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Items 1 to 100 of about 1089
1. Mundi A: Images in clinical medicine. Large atrial myxoma. N Engl J Med; 2009 Nov 26;361(22):e51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Images in clinical medicine. Large atrial myxoma.
  • [MeSH-major] Heart Neoplasms / ultrasonography. Myxoma / ultrasonography

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  • (PMID = 19940296.001).
  • [ISSN] 1533-4406
  • [Journal-full-title] The New England journal of medicine
  • [ISO-abbreviation] N. Engl. J. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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2. Lewis DM: Multilocular radiolucent lesions of the jaws. Odontogenic myxoma. J Okla Dent Assoc; 2010 Sep;101(6):28-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multilocular radiolucent lesions of the jaws. Odontogenic myxoma.
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Mandibular Diseases / diagnosis. Odontogenic Cysts / diagnosis. Young Adult

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  • (PMID = 21038804.001).
  • [ISSN] 0164-9442
  • [Journal-full-title] Journal - Oklahoma Dental Association
  • [ISO-abbreviation] J Okla Dent Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Yoshida K, Kawase T, Tomita T, Ogawa K, Kawana H, Yago K, Asanami S: Surgical strategy for tumors located in or extending from the intracranial space to the infratemporal fossa-Advantages of the transcranial approach (zygomatic infratemporal fossa approach) and the indications for a combined transcranial and transcervical approach-. Neurol Med Chir (Tokyo); 2009 Dec;49(12):580-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In five of these 9 cases (2 schwannomas, 1 myxoma, 1 chondrosarcoma, and 1 malignant peripheral nerve sheath tumor), the tumors were localized in the infratemporal fossa, and in the other 4 cases (2 meningiomas, 1 glioblastoma, and 1 ameloblastoma), the tumors extended to both the intracranial space and the infratemporal fossa.
  • [MeSH-minor] Adult. Aged. Cranial Nerve Neoplasms / pathology. Cranial Nerve Neoplasms / radiography. Cranial Nerve Neoplasms / surgery. Cranial Nerves / anatomy & histology. Cranial Nerves / pathology. Cranial Nerves / surgery. Disease Progression. Female. Humans. Magnetic Resonance Imaging. Male. Meningioma / pathology. Meningioma / radiography. Meningioma / surgery. Middle Aged. Neck / anatomy & histology. Neck / surgery. Neoplasm Invasiveness / pathology. Neoplasm Invasiveness / physiopathology. Orbit / anatomy & histology. Orbit / surgery. Osteotomy / methods. Postoperative Complications / prevention & control. Retrospective Studies. Sarcoma / pathology. Sarcoma / radiography. Sarcoma / surgery. Skull Base Neoplasms / pathology. Skull Base Neoplasms / radiography. Skull Base Neoplasms / surgery. Tomography, X-Ray Computed. Treatment Outcome. Young Adult. Zygoma / anatomy & histology. Zygoma / surgery


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4. Sasaki A, Horikawa Y, Suwa T, Enya M, Kawachi S, Takeda J: Case report of familial Carney complex due to novel frameshift mutation c.597del C (p.Phe200LeufsX6) in PRKAR1A. Mol Genet Metab; 2008 Nov;95(3):182-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Carney complex is an autosomal dominantly inherited disease characterized by skin pigmentation, myxoma, primary pigmented nodular adrenocortical disease (PPNAD), and acromegaly.
  • Based on family history of acromegaly (mother and sister) and the fact that the combination of both diseases is very rare, genetic diagnosis involving Carney complex was considered to be appropriate.
  • Even family members with the same mutation can show distinct phenotypes, suggesting that Carney complex is a multifactorial disorder comprising various genetic and environmental factors.
  • Genetic diagnosis makes it possible to prepare more effective therapeutic strategies for patients and gene carriers and to avoid unnecessary tests for non-carriers in the family of the patient.

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  • (PMID = 18760947.001).
  • [ISSN] 1096-7206
  • [Journal-full-title] Molecular genetics and metabolism
  • [ISO-abbreviation] Mol. Genet. Metab.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / PRKAR1A protein, human
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5. Stanford MM, McFadden G, Karupiah G, Chaudhri G: Immunopathogenesis of poxvirus infections: forecasting the impending storm. Immunol Cell Biol; 2007 Feb-Mar;85(2):93-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although smallpox was eradicated almost 30 years ago, it is not understood why the mortality rates associated with the disease were high, why some patients recovered, and what constitutes an effective host response against infection.
  • As variola virus infects only humans, our current understanding of poxvirus infections comes largely from historical clinical data from smallpox patients and from animal studies using closely related viruses such as ectromelia, myxoma and monkeypox.
  • Disease pathogenesis is also a function of both host and viral factors.
  • Poxviruses are not only cytopathic, causing host tissue damage, but also encode an array of immunomodulatory molecules that affect the severity of disease.
  • There is growing evidence that many of the symptoms associated with serious poxvirus infections are a result of a 'cytokine storm' or sepsis and that this may be the underlying cause of pathology.
  • [MeSH-minor] Animals. Cytokines / physiology. Disease Models, Animal. Humans. Models, Biological. Poxviridae / immunology. Poxviridae / pathogenicity. Sepsis / immunology. Sepsis / prevention & control

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  • (PMID = 17228320.001).
  • [ISSN] 0818-9641
  • [Journal-full-title] Immunology and cell biology
  • [ISO-abbreviation] Immunol. Cell Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Cytokines
  • [Number-of-references] 128
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6. Tamaki M, Tanaka T, Matsumoto K, Nakamura E: [Giant left atrial myxoma with ossification on having a fever; report of a case]. Kyobu Geka; 2009 Aug;62(9):830-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant left atrial myxoma with ossification on having a fever; report of a case].
  • The tumor was diagnosed as myxoma with ossification by histopathological examination.
  • We consider our case as extremely rare, because it revealed giant left atrial myxoma with ossification and mitral insufficiency at the same time.
  • [MeSH-major] Heart Neoplasms / diagnosis. Myxoma / diagnosis

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  • (PMID = 19670789.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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7. Heitner JF, Klem I, Alexander K, Thomson L, Meine TJ, Patel MR, Haq SA, Shah DJ, Kim RJ: The case of the disappearing myxoma. J Cardiovasc Magn Reson; 2005;7(5):841-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The case of the disappearing myxoma.
  • We present a case demonstrating the utility of cardiovascular magnetic resonance (CMR) in the diagnosis of a cardiac mass.
  • A 70-year-old female who presented with chest pressure and left sided jaw pain was found to have a cardiac mass on transthoracic and transesophageal echocardiography that was diagnosed as an atrial myxoma.
  • A cardiac magnetic resonance test determined the mass to be more consistent with a thrombus than a myxoma through a stepwise approach using multiple pulse sequences.
  • Thus, unwarranted and potentially risky thoracic surgery was avoided by the incorporation of a systematic evaluation by cardiac MRI.
  • [MeSH-major] Heart Neoplasms / pathology. Magnetic Resonance Imaging. Myxoma / pathology
  • [MeSH-minor] Aged. Atrial Appendage / pathology. Cardiomyopathies / pathology. Diagnosis, Differential. Echocardiography. Echocardiography, Transesophageal. Female. Humans. Pulmonary Veins / pathology. Thrombosis / pathology

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  • (PMID = 16353446.001).
  • [ISSN] 1097-6647
  • [Journal-full-title] Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
  • [ISO-abbreviation] J Cardiovasc Magn Reson
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Sánchez-Fructuoso A, Conesa J, Perez Flores I, Ridao N, Calvo N, Prats D, Rodríguez A, Barrientos A: Conversion to sirolimus in renal transplant patients with tumors. Transplant Proc; 2006 Oct;38(8):2451-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: This prospective study of 29 patients included 2 patients with skin cancer (1 melanoma and 1 squamous cell carcinoma) and 27 patients who developed other tumors: lung (n = 6), prostate (n = 4), lymphoma (n = 2), colon adenocarcinoma (n = 2), kidney (n = 2), Kaposi sarcoma (n = 2), urothelium (n = 1), parotid (n = 1), larynx (n = 1), gastric (n = 1), breast (n = 1), tongue (n = 1), liver (n = 1), xanthoastrocytoma (n = 1), and aggressive angiomyxoma of the perineum (n = 1).

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  • (PMID = 17097964.001).
  • [ISSN] 0041-1345
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; AYI8EX34EU / Creatinine; W36ZG6FT64 / Sirolimus
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9. Feiz-Erfan I, Han PP, Spetzler RF, Porter RW, Klopfenstein JD, Ferreira MA, Beals SP, Joganic EF: Exposure of midline cranial base without a facial incision through a combined craniofacial-transfacial procedure. Neurosurgery; 2005 Jan;56(1 Suppl):28-35; discussion 28-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Between 1992 and 1998, eight patients underwent surgery for five different anterior cranial base pathological findings: four angiofibromas, one mesenchymal chondrosarcoma, one esthesioneuroblastoma, one odontogenic myxoma, and one encephalocele.
  • In all cases, the surgical exposure consisted of a bicoronal scalp incision with a bifrontal craniotomy and fronto-orbitonasal osteotomy, and then a sublabial incision for transmaxillary exposure.

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  • (PMID = 15799790.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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10. de Almeida LA, Hueb JC, de Moraes Silva MA, Bazan R, Estrozi B, Raffin CN: Cerebral ischemia as initial neurological manifestation of atrial myxoma: case report. Arq Neuropsiquiatr; 2006 Sep;64(3A):660-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebral ischemia as initial neurological manifestation of atrial myxoma: case report.
  • Cerebral ischemia is the first clinical manifestation in 1/3 of cases of atrial myxomas.
  • Although almost half of patients with atrial myxoma show changes at neurological exam, non-hemorrhagic cerebral infarction is seen in computed tomography in practically all cases.
  • We present the case of a 40 year-old woman whose first clinical manifestation of atrial myxoma was an ischemic stroke.
  • We point out to the possibility of silent cerebral infarction in atrial myxoma patients.
  • [MeSH-major] Heart Neoplasms / complications. Myxoma / complications. Stroke / etiology

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  • (PMID = 17119814.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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11. Narendra H, Ray S, Rao L, Geetha V: Malignant extrarenal rhabdoid tumor of the vulva in an adult. J Cancer Res Ther; 2010 Jan-Mar;6(1):82-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Most common vulvar sarcomas are leiomyosarcomas, malignant fibrohistiocytomas, and aggressive angiomyxomas.
  • MRT of the vulva is a rare and very aggressive neoplasm.
  • We are reporting the 11 th case who remains disease free 30 months following surgery and radiotherapy till the time of reporting.

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  • (PMID = 20479553.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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12. Becker R P, Frangini S P, Arnaiz G P: [Recurrent left atrial myxoma. Report of a case in a 2 year-old boy]. Rev Med Chil; 2006 May;134(5):635-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Recurrent left atrial myxoma. Report of a case in a 2 year-old boy].
  • [Transliterated title] Mixoma auricular izquierdo recurrente en niño de 2 años.
  • We report a two year-old boy, who presented a recurrent left atrial myxoma.
  • The tumor was uneventfully removed and the pathological examination confirmed a myxoma.
  • He was successfully operated again, remaining free of a new recurrence after 3 years of follow up.
  • [MeSH-major] Heart Neoplasms / surgery. Myxoma / surgery. Neoplasm Recurrence, Local / surgery
  • [MeSH-minor] Child, Preschool. Heart Atria / pathology. Heart Atria / surgery. Heart Atria / ultrasonography. Humans. Male. Neoplasm, Residual / pathology. Neoplasm, Residual / surgery. Treatment Outcome

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  • (PMID = 16802057.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Chile
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13. Betz CS, Janda P, Arbogast S, Leunig A: [Myxoma and myxoid chondrosarcoma of the nasal septum: two case reports]. HNO; 2007 Jan;55(1):51-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Myxoma and myxoid chondrosarcoma of the nasal septum: two case reports].
  • Myxoid neoplasms are histopathologically divided into true myxomas and other tumors of myxomatous character.
  • In the following two case reports, the unusual findings of a myxoma and a myxoid chondrosarcoma of the nasal septum are presented and discussed.
  • The histopathological diagnosis was myxoma in the first and myxoid chondrosarcoma in the second patient.
  • [MeSH-minor] Aged, 80 and over. Female. Humans. Middle Aged. Myxoma

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  • (PMID = 16528507.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 20
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14. Mandal S, Dhingra K, Roy S, Khurana N: Aggressive angiomyxoma of the vulva presenting as a pedunculated swelling. Indian J Pathol Microbiol; 2008 Apr-Jun;51(2):259-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive angiomyxoma of the vulva presenting as a pedunculated swelling.
  • Aggressive angiomyxoma is a rare, locally aggressive soft tissue tumor that has high propensity for local recurrence.
  • We describe a case of a 22-year-old young pregnant patient presenting with a large pedunculated swelling on the left labia majora.
  • [MeSH-major] Myxoma / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Invasiveness / pathology. Pregnancy

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  • (PMID = 18603701.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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16. Barlis P, Lim EJ, Gow PJ, Seevanayagam S, Calafiore P, Chan RK: Giant cardiac myxoma. Heart Lung Circ; 2007 Oct;16(5):389-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant cardiac myxoma.
  • Although cardiac myxomas remain an uncommon group of malignancies, they are the most common form of primary cardiac tumour.
  • We present a case of a 46-year-old man with chronic abdominal pain and discuss a number of diagnostic challenges that were confronted up until a definitive diagnosis of cardiac myxoma was made.
  • [MeSH-major] Heart Neoplasms / surgery. Heart Neoplasms / ultrasonography. Myxoma / surgery. Myxoma / ultrasonography

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  • (PMID = 17446132.001).
  • [ISSN] 1443-9506
  • [Journal-full-title] Heart, lung & circulation
  • [ISO-abbreviation] Heart Lung Circ
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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17. Barrett JW, Shun Chang C, Wang G, Werden SJ, Shao Z, Barrett C, Gao X, Belsito TA, Villenevue D, McFadden G: Myxoma virus M063R is a host range gene essential for virus replication in rabbit cells. Virology; 2007 Apr 25;361(1):123-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxoma virus M063R is a host range gene essential for virus replication in rabbit cells.
  • The myxoma virus M063R gene product exhibits some sequence similarity to the poxvirus host range gene, C7L, of vaccinia virus.
  • To address the potential host range function of the M063R gene product in rabbits, a deletion mutant of myxoma virus (vMyx63KO) was generated and characterized. vMyx63KO replicated to normal titre levels and produced foci that were indistinguishable from those produced by MV in vitro in a monkey kidney cell line (BGMK) that are permissive for wild type MV.
  • M063R expression was not required for myxoma virus binding, entry or early gene expression, whereas DNA replication was aborted and late genes were not expressed in vMyx63KO infected rabbit cells.
  • Finally, an in vivo pathogenesis study indicated that vMyx63KO failed to cause any signs of classic myxomatosis in infected rabbits, but functioned as a non-replicating vaccine and provided protection for subsequent challenge by wild type myxoma virus.
  • Altogether, these observations demonstrate that M063R plays a critical role in determining the host specificity of myxoma virus in rabbit cells.
  • [MeSH-major] Myxoma virus / physiology. Myxomatosis, Infectious / virology. Open Reading Frames / physiology

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  • (PMID = 17184804.001).
  • [ISSN] 0042-6822
  • [Journal-full-title] Virology
  • [ISO-abbreviation] Virology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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18. Gonzalez-Juanatey C, Regueiro-Abel M, Lopez-Agreda H, Peña-Martínez F, Gonzalez-Gay MA: Giant left atrial myxoma mimicking severe mitral valve stenosis. Int J Cardiol; 2008 Jul 21;127(3):e110-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant left atrial myxoma mimicking severe mitral valve stenosis.
  • We report a case of giant left atrial myxoma in a young patient with clinical manifestation as congestive heart failure attributable to severe mitral valve stenosis.
  • An early clinical and echocardiographic diagnosis was performed and the patient had an optimal outcome with surgery treatment.
  • [MeSH-major] Heart Neoplasms / ultrasonography. Mitral Valve Stenosis / ultrasonography. Myxoma / ultrasonography
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Heart Atria / ultrasonography. Humans

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  • (PMID = 17683811.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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19. Riad MG, Parks JD, Murphy PB, Thangathurai D: Infected atrial myxoma presenting with septic shock. J Cardiothorac Vasc Anesth; 2005 Aug;19(4):508-11
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  • [Title] Infected atrial myxoma presenting with septic shock.
  • [MeSH-major] Heart Atria. Heart Neoplasms / complications. Myxoma / complications. Shock, Septic / etiology. Staphylococcal Infections / etiology
  • [MeSH-minor] Adult. Diagnosis, Differential. Echocardiography, Transesophageal. Humans. Male. Staphylococcus aureus / isolation & purification

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  • (PMID = 16085260.001).
  • [ISSN] 1053-0770
  • [Journal-full-title] Journal of cardiothoracic and vascular anesthesia
  • [ISO-abbreviation] J. Cardiothorac. Vasc. Anesth.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Sayin OA, Ugurlucan M, Cinar T, Surmen B, Dursun M, Akyol Y, Tireli E: Right ventricular myxoma causing right ventricular outflow tract obstruction. J Card Surg; 2007 May-Jun;22(3):227-9
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  • [Title] Right ventricular myxoma causing right ventricular outflow tract obstruction.
  • Cardiac myxomas are the most common neoplasms of the heart.
  • In this report we present a patient who had been treated for a right ventricular myxoma originating from the interventricular septum and leading to right ventricular outflow tract obstruction.
  • [MeSH-major] Heart Neoplasms / complications. Myxoma / complications. Ventricular Outflow Obstruction / surgery

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  • (PMID = 17488423.001).
  • [ISSN] 0886-0440
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Singaraju S, Wanjari SP, Parwani RN: Odontogenic myxoma of the maxilla: A report of a rare case and review of the literature. J Oral Maxillofac Pathol; 2010 Jan;14(1):19-23
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  • [Title] Odontogenic myxoma of the maxilla: A report of a rare case and review of the literature.
  • Odontogenic myxoma represents an uncommon benign neoplasm comprising of 3-6% of all odontogenic tumors.
  • This article presents a rare case of odontogenic myxoma occurring in the maxilla of a 7-year-old male patient with a brief review of the pathogenesis, clinical, radiological, histopathological, ultrastructural and immunohistochemical characteristics of odontogenic myxoma.

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  • (PMID = 21180454.001).
  • [ISSN] 1998-393X
  • [Journal-full-title] Journal of oral and maxillofacial pathology : JOMFP
  • [ISO-abbreviation] J Oral Maxillofac Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2995999
  • [Keywords] NOTNLM ; Odontogenic myxomas / fibromyxoma / odontogenic tumors
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22. Chockalingam A, Jaganathan V, Gnanavelu G, Dorairajan S, Chockalingam V: Severe left ventricular dysfunction in left atrial myxoma--report of 2 cases. Angiology; 2006 Jan-Feb;57(1):119-22
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  • [Title] Severe left ventricular dysfunction in left atrial myxoma--report of 2 cases.
  • We report 2 patients with left atrial (LA) myxoma with associated severe left ventricular (LV) dysfunction.
  • LA myxoma was diagnosed by transthoracic echocardiography, which also detected severe systolic dysfunction and LV dilatation.
  • Regional wall motion abnormality and thinning were absent.
  • Coronary angiograms also showed no occlusive disease, but distal ectasia was seen in 1 patient.
  • Cardiac function improved following surgery for myxoma in 1 patient.
  • LV dysfunction, thus far, has not been directly attributed to myxoma.
  • Coronary embolization leading to myocardial infarction and coexisting coronary atherosclerosis are the recognized methods by which LV dysfunction manifests in myxoma.
  • Our report suggests the possibility of reversible severe global LV dysfunction due to cardiodepressant effect of myxoma through as yet unclear mechanisms.
  • [MeSH-major] Heart Neoplasms / complications. Myxoma / complications. Ventricular Dysfunction, Left / etiology
  • [MeSH-minor] Adult. Cardiac Surgical Procedures. Coronary Angiography. Diagnosis, Differential. Disease Progression. Echocardiography, Transesophageal. Female. Follow-Up Studies. Heart Atria. Humans. Male. Middle Aged. Severity of Illness Index. Stroke Volume

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  • (PMID = 16444467.001).
  • [ISSN] 0003-3197
  • [Journal-full-title] Angiology
  • [ISO-abbreviation] Angiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Yin Z, Jones GN, Towns WH 2nd, Zhang X, Abel ED, Binkley PF, Jarjoura D, Kirschner LS: Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis. Circulation; 2008 Mar 18;117(11):1414-22
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  • Dysregulation of the protein kinase A system, caused by mutation of the protein kinase A regulatory subunit gene PRKAR1A, causes the inherited tumor syndrome Carney complex, which includes cardiac myxomas as one of its cardinal features.
  • These biochemical changes lead to myxoma-like changes, indicating that these mice may be a good model with which to study the formation of these tumors.
  • [MeSH-major] Cyclic AMP-Dependent Protein Kinase RIalpha Subunit / deficiency. Fetal Heart / pathology. Heart Neoplasms / genetics. Myxoma / genetics

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  • (PMID = 18316483.001).
  • [ISSN] 1524-4539
  • [Journal-full-title] Circulation
  • [ISO-abbreviation] Circulation
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA112268; United States / NCI NIH HHS / CA / CA16058; United States / NICHD NIH HHS / HD / HD01323
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / Prkar1a protein, mouse; 0 / Transcription Factors; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases; EC 2.7.7.- / Cre recombinase; EC 2.7.7.- / Integrases
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24. Arnaiz G P, Toledo G I, Borzutzky S A, Urcelay M G, Heusser R F, Garay G F, Castillo N E, Toro R L, Becker R P, Arretz V C, Córdova A S: [Cardiac tumors in children and adults: A Multicentric retrospective study]. Rev Med Chil; 2006 Sep;134(9):1135-45
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  • There are important clinical differences between children and adults in the behavior of these tumors.
  • AIM: To compare the behavior of primary and secondary cardiac tumors, from fetal age to adults.
  • In children the diagnosis was made by fetal, transthoracic or transesophageal echocardiography in 23.6% and 8% of cases, respectively.
  • Eighty five percent were primary (10 benign and 1 malignant) and 15%, secondary tumors.
  • Seventy six percent were primary (18 benign and 1 malignant) and 24% secondary tumors.
  • Fifty six percent were myxomas.
  • In adults, myxomas are the predominant cardiac tumors.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Chile / epidemiology. Echocardiography. Female. Fetal Heart / ultrasonography. Fibroma / epidemiology. Fibroma / ultrasonography. Follow-Up Studies. Humans. Infant. Infant, Newborn. Male. Middle Aged. Myxoma / epidemiology. Myxoma / ultrasonography. Pregnancy. Retrospective Studies. Ultrasonography, Prenatal

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  • (PMID = 17171215.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Multicenter Study
  • [Publication-country] Chile
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25. Meng BY, Wang T, Zhang Q, Ma C, Pan XL, Peng L: [Cardiac myxoma in children: report of three cases]. Zhongguo Dang Dai Er Ke Za Zhi; 2009 Jan;11(1):82
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  • [Title] [Cardiac myxoma in children: report of three cases].
  • [MeSH-major] Heart Neoplasms / diagnosis. Myxoma / diagnosis

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  • (PMID = 19149932.001).
  • [ISSN] 1008-8830
  • [Journal-full-title] Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
  • [ISO-abbreviation] Zhongguo Dang Dai Er Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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26. Sokolov IM, Volkova NS, Kuznetsova LI: [Myxoma of the left atrium: a case report]. Ter Arkh; 2007;79(9):69-70
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  • [Title] [Myxoma of the left atrium: a case report].
  • [MeSH-major] Heart Atria / pathology. Heart Neoplasms / pathology. Myxoma / pathology

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  • (PMID = 18038591.001).
  • [ISSN] 0040-3660
  • [Journal-full-title] Terapevticheskiĭ arkhiv
  • [ISO-abbreviation] Ter. Arkh.
  • [Language] rus
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Russia (Federation)
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27. Tondelli M, Mandrioli J, Ficarra G, Pentore R, Girolami F, Ghidoni I, Agnoletto V: Teaching NeuroImage: When right atrial myxoma meets patent foramen ovale: a case of paradoxical brain embolism. Neurology; 2008 Jan 1;70(1):e1-2
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  • [Title] Teaching NeuroImage: When right atrial myxoma meets patent foramen ovale: a case of paradoxical brain embolism.
  • [MeSH-major] Embolism, Paradoxical / etiology. Foramen Ovale, Patent / complications. Intracranial Embolism / etiology. Myxoma / complications

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  • (PMID = 18166698.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Jha NK, Khouri M, Murphy DM, Salustri A, Khan JA, Saleh MA, Von Canal F, Augustin N: Papillary fibroelastoma of the aortic valve--a case report and literature review. J Cardiothorac Surg; 2010;5:84
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  • The prevalence of primary cardiac tumour ranges from 0.0017-0.28% and papillary fibroelastoma is rare but not uncommon benign cardiac neoplasm.
  • The differential diagnosis considered was a thrombus, myxoma, Lambl's excrescence and infective vegetation.
  • Also, possibility of this diagnosis should be kept in mind while managing cardiac or valvular tumours.
  • [MeSH-major] Aortic Valve. Fibroma / diagnosis. Heart Neoplasms / diagnosis. Heart Valve Diseases / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • [ISSN] 1749-8090
  • [Journal-full-title] Journal of cardiothoracic surgery
  • [ISO-abbreviation] J Cardiothorac Surg
  • [Language] eng
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29. Wang F, Barrett JW, Ma Y, Dekaban GA, McFadden G: Induction of alpha/beta interferon by myxoma virus is selectively abrogated when primary mouse embryo fibroblasts become immortalized. J Virol; 2009 Jun;83(11):5928-32
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  • [Title] Induction of alpha/beta interferon by myxoma virus is selectively abrogated when primary mouse embryo fibroblasts become immortalized.
  • Here, we show that although primary MEFs are nonpermissive to myxoma virus replication, the corresponding immortalized MEFs support a highly productive myxoma virus infection.
  • We further demonstrate that this permissive phenotype for myxoma virus in immortalized MEFs is due to the immortalization-associated selective block to the cellular alpha/beta interferon induction machinery involved in responding to myxoma virus challenge.
  • [MeSH-major] Cell Separation / methods. Interferon-alpha / pharmacology. Interferon-beta / pharmacology. Myxoma virus / drug effects. Myxoma virus / physiology

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  • (PMID = 19297474.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Interferon-alpha; 0 / STAT1 Transcription Factor; 0 / Stat1 protein, mouse; 77238-31-4 / Interferon-beta
  • [Other-IDs] NLM/ PMC2681981
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30. Veras Filho Rde O, Pinheiro SS, Almeida IC, Arruda Mde L, Costa Ade L: Odontogenic myxoma of the maxilla invading the maxillary sinus. Braz J Otorhinolaryngol; 2008 Nov-Dec;74(6):945
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  • [Title] Odontogenic myxoma of the maxilla invading the maxillary sinus.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Myxoma / diagnosis. Odontogenic Tumors / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Maxillary Sinus / pathology. Neoplasm Invasiveness. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19582355.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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31. Bicer A, Turhan H, Cagrici G, Yasar AS, Sasmaz H: Asymptomatic left ventricular myxoma diagnosed incidentally by transthoracic echocardiography. Echocardiography; 2005 Nov;22(10):855-6
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  • [Title] Asymptomatic left ventricular myxoma diagnosed incidentally by transthoracic echocardiography.
  • [MeSH-major] Echocardiography / methods. Heart Neoplasms / diagnosis. Heart Ventricles / pathology. Myxoma / diagnosis. Ultrasonography, Interventional / methods
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging / methods. Myocardium / pathology. Rare Diseases

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  • (PMID = 16343171.001).
  • [ISSN] 0742-2822
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Jayasena SN, Ariyasinghe JT, Gunawardena DM, Gunawardena SA, de Silva MV: Large-cell calcifying sertoli cell tumour of the testis detected at screening of a family with Carney syndrome. Urol Int; 2005;75(4):365-7
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  • [Title] Large-cell calcifying sertoli cell tumour of the testis detected at screening of a family with Carney syndrome.
  • We report the detection of a large-cell calcifying Sertoli cell tumour (LCCSCT) in a 34-year-old male during screening of a family with Carney syndrome.
  • He also had a cardiac myxoma.
  • There is only one previous report of a malignant LCCSCT in a patient with Carney syndrome.
  • [MeSH-major] Calcinosis / pathology. Neoplasms, Multiple Primary / diagnosis. Sertoli Cell Tumor / pathology. Testicular Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Genetic Predisposition to Disease. Humans. Male. Middle Aged. Orchiectomy. Risk Factors

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  • (PMID = 16327308.001).
  • [ISSN] 0042-1138
  • [Journal-full-title] Urologia internationalis
  • [ISO-abbreviation] Urol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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33. Kumar S: Minimally invasive approach for surgical management of cardiac myxoma. Heart Lung Circ; 2006 Aug;15(4):280
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  • [Title] Minimally invasive approach for surgical management of cardiac myxoma.
  • [MeSH-major] Heart Neoplasms / surgery. Minimally Invasive Surgical Procedures / methods. Myxoma / surgery

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  • [CommentOn] Heart Lung Circ. 2006 Feb;15(1):38-43 [16473789.001]
  • (PMID = 16697703.001).
  • [ISSN] 1443-9506
  • [Journal-full-title] Heart, lung & circulation
  • [ISO-abbreviation] Heart Lung Circ
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Australia
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34. Khadilkar UN, Khadilkar NP, Rao PS, Chakravorty S, Goel G: Superficial angiomyxoma of the external ear not associated with Carney's complex: a case report. Kathmandu Univ Med J (KUMJ); 2007 Oct-Dec;5(4):546-9
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  • [Title] Superficial angiomyxoma of the external ear not associated with Carney's complex: a case report.
  • Superficial angiomyxomas are rare tumours and multiple tumours occurring in the external ear are invariably associated with Carney's complex.
  • In the present study, a solitary superficial angiomyxoma was found in a 20 year old lady; and there was no evidence of any of the components of Carney's complex at the time of presentation or at the end of 2 years of follow-up, after the surgical excision of the tumour.
  • [MeSH-major] Ear Neoplasms / diagnosis. Ear, External / pathology. Myxoma / diagnosis
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans

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  • (PMID = 18604093.001).
  • [ISSN] 1812-2078
  • [Journal-full-title] Kathmandu University medical journal (KUMJ)
  • [ISO-abbreviation] Kathmandu Univ Med J (KUMJ)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
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35. Matsukuma S, Yamaguchi H, Hamawaki M: Floating and entangled long right atrial thrombus mimicking myxoma. J Echocardiogr; 2010 Dec;8(4):146-7
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  • [Title] Floating and entangled long right atrial thrombus mimicking myxoma.

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  • [Cites] J Am Soc Echocardiogr. 1999 Jan;12 (1):64-9 [9882780.001]
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  • (PMID = 27278953.001).
  • [ISSN] 1349-0222
  • [Journal-full-title] Journal of echocardiography
  • [ISO-abbreviation] J Echocardiogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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36. Vandersteen A, Turnbull J, Jan W, Simpson J, Lucas S, Anderson D, Lin JP, Stratakis C, Pichert G, Lim M: Cutaneous signs are important in the diagnosis of the rare neoplasia syndrome Carney complex. Eur J Pediatr; 2009 Nov;168(11):1401-4
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  • [Title] Cutaneous signs are important in the diagnosis of the rare neoplasia syndrome Carney complex.
  • Histological examination confirmed multiple atrial myxomas.
  • The diagnosis of Carney complex was made clinically.
  • The patient was subsequently diagnosed with testicular seminomas and a cutaneous angiomyxoma.

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  • (PMID = 19219454.001).
  • [ISSN] 1432-1076
  • [Journal-full-title] European journal of pediatrics
  • [ISO-abbreviation] Eur. J. Pediatr.
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / Z01 HD000642; United States / Intramural NIH HHS / / ZIA HD000642-13; United States / NICHD NIH HHS / HD / Z01-HD-000642-04
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / Genetic Markers; 0 / PRKAR1A protein, human
  • [Other-IDs] NLM/ NIHMS307400; NLM/ PMC3138206
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37. Sowa S, Kleinrok A, Gburek T, Zaremba-Flis E: [Abscess of the mitral annulus mimicking left atrial tumour -- case report]. Kardiol Pol; 2007 May;65(5):571-4
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  • A case of a 50-year-old female with hypertension and diabetes, admitted to the hospital due to echocardiographically detected left atrial tumour, is presented.
  • Differential diagnosis included thrombus, myxoma and infectious tumour.
  • This report underlines the difficulties in the diagnosis of cardiac tumours.
  • [MeSH-major] Abscess / diagnosis. Heart Diseases / diagnosis
  • [MeSH-minor] Coronary Angiography. Diagnosis, Differential. Echocardiography. Female. Heart Atria / ultrasonography. Heart Neoplasms / diagnosis. Humans. Middle Aged. Mitral Valve / ultrasonography

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  • (PMID = 17577849.001).
  • [ISSN] 0022-9032
  • [Journal-full-title] Kardiologia polska
  • [ISO-abbreviation] Kardiol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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38. Nava Flores EL, Alvarez Blanco MA, Figueroa Vadillo J, Cruz Ortiz H: [Aggressive angiomyxoma of the vulva. Case report and literature review]. Ginecol Obstet Mex; 2009 Oct;77(10):487-90
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  • [Title] [Aggressive angiomyxoma of the vulva. Case report and literature review].
  • [Transliterated title] Angiomixoma agresivo de la vulva. Informe de un caso y revisión de la bibliografía.
  • Aggressive angiomyxoma is a rare vulvovaginal, perineal or pelvic mesenchymal neoplasm with a marked tendency to local recurrence but does not metastasize.
  • A case of an aggressive angiomyxoma of vulva in a 39-years-old women with an illness of one year prior to examination, with a slow and progressive growth of the left vulvar region, without other symptoms.
  • Hystopathology reported an aggressive angiomyxoma of the vulva, with tumor in resection margins.
  • Aggressive angiomyxoma is a rare neoplasm 150 cases has been reported.
  • [MeSH-major] Myxoma / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 19902678.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Mexico
  • [Number-of-references] 16
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39. Juneja MS, Arunkumar N, Srinivas CN, Rajan S, Ajit M: Right atrial myxoma arising from the inferior vena cava. Indian Heart J; 2006 Jul-Aug;58(4):356-8
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  • [Title] Right atrial myxoma arising from the inferior vena cava.
  • Histopathologic examination revealed the classic features of a myxoma.
  • This report is of a rare case of a cardiac myxoma arising from the inferior vena cava.
  • [MeSH-major] Heart Atria. Heart Neoplasms / pathology. Myxoma / pathology. Vena Cava, Inferior

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  • (PMID = 19039156.001).
  • [ISSN] 0019-4832
  • [Journal-full-title] Indian heart journal
  • [ISO-abbreviation] Indian Heart J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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40. Vasconcelos MC, Macedo LF: Multicavitated left atrial myxoma with dual coronary supply. Arq Bras Cardiol; 2008 Apr;90(4):e32
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  • [Title] Multicavitated left atrial myxoma with dual coronary supply.
  • [MeSH-major] Heart Neoplasms / blood supply. Myxoma / blood supply

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  • (PMID = 18516378.001).
  • [ISSN] 1678-4170
  • [Journal-full-title] Arquivos brasileiros de cardiologia
  • [ISO-abbreviation] Arq. Bras. Cardiol.
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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41. Herbst M, Wattjes MP, Urbach H, Inhetvin-Hutter C, Becker D, Klockgether T, Hartmann A: Cerebral embolism from left atrial myxoma leading to cerebral and retinal aneurysms: a case report. AJNR Am J Neuroradiol; 2005 Mar;26(3):666-9
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  • [Title] Cerebral embolism from left atrial myxoma leading to cerebral and retinal aneurysms: a case report.
  • Left atrial myxoma commonly leads to cerebral embolic ischemic stroke.
  • In addition to the formation of aneurysms in cerebral arteries, we report here the unique picture of a retinal involvement consisting in microaneurysm formation associated with myxomatous embolism.
  • [MeSH-major] Aneurysm / etiology. Heart Neoplasms / complications. Intracranial Aneurysm / etiology. Intracranial Embolism / etiology. Myxoma / complications. Retinal Vessels

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  • (PMID = 15760885.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Malik A, Singh KJ, Mehta A: Aggressive angiomyxoma of the spermatic cord: A rare entity. Indian J Urol; 2009 Jan;25(1):137-9
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  • [Title] Aggressive angiomyxoma of the spermatic cord: A rare entity.
  • Aggressive angiomyxoma (AA) is an uncommon tumor occurring in females and is rarely reported in males with propensity to recur.

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  • (PMID = 19468447.001).
  • [ISSN] 0970-1591
  • [Journal-full-title] Indian journal of urology : IJU : journal of the Urological Society of India
  • [ISO-abbreviation] Indian J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2684295
  • [Keywords] NOTNLM ; Angiomyxoma / immunohistochemistry and spermatic cord
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43. Michal M, Kazakov DV, Síma R, Vanecek T: Primitive small cell tumor with epithelial, gangliocytic, neuroendocrine, and mesenchymal differentiation: report of 2 cases. Int J Surg Pathol; 2007 Oct;15(4):429-36
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  • The mesenchymal areas appeared benign and could be likened to a fibroma having a densely collagenous stroma, or they had spindle cells set in the myxoid background, rendering a myxoma-like appearance.
  • We suggest the name "primitive small cell tumor with epithelial, gangliocytic, neuroendocrine, and mesenchymal differentiation" for this neoplasm.

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  • (PMID = 17913955.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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44. Jallad N, Parikh R, Daoko J, Albareqdar E, Al-Dehneh A, Goldstein J, Shamoon F, Connolly MW: Concurrent primary cardiac tumors of differing histology and origin: case report with literature review. Tex Heart Inst J; 2009;36(6):591-3
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  • Approximately 75% are benign, and nearly 50% of these are myxomas.
  • Herein, we report concurrent myxoma and papillary fibroelastoma, which tumors were found attached to the left atrial septum and aortic valve, respectively.

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  • (PMID = 20069087.001).
  • [ISSN] 1526-6702
  • [Journal-full-title] Texas Heart Institute journal
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
  • [Other-IDs] NLM/ PMC2801934
  • [Keywords] NOTNLM ; Echocardiography / fibroma / heart neoplasms/primary/diagnosis/surgery / myxoma / neoplasms, multiple primary/diagnosis/surgery
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45. Dragoumis K, Drevelengas A, Chatzigeorgiou K, Assimakopoulos E, Venizelos I, Togaridou E, Mikos T, Boulogianni G, Bontis J: Aggressive angiomyxoma of the vulva extending into the pelvis: report of two cases. J Obstet Gynaecol Res; 2005 Aug;31(4):310-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive angiomyxoma of the vulva extending into the pelvis: report of two cases.
  • Aggressive angiomyxoma is a rare soft-tissue neoplasm found mainly in the female pelvis.
  • We report our experience of a primary and a recurrent aggressive angiomyxoma.
  • [MeSH-major] Myxoma / diagnosis. Neoplasm Recurrence, Local / diagnosis. Pelvic Neoplasms / diagnosis. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Neoplasm Metastasis

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  • (PMID = 16018777.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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46. Dimassi A, Dimassi W, Arnaout MS: Giant right ventricular fibroma co-existing atrial septal defect in a 15 year old girl. Cardiol Young; 2009 Dec;19(6):630-2
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  • The most common benign cardiac tumours are the myxomas, the rhabdomyomas, and the fibromas, with the latter 2 variants being the most common tumours encountered in children.
  • [MeSH-minor] Adolescent. Contrast Media. Diagnosis, Differential. Echocardiography. Electrocardiography. Female. Humans. Magnetic Resonance Imaging

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  • (PMID = 19835654.001).
  • [ISSN] 1467-1107
  • [Journal-full-title] Cardiology in the young
  • [ISO-abbreviation] Cardiol Young
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media
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47. Butz T, Scholtz W, Körfer J, Maleszka A, Jategaonkar S, Meissner A, Trappe HJ, Körfer R, Horstkotte D, Kleikamp G, Faber L: Prolapsing left atrial myxoma: preoperative diagnosis using a multimodal imaging approach with magnetic resonance imaging and real-time three-dimensional echocardiography. Eur J Echocardiogr; 2008 May;9(3):430-2
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  • [Title] Prolapsing left atrial myxoma: preoperative diagnosis using a multimodal imaging approach with magnetic resonance imaging and real-time three-dimensional echocardiography.
  • We present the diagnostic work-up using a multimodal-imaging approach in a 74-year-old patient with a prolapsing tumour in the left atrium suggestive of a myxoma, causing severe congestive heart failure attributable to dynamic left ventricular inflow obstruction, and mimicking severe mitral valve stenosis.
  • Real-time three-dimensional echocardiography allowed to accurately image the entire volume of the myxoma, and to analyse the dynamic left ventricular inflow obstruction.
  • The mass was surgically removed, histology was diagnostic for myxoma, and the patient had an uneventful recovery.
  • Real-time three-dimensional echocardiography images the entire volume of a mass allowing for accurate measurements in multiple planes, and allowing for real-time evaluation of obstructive effects on ventricular in- or outflow.
  • [MeSH-major] Echocardiography, Three-Dimensional. Heart Neoplasms / diagnosis. Magnetic Resonance Imaging. Myxoma / diagnosis

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  • (PMID = 18490348.001).
  • [ISSN] 1532-2114
  • [Journal-full-title] European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology
  • [ISO-abbreviation] Eur J Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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48. Gajanayake I, Priestnall SL, Benigni L, English K, Summers BA, Garden OA: Paraneoplastic hypercalcemia in a dog with benign renal angiomyxoma. J Vet Diagn Invest; 2010 Sep;22(5):775-80
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  • [Title] Paraneoplastic hypercalcemia in a dog with benign renal angiomyxoma.
  • Immunohistochemical examination with vimentin, von Willebrand Factor, and alpha-smooth muscle actin confirmed the mass to be a renal angiomyxoma.
  • The present report describes a previously unreported renal neoplasm causing paraneoplastic hypercalcemia and highlights the possibility of paraneoplastic hypercalcemia being caused by a benign neoplasm.
  • [MeSH-major] Dog Diseases / diagnosis. Hypercalcemia / veterinary. Kidney Diseases / veterinary. Myxoma / veterinary

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  • (PMID = 20807942.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Tempe DK, Dutta D, Minhas H, Garg M, Virmani S: A rare case of myxoma in the right ventricular outflow tract extending to the pulmonary artery. Ann Card Anaesth; 2010 May-Aug;13(2):167-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of myxoma in the right ventricular outflow tract extending to the pulmonary artery.
  • [MeSH-major] Heart Neoplasms / ultrasonography. Myxoma / ultrasonography

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  • (PMID = 20442551.001).
  • [ISSN] 0974-5181
  • [Journal-full-title] Annals of cardiac anaesthesia
  • [ISO-abbreviation] Ann Card Anaesth
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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50. Hallward G, Valchanov K: An unexpected pre-operative diagnosis. Eur J Echocardiogr; 2010 Jan;11(1):89-90
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  • [Title] An unexpected pre-operative diagnosis.
  • This is a case report of a patient presenting with breathlessness who was thought to have suspected systemic lupus erythematosus, but was actually diagnosed with an atrial myxoma.
  • [MeSH-major] Heart Atria / pathology. Heart Neoplasms / ultrasonography. Myxoma / ultrasonography. Preoperative Care
  • [MeSH-minor] Adult. Diagnosis, Differential. Dyspnea. Echocardiography. Echocardiography, Transesophageal. Elective Surgical Procedures. Female. Humans. Incidental Findings. Lupus Erythematosus, Systemic. Mitral Valve Stenosis. Tachycardia, Sinus. Thoracic Surgery, Video-Assisted

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  • (PMID = 19939813.001).
  • [ISSN] 1532-2114
  • [Journal-full-title] European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology
  • [ISO-abbreviation] Eur J Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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51. Chen MA, Ahlgrim AA, Allen CT: Location, location, location: a left atrial mass. J Am Soc Echocardiogr; 2009 May;22(5):541.e3-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although initially thought to be a myxoma, the mass was pathologically proved to be a thrombus.
  • [MeSH-minor] Diagnosis, Differential. Heart Neoplasms / complications. Heart Neoplasms / ultrasonography. Humans. Male. Middle Aged

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  • (PMID = 19233615.001).
  • [ISSN] 1097-6795
  • [Journal-full-title] Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • [ISO-abbreviation] J Am Soc Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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52. Cunha CR, Santos PC, Steffen SP, Souza CB: [Right atrium myxoid chondrosarcoma]. Rev Bras Cir Cardiovasc; 2008 Jan-Mar;23(1):132-4
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  • We report a case of a 46 years-old woman, Caucasian, with hypertension and a primary diagnosis of infectious endocarditis.
  • A transthoracic echocardiogram was performed suggesting right atrium myxoma.
  • [MeSH-major] Chondrosarcoma / surgery. Heart Neoplasms / surgery. Myxoma / surgery

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  • (PMID = 18719842.001).
  • [Journal-full-title] Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular
  • [ISO-abbreviation] Rev Bras Cir Cardiovasc
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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53. Nishimoto K, Sumitomo M, Kakoi N, Asano T, Hayakawa M: Case of renal myxoma. Int J Urol; 2007 Mar;14(3):242-4
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  • [Title] Case of renal myxoma.
  • Renal myxomas are rare neoplasms.
  • Only three cases have been convincingly diagnosed as renal myxoma.
  • The microscopic examination showed the typical appearance of a myxoma, which consisted of large amounts of myxoid material containing a few uniformly scattered spindle cells The tumor cells showed immunoreactivity for vimentin but not for S-100 protein, epithelial membrane antigen, cytokeratin, alpha smooth muscle actin.
  • [MeSH-major] Kidney Neoplasms / diagnosis. Myxoma / diagnosis
  • [MeSH-minor] Adult. Angiography. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Nephrectomy. Tomography, X-Ray Computed

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  • (PMID = 17430264.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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54. McCluggage WG, Jamieson T, Dobbs SP, Grey A: Aggressive angiomyxoma of the vulva: Dramatic response to gonadotropin-releasing hormone agonist therapy. Gynecol Oncol; 2006 Mar;100(3):623-5
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  • [Title] Aggressive angiomyxoma of the vulva: Dramatic response to gonadotropin-releasing hormone agonist therapy.
  • BACKGROUND: Aggressive angiomyxoma (AA) is a vulvovaginal mesenchymal neoplasm with a marked tendency to local recurrence but which usually does not metastasise.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Gonadotropin-Releasing Hormone / agonists. Goserelin / therapeutic use. Myxoma / drug therapy. Vulvar Neoplasms / drug therapy

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  • (PMID = 16246403.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Receptors, Estrogen; 0F65R8P09N / Goserelin; 33515-09-2 / Gonadotropin-Releasing Hormone
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55. Kim MS, Park JH, Kang SK, Na MH, Lee JH, Choi SW, Jeong JO, Seong IW: Acute ST-segment elevation myocardial infarction due to a huge floating thrombus mimicking a myxoma in the left atrium. J Am Soc Echocardiogr; 2009 Sep;22(9):1085.e1-3
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  • [Title] Acute ST-segment elevation myocardial infarction due to a huge floating thrombus mimicking a myxoma in the left atrium.
  • The most common cause of the abrupt occlusion of a coronary artery is the rupture of a vulnerable atherosclerotic plaque.
  • The authors report a case of acute ST-segment elevation myocardial infarction caused by a huge left atrial thrombus mimicking a myxoma.
  • [MeSH-major] Heart Atria / ultrasonography. Heart Neoplasms / ultrasonography. Myocardial Infarction / ultrasonography. Myxoma / ultrasonography. Thrombosis / ultrasonography
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 19733794.001).
  • [ISSN] 1097-6795
  • [Journal-full-title] Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • [ISO-abbreviation] J Am Soc Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. Burke A, Li L, Kling E, Kutys R, Virmani R, Miettinen M: Cardiac inflammatory myofibroblastic tumor: a "benign" neoplasm that may result in syncope, myocardial infarction, and sudden death. Am J Surg Pathol; 2007 Jul;31(7):1115-22
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  • [Title] Cardiac inflammatory myofibroblastic tumor: a "benign" neoplasm that may result in syncope, myocardial infarction, and sudden death.
  • Cardiac tumors other than myxomas are rare.
  • Long-term follow-up in 2 patients demonstrated no evidence of disease or recurrence.
  • These cardiac myofibroblastic tumors are readily distinguished from other endocardial-based cardiac tumors, including papillary fibroelastoma and myxoma, which may present clinically in the same manner.


57. Colin P, Lagacé R, Caillaud JM, Sastre-Garau X, Klijanienko J: Fine-needle aspiration in myxofibrosarcoma: experience of Institut Curie. Diagn Cytopathol; 2010 May;38(5):343-6
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  • In an attempt to better define the representative cytologic criteria of MFS, we undertook a review and a reanalysis of a series of 14 cytology samples in 12 patients whose tumors were diagnosed as MFS.Using FNA technique and reviewing the original diagnoses, 11 cases were diagnosed as malignant and three as benign tumors.
  • The cytologic diagnosis of MFS was accurate in seven cases (2 primary tumors, 4 recurrences, and 1 metastasis).
  • Entities such as myxoid MFH, myxoid liposarcoma (MLP), myxoid DFSP, and myxoma should be considered in the differential diagnosis.
  • The cytological misdiagnosis is of limited clinical consequence because FNA findings suggestive of a myxoid tumor will be indicative for a surgical removal followed by the histopathological analysis.

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  • (PMID = 19899126.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Yang JJ, Xu JG, Li WY, Shen Y, Xu B, Shi QL: Hypertension in cardiopulmonary bypass: a sign of insufficient anticoagulation in a patient undergoing surgical resection of myxoma. Thromb Res; 2007;120(1):145-7
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  • [Title] Hypertension in cardiopulmonary bypass: a sign of insufficient anticoagulation in a patient undergoing surgical resection of myxoma.
  • [MeSH-major] Anticoagulants / therapeutic use. Hypertension / etiology. Myxoma / surgery. Thrombosis / complications. Thrombosis / drug therapy

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  • (PMID = 17030347.001).
  • [ISSN] 0049-3848
  • [Journal-full-title] Thrombosis research
  • [ISO-abbreviation] Thromb. Res.
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticoagulants
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59. Moyssakis I, Anastasiadis G, Papadopoulos D, Margos P, Votteas V: Second recurrence of cardiac myxoma in a young patient. A case report. Int J Cardiol; 2005 Jun 8;101(3):501-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Second recurrence of cardiac myxoma in a young patient. A case report.
  • Two cardiac myxomas, one in the right ventricle and another one in the right atrium causing pulmonary embolism, was removed in a 21-year-old male.
  • [MeSH-major] Heart Neoplasms / ultrasonography. Myxoma / ultrasonography. Neoplasm Recurrence, Local / ultrasonography

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  • (PMID = 15907424.001).
  • [ISSN] 0167-5273
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Ireland
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60. Kaya G, Augsburger E, Chavaz P, Saurat JH: CD44 and hyaluronate expression in follicular mucinosis. J Cutan Pathol; 2006 Mar;33(3):227-30
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  • Decrease of epidermal CD44 expression in patients of lichen sclerosus et atrophicus is potentially responsible for dermal deposition of HA in this disease.
  • Stromal HA accumulation is associated with decreased or lost expression of CD44 in perifollicular solitary cutaneous myxoma, myxoid dermatofibroma, and dermatofibrosarcoma protuberans.

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  • (PMID = 16466510.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers; 0 / Mucins; 9004-61-9 / Hyaluronic Acid
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61. Costa MJ, Makaryus AN, Rosman DR: A rare case of a cardiac papillary fibroelastoma of the pulmonary valve diagnosed by echocardiography. Int J Cardiovasc Imaging; 2006 Apr;22(2):199-203
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  • [Title] A rare case of a cardiac papillary fibroelastoma of the pulmonary valve diagnosed by echocardiography.
  • The majority of primary tumors of the heart are benign with papillary fibroelastomas being the third most common after myxomas and lipomas respectively.
  • Although benign, papillary fibroelastomas have the potential to cause turbulent flow, thrombus formation, and severe cerebral or coronary embolic disease.
  • We present a rare case of a papillary fibroelastoma occurring on the pulmonic valve.
  • [MeSH-minor] Aged. Diagnosis, Differential. Echocardiography, Transesophageal. Endocardial Fibroelastosis / diagnostic imaging. Endocardial Fibroelastosis / surgery. Humans. Male

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  • [Cites] Kyobu Geka. 2004 Mar;57(3):226-8 [15035080.001]
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  • (PMID = 16077998.001).
  • [ISSN] 1569-5794
  • [Journal-full-title] The international journal of cardiovascular imaging
  • [ISO-abbreviation] Int J Cardiovasc Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Khaspekov GL, Sheremet'eva GF, Skamrov AV, Nechaenko MA, Vinnitskiĭ LI, Vlasik TN, Goriunova LE, Rutkevich NM, Peklo MM, Bibilashvili RSh: [Phospholipase A2, group IIa, as an earlier unknown immunohistological marker of cardiac myxoma]. Arkh Patol; 2008 Mar-Apr;70(2):31-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Phospholipase A2, group IIa, as an earlier unknown immunohistological marker of cardiac myxoma].
  • Human cardiac myxoma exhibits highly positive phospholipase A2, group IIA, immunophenotype (100% positive cases).
  • [MeSH-major] Biomarkers, Tumor / metabolism. Group II Phospholipases A2 / metabolism. Heart Neoplasms / enzymology. Heart Neoplasms / pathology. Myxoma / enzymology. Myxoma / pathology

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  • (PMID = 18540439.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.1.1.4 / Group II Phospholipases A2; EC 3.1.1.4 / PLA2G2A protein, human
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63. Mabuchi T, Shimizu M, Ino H, Yamguchi M, Terai H, Fujino N, Nagata M, Sakata K, Inoue M, Yoneda T, Mabuchi H: PRKAR1A gene mutation in patients with cardiac myxoma. Int J Cardiol; 2005 Jul 10;102(2):273-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] PRKAR1A gene mutation in patients with cardiac myxoma.
  • The mutation of this gene causes Carney complex which is an autosomal dominant multiple neoplasia syndrome characterized by spotty pigmentations, endocrine overactivity and cardiac myxoma.
  • We hypothesized that cardiac myxoma may be associated with PRKAR1A gene mutation and determined whether mutation in the PRKAR1A gene is the cause of familial and sporadic cardiac myxoma.
  • METHODS: We studied seven patients (three males and four females) with cardiac myxoma.
  • Two of them had familial cardiac myxoma complicated with Carney complex.
  • The other five patients were characterized as sporadic cardiac myxomas.
  • A 16-year-old proband had a left atrial myxoma, pituitary adenoma and skin pigmentation.
  • His father also had left atrial myxoma and skin pigmentation.
  • In contrast, no mutations in the PRKAR1A gene were identified in the other five patients with sporadic cardiac myxomas.
  • CONCLUSIONS: These results suggest that mutation of the PRKAR1A gene may be associated with familial cardiac myxoma in Carney complex but may not be associated with sporadic cardiac myxoma.
  • [MeSH-major] DNA, Neoplasm / genetics. Heart Neoplasms / genetics. Mutation. Myxoma / genetics. Proteins / genetics

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  • (PMID = 15982496.001).
  • [ISSN] 0167-5273
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / DNA, Neoplasm; 0 / Genetic Markers; 0 / PRKAR1A protein, human; 0 / Proteins; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases
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64. Yamamoto K, Kondo A, Iwashita K, Umezawa Y, Ohta Y, Matsuyama T, Ozawa A, Ichikawa K, Miyasaka M, Inomoto C, Yasuda M: A case of superficial angiomyxoma. Tokai J Exp Clin Med; 2006 Jul;31(2):53-5
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  • [Title] A case of superficial angiomyxoma.
  • We report a case of a 19-year-old man who showed a brownish, elastic-soft, multilocular, pedunculated, solid tumor (10 × 6 × 6 cm), with scale crust and erosion, on the medial side of the right thigh.
  • The histopathology of a specimen removed completely revealed a tumor that was located between the middle layer of the dermis and the subcutaneous fatty tissue, was filled with a mucoid material, and was surrounded by a fibrous tissue.
  • Based on these clinical and histologic findings, we diagnosed the skin condition as superficial angiomyxoma.
  • [MeSH-major] Myxoma / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 21302222.001).
  • [ISSN] 2185-2243
  • [Journal-full-title] The Tokai journal of experimental and clinical medicine
  • [ISO-abbreviation] Tokai J. Exp. Clin. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vimentin
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65. Liapis A, Bakalianou K, Salakos N, Iavazzo C, Dalainas I, Kondi-Pafiti A: Vascular tumors: rare neoplasms of the female genital tract. Eur J Gynaecol Oncol; 2009;30(2):220-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • More specifically, we identified one patient with angiomyxoma, five patients with angiokeratoma, one patient with vascular malformation, two with cervical hemangioma, two with hemangioma of the uterus and two with ovarian hemangioma.
  • [MeSH-minor] Adult. Aged. Angiokeratoma / pathology. Female. Hemangioma / pathology. Humans. Middle Aged. Myxoma / pathology

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  • (PMID = 19480262.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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66. Endo M, Kawai A, Kobayashi E, Morimoto Y, Yamaguchi U, Nakatani F, Chuman H, Seki K, Beppu Y: Solitary intramuscular myxoma with monostotic fibrous dysplasia as a rare variant of Mazabraud's syndrome. Skeletal Radiol; 2007 Jun;36(6):523-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary intramuscular myxoma with monostotic fibrous dysplasia as a rare variant of Mazabraud's syndrome.
  • The rare coexistence of intramuscular myxoma (IM) and fibrous dysplasia (FD) is known as Mazabraud's syndrome.
  • We present an extremely rare combination of a solitary IM and monostotic FD as a variant of Mazabraud's syndrome, and discuss the importance of recognizing this rare coexistence for appropriate management of the patient.
  • [MeSH-major] Fibrous Dysplasia, Monostotic / diagnosis. Muscle Neoplasms / diagnosis. Myxoma / diagnosis
  • [MeSH-minor] Biopsy. Contrast Media. Diagnosis, Differential. Female. Gadolinium DTPA. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Radiopharmaceuticals. Syndrome. Technetium Tc 99m Medronate. Thigh. Tomography, Emission-Computed. Tomography, X-Ray Computed

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  • (PMID = 17139504.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Radiopharmaceuticals; K2I13DR72L / Gadolinium DTPA; X89XV46R07 / Technetium Tc 99m Medronate
  • [Number-of-references] 26
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67. Chinchurreta-Capote A, Trueba A, Hernández FJ, Piñas P, López S, Tena ME, Aznarez N, Portillo E, Castillón L: [Ocular findings in Carney complex]. Arch Soc Esp Oftalmol; 2006 Dec;81(12):709-11
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  • CASE REPORT: Carney complex (CNC) is a multiple neoplasia syndrome, inherited in an autosomal dominant manner, characterized by myxomas, spotty skin pigmentation, endocrine tumors and ophthalmic abnormalities.
  • DISCUSSION: We report the ocular findings which usually precede the most serious component of the complex, the cardiac myxoma.
  • [MeSH-major] Eyelid Neoplasms / pathology. Heart Neoplasms / pathology. Myxoma / pathology. Neoplastic Syndromes, Hereditary / pathology. Papilloma / pathology. Skin Neoplasms / pathology

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  • (PMID = 17199165.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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68. Washiyama N, Yamashita K, Terada H, Ohkura K, Akuzawa S: Surgical treatment of papillary fibroelastoma in the aortic valve: a case report. Ann Thorac Cardiovasc Surg; 2010 Aug;16(4):297-300
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  • With the exception of myxomas, primary tumors of the heart are very rare.

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  • (PMID = 21057452.001).
  • [ISSN] 2186-1005
  • [Journal-full-title] Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
  • [ISO-abbreviation] Ann Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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69. Alexiou K, Wilbring M, Matschke K: Angina pectoris as first manifestation of a huge biatrial myxoma. Acta Cardiol; 2009 Oct;64(5):667-8
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  • [Title] Angina pectoris as first manifestation of a huge biatrial myxoma.
  • The tumour mass was completely removed and histologic examination revealed a biatrial myxoma with extensive vascular lesions which apparently induced angina by coronary steal effect.
  • [MeSH-major] Angina Pectoris / etiology. Heart Neoplasms / complications. Myxoma / complications
  • [MeSH-minor] Aged. Cardiac Surgical Procedures / methods. Coronary Angiography. Diagnosis, Differential. Echocardiography, Transesophageal. Female. Follow-Up Studies. Heart Atria. Humans. Magnetic Resonance Imaging. Severity of Illness Index

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  • (PMID = 20058514.001).
  • [ISSN] 0001-5385
  • [Journal-full-title] Acta cardiologica
  • [ISO-abbreviation] Acta Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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70. Canales BK, Weiland D, Hoffman N, Slaton J, Tran M, Manivel JC, Monga M: Angiomyofibroblastoma-like tumors (cellular angiofibroma). Int J Urol; 2006 Feb;13(2):177-9
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  • We report two cases of this tumor in men arising as paratesticular masses of the scrotum, summarize the history of this tumor, and discuss why efforts should be made to differentiate it from aggressive angiomyxoma.

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  • (PMID = 16563146.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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71. Vistarini N, Alloni A, Aiello M, Viganò M: Minimally invasive video-assisted approach for left atrial myxoma resection. Interact Cardiovasc Thorac Surg; 2010 Jan;10(1):9-11
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  • [Title] Minimally invasive video-assisted approach for left atrial myxoma resection.
  • We report in the present study our ten-year experience with endoscopic cardiac surgery for left atrial myxoma resection.
  • Between January 1998 and January 2008, 14 patients (median age: 61 years) underwent surgery for left atrial myxoma resection at our institution.
  • Minimally invasive video-assisted surgery for left atrial myxoma resection is a safe, reproducible and cosmetic operation and can be considered an effective oncologic approach as an alternative to standard sternotomy.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Neoplasms / surgery. Myxoma / surgery. Thoracic Surgery, Video-Assisted

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  • (PMID = 19861325.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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72. Abu Hassan FO, Shomaf M: Intramuscular myxoma of the hypothenar muscles. Strategies Trauma Limb Reconstr; 2009 Oct;4(2):103-6
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  • [Title] Intramuscular myxoma of the hypothenar muscles.
  • Intramuscular myxomas of the hand are rare entities.
  • This article describes a case of hypothenar muscles myxoma treated with local surgical excision after frozen section biopsy with tumor-free margins.

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  • (PMID = 19690945.001).
  • [ISSN] 1828-8936
  • [Journal-full-title] Strategies in trauma and limb reconstruction (Online)
  • [ISO-abbreviation] Strategies Trauma Limb Reconstr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2746272
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73. Rathore KS, Hussenbocus S, Stuklis R, Edwards J: Novel strategies for recurrent cardiac myxoma. Ann Thorac Surg; 2008 Jun;85(6):2125-6
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  • [Title] Novel strategies for recurrent cardiac myxoma.
  • Histopathology confirmed them as myxomas.
  • He had a complete neurologic recovery, but presented 2 years later with recurrence of a cardiac myxoma in his left ventricle and left atrium.
  • [MeSH-major] Cryosurgery / instrumentation. Heart Neoplasms / surgery. Myxoma / surgery. Neoplasm Recurrence, Local / surgery. Thoracic Surgery, Video-Assisted / instrumentation

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  • (PMID = 18498840.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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74. Chen J, He Y, Li Z, Han J, Gu X, Wang L, Nixon JV: Myxoma of the left ventricular outflow tract. J Ultrasound Med; 2009 Nov;28(11):1585-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxoma of the left ventricular outflow tract.
  • [MeSH-major] Echocardiography / methods. Heart Neoplasms / etiology. Heart Neoplasms / ultrasonography. Myxoma / complications. Myxoma / ultrasonography. Ventricular Outflow Obstruction / etiology. Ventricular Outflow Obstruction / ultrasonography

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  • (PMID = 19854975.001).
  • [ISSN] 1550-9613
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Konstantinov IE, Saxena P, Barrett T, Jenkins G: Resection and reconstruction of the roof of the coronary sinus for an unusually attached left atrial myxoma. J Thorac Cardiovasc Surg; 2009 Apr;137(4):1032-4
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  • [Title] Resection and reconstruction of the roof of the coronary sinus for an unusually attached left atrial myxoma.
  • [MeSH-major] Cardiac Surgical Procedures / methods. Coronary Sinus / surgery. Heart Neoplasms / surgery. Myxoma / surgery

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  • (PMID = 19327539.001).
  • [ISSN] 1097-685X
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Al-Sarraf N, Al-Shammari F, Arafa O, Al-Fadhli J: Excision of a left atrial myxoma in the presence of a calcified ascending aorta: a surgical challenge. Gen Thorac Cardiovasc Surg; 2010 Feb;58(2):101-4
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  • [Title] Excision of a left atrial myxoma in the presence of a calcified ascending aorta: a surgical challenge.
  • Atrial myxomas are rare tumors that require surgical excision.
  • However, in the presence of a severely calcified ascending aorta, such excision becomes rather challenging and difficult.
  • Here we report a case of a left atrial myxoma in a 64-year-old woman with an extensively calcified aorta that was successfully excised using cardiopulmonary bypass beating-heart technique without the need for cardioplegic cardiac arrest and aortic cross-clamping.
  • [MeSH-major] Aortic Diseases / complications. Calcinosis / complications. Cardiac Surgical Procedures. Heart Neoplasms / surgery. Myxoma / surgery

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  • (PMID = 20155349.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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77. Ting SL, Koay CL, Ngo CT, Chieng LL, Chua CN: Orbital myxoma--an unusual cause of inferoorbital mass. Med J Malaysia; 2010 Sep;65(3):224-6
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  • [Title] Orbital myxoma--an unusual cause of inferoorbital mass.
  • RESULT: Histologically, the tumour was found to be an isolated orbital myxoma.
  • CONCLUSION: Isolated orbital myxoma is an exceedingly rare tumour of the orbit.
  • [MeSH-major] Myxoma / surgery. Orbital Neoplasms / surgery

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  • (PMID = 21939174.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Malaysia
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78. Johnston JB, Wang G, Barrett JW, Nazarian SH, Colwill K, Moran M, McFadden G: Myxoma virus M-T5 protects infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1. J Virol; 2005 Aug;79(16):10750-63
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  • [Title] Myxoma virus M-T5 protects infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1.
  • The myxoma virus (MV) M-T5 gene encodes an ankyrin repeat protein that is important for virus replication in cells from several species.
  • Insight was gained into the molecular mechanisms underlying the role of M-T5 as a host range determinant when the cell cycle regulatory protein cullin-1 (cul-1) was identified as a cellular binding partner of M-T5 and found to colocalize with the protein in both nuclear and cytosolic compartments.
  • [MeSH-major] Cell Cycle. Cell Cycle Proteins / physiology. Cullin Proteins / physiology. Myxoma virus / physiology. Viral Proteins / physiology

  • Gene Ontology. gene/protein/disease-specific - Gene Ontology annotations from this paper .
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  • (PMID = 16051867.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / Cullin 1; 0 / Cullin Proteins; 0 / M-T5 protein, Myxoma virus; 0 / Tumor Suppressor Proteins; 0 / Ubiquitin; 0 / Viral Proteins; 147604-94-2 / Cyclin-Dependent Kinase Inhibitor p27
  • [Other-IDs] NLM/ PMC1182661
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79. Scohy TV, Lecomte PV, McGhie J, Meijer R, Gommers D, Hofland J, Ten Cate FJ: Intraoperative real time three-dimensional transesophageal echocardiographic evaluation of right atrial tumor. Echocardiography; 2008 Jul;25(6):646-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Right atrial myxomas are uncommon heart tumors that can simulate nonspecific symptoms, such as fever, paroxysmal palpitations, chronic anemia, weight loss, and may escape timely diagnosis until the development of severe complications due to embolism.
  • This is the first case report of a right atrial myxoma visualized intraoperatively by RT3DTEE.

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  • (PMID = 18479357.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Fujii A, Inaoka M: [Huge left atrial myxoma masking the severity of mitral regurgitation; report of a case]. Kyobu Geka; 2008 May;61(5):410-3
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  • [Title] [Huge left atrial myxoma masking the severity of mitral regurgitation; report of a case].
  • It is well known that mobile or large left atrial myxoma may lead to valve obstruction and insufficiency, and affect transmitral valve flow.
  • A 50-year-old woman with a huge left atrial myxoma occluding the mitral valve was reported.
  • During the operation and after the myxoma resection, a severe mitral regurgitation, which was not observed during the preoperative echocardiogram, was noticed.
  • Our case suggests that careful evaluation of mitral valve during a myxoma resection operation is recommended.
  • [MeSH-major] Heart Neoplasms / complications. Mitral Valve / surgery. Mitral Valve Insufficiency / etiology. Mitral Valve Insufficiency / surgery. Myxoma / complications

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  • (PMID = 18464490.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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81. Li D, Song L, Fan Y, Li X, Li Y, Chen J, Zhu F, Guo C, Shi Y, Zhang L: Down-regulation of TIPE2 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Clin Immunol; 2009 Dec;133(3):422-7
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  • We examined the mRNA expression levels of TIPE2 and myxoma resistance protein (MX) 1 (one of type I interferon inducible genes) in peripheral blood mononuclear cells (PBMC) from 39 SLE patients and 35 healthy controls by real-time reverse transcription-polymerase chain reaction analysis (RT-PCR).
  • Furthermore, the TIPE2 mRNA expression levels negatively correlate with the SLE disease activity index (SLEDAI) (r=-0.5016, P=0.0011) and the MX1 mRNA expression levels (r=-0.8083, P<0.0001) in all the SLE patients.

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  • (PMID = 19748832.001).
  • [ISSN] 1521-7035
  • [Journal-full-title] Clinical immunology (Orlando, Fla.)
  • [ISO-abbreviation] Clin. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Intracellular Signaling Peptides and Proteins; 0 / Myxovirus Resistance Proteins; 0 / RNA, Messenger; EC 3.6.1.- / GTP-Binding Proteins
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82. Buric N, Jovanovic G, Pesic Z, Krasic D, Radovanovic Z, Mihailovic D, Tijanic M: Mandible schwannoma (neurilemmoma) presenting as periapical lesion. Dentomaxillofac Radiol; 2009 Mar;38(3):178-81
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  • Schwannoma is a benign nerve tumour that originates from Schwann cells, which cover peripheral nerves.
  • Radiographically, mandibular intraosseous schwannoma is difficult to differentiate from bone tumours such as ameloblastoma, myxoma, fibrous dysplasia, neurofibroma, central giant cell lesion or periapical lesion, so it should be included in the list of possible periapical pathoses.
  • [MeSH-minor] Diagnosis, Differential. Female. Follow-Up Studies. Humans. Immunohistochemistry. Molar / radiography. Radiography, Bitewing. S100 Proteins / analysis. Tooth Root / radiography. Tooth, Nonvital / radiography. Young Adult

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  • (PMID = 19225090.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / S100 Proteins
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83. De Marco A, La Tessa G, De Falco A, De Falco FA, Merola A, Sirabella G: Multiple cerebral aneurysms associated with atrial myxoma. A case report. Neuroradiol J; 2010 Mar;23(1):62-8
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  • [Title] Multiple cerebral aneurysms associated with atrial myxoma. A case report.
  • Cardiac myxoma is a tumor of mesenchymal origin accounting for half of all primary cardiac neoplasms.
  • Intracranial involvement by atrial myxoma is a rare cause of neurologic deficit.
  • When the myxoma arises in the left atrium, systemic emboli from a cardiac myxoma can lead to infarction, cerebral hemorrhage and aneurysm formation.
  • In the light of the potentially preventable nature of these lesions, the diagnosis of myxomatous aneurysms should be considered in any patient with neurologic symptoms and a history of cardiac myxoma.
  • We describe a case in which MR imaging and angiography were used to diagnose multiple cerebral aneurysms caused by left atrial myxoma.

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  • (PMID = 24148335.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Rodríguez-Vázquez M, García-Arpa M, Delgado M, Cortina P, Vera E, Romero G: [Superficial angiomyxoma]. Actas Dermosifiliogr; 2005 Jun;96(5):311-4
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  • [Title] [Superficial angiomyxoma].
  • [Transliterated title] Angiomixoma superficial.
  • Superficial angiomyxomas are clinically variable, infrequent, benign skin lesions.
  • An associated Carney's complex must always be ruled out with superficial angiomyxoma.
  • We present the case of a woman with a solitary, fast-growing superficial angiomyxoma.
  • [MeSH-major] Myxoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 16476394.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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85. Ergüneş K, Yetkin U, Yilik L, Tetik O, Lafçi B, Ozbek C, Yeşil M, Gürbüz A: Diagnosis and surgical treatment modalities in cardiac myxomas. Anadolu Kardiyol Derg; 2008 Oct;8(5):379-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnosis and surgical treatment modalities in cardiac myxomas.
  • [MeSH-major] Heart Neoplasms / diagnosis. Heart Neoplasms / surgery. Myxoma / diagnosis. Myxoma / surgery

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  • (PMID = 18849232.001).
  • [ISSN] 1308-0032
  • [Journal-full-title] Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • [ISO-abbreviation] Anadolu Kardiyol Derg
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] Turkey
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86. Arana-Arri E, de Vicuña Meléndez AG, Royo NL, Martín MC, Carbonero DR, Díez JB: A large atrial myxoma in a young woman. Intern Emerg Med; 2008 Dec;3(4):379-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A large atrial myxoma in a young woman.
  • [MeSH-major] Foramen Ovale, Patent / surgery. Heart Neoplasms / diagnosis. Myxoma / diagnosis

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  • [Cites] Radiographics. 2002 May-Jun;22(3):673-89 [12006696.001]
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  • [Language] eng
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87. Mirkinson LJ, Ratnayaka K, Sable CA, Gaskin PR: Carney complex presenting with Raynaud's phenomenon and erythematous macules of the extremities. Pediatr Cardiol; 2006 Mar-Apr;27(2):297-300
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  • Surgical excision and pathological examination of the mass confirmed the presence of a large, peduculated myxoma.
  • This case illustrates the presentation of Carney complex with left atrial myxoma as apparent vasculitis and Raynaud's phenomenon.
  • [MeSH-major] Heart Atria. Heart Neoplasms / complications. Myxoma / complications. Neoplastic Syndromes, Hereditary / complications. Raynaud Disease / etiology. Skin Diseases, Vascular / etiology

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  • (PMID = 16501880.001).
  • [ISSN] 0172-0643
  • [Journal-full-title] Pediatric cardiology
  • [ISO-abbreviation] Pediatr Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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88. Ozaydin M, Dogan A, Altinbas A: Left atrial myxoma presenting with acute myocardial infarction--a case report. Angiology; 2005 Nov-Dec;56(6):767-9
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  • [Title] Left atrial myxoma presenting with acute myocardial infarction--a case report.
  • Echocardiography and cardiac catheterization revealed a mass in the left atrium that was considered to be a myxoma.
  • Histopathologic examination confirmed the diagnosis of the myxoma.
  • Coronary embolism secondary to the myxoma was thought to be the cause of the MI.
  • [MeSH-major] Heart Neoplasms / complications. Myocardial Infarction / etiology. Myxoma / complications

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  • (PMID = 16327954.001).
  • [ISSN] 0003-3197
  • [Journal-full-title] Angiology
  • [ISO-abbreviation] Angiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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89. Josiah DT, Zhu D, Dreher F, Olson J, McFadden G, Caldas H: Adipose-derived stem cells as therapeutic delivery vehicles of an oncolytic virus for glioblastoma. Mol Ther; 2010 Feb;18(2):377-85
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We hypothesized that adipose-derived stem cells (ADSCs) possess the ability to home and deliver myxoma virus to glioma cells and experimental gliomas.
  • We infected ADSCs with vMyxgfp and found them to be permissive for myxoma virus replication.
  • We cocultured fluorescently labeled GBM cells with myxoma virus-infected ADSCs in three-dimensional assay and observed successful cross infection and concomitant cell death almost exclusively in GBM cells.
  • In vivo orthotopic studies injected with vMyxgfp-ADSCs intracranially away from the tumor demonstrated that myxoma virus was delivered by ADSCs resulting in significant survival increase.
  • Our data suggest that ADSCs are promising new carriers of oncolytic viruses, specifically myxoma virus, to brain tumors.
  • [MeSH-minor] Animals. Cell Line. Cell Line, Tumor. Female. Fluorometry. Humans. Magnetic Resonance Imaging. Mice. Mice, Nude. Myxoma virus / genetics. Myxoma virus / physiology. Oncolytic Virotherapy / methods

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  • (PMID = 19904233.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA012197; United States / NCI NIH HHS / CA / CA-12197
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2839314
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90. Imai Y, Taketani T, Maemura K, Takeda N, Harada T, Nojiri T, Kawanami D, Monzen K, Hayashi D, Murakawa Y, Ohno M, Hirata Y, Yamazaki T, Takamoto S, Nagai R: Genetic analysis in a patient with recurrent cardiac myxoma and endocrinopathy. Circ J; 2005 Aug;69(8):994-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic analysis in a patient with recurrent cardiac myxoma and endocrinopathy.
  • A 60 year-old male was referred for treatment of a cardiac myxoma in the right atrium.
  • He had a past history of left atrial cardiac myxoma at age 49 and pituitary microadenoma related to acromegaly at age 55.
  • He did not have a family history of cardiac neoplasm or endocrinopathy.
  • The intracardiac tumor was resected and its pathology was compatible with myxoma.
  • A diagnosis of Carney complex (CNC) was made because the diagnostic criteria of this neoplastic syndrome were satisfied by the presence of recurrent cardiac myxoma, endocrine tumor and spotty skin pigmentation.
  • Although it is the most common, usually benign, cardiac tumor, myxoma can cause a critical clinical situation and thus detecting the PRKAR1A mutation can assist with prognosis.
  • [MeSH-major] Endocrine Gland Neoplasms / genetics. Heart Neoplasms / genetics. Mutation. Myxoma / genetics. Proteins / genetics
  • [MeSH-minor] Acromegaly / complications. Acromegaly / diagnosis. Acromegaly / genetics. Cyclic AMP-Dependent Protein Kinase RIalpha Subunit. Cyclic AMP-Dependent Protein Kinases. Humans. Male. Middle Aged

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  • (PMID = 16041174.001).
  • [ISSN] 1346-9843
  • [Journal-full-title] Circulation journal : official journal of the Japanese Circulation Society
  • [ISO-abbreviation] Circ. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / PRKAR1A protein, human; 0 / Proteins; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases
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91. Zahedi RG, Wald DS, Ohri S: Carney complex. Ann Thorac Surg; 2006 Jul;82(1):320-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report an illustrated case of a 61-year-old woman with multiple atrial myxomas and cutaneous hyperpigmentation as part of the Carney complex.
  • The case is notable for an unusually late presentation in life and a strong family history of atrial myxomas and sudden death.
  • [MeSH-major] Cyclic AMP-Dependent Protein Kinases / genetics. Heart Neoplasms / genetics. Hyperpigmentation / genetics. Myxoma / genetics. Neoplasms, Multiple Primary / genetics. Neoplastic Syndromes, Hereditary / genetics

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  • (PMID = 16798242.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / PRKAR1A protein, human; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases
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92. Carlson JA, Chen KR: Cutaneous pseudovasculitis. Am J Dermatopathol; 2007 Feb;29(1):44-55
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  • Cyanotic-infarctive pseudovasculitis is due vaso-occlusion by emboli, thrombi, or fibrointimal hyperplasia (endarteritis obliterans) and includes varied conditions such as purpura fulminans, Coumadin necrosis, antiphospholipid antibody syndrome, cardiac myxoma, cholesterol embolization, calciphylaxis, and radiation arteritis.
  • Delayed and inappropriate diagnosis of pseudovasculitis leads to incorrect management and exposure to potentially deleterious treatment modalities such as corticosteroids and cytotoxic agents.
  • The diagnosis of a pseudovasculitic disorder requires a high index of suspicion and should always be part of the differential diagnosis of vasculitis.
  • Skin biopsy is a crucial step in differentiating pseudovasculitis from authentic vasculitis; absence of histologic evidence of vasculitis, particularly after multiple biopsies, should direct evaluation and diagnosis towards pseudovasculitis.
  • [MeSH-major] Skin / blood supply. Skin Diseases, Vascular / diagnosis. Vasculitis / diagnosis
  • [MeSH-minor] Blood Vessels / pathology. Diagnosis, Differential. Embolism / diagnosis. Embolism / pathology. Hemorrhage / diagnosis. Hemorrhage / pathology. Humans. Skin Diseases, Infectious / diagnosis. Skin Diseases, Infectious / pathology. Thrombosis / diagnosis. Thrombosis / pathology

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  • (PMID = 17284961.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 118
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93. Girish G, Jamadar DA, Landry D, Finlay K, Jacobson JA, Friedman L: Sonography of intramuscular myxomas: the bright rim and bright cap signs. J Ultrasound Med; 2006 Jul;25(7):865-9; quiz 870-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sonography of intramuscular myxomas: the bright rim and bright cap signs.
  • OBJECTIVE: The objective of this study was to retrospectively review sonographic images of pathologically proven soft tissue myxomas to determine whether a sonographic correlate to the bright rim and bright cap signs described in the magnetic resonance imaging literature is present.
  • METHODS: The study group consisted of 6 patients with pathologically proven soft tissue myxomas (1 man and 5 women; age range, 41-72 years; mean, 56.5 years).
  • Among other findings, images were also reviewed for a peripheral rim of increased echogenicity (termed the "bright rim sign") and for the presence of a triangular hyperechoic area adjacent to at least one of the poles of the mass (termed the "bright cap sign").
  • RESULTS: The bright rim and bright cap signs were seen in 5 (83%) of the 6 myxomas.
  • CONCLUSIONS: The sonographic bright rim and bright cap signs were associated with 5 (83%) of the 6 intramuscular myxomas.
  • Recognition of these features may assist in a more accurate sonographic diagnosis before biopsy.
  • [MeSH-major] Magnetic Resonance Imaging. Muscle Neoplasms / pathology. Muscle Neoplasms / ultrasonography. Myxoma / ultrasonography

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  • (PMID = 16798897.001).
  • [ISSN] 0278-4297
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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94. Rosetti M, Tighe DA, Chandok D, Gammie JS, Griffith BP, Folland ED: An unusual cause of pulmonary vein stenosis: a case report and review of the literature. Echocardiography; 2006 Sep;23(8):685-8
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  • We describe the case of a patient with the Carney syndrome and several resections for recurrent left atrial myxomas who underwent autotransplantation of the heart with resection of the left and right atria and reconstruction of both atria with bovine pericardium.
  • [MeSH-major] Cardiac Surgical Procedures / adverse effects. Hypertension, Pulmonary / etiology. Pulmonary Veno-Occlusive Disease / etiology
  • [MeSH-minor] Echocardiography, Doppler, Color. Echocardiography, Transesophageal. Female. Heart Atria / pathology. Heart Atria / surgery. Heart Neoplasms / surgery. Heart Transplantation. Humans. Middle Aged. Myxoma / surgery. Neoplasm Recurrence, Local / surgery. Reoperation. Thoracotomy. Transplantation, Autologous

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  • (PMID = 16970720.001).
  • [ISSN] 0742-2822
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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95. Quigley RL, Meursing DF, Rossman MI: Left atrial myxoma and mitral valve endocarditis--a cause and effect: a case report. Heart Surg Forum; 2006;9(1):E486-7
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  • [Title] Left atrial myxoma and mitral valve endocarditis--a cause and effect: a case report.
  • We report the case of a 55-year-old man who presented with an infected left atrial myxoma that seeded a normal native mitral valve.
  • [MeSH-major] Cardiac Surgical Procedures. Endocarditis / etiology. Endocarditis / microbiology. Heart Neoplasms / complications. Myxoma / complications

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  • (PMID = 16318932.001).
  • [ISSN] 1522-6662
  • [Journal-full-title] The heart surgery forum
  • [ISO-abbreviation] Heart Surg Forum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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96. Calé R, Andrade MJ, Lima S, Reis C, Ribeiras R, Ferreira MM, Gouveia R, Silva JA: Giant left atrial mass: thrombus mimicking myxoma. Rev Port Cardiol; 2008 Sep;27(9):1191-4
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  • [Title] Giant left atrial mass: thrombus mimicking myxoma.
  • [MeSH-major] Heart Atria. Heart Diseases / ultrasonography. Heart Neoplasms / ultrasonography. Myxoma / ultrasonography. Thrombosis / ultrasonography
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 19044180.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Portugal
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97. Cattadori IM, Albert R, Boag B: Variation in host susceptibility and infectiousness generated by co-infection: the myxoma-Trichostrongylus retortaeformis case in wild rabbits. J R Soc Interface; 2007 Oct 22;4(16):831-40
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  • [Title] Variation in host susceptibility and infectiousness generated by co-infection: the myxoma-Trichostrongylus retortaeformis case in wild rabbits.
  • We used a free-living rabbit population co-infected with the nematode Trichostrongylus retortaeformis, which appears to stimulate an acquired immune response, and the immunosuppressive poxvirus myxoma.
  • Modelling was used to examine how myxoma infection alters the immune-mediated establishment and death/expulsion of T. retortaeformis, and consequently affects parasite intensity and duration of the infection.
  • Our findings suggest that myxoma infections contribute to alter host susceptibility to the nematode, as co-infected rabbits showed higher worm intensity compared with virus negative hosts.
  • Results also suggest that myxoma disrupts the ability of the host to clear T. retortaeformis as worm intensities were consistently high and remained high in old rabbits.
  • We conclude that seasonal myxoma outbreaks enhance host susceptibility to the nematode and generate highly infected hosts that remain infectious for a longer time.

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  • (PMID = 17580288.001).
  • [ISSN] 1742-5689
  • [Journal-full-title] Journal of the Royal Society, Interface
  • [ISO-abbreviation] J R Soc Interface
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2386892
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98. Moore BA, Wine T, Burkey BB, Amedee RG, Butcher RB 2nd: Sphenoid sinus myxoma: case report and literature review. Ochsner J; 2008;8(4):166-71
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  • [Title] Sphenoid sinus myxoma: case report and literature review.
  • OBJECTIVES: We present the first known case in the English-language literature of a myxoma arising in the sphenoid sinus.
  • By describing the patient's clinical course and the salient features of this rare neoplasm, we seek to increase the awareness of the presentation, histological features, and treatment considerations for myxomas of the head and neck.
  • RESULTS: We describe the clinical course of a patient with a myxoma of the sphenoid sinus.
  • He remains without evidence of recurrent disease after 8 months.
  • CONCLUSIONS: Myxomas of the head and neck are rare neoplasms.

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  • (PMID = 21603497.001).
  • [ISSN] 1524-5012
  • [Journal-full-title] The Ochsner journal
  • [ISO-abbreviation] Ochsner J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3096368
  • [Keywords] NOTNLM ; Myxoma / neoplasms / sphenoid sinus
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99. Eiber M, Waldt S, Becker K, Rummeny E, Wörtler K: [Persistent knee pain and palpable tumor in the popliteal fossa]. Radiologe; 2009 Aug;49(8):748-52
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  • The case of a female Patient with increasing pain and a palpable mass in the right popliteal fossa shows the spectrum of possible differential diagnoses for the radiologist.
  • The diagnosis of a juxtaarticular myxoma made on the interpretation of conventional x-ray and magnetic resonance imaging was finally confirmed by biopsy.
  • [MeSH-major] Arthralgia / diagnosis. Arthralgia / etiology. Knee Joint / pathology. Myxoma / complications. Myxoma / diagnosis. Soft Tissue Neoplasms / complications. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Aged. Chronic Disease. Female. Humans. Palpation

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  • (PMID = 19225750.001).
  • [ISSN] 1432-2102
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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100. Sá MI, Abreu A, Cabral S, Reis AH, Torres S, de Oliveira F, Antunes M, Gomes JL: Myxoma in the right ventricular outlow tract. Rev Port Cardiol; 2007 Apr;26(4):377-81
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  • [Title] Myxoma in the right ventricular outlow tract.
  • We present a patient with dyspnea, cyanosis and presyncope during exercise related to intermittent obstruction of the right outflow tract by a myxoma of the right ventricle attached to the membranous interventricular septum by its pedicle.
  • Right ventricular myxomas are rare benign tumors and clinical manifestations depend mainly on size and site of attachment.
  • [MeSH-major] Heart Neoplasms. Heart Ventricles. Myxoma

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  • (PMID = 17695732.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Portugal
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