[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 153
1. Bhati CS, Bhatt AN, Starkey G, Hubscher SG, Bramhall SR: Acute liver failure due to primary angiosarcoma: a case report and review of literature. World J Surg Oncol; 2008 Sep 30;6:104
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acute liver failure due to primary angiosarcoma: a case report and review of literature.
  • BACKGROUND: Hepatic angiosarcoma is a primary sarcoma of the liver, accounting for only 2% of all primary hepatic malignancies.
  • Acute liver failure is an extremely rare presentation of a primary liver tumour.
  • CASE PRESENTATION: We report a case of a seventy year-old man who presented with a very short period of jaundice leading to fulminant hepatic failure (FHF).
  • On further investigation he was found to have primary angiosarcoma of liver.
  • CONCLUSION: The treatment outcomes for hepatic angiosarcoma are poor, we discuss the options available and the need for prompt investigation and establishment of a diagnosis.
  • [MeSH-major] Hemangiosarcoma / complications. Liver Failure, Acute / etiology. Liver Neoplasms / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Hepatogastroenterology. 2007 Mar;54(74):533-5 [17523315.001]
  • [Cites] J Clin Gastroenterol. 2005 Apr;39(4):339-43 [15758630.001]
  • [Cites] Sarcoma. 2007;2007:90169 [18288242.001]
  • [Cites] Am J Transplant. 2006 Feb;6(2):392-7 [16426326.001]
  • [Cites] Gut. 1987 Jun;28(6):668-74 [3623214.001]
  • [Cites] Am Surg. 2000 Dec;66(12):1153-7 [11149588.001]
  • [Cites] Curr Oncol Rep. 2002 Nov;4(6):515-9 [12354365.001]
  • [Cites] Radiographics. 1994 Jan;14(1):153-66; quiz 167-8 [8128048.001]
  • [Cites] Tumori. 1978 Feb 28;64(1):45-53 [349809.001]
  • [Cites] Cancer. 2007 Apr 1;109(7):1391-6 [17315167.001]
  • [Cites] Eur J Gastroenterol Hepatol. 2003 Nov;15(11):1235-40 [14560159.001]
  • [Cites] Cancer. 1976 Apr;37(4):1965-72 [177182.001]
  • [Cites] Dig Dis Sci. 2003 Apr;48(4):677-82 [12741455.001]
  • [Cites] Ann Oncol. 2001 Jul;12(7):1005-10 [11521784.001]
  • [Cites] Br J Surg. 2000 Nov;87(11):1500-5 [11091236.001]
  • [Cites] Eur Radiol. 2000;10(1):129-33 [10663729.001]
  • [Cites] Gastroenterology. 1981 Apr;80(4):820-5 [7202952.001]
  • [Cites] J Gastroenterol. 2004 Aug;39(8):804-6 [15338379.001]
  • [Cites] Hepatology. 2008 Apr;47(4):1401-15 [18318440.001]
  • [Cites] Minerva Chir. 1997 Oct;52(10):1141-6 [9471563.001]
  • [Cites] Clin Liver Dis. 2001 Feb;5(1):219-57, viii [11218917.001]
  • [Cites] Gut. 1998 Apr;42(4):576-80 [9616324.001]
  • [Cites] Surg Gynecol Obstet. 1968 Jul;127(1):1-11 [5657778.001]
  • [Cites] Am J Gastroenterol. 1995 Dec;90(12):2207-9 [8540518.001]
  • [Cites] Tumori. 2006 Jul-Aug;92(4):354-7 [17036530.001]
  • [Cites] Hepatology. 1983 May-Jun;3(3):428-32 [6573294.001]
  • (PMID = 18826593.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0701304
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 28
  • [Other-IDs] NLM/ PMC2567320
  •  go-up   go-down


2. Hoshi N, Mukai S, Oishi M, Takano M, Shinzawa J, Watanabe S, Yamazaki S, Sakuma H, Ohira H, Obara K, Kasukawa R, Sato Y: A case of hepatic angiosarcoma supplied by both hepatic artery and portal vein. Fukushima J Med Sci; 2006 Jun;52(1):13-9
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of hepatic angiosarcoma supplied by both hepatic artery and portal vein.
  • Liver neoplasms, whether they are benign or malignant, are usually fed by the hepatic artery.
  • We experienced a case of hepatic angiosarcoma supplied by both hepatic artery and portal vein.
  • Since there are currently no specific laboratory tests to diagnose hepatic angiosarcoma, it is important to detect suspect cases from imaging features.
  • This unique hemodynamic property was detected on computed tomography (CT) during hepatic arteriography and CT during hepatic arterioportography.
  • If any imaging examinations indicate the liver tumor to be fed by the portal vein, hepatic angiosarcoma should be suspected.
  • [MeSH-major] Hemangiosarcoma / blood supply. Hepatic Artery / radiography. Liver Neoplasms / blood supply. Portal Vein / radiography
  • [MeSH-minor] Angiography. Humans. Liver / blood supply. Liver / pathology. Male. Middle Aged. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16995350.001).
  • [ISSN] 0016-2590
  • [Journal-full-title] Fukushima journal of medical science
  • [ISO-abbreviation] Fukushima J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


3. Egea Valenzuela J, López Poveda MJ, Pérez Fuenzalida FJ, Garre Sánchez C, Martínez Barba E, Carballo Alvarez F: Hepatic angiosarcoma. Presentation of two cases. Rev Esp Enferm Dig; 2009 Jun;101(6):430-4, 434-7
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma. Presentation of two cases.
  • Hepatic angiosarcoma is a rare primary tumor of the liver with a mesenchymal origin.
  • Diagnosis is difficult because clinical manifestations and imaging studies are inconclusive.
  • In many cases a diagnosis is obtained during necropsy, not being apparent during the course of disease.
  • When clinical manifestations begin progression is often fast, and possibilities for curative treatment are limited.We report two cases of hepatic angiosarcoma.
  • In the first one, our patient had an insidious initial course, and then suddenly presented with hepatic failure followed by acute respiratory distress.
  • A diagnosis was reached during necropsy.
  • In the second case, we initiated the study of a chronic liver disease using fine-needle aspiration biopsy, which showed findings suggestive of hepatic angiosarcoma.
  • [MeSH-major] Hemangiosarcoma. Liver Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19630468.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


Advertisement
4. Gatta G, Ciccolallo L, Kunkler I, Capocaccia R, Berrino F, Coleman MP, De Angelis R, Faivre J, Lutz JM, Martinez C, Möller T, Sankila R, EUROCARE Working Group: Survival from rare cancer in adults: a population-based study. Lancet Oncol; 2006 Feb;7(2):132-40
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • FINDINGS: Overall 5-year relative survival was good (ie, >65%) for placental choriocarcinoma (85.4% [95% CI 81.4-89.5]), thyroid medullary carcinoma (72.4% [69.2-75.5]), ovarian germ-cell cancer (73.0% [70.0-76.0]), lung carcinoid (70.1% [67.3-72.9]), and cervical adenocarcinoma (65.5% [64.3-66.6]); intermediate (ie, 35-65%) for testicular cancer at age 65 years or older (64.0% [59.3-68.7]), sarcoma of extremities (60.0% [58.9-61.2]), digestive-system endocrine cancers (55.6% [54.9-56.3]), anal squamous-cell carcinoma (53.1% [51.5-54.8]), and uterine sarcoma (43.5% [42.0-44.9]); low for carcinoma of adrenal-gland cortex (32.7% [28.3-37.2]) and bladder squamous-cell carcinoma (20.4% [18.8-22.0]); and poor for angiosarcoma of liver (6.4% [1.8-11.0]) and mesothelioma (4.7% [4.3-5.2]).
  • Survival significantly improved over time for ovarian germ-cell cancer, sarcomas of extremities, digestive-system endocrine tumours, anal squamous-cell carcinoma, and angiosarcoma of liver.

  • MedlinePlus Health Information. consumer health - Rare Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16455477.001).
  • [ISSN] 1470-2045
  • [Journal-full-title] The Lancet. Oncology
  • [ISO-abbreviation] Lancet Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


5. Sanz-García C, Matilla-Peña A, Nogales-Rincón O, Núñez-Martínez O, Clemente-Ricote G: [Hepatoportal sclerosis and liver angiosarcoma: an infrequent association with a possible common etiology]. Gastroenterol Hepatol; 2005 Nov;28(9):555-7
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hepatoportal sclerosis and liver angiosarcoma: an infrequent association with a possible common etiology].
  • [Transliterated title] Esclerosis hepatoportal y angiosarcoma hepático: una asociación infrecuente y una posible etiología común.
  • We describe the case of a 58-year-old woman with idiopathic hepatoportal sclerosis, who was admitted to our service due to impairment of liver function, with rapid clinical worsening and finally the development of multiorgan failure.
  • Autopsy showed a diffuse liver angiosarcoma with splenic metastases.
  • The patient had no history of domestic or occupational exposure to substances involved in the development of hepatoportal sclerosis or liver angiosarcoma.
  • The development of liver angiosarcoma in a patient with hepatoportal sclerosis is exceptional, even though both diseases may have a common etiology.
  • [MeSH-major] Hemangiosarcoma / complications. Hepatic Veno-Occlusive Disease / complications. Liver Neoplasms / complications. Multiple Organ Failure / etiology. Portal Vein / pathology
  • [MeSH-minor] Autopsy. Fatal Outcome. Female. Humans. Hypertension, Portal / etiology. Liver Failure / etiology. Middle Aged. Sclerosis. Splenic Neoplasms / secondary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16277963.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


6. Leowardi C, Hormann Y, Hinz U, Wente MN, Hallscheidt P, Flechtenmacher C, Buchler MW, Friess H, Schwarzbach MH: Ruptured angiosarcoma of the liver treated by emergency catheter-directed embolization. World J Gastroenterol; 2006 Feb 7;12(5):804-8
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ruptured angiosarcoma of the liver treated by emergency catheter-directed embolization.
  • Angiosarcoma is a rare primary malignant neoplasm of the liver with a poor prognosis.
  • Here, we report a case of a patient with a ruptured hepatic angiosarcoma which was treated by emergency catheter-directed embolization, followed by left-sided hemihepatectomy.
  • [MeSH-major] Embolization, Therapeutic. Hemangiosarcoma / therapy. Liver Neoplasms / therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Eur Arch Otorhinolaryngol. 2005 Mar;262(3):173-7 [15133686.001]
  • [Cites] Ann Radiol (Paris). 1996;39(2):89-103 [8794571.001]
  • [Cites] Eur J Surg Oncol. 2004 May;30(4):421-7 [15063896.001]
  • [Cites] Mod Pathol. 2000 Sep;13(9):978-87 [11007038.001]
  • [Cites] Digestion. 2000;62(4):280-3 [11070413.001]
  • [Cites] Am Surg. 2000 Dec;66(12):1153-7 [11149588.001]
  • [Cites] Rofo. 2001 Aug;173(8):763-5 [11570248.001]
  • [Cites] Rofo. 2003 Mar;175(3):307-8 [12674093.001]
  • [Cites] Dig Dis Sci. 2003 Apr;48(4):677-82 [12741455.001]
  • [Cites] Chin Med J (Engl). 2003 Feb;116(2):318-20 [12775258.001]
  • [Cites] J Am Acad Dermatol. 2003 Sep;49(3):532-8 [12963926.001]
  • [Cites] Cancer. 2003 Oct 15;98(8):1716-26 [14534889.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 2003;10(3):250-2 [14605984.001]
  • [Cites] Arch Pathol Lab Med. 2004 Jan;128(1):95-8 [14692839.001]
  • [Cites] Am J Surg Pathol. 2004 Mar;28(3):298-307 [15104292.001]
  • [Cites] J Am Acad Dermatol. 2004 Jun;50(6):867-74 [15153886.001]
  • [Cites] Am J Surg. 1968 Oct;116(4):548-53 [5692131.001]
  • [Cites] JAMA. 1974 Oct 7;230(1):64-8 [4479235.001]
  • [Cites] Medicine (Baltimore). 1979 Jan;58(1):48-64 [368508.001]
  • [Cites] Cancer. 1981 Oct 15;48(8):1907-21 [7197190.001]
  • [Cites] Cancer. 1987 Mar 1;59(5):1046-57 [3815265.001]
  • [Cites] Cancer. 1988 Sep 15;62(6):1153-62 [2457426.001]
  • [Cites] Am J Med. 1992 Aug;93(2):219-22 [1497020.001]
  • [Cites] Arch Surg. 1991 Dec;126(12):1474-81 [1842176.001]
  • [Cites] Gastroenterol Clin Biol. 1995 Jun-Jul;19(6-7):625-8 [7590030.001]
  • [Cites] Cancer. 1996 Jun 1;77(11):2400-6 [8635113.001]
  • [Cites] Ann Surg Oncol. 2005 Dec;12(12):1090-101 [16252137.001]
  • (PMID = 16521200.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 30
  • [Other-IDs] NLM/ PMC4066137
  •  go-up   go-down


7. Lee SW, Song CY, Gi YH, Kang SB, Kim YS, Nam SW, Lee DS, Kim JO: Hepatic angiosarcoma manifested as recurrent hemoperitoneum. World J Gastroenterol; 2008 May 14;14(18):2935-8
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma manifested as recurrent hemoperitoneum.
  • Angiosarcoma is a rare tumor that account for less than 1% of all sarcomas.
  • Although hepatic angiosarcoma usually presents with unspecific symptoms, it rapidly progresses and has a high mortality.
  • We report a rare case of primary hepatic angiosarcoma manifested as recurrent hemoperitoneum.
  • [MeSH-major] Hemangiosarcoma / complications. Hemoperitoneum / diagnosis. Hemoperitoneum / etiology. Liver Neoplasms / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Surg. 1968 Oct;116(4):548-53 [5692131.001]
  • [Cites] Cancer. 1968 Aug;22(2):391-7 [4298242.001]
  • [Cites] Proc Natl Cancer Conf. 1972;7:89-900 [4358072.001]
  • [Cites] JAMA. 1975 May 12;232(6):625-8 [47404.001]
  • [Cites] Surg Clin North Am. 1977 Apr;57(2):339-60 [322336.001]
  • [Cites] Am J Pathol. 1978 Aug;92(2):349-76 [567014.001]
  • [Cites] Medicine (Baltimore). 1979 Jan;58(1):48-64 [368508.001]
  • [Cites] Lancet. 1979 Nov 24;2(8152):1120-3 [91848.001]
  • [Cites] Cancer. 1981 Feb 1;47(3):466-9 [6261909.001]
  • [Cites] Environ Health Perspect. 1981 Oct;41:107-13 [7199426.001]
  • [Cites] Arch Pathol Lab Med. 1985 Sep;109(9):853-7 [3927870.001]
  • [Cites] Cancer. 1991 Aug 1;68(3):463-73 [2065265.001]
  • [Cites] Clin Radiol. 1993 Nov;48(5):321-5 [8258223.001]
  • [Cites] Radiographics. 1994 Jan;14(1):153-66; quiz 167-8 [8128048.001]
  • [Cites] Cancer. 1995 Feb 15;75(4):989-96 [7842420.001]
  • [Cites] Diagn Cytopathol. 1998 Mar;18(3):208-11 [9523140.001]
  • [Cites] World J Gastroenterol. 2006 Feb 7;12(5):804-8 [16521200.001]
  • [Cites] JAMA. 1978 Sep 29;240(14):1510-11 [567256.001]
  • [Cites] AJR Am J Roentgenol. 2000 Jul;175(1):165-70 [10882268.001]
  • [Cites] Liver Transpl. 2000 Nov;6(6 Suppl 2):S23-9 [11084081.001]
  • [Cites] Am Surg. 2000 Dec;66(12):1153-7 [11149588.001]
  • [Cites] Hepatogastroenterology. 2000 Nov-Dec;47(36):1717-8 [11149040.001]
  • [Cites] Dig Dis Sci. 2003 Apr;48(4):677-82 [12741455.001]
  • [Cites] Cancer. 2003 Oct 15;98(8):1716-26 [14534889.001]
  • [Cites] Br Med J. 1971 Nov 13;4(5784):408-11 [5124443.001]
  • (PMID = 18473427.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2710744
  •  go-up   go-down


8. Mejía AF, Gierbolini L, Jacob B, Westmoreland SV: Pediatric hepatic hemangiosarcoma in a rhesus macaque (Macaca mulatta). J Med Primatol; 2009 Apr;38(2):121-4
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric hepatic hemangiosarcoma in a rhesus macaque (Macaca mulatta).
  • BACKGROUND: Pediatric hepatic angiosarcoma is a rare condition in children with poor prognosis.
  • Microscopically this neoplasm has a particular 'Kaposi-form' arrangement.
  • Hemangiosarcoma in non-human primates is a rare finding.
  • Immunohistochemistry was used to characterize the hepatic hemangiosarcoma.
  • RESULTS: The gross necropsy revealed hemoabdomen and a 4 x 3 x 3 cm mass in the liver with multiple smaller masses throughout the hepatic parenchyma.
  • Histopathology confirmed a poorly differentiated hemangiosarcoma.
  • CONCLUSIONS: Hemangiosarcoma in non-human primates has been rarely reported.
  • Diagnosis was confirmed by expression of endothelial-specific markers CD31 and vWF by immunohistochemistry.
  • Due to the young age of this monkey and the particular solid pattern throughout the mass this neoplasm resembles pediatric hepatic angiosarcoma in humans.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Med Primatol. 2001 Apr;30(2):127-30 [11491406.001]
  • [Cites] Neth J Med. 2007 Sep;65(8):279-82 [17890786.001]
  • [Cites] Diagn Mol Pathol. 2002 Sep;11(3):146-51 [12218453.001]
  • [Cites] Hum Pathol. 2002 Sep;33(9):884-92 [12378512.001]
  • [Cites] Pathol Vet. 1968;5(4):327-32 [5750002.001]
  • [Cites] Cancer Res. 1992 Feb 15;52(4):1044-6 [1310637.001]
  • [Cites] Lab Anim Sci. 1993 Jun;43(3):252-4 [8355487.001]
  • [Cites] J Med Primatol. 1993 Sep-Oct;22(7-8):431-2 [8169946.001]
  • [Cites] Pediatr Dev Pathol. 2004 Sep-Oct;7(5):527-32 [15547777.001]
  • [Cites] Pathology. 2005 Aug;37(4):284-7 [16194826.001]
  • [Cites] Vet Clin North Am Exot Anim Pract. 2006 Sep;9(3):689-94 [16931391.001]
  • [Cites] Vet Pathol. 2006 Nov;43(6):971-80 [17099154.001]
  • [Cites] Cardiovasc Pathol. 2006 Nov-Dec;15(6):303-17 [17113009.001]
  • [Cites] Arch Pathol Lab Med. 2007 Apr;131(4):538-44 [17425381.001]
  • [Cites] Pediatr Radiol. 2001 Aug;31(8):533-45 [11550763.001]
  • (PMID = 18671765.001).
  • [ISSN] 1600-0684
  • [Journal-full-title] Journal of medical primatology
  • [ISO-abbreviation] J. Med. Primatol.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / T32 RR007000; United States / NCRR NIH HHS / RR / U42 RR016021; United States / NCRR NIH HHS / RR / P51 RR000168; United States / NCRR NIH HHS / RR / P40 RR003640; United States / NCRR NIH HHS / RR / 2 P40RR003640; United States / NCRR NIH HHS / RR / T32 RR007000-32; United States / NCRR NIH HHS / RR / RR007000-32
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Denmark
  • [Other-IDs] NLM/ NIHMS93255; NLM/ PMC2664403
  •  go-up   go-down


9. Mekinian A, Lambert M, Queyrel V, Launay D, Morell-Dubois S, Hachulla E, Mathurin P, Hatron PY: [Adult-onset Still's disease and hepatic angiosarcoma, a fortuitous association or a paraneoplastic syndrome: a case-report]. Rev Med Interne; 2008 Nov;29(11):936-9
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adult-onset Still's disease and hepatic angiosarcoma, a fortuitous association or a paraneoplastic syndrome: a case-report].
  • [Transliterated title] Maladie de Still de l'adulte et angiosarcome hépatique, une association fortuite ou un syndrome paranéoplasique: à propos d'un cas.
  • Adult-onset Still's disease is a systemic disorder without specific histological feature.
  • Diagnosis requires to rule out any other disorder including neoplasia.
  • We report a patient with an adult-onset Still's disease who presented with a liver involvement at onset.
  • Two years later, a liver angiosarcoma was diagnosed.
  • This report underlines the difficulty of the diagnosis of the adult-onset Still's disease even in the presence of Yamaguchi et al.
  • 's [Medicine 81 (2002) 194-200] classification criteria and may suggest a link between the initial clinical picture and the discovery nearly two years later, of a liver angiosarcoma.

  • Genetic Alliance. consumer health - Still's disease adult onset.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18572281.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


10. Zhou YM, Li B, Yin ZM, Xu F, Wang B, Xu W, Liu P, Yang JM: Results of hepatic resection for primary hepatic angiosarcoma in adults. Med Sci Monit; 2010 Feb;16(2):CR61-6
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Results of hepatic resection for primary hepatic angiosarcoma in adults.
  • BACKGROUND: Primary hepatic angiosarcoma is an uncommon but aggressive malignancy with poor prognosis.
  • MATERIAL/METHODS: Medical records of 6 patients who underwent surgical resection for primary hepatic angiosarcoma at our institution between 1998 and 2006 were reviewed retrospectively.
  • The most common symptoms at diagnosis were pain in the right upper quadrant, abdominal distension, weakness and weight loss.
  • CONCLUSIONS: Although the overall outcome of surgical resection remains unsatisfactory, complete surgical resection may prolong survival of patients with solitary primary hepatic angiosarcoma without spontaneous rupture.
  • [MeSH-major] Hemangiosarcoma / surgery. Liver Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20110916.001).
  • [ISSN] 1643-3750
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


11. Park YS, Kim JH, Kim KW, Lee IS, Yoon HK, Ko GY, Sung KB: Primary hepatic angiosarcoma: imaging findings and palliative treatment with transcatheter arterial chemoembolization or embolization. Clin Radiol; 2009 Aug;64(8):779-85
Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary hepatic angiosarcoma: imaging findings and palliative treatment with transcatheter arterial chemoembolization or embolization.
  • AIM: To describe the image findings and results of transcatheter arterial chemoembolization (TACE) or transcatheter arterial embolization (TAE) for treating primary hepatic angiosarcoma.
  • MATERIALS AND METHODS: A retrospective review of the electronic medical database from 2002 to 2007, revealed six patients with primary hepatic angiosarcoma confirmed by percutaneous liver biopsy.
  • CONCLUSIONS: Primary hepatic angiosarcoma appears as a solitary or multiple, hypervascular lesions with heterogeneously early and progressive enhancement on CT and angiography.
  • Although TAE may be the primary procedure for achieving emergent bleeding control caused by the rupture of hepatic angiosarcomas, TACE may be effective for treating patients with a dominant hepatic angiosarcoma with or without intrahepatic metastases.
  • [MeSH-major] Hemangiosarcoma / radiography. Liver Neoplasms / radiography

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19589416.001).
  • [ISSN] 1365-229X
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; Q20Q21Q62J / Cisplatin
  •  go-up   go-down


12. Maluf D, Cotterell A, Clark B, Stravitz T, Kauffman HM, Fisher RA: Hepatic angiosarcoma and liver transplantation: case report and literature review. Transplant Proc; 2005 Jun;37(5):2195-9
MedlinePlus Health Information. consumer health - Liver Transplantation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma and liver transplantation: case report and literature review.
  • Hepatic angiosarcoma is a rare malignant vascular tumor that accounts for up to 2% of all primary liver tumors.
  • Accurate diagnosis of this tumor is difficult, especially if the patient has no history of exposure to specific carcinogens including thorotrast, arsenicals, and vinyl chloride monomer.
  • Diagnosis of diffuse angiosarcoma by means of liver biopsy has been reported as treacherous and nondiagnostic.
  • Herein, we present a case of a 61-year-old Caucasian male with history of cryptogenic cirrhosis, normal alpha-fetoprotein, and pretransplant abnormal liver MRI who underwent nondiagnostic liver biopsies followed by liver transplantation.
  • High grade diffuse angiosarcoma was diagnosed in the explanted liver.
  • Diffuse liver tissue infiltration seen pretransplant on CT scan or MRI, suggesting the possibility of diffuse liver lesions (HCC, angiosarcoma, etc) must be fully investigated with all techniques available including multiple open liver biopsies to avoid the sacrifice of a liver allograft in these patients.
  • [MeSH-major] Hemangiosarcoma / pathology. Hemangiosarcoma / surgery. Liver Neoplasms / pathology. Liver Neoplasms / surgery. Liver Transplantation

  • Genetic Alliance. consumer health - Transplantation.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15964377.001).
  • [ISSN] 0041-1345
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
  •  go-up   go-down


13. Arima-Iwasa S, Chijiiwa K, Makino I, Tanabe R, Ohuchida J, Kondo K: A case of hepatic angiosarcoma surviving for more than 16 months after hepatic resection. Hepatogastroenterology; 2007 Mar;54(74):533-5
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of hepatic angiosarcoma surviving for more than 16 months after hepatic resection.
  • Hepatic angiosarcoma is a non-epithelial malignant tumor and a rare primary neoplasm accounting for only a 0.1% of primary liver malignant tumors.
  • Hepatic angiosarcoma progresses rapidly; therefore, most cases are discovered at an advanced stage, and less than 20% of the patients have received surgery.
  • The lack of specific symptoms and radiological findings leads to the delay of diagnosis resulting in the poor prognosis.
  • To the best of our knowledge, only three patients have been reported to survive for more than one year after hepatic resection for angiosarcoma.
  • We herein report a patient with hepatic angiosarcoma, 4 cm in size, who underwent hepatic resection after confirming the diagnosis as angiosarcoma by the intraoperative frozen section examination.
  • [MeSH-major] Hemangiosarcoma / surgery. Hepatectomy. Liver Neoplasms / surgery
  • [MeSH-minor] Disease-Free Survival. Follow-Up Studies. Frozen Sections. Humans. Liver / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17523315.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


14. Darby C, Ntavlourou V: Hepatic hemangiosarcoma in two ferrets (Mustela putorius furo). Vet Clin North Am Exot Anim Pract; 2006 Sep;9(3):689-94
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic hemangiosarcoma in two ferrets (Mustela putorius furo).
  • One ferret was euthanized and necropsied, and one ferret underwent exploratory laparotomy and liver lobectomy.
  • In both cases, the histopathologic diagnosis was hepatic hemangiosarcoma.
  • [MeSH-major] Ferrets. Hemangiosarcoma / veterinary. Liver Neoplasms / veterinary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16931391.001).
  • [ISSN] 1094-9194
  • [Journal-full-title] The veterinary clinics of North America. Exotic animal practice
  • [ISO-abbreviation] Vet Clin North Am Exot Anim Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. Chiu O, Frank JD, Dow CA: Hepatic angiosarcoma: detection with computed tomography. Australas Radiol; 2005 Apr;49(2):163-5
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma: detection with computed tomography.
  • Hepatic angiosarcoma is a rare vascular neoplasm which occurs typically in men aged between 50 and 70 years.
  • A case of advanced multifocal hepatic angiosarcoma with splenic metastasis is presented with brief discussion of the clinical and histological features.
  • [MeSH-major] Hemangiosarcoma / radiography. Liver Neoplasms / radiography
  • [MeSH-minor] Aged. Diagnosis, Differential. Fatal Outcome. Humans. Male. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15845058.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


16. Ahmad Z, Nisa A, Idrees R, Minhas K, Pervez S, Mumtaz K: Hepatic angiosarcoma with metastasis to small intestine. J Coll Physicians Surg Pak; 2008 Jan;18(1):50-2
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma with metastasis to small intestine.
  • Hepatic angiosarcomas are rare tumours with poor prognosis, with patients usually dying within 6 months.
  • Similarly, primary or metastatic angiosarcomas in small intestine are extremely rare, often present with recurrent gastrointestinal bleeding and anemia, and have an extremely poor prognosis.
  • Both primary or metastatic intestinal angiosarcomas may exhibit epithelioid morphology.
  • It may be very difficult to differentiate between primary and secondary cases in intestine and especially when the tumour exhibits epithelioid morphology.
  • [MeSH-major] Hemangiosarcoma / pathology. Ileal Neoplasms / secondary. Intestine, Small / pathology. Jejunal Neoplasms / secondary. Liver Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Intestinal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18452671.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  •  go-up   go-down


17. Wang ZS, Wang WX, Xiong CL, Zhan N, Li H: Spontaneous ruptured primary hepatic angiosarcoma coincident with Schistosoma Japonica liver fibrosis. Hepatol Res; 2007 Jul;37(7):572-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous ruptured primary hepatic angiosarcoma coincident with Schistosoma Japonica liver fibrosis.
  • AIM: We report herein a case of spontaneous ruptured primary hepatic angiosarcoma coincident with Schistosoma Japonica liver fibrosis and review the correlative literature.
  • RESULTS: The final diagnosis was spontaneous ruptured primary hepatic angiosarcoma coincident with Schistosoma Japonica liver fibrosis Conclusion: Considering the nature of primary hepatic angiosarcoma, in particular the ruptured hepatic angiosarcoma, it is obviously desirable to avoid any unnecessary delay or definitive surgical treatment.
  • It is presumed that angiosarcoma in the liver has a possible association with S. japonicum and the deposition of ovae in liver.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17540001.001).
  • [ISSN] 1386-6346
  • [Journal-full-title] Hepatology research : the official journal of the Japan Society of Hepatology
  • [ISO-abbreviation] Hepatol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


18. Nord KM, Kandel J, Lefkowitch JH, Lobritto SJ, Morel KD, North PE, Garzon MC: Multiple cutaneous infantile hemangiomas associated with hepatic angiosarcoma: case report and review of the literature. Pediatrics; 2006 Sep;118(3):e907-13
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple cutaneous infantile hemangiomas associated with hepatic angiosarcoma: case report and review of the literature.
  • Multiple cutaneous hemangiomas can be associated with internal hemangiomas, with the liver being the most common site.
  • Here we report a case of a premature female neonate who presented with cardiac failure at birth and had typical-appearing infantile hemangiomas on the skin in association with vascular lesions in the liver.
  • Her clinical presentation was felt to be consistent with cutaneous and hepatic infantile hemangiomas.
  • After failure to respond to systemic steroids and chemotherapy, she underwent liver transplantation.
  • Histopathologic evaluation of the liver revealed a diagnosis of type 2 infantile hepatic hemangioendothelioma (regarded as synonymous with angiosarcoma) rather than benign infantile hemangioma of the liver.
  • Subsequent skin biopsies confirmed that her multiple cutaneous lesions were infantile hemangiomas and not metastatic angiosarcoma.
  • We report this case and a review of the literature on pediatric angiosarcoma of the liver associated with cutaneous infantile hemangiomas.
  • [MeSH-major] Hemangioma / pathology. Hemangiosarcoma / pathology. Liver Neoplasms / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Female. Heart Defects, Congenital. Humans. Infant, Newborn. Liver Transplantation

  • MedlinePlus Health Information. consumer health - Birthmarks.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Pediatrics. 2007 Jun;119(6):1271
  • (PMID = 16880251.001).
  • [ISSN] 1098-4275
  • [Journal-full-title] Pediatrics
  • [ISO-abbreviation] Pediatrics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
  •  go-up   go-down


19. Li Q, Wang J, Sun Y, Cui Y, Hao X: Hepatic angiosarcoma arising in an adult mesenchymal hamartoma. Int Semin Surg Oncol; 2007;4:3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma arising in an adult mesenchymal hamartoma.
  • The histogenesis of the hepatic sarcoma and its association with hamartoma is not well understood.
  • We hereby present a Chinese patient with hepatic angiosarcoma arising from an adult mesenchymal hamartoma of liver.
  • A 33-yr-old woman was diagnosed hepatic hamartoma eight years ago and presented with epigastric distention recently.
  • Now she was admitted to our hospital with some unusual features: (a) this patient was diagnosed in mid-twenties, (b) the tumor occupied the whole liver and most importantly (c) the hepatic angiosarcoma appeared 8 years after the diagnosis of hamartoma.
  • Based on this case and some reports, hepatic hamartoma may develop to hepatic angiosarcoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Mod Pathol. 1994 May;7(4):490-3 [8066077.001]
  • [Cites] Am J Surg Pathol. 1997 Oct;21(10):1248-54 [9331300.001]
  • [Cites] Radiographics. 1994 Jan;14(1):153-66; quiz 167-8 [8128048.001]
  • [Cites] Am J Ind Med. 1981;2(1):43-50 [6891179.001]
  • [Cites] Pediatr Pathol. 1983 Jul-Sep;1(3):245-67 [6687279.001]
  • [Cites] AJR Am J Roentgenol. 1986 May;146(5):997-1004 [3008544.001]
  • [Cites] Pediatr Dev Pathol. 2001 Sep-Oct;4(5):482-9 [11779051.001]
  • (PMID = 17257403.001).
  • [ISSN] 1477-7800
  • [Journal-full-title] International seminars in surgical oncology : ISSO
  • [ISO-abbreviation] Int Semin Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1796548
  •  go-up   go-down


20. Heo SH, Jeong YY, Shin SS, Chung TW, Kang HK: Solitary small hepatic angiosarcoma: initial and follow-up imaging findings. Korean J Radiol; 2007 Mar-Apr;8(2):180-3
Hazardous Substances Data Bank. GADOPENTETATE DIMEGLUMINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary small hepatic angiosarcoma: initial and follow-up imaging findings.
  • We report an uncommon case of solitary, small hepatic angiosarcoma that was initially considered as a hemangioma.
  • We present the imaging findings, with an emphasis on the initial and follow-up CT and MR findings, as well as report on the more suggestive findings of angiosarcoma than those of a hemangioma.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Contrast Media. Diagnosis, Differential. Gadolinium DTPA. Hemangioma / diagnosis. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] AJR Am J Roentgenol. 2000 Jul;175(1):165-70 [10882268.001]
  • [Cites] Hepatogastroenterology. 2000 Nov-Dec;47(36):1717-8 [11149040.001]
  • [Cites] Radiology. 2002 Mar;222(3):667-73 [11867783.001]
  • [Cites] Radiographics. 1994 Jan;14(1):153-66; quiz 167-8 [8128048.001]
  • [Cites] Br J Radiol. 2003 Dec;76(912):866-74 [14711773.001]
  • [Cites] J Comput Assist Tomogr. 1989 Sep-Oct;13(5):910-2 [2778153.001]
  • [Cites] AJR Am J Roentgenol. 1992 Mar;158(3):535-9 [1738990.001]
  • [Cites] Abdom Imaging. 2002 Nov-Dec;27(6):690-9 [12395258.001]
  • (PMID = 17420638.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
  • [Other-IDs] NLM/ PMC2626776
  •  go-up   go-down


21. Tate G, Suzuki T, Mitsuya T: Mutation of the PTEN gene in a human hepatic angiosarcoma. Cancer Genet Cytogenet; 2007 Oct 15;178(2):160-2
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mutation of the PTEN gene in a human hepatic angiosarcoma.
  • The PTEN protein inhibits angiogenesis, and somatic mutations of the PTEN gene are involved in canine hemangiosarcoma.
  • We screened for mutations of the PTEN gene in two patients with human hepatic angiosarcoma to determine whether PTEN is involved in the pathogenesis of human hepatic angiosarcoma.
  • In one patient, who suffered from breast cancer, pharyngeal cancer, and hepatic angiosarcoma, we found a single base substitution in exon 7 (640C>T) of the PTEN gene in both the hepatic angiosarcoma and normal tissues.
  • These findings indicate that analysis of PTEN gene mutations may be useful for characterization of the molecular event in hepatic angiosarcoma and cancer predisposition.
  • [MeSH-major] Hemangiosarcoma / genetics. Liver Neoplasms / genetics. Mutation. PTEN Phosphohydrolase / genetics

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17954274.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
  •  go-up   go-down


22. Kulkarni MP, Agashe SR, Singh RV, Sulhyan KR: Hepatic angiosarcoma arising in an adult mesenchymal hamartoma. Indian J Pathol Microbiol; 2010 Apr-Jun;53(2):322-4
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma arising in an adult mesenchymal hamartoma.
  • Embryonal (undifferentiated) sarcomas arising in mesenchymal hamartoma are on record but cases of hepatic angiosarcoma (AS) arising in mesenchymal hamartoma (MH) of the liver are extremely rare.
  • Ultrasonography (USG) revealed a well circumscribed mass on the undersurface of the right lobe of liver suggestive of hemangioma.
  • [MeSH-major] Hamartoma / complications. Hamartoma / diagnosis. Hemangiosarcoma / diagnosis. Hemangiosarcoma / pathology. Liver Neoplasms / diagnosis. Liver Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20551545.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] India
  •  go-up   go-down


23. Oe A, Habu D, Kawabe J, Torii K, Kawamura E, Kotani J, Hayashi T, Sakaguchi H, Shiomi S: A case of diffuse hepatic angiosarcoma diagnosed by FDG-PET. Ann Nucl Med; 2005 Sep;19(6):519-21
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of diffuse hepatic angiosarcoma diagnosed by FDG-PET.
  • Fluorine-18 2-deoxy-2-fluoro-D-glucose (FDG)-positron emission tomography (PET) showed diffuse abnormal accumulation throughout the entire liver.
  • She was diagnosed by histopathological examination as having hepatic angiosarcoma causing veno-occlusive disease (VOD).
  • This is the first report of hepatic angiosarcoma with FDG-PET.
  • [MeSH-major] Fluorodeoxyglucose F18. Hemangiosarcoma / complications. Hemangiosarcoma / radionuclide imaging. Hepatic Veno-Occlusive Disease / etiology. Hepatic Veno-Occlusive Disease / radionuclide imaging. Liver Neoplasms / complications. Liver Neoplasms / radionuclide imaging

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16248391.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  •  go-up   go-down


24. Cioffi-Pretti JL, Kalof AN, Ebert G, McCahill LE: Hepatic angiosarcoma five years following spontaneous intraperitoneal bleed of a hepatic mass. Rare Tumors; 2009;1(2):e33
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma five years following spontaneous intraperitoneal bleed of a hepatic mass.
  • Primary hepatic angiosarcoma is a rare and rapidly fatal disease.
  • A CT scan showed a hepatic mass with intralesional hemorrhage, intraperitoneal blood, and splenomegaly.
  • Contralateral lobe biopsies revealed normal liver tissue.
  • A repeat biopsy demonstrated a neoplasm of vascular etiology and uncertain malignant potential.
  • By early 2008 the lesion had increased to 4.8 cm and was resected via a left hepatic lobectomy.
  • An extremely vascular lesion with surrounding dense fibrosis was identified and pathologic examination demonstrated a high-grade angiosarcoma.We are unaware of any previous reports suggesting such a prolonged natural history of hepatic angiosarcoma.
  • This case may represent the possibility of malignant transformation of a lower grade vascular neoplasm such as hepatic epithelioid hemangioendothelioma to an angiosarcoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21139912.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994458
  • [Keywords] NOTNLM ; hepatic angiosarcoma / hepatic mass / spontaneous intraperitoneal bleed.
  •  go-up   go-down


25. Infante PF, Petty SE, Groth DH, Markowitz G, Rosner D: Vinyl chloride propellant in hair spray and angiosarcoma of the liver among hairdressers and barbers: case reports. Int J Occup Environ Health; 2009 Jan-Mar;15(1):36-42
Hazardous Substances Data Bank. VINYL CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vinyl chloride propellant in hair spray and angiosarcoma of the liver among hairdressers and barbers: case reports.
  • Two cases of angiosarcoma of the liver (ASL) are, to the best of our knowledge, the first literature reports of such cases identified among hairdressers and barbers who used hair sprays containing vinyl chloride (VC) as a propellant.
  • As ASL is a sentinel cancer for exposure to VC, identification of these cases raises concern about the contribution of VC to hepatocellular carcinoma (HCC), a much more common type of liver cancer, as well as other VC-related cancers among hairdressers and barbers.
  • [MeSH-major] Aerosol Propellants / poisoning. Beauty Culture. Cosmetics / poisoning. Hemangiosarcoma / chemically induced. Liver Neoplasms / chemically induced. Occupational Diseases / chemically induced. Vinyl Chloride / poisoning

  • MedlinePlus Health Information. consumer health - Cosmetics.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • MedlinePlus Health Information. consumer health - Occupational Health.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19267125.001).
  • [ISSN] 1077-3525
  • [Journal-full-title] International journal of occupational and environmental health
  • [ISO-abbreviation] Int J Occup Environ Health
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aerosol Propellants; 0 / Cosmetics; WD06X94M2D / Vinyl Chloride
  • [Number-of-references] 59
  •  go-up   go-down


26. Stambo GW, Guiney MJ: Hepatic angiosarcoma presenting as an acute intraabdominal hemorrhage treated with transarterial chemoembolization. Sarcoma; 2007;2007:90169

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma presenting as an acute intraabdominal hemorrhage treated with transarterial chemoembolization.
  • Primary malignant neoplasms of the liver are some of the most uncommon malignancies in many parts of the world.
  • They include hepatocellular carcinoma and stromal tumors such as hepatic angiosarcoma.
  • Like other vascular tumors of the liver and spleen, intraperitoneal hemorrhage is a well-documented finding of angiosarcoma which can be lethal if not diagnosed and treated immediately.
  • As in our case, intraperitoneal hemorrhage from primary tumor rupture was the only clinical presentation of this neoplasm.
  • Although several therapeutic options are available, we describe apalliative therapy for hepatic angiosarcoma utilizing transcatheter arterial chemoembolization (TACE) techniques incorporating the newer embolization agent Embospheres to locally target and treat this aggressive tumor.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Pathol. 1974 Jan;97(1):39-42 [4808442.001]
  • [Cites] Arch Surg. 2002 Apr;137(4):422-6; discussion 427 [11926946.001]
  • [Cites] J Vasc Interv Radiol. 2002 Oct;13(10):991-4 [12397119.001]
  • [Cites] Curr Oncol Rep. 2002 Nov;4(6):515-9 [12354365.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 2003;10(3):250-2 [14605984.001]
  • [Cites] J Vasc Interv Radiol. 2004 Apr;15(4):335-45 [15064336.001]
  • [Cites] Vopr Onkol. 1988;34(6):744-6 [2455945.001]
  • [Cites] Curr Treat Options Oncol. 2001 Dec;2(6):485-91 [12057094.001]
  • [Cites] Dig Dis Sci. 2003 Apr;48(4):677-82 [12741455.001]
  • [Cites] Radiographics. 2002 Sep-Oct;22(5):1077-91 [12235337.001]
  • [Cites] Am Surg. 2000 Dec;66(12):1153-7 [11149588.001]
  • [Cites] Clin Liver Dis. 2001 Feb;5(1):219-57, viii [11218917.001]
  • [Cites] Radiology. 2002 Mar;222(3):667-73 [11867783.001]
  • (PMID = 18288242.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2225468
  •  go-up   go-down


27. Kim HR, Rha SY, Cheon SH, Roh JK, Park YN, Yoo NC: Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma. Ann Oncol; 2009 Apr;20(4):780-7
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma.
  • BACKGROUND: Primary hepatic angiosarcoma is a very rare malignancy with a poor prognosis.
  • PATIENTS AND METHODS: Among 11,939 patients diagnosed with primary hepatic tumors from January 1985 to December 2007 at two centers, five patients were diagnosed with primary hepatic angiosarcoma.
  • Two of four patients who received chemotherapy died <3 months after diagnosis, but the other two patients survived >6 months.
  • This case study may aid in planning chemotherapy for patients with advanced hepatic angiosarcoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19179547.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


28. Premalata CS, Kumar RV, Appaji L, Prabhakaran PS: Childhood hepatic angiosarcoma--a case report. Indian J Pathol Microbiol; 2005 Oct;48(4):487-9
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Childhood hepatic angiosarcoma--a case report.
  • Hepatic angiosarcoma (HAS) is an extremely rare liver tumor in children.
  • Left hepatic lobectomy was performed with a clinical diagnosis of hepatoblastoma.
  • Histopathological examination revealed features typical of hepatic angiosarcoma.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Liver Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16366104.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


29. Matthaei H, Boelke E, Eisenberger CF, Alldinger I, Krieg A, Schmelzle M, Poremba C, Schellhammer F, Knoefel WT, Budach W, Peiper M: Interdisciplinary treatment of primary hepatic angiosarcoma: emergency tumor embolization followed by elective surgery. Eur J Med Res; 2007 Dec 14;12(12):591-4
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Interdisciplinary treatment of primary hepatic angiosarcoma: emergency tumor embolization followed by elective surgery.
  • Among primary hepatic malignancies, sarcomas represent a minority of 2 %.
  • Of those, primary hepatic angiosarcoma is the most common one.
  • - We herein report the successful interdisciplinary treatment of an 81 year-old woman with a perforated primary hepatic angiosarcoma of the left hepatic lobe.
  • - So far, no standard therapy has established for patients with primary hepatic angiosarcoma.
  • - The outcome of most patients with primary hepatic angiosarcoma remains poor and there is a need for clinical studies.
  • [MeSH-major] Embolization, Therapeutic. Hemangiosarcoma / therapy. Liver Neoplasms / therapy

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18024270.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


30. Kahraman A, Miller M, Baba H, Gerken G, Hilgard P: [Angiosarcoma of the liver as a rare cause of rapidly progressive liver failure]. Med Klin (Munich); 2006 Sep 15;101(9):746-50
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiosarcoma of the liver as a rare cause of rapidly progressive liver failure].
  • [Transliterated title] Angiosarkom der Leber als seltene Ursache eines rasch progredienten Leberversagens.
  • BACKGROUND: Angiosarcoma of the liver is a rare, highly malignant and sometimes diffusely infiltrating vessel tumor with rapid progression and poor prognosis.
  • CASE REPORT: A 46-year-old male patient with rapidly progressive liver failure, initially regarded as decompensation of known alcoholic liver cirrhosis, is reported.
  • The patient was referred to the authors' center for evaluation of liver transplantation, but a massive weight loss despite long absence of any alcohol intake raised the suspicion of a malignant disease.
  • A following MRI demonstrated diffuse focal contrast enhancement in the entire liver parenchyma, confirming diffuse infiltration of the organ by a malignant tumor.
  • Sonographically guided percutaneous liver biopsy established the diagnosis of a malignant vascular tumor with diffuse infiltration of the liver parenchyma.
  • Macroscopic examination of the liver during autopsy showed multiple lacunae filled with blood.
  • Therefore, the differential diagnosis of a peliosis hepatis was raised.
  • However, histology confirmed the diagnosis of a malignant angiosarcoma with diffuse osseous metastases.
  • CONCLUSION: A diffuse infiltration of the liver by an angiosarcoma in the absence of any definite lesions may lead to a substantial delay of the diagnosis.
  • The only relevant differential diagnosis in this case is the equally rare peliosis hepatis.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Liver Failure / etiology. Liver Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Bone Neoplasms / secondary. Diagnosis, Differential. Disease Progression. Esophageal and Gastric Varices / pathology. Fatal Outcome. Gastrointestinal Hemorrhage / pathology. Humans. Liver / pathology. Liver Cirrhosis, Alcoholic / diagnosis. Liver Cirrhosis, Alcoholic / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Peliosis Hepatis / diagnosis. Peliosis Hepatis / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16977400.001).
  • [ISSN] 0723-5003
  • [Journal-full-title] Medizinische Klinik (Munich, Germany : 1983)
  • [ISO-abbreviation] Med. Klin. (Munich)
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


31. Le Scanff J, Durupt S, Bailly F, Rode A, Sève P: A strange Evans syndrome: a case report. Cases J; 2009;2:8001

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hepatic angiosarcoma is a rare malignant vascular tumor, which accounts for up to 2% of all primary liver tumors.
  • Diagnosis of diffuse hepatic angiosarcoma can be challenging.
  • We report an original case of diffuse liver angiosarcoma revealed by haematological abnormalities initially diagnosed as an Evans syndrome.
  • Diagnosis of diffuse liver angiosarcoma can be extremely difficult and physicians should be aware of these presentation.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Medicina (B Aires). 1997;57(5):587-90 [9674228.001]
  • [Cites] Cancer. 2007 Apr 1;109(7):1391-6 [17315167.001]
  • [Cites] Dig Dis Sci. 2003 Apr;48(4):677-82 [12741455.001]
  • [Cites] Radiology. 2002 Mar;222(3):667-73 [11867783.001]
  • (PMID = 19830043.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2740225
  •  go-up   go-down


32. Oztürk E, Mutlu H, Sönmez G, Sildiroğlu HO: Primary angiosarcoma of the spleen. Turk J Gastroenterol; 2007 Dec;18(4):272-5
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the spleen.
  • Primary angiosarcoma of the spleen is a rare neoplasm with a very poor prognosis.
  • We present computed tomography and magnetic resonance imaging of a 49-year-old man with primary splenic angiosarcoma and liver metastasis.
  • The literature on primary splenic angiosarcoma is reviewed and imaging variability of this rare tumor is discussed.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Splenic Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18080928.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 23
  •  go-up   go-down


33. Hadidy A, Alsharif A, Sheikh-Ali R, Abukhalaf M, Awidi A, Abukaraki A, Nimri C, Omari A: Odontogenic myxofibroma synchronous with primary angiosarcoma of the spleen. Br J Radiol; 2010 Jan;83(985):e10-3
MedlinePlus Health Information. consumer health - Temporomandibular Joint Dysfunction.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Odontogenic myxofibroma synchronous with primary angiosarcoma of the spleen.
  • Odontogenic myxofibroma of the temporomandibular joint (TMJ) is a rare tumour; moreover, primary splenic angiosarcoma (PAS) in paediatric patients is extremely rare.
  • The TMJ swelling proved to be odontogenic myxofibroma and the abdominal pain was a result of primary splenic angiosarcoma with hepatic metastasis.
  • We report for the first time the synchronous presentation of PAS and odontogenic myxofibroma in a paediatric patient, and we describe the radiological features along with the histological diagnosis and clinical outcome.
  • [MeSH-major] Fibroma / diagnosis. Hemangiosarcoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Odontogenic Tumors / diagnosis. Splenic Neoplasms / diagnosis. Temporomandibular Joint Disorders / diagnosis
  • [MeSH-minor] Adolescent. Bone Neoplasms / secondary. Diagnosis, Differential. Fatal Outcome. Humans. Liver Neoplasms / secondary. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Abdom Imaging. 2000 May-Jun;25(3):283-5 [10823452.001]
  • [Cites] Radiographics. 2004 Jul-Aug;24(4):1137-63 [15256634.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 2004 Oct;68(10):1251-6 [15364495.001]
  • [Cites] Radiology. 2005 Apr;235(1):106-15 [15749977.001]
  • [Cites] Pediatr Surg Int. 2007 Aug;23(8):807-10 [17641924.001]
  • [Cites] J Nucl Med. 2006 May;47(5):885-95 [16644760.001]
  • [Cites] AJR Am J Roentgenol. 2006 Oct;187(4):1124-8 [16985165.001]
  • [Cites] AJR Am J Roentgenol. 2007 Jun;188(6):1615-7 [17515384.001]
  • [Cites] Pediatr Hematol Oncol. 2005 Jul-Aug;22(5):387-90 [16020128.001]
  • (PMID = 20139242.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3487256
  •  go-up   go-down


34. Suzuki H, Komatsu A, Fujioka Y, Yamashiro K, Takeda H, Hamada T: Angiosarcoma-like metastatic carcinoma of the liver. Pathol Res Pract; 2010 Jul 15;206(7):484-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma-like metastatic carcinoma of the liver.
  • Two cases of metastatic carcinoma strikingly simulating angiosarcoma in the liver are described.
  • The first case was a 53-year-old female with cystic liver tumors which were found 22 months after surgery for ureteral cancer.
  • The second case was an 81-year-old female with multiple tumors in the liver and the pancreas, and a post-mortem examination was carried out.
  • Both cases had an angiosarcoma-like appearance macroscopically and microscopically.
  • Immunohistochemically, the tumor cells of both cases were negative for CD31, CD34, and Factor VIII-related antigen and positive for several types of cytokeratin, suggesting that they were not angiosarcomas but carcinomas.
  • Angiosarcoma is the most common sarcoma arising in the liver.
  • Thus, metastatic carcinoma, which resembles angiosarcoma, might be mistaken for angiosarcoma.
  • [MeSH-major] Carcinoma / secondary. Liver Neoplasms / secondary. Skin Neoplasms / pathology. Ureteral Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Hemangiosarcoma / pathology. Humans. Immunohistochemistry. Middle Aged

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 Elsevier GmbH. All rights reserved.
  • (PMID = 20097483.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


35. Ikeda K, Maehara M, Ohmura N, Kurokawa H, Koda K, Yokoyama H, Sawada S: Spontaneous rupture of a necrotic hepatic angiosarcoma: findings on dual-phase computed tomography and angiography. Radiat Med; 2006 Jun;24(5):369-72
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous rupture of a necrotic hepatic angiosarcoma: findings on dual-phase computed tomography and angiography.
  • We present dual-phase computed tomographic (CT) and angiographic findings of a ruptured hepatic angiosarcoma.
  • We found that dual-phase CT and angiographic findings are able to distinguish angiosarcoma, which mimics a hemangioma, as these lesions show avascular areas that reflect a mass with gross central necrosis.
  • [MeSH-major] Hemangiosarcoma / diagnostic imaging. Liver Neoplasms / diagnostic imaging. Tomography, X-Ray Computed / methods

  • MedlinePlus Health Information. consumer health - CT Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Q J Med. 1984 Summer;53(211):391-400 [6207557.001]
  • [Cites] Clin Radiol. 1993 Nov;48(5):321-5 [8258223.001]
  • [Cites] J Comput Assist Tomogr. 1989 Sep-Oct;13(5):910-2 [2778153.001]
  • [Cites] AJR Am J Roentgenol. 1982 May;138(5):965-6 [6979189.001]
  • [Cites] AJR Am J Roentgenol. 2000 Jul;175(1):165-70 [10882268.001]
  • [Cites] Medicine (Baltimore). 1979 Jan;58(1):48-64 [368508.001]
  • [Cites] J Comput Assist Tomogr. 1983 Oct;7(5):899-901 [6684129.001]
  • [Cites] Eur Radiol. 2000;10(1):129-33 [10663729.001]
  • [Cites] Radiology. 2002 Mar;222(3):667-73 [11867783.001]
  • [Cites] Environ Health Perspect. 1981 Oct;41:107-13 [7199426.001]
  • [Cites] Radiology. 1989 May;171(2):343-7 [2539607.001]
  • (PMID = 16958416.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


36. Sherman M: Vinyl chloride and the liver. J Hepatol; 2009 Dec;51(6):1074-81
Hazardous Substances Data Bank. VINYL CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vinyl chloride and the liver.
  • Vinyl chloride monomer is a known cause of angiosarcoma of the liver.
  • It also has other toxic effects on the liver, and it has recently been suggested that exposure to vinyl chloride also causes hepatocellular carcinoma.
  • In the largest studies lack of data meant that confounding diseases such as viral hepatitis or alcoholic liver disease could not be assessed.
  • [MeSH-major] Liver / drug effects. Vinyl Chloride / toxicity
  • [MeSH-minor] Animals. Carcinoma, Hepatocellular / chemically induced. Hemangiosarcoma / chemically induced. Humans. Liver Cirrhosis / chemically induced. Liver Neoplasms / chemically induced. Mutagens / toxicity. Occupational Exposure. Risk Factors

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19836850.001).
  • [ISSN] 1600-0641
  • [Journal-full-title] Journal of hepatology
  • [ISO-abbreviation] J. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Mutagens; WD06X94M2D / Vinyl Chloride
  • [Number-of-references] 50
  •  go-up   go-down


37. Verge J, Albiol J, Navas M, Martín C: [Primary angiosarcoma of the spleen with liver metastases. Case report and literature review]. Cir Esp; 2005 Jul;78(1):50-2
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary angiosarcoma of the spleen with liver metastases. Case report and literature review].
  • [Transliterated title] Angiosarcoma primario de bazo con metástasis hepáticas: presentación de un caso y revisión de la bibliografía.
  • Angiosarcomas of the spleen are infrequent tumors that often present with liver metastases.
  • Immunohistochemical markers can aid preoperative diagnosis since radiological and ultrasonographic images are fairly nonspecific.
  • [MeSH-major] Hemangiosarcoma / secondary. Hemangiosarcoma / surgery. Liver Neoplasms / secondary. Liver Neoplasms / surgery. Splenic Neoplasms / pathology. Splenic Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16420791.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


38. Hamid KS, Rodriguez JA, Lairmore TC: Primary splenic angiosarcoma. JSLS; 2010 Jul-Sep;14(3):431-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary splenic angiosarcoma.
  • Primary splenic angiosarcoma is a rare, aggressive malignant neoplasm arising from splenic vascular endothelium.
  • Laparoscopic splenectomy was performed, and a primary splenic angiosarcoma was discovered.
  • After 2 rounds of chemotherapy, a CT scan showed progressive disease with metastasis to the liver and lung.
  • Primary splenic angiosarcoma is almost universally fatal despite treatment.
  • The best chance for survival is early diagnosis and prompt splenectomy prior to splenic rupture.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Mod Pathol. 2000 Sep;13(9):978-87 [11007038.001]
  • [Cites] Med Pediatr Oncol. 2003 Jun;40(6):411-2 [12692821.001]
  • [Cites] Radiographics. 2004 Jul-Aug;24(4):1137-63 [15256634.001]
  • [Cites] Int Surg. 1980 Jul-Aug;65(4):369-73 [7194868.001]
  • [Cites] Med Pediatr Oncol. 1981;9(4):319-24 [7196486.001]
  • [Cites] Cancer. 1985 Apr 1;55(7):1625-7 [4038910.001]
  • [Cites] Am J Surg Pathol. 1993 Oct;17(10):959-70 [8372948.001]
  • [Cites] Acta Pathol Jpn. 1993 Nov;43(11):702-8 [8310831.001]
  • [Cites] South Med J. 1995 Aug;88(8):873-5 [7631220.001]
  • [Cites] J Surg Oncol. 1996 Mar;61(3):170-6 [8637202.001]
  • [Cites] Cancer. 1996 Jun 1;77(11):2400-6 [8635113.001]
  • [Cites] Am J Surg Pathol. 1997 Jul;21(7):827-35 [9236839.001]
  • [Cites] Radiology. 2005 Apr;235(1):106-15 [15749977.001]
  • [Cites] Pediatr Surg Int. 2007 Aug;23(8):807-10 [17641924.001]
  • [Cites] J Natl Med Assoc. 2000 Mar;92(3):143-6 [10745645.001]
  • (PMID = 21333203.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3041046
  •  go-up   go-down


39. Liu J, Waalkes MP: Liver is a target of arsenic carcinogenesis. Toxicol Sci; 2008 Sep;105(1):24-32
Hazardous Substances Data Bank. ARSENIC, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver is a target of arsenic carcinogenesis.
  • Inorganic arsenic is clearly a human carcinogen causing tumors of the skin, lung, urinary bladder, and possibly liver (IARC, 2004).
  • This forum reevaluates epidemiology studies, rodent studies together with in vitro models, and focuses on the liver as a target organ of arsenic toxicity and carcinogenesis.
  • Hepatocellular carcinoma and hepatic angiosarcoma, have been frequently associated with environmental or medicinal exposure to arsenicals.
  • In rats, the methylated arsenicals, dimethylarsinic acid promotes diethylnitrosamine-initiated liver tumors, whereas trimethylarsine oxide induces liver adenomas.
  • Chronic exposure of rat liver epithelial cells to low concentrations of inorganic arsenic induces malignant transformation, producing aggressive, undifferentiated epithelial tumors when inoculated into the Nude mice.
  • Some of these mechanisms may be liver specific/selective.
  • Overall, accumulating evidence clearly indicates that the liver could be an important target of arsenic carcinogenesis.

  • MedlinePlus Health Information. consumer health - Arsenic.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Carcinogenesis. 2004 Jan;25(1):133-41 [14514661.001]
  • [Cites] Toxicol Sci. 2004 Feb;77(2):249-57 [14691202.001]
  • [Cites] Int J Clin Pharmacol Res. 1988;8(2):117-22 [3378853.001]
  • [Cites] Am J Epidemiol. 1989 Dec;130(6):1123-32 [2589305.001]
  • [Cites] Cancer Res. 1990 Sep 1;50(17):5470-4 [2386951.001]
  • [Cites] Toxicol Appl Pharmacol. 2004 Aug 1;198(3):366-76 [15276416.001]
  • [Cites] Carcinogenesis. 2004 Sep;25(9):1779-86 [15073043.001]
  • [Cites] Environ Health Perspect. 2004 Aug;112(12):1255-63 [15345372.001]
  • [Cites] J Toxicol Environ Health A. 2004 Oct 8;67(19):1491-500 [15371225.001]
  • [Cites] Gut. 1979 May;20(5):378-84 [468068.001]
  • [Cites] J Hepatol. 1990 Jul;11(1):80-5 [2398270.001]
  • [Cites] Carcinogenesis. 2004 Mar;25(3):413-7 [14633664.001]
  • [Cites] J Natl Cancer Inst. 2004 Mar 17;96(6):466-74 [15026472.001]
  • [Cites] Toxicol Lett. 1983 Feb;15(2-3):105-8 [6829033.001]
  • [Cites] Arch Toxicol. 1984 Sep;55(3):151-4 [6497648.001]
  • [Cites] Cancer Res. 1985 Nov;45(11 Pt 2):5895-9 [4053060.001]
  • [Cites] Br J Cancer. 1986 Mar;53(3):399-405 [3964542.001]
  • [Cites] Lancet. 1988 Feb 20;1(8582):414-5 [2893213.001]
  • [Cites] Environ Health Perspect. 1992 Jul;97:259-67 [1396465.001]
  • [Cites] Br J Cancer. 1992 Nov;66(5):888-92 [1419632.001]
  • [Cites] Am J Epidemiol. 1995 Feb 1;141(3):198-209 [7840093.001]
  • [Cites] Cancer Res. 1995 Mar 15;55(6):1271-6 [7882321.001]
  • [Cites] Zhonghua Liu Xing Bing Xue Za Zhi. 1995 Oct;16(5):289-91 [8706097.001]
  • [Cites] Mutat Res. 1997 Jun;386(3):263-77 [9219564.001]
  • [Cites] Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10907-12 [9380733.001]
  • [Cites] Am J Epidemiol. 1998 Apr 1;147(7):660-9 [9554605.001]
  • [Cites] Int J Epidemiol. 1998 Aug;27(4):561-9 [9758107.001]
  • [Cites] Environ Health Perspect. 1999 May;107(5):359-65 [10210691.001]
  • [Cites] Arch Environ Health. 1999 May-Jun;54(3):186-93 [10444040.001]
  • [Cites] IARC Monogr Eval Carcinog Risks Hum. 2004;84:269-477 [15645578.001]
  • [Cites] Toxicol Appl Pharmacol. 2005 Aug 7;206(2):169-75 [15967205.001]
  • [Cites] Cancer Res. 2006 Feb 1;66(3):1337-45 [16452187.001]
  • [Cites] Environ Health Perspect. 2006 Mar;114(3):404-11 [16507464.001]
  • [Cites] Environ Health Perspect. 2006 Aug;114(8):1193-8 [16882524.001]
  • [Cites] Environ Health Perspect. 2006 Aug;114(8):1293-6 [16882542.001]
  • [Cites] Toxicol Appl Pharmacol. 2006 Sep 15;215(3):295-305 [16712894.001]
  • [Cites] Toxicol Appl Pharmacol. 2006 Nov 1;216(3):407-15 [16876216.001]
  • [Cites] Biochem Biophys Res Commun. 2007 Jan 5;352(1):188-92 [17107663.001]
  • [Cites] Hepatology. 2007 Jan;45(1):205-12 [17187425.001]
  • [Cites] Toxicol Appl Pharmacol. 2007 May 1;220(3):284-91 [17350061.001]
  • [Cites] Toxicology. 2007 Jul 1;236(1-2):7-15 [17451858.001]
  • [Cites] Toxicol Appl Pharmacol. 2007 Jun 15;221(3):295-305 [17481689.001]
  • [Cites] Toxicol Appl Pharmacol. 2007 Aug 1;222(3):271-80 [17306315.001]
  • [Cites] Toxicol Appl Pharmacol. 2007 Aug 1;222(3):365-73 [17397889.001]
  • [Cites] Int Arch Occup Environ Health. 2007 Oct;81(1):9-17 [17387503.001]
  • [Cites] Am J Public Health. 2004 May;94(5):741-4 [15117692.001]
  • [Cites] Indian J Gastroenterol. 1999 Oct-Nov;18(4):152-5 [10531716.001]
  • [Cites] Toxicol Appl Pharmacol. 2000 Jul 1;166(1):24-35 [10873715.001]
  • [Cites] Environ Health Perspect. 2000 Jul;108(7):655-61 [10903620.001]
  • [Cites] J Natl Cancer Inst Monogr. 2000;(27):135-45 [10963625.001]
  • [Cites] Toxicol Sci. 2001 Jan;59(1):185-92 [11134558.001]
  • [Cites] Mol Carcinog. 2001 Feb;30(2):79-87 [11241755.001]
  • [Cites] Toxicol Sci. 2001 Jun;61(2):314-20 [11353140.001]
  • [Cites] Mol Pharmacol. 2001 Aug;60(2):302-9 [11455017.001]
  • [Cites] Toxicol Appl Pharmacol. 2001 Sep 15;175(3):260-8 [11559025.001]
  • [Cites] Carcinogenesis. 2002 Jan;23(1):151-9 [11756236.001]
  • [Cites] Environ Health Perspect. 2002 Feb;110(2):119-22 [11836136.001]
  • [Cites] Carcinogenesis. 2002 May;23(5):777-85 [12016150.001]
  • [Cites] Int J Cancer. 2002 Jul 10;100(2):136-9 [12115560.001]
  • [Cites] Toxicol Sci. 2002 Nov;70(1):13-9 [12388830.001]
  • [Cites] Environ Health Perspect. 2002 Oct;110 Suppl 5:883-6 [12426152.001]
  • [Cites] Toxicol Appl Pharmacol. 2003 Jan 1;186(1):7-17 [12583988.001]
  • [Cites] J Hepatol. 2003 Sep;39(3):383-8 [12927924.001]
  • [Cites] Carcinogenesis. 2003 Nov;24(11):1827-35 [12919961.001]
  • [Cites] Toxicology. 2003 Nov 15;193(1-2):161-9 [14599775.001]
  • [Cites] Mutat Res. 2003 Dec 10;533(1-2):37-65 [14643412.001]
  • (PMID = 18566022.001).
  • [ISSN] 1096-0929
  • [Journal-full-title] Toxicological sciences : an official journal of the Society of Toxicology
  • [ISO-abbreviation] Toxicol. Sci.
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Estrogens; N712M78A8G / Arsenic
  • [Number-of-references] 86
  • [Other-IDs] NLM/ PMC2734307
  •  go-up   go-down


40. Hsu JT, Chen HM, Lin CY, Yeh CN, Hwang TL, Jan YY, Chen MF: Primary angiosarcoma of the spleen. J Surg Oncol; 2005 Dec 15;92(4):312-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the spleen.
  • BACKGROUND AND OBJECTIVES: Primary splenic angiosarcoma is a very rare and aggressive neoplasm with a high metastatic rate and dismal prognosis.
  • METHODS: The records of all cases of primary splenic angiosarcoma treated at Chang Gung Memorial Hospital from April 1991 to July 2004 were retrospectively reviewed.
  • Three patients had distant metastasis to the liver (n = 2), bone (n = 1), bone marrow (n = 1), and small bowel (n = 1) at diagnosis.
  • Liver (n = 3), bone (n = 1), and bone marrow (n = 1) metastases were found in four patients after initial therapy.
  • CONCLUSIONS: The clinical presentations of splenic angiosarcoma were similar to those of previous reports apart from the higher rate of splenomegaly observed in this study.
  • [MeSH-major] Hemangiosarcoma. Splenic Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2005 Wiley-Liss, Inc.
  • (PMID = 16299797.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


41. Puizina-Ivić N, Bezić J, Marasović D, Gotovac V, Carija A, Bozić M: Angiosarcoma arising in sclerodermatous skin. Acta Dermatovenerol Alp Pannonica Adriat; 2005 Mar;14(1):20-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma arising in sclerodermatous skin.
  • We report a case of cutaneous angiosarcoma in a 77-year-old female patient with systemic sclerosis.
  • The pathohistological diagnosis was moderately differentiated angiosarcoma.
  • Despite a notable cutaneous improvement, the control check-up revealed the presence of metastases of the lung and liver.
  • This is the first report of cutaneous angiosarcoma occurring in sclerodermatous skin.
  • [MeSH-major] Facial Neoplasms / etiology. Hemangiosarcoma / etiology. Scleroderma, Systemic / complications. Scleroderma, Systemic / physiopathology. Skin Neoplasms / etiology
  • [MeSH-minor] Aged. Female. Humans. Liver Neoplasms / secondary. Lung Neoplasms / secondary

  • MedlinePlus Health Information. consumer health - Scleroderma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15818442.001).
  • [ISSN] 1318-4458
  • [Journal-full-title] Acta dermatovenerologica Alpina, Pannonica, et Adriatica
  • [ISO-abbreviation] Acta Dermatovenerol Alp Pannonica Adriat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Slovenia
  •  go-up   go-down


42. Gift JS: U.S. EPA's IRIS assessment of 2-butoxyethanol: the relationship of noncancer to cancer effects. Toxicol Lett; 2005 Mar 28;156(1):163-78
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • U.S. EPA's integrated risk information system (IRIS) assessment of 2-butoxyethanol (EGBE) indicates that the human carcinogenic potential of EGBE cannot be determined at this time, but that "suggestive evidence" for cancer exists from laboratory animal studies (hemangiosarcoma of the liver in male mice and forestomach squamous cell papilloma or carcinoma in female mice [National Toxicology Program (NTP), 2000a.

  • Hazardous Substances Data Bank. ETHYLENE GLYCOL MONO-N-BUTYL ETHER .
  • Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15705494.001).
  • [ISSN] 0378-4274
  • [Journal-full-title] Toxicology letters
  • [ISO-abbreviation] Toxicol. Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Carcinogens, Environmental; 0 / Ethers; 0 / Ethylene Glycols; 0 / Solvents; I0P9XEZ9WV / n-butoxyethanol
  • [Number-of-references] 82
  •  go-up   go-down


43. Bolt HM: Vinyl chloride-a classical industrial toxicant of new interest. Crit Rev Toxicol; 2005 Apr-May;35(4):307-23
Hazardous Substances Data Bank. VINYL CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The carcinogenicity of vinyl chloride in humans was recognized in 1974 based on observations of hepatic angiosarcomas in highly exposed workers.
  • The primary target organ, the liver, displays differential susceptibilities of hepatocytes and sinusoidal cells, which are modified by factors of age and dose.
  • Vinyl chloride is a pluripotent carcinogen, predominantly directed toward hepatic endothelial (sinusoidal) cells, and second toward the parenchymal cells of the liver.
  • This is consistent with the plateau of hepatic angiosarcoma incidence in rat bioassays.
  • Published risk estimates based on different sets of data (animal experiments, epidemiological studies) appear basically consistent, and on this basis an angiosarcoma risk of approximately 3 x 10(-4) has been deduced by extrapolation, for exposure to 1 ppm vinyl chloride over an entire human working lifetime.

  • MedlinePlus Health Information. consumer health - Occupational Health.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15989139.001).
  • [ISSN] 1040-8444
  • [Journal-full-title] Critical reviews in toxicology
  • [ISO-abbreviation] Crit. Rev. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens; 0 / Mutagens; 9007-49-2 / DNA; WD06X94M2D / Vinyl Chloride
  • [Number-of-references] 170
  •  go-up   go-down


44. Nakamura M, Tsushima K, Yasuo M, Yamazaki Y, Honda T, Koizumi T, Fujimoto K, Kubo K: Angiosarcoma with sacral origin metastasizing to the lung. Intern Med; 2006;45(15):923-6
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma with sacral origin metastasizing to the lung.
  • Specimens obtained by video-assisted thoracic surgery revealed angiosarcoma, but the primary site of angiosarcoma could not be detected before autopsy.
  • Angiosarcoma is a rare malignant neoplasm with rapid proliferation and they can arise at any region of the body.
  • It can originate in the skin, soft tissue, liver or heart.
  • Their multicentric and local recurrence easily leads us to misdiagnosis, and we have struggled to reach diagnosis and its origin.
  • Angiosarcoma should be included in the different diagnosis of diffuse pulmonary hemorrhage with multiple lung nodules.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Lung Neoplasms / diagnosis. Lung Neoplasms / secondary. Sacrum / pathology. Spinal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16946576.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


45. Odashiro AN, Pereira PR, Odashiro Miiji LN, Nguyen GK: Angiosarcoma of the gallbladder: case report and review of the literature. Can J Gastroenterol; 2005 Apr;19(4):257-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the gallbladder: case report and review of the literature.
  • At autopsy, an angiosarcoma measuring 5 cm in diameter was found in the liver, at the site of the gallbladder fossa.
  • There were multiple hepatic, splenic, ovarian and peritoneal metastases and a massive hemoperitoneum consisting of 8 L of blood and blood clots.
  • Review of the tissue sections from the patient's gallbladder confirmed the presence of an acute hemorrhagic and chronic cholecystitis and also revealed residual foci of an angiosarcoma.
  • A review of eight previously reported cases of gallbladder angiosarcoma is also presented.
  • [MeSH-major] Gallbladder Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Cholecystectomy. Cholecystitis / diagnosis. Cholelithiasis / diagnosis. Fatal Outcome. Female. Hemoperitoneum / etiology. Humans. Middle Aged. Postoperative Complications

  • MedlinePlus Health Information. consumer health - Gallbladder Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15861270.001).
  • [ISSN] 0835-7900
  • [Journal-full-title] Canadian journal of gastroenterology = Journal canadien de gastroenterologie
  • [ISO-abbreviation] Can. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Canada
  • [Number-of-references] 11
  •  go-up   go-down


46. Balamurali G, du Plessis DG, Wengoy M, Bryan N, Herwadkar A, Richardson PL: Thorotrast-induced primary cerebral angiosarcoma: case report. Neurosurgery; 2009 Jul;65(1):E210-1; discussion E211
Hazardous Substances Data Bank. THORIUM DIOXIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thorotrast-induced primary cerebral angiosarcoma: case report.
  • Gliosarcomas, meningiomas, and schwannomas have been reported previously, as has Thorotrast-associated angiosarcoma, typically in the liver.
  • A unique case of a primary intracerebral well-differentiated angiosarcoma in a 68-year-old man with a history of colocalized exposure to Thorotrast is described.
  • This may be the first case of a primary angiosarcoma in the brain.
  • Primary lesions of the central nervous system associated with Thorotrast are very rarely reported, despite its extensive use in cerebral angiography and management of brain abscess between 1930 and 1960.
  • [MeSH-major] Brain Neoplasms / chemically induced. Carcinogens / pharmacology. Hemangiosarcoma / chemically induced. Hemangiosarcoma / diagnosis. Thorium Dioxide / pharmacology

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19574803.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens; 9XA7X17UQC / Thorium Dioxide
  •  go-up   go-down


47. Chen YB, Guo LC, Yang L, Feng W, Zhang XQ, Ling CH, Ji C, Huang JA: Angiosarcoma of the lung: 2 cases report and literature reviewed. Lung Cancer; 2010 Dec;70(3):352-6
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the lung: 2 cases report and literature reviewed.
  • Angiosarcoma is a kind of malignant tumors derived from vascular endothelial cell.
  • Pulmonary angiosarcomas are usually secondary tumors, and primary cases are less than 20 so far.
  • Here we presented two cases of angiosarcoma involved the lung, and we only confirmed case 2 as a primary pulmonary angiosarcoma.
  • The clinical characteristics, diagnosis, treatment options and prognosis of pulmonary angiosarcoma were reviewed in this article too.
  • [MeSH-major] Brain Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Liver Neoplasms / diagnosis. Lung Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20952087.001).
  • [ISSN] 1872-8332
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Antigens, CD34
  •  go-up   go-down


48. Costantini R, Di Bartolomeo N, Francomano F, Angelucci D, Innocenti P: Epithelioid angiosarcoma of the gallbladder: case report. J Gastrointest Surg; 2005 Jul-Aug;9(6):822-5
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid angiosarcoma of the gallbladder: case report.
  • A patient with epithelioid angiosarcoma of the gallbladder is described.
  • Pathophysiological, clinical, and therapeutic aspects are discussed in relation to the available data on angiosarcomas of the gallbladder.
  • [MeSH-major] Cholecystectomy / methods. Gallbladder Neoplasms / pathology. Gallbladder Neoplasms / surgery. Hemangiosarcoma / secondary. Hemangiosarcoma / surgery. Liver Neoplasms / secondary
  • [MeSH-minor] Biopsy, Needle. Follow-Up Studies. Hepatectomy / methods. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Rare Diseases. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Gallbladder Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Surg. 1943 Sep;118(3):445-64 [17858281.001]
  • [Cites] Histopathology. 1994 Mar;24(3):269-71 [7726886.001]
  • [Cites] Surg Gynecol Obstet. 1954 Nov;99(5):529-41 [13205425.001]
  • [Cites] Am Heart J. 1987 May;113(5):1228-30 [3578017.001]
  • [Cites] J Clin Pathol. 1990 Sep;43(9):752-7 [2212067.001]
  • [Cites] Eur J Surg Oncol. 1994 Feb;20(1):63-7 [8131872.001]
  • [Cites] World J Surg. 1982 Jan;6(1):3-9 [7090393.001]
  • [Cites] J Urol. 1987 May;137(5):984-5 [3106655.001]
  • [Cites] Am J Gastroenterol. 1989 Nov;84(11):1431-3 [2816877.001]
  • [Cites] Ann Chir Gynaecol Fenn. 1972;61(3):185-9 [4678469.001]
  • [Cites] Arch Pathol Lab Med. 1983 Jun;107(6):304-7 [6687794.001]
  • (PMID = 15985238.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


49. Lin CF, DeFrias D, Lin X: Epithelioid angiosarcoma: a neoplasm with potential diagnostic challenges. Diagn Cytopathol; 2010 Feb;38(2):154-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid angiosarcoma: a neoplasm with potential diagnostic challenges.
  • Epithelioid angiosarcomas are extremely rare tumors associated with poor prognosis and early metastases.
  • In this report, the patient is a 24-year-old man presenting with testicular pain, a pelvic mass, and innumerable liver nodules.
  • Immediate interpretation of the needle core biopsies of the pelvic mass and liver lesions initially favored a poorly differentiated adenocarcinoma.
  • Further, immunohistochemical evaluation demonstrated positive CD31 and Factor VIII staining and established the final diagnosis of epithelioid angiosarcoma.
  • This case is reported to illustrate the importance of considering the diagnosis of epithelioid angiosarcoma when encountering an "epithelioid" neoplasm particularly with unusual immunoreactivity for CK7 and CD30.
  • [MeSH-minor] Adenocarcinoma / pathology. Diagnosis, Differential. Humans. Immunohistochemistry. Liver Neoplasms / secondary. Male. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19813270.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


50. Thompson WM, Levy AD, Aguilera NS, Gorospe L, Abbott RM: Angiosarcoma of the spleen: imaging characteristics in 12 patients. Radiology; 2005 Apr;235(1):106-15

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the spleen: imaging characteristics in 12 patients.
  • PURPOSE: To retrospectively review clinical, pathologic, and imaging features of angiosarcoma of the spleen in 12 patients.
  • Records of 12 cases of proved angiosarcoma of the spleen were accessed from the files of the Armed Forces Institute of Pathology.
  • Presenting signs and symptoms were recorded, and the pathologist confirmed the diagnosis and determined gross and microscopic morphologic findings in each spleen.
  • Two patients had solitary hypervascular tumors and liver metastases.
  • Angiosarcoma of the spleen could be suggested in the majority of cases (83%) by using the imaging features of splenic mass with evidence of metastatic disease.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Splenic Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) RSNA, 2005
  • (PMID = 15749977.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  •  go-up   go-down


51. Halkes CJ, Dijstelbloem HM, Eelkman Rooda SJ, Kramer MH: Extreme leucocytosis: not always leukaemia. Neth J Med; 2007 Jul-Aug;65(7):248-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This reaction was associated with a hepatic angiosarcoma in the first patient, with a Salmonella infection in the second patient and with a necrotic leg abscess in the third patient.
  • [MeSH-major] Leukemoid Reaction / etiology. Leukocytosis / diagnosis. Leukocytosis / etiology. Paraneoplastic Syndromes
  • [MeSH-minor] Abscess / complications. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Hemangiosarcoma / complications. Humans. Leg / physiopathology. Leukemia. Liver / physiopathology. Male. Salmonella Infections / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17656811.001).
  • [ISSN] 0300-2977
  • [Journal-full-title] The Netherlands journal of medicine
  • [ISO-abbreviation] Neth J Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


52. Yoshida K, Ito F, Nakazawa H, Maeda Y, Tomoe H, Aiba M: A case of primary renal angiosarcoma. Rare Tumors; 2009;1(2):e28

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of primary renal angiosarcoma.
  • Serial CT scans revealed the left kidney mass to be increasing in size and a new lesion in the liver.
  • Renal cell carcinoma with liver metastasis was diagnosed and a radical nephrectomy performed.
  • The initial pathological diagnosis was a benign chronic hematoma.
  • However, the liver mass increased in size and multiplied, while another mass emerged in the twelfth thoracic vertebra with spinal paralysis and was immediately removed.
  • The renal specimen was re-evaluated using whole cross-section analysis and immunohistochemistry, and diagnosed as a primary renal angiosarcoma.
  • Although contrast imaging depicted the primary lesion as a non-specific hematoma with little focal pooling, and low-grade cytological atypia was shown pathologically, the angiosarcoma was extremely aggressive.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21139907.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994470
  •  go-up   go-down


53. Ricchetti T, Paci M, Cavazza A, Ferrari G, Annessi V, De Franco S, Sgarbi G: A case of metastatic epithelioid angiosarcoma in the lamina propria of a sigmoid tubulovillous adenoma. Tumori; 2005 Mar-Apr;91(2):210-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of metastatic epithelioid angiosarcoma in the lamina propria of a sigmoid tubulovillous adenoma.
  • Epithelioid angiosarcoma is an extremely rare tumor.
  • It is generally a secondary tumor and the preferred sites of such metastases are the heart, pericardium, lung, breast, liver, spleen, bone, and brain.
  • In rare cases the lung has been described as the primary site.
  • The prognosis of this neoplasm is extremely poor.
  • We report a case of epithelioid angiosarcoma with multiple bilateral lung infiltration, bone metastasis, and metastasis of the lamina propria of a tubulovillous adenoma of the colon.
  • [MeSH-major] Adenoma / pathology. Basement Membrane / pathology. Epithelioid Cells / pathology. Hemangiosarcoma / pathology. Hemangiosarcoma / secretion. Sigmoid Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15948556.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antigens, CD31
  •  go-up   go-down


54. Burns CJ, Jammer BL, Bodnar CM: Mortality rates among chemical workers in the Kanawha Valley of West Virginia: 1940-1999. W V Med J; 2006 Jul-Aug;102(4):24-8
Hazardous Substances Data Bank. VINYL CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We observed no new cases of angiosarcoma of the liver, a cause of death previously reported in association with vinyl chloride production at the South Charleston location.
  • [MeSH-minor] Adult. Aged. Carcinogens, Environmental / adverse effects. Cause of Death. Cohort Studies. Employment. Female. Follow-Up Studies. Healthy Worker Effect. Hemangiosarcoma / chemically induced. Hemangiosarcoma / mortality. Humans. Liver Neoplasms / chemically induced. Liver Neoplasms / mortality. Lymphoma, Large B-Cell, Diffuse / chemically induced. Lymphoma, Large B-Cell, Diffuse / mortality. Lymphoma, Non-Hodgkin / chemically induced. Lymphoma, Non-Hodgkin / mortality. Male. Middle Aged. Risk. Risk Factors. Sex Factors. Time Factors. Vinyl Chloride / adverse effects. West Virginia

  • MedlinePlus Health Information. consumer health - Occupational Health.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] W V Med J. 2006 Sep-Oct;102(5):5 [17285946.001]
  • (PMID = 17111678.001).
  • [ISSN] 0043-3284
  • [Journal-full-title] The West Virginia medical journal
  • [ISO-abbreviation] W V Med J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens, Environmental; WD06X94M2D / Vinyl Chloride
  •  go-up   go-down


55. Kamo R, Ishina K, Hirata C, Doi K, Nakanishi T, Harada T, Ishii M: A case of ileoileal intussusception caused by metastatic pedunculated tumor of cutaneous angiosarcoma. J Dermatol; 2005 Aug;32(8):638-40
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of ileoileal intussusception caused by metastatic pedunculated tumor of cutaneous angiosarcoma.
  • Cutaneous angiosarcoma is a rare aggressive vascular tumor that occurs in elderly patients and is usually located on the head and face.
  • Metastases often develop in the cervical lymph nodes, lungs, bone, liver and spleen.
  • There have been no reports of ileoileal intussusception due to metastatic tumor from cutaneous angiosarcoma.
  • We reported a case of cutaneous angiosarcoma in a 67-year-old Japanese male accompanied with ileoileal intussusception due to metastatic angiosarcoma.
  • We assume that the metastatic tumor in the small intestine was metastasized hematogeneously from cutaneous angiosarcoma, resulting in the formation of nodules and the rapid growth of a pedunculated tumor as a forerunner of the ileoileal intessusception.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Ileal Neoplasms / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Ileal Diseases / etiology. Intussusception / etiology. Male. Scalp

  • MedlinePlus Health Information. consumer health - Intestinal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16334863.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


56. Park JW, Serafica-Karen C, Das K: Fine-needle aspiration of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver: A diagnostic dilemma. Diagn Cytopathol; 2010 Oct;38(10):768-71
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver: A diagnostic dilemma.
  • Radiation therapy is a significant risk factor for the development of angiosarcoma.
  • With the increase in breast conservation treatment, the incidence of cutaneous radiation-induced angiosarcoma of the breast is rising.
  • If the angiosarcoma demonstrates epithelioid features, the tumor cells may present a diagnostic dilemma on fine-needle aspiration cytology.
  • We present a case of metastatic radiation-induced cutaneous epithelioid angiosarcoma of the breast to the liver and a review of the literature.
  • [MeSH-major] Biopsy, Fine-Needle. Liver Neoplasms / secondary. Neoplasms, Radiation-Induced / pathology
  • [MeSH-minor] Breast Neoplasms / metabolism. Breast Neoplasms / secondary. Carcinoma in Situ / radiotherapy. Carcinoma in Situ / surgery. Carcinoma, Ductal, Breast / radiotherapy. Carcinoma, Ductal, Breast / surgery. Cytodiagnosis. Diagnosis, Differential. Female. Hemangiosarcoma / metabolism. Hemangiosarcoma / secondary. Humans. Immunohistochemistry. Mastectomy, Segmental. Middle Aged. Radiotherapy, Adjuvant / adverse effects. Skin Neoplasms / metabolism. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2010 Wiley-Liss, Inc.
  • (PMID = 20187111.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Angiosarcoma of the breast
  •  go-up   go-down


57. Vasanawala MS, Wang Y, Quon A, Gambhir SS: F-18 fluorodeoxyglucose PET/CT as an imaging tool for staging and restaging cutaneous angiosarcoma of the scalp. Clin Nucl Med; 2006 Sep;31(9):534-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] F-18 fluorodeoxyglucose PET/CT as an imaging tool for staging and restaging cutaneous angiosarcoma of the scalp.
  • Cutaneous angiosarcoma of the scalp is a rare highly aggressive malignant tumor that typically afflicts elderly patients and commonly presents with extensive local spread and distant metastasis.
  • Distant metastases favor lung, liver, lymph nodes, and skin.
  • We report the case of a 70-year-old man diagnosed with multifocal angiosarcoma of the scalp.
  • PET/CT imaging with F-18 2-fluoro-2-deoxyglucose (F-18 FDG) not only showed avid FDG uptake by an angiosarcoma (SUVmax = 10.7), but also simultaneously showed local extension of multifocal lesions with periosteal involvement and excluded metastatic abdominal nodal disease.
  • Evaluation of more cases of this subset of soft tissue sarcoma with FDG PET/CT may suggest a possible role in not only staging angiosarcomas to determine the extent of local as well as distant disease, but also to potentially help determine response to therapy and early recognition of local or distant recurrence.
  • [MeSH-major] Fluorodeoxyglucose F18. Hemangiosarcoma / diagnosis. Hemangiosarcoma / radionuclide imaging. Neoplasm Staging / methods. Positron-Emission Tomography / methods. Radiopharmaceuticals. Scalp / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / radionuclide imaging. Tomography, X-Ray Computed / methods

  • MedlinePlus Health Information. consumer health - CT Scans.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16921276.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  •  go-up   go-down


58. Mignogna C, Simonetti S, Galloro G, Magno L, De Cecio R, Insabato L: Duodenal epithelioid angiosarcoma: immunohistochemical and clinical findings. A case report. Tumori; 2007 Nov-Dec;93(6):619-21
MedlinePlus Health Information. consumer health - Intestinal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Duodenal epithelioid angiosarcoma: immunohistochemical and clinical findings. A case report.
  • Angiosarcomas are uncommon malignant tumors of vascular endothelium that represent less than 1% of all sarcomas.
  • The epithelioid variant of angiosarcomas is exceptionally rare, and the gastrointestinal tract is rarely involved.
  • Angiosarcomas mainly involve skin and soft tissue and rarely occur in breast, liver, bone, and spleen.
  • A duodenal reddish polypoid lesion was found, which on microscopic examination turned out to be an epithelioid angiosarcoma.
  • The immunohistochemical features of the lesion supported this diagnosis.
  • The patient died eight months after the diagnosis.
  • Epithelioid angiosarcoma is an aggressive variant of angiosarcoma and must be considered in the differential diagnosis of gastrointestinal tumors.
  • [MeSH-major] Duodenal Neoplasms / pathology. Hemangioendothelioma, Epithelioid / pathology. Hemangiosarcoma / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18338501.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


59. Ishibashi N, Mitachi Y, Sugawara S, Shinozaki S, Miura M, Fukuju T, Katahira Y, Koyama K, Fujikawa N, Kato T, Murakami K: [A case of cardiac angiosarcoma successfully treated with docetaxel]. Gan To Kagaku Ryoho; 2007 Nov;34(11):1849-52
Hazardous Substances Data Bank. DOCETAXEL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of cardiac angiosarcoma successfully treated with docetaxel].
  • We report a case of angiosarcoma of the right atrium presenting superior vena cava syndrome.
  • The pathological diagnosis was angiosarcoma.
  • The patient agreed to chemotherapy with docetaxel, which is known to be often effective against angiosarcoma of the scalp or face.
  • The tumor, however, became resistant to docetaxel and formed metastatic involvements in the liver.
  • Following treatments with paclitaxel, IL-2 and CPT-11 were ineffective for the primary tumor and liver metastases.
  • He had long-term survival 31 months after the diagnosis.
  • An effective treatment for cardiac angiosarcoma has not yet been established.
  • Chemotherapy with docetaxel should be considered in the treatment of patients with cardiac angiosarcoma.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Heart Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Taxoids / therapeutic use
  • [MeSH-minor] Drug Administration Routes. Drug Resistance, Neoplasm. Heart Atria. Humans. Liver Neoplasms / secondary. Male. Middle Aged

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18030022.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Taxoids; 15H5577CQD / docetaxel
  •  go-up   go-down


60. Kopp HG, Kanz L, Hartmann JT: Complete remission of relapsing high-grade angiosarcoma with single-agent metronomic trofosfamide. Anticancer Drugs; 2006 Sep;17(8):997-8
Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Complete remission of relapsing high-grade angiosarcoma with single-agent metronomic trofosfamide.
  • A limited repertoire of chemotherapeutics is available for the therapy of metastasizing angiosarcoma.
  • We report on a case from our clinic, in which a complete response with oral trofosfamide was achieved in a patient suffering from relapsed high-grade angiosarcoma metastasizing to the liver and lung.
  • [MeSH-major] Antineoplastic Agents, Alkylating / therapeutic use. Cyclophosphamide / analogs & derivatives. Hemangiosarcoma / drug therapy. Neoplasm Recurrence, Local / drug therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16940811.001).
  • [ISSN] 0959-4973
  • [Journal-full-title] Anti-cancer drugs
  • [ISO-abbreviation] Anticancer Drugs
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 8N3DW7272P / Cyclophosphamide; H64JRU6GJ0 / trofosfamide
  •  go-up   go-down


61. Glickstein J, Sebelik ME, Lu Q: Cutaneous angiosarcoma of the head and neck: a case presentation and review of the literature. Ear Nose Throat J; 2006 Oct;85(10):672-4
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous angiosarcoma of the head and neck: a case presentation and review of the literature.
  • Cutaneous angiosarcoma of the head and neck is a rare vascular neoplasm.
  • Early diagnosis and treatment are essential for local control of this aggressive tumor but recognition can be delayed because of its rarity or because of difficulty in making a pathologic diagnosis.
  • After a diagnosis of low-grade angiosarcoma was definitively established, the lesions were locally excised with good cosmetic and functional results.
  • We review the literature on cutaneous angiosarcoma, and we discuss its epidemiology, presentation, tissue diagnosis, treatment, and prognosis in an effort to increase awareness of this rare malignancy.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Humans. Liver Neoplasms / secondary. Male. Prognosis. Retroperitoneal Neoplasms / secondary. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Head and Neck Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17124942.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
  •  go-up   go-down


62. Luk A, Nwachukwu H, Lim KD, Cusimano RJ, Butany J: Cardiac angiosarcoma: a case report and review of the literature. Cardiovasc Pathol; 2010 May-Jun;19(3):e69-74

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac angiosarcoma: a case report and review of the literature.
  • We present the case of a 36-year-old woman with widespread metastatic cardiac angiosarcoma to the lungs and the liver.
  • [MeSH-major] Heart Neoplasms / pathology. Hemangiosarcoma / secondary
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Cardiovascular Surgical Procedures. Combined Modality Therapy. Female. Humans. Liver Neoplasms / secondary. Liver Neoplasms / therapy. Lung Neoplasms / secondary. Lung Neoplasms / therapy. Neoadjuvant Therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19150248.001).
  • [ISSN] 1879-1336
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 34
  •  go-up   go-down


63. Bien E, Stachowicz-Stencel T, Balcerska A, Godzinski J, Kazanowska B, Perek-Polnik M, Madziara W, Rybczynska A, Kurylak A, Zalewska-Szewczyk B, Peregud-Pogorzelski J: Angiosarcoma in children - still uncontrollable oncological problem. The report of the Polish Paediatric Rare Tumours Study. Eur J Cancer Care (Engl); 2009 Jul;18(4):411-20
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma in children - still uncontrollable oncological problem. The report of the Polish Paediatric Rare Tumours Study.
  • Angiosarcoma in children - still uncontrollable oncological problem.
  • The report of the Polish Paediatric Rare Tumours StudyAngiosarcoma is a rare, highly malignant vascular neoplasm with little data available on its clinical course and management in children.
  • Ten children with angiosarcoma (M/F: 6/4; aged 2, 3-16 years) registered in Polish Paediatric Rare Tumours and Soft Tissue Sarcomas Studies between 1992 and 2006.
  • Primary tumour exceeded 5 cm in seven patients and affected mainly deep tissues (heart-2, head/neck, bladder, brain, liver and upper limb - one patient each).
  • Complete primary excision was unfeasible even in local stages.
  • Angiosarcoma in children is highly aggressive with an extremely poor prognosis.
  • Complete primary excision is unfeasible, even in seemingly local stages.
  • [MeSH-major] Hemangiosarcoma / pathology. Hemangiosarcoma / therapy. Sarcoma / pathology. Sarcoma / therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19490008.001).
  • [ISSN] 1365-2354
  • [Journal-full-title] European journal of cancer care
  • [ISO-abbreviation] Eur J Cancer Care (Engl)
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


64. Hosokawa Y, Kodani E, Kusama Y, Kamiya M, Yoshikawa M, Hirasawa Y, Nakagomi A, Atarashi H, Maeda S, Mizuno K: Cardiac angiosarcoma diagnosed by transvenous endomyocardial biopsy with the aid of transesophageal echocardiography and intra-procedural consultation. Int Heart J; 2010;51(5):367-9
MedlinePlus Health Information. consumer health - Biopsy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac angiosarcoma diagnosed by transvenous endomyocardial biopsy with the aid of transesophageal echocardiography and intra-procedural consultation.
  • Transthoracic echocardiography (TTE) and contrast-enhanced computed tomography (CT) scans demonstrated a large mass in the right atrium and multiple liver tumors thought to be due to spread of the disease.
  • In order to confirm the histological diagnosis, we attempted transvenous endomyocardial tumor biopsy under fluoroscopic guidance.
  • These findings indicated a definite diagnosis of angiosarcoma.
  • [MeSH-major] Biopsy / methods. Heart Neoplasms / diagnosis. Heart Neoplasms / pathology. Hemangiosarcoma / pathology. Ultrasonography, Interventional / methods
  • [MeSH-minor] Coronary Angiography. Dose Fractionation. Echocardiography, Transesophageal. Female. Humans. Immunohistochemistry. Liver Neoplasms / radiography. Liver Neoplasms / secondary. Middle Aged. Referral and Consultation. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20966612.001).
  • [ISSN] 1349-3299
  • [Journal-full-title] International heart journal
  • [ISO-abbreviation] Int Heart J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


65. Beland FA, Benson RW, Mellick PW, Kovatch RM, Roberts DW, Fang JL, Doerge DR: Effect of ethanol on the tumorigenicity of urethane (ethyl carbamate) in B6C3F1 mice. Food Chem Toxicol; 2005 Jan;43(1):1-19
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hepatic levels of the DNA adduct 1,N(6)-ethenodeoxyadenosine were increased by exposure to urethane and decreased by treatment with ethanol.
  • Urethane caused dose-dependent increases in liver, lung, and harderian gland adenoma or carcinoma and hemangiosarcoma of the liver and heart in both sexes, mammary gland and ovarian tumors in females, and squamous cell papilloma or carcinoma of the skin and forestomach in males.
  • The increase in hepatocellular tumors occurred in a relatively linear manner and was attributed to the formation of 1,N(6)-ethenodeoxyadenosine in hepatic DNA coupled with an increase in cell replication.
  • In female mice administered 10 ppm and 90 ppm urethane, ethanol caused dose-related increases in alveolar/bronchiolar adenoma or carcinoma and hemangiosarcoma of the heart, respectively.
  • [MeSH-minor] Animals. Apoptosis / drug effects. Body Weight / drug effects. Carcinogenicity Tests. Cell Division / drug effects. Cytochrome P-450 Enzyme System / metabolism. DNA Adducts. Dose-Response Relationship, Drug. Female. Liver / drug effects. Liver / enzymology. Liver / pathology. Lung / drug effects. Lung / pathology. Male. Mice. Mice, Inbred Strains. Random Allocation. Sex Factors. Survival Analysis

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. ETHYL CARBAMATE .
  • Hazardous Substances Data Bank. ETHANOL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15582191.001).
  • [ISSN] 0278-6915
  • [Journal-full-title] Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • [ISO-abbreviation] Food Chem. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Carcinogens; 0 / DNA Adducts; 3IN71E75Z5 / Urethane; 3K9958V90M / Ethanol; 9035-51-2 / Cytochrome P-450 Enzyme System
  •  go-up   go-down


66. Gambino G, Mannone T, Rizzo A, Scio A, Branca M, Airò Farulla M, Guccione M, Spallitta IS, Nicoli N: Adrenal epithelioid angiosarcoma: a case report. Chir Ital; 2008 May-Jun;60(3):463-7
MedlinePlus Health Information. consumer health - Adrenal Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adrenal epithelioid angiosarcoma: a case report.
  • We report what to the best of our knowledge is the first case of primary angiosarcoma of the adrenal gland.
  • Computed tomography revealed a suspected rupture of a liver neoplasm and surgical treatment was performed.
  • At laparotomy there was no evidence of liver tumour but a large mass was found in the right adrenal gland.
  • [MeSH-major] Adrenal Gland Neoplasms. Hemangiosarcoma

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18709789.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


67. den Hoed ID, Granzen B, Granzen B, Aronson DC, Pauwels P, de Kraker J, van Heurn LW: Metastasized angiosarcoma of the spleen in a 2-year-old girl. Pediatr Hematol Oncol; 2005 Jul-Aug;22(5):387-90
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasized angiosarcoma of the spleen in a 2-year-old girl.
  • Primary angiosarcoma of the spleen is rare and the prognosis is very poor.
  • The authors present a 2-year-old girl with spontaneous rupture of splenic angiosarcoma.
  • At diagnosis there were liver metastases.
  • After splenectomy she received chemotherapy with ifosfamide, vincristine, and actinomycine D combined with a partial liver resection.
  • She remained in complete remission over 2 years from diagnosis.
  • [MeSH-major] Hemangiosarcoma / secondary. Liver Neoplasms / secondary. Splenic Neoplasms / pathology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child, Preschool. Female. Hepatectomy. Humans. Neoplasm Metastasis. Prognosis. Remission Induction

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16020128.001).
  • [ISSN] 0888-0018
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


68. Nascimento AF, Raut CP, Fletcher CD: Primary angiosarcoma of the breast: clinicopathologic analysis of 49 cases, suggesting that grade is not prognostic. Am J Surg Pathol; 2008 Dec;32(12):1896-904
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the breast: clinicopathologic analysis of 49 cases, suggesting that grade is not prognostic.
  • Mammary angiosarcoma is a rare neoplasm, accounting for about 0.05% of all primary malignancies of the breast.
  • It is currently believed that histologic grading of mammary angiosarcomas plays an important role in prognostication.
  • Forty-nine cases of primary angiosarcoma of the breast were retrieved from our files.
  • Histologically, primary tumors were graded using Rosen's 3-tier system: 17 tumors (35.4%) as low grade, 17 (35.4%) as intermediate grade, and 14 (29.2%) as high grade.
  • Ten patients (24.4%) showed evidence of local recurrence within 11 to 60 months (median 36) after diagnosis.
  • Twenty-four patients (58.5%) thus far have developed metastases, which were most commonly to lung, liver, skin, and bone.
  • Time interval between diagnosis and metastasis ranged from 2 to 144 months (median 34).
  • In conclusion, mammary angiosarcoma is a rare disease that affects relatively younger patients.
  • This tumor seems to have an overall similar clinical course as other types of angiosarcoma arising in skin or soft tissue; it carries a moderate risk of local recurrence, and a high risk of metastasis and death.
  • In this large series, there is no correlation between histologic grade and patient outcome, more in line with angiosarcomas at other sites.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology

  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18813119.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


69. Ikeya E, Taguchi J, Yamaguchi M, Shibuya M, Kanabuchi K: Primary cardiac angiosarcoma: presenting with cardiac tamponade followed by cerebral hemorrhage with brain metastases. Jpn J Thorac Cardiovasc Surg; 2006 Dec;54(12):528-31
MedlinePlus Health Information. consumer health - Pericardial Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac angiosarcoma: presenting with cardiac tamponade followed by cerebral hemorrhage with brain metastases.
  • Pathology examination of samples at pericardiotomy revealed them to be angiosarcoma.
  • Primary cardiac angiosarcoma is rare, and mostly arises from the right side of the heart.
  • Common metastatic sites are the lungs and liver.
  • In conclusion, this is a rare report of cardiac angiosarcoma presenting with pericardial tamponade.
  • [MeSH-major] Brain Neoplasms / complications. Brain Neoplasms / secondary. Cardiac Tamponade / etiology. Cerebral Hemorrhage / etiology. Heart Neoplasms / pathology. Hemangiosarcoma / pathology

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Pathol Lab Med. 1998 Mar;122(3):273-6 [9823868.001]
  • [Cites] Heart. 1999 May;81(5):556-8 [10212178.001]
  • [Cites] AJNR Am J Neuroradiol. 1995 Sep;16(8):1739-41 [7502986.001]
  • [Cites] Cancer. 1992 Jan 15;69(2):387-95 [1728367.001]
  • [Cites] No Shinkei Geka. 1988;16(5 Suppl):579-84 [2840591.001]
  • [Cites] Cancer. 1996 Jun 1;77(11):2400-6 [8635113.001]
  • [Cites] Heart. 2001 Dec;86(6):665 [11711463.001]
  • [Cites] Cancer. 1986 Feb 15;57(4):852-9 [3510706.001]
  • [Cites] Cancer. 1995 Feb 15;75(4):989-96 [7842420.001]
  • [Cites] J Thorac Cardiovasc Surg. 1992 Apr;103(4):655-64 [1548908.001]
  • (PMID = 17236655.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


70. Sakurai H, Hada M, Miyashita Y, Tsukamoto K, Oyama T, Ashizawa I: Simultaneous bilateral spontaneous pneumothorax secondary to metastatic angiosarcoma of the scalp: report of a case. Surg Today; 2006;36(10):919-22
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Simultaneous bilateral spontaneous pneumothorax secondary to metastatic angiosarcoma of the scalp: report of a case.
  • Angiosarcoma is a highly malignant neoplasm, which most often develops on the scalp or face of elderly people.
  • Common distant metastatic sites include the lung, liver, lymph nodes, and skin.
  • We report a case of angiosarcoma manifesting as simultaneous bilateral spontaneous pneumothorax secondary to pulmonary metastases in an 86-year-old man.
  • The pneumothorax preceded the diagnosis of angiosarcoma.
  • This case suggests that a finding of simultaneous bilateral spontaneous pneumothorax may indicate a serious parenchymal lung disorder.
  • [MeSH-major] Head and Neck Neoplasms / complications. Hemangiosarcoma / complications. Lung Neoplasms / complications. Pneumothorax / etiology. Scalp. Skin Neoplasms / complications

  • MedlinePlus Health Information. consumer health - Collapsed Lung.
  • MedlinePlus Health Information. consumer health - Head and Neck Cancer.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Comput Radiol. 1985 Mar-Apr;9(2):115-20 [3858045.001]
  • [Cites] Chest. 1994 Jul;106(1):4-5 [8020318.001]
  • [Cites] Am Rev Respir Dis. 1989 Jan;139(1):252-3 [2912348.001]
  • [Cites] Br J Radiol. 1990 Feb;63(746):132-4 [2095744.001]
  • [Cites] Chest. 1994 Apr;105(4):1142-6 [8162740.001]
  • [Cites] Surg Today. 2004;34(10):817-21 [15449149.001]
  • [Cites] Cancer. 1995 Feb 15;75(4):989-96 [7842420.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1987;412(1):83-7 [3120405.001]
  • [Cites] Mayo Clin Proc. 1973 Aug;48(8):541-4 [4352472.001]
  • [Cites] Acta Chir Belg. 2004 Oct;104(5):572-6 [15571026.001]
  • [Cites] AJR Am J Roentgenol. 1983 Mar;140(3):473-4 [6600536.001]
  • [Cites] J Korean Med Sci. 2003 Apr;18(2):277-80 [12692429.001]
  • (PMID = 16998687.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


71. Asmane I, Litique V, Heymann S, Marcellin L, Métivier AC, Duclos B, Bergerat JP, Kurtz JE: Adriamycin, cisplatin, ifosfamide and paclitaxel combination as front-line chemotherapy for locally advanced and metastatic angiosarcoma. Analysis of three case reports and review of the literature. Anticancer Res; 2008 Sep-Oct;28(5B):3041-5
SciCrunch. KEGG: Data: Disease Annotation .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adriamycin, cisplatin, ifosfamide and paclitaxel combination as front-line chemotherapy for locally advanced and metastatic angiosarcoma. Analysis of three case reports and review of the literature.
  • Angiosarcoma represents 1 to 2% of soft tissue tumors.
  • It originates from endothelial cells of small blood vessels and may affect a variety of organs, including the retroperitoneum, skeletal muscle, subcutis, liver, heart and breast.
  • The outcome of angiosarcoma is poor for those patients in whom aggressive surgery cannot be considered.
  • We report three cases of angiosarcoma in which first-line chemotherapy with adriamycin 40 mg/m2 day 1, ifosfamide 3 g/m2 day 1-2, cisplatin 35 mg/m2 day 1-2 and paclitaxel 175 mg/m2 day 3 led to clinically meaningful responses.
  • We emphasize the need for designing trials specifically dedicated to angiosarcomas, as this rare and severe condition may be a target for new antiangiogenic drugs.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / drug therapy. Breast Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Soft Tissue Neoplasms / drug therapy

  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. TAXOL .
  • Hazardous Substances Data Bank. IFOSFAMIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19031953.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 80168379AG / Doxorubicin; P88XT4IS4D / Paclitaxel; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide
  •  go-up   go-down


72. Castro EC, Galambos C, Shaw PH, Ranganathan S: Primary mesenteric angiosarcoma in a child with associated lymphangiectasia: a case report. Pediatr Dev Pathol; 2008 Nov-Dec;11(6):482-6
Genetic Alliance. consumer health - Lymphangiectasis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mesenteric angiosarcoma in a child with associated lymphangiectasia: a case report.
  • Angiosarcomas are rare tumors in children, usually occurring in soft tissue and liver.
  • By contrast, angiosarcoma in adults usually occurs in the extremities in conjunction with lymphedema.
  • Mesenteric angiosarcoma has only rarely been reported.
  • When angiosarcomas arise in this location, they usually represent a 2nd malignancy following Hodgkin's lymphoma.
  • We report a child who presented to the emergency room with an acute abdomen and underwent emergency surgery for a mesenteric angiosarcoma with associated lymphangiectasia of the bowel and mesentery.
  • [MeSH-major] Hemangiosarcoma / secondary. Lymphangiectasis, Intestinal / pathology. Peritoneal Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19143455.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


73. Wang XY, Jakowski J, Tawfik OW, Thomas PA, Fan F: Angiosarcoma of the breast: a clinicopathologic analysis of cases from the last 10 years. Ann Diagn Pathol; 2009 Jun;13(3):147-50
MedlinePlus Health Information. consumer health - Breast Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the breast: a clinicopathologic analysis of cases from the last 10 years.
  • Breast angiosarcoma may occur de novo, or as a complication of radiation therapy, or chronic lymphedema secondary to axillary lymph node dissection for mammary carcinoma.
  • In our effort to characterize the clinicopathologic features of breast angiosarcoma, we reviewed all breast angiosarcoma cases in the University of Kansas Medical Center and Ohio State University Medical Center archives from 1997 to 2007.
  • Only 11 angiosarcomas were identified among more than 5000 malignant breast neoplasms (0.1%-0.2% incidence) for the last 10 years.
  • Eight cases (6 high grade, 1 intermediate grade, 1 low grade) were identified as postradiation angiosarcoma (postradiation time interval, 4-12 years), and 3 cases were identified as primary angiosarcomas (1 high grade, 2 low grade).
  • Follow-up (median, 36 months) revealed that 3 cases of postradiation angiosarcoma recurred as skin and/or chest wall lesions and 1 case of primary angiosarcoma developed liver metastases (all high-grade).
  • In conclusion, breast angiosarcoma remains a rare disease.
  • Rosen's method for grading breast angiosarcoma is easy to implement and correlates well with clinical outcome.
  • There are no distinct clinical or histologic differences between primary and postradiation breast angiosarcomas.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Combined Modality Therapy. Female. Humans. Mastectomy. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Neoplasms, Radiation-Induced / pathology. Neoplasms, Radiation-Induced / therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19433291.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
  •  go-up   go-down


74. Valbuena JR, Levenback C, Mansfield P, Liu J: Angiosarcoma of the spleen clinically presenting as metastatic ovarian cancer. A case report and review of the literature. Ann Diagn Pathol; 2005 Oct;9(5):289-92
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the spleen clinically presenting as metastatic ovarian cancer. A case report and review of the literature.
  • Primary angiosarcomas of the spleen are rare and almost always fatal.
  • Grossly, this neoplasm appears as hemorrhagic and/or cystic nodules, with a low-density signal seen on computed tomographic scans.
  • The differential diagnosis includes a variety of benign and malignant vascular proliferations (littoral cell angioma and Kaposi's sarcoma) as well as metastatic tumors.
  • The liver is the most common site.
  • However, histopathologic examination of the specimen showed the tumor to be of a primary angiosarcoma.
  • We believe that the lengthy exposure to radiation may have played a role in the histopathogenesis of this neoplasm in this patient.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Second Primary / pathology. Ovarian Neoplasms / pathology. Splenic Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans


75. Berretta M, Rupolo M, Buonadonna A, Canzonieri V, Brollo A, Morra A, Berretta S, Bearz A, Tirelli U, Frustaci S: Metastatic angiosarcoma of the kidney: a case report with treatment approach and review of the literature. J Chemother; 2006 Apr;18(2):221-4
Hazardous Substances Data Bank. IFOSFAMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic angiosarcoma of the kidney: a case report with treatment approach and review of the literature.
  • Angiosarcomas are rare soft tissue malignancies.
  • We report the case of a 67-year-old man affected by a large angiosarcoma of the kidney.
  • [MeSH-major] Hemangiosarcoma / drug therapy. Hemangiosarcoma / surgery. Kidney Neoplasms / drug therapy. Kidney Neoplasms / surgery
  • [MeSH-minor] Aged. Anthracyclines / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Fatal Outcome. Humans. Ifosfamide / administration & dosage. Liver Neoplasms / secondary. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Male. Nephrectomy. Palliative Care. Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / secondary. Splenic Neoplasms / drug therapy. Splenic Neoplasms / secondary. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Kidney Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16736893.001).
  • [ISSN] 1120-009X
  • [Journal-full-title] Journal of chemotherapy (Florence, Italy)
  • [ISO-abbreviation] J Chemother
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Anthracyclines; UM20QQM95Y / Ifosfamide
  •  go-up   go-down


76. Sahmel J, Unice K, Scott P, Cowan D, Paustenbach D: The use of multizone models to estimate an airborne chemical contaminant generation and decay profile: occupational exposures of hairdressers to vinyl chloride in hairspray during the 1960s and 1970s. Risk Anal; 2009 Dec;29(12):1699-725
Hazardous Substances Data Bank. VINYL CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The question has arisen whether occupational exposures of hairdressers to VC-containing hairsprays in hair salons were sufficient to increase the risk for developing hepatic angiosarcoma (HAS).
  • [MeSH-minor] Beauty Culture. Female. Hemangiosarcoma / epidemiology. Hemangiosarcoma / etiology. Hemangiosarcoma / history. History, 20th Century. Humans. Liver Neoplasms / epidemiology. Liver Neoplasms / etiology. Liver Neoplasms / history. Models, Theoretical. Occupational Diseases / epidemiology. Occupational Diseases / etiology. Occupational Diseases / history. Risk Assessment. United States / epidemiology. United States Occupational Safety and Health Administration

  • MedlinePlus Health Information. consumer health - Occupational Health.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19948002.001).
  • [ISSN] 1539-6924
  • [Journal-full-title] Risk analysis : an official publication of the Society for Risk Analysis
  • [ISO-abbreviation] Risk Anal.
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Air Pollutants, Occupational; 0 / Hair Preparations; WD06X94M2D / Vinyl Chloride
  •  go-up   go-down


77. Dragani TA, Zocchetti C: Occupational exposure to vinyl chloride and risk of hepatocellular carcinoma. Cancer Causes Control; 2008 Dec;19(10):1193-200
Hazardous Substances Data Bank. VINYL CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Liver angiosarcoma is a rare cancer that develops from endothelial cells and whose most relevant known risk factor is occupational exposure to vinyl chloride (VC).
  • Carcinogenesis bioassays of VC inhalation in rodents indicate that angiosarcomas account for nearly all liver tumors induced.
  • [MeSH-major] Carcinogens / toxicity. Carcinoma, Hepatocellular / chemically induced. Liver Neoplasms / chemically induced. Occupational Exposure. Vinyl Chloride / toxicity

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • MedlinePlus Health Information. consumer health - Occupational Health.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Cancer Causes Control. 2009 May;20(4):505-6; author reply 507-8 [19039674.001]
  • (PMID = 18560983.001).
  • [ISSN] 1573-7225
  • [Journal-full-title] Cancer causes & control : CCC
  • [ISO-abbreviation] Cancer Causes Control
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Carcinogens; WD06X94M2D / Vinyl Chloride
  •  go-up   go-down


78. Hara T, Tsurumi H, Kasahara S, Ogawa K, Takada J, Imai K, Takai K, Kitagawa J, Kiyama S, Imai N, Oyama M, Takami T, Moriwaki H: Long-term survival of a patient with splenic angiosarcoma after resection, high-dose chemotherapy, and autologous peripheral blood stem cell transplantation. Intern Med; 2010;49(20):2253-7
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term survival of a patient with splenic angiosarcoma after resection, high-dose chemotherapy, and autologous peripheral blood stem cell transplantation.
  • Histological examination was typical for angiosarcoma.
  • CT scan showed a hepatic tumor.
  • A fine-needle biopsy of the liver revealed the first relapse.
  • Despite hepatic lobectomy, radiofrequency ablations and administration of recombinant interleukin-2, she died from respiratory failure in 2009.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Hemangiosarcoma / therapy. Peripheral Blood Stem Cell Transplantation. Splenectomy. Splenic Neoplasms / therapy

  • Genetic Alliance. consumer health - Transplantation.
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • Hazardous Substances Data Bank. PREDNISONE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20962445.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Interleukin-3; 0 / Recombinant Proteins; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
  •  go-up   go-down


79. Kostov D, Kobakov G, Dragnev N: [Operative-technical special features of the left lobectomy in colorectal cancer liver metastases]. Khirurgiia (Sofiia); 2006;(6):8-11
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Operative-technical special features of the left lobectomy in colorectal cancer liver metastases].
  • The indications of the liver resection are the primary and secondary malignant neoplasms of the liver, the benign liver tumors and some inflammatory diseases.
  • Approximately 10-30% of the patients with colorectal cancer liver metastases are suitable to a curative liver resection.
  • The aim of the study is to presenti of the operative-technical special features of the anatomical left lobectomy of patients with colorectal cancer liver metastases.
  • In the course of 24 months we carried out 9 anatomical left liver resections.
  • The indications of the operation of eight of them were solitary metastases, which had appeared after an operation on colorectal cancer and at one of them the resection was performed due to an angiosarcoma of the liver.
  • The liver resection highly improves the prognosis on the following conditions: a radical treatment of the primary tumor, an absence of local recurrence, an absence of an extrahepatic incidence of the primary tumor and a preservation of a sufficient capacity of the liver.
  • [MeSH-major] Adenocarcinoma / surgery. Colorectal Neoplasms / pathology. Hepatectomy / methods. Liver Neoplasms / surgery


80. Arbiser JL, Bonner MY, Berrios RL: Hemangiomas, angiosarcomas, and vascular malformations represent the signaling abnormalities of pathogenic angiogenesis. Curr Mol Med; 2009 Nov;9(8):929-34
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemangiomas, angiosarcomas, and vascular malformations represent the signaling abnormalities of pathogenic angiogenesis.
  • Angiogenesis is a major factor in the development of benign, inflammatory, and malignant processes of the skin.
  • Furthermore, we have studied malignant vascular tumors, including hemangioendothelioma and angiosarcoma and have shown distinct signaling abnormalities in these tumors.
  • The incidence of these tumors is expected to rise due to environmental insults, such as radiation and lumpectomy for breast cancer, dietary and industrial carcinogens (hepatic angiosarcoma), and chronic ultraviolet exposure and potential Agent Orange exposure.
  • I hypothesize that hemangiomas, angiosarcomas, and vascular malformations represent the extremes of signaling abnormalities seen in pathogenic angiogenesis.
  • [MeSH-major] Hemangioma / blood supply. Hemangiosarcoma / blood supply. Neovascularization, Pathologic / pathology. Signal Transduction. Vascular Malformations / physiopathology

  • Genetic Alliance. consumer health - Vascular Malformations.
  • MedlinePlus Health Information. consumer health - Birthmarks.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19925405.001).
  • [ISSN] 1875-5666
  • [Journal-full-title] Current molecular medicine
  • [ISO-abbreviation] Curr. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 81
  •  go-up   go-down


81. Mutlu E, Collins LB, Stout MD, Upton PB, Daye LR, Winsett D, Hatch G, Evansky P, Swenberg JA: Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N(2),3-ethenoguanine in tissues of adult and weanling rats following exposure to [(13)C(2)]-VC. Chem Res Toxicol; 2010 Sep 20;23(9):1485-91
Hazardous Substances Data Bank. VINYL CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the 1970s, exposure to vinyl chloride (VC) was shown to cause liver angiosarcoma in VC workers.
  • The number of endogenous and exogenous εG adducts in DNA from tissues of adult rats exposed to [(13)C(2)]-VC for 5 days was 4.1 ± 2.8 adducts/10(8) guanine of endogenous and 19.0 ± 4.9 adducts/10(8) guanine of exogenous εG in the liver, 8.4 ± 2.8 adducts/10(8) guanine of endogenous and 7.4 ± 0.5 adducts/10(8) guanine of exogenous εG in the lung, and 5.9 ± 3.3 adducts/10(8) guanine of endogenous and 5.7 ± 2.1 adducts/10(8) guanine of exogenous εG in the kidney (n = 4).
  • Additionally, the data from weanling rats demonstrated higher numbers of exogenous εG, with ∼4-fold higher amounts in the liver DNA of weanlings (75.9 ± 17.9 adducts/10(8) guanine) in comparison to adult rats and ∼2-fold higher amounts in the lung (15.8 ± 3.6 adducts/10(8) guanine) and kidney (12.9 ± 0.4 adducts/10(8) guanine) (n = 8).
  • The half-life of εG was found to be 150 days in the liver and lung and 75 days in the kidney, suggesting little or no active repair of this promutagenic adduct.

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. GUANINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Biodegradation. 2003 Aug;14(4):275-83 [12948057.001]
  • [Cites] Regul Toxicol Pharmacol. 2003 Feb;37(1):105-32 [12662914.001]
  • [Cites] J Mass Spectrom. 1996 Nov;31(11):1271-6 [8946734.001]
  • [Cites] Gut. 1996 Aug;39(2):312-8 [8977349.001]
  • [Cites] Biochem Pharmacol. 1998 May 1;55(9):1445-52 [10076537.001]
  • [Cites] Arch Toxicol. 1998 Oct;72(10):609-21 [9851676.001]
  • [Cites] JAMA. 1974 Jul 1;229(1):53-4 [4406736.001]
  • [Cites] Lancet. 1974 Jun 29;1(7870):1316-8 [4134297.001]
  • [Cites] Int J Cancer. 1975 Oct 15;16(4):639-44 [1176210.001]
  • [Cites] Mutat Res. 1975;32(2):93-114 [765794.001]
  • [Cites] Mutat Res. 1976 Apr;40(2):85-96 [778611.001]
  • [Cites] Cancer Res. 1977 Jan;37(1):253-7 [318606.001]
  • [Cites] Biochem Pharmacol. 1979 Mar 1;28(5):589-96 [444246.001]
  • [Cites] Biochemistry. 1979 Nov 13;18(23):5177-82 [497175.001]
  • [Cites] Food Cosmet Toxicol. 1981 Jun;19(3):317-33 [7196371.001]
  • [Cites] Environ Health Perspect. 1981 Oct;41:3-29 [6800782.001]
  • [Cites] Environ Health Perspect. 1981 Oct;41:85-8 [7333246.001]
  • [Cites] Toxicol Appl Pharmacol. 1983 Mar 30;68(1):120-30 [6682580.001]
  • [Cites] Mutat Res. 1985 Nov-Dec;152(2-3):147-56 [3906388.001]
  • [Cites] IARC Sci Publ. 1986;(70):261-8 [3793177.001]
  • [Cites] Food Chem Toxicol. 1987 Feb;25(2):187-202 [3549485.001]
  • [Cites] Carcinogenesis. 1987 May;8(5):745-7 [3581434.001]
  • [Cites] Ann N Y Acad Sci. 1988;534:145-59 [3389652.001]
  • [Cites] Arch Toxicol Suppl. 1989;13:214-8 [2774932.001]
  • [Cites] Carcinogenesis. 1990 Aug;11(8):1279-85 [2387013.001]
  • [Cites] Carcinogenesis. 1990 Aug;11(8):1287-92 [2387014.001]
  • [Cites] Food Chem Toxicol. 1991 Oct;29(10):713-8 [1959825.001]
  • [Cites] Carcinogenesis. 1992 Apr;13(4):727-9 [1576725.001]
  • [Cites] Chem Res Toxicol. 1992 Jan-Feb;5(1):2-5 [1581532.001]
  • [Cites] Science. 1994 Sep 9;265(5178):1580-2 [8079172.001]
  • [Cites] Chem Res Toxicol. 1999 Dec;12(12):1240-6 [10604874.001]
  • [Cites] Mutat Res. 2000 Jan 3;464(1):77-86 [10633179.001]
  • [Cites] Environ Health Perspect. 2000 Jul;108(7):579-88 [10905993.001]
  • [Cites] Chem Res Toxicol. 2001 Mar;14(3):327-34 [11258983.001]
  • [Cites] Water Res. 2001 Sep;35(13):3063-70 [11487101.001]
  • [Cites] Biol Chem. 2002 Jun;383(6):915-21 [12222681.001]
  • [Cites] Cancer Res. 2002 Sep 15;62(18):5183-8 [12234982.001]
  • [Cites] Cancer Res. 2002 Sep 15;62(18):5189-95 [12234983.001]
  • [Cites] Cancer Detect Prev. 2002;26(4):308-12 [12430635.001]
  • [Cites] J Occup Med. 1974 Mar;16(3):150-1 [4856325.001]
  • (PMID = 20799743.001).
  • [ISSN] 1520-5010
  • [Journal-full-title] Chemical research in toxicology
  • [ISO-abbreviation] Chem. Res. Toxicol.
  • [Language] ENG
  • [Grant] United States / NIEHS NIH HHS / ES / P30 ES010126; United States / NIEHS NIH HHS / ES / R42-ES011746; United States / NIEHS NIH HHS / ES / ES007126-29; United States / NIEHS NIH HHS / ES / T32-ES07126; United States / NIEHS NIH HHS / ES / T32 ES007126; United States / NIEHS NIH HHS / ES / R42 ES011746; United States / NIEHS NIH HHS / ES / R42 ES011746-05; United States / NIEHS NIH HHS / ES / T32 ES007126-29; United States / NIEHS NIH HHS / ES / P30 ES010126-12; United States / Intramural NIH HHS / / Z99 ES999999; United States / NIEHS NIH HHS / ES / P30-ES10126; United States / NIEHS NIH HHS / ES / P42 ES005948
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carbon Isotopes; 0 / Carcinogens; 0 / DNA Adducts; 0 / N(2),3-ethenoguanine; 5Z93L87A1R / Guanine; WD06X94M2D / Vinyl Chloride
  • [Other-IDs] NLM/ NIHMS232593; NLM/ PMC3104734
  •  go-up   go-down


82. Burns C, Harrison K, Jammer B, Zuccarini D, Lafrance B: A cancer incidence and mortality study of Dow Chemical Canada Inc. manufacturing sites. Occup Med (Lond); 2005 Dec;55(8):618-24
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There were no cases of angiosarcoma of the liver.
  • These cancers were included in the 12 deaths with malignant mesothelioma at Sarnia.
  • CONCLUSION: Consistent with the earlier report, lower mortality rates were observed for the major classifications of disease and malignant neoplasms.
  • Past asbestos exposure prior to 1980 is probably a contributor to the deaths due to malignant mesothelioma but is not reflected in lung cancer mortality.

  • MedlinePlus Health Information. consumer health - Occupational Health.
  • Hazardous Substances Data Bank. ASBESTOS .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16174663.001).
  • [ISSN] 0962-7480
  • [Journal-full-title] Occupational medicine (Oxford, England)
  • [ISO-abbreviation] Occup Med (Lond)
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 1332-21-4 / Asbestos
  •  go-up   go-down


83. Al Dhaybi R, Agoumi M, Powell J, Dubois J, Kokta V: Lymphangiosarcoma complicating extensive congenital mixed vascular malformations. Lymphat Res Biol; 2010 Sep;8(3):175-9
Genetic Alliance. consumer health - Vascular Malformations.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pediatric hepatic angiosarcoma is a very rare malignant vascular tumor.
  • A few cases have shown pediatric hepatic angiosarcoma occurring on a background of preexisting vascular lesions.
  • The autopsy's pathological examination revealed a hepatic-based angiosarcoma with plurimetastatic dissemination to the spleen, lungs, peritoneum, pleura, mesenteric linings as well as the serosa of the stomach and small intestine.
  • We hypothesize that these multiple extensive mixed vascular malformations were associated with chronic lymphedema which probably predisposed to the development of the angiosarcoma in our patient.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20863270.001).
  • [ISSN] 1557-8585
  • [Journal-full-title] Lymphatic research and biology
  • [ISO-abbreviation] Lymphat Res Biol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


84. National Toxicology Program: Toxicology and carcinogenesis studies of formamide (Cas No. 75-12-7) in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser; 2008 Jul;(541):1-192
Hazardous Substances Data Bank. FORMAMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The incidences of hemangiosarcoma of the liver occurred with a positive trend in males, and the incidences were significantly increased in the 40 and 80 mg/kg groups.
  • In three independent Ames assays, formamide was not mutagenic in any of several strains of S. typhimurium tested with and without rat or hamster liver S9 activation enzymes or in E. coli strain WP uvrA pKM101 tested with and without 10% rat liver S9.
  • There was clear evidence of carcinogenic activity of formamide in male B6C3F1 mice based on increased incidences of hemangiosarcoma of the liver.
  • [MeSH-minor] Administration, Oral. Animals. Body Weight / drug effects. Bone Marrow / drug effects. Bone Marrow / pathology. Calcinosis / chemically induced. Calcinosis / pathology. Female. Hyperplasia. Liver Neoplasms / chemically induced. Liver Neoplasms / pathology. Male. Mice. Mice, Inbred Strains. Mutagenicity Tests. Rats. Rats, Inbred F344. Spleen / drug effects. Spleen / pathology. Testis / drug effects. Testis / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18716632.001).
  • [ISSN] 0888-8051
  • [Journal-full-title] National Toxicology Program technical report series
  • [ISO-abbreviation] Natl Toxicol Program Tech Rep Ser
  • [Language] eng
  • [Publication-type] Journal Article; Technical Report
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Environmental Pollutants; 0 / Formamides; 4781T907ZS / formamide
  •  go-up   go-down


85. Khalil MF, Thomas A, Aassad A, Rubin M, Taub RN: Epithelioid Angiosarcoma of the Small Intestine After Occupational Exposure to Radiation and Polyvinyl Chloride: A case Report and Review of Literature. Sarcoma; 2005;9(3-4):161-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid Angiosarcoma of the Small Intestine After Occupational Exposure to Radiation and Polyvinyl Chloride: A case Report and Review of Literature.
  • Angiosarcomas represent 1-2% of soft tissue sarcomas and most frequently occur in the subcutis.
  • They may affect internal organs, such as the heart, liver, and spleen, and only rarely do they emerge in the gastrointestinal tract.
  • The association between angiosarcomas and certain toxic chemical substances or previous external-beam radiation therapy is well documented.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18521426.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2395632
  •  go-up   go-down


86. Pusterla N, Fecteau ME, Madigan JE, Wilson WD, Magdesian KG: Acute hemoperitoneum in horses: a review of 19 cases (1992-2003). J Vet Intern Med; 2005 May-Jun;19(3):344-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The causes for the hemoperitoneum were idiopathic (8 horses), splenic hematoma with capsular tear (7), bleeding from the reproductive tract (3), multicentric hemangiosarcoma (1), and systemic amyloidosis (1).
  • Postmortem examination of the 6 nonsurvivors showed massive abdominal hemorrhage from splenic hematoma with capsular tear (2 horses), multicentric hemangiosarcoma with liver rupture (1), systemic amyloidosis with splenic hematoma and capsular tear (1), and bilateral ruptured ovarian hematomas (1).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15954549.001).
  • [ISSN] 0891-6640
  • [Journal-full-title] Journal of veterinary internal medicine
  • [ISO-abbreviation] J. Vet. Intern. Med.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


87. Meyers RL: Tumors of the liver in children. Surg Oncol; 2007 Nov;16(3):195-203
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumors of the liver in children.
  • In this review we examine the diagnosis and treatment of pediatric liver tumors- both malignant and benign.
  • The two most common malignant tumors are hepatoblastoma and hepatocellular carcinoma.
  • Other malignant liver tumors are quite rare and include biliary rhabdomyosarcoma, angiosarcoma, rhabdoid tumor, and undifferentiated sarcoma.
  • The commonly seen benign liver tumors in children are infantile hemangioma, mesenchymal hamartoma, and focal nodular hyperplasia.
  • Rare benign tumors are hepatic adenoma, which is occasionally seen in teenage girls, and teratoma which is a very rare liver tumor in infants.
  • [MeSH-major] Liver Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17714939.001).
  • [ISSN] 0960-7404
  • [Journal-full-title] Surgical oncology
  • [ISO-abbreviation] Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 69
  •  go-up   go-down


88. Husted TL, Neff G, Thomas MJ, Gross TG, Woodle ES, Buell JF: Liver transplantation for primary or metastatic sarcoma to the liver. Am J Transplant; 2006 Feb;6(2):392-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver transplantation for primary or metastatic sarcoma to the liver.
  • Sarcoma is generally a rare disease in the US, with poor survival in patients with both primary angiosarcoma and metastatic disease from sarcoma and GIST.
  • In order to determine if liver transplantation for sarcoma is a realistic option, we examined records of all patients in the US component of the Israel Penn International Transplant Tumor Registry were reviewed.
  • Those patients with liver failure from primary or metastatic liver sarcoma were evaluated.
  • 19 patients are identified having received liver transplantation after treatment for sarcoma of the liver, 6 patients with primary hepatic sarcoma and 13 patients with metastatic sarcoma of the liver.
  • Given the early recurrence of tumor and meager 1-year survival outcome, liver transplantation is a poor therapeutic choice for patients with either primary or metastatic liver sarcoma, including high-grade leiomyosarcoma (GIST) regardless of primary site or primary therapy.
  • [MeSH-major] Liver Neoplasms / surgery. Liver Transplantation. Sarcoma / surgery


89. Nazir Z, Pervez S: Malignant vascular tumors of liver in neonates. J Pediatr Surg; 2006 Jan;41(1):e49-51
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant vascular tumors of liver in neonates.
  • Malignant vascular tumors of the liver are rare in children, especially in neonates.
  • Rapid growth and appearance of pulmonary metastasis while on aggressive medical treatment suggested malignant transformation.
  • The other neonate presented with intractable ascites and liver biopsy showed histological features of angiosarcoma.
  • Ascites has rarely been reported as a presenting feature of angiosarcoma in literature.
  • To date, surgery, chemotherapy, and radiotherapy have not improved the outcome of malignant vascular tumors of liver.
  • [MeSH-major] Hemangioendothelioma / pathology. Hemangiosarcoma / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Ascites. Diagnosis, Differential. Fatal Outcome. Female. Humans. Infant, Newborn

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16410090.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


90. García-Botella A, Díez-Valladares L, Martín-Antona E, Sánchez-Pernaute A, Pérez-Aguirre E, Ortega L, Rodríguez R, Balibrea JL: Epithelioid hemangioendothelioma of the liver. J Hepatobiliary Pancreat Surg; 2006;13(2):167-71
MedlinePlus Health Information. consumer health - Liver Transplantation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid hemangioendothelioma of the liver.
  • Epithelioid hemangioendothelioma (EH) is a rare tumor of vascular origin, which occurs at sites such as soft tissues, liver, or lung, and has a highly unpredictable malignant potential.
  • It is an intermediate entity between well-differentiated hemangioma and angiosarcoma.
  • We present two cases of this rare disease in which the tumor was detected fortuitously and the definitive diagnosis was based on histological evidence.
  • Both our cases are highly illustrative of the two ways in which hepatic EH can present (nodular or diffuse) and of its diagnostic and therapeutic management.
  • Treatment was surgical resection in one patient and liver transplant in the other.
  • Although EH of the liver has a better prognosis than other hepatic neoplasms, conservative treatment is not recommended.
  • Our cases highlight the importance of a histological diagnosis to avoid it being mistaken for another entity.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / pathology. Hemangioendothelioma, Epithelioid / surgery. Liver Neoplasms / pathology. Liver Neoplasms / surgery. Liver Transplantation
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Middle Aged

  • Genetic Alliance. consumer health - Hemangioendothelioma.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16547680.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


91. Solomon GJ, Kinkhabwala MM, Akhtar M: Inflammatory myofibroblastic tumor of the liver. Arch Pathol Lab Med; 2006 Oct;130(10):1548-51
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inflammatory myofibroblastic tumor of the liver.
  • We report a case of hepatic inflammatory myofibroblastic tumor in a 26-year-old African American man who presented with right upper quadrant pain, weight loss, and fatigue during the previous year.
  • A left partial hepatectomy was performed; the preoperative differential diagnosis was for angiosarcoma and hepatocellular carcinoma.
  • The resected liver specimen showed 2 contiguous, firm, tan-white nodules that microscopically represented a proliferation of spindled myofibroblast cells set in an inflammatory and collagenized background.
  • The morphologic and immunophenotypic findings, coupled with the clinical presentation, were consistent with an inflammatory myofibroblastic tumor of the liver.
  • [MeSH-major] Liver Neoplasms / pathology. Neoplasms, Muscle Tissue / pathology
  • [MeSH-minor] Actins / metabolism. Adult. Diagnosis, Differential. Hepatectomy. Hepatomegaly / etiology. Humans. Immunohistochemistry. Immunophenotyping. Inflammation / metabolism. Inflammation / pathology. Magnetic Resonance Imaging. Male. Muscle, Smooth / metabolism

  • Genetic Alliance. consumer health - Inflammatory myofibroblastic tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17090200.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins
  •  go-up   go-down


92. Bioulac-Sage P, Laumonier H, Laurent C, Blanc JF, Balabaud C: Benign and malignant vascular tumors of the liver in adults. Semin Liver Dis; 2008 Aug;28(3):302-14
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign and malignant vascular tumors of the liver in adults.
  • Vascular tumors of the liver in adult patients include cavernous hemangioma, a common benign tumor; epithelioid hemangioendothelioma, a rare, usually low-grade malignant tumor; and angiosarcoma, a rare and very aggressive tumor.
  • All these primary mesenchymal tumors develop on a normal liver and may also affect other organs.
  • Hepatic tumors are increasingly detected incidentally due to widespread use of modern abdominal imaging techniques.
  • Therefore, reliable noninvasive characterization and differentiation of such liver tumors is of major importance for clinical practice.
  • A definitive diagnosis of epithelioid hemangioendothelioma and angiosarcoma requires histopathologic examination.
  • Liver transplantation at an early stage has greatly improved the prognosis of epithelioid hemangioendothelioma.
  • The prognosis of angiosarcoma remains dismal.
  • [MeSH-major] Liver / blood supply. Liver Neoplasms. Neoplasms, Vascular Tissue
  • [MeSH-minor] Adult. Hemangioendothelioma, Epithelioid / pathology. Hemangioendothelioma, Epithelioid / therapy. Hemangioma, Cavernous / pathology. Hemangioma, Cavernous / therapy. Hemangiosarcoma / pathology. Hemangiosarcoma / therapy. Hepatic Stellate Cells / pathology. Humans. Sarcoma, Kaposi / pathology. Sarcoma, Kaposi / therapy. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18814083.001).
  • [ISSN] 0272-8087
  • [Journal-full-title] Seminars in liver disease
  • [ISO-abbreviation] Semin. Liver Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 45
  •  go-up   go-down


93. Kimura T, Mukai M, Kaneko Y, Hirakata M, Okamoto S, Sakamoto M, Okada Y, Ikeda Y: Unusual hemangioendothelioma of the liver with epithelioid morphology associated with marked eosinophilia: autopsy case. Pathol Int; 2006 Nov;56(11):694-701
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual hemangioendothelioma of the liver with epithelioid morphology associated with marked eosinophilia: autopsy case.
  • Biopsy and autopsy revealed an unusual epithelioid vascular tumor in the liver, which is histologically distinct from epithelioid hemangioma, epithelioid hemangioendothelioma, or epithelioid angiosarcoma.
  • Organs other than the liver, for example the testes and bone, were also involved.
  • This tumor should be considered in the differential diagnosis of severe eosinophilia.
  • [MeSH-major] Eosinophilia / pathology. Hemangioendothelioma, Epithelioid / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Fatal Outcome. Hepatomegaly / complications. Hepatomegaly / pathology. Humans. Interleukin-5 / blood. Male. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Hemangioendothelioma.
  • MedlinePlus Health Information. consumer health - Eosinophilic Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17040294.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Interleukin-5
  •  go-up   go-down


94. van Kampen RJ, Erdkamp FL, Peters FP: Thorium dioxide-related haemangiosarcoma of the liver. Neth J Med; 2007 Sep;65(8):279-82
Hazardous Substances Data Bank. THORIUM DIOXIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thorium dioxide-related haemangiosarcoma of the liver.
  • Rare tumours of the liver are occasionally seen; thorium dioxide-related haemangiosarcoma of the liver, with an estimated frequency of 0.14 to 0.25 per million in the normal population, is one of these.
  • Causes, epidemiology and pathobiology are described related to a clinical case of angiosarcoma.
  • A differentiation of hepatic tumours with imaging techniques is presented.
  • [MeSH-major] Hemangiosarcoma / chemically induced. Liver Neoplasms / chemically induced. Thorium Dioxide / adverse effects

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Neth J Med. 2007 Sep;65(8):276-8 [17890785.001]
  • (PMID = 17890786.001).
  • [ISSN] 0300-2977
  • [Journal-full-title] The Netherlands journal of medicine
  • [ISO-abbreviation] Neth J Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Contrast Media; 9XA7X17UQC / Thorium Dioxide
  • [Number-of-references] 18
  •  go-up   go-down


95. Bismuth B, Castel H, Boleslawski E, Buob D, Lambert M, Declerck N, Canva V, Zafrani ES, Mathurin P, Pruvot FR, Dharancy S: Primary sarcoma of the liver and transplantation: a case study and literature review. Rare Tumors; 2009;1(2):e31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary sarcoma of the liver and transplantation: a case study and literature review.
  • Primary sarcomas of the liver are rare tumors and their diagnosis is difficult to assess, particularly on percutaneous liver biopsy.
  • Epithelioid hemangioendothelioma (EHE) is an infrequent indication for liver transplantation, and angiosarcoma (AS) is a widely recognized contraindication because of its poor prognosis.
  • We report the case of a young woman who underwent liver transplantation (LT) for an infiltrative hepatic tumor with several features suggestive of EHE, although the analysis of the native liver revealed AS.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21139910.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994467
  • [Keywords] NOTNLM ; angiosarcoma / epithelioid hemangioendothelioma / liver transplantation
  •  go-up   go-down


96. Hertl M, Cosimi AB: Liver transplantation for malignancy. Oncologist; 2005 Apr;10(4):269-81
MedlinePlus Health Information. consumer health - Liver Transplantation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver transplantation for malignancy.
  • Liver transplantation for hepatic malignancies has emerged from an exotic and desperate approach to a well-documented and proven treatment modality for these unfortunate patients.
  • Currently, <10% of all liver transplants performed are for hepatocellular cancer (HCC).
  • Similarly, liver transplantation for HCC in the adult population yields good results for patients whose tumor masses do not exceed the Milan criteria.
  • Epitheloid hemangioendothelioma is also an appropriate indication for liver transplantation, unlike angiosarcoma.
  • Metastatic liver disease is not an indication for liver transplantation, with the exception of cases in which the primary is a neuroendocrine tumor, for which liver transplantation can result in long-term survival and even cure in a number of patients.
  • And finally, while gallbladder cancers are never an indication for liver transplantation, rare cases of cholangiocellular cancer might qualify if aggressive combination therapies, including chemotherapy and radiotherapy followed by OLT, are carried through.
  • Survival in these selected patients can approach that for patients with cholestatic liver disease.
  • [MeSH-major] Bile Duct Neoplasms / surgery. Carcinoma, Hepatocellular / surgery. Liver Neoplasms / surgery. Liver Transplantation
  • [MeSH-minor] Cholangiocarcinoma / mortality. Cholangiocarcinoma / pathology. Cholangiocarcinoma / surgery. Hemangioendothelioma, Epithelioid / mortality. Hemangioendothelioma, Epithelioid / pathology. Hemangioendothelioma, Epithelioid / surgery. Hepatoblastoma / mortality. Hepatoblastoma / pathology. Hepatoblastoma / surgery. Humans. Medical Oncology / trends. Neoplasm Metastasis. Patient Selection. Survival Rate. Treatment Outcome. Waiting Lists

  • Genetic Alliance. consumer health - Transplantation.
  • MedlinePlus Health Information. consumer health - Bile Duct Cancer.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15821247.001).
  • [ISSN] 1083-7159
  • [Journal-full-title] The oncologist
  • [ISO-abbreviation] Oncologist
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 62
  •  go-up   go-down


97. Hoti E, Adam R: Liver transplantation for primary and metastatic liver cancers. Transpl Int; 2008 Dec;21(12):1107-17
MedlinePlus Health Information. consumer health - Liver Transplantation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver transplantation for primary and metastatic liver cancers.
  • Liver transplantation for hepatic malignancies has emerged as a well-documented and proven treatment modality.
  • Currently, 15% of all liver transplants performed are for hepatocellular carcinoma (HCC).
  • There is no controversy about the fact that liver transplantation for HCC in the adult population yields good results for patients whose tumour masses do not exceed the Milan criteria.
  • In patients with small HCC at an early stage and preserved liver function, liver resection provides an alternative to transplant.
  • Liver resection may offer similar survival results to orthotopic liver transplantation (OLT) in the short term, and does not carry the long-term effects of immunosuppression; however, long-term and disease-free survival favours liver transplantation.
  • Survival rate in these selected patients can approach that of patients with cholestatic liver disease, and the role of transplantation now requires re-evaluation.
  • Epithelioid hemangioendothelioma is also an appropriate indication for liver transplantation, even in the presence of extrahepatic metastases, unlike angiosarcoma which is associated with a very poor survival and considered as a contraindication.
  • And finally for metastatic liver disease from neuroendocrine tumours, liver transplantation can result in long-term survival and even cure in well selected patients.
  • Conversely, the value of transplantation for colorectal liver metastases (currently a contraindication) requires further evaluation by well-designed trials.
  • [MeSH-major] Liver Neoplasms / pathology. Liver Neoplasms / surgery. Liver Transplantation
  • [MeSH-minor] Bile Duct Neoplasms / surgery. Carcinoma, Hepatocellular / pathology. Carcinoma, Hepatocellular / surgery. Cholangiocarcinoma / surgery. Colorectal Neoplasms / pathology. Hemangioendothelioma / surgery. Hemangiosarcoma / surgery. Humans. Neoplasm Metastasis. Neoplasm Staging. Neuroendocrine Tumors / surgery. Survival Analysis. Survivors. Treatment Outcome

  • Genetic Alliance. consumer health - Transplantation.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18713148.001).
  • [ISSN] 0934-0874
  • [Journal-full-title] Transplant international : official journal of the European Society for Organ Transplantation
  • [ISO-abbreviation] Transpl. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 75
  •  go-up   go-down


98. Weitz J, Klimstra DS, Cymes K, Jarnagin WR, D'Angelica M, La Quaglia MP, Fong Y, Brennan MF, Blumgart LH, Dematteo RP: Management of primary liver sarcomas. Cancer; 2007 Apr 1;109(7):1391-6
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of primary liver sarcomas.
  • BACKGROUND: Primary hepatic sarcoma is a rare entity.
  • METHODS: Between January 1981 and December 2004, 30 patients with primary sarcoma of the liver and 5 patients with primary carcinosarcoma of the liver were treated.
  • RESULTS: Of the 30 patients with primary hepatic sarcoma (10 epithelioid hemangioendothelioma, 5 embryonal sarcoma, 5 angiosarcoma, 3 solitary fibrous tumor, and 7 other types), 11 underwent R0-resection and had a 5-year disease-specific survival of 64%.
  • In the group of 7 patients with high-grade sarcomas who underwent R0-resection, both patients with angiosarcoma died within 11 months, whereas the 5 patients with embryonal sarcoma had a 5-year disease-free and disease-specific survival of 80%.
  • The prognosis for patients with primary carcinosarcoma of the liver was poor, with all but 1 patient dying within a year and no 3-year survivors.
  • CONCLUSIONS: The outcome of patients with primary hepatic sarcoma depends primarily on tumor histology and the ability to achieve complete tumor resection.
  • [MeSH-major] Liver Neoplasms / therapy. Sarcoma / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinosarcoma / therapy. Child. Female. Fibrosarcoma / therapy. Hemangioendothelioma, Epithelioid / therapy. Hemangiosarcoma / therapy. Humans. Leiomyosarcoma / therapy. Male. Middle Aged. Prognosis. Prospective Studies. Survival Rate. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 American Cancer Society.
  • (PMID = 17315167.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


99. Yamamoto Y, Chikawa J, Uegaki Y, Usuda N, Kuwahara Y, Fukumoto M: Histological type of Thorotrast-induced liver tumors associated with the translocation of deposited radionuclides. Cancer Sci; 2010 Feb;101(2):336-40
Hazardous Substances Data Bank. THORIUM, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Histological type of Thorotrast-induced liver tumors associated with the translocation of deposited radionuclides.
  • Exposure to internally deposited radionuclides is known to induce malignant tumors of various histological types.
  • Thorotrast is known to induce liver tumors, particularly intrahepatic cholangiocarcinoma (ICC) and angiosarcoma (AS), decades after injection.
  • Autoradiography and X-ray fluorescence spectrometry (XRF) were carried out on non-tumorous liver sections from Thorotrast-induced ICC (T-ICC) and Thorotrast-induced AS (T-AS).
  • Autoradiography revealed that the slope of the regression line of the number of alpha tracks for the amount of deposited Thorium ((232)Th) was higher in non-tumorous parts of the liver with T-ICC than those with T-AS.
  • XRF showed that the intensity ratio of Radium (Ra) to Thorium (Th) in non-tumorous liver tissue with T-ICC was significantly higher than that with T-AS.
  • These suggest that the metabolic behavior of radionuclides such as relocation and excretion, as well as the content of deposited radionuclides, is a major factor in determining the histological type of Thorotrast-induced liver tumors.
  • [MeSH-major] Liver Neoplasms / etiology. Radium / pharmacokinetics. Thorium / pharmacokinetics. Thorium Dioxide / adverse effects
  • [MeSH-minor] Adult. Alpha Particles. Autoradiography. Biological Transport. Humans. Liver / metabolism. Radiation Dosage. Spectrometry, X-Ray Emission

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • Hazardous Substances Data Bank. THORIUM DIOXIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19917057.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 60YU5MIG9W / Thorium; 9XA7X17UQC / Thorium Dioxide; W90AYD6R3Q / Radium
  •  go-up   go-down


100. O'Brien RT: Improved detection of metastatic hepatic hemangiosarcoma nodules with contrast ultrasound in three dogs. Vet Radiol Ultrasound; 2007 Mar-Apr;48(2):146-8
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Improved detection of metastatic hepatic hemangiosarcoma nodules with contrast ultrasound in three dogs.
  • Three dogs with a splenic hemangiosarcoma were imaged with conventional gray-scale ultrasound and no lesions were identified in the liver.
  • After administration of intravenous ultrasound contrast medium (Definity) small, poorly enhanced, hypoechoic nodules were identified in the liver in each dog.
  • The spleen and liver lesions were identified at surgery and the dogs underwent splenectomy and nodule biopsy.
  • All lesions were identified histologically as hemangiosarcoma.
  • These preliminary results suggest that contrast ultrasound may result in improved detectability of metastatic hepatic hemangiosarcoma.
  • [MeSH-major] Hemangiosarcoma / veterinary. Liver Neoplasms / veterinary. Splenic Neoplasms / veterinary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17385374.001).
  • [ISSN] 1058-8183
  • [Journal-full-title] Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
  • [ISO-abbreviation] Vet Radiol Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down






Advertisement