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16. Verge J, Albiol J, Navas M, Martín C: [Primary angiosarcoma of the spleen with liver metastases. Case report and literature review]. Cir Esp; 2005 Jul;78(1):50-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary angiosarcoma of the spleen with liver metastases. Case report and literature review].
  • [Transliterated title] Angiosarcoma primario de bazo con metástasis hepáticas: presentación de un caso y revisión de la bibliografía.
  • Angiosarcomas of the spleen are infrequent tumors that often present with liver metastases.
  • Immunohistochemical markers can aid preoperative diagnosis since radiological and ultrasonographic images are fairly nonspecific.
  • [MeSH-major] Hemangiosarcoma / secondary. Hemangiosarcoma / surgery. Liver Neoplasms / secondary. Liver Neoplasms / surgery. Splenic Neoplasms / pathology. Splenic Neoplasms / surgery

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  • (PMID = 16420791.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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17. Park JW, Serafica-Karen C, Das K: Fine-needle aspiration of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver: A diagnostic dilemma. Diagn Cytopathol; 2010 Oct;38(10):768-71
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  • [Title] Fine-needle aspiration of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver: A diagnostic dilemma.
  • Radiation therapy is a significant risk factor for the development of angiosarcoma.
  • With the increase in breast conservation treatment, the incidence of cutaneous radiation-induced angiosarcoma of the breast is rising.
  • If the angiosarcoma demonstrates epithelioid features, the tumor cells may present a diagnostic dilemma on fine-needle aspiration cytology.
  • We present a case of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver and a review of the literature.
  • [MeSH-major] Biopsy, Fine-Needle. Liver Neoplasms / secondary. Neoplasms, Radiation-Induced / pathology
  • [MeSH-minor] Breast Neoplasms / metabolism. Breast Neoplasms / secondary. Carcinoma in Situ / radiotherapy. Carcinoma in Situ / surgery. Carcinoma, Ductal, Breast / radiotherapy. Carcinoma, Ductal, Breast / surgery. Cytodiagnosis. Diagnosis, Differential. Female. Hemangiosarcoma / metabolism. Hemangiosarcoma / secondary. Humans. Immunohistochemistry. Mastectomy, Segmental. Middle Aged. Radiotherapy, Adjuvant / adverse effects. Skin Neoplasms / metabolism. Skin Neoplasms / pathology

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  • [Copyright] © 2010 Wiley-Liss, Inc.
  • (PMID = 20187111.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Angiosarcoma of the breast
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18. Bonaccorsi-Riani E, Lerut JP: Liver transplantation and vascular tumours. Transpl Int; 2010 Jul;23(7):686-91
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  • [Title] Liver transplantation and vascular tumours.
  • Based on analysis of the literature and of the audited ELITA (European Liver Intestinal Transplant Association)-ELTR (European Liver Transplant Registry) data, the place of liver transplantation (LT) in the treatment of vascular tumours is discussed.
  • Hepatic epithelioid haemangioendothelioma has currently become a good indication for LT with 5- and 10-year post-LT patient survival rates of 83% and 74% respectively and 5- and 10-year recurrence-free survival rates of 82% and 64% respectively.
  • The value of LT in the treatment of infantile haemangioendothelioma is more difficult to evaluate because of the very reduced number of reported cases and because of the often difficult differential diagnosis with angiosarcoma.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / surgery. Hemangiosarcoma / surgery. Liver Neoplasms / surgery. Liver Transplantation. Vascular Neoplasms / surgery
  • [MeSH-minor] Biopsy. Child, Preschool. Diagnostic Errors. Hepatectomy. Humans. Infant. Liver / pathology. Liver / surgery. Neoplasm Recurrence, Local. Registries. Survival Rate

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  • (PMID = 20492619.001).
  • [ISSN] 1432-2277
  • [Journal-full-title] Transplant international : official journal of the European Society for Organ Transplantation
  • [ISO-abbreviation] Transpl. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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19. Kim HR, Rha SY, Cheon SH, Roh JK, Park YN, Yoo NC: Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma. Ann Oncol; 2009 Apr;20(4):780-7
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  • [Title] Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma.
  • BACKGROUND: Primary hepatic angiosarcoma is a very rare malignancy with a poor prognosis.
  • PATIENTS AND METHODS: Among 11,939 patients diagnosed with primary hepatic tumors from January 1985 to December 2007 at two centers, five patients were diagnosed with primary hepatic angiosarcoma.
  • Two of four patients who received chemotherapy died <3 months after diagnosis, but the other two patients survived >6 months.
  • This case study may aid in planning chemotherapy for patients with advanced hepatic angiosarcoma.

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  • (PMID = 19179547.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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20. Schwartz J, Hatch J, Shaaban A, Hutson W: Education and Imaging. Hepatobiliary and pancreatic: angiosarcoma of the liver. J Gastroenterol Hepatol; 2010 May;25(5):1016
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Education and Imaging. Hepatobiliary and pancreatic: angiosarcoma of the liver.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Liver Neoplasms / diagnosis

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  • (PMID = 20546460.001).
  • [ISSN] 1440-1746
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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31. Wang J, Li Q, Sun Y, Cui YL: [A case of angiosarcoma developed from liver hamartomas]. Zhonghua Gan Zang Bing Za Zhi; 2006 Sep;14(9):717
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  • [Title] [A case of angiosarcoma developed from liver hamartomas].
  • [MeSH-major] Hamartoma / pathology. Hemangiosarcoma / pathology. Liver Neoplasms / pathology

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  • (PMID = 16996000.001).
  • [ISSN] 1007-3418
  • [Journal-full-title] Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
  • [ISO-abbreviation] Zhonghua Gan Zang Bing Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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32. Zhou ML, Yan FH, Ye F, Xiong Z, Wang JH, Ji Y: [Images of primary hepatic angiosarcomas]. Zhonghua Gan Zang Bing Za Zhi; 2008 Feb;16(2):136-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Images of primary hepatic angiosarcomas].
  • [MeSH-major] Hemangiosarcoma / radiography. Liver Neoplasms / radiography. Tomography, X-Ray Computed

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  • (PMID = 18304433.001).
  • [ISSN] 1007-3418
  • [Journal-full-title] Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
  • [ISO-abbreviation] Zhonghua Gan Zang Bing Za Zhi
  • [Language] chi
  • [Publication-type] Journal Article
  • [Publication-country] China
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33. Deyrup AT, Tighiouart M, Montag AG, Weiss SW: Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. Am J Surg Pathol; 2008 Jun;32(6):924-7
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  • Epithelioid hemangioendothelioma (EHE) of soft tissue is a distinctive vascular tumor that has been variously considered a tumor of borderline malignancy and low-grade angiosarcoma.
  • Eleven patients (22%) had metastatic disease affecting lung (6), lymph node (4), liver (2), and bone, retroperitoneum, and soft tissue (1 each).
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 18551749.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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4. den Hoed ID, Granzen B, Granzen B, Aronson DC, Pauwels P, de Kraker J, van Heurn LW: Metastasized angiosarcoma of the spleen in a 2-year-old girl. Pediatr Hematol Oncol; 2005 Jul-Aug;22(5):387-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasized angiosarcoma of the spleen in a 2-year-old girl.
  • Primary angiosarcoma of the spleen is rare and the prognosis is very poor.
  • The authors present a 2-year-old girl with spontaneous rupture of splenic angiosarcoma.
  • At diagnosis there were liver metastases.
  • After splenectomy she received chemotherapy with ifosfamide, vincristine, and actinomycine D combined with a partial liver resection.
  • She remained in complete remission over 2 years from diagnosis.
  • [MeSH-major] Hemangiosarcoma / secondary. Liver Neoplasms / secondary. Splenic Neoplasms / pathology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child, Preschool. Female. Hepatectomy. Humans. Neoplasm Metastasis. Prognosis. Remission Induction

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  • (PMID = 16020128.001).
  • [ISSN] 0888-0018
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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35. Gambino G, Mannone T, Rizzo A, Scio A, Branca M, Airò Farulla M, Guccione M, Spallitta IS, Nicoli N: Adrenal epithelioid angiosarcoma: a case report. Chir Ital; 2008 May-Jun;60(3):463-7
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  • [Title] Adrenal epithelioid angiosarcoma: a case report.
  • We report what to the best of our knowledge is the first case of primary angiosarcoma of the adrenal gland.
  • Computed tomography revealed a suspected rupture of a liver neoplasm and surgical treatment was performed.
  • At laparotomy there was no evidence of liver tumour but a large mass was found in the right adrenal gland.
  • [MeSH-major] Adrenal Gland Neoplasms. Hemangiosarcoma

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  • (PMID = 18709789.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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96. Oe A, Habu D, Kawabe J, Torii K, Kawamura E, Kotani J, Hayashi T, Sakaguchi H, Shiomi S: A case of diffuse hepatic angiosarcoma diagnosed by FDG-PET. Ann Nucl Med; 2005 Sep;19(6):519-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of diffuse hepatic angiosarcoma diagnosed by FDG-PET.
  • Fluorine-18 2-deoxy-2-fluoro-D-glucose (FDG)-positron emission tomography (PET) showed diffuse abnormal accumulation throughout the entire liver.
  • She was diagnosed by histopathological examination as having hepatic angiosarcoma causing veno-occlusive disease (VOD).
  • This is the first report of hepatic angiosarcoma with FDG-PET.
  • [MeSH-major] Fluorodeoxyglucose F18. Hemangiosarcoma / complications. Hemangiosarcoma / radionuclide imaging. Hepatic Veno-Occlusive Disease / etiology. Hepatic Veno-Occlusive Disease / radionuclide imaging. Liver Neoplasms / complications. Liver Neoplasms / radionuclide imaging

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  • (PMID = 16248391.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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97. Hertl M, Cosimi AB: Liver transplantation for malignancy. Oncologist; 2005 Apr;10(4):269-81
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  • [Title] Liver transplantation for malignancy.
  • Liver transplantation for hepatic malignancies has emerged from an exotic and desperate approach to a well-documented and proven treatment modality for these unfortunate patients.
  • Currently, <10% of all liver transplants performed are for hepatocellular cancer (HCC).
  • Similarly, liver transplantation for HCC in the adult population yields good results for patients whose tumor masses do not exceed the Milan criteria.
  • Epitheloid hemangioendothelioma is also an appropriate indication for liver transplantation, unlike angiosarcoma.
  • Metastatic liver disease is not an indication for liver transplantation, with the exception of cases in which the primary is a neuroendocrine tumor, for which liver transplantation can result in long-term survival and even cure in a number of patients.
  • And finally, while gallbladder cancers are never an indication for liver transplantation, rare cases of cholangiocellular cancer might qualify if aggressive combination therapies, including chemotherapy and radiotherapy followed by OLT, are carried through.
  • Survival in these selected patients can approach that for patients with cholestatic liver disease.
  • [MeSH-major] Bile Duct Neoplasms / surgery. Carcinoma, Hepatocellular / surgery. Liver Neoplasms / surgery. Liver Transplantation
  • [MeSH-minor] Cholangiocarcinoma / mortality. Cholangiocarcinoma / pathology. Cholangiocarcinoma / surgery. Hemangioendothelioma, Epithelioid / mortality. Hemangioendothelioma, Epithelioid / pathology. Hemangioendothelioma, Epithelioid / surgery. Hepatoblastoma / mortality. Hepatoblastoma / pathology. Hepatoblastoma / surgery. Humans. Medical Oncology / trends. Neoplasm Metastasis. Patient Selection. Survival Rate. Treatment Outcome. Waiting Lists


98. Burns C, Harrison K, Jammer B, Zuccarini D, Lafrance B: A cancer incidence and mortality study of Dow Chemical Canada Inc. manufacturing sites. Occup Med (Lond); 2005 Dec;55(8):618-24
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  • There were no cases of angiosarcoma of the liver.
  • These cancers were included in the 12 deaths with malignant mesothelioma at Sarnia.
  • CONCLUSION: Consistent with the earlier report, lower mortality rates were observed for the major classifications of disease and malignant neoplasms.
  • Past asbestos exposure prior to 1980 is probably a contributor to the deaths due to malignant mesothelioma but is not reflected in lung cancer mortality.

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  • (PMID = 16174663.001).
  • [ISSN] 0962-7480
  • [Journal-full-title] Occupational medicine (Oxford, England)
  • [ISO-abbreviation] Occup Med (Lond)
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 1332-21-4 / Asbestos
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99. Schima W, Kölblinger C, Eisenhuber-Stadler E, Kulinna-Cosentini C, Ba-Ssalamah A: [Diseases of the hepatobiliary system as a cause of acute abdomen]. Radiologe; 2010 Mar;50(3):252, 254-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Diseases of the liver and biliary system are common causes of acute abdominal pain and gallstone disease predisposes to cholecystitis and cholangiolithiasis.
  • Pyogenic, amebic and fungal liver abscesses are reliably diagnosed with MDCT which can also be used for interventional radiologic therapy of liver abscesses by percutaneous aspiration or drainage procedures.
  • The second most common cause of liver rupture after blunt trauma is spontaneous rupture of hypervascular liver tumors (i.e., HCC, adenoma, angiosarcoma) and due to medical procedures.
  • [MeSH-major] Abdomen, Acute / diagnosis. Abdomen, Acute / etiology. Biliary Tract Diseases / complications. Biliary Tract Diseases / diagnosis. Diagnostic Imaging / methods. Liver Diseases / complications. Liver Diseases / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans

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  • (PMID = 20157692.001).
  • [ISSN] 1432-2102
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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100. Di Bisceglie AM, Osmack P, Brunt EM: Chemoprevention of hepatocellular carcinoma: use of tamoxifen in an animal model of hepatocarcinogenesis. J Lab Clin Med; 2005 Mar;145(3):134-8
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  • HCC often occurs against a background of liver disease, tends to present at an advanced stage, and has a poor prognosis, suggesting that it is an ideal target for chemoprevention.
  • To this end, we induced liver tumors by injecting ethyl-nitrosourea in 6-week-old male B6C3F1 mice.
  • All liver lesions (altered foci, adenomata, HCC) occurred significantly less frequently in the tamoxifen-treated group than the group given only ethylnitrosourea (HCC developed in 2 of 47 (4%) vs 11 of 44 (25%); P < .001).
  • On the other hand, retinoic acid appeared to increase the number of liver tumors, and in 2 animals angiosarcoma developed.
  • [MeSH-major] Anticarcinogenic Agents / therapeutic use. Carcinoma, Hepatocellular / prevention & control. Liver Neoplasms, Experimental / prevention & control. Tamoxifen / therapeutic use
  • [MeSH-minor] Adenoma, Liver Cell / pathology. Adenoma, Liver Cell / prevention & control. Animals. Chemoprevention. Disease Models, Animal. Ethylnitrosourea. Male. Mice. Mice, Inbred Strains. Precancerous Conditions / pathology. Precancerous Conditions / prevention & control. Tretinoin / therapeutic use

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  • (PMID = 15871304.001).
  • [ISSN] 0022-2143
  • [Journal-full-title] The Journal of laboratory and clinical medicine
  • [ISO-abbreviation] J. Lab. Clin. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticarcinogenic Agents; 094ZI81Y45 / Tamoxifen; 5688UTC01R / Tretinoin; P8M1T4190R / Ethylnitrosourea
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