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1. Díaz Beveridge R, Richart Aznar P, Núñez Lozano C, Chirivella Casanova M, Corbellas Aparicio M, Montalar Salcedo J: Orbital and myocardial metastases of a primary pulmonary melanotic schwannoma. Clin Transl Oncol; 2010 Jul;12(7):509-11
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  • [Title] Orbital and myocardial metastases of a primary pulmonary melanotic schwannoma.
  • We present the case of a 60-year-old man with a primary pulmonary melanotic schwannoma treated with surgery and who developed an orbital and myocardial relapse 2 years after the initial diagnosis.
  • In more than half of cases, the Carney triad of myxomas of the heart, skin and breast, spotty pigmentation and endocrine hyperactivity is present.
  • A thorough pathological study is pivotal for a correct diagnosis.
  • The main differential diagnosis is with metastases of malignant melanoma.
  • Treatment should include radical surgery if possible; the role of chemotherapy and radiotherapy is uncertain due to the rarity of the tumour.

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  • (PMID = 20615829.001).
  • [ISSN] 1699-3055
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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2. Sayin OA, Ugurlucan M, Cinar T, Surmen B, Dursun M, Akyol Y, Tireli E: Right ventricular myxoma causing right ventricular outflow tract obstruction. J Card Surg; 2007 May-Jun;22(3):227-9
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  • [Title] Right ventricular myxoma causing right ventricular outflow tract obstruction.
  • Cardiac myxomas are the most common neoplasms of the heart.
  • In this report we present a patient who had been treated for a right ventricular myxoma originating from the interventricular septum and leading to right ventricular outflow tract obstruction.
  • [MeSH-major] Heart Neoplasms / complications. Myxoma / complications. Ventricular Outflow Obstruction / surgery

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  • (PMID = 17488423.001).
  • [ISSN] 0886-0440
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Chockalingam A, Jaganathan V, Gnanavelu G, Dorairajan S, Chockalingam V: Severe left ventricular dysfunction in left atrial myxoma--report of 2 cases. Angiology; 2006 Jan-Feb;57(1):119-22
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  • [Title] Severe left ventricular dysfunction in left atrial myxoma--report of 2 cases.
  • We report 2 patients with left atrial (LA) myxoma with associated severe left ventricular (LV) dysfunction.
  • LA myxoma was diagnosed by transthoracic echocardiography, which also detected severe systolic dysfunction and LV dilatation.
  • Regional wall motion abnormality and thinning were absent.
  • Coronary angiograms also showed no occlusive disease, but distal ectasia was seen in 1 patient.
  • Cardiac function improved following surgery for myxoma in 1 patient.
  • LV dysfunction, thus far, has not been directly attributed to myxoma.
  • Coronary embolization leading to myocardial infarction and coexisting coronary atherosclerosis are the recognized methods by which LV dysfunction manifests in myxoma.
  • Our report suggests the possibility of reversible severe global LV dysfunction due to cardiodepressant effect of myxoma through as yet unclear mechanisms.
  • [MeSH-major] Heart Neoplasms / complications. Myxoma / complications. Ventricular Dysfunction, Left / etiology
  • [MeSH-minor] Adult. Cardiac Surgical Procedures. Coronary Angiography. Diagnosis, Differential. Disease Progression. Echocardiography, Transesophageal. Female. Follow-Up Studies. Heart Atria. Humans. Male. Middle Aged. Severity of Illness Index. Stroke Volume

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  • (PMID = 16444467.001).
  • [ISSN] 0003-3197
  • [Journal-full-title] Angiology
  • [ISO-abbreviation] Angiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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4. Pan L, Peng L, Jean-Gilles J, Zhang X, Wieczorek R, Jain S, Levine V, Osman I, Prieto VG, Lee P: Novel PRKAR1A gene mutations in Carney Complex. Int J Clin Exp Pathol; 2010;3(5):545-8
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  • Carney complex is a syndrome that may include cardiac and mucocutaneous myxomas, spotting skin pigmentation, and endocrine lesions.
  • Here we present the case of a 57 year-old man with multiple skin lesions and cardiac myxomas.
  • Histology of the skin lesions showed lentigenous melanocytic hyperplasia and cutaneous myxomas, confirming the diagnosis of Carney complex.
  • This finding strengthens the argument that there are alternative ways in which the protein kinase A 1-alpha subunit plays a role in tumorigenesis.

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  • (PMID = 20606737.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / PRKAR1A protein, human
  • [Other-IDs] NLM/ PMC2897110
  • [Keywords] NOTNLM ; Carney complex / PRKAR1 / mutation / myxomas
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5. Hardy CM, Hinds LA, Kerr PJ, Lloyd ML, Redwood AJ, Shellam GR, Strive T: Biological control of vertebrate pests using virally vectored immunocontraception. J Reprod Immunol; 2006 Oct;71(2):102-11
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  • Laboratory experiments have shown that high levels of infertility can be induced in mice infected with recombinant murine cytomegalovirus and ectromelia virus expressing reproductive antigens as well as in rabbits using myxoma virus vectors.

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  • (PMID = 16870262.001).
  • [ISSN] 0165-0378
  • [Journal-full-title] Journal of reproductive immunology
  • [ISO-abbreviation] J. Reprod. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Viral Vaccines
  • [Number-of-references] 47
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6. Zerbo S, Argo A, Maresi E, Liotta R, Procaccianti P: Sudden death in adolescence caused by cardiac haemangioma. J Forensic Leg Med; 2009 Apr;16(3):156-8
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  • Cardiac myxoma is by far the most common tumor in adults, but in infants and adolescents the prevalent tumor of the heart is rhabdomyoma.
  • Among benign cardiac tumors, cardiac hemangiomas are rare and often diagnosed post-mortem due to the lack of specific clinical symptoms and signs.

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  • (PMID = 19239968.001).
  • [ISSN] 1878-7487
  • [Journal-full-title] Journal of forensic and legal medicine
  • [ISO-abbreviation] J Forensic Leg Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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7. Matsuoka H, Takata Y, Maeda S: Primary pulmonary myxoma. Ann Thorac Surg; 2005 Jan;79(1):329-30
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  • [Title] Primary pulmonary myxoma.
  • We report a case of a primary pulmonary myxoma.
  • Microscopic examination of the tumor disclosed elongated and stellate cells in a myxoid stroma, typical of myxoma.
  • [MeSH-major] Lung Neoplasms / surgery. Myxoma / surgery

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  • (PMID = 15620972.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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8. Russo MJ, Martens TP, Hong KN, Colman DL, Voleti VB, Smith CR Jr, Argenziano M: Minimally invasive versus standard approach for excision of atrial masses. Heart Surg Forum; 2007;10(1):E50-4
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  • Tissue diagnosis of the masses resected included myxoma (n = 24), fibroblastoma (n = 3), B-cell lymphoma (n = 1), and other benign masses (n = 6).

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  • (PMID = 17162403.001).
  • [ISSN] 1522-6662
  • [Journal-full-title] The heart surgery forum
  • [ISO-abbreviation] Heart Surg Forum
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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9. Zhang LW, Zhang MS, Zhang JT, Luo L, Xu ZL, Li GL, Wu Z, Wang ZC: [Myxoma of cranial base: study of 23 cases]. Zhonghua Yi Xue Za Zhi; 2006 Jun 20;86(23):1592-6
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  • [Title] [Myxoma of cranial base: study of 23 cases].
  • OBJECTIVE: To study the clinical manifestations and diagnosis and treatment of cranial base myxoma.
  • METHODS: The clinical data of 23 cases of myxoma of cranial base confirmed by pathology from Oct.
  • CONCLUSION: It is hard to remove the total myxoma of cranial base.
  • The important substance of the myxoma is mucus.
  • It is difficult to differentiate myxoma from chondrogenic tumor and chordoma in cranial base by the clinical and neuroradiological manifestations.
  • [MeSH-major] Myxoma / pathology. Myxoma / surgery. Skull Base Neoplasms / pathology. Skull Base Neoplasms / surgery

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  • (PMID = 16854295.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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10. Tsarpalis DC, Giannakopoulos CK, Lagadas AA, Toufexi EG: Aggressive angiomyxoma: case report and review of the literature. Eur J Gynaecol Oncol; 2007;28(6):480-2
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  • [Title] Aggressive angiomyxoma: case report and review of the literature.
  • Aggressive angiomyxoma is a rare benign mesenchymal neoplasm, found mainly in the female pelvis and perineum.
  • [MeSH-major] Genital Neoplasms, Female / diagnosis. Myxoma / diagnosis

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  • (PMID = 18179141.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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11. Mehmood F, Nanda NC, Vengala S, Winokur TS, Dod HS, Frans E, Patel V, Bodiwala K, Upendram S, Kirklin JK, McGiffin DC, Pacifico AD: Live three-dimensional transthoracic echocardiographic assessment of left atrial tumors. Echocardiography; 2005 Feb;22(2):137-43
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  • This preliminary study demonstrates the superiority of live three-dimensional transthoracic echocardiography (3D TTE) over two-dimensional (2D) TTE in the assessment of left atrial (LA) tumors in four patients studied by us (three myxomas, one hemangioma, all subsequently pathologically proven).
  • Because of the unique ability of live 3D TTE to systematically section and view the contents of an intracardiac mass, LA myxomas in the three patients studied could be more confidently diagnosed by noting isolated echolucent areas consistent with hemorrhage/necrosis in the tumor mass.
  • On the other hand, a definite echolucent area was found by 2D TTE in only two of the three patients with myxoma.
  • In the fourth patient with a hemangioma, live 3D TTE showed much more extensive and closely packed echolucencies with little solid tissue as compared to a myxoma consistent with a highly vascularized tumor.
  • In contrast, 2D TTE demonstrated only two isolated echolucencies in the tumor suggesting an erroneous diagnosis of myxoma.
  • [MeSH-minor] Female. Heart Atria. Hemangioma / ultrasonography. Humans. Male. Middle Aged. Myxoma / ultrasonography

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  • (PMID = 15693780.001).
  • [ISSN] 0742-2822
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Juneja MS, Arunkumar N, Srinivas CN, Rajan S, Ajit M: Right atrial myxoma arising from the inferior vena cava. Indian Heart J; 2006 Jul-Aug;58(4):356-8
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  • [Title] Right atrial myxoma arising from the inferior vena cava.
  • Histopathologic examination revealed the classic features of a myxoma.
  • This report is of a rare case of a cardiac myxoma arising from the inferior vena cava.
  • [MeSH-major] Heart Atria. Heart Neoplasms / pathology. Myxoma / pathology. Vena Cava, Inferior

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  • (PMID = 19039156.001).
  • [ISSN] 0019-4832
  • [Journal-full-title] Indian heart journal
  • [ISO-abbreviation] Indian Heart J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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13. Di Marco L, Pacini D, Leone A, Barbieri F, Lofiego C, Di Bartolomeo R: [Myxoma's grimaces]. G Ital Cardiol (Rome); 2008 Sep;9(9):641-2
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  • [Title] [Myxoma's grimaces].
  • [Transliterated title] Sberleffi da mixoma.
  • [MeSH-major] Heart Neoplasms / ultrasonography. Myxoma / ultrasonography

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  • (PMID = 18783085.001).
  • [ISSN] 1827-6806
  • [Journal-full-title] Giornale italiano di cardiologia (2006)
  • [ISO-abbreviation] G Ital Cardiol (Rome)
  • [Language] ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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14. Alexiou K, Wilbring M, Matschke K: Angina pectoris as first manifestation of a huge biatrial myxoma. Acta Cardiol; 2009 Oct;64(5):667-8
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  • [Title] Angina pectoris as first manifestation of a huge biatrial myxoma.
  • The tumour mass was completely removed and histologic examination revealed a biatrial myxoma with extensive vascular lesions which apparently induced angina by coronary steal effect.
  • [MeSH-major] Angina Pectoris / etiology. Heart Neoplasms / complications. Myxoma / complications
  • [MeSH-minor] Aged. Cardiac Surgical Procedures / methods. Coronary Angiography. Diagnosis, Differential. Echocardiography, Transesophageal. Female. Follow-Up Studies. Heart Atria. Humans. Magnetic Resonance Imaging. Severity of Illness Index

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  • (PMID = 20058514.001).
  • [ISSN] 0001-5385
  • [Journal-full-title] Acta cardiologica
  • [ISO-abbreviation] Acta Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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15. Carmo CR, Esteves PJ, Ferrand N, van der Loo W: Genetic variation at chemokine receptor CCR5 in leporids: alteration at the 2nd extracellular domain by gene conversion with CCR2 in Oryctolagus, but not in Sylvilagus and Lepus species. Immunogenetics; 2006 Jun;58(5-6):494-501
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  • Whereas in its natural host (Sylvilagus sps.) the effects of myxoma virus infections are benign, in European rabbit (Oryctolagus cuniculus), it causes a highly infectious disease with very high mortality rate, known as myxomatosis.
  • There is evidence that, as with HIV-1 virus in human, myxoma virus may use chemokine receptors such as CCR5 of the host target cell for entry and activation of pathways of immune avoidance.
  • The most striking was the replacement of a specific peptide motif of the second extracellular loop (ECL2) by a motif, which in other species characterizes the CCR2 molecules.

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  • (PMID = 16596402.001).
  • [ISSN] 0093-7711
  • [Journal-full-title] Immunogenetics
  • [ISO-abbreviation] Immunogenetics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CCR2 protein, human; 0 / Receptors, CCR2; 0 / Receptors, CCR5; 0 / Receptors, Chemokine
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16. Elbardissi AW, Dearani JA, Daly RC, Mullany CJ, Orszulak TA, Puga FJ, Schaff HV: Survival after resection of primary cardiac tumors: a 48-year experience. Circulation; 2008 Sep 30;118(14 Suppl):S7-15
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  • METHODS AND RESULTS: From 1957 to 2006, 323 consecutive patients underwent surgical resection of primary cardiac tumors; 163 (50%) with myxomas, 83 (26%) with papillary fibroelastomas, 18 (6%) with fibromas, 12 (4%) with lipomas, 28 (9%) with other benign primary cardiac tumors, and 19 (6%) with primary malignant tumors.
  • Univariate analysis indicated that patients who underwent resection of fibromas and myxomas had superior survival characteristics in comparison to the remainder of tumor variants; these results were consistent after adjusting for age at surgery, year of surgery, and cardiovascular risk factors.
  • Based on actuarial characteristics of the 2002 U.S. population, patients who underwent myxoma resection had survival characteristics that were not significantly different from that of an age and gender matched population (SMR 1.11, P=0.57) whereas those who underwent resection of fibromas (SMR 11.17, P=0.002), papillary fibroelastomas (SMR 3.17, P=0.0003), lipomas (SMR 5.0, P=0.0003), other benign tumors (SMR 4.63, P=0.003), and malignant tumors (SMR 101, P<0.0001) had significantly poorer survival characteristics.
  • The cumulative incidence of myxoma recurrence was 13% and occurred in a younger population (42 versus 57 years, P=0.003) with the risk of recurrence decreased after 4 years.
  • CONCLUSIONS: Surgical resection of primary cardiac tumors is associated with excellent long-term survival; patients with cardiac myxomas have survival characteristics that are not significantly different from that of a general population.
  • [MeSH-minor] Adult. Age Distribution. Aged. Cardiopulmonary Bypass. Female. Fibroma / mortality. Fibroma / surgery. Humans. Incidence. Kaplan-Meier Estimate. Lipoma / mortality. Lipoma / surgery. Male. Middle Aged. Multivariate Analysis. Myxoma / mortality. Myxoma / surgery. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / etiology. Proportional Hazards Models. Risk Assessment. Risk Factors. Severity of Illness Index. Sex Distribution. Time Factors

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  • (PMID = 18824772.001).
  • [ISSN] 1524-4539
  • [Journal-full-title] Circulation
  • [ISO-abbreviation] Circulation
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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17. Marchini JF, Rodrigues AJ, Schmidt A: A ventricular thrombus mimicking a tumour. BMJ Case Rep; 2009;2009
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  • These are usually associated with underlying heart disease, present in the left atrium or occupying aneurysms in the ventricular wall, usually the apex.
  • The case of a 33-year-old woman with a pedunculated cardiac mass not having these latter characteristics is reported.
  • Echocardiography revealed a mass emerging from the interventricular septum, and a myxoma was suspected.

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  • (PMID = 21886661.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028419
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18. Chikoteev SP, Shanturov VA, Andreeva NI, Gumerov RR: [Intermuscular myxoma of the pelvis]. Khirurgiia (Mosk); 2006;(11):63-4
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  • [Title] [Intermuscular myxoma of the pelvis].
  • [MeSH-major] Muscle, Skeletal / pathology. Myxoma / pathology. Pelvic Neoplasms / pathology

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  • (PMID = 17183775.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Russia (Federation)
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19. Quigley RL, Meursing DF, Rossman MI: Left atrial myxoma and mitral valve endocarditis--a cause and effect: a case report. Heart Surg Forum; 2006;9(1):E486-7
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  • [Title] Left atrial myxoma and mitral valve endocarditis--a cause and effect: a case report.
  • We report the case of a 55-year-old man who presented with an infected left atrial myxoma that seeded a normal native mitral valve.
  • [MeSH-major] Cardiac Surgical Procedures. Endocarditis / etiology. Endocarditis / microbiology. Heart Neoplasms / complications. Myxoma / complications

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  • (PMID = 16318932.001).
  • [ISSN] 1522-6662
  • [Journal-full-title] The heart surgery forum
  • [ISO-abbreviation] Heart Surg Forum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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20. Izgi A, Kirma C, Mansuroglu D, Tanalp AC, Zemheri E, Ipek G: Giant cystic left atrial myxoma as a cause of secondary pulmonary hypertension. Echocardiography; 2005 Jan;22(1):49-50
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  • [Title] Giant cystic left atrial myxoma as a cause of secondary pulmonary hypertension.
  • [MeSH-major] Heart Neoplasms / complications. Hypertension, Pulmonary / etiology. Myxoma / complications


21. Barlis P, Lim EJ, Gow PJ, Seevanayagam S, Calafiore P, Chan RK: Giant cardiac myxoma. Heart Lung Circ; 2007 Oct;16(5):389-91
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  • [Title] Giant cardiac myxoma.
  • Although cardiac myxomas remain an uncommon group of malignancies, they are the most common form of primary cardiac tumour.
  • We present a case of a 46-year-old man with chronic abdominal pain and discuss a number of diagnostic challenges that were confronted up until a definitive diagnosis of cardiac myxoma was made.
  • [MeSH-major] Heart Neoplasms / surgery. Heart Neoplasms / ultrasonography. Myxoma / surgery. Myxoma / ultrasonography

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  • (PMID = 17446132.001).
  • [ISSN] 1443-9506
  • [Journal-full-title] Heart, lung & circulation
  • [ISO-abbreviation] Heart Lung Circ
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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22. Tretina M, Hrdlicka M, Ondrásek J, Nĕmec P, Orban M: [Cardiac tumor in a pregnant patient]. Vnitr Lek; 2010 Jan;56(1):79-81
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  • Cardiac myxoma represents the most frequent cardiac tumor with a relatively low overall incidence.
  • With regard to high success of the surgical treatment, early diagnosis is crucial.
  • We present a case of cardiac myxoma in a pregnant woman, which was succesfully sugically removed.
  • [MeSH-major] Heart Neoplasms. Myxoma. Pregnancy Complications, Neoplastic

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  • (PMID = 20184116.001).
  • [ISSN] 0042-773X
  • [Journal-full-title] Vnitr̆ní lékar̆ství
  • [ISO-abbreviation] Vnitr Lek
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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23. Kríz J, Krepinská E, Tomsová M: [Angiomyxoma of the vulva--a case report]. Ceska Gynekol; 2007 Dec;72(6):423-5
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  • [Title] [Angiomyxoma of the vulva--a case report].
  • [Transliterated title] Angiomyxoma vulvae--kazuistika.
  • OBJECTIVE: The authors demonstrate the case of a rare vulvar angiomyxoma in a 57-year-old female.
  • SUBJECT AND METHOD: A rare case of pedunculated angiomyxoma involving the vulva of a 57-year-old female is reported.
  • CONCLUSION: Angiomyxoma is a rare locally infiltrative neoplasm of the vulvovaginal region, perineum and pelvis.

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  • (PMID = 18236902.001).
  • [ISSN] 1210-7832
  • [Journal-full-title] Ceska gynekologie
  • [ISO-abbreviation] Ceska Gynekol
  • [Language] CZE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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24. Misra S, Sinha PK, Koshy T, Sandhyamani S, Parija C, Gopal K: Accurate localization and echocardiographic-pathologic correlation of tricuspid valve angiolipoma by intraoperative transesophageal echocardiography. Echocardiography; 2009 Nov;26(10):1228-31
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  • Angiolipoma (angiolipohamartoma) of the tricuspid valve (TV) is a rare tumor which may be occasionally misdiagnosed as right atrial (RA) myxoma.
  • Correct diagnosis of RA tumors has therapeutic significance and guides management of patients, as myxomas are generally more aggressively managed than lipomas.
  • We describe a rare case of a pedunculated angiolipoma of the TV which was misdiagnosed as RA myxoma on TTE and discuss the echocardiographic-pathologic correlates of the tumor as well as its accurate localization by TEE.

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  • (PMID = 19725840.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Dawson D, Jin XY, Mitchell AR, Ormerod OO, Becher HH: Transthoracic diagnosis of left atrial appendage myxoma by real-time 3-dimensional echocardiography. J Am Soc Echocardiogr; 2005 Feb;18(2):192-3
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  • [Title] Transthoracic diagnosis of left atrial appendage myxoma by real-time 3-dimensional echocardiography.
  • [MeSH-major] Atrial Appendage. Computer Systems. Echocardiography, Three-Dimensional. Heart Neoplasms / ultrasonography. Myxoma / ultrasonography

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  • (PMID = 15682060.001).
  • [ISSN] 0894-7317
  • [Journal-full-title] Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • [ISO-abbreviation] J Am Soc Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Blackmon SH, Patel AR, Bruckner BA, Beyer EA, Rice DC, Vaporciyan AA, Wojciechowski Z, Correa AM, Reardon MJ: Cardiac autotransplantation for malignant or complex primary left-heart tumors. Tex Heart Inst J; 2008;35(3):296-300
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  • Malignant or complex benign tumors of the left heart can present a formidable challenge for complete resection, due to anatomic inaccessibility.
  • Cardiac autotransplantation (cardiac explantation, ex-vivo tumor resection, reconstruction, and reimplantation) was introduced for complex benign primary left-heart cardiac tumors by Cooley and for malignant left-heart tumors by Reardon.
  • Follow-up was complete in all patients.Of the 20 patients, 17 had malignant lesions, and 3 had benign disease.
  • Histology showed 7 malignant fibrous histiocytomas, 5 undifferentiated sarcomas, 3 leiomyosarcomas, 1 malignant osteosarcoma, 1 myxoid sarcoma, 2 paragangliomas, and 1 myxoma.
  • Fourteen patients had previous resection of their cardiac tumors, and 1 patient had repeat autotransplantation for recurrent disease.
  • All 3 patients with benign disease survived surgery and are alive without recurrent disease.
  • Local recurrence occurred in 3/18 patients with malignant disease: 1 underwent successful repeat autotransplantation and 2 are receiving chemotherapy.
  • The mean survival for all patients with sarcoma is 22 months.Cardiac autotransplantation enables complete resection and accurate reconstruction in many primary malignant and complex benign left-heart tumors.

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  • (PMID = 18941651.001).
  • [ISSN] 0730-2347
  • [Journal-full-title] Texas Heart Institute journal
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2565530
  • [Keywords] NOTNLM ; Heart neoplasms/mortality/surgery / heart transplantation/methods / replantation/methods / sarcoma/surgery / transplantation, autologous
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27. Stanford MM, McFadden G: Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer. Expert Opin Biol Ther; 2007 Sep;7(9):1415-25
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  • [Title] Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer.
  • In contrast, the poxvirus myxoma virus is a novel oncolytic candidate that has no history of use in humans directly, as it has a distinct and absolute host species tropism to lagomorphs (rabbits).
  • Myxoma virus has been recently shown to be able to also selectively infect and kill human tumor cells, a unique tropism that is linked to dysregulated intracellular signalling pathways found in the majority of human cancers.
  • This review outlines the existing knowledge on the tropism of myxoma virus for human cancer cells, as well as preclinical data exhibiting its ability to infect and clear tumors in animal models of cancer.
  • This is an exciting new therapeutic option for treating cancer, and myxoma virus joins a growing group of oncolytic virus candidates that are being developed as a new class of cancer therapies in man.
  • [MeSH-major] Myxoma virus / physiology. Neoplasms / therapy. Oncolytic Virotherapy

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  • (PMID = 17727330.001).
  • [ISSN] 1744-7682
  • [Journal-full-title] Expert opinion on biological therapy
  • [ISO-abbreviation] Expert Opin Biol Ther
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 102
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28. Zechini B, Cipriani P, Papadopoulou S, Di Nucci G, Petrucca A, Teggi A: Endocarditis caused by Lactococcus lactis subsp. lactis in a patient with atrial myxoma: a case report. Diagn Microbiol Infect Dis; 2006 Nov;56(3):325-8
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  • [Title] Endocarditis caused by Lactococcus lactis subsp. lactis in a patient with atrial myxoma: a case report.
  • We report a case of subacute endocarditis in a 55-year-old patient affected by left atrial myxoma and with a severe mitral regurgitation.
  • [MeSH-major] Endocarditis / microbiology. Lactococcus lactis / isolation & purification. Myxoma / surgery
  • [MeSH-minor] Bacterial Infections / complications. Bacterial Infections / therapy. Humans. Male. Middle Aged. Mitral Valve Insufficiency / diagnosis. Mitral Valve Insufficiency / etiology

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  • (PMID = 16757143.001).
  • [ISSN] 0732-8893
  • [Journal-full-title] Diagnostic microbiology and infectious disease
  • [ISO-abbreviation] Diagn. Microbiol. Infect. Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Amezcua CA, Begley SJ, Mata N, Felix JC, Ballard CA: Aggressive angiomyxoma of the female genital tract: a clinicopathologic and immunohistochemical study of 12 cases. Int J Gynecol Cancer; 2005 Jan-Feb;15(1):140-5
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  • [Title] Aggressive angiomyxoma of the female genital tract: a clinicopathologic and immunohistochemical study of 12 cases.
  • Aggressive angiomyxoma (AAM) is a distinctive neoplasm seen in the female genital tract.
  • [MeSH-major] Antigens, CD44 / analysis. Biomarkers, Tumor / analysis. Genital Neoplasms, Female / pathology. Myxoma / pathology

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  • (PMID = 15670309.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers, Tumor
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30. Li X, Schneider H, Peters A, Macaulay C, King E, Sun Y, Liu L, Dai E, Davids JA, McFadden G, Lucas A: Heparin alters viral serpin, serp-1, anti-thrombolytic activity to anti-thrombotic activity. Open Biochem J; 2008;2:6-15
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  • The secreted myxoma viral serpin, Serp-1 exerts profound anti-inflammatory activity in a wide range of animal models.
  • Heparin also facilitates the simultaneous thrombin-mediated cleavage of Serp-1 and prevents formation of a serpin-typical SDS-resistant complex, implying mutual neutralization of Serp-1 and thrombin.

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  • (PMID = 18949070.001).
  • [ISSN] 1874-091X
  • [Journal-full-title] The open biochemistry journal
  • [ISO-abbreviation] Open Biochem J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC2570549
  • [Keywords] NOTNLM ; GAGs / Serpin / heparin / myxoma virus / thrombin. / thrombosis
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31. Hidayat AA, Flint A, Marentette L, Torczynski E, Al-Qahtani JM, Ahl NC, Elner VM: Myxomas and angiomyxomas of the orbit: a clinicopathologic study of 6 cases. Ophthalmology; 2007 May;114(5):1012-9
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  • [Title] Myxomas and angiomyxomas of the orbit: a clinicopathologic study of 6 cases.
  • PURPOSE: To report clinical and histopathologic features and biologic behavior of orbital myxomas and angiomyxomas.
  • PARTICIPANTS: Patients with histopathologic diagnoses of orbital myxoma or angiomyxoma.
  • MAIN OUTCOME MEASURES: Final diagnosis, based on histopathology, special stains, and immunohistochemistry, and clinical course from analysis of metadata and clinical features.
  • RESULTS: Three myxomas and 3 angiomyxomas were identified in 5 males and 1 female.
  • Two angiomyxomas occurred in children ages 4 and 7 years whose tumors were locally aggressive and recurred.
  • Recurrence also complicated one case of myxoma after incomplete excision.
  • Small blood vessels were rare in myxomas but abundant in angiomyxomas.
  • CONCLUSIONS: Myxomas rarely involve orbital tissue, and no angiomyxomas of the region have been previously reported.
  • Angiomyxomas in children may be aggressive.
  • Tumor cell immunopositivity for vimentin, CD34, and factor XIIIa may assist in the histopathologic diagnosis.
  • [MeSH-major] Myxoma / pathology. Orbital Neoplasms / pathology

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  • (PMID = 17467533.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Vimentin; EC 2.3.2.13 / Factor XIIIa
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32. Simões O, Loureiro MJ, Miranda R, Lopes L, Almeida S, Cordeiro P, Cotrim C, Carrageta M: Left atrial myxoma associated with severe mitral regurgitation and patent foramen ovale. Rev Port Cardiol; 2007 Apr;26(4):447-9
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  • [Title] Left atrial myxoma associated with severe mitral regurgitation and patent foramen ovale.
  • [MeSH-major] Heart Atria. Heart Neoplasms / complications. Heart Septal Defects, Atrial / complications. Mitral Valve Insufficiency / complications. Myxoma / complications

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  • (PMID = 17695734.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Portugal
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33. Rodriguez FJ, Brown RD, Mohr JP, Piepgras DG, Thielen K, Blume RS, Connolly H, Petty G, Giannini C: Embolic atrial myxoma with neoplastic aneurysm formation and haemorrhage: a diagnostic challenge. Neuropathol Appl Neurobiol; 2006 Apr;32(2):213-6
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  • [Title] Embolic atrial myxoma with neoplastic aneurysm formation and haemorrhage: a diagnostic challenge.
  • [MeSH-major] Cerebral Hemorrhage / etiology. Heart Neoplasms / complications. Intracranial Aneurysm / etiology. Myxoma / complications. Neoplastic Cells, Circulating / pathology
  • [MeSH-minor] Adult. Bone Neoplasms / secondary. Brain / pathology. Diagnosis, Differential. Female. Heart Atria / pathology. Humans. Paresthesia / etiology. Vasculitis / pathology. Vision Disorders / etiology

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  • (PMID = 16599950.001).
  • [ISSN] 0305-1846
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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34. Vistarini N, Alloni A, Aiello M, Viganò M: Minimally invasive video-assisted approach for left atrial myxoma resection. Interact Cardiovasc Thorac Surg; 2010 Jan;10(1):9-11
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  • [Title] Minimally invasive video-assisted approach for left atrial myxoma resection.
  • We report in the present study our ten-year experience with endoscopic cardiac surgery for left atrial myxoma resection.
  • Between January 1998 and January 2008, 14 patients (median age: 61 years) underwent surgery for left atrial myxoma resection at our institution.
  • Minimally invasive video-assisted surgery for left atrial myxoma resection is a safe, reproducible and cosmetic operation and can be considered an effective oncologic approach as an alternative to standard sternotomy.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Neoplasms / surgery. Myxoma / surgery. Thoracic Surgery, Video-Assisted

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  • (PMID = 19861325.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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35. Chen JP: Myxoma: the intracardiac zebra. South Med J; 2008 Oct;101(10):986-7
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  • [Title] Myxoma: the intracardiac zebra.
  • [MeSH-major] Heart Neoplasms / complications. Myxoma / complications. Pulmonary Edema / etiology

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  • [CommentOn] South Med J. 2008 Oct;101(10):1035-7 [18791521.001]
  • (PMID = 18791532.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Comment; Editorial
  • [Publication-country] United States
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36. Hein W, Krönert H, Falk V, Wittekind C, Hasenfuss G: [A 17-year-old with cardiac mass and pulmonary embolism]. Internist (Berl); 2009 Dec;50(12):1408-14
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  • The transthoracic and transesophageal echocardiography showed a typical feature of myxoma as a cardiac mass in size of 3.3x3.6 cm in the right atrium attached to the atrial septum.
  • The myxoma specimens were histologically detected in the tumor mass as well as in the embolectomy material.
  • The detection of the right atrial myxoma as an uncommon feature of the pulmonary embolism emphasizes the importance of the early echocardiography in the diagnosis of pulmonary embolism.
  • [MeSH-major] Heart Neoplasms / complications. Heart Neoplasms / diagnostic imaging. Myxoma / complications. Myxoma / diagnostic imaging. Pulmonary Embolism / complications. Pulmonary Embolism / diagnostic imaging
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Ultrasonography. Young Adult

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  • [Cites] N Engl J Med. 2008 Dec 25;359(26):2804-13 [19109575.001]
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  • (PMID = 19727634.001).
  • [ISSN] 1432-1289
  • [Journal-full-title] Der Internist
  • [ISO-abbreviation] Internist (Berl)
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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37. Tzanakis NE, Giannopoulos GA, Efstathiou SP, Rallis GE, Nikiteas NI: Angiomyofibroblastoma of the spermatic cord: a case report. J Med Case Rep; 2010;4:79
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  • INTRODUCTION: Angiomyofibroblastoma is a benign soft tissue tumor with tendency to arise in the vulva.
  • CONCLUSION: This unusual neoplasm should be distinguished from aggressive angiomyxoma and other myxoid malignant tumors with widespread metastatic potential.

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  • [Cites] Am J Surg Pathol. 1992 Apr;16(4):373-82 [1314521.001]
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  • (PMID = 20202207.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2838917
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38. Piura B, Shaco-Levy R: Pedunculated aggressive angiomyxoma arising from the vaginal suburethral area: case report and review of literature. Eur J Gynaecol Oncol; 2005;26(5):568-71
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  • [Title] Pedunculated aggressive angiomyxoma arising from the vaginal suburethral area: case report and review of literature.
  • BACKGROUND: Aggressive angiomyxoma (AA) is an uncommon, slow growing, locally infiltrative but non-metastasizing, distinctive mesenchymal tumor that predominantly affects the pelvis and perineum of premenopausal women.
  • These findings are compatible with the diagnosis of AA.
  • CONCLUSIONS: AA is often clinically misdiagnosed and it is only the microscopic examination strengthened with immunohistochemical staining that definitely and undeniably contributes to the final diagnosis of AA.
  • [MeSH-major] Myxoma / diagnosis. Vaginal Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 16285583.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 22
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39. Rickelt S, Rizzo S, Doerflinger Y, Zentgraf H, Basso C, Gerosa G, Thiene G, Moll R, Franke WW: A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata. Mod Pathol; 2010 Nov;23(11):1429-37
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  • [Title] A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata.
  • Using novel antibodies of high avidity to--and specificity for--the constitutive desmosomal plaque protein, plakophilin-2 (Pkp2), in a systematic study of the molecular composition of junctions connecting the cells of soft tissue tumors, we have discovered with immunocytochemical, biochemical and electron microscopical methods, a novel type of adherens junctions in all 32 cardiac myxomata examined.
  • We have not detected Pkp2 in a series of noncardiac myxomata studied in parallel.
  • We propose to examine the marker value of Pkp2 in clinical diagnoses of cardiac myxomata and to develop Pkp2-targeted therapeutic reagents.
  • [MeSH-major] Adherens Junctions / chemistry. Biomarkers, Tumor / analysis. Heart Neoplasms / chemistry. Myxoma / chemistry. Plakophilins / analysis

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  • (PMID = 20693980.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ARVCF protein, human; 0 / Antigens, CD; 0 / Armadillo Domain Proteins; 0 / Biomarkers, Tumor; 0 / CDH2 protein, human; 0 / CTNNB1 protein, human; 0 / Cadherins; 0 / Cell Adhesion Molecules; 0 / Desmoplakins; 0 / JUP protein, human; 0 / PKP2 protein, human; 0 / PKP4 protein, human; 0 / Phosphoproteins; 0 / Plakophilins; 0 / alpha Catenin; 0 / beta Catenin; 156621-71-5 / osteoblast cadherin
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40. Ting SL, Koay CL, Ngo CT, Chieng LL, Chua CN: Orbital myxoma--an unusual cause of inferoorbital mass. Med J Malaysia; 2010 Sep;65(3):224-6
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  • [Title] Orbital myxoma--an unusual cause of inferoorbital mass.
  • RESULT: Histologically, the tumour was found to be an isolated orbital myxoma.
  • CONCLUSION: Isolated orbital myxoma is an exceedingly rare tumour of the orbit.
  • [MeSH-major] Myxoma / surgery. Orbital Neoplasms / surgery

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  • (PMID = 21939174.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Malaysia
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41. Igaz P, Rácz K, Szabolcs Z, Tulassay Z: [Clinical features and pathogenesis of Carney complex, a rare form of multiple endocrine neoplasia syndromes]. Orv Hetil; 2006 Mar 26;147(12):551-5
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  • Clinical features include spotty skin pigmentation, cutaneous and cardiac myxomas, multiple endocrine abnormalities and schwannomas.
  • The most characteristic endocrine abnormality is primary pigmented nodular adrenal hyperplasia that may result in clinically apparent Cushing's syndrome.
  • [MeSH-major] Cyclic AMP-Dependent Protein Kinases / genetics. Multiple Endocrine Neoplasia / diagnosis. Multiple Endocrine Neoplasia / genetics. Mutation
  • [MeSH-minor] Cyclic AMP-Dependent Protein Kinase RIalpha Subunit. Diagnosis, Differential. Endocrine System Diseases / diagnosis. Endocrine System Diseases / genetics. Female. Fibrous Dysplasia, Polyostotic / diagnosis. Fibrous Dysplasia, Polyostotic / genetics. Humans. Male. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / genetics. Neurofibromatosis 1 / diagnosis. Neurofibromatosis 1 / genetics. Peutz-Jeghers Syndrome / diagnosis. Peutz-Jeghers Syndrome / genetics. Pigmentation Disorders / diagnosis. Pigmentation Disorders / genetics

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  • (PMID = 16696379.001).
  • [ISSN] 0030-6002
  • [Journal-full-title] Orvosi hetilap
  • [ISO-abbreviation] Orv Hetil
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / PRKAR1A protein, human; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases
  • [Number-of-references] 24
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42. Germing A, Lindstaedt M, Mügge A, Laczkovics A, Fritz M: Severity of mitral regurgitation may be underestimated in the presence of a left atrial myxoma. J Heart Valve Dis; 2006 Nov;15(6):830-2
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  • [Title] Severity of mitral regurgitation may be underestimated in the presence of a left atrial myxoma.
  • It is well known that mobile or large left atrial myxoma may lead to valve obstruction and insufficiency, and affect transmitral valve flow.
  • The case is reported of a 47-year-old woman with severe mitral regurgitation (MR) and huge left atrial myxoma (6?4?3 cm).
  • Preoperatively, the MR appeared related to the myxoma and was classified as moderate.
  • Following extirpation of the myxoma, intraoperative transesophageal echocardiography (TEE) revealed a severe mitral regurgitant jet.
  • [MeSH-major] Diagnostic Errors / prevention & control. Heart Atria / ultrasonography. Heart Neoplasms / ultrasonography. Mitral Valve Insufficiency / classification. Mitral Valve Insufficiency / ultrasonography. Myxoma / ultrasonography
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Severity of Illness Index

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  • (PMID = 17152792.001).
  • [ISSN] 0966-8519
  • [Journal-full-title] The Journal of heart valve disease
  • [ISO-abbreviation] J. Heart Valve Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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43. Abu Hassan FO, Shomaf M: Intramuscular myxoma of the hypothenar muscles. Strategies Trauma Limb Reconstr; 2009 Oct;4(2):103-6
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  • [Title] Intramuscular myxoma of the hypothenar muscles.
  • Intramuscular myxomas of the hand are rare entities.
  • This article describes a case of hypothenar muscles myxoma treated with local surgical excision after frozen section biopsy with tumor-free margins.

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  • (PMID = 19690945.001).
  • [ISSN] 1828-8936
  • [Journal-full-title] Strategies in trauma and limb reconstruction (Online)
  • [ISO-abbreviation] Strategies Trauma Limb Reconstr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2746272
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44. Rathore KS, Hussenbocus S, Stuklis R, Edwards J: Novel strategies for recurrent cardiac myxoma. Ann Thorac Surg; 2008 Jun;85(6):2125-6
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  • [Title] Novel strategies for recurrent cardiac myxoma.
  • Histopathology confirmed them as myxomas.
  • He had a complete neurologic recovery, but presented 2 years later with recurrence of a cardiac myxoma in his left ventricle and left atrium.
  • [MeSH-major] Cryosurgery / instrumentation. Heart Neoplasms / surgery. Myxoma / surgery. Neoplasm Recurrence, Local / surgery. Thoracic Surgery, Video-Assisted / instrumentation

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  • (PMID = 18498840.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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45. Nishimoto K, Sumitomo M, Kakoi N, Asano T, Hayakawa M: Case of renal myxoma. Int J Urol; 2007 Mar;14(3):242-4
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  • [Title] Case of renal myxoma.
  • Renal myxomas are rare neoplasms.
  • Only three cases have been convincingly diagnosed as renal myxoma.
  • The microscopic examination showed the typical appearance of a myxoma, which consisted of large amounts of myxoid material containing a few uniformly scattered spindle cells The tumor cells showed immunoreactivity for vimentin but not for S-100 protein, epithelial membrane antigen, cytokeratin, alpha smooth muscle actin.
  • [MeSH-major] Kidney Neoplasms / diagnosis. Myxoma / diagnosis
  • [MeSH-minor] Adult. Angiography. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Nephrectomy. Tomography, X-Ray Computed

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  • (PMID = 17430264.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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46. Cappell MS, Lapin S, Rose M: Large right atrial myxoma containing gastric heterotopia presenting with dyspnea and bilateral leg edema due to pulmonary emboli and cardiovascular obstruction: the first known report of gastric heterotopia in the cardiovascular system. Dig Dis Sci; 2008 Feb;53(2):405-9
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  • [Title] Large right atrial myxoma containing gastric heterotopia presenting with dyspnea and bilateral leg edema due to pulmonary emboli and cardiovascular obstruction: the first known report of gastric heterotopia in the cardiovascular system.
  • A 52-year-old male presented with progressive dyspnea, bilateral leg edema, and elevated central venous pressure due to a large right atrial myxoma that caused vascular obstruction and pulmonary emboli.
  • The myxoma contained gastric heterotopia.
  • Other unusual features of this atrial myxoma included its large size, right atrial location, and attachment to the right atrial wall.
  • This report confirms and extends previous reports of glandular elements or enteric glands within atrial, or cardiac, myxomas.
  • The clinical presentation of the currently reported patient is explained as follows: the elevated central venous pressure resulted from cardiovascular obstruction and the dyspnea from multiple pulmonary emboli due to the large atrial myxoma.
  • The association of gastric heterotopia with atrial myxoma may, however, be clinically important because of the propensity of gastric heterotopia in the gastrointestinal tract to produce complications.
  • [MeSH-major] Heart Atria. Heart Neoplasms / pathology. Myxoma / pathology. Stomach

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  • (PMID = 17592776.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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47. Orlandi A, Ferlosio A, Angeloni C, Ciucci A, Giusto Spagnoli L: [Cardiac tumors]. Pathologica; 2005 Jun;97(3):115-23
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  • In the most recent classification, cardiac tumors are divided into benign (about 75% and malignant neoplasms in relationship to their tissue differentiation (rhabdomyoma, haemangioma, etc.) or uncertain aetiology (myxoma, papillary fibroelastoma).
  • The most frequent tumor is cardiac myxoma, which by itself represents about 50% of all primary cardiac neoplasms.
  • Although non-invasive technologies as trans-esophageal ecocardiography allow the detection and exact localization of cardiac mass, clinical diagnosis is often tardive.
  • This is due, besides the intrinsic rarity, to two main factors: first, the tumor is often asymptomatic (incidental autopic finding) or; alternatively, it may show aspecif symptoms mimicking heart failure or other pathologies.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Glomus Tumor / pathology. Hemangioma / pathology. Humans. Male. Middle Aged. Myxoma / genetics. Myxoma / pathology. Neoplasm Proteins / analysis. Papilloma / pathology. Pericytes / pathology. Rhabdomyoma / pathology. Sarcoma / chemistry. Sarcoma / pathology

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  • (PMID = 16259277.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
  • [Number-of-references] 29
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48. Bakir I, Van Vaerenbergh G, Deshpande R, Coddens J, Vanermen H: Right atrial tumor: a contraindication to minimally invasive surgery? Innovations (Phila); 2009 Jan;4(1):39-42
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  • In this article, we present our experience with a female patient, who had a right sided atrial tumor mimicking a myxoma.

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  • (PMID = 22436903.001).
  • [ISSN] 1556-9845
  • [Journal-full-title] Innovations (Philadelphia, Pa.)
  • [ISO-abbreviation] Innovations (Phila)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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49. Paul GK, Sen B, Bari MA, Hossain MA, Bari MS, Chanda SK, Siddique SR, Azam MG, Khan TA: A case report of right ventricular mass. Mymensingh Med J; 2010 Oct;19(4):614-7
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  • Myxomas originating in the right ventricles are even less common in paediatric patient.

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  • (PMID = 20956908.001).
  • [ISSN] 1022-4742
  • [Journal-full-title] Mymensingh medical journal : MMJ
  • [ISO-abbreviation] Mymensingh Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Bangladesh
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50. Cattadori IM, Albert R, Boag B: Variation in host susceptibility and infectiousness generated by co-infection: the myxoma-Trichostrongylus retortaeformis case in wild rabbits. J R Soc Interface; 2007 Oct 22;4(16):831-40
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  • [Title] Variation in host susceptibility and infectiousness generated by co-infection: the myxoma-Trichostrongylus retortaeformis case in wild rabbits.
  • We used a free-living rabbit population co-infected with the nematode Trichostrongylus retortaeformis, which appears to stimulate an acquired immune response, and the immunosuppressive poxvirus myxoma.
  • Modelling was used to examine how myxoma infection alters the immune-mediated establishment and death/expulsion of T. retortaeformis, and consequently affects parasite intensity and duration of the infection.
  • Our findings suggest that myxoma infections contribute to alter host susceptibility to the nematode, as co-infected rabbits showed higher worm intensity compared with virus negative hosts.
  • Results also suggest that myxoma disrupts the ability of the host to clear T. retortaeformis as worm intensities were consistently high and remained high in old rabbits.
  • We conclude that seasonal myxoma outbreaks enhance host susceptibility to the nematode and generate highly infected hosts that remain infectious for a longer time.

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  • (PMID = 17580288.001).
  • [ISSN] 1742-5689
  • [Journal-full-title] Journal of the Royal Society, Interface
  • [ISO-abbreviation] J R Soc Interface
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2386892
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51. Tawfik MA, Zyada MM: Odontogenic tumors in Dakahlia, Egypt: analysis of 82 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Feb;109(2):e67-73
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  • STUDY DESIGN: Records of the Oral and Maxillofacial Surgery and Oral Pathology Departments, Faculty of Dentistry, Mansoura University, with histologic diagnosis of odontogenic tumors (based on the World Health Organization classification, 2005), during a 15-year period, were analyzed.
  • Of these, (96.3%) were benign and (3.7%) were malignant.
  • Ameloblastoma (41.5%) was the most frequent type, followed by keratocystic odontogenic tumor (19.5%), odontoma (13.4%), and odontogenic myxoma (8.5%).

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 19969486.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Fujii A, Inaoka M: [Huge left atrial myxoma masking the severity of mitral regurgitation; report of a case]. Kyobu Geka; 2008 May;61(5):410-3
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  • [Title] [Huge left atrial myxoma masking the severity of mitral regurgitation; report of a case].
  • It is well known that mobile or large left atrial myxoma may lead to valve obstruction and insufficiency, and affect transmitral valve flow.
  • A 50-year-old woman with a huge left atrial myxoma occluding the mitral valve was reported.
  • During the operation and after the myxoma resection, a severe mitral regurgitation, which was not observed during the preoperative echocardiogram, was noticed.
  • Our case suggests that careful evaluation of mitral valve during a myxoma resection operation is recommended.
  • [MeSH-major] Heart Neoplasms / complications. Mitral Valve / surgery. Mitral Valve Insufficiency / etiology. Mitral Valve Insufficiency / surgery. Myxoma / complications

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  • (PMID = 18464490.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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53. Shahid N, Ahluwalia A, Sahasrabudhe N, Davenport A: Aggressive angiomyxoma of the vagina: a rare differential diagnosis of a lateral vaginal wall cyst. J Obstet Gynaecol; 2005 Aug;25(6):622-3
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  • [Title] Aggressive angiomyxoma of the vagina: a rare differential diagnosis of a lateral vaginal wall cyst.
  • [MeSH-major] Cysts / diagnosis. Myxoma / diagnosis. Vaginal Diseases / diagnosis. Vaginal Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 16234166.001).
  • [ISSN] 0144-3615
  • [Journal-full-title] Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
  • [ISO-abbreviation] J Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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54. Willems SM, Wiweger M, van Roggen JF, Hogendoorn PC: Running GAGs: myxoid matrix in tumor pathology revisited: what's in it for the pathologist? Virchows Arch; 2010 Feb;456(2):181-92
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  • Ever since Virchow introduced the entity myxoma, abundant myxoid extracellular matrix (ECM) has been recognized in various reactive and neoplastic lesions.
  • We discuss the possible role of the predominant constituents of the myxoid ECM and attempt to relate them to differences in clinical behavior.
  • [MeSH-minor] Fibrosarcoma / metabolism. Fibrosarcoma / pathology. Humans. Myxoma / metabolism. Myxoma / pathology

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  • (PMID = 19705152.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Glycosaminoglycans
  • [Number-of-references] 95
  • [Other-IDs] NLM/ PMC2828560
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55. Mabuchi T, Shimizu M, Ino H, Yamguchi M, Terai H, Fujino N, Nagata M, Sakata K, Inoue M, Yoneda T, Mabuchi H: PRKAR1A gene mutation in patients with cardiac myxoma. Int J Cardiol; 2005 Jul 10;102(2):273-7
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  • [Title] PRKAR1A gene mutation in patients with cardiac myxoma.
  • The mutation of this gene causes Carney complex which is an autosomal dominant multiple neoplasia syndrome characterized by spotty pigmentations, endocrine overactivity and cardiac myxoma.
  • We hypothesized that cardiac myxoma may be associated with PRKAR1A gene mutation and determined whether mutation in the PRKAR1A gene is the cause of familial and sporadic cardiac myxoma.
  • METHODS: We studied seven patients (three males and four females) with cardiac myxoma.
  • Two of them had familial cardiac myxoma complicated with Carney complex.
  • The other five patients were characterized as sporadic cardiac myxomas.
  • A 16-year-old proband had a left atrial myxoma, pituitary adenoma and skin pigmentation.
  • His father also had left atrial myxoma and skin pigmentation.
  • In contrast, no mutations in the PRKAR1A gene were identified in the other five patients with sporadic cardiac myxomas.
  • CONCLUSIONS: These results suggest that mutation of the PRKAR1A gene may be associated with familial cardiac myxoma in Carney complex but may not be associated with sporadic cardiac myxoma.
  • [MeSH-major] DNA, Neoplasm / genetics. Heart Neoplasms / genetics. Mutation. Myxoma / genetics. Proteins / genetics

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  • (PMID = 15982496.001).
  • [ISSN] 0167-5273
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / DNA, Neoplasm; 0 / Genetic Markers; 0 / PRKAR1A protein, human; 0 / Proteins; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases
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56. Plumb A, Shanks JH, Kochhar R: Development of aggressive angiomyxoma like tumour in a renal transplant. Clin Radiol; 2010 May;65(5):423-6
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  • [Title] Development of aggressive angiomyxoma like tumour in a renal transplant.
  • [MeSH-major] Kidney Neoplasms / radiography. Kidney Transplantation. Myxoma / radiography. Postoperative Complications / radiography


57. De Marco A, La Tessa G, De Falco A, De Falco FA, Merola A, Sirabella G: Multiple cerebral aneurysms associated with atrial myxoma. A case report. Neuroradiol J; 2010 Mar;23(1):62-8
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  • [Title] Multiple cerebral aneurysms associated with atrial myxoma. A case report.
  • Cardiac myxoma is a tumor of mesenchymal origin accounting for half of all primary cardiac neoplasms.
  • Intracranial involvement by atrial myxoma is a rare cause of neurologic deficit.
  • When the myxoma arises in the left atrium, systemic emboli from a cardiac myxoma can lead to infarction, cerebral hemorrhage and aneurysm formation.
  • In the light of the potentially preventable nature of these lesions, the diagnosis of myxomatous aneurysms should be considered in any patient with neurologic symptoms and a history of cardiac myxoma.
  • We describe a case in which MR imaging and angiography were used to diagnose multiple cerebral aneurysms caused by left atrial myxoma.

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  • (PMID = 24148335.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Reddy VK, Faulkner M, Bandarupalli N, Nanda NC, Singh P, Dutta R, Singh A, Pothineni KR, Dod HS, Bhardwaj R, Warden BE, Beto RJ, Jain AC: Incremental value of live/real time three-dimensional transthoracic echocardiography in the assessment of right ventricular masses. Echocardiography; 2009 May;26(5):598-609
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  • This case series demonstrates the incremental value of three-dimensional transthoracic echocardiography (3D TTE) over two-dimensional transthoracic echocardiography (2D TTE) in the assessment of 11 patients with right ventricular (RV) masses or mass-like lesions (three cases of RV thrombus, one myxoma, one fibroma, one lipoma, one chordoma, and one sarcoma and three cases of RV noncompaction, which are considered to be mass-like in nature).
  • Also, sectioning of cardiac tumors allowed more confidence in narrowing the differential diagnosis of the etiology of the mass.
  • RV noncompaction was also well studied, and the assessment with 3D TTE helped to give a more definitive diagnosis in these patients.

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  • (PMID = 19438700.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. Anwar AM, Nosir YF, Chamsi-Pasha MA, Ajam A, Chamsi-Pasha H: Right atrial metastasis mimicking myxoma in advanced hepatocellular carcinoma. Echocardiography; 2010 Jan;27(1):80-3
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  • [Title] Right atrial metastasis mimicking myxoma in advanced hepatocellular carcinoma.
  • We described two cases of advanced hepatocellular carcinoma with large masses in the right atrium mimicking atrial myxoma.
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans

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  • (PMID = 19765072.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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60. Liu J, Wennier S, Reinhard M, Roy E, MacNeill A, McFadden G: Myxoma virus expressing interleukin-15 fails to cause lethal myxomatosis in European rabbits. J Virol; 2009 Jun;83(11):5933-8
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  • [Title] Myxoma virus expressing interleukin-15 fails to cause lethal myxomatosis in European rabbits.
  • Myxoma virus (MYXV) is a poxvirus pathogenic only for European rabbits, but its permissiveness in human cancer cells gives it potential as an oncolytic virus.
  • [MeSH-major] Interleukin-15 / metabolism. Myxoma virus / metabolism. Myxomatosis, Infectious / pathology

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  • (PMID = 19279088.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Interleukin-15
  • [Other-IDs] NLM/ PMC2681933
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61. Yavari A, El-Mahy H, McWilliams ET: Right atrial mass in the context of recurrent non-Hodgkin's lymphoma: atrial myxoma presenting with atrial flutter. BMJ Case Rep; 2009;2009
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  • [Title] Right atrial mass in the context of recurrent non-Hodgkin's lymphoma: atrial myxoma presenting with atrial flutter.
  • A case is described of a 57-year-old man with a background of low-grade bronchus-associated lymphoid tissue (BALT) non-Hodgkin's lymphoma presenting with dyspnoea and palpitations.
  • Diagnostic work-up revealed paroxysmal atrial flutter and the presence of a mass in the right lower lobe at bronchoscopy, with histology confirming recurrent BALTOMA.
  • Transoesophageal echocardiography (TOE) confirmed the presence of a fleshy, mobile pedunculated right atrial mass adherent to the interatrial septum, with features more in keeping with an atrial myxoma rather than intracardiac lymphoma.
  • He proceeded to cardiotomy and excision of the mass with histology confirming an atrial myxoma.
  • The clinical and echocardiographic features of atrial myxomas and intracardiac lymphomas are briefly discussed.

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  • (PMID = 21686493.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3027868
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62. Devbhandari MP, Meraj S, Jones MT, Kadir I, Bridgewater B: Primary cardiac sarcoma: reports of two cases and a review of current literature. J Cardiothorac Surg; 2007;2:34
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  • We report the cases of two patients presenting with features of obstruction and embolism and a presumed diagnosis of left atrial myxoma.
  • Subsequent histology confirmed the diagnosis of sarcoma in both patients.
  • [MeSH-major] Heart Neoplasms / diagnosis. Heart Neoplasms / surgery. Sarcoma / diagnosis. Sarcoma / surgery

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  • (PMID = 17650338.001).
  • [ISSN] 1749-8090
  • [Journal-full-title] Journal of cardiothoracic surgery
  • [ISO-abbreviation] J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 12
  • [Other-IDs] NLM/ PMC1976316
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63. Imai Y, Taketani T, Maemura K, Takeda N, Harada T, Nojiri T, Kawanami D, Monzen K, Hayashi D, Murakawa Y, Ohno M, Hirata Y, Yamazaki T, Takamoto S, Nagai R: Genetic analysis in a patient with recurrent cardiac myxoma and endocrinopathy. Circ J; 2005 Aug;69(8):994-5
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  • [Title] Genetic analysis in a patient with recurrent cardiac myxoma and endocrinopathy.
  • A 60 year-old male was referred for treatment of a cardiac myxoma in the right atrium.
  • He had a past history of left atrial cardiac myxoma at age 49 and pituitary microadenoma related to acromegaly at age 55.
  • He did not have a family history of cardiac neoplasm or endocrinopathy.
  • The intracardiac tumor was resected and its pathology was compatible with myxoma.
  • A diagnosis of Carney complex (CNC) was made because the diagnostic criteria of this neoplastic syndrome were satisfied by the presence of recurrent cardiac myxoma, endocrine tumor and spotty skin pigmentation.
  • Although it is the most common, usually benign, cardiac tumor, myxoma can cause a critical clinical situation and thus detecting the PRKAR1A mutation can assist with prognosis.
  • [MeSH-major] Endocrine Gland Neoplasms / genetics. Heart Neoplasms / genetics. Mutation. Myxoma / genetics. Proteins / genetics
  • [MeSH-minor] Acromegaly / complications. Acromegaly / diagnosis. Acromegaly / genetics. Cyclic AMP-Dependent Protein Kinase RIalpha Subunit. Cyclic AMP-Dependent Protein Kinases. Humans. Male. Middle Aged

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  • (PMID = 16041174.001).
  • [ISSN] 1346-9843
  • [Journal-full-title] Circulation journal : official journal of the Japanese Circulation Society
  • [ISO-abbreviation] Circ. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / PRKAR1A protein, human; 0 / Proteins; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases
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64. Shao HZ, Xiao XJ, Zhu P, Qian YJ, Yuan HS: A mobile mass--a left atrial undifferentiated sarcoma mimicking myxoma: a case report. Chin Med J (Engl); 2008 Jul 20;121(14):1339-41
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  • [Title] A mobile mass--a left atrial undifferentiated sarcoma mimicking myxoma: a case report.
  • [MeSH-major] Heart Neoplasms / diagnosis. Myxoma / diagnosis. Sarcoma / diagnosis
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Echocardiography. Female. Heart Atria / ultrasonography. Humans. Immunohistochemistry. Vimentin / analysis

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  • (PMID = 18713559.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Vimentin
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65. Gomes CC, Oliveira Cda S, Castro WH, de Lacerda JC, Gomez RS: Clonal nature of odontogenic tumours. J Oral Pathol Med; 2009 Apr;38(4):397-400
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among the polyclonal cases, two were OKC, one CEOT and one odontogenic mixoma.
  • [MeSH-minor] Clone Cells. DNA Methylation. DNA, Neoplasm / analysis. Epigenesis, Genetic. Female. Humans

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  • (PMID = 19298504.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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66. Dove S, Remoué P, Valo I, Ybarlucea LR, Panel N, Fondrinier E: Unusual female pelvic tumour: aggressive angiomyxoma. Eur J Obstet Gynecol Reprod Biol; 2008 Mar;137(1):123-5
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  • [Title] Unusual female pelvic tumour: aggressive angiomyxoma.
  • [MeSH-major] Myxoma / diagnosis. Pelvic Neoplasms / diagnosis

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  • (PMID = 17267097.001).
  • [ISSN] 0301-2115
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Ireland
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67. Kocaturk H, Karaman A, Bayram E, Çolak MC, Yurtman V: Left atrial myxoma and concomitant atherosclerotic coronary artery disease. Eurasian J Med; 2009 Dec;41(3):202-4
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  • [Title] Left atrial myxoma and concomitant atherosclerotic coronary artery disease.
  • Here we describe the case of a 71-year-old female patient who was admitted to our department with acute coronary syndrome.
  • Trans-thoracic echocardiography evaluation to assess left ventricular functions incidentally detected a left atrial mass attached to the inter-atrial septum together with a left ventricular segmental wall motion abnormality due to acute anterior myocardial infarction.
  • Coronary angiography revealed diffuse coronary artery disease.

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  • (PMID = 25610104.001).
  • [ISSN] 1308-8734
  • [Journal-full-title] The Eurasian journal of medicine
  • [ISO-abbreviation] Eurasian J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Other-IDs] NLM/ PMC4261271
  • [Keywords] NOTNLM ; Acute coronary syndrome / Atherosclerotic coronary artery disease / Left atrial mass
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68. Ozaydin M, Dogan A, Altinbas A: Left atrial myxoma presenting with acute myocardial infarction--a case report. Angiology; 2005 Nov-Dec;56(6):767-9
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  • [Title] Left atrial myxoma presenting with acute myocardial infarction--a case report.
  • Echocardiography and cardiac catheterization revealed a mass in the left atrium that was considered to be a myxoma.
  • Histopathologic examination confirmed the diagnosis of the myxoma.
  • Coronary embolism secondary to the myxoma was thought to be the cause of the MI.
  • [MeSH-major] Heart Neoplasms / complications. Myocardial Infarction / etiology. Myxoma / complications

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  • (PMID = 16327954.001).
  • [ISSN] 0003-3197
  • [Journal-full-title] Angiology
  • [ISO-abbreviation] Angiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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69. Shiraishi I, Yamagishi M, Kato R, Okumura Y, Sato H, Tanaka T, Hamaoka K: A case in a child of giant left-atrial myxoma associated with recurrent high fever and myxoma cells expressing interleukin-6. Eur J Pediatr; 2006 May;165(5):346-7
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  • [Title] A case in a child of giant left-atrial myxoma associated with recurrent high fever and myxoma cells expressing interleukin-6.
  • [MeSH-major] Fever / etiology. Heart Atria / pathology. Heart Neoplasms / metabolism. Interleukin-6 / metabolism. Myxoma / metabolism

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  • [Cites] Cardiovasc Pathol. 2000 Jan-Feb;9(1):33-7 [10739905.001]
  • [Cites] Tex Heart Inst J. 2001;28(1):3-7 [11330738.001]
  • [Cites] Cardiovasc Pathol. 2003 Jul-Aug;12 (4):233-6 [12826294.001]
  • (PMID = 16468027.001).
  • [ISSN] 0340-6199
  • [Journal-full-title] European journal of pediatrics
  • [ISO-abbreviation] Eur. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Interleukin-6
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70. Alkatan H, Al-Arfaj K: Myxoma of the cornea. Ann Saudi Med; 2008 Jul-Aug;28(4):297-9
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  • [Title] Myxoma of the cornea.
  • [MeSH-major] Cornea / pathology. Corneal Diseases / pathology. Eye Neoplasms / pathology. Myxoma / pathology

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  • (PMID = 18596391.001).
  • [ISSN] 0256-4947
  • [Journal-full-title] Annals of Saudi medicine
  • [ISO-abbreviation] Ann Saudi Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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71. Low KB, Huang J, Lim CH: Clinics in diagnostic imaging (126). Right atrial myxoma. Singapore Med J; 2009 May;50(5):546-9; quiz 550
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  • [Title] Clinics in diagnostic imaging (126). Right atrial myxoma.
  • Echocardiogram and multidetector computed tomography of the heart showed a right atrial mass typical of an atrial myxoma.
  • The imaging features of atrial myxoma and other conditions presenting as a right-sided cardiac mass are discussed.
  • [MeSH-major] Heart Atria / surgery. Heart Neoplasms / surgery. Myxoma / surgery

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  • (PMID = 19495530.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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72. Kucukarslan N, Kirilmaz A, Ulusoy E, Baysan O, Yildirim V, Ozal E, Sahin MA, Tatar H: Eleven-year experience in diagnosis and surgical therapy of right atrial masses. J Card Surg; 2007 Jan-Feb;22(1):39-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eleven-year experience in diagnosis and surgical therapy of right atrial masses.
  • BACKGROUND: Tumors arising from the right atrium are quite rare, and require special care during differential diagnosis for their management.
  • The histopathological examination of the surgically removed specimen revealed a benign tumor in eight patients (73%), and a malignant process in three (23%).
  • In eight patients with a benign tumor, atrial myxoma was the leading cause in half of the cases.
  • CONCLUSIONS: Tumors of the right atrium are rarely seen, and necessitate a unique attention during the process of diagnosis and surgical treatment.
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / pathology. Carcinoma, Renal Cell / surgery. Female. Humans. Leiomyoma / diagnosis. Leiomyoma / pathology. Leiomyoma / surgery. Male. Medical Records. Middle Aged. Prognosis. Retrospective Studies. Turkey

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  • (PMID = 17239209.001).
  • [ISSN] 0886-0440
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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73. Butt FM, Chindia ML, Wakoli KA: Problems in diagnosing odontogenic myxoma: case report. East Afr Med J; 2007 Mar;84(3):141-5
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  • [Title] Problems in diagnosing odontogenic myxoma: case report.
  • Tumours and tumour-like growths arising from odontogenic tissues constitute a heterogenous group of lesions whose diagnosis can be particularly challenging on the part of both surgeons and pathologists.
  • A case is presented of a 12 year-old boy who was subjected to inappropriate primary management of a left mandibular mass, due apparently to inadequate consultation to establish an accurate diagnosis.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Myxoma / diagnosis. Odontogenic Tumors / diagnosis
  • [MeSH-minor] Burkitt Lymphoma / diagnosis. Child. Diagnosis, Differential. Granuloma, Pyogenic / diagnosis. Hemangioma, Capillary / diagnosis. Humans. Male

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  • (PMID = 17600984.001).
  • [ISSN] 0012-835X
  • [Journal-full-title] East African medical journal
  • [ISO-abbreviation] East Afr Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Kenya
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74. Pai CY, Nieh S, Lee JC, Lo CP, Lee HS: Aggressive angiomyxoma of supraclavicular fossa: a case report. Head Neck; 2008 Jun;30(6):821-4
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  • [Title] Aggressive angiomyxoma of supraclavicular fossa: a case report.
  • BACKGROUND: Aggressive angiomyxoma (AAM) is a rare myxoid mesenchymal tumor that occurs almost exclusively in the adult pelvic-perineal region and predominantly in females.
  • METHODS: The patient was referred for evaluation of a firm nonmovable mass of the supraclavicular fossa that had progressively enlarged within the previous year.
  • CONCLUSION: Accurate diagnosis and a definite surgical margin are crucial because AAM is locally aggressive and easily recurrent.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Myxoma / pathology
  • [MeSH-minor] Clavicle. Humans. Male. Middle Aged. Neoplasm Invasiveness

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  • (PMID = 18213718.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Buksa M, Gerc V, Dilic M, Loza V, Naser N, Sokolovic S, Hodzic E, Brdjanovic S, Kulic M: Clinical, echocardiographic and echophonocardiographic characteristics of the atrial myxomas in 22 years period. Med Arh; 2009;63(6):320-2
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  • [Title] Clinical, echocardiographic and echophonocardiographic characteristics of the atrial myxomas in 22 years period.
  • INTRODUCTION: Atrial myxomas are the most frequent benign tumors of the heart.
  • Left atrial myxomas are about 3-4 times more frequent then right.
  • AIM: Review of atrial myxomas diagnosed at the Clinic of Cardiology in 20 years period and analysis of clinical characteristics, transthoracic echocardiographic (TTE), transesophageal echocardiographic (TEE), and M-mod echophonographic findings.
  • RESULTS: We found 24 atrial myxomas: 19 (79.2%) in left and 5 (20.810%) in right atrium.
  • Echophonocardiographic recordings showed early diastolic tumor "plop" in 10 patients and unusual late diastolic tumor "plop" in one right atrial myxoma, which has not yet been described.
  • CONCLUSIONS: TTE is a reliable method in diagnosis of atrial myxomas, but not in all cases, while TEE has been found as always reliable.
  • Echophonocardiographic recording is useful for confirmation and understanding of auscultatory finding when applicable.
  • [MeSH-major] Heart Neoplasms / ultrasonography. Myxoma / ultrasonography

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  • (PMID = 20380110.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Bosnia and Herzegovina
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76. Girish G, Jamadar DA, Landry D, Finlay K, Jacobson JA, Friedman L: Sonography of intramuscular myxomas: the bright rim and bright cap signs. J Ultrasound Med; 2006 Jul;25(7):865-9; quiz 870-1
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  • [Title] Sonography of intramuscular myxomas: the bright rim and bright cap signs.
  • OBJECTIVE: The objective of this study was to retrospectively review sonographic images of pathologically proven soft tissue myxomas to determine whether a sonographic correlate to the bright rim and bright cap signs described in the magnetic resonance imaging literature is present.
  • METHODS: The study group consisted of 6 patients with pathologically proven soft tissue myxomas (1 man and 5 women; age range, 41-72 years; mean, 56.5 years).
  • Among other findings, images were also reviewed for a peripheral rim of increased echogenicity (termed the "bright rim sign") and for the presence of a triangular hyperechoic area adjacent to at least one of the poles of the mass (termed the "bright cap sign").
  • RESULTS: The bright rim and bright cap signs were seen in 5 (83%) of the 6 myxomas.
  • CONCLUSIONS: The sonographic bright rim and bright cap signs were associated with 5 (83%) of the 6 intramuscular myxomas.
  • Recognition of these features may assist in a more accurate sonographic diagnosis before biopsy.
  • [MeSH-major] Magnetic Resonance Imaging. Muscle Neoplasms / pathology. Muscle Neoplasms / ultrasonography. Myxoma / ultrasonography

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  • (PMID = 16798897.001).
  • [ISSN] 0278-4297
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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77. Karlof E, Salzberg SP, Anyanwu AC, Steinbock B, Filsoufi F: How fast does an atrial myxoma grow? Ann Thorac Surg; 2006 Oct;82(4):1510-2
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  • [Title] How fast does an atrial myxoma grow?
  • We describe the case of a 58-year-old man who underwent coronary artery bypass grafting with an unremarkable transesophageal echocardiogram.
  • Pathology showed a myxoma that measured 15 x 3 cm implying a growth rate of 1.36 x 0.3 cm/month.
  • [MeSH-major] Heart Neoplasms / pathology. Myxoma / pathology

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  • (PMID = 16996968.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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78. Sá MI, Abreu A, Cabral S, Reis AH, Torres S, de Oliveira F, Antunes M, Gomes JL: Myxoma in the right ventricular outlow tract. Rev Port Cardiol; 2007 Apr;26(4):377-81
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  • [Title] Myxoma in the right ventricular outlow tract.
  • We present a patient with dyspnea, cyanosis and presyncope during exercise related to intermittent obstruction of the right outflow tract by a myxoma of the right ventricle attached to the membranous interventricular septum by its pedicle.
  • Right ventricular myxomas are rare benign tumors and clinical manifestations depend mainly on size and site of attachment.
  • [MeSH-major] Heart Neoplasms. Heart Ventricles. Myxoma

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  • (PMID = 17695732.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Portugal
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79. Abdel-Massih T, Sarkis A, Karam N, Allawi A, Arnaout S, Rachoin R, Abou-Jaoudé S, Azar R, Kassab R: [Epidemiology of cardiac tumors in adults in Lebanon]. J Med Liban; 2008 Jul-Sep;56(3):153-8
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  • The data were taken from the hospitals, the patients and/or their doctors by means of a questionnaire.
  • Fifty-seven cases of cardiac tumors were found, mainly myxomas in the left atrium.
  • The collected data urged us to propose a unique and homogenous strategy for diagnosis, treatment and follow-up of cardiac tumors in Lebanon.

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  • (PMID = 18792552.001).
  • [ISSN] 0023-9852
  • [Journal-full-title] Le Journal médical libanais. The Lebanese medical journal
  • [ISO-abbreviation] J Med Liban
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Lebanon
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80. Liu Y, Xu ML: Cardiac myxoma with glandular component: case report. Chin Med J (Engl); 2006 Jan 20;119(2):174-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac myxoma with glandular component: case report.
  • [MeSH-major] Heart Neoplasms / pathology. Myxoma / pathology

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  • (PMID = 16455003.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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81. Idrees MT, Hessler R, Terris D, Mixson C, Wang BY: Unusual polypoid laryngeal myxoma. Mt Sinai J Med; 2005 Jul;72(4):282-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual polypoid laryngeal myxoma.
  • Laryngeal polyps, known as vocal cord polyps, are often benign, reactive, polypoid, squamous mucosa with subepithelial hyalinization and edematous stroma.
  • Rarely, a benign mesenchymal myxoma occurring in the vocal cord will present as a polyp.
  • We report a case of a 46-year-old male who had a history of smoking and complained of hoarseness.
  • A polypoid vocal cord mass was removed and the pathologic finding was a benign myxoma.
  • [MeSH-major] Laryngeal Neoplasms / diagnosis. Myxoma / diagnosis. Polyps / diagnosis. Vocal Cords / pathology

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  • (PMID = 16021325.001).
  • [ISSN] 0027-2507
  • [Journal-full-title] The Mount Sinai journal of medicine, New York
  • [ISO-abbreviation] Mt. Sinai J. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34
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82. Takayama S, Sukekawa H, Arimoto T, Ikeno E, Komatu T, Rikimaru H, Hakamatsuka T, Takahashi T, Sugawara M: Lipomatous hypertrophy of the interatrial septum with cutaneous lipomatosis. Circ J; 2007 Jun;71(6):986-9
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  • In order to discriminate the myocardial lesion from myxoma and other benign conditions and malignant tumors, percutaneous transvenous biopsy was performed.
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Female. Humans. Lipomatosis / pathology. Myxoma / pathology

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  • (PMID = 17527001.001).
  • [ISSN] 1346-9843
  • [Journal-full-title] Circulation journal : official journal of the Japanese Circulation Society
  • [ISO-abbreviation] Circ. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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83. Can M, Tanboğa I, Gözübüyük G, Akgün T, Türkyilmaz E, Oduncu V, Kaymaz C: Severe tricuspid stenosis caused by myxoma originated from septal leaflet of tricuspid valve. Anadolu Kardiyol Derg; 2009 Apr;9(2):E4-5
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  • [Title] Severe tricuspid stenosis caused by myxoma originated from septal leaflet of tricuspid valve.
  • [MeSH-major] Heart Neoplasms / ultrasonography. Myxoma / ultrasonography. Tricuspid Valve. Tricuspid Valve Stenosis / etiology

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  • (PMID = 19357041.001).
  • [ISSN] 1308-0032
  • [Journal-full-title] Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • [ISO-abbreviation] Anadolu Kardiyol Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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84. Kerr PJ, Hone J, Perrin L, French N, Williams CK: Molecular and serological analysis of the epidemiology of myxoma virus in rabbits. Vet Microbiol; 2010 Jul 14;143(2-4):167-78
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  • [Title] Molecular and serological analysis of the epidemiology of myxoma virus in rabbits.
  • The epidemiology of myxoma virus was studied by serology and molecular analysis of restriction fragment length polymorphisms (RFLPs) in genomic DNA.
  • 159 isolates of myxoma virus were made over a period of 5 spring/summer epidemics from 12 field sites in south-eastern Australia.
  • This demonstrated how myxoma virus can potentially evolve by expansion of the inverted terminal repeat boundaries.
  • [MeSH-major] Myxoma virus / isolation & purification. Poxviridae Infections / veterinary. Tumor Virus Infections / veterinary
  • [MeSH-minor] Animals. Australia / epidemiology. Disease Outbreaks / veterinary. Rabbits. Time Factors

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  • [Copyright] (c) 2009. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20018465.001).
  • [ISSN] 1873-2542
  • [Journal-full-title] Veterinary microbiology
  • [ISO-abbreviation] Vet. Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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85. Cheng HP, Hsu CY, Chen CP, Su TH: Angiomyxoma of the umbilical cord. Taiwan J Obstet Gynecol; 2006 Dec;45(4):360-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomyxoma of the umbilical cord.
  • OBJECTIVE: Angiomyxoma is a rare tumor of the umbilical cord and is associated with increased perinatal morbidity and mortality.
  • We present a case of an angiomyxoma of the umbilical cord diagnosed in the second trimester, and highlight the contribution of color Doppler imaging to the early diagnosis of cord anomalies.
  • CONCLUSION: Angiomyxoma is a rare tumor of the umbilical cord and should be considered when using prenatal ultrasound for detection of cystic lesion.
  • [MeSH-major] Myxoma / ultrasonography. Pregnancy Complications, Neoplastic / ultrasonography. Ultrasonography, Prenatal. Umbilical Cord / ultrasonography

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  • (PMID = 17175501.001).
  • [ISSN] 1875-6263
  • [Journal-full-title] Taiwanese journal of obstetrics & gynecology
  • [ISO-abbreviation] Taiwan J Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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86. Yao F, Xu ZY, Liu YL, Han L: Infective mitral valve myxoma with coronary artery embolization: surgical intervention followed by prolonged survival. J Thorac Cardiovasc Surg; 2009 Mar;137(3):749-51
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  • [Title] Infective mitral valve myxoma with coronary artery embolization: surgical intervention followed by prolonged survival.
  • [MeSH-major] Coronary Artery Disease / complications. Coronary Artery Disease / surgery. Embolism / complications. Embolism / surgery. Heart Neoplasms / complications. Heart Neoplasms / surgery. Mitral Valve. Myxoma / complications. Myxoma / surgery. Neisseria lactamica. Neisseriaceae Infections / complications. Neisseriaceae Infections / surgery

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  • (PMID = 19258102.001).
  • [ISSN] 1097-685X
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. Zhang L, Stanford M, Liu J, Barrett C, Jiang L, Barclay AN, McFadden G: Inhibition of macrophage activation by the myxoma virus M141 protein (vCD200). J Virol; 2009 Sep;83(18):9602-7
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  • [Title] Inhibition of macrophage activation by the myxoma virus M141 protein (vCD200).
  • The M141 protein of myxoma virus (MYXV) is a viral CD200 homolog (also called vOX-2) that inhibits macrophage activation in infected rabbits.

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  • (PMID = 19570854.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United Kingdom / Medical Research Council / / G0400808; United Kingdom / Medical Research Council / / G0601169
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / M141R protein, myxoma virus; 0 / NF-kappa B; 0 / Tumor Necrosis Factor-alpha; 0 / Viral Proteins; 0 / antigens, CD200; 143011-72-7 / Granulocyte Colony-Stimulating Factor
  • [Other-IDs] NLM/ PMC2738222
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88. Muller A, Silva E, Abrantes J, Esteves PJ, Ferreira PG, Carvalheira JC, Nowotny N, Thompson G: Partial sequencing of recent Portuguese myxoma virus field isolates exhibits a high degree of genetic stability. Vet Microbiol; 2010 Jan 6;140(1-2):161-6
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  • [Title] Partial sequencing of recent Portuguese myxoma virus field isolates exhibits a high degree of genetic stability.
  • To study genetic changes underlying myxoma virus evolution in its new host, the European rabbit (Oryctolagus cuniculus), we sequenced selected genomic regions of nine recent virulent field strains and a live attenuated vaccine strain ("MAV", Germany).
  • DNA was extracted from cell culture passaged myxoma virus.
  • A total of 4863 bp (approximately 3% of the genome) of 10 regions spanning 12 genes of the myxoma viruses was sequenced and compared to the original virulent strain "Lausanne" and its attenuated field derivative strain "6918".
  • Our results support a high degree of genetic stability of myxoma virus over the past five decades.
  • [MeSH-major] Genetic Variation. Myxoma virus / genetics. Myxomatosis, Infectious / virology

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  • (PMID = 19709821.001).
  • [ISSN] 1873-2542
  • [Journal-full-title] Veterinary microbiology
  • [ISO-abbreviation] Vet. Microbiol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ FJ970492/ FJ970493/ FJ970494/ FJ970495/ FJ970496/ FJ970497/ FJ970498/ FJ970499/ FJ970500/ FJ970501/ FJ970502/ FJ970503/ FJ970504/ FJ970505/ FJ970506/ FJ970507
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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89. Alves C, Frangos E, Kalangos A, Perrenoud JJ: Left atrial myxoma: a rare but treatable source of systemic emboli in older patients. J Am Geriatr Soc; 2009 Nov;57(11):2151-3
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  • [Title] Left atrial myxoma: a rare but treatable source of systemic emboli in older patients.
  • [MeSH-major] Embolism / etiology. Heart Atria. Heart Neoplasms / complications. Myxoma / complications. Myxoma / ultrasonography
  • [MeSH-minor] Aged, 80 and over. Atrial Fibrillation / complications. Diagnosis, Differential. Echocardiography. Female. Heart Septum / surgery. Heart Septum / ultrasonography. Humans

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  • (PMID = 20121959.001).
  • [ISSN] 1532-5415
  • [Journal-full-title] Journal of the American Geriatrics Society
  • [ISO-abbreviation] J Am Geriatr Soc
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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90. Balami JS, Jones HW, Alp N, Dwight J, Casser C, Martin A, Winter L: Atrial myxoma presenting as transient ischaemic attack and acute coronary syndrome in an octogenarian. Age Ageing; 2006 Nov;35(6):644
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  • [Title] Atrial myxoma presenting as transient ischaemic attack and acute coronary syndrome in an octogenarian.
  • [MeSH-major] Heart Neoplasms / complications. Myocardial Ischemia / etiology. Myxoma / complications

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  • (PMID = 16951262.001).
  • [ISSN] 0002-0729
  • [Journal-full-title] Age and ageing
  • [ISO-abbreviation] Age Ageing
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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91. Stanford MM, Barrett JW, Nazarian SH, Werden S, McFadden G: Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells. J Virol; 2007 Feb;81(3):1251-60
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  • [Title] Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells.
  • Myxoma virus is a rabbit-specific poxvirus pathogen that also exhibits a unique tropism for human tumor cells and is dramatically oncolytic for human cancer xenografts.
  • Most tumor cell lines tested are permissive for myxoma infection in a fashion intimately tied to the activation state of Akt kinase.
  • A host range factor of myxoma virus, M-T5, directly interacts with Akt and mediates myxoma virus tumor cell tropism. mTOR is a regulator of cell growth and metabolism downstream of Akt and is specifically inhibited by rapamycin.
  • We report that treatment of nonpermissive human tumor cell lines, which normally restrict myxoma virus replication, with rapamycin dramatically increased virus tropism and spread in vitro.
  • This increased myxoma replication is concomitant with global effects on mTOR signaling, specifically, an increase in Akt kinase.
  • In contrast to the effects on human cancer cells, rapamycin does not increase myxoma virus replication in rabbit cell lines or permissive human tumor cell lines with constitutively active Akt.
  • This indicates that rapamycin increases the oncolytic capacity of myxoma virus for human cancer cells by reconfiguring the internal cell signaling environment to one that is optimal for productive virus replication and suggests the possibility of a potentially therapeutic synergism between kinase signaling inhibitors and oncolytic poxviruses for cancer treatment.
  • [MeSH-major] Myxoma virus / physiology. Neoplasms / therapy. Oncolytic Virotherapy / methods. Oncolytic Viruses / metabolism. Viral Proteins / metabolism

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  • (PMID = 17108021.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Viral Proteins; W36ZG6FT64 / Sirolimus
  • [Other-IDs] NLM/ PMC1797522
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92. Moore BA, Wine T, Burkey BB, Amedee RG, Butcher RB 2nd: Sphenoid sinus myxoma: case report and literature review. Ochsner J; 2008;8(4):166-71
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  • [Title] Sphenoid sinus myxoma: case report and literature review.
  • OBJECTIVES: We present the first known case in the English-language literature of a myxoma arising in the sphenoid sinus.
  • By describing the patient's clinical course and the salient features of this rare neoplasm, we seek to increase the awareness of the presentation, histological features, and treatment considerations for myxomas of the head and neck.
  • RESULTS: We describe the clinical course of a patient with a myxoma of the sphenoid sinus.
  • He remains without evidence of recurrent disease after 8 months.
  • CONCLUSIONS: Myxomas of the head and neck are rare neoplasms.

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  • (PMID = 21603497.001).
  • [ISSN] 1524-5012
  • [Journal-full-title] The Ochsner journal
  • [ISO-abbreviation] Ochsner J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3096368
  • [Keywords] NOTNLM ; Myxoma / neoplasms / sphenoid sinus
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93. Sareen D, Sethi A, Mrig S, Nigam S, Agarwal AK: Myxoma of the temporal bone: an uncommon neoplasm. Ear Nose Throat J; 2010 Mar;89(3):E18-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxoma of the temporal bone: an uncommon neoplasm.
  • Findings on the excision biopsy were consistent with a myxoma of the temporal bone.
  • At follow-up 2 years postoperatively, the patient remained disease-free.
  • To the best of our knowledge, this is only the 12th case of a myxoma of the temporal bone to be reported in the English-language literature.
  • [MeSH-major] Myxoma / pathology. Skull Neoplasms / pathology. Temporal Bone / pathology
  • [MeSH-minor] Cerebrospinal Fluid Otorrhea / diagnosis. Cerebrospinal Fluid Otorrhea / etiology. Child. Female. Headache / diagnosis. Headache / etiology. Hearing Disorders / diagnosis. Hearing Disorders / etiology. Humans. Tinnitus / diagnosis. Tinnitus / etiology. Vertigo / diagnosis. Vertigo / etiology

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  • (PMID = 20229465.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Kamler M, Wendt D, Szabó A, Wiese I, Kottenberg-Assenmacher E, Buck T, Jakob H: [Video-assisted cardiac valve surgery]. Herz; 2006 Aug;31(5):396-403
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  • PATIENTS AND METHODS: At the West German Heart Center Essen, 47 patients were operated using minimally invasive endoscopic techniques between January 2004 and April 2006 on the mitral valve (n = 31), mitral and tricuspid valve (n = 9), including mini-Maze procedure in two cases, as well as atrial septal defects (n = 5) and myxomas (n = 2).
  • After evaluation of efficacy and safety it is now the authors' exclusive approach to isolated atrioventricular valve disease with an ideal pain-free and cosmetic result.
  • [MeSH-minor] Adult. Aged. Echocardiography. Equipment Safety. Female. Follow-Up Studies. Heart Neoplasms / mortality. Heart Neoplasms / surgery. Heart Neoplasms / ultrasonography. Heart Septal Defects, Atrial / mortality. Heart Septal Defects, Atrial / surgery. Heart Septal Defects, Atrial / ultrasonography. Humans. Male. Middle Aged. Mitral Valve / surgery. Mitral Valve / ultrasonography. Myxoma / mortality. Myxoma / surgery. Myxoma / ultrasonography. Reoperation / statistics & numerical data. Surgical Instruments. Survival Analysis. Tricuspid Valve / surgery. Tricuspid Valve / ultrasonography

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  • (PMID = 16944058.001).
  • [ISSN] 0340-9937
  • [Journal-full-title] Herz
  • [ISO-abbreviation] Herz
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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95. Birim O, de Jong PL, Galema TW, Kappetein AP, Bogers AJ: Emergency surgery due to haematoma in a case of left atrial myxoma. Heart Lung Circ; 2006 Jun;15(3):191-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Emergency surgery due to haematoma in a case of left atrial myxoma.
  • Atrial myxomas generally do not require urgent surgery.
  • We report on a 78-year-old woman in whom transesophageal echography revealed a large left atrial myxoma.
  • The myxoma was surgically removed and showed a haematoma.
  • The most likely reason for the deteriorating condition was acute enlargement of the myxoma due to intramyxomal haemorrhage.
  • This case illustrates that the clinical condition of patients with symptomatic myxoma can deteriorate suddenly and require urgent surgical treatment.
  • [MeSH-major] Heart Neoplasms / therapy. Hematoma / surgery. Myxoma / surgery

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  • (PMID = 16455301.001).
  • [ISSN] 1443-9506
  • [Journal-full-title] Heart, lung & circulation
  • [ISO-abbreviation] Heart Lung Circ
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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96. Morag R, Fridman E, Mor Y: Aggressive angiomyxoma of the scrotum mimicking huge hydrocele: case report and literature review. Case Rep Med; 2009;2009:157624
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  • [Title] Aggressive angiomyxoma of the scrotum mimicking huge hydrocele: case report and literature review.
  • Aggressive Angiomyxoma (AAM) is a rare mesenchymal benign myxoid tumor of the pelvis and perineum which occurs almost exclusively in adult females.
  • The morphological picture and the special stains were compatible with aggressive angiomyxoma of the scrotum and peritoneum.

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  • (PMID = 19707474.001).
  • [ISSN] 1687-9627
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2728504
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97. Nalini G, Duggal R, Neelam A, Vanita S, Arvind R: Fine needle aspiration cytology in a case of recurrent aggressive angiomyxoma of vulva. Cytopathology; 2010 Jun;21(3):207-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration cytology in a case of recurrent aggressive angiomyxoma of vulva.
  • [MeSH-major] Myxoma / pathology. Neoplasm Recurrence, Local / pathology. Vulva / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 19843146.001).
  • [ISSN] 1365-2303
  • [Journal-full-title] Cytopathology : official journal of the British Society for Clinical Cytology
  • [ISO-abbreviation] Cytopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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98. Yao MS, Chen CY, Chin-Wei Chien J, Chen CL, Chan WP: Magnetic resonance imaging of gluteal intramuscular myxoma. Clin Imaging; 2007 May-Jun;31(3):214-6
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  • [Title] Magnetic resonance imaging of gluteal intramuscular myxoma.
  • Gluteal intramuscular myxomas with MR images have not been reported before.
  • Histologic diagnosis was compatible with intramuscular myxoma.
  • [MeSH-major] Muscle Neoplasms / radiography. Myxoma / radiography

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  • (PMID = 17449385.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Kato H, Kanematsu M, Sato E, Ito N, Furui T, Hirose Y: Magnetic resonance imaging findings of fibroepithelial polyp of the vulva: radiological-pathological correlation. Jpn J Radiol; 2010 Oct;28(8):609-12
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  • Although the MRI findings of fibroepithelial polyps of the vulva are often similar to those of aggressive angiomyxoma, angiomyofibroblastoma, and cellular angiofibroma, a fibroepithelial polyp should be considered when radiological images demonstrate the following features: stratiform hypointense areas surrounded by patchy hyperintense areas on T2-weighted MRI and hyperintense areas on T1-weighted MRI.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Neoplasms, Fibroepithelial / diagnosis. Polyps / diagnosis. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Young Adult

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  • MedlinePlus Health Information. consumer health - Vulvar Cancer.
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100. Uzun O, Wilson DG, Vujanic GM, Parsons JM, De Giovanni JV: Cardiac tumours in children. Orphanet J Rare Dis; 2007;2:11
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  • Cardiac tumours are benign or malignant neoplasms arising primarily in the inner lining, muscle layer, or the surrounding pericardium of the heart.
  • The vast majority of primary cardiac tumours in children are benign, whilst approximately 10% are malignant.
  • The frequency and type of cardiac tumours in adults differ from those in children with 75% being benign and 25% being malignant.
  • Myxomas are the most common primary tumours in adults constituting 40% of benign tumours.
  • Tumour biopsy with histological assessment remains the gold standard for confirmation of the diagnosis.
  • The outcome of surgical resection in symptomatic, non-myxomatous benign cardiac tumours is favourable.
  • [MeSH-major] Heart Neoplasms / diagnosis. Heart Neoplasms / epidemiology
  • [MeSH-minor] Adult. Age Distribution. Child. Child, Preschool. Female. Fetal Diseases / diagnosis. Fetal Diseases / epidemiology. Fetal Diseases / therapy. Fibroma / diagnosis. Fibroma / epidemiology. Fibroma / therapy. Global Health. Heart Transplantation. Hemangioma / diagnosis. Hemangioma / epidemiology. Hemangioma / therapy. Humans. Infant. Infant, Newborn. Male. Myxoma / diagnosis. Myxoma / epidemiology. Myxoma / therapy. Pregnancy. Prenatal Diagnosis / methods. Prevalence. Rhabdomyoma / diagnosis. Rhabdomyoma / epidemiology. Rhabdomyoma / therapy. Teratoma / diagnosis. Teratoma / epidemiology. Teratoma / therapy

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  • (PMID = 17331235.001).
  • [ISSN] 1750-1172
  • [Journal-full-title] Orphanet journal of rare diseases
  • [ISO-abbreviation] Orphanet J Rare Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 78
  • [Other-IDs] NLM/ PMC3225855
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