):201-5; discussion 205
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  • He is perhaps best known for his scientific contributions to our understanding of cerebrospinal fluid and pituitary gland physiology and his clinical contributions of ventriculography, cerebellopontine angle approaches for a variety of posterior fossa pathology, and the first clipping of a cerebral aneurysm.
  • He published a thorough clinical, operative, and pathological description in a 1929 Archives of Surgery article, titled "Loose Cartilage from Intervertebral Disk Simulating Tumor of the Spinal Cord."

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  • (PMID = 19574843.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article
  • [Publication-country] United States
  • [Personal-name-as-subject] Dandy WE
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76. Kawamura K, Yajima H, Kobata Y, Murata K, Shigematsu K, Maegawa N, Takakura Y: Wrist arthrodesis with vascularized fibular grafting. J Reconstr Microsurg; 2009 Nov;25(8):501-5
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  • Five patients had defects resulting from excision of a giant cell tumor at the distal radius, and one patient had a defect after debridement of a chronic infection.
  • Measurement of postoperative roentgenograms revealed that the average of fixed wrist angle was 13 degrees extension.
  • There was no recurrence of a tumor or infection.
  • [MeSH-major] Arthrodesis. Bone Neoplasms / surgery. Fibula / transplantation. Giant Cell Tumor of Bone / surgery

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  • (PMID = 19672821.001).
  • [ISSN] 1098-8947
  • [Journal-full-title] Journal of reconstructive microsurgery
  • [ISO-abbreviation] J Reconstr Microsurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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77. Piedra MP, Scheithauer BW, Driscoll CL, Link MJ: Primary Melanocytic Tumor of the Cerebellopontine Angle Mimicking a Vestibular Schwannoma. Neurosurgery; 2006 Jul 01;59(1):E206
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  • [Title] Primary Melanocytic Tumor of the Cerebellopontine Angle Mimicking a Vestibular Schwannoma.

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  • (PMID = 28180621.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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78. Kim EM, Lee BS, Moon HS, Sung JK, Kim SH, Lee HY, Kang DY: Distal cholangiocarcinoma with gastric metastasis mimicking early gastric cancer. Gut Liver; 2009 Sep;3(3):222-5
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  • Computed tomography showed a malignant tumor of the common bile duct located just above the intrapancreatic segment, and endoscopy revealed a 2-cm, flat, elevated lesion with convergence of the surrounding folds, situated at the gastric angle.
  • Both tumors showed similar pathological features and were positive for cytokeratin (CK)-19 and CK-7.

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  • (PMID = 20431751.001).
  • [ISSN] 2005-1212
  • [Journal-full-title] Gut and liver
  • [ISO-abbreviation] Gut Liver
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2852712
  • [Keywords] NOTNLM ; Cholangiocarcinoma / Metastasis / Stomach
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79. Calabrese C, Pisi A, Di Febo G, Liguori G, Filippini G, Cervellera M, Righi V, Lucchi P, Mucci A, Schenetti L, Tonini V, Tosi MR, Tugnoli V: Biochemical alterations from normal mucosa to gastric cancer by ex vivo magnetic resonance spectroscopy. Cancer Epidemiol Biomarkers Prev; 2008 Jun;17(6):1386-95
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  • The aim of the present research was the application of ex vivo high-resolution magic angle spinning magnetic resonance spectroscopy (HR-MAS MRS) to the human gastric tissue to get information on the molecular steps involved in gastric carcinogenesis and the identification of biochemical markers useful for the development of in vivo MRS methodologies to diagnose gastric pathologies in clinical situations.
  • [MeSH-major] Adenocarcinoma / metabolism. Biomarkers, Tumor / metabolism. Gastric Mucosa / metabolism. Gastritis, Atrophic / metabolism. Helicobacter Infections / metabolism. Magnetic Resonance Spectroscopy / methods. Stomach Neoplasms / metabolism

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  • (PMID = 18559553.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Triglycerides; N91BDP6H0X / Choline; OF5P57N2ZX / Alanine; TE7660XO1C / Glycine
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81. Dukić W, Kuna T, Lapter-Varga M, Jurić H, Lulić-Dukić O: [Combined surgical-orthodontic therapy for compound odontoma]. Acta Med Croatica; 2007 Sep;61(4):405-9
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  • Odontogenic tumor is a rare condition in dental medicine that mostly proceeds unrecognized until the occurrence of clinical symptoms such as delayed eruption, or is incidentally detected on routine x-ray examination.
  • The exact cause is not known, however, previous dental trauma and infection have been postulated as the potential factors in the development of odontogenic tumor.
  • Orthodontic therapy is also of great importance in correct alignment of the teeth 'n the dental arch as well as in the management of other anomalies that may be associated with odontogenic tumor.
  • In this case, there was a massive odontogenic tumor which had compromised the growth of permanent teeth, and the growth impulse was almost at the end since the patient was 11 years old and the apexes of the upper incisors were partially closed.
  • [MeSH-major] Malocclusion, Angle Class I / therapy. Maxillary Neoplasms / surgery. Odontoma / surgery. Orthodontics, Corrective. Tooth, Unerupted / therapy

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  • (PMID = 18044477.001).
  • [ISSN] 1330-0164
  • [Journal-full-title] Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti
  • [ISO-abbreviation] Acta Med Croatica
  • [Language] hrv
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Croatia
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82. Cuthikonda B, Buckleair LJ, Goodman JC, Powell SZ, Rose JE: Ganglioglioma in the cerebellopontine angle of an adult without seizures. J La State Med Soc; 2009 May-Jun;161(3):143-6
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  • [Title] Ganglioglioma in the cerebellopontine angle of an adult without seizures.
  • We present a rare case of an adult patient without seizures who is found to have a ganglioglioma occurring in the cerebellopontine angle.
  • Magnetic resonance imaging (MRI) revealed a smooth, somewhat lobulated mass in the left cerebellopontine angle.
  • Ganglioglioma is a rare tumor of the central nervous system that typically presents with seizures in children and young adults.
  • Occurrence of this tumor in the cerebellopontine angle is extremely unusual; this rarity is magnified by its occurrence in an adult patient without a history of seizures.
  • Our case illustrates that ganglioglioma should be considered in the differential diagnosis of cerebellopontine angle masses at any age.
  • [MeSH-major] Brain Stem Neoplasms / diagnosis. Ganglioglioma / diagnosis
  • [MeSH-minor] Cerebellopontine Angle / pathology. Cerebellopontine Angle / surgery. Contrast Media. Female. Gadolinium. Humans. Magnetic Resonance Imaging / methods. Middle Aged. Neurosurgical Procedures

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  • (PMID = 19772036.001).
  • [ISSN] 0024-6921
  • [Journal-full-title] The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society
  • [ISO-abbreviation] J La State Med Soc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; AU0V1LM3JT / Gadolinium
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83. Kim KO, Kim JK, Kim SY: Optimized therapeutic neutron beam for accelerator-based BNCT by analyzing the neutron angular distribution from (7)Li(p,n)(7)Be reaction. Appl Radiat Isot; 2009 Jul-Aug;67(7-8):1173-9
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  • Perpendicular neutrons (i.e., solid angle bin of 50-150 degrees ) among ones generated from (7)Li(p,n)(7)Be reaction were used to produce an optimized therapeutic neutron beam for accelerator-based BNCT.
  • As a result of a simulation, it is found that a tumor at a depth of 60mm from the head skin could be treated within 5 minutes, if a typical tumor is assumed to be taken about 20RBEGy for therapeutic treatment.
  • It is, thus, expected that the neutrons emitted into the solid angle bin of 50-150 degrees from (7)Li(p,n)(7)Be reaction are very effective in producing epithermal neutron beams for BNCT.

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  • (PMID = 19303311.001).
  • [ISSN] 1872-9800
  • [Journal-full-title] Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
  • [ISO-abbreviation] Appl Radiat Isot
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 9FN79X2M3F / Lithium; OW5102UV6N / Beryllium
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84. Honda T, Makino N, Shirahata N, Tozawa T, Ikeda Y, So K, Matsuda A, Kato N, Motoyama T, Kawata S: [An autopsy case of periampullary carcinoid with amyloid stroma and type 1 neurofibromatosis]. Nihon Shokakibyo Gakkai Zasshi; 2009 Oct;106(10):1516-23
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  • CT showed a pancreatic head tumor 5 cm in diameter with calcification.
  • Esophagogastroduodenoscopy showed deformation and stenosis on the superior and inferior side of the duodenal angle due to a papillary tumor.
  • Thus, retrograde insertion of an endoscope was difficult, and a diagnosis of a carcinoid tumor was obtained by biopsy.
  • After disclosing the diagnosis to the patient, we explained the necessity of treatment.
  • The tumor was a carcinoid tumor with distant metastases which originated from the duodenal papillary area.
  • We report here a valuable case of carcinoid tumor with type 1 neurofibromatosis accompanied with amyloid deposits.
  • [MeSH-major] Ampulla of Vater. Amyloid / analysis. Carcinoid Tumor / complications. Common Bile Duct Neoplasms / complications. Neurofibromatosis 1 / complications

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  • (PMID = 19834300.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Amyloid
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85. Yang L, Li L, Tu Q, Ren L, Zhang Y, Wang X, Zhang Z, Liu W, Xin L, Wang J: Photocatalyzed surface modification of poly(dimethylsiloxane) with polysaccharides and assay of their protein adsorption and cytocompatibility. Anal Chem; 2010 Aug 1;82(15):6430-9
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  • Afterward, the amino-terminated PDMS substrates were sequentially reacted with CMC, CMD, and AA in the presence of N-hydroxysuccinimide and 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide, resulting in the grafting of polysaccharides onto PDMS surfaces.
  • In addition, the stability and dynamic characteristics of the polysaccharide-grafted PDMS substrates were investigated by XPS and temporal contact angle experiments.
  • [MeSH-minor] Adsorption. Alginates / chemistry. Animals. Carboxymethylcellulose Sodium / chemistry. Cattle. Cell Line, Tumor. Glucuronic Acid / chemistry. Hexuronic Acids / chemistry. Humans. Methacrylates / chemistry. Muramidase / chemistry. Organosilicon Compounds / chemistry. Ribonuclease, Pancreatic / chemistry. Serum Albumin, Bovine / chemistry. Surface Properties. beta-Cyclodextrins / chemistry

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  • (PMID = 20614927.001).
  • [ISSN] 1520-6882
  • [Journal-full-title] Analytical chemistry
  • [ISO-abbreviation] Anal. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Alginates; 0 / Dimethylpolysiloxanes; 0 / Hexuronic Acids; 0 / Methacrylates; 0 / Organosilicon Compounds; 0 / Polysaccharides; 0 / Proteins; 0 / Serum Albumin, Bovine; 0 / beta-Cyclodextrins; 0 / carboxymethyl-beta-cyclodextrin; 63148-62-9 / baysilon; 8A5D83Q4RW / Glucuronic Acid; 8C3Z4148WZ / alginic acid; 9004-32-4 / Carboxymethylcellulose Sodium; EC 3.1.27.5 / Ribonuclease, Pancreatic; EC 3.2.1.17 / Muramidase; JV48X1M2EQ / 3-(trimethoxysilyl)propyl methacrylate
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86. Ueda T, Andreas C, Itami J, Miyakawa K, Fujimoto H, Ito H, Roos JE: Pyothorax-associated lymphoma: imaging findings. AJR Am J Roentgenol; 2010 Jan;194(1):76-84
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  • Masses of pyothorax-associated lymphoma were commonly located in the lateral costal pleura (50%) or at the costophrenic angle (30%).
  • The tumor matrix often appeared heterogeneous and contained areas of necrosis (60%).
  • Knowledge of the typical radiologic findings and locations of pyothorax-associated lymphoma help in the diagnosis of this rare pathologic entity.
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Female. Gallium Radioisotopes. Humans. Japan. Male. Middle Aged. Radiography, Thoracic. Retrospective Studies. Tomography, Emission-Computed. Tuberculosis, Pleural / complications. Whole Body Imaging

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  • (PMID = 20028908.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gallium Radioisotopes
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87. Koch HJ, Roeber S, Zimmermann UW, Schäfer C, Villarrubia V, Kuchelmeister K, Schachenmayr W, Bogdahn U, Steinbrecher A: [Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle]. Wien Med Wochenschr; 2005 Aug;155(15-16):360-4
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  • [Title] [Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle].
  • [Transliterated title] Spinale und zerebrale Meningeosis eines sekundär malignisierten Melanozytoms des Kleinhirnbrückenwinkels.
  • Meningeal melanocytoma refers to the uncommon clinical appearance of a generally benign tumour deriving from leptomeningeal melanocytes.
  • Meningeal spread of this tumour is very rarely observed.
  • We present the case of a 38-year-old man with meningeal melanocytoma of the cerebello-pontine angle, who showed a biphasic course of this disease, with a stable period followed by a steady progress within few months.
  • After surgical resection of the melancytoma in the left skull base and of a first local recurrence five years later, a second local recurrence occurred 6 years after diagnosis, with intracerebral and spinal meningeal seeding.
  • This tumor did not respond to a combined radiochemotherapy including oral temozolomide, and the patient died 5 months after starting treatment for this relapse.
  • [MeSH-major] Cerebellopontine Angle. Melanocytes / pathology. Melanoma. Meningeal Neoplasms. Meninges. Neoplasm Seeding
  • [MeSH-minor] Administration, Oral. Adult. Antineoplastic Agents, Alkylating / administration & dosage. Antineoplastic Agents, Alkylating / therapeutic use. Arachnoid. Cerebellar Diseases / diagnosis. Cerebellar Neoplasms / diagnosis. Combined Modality Therapy. Dacarbazine / analogs & derivatives. Dacarbazine / therapeutic use. Diagnosis, Differential. Disease Progression. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local. Pia Mater. Radiotherapy Dosage. Time Factors

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  • (PMID = 16160923.001).
  • [ISSN] 0043-5341
  • [Journal-full-title] Wiener medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Wien Med Wochenschr
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide
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88. dos Santos Rubio EJ, Harhangi BS, Kros JM, Vincent AJ, Dirven CM: A primary extraosseous Ewing sarcoma in the cerebellopontine angle of a child: review of relevant literature and case report. Neurosurgery; 2010 Dec;67(6):E1852-6
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  • [Title] A primary extraosseous Ewing sarcoma in the cerebellopontine angle of a child: review of relevant literature and case report.
  • BACKGROUND AND IMPORTANCE: We report the occurrence of a primary intracranial extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumor (EES/pPNET) in the cerebellopontine angle in a child.
  • Tumor cells displayed membranous expression of CD99, and one of the typical translocations of EES/pPNET (chromosome 22) was demonstrated by cytogenetic analysis.
  • Although exceptionally rare, intracranial EES/pPNET should be considered in the differential diagnosis of lesions in the cerebellopontine angle.
  • [MeSH-major] Bone Neoplasms / complications. Cerebellar Neoplasms / complications. Cerebellopontine Angle / pathology. Sarcoma, Ewing / complications

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  • (PMID = 21107154.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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89. Shin IH, Shin SM, Kim DY: New, simple theory-based, accurate polarization microscope for birefringence imaging of biological cells. J Biomed Opt; 2010 Jan-Feb;15(1):016028
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  • The orientation of the principal axis is calculated from the angle of the polarizer for the intensity maximum.
  • [MeSH-minor] Breast Neoplasms / pathology. Cell Line, Tumor. Female. Humans

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  • (PMID = 20210472.001).
  • [ISSN] 1560-2281
  • [Journal-full-title] Journal of biomedical optics
  • [ISO-abbreviation] J Biomed Opt
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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90. Wright AJ, Fellows GA, Griffiths JR, Wilson M, Bell BA, Howe FA: Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers. Mol Cancer; 2010 Mar 23;9:66
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  • [Title] Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers.
  • BACKGROUND: High-resolution magic angle spinning (HRMAS) NMR spectroscopy allows detailed metabolic analysis of whole biopsy samples for investigating tumour biology and tumour classification.
  • Accurate biochemical assignment of small molecule metabolites that are "NMR visible" will improve our interpretation of HRMAS data and the translation of NMR tumour biomarkers to in-vivo studies.
  • RESULTS: 1D and 2D 1H HRMAS NMR was used to determine that 29 small molecule metabolites, along with 8 macromolecule signals, account for the majority of the HRMAS spectrum of the main types of brain tumour (astrocytoma grade II, grade III gliomas, glioblastomas, metastases, meningiomas and also lymphomas).
  • Differences in concentration of 20 of these metabolites were statistically significant between these brain tumour types.
  • CONCLUSIONS: A number of small molecule metabolites have been identified as potential biomarkers of tumour type that may enable development of more selective in-vivo 1H NMR acquisition methods for diagnosis and prognosis of brain tumours.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Brain Neoplasms / metabolism. Magnetic Resonance Spectroscopy / methods

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  • (PMID = 20331867.001).
  • [ISSN] 1476-4598
  • [Journal-full-title] Molecular cancer
  • [ISO-abbreviation] Mol. Cancer
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0601327
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2858738
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91. Jiang WH, Zhao SP, Xie ZH, Zhang H, Huang DH, Cai XZ, Zhang JY, Xiao JY: [A preliminary study of endoscopic transoral trans-posteriorwall pharynx resection of hypo-clivus chordoma]. Zhonghua Yi Xue Za Zhi; 2007 Jul 24;87(28):2007-10
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  • RESULTS: The MR image showed that total removal of the tumor was achieved in 2 patients and subtotal resection was received in one patient.
  • In 6 months to 2 years' follow-up, the MRI showed that 2 patients had no residue tumor, and one patient died due to recurrence of the tumor 1 year after operation.
  • Especially, various angle view of the endoscope provides a panoramic view of the hypo-clivus, thus exposing and resecting hide lesion which can not be exposed by other approaches.

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  • (PMID = 17923047.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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92. Mandl ES, Vandertop WP, Meijer OW, Peerdeman SM: Imaging-documented repeated intratumoral hemorrhage in vestibular schwannoma: a case report. Acta Neurochir (Wien); 2009 Oct;151(10):1325-7
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  • Intratumoral hemorrhage is probably caused by vascular fragility associated with tumor characteristics and growth.
  • [MeSH-major] Cerebellopontine Angle / pathology. Intracranial Hemorrhages / diagnosis. Intracranial Hemorrhages / etiology. Neuroma, Acoustic / complications. Neuroma, Acoustic / diagnosis. Vestibular Nerve / pathology

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  • (PMID = 19255715.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Other-IDs] NLM/ PMC2760714
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93. Ahmed I, Auguste KI, Vachhrajani S, Dirks PB, Drake JM, Rutka JT: Neurosurgical management of intracranial epidermoid tumors in children. Clinical article. J Neurosurg Pediatr; 2009 Aug;4(2):91-6
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  • [Title] Neurosurgical management of intracranial epidermoid tumors in children. Clinical article.
  • OBJECT: Epidermoid tumors are benign lesions representing 1% of all intracranial tumors.
  • There have been few pediatric series of intracranial epidermoid tumors reported previously.
  • METHODS: The neurosurgical database at the Hospital for Sick Children was searched for children with surgically managed intracranial epidermoid tumors.
  • The average age at surgery was 11.2 years (range 8-15 years), and the mean maximal tumor diameter was 2.1 cm.
  • Headache was the most common presenting symptom, and 1 tumor was found incidentally.
  • There were 3 cerebellopontine angle lesions, 1 pontomedullary lesion, and 3 supratentorial tumors.
  • CONCLUSIONS: Intracranial epidermoid tumors are rare in the pediatric population.
  • Total resection is desirable to minimize the risk of postoperative aseptic meningitis, hydrocephalus, and tumor recurrence.
  • [MeSH-major] Brain Diseases / diagnosis. Brain Diseases / surgery. Craniotomy. Epidermal Cyst / diagnosis. Epidermal Cyst / surgery. Neuronavigation

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  • (PMID = 19645539.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Haacke EM, Filleti CL, Gattu R, Ciulla C, Al-Bashir A, Suryanarayanan K, Li M, Latif Z, DelProposto Z, Sehgal V, Li T, Torquato V, Kanaparti R, Jiang J, Neelavalli J: New algorithm for quantifying vascular changes in dynamic contrast-enhanced MRI independent of absolute T1 values. Magn Reson Med; 2007 Sep;58(3):463-72
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  • In this work, we present a new method for predicting changes in tumor vascularity using only one flip angle in dynamic contrast-enhanced (DCE) imaging.
  • Consequently, the NR50 for the tumor remains roughly the same as the ideal NR50 when T1(0) is exactly known.

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  • [Copyright] Copyright (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17763352.001).
  • [ISSN] 0740-3194
  • [Journal-full-title] Magnetic resonance in medicine
  • [ISO-abbreviation] Magn Reson Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Central Nervous System Stimulants; 0 / Contrast Media; 3G6A5W338E / Caffeine; K2I13DR72L / Gadolinium DTPA
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95. Harris MS, Harris GJ, Simons KB, Campbell BH: Massive extraocular extension and parotid lymph node metastasis of uveal melanoma. Ophthal Plast Reconstr Surg; 2007 Sep-Oct;23(5):430-2
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  • MRI displayed intra- and extraocular tumor, and gross invasion of the medial rectus muscle.
  • The tumor infiltrated superficial parotid nodes and extended into the parotid gland.
  • The site of tumor origin is speculative, but a ring melanoma of the anterior chamber angle is suspected.

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  • (PMID = 17882007.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY01931
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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96. Saglar E, Yucel D, Bozkurt B, Ozgul RK, Irkec M, Ogus A: Association of polymorphisms in APOE, p53, and p21 with primary open-angle glaucoma in Turkish patients. Mol Vis; 2009;15:1270-6
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  • [Title] Association of polymorphisms in APOE, p53, and p21 with primary open-angle glaucoma in Turkish patients.
  • PURPOSE: To investigate the association between Apolipoprotein E (APOE), tumor suppressor protein p53 (p53), and cyclin-dependent kinase inhibitor 1A (p21) genes and primary open-angle glaucoma (POAG) in a cohort of Turkish subjects.
  • [MeSH-major] Apolipoproteins E / genetics. Cyclin-Dependent Kinase Inhibitor p21 / genetics. Genes, p53. Glaucoma, Open-Angle / genetics. Polymorphism, Genetic


97. Fleming ES, Zajac M, Moschenross DM, Montrose DC, Rosenberg DW, Cowan AE, Tirnauer JS: Planar spindle orientation and asymmetric cytokinesis in the mouse small intestine. J Histochem Cytochem; 2007 Nov;55(11):1173-80
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  • Spindle angle relative to the apical cell surface was determined either by direct measurement from confocal images or with a computational algorithm.
  • Angles averaged within 10 degrees of parallel to the apical surface in metaphase and anaphase cells, consistent with robust planar spindle positioning, whereas spindles in prometaphase cells showed much greater angle variability.
  • This type of image analysis may be useful for studying the regulation of spindle position during tissue remodeling and tumor formation.

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  • (PMID = 17712178.001).
  • [ISSN] 0022-1554
  • [Journal-full-title] The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • [ISO-abbreviation] J. Histochem. Cytochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tubulin
  • [Other-IDs] NLM/ PMC3957531
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98. Bennett ML, Jackson CG, Kaufmann R, Warren F: Postoperative imaging of vestibular schwannomas. Otolaryngol Head Neck Surg; 2008 May;138(5):667-71
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  • Analysis of tumor recurrence and correlation with enhancement types on postoperative imaging was performed.
  • RESULTS: During the five-year period, 359 cerebellopontine angle tumors were removed.
  • Two patients with nodular enhancement had tumor recurrence.
  • [MeSH-major] Magnetic Resonance Imaging. Neuroma, Acoustic / diagnosis. Neuroma, Acoustic / surgery. Postoperative Care

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  • (PMID = 18439476.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. McGirt MJ, Chaichana KL, Atiba A, Bydon A, Witham TF, Yao KC, Jallo GI: Incidence of spinal deformity after resection of intramedullary spinal cord tumors in children who underwent laminectomy compared with laminoplasty. J Neurosurg Pediatr; 2008 Jan;1(1):57-62
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  • [Title] Incidence of spinal deformity after resection of intramedullary spinal cord tumors in children who underwent laminectomy compared with laminoplasty.
  • OBJECT: Gross-total resection of pediatric intramedullary spinal cord tumor (IMSCT) can be achieved in the majority of cases while preserving long-term neurological function.
  • The next 20 consecutive patients presenting for resection of IMSCTs underwent osteoplastic laminotomy regardless of patient or tumor characteristics.
  • There were no differences (p > 0.10) between patients treated with osteoplastic laminotomy and those treated with laminectomy in terms of the following characteristics: age; sex; duration of symptoms; location of tumor; incidence of preoperative scoliosis (Cobb angle > 10 degrees : 7 [35%] with laminoplasty compared with 49 [34%] with laminectomy); involvement of the cervicothoracic junction (7 [35%] compared with 57 [40%]); thoracolumbar junction (4 [20%] compared with 36 [25%]); tumor size; extent of resection; radiation therapy; histopathological findings; or mean operative spinal levels (7.5 +/- 2 compared with 7.5 +/- 3).

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  • (PMID = 18352804.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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100. Schefler AC, Mutapcic L, Murray TG, Dubovy SR: Optic nerve invasion from an amelanotic peripapillary choroidal melanoma. Retin Cases Brief Rep; 2009;3(4):329-32
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  • The patient did have a history of primary open angle glaucoma, which may have rendered the optic nerve more susceptible to tumor invasion.

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  • (PMID = 25389839.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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