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71. Devillers C, Vanhooteghem O, de la Brassinne M: [Lymphedema and cutaneous diseases]. Rev Med Suisse; 2007 Dec 5;3(136):2802-5
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  • [Title] [Lymphedema and cutaneous diseases].
  • Clinical changes of skin can occur.
  • The major cutaneous complications are infections, dysimmune diseases and neoplasms; the most serious is angiosarcoma.
  • [MeSH-major] Lymphedema / complications. Skin Diseases / etiology
  • [MeSH-minor] Dermatomycoses / etiology. Erysipelas / etiology. Hemangiosarcoma. Humans. Intertrigo / microbiology. Pemphigoid, Bullous / etiology. Skin Neoplasms / etiology. Sweet Syndrome / etiology

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  • (PMID = 18183816.001).
  • [ISSN] 1660-9379
  • [Journal-full-title] Revue médicale suisse
  • [ISO-abbreviation] Rev Med Suisse
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
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72. Pfeiffer DF, Bode-Lesniewska B: Fine needle aspiration biopsy diagnosis of angiosarcoma after breast-conserving therapy for carcinoma supported by use of a cell block and immunohistochemistry. Acta Cytol; 2006 Sep-Oct;50(5):553-6
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  • [Title] Fine needle aspiration biopsy diagnosis of angiosarcoma after breast-conserving therapy for carcinoma supported by use of a cell block and immunohistochemistry.
  • BACKGROUND: Angiosarcoma is a rare malignant soft tissue tumor occurring at various sites as either a primary or secondary event.
  • Primary angiosarcoma of the breast is an unusual tumor, counting for 1 in 1700-2,000 primary malignant tumors of this organ.
  • An increasing number of secondary angiosarcomas involving skin and breast.
  • CASE: Angiosarcoma arose 6 years after breast-conserving therapy for invasive carcinoma in a 69-year-old woman.
  • Fine needle aspiration of several small, reddish, intradermal nodules over the treated area revealed malignant cells with an endothelial immunophenotype in the cel block, yielding the diagnosis of angiosarcoma, subsequently confired in a mastectomy speciman.
  • CONCLUSION: Fine needle aspiration, supported by ancillary techniques, such as cell block and immunohistochemistry, allows the cytologic diagnosis of an angiosarcoma and differentiates it from a carcinoma recurrence.
  • [MeSH-major] Breast / pathology. Breast Neoplasms / diagnosis. Carcinoma, Ductal, Breast / diagnosis. Hemangiosarcoma / diagnosis. Neoplasms, Second Primary / diagnosis. Radiotherapy / adverse effects
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Biopsy, Fine-Needle. Cell Nucleus / pathology. Diagnosis, Differential. Epithelial Cells / pathology. Female. Humans. Immunohistochemistry / methods. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 17017445.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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73. Schlauder SM, Bowers J, Morgan MB: A surreptitious sinister sarcoma. Am J Dermatopathol; 2007 Jun;29(3):311-2; discussion 313
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  • [Title] A surreptitious sinister sarcoma.
  • Angiosarcoma is an exceedingly rare endothelial-derived sarcoma that, when seen, usually presents as an expanding bruise-like patch or violaceous papule/nodule on the head of an elderly patient.
  • Herein, we present the histologic features of an unusual case that defied initial diagnosis.
  • [MeSH-major] Hemangiosarcoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 17519636.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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4. Lee BA, Wanat KA, Eisen AZ: Cutaneous angiosarcoma of the knee: a case report and review of the literature. Cutis; 2009 Feb;83(2):91-4
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  • [Title] Cutaneous angiosarcoma of the knee: a case report and review of the literature.
  • Cutaneous angiosarcoma is a rare, malignant, vascular tumor that usually occurs in the scalp and face region of elderly white men.
  • We report an unusual case of angiosarcoma occurring on the knee of a 70-year-old white woman with a strong family history of malignant melanoma in the absence of any known predisposing features.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Knee Joint / pathology. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans

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  • (PMID = 19326694.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 19
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75. Wong J, Huerter C: Clinicopathologic challenge. Angiosarcoma of the scalp. Int J Dermatol; 2008 Sep;47(9):881-3
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  • [Title] Clinicopathologic challenge. Angiosarcoma of the scalp.
  • [MeSH-major] Hemangiosarcoma / pathology. Scalp. Skin Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Biopsy, Needle. Early Diagnosis. Female. Humans. Immunohistochemistry. Neoplasm Staging. Prognosis. Risk Assessment

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  • (PMID = 18937648.001).
  • [ISSN] 1365-4632
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Park JW, Serafica-Karen C, Das K: Fine-needle aspiration of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver: A diagnostic dilemma. Diagn Cytopathol; 2010 Oct;38(10):768-71
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  • [Title] Fine-needle aspiration of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver: A diagnostic dilemma.
  • Radiation therapy is a significant risk factor for the development of angiosarcoma.
  • With the increase in breast conservation treatment, the incidence of cutaneous radiation-induced angiosarcoma of the breast is rising.
  • If the angiosarcoma demonstrates epithelioid features, the tumor cells may present a diagnostic dilemma on fine-needle aspiration cytology.
  • We present a case of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver and a review of the literature.
  • [MeSH-minor] Breast Neoplasms / metabolism. Breast Neoplasms / secondary. Carcinoma in Situ / radiotherapy. Carcinoma in Situ / surgery. Carcinoma, Ductal, Breast / radiotherapy. Carcinoma, Ductal, Breast / surgery. Cytodiagnosis. Diagnosis, Differential. Female. Hemangiosarcoma / metabolism. Hemangiosarcoma / secondary. Humans. Immunohistochemistry. Mastectomy, Segmental. Middle Aged. Radiotherapy, Adjuvant / adverse effects. Skin Neoplasms / metabolism. Skin Neoplasms / pathology

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  • [Copyright] © 2010 Wiley-Liss, Inc.
  • (PMID = 20187111.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Angiosarcoma of the breast
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77. Rajinikanth J, Gaikwad P, Raj JP, Tirkey AJ, Muthusami JC: Angiosarcoma of the scalp. Otolaryngol Head Neck Surg; 2008 Feb;138(2):255-6
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  • [Title] Angiosarcoma of the scalp.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Hemangiosarcoma / pathology. Scalp. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Biopsy. Combined Modality Therapy / methods. Diagnosis, Differential. Humans. Male

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  • (PMID = 18241726.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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78. Constantinou C, Sheldon D: Papillary endothelial hyperplasia of the adrenal gland: report of a case and review of the literature. Am Surg; 2008 Sep;74(9):813-6
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  • Papillary endothelial hyperplasia (PEH) is a benign vascular proliferative process most frequently seen in the skin and integument, but may involve any of the visceral organs.
  • Pathologic differentiation from angiosarcoma can be a difficult task requiring evaluation by an experienced pathologist.

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  • (PMID = 18807668.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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79. Kunkel T, Mylonas I, Mayr D, Friese K, Sommer HL: Recurrence of secondary angiosarcoma in a patient with post-radiated breast for breast cancer. Arch Gynecol Obstet; 2008 Nov;278(5):497-501
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  • [Title] Recurrence of secondary angiosarcoma in a patient with post-radiated breast for breast cancer.
  • INTRODUCTION: Angiosarcoma of the breast is a rare finding.
  • Two different subtypes of angiosarcomas have been described: (a) the Stewart-Treves syndrome and (b) the cutaneous post-radiation angiosarcoma.
  • We report a case where both types of angiosarcoma occurred.
  • CASE REPORT: At first, an angiosarcoma affecting parenchyma of the breast was observed after radiotherapy following breast conserving therapy and a history of lymphoedema of the radiated area.
  • Additionally, a subsequent local recurrence of the angiosarcoma of the skin after mastectomy and complete resection of the primary angiosarcoma was diagnosed.
  • Patients should be pointed to this possible complication of radiotherapy and transferred to seek medical advice immediately in case of skin lesion in the irradiated area: even many years after radiotherapy.
  • Additionally, every oncologist should be aware of this rare complication as quick diagnosis and prompt surgical treatment is indispensable due to the aggressive entity of angiosarcoma.
  • [MeSH-major] Breast Neoplasms / therapy. Hemangiosarcoma / therapy. Neoplasm Recurrence, Local / therapy. Skin Neoplasms / therapy

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  • (PMID = 18305948.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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80. Salameire D, Templier I, Charles J, Pinel N, Morand P, Leccia MT, Lantuejoul S: An "anaplastic" Kaposi's sarcoma mimicking a Stewart-Treves syndrome. A case report and a review of literature. Am J Dermatopathol; 2008 Jun;30(3):265-8
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  • [Title] An "anaplastic" Kaposi's sarcoma mimicking a Stewart-Treves syndrome. A case report and a review of literature.
  • Cutaneous angiosarcoma (AGS) developing in a lymphedematous arm, after lymphadenectomy in the context of breast cancer, is the definition of the classical Stewart-Treves syndrome.
  • Like AGS, many tumors such as Kaposi's sarcoma (KS) could develop in chronic lymphedema.
  • The final diagnosis was an "anaplastic" KS mimicking a Stewart-Treves syndrome.
  • "Anaplastic" KS is a rare histological form of nodular KS, which mimics a cutaneous AGS but classically expresses herpes human virus 8.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Lymphangiosarcoma / diagnosis. Lymphedema / pathology. Sarcoma, Kaposi / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. DNA, Neoplasm / analysis. Diagnosis, Differential. Female. Herpesvirus 8, Human / isolation & purification. Humans. Middle Aged. Syndrome. Viral Proteins / metabolism

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  • (PMID = 18496429.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Viral Proteins; 0 / assembly protein, Human herpesvirus 8
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81. Lucas DR: Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesion. Arch Pathol Lab Med; 2009 Nov;133(11):1804-9
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  • [Title] Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesion.
  • Angiosarcoma, one of the least common sarcomas, has become increasingly important because of its association with radiation therapy, especially for breast cancer.
  • Most are sporadic, presenting as cutaneous tumors in the scalp/face of elderly patients.
  • However, angiosarcoma has a wide anatomic distribution including soft tissue, visceral organ, and osseous locations.
  • Radiation-associated angiosarcoma typically presents as a cutaneous tumor several years posttherapy.
  • The latency for radiation-associated mammary angiosarcoma is relatively short, sometimes less than 3 years.
  • Atypical vascular lesion refers to a small, usually lymphatic-type vascular proliferation in radiated skin.
  • Although most atypical vascular lesions pursue a benign course, they recur and very rarely progress to angiosarcoma.
  • Distinguishing this lesion from well-differentiated angiosarcoma in a biopsy can be challenging, especially because areas indistinguishable from atypical vascular lesion are found adjacent to angiosarcoma.
  • [MeSH-major] Hemangioma / pathology. Hemangiosarcoma / pathology. Neoplasms, Radiation-Induced / pathology. Skin Neoplasms / pathology. Vascular Diseases / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Breast Neoplasms / radiotherapy. Female. Humans. Skin / blood supply

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  • (PMID = 19886715.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 12
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82. Grewal JS, Daniel AR, Carson EJ, Catanzaro AT, Shehab TM, Tworek JA: Rapidly progressive metastatic multicentric epithelioid angiosarcoma of the small bowel: a case report and a review of literature. Int J Colorectal Dis; 2008 Aug;23(8):745-56
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  • [Title] Rapidly progressive metastatic multicentric epithelioid angiosarcoma of the small bowel: a case report and a review of literature.
  • BACKGROUND: Angiosarcoma is a rare high-grade neoplasm that frequently involves the skin and subcutaneous tissue.
  • Rarely, angiosarcoma can occur in the gastrointestinal tract where it frequently exhibits multicentric epithelioid morphology.
  • DESIGN: We report a case of multicentric epithelioid angiosarcoma (EAS) of the small intestine in a 73-year-old male patient who presented with weakness and melena, and was found to have bleeding lesions in the small intestine on upper gastrointestinal endoscopy.
  • In addition to this case, we extensively reviewed the clinical and pathological features of previously reported cases of angiosarcoma of the small intestine in the English literature since 1970.
  • He died within 4 months of the diagnosis.
  • CONCLUSIONS: Angiosarcoma, especially of the deep tissues and the gastrointestinal tract, is very aggressive and rapidly metastatic.
  • The survival rate in these patients is extremely poor, and most patients die within 6 months to 1 year of the diagnosis.
  • [MeSH-major] Hemangiosarcoma / pathology. Hemangiosarcoma / secondary. Intestinal Neoplasms / pathology. Intestine, Small / pathology

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  • (PMID = 18080128.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
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83. Kasper DA, Smetanick MT, Ermolovich T: Angiosarcoma clinically resembling morpheaform basal cell carcinoma. Dermatol Surg; 2008 Oct;34(10):1407-10
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  • [Title] Angiosarcoma clinically resembling morpheaform basal cell carcinoma.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Hemangiosarcoma / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Face. Female. Humans. Skin Ulcer / diagnosis

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  • (PMID = 18637812.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Vasanawala MS, Wang Y, Quon A, Gambhir SS: F-18 fluorodeoxyglucose PET/CT as an imaging tool for staging and restaging cutaneous angiosarcoma of the scalp. Clin Nucl Med; 2006 Sep;31(9):534-7
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  • [Title] F-18 fluorodeoxyglucose PET/CT as an imaging tool for staging and restaging cutaneous angiosarcoma of the scalp.
  • Cutaneous angiosarcoma of the scalp is a rare highly aggressive malignant tumor that typically afflicts elderly patients and commonly presents with extensive local spread and distant metastasis.
  • Distant metastases favor lung, liver, lymph nodes, and skin.
  • We report the case of a 70-year-old man diagnosed with multifocal angiosarcoma of the scalp.
  • PET/CT imaging with F-18 2-fluoro-2-deoxyglucose (F-18 FDG) not only showed avid FDG uptake by an angiosarcoma (SUVmax = 10.7), but also simultaneously showed local extension of multifocal lesions with periosteal involvement and excluded metastatic abdominal nodal disease.
  • Evaluation of more cases of this subset of soft tissue sarcoma with FDG PET/CT may suggest a possible role in not only staging angiosarcomas to determine the extent of local as well as distant disease, but also to potentially help determine response to therapy and early recognition of local or distant recurrence.
  • [MeSH-major] Fluorodeoxyglucose F18. Hemangiosarcoma / diagnosis. Hemangiosarcoma / radionuclide imaging. Neoplasm Staging / methods. Positron-Emission Tomography / methods. Radiopharmaceuticals. Scalp / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / radionuclide imaging. Tomography, X-Ray Computed / methods

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  • (PMID = 16921276.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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85. Chen SY, Takeuchi S, Urabe K, Hayashida S, Kido M, Tomoeda H, Uchi H, Dainichi T, Takahara M, Shibata S, Tu YT, Furue M, Moroi Y: Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous angiosarcoma and pyogenic granuloma. J Cutan Pathol; 2008 Aug;35(8):722-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous angiosarcoma and pyogenic granuloma.
  • BACKGROUND: Activating transcription factor-2/Activator protein-1 (AP-1), Signal transducer and activator of transcription-3 and p53 are important regulators of cellular proliferation, apoptosis, differentiation in the pathogenesis of many human tumors, but the expression of phosphorylated (p)-activating transcription factor-2 (p-ATF2), phosphorylated (p)-signal transducer and activator of transcription-3 (p-STAT3) and p53 family (p63 and p73) has not been investigated in cutaneous angiosarcoma (CAS) and pyogenic granuloma (PG) so far.
  • OBJECTIVES: To investigate the expression of p-ATF2, p-STAT3 and p53 and its family in cutaneous vascular tumors (CAS and PG).
  • The p-ATF2-, p-STAT3- and p53 expression (% positive cells) in CAS and PG were significantly higher than in normal dermal vessels, but none of these transcription factors distinguished malignant (CAS)- from benign (PG) vascular tumor.
  • CONCLUSIONS: The present study suggests that overexpression of p-ATF2, p-STAT3 and possibly p53, but not p63 or p73, may contribute to the tumorigenesis of cutaneous vascular tumors.
  • [MeSH-major] Activating Transcription Factor 2 / biosynthesis. Gene Expression Regulation, Neoplastic. Granuloma, Pyogenic / metabolism. Hemangiosarcoma / metabolism. STAT3 Transcription Factor / biosynthesis. Skin Neoplasms / metabolism. Tumor Suppressor Protein p53 / biosynthesis


86. Chiu LS, Wong KH, Lam WY, Luk NM, Lo KK: Angiosarcoma of the scrotum after treatment of cancer of the rectum. Clin Exp Dermatol; 2006 Sep;31(5):706-7
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  • [Title] Angiosarcoma of the scrotum after treatment of cancer of the rectum.
  • [MeSH-major] Hemangiosarcoma / etiology. Rectal Neoplasms / therapy. Scrotum. Skin Neoplasms / etiology. Testicular Neoplasms / etiology

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  • (PMID = 16901314.001).
  • [ISSN] 0307-6938
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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87. Bhutoria B, Konar A, Chakrabarti S, Das S: Retiform hemangioendothelioma with lymph node metastasis: a rare entity. Indian J Dermatol Venereol Leprol; 2009 Jan-Feb;75(1):60-2
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  • Retiform hemangioendothelioma (RH) is a rare, recently described, unique kind of low grade angiosarcoma.
  • The tumor chiefly originates from the skin and subcutaneous tissue and has a tendency to recur locally.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Hemangioendothelioma / pathology. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology

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  • (PMID = 19172034.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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88. de Giorgi V, Santi R, Grazzini M, Papi F, Gori A, Rossari S, Massi D, Lotti T: Synchronous angiosarcoma, melanoma and morphea of the breast skin 14 years after radiotherapy for mammary carcinoma. Acta Derm Venereol; 2010 May;90(3):283-6
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  • [Title] Synchronous angiosarcoma, melanoma and morphea of the breast skin 14 years after radiotherapy for mammary carcinoma.
  • We describe here the case of a 68-year-old woman who developed synchronous cutaneous angiosarcoma, melanoma and morphea of the breast skin and the local area, 14 years after radiotherapy for breast carcinoma.
  • Given the risk of post-radiation secondary primaries in breast cancer patients, long-term surveillance is necessary, with particular attention being paid to skin changes in the irradiation field.
  • Radiation-induced morphea is a rare complication in which immunological abnormalities may stimulate malignant transformation.
  • [MeSH-major] Breast Neoplasms / radiotherapy. Carcinoma / radiotherapy. Hemangiosarcoma / etiology. Melanoma / etiology. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / etiology. Scleroderma, Localized / etiology. Skin Neoplasms / etiology
  • [MeSH-minor] Aged. Female. Humans. Radiotherapy / adverse effects. Skin / pathology. Skin / radiation effects. Time Factors


89. Buschmann A, Lehnhardt M, Toman N, Preiler P, Salakdeh MS, Muehlberger T: Surgical treatment of angiosarcoma of the scalp: less is more. Ann Plast Surg; 2008 Oct;61(4):399-403
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  • [Title] Surgical treatment of angiosarcoma of the scalp: less is more.
  • In 19 patients, we performed a resection of the external table with the defect being covered immediately by a split skin graft.
  • In view of the difficult diagnosis, an often delayed therapy and the rapid formation of metastases, a time-saving procedure with a low rate of complications should be given preference over other reconstructive methods.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Hemangiosarcoma / surgery. Reconstructive Surgical Procedures / methods. Scalp / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Female. Humans. Length of Stay. Male. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery. Palliative Care. Radiotherapy, Adjuvant. Skin Transplantation. Wound Healing


90. Bacchi CE, Silva TR, Zambrano E, Plaza J, Suster S, Luzar B, Lamovec J, Pizzolitto S, Falconieri G: Epithelioid angiosarcoma of the skin: a study of 18 cases with emphasis on its clinicopathologic spectrum and unusual morphologic features. Am J Surg Pathol; 2010 Sep;34(9):1334-43
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  • [Title] Epithelioid angiosarcoma of the skin: a study of 18 cases with emphasis on its clinicopathologic spectrum and unusual morphologic features.
  • We report 18 cases of cutaneous angiosarcoma with predominant or exclusive epithelioid morphology.
  • In elderly patients scalp or facial lesions and cutaneous lesions arising within irradiated breast skin predominated.
  • Our data show that epithelioid cutaneous angiosarcoma may have a broad morphological spectrum, raising interpretive challenges on microscopy.
  • [MeSH-major] Epithelioid Cells / pathology. Hemangiosarcoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 20697249.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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91. Glazebrook KN, Magut MJ, Reynolds C: Angiosarcoma of the breast. AJR Am J Roentgenol; 2008 Feb;190(2):533-8
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  • [Title] Angiosarcoma of the breast.
  • CONCLUSION: With the increasing use of breast conservation therapy for breast cancer, reports of postirradiation angiosarcoma have increased.
  • Both primary and secondary angiosarcomas may present with bruiselike skin discoloration, which may delay the diagnosis.
  • [MeSH-major] Breast Neoplasms / diagnosis. Diagnostic Imaging / methods. Hemangiosarcoma / diagnosis. Image Enhancement / methods

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  • (PMID = 18212243.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 18
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92. Jain M, Singh S, Agarwal K: Spindle cell neoplasm of skin: diagnostic dilemma. Indian J Pathol Microbiol; 2007 Oct;50(4):814-6
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  • [Title] Spindle cell neoplasm of skin: diagnostic dilemma.
  • Poorly differentiated, spindle cell malignancies, on sun damaged skin frequently pose a diagnostic challenge for pathologists.
  • The vast majority of these neoplasms ultimately are diagnosed as either atypical fibroxanthoma (AFX), spindle cell melanoma (SCM), and very rarely as spindle cell squamous cell carcinoma (SCSCC), leiomyosarcoma or angiosarcoma.
  • Light microscopic clues may suggest one of these neoplasms, but subtle and overlapping characteristics often render precise diagnosis impossible based on morphological features alone.
  • Immunohistochemistry therefore is necessary to firmly and accurately diagnose the majority of spindle cell malignancies on sun damaged skin.
  • [MeSH-major] Sarcoma / diagnosis. Sarcoma / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Keratins / analysis. Melanoma / pathology. S100 Proteins / analysis. Vimentin / analysis. Xanthomatosis / pathology

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  • (PMID = 18306566.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / S100 Proteins; 0 / Vimentin; 68238-35-7 / Keratins
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93. Kisseberth WC, Vail DM, Yaissle J, Jeglum KA, Couto CG, Ward H, Khanna C, Obradovich JE: Phase I clinical evaluation of carboplatin in tumor-bearing cats: a Veterinary Cooperative Oncology Group study. J Vet Intern Med; 2008 Jan-Feb;22(1):83-8
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  • There was 1 complete response (cutaneous hemangiosarcoma) and 6 partial responses (4 injection site sarcomas, 1 oral squamous cell carcinoma, 1 lymphoma).

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  • (PMID = 18289293.001).
  • [ISSN] 0891-6640
  • [Journal-full-title] Journal of veterinary internal medicine
  • [ISO-abbreviation] J. Vet. Intern. Med.
  • [Language] ENG
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; AYI8EX34EU / Creatinine; BG3F62OND5 / Carboplatin
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94. Jowett AJ, Parvin SD: Angiosarcoma in an area of lipodermatosclerosis. Ann R Coll Surg Engl; 2008 Jul;90(5):W15-6
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  • [Title] Angiosarcoma in an area of lipodermatosclerosis.
  • An area within this broke down as a result of an angiosarcoma rather than the more probable: formation of a venous ulcer.
  • [MeSH-major] Hemangiosarcoma / etiology. Leg Ulcer / complications. Skin Neoplasms / etiology

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  • [Cites] J Surg Oncol. 2000 Mar;73(3):182-8 [10738275.001]
  • [Cites] CA Cancer J Clin. 1981 Sep-Oct;31(5):284-99 [6793218.001]
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  • (PMID = 18634723.001).
  • [ISSN] 1478-7083
  • [Journal-full-title] Annals of the Royal College of Surgeons of England
  • [ISO-abbreviation] Ann R Coll Surg Engl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2645745
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95. Selim A, Khachemoune A, Lockshin NA: Angiosarcoma: a case report and review of the literature. Cutis; 2005 Nov;76(5):313-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma: a case report and review of the literature.
  • Angiosarcoma is an aggressive neoplasm that predominantly affects elderly patients.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Humans. Male. Nose / pathology. Nose / surgery. Radiotherapy, Adjuvant

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  • (PMID = 16422466.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 28
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96. Gonzalez MJ, Koehler MM, Satter EK: Angiosarcoma of the scalp: a case report and review of current and novel therapeutic regimens. Dermatol Surg; 2009 Apr;35(4):679-84
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  • [Title] Angiosarcoma of the scalp: a case report and review of current and novel therapeutic regimens.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Head and Neck Neoplasms / therapy. Hemangiosarcoma / therapy. Neoplasm Recurrence, Local / therapy. Surgical Flaps
  • [MeSH-minor] Aged, 80 and over. Combined Modality Therapy. Humans. Male. Radiotherapy, Adjuvant. Scalp. Skin Transplantation

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  • (PMID = 19415795.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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97. Chen JL, Mok KT, Tseng HH, Wang BW, Liu SI, Chen CW: Duodenal angiosarcoma: an unusual cause of severe gastrointestinal bleeding. J Chin Med Assoc; 2007 Aug;70(8):352-5
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  • [Title] Duodenal angiosarcoma: an unusual cause of severe gastrointestinal bleeding.
  • Angiosarcoma is a rare soft-tissue neoplasm that occurs most often in the skin and the subcutaneous tissues but very rarely in the gastrointestinal tract.
  • We report a case of primary intestinal angiosarcoma with severe gastrointestinal bleeding.
  • The pathology was consistent with angiosarcoma of the duodenum.
  • [MeSH-major] Duodenal Neoplasms / complications. Gastrointestinal Hemorrhage / etiology. Hemangiosarcoma / complications

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  • (PMID = 17698438.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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98. Brenn T, Fletcher CD: Postradiation vascular proliferations: an increasing problem. Histopathology; 2006 Jan;48(1):106-14
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  • The occurrence of cutaneous vascular lesions is a rare but well-documented complication of radiation treatment and may be associated with significant morbidity as well as mortality.
  • The spectrum of postradiation vascular lesions is wide and ranges from atypical vascular lesions with reportedly benign clinical behaviour to frank cutaneous angiosarcoma.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Radiation-Induced / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Skin / blood supply. Skin / pathology. Skin / radiation effects

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  • (PMID = 16359542.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 80
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99. Asgari MM, Cockerell CJ, Weitzul S: The head-tilt maneuver: a clinical aid in recognizing head and neck angiosarcomas. Arch Dermatol; 2007 Jan;143(1):75-7
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  • BACKGROUND: Cutaneous angiosarcoma is a rare, life-threatening tumor that is often initially misdiagnosed.
  • This delay in diagnosis can affect tumor growth, metastatic potential, and prognosis.
  • [MeSH-major] Head Movements. Head and Neck Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Skin / pathology
  • [MeSH-minor] Diagnosis, Differential. Face. Head-Down Tilt. Humans. Male. Torsion Abnormality

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  • (PMID = 17224545.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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100. Kaminaka C, Yamamoto Y, Yonei N, Furukawa F: Phenol application to angiosarcomas: implications and histologic studies. Int J Dermatol; 2009 May;48(5):470-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Cutaneous angiosarcoma (AS) is an aggressive endothelial sarcoma that arises in elderly people.
  • AIMS: To evaluate the efficacy of phenol application for the treatment of AS, and to examine the histologic changes in three cases of cutaneous AS with phenol application.
  • METHODS: After phenol application, biopsy specimens were collected from three patients with cutaneous AS.
  • Paraffin-embedded sections of the skin specimens were then stained with hematoxylin and eosin.
  • [MeSH-major] Hemangiosarcoma / drug therapy. Hemangiosarcoma / pathology. Phenol / therapeutic use. Sclerosing Solutions / therapeutic use. Skin Neoplasms / drug therapy. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Apoptosis / drug effects. Biopsy. Female. Humans. In Situ Nick-End Labeling. Skin / pathology

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  • (PMID = 19416375.001).
  • [ISSN] 1365-4632
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Sclerosing Solutions; 339NCG44TV / Phenol
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