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1. Turksoy O, Tokgoz H, Toparli S: Re: Radiological classification of renal angiomyolipomas based on 127 tumors. Int Braz J Urol; 2005 May-Jun;31(3):269
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  • [Title] Re: Radiological classification of renal angiomyolipomas based on 127 tumors.
  • [MeSH-major] Angiomyolipoma / radiography. Kidney Neoplasms / radiography

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  • [CommentOn] Int Braz J Urol. 2003 May-Jun;29(3):208-15; discussion 216 [15745523.001]
  • (PMID = 15992433.001).
  • [ISSN] 1677-5538
  • [Journal-full-title] International braz j urol : official journal of the Brazilian Society of Urology
  • [ISO-abbreviation] Int Braz J Urol
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Brazil
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2. Blick C, Ravindranath N, Muneer A, Jones A: Bilateral renal angiomyolipomas with invasion of the renal vein: a case report. ScientificWorldJournal; 2008;8:145-8
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  • [Title] Bilateral renal angiomyolipomas with invasion of the renal vein: a case report.
  • An angiomyolipoma (AML) is usually a benign, rare, and, more commonly, a unilateral renal tumour.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology. Renal Veins / pathology

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  • (PMID = 18264631.001).
  • [ISSN] 1537-744X
  • [Journal-full-title] TheScientificWorldJournal
  • [ISO-abbreviation] ScientificWorldJournal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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3. Robb VA, Astrinidis A, Henske EP: Frequent [corrected] hyperphosphorylation of ribosomal protein S6 [corrected] in lymphangioleiomyomatosis-associated angiomyolipomas. Mod Pathol; 2006 Jun;19(6):839-46
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  • [Title] Frequent [corrected] hyperphosphorylation of ribosomal protein S6 [corrected] in lymphangioleiomyomatosis-associated angiomyolipomas.
  • Lymphangioleiomyomatosis is a progressive lung disease characterized by a diffuse proliferation of pulmonary smooth muscle cells and cystic degeneration.
  • Lymphangioleiomyomatosis can occur either independently of other disease or in association with tuberous sclerosis complex, a tumor-suppressor gene syndrome caused by mutations that inactivate either TSC1 or TSC2.
  • TSC2 mutations and loss of heterozygosity have been identified in sporadic lymphangioleiomyomatosis-associated angiomyolipomas, thus implicating the TSC/Ras homolog-enriched in brain (Rheb)/mammalian target of Rapamycin (mTOR)/p70 S6 kinase signaling pathway in their pathogenesis.
  • This study was undertaken to determine whether the mTOR/p70 S6 kinase signaling pathway is activated in lymphangioleiomyomatosis-associated angiomyolipomas lacking TSC1/TSC2 loss of heterozygosity.
  • Phospho-ribosomal protein S6 (Ser235/236) immunohistochemistry was performed on five lymphangioleiomyomatosis-associated angiomyolipomas, two matched lymphangioleiomyomatosis pulmonary samples, and three sporadic angiomyolipomas.
  • TSC1/TSC2 loss of heterozygosity was previously excluded in these angiomyolipomas.
  • Moderate or strong phospho-ribosomal protein S6 immunoreactivity was found in all lymphangioleiomyomatosis-associated and sporadic angiomyolipomas, suggesting a high incidence of mTOR/p70 S6 kinase signaling pathway activation despite a lack of TSC1/TSC2 loss of heterozygosity.
  • Mutational analysis performed on DNA from these eight angiomyolipomas plus five additional sporadic angiomyolipomas did not reveal mutations in exons 3 and 4 (homologous sites of Ras activating mutations) of either Rheb or RhebL1.
  • These data suggest that activation of the Rheb/mTOR/p70 S6 kinase pathway is related to the pathogenesis of lymphangioleiomyomatosis-associated and sporadic angiomyolipomas lacking TSC1/TSC2 loss of heterozygosity.
  • This high incidence of mTOR signaling pathway activation suggests that treatment with mTOR inhibitors, such as Rapamycin, may benefit patients with angiomyolipomas independent of the detection of TSC1/TSC2 loss of heterozygosity.
  • [MeSH-major] Angiomyolipoma / metabolism. Lung Neoplasms / metabolism. Lymphangioleiomyomatosis / metabolism. Phosphatidylinositol 3-Kinases / metabolism. Protein Kinases / metabolism. Ribosomal Protein S6 / metabolism. Ribosomal Protein S6 Kinases, 70-kDa / metabolism

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  • [ErratumIn] Mod Pathol. 2006 Jun;19(6):889
  • (PMID = 16575396.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL 60746
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Neuropeptides; 0 / RHEB protein, human; 0 / RHEBL1 protein, human; 0 / Ribosomal Protein S6; EC 2.7.- / Protein Kinases; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.11.1 / Ribosomal Protein S6 Kinases, 70-kDa; EC 3.6.5.2 / Monomeric GTP-Binding Proteins; EC 3.6.5.2 / ras Proteins
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4. Li R, Zhang X, Hua X, Cai P, Zhong H, Guo Y, Ding S, Yan X: Real-time contrast-enhanced ultrasonography of resected and immunohistochemically proven hepatic angiomyolipomas. Abdom Imaging; 2010 Dec;35(6):676-82
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  • [Title] Real-time contrast-enhanced ultrasonography of resected and immunohistochemically proven hepatic angiomyolipomas.
  • PURPOSE: The purpose of this study was to assess real-time contrast-enhanced ultrasound in patients with hepatic angiomyolipomas with respect to contrast-enhancing kinetics and enhancement patterns.
  • All the 19 tumors were surgically resected and immunohistochemically proven sporadic hepatic angiomyolipomas.
  • CONCLUSION: Real-time contrast-enhanced ultrasonography can demonstrate typical imaging characteristics of hepatic angiomyolipomas in most cases, that is, inhomogeneous hyperenhancing pattern in arterial phase, prolonged hyperenhancement during portal and late phase with smooth and well-defined margin.
  • [MeSH-major] Angiomyolipoma / ultrasonography. Liver Neoplasms / ultrasonography

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  • (PMID = 20020286.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Contrast Media; 0 / Phospholipids; 0 / contrast agent BR1; 4419T9MX03 / Iohexol; 712BAC33MZ / iopromide; 84F6U3J2R6 / gadodiamide; K2I13DR72L / Gadolinium DTPA; WS7LR3I1D6 / Sulfur Hexafluoride
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5. Kulkarni B, Desai SB, Dave B, Tongaonkar HB, Kulkarni JN, Chinoy RF: Renal angiomyolipomas--a study of 18 cases. Indian J Pathol Microbiol; 2005 Oct;48(4):459-63
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  • [Title] Renal angiomyolipomas--a study of 18 cases.
  • Angiomyolipoma is a distinctive neoplasm composed of an intimate admixture of three components, viz. mature adipocytes, smooth muscle cells and blood vessels.
  • This study was undertaken to better define the various morphological patterns of angiomyolipoma and their immunohistochemical profile.
  • The paraffin blocks and slides of 18 cases of renal angiomyolipoma, accessioned over a period of 8 years from Tata Memorial Hospital, were reviewed.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Diseases / pathology

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  • (PMID = 16366094.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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6. Danforth TL, Lane BR, Novick AC: Conservative management of giant symptomatic angiomyolipomas in patients with the tuberous sclerosis complex. BJU Int; 2007 Oct;100(4):794-7
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  • [Title] Conservative management of giant symptomatic angiomyolipomas in patients with the tuberous sclerosis complex.
  • OBJECTIVE: To present two patients with the tuberous sclerosis complex in whom giant angiomyolipomas (AMLs) were managed conservatively for >20 years, as large (>4 cm) symptomatic AMLs are generally treated with embolization or nephrectomy because of the risks of haemorrhage.
  • CONCLUSION: Conservative management of AMLs can preserve renal function for >20 years in patients with tuberous sclerosis at high risk of end-stage renal disease.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy. Tuberous Sclerosis / complications

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  • (PMID = 17590180.001).
  • [ISSN] 1464-4096
  • [Journal-full-title] BJU international
  • [ISO-abbreviation] BJU Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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7. Kenerson H, Folpe AL, Takayama TK, Yeung RS: Activation of the mTOR pathway in sporadic angiomyolipomas and other perivascular epithelioid cell neoplasms. Hum Pathol; 2007 Sep;38(9):1361-71
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  • [Title] Activation of the mTOR pathway in sporadic angiomyolipomas and other perivascular epithelioid cell neoplasms.
  • Angiomyolipoma (AML) belong to a family of tumors known as perivascular epithelioid cell tumors (PEComas) that share a common immunophenotypic profile of muscle and melanocytic differentiation.
  • This suggests the possibility that mTOR inhibitors such as rapamycin may be therapeutic for this class of disease.

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  • (PMID = 17521703.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA102662-03; United States / NCI NIH HHS / CA / CA102662; United States / NCI NIH HHS / CA / CA077882-09; United States / NCI NIH HHS / CA / R01 CA102662-03; United States / NCI NIH HHS / CA / R01 CA102662; United States / NCI NIH HHS / CA / R01 CA077882-09; United States / NCI NIH HHS / CA / R01 CA077882
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein; EC 2.7.- / Protein Kinases; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.11.1 / Oncogene Protein v-akt; EC 2.7.11.1 / Ribosomal Protein S6 Kinases, 70-kDa; EC 3.1.3.67 / PTEN Phosphohydrolase
  • [Other-IDs] NLM/ NIHMS29653; NLM/ PMC2722219
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8. Dabbeche C, Chaker M, Chemali R, Perot V, El Hajj L, Ferriere JM, Ballanger P, Chabbert V, Cimpean A, Otal P, Huyghe E, Grenier N, Joffre F: [Role of embolization in renal angiomyolipomas]. J Radiol; 2006 Dec;87(12 Pt 1):1859-67
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  • [Title] [Role of embolization in renal angiomyolipomas].
  • OBJECTIVE: The purpose of this study is to present the role of embolization in the treatment of renal angiomyolipoma (AML) in cases of hemorrhage and to prevent bleeding.
  • [MeSH-major] Angiomyolipoma / complications. Embolization, Therapeutic. Hemorrhage / etiology. Hemorrhage / therapy. Kidney Neoplasms / complications

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  • (PMID = 17213770.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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9. Ishibashi N, Mochizuki T, Tanaka H, Okada Y, Kobayashi M, Takahashi M: A case of lipiduria after arterial embolization for renal angiomyolipomas. Cardiovasc Intervent Radiol; 2010 Jun;33(3):615-8
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  • [Title] A case of lipiduria after arterial embolization for renal angiomyolipomas.
  • We report the case of a 31-year-old woman who suffered lipiduria after selective transcatheter arterial embolization for renal angiomyolipoma (AML).
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy. Lipids / urine

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  • (PMID = 20087737.001).
  • [ISSN] 1432-086X
  • [Journal-full-title] Cardiovascular and interventional radiology
  • [ISO-abbreviation] Cardiovasc Intervent Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lipids
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10. Hadley DA, Bryant LJ, Ruckle HC: Conservative treatment of renal angiomyolipomas in patients with tuberous sclerosis. Clin Nephrol; 2006 Jan;65(1):22-7
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  • [Title] Conservative treatment of renal angiomyolipomas in patients with tuberous sclerosis.
  • AIMS: Renal angiomyolipoma (AML) associated with tuberous sclerosis (TS) presents a treatment dilemma due to multifocal tumors with a potential for significant growth and subsequent hemorrhage.
  • Of the 8 patients, 6 received treatment during the course of their disease, including arterial embolization of 7 renal units in 5 symptomatic patients (2 patients needed 2 embolizations).
  • [MeSH-major] Angiomyolipoma / therapy. Kidney Neoplasms / therapy. Tuberous Sclerosis / complications

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  • (PMID = 16429838.001).
  • [ISSN] 0301-0430
  • [Journal-full-title] Clinical nephrology
  • [ISO-abbreviation] Clin. Nephrol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Analgesics; AYI8EX34EU / Creatinine
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11. Engels K, Stauber R, Magnussen H, Kirsten D, Watz H, Wirtz H: Angiomyolipomas are indicator lesions for sporadic lymphangioleiomyomatosis in women. Eur Urol; 2009 Mar;55(3):755-6
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  • [Title] Angiomyolipomas are indicator lesions for sporadic lymphangioleiomyomatosis in women.
  • [MeSH-major] Angiomyolipoma / complications. Kidney Neoplasms / complications. Lung Neoplasms / complications. Lung Neoplasms / diagnosis. Lymphangioleiomyomatosis / complications. Lymphangioleiomyomatosis / diagnosis

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  • (PMID = 18835088.001).
  • [ISSN] 1873-7560
  • [Journal-full-title] European urology
  • [ISO-abbreviation] Eur. Urol.
  • [Language] eng
  • [Publication-type] Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
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12. Johnson SC, Graham S, D'Agostino H, Elmajian DA, Shingleton WB: Percutaneous renal cryoablation of angiomyolipomas in patients with solitary kidneys. Urology; 2009 Dec;74(6):1246-9
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  • [Title] Percutaneous renal cryoablation of angiomyolipomas in patients with solitary kidneys.
  • OBJECTIVES: To determine the feasibility and safety of performing percutaneous cryoablation of angiomyolipomas (AMLs) in patients with solitary kidneys.
  • [MeSH-major] Angiomyolipoma / surgery. Cryosurgery. Kidney Neoplasms / surgery. Nephrectomy / methods

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  • (PMID = 19815260.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Lim SD, Kim W, Ahn G, Kwon GY: Protein expression and mutational analysis of epidermal growth factor receptor in renal angiomyolipomas. Pathol Int; 2007 Sep;57(9):584-8
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  • [Title] Protein expression and mutational analysis of epidermal growth factor receptor in renal angiomyolipomas.
  • Renal angiomyolipoma (AML) is a benign but progressive tumor that occasionally requires non-surgical therapy and there appears to be a possibility that epidermal growth factor (EGF) is associated with pathogenesis of renal AML.
  • [MeSH-major] Angiomyolipoma / genetics. DNA Mutational Analysis. Kidney Neoplasms / genetics. Mutation. Receptor, Epidermal Growth Factor / genetics

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  • (PMID = 17685929.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / DNA, Neoplasm; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
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14. Shi H, Cao D, Wei L, Sun L, Guo A: Inflammatory angiomyolipomas of the liver: a clinicopathologic and immunohistochemical analysis of 5 cases. Ann Diagn Pathol; 2010 Aug;14(4):240-6
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  • [Title] Inflammatory angiomyolipomas of the liver: a clinicopathologic and immunohistochemical analysis of 5 cases.
  • Hepatic angiomyolipoma (AML) may demonstrate a marked histologic diversity.
  • All patients showed no evidence of disease after the initial surgical excision during a follow-up period from 3 to 9 years.
  • [MeSH-major] Angiomyolipoma / pathology. Liver Neoplasms / pathology

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20637427.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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15. Kang M, Khandelwal N, Lal A, Singhal M, Mete U, Mandal AK: CT angiography in renal angiomyolipomas. Abdom Imaging; 2007 Nov;32(6):772-4
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  • [Title] CT angiography in renal angiomyolipomas.
  • Renal angiomyolipomas are fat containing tumours, which are associated with a strong risk of hemorrhage due to the presence of abnormal vessels and pseudoaneurysms.
  • We present three cases of ruptured renal angiomyolipomas with multiple or large pseudoaneurysms diagnosed by CT angiography which enabled emergent endovascular intervention; and propose CT angiography as the diagnostic modality of choice, particularly in emergency situations.
  • [MeSH-major] Angiomyolipoma / radiography. Kidney Neoplasms / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 17285401.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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16. Tsai CK, Lin YT, Lin TC: Traumatic rupture of bilateral huge renal angiomyolipomas in tuberous sclerosis complex. J Trauma; 2010 Aug;69(2):477
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  • [Title] Traumatic rupture of bilateral huge renal angiomyolipomas in tuberous sclerosis complex.

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  • (PMID = 20699763.001).
  • [ISSN] 1529-8809
  • [Journal-full-title] The Journal of trauma
  • [ISO-abbreviation] J Trauma
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Baños Madrid R, Garre Sánchez MC, Morán Sánchez S: [Patient with tuberous sclerosis and giant renal angiomyolipomas]. An Med Interna; 2005 Oct;22(10):500-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Patient with tuberous sclerosis and giant renal angiomyolipomas].
  • [MeSH-major] Angiomyolipoma / complications. Kidney Neoplasms / complications. Tuberous Sclerosis / complications

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  • [CommentOn] An Med Interna. 2004 Sep;21(9):469 [15476434.001]
  • (PMID = 16411306.001).
  • [ISSN] 0212-7199
  • [Journal-full-title] Anales de medicina interna (Madrid, Spain : 1984)
  • [ISO-abbreviation] An Med Interna
  • [Language] spa
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Spain
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18. Sukumar S, Balagopal Nair T, Mohammed Saheed CS, Sanjay Bhat H: Bilateral nephron sparing surgeries for multiple renal angiomyolipomas in Bourneville's disease. Int Urol Nephrol; 2007;39(2):389-91
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  • [Title] Bilateral nephron sparing surgeries for multiple renal angiomyolipomas in Bourneville's disease.
  • INTRODUCTION: Angiomyolipomas are the most common renal lesions in tuberous sclerosis complex.
  • CASE-HISTORY: A 22-year-old lady with bilateral multiple large symptomatic renal angiomyolipomas associated with other manifestations of tuberous sclerosis was managed with partial nephrectomies on either side.
  • DISCUSSION: Intervention for renal angiomyolipomas is indicated in symptomatic tumors larger than four centimetres.
  • Nephron sparing surgery of both kidneys for angiomyolipomas in association with tuberous sclerosis has only been sparingly reported in literature.
  • [MeSH-major] Angiomyolipoma / surgery. Kidney Neoplasms / surgery. Nephrectomy / methods. Tuberous Sclerosis / complications

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  • [Cites] J Urol. 2004 Jan;171(1):102-5 [14665854.001]
  • [Cites] Int J Urol. 2002 Feb;9(2):117-9 [12028304.001]
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  • [Cites] J Urol. 1986 Jun;135(6):1121-4 [3520013.001]
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  • (PMID = 17004032.001).
  • [ISSN] 0301-1623
  • [Journal-full-title] International urology and nephrology
  • [ISO-abbreviation] Int Urol Nephrol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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19. Ozkara H, Ozkan B, Solok V: Management of renal abscess formation after embolization due to renal angiomyolipomas in two cases. Int Urol Nephrol; 2006;38(3-4):427-9
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  • [Title] Management of renal abscess formation after embolization due to renal angiomyolipomas in two cases.
  • Current management strategies of renal angiomyolipomas (AMLs) include observation, embolization and partial or total nephrectomy.
  • Selective arterial embolization is an effective and safe treatment of large angiomyolipomas with low complication rates.
  • [MeSH-major] Abscess / etiology. Abscess / therapy. Angiomyolipoma / complications. Angiomyolipoma / therapy. Embolization, Therapeutic / adverse effects. Kidney Diseases / etiology. Kidney Diseases / therapy. Kidney Neoplasms / complications. Kidney Neoplasms / therapy. Staphylococcal Infections / etiology. Staphylococcal Infections / therapy

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  • [Cites] Eur J Radiol. 1999 Dec;32(3):153-9 [10632551.001]
  • [Cites] J Urol. 2002 Oct;168(4 Pt 1):1315-25 [12352384.001]
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  • (PMID = 17115299.001).
  • [ISSN] 0301-1623
  • [Journal-full-title] International urology and nephrology
  • [ISO-abbreviation] Int Urol Nephrol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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20. Williams TR, Oakes MF: Metastatic breast carcinoma to renal angiomyolipomas in tuberous sclerosis. Urology; 2008 Feb;71(2):352.e5-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic breast carcinoma to renal angiomyolipomas in tuberous sclerosis.
  • Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disease manifesting as hamartomatous involvement of several organs, including brain, kidneys, skin, heart, lungs, and retina.
  • We report the first case of a patient with TSC, with large bilateral renal angiomyolipomas (AML), who developed multiple soft tissue masses within her primarily fatty AMLs, resulting from metastatic breast cancer.
  • [MeSH-major] Angiomyolipoma / complications. Angiomyolipoma / pathology. Breast Neoplasms / complications. Breast Neoplasms / pathology. Kidney Neoplasms / complications. Kidney Neoplasms / secondary. Tuberous Sclerosis / complications

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  • (PMID = 18308125.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 6
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21. Chang YH, Wang LJ, Chuang CK, Wong YC, Wu CT, Hsieh ML: The efficacy and outcomes of urgent superselective transcatheter arterial embolization of patients with ruptured renal angiomyolipomas. J Trauma; 2007 Jun;62(6):1487-90
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  • [Title] The efficacy and outcomes of urgent superselective transcatheter arterial embolization of patients with ruptured renal angiomyolipomas.
  • BACKGROUND: To assess the efficacy and outcomes of urgent superselective transcatheter arterial embolization for emergency patients with ruptured renal angiomyolipomas.
  • METHODS: During a 49-month period, all emergency patients with ruptured angiomyolipomas that underwent urgent superselective transcatheter arterial embolization within the first 24 hours of admission were enrolled in this study.
  • RESULTS: The sample population consisted of seven female patients with ruptured angiomyolipomas; mean age was 48 years.
  • CONCLUSIONS: Urgent superselective transcatheter arterial embolization was an effective treatment for our sample of emergency patients with ruptured renal angiomyolipomas where conservative supportive treatments had failed.
  • [MeSH-major] Angiomyolipoma / complications. Embolization, Therapeutic / methods. Hemorrhage / therapy. Kidney Neoplasms / complications

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  • [ErratumIn] J Trauma. 2007 Nov;63(5):1190
  • (PMID = 17563671.001).
  • [ISSN] 1529-8809
  • [Journal-full-title] The Journal of trauma
  • [ISO-abbreviation] J Trauma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Jinzaki M, Silverman SG, Tanimoto A, Shinmoto H, Kuribayashi S: Angiomyolipomas that do not contain fat attenuation at unenhanced CT. Radiology; 2005 Jan;234(1):311; author reply 311-2
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  • [Title] Angiomyolipomas that do not contain fat attenuation at unenhanced CT.
  • [MeSH-major] Angiomyolipoma / radiography. Carcinoma, Renal Cell / radiography. Image Enhancement / methods. Iohexol / analogs & derivatives. Kidney Neoplasms / radiography. Tomography, X-Ray Computed / methods

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  • [CommentOn] Radiology. 2004 Mar;230(3):677-84 [14990834.001]
  • (PMID = 15618388.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 4419T9MX03 / Iohexol; 712BAC33MZ / iopromide
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23. Lai HY, Chen CK, Lee YH, Tsai PP, Chen JH, Shen WC: Multicentric aggressive angiomyolipomas: a rare form of PEComas. AJR Am J Roentgenol; 2006 Mar;186(3):837-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multicentric aggressive angiomyolipomas: a rare form of PEComas.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Spinal Neoplasms / diagnosis

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  • (PMID = 16498117.001).
  • [ISSN] 0361-803X
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Roma AA, Magi-Galluzzi C, Zhou M: Differential expression of melanocytic markers in myoid, lipomatous, and vascular components of renal angiomyolipomas. Arch Pathol Lab Med; 2007 Jan;131(1):122-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential expression of melanocytic markers in myoid, lipomatous, and vascular components of renal angiomyolipomas.
  • CONTEXT: Renal angiomyolipoma is a tumor composed of varying amounts of fat, smooth muscle, and blood vessels.
  • OBJECTIVES: To compare the sensitivities of 5 melanocytic markers in renal angiomyolipoma and to study the expression patterns of these markers in the 3 different components of angiomyolipoma.
  • DESIGN: A tissue microarray of 20 renal angiomyolipomas was constructed.
  • CONCLUSIONS: HMB-45 and Melan-A combined were positive in 100% of the renal angiomyolipomas.
  • [MeSH-major] Angiomyolipoma / metabolism. Antigens, Neoplasm / metabolism. Kidney Neoplasms / metabolism. Melanocytes / metabolism. Neoplasm Proteins / metabolism

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  • (PMID = 17227112.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; EC 1.14.18.1 / Monophenol Monooxygenase; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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25. Tillou X, Boutemy F, Remond A, Petit J: [Contribution of curative and preventive embolization for renal angiomyolipomas treatment]. Prog Urol; 2010 Oct;20(9):627-32
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  • [Title] [Contribution of curative and preventive embolization for renal angiomyolipomas treatment].
  • OBJECTIVE: The purpose of this study was to present the role of embolization in the treatment of kidney angiomyolipomas (AML), for preventive care or in case of bleeding.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic. Kidney Neoplasms / therapy

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20951930.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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26. Matuszewski M, Michajłowski J, Bianek-Bodzak A, Krajka K: Radiofrequency ablation of small symptomatic angiomyolipomas of the kidney: Report of two cases. Pol J Radiol; 2010 Jul;75(3):68-71

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiofrequency ablation of small symptomatic angiomyolipomas of the kidney: Report of two cases.
  • Approximately 2-3% of these lesions are proved to be angiomyolipomas (AML).

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  • [Cites] AJR Am J Roentgenol. 1988 Sep;151(3):497-501 [3044036.001]
  • [Cites] J Urol. 1986 Jun;135(6):1121-4 [3520013.001]
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  • (PMID = 22802796.001).
  • [ISSN] 1733-134X
  • [Journal-full-title] Polish journal of radiology
  • [ISO-abbreviation] Pol J Radiol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Other-IDs] NLM/ PMC3389883
  • [Keywords] NOTNLM ; RFA / angiomyolipoma of the kidney / minimally invasive treatment
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27. Dumortier J, Guillaud O, Walter T, Ber CE, Partensky C, Boillot O, Scoazec JY: Liver transplantation for multiple angiomyolipomas complicating tuberous sclerosis complex. Gastroenterol Clin Biol; 2010 Sep;34(8-9):494-8
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  • [Title] Liver transplantation for multiple angiomyolipomas complicating tuberous sclerosis complex.
  • Hepatic multiple, bilateral angiomyolipomas are a rare and usually asymptomatic complication in patients with tuberous sclerosis.
  • We report here the case of a patient who needed liver transplantation because of debilitating manifestations and mechanical complications of massive liver involvement by multiple angiomyolipomas (severe malnutrition, anorexia and abdominal pain).
  • [MeSH-major] Angiomyolipoma / surgery. Liver Neoplasms / surgery. Liver Transplantation. Neoplasms, Multiple Primary / surgery. Tuberous Sclerosis / complications


28. Rimon U, Duvdevani M, Garniek A, Golan G, Bensaid P, Ramon J, Morag B: Large renal angiomyolipomas: digital subtraction angiographic grading and presentation with bleeding. Clin Radiol; 2006 Jun;61(6):520-6
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  • [Title] Large renal angiomyolipomas: digital subtraction angiographic grading and presentation with bleeding.
  • MATERIALS AND METHODS: Thirty patients with 35 renal angiomyolipomas (size range 4-20 cm, mean 9.9 cm) underwent both digital subtraction angiography (DSA) and computed tomography (CT).
  • CONCLUSIONS: According to our criteria, large angiomyolipomas with minimal vascularity are less likely to bleed, and do not need prophylactic treatment.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology

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  • (PMID = 16713423.001).
  • [ISSN] 0009-9260
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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29. Ewalt DH, Diamond N, Rees C, Sparagana SP, Delgado M, Batchelor L, Roach ES: Long-term outcome of transcatheter embolization of renal angiomyolipomas due to tuberous sclerosis complex. J Urol; 2005 Nov;174(5):1764-6
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  • [Title] Long-term outcome of transcatheter embolization of renal angiomyolipomas due to tuberous sclerosis complex.
  • PURPOSE: Complications from renal angiomyolipomas (AMLs) are common in patients with tuberous sclerosis complex (TSC) and tumors greater than 4 cm are more likely to cause symptoms.

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  • (PMID = 16217279.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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30. Lee SY, Hsu HH, Chen YC, Huang CC, Wong YC, Wang LJ, Chuang CK, Yang CW: Embolization of renal angiomyolipomas: short-term and long-term outcomes, complications, and tumor shrinkage. Cardiovasc Intervent Radiol; 2009 Nov;32(6):1171-8
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  • [Title] Embolization of renal angiomyolipomas: short-term and long-term outcomes, complications, and tumor shrinkage.
  • This study retrospectively evaluated outcomes, complications, and tumor shrinkage in renal angiomyolipomas after transcatheter arterial embolization (TAE).
  • All renal angiomyolipoma patients who underwent TAE between August 2000 and December 2008 and had short-term (<or=6 months) or long-term (>6 months) follow-up images were evaluated.
  • Eleven renal angiomyolipoma patients who had undergone TAE were included.
  • In conclusion, selective TAE is effective for tumor shrinkage in most renal angiomyolipomas, with acceptable complication and relapse rates.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy

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  • (PMID = 19572171.001).
  • [ISSN] 1432-086X
  • [Journal-full-title] Cardiovascular and interventional radiology
  • [ISO-abbreviation] Cardiovasc Intervent Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Habib SL: Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. Mol Cancer; 2009;8:13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients.
  • TSC-2 gene encodes tuberin, a protein involved in the pathogenesis of kidney tumors, both angiomyolipomas and renal cell carcinomas.
  • RESULTS: Kidney angiomyolipoma tissue from TSC patients expresses significant levels of phopho-tuberin and low levels of tuberin compared to control kidney tissue.
  • CONCLUSION: These data indicate that tuberin deficiency in angiomyolipoma enhances mTOR activation by phosphorylation of S6K and downregulation of protein and mRNA expression of OGG1 resulted in accumulation of oxidized DNA in patients with TSC.
  • These data suggest that tuberin and OGG1 are important proteins in the pathogenesis of angiomyolipoma in TSC patients.
  • [MeSH-major] Angiomyolipoma / genetics. Angiomyolipoma / metabolism. DNA Damage / physiology. DNA Glycosylases / metabolism. Tuberous Sclerosis / genetics. Tuberous Sclerosis / metabolism

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  • (PMID = 19265534.001).
  • [ISSN] 1476-4598
  • [Journal-full-title] Molecular cancer
  • [ISO-abbreviation] Mol. Cancer
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / P50 DK061597
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CCAAT-Binding Factor; 0 / NFYA protein, human; 0 / Tumor Suppressor Proteins; 136601-57-5 / Cyclin D1; 4JG2LF96VF / tuberous sclerosis complex 2 protein; 88847-89-6 / 8-oxo-7-hydrodeoxyguanosine; EC 2.7.- / Protein Kinases; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.1.1 / mTOR protein, mouse; EC 3.2.2.- / DNA Glycosylases; EC 3.2.2.- / oxoguanine glycosylase 1, human; G9481N71RO / Deoxyguanosine
  • [Other-IDs] NLM/ PMC2657104
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32. Majid S, White D, Sarkar S: An unusual cause for the incidental finding of multiple liver lesions. Diagnosis: multiple fatty vascular lesions of angiomyolipomas. Gut; 2006 Jul;55(7):983, 1029
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  • [Title] An unusual cause for the incidental finding of multiple liver lesions. Diagnosis: multiple fatty vascular lesions of angiomyolipomas.
  • [MeSH-major] Angiomyolipoma / radiography. Fatty Liver / radiography. Liver / radiography. Liver Neoplasms / radiography

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  • (PMID = 16766752.001).
  • [ISSN] 0017-5749
  • [Journal-full-title] Gut
  • [ISO-abbreviation] Gut
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1856355
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33. Kawauchi S, Nawata H, Yamagata Y, Yaegashi H, Fukunaga M, Moriya T, Furuya T, Sugino N, Sasaki K: Chromosomal imbalances detected by comparative genomic hybridization provide evidence that HMB-45-negative uterine angiomyolipomas belong to the PEComa family. Histopathology; 2010 Jun;56(7):974-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chromosomal imbalances detected by comparative genomic hybridization provide evidence that HMB-45-negative uterine angiomyolipomas belong to the PEComa family.
  • [MeSH-major] Angiomyolipoma / genetics. Antigens, Neoplasm / genetics. Chromosome Aberrations. Neoplasm Proteins / genetics. Perivascular Epithelioid Cell Neoplasms / genetics. Uterine Neoplasms / genetics

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  • (PMID = 20636800.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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34. Taviloglu K, Yanar H, Dilege E, Poyanli A, Zorba O, Ertekin C, Guloglu R, Dursun M: Non-traumatic kidney rupture in a tuberosclerosis patient with renal angiomyolipomas. Intern Med J; 2007 Jul;37(7):504-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-traumatic kidney rupture in a tuberosclerosis patient with renal angiomyolipomas.
  • [MeSH-major] Angiomyolipoma / complications. Kidney Diseases / complications. Kidney Neoplasms / complications. Tuberous Sclerosis / complications

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  • (PMID = 17547731.001).
  • [ISSN] 1445-5994
  • [Journal-full-title] Internal medicine journal
  • [ISO-abbreviation] Intern Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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35. Krischock L, Beach R, Taylor J: Sirolimus and tuberous sclerosis-associated renal angiomyolipomas. Arch Dis Child; 2010 May;95(5):391-2
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sirolimus and tuberous sclerosis-associated renal angiomyolipomas.
  • Tuberous sclerosis, caused by germline mutations in the TSC1 or TSC2 genes, is associated with aberrant upregulation of the mammalian target of rapamycin (mTOR) signalling pathway, resulting in growth of tumours, including renal angiomyolipomas (AMLs).
  • [MeSH-major] Angiomyolipoma / drug therapy. Antibiotics, Antineoplastic / therapeutic use. Kidney Neoplasms / drug therapy. Sirolimus / therapeutic use. Tuberous Sclerosis / complications

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  • (PMID = 20457704.001).
  • [ISSN] 1468-2044
  • [Journal-full-title] Archives of disease in childhood
  • [ISO-abbreviation] Arch. Dis. Child.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; W36ZG6FT64 / Sirolimus
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36. Sánchez-Estella J, Bordel-Gómez MT, Zamora-Martínez T: [Presentation of 2 new cases of cutaneous angiomyolipomas and literature review]. Actas Dermosifiliogr; 2009 Nov;100(9):808-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Presentation of 2 new cases of cutaneous angiomyolipomas and literature review].
  • We present 2 new cases of cutaneous angiomyolipomas with very similar characteristics, located in the postauricular region of 2 women aged 58 and 52 years.
  • In contrast to renal angiomyolipomas, which are often associated with tuberous sclerosis, these angiomyolipomas were negative for melanocytic immunohistochemical markers (human melanoma black-45 antigen and melanoma antigen recognized by T cells 1).
  • The relationship of these tumors with angioleiomyomas and renal angiomyolipomas is discussed.
  • [MeSH-major] Angiomyolipoma / pathology. Ear Neoplasms / pathology. Ear, External / pathology. Skin Neoplasms / pathology

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  • (PMID = 19889303.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Cytoskeletal Proteins; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
  • [Number-of-references] 21
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37. Beer TW: Cutaneous angiomyolipomas are HMB45 negative, not associated with tuberous sclerosis, and should be considered as angioleiomyomas with fat. Am J Dermatopathol; 2005 Oct;27(5):418-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous angiomyolipomas are HMB45 negative, not associated with tuberous sclerosis, and should be considered as angioleiomyomas with fat.
  • Angiomyolipomas are uncommon tumors in the skin.
  • Three cases of cutaneous angiomyolipoma are reported, which were all HMB45 negative and not associated with tuberous sclerosis.
  • The author proposes that cutaneous angiomyolipomas should be termed angioleiomyoma with fat to avoid confusion with unrelated non-cutaneous angiomyolipomas that are HMB45 negative and require investigation for tuberous sclerosis.
  • [MeSH-major] Angiomyolipoma / classification. Angiomyolipoma / pathology. Angiomyoma / pathology. Neoplasm Proteins / biosynthesis. Skin Neoplasms / classification. Skin Neoplasms / pathology

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  • (PMID = 16148412.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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38. Low SC, Peh WC, Muttarak M, Cheung HS, Ng IO: Imaging features of hepatic angiomyolipomas. J Med Imaging Radiat Oncol; 2008 Apr;52(2):118-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Imaging features of hepatic angiomyolipomas.
  • We review the imaging appearances of hepatic angiomyolipomas in patients with and without tuberous sclerosis.
  • Sporadic hepatic angiomyolipomas have a varied appearance because of the inconstant proportion of fat, making confident imaging diagnosis difficult and necessitating biopsy in many cases.
  • In patients with tuberous sclerosis, hepatic angiomyolipomas have a more consistent imaging appearance and, together with other features of the syndrome, can be more easily diagnosed.
  • [MeSH-major] Angiomyolipoma / diagnosis. Liver Neoplasms / diagnosis. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 18373801.001).
  • [ISSN] 1754-9485
  • [Journal-full-title] Journal of medical imaging and radiation oncology
  • [ISO-abbreviation] J Med Imaging Radiat Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Australia
  • [Number-of-references] 10
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39. Wong IY, Shortliffe LD: The management of renal angiomyolipomas in a patient with tuberous sclerosis. Nat Clin Pract Urol; 2009 Mar;6(3):168-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The management of renal angiomyolipomas in a patient with tuberous sclerosis.
  • DIAGNOSIS: Bilateral angiomyolipomas.Management Observation, serial imaging, embolization and infarction.
  • [MeSH-major] Angiomyolipoma / therapy. Kidney Neoplasms / therapy. Tuberous Sclerosis / therapy
  • [MeSH-minor] Adolescent. Disease Management. Embolization, Therapeutic / methods. Female. Humans

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  • (PMID = 19265859.001).
  • [ISSN] 1743-4289
  • [Journal-full-title] Nature clinical practice. Urology
  • [ISO-abbreviation] Nat Clin Pract Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Bonsib SM, Moghadamfalahi M, Bhalodia A: Lymphatic differentiation in renal angiomyolipomas. Hum Pathol; 2009 Mar;40(3):374-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphatic differentiation in renal angiomyolipomas.
  • Renal angiomyolipomas are mesenchymal neoplasms with varying proportions of smooth muscle, adipose tissue, and abnormal blood vessels.
  • Although the presence of lymphangiomatous-like foci is frequently noted in large series of angiomyolipoma, lymphatic differentiation has not been previously studied.
  • Twelve angiomyolipomas from 10 patients were identified.
  • The angiomyolipomas ranged from typical triphasic tumors to leiomyoma-like and lipoma-like tumors.
  • It was most prevalent in myoid areas of the triphasic angiomyolipomas and in the leiomyoma-like variant, but infrequent and widely scattered within the adipose regions of triphasic angiomyolipoma and in the lipoma-like variant.
  • In conclusion, lymphatic differentiation is common in angiomyolipomas, preferentially located in myoid regions.
  • These data expand the mesenchymal pluripotential profile of renal angiomyolipomas.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology. Lymphatic Vessels / pathology

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  • (PMID = 18973924.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Biomarkers, Tumor; 0 / Membrane Glycoproteins; 0 / PDPN protein, human; 0 / monoclonal antibody D2-40
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41. Illescas Molina T, Montalvo Montes J, Contreras Cecilia E, Muñoz Muñiz Mdel M, González González A, Herraiz Martínez MA: [Angiomyolipomas, tuberous sclerosis and pregnancy]. Ginecol Obstet Mex; 2009 Aug;77(8):380-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiomyolipomas, tuberous sclerosis and pregnancy].
  • Renal angiomyolipomas are uncommon tumours during pregnancy, but it's important to consider them in the differential diagnosis, for the increased risk of complications such as bleeding, specially during pregnancy.
  • To show both possibilities, we describe two cases of pregnant women with angiomyolipomas: the first one presented with bleeding of the tumour (Wünderlich's syndrome), but surveillance without treatment was possible until 37th week of gestation, and embolization of the tumour was performed afterwards.
  • The second patient had multiple well known angiomyolipomas, associated to tuberous sclerosis; even though she had required two previous embolizations, she had an uneventful pregnancy, without any episodes of bleeding.
  • Since there are few papers available in the literature, there is not an agreement about therapeutic management when pregnant women present with bleeding angiomyolipomas (Wünderlich's syndrome).
  • [MeSH-major] Angiomyolipoma / complications. Kidney Neoplasms / complications. Pregnancy Complications, Neoplastic. Tuberous Sclerosis / complications


42. Nasir K, Ahmad A: Giant renal angiomyolipomas and pulmonary lymphangiomyomatosis. Saudi J Kidney Dis Transpl; 2010 Mar;21(2):314-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant renal angiomyolipomas and pulmonary lymphangiomyomatosis.
  • Renal angiomyolipomas (AML) are benign tumors, which can acquire huge size and when bilateral, they are diagnostic of tuberous sclerosis (TS).
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Lung Neoplasms / diagnosis. Lymphangioleiomyomatosis / diagnosis. Neoplasms, Multiple Primary. Tuberous Sclerosis / diagnosis

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  • (PMID = 20228520.001).
  • [ISSN] 1319-2442
  • [Journal-full-title] Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
  • [ISO-abbreviation] Saudi J Kidney Dis Transpl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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43. Francesca F, Pomara G, Campo G, Casale P: Elective open nephron-sparing surgery for renal masses: Single-center experience with 223 consecutive patients. J Clin Oncol; 2009 May 20;27(15_suppl):e16139

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Renal cell carcinoma was present in 177 patients (76.6%), benign renal masses were diagnosed in in 54 pazienti (23.3%): angiomyolipoma (35%), oncocytoma (40%), complicated cyst (25%).

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  • (PMID = 27963354.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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44. Yang B, Chen WH, Shi PZ, Xiang JJ, Xu RJ, Liu JH: Coincidence of hepatocelluar carcinoma and hepatic angiomyolipomas in tuberous sclerosis complex: a case report. World J Gastroenterol; 2008 Feb 7;14(5):812-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coincidence of hepatocelluar carcinoma and hepatic angiomyolipomas in tuberous sclerosis complex: a case report.
  • Unlike the common development of renal angiomyolipoma, hepatic angiomyolipoma rarely occur in patients with TSC.
  • We report here a patient with hepatic angiomyolipomas and concurrent hepatocellular carcinoma in TSC.
  • In this patient, multiple hepatic angiomyolipomas were diagnosed with recognition of their fat components and typical clinical settings.
  • In such clinical settings, fat containing lesions in liver can be reasonably treated as angiomyolipomas, but non fat containing lesions must be differentiated from hepatocellular carcinoma, imaging guided biopsy can be adopted to confirm the diagnosis.
  • [MeSH-major] Angiomyolipoma / pathology. Carcinoma, Hepatocellular / pathology. Liver Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Tuberous Sclerosis / pathology

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  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
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45. Herry I, Neukirch C, Debray MP, Mignon F, Crestani B: Dramatic effect of sirolimus on renal angiomyolipomas in a patient with tuberous sclerosis complex. Eur J Intern Med; 2007 Jan;18(1):76-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dramatic effect of sirolimus on renal angiomyolipomas in a patient with tuberous sclerosis complex.
  • Angiomyolipomas are very common in patients with tuberous sclerosis complex (TSC) and cause substantial morbidity.

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  • (PMID = 17223050.001).
  • [ISSN] 0953-6205
  • [Journal-full-title] European journal of internal medicine
  • [ISO-abbreviation] Eur. J. Intern. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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46. Warth A, Herpel E, Schmähl A, Hoffmann H, Herth FJ, Schirmacher P, Dienemann H, Schnabel PA: Mediastinal angiomyolipomas in a male patient affected by tuberous sclerosis. Eur Respir J; 2008 Mar;31(3):678-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mediastinal angiomyolipomas in a male patient affected by tuberous sclerosis.
  • Classical angiomyolipomas are benign tumours composed of various tissues, including components of fat, abnormal blood vessels and smooth muscle cells.
  • The present study reports a male patient affected by TSC with intermittent, massive chylous pleural effusions, who developed recurrent mediastinal angiomyolipomas.
  • Although angiomyolipomas frequently occur in the kidneys of TSC patients, this case is the first report of mediastinal angiomyolipomas associated with TSC.
  • [MeSH-major] Angiomyolipoma / complications. Dyspnea / etiology. Mediastinal Neoplasms / complications. Neoplasm Recurrence, Local / complications. Tuberous Sclerosis / complications


47. Bierer S, Wülfing C, Bode ME, Pühse G, Brinkmann OA, Hertle L: [Bilateral renal angiomyolipomas with a thrombus in the inferior caval vein. Rare growth pattern of a benign tumor]. Urologe A; 2005 Dec;44(12):1469-72
MedlinePlus Health Information. consumer health - Kidney Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Bilateral renal angiomyolipomas with a thrombus in the inferior caval vein. Rare growth pattern of a benign tumor].
  • [Transliterated title] Bilaterale renale Angiomyolipome mit Thrombus in der Vena cava inferior. Seltenes Wachstumsverhalten eines benignen Tumors.
  • Renal angiomyolipomas are mesenchymal tumors that are composed of fat tissue, smooth muscle cells and vessels.
  • We report a new case of bilateral renal angiomyolipomas with a caval thrombus in a 36 year old female patient with tuberous sclerosis, and give a brief review of the related literature.
  • [MeSH-major] Angiomyolipoma / complications. Angiomyolipoma / diagnosis. Kidney Neoplasms / complications. Kidney Neoplasms / diagnosis. Vena Cava, Inferior / pathology. Venous Thrombosis / diagnosis. Venous Thrombosis / etiology

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  • (PMID = 16133230.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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48. Ciftci AO, Sanlialp I, Tanyel FC, Buyukpamukçu N: The association of pulmonary lymphangioleiomyomatosis with renal and hepatic angiomyolipomas in a prepubertal girl: a previously unreported entity. Respiration; 2007;74(3):335-7
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  • [Title] The association of pulmonary lymphangioleiomyomatosis with renal and hepatic angiomyolipomas in a prepubertal girl: a previously unreported entity.
  • Pulmonary lymphangioleiomyomatosis (PLAM) is a rare, diffuse progressive interstitial lung disease that affects females of childbearing age and is characterized by diffuse proliferation of abnormal smooth muscle fibers predominantly developing in the lung and leading to cystic destruction.
  • A prepubertal 13-year-old girl with PLAM associated with renal and hepatic angiomyolipomas who was treated by nephroureterectomy and thoracoscopic pleurodesis is presented.
  • To the best of our knowledge, this is the first reported case of PLAM associated with renal and hepatic angiomyolipomas at the prepubertal age.
  • The most important clinical aid is to bear this rare entity in mind when a child presents with renal and/or hepatic angiomyolipomas.
  • [MeSH-major] Angiomyolipoma. Kidney Neoplasms. Liver Neoplasms. Lung Neoplasms. Lymphangioleiomyomatosis. Neoplasms, Multiple Primary

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  • [Copyright] (c) 2005 S. Karger AG, Basel.
  • (PMID = 15988170.001).
  • [ISSN] 0025-7931
  • [Journal-full-title] Respiration; international review of thoracic diseases
  • [ISO-abbreviation] Respiration
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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49. Lim SD, Stallcup W, Lefkove B, Govindarajan B, Au KS, Northrup H, Lang D, Fisher DE, Patel A, Amin MB, Arbiser JL: Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells? Mol Med; 2007 Mar-Apr;13(3-4):160-5
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  • [Title] Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells?
  • Angiomyolipomas are benign tumors of the kidney which express phenotypes of smooth muscle, fat, and melanocytes.
  • In order to determine whether angiomyolipomas, which exhibit smooth muscle and melanocytic phenotypes, express NG2 and L1, we performed immunocytochemistry on a cell line derived from a human angiomyolipoma, and found that these cells are uniformly positive.
  • Immunohistochemistry of human angiomyolipoma specimens revealed uniform staining of tumor cells, while renal cell carcinomas revealed positivity only of angiogenic vessels.
  • These results support a novel histogenesis of angiomyolipoma as a defect in differentiation of stem cell precursors.

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  • (PMID = 17592550.001).
  • [ISSN] 1076-1551
  • [Journal-full-title] Molecular medicine (Cambridge, Mass.)
  • [ISO-abbreviation] Mol. Med.
  • [Language] ENG
  • [Grant] United States / NIAMS NIH HHS / AR / P30 AR 42687; United States / NIAMS NIH HHS / AR / R01 AR050727; United States / NIAMS NIH HHS / AR / P30 AR042687; United States / NIAMS NIH HHS / AR / R01AR 47901; United States / NIAMS NIH HHS / AR / R01 AR 050727; United States / NIAMS NIH HHS / AR / R01 AR047901
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens; 0 / Biomarkers, Tumor; 0 / Leukocyte L1 Antigen Complex; 0 / Proteoglycans; 0 / chondroitin sulfate proteoglycan 4
  • [Other-IDs] NLM/ PMC1892760
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50. Nguyen KT, Chiu M: Segmental neurofibromatosis associated with renal angiomyolipomas. Cutis; 2008 Jul;82(1):65-8
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  • [Title] Segmental neurofibromatosis associated with renal angiomyolipomas.
  • Renal angiomyolipomas (AMLs) are rare benign neoplasms usually found in association with tuberous sclerosis (TS).
  • [MeSH-major] Angiomyolipoma / pathology. Facial Neoplasms / pathology. Kidney Neoplasms / pathology. Neurofibromatoses / pathology


51. Bishay VL, Crino PB, Wein AJ, Malkowicz SB, Trerotola SO, Soulen MC, Stavropoulos SW: Embolization of giant renal angiomyolipomas: technique and results. J Vasc Interv Radiol; 2010 Jan;21(1):67-72
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  • [Title] Embolization of giant renal angiomyolipomas: technique and results.
  • PURPOSE: To evaluate the efficacy and safety of prophylactic embolization of angiomyolipomas (AMLs) larger than 10 cm.
  • [MeSH-major] Angiomyolipoma / therapy. Antineoplastic Agents / therapeutic use. Ethanol / therapeutic use. Ethiodized Oil / therapeutic use. Kidney Neoplasms / therapy

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  • (PMID = 20123192.001).
  • [ISSN] 1535-7732
  • [Journal-full-title] Journal of vascular and interventional radiology : JVIR
  • [ISO-abbreviation] J Vasc Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Radiopharmaceuticals; 3K9958V90M / Ethanol; 8008-53-5 / Ethiodized Oil
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52. Israel GM, Hindman N, Hecht E, Krinsky G: The use of opposed-phase chemical shift MRI in the diagnosis of renal angiomyolipomas. AJR Am J Roentgenol; 2005 Jun;184(6):1868-72
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  • [Title] The use of opposed-phase chemical shift MRI in the diagnosis of renal angiomyolipomas.
  • OBJECTIVE: The objective of our study was to determine the reliability of the location of the india ink artifact and signal loss on opposed-phase chemical shift MRI to differentiate angiomyolipomas from solid renal masses and from hemorrhagic-proteinaceous renal cysts.
  • MATERIALS AND METHODS: Twenty-three angiomyolipomas, 24 hemorrhagic-proteinaceous cysts, and 23 solid renal masses (nonangiomyolipomas) were retrospectively evaluated at 1.5 T with chemical shift MRI using TEs of 2.1-2.7 msec (opposed phase) and 4.8-5.3 msec (in phase).
  • An angiomyolipoma was diagnosed if the india ink artifact was identified at the interface of the mass and the kidney or was present within the renal mass.
  • RESULTS: Twenty-three (100%) of the 23 angiomyolipomas showed india ink artifact within the mass or at its interface with the kidney, and 18 (78.3%) of the 23 angiomyolipomas showed signal loss on opposed-phase MR images.
  • CONCLUSION: The presence of india artifact at a renal mass-kidney interface or within a renal mass is indicative of angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 15908544.001).
  • [ISSN] 0361-803X
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / chinese ink; 7440-44-0 / Carbon
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53. Kang SG, Ko YH, Kang SH, Kim J, Kim CH, Park HS, Moon du G, Lee JG, Kim JJ, Cheon J: Two different renal cell carcinomas and multiple angiomyolipomas in a patient with tuberous sclerosis. Korean J Urol; 2010 Oct;51(10):729-32

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  • [Title] Two different renal cell carcinomas and multiple angiomyolipomas in a patient with tuberous sclerosis.
  • We report a case of tuberous sclerosis associated with two histologically different renal cell carcinomas (RCCs) and multiple angiomyolipomas (AMLs) in the same kidney.

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  • (PMID = 21031096.001).
  • [ISSN] 2005-6745
  • [Journal-full-title] Korean journal of urology
  • [ISO-abbreviation] Korean J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2963789
  • [Keywords] NOTNLM ; Angiomyolipoma / Clear cell renal carcinoma / Renal cell carcinoma / Tuberous sclerosis
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54. Chick CM, Tan BS, Cheng C, Taneja M, Lo R, Tan YH, Lin SE, Tay KH: Long-term follow-up of the treatment of renal angiomyolipomas after selective arterial embolization with alcohol. BJU Int; 2010 Feb;105(3):390-4
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  • [Title] Long-term follow-up of the treatment of renal angiomyolipomas after selective arterial embolization with alcohol.
  • OBJECTIVE: To present our institution's experience of selective embolization of renal angiomyolipomas with alcohol and the long-term follow up data.
  • CONCLUSION: Our study provides long-term evidence that selective arterial embolization with alcohol is a safe and effective method for improving clinical symptoms (85%) and preventing tumour progression (97%) in patients with renal angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / therapy. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Chemoembolization, Therapeutic / methods. Ethanol / administration & dosage. Iodized Oil / administration & dosage. Kidney Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Disease Progression. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / etiology. Radiography, Interventional. Retrospective Studies. Treatment Outcome. Young Adult

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  • [CommentIn] J Urol. 2011 Jan;185(1):99-100 [22082914.001]
  • (PMID = 19709070.001).
  • [ISSN] 1464-410X
  • [Journal-full-title] BJU international
  • [ISO-abbreviation] BJU Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 3K9958V90M / Ethanol; 8001-40-9 / Iodized Oil
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55. Patil AR, Chandra R, Gupta A, Thukral BB: Giant aneurysm formation in sporadic renal angiomyolipoma. J Radiol Case Rep; 2010;4(6):21-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant aneurysm formation in sporadic renal angiomyolipoma.
  • Angiomyolipomas are the most common mesenchymal renal neoplasms.
  • Two types have been described: (i) sporadic angiomyolipoma and (ii) angiomyolipoma associated with tuberous sclerosis.
  • Giant aneurysm formation is usually noted in angiomyolipomas associated with tuberous sclerosis and is rare in sporadic variety.
  • We report a rare case of aneurysm formation in a sporadic angiomyolipoma.

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  • (PMID = 22470737.001).
  • [ISSN] 1943-0922
  • [Journal-full-title] Journal of radiology case reports
  • [ISO-abbreviation] J Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3303414
  • [Keywords] NOTNLM ; Aneurysm / Angiomyolipoma / Computed Tomography / Tuberous Sclerosis complex
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56. Gould Rothberg BE, Grooms MC, Dharnidharka VR: Rapid growth of a kidney angiomyolipoma after initiation of oral contraceptive therapy. Obstet Gynecol; 2006 Sep;108(3 Pt 2):734-6
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  • [Title] Rapid growth of a kidney angiomyolipoma after initiation of oral contraceptive therapy.
  • BACKGROUND: Kidney angiomyolipomas are benign but progressive tumors consisting of smooth muscle, fat, and vascular elements, commonly associated with the tuberous sclerosis complex.
  • Angiomyolipomas express estrogen and progesterone receptors and have been reported to increase in size in pregnancy.
  • CASE: A 15-year-old girl with stable angiomyolipomas of tuberous sclerosis complex was treated for menorrhagia with estrogen/progestin oral contraceptive pills.
  • During the 12 months of contraceptive therapy, a new 4-cm exophytic angiomyolipoma developed that required selective arterial embolization to reduce its risk of spontaneous rupture.
  • CONCLUSION: Treating menorrhagia with exogenous hormonal therapy in women with tuberous sclerosis complex should be accompanied by regular renal imaging to reduce the risk of an unanticipated angiomyolipoma-related adverse event.
  • [MeSH-major] Angiomyolipoma / pathology. Contraceptives, Oral / adverse effects. Kidney Neoplasms / pathology. Menorrhagia / drug therapy

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  • (PMID = 17018483.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contraceptives, Oral
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57. Catalano OA, Samir AE, Sahani DV, Hahn PF: Pixel distribution analysis: can it be used to distinguish clear cell carcinomas from angiomyolipomas with minimal fat? Radiology; 2008 Jun;247(3):738-46
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  • [Title] Pixel distribution analysis: can it be used to distinguish clear cell carcinomas from angiomyolipomas with minimal fat?
  • PURPOSE: To retrospectively determine if pixel histogram analysis of unenhanced computed tomographic (CT) images can be used to distinguish angiomyolipomas (AMLs) with minimal fat from clear cell renal cell carcinomas (CCRCCs).
  • [MeSH-major] Adipose Tissue / radiography. Angiomyolipoma / radiography. Carcinoma, Renal Cell / radiography. Kidney Neoplasms / radiography. Radiographic Image Enhancement / methods. Radiographic Image Interpretation, Computer-Assisted / methods. Tomography, X-Ray Computed / methods

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  • [Copyright] (c) RSNA, 2008.
  • (PMID = 18413886.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Coumbaras M, Dahan H, Strauss C, Bouzar N, Lenoir S, Vallancien G, Palau R: [Renal angiomyolipoma complicated by extension to the renal vein and inferior vena cava]. J Radiol; 2006 May;87(5):572-4
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  • [Title] [Renal angiomyolipoma complicated by extension to the renal vein and inferior vena cava].
  • [Transliterated title] Angiomyolipome rénal compliqué d'une extension à la veine rénale et à la veine cave inférieure.
  • Renal angiomyolipomas are renal hamartomas.
  • We report a case of angiomyolipoma with sonographic and CT evidence of extension to the renal vein and inferior vena cava.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Renal Veins. Vascular Neoplasms / diagnosis. Vena Cava, Inferior

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  • (PMID = 16733416.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 12
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59. Martínez Barcina MJ, Quintian Schwieters C, Bonnin Sánchez D, Alberola Bou JM: [Intratumoral pseudoaneurysm: atypical radiologic manifestation of bleeding from an angiomyolipoma]. Radiologia; 2008 Jan-Feb;50(1):79-81
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  • [Title] [Intratumoral pseudoaneurysm: atypical radiologic manifestation of bleeding from an angiomyolipoma].
  • [Transliterated title] Pseudoaneurisma intratumoral: manifestación radiológica atípica del sangrado de un angiomiolipoma.
  • We present the case of a patient with tuberous sclerosis and multiple bilateral renal angiomyolipomas (AML) who developed an intralesional pseudoaneurysm in the context of bleeding from an AML.
  • [MeSH-major] Aneurysm, False / radiography. Angiomyolipoma / radiography. Hemorrhage / radiography. Kidney Neoplasms / radiography. Tuberous Sclerosis / complications

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  • (PMID = 18275794.001).
  • [ISSN] 0033-8338
  • [Journal-full-title] Radiología
  • [ISO-abbreviation] Radiologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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60. Abdulkader M, Abercrombie J, McCulloch TA, Kaye PV: Colonic angiomyolipoma with a monotypic expression and a predominant epithelioid component. J Clin Pathol; 2005 Oct;58(10):1107-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colonic angiomyolipoma with a monotypic expression and a predominant epithelioid component.
  • Angiomyolipomas are rare lesions, often arising in the kidney, and are part of a group of tumours with a diverse appearance and evidence of dual melanocytic and smooth muscle differentiation known as PEComas (tumours of perivascular epithelioid cell origin).
  • Unlike most of the previous colonic angiomyolipomas/PEComas reported in the literature, this case formed a large, mainly extrinsic mass and was monotypic, and composed entirely of the myomatous component with no adipose tissue or typical vasculature.
  • [MeSH-major] Angiomyolipoma / ultrastructure. Cecal Neoplasms / ultrastructure

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  • (PMID = 16189161.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1770749
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61. Vianna FG, Marchiori E, Zanetti G, Mano CM, Sarcinelli-Luz B, Carvalho JF, Assed C, Santos IG, Santos AA, Vianna AD: Tuberous sclerosis with pulmonary lymphangioleiomyomatosis and renal angiomyolipomas. Computed tomographic findings: a case report. Cases J; 2009;2:9238

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tuberous sclerosis with pulmonary lymphangioleiomyomatosis and renal angiomyolipomas. Computed tomographic findings: a case report.
  • The authors describe a case of a 31-year-old female with tuberous sclerosis, a genetic, rare, variably expressed disease.
  • Computed tomography scan of the abdomen revealed enlarged, heterogeneous kidneys, with low density tumors corresponding to angiomyolipomas.
  • Pulmonary lymphangioleiomyomatosis and bilateral renal angiomyolipomas are some presentations of tuberous sclerosis and the coexistence of both conditions may cause devastating morbidity and mortality.

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  • [Cites] N Engl J Med. 2006 Sep 28;355(13):1345-56 [17005952.001]
  • [Cites] Int Urol Nephrol. 2006;38(3-4):413-5 [17111084.001]
  • [Cites] AJR Am J Roentgenol. 2008 Jan;190(1):158-64 [18094306.001]
  • [Cites] N Engl J Med. 2008 Jan 10;358(2):140-51 [18184959.001]
  • [Cites] Chest. 2008 Feb;133(2):507-16 [18252917.001]
  • [Cites] Lancet. 2008 Aug 23;372(9639):657-68 [18722871.001]
  • [Cites] Radiology. 2003 Jan;226(1):33-46 [12511666.001]
  • [Cites] Mayo Clin Proc. 2000 Jun;75(6):591-4 [10852420.001]
  • [Cites] Thorax. 2000 Dec;55(12):1052-7 [11083892.001]
  • [Cites] Int Urol Nephrol. 2000;32(2):219-22 [11229634.001]
  • [Cites] Am J Respir Crit Care Med. 2001 Aug 15;164(4):669-71 [11520735.001]
  • [Cites] Respir Med. 2002 Jan;96(1):7-13 [11863212.001]
  • [Cites] Cases J. 2008;1(1):213 [18834543.001]
  • (PMID = 20184711.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2827144
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62. Hiromura T, Nishioka T, Tomita K: Spontaneous rupture of renal angiomyolipoma: value of multidetector CT angiography for interventional therapy. Emerg Radiol; 2005 Dec;12(1-2):53-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous rupture of renal angiomyolipoma: value of multidetector CT angiography for interventional therapy.
  • Renal angiomyolipomas have a high risk of rupture when they are large and associated with aneurysms.
  • When renal angiomyolipomas rupture, some patients go into shock.
  • [MeSH-major] Angiomyolipoma / diagnostic imaging. Kidney Neoplasms / diagnostic imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Acute Disease. Adult. Angiography. Back Pain / etiology. Contrast Media. Diagnosis, Differential. Embolization, Therapeutic. Female. Humans. Radiography, Interventional. Rupture, Spontaneous

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  • [Cites] Radiology. 2002 Oct;225(1):78-82 [12354988.001]
  • [Cites] AJR Am J Roentgenol. 2003 Jun;180(6):1633-8 [12760934.001]
  • [Cites] Semin Diagn Pathol. 1998 Feb;15(1):21-40 [9503504.001]
  • [Cites] Urology. 1985 May;25(5):461-7 [3887727.001]
  • [Cites] J Urol. 1993 Dec;150(6):1782-6 [8230504.001]
  • (PMID = 16317570.001).
  • [ISSN] 1070-3004
  • [Journal-full-title] Emergency radiology
  • [ISO-abbreviation] Emerg Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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63. Lane BR, Aydin H, Danforth TL, Zhou M, Remer EM, Novick AC, Campbell SC: Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid. J Urol; 2008 Sep;180(3):836-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid.
  • PURPOSE: Angiomyolipomas classically present radiographically as fat containing lesions but some fail to demonstrate fat content.
  • Histologically confirmed angiomyolipomas uniformly follow a benign course but rare epithelioid variants of angiomyolipoma can recur and metastasize.
  • We investigated the clinical, radiographic and histological characteristics of each angiomyolipoma subtype.
  • MATERIALS AND METHODS: Pertinent data were recorded for 209 patients surgically treated for angiomyolipoma in 219 kidneys from 1981 to 2007.
  • Classic and fat poor angiomyolipomas were classified radiographically based on the presence or absence of fat and classified histologically based on the presence of triphasic, monophasic or epithelioid histology.
  • RESULTS: Median radiographic size was 3.2, 4.9 and 10 cm in patients with a single angiomyolipoma (59% of patients), multiple angiomyolipomas and tuberous sclerosis (probable or definite), respectively.
  • In these 3 groups 65%, 47% and 33% of lesions were not suspected radiographically (fat poor angiomyolipoma).
  • Fat poor angiomyolipomas were more commonly single, smaller and in older patients.
  • Triphasic histology was evident in 76% of angiomyolipomas with 16% demonstrating a predominance of 1 component and 8% containing epithelioid features.
  • Despite potentially aggressive findings in 18% (eg presence within the perinephric fat, lymph node involvement) no angiomyolipoma recurred during a mean followup of 3.4 years (range 0 to 24).
  • A total of 28 (13%) patients with angiomyolipoma had concomitant renal cell carcinoma.
  • CONCLUSIONS: A surprisingly high number of resected angiomyolipomas was not suspected radiographically indicating the importance of precise radiographic characterization to minimize nephrectomy for fat poor angiomyolipoma, which should remain a research priority.
  • In this sizeable single institution series no triphasic, monophasic or epithelioid angiomyolipoma recurred despite potentially aggressive findings in a substantial proportion of cases.
  • [MeSH-major] Angiomyolipoma / classification. Kidney Neoplasms / classification

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  • (PMID = 18635231.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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64. Vianna FG, Marchiori E, Zanetti G, Mano CM, Sarcinelli-Luz B, Carvalho JF, Assed C, Santos IG, Santos AA, Vianna AD: Tuberous sclerosis with pulmonary lymphangioleiomyomatosis and renal angiomyolipomas. Computed tomographic findings: a case report. Cases J; 2009;2:9124

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tuberous sclerosis with pulmonary lymphangioleiomyomatosis and renal angiomyolipomas. Computed tomographic findings: a case report.
  • The authors describe a case of a 31-year-old female with tuberous sclerosis, a genetic, rare, variably expressed disease.
  • Computed tomography scan of the abdomen revealed enlarged, heterogeneous kidneys, with low density tumors corresponding to angiomyolipomas.
  • Pulmonary lymphangioleiomyomatosis and bilateral renal angiomyolipomas are some presentations of tuberous sclerosis and the coexistence of both conditions may cause devastating morbidity and mortality.

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  • [Cites] Mayo Clin Proc. 2000 Jun;75(6):591-4 [10852420.001]
  • [Cites] Respir Med. 2002 Jan;96(1):7-13 [11863212.001]
  • [Cites] Int Urol Nephrol. 2006;38(3-4):413-5 [17111084.001]
  • [Cites] N Engl J Med. 2008 Jan 10;358(2):140-51 [18184959.001]
  • [Cites] Lancet. 2008 Aug 23;372(9639):657-68 [18722871.001]
  • [Cites] Thorax. 2000 Dec;55(12):1052-7 [11083892.001]
  • [Cites] Cases J. 2008;1(1):213 [18834543.001]
  • [Cites] Am J Respir Crit Care Med. 2001 Aug 15;164(4):669-71 [11520735.001]
  • [Cites] Radiology. 2003 Jan;226(1):33-46 [12511666.001]
  • [Cites] N Engl J Med. 2006 Sep 28;355(13):1345-56 [17005952.001]
  • [Cites] AJR Am J Roentgenol. 2008 Jan;190(1):158-64 [18094306.001]
  • [Cites] Chest. 2008 Feb;133(2):507-16 [18252917.001]
  • [Cites] Int Urol Nephrol. 2000;32(2):219-22 [11229634.001]
  • (PMID = 20062701.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2803921
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65. Hayn MH, Cannon GM Jr, Bastacky S, Hrebinko RL: Renal cell carcinoma containing fat without associated calcifications: two case reports and review of literature. Urology; 2009 Feb;73(2):443.e5-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • With rare exceptions, angiomyolipomas can be distinguished from malignant renal masses by the presence of macroscopic fat within the mass.
  • We report 2 cases in which preoperative imaging with computed tomography was interpreted as diagnostic for angiomyolipoma, but the final pathologic analysis revealed clear cell renal cell carcinoma.

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  • (PMID = 18400269.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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66. Ellingson JJ, Coakley FV, Joe BN, Qayyum A, Westphalen AC, Yeh BM: Computed tomographic distinction of perirenal liposarcoma from exophytic angiomyolipoma: a feature analysis study. J Comput Assist Tomogr; 2008 Jul-Aug;32(4):548-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Computed tomographic distinction of perirenal liposarcoma from exophytic angiomyolipoma: a feature analysis study.
  • PURPOSE: To identify computed tomographic (CT) findings that distinguish perirenal liposarcomas from exophytic angiomyolipomas.
  • MATERIALS AND METHODS: We identified CT scans of 20 patients (13 women and 7 men; mean age, 63 years) with either perirenal liposarcoma (n = 11) proven at histopathology or large exophytic angiomyolipomas (n = 9) determined by 2-year stability (n = 6) or histopathology (n = 3).
  • RESULTS: A tumoral vessel extending into the renal cortex was seen only in angiomyolipomas (7 and 6 of 9 patients versus 0 and 0 of 11 liposarcomas for readers 1 and 2, respectively; P < 0.005 for both).
  • A parenchymal defect was more commonly seen in angiomyolipomas (7 and 6 of 9 angiomyolipomas versus 1 and 1 of 11 liposarcomas for readers 1 and 2, respectively; P < 0.05 for both).
  • Calcifications were seen by both readers in 6 of 11 liposarcomas but not in any angiomyolipomas (P < 0.05).
  • CONCLUSIONS: In the evaluation of a fatty perinephric mass at CT, the presence of a tumoral vessel extending into the renal cortex or a renal parenchymal defect at the site of tumor contact strongly favors the diagnosis of exophytic angiomyolipoma, whereas calcifications suggest liposarcoma.

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  • [Cites] J Urol. 2002 Feb;167(2 Pt 1):490-3 [11792904.001]
  • [Cites] AJR Am J Roentgenol. 2002 Sep;179(3):769-73 [12185060.001]
  • [Cites] J Comput Assist Tomogr. 2003 Sep-Oct;27(5):799-804 [14501373.001]
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  • (PMID = 18664840.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] ENG
  • [Grant] United States / NIBIB NIH HHS / EB / EB001631-01A1; United States / NIBIB NIH HHS / EB / T32 EB001631; United States / NIBIB NIH HHS / EB / T32 EB001631-01A1
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 117-96-4 / Diatrizoate; 4419T9MX03 / Iohexol
  • [Other-IDs] NLM/ NIHMS125523; NLM/ PMC2748260
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67. Zhang X, Yan SX, Xiao WB, Pan Y, Xu SL: [Correlation between pathology and imaging characteristics of hepatic agiomyolipoma]. Zhejiang Da Xue Xue Bao Yi Xue Ban; 2007 Jan;36(1):88-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To discuss CT and MRI characteristics of hepatic angiomyolipoma based on pathological findings.
  • METHODS: The CT and MRI appearances with related pathohistological subtypes of 11 hepatic angiomyolipomas from 10 patients were retrospectively analyzed.
  • RESULT: Ten patients with hepatic angiomyolipomas were subcategorized into lipomatous (3 cases), angiomatous (1 case), myomatous (1 case) and mixed (5 cases) subtypes.
  • CONCLUSION: The discrete CT and MRI appearances of hepatic angiomyolipomas with different pathological subtypes depend on the components of the tumor.
  • [MeSH-major] Angiomyolipoma / pathology. Liver Neoplasms / pathology. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 17290498.001).
  • [ISSN] 1008-9292
  • [Journal-full-title] Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
  • [ISO-abbreviation] Zhejiang Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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68. Ginat DT, Saad WE, Turba UC: Transcatheter renal artery embolization for management of renal and adrenal tumors. Tech Vasc Interv Radiol; 2010 Jun;13(2):75-88
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Transcatheter arterial embolization is a minimally invasive procedure that is increasingly used for the management of angiomyolipomas and to augment and/or palliate the management of malignant renal and adrenal neoplasms.
  • The most common indications for renal artery embolization include (1) prenephrectomy and preradiofrequency ablation infarction of renal tumors, (2) management of renal angiomyolipomas, (3) palliations of unresectable renal malignancy, and (4) malignant renal hemorrhage (life-threatening or chronic debilitating hematuria).
  • Although there is less extensive literature available regarding the use of transcatheter embolization of adrenal tumors, this technique appears to be effective and safe for palliation and preadrenalectomy of adrenal metastatic disease, adrenocortical carcinomas, as well as treatment of symptomatic aldosteronomas.

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20540917.001).
  • [ISSN] 1557-9808
  • [Journal-full-title] Techniques in vascular and interventional radiology
  • [ISO-abbreviation] Tech Vasc Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 31
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69. Mantas D, Papachristodoulou A: Bilateral renal angiomyolipoma. Acta Chir Belg; 2006 Nov-Dec;106(6):707-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral renal angiomyolipoma.
  • Angiomyolipomas are frequent tumours of the kidneys.
  • In this case report, we present an acute surgical condition due to rupture and haemorrhage of a giant angiomyolipoma.
  • In addition, we review the literature on angiomyolipomas and their severe complications in order to help young surgeons who may be involved in such difficult and life-threatening cases as ours.
  • [MeSH-major] Angiomyolipoma / surgery. Kidney Neoplasms / surgery

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  • (PMID = 17290701.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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70. Cantwell CP, Taubman KE, Scorza LB: Absolute alcohol embolization of sporadic angiomyolipoma. Semin Intervent Radiol; 2008 Sep;25(3):319-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Absolute alcohol embolization of sporadic angiomyolipoma.
  • Angiomyolipoma is a benign hamartoma.
  • Seventy percent of angiomyolipomas occur sporadically in the general population and the remainder are associated with a syndrome.
  • Of patients with tuberous sclerosis, 60 to 80% have an angiomyolipoma.
  • Sporadic angiomyolipomas tend to be single and occur in an older age group.
  • We describe a case of a sporadic asymptomatic angiomyolipoma treated with absolute alcohol embolization.

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  • [Cites] Invest Radiol. 2002 Sep;37(9):512-20 [12218447.001]
  • [Cites] Radiology. 2004 Jul;232(1):147-53 [15220499.001]
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  • (PMID = 21326521.001).
  • [ISSN] 0739-9529
  • [Journal-full-title] Seminars in interventional radiology
  • [ISO-abbreviation] Semin Intervent Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3036442
  • [Keywords] NOTNLM ; Angiomyolipoma / ablation / alcohol / embolization / fibromuscular dysplasia / renal disorders
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71. Wahab S, Ahmad Khan R, Thapa M, Wahab A, Ahmad I: Giant angiomyolipoma associated with a dilated vessel prone to hemorrhage. Iran J Kidney Dis; 2009 Jul;3(3):168-71
MedlinePlus Health Information. consumer health - Kidney Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant angiomyolipoma associated with a dilated vessel prone to hemorrhage.
  • Angiomyolipomas are benign neoplasms of the kidney which can clinically mimic renal malignancy.
  • We report a case of giant angiomyolipoma with a dilated vessel susceptible to hemorrhage.
  • [MeSH-major] Angiomyolipoma / complications. Hemorrhage / etiology. Kidney Neoplasms / complications. Severity of Illness Index

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  • (PMID = 19617667.001).
  • [ISSN] 1735-8582
  • [Journal-full-title] Iranian journal of kidney diseases
  • [ISO-abbreviation] Iran J Kidney Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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72. Garcia-Covarrubias L, McGee J, Landes J, Florman SS, Slakey DP: Cadaveric kidney transplant complicated by rupture of native kidney angiomyolipoma: a case report and review of the literature. Am Surg; 2005 Apr;71(4):286-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cadaveric kidney transplant complicated by rupture of native kidney angiomyolipoma: a case report and review of the literature.
  • Kidneys with angiomyolipomas have been used for transplantation, but we are unaware of postoperative hemorrhage from a native kidney angiomyolipoma.
  • A 49-year-old male who underwent a cadaveric renal transplant complicated by postoperative hemorrhage from a native kidney angiomyolipoma is presented.
  • [MeSH-major] Angiomyolipoma / etiology. Kidney Neoplasms / etiology. Kidney Transplantation / adverse effects. Postoperative Hemorrhage / etiology

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  • (PMID = 15943399.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
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73. Silverman SG, Mortele KJ, Tuncali K, Jinzaki M, Cibas ES: Hyperattenuating renal masses: etiologies, pathogenesis, and imaging evaluation. Radiographics; 2007 Jul-Aug;27(4):1131-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Possible malignant causes include renal cell carcinoma and lymphoma; benign causes include angiomyolipoma with minimal fat.
  • However, some solid, enhancing, hyperattenuating masses cannot be diagnosed confidently with CT alone: Small (< or = 3-cm-diameter), homogeneously enhancing, hyperattenuating renal masses depicted on CT images may be either benign angiomyolipomas with minimal fat or renal cell carcinomas.
  • Magnetic resonance (MR) imaging may be helpful for differentiating between angiomyolipomas with minimal fat and clear cell renal cell carcinomas; however, differentiation between angiomyolipomas with minimal fat and papillary renal cell carcinomas often is not possible on the basis of MR imaging.

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  • [Copyright] RSNA, 2007
  • (PMID = 17620471.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 52
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74. Storm DW, Mowad JJ: Conservative management of a bleeding renal angiomyolipoma in pregnancy. Obstet Gynecol; 2006 Feb;107(2 Pt 2):490-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conservative management of a bleeding renal angiomyolipoma in pregnancy.
  • BACKGROUND: Bleeding angiomyolipomas in pregnancy are rare but may be devastating and potentially fatal.
  • CASE: A 32-year-old woman with known bilateral angiomyolipomas presented at 39 weeks of gestation with acute onset left flank pain.
  • The ultrasound result was consistent with a bleeding angiomyolipoma.
  • CONCLUSION: Bleeding angiomyolipomas in pregnancy were managed successfully through conservative management and vaginal delivery.
  • [MeSH-major] Angiomyolipoma / therapy. Kidney Neoplasms / therapy. Pregnancy Complications, Neoplastic / therapy

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  • (PMID = 16449160.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Nabi N, Shaikh AH, Khalid SE: Tuberous sclerosis with bilateral renal angiomyolipoma and wunderlich's syndrome. J Coll Physicians Surg Pak; 2007 Nov;17(11):706-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tuberous sclerosis with bilateral renal angiomyolipoma and wunderlich's syndrome.
  • This case describes a 47-year-old female with tuberous sclerosis associated with bilateral giant renal angiomyolipomas.
  • After four months, she required emergency nephrectomy due to spontaneous hemorrhage from the angiomyolipoma (Wunderlich's syndrome).

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  • (PMID = 18070586.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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76. Paradis V: Benign liver tumors: an update. Clin Liver Dis; 2010 Nov;14(4):719-29
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  • In the absence of underlying chronic liver disease, the vast majority of these lesions correspond to benign liver tumors including solid and cystic lesions.
  • This article is dedicated to hepatocellular tumors and also addresses hemangiomas as the most common benign liver tumors, and angiomyolipomas as a rare tumor often misdiagnosed.
  • [MeSH-major] Adenoma, Liver Cell / pathology. Angiomyolipoma / pathology. Carcinoma, Hepatocellular / pathology. Hemangioma / pathology. Liver Neoplasms / pathology

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21055692.001).
  • [ISSN] 1557-8224
  • [Journal-full-title] Clinics in liver disease
  • [ISO-abbreviation] Clin Liver Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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77. Culty T, Molinie V, Lebret T, Savareux L, Souid M, Delahousse M, Botto H: TSC2/PKD1 contiguous gene syndrome in an adult. Minerva Urol Nefrol; 2006 Dec;58(4):351-4
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  • A 48-year-old woman with a history of autosomal-dominant polycystic kidney disease (ADPKD), was found to have multiple renal angiomyolipomas on a pathological examination after nephrectomy.
  • [MeSH-major] Angiomyolipoma / genetics. Polycystic Kidney, Autosomal Dominant / genetics. TRPP Cation Channels. Tuberous Sclerosis / genetics. Tumor Suppressor Proteins / genetics

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  • (PMID = 17268401.001).
  • [ISSN] 0393-2249
  • [Journal-full-title] Minerva urologica e nefrologica = The Italian journal of urology and nephrology
  • [ISO-abbreviation] Minerva Urol Nefrol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / TRPP Cation Channels; 0 / Tumor Suppressor Proteins; 0 / polycystic kidney disease 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein
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78. Singh D, Kashyap S, Kaur S: Renal angiomyolipoma, a diagnostic dilemma: a case report. Indian J Pathol Microbiol; 2007 Jul;50(3):622-3
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  • [Title] Renal angiomyolipoma, a diagnostic dilemma: a case report.
  • Angiomyolipomas are the most common benign mesenchymal tumours of the kidney.
  • Most of the angiomyolipomas in adults are asymptomatic and discovered incidentally.
  • Radiological and fine needle aspiration cytology (FNAC) report of a malignant retroperitoneal tumour was given, but histological examination of the respective tumorous mass showed a benign renal tumour - angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Retroperitoneal Neoplasms / diagnosis

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  • (PMID = 17883164.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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79. Rau KC, Awad ZT, Aucar JA: Laparoscopic cholecystectomy in the presence of lymphangiomyomatosis. Surg Laparosc Endosc Percutan Tech; 2005 Apr;15(2):104-5
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  • A 49-year-old woman with a history of generalized lymphangiomyomatosis or lymphangioleiomyomatosis (LAM), including angiomyolipomas of the liver and kidney and known LAM of the lung, presented with symptomatic cholelithiasis.
  • A CT scan of the abdomen is of value to delineate the anatomy of the angiomyolipomas and their proximity to the operative site.

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  • (PMID = 15821625.001).
  • [ISSN] 1530-4515
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Henske EP: Tuberous sclerosis and the kidney: from mesenchyme to epithelium, and beyond. Pediatr Nephrol; 2005 Jul;20(7):854-7
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  • The renal manifestations of tuberous sclerosis complex (TSC) are remarkably diverse, including polycystic kidney disease, oncocytomas, renal cell carcinomas, and both benign and malignant angiomyolipomas.
  • Benign angiomyolipomas, which can cause spontaneous life-threatening hemorrhage, are by far the most prevalent and the greatest source of morbidity.
  • What is particularly unusual about TSC, setting it apart from virtually all other inherited forms of renal disease, is the abnormalities of both mesenchymal cells (angiomyolipomas) and epithelial cells (cysts, oncocytomas, and carcinomas).
  • Here, we will address the genetic, cellular and biochemical mechanisms that may contribute to the unusually broad spectrum of renal disease in cells with TSC1 or TSC2 mutations, and consider how the TSC signaling pathways may be linked to other renal diseases such as polycystic kidney disease and renal cell carcinoma.
  • [MeSH-major] Angiomyolipoma / etiology. Carcinoma / etiology. Kidney Neoplasms / etiology. Tuberous Sclerosis / complications

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  • (PMID = 15856327.001).
  • [ISSN] 0931-041X
  • [Journal-full-title] Pediatric nephrology (Berlin, Germany)
  • [ISO-abbreviation] Pediatr. Nephrol.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / DK 51052
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Repressor Proteins; 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein
  • [Number-of-references] 43
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81. Karbowniczek M, Henske EP: The role of tuberin in cellular differentiation: are B-Raf and MAPK involved? Ann N Y Acad Sci; 2005 Nov;1059:168-73
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  • This review focuses on the genetic and biochemical basis of the renal and pulmonary manifestations of TSC, angiomyolipomas, and lymphangiomyomatosis, respectively.
  • Genetic analyses of sporadic angiomyolipomas revealed that all three components (smooth muscle, vessels, and fat) derive from a common progenitor cell, indicating the ability of cells lacking tuberin to differentiate into multiple lineages.
  • We hypothesize that aberrant B-Raf activity in angiomyolipomas leads to abnormal cellular differentiation and migration.
  • [MeSH-minor] Angiomyolipoma / metabolism. Animals. Cell Differentiation. Cell Movement. Humans. Models, Biological. Neoplasm Metastasis. Signal Transduction

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  • (PMID = 16382052.001).
  • [ISSN] 0077-8923
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; 4JG2LF96VF / tuberous sclerosis complex 2 protein; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
  • [Number-of-references] 50
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82. Schreiner A, Daneshmand S, Bayne A, Countryman G, Corless CL, Troxell ML: Distinctive morphology of renal cell carcinomas in tuberous sclerosis. Int J Surg Pathol; 2010 Oct;18(5):409-18
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  • The syndrome is characterized by hamartomas and neoplastic lesions, including angiomyolipomas of the kidney and other organs.
  • Renal cell carcinoma (RCC) in tuberous sclerosis remains relatively poorly characterized because historical studies were confounded by the inclusion of epithelioid angiomyolipomas.
  • The authors present a patient with tuberous sclerosis and bilateral renal lesions, including multiple minute angiomyolipomas, cortical cysts, and 4 separate RCCs of unclassified type.

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  • (PMID = 19403547.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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83. Singh K, Pai RR, Kini H, Kini UA: Cutaneous angiomyolipoma. Indian J Pathol Microbiol; 2009 Apr-Jun;52(2):242-3
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  • [Title] Cutaneous angiomyolipoma.
  • Cutaneous angiomyolipomas are rare.
  • This lesion, probably hamartomatous in nature, differs from renal angiomyolipoma in terms of nonassociation with tuberous sclerosis, circumscription, and male predominance.
  • [MeSH-major] Angiomyolipoma / diagnosis. Chin / pathology. Skin Neoplasms / pathology

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  • (PMID = 19332927.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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84. Wang Z, Xu HX, Xie XY, Xie XH, Kuang M, Xu ZF, Liu GJ, Chen LD, Lin MX, Lu MD: Imaging features of hepatic angiomyolipomas on real-time contrast-enhanced ultrasound. Br J Radiol; 2010 May;83(989):411-8
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  • [Title] Imaging features of hepatic angiomyolipomas on real-time contrast-enhanced ultrasound.
  • The aim of this study was to evaluate the imaging features of hepatic angiomyolipoma (AML) on contrast-enhanced ultrasound (CEUS).
  • [MeSH-major] Angiomyolipoma / ultrasonography. Liver Neoplasms / ultrasonography

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  • (PMID = 19723766.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media
  • [Other-IDs] NLM/ PMC3473573
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85. Sokolova IN, Savelov NA, Chistiakova OV, Sorokin KV, Gurariĭ LL, Shatinina NN: [Angiomyolipoma of the kidneys]. Arkh Patol; 2005 Nov-Dec;67(6):38-43
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  • [Title] [Angiomyolipoma of the kidneys].
  • 59 angiomyolipomas were studied: immunohistochemistry (IHC) was used in 24 cases, electron microscopy (EM) in 6 cases.
  • [MeSH-major] Angiomyolipoma / ultrastructure. Kidney / ultrastructure. Kidney Neoplasms / ultrastructure. Melanosomes / ultrastructure

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  • (PMID = 16405021.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Actins
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86. Haritharan T, Sritharan S, Bhimji S: Renal angiomyolipoma with inferior vena caval involvement. Med J Malaysia; 2006 Oct;61(4):493-5
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  • [Title] Renal angiomyolipoma with inferior vena caval involvement.
  • Renal angiomyolipomas are innocuous benign tumours which rarely behave aggressively.
  • She was diagnosed with renal angiomyolipoma of the right kidney complicated by inferior vena caval tumour thrombosis.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology. Vascular Neoplasms / secondary. Vena Cava, Inferior / pathology

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  • (PMID = 17243531.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
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87. Soler-Ferrer C, Gómez-Lozano A, Clemente-Andrés C, De Cendra-Morera E, Custal-Teixidor M, Colomer-Pairés J: [Lymphangioleiomyomatosis in a post-menopausal women]. Arch Bronconeumol; 2010 Mar;46(3):148-50
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  • Lymphangioleiomyomatosis is a rare disease characterised by pulmonary cysts with abnormal proliferation in the lymphatic system.
  • It is known that this diseases is strongly associated with other conditions, such as tuberous sclerosis and renal angiomyolipomas.
  • We present a case of a post-menopausal patient suffering from lymphangioleiomyomatosis, with no history of hormone therapy, in whom were also detected renal angiomyolipomas and clinical signs indicative of a probable tuberous sclerosis.

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  • [Copyright] Copyright 2009 SEPAR. Published by Elsevier Espana. All rights reserved.
  • (PMID = 19783087.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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88. Simpfendorfer C, Herts BR, Motta-Ramirez GA, Lockwood DS, Zhou M, Leiber M, Remer EM: Angiomyolipoma with minimal fat on MDCT: can counts of negative-attenuation pixels aid diagnosis? AJR Am J Roentgenol; 2009 Feb;192(2):438-43
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  • [Title] Angiomyolipoma with minimal fat on MDCT: can counts of negative-attenuation pixels aid diagnosis?
  • OBJECTIVE: The purpose of this study was to determine whether counts of pixels with subzero attenuation on CT scans can aid in the diagnosis of renal angiomyolipoma with minimal fat.
  • MATERIALS AND METHODS: Of 33 angiomyolipomas identified among 719 renal masses resected from 702 patients over 4 years, 15 masses in 15 patients were prospectively diagnosed on the basis of the presence of fat at MDCT.
  • The 18 patients with minimal-fat angiomyolipoma and a matched (age, sex, tumor size) cohort of patients with renal cell carcinoma were included in this study.
  • RESULTS: Using criterion 1, reader A identified six angiomyolipomas; reader B, five; and reader C, two.
  • Using criterion 2, reader A identified three angiomyolipomas; reader B, four; and reader C, two.
  • Using criterion 3, reader A identified four angiomyolipomas; reader B, four; and reader C, two.
  • CONCLUSION: CT findings of more than 20 pixels with attenuation less than -20 HU and more than 5 pixels with attenuation less than -30 HU have a positive predictive value of 100% in detection of angiomyolipoma, but most angiomyolipomas with minimal fat cannot be reliably identified on the basis of an absolute pixel count.
  • [MeSH-major] Angiomyolipoma / radiography. Kidney Neoplasms / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 19155407.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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89. Boorjian SA, Frank I, Inman B, Lohse CM, Cheville JC, Leibovich BC, Blute ML: The role of partial nephrectomy for the management of sporadic renal angiomyolipoma. Urology; 2007 Dec;70(6):1064-8
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  • [Title] The role of partial nephrectomy for the management of sporadic renal angiomyolipoma.
  • OBJECTIVES: Angiomyolipoma is a benign renal tumor that has a propensity to grow over time and may cause local complications.
  • We evaluated our experience with nephron-sparing surgery for renal angiomyolipoma.
  • METHODS: We reviewed our institutional nephrectomy registry to identify patients treated with nephron-sparing surgery for renal angiomyolipoma between 1970 and 2004.
  • RESULTS: We identified 58 patients treated with nephron-sparing surgery for sporadic renal angiomyolipoma, including 44 women and 14 men.
  • In 7 patients (12%), several ipsilateral angiomyolipomas were resected, whereas 2 patients were treated with nephron-sparing surgery for bilateral angiomyolipomas.
  • No patient developed de novo chronic renal insufficiency after nephron-sparing surgery, including 4 patients treated for angiomyolipomas in a solitary kidney.
  • CONCLUSIONS: Nephron-sparing surgery for sporadic renal angiomyolipomas offers preservation of renal function and is associated with acceptable complication and low local recurrence rates.
  • [MeSH-major] Angiomyolipoma / surgery. Kidney Neoplasms / surgery. Nephrectomy

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  • (PMID = 18158015.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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90. Obara W, Sato K, Owari Y, Nozawa T, Isurugi K, Ohmori S, Matsushita Y, Tanji S, Konda R, Fujioka T: Perinephric angiomyolipoma: a unique development pattern surrounding the kidney. Int J Urol; 2005 Mar;12(3):305-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Perinephric angiomyolipoma: a unique development pattern surrounding the kidney.
  • We report a case of a 31-year-old man with extrarenal angiomyolipoma of the perinephric space.
  • Extrarenal angiomyolipomas of the perinephric fat are rare and they should be considered in the differential diagnosis of a retroperitoneal mass where asymptomatic macrohematuria was presented at the onset.
  • [MeSH-major] Angiomyolipoma / radiography. Kidney Neoplasms / radiography. Retroperitoneal Neoplasms / radiography

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  • (PMID = 15828960.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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91. Colović R, Colović N, Grubor N, Radak V, Micev M, Stojković M: [Bilateral angiomyolipoma of the kidney in patient with tuberous sclerosis]. Srp Arh Celok Lek; 2005 Sep-Oct;133(9-10):433-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Bilateral angiomyolipoma of the kidney in patient with tuberous sclerosis].
  • Angiomyolipomas are relatively frequent tumours of the kidney.
  • Due to the benign nature of angiomyolipomas, surgical treatment and embolisation of the tumours are generally not recommended, unless renal function is endangered, the symptoms are severe, or the kidney in question becomes completely dysfunctional.
  • We present a 24-year-old woman with tuberous sclerosis in whom bilateral kidney tumours were diagnosed 7 years earlier and in whom we carried out a left nephrectomy of a 5300 gram angiomyolipoma, which caused pain and complete loss of function.
  • [MeSH-major] Angiomyolipoma / complications. Kidney Neoplasms / complications. Tuberous Sclerosis / complications

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  • (PMID = 16640189.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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92. Kato N, Honma K, Hojo H, Sasou S, Matsuzaki O, Motoyama T: KIT expression in normal and neoplastic renal tissues: immunohistochemical and molecular genetic analysis. Pathol Int; 2005 Aug;55(8):479-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • KIT expression in angiomyolipoma and congenital mesoblastic nephroma (CMN), is still controversial. c-kit mutations are reportedly rare in ChCC, but there is little information in other renal neoplasms, and no reported data on mutations of platelet-derived growth factor receptor (PDGFR).
  • In order to address these issues the authors examined five ChCC, five oncocytomas, seven papillary cell carcinomas, two collecting duct carcinomas, 12 angiomyolipomas, and three CMN, as well as 10 normal renal tissues.
  • Nine of 12 (75%) angiomyolipomas contained scattered KIT-positive cells, whereas all three CMN were completely negative for KIT.
  • The presence of KIT-positive cells in angiomyolipomas was likely to correspond to that of melanocytic marker-positive cells, which mainly showed epithelioid morphology.
  • [MeSH-minor] Adenoma, Oxyphilic / genetics. Adenoma, Oxyphilic / metabolism. Adenoma, Oxyphilic / pathology. Angiomyolipoma / genetics. Angiomyolipoma / metabolism. Angiomyolipoma / pathology. Carcinoma, Papillary / genetics. Carcinoma, Papillary / metabolism. Carcinoma, Papillary / pathology. DNA Mutational Analysis. Gene Expression. Humans. Immunohistochemistry. Kidney Tubules, Collecting / chemistry. Kidney Tubules, Collecting / metabolism. Kidney Tubules, Collecting / pathology. Nephroma, Mesoblastic / genetics. Nephroma, Mesoblastic / metabolism. Nephroma, Mesoblastic / pathology. Polymerase Chain Reaction. Polymorphism, Single-Stranded Conformational. Receptor, Platelet-Derived Growth Factor alpha / biosynthesis. Receptor, Platelet-Derived Growth Factor alpha / genetics

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  • (PMID = 15998375.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha
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93. Nepple KG, Bockholt NA, Dahmoush L, Williams RD: Giant renal angiomyolipoma without fat density on CT scan: case report and review of the literature. ScientificWorldJournal; 2010;10:1334-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant renal angiomyolipoma without fat density on CT scan: case report and review of the literature.
  • Giant renal angiomyolipomas have been reported, but typically have the pathognomonic finding of fat density on CT scan.
  • We present the case of a 53-year-old male with a symptomatic, 35-cm, predominantly cystic renal mass without fat density on CT that on nephrectomy was found to be a fat-poor angiomyolipoma with predominantly epithelioid morphology weighing 17.9 kg.
  • Giant renal angiomyolipoma without macroscopic fat density on CT scan is an exceedingly rare occurrence.
  • [MeSH-major] Angiomyolipoma / radiography. Kidney Neoplasms / radiography

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  • (PMID = 20623093.001).
  • [ISSN] 1537-744X
  • [Journal-full-title] TheScientificWorldJournal
  • [ISO-abbreviation] ScientificWorldJournal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 24
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94. Lin CY, Chen HY, Jwo SC, Chan SC: Ileal angiomyolipoma as an unusual cause of small-intestinal intussusception. J Gastroenterol; 2005 Feb;40(2):200-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ileal angiomyolipoma as an unusual cause of small-intestinal intussusception.
  • Angiomyolipomas are benign mesenchymal tumors, but those that arise from the small intestine are exceedingly rare.
  • We report on a 48-year-old woman who had an ileal angiomyolipoma, who presented clinically with vague abdominal pain and bloody stool.
  • [MeSH-major] Angiomyolipoma / complications. Ileal Neoplasms / complications. Intussusception / etiology

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  • (PMID = 15770405.001).
  • [ISSN] 0944-1174
  • [Journal-full-title] Journal of gastroenterology
  • [ISO-abbreviation] J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Desmin
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95. Mongha R, Bansal P, Dutta A, Das RK, Kundu AK: Wunderlich's syndrome with hepatic angiomyolipoma in tuberous sclerosis. Indian J Cancer; 2008 Apr-Jun;45(2):64-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Wunderlich's syndrome with hepatic angiomyolipoma in tuberous sclerosis.
  • We present a patient of tuberous sclerosis complex with bilateral renal angiomyolipoma and hepatic angiomyolipoma with spontaneous retroperitoneal hemorrhage from right angiomyolipoma (Wunderlich's syndrome).
  • Hepatic angiomyolipoma was managed conservatively.
  • Wunderlich's syndrome has been found in around 10% of cases of renal angiomyolipomas.
  • Hepatic Angiomyolipoma is a benign mesenchymal neoplasm of the liver which is rarely reported in literature.
  • [MeSH-major] Angiomyolipoma / complications. Hemorrhage / etiology. Kidney Diseases / etiology. Kidney Neoplasms / complications. Liver Neoplasms / complications. Tuberous Sclerosis / complications


96. Jeon TY, Kim SH, Lim HK, Lee WJ: Assessment of triple-phase CT findings for the differentiation of fat-deficient hepatic angiomyolipoma from hepatocellular carcinoma in non-cirrhotic liver. Eur J Radiol; 2010 Mar;73(3):601-6
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  • [Title] Assessment of triple-phase CT findings for the differentiation of fat-deficient hepatic angiomyolipoma from hepatocellular carcinoma in non-cirrhotic liver.
  • BACKGROUND: To evaluate the triple-phase CT findings for the differentiation of fat-deficient angiomyolipoma from hepatocellular carcinoma in non-cirrhotic liver.
  • METHODS: We retrospectively reviewed contrast-enhanced triple-phase CT images of 10 patients with fat-deficient hepatic angiomyolipoma and 28 patients with 29 hepatocellular carcinomas in non-cirrhotic liver proved on histologic examination.
  • RESULTS: Early draining vein depicted on arterial or portal phases was seen in eight (80%) angiomyolipomas and two hepatocellular carcinomas (7%) (p<0.001), in which the early draining vein was connected with tumoral vessels.
  • The tumoral vessels in the angiomyolipoma were more prominent and ectatic, were distributed both centrally and peripherally, and were seen in smaller tumors than in the hepatocellular carcinoma.
  • Tumor capsule enhancement was absent in all angiomyolipomas as compared with two (7%) hepatocellular carcinomas with no tumor capsule (p<0.001).
  • CONCLUSIONS: The presence of early draining vein connecting with prominent tumoral vessels and absent tumor capsule were useful CT findings for the differentiation of fat-deficient angiomyolipoma from hepatocellular carcinoma in non-cirrhotic liver.
  • [MeSH-major] Angiomyolipoma / radiography. Carcinoma, Hepatocellular / radiography. Liver Neoplasms / radiography. Tomography, X-Ray Computed / methods

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  • [Copyright] Copyright 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19200676.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media; JR13W81H44 / Iopamidol
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97. Tan YS, Yip KH, Tan PH, Cheng WS: A right renal angiomyolipoma with IVC thrombus and pulmonary embolism. Int Urol Nephrol; 2010 Jun;42(2):305-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A right renal angiomyolipoma with IVC thrombus and pulmonary embolism.
  • Angiomyolipomas (AML) are benign lesions, commonly found in the kidney, where they may be single or multiple.
  • [MeSH-major] Angiomyolipoma / complications. Angiomyolipoma / pathology. Kidney Neoplasms / complications. Kidney Neoplasms / pathology. Neoplastic Cells, Circulating. Pulmonary Embolism / etiology. Vena Cava, Inferior

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  • (PMID = 19609707.001).
  • [ISSN] 1573-2584
  • [Journal-full-title] International urology and nephrology
  • [ISO-abbreviation] Int Urol Nephrol
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98. Lee CH, Kim JH, Yang DH, Hwang Y, Kang MJ, Kim YK, Lee MR: Ileal angiomyolipoma manifested by small intestinal intussusception. World J Gastroenterol; 2009 Mar 21;15(11):1398-400
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ileal angiomyolipoma manifested by small intestinal intussusception.
  • Angiomyolipomas (AMLs), a form of benign mesenchymal hamartoma, arise primarily in the kidneys of patients with or without tuberous sclerosis.
  • [MeSH-major] Angiomyolipoma / diagnosis. Ileal Neoplasms / diagnosis

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  • (PMID = 19294773.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2658844
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99. Dvorakovskaia IV, Baranova OP: [Pulmonary lymphangioleiomyomatosis]. Arkh Patol; 2005 Sep-Oct;67(5):29-32
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  • Expression of NMB-45, desmin, actin, vimentin prove myogenic nature of the disease and confirm combination of two morphogenesis directions - proliferation of smooth muscle cells at the active phase of the growth and fibrosis at late stages.
  • Thus, LAM is multisystem disease linked with abdominal tumors (angiomyolipomas, angioleiomyomas).

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  • (PMID = 16323477.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Cytoskeletal Proteins; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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100. Pan CC, Chung MY, Ng KF, Liu CY, Wang JS, Chai CY, Huang SH, Chen PC, Ho DM: Constant allelic alteration on chromosome 16p (TSC2 gene) in perivascular epithelioid cell tumour (PEComa): genetic evidence for the relationship of PEComa with angiomyolipoma. J Pathol; 2008 Feb;214(3):387-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Constant allelic alteration on chromosome 16p (TSC2 gene) in perivascular epithelioid cell tumour (PEComa): genetic evidence for the relationship of PEComa with angiomyolipoma.
  • Perivascular epithelioid cell tumours (PEComas) are a family of tumours including classic angiomyolipoma, lymphangioleiomyomatosis, and clear epithelioid cell tumours reported under a variety of names such as epithelioid angiomyolipoma, pulmonary and extrapulmonary clear cell sugar tumour, and PEComa.
  • We collected ten sporadic and two tuberous sclerosis complex-associated PEComas, as well as 14 sporadic classic hepatic and renal angiomyolipomas (AMLs) as controls.
  • Six classic angiomyolipomas had allelic changes at chromosome 16p.
  • Five PEComas and eight classic angiomyolipomas were positive for phospho-S6.
  • Our observations of frequent deletion of TSC2 and the mTOR signalling pathway provide evidence that the oncogenetic lineage of PEComa, as a distinct TSC2-linked neoplasm, is similar to that of angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / genetics. Biomarkers, Tumor. Kidney Neoplasms / genetics. Tumor Suppressor Proteins / genetics






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