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Items 1 to 43 of about 43
1. Tse LF, Ek ET, Slavin JL, Schlicht SM, Choong PF: Intraosseous angiosarcoma with secondary aneurysmal bone cysts presenting as an elusive diagnostic challenge. Int Semin Surg Oncol; 2008;5:10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraosseous angiosarcoma with secondary aneurysmal bone cysts presenting as an elusive diagnostic challenge.
  • Angiosarcoma of bone is an exceedingly rare primary bone malignancy that can present as an aggressive osteolytic lesion.
  • Histological diagnosis can be extremely challenging, as the pathological features often resemble that of aneurysmal bone cysts.
  • We report an interesting and peculiar case of an intraosseous angiosarcoma that presented as a diagnostic dilemma and discuss the relevant radiological and pathologic findings.

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  • (PMID = 18492283.001).
  • [ISSN] 1477-7800
  • [Journal-full-title] International seminars in surgical oncology : ISSO
  • [ISO-abbreviation] Int Semin Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2413251
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2. Mittal S, Goswami C, Kanoria N, Bhattacharya A: Post-irradiation angiosarcoma of bone. J Cancer Res Ther; 2007 Apr-Jun;3(2):96-9
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  • [Title] Post-irradiation angiosarcoma of bone.
  • We report a rare case of high-grade epithelioid angiosarcoma of upper end of right humerus in a 67-year-old male occurring ten years following irradiation for giant cell tumor of the same anatomical site.
  • He underwent excision of affected part of humerus followed by cemented hemiarthroplasty and bone grafting.
  • After initial histopathological diagnostic dilemma the final report was given as post-radiation angiosarcoma.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Humerus. Neoplasms, Radiation-Induced / diagnosis
  • [MeSH-minor] Aged. Humans. Male. Neoplasm Recurrence, Local / diagnosis. Treatment Outcome

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  • (PMID = 17998731.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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3. Kudva R, Perveen S, Janardhana A: Primary epithelioid angiosarcoma of bone: a case report with immunohistochemical study. Indian J Pathol Microbiol; 2010 Oct-Dec;53(4):811-3
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  • [Title] Primary epithelioid angiosarcoma of bone: a case report with immunohistochemical study.
  • Primary malignant vascular tumors of the bone are exceedingly rare and represent <1% of primary malignant bone tumors.
  • Angiosarcoma is a malignant mesenchymal neoplasm in which the neoplastic cells demonstrate endothelial differentiation.
  • Epithelioid angiosarcoma (EA) is a rare variant of angiosarcoma that is characterized by large cells with an epithelioid morphology.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Hemangiosarcoma / diagnosis. Hemangiosarcoma / pathology. Sarcoma / diagnosis. Sarcoma / pathology. Tibia / pathology

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  • (PMID = 21045426.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Antineoplastic Agents
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4. Hadidy A, Alsharif A, Sheikh-Ali R, Abukhalaf M, Awidi A, Abukaraki A, Nimri C, Omari A: Odontogenic myxofibroma synchronous with primary angiosarcoma of the spleen. Br J Radiol; 2010 Jan;83(985):e10-3
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  • [Title] Odontogenic myxofibroma synchronous with primary angiosarcoma of the spleen.
  • Odontogenic myxofibroma of the temporomandibular joint (TMJ) is a rare tumour; moreover, primary splenic angiosarcoma (PAS) in paediatric patients is extremely rare.
  • The TMJ swelling proved to be odontogenic myxofibroma and the abdominal pain was a result of primary splenic angiosarcoma with hepatic metastasis.
  • We report for the first time the synchronous presentation of PAS and odontogenic myxofibroma in a paediatric patient, and we describe the radiological features along with the histological diagnosis and clinical outcome.
  • [MeSH-major] Fibroma / diagnosis. Hemangiosarcoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Odontogenic Tumors / diagnosis. Splenic Neoplasms / diagnosis. Temporomandibular Joint Disorders / diagnosis
  • [MeSH-minor] Adolescent. Bone Neoplasms / secondary. Diagnosis, Differential. Fatal Outcome. Humans. Liver Neoplasms / secondary. Male

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  • (PMID = 20139242.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3487256
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5. Scholsem M, Raket D, Flandroy P, Sciot R, Deprez M: Primary temporal bone angiosarcoma: a case report. J Neurooncol; 2005 Nov;75(2):121-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary temporal bone angiosarcoma: a case report.
  • We present a rare case of temporal bone angiosarcoma diagnosed in a 26-year-old female patient at 36 week of pregnancy.
  • Cranial imaging studies showed a 7 x 5 x 4 cm hypervascularized mass located in the left middle fossa with lysis of the temporal bone and extension to the subcutis.
  • Pathological findings were those of a poorly differentiated, highly malignant sarcoma with a large epitheloid component and immunohistochemical evidence of endothelial differentiation (CD31, Factor VIII related antigen, CD34), consistent with an angiosarcoma with epitheloid features.
  • Despite an initial good response, she died with metastatic disease 26 months after diagnosis.
  • We present a rare case of primary temporal bone angiosarcoma and report our experience with a multimode therapeutic approach combining surgery, radiotherapy and chemotherapy.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Skull Neoplasms / diagnosis. Skull Neoplasms / pathology. Temporal Bone
  • [MeSH-minor] Adult. Angiography. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / secondary. Combined Modality Therapy. Fatal Outcome. Female. Follow-Up Studies. Humans. Lung Neoplasms / secondary. Pregnancy. Pregnancy Trimester, Third. Tomography, X-Ray Computed

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  • (PMID = 16132518.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Mitsuhashi T, Shimizu Y, Ban S, Ogawa F, Hirose T, Tanaka J, Shimizu M: Multicentric contiguous variant of epithelioid angiosarcoma of the bone. A rare variant showing angiotropic spread. Ann Diagn Pathol; 2005 Feb;9(1):33-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multicentric contiguous variant of epithelioid angiosarcoma of the bone. A rare variant showing angiotropic spread.
  • Epithelioid angiosarcoma of the bone is a rare tumor and is a diagnostic challenge.
  • The initial diagnosis of a tibial biopsy was poorly differentiated adenocarcinoma.
  • Multicentric epithelioid angiosarcoma of the bone is a pitfall in pathological diagnoses, especially if a strong radiological impression of metastatic carcinoma is provided.
  • [MeSH-major] Bone Neoplasms / pathology. Epithelioid Cells / pathology. Hemangiosarcoma / secondary. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Antigens, CD31 / analysis. Biomarkers, Tumor / analysis. Biopsy. Diagnosis, Differential. Fatal Outcome. Humans. Immunohistochemistry. Keratins / analysis. Male. Middle Aged. Neoplasm Invasiveness / pathology. Tibia / pathology. Vimentin / analysis. von Willebrand Factor / analysis

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  • (PMID = 15692948.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Biomarkers, Tumor; 0 / Vimentin; 0 / von Willebrand Factor; 68238-35-7 / Keratins
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7. Zver S, Bracko M, Andoljsek D: Primary bone angiosarcoma in a patient with Gaucher disease. Int J Hematol; 2010 Sep;92(2):374-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary bone angiosarcoma in a patient with Gaucher disease.
  • After a pathological fracture of the painful part of the leg, it became evident that the patient suffered from primary bone angiosarcoma.
  • [MeSH-major] Bone Neoplasms / diagnosis. Gaucher Disease / complications. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Fatal Outcome. Fractures, Bone. Humans. Leg / pathology. Middle Aged


8. Mignogna C, Simonetti S, Galloro G, Magno L, De Cecio R, Insabato L: Duodenal epithelioid angiosarcoma: immunohistochemical and clinical findings. A case report. Tumori; 2007 Nov-Dec;93(6):619-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Duodenal epithelioid angiosarcoma: immunohistochemical and clinical findings. A case report.
  • Angiosarcomas mainly involve skin and soft tissue and rarely occur in breast, liver, bone, and spleen.
  • A duodenal reddish polypoid lesion was found, which on microscopic examination turned out to be an epithelioid angiosarcoma.
  • The immunohistochemical features of the lesion supported this diagnosis.
  • The patient died eight months after the diagnosis.
  • Epithelioid angiosarcoma is an aggressive variant of angiosarcoma and must be considered in the differential diagnosis of gastrointestinal tumors.
  • [MeSH-major] Duodenal Neoplasms / pathology. Hemangioendothelioma, Epithelioid / pathology. Hemangiosarcoma / pathology

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  • (PMID = 18338501.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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9. Saglik Y, Yildiz Y, Atalar H, Basarir K: Primary angiosarcoma of the fibula : a case report. Acta Orthop Belg; 2007 Dec;73(6):799-803
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  • [Title] Primary angiosarcoma of the fibula : a case report.
  • Primary vascular neoplasms of bone are rare and have a poor prognosis.
  • Angiosarcoma of bone originates in vascular endothelial cells within bone tissue.
  • Patients may present with unifocal or multifocal osseous disease.
  • Here we present a 72-year-old male patient who had primary angiosarcoma of the fibula.
  • [MeSH-major] Bone Neoplasms / diagnosis. Fibula. Hemangiosarcoma / diagnosis

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  • (PMID = 18260498.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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10. Drexler M, Dolkart O, Amar E, Pritsch T, Dekel S: Late recurrent hemarthrosis following knee arthroplasty associated with epithelioid angiosarcoma of bone. Knee; 2010 Oct;17(5):365-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Late recurrent hemarthrosis following knee arthroplasty associated with epithelioid angiosarcoma of bone.
  • We report a case of recurrent hemarthrosis 1 year following total knee arthroplasty in a patient with no bleeding diathesis, the hemarthrosis was found to be related to, and led to the diagnosis of high grade sarcoma of the proximal tibia.
  • Sarcoma developing in association with a metallic orthopedic prosthesis or hardware is an uncommon, but well-recognized complication.
  • [MeSH-major] Arthroplasty, Replacement, Knee. Bone Neoplasms / diagnosis. Hemarthrosis / etiology. Osteosarcoma / diagnosis. Postoperative Complications

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  • [Copyright] Copyright 2009 Elsevier B.V. All rights reserved.
  • (PMID = 19945286.001).
  • [ISSN] 1873-5800
  • [Journal-full-title] The Knee
  • [ISO-abbreviation] Knee
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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11. Hindersin S, Schubert O, Cohnen M, Felsberg J, Schipper J, Hoffmann TK: [Angiosarcoma of the temporal bone]. Laryngorhinootologie; 2008 May;87(5):345-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiosarcoma of the temporal bone].
  • Angiosarcoma of the temporal bone is an extremely rare malignant tumor, which originates from vascular endothelium.
  • After subtotal mastoidectomy histological examination revealed an angiosarcoma of the mastoid.
  • [MeSH-major] Hemangiosarcoma / surgery. Skull Neoplasms / surgery. Temporal Bone / surgery
  • [MeSH-minor] Diagnosis, Differential. Disease Progression. Facial Paralysis / etiology. Fatal Outcome. Female. Hearing Loss, Sudden / etiology. Humans. Mastoid / pathology. Mastoid / surgery. Meninges / pathology. Middle Aged. Neck Dissection. Neoplasm Invasiveness. Neoplasm Staging

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  • (PMID = 18509895.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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12. Hsu JT, Chen HM, Lin CY, Yeh CN, Hwang TL, Jan YY, Chen MF: Primary angiosarcoma of the spleen. J Surg Oncol; 2005 Dec 15;92(4):312-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the spleen.
  • BACKGROUND AND OBJECTIVES: Primary splenic angiosarcoma is a very rare and aggressive neoplasm with a high metastatic rate and dismal prognosis.
  • METHODS: The records of all cases of primary splenic angiosarcoma treated at Chang Gung Memorial Hospital from April 1991 to July 2004 were retrospectively reviewed.
  • Three patients had distant metastasis to the liver (n = 2), bone (n = 1), bone marrow (n = 1), and small bowel (n = 1) at diagnosis.
  • Liver (n = 3), bone (n = 1), and bone marrow (n = 1) metastases were found in four patients after initial therapy.
  • CONCLUSIONS: The clinical presentations of splenic angiosarcoma were similar to those of previous reports apart from the higher rate of splenomegaly observed in this study.
  • [MeSH-major] Hemangiosarcoma. Splenic Neoplasms

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  • [Copyright] 2005 Wiley-Liss, Inc.
  • (PMID = 16299797.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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13. Tsolakis I, Lampropoulos G, Zolota V, Papadoulas S, Christeas N: Aortic angiosarcoma with cutaneous metastases. Vascular; 2009 May-Jun;17(3):176-80
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  • [Title] Aortic angiosarcoma with cutaneous metastases.
  • The diagnosis of aortic angiosarcoma is usually confirmed by postoperative histopathologic examination or postmortem study.
  • We present a case of primary aortic angiosarcoma presenting with intermittent claudication and radiologic findings of aortoiliac atherosclerotic disease treated initially with stenting; lower extremity embolic skin metastases developed during follow-up that prompted resection of the aortic bifurcation and restoration of the arterial continuity with a bypass.
  • [MeSH-major] Aortic Diseases / diagnostic imaging. Foot Diseases / etiology. Hemangiosarcoma / diagnostic imaging. Skin Neoplasms / secondary
  • [MeSH-minor] Angiography, Digital Subtraction. Bone Neoplasms / diagnostic imaging. Bone Neoplasms / secondary. Female. Humans. Middle Aged. Tibial Arteries / diagnostic imaging. Tibial Arteries / pathology. Treatment Outcome. Uterine Neoplasms / diagnostic imaging. Uterine Neoplasms / secondary

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  • (PMID = 19476753.001).
  • [ISSN] 1708-5381
  • [Journal-full-title] Vascular
  • [ISO-abbreviation] Vascular
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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14. Smith RA, Dzugan SA, Rafique S, Lucas M: Angiosarcoma replacing bone marrow--a case report. J Miss State Med Assoc; 2005 Feb;46(2):35-6

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  • [Title] Angiosarcoma replacing bone marrow--a case report.
  • Diffuse marrow replacement by mesodermal origin sarcoma is rare in adults, and angiosarcoma replacing bone marrow is a very rare neoplasm.
  • METHODS: A case of bone marrow replacement by angiosarcoma in a 54-year-old African American man is described with a review of pertinent literature.
  • RESULTS: Histopathologic exam of trephine bone marrow biopsy revealed replacement of marrow spaces by a proliferating highly vascular malignant neoplasm with features of high-grade angiosarcoma.
  • CONCLUSION: Few reports in the literature describe angiosarcomatosis of the bone marrow.
  • It is important to recognize this unusual presentation to avoid confusion with other more common bone marrow replacing entities and to promote recognition that more efficacious treatment is needed.
  • [MeSH-major] Bone Marrow Neoplasms / diagnosis. Hemangiosarcoma / diagnosis

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  • (PMID = 15816231.001).
  • [ISSN] 0026-6396
  • [Journal-full-title] Journal of the Mississippi State Medical Association
  • [ISO-abbreviation] J Miss State Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Sanchez-Mejia RO, Ojemann SG, Simko J, Chaudhary UB, Levy J, Lawton MT: Sacral epithelioid angiosarcoma associated with a bleeding diathesis and spinal epidural hematoma: case report. J Neurosurg Spine; 2006 Mar;4(3):246-50
Hazardous Substances Data Bank. IFOSFAMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sacral epithelioid angiosarcoma associated with a bleeding diathesis and spinal epidural hematoma: case report.
  • Epithelioid angiosarcoma of bone is a rare, high-grade lesion that is highly vascular and can be associated with a bleeding diathesis.
  • The authors report the case of a rare occurrence of a primary sacral epithelioid angiosarcoma associated with a large epidural hematoma and a severe bleeding diathesis.
  • This case represents the first report of a primary epithelioid angiosarcoma in the sacrum and emphasizes that the coagulopathy seen in angiosarcoma is also a feature of this epithelioid variant.
  • [MeSH-major] Bone Neoplasms / complications. Hemangiosarcoma / complications

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  • (PMID = 16572625.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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16. Marthya A, Patinharayil G, Puthezeth K, Sreedharan S, Kumar A, Kumaran CM: Multicentric epithelioid angiosarcoma of the spine: a case report of a rare bone tumor. Spine J; 2007 Nov-Dec;7(6):716-9
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  • [Title] Multicentric epithelioid angiosarcoma of the spine: a case report of a rare bone tumor.
  • BACKGROUND CONTEXT: Epithelioid angiosarcoma (EA) is a high-grade sarcoma of vascular origin.
  • EA is a rare variant of angiosarcoma.
  • EA has been reported in sites like skin thyroid, adrenal gland, soft tissue, and rarely in bone.
  • The authors point out the need for immunohistochemical evaluation after careful histological analysis for vascular differentiation for an accurate diagnosis of vascular bone tumors with epithelioid features so that an erroneous diagnosis of metastatic carcinoma can be avoided.
  • EA occurs rarely in bone.
  • These types of lesions are a definite diagnostic challenge in bone biopsy.
  • A conservative surgical approach with a radical course of megavoltage radiotherapy could yield a good result in EA of bone.
  • Careful histologic and immunohistochemical analysis will clinch the diagnosis.
  • Even though rare, we stress the importance to be aware of the existence of this tumor, which is essential for correct diagnosis.
  • [MeSH-major] Bone Neoplasms / pathology. Epithelioid Cells / pathology. Hemangiosarcoma / pathology. Magnetic Resonance Imaging. Thoracic Vertebrae / pathology

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  • (PMID = 17998131.001).
  • [ISSN] 1529-9430
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Cheshier SH, Bababeygy SR, Higgins D, Parsonnet J, Huhn SL: Cerebral myiasis associated with angiosarcoma of the scalp: case report. Neurosurgery; 2007 Jul;61(1):E167; discussion E167
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  • [Title] Cerebral myiasis associated with angiosarcoma of the scalp: case report.
  • Examination revealed a 15 x 17 cm frontal bone defect with eroded frontal dura, exposed cortex, and massive cortical maggot infestation.
  • Biopsy of the scalp and cranium revealed angiosarcoma, for which operative treatment was refused.
  • [MeSH-major] Brain Diseases / parasitology. Brain Diseases / therapy. Myiasis / diagnosis. Myiasis / parasitology. Myiasis / therapy. Scalp / parasitology. Skin Neoplasms / parasitology

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  • (PMID = 17621006.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Abraham JA, Hornicek FJ, Kaufman AM, Harmon DC, Springfield DS, Raskin KA, Mankin HJ, Kirsch DG, Rosenberg AE, Nielsen GP, Desphpande V, Suit HD, DeLaney TF, Yoon SS: Treatment and outcome of 82 patients with angiosarcoma. Ann Surg Oncol; 2007 Jun;14(6):1953-67
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  • [Title] Treatment and outcome of 82 patients with angiosarcoma.
  • METHODS: Patients with a diagnosis of angiosarcoma treated at our institution between 1980 and 2006 were analyzed for patient demographics, tumor characteristics, multimodality treatment, and outcomes.
  • Tumors were located throughout the body: 32 cutaneous, 22 deep soft tissues or organs, 10 radiation or lymphedema field, 8 bone, and 7 nonirradiated breast.
  • [MeSH-major] Hemangiosarcoma / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Bone Neoplasms / pathology. Bone Neoplasms / surgery. Breast Neoplasms / pathology. Breast Neoplasms / surgery. Chemotherapy, Adjuvant. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoadjuvant Therapy. Neoplasm Staging. Neoplasms, Radiation-Induced / pathology. Neoplasms, Radiation-Induced / surgery. Palliative Care. Radiotherapy, Adjuvant. Retrospective Studies. Skin Neoplasms / pathology. Skin Neoplasms / surgery. Soft Tissue Neoplasms / pathology. Soft Tissue Neoplasms / surgery. Survival Rate. Treatment Outcome

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  • (PMID = 17356953.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / 5K12CA87723-03
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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19. Kamo R, Ishina K, Hirata C, Doi K, Nakanishi T, Harada T, Ishii M: A case of ileoileal intussusception caused by metastatic pedunculated tumor of cutaneous angiosarcoma. J Dermatol; 2005 Aug;32(8):638-40
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  • [Title] A case of ileoileal intussusception caused by metastatic pedunculated tumor of cutaneous angiosarcoma.
  • Cutaneous angiosarcoma is a rare aggressive vascular tumor that occurs in elderly patients and is usually located on the head and face.
  • Metastases often develop in the cervical lymph nodes, lungs, bone, liver and spleen.
  • There have been no reports of ileoileal intussusception due to metastatic tumor from cutaneous angiosarcoma.
  • We reported a case of cutaneous angiosarcoma in a 67-year-old Japanese male accompanied with ileoileal intussusception due to metastatic angiosarcoma.
  • We assume that the metastatic tumor in the small intestine was metastasized hematogeneously from cutaneous angiosarcoma, resulting in the formation of nodules and the rapid growth of a pedunculated tumor as a forerunner of the ileoileal intessusception.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Ileal Neoplasms / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Ileal Diseases / etiology. Intussusception / etiology. Male. Scalp

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  • (PMID = 16334863.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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20. Maluf D, Cotterell A, Clark B, Stravitz T, Kauffman HM, Fisher RA: Hepatic angiosarcoma and liver transplantation: case report and literature review. Transplant Proc; 2005 Jun;37(5):2195-9
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  • [Title] Hepatic angiosarcoma and liver transplantation: case report and literature review.
  • Hepatic angiosarcoma is a rare malignant vascular tumor that accounts for up to 2% of all primary liver tumors.
  • Accurate diagnosis of this tumor is difficult, especially if the patient has no history of exposure to specific carcinogens including thorotrast, arsenicals, and vinyl chloride monomer.
  • Diagnosis of diffuse angiosarcoma by means of liver biopsy has been reported as treacherous and nondiagnostic.
  • High grade diffuse angiosarcoma was diagnosed in the explanted liver.
  • The patient developed bone metastases at 8 months and is alive 1 year posttransplantation.
  • Diffuse liver tissue infiltration seen pretransplant on CT scan or MRI, suggesting the possibility of diffuse liver lesions (HCC, angiosarcoma, etc) must be fully investigated with all techniques available including multiple open liver biopsies to avoid the sacrifice of a liver allograft in these patients.
  • [MeSH-major] Hemangiosarcoma / pathology. Hemangiosarcoma / surgery. Liver Neoplasms / pathology. Liver Neoplasms / surgery. Liver Transplantation

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  • (PMID = 15964377.001).
  • [ISSN] 0041-1345
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
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21. Kawasaki T, Hen K, Satoh E, Kanno H, Watanabe K, Hasegawa H: Oral presentation of epithelioid angiosarcoma with first sign in the scapula: report of a case and review of the literature. Fukushima J Med Sci; 2005 Dec;51(2):77-85
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  • [Title] Oral presentation of epithelioid angiosarcoma with first sign in the scapula: report of a case and review of the literature.
  • Occurrence of a primary or metastatic angiosarcoma in the oral cavity is extremely rare.
  • The term "epithelioid angiosarcoma" (EA) has been used to designate a morphological variant of angiosarcoma characterized by poorly differentiated epithelial-like cells arranged in carcinoma-like fashion, but which still forms identifiable vascular channels.
  • In order to confirm the diagnosis, immunohistochemical examinations were performed.
  • The final diagnosis was EA.
  • The patient died of multiple metastases shortly after the final diagnosis, implying an aggressive clinical course.
  • This case showed that it was essential to use the vascular markers, such as FVIII-Rag and CD34, for a correct histological diagnosis of EA.
  • [MeSH-major] Bone Neoplasms / pathology. Hemangiosarcoma / pathology. Mouth Neoplasms / pathology. Scapula

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  • (PMID = 16555628.001).
  • [ISSN] 0016-2590
  • [Journal-full-title] Fukushima journal of medical science
  • [ISO-abbreviation] Fukushima J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 12
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22. Tada Y, Takiguchi Y, Terada J, Yoshida T, Shinozaki A, Sakao S, Kasahara Y, Kurosu K, Tanabe N, Tatsumi K, Hiroshima K, Kuriyama T: [A case of angiosarcoma of pelvis with pulmonary metastases which responded to paclitaxel]. Gan To Kagaku Ryoho; 2007 Dec;34(13):2275-7
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  • [Title] [A case of angiosarcoma of pelvis with pulmonary metastases which responded to paclitaxel].
  • Bone scintigram and MRI revealed multiple osteolytic lesions in pelvis and lumbar spine.
  • Biopsy of the bone lesion established a diagnosis of angiosarcoma.
  • Chemotherapy with paclitaxel and palliative radiotherapy for the bone were initiated.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Bone Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Lung Neoplasms / secondary. Paclitaxel / therapeutic use. Pelvic Bones

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  • (PMID = 18079629.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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23. Nascimento AF, Raut CP, Fletcher CD: Primary angiosarcoma of the breast: clinicopathologic analysis of 49 cases, suggesting that grade is not prognostic. Am J Surg Pathol; 2008 Dec;32(12):1896-904
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the breast: clinicopathologic analysis of 49 cases, suggesting that grade is not prognostic.
  • Mammary angiosarcoma is a rare neoplasm, accounting for about 0.05% of all primary malignancies of the breast.
  • Forty-nine cases of primary angiosarcoma of the breast were retrieved from our files.
  • Ten patients (24.4%) showed evidence of local recurrence within 11 to 60 months (median 36) after diagnosis.
  • Twenty-four patients (58.5%) thus far have developed metastases, which were most commonly to lung, liver, skin, and bone.
  • Time interval between diagnosis and metastasis ranged from 2 to 144 months (median 34).
  • In conclusion, mammary angiosarcoma is a rare disease that affects relatively younger patients.
  • This tumor seems to have an overall similar clinical course as other types of angiosarcoma arising in skin or soft tissue; it carries a moderate risk of local recurrence, and a high risk of metastasis and death.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology

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  • (PMID = 18813119.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Miyake M, Tateishi U, Maeda T, Arai Y, Hasegawa T, Sugimura K: MR features of angiosarcoma in a patient with Maffucci's syndrome. Radiat Med; 2005 Nov;23(7):508-12
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  • [Title] MR features of angiosarcoma in a patient with Maffucci's syndrome.
  • These bone and soft tissue tumors have the potential of malignant transformation to various histologic types: chondrosarcoma, osteosarcoma, fibrosarcoma, and angiosarcoma.
  • We report a rare case of Maffucci's syndrome with soft tissue angiosarcoma of the leg to illustrate MRI findings with pathologic correlations.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Magnetic Resonance Imaging / methods. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 16485543.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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25. Kahraman A, Miller M, Baba H, Gerken G, Hilgard P: [Angiosarcoma of the liver as a rare cause of rapidly progressive liver failure]. Med Klin (Munich); 2006 Sep 15;101(9):746-50
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  • [Title] [Angiosarcoma of the liver as a rare cause of rapidly progressive liver failure].
  • BACKGROUND: Angiosarcoma of the liver is a rare, highly malignant and sometimes diffusely infiltrating vessel tumor with rapid progression and poor prognosis.
  • In addition, MRI was suspicious of bone metastases.
  • Sonographically guided percutaneous liver biopsy established the diagnosis of a malignant vascular tumor with diffuse infiltration of the liver parenchyma.
  • Therefore, the differential diagnosis of a peliosis hepatis was raised.
  • However, histology confirmed the diagnosis of a malignant angiosarcoma with diffuse osseous metastases.
  • CONCLUSION: A diffuse infiltration of the liver by an angiosarcoma in the absence of any definite lesions may lead to a substantial delay of the diagnosis.
  • The only relevant differential diagnosis in this case is the equally rare peliosis hepatis.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Liver Failure / etiology. Liver Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Bone Neoplasms / secondary. Diagnosis, Differential. Disease Progression. Esophageal and Gastric Varices / pathology. Fatal Outcome. Gastrointestinal Hemorrhage / pathology. Humans. Liver / pathology. Liver Cirrhosis, Alcoholic / diagnosis. Liver Cirrhosis, Alcoholic / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Peliosis Hepatis / diagnosis. Peliosis Hepatis / pathology

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  • (PMID = 16977400.001).
  • [ISSN] 0723-5003
  • [Journal-full-title] Medizinische Klinik (Munich, Germany : 1983)
  • [ISO-abbreviation] Med. Klin. (Munich)
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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26. Siddaraju N, Soundararaghavan J, Bundele MM, Roy SK: Fine needle aspiration cytology of epithelioid angiosarcoma: a case report. Acta Cytol; 2008 Jan-Feb;52(1):109-13
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  • [Title] Fine needle aspiration cytology of epithelioid angiosarcoma: a case report.
  • Few studies have described cytomorphologic features of hemangioendothelioma and angiosarcoma on fine needle aspiration cytology (FNAC).
  • We describe epithelioid angiosarcoma, diagnosed on FNAC, in which a differential diagnosis of histiocytosis and inflammatory granulation tissue was considered.
  • The forehead lesion was radiologiocally associated with a lytic lesion in the bone.
  • Epithelioid hemangioendothelioma/angiosarcoma, histiocytosis and inflammatory granulation tissue were considered.
  • A cytologic diagnosis of epithelioid angiosarcoma/epithelioid hemangioendothelioma was suggested and confirmed on histopathologic and immunohistochemical examination.
  • CONCLUSION: Cellular aspirates from malignant epithelioid endothelial tumors involving bone may be cytologically mistaken for histiocytosis and, rarely, inflammatory granulation tissue.
  • However, prominent vascular pattern with striking endothelial cell atypia, presence of mitotic figures and careful search for presence of endothelial differentiation are helpful in accurate cytologic diagnosis.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hemangioendothelioma, Epithelioid / diagnosis. Hemangiosarcoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Granulation Tissue / pathology. Histiocytosis / diagnosis. Humans. Immunohistochemistry. Inflammation / diagnosis. Male

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  • (PMID = 18323286.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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27. Gatcombe HG, Olson TA, Esiashvili N: Metastatic primary angiosarcoma of the breast in a pediatric patient with a complete response to systemic chemotherapy and definitive radiation therapy: case report and review of the literature. J Pediatr Hematol Oncol; 2010 Apr;32(3):192-4
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  • [Title] Metastatic primary angiosarcoma of the breast in a pediatric patient with a complete response to systemic chemotherapy and definitive radiation therapy: case report and review of the literature.
  • We present a case of a rare malignancy, primary breast angiosarcoma, in a 15-year-old girl.
  • She has no evidence of disease recurrence 44 months from her initial diagnosis.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / therapy. Breast Neoplasms / therapy. Hemangiosarcoma / therapy. Mediastinal Neoplasms / therapy. Radiotherapy

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  • (PMID = 20186104.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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28. Dunlap JB, Magenis RE, Davis C, Himoe E, Mansoor A: Cytogenetic analysis of a primary bone angiosarcoma. Cancer Genet Cytogenet; 2009 Oct;194(1):1-3
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  • [Title] Cytogenetic analysis of a primary bone angiosarcoma.
  • Primary bone angiosarcomas are rare and aggressive vascular malignancies with a high mortality rate.
  • To our knowledge, there are no reported cytogenetic abnormalities in primary bone angiosarcomas, although several have been reported in soft tissue angiosarcomas.
  • We report a case of primary bone angiosarcoma, arising in the tibia of a 79-year-old woman, with a unique clonal chromosomal rearrangement: t(1;14)(p21;q24), that has not been reported in either soft tissue or primary bone angiosarcoma.
  • [MeSH-major] Bone Neoplasms / genetics. Hemangiosarcoma / genetics. Translocation, Genetic

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  • (PMID = 19737647.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Kabukçuoğlu F, Kabukçuoğlu Y, Livaoğlu A, Ozağari A, Armağan R, Kuzgun U: [Epithelioid hemangioendothelioma of bone]. Acta Orthop Traumatol Turc; 2006;40(4):324-8
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  • [Title] [Epithelioid hemangioendothelioma of bone].
  • Epithelioid hemangioendothelioma is a low-grade malignant tumor with a histologic appearance and clinical course between that of a hemangioma and angiosarcoma.
  • It is rarely encountered in the bone.
  • A cystic lesion was noted on a plain radiograph of the left foot, destructing the diaphysis of the first metatarsal bone.
  • Magnetic resonance imaging showed a solid intramedullary lesion involving a large part of the bone.
  • Scintigraphic examination showed uptake in the diaphysis of the left tibia and the first metatarsal bone of the left foot.
  • A diagnosis of epithelioid hemangioendothelioma was made and the patient underwent subtotal resection of the metatarsal bone with reconstruction of the fibula, and a wide resection of the tibial lesion.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hemangioendothelioma, Epithelioid / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Fibula / pathology. Fibula / radiography. Fibula / surgery. Humans. Metatarsal Bones / pathology. Metatarsal Bones / radiography. Metatarsal Bones / surgery. Middle Aged. Tibia / pathology. Tibia / radiography. Tibia / surgery. Wounds and Injuries

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  • (PMID = 17063057.001).
  • [ISSN] 1017-995X
  • [Journal-full-title] Acta orthopaedica et traumatologica turcica
  • [ISO-abbreviation] Acta Orthop Traumatol Turc
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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30. Van Dyck P, Vanhoenacker FM, Vogel J, Venstermans C, Kroon HM, Gielen J, Parizel PM, Bloem JL, De Schepper AM: Prevalence, extension and characteristics of fluid-fluid levels in bone and soft tissue tumors. Eur Radiol; 2006 Dec;16(12):2644-51
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  • [Title] Prevalence, extension and characteristics of fluid-fluid levels in bone and soft tissue tumors.
  • The purpose of this study was to determine the prevalence, extension and signal characteristics of fluid-fluid levels in a large series of 700 bone and 700 soft tissue tumors.
  • Out of a multi-institutional database, MRI of 700 consecutive patients with a bone tumor and MRI of 700 consecutive patients with a soft tissue neoplasm were retrospectively reviewed for the presence of fluid-fluid levels.
  • Of 700 patients with a bone tumor, 19 (10 male and 9 female; mean age, 29 years) presented with a fluid-fluid level (prevalence 2.7%).
  • Diagnoses included aneurysmal bone cyst (ten cases), fibrous dysplasia (two cases), osteoblastoma (one case), simple bone cyst (one case), telangiectatic osteosarcoma (one case), "brown tumor" (one case), chondroblastoma (one case) and giant cell tumor (two cases).
  • Diagnoses included cavernous hemangioma (12 cases), synovial sarcoma (3 cases), angiosarcoma (1 case), aneurysmal bone cyst of soft tissue (1 case), myxofibrosarcoma (1 case) and high-grade sarcoma "not otherwise specified" (2 cases).
  • In our series, the largest reported in the literature to the best of our knowledge, the presence of fluid-fluid levels is a rare finding with a prevalence of 2.7 and 2.9% in bone and soft tissue tumors, respectively.
  • Fluid-fluid levels remain a non-specific finding and can occur in a wide range of bone and soft tissue tumors, both benign and malignant.
  • Therefore, they cannot be considered diagnostic of any particular type of tumor, and the diagnosis should be made on the basis of other radiological and clinical findings.
  • [MeSH-major] Body Fluids / metabolism. Bone Neoplasms / pathology. Magnetic Resonance Imaging / methods. Soft Tissue Neoplasms / pathology

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  • (PMID = 16612549.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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31. Kimura T, Mukai M, Kaneko Y, Hirakata M, Okamoto S, Sakamoto M, Okada Y, Ikeda Y: Unusual hemangioendothelioma of the liver with epithelioid morphology associated with marked eosinophilia: autopsy case. Pathol Int; 2006 Nov;56(11):694-701
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  • Biopsy and autopsy revealed an unusual epithelioid vascular tumor in the liver, which is histologically distinct from epithelioid hemangioma, epithelioid hemangioendothelioma, or epithelioid angiosarcoma.
  • The tumor cells had vasoformative and partly solid growth with no severe nuclear atypia and very low mitotic activity, and the histological features were similar to those of the entity recognized as hemangioendothelioma of bone.
  • Organs other than the liver, for example the testes and bone, were also involved.
  • This tumor should be considered in the differential diagnosis of severe eosinophilia.
  • [MeSH-minor] Adult. Diagnosis, Differential. Fatal Outcome. Hepatomegaly / complications. Hepatomegaly / pathology. Humans. Interleukin-5 / blood. Male. Tomography, X-Ray Computed

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  • (PMID = 17040294.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Interleukin-5
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32. Gupta A, Saifuddin A, Briggs TW, Flanagan AM: Subperiosteal hemangioendothelioma of the femur. Skeletal Radiol; 2006 Oct;35(10):793-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Primary neoplastic vascular lesions of bone are rare, and include haemangiomas, haemangioendothelioma, epithelioid haemangioendothelioma and angiosarcoma.
  • These lesions may be multicentric, and when they involve bone are typically intraosseous and lytic.
  • The nomenclature for vascular neoplasms in bone is discussed.
  • [MeSH-major] Femoral Neoplasms / diagnosis. Hemangioendothelioma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • [Cites] Cancer. 1971 Jun;27(6):1403-14 [5088217.001]
  • [Cites] Am J Surg Pathol. 1986 Nov;10 (11):754-64 [2430475.001]
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  • (PMID = 16421750.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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33. Tayeb T, Bouzaiene M: [Epithelioid hemangioendothelioma mimicking an occipital artery aneurysm]. Rev Stomatol Chir Maxillofac; 2007 Nov;108(5):451-4
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  • Its clinical course being close to that of hemangioma and conventional angiosarcoma, the term epithelioid hemangioendothelioma was suggested.
  • Finally it was the histological examination which confirmed the diagnosis of epithelioid hemangioendothelioma.
  • [MeSH-major] Aneurysm / diagnosis. Head and Neck Neoplasms / diagnosis. Hemangioendothelioma, Epithelioid / diagnosis. Scalp / blood supply. Scalp / pathology
  • [MeSH-minor] Adult. Arteries. Diagnosis, Differential. Female. Humans. Occipital Bone

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  • (PMID = 17916371.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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34. Jeong SW, Woo HY, You CR, Huh WH, Bae SH, Choi JY, Yoon SK, Jung CK, Jung ES: [A case of hepatic epithelioid hemangioendothelioma that caused extrahepatic metastases without intrahepatic recurrence after hepatic resection]. Korean J Hepatol; 2008 Dec;14(4):525-31
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  • There is no generally accepted therapeutic strategy because of its rarity and the variable natural course between hemangioma and angiosarcoma.
  • We report a case of a 64-year old woman who underwent hepatic resection due to epithelioid hemangioendothelioma in the right lobe that progressed to extrahepatic metastases of the bone, pleura, and peritoneum 22 months later.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Hemangioendothelioma, Epithelioid / secondary. Liver Neoplasms / diagnosis
  • [MeSH-minor] Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Bone Neoplasms / secondary. Female. Hepatectomy. Humans. Lung Neoplasms / diagnosis. Lung Neoplasms / pathology. Lung Neoplasms / secondary. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 19119248.001).
  • [ISSN] 1738-222X
  • [Journal-full-title] The Korean journal of hepatology
  • [ISO-abbreviation] Korean J Hepatol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
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35. Ducimetière F, Lurkin A, Ranchère-Vince D, Decouvelaere AV, Isaac S, Claret-Tournier C, Suignard Y, Salameire D, Cellier D, Alberti L, Bringuier PP, Blay JY, Ray-Coquard I: [Incidence rate, epidemiology of sarcoma and molecular biology. Preliminary results from EMS study in the Rhône-Alpes region]. Bull Cancer; 2010 Jun;97(6):629-41
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  • [Title] [Incidence rate, epidemiology of sarcoma and molecular biology. Preliminary results from EMS study in the Rhône-Alpes region].
  • They can be grouped into 3 general categories, soft tissue sarcoma, visceral and primary bone sarcoma, which have different staging and treatment approaches.
  • This review includes a discussion of both soft tissue sarcomas (unclassified sarcoma, liposarcoma, leiomyosarcoma, synovial sarcoma, dermatofibrosarcoma protuberans, angiosarcoma, Kaposi sarcoma, gastrointestinal stromal tumor, rhabdomyosarcoma, ...) and primary bone sarcomas (osteosarcoma, Ewing sarcoma and chondrosarcoma).
  • The approach to a patient with a sarcoma begins with a biopsy that obtains adequate tissue for diagnosis without interfering with subsequent optimal definitive surgery.
  • Subsequent treatment depends on the specific type of sarcoma.
  • [MeSH-major] Bone Neoplasms / epidemiology. Sarcoma / epidemiology. Soft Tissue Neoplasms / epidemiology


36. Bölke E, Gripp S, Peiper M, Budach W, Schwarz A, Orth K, Reinecke P, van de Nes JA: Multifocal epithelioid hemangioendothelioma: case report of a clinical chamaeleon. Eur J Med Res; 2006 Nov 30;11(11):462-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Epithelioid hemangioendothelioma is an extremely rare vascular bone tumor with a slow growth and poor prognosis.
  • Various synonyms for epithelioid hemangioendothelioma are used clinically: low grade anaplastic angiosarcoma, cellular hemangioma, histiocytoid hemangioma and angioendothelioma.
  • Tumor histology of the bone and liver biopsies confirmed the diagnosis of epithelioid hemangioendothelioma.
  • [MeSH-minor] Angiogenesis Inhibitors / therapeutic use. Diagnosis, Differential. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Syndrome. Thalidomide / therapeutic use. Tomography, X-Ray Computed

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  • (PMID = 17182357.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 4Z8R6ORS6L / Thalidomide
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37. Kajihara Y, Ikawa F, Ohbayashi N, Imada Y, Hidaka T, Matsushige T, Mitsuhara T, Inagawa T, Ohama E: [Hemangioendothelioma of the brain presenting with intracerebral hemorrhage: a case report]. No To Shinkei; 2005 Aug;57(8):690-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hemangioendothelioma (HE) is an uncommon vascular tumor that is intermediate in histological appearance between a hemangioma and an angiosarcoma.
  • It has been reported in the liver, lung, heart, mediastinum, lymph nodes, extremity, and bone.
  • Intratumoral hemorrhage was indicated and preoperative diagnosis was cavernous angioma.

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  • (PMID = 16146213.001).
  • [ISSN] 0006-8969
  • [Journal-full-title] Nō to shinkei = Brain and nerve
  • [ISO-abbreviation] No To Shinkei
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 19
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38. Skubitz KM, D'Adamo DR: Sarcoma. Mayo Clin Proc; 2007 Nov;82(11):1409-32
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  • [Title] Sarcoma.
  • They can be grouped into 2 general categories, soft tissue sarcoma and primary bone sarcoma, which have different staging and treatment approaches.
  • This review includes a discussion of both soft tissue sarcomas (malignant fibrous histiocytoma, liposarcoma, leiomyosarcoma, synovial sarcoma, dermatofibrosarcoma protuberans, angiosarcoma, Kaposi sarcoma, gastrointestinal stromal tumor, aggressive fibromatosis or desmoid tumor, rhabdomyosarcoma, and primary alveolar soft-part sarcoma) and primary bone sarcomas (osteosarcoma, Ewing sarcoma, giant cell tumor, and chondrosarcoma).
  • The approach to a patient with a sarcoma begins with a biopsy that obtains adequate tissue for diagnosis without interfering with subsequent optimal definitive surgery.
  • Subsequent treatment depends on the specific type of sarcoma.
  • [MeSH-major] Bone Neoplasms / therapy. Sarcoma / therapy. Soft Tissue Neoplasms / therapy

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  • (PMID = 17976362.001).
  • [ISSN] 0025-6196
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 391
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39. Siegel HJ, Dunahm WH, Lopez-Ben R, Siegal GP: Intracranial metastasis from synovial sarcoma. Orthopedics; 2008 Apr;31(4):405
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  • [Title] Intracranial metastasis from synovial sarcoma.
  • It is not unusual for synovial sarcoma to present initially after a traumatic event.
  • Synovial sarcoma rarely metastasizes to the skeleton and when it occurs, it most commonly involves the long bones.
  • Reports of other sarcomas having intracranial metastasis include rhabdomyosarcoma, angiosarcoma, fibrosarcoma, liposarcoma, Ewing's sarcoma, and clear cell sarcoma from the kidney.
  • It is often difficult to distinguish between the synchronous or metachronous appearance of a second primary and soft tissue sarcoma metastasis.
  • Open biopsies confirmed synovial sarcoma in both regions.
  • Staging studies, including computed tomography (CT) of his chest, abdomen/pelvis and bone scan were otherwise negative for metastasis.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / secondary. Muscle Neoplasms / diagnosis. Muscle Neoplasms / therapy. Sarcoma, Synovial / diagnosis. Sarcoma, Synovial / secondary

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  • (PMID = 19292263.001).
  • [ISSN] 0147-7447
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Deyrup AT, Tighiouart M, Montag AG, Weiss SW: Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. Am J Surg Pathol; 2008 Jun;32(6):924-7
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  • Epithelioid hemangioendothelioma (EHE) of soft tissue is a distinctive vascular tumor that has been variously considered a tumor of borderline malignancy and low-grade angiosarcoma.
  • Eleven patients (22%) had metastatic disease affecting lung (6), lymph node (4), liver (2), and bone, retroperitoneum, and soft tissue (1 each).
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 18551749.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. Fleshman R, Mayerson J, Wakely PE Jr: Fine-needle aspiration biopsy of high-grade sarcoma: a report of 107 cases. Cancer; 2007 Dec 25;111(6):491-8
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  • [Title] Fine-needle aspiration biopsy of high-grade sarcoma: a report of 107 cases.
  • BACKGROUND: To the authors' knowledge, few studies exist demonstrating the reliability of fine-needle aspiration (FNA) biopsy for high-grade sarcoma (HGS).
  • RESULTS: A total of 107 FNA samples from 98 patients (age range, 13-90 years, with a male:female ratio of 1:1) had an FNA diagnosis of HGS, or had HGS and a prior FNA diagnosis of another entity.
  • The positive predictive value of an FNA diagnosis of HGS was 97% (88 of 91 cases).
  • Fifty-four cases were diagnosed as HGS, not otherwise specified, 8 as myxofibrosarcoma, 8 as osteosarcoma, 5 as malignant peripheral nerve sheath tumor, 5 as leiomyosarcoma, 4 as Ewing sarcoma, 4 as liposarcoma, 2 as epithelioid sarcoma, and 1 as angiosarcoma.
  • FNA diagnosis was confirmed histologically in 88% of cases, clinically in 7% of cases, and cytogenetically in 1% of cases; 3% of cases had false-positive results and 1 patient was lost to follow-up.
  • Sixteen of 19 patients received neoadjuvant chemotherapy based on the FNA diagnosis alone.
  • CONCLUSIONS: A cytopathologic diagnosis of HGS was found to be accurate in 88 of 97 cases (91%) with follow-up.
  • A FNA biopsy diagnosis of HGS appears to be clinically reliable in a high percentage of cases when used in close conjunction with the orthopedic team.
  • [MeSH-major] Biopsy, Fine-Needle. Cytodiagnosis. Sarcoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antineoplastic Agents / therapeutic use. Bone Neoplasms / diagnosis. Female. Humans. Male. Middle Aged. Neoadjuvant Therapy. Predictive Value of Tests. Reproducibility of Results

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  • (PMID = 17941014.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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42. Santiago Recuerda A, Corpa Rodríguez ME, García-Sánchez Girón J, Díaz-Agero Alvarez P, Vázquez Pelillo J, Casillas Pajuelo M: [Vascular tumors arising in the chest wall: 25 years' experience]. Arch Bronconeumol; 2005 Jan;41(1):53-6

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  • Four of them were soft tissue tumors, and two involved bone.
  • The histologic diagnoses were hemangioendothelioma (1), low-grade angiosarcoma (1), and hemangioma (4).
  • The diagnosis was established after surgery in all cases except one that had been previously diagnosed during an attempted resection before the patient came to our hospital.

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  • (PMID = 15676137.001).
  • [ISSN] 0300-2896
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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43. Noack F, Balleisen L, Valent P, Horny HP: Angiosarcoma of bone marrow with unusual expression of chymase: diagnosis in a trephine biopsy specimen. J Clin Pathol; 2007 Oct;60(10):1183

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  • [Title] Angiosarcoma of bone marrow with unusual expression of chymase: diagnosis in a trephine biopsy specimen.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Bone Marrow Neoplasms / pathology. Chymases / metabolism. Hemangiosarcoma / pathology

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  • [Cites] Circulation. 2001 Sep 11;104(11):1274-9 [11551879.001]
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  • (PMID = 17906075.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.21.39 / Chymases
  • [Other-IDs] NLM/ PMC2014849
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