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1. Gimeno Argente V, Bosquet Sanz M, Ramírez Backhaus M, Trassierra Villa M, Arlandis Guzmán S, Jiménez Cruz JF: [Spontaneous retroperitoneal hemorrhage: our experience at last 10 years]. Actas Urol Esp; 2007 May;31(5):521-7
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  • RESULTS: The most common cause of retroperitoneal hemorrhage was renal angiomyolipoma rupture in 7 patients.

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  • (PMID = 17711171.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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2. Kumasaka T, Seyama K, Mitani K, Souma S, Kashiwagi S, Hebisawa A, Sato T, Kubo H, Gomi K, Shibuya K, Fukuchi Y, Suda K: Lymphangiogenesis-mediated shedding of LAM cell clusters as a mechanism for dissemination in lymphangioleiomyomatosis. Am J Surg Pathol; 2005 Oct;29(10):1356-66
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  • Lymphangioleiomyomatosis (LAM) affects exclusively women of reproductive age, involves the lungs and axial lymphatic system, and is frequently complicated with renal angiomyolipomas.


3. Rimon U, Duvdevani M, Garniek A, Golan G, Bensaid P, Ramon J, Morag B: Large renal angiomyolipomas: digital subtraction angiographic grading and presentation with bleeding. Clin Radiol; 2006 Jun;61(6):520-6
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  • [Title] Large renal angiomyolipomas: digital subtraction angiographic grading and presentation with bleeding.
  • MATERIALS AND METHODS: Thirty patients with 35 renal angiomyolipomas (size range 4-20 cm, mean 9.9 cm) underwent both digital subtraction angiography (DSA) and computed tomography (CT).
  • CONCLUSIONS: According to our criteria, large angiomyolipomas with minimal vascularity are less likely to bleed, and do not need prophylactic treatment.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology

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  • (PMID = 16713423.001).
  • [ISSN] 0009-9260
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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4. Nakashima A, Murakami Y, Uemura K, Hayashidani Y, Sudo T, Hashimoto Y, Arihiro K, Sueda T: Hepatic angiomyolipoma: a case report. Hiroshima J Med Sci; 2010 Mar;59(1):17-9
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  • [Title] Hepatic angiomyolipoma: a case report.
  • We experienced a rare case of hepatic angiomyolipoma (AML).
  • Morphological pattern and immunophenotype were consistent with hepatic angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / diagnosis. Liver Neoplasms / diagnosis

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  • (PMID = 20518257.001).
  • [ISSN] 0018-2052
  • [Journal-full-title] Hiroshima journal of medical sciences
  • [ISO-abbreviation] Hiroshima J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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5. Leflore A, McKenna PH, Schwartz BF: Laparoscopic cryotherapy for pediatric angiomyolipoma: the first report. J Endourol; 2007 Mar;21(3):321-4; discussion 324
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  • [Title] Laparoscopic cryotherapy for pediatric angiomyolipoma: the first report.
  • BACKGROUND AND PURPOSE: Renal cryotherapy for pediatric angiomyolipoma has never been reported in the literature.
  • CASE REPORT: A 14-year-old girl was being followed for a 2-cm left renal angiomyolipoma.
  • To our knowledge, this is the first case of pediatric renal angiomyolipoma managed with laparoscopic cryotherapy.

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  • [CommentIn] J Endourol. 2007 Sep;21(9):1123 [17941798.001]
  • (PMID = 17444779.001).
  • [ISSN] 0892-7790
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cellulose, Oxidized; 0 / FloSeal Matrix; 0 / Hemostatics; 82347-53-3 / Surgicel
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6. Rosenkrantz AB, Hecht EM, Taneja SS, Melamed J: Angiomyolipoma with epithelial cysts: mimic of renal cell carcinoma. Clin Imaging; 2010 Jan-Feb;34(1):65-8
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  • [Title] Angiomyolipoma with epithelial cysts: mimic of renal cell carcinoma.
  • Angiomyolipoma with epithelial cysts (AMLEC) is a rare variant of angiomyolipoma with minimal fat that contains epithelial-lined cysts and may mimic a cystic renal cell carcinoma.
  • [MeSH-major] Angiomyolipoma / complications. Angiomyolipoma / diagnosis. Kidney Diseases, Cystic / complications. Kidney Diseases, Cystic / diagnosis. Kidney Neoplasms / complications. Kidney Neoplasms / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed


7. Kosciesza S, Möhring C, Kirchner J, Rühl G, Goepel M: [Spontaneous renal angiomyolipoma rupture. Rare differential diagnosis of renal ruptures]. Urologe A; 2007 Aug;46(8):923-6
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  • [Title] [Spontaneous renal angiomyolipoma rupture. Rare differential diagnosis of renal ruptures].
  • [Transliterated title] Spontane Nierenruptur bei Angiomyolipom. Seltene Differentialdiagnose bei Nierenrupturen.
  • We report on a 50-year-old female patient with a retroperitoneal hematoma due to a spontaneous renal rupture for which an angiomyolipoma could only by diagnosed after the nephrectomy with histological work-up.
  • [MeSH-major] Angiomyolipoma / diagnosis. Hemorrhage / diagnosis. Kidney Diseases / diagnosis. Kidney Neoplasms / diagnosis

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  • (PMID = 17589819.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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8. Lipsky M, Richardson I, Tareen B: A case of pararenal angiomyolipoma arising from an existing exophytic angiomyolipoma. Can Urol Assoc J; 2010 Jun;4(3):E79-81
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  • [Title] A case of pararenal angiomyolipoma arising from an existing exophytic angiomyolipoma.
  • Computed tomography and magnetic resonance imaging revealed an exophytic mass in the right kidney consistent with an angiomyolipoma and an additional enhancing pararenal mass that contained fatty elements.
  • Differential diagnosis of the mass included liposarcoma and angiomyolipoma.
  • Upon exploration, the exophytic angiomyolipoma was found to be contiguous with the pararenal mass via an isthmus of fatty tissue.
  • Frozen sections were taken from both masses which confirmed that both were angiomyolipoma.
  • This is the first case reported in the literature wherein an angiomyolipoma extended extrarenally and formed a significantly larger pararenal mass.

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  • (PMID = 23293694.001).
  • [ISSN] 1920-1214
  • [Journal-full-title] Canadian Urological Association journal = Journal de l'Association des urologues du Canada
  • [ISO-abbreviation] Can Urol Assoc J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC3499926
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9. Urge T, Hora M, Hes O, Chudácek Z: [Renal angiomyolipoma, histology, diagnostics and therapy]. Cas Lek Cesk; 2005;144(12):821-3; discussion 824
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  • [Title] [Renal angiomyolipoma, histology, diagnostics and therapy].
  • [Transliterated title] Renální angiomyolipom, histologie, diagnostika a terapie.
  • BACKGROUND: Renal angiomyolipoma is a benign mezenchymal tumour with prevalence of 0.3-3% of all surgically resected renal tumours.
  • Angiomyolipoma occurred in 7 patients.
  • The angiomyolipoma was accidentally found in 2 cases of nephrectomy, which was indicated for other diagnosis.
  • This notation is not typical by any version of angiomyolipoma and we choose therefore surgical revision.
  • [MeSH-major] Angiomyolipoma. Kidney Neoplasms

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  • (PMID = 16389755.001).
  • [ISSN] 0008-7335
  • [Journal-full-title] Casopís lékar̆ů c̆eských
  • [ISO-abbreviation] Cas. Lek. Cesk.
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
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10. Chiarugi M, Martino MC, Pucciarelli M, Decanini L, Vignali C: Recurrent retroperitoneal hemorrhage in a patient with tuberous sclerosis complex: a case report. Cases J; 2008;1(1):424
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  • It is characterized by seizures, mental retardation and hamartomatous lesions, including facial angiofibroma, subependymal giant cell astrocytoma, cardiac rhabdomyoma and renal angiomyolipoma (AML).

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  • (PMID = 19115994.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2636789
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11. Raft J, Lalot JM, Meistelman C, Longrois D: [Renal angiomyolipoma rupture during pregnancy]. Gynecol Obstet Fertil; 2006 Oct;34(10):917-9
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  • [Title] [Renal angiomyolipoma rupture during pregnancy].
  • [Transliterated title] Rupture d'un angiomyolipome rénal lors d'une grossesse.
  • Subsequently, abdominal and thoracic computerised tomographic examination showed bilateral dysplasia of the kidneys and pulmonary cysts consistent with the diagnosis of renal angiomyolipoma and pulmonary lymphangioleiomyomatosis.
  • The case report is of interest because of the circumstances of discovery of the disease and because nephrectomy was not necessary to control the bleeding of the left kidney.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Pregnancy Complications, Neoplastic / diagnosis

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  • (PMID = 16996772.001).
  • [ISSN] 1297-9589
  • [Journal-full-title] Gynécologie, obstétrique & fertilité
  • [ISO-abbreviation] Gynecol Obstet Fertil
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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12. Marino G, Pedalino M, Di Primio OG, Piras D, Vella R, Verces E, Carbonatto P: [Wunderlich syndrome. Clinical and therapeutic aspects of a long-term experience]. Urologia; 2010 Jul-Sep;77(3):193-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: We present 19 cases of acute spontaneous hemoretroperitoneum or Wunderlich's syndrome diagnosed from 1996 to 2009, related to the following conditions: 7 renal carcinomas, 4 angiomyolipomas, 2 adrenal hemorrhages, 1 bleeding polycystic kidney, 2 hemorrhagic renal cysts and three cases of immunovasculitis.
  • Overall, 6 patients were treated with acetylsalicylic acid and 4 with dicumarolics for cardiovascular disease, while 13 patients were suffering from hypertension?
  • CONCLUSIONS: The spontaneous hemoretroperitoneum is a rare syndrome associated with acute kidney disease often unknown to the patient and only in selected cases with small hematoma; it is possible to perform arteriography with selective embolization of branches avoiding renal access surgery.
  • [MeSH-minor] Acute Disease. Humans. Retroperitoneal Space. Rupture, Spontaneous. Syndrome. Time Factors

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  • (PMID = 20931549.001).
  • [ISSN] 1724-6075
  • [Journal-full-title] Urologia
  • [ISO-abbreviation] Urologia
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] United States
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13. Bińkowska M, Debska M, Mazurek M, Słapa R, Debski R: Embolization of renal angiomyolipoma in pregnancy: case report. Ginekol Pol; 2009 Jun;80(6):449-52
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  • [Title] Embolization of renal angiomyolipoma in pregnancy: case report.
  • BACKGROUND: Renal angiomyolipoma is a rare benign tumour composed of adipose tissue, blood vessels and smooth muscles.
  • CONCLUSION: Embolization of renal angiomyolipoma bleeding vessels during pregnancy can be an effective therapeutic approach protecting against further bleeding and haemorrhagic shock thereby obviating the need to perform urgent surgery and allowing the woman to carry her pregnancy to term safely in outpatient setting.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy. Pregnancy Complications, Neoplastic / therapy

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  • (PMID = 19642603.001).
  • [ISSN] 0017-0011
  • [Journal-full-title] Ginekologia polska
  • [ISO-abbreviation] Ginekol. Pol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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14. Huang KH, Huang CY, Chung SD, Pu YS, Shun CT, Chen J: Malignant epithelioid angiomyolipoma of the kidney. J Formos Med Assoc; 2007 Feb;106(2 Suppl):S51-4
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  • [Title] Malignant epithelioid angiomyolipoma of the kidney.
  • Angiomyolipoma (AML) is a common benign renal tumor composed of thick-walled blood vessels, smooth muscle, and adipose tissue, but the malignant epithelioid variant is extremely rare.
  • The prognosis is poor in metastatic disease.

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  • (PMID = 17493897.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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15. López Fernández A, Lacasta García JD, Puig Giro R, Vicente de Vera P: [Kidney angiomyolipoma as aetiology of haemorragic shock]. Actas Urol Esp; 2008 Sep;32(8):855-7
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  • [Title] [Kidney angiomyolipoma as aetiology of haemorragic shock].
  • This is a case of retroperitoneal hematoma and hypovolemic shock as a presentation of renal angiomyolipoma, a rarely benign and asymptomatic tumor.
  • The evolution was favorable; it was not necessary to do more aggressive surgical handling neither to urgently remove the angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / complications. Kidney Neoplasms / complications. Shock, Hemorrhagic / etiology

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  • (PMID = 19013987.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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16. Linder B, Hong Y, Jarrett T: Intra-renal adrenal adenoma: a compelling addition to the differential diagnosis of renal mass. Int J Urol; 2009 Nov;16(11):912-4
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  • Laparoscopic renal exploration and biopsy revealed angiomyolipoma on frozen section.

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  • (PMID = 19863627.001).
  • [ISSN] 1442-2042
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Australia
  • [Number-of-references] 8
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17. Xu PJ, Shan Y, Yan FH, Ji Y, Ding Y, Zhou ML: Epithelioid angiomyolipoma of the liver: cross-sectional imaging findings of 10 immunohistochemically-verified cases. World J Gastroenterol; 2009 Sep 28;15(36):4576-81
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  • [Title] Epithelioid angiomyolipoma of the liver: cross-sectional imaging findings of 10 immunohistochemically-verified cases.
  • AIM: To retrospectively evaluate the computed tomography (CT)/magnetic resonance imaging (MRI) imaging features of epithelioid angiomyolipoma of the liver (Epi-HAML), with pathology as a reference.
  • METHODS: The CT/MRI findings (number, diameter, lobar location, and appearance of lesions) in a series of 10 patients with 12 pathologically proven epithelioid angiomyolipomas of the liver were retrospectively analyzed.
  • [MeSH-major] Angiomyolipoma / diagnosis. Liver Neoplasms / diagnosis

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  • (PMID = 19777618.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2752004
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18. Liu H, Wang HQ, Li X, Tang LO, Sun XL, Ji XR: [Malignant epithelioid angiomyolipoma of the kidney: report of a case]. Zhonghua Bing Li Xue Za Zhi; 2007 Sep;36(9):640-1
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  • [Title] [Malignant epithelioid angiomyolipoma of the kidney: report of a case].
  • [MeSH-major] Angiomyolipoma / pathology. Epithelioid Cells / pathology. Kidney Neoplasms / pathology

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  • (PMID = 18070459.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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19. Picken MM: The evolving concept of renal neoplasia: impact of emerging molecular and electron microscopic studies. Ultrastruct Pathol; 2005 May-Aug;29(3-4):277-82
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  • Tumors that have recently emerged from this group include tumors with translocations involving chromosome Xp11.2, carcinomas associated with neuroblastoma and epithelioid angiomyolipoma.

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  • (PMID = 16036881.001).
  • [ISSN] 0191-3123
  • [Journal-full-title] Ultrastructural pathology
  • [ISO-abbreviation] Ultrastruct Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
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20. Ramírez Daniel L, García Sabela L, Rey Jorge R, Calvo Antonio O: [Retroperitoneal angiomyolipoma: review of the literature and report of a new case]. Actas Urol Esp; 2010 Oct;34(9):815-7
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  • [Title] [Retroperitoneal angiomyolipoma: review of the literature and report of a new case].
  • [Transliterated title] Angiomiolipoma retroperitoneal: revisión de la literatura y reporte de un nuevo caso.
  • [MeSH-major] Angiomyolipoma. Puerperal Disorders. Retroperitoneal Neoplasms

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  • (PMID = 20843462.001).
  • [ISSN] 1699-7980
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] Spain
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21. Tyritzis SI, Adamakis I, Migdalis V, Vlachodimitropoulos D, Constantinides CA: Giant adrenal myelolipoma, a rare urological issue with increasing incidence: a case report. Cases J; 2009;2:8863
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  • The differential diagnosis comprised the adrenal myelolipoma, the retroperitoneal liposarcoma and the renal angiomyolipoma.

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  • [Cites] J Endourol. 2005 Jun;19(5):537-40 [15989440.001]
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  • (PMID = 19918346.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
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22. Marcheix B, Brouchet L, Lamarche Y, Renaud C, Gomez-Brouchet A, Hollington L, Chabbert V, Berjaud J, Dahan M: Pulmonary angiomyolipoma. Ann Thorac Surg; 2006 Oct;82(4):1504-6
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  • [Title] Pulmonary angiomyolipoma.
  • Extrarenal angiomyolipoma are benign lesions that have rarely been described in the thorax.
  • We present the clinical, radiographic, and pathologic findings of a pulmonary angiomyolipoma in a 63-year-old woman who had no diagnosis of tuberous sclerosis or lymphangioleiomyomatosis.
  • We believe that this report is one of the first descriptions of angiomyolipoma of the lung.
  • [MeSH-major] Angiomyolipoma / diagnosis. Lung Neoplasms / diagnosis

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  • (PMID = 16996965.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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23. Stein RJ, White WM, Goel RK, Irwin BH, Haber GP, Kaouk JH: Robotic laparoendoscopic single-site surgery using GelPort as the access platform. Eur Urol; 2010 Jan;57(1):132-6
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  • The final patient underwent partial nephrectomy without renal hilar clamping for an 11-cm angiomyolipoma with OR time of 180 min and EBL of 600 cm(3).

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  • [CommentIn] Eur Urol. 2010 Jan;57(1):137 [19361909.001]
  • [CommentIn] Eur Urol. 2010 Jan;57(1):136-7 [19361915.001]
  • (PMID = 19361916.001).
  • [ISSN] 1873-7560
  • [Journal-full-title] European urology
  • [ISO-abbreviation] Eur. Urol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Switzerland
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24. Pancholi V, Munjal K, Jain M, Munjal S, Agrawal R, Nandedkar S: Preoperative diagnosis of renal angiomyolipoma with fine needle aspiration cytology: a report of 3 cases. Acta Cytol; 2006 Jul-Aug;50(4):466-8
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  • [Title] Preoperative diagnosis of renal angiomyolipoma with fine needle aspiration cytology: a report of 3 cases.
  • BACKGROUND: Angiomyolipoma is a rare benign neoplasm, commonly involving the kidney.
  • CASES: We studied cases of renal angiomyolipoma (AML) presenting within 1 year with palpable renal masses confirmed on ultrasound to be of renal origin.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney / pathology. Kidney Neoplasms / diagnosis

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  • (PMID = 16901016.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Arnold RT, Myers DT: Visualization of renal angiomyolipoma on F-18 FDG PET/CT. Clin Nucl Med; 2009 Aug;34(8):539-40
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  • [Title] Visualization of renal angiomyolipoma on F-18 FDG PET/CT.
  • [MeSH-major] Angiomyolipoma / radiography. Angiomyolipoma / radionuclide imaging. Fluorodeoxyglucose F18. Kidney Neoplasms / radiography. Kidney Neoplasms / radionuclide imaging

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  • (PMID = 19617741.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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26. Mangal N, Sharma VK, Verma N, Agarwal AK, Sharma SP, Aneja S: Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases. J Cytol; 2009 Jul;26(3):97-101
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  • In the kidney, the maximum number of cases were of renal cell carcinoma (12-38%), followed by Wilm's tumor (6-19%), pyonephrosis (5-16%), renal cyst (4), angiomyolipoma (2), cortical pseudotumor (2), and tuberculosis (1).
  • The two cases of the adrenals were of angiomyolipoma and metastatic carcinoma.

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  • [ISSN] 0970-9371
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  • [Language] ENG
  • [Publication-type] Journal Article
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  • [Other-IDs] NLM/ PMC3168018
  • [Keywords] NOTNLM ; Ultrasound / fine needle aspiration cytology / retroperitoneum
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27. Azad NS, Aziz AB, Pervez S, Kayani N: Uterine perivascular epithelioid cell tumour presenting as a cervical mass. J Pak Med Assoc; 2006 Feb;56(2):83-4
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  • Perivascular Epithelioid Cell Tumour (PEComa) also known as myelomelanocytic tumours are uncommon, recently described mesenchymal tumours that include angiomyolipoma, clear cell "sugar" tumour of the lung, lymphangioleiomyoma and tumours composed predominantly of epithelioid cell morphology.


28. Tamai H, Takiguchi Y, Oka M, Shingaki N, Enomoto S, Shiraki T, Furuta M, Inoue I, Iguchi M, Yanaoka K, Arii K, Shimizu Y, Nakata H, Shinka T, Sanke T, Ichinose M: Contrast-enhanced ultrasonography in the diagnosis of solid renal tumors. J Ultrasound Med; 2005 Dec;24(12):1635-40
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  • RESULTS: Histopathologic examination of resected lesions showed malignancy in 26 patients (clear cell carcinoma, n = 18; papillary renal cell carcinoma, n = 6; collecting duct carcinoma, n = 1; and infiltrative urothelial carcinoma, n = 1) and benign tumors in 3 patients (oncocytoma, n = 2; and angiomyolipoma, n = 1).

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  • (PMID = 16301719.001).
  • [ISSN] 0278-4297
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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29. Uneda N, Imamura H, Tada S, Kamikawa K, Kudo K, Chikazawa H, Miyase S, Suko H, Hirota K, Urata J, Mitsuzaki K, Kamio T: [A patient with an angiomyolipoma of the liver in whom the course of enlargement could be confirmed]. Nihon Shokakibyo Gakkai Zasshi; 2008 Sep;105(9):1375-83
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  • [Title] [A patient with an angiomyolipoma of the liver in whom the course of enlargement could be confirmed].
  • Hepatectomy was performed, suggesting angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Disease Progression. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18772579.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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30. Peparini N, Di Matteo FM, Silvestri A, Caronna R, Chirletti P: Abdominal hypertension in Meigs' syndrome. Eur J Surg Oncol; 2008 Aug;34(8):938-42
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  • AIMS: Two cases of chronic abdominal hypertension in pseudo-Meigs' syndrome, one sustained by a large ovarian bilateral carcinoma and the other by a giant genital angiomyolipoma, are reported.
  • [MeSH-major] Angiomyolipoma / complications. Ascites / etiology. Compartment Syndromes / etiology. Genital Neoplasms, Female / complications. Meigs Syndrome / complications. Ovarian Neoplasms / complications

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  • (PMID = 17905563.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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31. Buurman H, Saeger W: Abnormalities in incidentally removed adrenal glands. Endocr Pathol; 2006;17(3):277-82
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  • Other indications for adrenalectomies were malignant tumors (urothelial carcinoma, squamous cell carcinoma, sarcoma, lymphoma, etc.) and benign findings (oncocytoma, angiomyolipoma, pyelonephritis, etc.).

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  • (PMID = 17308364.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
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32. Parfitt JR, Bella AJ, Izawa JI, Wehrli BM: Malignant neoplasm of perivascular epithelioid cells of the liver. Arch Pathol Lab Med; 2006 Aug;130(8):1219-22
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  • Although this group includes entities with distinct clinical features, such as angiomyolipoma, clear cell sugar tumor of the lung, and lymphangioleiomyomatosis, similar tumors have been documented in an increasing diversity of locations.
  • The term PEComa is now generally used in reference to these lesions that are not angiomyolipomas, clear cell sugar tumors, or lymphangioleiomyomatoses.

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  • (PMID = 16879028.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Bigelow D, Folio L: Radiology corner. Angiomyolipoma. Mil Med; 2008 Jan;173(1):xiii-xiv
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  • [Title] Radiology corner. Angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / diagnosis

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  • (PMID = 18251343.001).
  • [ISSN] 0026-4075
  • [Journal-full-title] Military medicine
  • [ISO-abbreviation] Mil Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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34. Ramamurthy S, Chick C: Re: the radiological diagnosis and treatment of renal angiomyolipoma--current status. Clin Radiol; 2010 Aug;65(8):669
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  • [Title] Re: the radiological diagnosis and treatment of renal angiomyolipoma--current status.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy

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  • [CommentOn] Clin Radiol. 2010 Feb;65(2):99-108 [20103431.001]
  • (PMID = 20599073.001).
  • [ISSN] 1365-229X
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
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35. Linam LE, Yu X, Calvo-Garcia MA, Rubio EI, Crombleholme TM, Bove K, Kline-Fath BM: Contribution of magnetic resonance imaging to prenatal differential diagnosis of renal tumors: report of two cases and review of the literature. Fetal Diagn Ther; 2010;28(2):100-8
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  • Enlargement of a kidney on prenatal imaging is usually due to hydronephrosis or cystic renal disease, and much less often results from solid tumors such as mesoblastic nephroma, Wilms' tumor, nephroblastomatosis, renal sarcoma, and angiomyolipoma.

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  • [Copyright] Copyright (c) 2010 S. Karger AG, Basel.
  • (PMID = 20587988.001).
  • [ISSN] 1421-9964
  • [Journal-full-title] Fetal diagnosis and therapy
  • [ISO-abbreviation] Fetal. Diagn. Ther.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
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36. Mongha R, Bansal P, Dutta A, Das RK, Kundu AK: Wunderlich's syndrome with hepatic angiomyolipoma in tuberous sclerosis. Indian J Cancer; 2008 Apr-Jun;45(2):64-6
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  • [Title] Wunderlich's syndrome with hepatic angiomyolipoma in tuberous sclerosis.
  • We present a patient of tuberous sclerosis complex with bilateral renal angiomyolipoma and hepatic angiomyolipoma with spontaneous retroperitoneal hemorrhage from right angiomyolipoma (Wunderlich's syndrome).
  • Hepatic angiomyolipoma was managed conservatively.
  • Wunderlich's syndrome has been found in around 10% of cases of renal angiomyolipomas.
  • Hepatic Angiomyolipoma is a benign mesenchymal neoplasm of the liver which is rarely reported in literature.
  • [MeSH-major] Angiomyolipoma / complications. Hemorrhage / etiology. Kidney Diseases / etiology. Kidney Neoplasms / complications. Liver Neoplasms / complications. Tuberous Sclerosis / complications


37. Akcali Y, Karahan OI, Kahriman G, Ceyran H, Balkanli S: Angiomyolipoma with cavoatrial extension: Part 2. Eur Urol; 2006 Oct;50(4):854-6
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  • [Title] Angiomyolipoma with cavoatrial extension: Part 2.
  • [MeSH-major] Angiomyolipoma / pathology. Heart Neoplasms / pathology. Kidney Neoplasms / pathology. Venae Cavae

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  • (PMID = 17024729.001).
  • [ISSN] 0302-2838
  • [Journal-full-title] European urology
  • [ISO-abbreviation] Eur. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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38. Gleeson FC, de la Mora Levy JG, Zhang L, Levy MJ: The differential broadens. EUS FNA appearance and cytological findings of pancreatic angiomyolipoma. JOP; 2008;9(1):67-70
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  • [Title] The differential broadens. EUS FNA appearance and cytological findings of pancreatic angiomyolipoma.
  • CONTEXT: Angiomyolipoma is a rare tumor characterized histologically by a mixture of spindle cells, adipose tissue, epithelioid cells, and vascular tissue.
  • CASE REPORT: We report a case of a 33-year-old female with an asymptomatic incidental right renal mass suggestive of an angiomyolipoma in conjunction with numerous pancreatic masses.
  • This is the first known reported EUS detection and FNA confirmation of angiomyolipoma metastatic to the pancreas and should now be added to the already broad differential of metastatic pancreatic tumors.
  • [MeSH-major] Angiomyolipoma / pathology. Angiomyolipoma / ultrasonography. Kidney Neoplasms / pathology. Kidney Neoplasms / ultrasonography. Pancreatic Neoplasms / secondary. Pancreatic Neoplasms / ultrasonography

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  • (PMID = 18182747.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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39. Wajed JR, Taylor-Robinson SD, Jackson JE, Stamp GW: Retroperitoneal haemorrhage in renal angiomyolipoma causing hepatic functional decompensation: a case report. J Med Case Rep; 2007;1:82
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  • [Title] Retroperitoneal haemorrhage in renal angiomyolipoma causing hepatic functional decompensation: a case report.
  • Prophylactic embolisation may be considered in some cases, depending on lesion size and patient co-morbidities.We present a case of retroperitoneal bleeding from a renal angiomyolipoma in a patient with known cirrhosis of the liver, which caused acute deterioration of liver function and consequent hepatic encephalopathy.
  • Such functional hepatic decompensation has not previously been reported in this context and we suggest the use of prophylactic embolisation for incidental renal angiomyolipomata, regardless of size, in all patients with chronic liver disease to prevent this potentially life-threatening complication.

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  • [Cites] J R Soc Med. 1999 Aug;92(8):414-5 [10656013.001]
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  • (PMID = 17822527.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2014766
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40. Bramer S, van Beek MW, Nieuwenhuijzen GA, Daniëls-Gooszen AW, van den Borne BE, de Hingh IH: [Acute abdominal pain and fever in a young woman as the first symptoms of lymphangioleiomyomatosis]. Ned Tijdschr Geneeskd; 2008 Jan 5;152(1):33-7
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  • A CT-scan of the abdomen and thorax confirmed the presence of a retroperitoneal mass but also revealed multiple renal angiomyolipomas and extensive cystic lesions in all lung fields.
  • LAM is a very rare disease affecting mostly women of childbearing age and presenting almost exclusively with pulmonary symptoms.
  • [MeSH-minor] Abdominal Pain / etiology. Acute Disease. Adult. Anti-Bacterial Agents / therapeutic use. Diagnosis, Differential. Female. Fever of Unknown Origin / etiology. Humans. Streptococcus agalactiae / drug effects. Streptococcus agalactiae / isolation & purification

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  • (PMID = 18240760.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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41. Bilbao I, Castro E, Dopazo C, Castro S, Allende E, Genesca J, Tallada N, Quiroga S, Margarit C: [Hepatic angiomyolipoma in two patients infected with hepatitis C virus]. Gastroenterol Hepatol; 2007 Apr;30(4):222-8
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  • [Title] [Hepatic angiomyolipoma in two patients infected with hepatitis C virus].
  • [Transliterated title] Angiomiolipoma hepático en dos pacientes con infección por el virus de la hepatitis C.
  • Histopathological examination and immunohistochemical findings gave the diagnosis of angiomyolipoma.
  • DISCUSSION AND CONCLUSION: The hepatic angiomyolipoma is a rare benign tumour, mimicking other liver tumours.
  • The hepatic angiomyolipoma consists of varing proportion of three elements, mature fat cells, smooth muscle cells and blood vessels.
  • It is not described its relation with HCV virus, thus we consider our cases as an coincident finding.
  • [MeSH-major] Angiomyolipoma / complications. Hepatitis C, Chronic / complications. Liver Neoplasms / complications

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  • (PMID = 17408551.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
  • [Number-of-references] 33
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42. Zhang J, Lefkowitz RA, Ishill NM, Wang L, Moskowitz CS, Russo P, Eisenberg H, Hricak H: Solid renal cortical tumors: differentiation with CT. Radiology; 2007 Aug;244(2):494-504
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  • PURPOSE: To retrospectively determine if solid renal cortical tumors can be differentiated on computed tomographic (CT) images on the basis of their morphologic features and enhancement patterns.
  • RESULTS: Of the 198 renal tumors (median size, 3.4 cm; range, 1.1-20.0 cm) included in this study, 108 (55%) were clear cell renal cell carcinomas (RCCs); 30 (15%), papillary lesions; 24 (12%), chromophobe adenomas; 14 (7%), oncocytomas; six (3%), lipid-poor angiomyolipomas; and 16 (8%), other or unclassified renal tumors.
  • Clear cell RCCs and oncocytomas tended to be hypervascular, chromophobe lesions and angiomyolipomas tended to enhance moderately, and papillary lesions were mostly hypovascular.

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  • (PMID = 17641370.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 4419T9MX03 / Iohexol
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43. Bissler JJ, McCormack FX, Young LR, Elwing JM, Chuck G, Leonard JM, Schmithorst VJ, Laor T, Brody AS, Bean J, Salisbury S, Franz DN: Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. N Engl J Med; 2008 Jan 10;358(2):140-51
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  • [Title] Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.
  • BACKGROUND: Angiomyolipomas in patients with the tuberous sclerosis complex or sporadic lymphangioleiomyomatosis are associated with mutations in tuberous sclerosis genes resulting in constitutive activation of the mammalian target of rapamycin (mTOR).
  • METHODS: We conducted a 24-month, nonrandomized, open-label trial to determine whether sirolimus reduces the angiomyolipoma volume in patients with the tuberous sclerosis complex or sporadic lymphangioleiomyomatosis.
  • Serial magnetic resonance imaging of angiomyolipomas and brain lesions, computed tomography of lung cysts, and pulmonary-function tests were performed.
  • The mean (+/-SD) angiomyolipoma volume at 12 months was 53.2+/-26.6% of the baseline value (P<0.001) and at 24 months was 85.9+/-28.5% of the baseline value (P=0.005).
  • At 24 months, five patients had a persistent reduction in the angiomyolipoma volume of 30% or more.
  • CONCLUSIONS: Angiomyolipomas regressed somewhat during sirolimus therapy but tended to increase in volume after the therapy was stopped.
  • [MeSH-major] Angiomyolipoma / drug therapy. Immunosuppressive Agents / therapeutic use. Lung Neoplasms / complications. Lymphangioleiomyomatosis / complications. Sirolimus / therapeutic use. Tuberous Sclerosis / complications


44. Seseke S, Schreiber M, Rebmann U, Seseke F: [Spontaneous perirenal hematomas in patients taking anticoagulation medication or having a bleeding diathesis]. Aktuelle Urol; 2008 May;39(3):215-8
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  • Bleeding is most commonly caused by renal tumours, especially angiomyolipomas.
  • [MeSH-minor] Aged. Angiomyolipoma / complications. Angiomyolipoma / diagnosis. Angiomyolipoma / surgery. Carcinoma, Renal Cell / complications. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / surgery. Diagnosis, Differential. Female. Flank Pain / etiology. Hematuria / etiology. Humans. Kidney Neoplasms / complications. Kidney Neoplasms / diagnosis. Kidney Neoplasms / surgery. Male. Middle Aged. Nephrectomy. Prognosis. Retroperitoneal Space. Rupture, Spontaneous. Shock, Hemorrhagic / etiology. Tomography, X-Ray Computed. von Willebrand Diseases / complications. von Willebrand Diseases / diagnosis

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  • (PMID = 18478495.001).
  • [ISSN] 0001-7868
  • [Journal-full-title] Aktuelle Urologie
  • [ISO-abbreviation] Aktuelle Urol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anticoagulants
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45. Handa U, Nanda A, Mohan H: Fine-needle aspiration of renal angiomyolipoma: a report of four cases. Cytopathology; 2007 Aug;18(4):250-4
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  • [Title] Fine-needle aspiration of renal angiomyolipoma: a report of four cases.
  • OBJECTIVE: Renal angiomyolipoma is an uncommon benign tumour composed of smooth muscle cells, blood vessels and adipose tissue.
  • METHODS: A retrospective analysis of four cases of angiomyolipoma diagnosed on fine-needle aspiration cytology (FNAC) during the period 1998-2004 was carried out.
  • CONCLUSION: The diagnosis of angiomyolipoma can be made by FNAC under image guidance and a cell block may be quite helpful in making a correct diagnosis.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney / pathology. Kidney Neoplasms / pathology

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  • (PMID = 17635162.001).
  • [ISSN] 0956-5507
  • [Journal-full-title] Cytopathology : official journal of the British Society for Clinical Cytology
  • [ISO-abbreviation] Cytopathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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46. Andaleeb A, Sachdev R: Jejunal angiomyolipoma. Indian J Pathol Microbiol; 2010 Oct-Dec;53(4):859
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  • [Title] Jejunal angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / diagnosis. Angiomyolipoma / pathology. Jejunal Neoplasms / diagnosis. Jejunal Neoplasms / pathology

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  • [CommentOn] Indian J Pathol Microbiol. 2007 Jul;50(3):568-9 [17883138.001]
  • (PMID = 21045449.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] India
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47. Patel S, Saito A, Yoneda Y, Hayano T, Shiratori K: Comparing enhancement and washout patterns of hepatic lesions between sonazoid-enhanced ultrasound and contrast-enhanced computed tomography. J Med Ultrason (2001); 2010 Oct;37(4):167-73
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  • There were 36 hepatocellular carcinomas, three intrahepatic cholangiocarcinomas, three metastatic lesions, eight focal nodular hyperplasias, two angiomyolipomas, and nine undetermined benign lesions.

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  • (PMID = 27278190.001).
  • [ISSN] 1346-4523
  • [Journal-full-title] Journal of medical ultrasonics (2001)
  • [ISO-abbreviation] J Med Ultrason (2001)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Contrast-enhanced computed tomography / Contrast-enhanced ultrasound / Hepatocellular carcinoma / Liver tumors / Sonazoid
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48. Ciftci AO, Sanlialp I, Tanyel FC, Buyukpamukçu N: The association of pulmonary lymphangioleiomyomatosis with renal and hepatic angiomyolipomas in a prepubertal girl: a previously unreported entity. Respiration; 2007;74(3):335-7
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  • [Title] The association of pulmonary lymphangioleiomyomatosis with renal and hepatic angiomyolipomas in a prepubertal girl: a previously unreported entity.
  • Pulmonary lymphangioleiomyomatosis (PLAM) is a rare, diffuse progressive interstitial lung disease that affects females of childbearing age and is characterized by diffuse proliferation of abnormal smooth muscle fibers predominantly developing in the lung and leading to cystic destruction.
  • A prepubertal 13-year-old girl with PLAM associated with renal and hepatic angiomyolipomas who was treated by nephroureterectomy and thoracoscopic pleurodesis is presented.
  • To the best of our knowledge, this is the first reported case of PLAM associated with renal and hepatic angiomyolipomas at the prepubertal age.
  • The most important clinical aid is to bear this rare entity in mind when a child presents with renal and/or hepatic angiomyolipomas.
  • [MeSH-major] Angiomyolipoma. Kidney Neoplasms. Liver Neoplasms. Lung Neoplasms. Lymphangioleiomyomatosis. Neoplasms, Multiple Primary


49. Castagnetti M, Vezzù B, Laverda A, Zampieri S, Rigamonti W: Urological counseling and followup in pediatric tuberous sclerosis complex. J Urol; 2007 Nov;178(5):2155-9
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  • Angiomyolipomas were the most common lesions (11 patients), followed by renal cysts (2) and polycystic kidney disease (2).
  • Renal failure developed in the 2 patients with polycystic kidney disease by the 2nd decade of life.
  • Overall, treatment was required in 2 cases of symptomatic angiomyolipoma.
  • [MeSH-minor] Age Distribution. Child. Child, Preschool. Disease Management. Female. Follow-Up Studies. Humans. Incidence. Infant. Infant, Newborn. Italy / epidemiology. Magnetic Resonance Imaging. Male. Prognosis. Retrospective Studies. Sex Distribution. Time Factors. Urography


50. Woodrum C, Nobil A, Dabora SL: Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors. J Transl Med; 2010 Feb 10;8:14
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  • Rapamycin has been shown to reduce the size of kidney angiomyolipomas associated with TSC; however, tumor regression is incomplete and kidney angiomyolipomas regrow after cessation of treatment.
  • RESULTS: TSC related kidney disease severity is 5-10 fold higher in A/J Tsc2+/- mice compared with C57BL/6 Tsc2+/- mice.
  • Similar to kidney angiomyolipomas associated with TSC, the severity of kidney cystadenomas increases with age in A/J Tsc2+/- mice.
  • [MeSH-minor] Animals. Antibodies, Monoclonal / therapeutic use. Antibodies, Monoclonal, Humanized. Antineoplastic Agents, Phytogenic / therapeutic use. Bevacizumab. Cystadenoma / drug therapy. Cystadenoma / pathology. Disease Models, Animal. Drug Administration Schedule. Female. Indoles / therapeutic use. Kidney Neoplasms / drug therapy. Kidney Neoplasms / pathology. Male. Mice. Mice, Inbred C57BL. Mice, Nude. Mice, Transgenic. Pyrroles / therapeutic use. Survival Rate. Vincristine / therapeutic use

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  • (PMID = 20146790.001).
  • [ISSN] 1479-5876
  • [Journal-full-title] Journal of translational medicine
  • [ISO-abbreviation] J Transl Med
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK066366
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibiotics, Antineoplastic; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents, Phytogenic; 0 / Indoles; 0 / Pyrroles; 0 / Tumor Suppressor Proteins; 2S9ZZM9Q9V / Bevacizumab; 4JG2LF96VF / tuberous sclerosis complex 2 protein; 5J49Q6B70F / Vincristine; EC 3.5.1.1 / Asparaginase; V99T50803M / sunitinib; W36ZG6FT64 / Sirolimus
  • [Other-IDs] NLM/ PMC2834646
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51. Suzuki T, Ueda Y, Shincho M, Mitsui Y, Higuchi Y, Maruyama T, Kondoh N, Nojima M, Yamamoto S, Hirota S, Shima H: [Myolipoma arising from the renal capsule: a case report]. Hinyokika Kiyo; 2008 May;54(5):349-52
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  • Although renal angiomyolipoma (AML) was suspected from these findings, we could not rule out a malignant tumor.

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  • (PMID = 18546859.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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52. Clements D, Asprey SL, McCulloch TA, Morris TA, Watson SA, Johnson SR: Analysis of the oestrogen response in an angiomyolipoma derived xenograft model. Endocr Relat Cancer; 2009 Mar;16(1):59-72
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  • [Title] Analysis of the oestrogen response in an angiomyolipoma derived xenograft model.
  • Angiomyolipomas are benign mesenchymal tumours of smooth muscle, blood vessels and fat which occur sporadically or associated with tuberous sclerosis and lymphangioleiomyomatosis (LAM), a rare cystic lung disease.
  • Angiomyolipoma and LAM are caused by loss of function of either the tuberous sclerosis-1 or -2 genes resulting in activation of p70S6kinase (S6K1) and uncontrolled cellular proliferation.
  • LAM and angiomyolipoma can be exacerbated by oestrogens but how this occurs is not understood.
  • To address this question, we created a xenograft tumour system in nude mice using immortalised angiomyolipoma cells.
  • Angiomyolipoma xenografts had active S6K1, p38, p42/44 MAPK and Akt; they grew more rapidly and had greater Akt phosphorylation after oestrogen treatment of tumour-bearing mice.
  • Biologically active PDGF-C was produced by primary angiomyolipoma cells in culture and PDGF-C protein was present in the neoplastic smooth muscle cells of 5/5 human angiomyolipoma and 4/5 LAM tissues examined by immunohistochemistry.
  • This model may prove useful for studying the biology and effect of drugs on angiomyolipoma and diseases related to TSC.
  • [MeSH-major] Angiomyolipoma / metabolism. Estrogens / pharmacology. Lung Neoplasms / metabolism. MAP Kinase Signaling System / drug effects. MAP Kinase Signaling System / physiology

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  • (PMID = 18988705.001).
  • [ISSN] 1351-0088
  • [Journal-full-title] Endocrine-related cancer
  • [ISO-abbreviation] Endocr. Relat. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Estrogens; 0 / Lymphokines; 0 / Multiprotein Complexes; 0 / Platelet-Derived Growth Factor; 0 / Proteins; 0 / Transcription Factors; 0 / mechanistic target of rapamycin complex 1; 0 / platelet-derived growth factor C; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 2.7.11.1 / Ribosomal Protein S6 Kinases, 70-kDa
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53. Rogers CG, Ditlev JA, Tan MH, Sugimura J, Qian CN, Cooper J, Lane B, Jewett MA, Kahnoski RJ, Kort EJ, Teh BT: Microarray gene expression profiling using core biopsies of renal neoplasia. Am J Transl Res; 2009;1(1):55-61
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  • Final pathologic assessment of kidney tumors demonstrated clear cell renal cell carcinoma (4), oncocytoma (1), angiomyolipoma (1) and adrenalcortical carcinoma (1).

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  • (PMID = 19966938.001).
  • [ISSN] 1943-8141
  • [Journal-full-title] American journal of translational research
  • [ISO-abbreviation] Am J Transl Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2776289
  • [Keywords] NOTNLM ; amplification / biopsy / cDNA microarray / gene expression profiling / kidney tumor
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54. Bishay VL, Crino PB, Wein AJ, Malkowicz SB, Trerotola SO, Soulen MC, Stavropoulos SW: Embolization of giant renal angiomyolipomas: technique and results. J Vasc Interv Radiol; 2010 Jan;21(1):67-72
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  • [Title] Embolization of giant renal angiomyolipomas: technique and results.
  • PURPOSE: To evaluate the efficacy and safety of prophylactic embolization of angiomyolipomas (AMLs) larger than 10 cm.
  • [MeSH-major] Angiomyolipoma / therapy. Antineoplastic Agents / therapeutic use. Ethanol / therapeutic use. Ethiodized Oil / therapeutic use. Kidney Neoplasms / therapy

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  • (PMID = 20123192.001).
  • [ISSN] 1535-7732
  • [Journal-full-title] Journal of vascular and interventional radiology : JVIR
  • [ISO-abbreviation] J Vasc Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Radiopharmaceuticals; 3K9958V90M / Ethanol; 8008-53-5 / Ethiodized Oil
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55. Ginat DT, Saad WE, Turba UC: Transcatheter renal artery embolization for management of renal and adrenal tumors. Tech Vasc Interv Radiol; 2010 Jun;13(2):75-88
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  • Transcatheter arterial embolization is a minimally invasive procedure that is increasingly used for the management of angiomyolipomas and to augment and/or palliate the management of malignant renal and adrenal neoplasms.
  • The most common indications for renal artery embolization include (1) prenephrectomy and preradiofrequency ablation infarction of renal tumors, (2) management of renal angiomyolipomas, (3) palliations of unresectable renal malignancy, and (4) malignant renal hemorrhage (life-threatening or chronic debilitating hematuria).
  • Although there is less extensive literature available regarding the use of transcatheter embolization of adrenal tumors, this technique appears to be effective and safe for palliation and preadrenalectomy of adrenal metastatic disease, adrenocortical carcinomas, as well as treatment of symptomatic aldosteronomas.

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20540917.001).
  • [ISSN] 1557-9808
  • [Journal-full-title] Techniques in vascular and interventional radiology
  • [ISO-abbreviation] Tech Vasc Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 31
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56. Schillinger F, Montagnac R: [Renal lesions in tuberous sclerosis]. Nephrol Ther; 2006 Jan;2 Suppl 2:S123-6
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  • Renal tumours, in tuberous sclerosis, are mainly benign and correspond to angiomyolipomas, multiple and bilateral, sometimes enormous with an hemorrhagic risk, frequently associated with cysts of variable size and number and seldom with high metastatic carcinomas.
  • There were angiomyolipomas in 23.1% of cases, cysts in 18.5%, both in 53.8% and malignancies in 12.3%.
  • [MeSH-minor] Angiomyolipoma / diagnosis. Angiomyolipoma / epidemiology. Angiomyolipoma / pathology. Glomerulosclerosis, Focal Segmental / etiology. Humans. Kidney Failure, Chronic / complications. Neoplasm Invasiveness


57. Milner J, McNeil B, Alioto J, Proud K, Rubinas T, Picken M, Demos T, Turk T, Perry KT Jr: Fat poor renal angiomyolipoma: patient, computerized tomography and histological findings. J Urol; 2006 Sep;176(3):905-9
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  • [Title] Fat poor renal angiomyolipoma: patient, computerized tomography and histological findings.
  • PURPOSE: We reviewed our experience with fat poor cases of angiomyolipoma.
  • MATERIALS AND METHODS: The records of patients with angiomyolipoma, as determined by pathological study, from 1998 to 2004 were reviewed by recording patient demographics and outcomes.
  • RESULTS: Histologically confirmed angiomyolipoma was found in 15 patients.
  • Of these 15 patients who underwent surgery 11 (73%) had unsuspected angiomyolipoma due to absent fat on computerized tomography and they underwent intervention for presumed renal cell carcinoma.
  • The percent of fat identified per high power field was less than 25% in 12 of 13 fat poor angiomyolipoma lesions (92%) compared to 2 of 4 classic lesions (50%) known to be angiomyolipoma before surgery (p = 0.04).
  • CONCLUSIONS: We suggest that a general definition of fat poor angiomyolipoma should be the failure of imaging to reveal fat within a lesion, thus, making it unsuspected at surgery.

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  • (PMID = 16890650.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Cohen MM, Pollock-BarZiv S, Johnson SR: Emerging clinical picture of lymphangioleiomyomatosis. Thorax; 2005 Oct;60(10):875-9
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  • Patients with TSC (n = 51) were less likely to report dyspnoea (p = 0.05) and 76.5% reported angiomyolipoma (p < 0.0001) compared with patients with sporadic LAM.


59. Yang B, Chen WH, Li QY, Xiang JJ, Xu RJ: Hepatic angiomyolipoma: dynamic computed tomography features and clinical correlation. World J Gastroenterol; 2009 Jul 21;15(27):3417-20
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  • [Title] Hepatic angiomyolipoma: dynamic computed tomography features and clinical correlation.
  • AIM: To study the dynamic computed tomography (CT) features of hepatic angiomyolipoma (AML) in patients with or without tuberous sclerosis complex (TSC).
  • [MeSH-major] Angiomyolipoma. Liver Neoplasms. Tomography, X-Ray Computed / methods. Tuberous Sclerosis

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  • (PMID = 19610144.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2712904
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60. Brimo F, Robinson B, Guo C, Zhou M, Latour M, Epstein JI: Renal epithelioid angiomyolipoma with atypia: a series of 40 cases with emphasis on clinicopathologic prognostic indicators of malignancy. Am J Surg Pathol; 2010 May;34(5):715-22
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  • [Title] Renal epithelioid angiomyolipoma with atypia: a series of 40 cases with emphasis on clinicopathologic prognostic indicators of malignancy.
  • As epithelioid cellular morphology can be seen in clinically benign usual angiomyolipomas (AMLs), we divide epithelioid AMLs into those without and with atypia, the latter category associated in the literature with malignant potential.
  • Of the 9 patients with malignant tumors, 4 died of the disease at 6, 12, 15, and 34 months after the original diagnosis was rendered, and 4 were alive with disease (mean follow-up period of 52 mo, range 24 to 72 mo).
  • [MeSH-major] Angiomyolipoma / pathology. Epithelioid Cells / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 20410812.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Li R, Zhang X, Hua X, Cai P, Zhong H, Guo Y, Ding S, Yan X: Real-time contrast-enhanced ultrasonography of resected and immunohistochemically proven hepatic angiomyolipomas. Abdom Imaging; 2010 Dec;35(6):676-82
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  • [Title] Real-time contrast-enhanced ultrasonography of resected and immunohistochemically proven hepatic angiomyolipomas.
  • PURPOSE: The purpose of this study was to assess real-time contrast-enhanced ultrasound in patients with hepatic angiomyolipomas with respect to contrast-enhancing kinetics and enhancement patterns.
  • All the 19 tumors were surgically resected and immunohistochemically proven sporadic hepatic angiomyolipomas.
  • CONCLUSION: Real-time contrast-enhanced ultrasonography can demonstrate typical imaging characteristics of hepatic angiomyolipomas in most cases, that is, inhomogeneous hyperenhancing pattern in arterial phase, prolonged hyperenhancement during portal and late phase with smooth and well-defined margin.
  • [MeSH-major] Angiomyolipoma / ultrasonography. Liver Neoplasms / ultrasonography

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  • (PMID = 20020286.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Contrast Media; 0 / Phospholipids; 0 / contrast agent BR1; 4419T9MX03 / Iohexol; 712BAC33MZ / iopromide; 84F6U3J2R6 / gadodiamide; K2I13DR72L / Gadolinium DTPA; WS7LR3I1D6 / Sulfur Hexafluoride
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62. Hiromura T, Nishioka T, Tomita K: Spontaneous rupture of renal angiomyolipoma: value of multidetector CT angiography for interventional therapy. Emerg Radiol; 2005 Dec;12(1-2):53-4
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  • [Title] Spontaneous rupture of renal angiomyolipoma: value of multidetector CT angiography for interventional therapy.
  • Renal angiomyolipomas have a high risk of rupture when they are large and associated with aneurysms.
  • When renal angiomyolipomas rupture, some patients go into shock.
  • [MeSH-major] Angiomyolipoma / diagnostic imaging. Kidney Neoplasms / diagnostic imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Acute Disease. Adult. Angiography. Back Pain / etiology. Contrast Media. Diagnosis, Differential. Embolization, Therapeutic. Female. Humans. Radiography, Interventional. Rupture, Spontaneous

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  • [Cites] Radiology. 2002 Oct;225(1):78-82 [12354988.001]
  • [Cites] AJR Am J Roentgenol. 2003 Jun;180(6):1633-8 [12760934.001]
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  • (PMID = 16317570.001).
  • [ISSN] 1070-3004
  • [Journal-full-title] Emergency radiology
  • [ISO-abbreviation] Emerg Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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63. Koizumi H, Ishihama K, Enomoto A, Kogo M: Angiomyolipoma of the tongue. Br J Oral Maxillofac Surg; 2008 Jan;46(1):e3-4
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  • [Title] Angiomyolipoma of the tongue.
  • We present a rare case of angiomyolipoma of the tongue in a 23-year-old man.
  • The oral angiomyolipoma followed a benign course with no recurrence after excision.
  • [MeSH-major] Angiomyolipoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 17629380.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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64. Hyams ES, Provet J: Angiomyolipoma of the left ureterovesical junction. Rev Urol; 2007;9(2):84-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomyolipoma of the left ureterovesical junction.
  • Angiomyolipoma (AML) is a benign tumor that typically consists of 3 tissue elements: thick-walled blood vessels, smooth muscle cells, and adipocytes.

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  • [Cites] Br J Radiol. 1998 Sep;71(849):977-9 [10195016.001]
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  • (PMID = 17592543.001).
  • [ISSN] 1523-6161
  • [Journal-full-title] Reviews in urology
  • [ISO-abbreviation] Rev Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1892627
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65. Micozkadioglu H, Koc Z, Ozelsancak R, Yildiz I: Rapamycin therapy for renal, brain, and skin lesions in a tuberous sclerosis patient. Ren Fail; 2010;32(10):1233-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Radiologic examination revealed additional brain and renal lesions consisting of tumors, cysts, and angiomyolipomas.
  • Imaging results showed reduction in tumor and angiomyolipoma volumes.
  • Oral rapamycin therapy can improve renal, brain, and skin lesions in TSC disease.


66. Ferreira S, Nogueira C, Ferreira D, Neves S, Taveira N: [Tuberous sclerosis with pulmonary involvment]. Rev Port Pneumol; 2010 Mar-Apr;16(2):339-44
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  • Tuberous sclerosis (TS) is a rare, sporadic or autosomal dominant disease characterized by the triad of seizures, mental retardation and angiofibromas.
  • We report the case of a 52 year -old female, nonsmoker, with a history of seizures in childhood and renal angiomyolipomas.
  • Chest CT performed for the evaluation of the disease detected thin-walled pulmonary cysts in both lungs.

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  • (PMID = 20437010.001).
  • [ISSN] 2172-6825
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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67. Kang M, Khandelwal N, Lal A, Singhal M, Mete U, Mandal AK: CT angiography in renal angiomyolipomas. Abdom Imaging; 2007 Nov;32(6):772-4
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  • [Title] CT angiography in renal angiomyolipomas.
  • Renal angiomyolipomas are fat containing tumours, which are associated with a strong risk of hemorrhage due to the presence of abnormal vessels and pseudoaneurysms.
  • We present three cases of ruptured renal angiomyolipomas with multiple or large pseudoaneurysms diagnosed by CT angiography which enabled emergent endovascular intervention; and propose CT angiography as the diagnostic modality of choice, particularly in emergency situations.
  • [MeSH-major] Angiomyolipoma / radiography. Kidney Neoplasms / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 17285401.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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68. Sooriakumaran P, Gibbs P, Coughlin G, Attard V, Elmslie F, Kingswood C, Taylor J, Corbishley C, Patel U, Anderson C: Angiomyolipomata: challenges, solutions, and future prospects based on over 100 cases treated. BJU Int; 2010 Jan;105(1):101-6
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  • OBJECTIVE: To examine the presentation, management and outcomes of patients with renal angiomyolipoma (AML) over a period of 10 years, at St George's Hospital, London, UK.
  • The 77 patients with stable disease were followed up with surveillance imaging, and 25 received interventions, some more than one.
  • [MeSH-major] Angiomyolipoma / therapy. Catheter Ablation / methods. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy. Nephrectomy / methods. Tuberous Sclerosis / therapy


69. Wang KL, Weinrach DM, Luan C, Han M, Lin F, Teh BT, Yang XJ: Renal papillary adenoma--a putative precursor of papillary renal cell carcinoma. Hum Pathol; 2007 Feb;38(2):239-46
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  • Seven papillary adenomas (18%) occurred in the setting of acquired polycystic kidney disease (APKD), 6 in clear-cell RCCs, 3 in chromophobe RCCs, 2 in end-stage kidney disease, 1 in oncocytoma, 1 in angiomyolipoma, and 1 in renal schwannoma.
  • [MeSH-minor] Adenocarcinoma, Clear Cell / enzymology. Adenocarcinoma, Clear Cell / pathology. Adenoma. Adenoma, Oxyphilic / enzymology. Adenoma, Oxyphilic / pathology. Adult. Aged. Aged, 80 and over. Angiomyolipoma / enzymology. Angiomyolipoma / pathology. Disease Progression. Female. Glutathione Transferase / analysis. Humans. Immunohistochemistry. Isoenzymes / analysis. Kidney / enzymology. Kidney / pathology. Kidney Failure, Chronic / enzymology. Kidney Failure, Chronic / pathology. Male. Middle Aged. Models, Biological. Polycystic Kidney Diseases / enzymology. Polycystic Kidney Diseases / pathology. Racemases and Epimerases / analysis

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  • (PMID = 17056094.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Isoenzymes; EC 2.5.1.18 / Glutathione Transferase; EC 2.5.1.18 / glutathione S-transferase alpha; EC 5.1.- / Racemases and Epimerases; EC 5.1.99.4 / alpha-methylacyl-CoA racemase
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70. Genega EM, Ghebremichael M, Najarian R, Fu Y, Wang Y, Argani P, Grisanzio C, Signoretti S: Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. Am J Clin Pathol; 2010 Dec;134(6):873-9
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  • We evaluated its immunohistochemical expression in 317 primary and 42 metastatic renal neoplasms (186 clear cell, 52 papillary, 35 chromophobe, 47 unclassified, and 15 Xp11.2 translocation renal cell carcinomas [RCCs]; 26 oncocytomas; 2 metanephric adenomas; 1 urothelial carcinoma; 1 mixed epithelial and stromal tumor; and 1 angiomyolipoma); 7 neoplasms were unknown as to whether they were primary or metastatic.

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  • (PMID = 21088149.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA101942; United States / NCI NIH HHS / CA / P50CA101942
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; EC 4.2.1.1 / CA9 protein, human; EC 4.2.1.1 / Carbonic Anhydrases
  • [Other-IDs] NLM/ NIHMS511251; NLM/ PMC3778911
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71. Msezane L, Chang A, Shikanov S, Deklaj T, Katz MH, Shalhav AL, Lifshitz DA: Laparoscopic nephron-sparing surgery in the management of angiomyolipoma: a single center experience. J Endourol; 2010 Apr;24(4):583-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic nephron-sparing surgery in the management of angiomyolipoma: a single center experience.
  • BACKGROUND AND PURPOSE: Angioembolization is often the first-line treatment for patients with renal angiomyolipoma (AML).

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  • (PMID = 20423289.001).
  • [ISSN] 1557-900X
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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72. Muttarak M, Pattamapaspong N, Lojanapiwat B, Chaiwun B: Renal angiomyolipoma with bleeding. Biomed Imaging Interv J; 2007 Oct;3(4):e8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Renal angiomyolipoma with bleeding.

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  • [Cites] Radiographics. 1999 Mar-Apr;19(2):555-8 [10194800.001]
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  • (PMID = 21614302.001).
  • [ISSN] 1823-5530
  • [Journal-full-title] Biomedical imaging and intervention journal
  • [ISO-abbreviation] Biomed Imaging Interv J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
  • [Other-IDs] NLM/ PMC3097681
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73. Sharara AI, Tawil A: Angiomyolipoma of the colon. Clin Gastroenterol Hepatol; 2005 Sep;3(9):A35
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  • [Title] Angiomyolipoma of the colon.
  • [MeSH-major] Angiomyolipoma / diagnosis. Colonic Neoplasms / diagnosis

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  • (PMID = 16234016.001).
  • [ISSN] 1542-3565
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Minervini A, Giubilei G, Masieri L, Lanzi F, Serni S, Carini M: Simple enucleation for the treatment of renal angiomyolipoma. BJU Int; 2007 Apr;99(4):887-91
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  • [Title] Simple enucleation for the treatment of renal angiomyolipoma.
  • OBJECTIVES: To report on the role of simple enucleation for treating renal angiomyolipoma (AML) in a series of patients treated in our department.
  • [MeSH-major] Angiomyolipoma / surgery. Kidney Neoplasms / surgery. Nephrectomy / methods

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  • (PMID = 17233805.001).
  • [ISSN] 1464-4096
  • [Journal-full-title] BJU international
  • [ISO-abbreviation] BJU Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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75. Schreiner A, Daneshmand S, Bayne A, Countryman G, Corless CL, Troxell ML: Distinctive morphology of renal cell carcinomas in tuberous sclerosis. Int J Surg Pathol; 2010 Oct;18(5):409-18
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  • The syndrome is characterized by hamartomas and neoplastic lesions, including angiomyolipomas of the kidney and other organs.
  • Renal cell carcinoma (RCC) in tuberous sclerosis remains relatively poorly characterized because historical studies were confounded by the inclusion of epithelioid angiomyolipomas.
  • The authors present a patient with tuberous sclerosis and bilateral renal lesions, including multiple minute angiomyolipomas, cortical cysts, and 4 separate RCCs of unclassified type.

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  • (PMID = 19403547.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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76. Bora A, Soni A, Sainani N, Patkar D: Emergency embolization of a bleeding renal angiomyolipoma using polyvinyl alcohol particles. Diagn Interv Radiol; 2007 Dec;13(4):213-6
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  • [Title] Emergency embolization of a bleeding renal angiomyolipoma using polyvinyl alcohol particles.
  • Angiomyolipomas (AMLs) are hamartomatous lesions consisting of abnormal blood vessels, smooth muscle, and adipose tissue.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic. Hemorrhage / therapy. Kidney Neoplasms / therapy

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  • (PMID = 18092296.001).
  • [ISSN] 1305-3825
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Sclerosing Solutions; 9002-89-5 / Polyvinyl Alcohol
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77. Lillo ME, Marín MD, Frutos L, Navarro T, Coronado M, Martín Curto LM: [Renal angiomyolipoma and fever: assessment with isotopic renogram and 67Ga scintigraphy]. Rev Esp Med Nucl; 2005 Sep-Oct;24(5):322-5
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  • [Title] [Renal angiomyolipoma and fever: assessment with isotopic renogram and 67Ga scintigraphy].
  • [Transliterated title] Angiomiolipoma renal y fiebre: valoración mediante renograma isotópico y gammagrafía con 67Ga.
  • Abdominal CT is performed because of suspicion of active bleeding in right hemiabdomen, following rupture of right angiomyolipoma, treated by selective arterial embolization.
  • [MeSH-major] Angiomyolipoma / radionuclide imaging. Gallium Radioisotopes. Kidney Neoplasms / radionuclide imaging. Radioisotope Renography

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  • (PMID = 16194465.001).
  • [ISSN] 0212-6982
  • [Journal-full-title] Revista española de medicina nuclear
  • [ISO-abbreviation] Rev Esp Med Nucl
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Gallium Radioisotopes
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78. Sugimoto T, Morita Y, Kashiwagi A: Spontaneous hemorrhage from renal angiomyolipoma presenting with fever of unknown origin. Intern Med; 2007;46(11):793-4
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  • [Title] Spontaneous hemorrhage from renal angiomyolipoma presenting with fever of unknown origin.
  • [MeSH-major] Angiomyolipoma / complications. Fever of Unknown Origin / etiology. Hematoma / complications. Kidney Neoplasms / complications

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  • (PMID = 17541239.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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79. Limaïem F, Mekni A, Chelly I, Nouira Y, Khadija B, Haouet S, Kchir N, Horchani A, Moncef Z: Renal epithelioid angiomyolipoma: a case report and literature review. Pathologica; 2008 Feb;100(1):31-5
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  • [Title] Renal epithelioid angiomyolipoma: a case report and literature review.
  • BACKGROUND: Renal epithelioid angiomyolipoma is a recently recognized variant of angiomyolipoma, closely simulating renal cell carcinoma both clinically and histologically.
  • Only a relatively small number of cases of epithelioid angiomyolipoma of the kidney have been reported.
  • OBSERVATION: We report herein a new case of renal epithelioid angiomyolipoma in a 38-year-old male with no stigmata of tuberous sclerosis.
  • The patient showed no evidence of recurrence or metastatic disease one year after radical nephrectomy.
  • CONCLUSIONS: Epithelioid angiomyolipoma may be locally aggressive and can metastasise; therefore, long-term post-operative follow-up is mandatory.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology

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  • (PMID = 18686524.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 27
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80. McClean JM, Kercher KW, Mah NA, Zerey M, Heniford BT, Irby PB, Burks RT, Weida C, Teigland CM: Strategies in the management of renal tumors amenable to partial nephrectomy. Surg Endosc; 2009 Sep;23(9):2161-6
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  • Thirty-six (78%) tumors were renal cell carcinoma, seven (15%) were oncocytomas, and three (7%) were angiomyolipomas.
  • [MeSH-minor] Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / surgery. Adult. Aged. Aged, 80 and over. Angiomyolipoma / pathology. Angiomyolipoma / surgery. Electrocoagulation. Female. Follow-Up Studies. Hemostasis, Surgical. Humans. Male. Middle Aged. Postoperative Complications / epidemiology. Retrospective Studies. Treatment Outcome. Video-Assisted Surgery

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  • [Cites] Surg Endosc. 2003 Dec;17(12):1889-95 [14569452.001]
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  • (PMID = 18594916.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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81. Ramantani G, Niggemann P, Hahn G, Näke A, Fahsold R, Lee-Kirsch MA: Unusual radiological presentation of tuberous sclerosis complex with leptomeningeal angiomatosis associated with a hypomorphic mutation in the TSC2 gene. J Child Neurol; 2009 Mar;24(3):333-7
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  • At the age of 13, multiple renal angiomyolipomas and a single hypomelanotic macule were found, and subsequent imaging revealed several cortical tuberi.

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  • [CommentIn] J Child Neurol. 2009 Mar;24(3):263-6 [19258284.001]
  • (PMID = 19258292.001).
  • [ISSN] 1708-8283
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; 4JG2LF96VF / tuberous sclerosis complex 2 protein
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82. Tickoo SK, Gopalan A, Tu JJ, Harik LR, Al-Ahmadie HA, Fine SW, Olgac S, Reuter VE: Estrogen and progesterone-receptor-positive stroma as a non-tumorous proliferation in kidneys: a possible metaplastic response to obstruction. Mod Pathol; 2008 Jan;21(1):60-5
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  • The presence of estrogen and progesterone-receptor-positive stroma is well known in renal mixed epithelial and stromal tumor, cystic nephroma, and angiomyolipoma with epithelial cysts.
  • In six cases, the nephrectomies were performed for a non-functional kidney, and in three for tumors (one each of chromophobe, clear cell, and acquired cystic disease-associated renal cell carcinoma).
  • In one it was present at the periphery of an acquired cystic disease-associated renal cell carcinoma, as well as around non-tumorous cysts.
  • The only common finding in all cases was a generalized or segmental hydronephrosis, or tumor compression-related focal obstruction.

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  • (PMID = 17873894.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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83. Pedemonte JG, Degiovanni D, Pusterla D, Reibel C, Di Nucci J, Boccio C, Degiovanni R, Dotta A: [Angiomyolipoma and Lenk syndrome: case report]. Actas Urol Esp; 2008 Sep;32(8):850-4
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  • [Title] [Angiomyolipoma and Lenk syndrome: case report].
  • [Transliterated title] Triada de Lenk como presentación clínica del angiomiolipoma.
  • Angiomyolipoma (AML) is a benign clonal neoplasm that consists of varying amounts of mature adipose tissue, smooth muscle, and thick-walled vessels.
  • We present the case of a fifty-nine-year old patient with an angiomyolipoma and massive retroperitoneal hemorrhage with Lenk syndrome.
  • [MeSH-major] Angiomyolipoma / complications. Flank Pain / complications. Hematuria / complications. Kidney Diseases / complications. Kidney Neoplasms / complications

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  • (PMID = 19013986.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas espanolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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84. Tillou X, Boutemy F, Remond A, Petit J: [Contribution of curative and preventive embolization for renal angiomyolipomas treatment]. Prog Urol; 2010 Oct;20(9):627-32
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  • [Title] [Contribution of curative and preventive embolization for renal angiomyolipomas treatment].
  • OBJECTIVE: The purpose of this study was to present the role of embolization in the treatment of kidney angiomyolipomas (AML), for preventive care or in case of bleeding.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic. Kidney Neoplasms / therapy

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20951930.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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85. Kawauchi S, Nawata H, Yamagata Y, Yaegashi H, Fukunaga M, Moriya T, Furuya T, Sugino N, Sasaki K: Chromosomal imbalances detected by comparative genomic hybridization provide evidence that HMB-45-negative uterine angiomyolipomas belong to the PEComa family. Histopathology; 2010 Jun;56(7):974-7
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  • [Title] Chromosomal imbalances detected by comparative genomic hybridization provide evidence that HMB-45-negative uterine angiomyolipomas belong to the PEComa family.
  • [MeSH-major] Angiomyolipoma / genetics. Antigens, Neoplasm / genetics. Chromosome Aberrations. Neoplasm Proteins / genetics. Perivascular Epithelioid Cell Neoplasms / genetics. Uterine Neoplasms / genetics

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  • (PMID = 20636800.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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86. Walsh SN, Sangüeza OP: PEComas: a review with emphasis on cutaneous lesions. Semin Diagn Pathol; 2009 Aug;26(3):123-30
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  • The connection between angiomyolipoma (AML) of the kidney, clear cell sugar tumor (CCST) of the lung, and pulmonary lymphangioleiomyoma (LAM), was progressively discovered because of the histologic and immunophenotypic similarities between the three tumors and their frequent association with tuberous sclerosis complex (TSC).

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  • [CommentIn] Am J Dermatopathol. 2016 Feb;38(2):165-6 [26825164.001]
  • (PMID = 20043511.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Desmin; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
  • [Number-of-references] 65
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87. Huo L, Sugimura J, Tretiakova MS, Patton KT, Gupta R, Popov B, Laskin WB, Yeldandi A, Teh BT, Yang XJ: C-kit expression in renal oncocytomas and chromophobe renal cell carcinomas. Hum Pathol; 2005 Mar;36(3):262-8
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  • Recently, KIT has been reported to be a marker for chromophobe renal cell carcinoma (RCC) and renal angiomyolipoma.
  • Furthermore, comprehensive immunohistochemical analysis of KIT protein using a monoclonal antibody was performed in 226 renal tumors including chromophobe RCC (n=40), oncocytoma (n=41), clear-cell RCC (n=40), renal angiomyolipoma (n=29), and papillary RCC (n=21) on tissue microarrays (TMAs) and was compared with immunostaining results from 25 chromophobe RCCs and 30 oncocytomas using standard sections.
  • Immunohistochemical expression of KIT was found in most chromophobe RCCs (95% in TMAs and 96% in conventional sections) and oncocytomas (88% in TMAs and 100% in conventional sections) but was infrequently observed in renal angiomyolipomas (17%), papillary RCCs (5%), and clear-cell RCCs (3%).
  • Furthermore, the average KIT immunoreactivity in TMAs was stronger in chromophobe RCC (1.93) and oncocytoma (2.07) than in other subtypes of renal tumors tested, including angiomyolipomas (0.17), papillary RCCs (0.05), and clear-cell RCCs (0.03).

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  • (PMID = 15791570.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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88. Teodorovich OV, Ternovoĭ SK, Vlasova IS, Zabrodina NB, Fominykh EV, Kesov IaE: [Comparative analysis of modern combined methods in diagnosis of renal cell carcinoma]. Urologiia; 2006 Sep-Oct;(5):3-6, 11
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  • To ascertain the role of multispiral computed tomography (MSCT) in diagnosis of renal cell carcinoma (RCC) and to propose optimal diagnostic policy in RCC patients, we examined 63 patients with suspected renal tumor: 37 (59%) males and 26 (41%) females, age 47-77 ages, mean age 54.2+/-1.5 years, duration of the disease from 1 month to 7 years.
  • Benign renal tumors were detected in 8 (14.2%) patients, giant cysts of the kidneys--in 5 cases, benign renal tumors--in 3 cases, adenoma--in 2 cases, angiomyolipoma--in 1 case.

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  • (PMID = 17444144.001).
  • [ISSN] 1728-2985
  • [Journal-full-title] Urologii︠a︡ (Moscow, Russia : 1999)
  • [ISO-abbreviation] Urologiia
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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89. Sokolova IA, Matsko DE, Hes O, Michal M: [Mucinous tubular and spindle-cell carcinoma of the kidney]. Arkh Patol; 2006 Jul-Aug;68(4):14-5
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  • Mucinous tubular and spindle-cell carcinoma of the kidney should be differentiated from angiomyolipoma with the preponderance of a leiomyomatous component, renal smooth muscle neoplasms, metanephrotic adenoma, and renal cell carcinoma with sarcomatoid differentiation.

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  • (PMID = 16986488.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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90. Aliasgari M, Ghadian A: Coincidence of angiomyolipoma and pheochromocytoma. Urol J; 2006;3(1):61-3; discussion 63-4
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  • [Title] Coincidence of angiomyolipoma and pheochromocytoma.

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  • (PMID = 17590855.001).
  • [ISSN] 1735-1308
  • [Journal-full-title] Urology journal
  • [ISO-abbreviation] Urol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
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91. Nassaf M, Afif H, Aichane A, Ridai M, Souabny A, El Ouafi N, Bouayad Z: [Recurrent pneumothorax revealing a tuberous sclerosis complex]. Rev Med Interne; 2008 Mar;29(3):252-4
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  • We report a 29-year-old woman who presented with recurrent pneumothorax in whom the diagnosis of TSC relied on the existence of family history (child with cardiac rhabdomyome), skin lesions, pulmonary lymphangiomyomatosis, hepatic lipomas, renal angiomyolipomas, uterine myomas and cerebral lesions on MRI.


92. Mikami S, Oya M, Mukai M: Angiomyolipoma with epithelial cysts of the kidney in a man. Pathol Int; 2008 Oct;58(10):664-7
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  • [Title] Angiomyolipoma with epithelial cysts of the kidney in a man.
  • Angiomyolipoma (AML) is a well-characterized tumor composed of vascular, smooth muscle and adipose elements.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Diseases, Cystic / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Actins / metabolism. Antigens, Neoplasm / metabolism. Biomarkers, Tumor / metabolism. Desmin / metabolism. Disease-Free Survival. Hematuria. Humans. Male. Melanoma-Specific Antigens. Middle Aged. Neoplasm Proteins / metabolism. Neprilysin / metabolism. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism

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  • (PMID = 18801088.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Desmin; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; EC 3.4.24.11 / Neprilysin
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93. Park HK, Zhang S, Wong MK, Kim HL: Clinical presentation of epithelioid angiomyolipoma. Int J Urol; 2007 Jan;14(1):21-5
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  • [Title] Clinical presentation of epithelioid angiomyolipoma.
  • OBJECTIVE: Epithelioid angiomyolipomas (AML) of the kidney are malignant tumors with aggressive clinical behavior.
  • Two patients developed recurrent, metastatic disease following nephrectomy.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis

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  • (PMID = 17199855.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Duplicate Publication; Journal Article
  • [Publication-country] Australia
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94. Katayama K, Hayashi T, Tsutahara K, Matsuoka A, Fujimoto N, Koide T: [Bilateral giant renal angiomyolipoma following hemodialysis in a patient with tuberous sclerosis]. Hinyokika Kiyo; 2009 Jun;55(6):335-8
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  • [Title] [Bilateral giant renal angiomyolipoma following hemodialysis in a patient with tuberous sclerosis].
  • She had been diagnosed with bilateral renal angiomyolipoma (AML) when she was 32 years old and had been on maintenance hemodialysis since the age of 44.
  • [MeSH-major] Angiomyolipoma / etiology. Kidney Neoplasms / etiology. Renal Dialysis. Tuberous Sclerosis / complications


95. Lesma E, Sirchia SM, Ancona S, Carelli S, Bosari S, Ghelma F, Montanari E, Di Giulio AM, Gorio A: The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells. Am J Pathol; 2009 Jun;174(6):2150-9
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  • [Title] The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells.
  • Tuberous sclerosis complex (TSC) is an autosomal-dominant disease that is caused by mutations in either the TSC1 or TSC2 gene.
  • Smooth muscle-like cells (ASMs) were isolated from an angiomyolipoma of a patient with TSC.
  • Our data show for the first time that methylation of the TSC2 promoter might cause a complete loss of tuberin in TSC2 cells, and that the pathogenesis of angiomyolipomas might also originate from epigenetic defects in smooth muscle cells.
  • [MeSH-major] Angiomyolipoma / genetics. Angiomyolipoma / pathology. DNA Methylation / genetics. Myocytes, Smooth Muscle / pathology. Tumor Suppressor Proteins / genetics

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  • (PMID = 19443708.001).
  • [ISSN] 1525-2191
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / Tumor Suppressor Proteins; 4JG2LF96VF / tuberous sclerosis complex 2 protein; W36ZG6FT64 / Sirolimus
  • [Other-IDs] NLM/ PMC2684180
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96. Corsenca A, Aebersold F, Moch H, Bird P, Weber M, Hofbauer G, Wüthrich RP, Serra AL: Combined nephrectomy and pre-emptive renal transplantation in a tuberous sclerosis patient with angiomyolipoma, renal carcinoma and life-threatening abdominal haemorrhages. Nephrol Dial Transplant; 2007 Nov;22(11):3330-3
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  • [Title] Combined nephrectomy and pre-emptive renal transplantation in a tuberous sclerosis patient with angiomyolipoma, renal carcinoma and life-threatening abdominal haemorrhages.
  • [MeSH-major] Angiomyolipoma / surgery. Hemorrhage / complications. Kidney Neoplasms / surgery. Kidney Transplantation. Nephrectomy. Tuberous Sclerosis / surgery


97. Setola SV, Catalano O, Sandomenico F, Siani A: Contrast-enhanced sonography of the kidney. Abdom Imaging; 2007 Jan-Feb;32(1):21-8
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  • There are several clinical scenarios where CEUS may play the role of a low-cost, scarcely invasive tool, including renal tumors (with special reference to small, indeterminate masses, i.e., differentiation between carcinoma and angiomyolipoma), renal atypical cystic masses (i.e., differentiation of malignant from benign cysts and follow-up of cystic lesions managed conservatively), renal infarction, renal infections, and renal injuries.
  • [MeSH-minor] Adult. Aged. Angiomyolipoma / ultrasonography. Carcinoma / ultrasonography. Catheter Ablation. Female. Humans. Infarction / ultrasonography. Kidney Diseases, Cystic / ultrasonography. Kidney Neoplasms / ultrasonography. Male. Microbubbles. Microcirculation / ultrasonography. Middle Aged. Phospholipids. Pyelonephritis / ultrasonography. Sulfur Hexafluoride. Ultrasonography, Doppler / methods. Ultrasonography, Interventional

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  • (PMID = 17420958.001).
  • [ISSN] 0942-8925
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Phospholipids; 0 / contrast agent BR1; WS7LR3I1D6 / Sulfur Hexafluoride
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98. Deng YF, Lin Q, Zhang SH, Ling YM, He JK, Chen XF: Malignant angiomyolipoma in the liver: a case report with pathological and molecular analysis. Pathol Res Pract; 2008;204(12):911-8
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  • [Title] Malignant angiomyolipoma in the liver: a case report with pathological and molecular analysis.
  • Malignant angiomyolipoma (AML) of the liver is rare.
  • [MeSH-major] Angiomyolipoma / genetics. Angiomyolipoma / pathology. Liver Neoplasms / genetics. Liver Neoplasms / pathology

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  • (PMID = 18723294.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / Tumor Suppressor Protein p53
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99. Yu W, Fraser RB, Gaskin DA, Fernandez CV, Wright JR Jr: C-Kit-positive metastatic malignant pigmented clear-cell epithelioid tumor arising from the kidney in a child without tuberous sclerosis. Ann Diagn Pathol; 2005 Dec;9(6):330-4
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  • The tumor was widely metastatic to the retroperitoneum and chest, and the patient died of the disease 9 months after diagnosis, despite active chemotherapy.
  • Pigmented epithelioid clear-cell tumor of the kidney is a rare variant of epithelioid angiomyolipoma and a member of the family of perivascular epithelioid cell tumors (PEComas).
  • The tumor demonstrated overlapping features between clear-cell sugar tumor and epithelioid variant of angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / metabolism. Kidney Neoplasms / metabolism. Proto-Oncogene Proteins c-kit / metabolism

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  • (PMID = 16308163.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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100. Zeng JP, Dong JH, Zhang WZ, Wang J, Pang XP: Hepatic angiomyolipoma: a clinical experience in diagnosis and treatment. Dig Dis Sci; 2010 Nov;55(11):3235-40
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  • [Title] Hepatic angiomyolipoma: a clinical experience in diagnosis and treatment.
  • BACKGROUND: Hepatic angiomyolipoma is a rare mesenchyme-derived neoplasm often misdiagnosed as hepatocellular carcinoma, and the treatment for it remains controversial.
  • AIMS: To develop the optimal preoperative diagnoses means and treatment modalities of hepatic angiomyolipoma.
  • RESULTS: Most hepatic angiomyolipoma were solitary.
  • CONCLUSIONS: Hepatic angiomyolipoma should be suspected in liver tumor patients with normal α-fetoprotein levels and no concomitant hepatitis.
  • [MeSH-major] Angiomyolipoma / diagnosis. Angiomyolipoma / surgery. Liver Neoplasms / diagnosis. Liver Neoplasms / surgery

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  • (PMID = 20165978.001).
  • [ISSN] 1573-2568
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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