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51. Manner J, Radlwimmer B, Hohenberger P, Mössinger K, Küffer S, Sauer C, Belharazem D, Zettl A, Coindre JM, Hallermann C, Hartmann JT, Katenkamp D, Katenkamp K, Schöffski P, Sciot R, Wozniak A, Lichter P, Marx A, Ströbel P: MYC high level gene amplification is a distinctive feature of angiosarcomas after irradiation or chronic lymphedema. Am J Pathol; 2010 Jan;176(1):34-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MYC high level gene amplification is a distinctive feature of angiosarcomas after irradiation or chronic lymphedema.
  • Angiosarcomas (AS) are rare vascular malignancies that arise either de novo as primary tumors or secondary to irradiation or chronic lymphedema.
  • The cytogenetics of angiosarcomas are poorly characterized.
  • Fluorescence in situ hybridization analysis in 28 primary and 33 secondary angiosarcomas (31 tumors secondary to irradiation, 2 tumors secondary to chronic lymphedema) confirmed high level amplification of MYC on chromosome 8q24.21 as a recurrent genetic alteration found exclusively in 55% of AS secondary to irradiation or chronic lymphedema, but not in primary AS.
  • This finding may have implications both for the diagnosis and treatment of these tumors.
  • [MeSH-major] Gene Amplification / genetics. Hemangiosarcoma / etiology. Hemangiosarcoma / genetics. Lymphedema / complications. Proto-Oncogene Proteins c-myc / genetics. Radiotherapy / adverse effects
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chromosome Deletion. Chronic Disease. DNA Copy Number Variations / genetics. Female. Genetic Loci / genetics. Homozygote. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged

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  • (PMID = 20008140.001).
  • [ISSN] 1525-2191
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins c-myc
  • [Other-IDs] NLM/ PMC2797867
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52. Bioulac-Sage P, Laumonier H, Laurent C, Blanc JF, Balabaud C: Benign and malignant vascular tumors of the liver in adults. Semin Liver Dis; 2008 Aug;28(3):302-14
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  • [Title] Benign and malignant vascular tumors of the liver in adults.
  • Vascular tumors of the liver in adult patients include cavernous hemangioma, a common benign tumor; epithelioid hemangioendothelioma, a rare, usually low-grade malignant tumor; and angiosarcoma, a rare and very aggressive tumor.
  • A definitive diagnosis of epithelioid hemangioendothelioma and angiosarcoma requires histopathologic examination.
  • Liver transplantation at an early stage has greatly improved the prognosis of epithelioid hemangioendothelioma.
  • The prognosis of angiosarcoma remains dismal.
  • [MeSH-minor] Adult. Hemangioendothelioma, Epithelioid / pathology. Hemangioendothelioma, Epithelioid / therapy. Hemangioma, Cavernous / pathology. Hemangioma, Cavernous / therapy. Hemangiosarcoma / pathology. Hemangiosarcoma / therapy. Hepatic Stellate Cells / pathology. Humans. Sarcoma, Kaposi / pathology. Sarcoma, Kaposi / therapy. Treatment Outcome

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  • (PMID = 18814083.001).
  • [ISSN] 0272-8087
  • [Journal-full-title] Seminars in liver disease
  • [ISO-abbreviation] Semin. Liver Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 45
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53. Christensen N, Canfield P, Martin P, Krockenberger M, Spielman D, Bosward K: Cytopathological and histopathological diagnosis of canine splenic disorders. Aust Vet J; 2009 May;87(5):175-81
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  • [Title] Cytopathological and histopathological diagnosis of canine splenic disorders.
  • OBJECTIVES: To determine (1) the common types of canine splenic disorders, and the breeds affected, that are diagnosed by cytopathological and histopathological examination in Sydney, Australia and (2) the accuracy of cytopathological examination compared with histopathological examination for the diagnosis of canine splenic disorders.
  • RESULTS: The most common cytopathological diagnoses were benign disorders of growth, vascular disturbances and necrosis (29%), followed by no abnormalities detectable (28%), malignant neoplasms (20%), equivocal diagnoses (20%) and inflammatory disorders (3%).
  • The most common histopathological diagnoses were benign disorders of growth, vascular disturbances and necrosis (49%), followed by malignant neoplasms (43%) and inflammatory disorders (8%).
  • German Shepherd Dogs were the most common breed diagnosed histopathologically with haemangiosarcoma.
  • Although cytopathological and histopathological splenic examinations are complementary for diagnosis, this study has shown a high correlation for complete and partial agreement between the two.

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  • (PMID = 19382924.001).
  • [ISSN] 0005-0423
  • [Journal-full-title] Australian veterinary journal
  • [ISO-abbreviation] Aust. Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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5
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4. Liu ZH, Lee ST, Jung SM, Tu PH: Primary spinal angiosarcoma. J Clin Neurosci; 2010 Mar;17(3):387-9
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  • [Title] Primary spinal angiosarcoma.
  • Primary angiosarcoma of the spine is rare.
  • To our knowledge, primary angiosarcoma in the posterior element of the spine has not been reported previously.
  • [MeSH-major] Hemangiosarcoma. Spinal Neoplasms

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  • [Copyright] Copyright 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 20074966.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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55. Bonaccorsi-Riani E, Lerut JP: Liver transplantation and vascular tumours. Transpl Int; 2010 Jul;23(7):686-91
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  • Hepatic epithelioid haemangioendothelioma has currently become a good indication for LT with 5- and 10-year post-LT patient survival rates of 83% and 74% respectively and 5- and 10-year recurrence-free survival rates of 82% and 64% respectively.
  • In contrast, the results of LT for haemangiosarcoma (HAS) are disastrous with an universal tumour recurrence within 6 months and no single patient survival after 2 years.
  • The value of LT in the treatment of infantile haemangioendothelioma is more difficult to evaluate because of the very reduced number of reported cases and because of the often difficult differential diagnosis with angiosarcoma.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / surgery. Hemangiosarcoma / surgery. Liver Neoplasms / surgery. Liver Transplantation. Vascular Neoplasms / surgery

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  • (PMID = 20492619.001).
  • [ISSN] 1432-2277
  • [Journal-full-title] Transplant international : official journal of the European Society for Organ Transplantation
  • [ISO-abbreviation] Transpl. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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56. Meyers RL: Tumors of the liver in children. Surg Oncol; 2007 Nov;16(3):195-203
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  • In this review we examine the diagnosis and treatment of pediatric liver tumors- both malignant and benign.
  • The two most common malignant tumors are hepatoblastoma and hepatocellular carcinoma.
  • Other malignant liver tumors are quite rare and include biliary rhabdomyosarcoma, angiosarcoma, rhabdoid tumor, and undifferentiated sarcoma.

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  • (PMID = 17714939.001).
  • [ISSN] 0960-7404
  • [Journal-full-title] Surgical oncology
  • [ISO-abbreviation] Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 69
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57. Lim RF, Goei R: Best cases from the AFIP: angiosarcoma of the breast. Radiographics; 2007 Oct;27 Suppl 1:S125-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Best cases from the AFIP: angiosarcoma of the breast.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology

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  • (PMID = 18180222.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Poellinger A, Landt S, Diekmann F, Guski H, Bick U: Rapid growth of an exophytic angiosarcoma of the breast. Breast J; 2006 Jan-Feb;12(1):80-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rapid growth of an exophytic angiosarcoma of the breast.
  • [MeSH-major] Breast Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Ductal, Breast / diagnosis. Carcinoma, Ductal, Breast / pathology. Carcinoma, Ductal, Breast / radiography. Carcinoma, Ductal, Breast / surgery. Diagnosis, Differential. Female. Humans. Mammography. Mastectomy

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  • (PMID = 16409594.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. Sorenmo K, Samluk M, Clifford C, Baez J, Barrett JS, Poppenga R, Overley B, Skorupski K, Oberthaler K, Van Winkle T, Seiler G, Shofer F: Clinical and pharmacokinetic characteristics of intracavitary administration of pegylated liposomal encapsulated doxorubicin in dogs with splenic hemangiosarcoma. J Vet Intern Med; 2007 Nov-Dec;21(6):1347-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical and pharmacokinetic characteristics of intracavitary administration of pegylated liposomal encapsulated doxorubicin in dogs with splenic hemangiosarcoma.
  • BACKGROUND: Canine splenic hemangiosarcoma (HSA) is a fatal malignancy, and most affected dogs die within a few months of diagnosis.
  • The abdomen is also the main site of disease recurrence.
  • After staging of disease status and splenectomy, pegylated liposomal encapsulated doxorubicin was administered intraperitoneally (1 mg/kg body weight) every 3 weeks for 4 cycles.

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  • (PMID = 18196746.001).
  • [ISSN] 0891-6640
  • [Journal-full-title] Journal of veterinary internal medicine
  • [ISO-abbreviation] J. Vet. Intern. Med.
  • [Language] ENG
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / liposomal doxorubicin; 30IQX730WE / Polyethylene Glycols; 80168379AG / Doxorubicin
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60. Umscheid TW, Rouhani G, Morlang T, Lorey T, Klein PJ, Ziegler P, Stelter WJ: Hemangiosarcoma after endovascular aortic aneurysm repair. J Endovasc Ther; 2007 Feb;14(1):101-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemangiosarcoma after endovascular aortic aneurysm repair.
  • PURPOSE: To report a rare case of hemangiosarcoma after endovascular aneurysm repair (EVAR).
  • CONCLUSION: Morphological changes of the aneurysm wall seen on computed tomographic scans of EVAR patients may not be incidental or signs of infection; rather, a malignant tumor of the aorta or lymphatic disease, although rare, have to be taken into consideration as well.
  • [MeSH-major] Aortic Aneurysm, Abdominal / surgery. Blood Vessel Prosthesis Implantation / adverse effects. Hemangiosarcoma / etiology. Stents

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  • (PMID = 17291154.001).
  • [ISSN] 1526-6028
  • [Journal-full-title] Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
  • [ISO-abbreviation] J. Endovasc. Ther.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Polyethylene Terephthalates
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61. Choi KS, Chun HJ, Yi HJ, Kim JT: Intracranial invasion from recurrent angiosarcoma of the scalp. J Korean Neurosurg Soc; 2008 Apr;43(4):201-4
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  • [Title] Intracranial invasion from recurrent angiosarcoma of the scalp.
  • Angiosarcoma of the brain, either primary or metastatic is extremely rare.
  • Moreover, angiosarcoma metastasizing to the brain is also highly unlike to occur comparing with metastases to the other organs.
  • A 67-year-old man with past surgical history of a scalp angiosarcoma underwent surgical resection of intracranial invasion.

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  • (PMID = 19096645.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588263
  • [Keywords] NOTNLM ; Brain neoplasm / Metastasis / Scalp Angiosarcoma / Scalp flap
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62. Berry MF, Williams M, Welsby I, Lin S: Cardiac angiosarcoma presenting with right coronary artery pseudoaneurysm. J Cardiothorac Vasc Anesth; 2010 Aug;24(4):633-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac angiosarcoma presenting with right coronary artery pseudoaneurysm.
  • [MeSH-major] Aneurysm, False / diagnosis. Coronary Vessels / pathology. Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male

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  • (PMID = 19525126.001).
  • [ISSN] 1532-8422
  • [Journal-full-title] Journal of cardiothoracic and vascular anesthesia
  • [ISO-abbreviation] J. Cardiothorac. Vasc. Anesth.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Sluzevich JC, Gloster HJ, Mutasim DF: A case of regressing central facial cutaneous angiosarcoma. J Am Acad Dermatol; 2008 May;58(5 Suppl 1):S113-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of regressing central facial cutaneous angiosarcoma.
  • [MeSH-major] Eyelid Neoplasms / pathology. Hemangiosarcoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 18489041.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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64. van Geel AN, den Bakker MA: Bilateral angiosarcoma of the breast in a fourteen-year-old child. Rare Tumors; 2009;1(2):e38
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral angiosarcoma of the breast in a fourteen-year-old child.
  • Malignant vascular tumors are rare and angiosarcomas of the breast in patients under 21 years of age are exceedingly uncommon.
  • In this report an angiosarcoma in the breast of a 14-year-old girl is described.
  • She died nine months after mastectomy with recurrent disease in the bones and the contralateral breast.
  • The etiology of most primary angiosarcomas is unknown.
  • Secondary angiosarcomas can develop after radiotherapy and chronic lymphedema.
  • The histology of this angiosarcoma is illustrated.

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  • (PMID = 21139917.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994455
  • [Keywords] NOTNLM ; angiosarcoma / breast. / infancy
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65. Holloway CL, Turner AR, Dundas GS: Cutaneous angiosarcoma of the scalp: a case report of sustained complete response following liposomal Doxorubicin and radiation therapy. Sarcoma; 2005;9(1-2):29-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous angiosarcoma of the scalp: a case report of sustained complete response following liposomal Doxorubicin and radiation therapy.
  • Cutaneous angiosarcomas of the head and neck are aggressive cancers with a mean overall survival of 30 months.
  • We add to the literature a case report of a 65-year-old man with a large, >10 cm, unresectable, angiosarcoma of the scalp who was treated with two cycles of liposomal doxorubicin (Caelyx(R)) followed by electron beam radiation therapy (30 Gy in 10 fractions over 2 weeks) who has sustained a complete response with a 4-year follow-up.

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  • (PMID = 18521414.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2395620
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66. Jin M, Matsumoto S, Dewa Y, Nishimura J, Saekusa Y, Hasumi K, Mitsumori K: Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane. Arch Toxicol; 2008 Oct;82(10):771-7
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  • [Title] Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane.
  • To examine the tumor-promoting effect of troglitazone (TRG), a novel thiazolidinedione insulin-sensitizing agent, on splenic hemangiosarcomas in rasH2 mice, histopathological and molecular analyses were performed in the spleen of female rasH2 mice fed a diet containing 6,000 or 0 ppm TRG for 16 weeks after 1,000 or 0 mg/kg urethane (UR) initiation.
  • Histopathologically, splenic hemangiosarcomas were observed in the UR-alone and UR + TRG groups, but there was no significant difference in the incidence of splenic hemangiosarcomas between the UR-alone and UR+TRG groups.
  • These results suggest that the vascular tumor-promoting activity of TRG in rasH2 mice is extremely low in the present experimental condition and a part of the gene related to angiogenesis probably contributes to the promotion of splenic hemangiosarcomas in rasH2 mice given TRG.
  • [MeSH-major] Carcinogens / toxicity. Chromans / toxicity. Hemangiosarcoma / chemically induced. Neoplasms, Experimental / chemically induced. Proto-Oncogene Proteins p21(ras) / genetics. Splenic Neoplasms / chemically induced. Thiazolidinediones / toxicity

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  • (PMID = 18465119.001).
  • [ISSN] 1432-0738
  • [Journal-full-title] Archives of toxicology
  • [ISO-abbreviation] Arch. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Angiogenic Proteins; 0 / Carcinogens; 0 / Chromans; 0 / Thiazolidinediones; 3IN71E75Z5 / Urethane; EC 3.6.5.2 / HRAS protein, human; EC 3.6.5.2 / Proto-Oncogene Proteins p21(ras); I66ZZ0ZN0E / troglitazone
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67. Dunlap JB, Magenis RE, Davis C, Himoe E, Mansoor A: Cytogenetic analysis of a primary bone angiosarcoma. Cancer Genet Cytogenet; 2009 Oct;194(1):1-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytogenetic analysis of a primary bone angiosarcoma.
  • Primary bone angiosarcomas are rare and aggressive vascular malignancies with a high mortality rate.
  • To our knowledge, there are no reported cytogenetic abnormalities in primary bone angiosarcomas, although several have been reported in soft tissue angiosarcomas.
  • We report a case of primary bone angiosarcoma, arising in the tibia of a 79-year-old woman, with a unique clonal chromosomal rearrangement: t(1;14)(p21;q24), that has not been reported in either soft tissue or primary bone angiosarcoma.
  • [MeSH-major] Bone Neoplasms / genetics. Hemangiosarcoma / genetics. Translocation, Genetic

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  • (PMID = 19737647.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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68. Korkolis DP, Papaevangelou M, Koulaxouzidis G, Zirganos N, Psichogiou H, Vassilopoulos PP: Intravascular papillary endothelial hyperplasia (Masson's hemangioma) presenting as a soft-tissue sarcoma. Anticancer Res; 2005 Mar-Apr;25(2B):1409-12
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  • [Title] Intravascular papillary endothelial hyperplasia (Masson's hemangioma) presenting as a soft-tissue sarcoma.
  • Intravascular papillary endothelial hyperplasia (Masson's hemangioma) is an unusual benign, non-neoplastic, vascular lesion characterized histologically by papillary fronds lined by proliferating endothelium.
  • The main significance of intravascular papillary endothelial hyperplasia is its clinical and histological resemblance to soft-tissue sarcoma and possible misinterpretation as such.
  • A case of intravascular papillary endothelial hyperplasia clinically diagnosed and treated as a low-grade angiosarcoma, in a 60-year-old man, presenting with a mass in the left thigh, is reported.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Thigh
  • [MeSH-minor] Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Sarcoma / diagnosis. Soft Tissue Neoplasms / diagnosis


69. Heo SH, Jeong YY, Shin SS, Chung TW, Kang HK: Solitary small hepatic angiosarcoma: initial and follow-up imaging findings. Korean J Radiol; 2007 Mar-Apr;8(2):180-3
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  • [Title] Solitary small hepatic angiosarcoma: initial and follow-up imaging findings.
  • We report an uncommon case of solitary, small hepatic angiosarcoma that was initially considered as a hemangioma.
  • We present the imaging findings, with an emphasis on the initial and follow-up CT and MR findings, as well as report on the more suggestive findings of angiosarcoma than those of a hemangioma.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Contrast Media. Diagnosis, Differential. Gadolinium DTPA. Hemangioma / diagnosis. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

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  • [Cites] AJR Am J Roentgenol. 2000 Jul;175(1):165-70 [10882268.001]
  • [Cites] Hepatogastroenterology. 2000 Nov-Dec;47(36):1717-8 [11149040.001]
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  • (PMID = 17420638.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
  • [Other-IDs] NLM/ PMC2626776
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70. Welsh SJ, Khan S: Radiological localizing techniques in adrenal tumors. Minerva Endocrinol; 2009 Jun;34(2):161-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Unfortunately, there may be significant overlap between the imaging appearances of benign lesions such as lipid-poor adenomas and malignant lesions, particularly metastases and small adrenal carcinomas.
  • This review highlights recent advances in radiological imaging of adrenal lesions and we discuss the relative merits of CT and magnetic resonance imaging to aid the identification of benign and malignant adrenal lesions and their roles, in combination with biochemical and clinical data, in recognizing common pathologies such as adrenal adenoma, phaeochromocytoma, carcinoma and metastases.
  • We also discuss the radiological characteristics of rarer adrenal lesions including lymphoma, neuroblastic tumours (neuroblastoma, ganglioneuroblastoma, and ganglioneuroma), lipomatous tumours (myelolipoma, angiolipoma, teratoma, lipoma and liposarcoma), in addition to hemangioma, hemangiosarcoma and leiomyosarcoma.
  • [MeSH-minor] Adrenal Cortex Neoplasms / radiography. Adrenocortical Adenoma / radiography. Adrenocortical Carcinoma / radiography. Diagnosis, Differential. Ganglioneuroblastoma / radiography. Ganglioneuroma / radiography. Humans. Lymphoma / radiography. Magnetic Resonance Imaging. Neoplasm Metastasis. Neoplasms, Adipose Tissue / radiography. Neoplasms, Vascular Tissue / radiography. Neuroblastoma / radiography. Pheochromocytoma / radiography. Predictive Value of Tests. Sensitivity and Specificity. Teratoma / radiography

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  • (PMID = 19471240.001).
  • [ISSN] 0391-1977
  • [Journal-full-title] Minerva endocrinologica
  • [ISO-abbreviation] Minerva Endocrinol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 42
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71. Lincoln DT, Singal PK, Al-Banaw A: Growth hormone in vascular pathology: neovascularization and expression of receptors is associated with cellular proliferation. Anticancer Res; 2007 Nov-Dec;27(6B):4201-18
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  • The well-differentiated tumours consist of irregular anastomosing, blood-filled vascular channels that are lined by variably atypical endothelial cells.
  • Several growth factors, including basic fibroblast growth factor, transforming growth factors and vascular endothelial growth factor, play a role in tumour angiogenesis.
  • Growth hormone (GH) is mitogenic for a variety of vascular tissue cells, including smooth muscle cells, fibroblasts and endothelial cells and exerts its regulatory functions in controlling metabolism, balanced growth and differentiated cell expression by acting on specific membrane-bound receptors, which trigger a phosphorylation cascade resulting in the modulation of numerous signalling pathways and of gene expression.
  • A total of 64 benign and malignant vascular tumours were obtained from different human organ sites, including the chest wall, skin, axillary contents, duodenum, female breast, abdomen, stomach, colon, lymph node, bladder, body flank and neck regions.
  • The tumours were of the following pathological entities: Haemangioma (n = 12); haemangioendothelioma (n = 10); Castleman's disease (n = 3), haemangiopericytoma (n = 4); angiosarcoma, (n = 11), Kaposi's sarcoma with focal infiltration by lymphoma, HIV +ve (n = 7), Kaposi's sarcoma (n = 17).
  • The endothelial cell marker CD-31 was used to establish endothelial cell characteristics and microvascular density.
  • Results show that, compared to their normal tissue counterparts, nuclear and cytoplasmic expression of GHR consistently result in strong receptor immunoreactivity in the highly malignant angiosarcomas and Kaposi's sarcomas and was localized in the cell membranes and cytoplasm, but strong nuclear immunoreactivity was also identified.
  • Malignant cells, which are highly expressive of the receptor, have a greater proliferation rate and thereby also higher survival rate compared to tumours expressing lower or minimal receptor level.
  • The presence of GHR in endothelial cells of vascular neoplasm indicates that they are target cells and GH is of importance in the proliferation of vascular tumour angiogenesis.

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  • [ErratumIn] Anticancer Res. 2008 Mar-Apr;28(2b):1439
  • (PMID = 18225592.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Receptors, Somatotropin; 9002-72-6 / Growth Hormone
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72. Peramiquel L, Barnadas MA, Sancho J, Curell R, Alonso MC, Fuentes MJ, Pernas S, Gómez A, Alomar A: [Angiosarcoma in an irradiated breast: a case description]. Actas Dermosifiliogr; 2005 Nov;96(9):602-6
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  • [Title] [Angiosarcoma in an irradiated breast: a case description].
  • [Transliterated title] Angiosarcoma en mama irradiada: descripción de un caso.
  • Post-radiotherapy cutaneous angiosarcomas have been described in different locations, including the breast.
  • We present a case of cutaneous angiosarcoma of the breast, diagnosed 6 years after a carcinoma of the breast had been treated with radiation.
  • Considering the patient's symptoms, history and the changes observed via mammography, it was decided to completely excise the lesion followed by a simple mastectomy, with the diagnosis of angiosarcoma being confirmed.
  • The patient was later treated with paclitaxel, and the disease was apparently controlled.
  • Despite this fact, two years and one month later, the angiosarcoma recurred on the internal area of the mastectomy scar.
  • This complication usually appears 5-10 years after treatment with radiotherapy, so angiosarcoma should be ruled out if any angiomatous lesions later appear on skin that had been irradiated.
  • [MeSH-major] Breast Neoplasms / etiology. Breast Neoplasms / radiotherapy. Carcinoma, Ductal, Breast / radiotherapy. Hemangiosarcoma / etiology. Neoplasms, Radiation-Induced / etiology. Skin Neoplasms / etiology

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  • (PMID = 16476306.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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73. Rodríguez-Bujaldón A, Vázquez-Bayo MC, Galán-Gutiérrez M, Jiménez-Puya R, Vélez García-Nieto A, Moreno-Giménez JC, Vidal-Jiménez A, Barroso-Casamitjana E: [Angiosarcoma in chronic lymphedema]. Actas Dermosifiliogr; 2006 Oct;97(8):525-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiosarcoma in chronic lymphedema].
  • [Transliterated title] Angiosarcoma sobre linfedema crónico.
  • Angiosarcoma that develops on a limb with chronic lymphedema is called Stewart-Treves syndrome.
  • The first corresponds to a typical syndrome of Stewart-Treves in an 83-year-old woman who was diagnosed of angiosarcoma in a chronic lymphedema territory secondary to mastectomy and radiotherapy due to breast cancer.
  • The second case is much rarer, since it is a case of diffuse angiosarcoma of the leg in a 42-year-old man with a history of lymphedema.
  • [MeSH-major] Hemangiosarcoma / etiology. Lymphedema / complications
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antibiotics, Antineoplastic / administration & dosage. Antibiotics, Antineoplastic / therapeutic use. Antineoplastic Agents, Alkylating / administration & dosage. Antineoplastic Agents, Alkylating / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Arm. Doxorubicin / administration & dosage. Doxorubicin / therapeutic use. Female. Humans. Ifosfamide / administration & dosage. Ifosfamide / therapeutic use. Immunohistochemistry. Leg. Male. Skin / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / drug therapy. Skin Neoplasms / etiology. Skin Neoplasms / pathology. Skin Neoplasms / radiotherapy. Treatment Outcome

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  • (PMID = 17067532.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Antineoplastic Agents, Alkylating; 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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74. Lee SW, Song CY, Gi YH, Kang SB, Kim YS, Nam SW, Lee DS, Kim JO: Hepatic angiosarcoma manifested as recurrent hemoperitoneum. World J Gastroenterol; 2008 May 14;14(18):2935-8
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  • [Title] Hepatic angiosarcoma manifested as recurrent hemoperitoneum.
  • Angiosarcoma is a rare tumor that account for less than 1% of all sarcomas.
  • Although hepatic angiosarcoma usually presents with unspecific symptoms, it rapidly progresses and has a high mortality.
  • We report a rare case of primary hepatic angiosarcoma manifested as recurrent hemoperitoneum.
  • [MeSH-major] Hemangiosarcoma / complications. Hemoperitoneum / diagnosis. Hemoperitoneum / etiology. Liver Neoplasms / complications
  • [MeSH-minor] Aged. Disease Progression. Female. Humans. Recurrence

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  • (PMID = 18473427.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2710744
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75. Deetjen AG, Conradi G, Möllmann S, Hamm CW, Dill T: Cardiac angiosarcoma diagnosed and characterized by cardiac magnetic resonance imaging. Cardiol Rev; 2006 Mar-Apr;14(2):101-3
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  • [Title] Cardiac angiosarcoma diagnosed and characterized by cardiac magnetic resonance imaging.
  • New imaging methods like cardiac magnetic resonance imaging (MRI) play an important role in the early diagnosis and differentiation of cardiac masses.
  • By presenting the case of a 63-year-old woman with an angiosarcoma of the right atrium and its characteristic findings on cardiac MRI, the role of this new imaging method is emphasized.
  • [MeSH-major] Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Magnetic Resonance Imaging, Cine / methods

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  • (PMID = 16493248.001).
  • [ISSN] 1061-5377
  • [Journal-full-title] Cardiology in review
  • [ISO-abbreviation] Cardiol Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Kaddu S, Wolf I, Horn M, Kerl H: Epithelioid sarcoma with angiomatoid features: report of an unusual case arising in an elderly patient within a burn scar. J Cutan Pathol; 2008 Mar;35(3):324-8
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  • [Title] Epithelioid sarcoma with angiomatoid features: report of an unusual case arising in an elderly patient within a burn scar.
  • Epithelioid sarcoma (ES) is a rare, aggressive soft tissue tumor with a characteristic predilection for adolescents and young adults, and a tendency to occur on distal extremities.
  • The overall histopathologic features were consistent with a diagnosis of ES.
  • In this uncommon setting, this tumor should be especially distinguished from epithelioid hemangioendothelioma and epithelioid angiosarcoma.
  • [MeSH-major] Angiomatosis / pathology. Burns / pathology. Cicatrix / pathology. Sarcoma / pathology. Soft Tissue Neoplasms / pathology


77. Maeda T, Tateishi U, Hasegawa T, Ojima H, Arai Y, Sugimura K: Primary hepatic angiosarcoma on coregistered FDG PET and CT images. AJR Am J Roentgenol; 2007 Jun;188(6):1615-7
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  • [Title] Primary hepatic angiosarcoma on coregistered FDG PET and CT images.
  • [MeSH-major] Fluorodeoxyglucose F18. Hemangiosarcoma / radiography. Liver Neoplasms / radiography. Positron-Emission Tomography / methods. Subtraction Technique. Tomography, X-Ray Computed / methods

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  • (PMID = 17515384.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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78. Chapas AM, Askarian F, Demierre MF, Stefanato CM: Well-differentiated angiosarcoma of the scalp: an unusual clinical presentation. J Am Acad Dermatol; 2005 Feb;52(2 Suppl 1):58-9
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  • [Title] Well-differentiated angiosarcoma of the scalp: an unusual clinical presentation.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Hemangiosarcoma / pathology. Scalp / pathology. Skin Neoplasms / pathology

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  • (PMID = 15692518.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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79. Ettl T, Kleinheinz J, Mehrotra R, Schwarz S, Reichert TE, Driemel O: Infraorbital cutaneous angiosarcoma: a diagnostic and therapeutic dilemma. Head Face Med; 2008;4:18
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  • [Title] Infraorbital cutaneous angiosarcoma: a diagnostic and therapeutic dilemma.
  • BACKGROUND: A cutaneous angiosarcoma is a rare malignant tumour of vascular endothelial cells with aggressive clinical behaviour and poor prognosis.
  • Diagnosis is often delayed due to its variable and often benign clinical appearance.
  • Histopathologic examination of the specimen diagnosed a cutaneous angiosarcoma.
  • Neither, finally achieved negative margins on permanent sections, nor a following chemotherapy could prevent the recurrence of the disease after five months and the patient's dead 21 months after the first diagnosis.
  • [MeSH-major] Facial Neoplasms / pathology. Hemangiosarcoma / pathology. Neoplasm Recurrence, Local / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biopsy, Needle. Chemotherapy, Adjuvant. Combined Modality Therapy. Disease Progression. Fatal Outcome. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Radiotherapy, Adjuvant. Reoperation

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  • [Cites] Cancer. 2003 Nov 15;98(10):2251-6 [14601096.001]
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  • (PMID = 18694495.001).
  • [ISSN] 1746-160X
  • [Journal-full-title] Head & face medicine
  • [ISO-abbreviation] Head Face Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2533304
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80. Kuppahally SS, Litwin SE, Michaels AD: Endomyocardial biopsy of right atrial angiosarcoma guided by intracardiac echocardiography. Cardiol Res Pract; 2010;2010:681726
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  • [Title] Endomyocardial biopsy of right atrial angiosarcoma guided by intracardiac echocardiography.

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  • [Cites] Eur J Echocardiogr. 2007 Dec;8(6):505-6 [17015040.001]
  • [Cites] J Am Soc Echocardiogr. 2002 May;15(5):475-7 [12019433.001]
  • (PMID = 20585357.001).
  • [ISSN] 2090-0597
  • [Journal-full-title] Cardiology research and practice
  • [ISO-abbreviation] Cardiol Res Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2878669
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81. Andrews S, Wilcoxon R, Benda J, Jacobson G: Angiosarcoma following MammoSite partial breast irradiation. Breast Cancer Res Treat; 2010 Nov;124(1):279-82
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  • [Title] Angiosarcoma following MammoSite partial breast irradiation.
  • Angiosarcoma is a rare tumor of endothelial origin which commonly arises in small blood or lymphatic vessels.
  • To our knowledge, there are no reported cases in the literature or MammoSite registry which describe the occurrence of angiosarcoma in the treated breast following MammoSite brachytherapy.
  • This is a case report of a 74 year old female who developed angiosarcoma 4 years after receiving MammoSite balloon brachytherapy following surgical resection of a T1mic N0 M0 infiltrating ductal carcinoma.
  • [MeSH-major] Brachytherapy / adverse effects. Breast Neoplasms / radiotherapy. Carcinoma, Ductal, Breast / radiotherapy. Hemangiosarcoma / etiology. Neoplasms, Radiation-Induced / etiology

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  • (PMID = 20496164.001).
  • [ISSN] 1573-7217
  • [Journal-full-title] Breast cancer research and treatment
  • [ISO-abbreviation] Breast Cancer Res. Treat.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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82. Altamirano JC, Gratz SR, Wolnik KA: Investigation of pyrrolizidine alkaloids and their N-oxides in commercial comfrey-containing products and botanical materials by liquid chromatography electrospray ionization mass spectrometry. J AOAC Int; 2005 Mar-Apr;88(2):406-12
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  • PAs are also carcinogenic to animals, and they have been linked to the development of hepatocellular and skin squamous cell carcinomas as well as liver angiosarcomas.

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  • (PMID = 15859063.001).
  • [ISSN] 1060-3271
  • [Journal-full-title] Journal of AOAC International
  • [ISO-abbreviation] J AOAC Int
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Alkaloids; 0 / Indicators and Reagents; 0 / Oxides; 0 / Plant Preparations; 0 / Pyrrolizidine Alkaloids
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83. Patton KT, Deyrup AT, Weiss SW: Atypical vascular lesions after surgery and radiation of the breast: a clinicopathologic study of 32 cases analyzing histologic heterogeneity and association with angiosarcoma. Am J Surg Pathol; 2008 Jun;32(6):943-50
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  • [Title] Atypical vascular lesions after surgery and radiation of the breast: a clinicopathologic study of 32 cases analyzing histologic heterogeneity and association with angiosarcoma.
  • In 4 cases, endothelial atypia, consisting of nuclear and nucleolar enlargement, was noted.
  • Of the 21 patients, 17 are alive without disease, 1 is alive with disease, 1 died of breast carcinoma, 1 died of unknown causes, and 1 showed progressive histologic changes in the AVLs over a period of 5 years resulting in a well-differentiated angiosarcoma.
  • Follow-up in 8 patients with VT AVL (2 to 181 mo; mean 40 mo) disclosed that 6 were alive and well, but 2 of the 4 patients whose lesions displayed endothelial atypia had additional complications.
  • One patient underwent a mastectomy that revealed extensive residual AVL and the second developed a high-grade angiosarcoma after 14 months.
  • There seems to be an association of AVL with angiosarcoma that differs depending on the histologic features, with the VT AVLs having the higher risk.
  • In the 2 patients who developed angiosarcoma, morphologic evidence suggested AVLs to be a precursor rather than simply a risk factor.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology. Neoplasms, Radiation-Induced / pathology

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  • (PMID = 18551753.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Wang ZS, Zhan N, Xiong CL, Li H: Primary epithelioid angiosarcoma of the male breast: report of a case. Surg Today; 2007;37(9):782-6
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  • [Title] Primary epithelioid angiosarcoma of the male breast: report of a case.
  • We report a case of primary epithelioid angiosarcoma of the male breast.
  • Histopathological examination and immunohistochemical analysis confirmed a diagnosis of primary epithelioid angiosarcoma of the male breast, without axillary lymph node metastasis.
  • We review the relevant literature on this rare malignant tumor.
  • [MeSH-major] Breast Neoplasms, Male / pathology. Hemangiosarcoma / pathology. Neoplasms, Glandular and Epithelial / pathology

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  • (PMID = 17713733.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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85. Arribas-Garcia I, Domínguez MF, Alcalá-Galiano A, García AF, Valls JC, De Rasche EN: Oral primary angiosarcoma of the lower lip mucosa: report of a case in a 15-year-old boy. Head Neck; 2008 Oct;30(10):1384-8
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  • [Title] Oral primary angiosarcoma of the lower lip mucosa: report of a case in a 15-year-old boy.
  • BACKGROUND: Angiosarcomas are rare soft tissue malignant tumors with dismal prognosis.
  • METHODS AND RESULTS: We present the case of an inferior lip mucosal low-grade angiosarcoma in a 15-year-old boy treated exclusively with surgery.
  • Prompt and accurate diagnosis with adequate imaging modalities and multidisciplinary treatment are crucial for optimal management of these neoplasms.
  • [MeSH-major] Hemangiosarcoma. Lip Neoplasms

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  • [Copyright] Copyright (c) 2008 Wiley Periodicals, Inc. Head Neck 2008.
  • (PMID = 18286486.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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86. Stanislas S: [Splenic pathology. Case 5. Splenic angiosarcoma]. Ann Pathol; 2010 Jun;30(3):223-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Splenic pathology. Case 5. Splenic angiosarcoma].
  • [Transliterated title] Pathologie splénique. Cas n(o) 5. Angiosarcome primitif splénique.
  • [MeSH-major] Hemangiosarcoma / pathology. Splenic Neoplasms / pathology

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  • (PMID = 20621601.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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87. Gajda M, Hommann M, Böttcher J, Henning K, Kaiser WA, Settmacher U, Katenkamp D: [Primary liposarcoma of the liver--a rare mesenchymal tumor]. Z Gastroenterol; 2007 Dec;45(12):1241-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Most often angiosarcomas have been reported.
  • [MeSH-major] Liposarcoma / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Cell Nucleus / pathology. Diagnosis, Differential. Female. Hepatectomy. Humans. Liver / pathology. Magnetic Resonance Imaging. Middle Aged

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  • (PMID = 18080225.001).
  • [ISSN] 0044-2771
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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88. Wiedemann D, Bonaros N, Schachner T, Bonatti J, Laufer G, Kocher A: Cardiac angiosarcoma with reconstruction of the right atrium. Heart Surg Forum; 2010 Dec;13(6):E397-8
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  • [Title] Cardiac angiosarcoma with reconstruction of the right atrium.
  • A tumor highly suspicious for an angiosarcoma was identified by computed tomography and was suggestive of infiltration into the superior vena cava (SVC) and the majority of the right atrium.
  • [MeSH-major] Cardiovascular Surgical Procedures / methods. Heart Neoplasms / surgery. Hemangiosarcoma / surgery. Reconstructive Surgical Procedures / instrumentation. Reconstructive Surgical Procedures / methods

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  • (PMID = 21169152.001).
  • [ISSN] 1522-6662
  • [Journal-full-title] The heart surgery forum
  • [ISO-abbreviation] Heart Surg Forum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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89. Lin N, Uchi H, Moroi Y, Fukiwake N, Dainichi T, Takeuchi S, Takahara M, Tu Y, Furue M, Urabe K: Significance of the expression of phosphorylated signal transducer and activator of transcription-3, -Akt, and -cyclin D1 in angiosarcoma. J Dermatol Sci; 2007 Oct;48(1):64-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Significance of the expression of phosphorylated signal transducer and activator of transcription-3, -Akt, and -cyclin D1 in angiosarcoma.
  • [MeSH-major] Cyclin D1 / metabolism. Hemangiosarcoma / metabolism. Proto-Oncogene Proteins c-akt / metabolism. STAT3 Transcription Factor / metabolism. Vascular Neoplasms / metabolism
  • [MeSH-minor] Biopsy. Endothelial Cells / metabolism. Endothelial Cells / pathology. Gene Expression Regulation, Neoplastic. Granuloma, Pyogenic / metabolism. Granuloma, Pyogenic / pathology. Hemangioma, Capillary / metabolism. Hemangioma, Capillary / pathology. Humans. Vascular Diseases / metabolism. Vascular Diseases / pathology


90. Newell-Fugate A, Lane E: Periaortic haemangiosarcoma in an African wild dog (Lycaon pictus). J S Afr Vet Assoc; 2009 Jun;80(2):108-10
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  • [Title] Periaortic haemangiosarcoma in an African wild dog (Lycaon pictus).
  • Histologically, the mass was consistent with a haemangiosarcoma.
  • [MeSH-major] Canidae. Heart Neoplasms / veterinary. Hemangiosarcoma / veterinary

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  • (PMID = 19831274.001).
  • [ISSN] 1019-9128
  • [Journal-full-title] Journal of the South African Veterinary Association
  • [ISO-abbreviation] J S Afr Vet Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] South Africa
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91. Sopena P, Uruburu E, Abreu P, Giménez A, Martínez B, Martínez C: [Angiosarcoma of the scalp: extension study with PET-CT]. Rev Esp Med Nucl; 2010 Mar-Apr;29(2):91-2
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  • [Title] [Angiosarcoma of the scalp: extension study with PET-CT].
  • [Transliterated title] Angiosarcoma de cuero cabelludo: estudio de extensión con PET-TAC.
  • [MeSH-major] Bone Neoplasms / secondary. Head and Neck Neoplasms / pathology. Hemangiosarcoma / secondary. Positron-Emission Tomography. Scalp / pathology. Skin Neoplasms / secondary. Tomography, X-Ray Computed


92. Yoon TY, Kim HJ, Kim JW, Kim MK, Lee JY: Bowen's disease concealed by purpura. J Dermatol; 2007 Jan;34(1):65-7
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  • [Title] Bowen's disease concealed by purpura.
  • Bowen's disease (BD) is a squamous cell carcinoma in situ characterized by a well-demarcated scaly erythematous thin plaque with an irregular outline.
  • However, angiosarcoma has not usually been mentioned in the differential diagnosis of BD before.
  • Herein, we describe two cases of BD presenting as purpura on the scalp of the elderly with an initial clinical suspicion of angiosarcoma.
  • [MeSH-major] Bowen's Disease / complications. Purpura / complications. Scalp. Skin Neoplasms / complications
  • [MeSH-minor] Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans

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  • (PMID = 17204105.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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93. Lo Presti M, Mazzella C, Monfrecola A, Falleti J: Angiosarcoma mimicking rhinophyma. Dermatol Res Pract; 2010;2010:365173
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  • [Title] Angiosarcoma mimicking rhinophyma.
  • During that time the patient underwent several dermatological consultations, and all produced the same diagnosis: rhinophyma.
  • Punch biopsy was performed, and histopathology and immunohistochemical studies were consistent with cutaneous angiosarcoma.
  • This is the report of a face angiosarcoma with an unusual and very deceptive clinical presentation.

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  • (PMID = 20631905.001).
  • [ISSN] 1687-6113
  • [Journal-full-title] Dermatology research and practice
  • [ISO-abbreviation] Dermatol Res Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2902059
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94. Ravi V, Benjamin RS: Systemic therapy for cardiac sarcomas. Methodist Debakey Cardiovasc J; 2010 Jul-Sep;6(3):57-60
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  • [Title] Systemic therapy for cardiac sarcomas.
  • Cardiac sarcomas create 2 risks: local problems and metastatic disease.
  • Most frequently, the histologies are angiosarcoma and high-grade pleomorphic unclassified sarcoma (formerly called MFH or malignant fibrous histiocytoma).
  • There is also a clinical-pathological entity without distinctive histological features of tumors that originate in the pulmonary artery and are referred to as pulmonary artery sarcomas or intimal sarcomas of the pulmonary artery.
  • Conventional wisdom indicates that soft-tissue sarcomas are poorly responsive to chemotherapy.
  • Attempts to concentrate on the local problem only with therapies up to and including cardiac transplantation have been unsuccessful due to the high rate of fatal metastatic disease.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Heart Neoplasms / drug therapy. Sarcoma / drug therapy

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  • (PMID = 20834213.001).
  • [ISSN] 1947-6094
  • [Journal-full-title] Methodist DeBakey cardiovascular journal
  • [ISO-abbreviation] Methodist Debakey Cardiovasc J
  • [Language] eng
  • [Publication-type] Journal Article; Portraits
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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95. Kajo K, Macháleková K, Pauer M: [Retiform hemangioendotelioma in a 8-year-old girl--case report]. Cesk Patol; 2009 Jul;45(3):72-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Retiform hemangioendotelioma in a 8-year-old girl--case report].
  • Retiform hemangioendothelioma (RHE) is a rare vascular tumoriform lesion characterized by rete testis--like vascular structures.
  • RHE belongs to a group of vascular tumors of intermediate malignancy and together with Dabska tumor form a category of so-called hobnail hemangioendotheliomas.
  • Histologically, the tumor consisted of a net of vessel formations with retiform appearance and prominent endothelial nuclei.
  • Other benign and malignant vascular lesions with hobnail cells (hemangioma, angiosarcoma) have to be considered in differential diagnosis.
  • [MeSH-major] Hemangioendothelioma / pathology. Vascular Neoplasms / pathology

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  • (PMID = 19764161.001).
  • [ISSN] 1210-7875
  • [Journal-full-title] Československá patologie
  • [ISO-abbreviation] Cesk Patol
  • [Language] slo
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Lewis Blood-Group System
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96. Astudillo L, Cron C, Gomez-Brouchet A, Couret B, Arlet-Suau E: [Angiosarcoma of the aorta]. Rev Med Interne; 2007 Oct;28(10):718-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiosarcoma of the aorta].
  • [Transliterated title] Angiosarcome épithélioïde de l'aorte.
  • Histopathology revealed an epithelioid angiosarcoma of the aorta.

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  • (PMID = 17587469.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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97. Craddock KJ, Labonte S, Ghazarian D: Anaplastic Kaposi sarcoma resembling epithelioid angiosarcoma in an HIV-positive man. Eur J Dermatol; 2008 May-Jun;18(3):358-9
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  • [Title] Anaplastic Kaposi sarcoma resembling epithelioid angiosarcoma in an HIV-positive man.
  • [MeSH-major] AIDS-Related Opportunistic Infections / diagnosis. HIV Infections / complications. Hemangiosarcoma / diagnosis. Herpesvirus 8, Human. Sarcoma, Kaposi / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Nuclear Proteins / metabolism. Phosphoproteins / metabolism. Skin / pathology


98. Raina V, Sengar M, Shukla NK, Deo SS, Mohanty BK, Sharma D, Ray R, Das P, Rath GK: Complete response from thalidomide in angiosarcoma after treatment of breast cancer. J Clin Oncol; 2007 Mar 1;25(7):900-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Complete response from thalidomide in angiosarcoma after treatment of breast cancer.
  • [MeSH-major] Breast Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Thalidomide / therapeutic use

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  • (PMID = 17327613.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 4Z8R6ORS6L / Thalidomide
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99. Pazona JF, Gupta R, Wysock J, Schaeffer AJ, Smith ND: Angiosarcoma of bladder: long-term survival after multimodal therapy. Urology; 2007 Mar;69(3):575.e9-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of bladder: long-term survival after multimodal therapy.
  • Angiosarcoma of the bladder is extremely rare and carries a dismal prognosis because of the uniformly high-grade and aggressive tumor biology of the neoplasm.
  • We report the long-term disease-free survival of 1 patient, treated with multimodal therapy, whom we have previously reported on.
  • Six years after the initial presentation, the patient died, and the postmortem analysis revealed no evidence of residual disease.
  • Our case represents the longest reported survival of a patient with angiosarcoma of the bladder.
  • [MeSH-major] Hemangiosarcoma / surgery. Urinary Bladder Neoplasms / surgery

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  • (PMID = 17382176.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31
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