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Items 1 to 100 of about 1138
1. Mehta RS, Mikhail M: Post-irradiation cutaneous angiosarcoma. Cases J; 2008;1(1):241

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Post-irradiation cutaneous angiosarcoma.
  • Angiosarcoma is a rare and highly malignant tumor with potential to recur despite treatment, and carries a poor prognosis.
  • We present a case of cutaneous angiosarcoma which occurred at lumpectomy site in a patient with a history of breast cancer and radiation to the breast.
  • The tumor kept on recurring repetitively despite continual treatments, and the patient finally succumbed to the disease roughly four years after initial diagnosis.

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  • [Cites] Ann Surg Oncol. 2007 Jun;14(6):1953-67 [17356953.001]
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  • (PMID = 18925942.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2605761
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2. Kar A, Mukhopadhyay D, Das SS, Swain NN, Das BM, Nayak M, Rath J, Satpathy S: Cytodiagnosis of angiosarcoma of breast. Indian J Pathol Microbiol; 2008 Jul-Sep;51(3):427-9
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  • [Title] Cytodiagnosis of angiosarcoma of breast.
  • The case was diagnosed by preoperative cytology as angiosarcoma of breast, after which, she underwent modified radical mastectomy.
  • Angiosarcoma of breast is uncommon with extremely bad prognosis.
  • [MeSH-major] Breast Neoplasms / diagnosis. Hemangiosarcoma / diagnosis

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  • (PMID = 18723981.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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3. Armah HB, Rao UN, Parwani AV: Primary angiosarcoma of the testis: report of a rare entity and review of the literature. Diagn Pathol; 2007;2:23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the testis: report of a rare entity and review of the literature.
  • BACKGROUND: Primary testicular angiosarcomas are extremely rare, and their clinicopathologic features are not well described.
  • Our objective was to further define the clinical features and pathologic spectra of primary testicular angiosarcomas.
  • After excluding 2 cases because they did not involve the testis, we identified 4 previously reported cases of true primary testicular angiosarcoma.
  • We also searched the electronic medical archival records of our institution and identified one additional unreported case of true primary testicular angiosarcomas.
  • Data were extracted on the demographics, predisposing factors, clinical presentation, gross pathology, microscopic pathology, immunophenotype, therapy, and outcomes of each of these 5 cases of true primary testicular angiosarcomas.
  • RESULTS: Primary testicular angiosarcomas were found at a mean age of 43.4 years.
  • One patient had multiple metastatic recurrences but eventual outcome was not available, and 1 patient died a month after diagnosis from stroke but no autopsy was performed.
  • CONCLUSION: Primary testicular angiosarcomas are typically rare tumors of men of all ages that appear to segregate into 2 groups; one associated with teratoma and occurring in young people, and the other occurring in the elderly and not associated with germ cell neoplasm, but may be associated with chronic hydrocele.
  • They present with advanced disease and show a wide histologic spectrum.

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  • (PMID = 17601346.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1919353
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4. Puizina-Ivić N, Bezić J, Marasović D, Gotovac V, Carija A, Bozić M: Angiosarcoma arising in sclerodermatous skin. Acta Dermatovenerol Alp Pannonica Adriat; 2005 Mar;14(1):20-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma arising in sclerodermatous skin.
  • We report a case of cutaneous angiosarcoma in a 77-year-old female patient with systemic sclerosis.
  • The pathohistological diagnosis was moderately differentiated angiosarcoma.
  • This is the first report of cutaneous angiosarcoma occurring in sclerodermatous skin.
  • [MeSH-major] Facial Neoplasms / etiology. Hemangiosarcoma / etiology. Scleroderma, Systemic / complications. Scleroderma, Systemic / physiopathology. Skin Neoplasms / etiology

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  • (PMID = 15818442.001).
  • [ISSN] 1318-4458
  • [Journal-full-title] Acta dermatovenerologica Alpina, Pannonica, et Adriatica
  • [ISO-abbreviation] Acta Dermatovenerol Alp Pannonica Adriat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Slovenia
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5. Köhler HF, Neves RI, Brechtbühl ER, Mattos Granja NV, Ikeda MK, Kowalski LP: Cutaneous angiosarcoma of the head and neck: report of 23 cases from a single institution. Otolaryngol Head Neck Surg; 2008 Oct;139(4):519-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous angiosarcoma of the head and neck: report of 23 cases from a single institution.
  • BACKGROUND: To report a single-institution experience in the treatment of cutaneous head and neck angiosarcoma.
  • [MeSH-major] Head and Neck Neoplasms / mortality. Hemangiosarcoma / mortality. Skin Neoplasms / mortality

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  • (PMID = 18922337.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Gennaro M, Valeri B, Casalini P, Carcangiu ML, Gronchi A, Conti AR, Agresti R, Greco M: Angiosarcoma of the breast and vascular endothelial growth factor receptor. Tumori; 2010 Nov-Dec;96(6):930-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the breast and vascular endothelial growth factor receptor.
  • BACKGROUND: Breast angiosarcoma is rare and often associated with previous breast cancer treatment.
  • The expression of vascular endothelial growth factor receptor was also evaluated, as it may be a potential target for anti-angiogenic therapy.
  • PATIENTS AND METHODS: We retrospectively assessed outcomes in relation to age, association with previous breast-conserving treatment for breast cancer, tumor size, and grade in 19 patients without metastases at diagnosis.
  • Vascular endothelial growth factor receptor was also assessed.
  • There were 6 local recurrences and 6 deaths for disease progression.
  • Five-year disease-free survival and overall survival were 53% (95% CI, 20-86%) and 49% (95% CI, 14-84%), respectively.
  • Vascular endothelial growth factor receptor was positive in 50% of cases and was more frequent in better differentiated cancer.
  • CONCLUSIONS: The association of vascular endothelial growth factor receptor with G1/G2 tumors requires further investigations.
  • Our findings suggest that anti-angiogenic treatment in vascular endothelial growth factor receptor-positive cases be considered as a novel therapeutic modality in this rare and aggressive disease.
  • [MeSH-major] Angiogenesis Inhibitors / therapeutic use. Breast Neoplasms / metabolism. Neoplasms, Second Primary / metabolism. Receptors, Vascular Endothelial Growth Factor / drug effects. Receptors, Vascular Endothelial Growth Factor / metabolism
  • [MeSH-minor] Disease-Free Survival. Female. Gene Expression Regulation, Neoplastic. Hemangiosarcoma / drug therapy. Hemangiosarcoma / etiology. Hemangiosarcoma / metabolism. Hemangiosarcoma / pathology. Hemangiosarcoma / therapy. Humans. Male. Mastectomy, Segmental. Middle Aged. Radiotherapy, Adjuvant / adverse effects. Retrospective Studies. Treatment Outcome

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  • (PMID = 21388054.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; EC 2.7.10.1 / Receptors, Vascular Endothelial Growth Factor; Angiosarcoma of the breast
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7. Tada Y, Takiguchi Y, Terada J, Yoshida T, Shinozaki A, Sakao S, Kasahara Y, Kurosu K, Tanabe N, Tatsumi K, Hiroshima K, Kuriyama T: [A case of angiosarcoma of pelvis with pulmonary metastases which responded to paclitaxel]. Gan To Kagaku Ryoho; 2007 Dec;34(13):2275-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of angiosarcoma of pelvis with pulmonary metastases which responded to paclitaxel].
  • Biopsy of the bone lesion established a diagnosis of angiosarcoma.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Bone Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Lung Neoplasms / secondary. Paclitaxel / therapeutic use. Pelvic Bones

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  • (PMID = 18079629.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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8. Nagano T, Yamada Y, Ikeda T, Kanki H, Kamo T, Nishigori C: Docetaxel: a therapeutic option in the treatment of cutaneous angiosarcoma: report of 9 patients. Cancer; 2007 Aug 1;110(3):648-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Docetaxel: a therapeutic option in the treatment of cutaneous angiosarcoma: report of 9 patients.
  • BACKGROUND: Effective treatment options are limited for patients with cutaneous angiosarcoma (AS).
  • Another taxane drug, paclitaxel, reportedly had unique activity in the treatment of AS of the scalp and neck and acquired immunodeficiency syndrome-related Kaposi sarcoma.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Hemangiosarcoma / drug therapy. Skin Neoplasms / drug therapy. Taxoids / therapeutic use

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  • [Copyright] (c) 2007 American Cancer Society.
  • (PMID = 17582627.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Taxoids; 15H5577CQD / docetaxel
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9. Infante PF, Petty SE, Groth DH, Markowitz G, Rosner D: Vinyl chloride propellant in hair spray and angiosarcoma of the liver among hairdressers and barbers: case reports. Int J Occup Environ Health; 2009 Jan-Mar;15(1):36-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vinyl chloride propellant in hair spray and angiosarcoma of the liver among hairdressers and barbers: case reports.
  • Two cases of angiosarcoma of the liver (ASL) are, to the best of our knowledge, the first literature reports of such cases identified among hairdressers and barbers who used hair sprays containing vinyl chloride (VC) as a propellant.
  • [MeSH-major] Aerosol Propellants / poisoning. Beauty Culture. Cosmetics / poisoning. Hemangiosarcoma / chemically induced. Liver Neoplasms / chemically induced. Occupational Diseases / chemically induced. Vinyl Chloride / poisoning

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  • (PMID = 19267125.001).
  • [ISSN] 1077-3525
  • [Journal-full-title] International journal of occupational and environmental health
  • [ISO-abbreviation] Int J Occup Environ Health
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aerosol Propellants; 0 / Cosmetics; WD06X94M2D / Vinyl Chloride
  • [Number-of-references] 59
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10. Verdolini R, Goteri G, Criante P, Giangiacomi M, Cerio R: Recurrent epithelioid angiosarcoma of the scalp simulating melanoma. A 10-year follow-up. J Eur Acad Dermatol Venereol; 2005 Nov;19(6):732-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent epithelioid angiosarcoma of the scalp simulating melanoma. A 10-year follow-up.
  • We present a case of an intriguing mesenchymal neoplasm of the scalp that recurred several times over 10 years before a final diagnosis was possible.
  • The case was sent for expert opinions to various international dermatopathological authorities and was, for a long time, unanimously interpreted as malignant melanoma.
  • This diagnosis was supported by immunohistochemical examinations demonstrating S-100 positivity.
  • Nevertheless, the clinical behaviour, as well as some histopathological features raised doubt regarding the diagnosis.
  • Only after the last recurrence, followed by a repeat extensive immunohistochemical study, the diagnosis of epithelioid angiosarcoma was made.
  • Histologically malignant melanoma can be highly misleading and in literature, reports of misinterpreted cases of melanoma are published.
  • In contrast, tumours that can simulate melanoma are also not infrequent and it is essential to perform immunohistochemistry to confirm diagnosis and exclude a melanocytic lesion.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Scalp / pathology. Skin Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Melanoma / diagnosis. Middle Aged

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  • (PMID = 16268881.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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11. Pandit SA, Fiedler PN, Westcott JL: Primary angiosarcoma of the lung. Ann Diagn Pathol; 2005 Oct;9(5):302-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the lung.
  • Primary angiosarcoma of the lung is a rare disorder with few cases reported in the literature [Patel AM, Ryu JH.
  • Angiosarcoma in the lung.
  • We present a case of primary angiosarcoma of the lung in a 79-year-old woman.
  • Lung biopsy revealed a multifocal malignant neoplasm with areas of hemorrhage.
  • The histologic, cytologic, and immunophenotypic features were characteristic of epithelioid angiosarcoma.
  • This case report contributes to the sparse literature on this disease and provides computed tomographic and pathologic correlation in a patient with hemorrhagic pulmonary nodules.
  • [MeSH-major] Hemangiosarcoma / pathology. Lung Neoplasms / pathology
  • [MeSH-minor] Aged. Aspergillosis / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Immunophenotyping. Tomography, X-Ray Computed. Vasculitis / pathology

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  • (PMID = 16198962.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ: Angiosarcoma. Lancet Oncol; 2010 Oct;11(10):983-91
SciCrunch. KEGG: Data: Disease Annotation .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma.
  • Angiosarcomas are rare soft-tissue sarcomas of endothelial cell origin that have a poor prognosis.
  • They can arise anywhere in the body, most commonly presenting as cutaneous disease in elderly white men, involving the head and neck and particularly the scalp.
  • They can be caused by therapeutic radiation or chronic lymphoedema and hence secondary breast angiosarcomas are an important subgroup.
  • Recent work has sought to establish the molecular biology of angiosarcomas and identify specific targets for treatment.
  • Interest is now focused on trials of vascular-targeted drugs, which are showing promise in the control of angiosarcomas.
  • In this review we discuss angiosarcoma and its current management, with a focus on clinical trials investigating the treatment of advanced disease.
  • [MeSH-major] Hemangiosarcoma / therapy
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Male. Neoplasm Staging. Predictive Value of Tests. Risk Factors. Treatment Outcome

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20537949.001).
  • [ISSN] 1474-5488
  • [Journal-full-title] The Lancet. Oncology
  • [ISO-abbreviation] Lancet Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
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13. Fury MG, Antonescu CR, Van Zee KJ, Brennan MF, Maki RG: A 14-year retrospective review of angiosarcoma: clinical characteristics, prognostic factors, and treatment outcomes with surgery and chemotherapy. Cancer J; 2005 May-Jun;11(3):241-7
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  • [Title] A 14-year retrospective review of angiosarcoma: clinical characteristics, prognostic factors, and treatment outcomes with surgery and chemotherapy.
  • PURPOSE: Angiosarcoma is a rare vascular malignancy, and there are few published data to guide chemotherapy treatment decisions.
  • We present a retrospective analysis of angiosarcoma encompassing all anatomic sites of disease presenting to a single institution over a 14-year period.
  • For patients with unresectable disease, progression-free survival with various chemotherapy regimens is described.
  • One hundred twenty-five patients with angiosarcoma were seen and treated between January 1, 1990 and December 31, 2003.
  • RESULTS: Angiosarcoma showed marked variation by anatomic site regarding gender ratio, median age at diagnosis, overall survival, and response to chemotherapy.
  • Overall 5-year survival was 31% for angiosarcoma.
  • For unresectable angiosarcoma, doxorubicin based regimens yielded progression-free survival of 3.7-5.4 months.
  • Paclitaxel achieved a progression-free survival of 6.8 months for scalp angiosarcoma and 2.8 months for sites below the clavicle.
  • DISCUSSION: Angiosarcoma is an aggressive malignancy characterized by biologic heterogeneity at different anatomic sites and relative sensitivity to paclitaxel and doxorubicin.
  • [MeSH-major] Antibiotics, Antineoplastic / therapeutic use. Antineoplastic Agents, Phytogenic / therapeutic use. Doxorubicin / therapeutic use. Hemangiosarcoma. Neoplasm Staging. Paclitaxel / therapeutic use
  • [MeSH-minor] Adult. Age of Onset. Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Disease Progression. Disease-Free Survival. Female. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Sex Factors

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  • [ErratumIn] Cancer J. 2005 Jul-Aug;11(4):354
  • (PMID = 16053668.001).
  • [ISSN] 1528-9117
  • [Journal-full-title] Cancer journal (Sudbury, Mass.)
  • [ISO-abbreviation] Cancer J
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P01 CA47179
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Antineoplastic Agents, Phytogenic; 80168379AG / Doxorubicin; P88XT4IS4D / Paclitaxel
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14. Fonseca V, Reis G, Lourenço C, Alves C, Vasconcelos AP, Martelo F, Bravio I, Lousinha A, Timóteo AT, Pinto E, Granadeiro J, Pinto Saraiva A: [Pulmonary metastasis in a cardiac angiosarcoma - case report and discussion]. Rev Port Pneumol; 2009 Nov-Dec;15(6):1175-84
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  • [Title] [Pulmonary metastasis in a cardiac angiosarcoma - case report and discussion].
  • [Transliterated title] Metastização pulmonar na apresentação de angiossarcoma cardíaco - Caso clínico e discussão.
  • Admitted to the pulmonology unit patient underwent videothoracsopy which diagnosed cardiac angiosarcoma with pulmonary metastisation.
  • [MeSH-major] Heart Neoplasms / pathology. Hemangiosarcoma / secondary. Lung Neoplasms / secondary

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  • (PMID = 19859633.001).
  • [ISSN] 2172-6825
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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15. Dainese E, Pozzi B, Milani M, Rossi G, Pezzotta MG, Vertemati G, Tricomi P, Sessa F: Primary pleural epithelioid angiosarcoma. A case report and review of the literature. Pathol Res Pract; 2010 Jun 15;206(6):415-9
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  • [Title] Primary pleural epithelioid angiosarcoma. A case report and review of the literature.
  • Malignant vascular tumors are uncommon sarcomas that arise from endothelial cells of small blood vessels and may affect every organ.
  • Even if etiological factors implicated in the development of vascular sarcomas are still unclear, the strongest association with the disease was a history of chronic tuberculous pyothorax, observed only in Japanese patients, while prior radiotherapy and occupational exposure to asbestos have been reported in few Western cases.
  • The mean age at diagnosis was 58 years, and the male to female ratio was 6:1.
  • The overall prognosis was poor, and most of the patients died of disease soon after diagnosis.
  • Histological features and clinical presentation often cause several problems in the differential diagnosis, particularly with mesothelioma and metastasis from poorly differentiated carcinomas.
  • Immunohistochemistry plays an important role in identifying these rare entities, confirming the endothelial origin of the neoplasm with the expression of at least one of the vascular markers CD31, CD34, or factor VIII-related antigen.
  • The overall pathological and immunohistochemical features of the pleural specimens supported the diagnosis of epithelioid angiosarcoma.
  • [MeSH-major] Hemangiosarcoma / pathology. Lung Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diabetes Mellitus, Type 2. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Mesothelioma / pathology. Middle Aged. Neoplasm Metastasis / pathology. Radiculopathy / complications

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  • [Copyright] 2009 Elsevier GmbH. All rights reserved.
  • (PMID = 20089367.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 53
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16. Nicolas MM, Nayar R, Yeldandi A, De Frias DV: Pulmonary metastasis of a postradiation breast epithelioid angiosarcoma mimicking adenocarcinoma. A case report. Acta Cytol; 2006 Nov-Dec;50(6):672-6
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  • [Title] Pulmonary metastasis of a postradiation breast epithelioid angiosarcoma mimicking adenocarcinoma. A case report.
  • BACKGROUND: Epithelioid angiosarcoma (EAS) is a mesenchymal neoplasm that may appear indistinguishable from carcinoma, melanoma and other tumors with epithelioid/epithelial differentiation.
  • Review of the recurrent breast tumor (initially reported as DCIS) and a prior wedge resection of the lung nodules (reported as EAS) showed an epithelial-appearing tumor exhibiting an endothelial immunophenotype CONCLUSION: The cytologic features of EAS may resemble those of other neoplasms.
  • [MeSH-major] Adenocarcinoma / pathology. Breast Neoplasms / pathology. Carcinoma, Intraductal, Noninfiltrating / radiotherapy. Hemangiosarcoma / secondary. Lung Neoplasms / secondary. Neoplasms, Radiation-Induced / pathology. Radiotherapy / adverse effects
  • [MeSH-minor] Biopsy, Fine-Needle / methods. Diagnosis, Differential. Epithelioid Cells / pathology. Female. Humans. Middle Aged

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  • (PMID = 17152281.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Tsolakis I, Lampropoulos G, Zolota V, Papadoulas S, Christeas N: Aortic angiosarcoma with cutaneous metastases. Vascular; 2009 May-Jun;17(3):176-80
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  • [Title] Aortic angiosarcoma with cutaneous metastases.
  • Primary aortic tumors are rare and include a variety of histologic types, including aortic angiosarcomas, with less than 100 cases being reported since the first description of these tumors in 1873.
  • The diagnosis of aortic angiosarcoma is usually confirmed by postoperative histopathologic examination or postmortem study.
  • We present a case of primary aortic angiosarcoma presenting with intermittent claudication and radiologic findings of aortoiliac atherosclerotic disease treated initially with stenting; lower extremity embolic skin metastases developed during follow-up that prompted resection of the aortic bifurcation and restoration of the arterial continuity with a bypass.
  • [MeSH-major] Aortic Diseases / diagnostic imaging. Foot Diseases / etiology. Hemangiosarcoma / diagnostic imaging. Skin Neoplasms / secondary

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  • (PMID = 19476753.001).
  • [ISSN] 1708-5381
  • [Journal-full-title] Vascular
  • [ISO-abbreviation] Vascular
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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18. Chiu O, Frank JD, Dow CA: Hepatic angiosarcoma: detection with computed tomography. Australas Radiol; 2005 Apr;49(2):163-5
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  • [Title] Hepatic angiosarcoma: detection with computed tomography.
  • Hepatic angiosarcoma is a rare vascular neoplasm which occurs typically in men aged between 50 and 70 years.
  • A case of advanced multifocal hepatic angiosarcoma with splenic metastasis is presented with brief discussion of the clinical and histological features.
  • [MeSH-major] Hemangiosarcoma / radiography. Liver Neoplasms / radiography
  • [MeSH-minor] Aged. Diagnosis, Differential. Fatal Outcome. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 15845058.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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19. Danz B, Hellmann A, Stadie V, Dunst J, Richter C, Marsch WCh, Helmbold P: Radiotherapy in multilocalized lymphedema-associated angiosarcoma. Eur J Dermatol; 2005 Nov-Dec;15(6):474-7
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  • [Title] Radiotherapy in multilocalized lymphedema-associated angiosarcoma.
  • We report an 80-year-old woman, suffering from a recurrence of a multilocalized lymphedema-associated angiosarcoma of the right arm.
  • In the tumor periphery, pathological endothelial cell proliferates on pre-existing dilated lymphatic capillaries were detectable, which, together with immunohistology (CD 31+/Desmoplakin-1-2.17+/CD 34-), supported the diagnosis of lymphangiosarcoma.
  • Further studies should elucidate the suitability of radio monotherapy as first-line therapy in lymphedema-associated angiosarcoma with lymphatic endothelium-like immunohistology.
  • [MeSH-major] Hemangiosarcoma / complications. Hemangiosarcoma / radiotherapy. Lymphedema / complications. Skin Neoplasms / complications. Skin Neoplasms / radiotherapy

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  • (PMID = 16280302.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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20. Marthya A, Patinharayil G, Puthezeth K, Sreedharan S, Kumar A, Kumaran CM: Multicentric epithelioid angiosarcoma of the spine: a case report of a rare bone tumor. Spine J; 2007 Nov-Dec;7(6):716-9
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  • [Title] Multicentric epithelioid angiosarcoma of the spine: a case report of a rare bone tumor.
  • BACKGROUND CONTEXT: Epithelioid angiosarcoma (EA) is a high-grade sarcoma of vascular origin.
  • EA is a rare variant of angiosarcoma.
  • The tumor was composed of nests and cords of malignant cells with epithelioid morphology with areas of vascular differentiation, necrosis, and hemorrhage.
  • Anastomosing vascular spaces lined by epithelioid endothelial cells suggested focal endotheliod differentiation.
  • The authors point out the need for immunohistochemical evaluation after careful histological analysis for vascular differentiation for an accurate diagnosis of vascular bone tumors with epithelioid features so that an erroneous diagnosis of metastatic carcinoma can be avoided.
  • EA is marked by the presence of large polygonal epithelioid malignant cells with marked cellular atypia and pleomorphism.
  • Even in the absence of obvious vascular differentiation, abundant intratumoral hemorrhage and intratumoral neutrophils are definite morphologic changes that should suggest a vascular origin.
  • Careful histologic and immunohistochemical analysis will clinch the diagnosis.
  • Even though rare, we stress the importance to be aware of the existence of this tumor, which is essential for correct diagnosis.
  • [MeSH-major] Bone Neoplasms / pathology. Epithelioid Cells / pathology. Hemangiosarcoma / pathology. Magnetic Resonance Imaging. Thoracic Vertebrae / pathology

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  • (PMID = 17998131.001).
  • [ISSN] 1529-9430
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Vogt T: [Angiosarcoma]. Hautarzt; 2008 Mar;59(3):237-48; quiz 249-50
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  • [Title] [Angiosarcoma].
  • [Transliterated title] Angiosarkom.
  • Angiosarcomas are rare tumors accounting for 1-2% of all soft tissue sarcomas.
  • Angiosarcoma favors superficial soft tissues and skin (60%) with a clear predilection for the head and neck region.
  • The average age of the patients presenting with cutaneous angiosarcomas is around 70 years with a peak incidence in the 8th decade.
  • Secondary angiosarcoma after tissue-conserving radiation therapy for carcinoma of the breast represents an increasing problem, both the differentiation between atypical vascular lesions and true aggressive angiosarcoma and the therapy are challenging.
  • The prognosis for angiosarcoma patients is gloomy despite all therapeutic efforts.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Hemangiosarcoma / therapy. Skin Neoplasms / diagnosis. Skin Neoplasms / therapy

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  • (PMID = 18273583.001).
  • [ISSN] 1432-1173
  • [Journal-full-title] Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
  • [ISO-abbreviation] Hautarzt
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 27
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22. Fujii Y, Koibuchi-Yamaoka H, Taniguchi N, Yasuda Y, Nagai H: Metastasis from a primary angiosarcoma of the scalp to the colon: sonographic and CT findings. J Clin Ultrasound; 2008 Feb;36(2):110-2
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  • [Title] Metastasis from a primary angiosarcoma of the scalp to the colon: sonographic and CT findings.
  • We report a case of metastasis to the colon from a primary angiosarcoma of the scalp in a 61-year-old Japanese man and describe the sonographic features and CT findings, with a brief discussion of the clinical and histopathologic findings.
  • Although this entity is extremely rare, it should be considered when a patient with prior diagnosis of angiosarcoma in another organ has focal thickening with preserved compressibility of the wall of the colon.
  • [MeSH-major] Colonic Neoplasms / secondary. Head and Neck Neoplasms / pathology. Hemangiosarcoma / secondary. Scalp. Skin Neoplasms / pathology. Tomography, X-Ray Computed / methods. Ultrasonography, Doppler / methods
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged

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  • [Copyright] (c) 2007 Wiley Periodicals, Inc.
  • (PMID = 17636504.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Indelicato DJ, Keole SR, Shahlaee AH, Morris CG, Gibbs CP, Scarborough MT, Islam S, Marcus RB: Ewing tumors of the chest wall: Local control and long-term outcomes. J Clin Oncol; 2009 May 20;27(15_suppl):e21501

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e21501 Background: Primary sarcomas of the lungs and mediastinum are rare and few data are reported on treatment and results of therapy.
  • Pts characteristics: median age 41 (19-80 y), male/female 19/12; symptoms at diagnosis: dyspnoea (42%), chest and shoulder pain (39%), cough (35%), hemophtoae (13%), discomfort (10%).
  • 5 mediastinal tumours were located as follows: 2 in anterior part, 1 in posterior and 2 in the middle (sarcomas of the heart).
  • 26 lung sarcomas presented as a singular mass in 23 cases and as a metastatic disease in 3.
  • RESULTS: In 20/31 cases the tumour was immediately resected (3 mediastinal masses and 17 lung sarcomas).
  • The histology were: peripheral nerve tumour 7, leiomyosarcoma 4, MFH 2, fibrosarcoma 2, liposarcoma 1, angiosarcoma 2, undifferentiated sarcoma 1, solitary fibrous tumour 2, rhabdomyosarcoma 2, synovialsarcoma 2, pulmonary artery sarcoma 1, pleuropolmonary blastoma 1, malignant hemangiopericytoma 1, mixoid chondrosarcoma 1, ectopic osteosarcoma 1, aggressive fibromatosis 1.
  • Only 4 pts received neoadjuvant chemotherapy, 11 adjuvant CT, 5 exclusive CT + RT for inoperable disease.
  • Of these only 8 are alive (2 with disease).
  • Volume of disease, complete resection and grading are the dominant prognostic factors.
  • CONCLUSIONS: Primary sarcomas of the lungs and mediastinum have a very severe prognosis.

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  • (PMID = 27963390.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Markidou S, Karydas I, Papadopoulos S, Christodoulidou I, Skarpidi E, Maounis N: Fine needle aspiration cytology in primary breast angiosarcoma: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):764-70
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  • [Title] Fine needle aspiration cytology in primary breast angiosarcoma: a case report.
  • BACKGROUND: Angiosarcoma of the breast is an uncommon, aggressive, vascular tumor.
  • The cytomorphologic features of angiosarcomas have rarely been reported.
  • CASE: The present study describes a case of breast angiosarcoma initially diagnosed by fine needle aspiration cytology.
  • Angiosarcoma appeared in the left breast of a 58-year-old woman after 12 years of a mastectomy (without radiotherapy) of the contralateral breast for invasive ductal carcinoma.
  • Both cell types exhibited immunoreactivity for endothelial markers.
  • The diagnosis of angiosarcoma was confirmed by histopathology of the surgically excised tumor.
  • CONCLUSION: Angiosarcoma rarely occurs in the breast, and a definitive diagnosis is extremely difficult relying exclusively on cytologic features.
  • Predominance of epithelioid cells may suggest an epithelial tumor, especially in patients with a history of breast carcinoma, whereas predominance of spindle cells can be misinterpreted as phyllodes tumor or another type of sarcoma.
  • Cell block immunocytochemistry and tumor cell labeling with endothelial markers are necessary for accurate diagnosis.
  • [MeSH-major] Breast / pathology. Breast Neoplasms / pathology. Hemangiosarcoma / pathology
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Epithelial Cells / pathology. Female. Humans. Immunohistochemistry. Mastectomy. Middle Aged

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  • (PMID = 21053536.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Terada T: Fatal poorly differentiated angiosarcoma of the scalp. Int J Clin Exp Pathol; 2010;3(5):541-4
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  • [Title] Fatal poorly differentiated angiosarcoma of the scalp.
  • Cutaneous angiosarcoma is a very rare but aggressive tumor.
  • Angiosarcoma of the scalp is very rare, and a review of the world literature revealed less than 60 cases.
  • Here, the author reports a case of poorly differentiated angiosarcoma of the scalp.
  • The pathological diagnosis was very difficult.
  • The biopsy showed proliferation of malignant spindle cells in the dermis.
  • Intracytoplasmic vacuoles were recognized in the malignant tumor cells in some places.
  • Immunohistochemically, the malignant spindle cells were positive for factor VIII-related antigen (F-VIII-RA), Ulex lectin, CD31, CD34, vimentin, p53 protein.
  • The intracytoplasmic vacuoles were strongly positive for F-VIII-RA, Ulex lectin, CD31, and CD34, The abortive vasoformative channels were moderately positive for these endothelial markers.
  • A pathologic diagnosis of angiosarcoma of the scalp was made.
  • [MeSH-major] Hemangiosarcoma / pathology. Scalp / pathology. Skin Neoplasms / pathology

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  • (PMID = 20606736.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2897108
  • [Keywords] NOTNLM ; CD31 / CD34 / Cutaneous angiosarcoma / Ulex lectin / for factor VIII-related antigen (F-VIII-RA) / p53 protein / scalp / vimentin
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26. Le Corre Y, Avenel-Audran M, Croué A, Steff M, Verret JL: [Cutaneous angiosarcoma of the leg without lymphoedema]. Ann Dermatol Venereol; 2008 Jun-Jul;135(6-7):488-91
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  • [Title] [Cutaneous angiosarcoma of the leg without lymphoedema].
  • [Transliterated title] Angiosarcome cutané de jambe sans lymphoedème associé.
  • BACKGROUND: Cutaneous angiosarcoma is a rare aggressive vascular neoplasm with a poor prognosis, seen chiefly in elderly subjects and usually on the scalp or face.
  • Histological examination showed vascular channels lined with atypical cells consistent with a diagnosis of angiosarcoma.
  • DISCUSSION: The leg is a rare site of cutaneous angiosarcoma.
  • [MeSH-major] Hemangiosarcoma. Leg. Skin Neoplasms

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  • (PMID = 18598799.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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27. Bhati CS, Bhatt AN, Starkey G, Hubscher SG, Bramhall SR: Acute liver failure due to primary angiosarcoma: a case report and review of literature. World J Surg Oncol; 2008 Sep 30;6:104
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  • [Title] Acute liver failure due to primary angiosarcoma: a case report and review of literature.
  • BACKGROUND: Hepatic angiosarcoma is a primary sarcoma of the liver, accounting for only 2% of all primary hepatic malignancies.
  • On further investigation he was found to have primary angiosarcoma of liver.
  • CONCLUSION: The treatment outcomes for hepatic angiosarcoma are poor, we discuss the options available and the need for prompt investigation and establishment of a diagnosis.
  • [MeSH-major] Hemangiosarcoma / complications. Liver Failure, Acute / etiology. Liver Neoplasms / complications

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  • (PMID = 18826593.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0701304
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 28
  • [Other-IDs] NLM/ PMC2567320
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28. Vakkalanka B, Milhem M: Paclitaxel as neoadjuvant therapy for high grade angiosarcoma of the spleen: a brief report and literature review. Clin Med Insights Oncol; 2010 Oct 12;4:107-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Paclitaxel as neoadjuvant therapy for high grade angiosarcoma of the spleen: a brief report and literature review.
  • INTRODUCTION: Splenic angiosarcoma is a rare tumor with only a few cases reported in the literature.
  • We report a case of a locally advanced angiosarcoma rendered operable by treatment with Paclitaxel monotherapy.
  • CASE PRESENTATION: A 69 year old female presented with a high grade splenic angiosarcoma, considered inoperable due to the extent of local spread.
  • CONCLUSION: Chemotherapy options for splenic angiosarcoma are not well studied.

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  • (PMID = 20981134.001).
  • [ISSN] 1179-5549
  • [Journal-full-title] Clinical Medicine Insights. Oncology
  • [ISO-abbreviation] Clin Med Insights Oncol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2956477
  • [Keywords] NOTNLM ; angiosarcoma / paclitaxel / sarcoma / spleen
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29. Delacruz V, Jorda M, Gomez-Fernandez C, Benedetto P, Ganjei P: Fine-needle aspiration diagnosis of angiosarcoma of the spleen: a case report and review of the literature. Arch Pathol Lab Med; 2005 Aug;129(8):1054-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration diagnosis of angiosarcoma of the spleen: a case report and review of the literature.
  • Primary angiosarcoma of the spleen is a very rare neoplasm with a poor prognosis.
  • The definitive diagnosis is usually based on the histologic evaluation of the splenectomy specimen.
  • We describe a case of angiosarcoma diagnosed by fine-needle aspiration cytology prior to splenectomy.
  • A malignant endothelial neoplasm was diagnosed by fine-needle aspiration cytology using immunocytochemistry, and a splenectomy confirmed the presence of angiosarcoma.
  • To our knowledge, this is the first well-documented and confirmed case of primary angiosarcoma of the spleen diagnosed by fine-needle aspiration cytology.
  • [MeSH-major] Biopsy, Fine-Needle. Hemangiosarcoma / secondary. Splenic Neoplasms / pathology

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  • (PMID = 16048401.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Biomarkers, Tumor; 9001-27-8 / Factor VIII
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30. Quesenberry CD, Li C, Chen AH, Zweizig SL, Ball HG 3rd: Primary angiosarcoma of the ovary: a case report of Stage I disease. Gynecol Oncol; 2005 Oct;99(1):218-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the ovary: a case report of Stage I disease.
  • BACKGROUND: There are 20 documented cases of primary ovarian angiosarcoma.
  • Most patients present with metastatic disease and respond poorly to chemotherapy.
  • CASE: We present a case of Stage Ic primary ovarian angiosarcoma treated with 3 cycles of adjuvant MAID chemotherapy.
  • The patient is without evidence of disease 10 months post-operatively.
  • CONCLUSION: A review of the literature indicates a potential role for MAID chemotherapy in the treatment of ovarian angiosarcomas.
  • Detection of Stage I disease appears to confer a better prognosis regardless of the utilization of adjuvant chemotherapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Hemangiosarcoma / drug therapy. Ovarian Neoplasms / drug therapy

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  • (PMID = 16081151.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; NR7O1405Q9 / Mesna; UM20QQM95Y / Ifosfamide; MAID protocol
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31. Hirotsune N, Terada K, Meguro T, Nishino S, Asano T, Manabe T, Toi Y: [Superselective feeder embolization for hemorrhage from cutaneous angiosarcoma in scalp]. No Shinkei Geka; 2005 Oct;33(10):995-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Superselective feeder embolization for hemorrhage from cutaneous angiosarcoma in scalp].
  • The diagnosis of angiosarcoma was confirmed histologically.
  • The early diagnosis by neurosurgeon may lead to improved survival.
  • [MeSH-major] Embolization, Therapeutic / methods. Hemangiosarcoma / complications. Hemorrhage / therapy. Scalp. Skin Neoplasms / complications

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  • (PMID = 16223178.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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32. Isa NM, James DT, Saw TH, Pennisi R, Gough I: Primary angiosarcoma of the thyroid gland with recurrence diagnosed by fine needle aspiration: a case report. Diagn Cytopathol; 2009 Jun;37(6):427-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the thyroid gland with recurrence diagnosed by fine needle aspiration: a case report.
  • Angiosarcoma of the thyroid is a rare and aggressive primary malignant tumor of the thyroid originally reported in patients from the Swiss Alpine region.
  • Diagnosis of this tumor rests mainly on characteristic histopathological features of a malignant vascular tumor supported by immunopositivity for vascular markers e.g., CD31, Factor VIII, and CD34.
  • We describe a case of primary angiosarcoma of the thyroid in a 48-year-old female, who presented with a rapidly enlarging neck mass associated with compressive symptoms.
  • Histologically, the tumor showed poorly differentiated malignant cells with eccentrically-placed nuclei, prominent nucleoli, and intracytoplasmic vacuoles admixed with mixed inflammatory cells.
  • A diagnosis of poorly differentiated malignant tumor consistent with angiosarcoma was made.
  • Second aspiration cytology of the recurrent tumor yielded hypocellular smears containing singularly dispersed atypical cells having eccentrically-placed nuclei with prominent macronucleoli and intracytoplasmic vacuoles within a background of inflammatory cells, consistent with recurrent angiosarcoma.
  • Chemotherapy was started but she succumbed to the disease 7 months after diagnosis.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Hemangiosarcoma / pathology. Thyroid Gland / pathology

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19306411.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31
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33. Ploegmakers MJ, Pruszczynski M, De Rooy J, Kusters B, Veth RP: Angiosarcoma with malignant peripheral nerve sheath tumour developing in a patient with klippel-trénaunay-weber syndrome. Sarcoma; 2005;9(3-4):137-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma with malignant peripheral nerve sheath tumour developing in a patient with klippel-trénaunay-weber syndrome.
  • METHODS: Our patient underwent an above-knee amputation for biopsy-proven malignant vascular tumour, first thought to be a composite hemangio-endothelioma and/or angiosarcoma with lung metastases.
  • RESULTS: In the amputated extremity, a vascular malformation was found with tumour showing various components with foci of angiosarcoma adjacent to diffuse neurofibroma and areas with high-grade malignant peripheral nerve sheath tumour.
  • DISCUSSION: This case describes an angiosarcoma with malignant peripheral nerve sheath tumour developing in a patient with Klippel-Trénaunay-Weber syndrome.

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  • (PMID = 18521421.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2395629
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34. Alvite Canosa M, Alonso Fernández L, Seoane Vigo M, Berdeal Díaz M, Pérez Grobas J, Bouzón Alejandro A, Carral Freire M, de Llano Monelos P, Gómez Freijoso C: [Primary angiosarcoma of the spleen]. Rev Esp Enferm Dig; 2008 Jun;100(6):375-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary angiosarcoma of the spleen].
  • [Transliterated title] Angiosarcoma primario de bazo.
  • [MeSH-major] Hemangiosarcoma. Splenic Neoplasms

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  • (PMID = 18752372.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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35. Centella T, Oliva E, García Andrade I, Lamas MJ, Epeldegui A: [A patient with cardiac angiosarcoma who survived for four years. Case report and literature review]. Rev Esp Cardiol; 2005 Mar;58(3):310-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A patient with cardiac angiosarcoma who survived for four years. Case report and literature review].
  • [Transliterated title] Angiosarcoma cardíaco. Cuatro años de supervivencia. Revisión a propósito de un caso.
  • We describe a 57-year-old woman with a diagnosis of primary cardiac angiosarcoma.
  • She underwent emergency surgery with a preoperative diagnosis of atrial myxoma, and pathological analysis confirmed the diagnosis of cardiac angiosarcoma.
  • [MeSH-major] Heart Neoplasms. Hemangiosarcoma

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  • (PMID = 15766456.001).
  • [ISSN] 0300-8932
  • [Journal-full-title] Revista española de cardiología
  • [ISO-abbreviation] Rev Esp Cardiol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 5
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36. Mallick A, Jain S, Proctor A, Pandey R: Angiosarcoma around a revision total hip arthroplasty and review of literature. J Arthroplasty; 2009 Feb;24(2):323.e17-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma around a revision total hip arthroplasty and review of literature.
  • We report a case of angiosarcoma at the site of a revision total hip arthroplasty.
  • We found only 3 previous reports on angiosarcoma associated with hip arthroplasty in English literature.
  • Association between malignant tumor and hip arthroplasty deserves attention because this surgical procedure is so common that possible risk of a neoplasm should be quantified.
  • Sarcoma is rare, and its possible causation by retained foreign body material has been reported only as single cases.
  • [MeSH-major] Arthroplasty, Replacement, Hip / adverse effects. Hemangiosarcoma / diagnosis. Hip Prosthesis / adverse effects. Skin Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 18617362.001).
  • [ISSN] 1532-8406
  • [Journal-full-title] The Journal of arthroplasty
  • [ISO-abbreviation] J Arthroplasty
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Metals
  • [Number-of-references] 25
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37. Siddaraju N, Soundararaghavan J, Bundele MM, Roy SK: Fine needle aspiration cytology of epithelioid angiosarcoma: a case report. Acta Cytol; 2008 Jan-Feb;52(1):109-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration cytology of epithelioid angiosarcoma: a case report.
  • BACKGROUND: Malignant vascular tumors are rare.
  • Few studies have described cytomorphologic features of hemangioendothelioma and angiosarcoma on fine needle aspiration cytology (FNAC).
  • Malignant vascular tumor with epithelioid morphology can create diagnostic difficulty, as the cytology may simulate that in other nonvascular malignant tumors.
  • We describe epithelioid angiosarcoma, diagnosed on FNAC, in which a differential diagnosis of histiocytosis and inflammatory granulation tissue was considered.
  • FNA resulted in high cellular yield, and smears revealed prominent vascular pattern with endothelial cell atypia and histiocytoid/epithelioid neoplastic cells, occasional mitotic figures and a few cells displaying nuclear grooving.
  • Epithelioid hemangioendothelioma/angiosarcoma, histiocytosis and inflammatory granulation tissue were considered.
  • A cytologic diagnosis of epithelioid angiosarcoma/epithelioid hemangioendothelioma was suggested and confirmed on histopathologic and immunohistochemical examination.
  • CONCLUSION: Cellular aspirates from malignant epithelioid endothelial tumors involving bone may be cytologically mistaken for histiocytosis and, rarely, inflammatory granulation tissue.
  • However, prominent vascular pattern with striking endothelial cell atypia, presence of mitotic figures and careful search for presence of endothelial differentiation are helpful in accurate cytologic diagnosis.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hemangioendothelioma, Epithelioid / diagnosis. Hemangiosarcoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Granulation Tissue / pathology. Histiocytosis / diagnosis. Humans. Immunohistochemistry. Inflammation / diagnosis. Male

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  • (PMID = 18323286.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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38. Kiyozuka Y, Koyama H, Nakata M, Matsuyama T, Nikaido Y, Shimano N, Tsubura A: Diagnostic cytopathology in type II angiosarcoma of the breast: a case report. Acta Cytol; 2005 Sep-Oct;49(5):560-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic cytopathology in type II angiosarcoma of the breast: a case report.
  • BACKGROUND: The rare occurrence of angiosarcoma of the breast is reflected in limited descriptions of fine needle aspiration (FNA) cytomorphologic findings in this neoplasm.
  • We present a case of angiosarcoma of the breast and discuss the pitfalls in diagnostic cytopathology that can potentially lead to incorrect diagnoses in such cases.
  • The overall cytologic diagnosis was inconclusive but suggested phyllodes tumor (of borderline malignancy).
  • Histologic features were consistent with angiosarcoma, a diagnosis that was supported by immunohistochemical studies.
  • CONCLUSION: On FNA smear, 49.1% of isolated atypical cells were positive for the endothelial marker CD34; however, cytomorphologic appearance of these cells resembled that of CD34-negative active mesenchymal cells.
  • Angiosarcoma rarely occurs in the breast, and a definitive diagnosis is difficult based on cytologic examination of hypocellular smears alone.
  • [MeSH-major] Blood Vessels / pathology. Breast Neoplasms / pathology. Hemangiosarcoma / pathology. Mammary Glands, Human / blood supply. Mammary Glands, Human / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Biopsy, Fine-Needle. Endothelial Cells / pathology. Epithelial Cells / pathology. Female. Fibroblasts / pathology. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Mammography. Mastectomy. Middle Aged. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16334037.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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39. Bong AB, Bonnekoh B, Schön MP, Gollnick H: Treatment of scalp angiosarcoma by controlled perfusion of A. carotis externa with pegylated liposomal doxorubicin and intralesional application of pegylated interferon alfa. J Am Acad Dermatol; 2005 Feb;52(2 Suppl 1):20-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of scalp angiosarcoma by controlled perfusion of A. carotis externa with pegylated liposomal doxorubicin and intralesional application of pegylated interferon alfa.
  • BACKGROUND: Angiosarcoma of the scalp is a rare but highly aggressive malignant tumor that differentiates toward vascular endothelial cells and shows a tendency for diffuse, often clinically occult spread.
  • The clinical diagnosis of angiosarcoma was confirmed by histopathology.
  • At 30 months after diagnosis, the patient shows no recurrence of tumor growth.
  • CONCLUSIONS: In combination with intralesional interferon alfa, intra-arterial doxorubicin may be a promising innovative therapeutic option for localized scalp angiosarcoma, a hitherto poorly manageable and aggressive malignant tumor.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Head and Neck Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Scalp. Skin Neoplasms / drug therapy

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  • (PMID = 15692506.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Interferon-alpha; 0 / Liposomes; 0 / Recombinant Proteins; 0 / peginterferon alfa-2b; 30IQX730WE / Polyethylene Glycols; 80168379AG / Doxorubicin; 99210-65-8 / interferon alfa-2b
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40. Mamoon N, Mushtaq S, Hassan U, Rashid R, Khadim MT, Sarfraz T, Waqar MA: Angiosarcoma arising in recurrent phyllodes tumour. Histopathology; 2009 Jun;54(7):913-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma arising in recurrent phyllodes tumour.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology. Neoplasm Recurrence, Local / pathology. Neoplasms, Second Primary / pathology. Phyllodes Tumor / pathology

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  • (PMID = 19635109.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Antigens, CD34
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41. Sibille L, Ilonca D, Oziol E, Gandilhon P, Micheau A, Vernhet-Kovacsik H, Pascal-Ortiz D: FDG PET/CT in aortic angiosarcoma. Clin Nucl Med; 2010 Feb;35(2):134-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] FDG PET/CT in aortic angiosarcoma.
  • [MeSH-major] Aorta / pathology. Fluorodeoxyglucose F18. Hemangiosarcoma / radiography. Hemangiosarcoma / radionuclide imaging

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  • (PMID = 20090470.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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42. Huo L, Lai S, Gladish G, Czerniak BA, Moran CA: Pulmonary artery angiosarcoma: a clinicopathologic and radiological correlation. Ann Diagn Pathol; 2005 Aug;9(4):209-14

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary artery angiosarcoma: a clinicopathologic and radiological correlation.
  • Histologically, a cellular malignant spindle and epithelioid tumor with areas of necrosis and brisk mitotic activity was seen.
  • [MeSH-major] Hemangiosarcoma / pathology. Pulmonary Artery / pathology. Vascular Neoplasms / pathology

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  • (PMID = 16084454.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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43. Wierzbicka-Hainaut E, Guillet G: [Stewart-Treves syndrome (angiosarcoma on lyphoedema): A rare complication of lymphoedema]. Presse Med; 2010 Dec;39(12):1305-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Stewart-Treves syndrome (angiosarcoma on lyphoedema): A rare complication of lymphoedema].
  • [Transliterated title] Syndrome de Stewart-Treves (angiosarcome sur lymphœdème) : complication rare du lymphœdème.
  • [MeSH-major] Lymphedema / complications. Lymphedema / diagnosis
  • [MeSH-minor] Breast Neoplasms / mortality. Breast Neoplasms / surgery. Chronic Disease. Combined Modality Therapy. Female. Hemangiosarcoma / diagnosis. Hemangiosarcoma / etiology. Hemangiosarcoma / mortality. Hemangiosarcoma / therapy. Humans. Lymphangiosarcoma / diagnosis. Lymphangiosarcoma / etiology. Lymphangiosarcoma / mortality. Lymphangiosarcoma / therapy. Mastectomy, Radical. Postoperative Complications / diagnosis. Postoperative Complications / etiology. Postoperative Complications / mortality. Prognosis. Survival Rate

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20970956.001).
  • [ISSN] 2213-0276
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] Stewart Treves syndrome
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44. Contreras AL, Malpica A: Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature. Int J Gynecol Pathol; 2009 Sep;28(5):453-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature.
  • Malignant transformation of this neoplasm is rare and is mostly represented by squamous carcinoma.
  • Less frequently, malignant transformation is represented by a sarcoma.
  • To date, only 5 cases of angiosarcoma arising in a mature cystic teratoma of the ovary have been reported.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 19696615.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
  • [Number-of-references] 23
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45. Haris M, Koulaouzidis A, Chattington P: Scalp angiosarcoma with pulmonary metastases. Intern Med J; 2007 Dec;37(12):833-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scalp angiosarcoma with pulmonary metastases.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Hemangiosarcoma / pathology. Lung Neoplasms / secondary. Scalp. Skin Neoplasms / pathology

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  • (PMID = 18028087.001).
  • [ISSN] 1445-5994
  • [Journal-full-title] Internal medicine journal
  • [ISO-abbreviation] Intern Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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46. Chryssogonidis IA, Vorkas GA, Papadopoulos XA, Dimitriadis AS: Angiosarcoma of right cardiac atrium. JBR-BTR; 2006 May-Jun;89(3):118-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of right cardiac atrium.
  • [MeSH-major] Heart Atria. Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Contrast Media. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 16883751.001).
  • [ISSN] 0302-7430
  • [Journal-full-title] JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)
  • [ISO-abbreviation] JBR-BTR
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
  • [Chemical-registry-number] 0 / Contrast Media
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47. Dagrégorio G, Levillain P, Guillet G: [Angiosarcoma of the scalp: an unusual clinical presentation]. Ann Dermatol Venereol; 2005 Dec;132(12 Pt 1):1038-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiosarcoma of the scalp: an unusual clinical presentation].
  • [Transliterated title] Angiosarcome du cuir chevelu: une présentation clinique inhabituelle.
  • [MeSH-major] Hemangiosarcoma / pathology. Scalp / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male

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  • (PMID = 16446659.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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48. Coumaros D, Tsesmeli N: Epithelioid angiosarcoma in the duodenal bulb. Endoscopy; 2009;41 Suppl 2:E232
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid angiosarcoma in the duodenal bulb.
  • [MeSH-major] Duodenal Neoplasms / pathology. Hemangiosarcoma / secondary

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  • (PMID = 19757369.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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49. Tiwary SK, Singh MK, Prasad R, Sharma D, Kumar M, Shukla VK: Primary angiosarcoma of the breast. Surgery; 2007 Jun;141(6):821-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the breast.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology
  • [MeSH-minor] Adolescent. Breast / pathology. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Ultrasonography, Mammary

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  • (PMID = 17560259.001).
  • [ISSN] 0039-6060
  • [Journal-full-title] Surgery
  • [ISO-abbreviation] Surgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Drexler M, Dolkart O, Amar E, Pritsch T, Dekel S: Late recurrent hemarthrosis following knee arthroplasty associated with epithelioid angiosarcoma of bone. Knee; 2010 Oct;17(5):365-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Late recurrent hemarthrosis following knee arthroplasty associated with epithelioid angiosarcoma of bone.
  • We report a case of recurrent hemarthrosis 1 year following total knee arthroplasty in a patient with no bleeding diathesis, the hemarthrosis was found to be related to, and led to the diagnosis of high grade sarcoma of the proximal tibia.
  • Sarcoma developing in association with a metallic orthopedic prosthesis or hardware is an uncommon, but well-recognized complication.
  • Sarcomas that occur adjacent to orthopaedic prostheses or hardware are of varied types, but are usually osteosarcoma or malignant fibrous histiocytoma.
  • [MeSH-major] Arthroplasty, Replacement, Knee. Bone Neoplasms / diagnosis. Hemarthrosis / etiology. Osteosarcoma / diagnosis. Postoperative Complications

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  • [Copyright] Copyright 2009 Elsevier B.V. All rights reserved.
  • (PMID = 19945286.001).
  • [ISSN] 1873-5800
  • [Journal-full-title] The Knee
  • [ISO-abbreviation] Knee
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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51. Hsu JT, Chen HM, Lin CY, Yeh CN, Hwang TL, Jan YY, Chen MF: Primary angiosarcoma of the spleen. J Surg Oncol; 2005 Dec 15;92(4):312-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the spleen.
  • BACKGROUND AND OBJECTIVES: Primary splenic angiosarcoma is a very rare and aggressive neoplasm with a high metastatic rate and dismal prognosis.
  • METHODS: The records of all cases of primary splenic angiosarcoma treated at Chang Gung Memorial Hospital from April 1991 to July 2004 were retrospectively reviewed.
  • Three patients had distant metastasis to the liver (n = 2), bone (n = 1), bone marrow (n = 1), and small bowel (n = 1) at diagnosis.
  • One patient was disease-free 162 months after splenectomy.
  • CONCLUSIONS: The clinical presentations of splenic angiosarcoma were similar to those of previous reports apart from the higher rate of splenomegaly observed in this study.
  • In contrast to reported pediatric cases, our patient achieved long-term disease-free survival after splenectomy alone.
  • [MeSH-major] Hemangiosarcoma. Splenic Neoplasms
  • [MeSH-minor] Adult. Aged. Child. Disease-Free Survival. Female. Gastrointestinal Hemorrhage / etiology. Hemoperitoneum / etiology. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Splenectomy. Splenic Rupture / etiology. Splenomegaly / etiology. Thrombocytopenia / etiology

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  • [Copyright] 2005 Wiley-Liss, Inc.
  • (PMID = 16299797.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Buschmann A, Lehnhardt M, Toman N, Preiler P, Salakdeh MS, Muehlberger T: Surgical treatment of angiosarcoma of the scalp: less is more. Ann Plast Surg; 2008 Oct;61(4):399-403
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of angiosarcoma of the scalp: less is more.
  • Angiosarcomas (AS) of the scalp are rare tumors with an extremely poor prognosis mostly affecting elderly patients.
  • In view of the difficult diagnosis, an often delayed therapy and the rapid formation of metastases, a time-saving procedure with a low rate of complications should be given preference over other reconstructive methods.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Hemangiosarcoma / surgery. Reconstructive Surgical Procedures / methods. Scalp / surgery. Skin Neoplasms / surgery

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  • (PMID = 18812710.001).
  • [ISSN] 1536-3708
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Mendiz O, Lev G, Valdivieso L, Fava C, Gallucci E, Baldessari E, Favaloro R: Lifesaving kissing stent for pulmonary trunk stenosis due to primary angiosarcoma. Ann Vasc Surg; 2010 Nov;24(8):1135.e9-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lifesaving kissing stent for pulmonary trunk stenosis due to primary angiosarcoma.
  • [MeSH-major] Arterial Occlusive Diseases / therapy. Endovascular Procedures / instrumentation. Hemangiosarcoma / complications. Pulmonary Artery. Stents. Vascular Neoplasms / complications

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  • [Copyright] Copyright © 2010 Annals of Vascular Surgery Inc. Published by Elsevier Inc. All rights reserved.
  • (PMID = 21035708.001).
  • [ISSN] 1615-5947
  • [Journal-full-title] Annals of vascular surgery
  • [ISO-abbreviation] Ann Vasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Nakajima H, Kobayashi J, Matsuda H, Ishibashi-Ueda H: A primary angiosarcoma in the aorta. Interact Cardiovasc Thorac Surg; 2007 Dec;6(6):832-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A primary angiosarcoma in the aorta.
  • We present herein a huge primary sarcoma in the abdominal aorta, which has been reported as extremely rare.
  • [MeSH-major] Aorta / pathology. Arterial Occlusive Diseases / complications. Hemangiosarcoma / diagnosis. Multiple Organ Failure / etiology. Vascular Neoplasms / diagnosis

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  • (PMID = 17699542.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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55. Ahmad Z, Nisa A, Idrees R, Minhas K, Pervez S, Mumtaz K: Hepatic angiosarcoma with metastasis to small intestine. J Coll Physicians Surg Pak; 2008 Jan;18(1):50-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma with metastasis to small intestine.
  • Hepatic angiosarcomas are rare tumours with poor prognosis, with patients usually dying within 6 months.
  • Similarly, primary or metastatic angiosarcomas in small intestine are extremely rare, often present with recurrent gastrointestinal bleeding and anemia, and have an extremely poor prognosis.
  • Both primary or metastatic intestinal angiosarcomas may exhibit epithelioid morphology.
  • [MeSH-major] Hemangiosarcoma / pathology. Ileal Neoplasms / secondary. Intestine, Small / pathology. Jejunal Neoplasms / secondary. Liver Neoplasms / pathology

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  • (PMID = 18452671.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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56. Kuppahally SS, Litwin SE, Michaels AD: Endomyocardial biopsy of right atrial angiosarcoma guided by intracardiac echocardiography. Cardiol Res Pract; 2010;2010:681726

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endomyocardial biopsy of right atrial angiosarcoma guided by intracardiac echocardiography.

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  • [Cites] Eur J Echocardiogr. 2007 Dec;8(6):505-6 [17015040.001]
  • [Cites] J Am Soc Echocardiogr. 2002 May;15(5):475-7 [12019433.001]
  • (PMID = 20585357.001).
  • [ISSN] 2090-0597
  • [Journal-full-title] Cardiology research and practice
  • [ISO-abbreviation] Cardiol Res Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2878669
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57. Leong J, Rascon MA, Kaushik N: Multifocal angiosarcoma of the gastrointestinal tract. Endoscopy; 2008 Sep;40 Suppl 2:E252-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multifocal angiosarcoma of the gastrointestinal tract.
  • [MeSH-major] Duodenal Neoplasms / pathology. Hemangiosarcoma / pathology

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  • (PMID = 18991227.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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58. Tan SM, Tay YK, Liu TT, Mancer K: Cutaneous angiosarcoma associated with the Kasabach-Merritt syndrome. Ann Acad Med Singapore; 2010 Dec;39(12):941-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous angiosarcoma associated with the Kasabach-Merritt syndrome.
  • [MeSH-major] Hemangiosarcoma / etiology

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  • (PMID = 21274494.001).
  • [ISSN] 0304-4602
  • [Journal-full-title] Annals of the Academy of Medicine, Singapore
  • [ISO-abbreviation] Ann. Acad. Med. Singap.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Singapore
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59. Kiluk JV, Yeh KA: Primary angiosarcoma of the breast. Breast J; 2005 Nov-Dec;11(6):517-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary angiosarcoma of the breast.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology

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  • (PMID = 16297124.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Arribas-Garcia I, Domínguez MF, Alcalá-Galiano A, García AF, Valls JC, De Rasche EN: Oral primary angiosarcoma of the lower lip mucosa: report of a case in a 15-year-old boy. Head Neck; 2008 Oct;30(10):1384-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oral primary angiosarcoma of the lower lip mucosa: report of a case in a 15-year-old boy.
  • BACKGROUND: Angiosarcomas are rare soft tissue malignant tumors with dismal prognosis.
  • METHODS AND RESULTS: We present the case of an inferior lip mucosal low-grade angiosarcoma in a 15-year-old boy treated exclusively with surgery.
  • Prompt and accurate diagnosis with adequate imaging modalities and multidisciplinary treatment are crucial for optimal management of these neoplasms.
  • [MeSH-major] Hemangiosarcoma. Lip Neoplasms

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  • [Copyright] Copyright (c) 2008 Wiley Periodicals, Inc. Head Neck 2008.
  • (PMID = 18286486.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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61. Vogt T, Brockmeyer N, Kutzner H, Schöfer H: Short German guidelines: angiosarcoma and Kaposi sarcoma. J Dtsch Dermatol Ges; 2008 May;6 Suppl 1:S19-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Short German guidelines: angiosarcoma and Kaposi sarcoma.
  • [MeSH-major] Dermatology / standards. Hemangiosarcoma / diagnosis. Hemangiosarcoma / therapy. Medical Oncology / standards. Practice Guidelines as Topic. Sarcoma, Kaposi / diagnosis. Sarcoma, Kaposi / therapy. Skin Neoplasms / diagnosis. Skin Neoplasms / therapy

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  • (PMID = 18801138.001).
  • [ISSN] 1610-0387
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] eng; ger
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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62. Patrianakos AP, Parthenakis FI, Drositis I, Nyktari E, Vardas PE: Primary heart angiosarcoma. Hellenic J Cardiol; 2007 Nov-Dec;48(6):364-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary heart angiosarcoma.
  • [MeSH-major] Echocardiography, Doppler, Color / methods. Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Biopsy / methods. Diagnosis, Differential. Fatal Outcome. Humans. Male. Middle Aged

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  • (PMID = 18196659.001).
  • [ISSN] 1109-9666
  • [Journal-full-title] Hellenic journal of cardiology : HJC = Hellēnikē kardiologikē epitheōrēsē
  • [ISO-abbreviation] Hellenic J Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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63. Bacchi CE, Silva TR, Zambrano E, Plaza J, Suster S, Luzar B, Lamovec J, Pizzolitto S, Falconieri G: Epithelioid angiosarcoma of the skin: a study of 18 cases with emphasis on its clinicopathologic spectrum and unusual morphologic features. Am J Surg Pathol; 2010 Sep;34(9):1334-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid angiosarcoma of the skin: a study of 18 cases with emphasis on its clinicopathologic spectrum and unusual morphologic features.
  • We report 18 cases of cutaneous angiosarcoma with predominant or exclusive epithelioid morphology.
  • Microscopically, the tumors were composed of packed polygonal cells with focal evidence of endothelial differentiation.
  • Of the 9 patients available for follow-up, 5 were alive and apparently well, 2 had recurrent disease, and 2 had died of tumor.
  • Our data show that epithelioid cutaneous angiosarcoma may have a broad morphological spectrum, raising interpretive challenges on microscopy.
  • [MeSH-major] Epithelioid Cells / pathology. Hemangiosarcoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 20697249.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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64. Patton KT, Deyrup AT, Weiss SW: Atypical vascular lesions after surgery and radiation of the breast: a clinicopathologic study of 32 cases analyzing histologic heterogeneity and association with angiosarcoma. Am J Surg Pathol; 2008 Jun;32(6):943-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical vascular lesions after surgery and radiation of the breast: a clinicopathologic study of 32 cases analyzing histologic heterogeneity and association with angiosarcoma.
  • In 4 cases, endothelial atypia, consisting of nuclear and nucleolar enlargement, was noted.
  • Of the 21 patients, 17 are alive without disease, 1 is alive with disease, 1 died of breast carcinoma, 1 died of unknown causes, and 1 showed progressive histologic changes in the AVLs over a period of 5 years resulting in a well-differentiated angiosarcoma.
  • Follow-up in 8 patients with VT AVL (2 to 181 mo; mean 40 mo) disclosed that 6 were alive and well, but 2 of the 4 patients whose lesions displayed endothelial atypia had additional complications.
  • One patient underwent a mastectomy that revealed extensive residual AVL and the second developed a high-grade angiosarcoma after 14 months.
  • There seems to be an association of AVL with angiosarcoma that differs depending on the histologic features, with the VT AVLs having the higher risk.
  • In the 2 patients who developed angiosarcoma, morphologic evidence suggested AVLs to be a precursor rather than simply a risk factor.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology. Neoplasms, Radiation-Induced / pathology

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  • (PMID = 18551753.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Lăzureanu C, Baderca F, Burlacu O, Nicodin A: Soft tissue epithelioid angiosarcoma. Rom J Morphol Embryol; 2010;51(4):787-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Soft tissue epithelioid angiosarcoma.
  • The histological and immunohistochemical aspects were indicative for soft tissue epithelioid angiosarcoma, which was misdiagnosed on frozen and HE sections as a carcinoma, because of the cohesiveness and nesting properties of the malignant cells, together with the presence of lymph node metastases.
  • The proliferative activity of the malignant cells, highlighted by Ki-67 antibody, clone MIB 1 was high (30% of malignant cells were positive at HPF).
  • [MeSH-major] Hemangiosarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Diagnostic Errors. Epithelioid Cells / metabolism. Epithelioid Cells / pathology. Humans. Immunohistochemistry. Male. Middle Aged. Thoracic Neoplasms / diagnosis. Thoracic Neoplasms / metabolism. Thoracic Neoplasms / pathology

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  • (PMID = 21103644.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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66. Gudewer E, Hölzle E, Li L: Widespread cutaneous angiosarcoma of the scalp: diagnosis and soft tissue reconstruction with a combined double-muscle-free flap and split-thickness-skin graft. Oral Maxillofac Surg; 2009 Jun;13(2):95-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Widespread cutaneous angiosarcoma of the scalp: diagnosis and soft tissue reconstruction with a combined double-muscle-free flap and split-thickness-skin graft.
  • BACKGROUND: Cutaneous angiosarcoma is a rare vascular tumor, which is usually located in the head and neck region.
  • CASE REPORT: After three punch biopsies, a 67-year-old patient, who had been healthy so far, was diagnosed with a cutaneous multilocated angiosarcoma of the scalp.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Hemangiosarcoma / surgery. Muscle, Skeletal / transplantation. Reconstructive Surgical Procedures / methods. Scalp / surgery. Skin Neoplasms / surgery. Skin Transplantation / methods. Surgical Flaps

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  • (PMID = 19301046.001).
  • [ISSN] 1865-1550
  • [Journal-full-title] Oral and maxillofacial surgery
  • [ISO-abbreviation] Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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67. Comandone A, Boglione A, Pochettino P, Berno E, Inguì M, Papotti M, Borasio P, Maggi G, Brach Del Prever E, Gino G: Primary sarcomas of the lungs and mediastinum: Clinicopathological study and therapy results of Piedmontese Group for Sarcomas. J Clin Oncol; 2009 May 20;27(15_suppl):e21509

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary sarcomas of the lungs and mediastinum: Clinicopathological study and therapy results of Piedmontese Group for Sarcomas.
  • : e21509 Background: Primary sarcomas of the lungs and mediastinum are rare and few data are reported on treatment and results of therapy.
  • Pts characteristics: median age 41 (19-80 y), male/female 19/12; symptoms at diagnosis: dyspnoea (42%), chest and shoulder pain (39%), cough (35%), hemophtoae (13%), discomfort (10%).
  • 5 mediastinal tumours were located as follows: 2 in anterior part, 1 in posterior and 2 in the middle (sarcomas of the heart).
  • 26 lung sarcomas presented as a singular mass in 23 cases and as a metastatic disease in 3.
  • RESULTS: In 20/31 cases the tumour was immediately resected (3 mediastinal masses and 17 lung sarcomas).
  • The histology were: peripheral nerve tumour 7, leiomyosarcoma 4, MFH 2, fibrosarcoma 2, liposarcoma 1, angiosarcoma 2, undifferentiated sarcoma 1, solitary fibrous tumour 2, rhabdomyosarcoma 2, synovialsarcoma 2, pulmonary artery sarcoma 1, pleuropolmonary blastoma 1, malignant hemangiopericytoma 1, mixoid chondrosarcoma 1, ectopic osteosarcoma 1, aggressive fibromatosis 1.
  • Only 4 pts received neoadjuvant chemotherapy, 11 adjuvant CT, 5 exclusive CT + RT for inoperable disease.
  • Of these only 8 are alive (2 with disease).
  • Volume of disease, complete resection and grading are the dominant prognostic factors.
  • CONCLUSIONS: Primary sarcomas of the lungs and mediastinum have a very severe prognosis.

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  • (PMID = 27963441.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Erbersdobler A, Simon R, Hellwinkel OJ, Bokemeyer C, Sauter G, Hu-Lowe D, Levin W, Gallo-Stampino C, Fiedler W: Analysis of expression of TGF-β1 receptor (ALK-1) in normal and tumor tissues by tissue microarrays. J Clin Oncol; 2009 May 20;27(15_suppl):e22044

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Activin-like kinase I (ALK-1) is a class I TGF- β1 receptor which is almost exclusively expressed on endothelial cells.
  • The highest ALK-1 expression rate was found in lung cancer (NSCLC 49%, SCLC 83%), neuroendocrine pancreas tumor (71%), colon cancer (50%), chondrosarcoma 50%, angiosarcoma 40% and NHL (44%).

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  • (PMID = 27963226.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Lahat G, Dhuka AR, Lahat S, Smith KD, Pollock RE, Hunt KK, Ravi V, Lazar AJ, Lev D: Outcome of locally recurrent and metastatic angiosarcoma. Ann Surg Oncol; 2009 Sep;16(9):2502-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Outcome of locally recurrent and metastatic angiosarcoma.
  • BACKGROUND: Angiosarcoma (AS) is a rare soft tissue sarcoma with an enhanced propensity for local and systemic failure.
  • Median disease-specific survival (DSS) was 50 months [95% confidence interval (CI): 25.7-73.5 months].
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Hemangiosarcoma / secondary. Neoplasm Recurrence, Local / pathology. Neoplasms / pathology

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  • (PMID = 19551444.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Hara T, Tsurumi H, Kasahara S, Ogawa K, Takada J, Imai K, Takai K, Kitagawa J, Kiyama S, Imai N, Oyama M, Takami T, Moriwaki H: Long-term survival of a patient with splenic angiosarcoma after resection, high-dose chemotherapy, and autologous peripheral blood stem cell transplantation. Intern Med; 2010;49(20):2253-7
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  • [Title] Long-term survival of a patient with splenic angiosarcoma after resection, high-dose chemotherapy, and autologous peripheral blood stem cell transplantation.
  • Histological examination was typical for angiosarcoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Hemangiosarcoma / therapy. Peripheral Blood Stem Cell Transplantation. Splenectomy. Splenic Neoplasms / therapy

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  • (PMID = 20962445.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Interleukin-3; 0 / Recombinant Proteins; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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71. Osanai T, Tsuchiya T, Sugawara M: Persistent sciatic artery aneurysm associated with the development of angiosarcoma: a case report. Arch Orthop Trauma Surg; 2008 Sep;128(9):937-40
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  • [Title] Persistent sciatic artery aneurysm associated with the development of angiosarcoma: a case report.
  • PSA is known to undergo aneurysmal formation; however, there have been no previous reports of a soft-tissue sarcoma arising from a PSA.
  • The final pathological diagnosis was aneurysmal PSA that focally developed secondary angiosarcoma.
  • [MeSH-major] Aneurysm / complications. Arteries / surgery. Buttocks / blood supply. Hemangiosarcoma / complications. Vascular Neoplasms / complications

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  • (PMID = 18075749.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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72. Holloway CL, Turner AR, Dundas GS: Cutaneous angiosarcoma of the scalp: a case report of sustained complete response following liposomal Doxorubicin and radiation therapy. Sarcoma; 2005;9(1-2):29-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous angiosarcoma of the scalp: a case report of sustained complete response following liposomal Doxorubicin and radiation therapy.
  • Cutaneous angiosarcomas of the head and neck are aggressive cancers with a mean overall survival of 30 months.
  • We add to the literature a case report of a 65-year-old man with a large, >10 cm, unresectable, angiosarcoma of the scalp who was treated with two cycles of liposomal doxorubicin (Caelyx(R)) followed by electron beam radiation therapy (30 Gy in 10 fractions over 2 weeks) who has sustained a complete response with a 4-year follow-up.

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  • (PMID = 18521414.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2395620
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73. Berretta M, Rupolo M, Buonadonna A, Canzonieri V, Brollo A, Morra A, Berretta S, Bearz A, Tirelli U, Frustaci S: Metastatic angiosarcoma of the kidney: a case report with treatment approach and review of the literature. J Chemother; 2006 Apr;18(2):221-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic angiosarcoma of the kidney: a case report with treatment approach and review of the literature.
  • Angiosarcomas are rare soft tissue malignancies.
  • Typically they originate from the skin of the scalp or face, whereas visceral sarcomas are very rare.
  • We report the case of a 67-year-old man affected by a large angiosarcoma of the kidney.
  • Palliative chemotherapy, based on anthracycline and ifosfamide, which are normally used to treat all other high-grade spindle cell sarcomas, was totally inactive.
  • Antiangiogenetic agents are of interest for this disease due to the peculiar origin of the cells of these sarcomas.
  • [MeSH-major] Hemangiosarcoma / drug therapy. Hemangiosarcoma / surgery. Kidney Neoplasms / drug therapy. Kidney Neoplasms / surgery

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  • (PMID = 16736893.001).
  • [ISSN] 1120-009X
  • [Journal-full-title] Journal of chemotherapy (Florence, Italy)
  • [ISO-abbreviation] J Chemother
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Anthracyclines; UM20QQM95Y / Ifosfamide
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74. Good AB, Nascimento A, Welker KM, Arndt CA: Congenital angiosarcoma with transient response to paclitaxel. J Pediatr Hematol Oncol; 2008 Jun;30(6):451-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital angiosarcoma with transient response to paclitaxel.
  • Angiosarcoma is a rare diagnosis with a poor prognosis.
  • We report the first known case of congenital angiosarcoma.
  • We also report a transient response with paclitaxel, an agent that may have a role in unresectable angiosarcoma.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Head and Neck Neoplasms / congenital. Head and Neck Neoplasms / drug therapy. Hemangiosarcoma / congenital. Hemangiosarcoma / drug therapy. Paclitaxel / therapeutic use
  • [MeSH-minor] Diagnosis, Differential. Fatal Outcome. Female. Humans. Immunohistochemistry. Infant. Lymphangioma, Cystic / pathology

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  • (PMID = 18525462.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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75. Kusano N, Nishikawa M, Ito M, Kakemizu N: [An autopsy case of chronic empyema-associated angiosarcoma that presented with a rapidly growing chest wall mass]. Nihon Kokyuki Gakkai Zasshi; 2008 Mar;46(3):248-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [An autopsy case of chronic empyema-associated angiosarcoma that presented with a rapidly growing chest wall mass].
  • Neither CT- nor sonographically guided biopsy yielded a definitive diagnosis.
  • Autopsy revealed angiosarcoma.
  • We should always keep in mind the early diagnosis of malignant tumor and tuberculosis in patients presenting with a chest wall mass and constitutional symptoms during follow-up of chronic tuberculous empyema.
  • [MeSH-major] Empyema, Tuberculous / complications. Hemangiosarcoma / diagnosis. Thoracic Neoplasms / diagnosis

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  • (PMID = 18409575.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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76. Altan E, Arslan C, Dede D, Dogan E, Altundag K: Primary Angiosarcoma of the Breast after Pregnancy. Am Surg; 2010 Aug 01;76(8):115

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary Angiosarcoma of the Breast after Pregnancy.

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  • (PMID = 28958226.001).
  • [ISSN] 1555-9823
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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77. Valbuena JR, Levenback C, Mansfield P, Liu J: Angiosarcoma of the spleen clinically presenting as metastatic ovarian cancer. A case report and review of the literature. Ann Diagn Pathol; 2005 Oct;9(5):289-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the spleen clinically presenting as metastatic ovarian cancer. A case report and review of the literature.
  • Primary angiosarcomas of the spleen are rare and almost always fatal.
  • With no more than 200 cases reported in the literature worldwide, no specific risk factors are strongly associated with the disease.
  • The vascular spaces are lined by endothelial cells with variable degree of atypia.
  • The differential diagnosis includes a variety of benign and malignant vascular proliferations (littoral cell angioma and Kaposi's sarcoma) as well as metastatic tumors.
  • However, histopathologic examination of the specimen showed the tumor to be of a primary angiosarcoma.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Second Primary / pathology. Ovarian Neoplasms / pathology. Splenic Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans


78. Pink D, Rahm J, Schoeler D, Schoenknecht TM, Reichardt P: Activity of paclitaxel in radiation induced and other secondary angiosarcomas. J Clin Oncol; 2009 May 20;27(15_suppl):10578

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Activity of paclitaxel in radiation induced and other secondary angiosarcomas.
  • : 10578 Background: Angiosarcomas (AS) represent 1-2% of adult soft tissue sarcomas and can arise anywhere in the body.
  • Paclitaxel has shown an exceptionally high activity of 75-89% in angiosarcomas of the face and scalp and to a lesser and less consitent degree of 15-58% in other disease locations.
  • We report on a retrospectice single center experience with chemotherapy in 17 patients (pts.) with secondary angiosarcomas (SAS).
  • 12 female patients suffered from angiosarcoma of the breast/thoracic wall following operation and radiation + chemotherapy of a primary breast cancer with an interval of a median of 6 years (range 2-15 years).
  • 3 pts. remain free of disease.
  • All 14 patients with recurrent/metastatic disease were treated with chemotherapy.
  • Responses were 8 PR with a median PFS of 6 months (range 3-23 months), and 1 SD (PFS 4 months) with a disease control rate of 75%.
  • CONCLUSIONS: Paclitaxel shows high activity in SAS, comparable to the results in face and scalp angiosarcomas and can be considered a standard treatment option.

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  • (PMID = 27963758.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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79. Pfeiffer DF, Bode-Lesniewska B: Fine needle aspiration biopsy diagnosis of angiosarcoma after breast-conserving therapy for carcinoma supported by use of a cell block and immunohistochemistry. Acta Cytol; 2006 Sep-Oct;50(5):553-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration biopsy diagnosis of angiosarcoma after breast-conserving therapy for carcinoma supported by use of a cell block and immunohistochemistry.
  • BACKGROUND: Angiosarcoma is a rare malignant soft tissue tumor occurring at various sites as either a primary or secondary event.
  • Primary angiosarcoma of the breast is an unusual tumor, counting for 1 in 1700-2,000 primary malignant tumors of this organ.
  • An increasing number of secondary angiosarcomas involving skin and breast.
  • CASE: Angiosarcoma arose 6 years after breast-conserving therapy for invasive carcinoma in a 69-year-old woman.
  • Fine needle aspiration of several small, reddish, intradermal nodules over the treated area revealed malignant cells with an endothelial immunophenotype in the cel block, yielding the diagnosis of angiosarcoma, subsequently confired in a mastectomy speciman.
  • CONCLUSION: Fine needle aspiration, supported by ancillary techniques, such as cell block and immunohistochemistry, allows the cytologic diagnosis of an angiosarcoma and differentiates it from a carcinoma recurrence.
  • [MeSH-major] Breast / pathology. Breast Neoplasms / diagnosis. Carcinoma, Ductal, Breast / diagnosis. Hemangiosarcoma / diagnosis. Neoplasms, Second Primary / diagnosis. Radiotherapy / adverse effects
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Biopsy, Fine-Needle. Cell Nucleus / pathology. Diagnosis, Differential. Epithelial Cells / pathology. Female. Humans. Immunohistochemistry / methods. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 17017445.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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80. Hayn MH, Bastacky S, Franks ME: Epididymal angiosarcoma. Urology; 2007 Mar;69(3):576.e5-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epididymal angiosarcoma.
  • Sarcomas are rare and account for approximately 1% of all malignancies.
  • The subtype angiosarcoma is derived from vascular and lymphatic tissue and generally has a poor prognosis.
  • Prior radiation therapy is a known risk factor for the development of angiosarcomas.
  • We present what we believe to be the first case of an angiosarcoma arising in the epididymis in an 80-year-old man who presented with right scrotal swelling.
  • [MeSH-major] Epididymis. Genital Neoplasms, Male / surgery. Hemangiosarcoma / surgery. Neoplasms, Second Primary / surgery

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  • (PMID = 17382180.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Carnero López B, Fernández Pérez I, Carrasco Alvarez JA, Lázaro Quintela ME, López Jato C, Jorge Fernández M, Gentil González M, Vázquez Tuñas L, Castellanos Díez J: Renal primary angiosarcoma. Clin Transl Oncol; 2007 Dec;9(12):806-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Renal primary angiosarcoma.
  • Angiosarcomas account for 2% of all soft tissue sarcomas and of them, primary renal angiosarcomas represent 1%.
  • We report the second case to be described in a middle-aged female, with pulmonary metastases at diagnosis, and fatal outcome despite surgery and chemotherapy.
  • [MeSH-major] Hemangiosarcoma / pathology. Kidney Neoplasms / pathology

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  • (PMID = 18158986.001).
  • [ISSN] 1699-048X
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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82. Ayadi L, Khabir A: Pediatric angiosarcoma of soft tissue: a rare clinicopathologic entity. Arch Pathol Lab Med; 2010 Mar;134(3):481-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric angiosarcoma of soft tissue: a rare clinicopathologic entity.
  • Angiosarcomas are rare tumors that predominantly affect adults and elderly patients.
  • Although angiosarcomas are well described in a variety of clinical settings, they have been poorly studied in children and little is known about their biology, natural history, or optimal treatment.
  • Childhood angiosarcomas are exceedingly rare.
  • The differential diagnosis includes Kaposi sarcoma, epithelioid hemangioendothelioma, hemangiopericytoma, and spindle cell hemangioendothelioma whose prognosis is different.
  • Malignant vascular tumors are rare in children in the first 2 decades of life and when they do occur they seem to be more aggressive than in adults.
  • Pathologic diagnosis is difficult particularly in poorly differentiated angiosarcomas requiring immunohistochemical study to confirm vascular differentiation.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Hemangiosarcoma / pathology. Mediastinal Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / analysis. Child. Child, Preschool. Combined Modality Therapy. Diagnosis, Differential. Female. Hemangioendothelioma, Epithelioid / diagnosis. Hemangiopericytoma / diagnosis. Humans. Infant. Male. Prognosis. Sarcoma, Kaposi / diagnosis

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  • (PMID = 20196675.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 17
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83. Bernardos L, García Marín A, Rey Valcárcel C, Martín Gil J, Turégano Fuentes F: [Hepatic angiosarcoma]. Rev Esp Enferm Dig; 2008 Dec;100(12):804-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hepatic angiosarcoma].
  • [Transliterated title] Angiosarcoma hepático.
  • [MeSH-major] Hemangiosarcoma / pathology. Liver Neoplasms / pathology

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  • (PMID = 19222346.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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84. Afonso PV, Antunes MJ: Primary cardiac angiosarcoma. Extended resection of the right atrial wall. Case report. Rev Port Cardiol; 2007 Nov;26(11):1189-94

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac angiosarcoma. Extended resection of the right atrial wall. Case report.
  • We report the case of a 51-year-old patient who presented with tiredness and leg swelling, with recurrent pericardial effusion; a right atrial tumor, suggestive of sarcoma, was diagnosed, which responded poorly to chemotherapy.
  • She is currently well and asymptomatic, with no signs of recurrence ten months after surgery and nearly 24 months after the initial diagnosis.
  • [MeSH-major] Heart Neoplasms / surgery. Hemangiosarcoma / surgery

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  • (PMID = 18297840.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Portugal
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85. Lo Presti M, Mazzella C, Monfrecola A, Falleti J: Angiosarcoma mimicking rhinophyma. Dermatol Res Pract; 2010;2010:365173

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma mimicking rhinophyma.
  • During that time the patient underwent several dermatological consultations, and all produced the same diagnosis: rhinophyma.
  • Punch biopsy was performed, and histopathology and immunohistochemical studies were consistent with cutaneous angiosarcoma.
  • This is the report of a face angiosarcoma with an unusual and very deceptive clinical presentation.

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  • [Cites] Clin Exp Dermatol. 2009 Oct;34(7):e227-8 [19302586.001]
  • [Cites] Dermatol Surg. 2009 Apr;35(4):679-84 [19415795.001]
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  • (PMID = 20631905.001).
  • [ISSN] 1687-6113
  • [Journal-full-title] Dermatology research and practice
  • [ISO-abbreviation] Dermatol Res Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2902059
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86. Mücke T, Deppe H, Wolff KD, Kesting MR: Gingival angiosarcoma mimicking necrotizing gingivitis. Int J Oral Maxillofac Surg; 2010 Aug;39(8):827-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gingival angiosarcoma mimicking necrotizing gingivitis.
  • The authors present a case of a rare highly malignant condition that initially appeared clinically and histologically to be the relatively common and benign condition necrotizing gingivitis.
  • Conditions that do not follow the expected clinical course mandate further investigation because rare malignant disease is not foremost in the mind of dentists and oral and maxillofacial surgeons.
  • [MeSH-major] Gingival Neoplasms / pathology. Gingivitis, Necrotizing Ulcerative / pathology. Hemangiosarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Necrosis

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  • [Copyright] Copyright 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20359867.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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87. Keenan N, Davies S, Sheppard MN, Maceira A, Serino W, Mohiaddin RH: Angiosarcoma of the right atrium: a diagnostic dilemma. Int J Cardiol; 2006 Nov 18;113(3):425-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the right atrium: a diagnostic dilemma.
  • Angiosarcomas of the heart are rare and usually fatal.
  • We describe a case where cardiovascular magnetic resonance imaging was crucial in making the diagnosis.
  • Surgical resection was performed and the diagnosis was confirmed by histology.
  • [MeSH-major] Heart Atria. Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 16310265.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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88. Méndez-Sánchez N, Roldán-Valadéz E, Motola-Kuba D, Almeda-Valdés P, Uribe M: Hepatic angiosarcoma. Ann Hepatol; 2005 Jan-Mar;4(1):60-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Liver Neoplasms / diagnosis

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  • (PMID = 15798664.001).
  • [ISSN] 1665-2681
  • [Journal-full-title] Annals of hepatology
  • [ISO-abbreviation] Ann Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Mexico
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89. Kluger N, Girard C, Boissier E, Sibille L, Mariano-Goulart D, Guillot B: Metastatic cutaneous angiosarcoma complicated with severe thrombocytopenia. Eur J Dermatol; 2010 Sep-Oct;20(5):662-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic cutaneous angiosarcoma complicated with severe thrombocytopenia.
  • [MeSH-major] Head and Neck Neoplasms / complications. Hemangiosarcoma / complications. Hemangiosarcoma / secondary. Scalp. Skin Neoplasms / complications. Skin Neoplasms / pathology. Thrombocytopenia / complications
  • [MeSH-minor] Aged. Bone Neoplasms / secondary. Disease Progression. Fatal Outcome. Humans. Lung Neoplasms / secondary. Lymphatic Metastasis. Parotid Neoplasms / secondary

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  • (PMID = 20634170.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] France
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90. Berry MF, Williams M, Welsby I, Lin S: Cardiac angiosarcoma presenting with right coronary artery pseudoaneurysm. J Cardiothorac Vasc Anesth; 2010 Aug;24(4):633-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac angiosarcoma presenting with right coronary artery pseudoaneurysm.
  • [MeSH-major] Aneurysm, False / diagnosis. Coronary Vessels / pathology. Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male

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  • (PMID = 19525126.001).
  • [ISSN] 1532-8422
  • [Journal-full-title] Journal of cardiothoracic and vascular anesthesia
  • [ISO-abbreviation] J. Cardiothorac. Vasc. Anesth.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Requena L, Santonja C, Stutz N, Kaddu S, Weenig RH, Kutzner H, Menzel T, Cerroni L: Pseudolymphomatous cutaneous angiosarcoma: a rare variant of cutaneous angiosarcoma readily mistaken for cutaneous lymphoma. Am J Dermatopathol; 2007 Aug;29(4):342-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pseudolymphomatous cutaneous angiosarcoma: a rare variant of cutaneous angiosarcoma readily mistaken for cutaneous lymphoma.
  • Cutaneous angiosarcoma is probably the most malignant neoplasm involving the skin.
  • Three clinical variants of cutaneous angiosarcoma are recognized, including angiosarcoma of the scalp and face of elderly patients, angiosarcoma associated with chronic lymphedema, and postirradiation angiosarcoma.
  • Histopathologically, these three variants of angiosarcoma show similar features, which consist of poorly circumscribed, irregularly dilated, and anastomosing vascular channels lined by prominent endothelial cells that dissect through the dermis.
  • Focally, neoplastic endothelial cells show large, hyperchromatic, and pleomorphic nuclei, protruding within vascular lumina and creating small papillations.
  • In rare instances, cutaneous angiosarcomas may exhibit prominent inflammatory infiltrate, and the neoplasm may be mistaken for an inflammatory process, both from clinical and histopathologic points of view.
  • We describe four examples of cutaneous angiosarcomas with dense lymphocytic infiltrates involving the neoplasm.
  • The neoplastic endothelial cells expressed immunoreactivity for the CD31, CD34, podoplanin, Prox-1, Lyve-1, and D2-40.
  • We discuss the possible relationship between neoplastic endothelial lymphatic cells and reactive lymphocytes.
  • Cutaneous angiosarcoma with prominent lymphocytic infiltrate may be readily mistaken for cutaneous follicle center cell lymphoma or cutaneous pseudolymphoma.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Lymphoma / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Breast Neoplasms / diagnosis. Diagnosis, Differential. Endothelial Cells / pathology. Endothelium, Vascular / pathology. Facial Neoplasms / diagnosis. Female. Humans. Lymphocytes / pathology. Lymphoma, Follicular / diagnosis. Male. Middle Aged. Neovascularization, Pathologic / pathology. Pseudolymphoma / diagnosis. Scalp / pathology. Skin Diseases / diagnosis

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  • (PMID = 17667166.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Uno H, Sasaki M, Osamura K, Ohtoshi S, Nakada T, Iijima M: Angiosarcoma (Stewart-Treves syndrome): palliative role of Mohs' ointment. J Dermatol; 2010 Sep;37(9):852-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma (Stewart-Treves syndrome): palliative role of Mohs' ointment.
  • [MeSH-minor] Aged. Antigens, CD31 / analysis. Antigens, CD34 / analysis. Fatal Outcome. Female. Hemangiosarcoma / drug therapy. Hemangiosarcoma / pathology. Humans. Lymphangiosarcoma / drug therapy. Lymphangiosarcoma / pathology

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  • (PMID = 20883379.001).
  • [ISSN] 1346-8138
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Antigens, CD34; 0 / Chlorides; 0 / Ointments; 0 / Zinc Compounds; 86Q357L16B / zinc chloride; Stewart Treves syndrome
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93. Seok JY, Kim YB: [Primary angiosarcoma of the liver]. Korean J Hepatol; 2009 Jun;15(2):216-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary angiosarcoma of the liver].
  • [MeSH-major] Hemangiosarcoma / pathology. Liver Neoplasms / pathology

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  • (PMID = 19581774.001).
  • [ISSN] 1738-222X
  • [Journal-full-title] The Korean journal of hepatology
  • [ISO-abbreviation] Korean J Hepatol
  • [Language] kor
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Antigens, CD34
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94. Kaushik M, Alla VM, Pasupuleti S, Hunter C, Shatat L, Hunter WJ: Cardiac angiosarcoma and recurrent pericardial effusion. South Med J; 2010 Aug;103(8):849-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac angiosarcoma and recurrent pericardial effusion.
  • [MeSH-major] Heart Neoplasms / complications. Hemangiosarcoma / complications. Pericardial Effusion / etiology

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  • (PMID = 20622718.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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95. Holtan SG, Allen RD, Henkel DM, Kamal AH, Novak GD, O'Cochlain F, Chandrasekaran K, Mullany CJ, Wright RS: Angiosarcoma of the pericardium presenting as hemorrhagic pleuropericarditis, cardiac tamponade, and thromboembolic phenomena. Int J Cardiol; 2007 Jan 31;115(1):e8-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the pericardium presenting as hemorrhagic pleuropericarditis, cardiac tamponade, and thromboembolic phenomena.
  • [MeSH-major] Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Cardiac Tamponade / diagnosis. Cardiac Tamponade / etiology. Diagnosis, Differential. Fatal Outcome. Female. Hemorrhage / etiology. Humans. Middle Aged. Pericarditis / diagnosis. Pericarditis / etiology. Pericardium. Pleurisy / diagnosis. Pleurisy / etiology. Thromboembolism / diagnosis. Thromboembolism / etiology

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  • (PMID = 16904210.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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96. Fuller CK, Charlson JA, Dankle SK, Russell TJ: Dramatic improvement of inoperable angiosarcoma with combination paclitaxel and bevacizumab chemotherapy. J Am Acad Dermatol; 2010 Oct;63(4):e83-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dramatic improvement of inoperable angiosarcoma with combination paclitaxel and bevacizumab chemotherapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Facial Neoplasms / drug therapy. Facial Neoplasms / pathology. Hemangiosarcoma / drug therapy. Hemangiosarcoma / pathology

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  • (PMID = 20846560.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 2S9ZZM9Q9V / Bevacizumab; P88XT4IS4D / Paclitaxel
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97. van der Lee C, Klootwijk PJ, van Geuns RJ, Maat LP, den Bakker MA: Angiosarcoma of the right atrium presenting as collapse. Int J Cardiol; 2009 Feb 6;132(1):e17-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the right atrium presenting as collapse.
  • Angiosarcoma is the most common cardiac malignancy, which often arises as a mass in the right atrium.
  • We describe a young patient with collapse due to pericardial effusion caused by a primary cardiac angiosarcoma.
  • The case is an example of the difficulties and dilemmas which may be encountered in assessing the diagnosis of cardiac angiosarcoma.
  • [MeSH-major] Heart Neoplasms / complications. Hemangiosarcoma / complications. Pericardial Effusion / etiology. Unconsciousness / etiology
  • [MeSH-minor] Adult. Diagnosis, Differential. Dizziness. Dyspnea. Fatal Outcome. Heart Atria. Humans. Lung Neoplasms / radiography. Lung Neoplasms / secondary. Male. Pericardiocentesis

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  • (PMID = 18031846.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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98. Lim RF, Goei R: Best cases from the AFIP: angiosarcoma of the breast. Radiographics; 2007 Oct;27 Suppl 1:S125-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Best cases from the AFIP: angiosarcoma of the breast.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology

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  • (PMID = 18180222.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Higashiyama S, Kawabe J, Hayashi T, Kurooka H, Oe A, Kawamura E, Shiomi S: Effectiveness of preoperative PET examination of huge angiosarcoma of the heart. Clin Nucl Med; 2009 Feb;34(2):99-102

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effectiveness of preoperative PET examination of huge angiosarcoma of the heart.
  • [MeSH-major] Heart Neoplasms / radionuclide imaging. Heart Neoplasms / surgery. Hemangiosarcoma / radionuclide imaging. Hemangiosarcoma / surgery. Preoperative Care

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  • (PMID = 19352263.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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100. Tanabe K, Masuzawa M, Aki R, Masuzawa M, Arai S, Hayakawa K, Katsuoka K, Kobayashi T: Angiosarcoma of the scalp with metastasis to the gingiva. Acta Derm Venereol; 2008;88(5):512-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the scalp with metastasis to the gingiva.
  • [MeSH-major] Gingival Neoplasms / secondary. Hemangiosarcoma / pathology. Hemangiosarcoma / secondary. Scalp / pathology. Skin Neoplasms / pathology

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  • (PMID = 18779896.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Sweden
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