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1. Kamimura K, Oosaki A, Sugahara S, Mori S, Moroda T, Satoh O, Morita T, Kimura K, Kamura T, Nomoto M, Aoyagi Y: Malignant potential of hepatic angiomyolipoma: case report and literature review. Clin J Gastroenterol; 2010 Apr;3(2):104-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant potential of hepatic angiomyolipoma: case report and literature review.
  • Hepatic angiomyolipoma (AML) is known as a rare benign tumor with invasive growth.

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  • (PMID = 26190004.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; HMB-45 / Hepatic angiomyolipoma / Malignant / PEComa / Portal vein thrombosis
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2. Yoshikawa T, Kawamitsu H, Mitchell DG, Ohno Y, Ku Y, Seo Y, Fujii M, Sugimura K: ADC measurement of abdominal organs and lesions using parallel imaging technique. AJR Am J Roentgenol; 2006 Dec;187(6):1521-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In 200 consecutive clinical patients (122 men and 78 women: mean age, 61.9 years), ADCs were calculated for liver (four segments), spleen, pancreas (head, body, tail), gallbladder, renal parenchyma, and back muscle, and then compared to evaluate the reliability of clinical ADC measurements with parallel imaging.
  • There was no significant difference among ADCs of four liver segments (1.50 +/- 0.24 [SD] x 10(-3) mm2/s - 1.56 +/- 0.31 x 10(-3) mm2/s) and between ADCs of the right and left kidneys (2.65 +/- 0.30 x 10(-3) mm2/s, 2.59 +/- 0.33 x 10(-3) mm2/s).
  • Renal ADCs were significantly lower in patients with renal failure (right: 2.15 +/- 0.30 x 10(-3) mm2/s; left: 2.11 +/- 0.25 x 10(-3) mm2/s) than in those without disease (right: 2.67 +/- 0.29 x 10(-3) mm2/s; left: 2.60 +/- 0.32 x 10(-3) mm2/s) (p < 0.005).
  • ADC of renal angiomyolipoma was significantly lower than those of renal cell carcinoma and healthy renal parenchyma (p < 0.0005).
  • [MeSH-major] Diffusion Magnetic Resonance Imaging / methods. Digestive System / pathology. Gastrointestinal Neoplasms / diagnosis

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  • (PMID = 17114546.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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3. Zhang LH, Sun RC, Chen Y: [A case report of epiglottic angiomyolipoma. ]. Zhonghua Bing Li Xue Za Zhi; 2005 Oct;34(10):645
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  • [Title] [A case report of epiglottic angiomyolipoma. ].
  • [MeSH-major] Angiomyolipoma / pathology. Epiglottis. Laryngeal Neoplasms / pathology

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  • (PMID = 17526131.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Actins; 0 / smooth muscle actin, rat; 9001-27-8 / Factor VIII
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4. Heckmann M, Heinrich M, Humke U, Bautz W, Uder M: [Differential diagnosis of focal lesions of the kidney in CT and MRT]. Rontgenpraxis; 2008;56(6):219-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Differential diagnosis of focal lesions of the kidney in CT and MRT].
  • The great majority of renal masses are found incidentally as a result of the use of ultrasonography, computed tomography (CT) and magnetic resonance imaging (MRI).
  • If ultrasonography is not diagnostic CT or MRI should be initiated to differentiate lesions of the kidney that need surgical intervention from those that do not and from those that need follow-up examinations.
  • Cystic renal masses are characterized by using the Bosniak classification, including category IIF.
  • In solid Lesions of the kidney first non-surgical lesions as well as lymphoma, renal infarction and nephritis should be excluded.
  • Identifying fatty components in renal lesions is very important because in angiomyolipoma they are almost always present.
  • Careful evaluation of imaging finding combined with the patient's history should assist the radiologist in making the proper diagnosis or recommending the appropriate treatment in most cases.
  • This article provides a review about renal masses, the imaging methods for their evaluation and their characteristic features at CT and MR imaging.
  • Different lesions are demonstrated like xantogranulomatous pyelonephritis, acute pyelonephritis, renal infarction, lymphoma, angiomyolipoma, renal oncocytoma, cystic lesion and polycystic disease the kidney, echinococcosis, renal cystadenoma, metastases, renal cell carcinoma (RCC), and multiple bilateral RCC in patients with Hippel-Lindau-Syndrome.
  • This article should help to differentiate complex cystic lesions of the kidney by using the Bosniak-classification, especially Bosniak Category IIF.
  • [MeSH-major] Kidney Diseases / diagnosis. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Contrast Media. Diagnosis, Differential. Female. Follow-Up Studies. Gadolinium DTPA. Humans. Kidney Diseases, Cystic / classification. Kidney Diseases, Cystic / diagnosis. Kidney Diseases, Cystic / radiography. Kidney Neoplasms / diagnosis. Kidney Neoplasms / radiography. Lymphoma / diagnosis. Lymphoma / radiography. Male. Polycystic Kidney Diseases / diagnosis. Polycystic Kidney Diseases / radiography. Pyelonephritis / diagnosis. Pyelonephritis / radiography. von Hippel-Lindau Disease / diagnosis. von Hippel-Lindau Disease / radiography

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  • (PMID = 19294868.001).
  • [ISSN] 0035-7820
  • [Journal-full-title] Röntgenpraxis; Zeitschrift für radiologische Technik
  • [ISO-abbreviation] Rontgenpraxis
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
  • [Number-of-references] 24
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5. Chaplin A, Conrad DM, Tatlidil C, Jollimore J, Walsh N, Covert A, Pasternak S: Primary cutaneous PEComa. Am J Dermatopathol; 2010 May;32(3):310-2
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  • They constitute a spectrum of lesions in different organs including angiomyolipoma of the kidney and liver, sugar tumor of the lung, lymphangiomatosis, and lymphangiomyoma.

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  • (PMID = 20139753.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Desmin; 0 / MITF protein, human; 0 / Melanoma-Specific Antigens; 0 / Microphthalmia-Associated Transcription Factor; 0 / Neoplasm Proteins
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6. Marsilia GM, Boscaino A, La Mura A, Ceriello A, De Ritis R: Hepatic angiomyolipoma and intramural small intestinal schwannoma: a coincidence or a relationship? Int J Surg Pathol; 2010 Dec;18(6):537-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiomyolipoma and intramural small intestinal schwannoma: a coincidence or a relationship?
  • We report a case of hepatic angiomyolipoma associated to a small bowel schwannoma in a 40-years old woman.
  • Histologically, hepatic angiomyolipoma showed oncocytic features and scanty adipose tissue, the tumor cells expressed desmin, smooth muscle actin, S-100 protein and HMB45.
  • To the best of our knowledge, no case of hepatic angiomyolipoma has been previously reported in association with intestinal schwannoma.
  • [MeSH-major] Angiomyolipoma / pathology. Jejunal Neoplasms / pathology. Liver Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Neurilemmoma / pathology

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  • (PMID = 19282295.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Woodward PJ, Sohaey R, Kennedy A, Koeller KK: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics; 2005 Jan-Feb;25(1):215-42
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  • Other fetal neoplasms include soft-tissue tumors (both benign and malignant), leukemia, mesenchymal hamartoma of the kidney, and liver tumors (hemangioendothelioma, mesenchymal hamartoma, and hepatoblastoma).
  • [MeSH-major] Fetal Diseases / diagnosis. Neoplasms / diagnosis
  • [MeSH-minor] Brain Neoplasms / diagnosis. Female. Humans. Magnetic Resonance Imaging. Pregnancy. Teratoma / diagnosis. Ultrasonography, Prenatal

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  • (PMID = 15653597.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 82
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8. Hornick JL, Fletcher CD: Sclerosing PEComa: clinicopathologic analysis of a distinctive variant with a predilection for the retroperitoneum. Am J Surg Pathol; 2008 Apr;32(4):493-501
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  • PEComas (tumors showing perivascular epithelioid cell differentiation) are a family of mesenchymal neoplasms that include angiomyolipoma, clear cell "sugar" tumor of the lung, lymphangiomyomatosis, and a group of uncommon lesions that arise in soft tissue, visceral organs, and skin.

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  • (PMID = 18223480.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Calmodulin-Binding Proteins; 0 / Desmin; 0 / MART-1 Antigen; 0 / MITF protein, human; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Microphthalmia-Associated Transcription Factor; 0 / Mucin-1; 0 / Neoplasm Proteins; 0 / S100 Proteins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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9. Yoshikawa M, Hosokawa Y, Takada S, Hayashi Y, Fujimoto K, Hirao Y: [A case of renal perivascular epithelioid cell tumor (PEComa)]. Hinyokika Kiyo; 2010 Mar;56(3):151-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of renal perivascular epithelioid cell tumor (PEComa)].
  • Screening computed tomography showed an enhancing mass of about 9 cm in the right renal upper pole.
  • An open right nephrectomy was performed for the pre-operative diagnosis of renal cell carcinoma.
  • PEComa is a rare tumor, which includes angiomyolipoma and lymphangiomyomatosis.
  • [MeSH-major] Kidney Neoplasms / pathology. Perivascular Epithelioid Cell Neoplasms / pathology

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  • (PMID = 20372042.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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10. Umeoka S, Koyama T, Miki Y, Akai M, Tsutsui K, Togashi K: Pictorial review of tuberous sclerosis in various organs. Radiographics; 2008 Nov-Dec;28(7):e32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The diagnosis is usually established on the basis of diagnostic criteria applied to physical or radiologic findings.
  • Because the classical triad of epilepsy, mental retardation, and adenoma sebaceum is uncommonly seen at clinical examination, radiologic examinations can play an important role in the diagnosis of tuberous sclerosis and in treatment.
  • Cardiac rhabdomyoma, renal angiomyolipoma, and neurologic involvement encompassing cortical or subependymal tubers and white matter abnormalities are the common radiologic findings.
  • The presence of pulmonary lymphangioleiomyomatosis, multifocal micronodular pneumocyte hyperplasia, or multiple renal cysts also raises suspicion of tuberous sclerosis.
  • Familiarity with the clinical and radiologic findings in various organs is crucial in diagnosis and treatment.
  • [MeSH-major] Multiple Organ Failure / diagnosis. Tomography, X-Ray Computed / methods. Tuberous Sclerosis / diagnosis

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  • (PMID = 18772274.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 60
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11. Yang Y, Sun S, Xiao X, Song Y, Cai W, Wang M, Zhang X: Temporary balloon occlusion of inferior vena cava in resection of renal tumor with vena cava thrombus extension. Urology; 2009 Mar;73(3):645-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Temporary balloon occlusion of inferior vena cava in resection of renal tumor with vena cava thrombus extension.
  • OBJECTIVES: To investigate a novel and effective method to occlude the inferior vena cava (IVC) during surgical management of a renal tumor with a tumor thrombus extension into the IVC.
  • METHODS: We retrospectively reviewed the records of 10 patients with renal cell carcinoma or renal angiomyolipoma with tumor thrombus extending into the IVC who had undergone surgical intervention at our institute from May 2005 to May 2006.
  • CONCLUSIONS: Temporary balloon occlusion of the IVC is a simple and reliable technique that decreases the risk of pulmonary embolism and facilitates the resection of renal tumor with levels II and III IVC thrombus.
  • [MeSH-major] Balloon Occlusion. Carcinoma, Renal Cell / secondary. Carcinoma, Renal Cell / surgery. Kidney Neoplasms / pathology. Kidney Neoplasms / surgery. Neoplastic Cells, Circulating. Vena Cava, Inferior

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  • [CommentIn] Eur Urol. 2009 Nov;56(5):883-4 [20965033.001]
  • (PMID = 19167042.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Elsayes KM, Narra VR, Lewis JS Jr, Brown JJ: Magnetic resonance imaging of adrenal angiomyolipoma. J Comput Assist Tomogr; 2005 Jan-Feb;29(1):80-2
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  • [Title] Magnetic resonance imaging of adrenal angiomyolipoma.
  • Angiomyolipoma is a benign mesenchymal neoplasm that typically occurs in the kidney sporadically or in patients with tuberous sclerosis complex.
  • A case of an angiomyolipoma involving the right adrenal gland in a 49-year-old female patient with tuberous sclerosis is reported.
  • Only 2 cases describing adrenal angiomyolipoma were found in the English literature.
  • Neither of these 2 cases was documented in the radiology literature or discussed the MR features of adrenal angiomyolipoma.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Angiomyolipoma / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 15665688.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 19
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13. Lucky MA, Shingler SN, Stephenson RN: A case report of spontaneous rupture of a renal angiomyolipoma in a post-partum 21-year-old patient. Arch Gynecol Obstet; 2009 Oct;280(4):643-5
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  • [Title] A case report of spontaneous rupture of a renal angiomyolipoma in a post-partum 21-year-old patient.
  • INTRODUCTION: Renal angiomyolipomas (AML) are benign tumours containing vascular, smooth muscle and fatty elements.
  • The majority of renal AML run an asymptomatic, benign course.
  • It also demonstrates that further complications of renal angiomyolipoma rupture can arise, emphasising the importance of post treatment vigilance for signs of infection, further haemorrhage and post embolic events.
  • [MeSH-major] Angiomyolipoma / complications. Kidney Neoplasms / complications

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  • (PMID = 19219616.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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14. Kannangai R, Diehl AM, Sicklick J, Rojkind M, Thomas D, Torbenson M: Hepatic angiomyolipoma and hepatic stellate cells share a similar gene expression profile. Hum Pathol; 2005 Apr;36(4):341-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiomyolipoma and hepatic stellate cells share a similar gene expression profile.
  • [MeSH-major] Angiomyolipoma / metabolism. Hepatocytes / metabolism

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  • (PMID = 15891994.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Grant] United States / NIAAA NIH HHS / AA / AA010154; United States / NIAAA NIH HHS / AA / AA10541; United States / NIDA NIH HHS / DA / DA016078; United States / NIDA NIH HHS / DA / DA016370; United States / NIDDK NIH HHS / DK / DK53792
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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15. Dabbeche C, Chaker M, Chemali R, Perot V, El Hajj L, Ferriere JM, Ballanger P, Chabbert V, Cimpean A, Otal P, Huyghe E, Grenier N, Joffre F: [Role of embolization in renal angiomyolipomas]. J Radiol; 2006 Dec;87(12 Pt 1):1859-67
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Role of embolization in renal angiomyolipomas].
  • OBJECTIVE: The purpose of this study is to present the role of embolization in the treatment of renal angiomyolipoma (AML) in cases of hemorrhage and to prevent bleeding.
  • [MeSH-major] Angiomyolipoma / complications. Embolization, Therapeutic. Hemorrhage / etiology. Hemorrhage / therapy. Kidney Neoplasms / complications

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  • (PMID = 17213770.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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16. Patil AR, Chandra R, Gupta A, Thukral BB: Giant aneurysm formation in sporadic renal angiomyolipoma. J Radiol Case Rep; 2010;4(6):21-7
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  • [Title] Giant aneurysm formation in sporadic renal angiomyolipoma.
  • Angiomyolipomas are the most common mesenchymal renal neoplasms.
  • Two types have been described: (i) sporadic angiomyolipoma and (ii) angiomyolipoma associated with tuberous sclerosis.
  • We report a rare case of aneurysm formation in a sporadic angiomyolipoma.

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  • (PMID = 22470737.001).
  • [ISSN] 1943-0922
  • [Journal-full-title] Journal of radiology case reports
  • [ISO-abbreviation] J Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3303414
  • [Keywords] NOTNLM ; Aneurysm / Angiomyolipoma / Computed Tomography / Tuberous Sclerosis complex
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17. Aguilera Tubet C, Portillo Martín JA, Gutiérrez Baños JL, Ruiz Izquierdo F, Ballestero Diego R, Zubillaga Guerrero S: [Emergency conservative surgery on a unique kidney with broken multiple angiomyolipoma]. Actas Urol Esp; 2007 Feb;31(2):164-7
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  • [Title] [Emergency conservative surgery on a unique kidney with broken multiple angiomyolipoma].
  • [Transliterated title] Cirugía conservadora de urgencia en monorrena por rotura de angiomiolipoma múltiple.
  • A case of retroperitoneal hemorrhage due to the rupture of a multiple angiomyolipoma in a female with a unique kidney is described.
  • [MeSH-major] Angiomyolipoma / complications. Angiomyolipoma / surgery. Emergency Treatment. Kidney / abnormalities. Kidney Neoplasms / complications. Kidney Neoplasms / surgery

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  • (PMID = 17645098.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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18. Okoń K: Pathology of renal tumors in adults. Molecular biology, histopathological diagnosis and prognosis. Pol J Pathol; 2008;59(3):129-76
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  • [Title] Pathology of renal tumors in adults. Molecular biology, histopathological diagnosis and prognosis.
  • Malignant renal tumors constitute 3% of human cancers, although their frequency differs greatly in various areas.
  • Since the fifties, the incidence of renal cancers has been increasing, but at the some time the prognosis has been improving.
  • In particular, in the last years, several new treatment modalities have been introduced, relying on the understanding of renal cancer biology.
  • The identified etiological factors include smoking, increased body mass, dietary factors and chronic renal disease.
  • There are several renal tumor types differing in morphology, molecular genetics and biology.
  • Differential diagnosis of these tumors is particularly difficult and may require extensive immunohistochemical and molecular studies.
  • Some renal tumors have been described or recognized only relatively recently; these newer entities include multilocular cystic clear cell carcinoma, spindle cell papillary mucinous carcinoma, tubulocystic carcinoma, renal epithelial and stromal tumor, epithelioid and oncocytic angiomyolipoma.
  • The improved prognosis in renal cancer depends on earlier detection, but also on refinement of therapeutic methods.
  • Renal carcinoma is notorious for its low sensitivity to chemotherapy and radiotherapy.
  • With this progress, perfect understanding of renal tumor biology and exact histological diagnosis have become of prime practical importance.
  • [MeSH-major] Kidney Neoplasms


19. Shimada S, Harada H, Ishizawa K, Hirose T: Retroperitoneal lipomatous angiomyolipoma associated with amyloid deposition masquerading as well-differentiated liposarcoma. Pathol Int; 2006 Oct;56(10):638-41
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  • [Title] Retroperitoneal lipomatous angiomyolipoma associated with amyloid deposition masquerading as well-differentiated liposarcoma.
  • Reported herein is a case of retroperitoneal angiomyolipoma associated with amyloid deposition, masquerading as well-differentiated liposarcoma.
  • Therefore, the tumor was diagnosed as lipomatous angiomyolipoma.
  • After the diagnosis, it was found that the patient had multiple myeloma and cardiac amyloidosis, suggesting that the amyloid deposition within the tumor was a complication of the myeloma.
  • Lipomatous angiomyolipoma may be a diagnostic pitfall of retroperitoneal lipomatous tumors.
  • [MeSH-major] Amyloid / metabolism. Angiomyolipoma / diagnosis. Angiomyolipoma / metabolism. Liposarcoma / diagnosis. Liposarcoma / metabolism. Retroperitoneal Neoplasms / diagnosis. Retroperitoneal Neoplasms / metabolism
  • [MeSH-minor] Aged. Cyclin-Dependent Kinase 4 / genetics. Cyclin-Dependent Kinase 4 / metabolism. Diagnosis, Differential. Female. Gene Expression Regulation, Enzymologic. Gene Expression Regulation, Neoplastic. Humans. Proto-Oncogene Proteins c-mdm2 / genetics. Proto-Oncogene Proteins c-mdm2 / metabolism

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  • (PMID = 16984623.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Amyloid; EC 2.7.11.22 / Cyclin-Dependent Kinase 4; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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20. Magro G, Lanzafame S: Sporadic subcutaneous angiomyolipoma with expression of estrogen and progesterone receptors. Virchows Arch; 2007 Jan;450(1):123-5
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  • [Title] Sporadic subcutaneous angiomyolipoma with expression of estrogen and progesterone receptors.
  • [MeSH-major] Angiomyolipoma / pathology. Receptors, Estrogen / analysis. Receptors, Progesterone / analysis. Skin Neoplasms / pathology

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  • [Cites] Chest. 2000 Jan;117(1):25-30 [10631194.001]
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  • (PMID = 17124601.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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21. Sugimoto T, Morita Y, Kashiwagi A: Spontaneous hemorrhage from renal angiomyolipoma presenting with fever of unknown origin. Intern Med; 2007;46(11):793-4
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  • [Title] Spontaneous hemorrhage from renal angiomyolipoma presenting with fever of unknown origin.
  • [MeSH-major] Angiomyolipoma / complications. Fever of Unknown Origin / etiology. Hematoma / complications. Kidney Neoplasms / complications

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  • (PMID = 17541239.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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22. Li T, Fan J, Qin LX, Zhou J, Sun HC, Wang L, Ye QH, Qiu SJ, Tang ZY: [A clinicopathologic study of hepatic angiomyolipoma]. Zhonghua Wai Ke Za Zhi; 2009 Oct 15;47(20):1536-9
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  • [Title] [A clinicopathologic study of hepatic angiomyolipoma].
  • OBJECTIVE: To investigate the clinicopathologic features, diagnosis and treatment of hepatic angiomyolipoma (HAML).
  • Definitive diagnosis of HAML depends on the pathohistological findings and HMB-45 positive myoid cell is an important diagnostic marker.
  • [MeSH-major] Angiomyolipoma / pathology. Liver Neoplasms / pathology

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  • (PMID = 20092740.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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23. Takahashi K, Yano Y, Miyata Y, Terai T: [Anesthetic management of a patient with pulmonary tuberous sclerosis complicated with renal angiomyolipoma]. Masui; 2009 May;58(5):641-4
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  • [Title] [Anesthetic management of a patient with pulmonary tuberous sclerosis complicated with renal angiomyolipoma].
  • She suffered from tuberous sclerosis and was complicated with lymphangioleiomyomatosis and renal angiomyolipoma.
  • This case was managed carefully to avoid pneumothorax and acute bleeding from renal angiomyolipoma.
  • [MeSH-major] Anesthesia, Epidural. Anesthesia, Spinal. Angiomyolipoma / complications. Hysterectomy. Kidney Neoplasms / complications. Lymphangioleiomyomatosis / complications. Tuberous Sclerosis / complications


24. Takahara M, Miyake Y, Matsumoto K, Kawai D, Kaji E, Toyokawa T, Nakatsu M, Ando M, Hirohata M: A case of hepatic angiomyolipoma difficult to distinguish from hepatocellular carcinoma. World J Gastroenterol; 2009 Jun 21;15(23):2930-2
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  • [Title] A case of hepatic angiomyolipoma difficult to distinguish from hepatocellular carcinoma.
  • We report a case of hepatic angiomyolipoma with uncommon clinical features.
  • In cases with uncommon features of angiomyolipoma, it is quite difficult to distinguish angiomyolipoma from hepatocellular carcinoma.
  • [MeSH-major] Angiomyolipoma. Carcinoma, Hepatocellular. Liver Neoplasms

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  • (PMID = 19533821.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2699017
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25. Langen HJ, Markert K, Griesser H: [CT-x ray of a renal cell carcinoma reveals an angiomyolipoma]. Rofo; 2007 Apr;179(4):425-7
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  • [Title] [CT-x ray of a renal cell carcinoma reveals an angiomyolipoma].
  • [MeSH-major] Angiomyolipoma / radiography. Angiomyolipoma / surgery. Carcinoma, Renal Cell / radiography. Carcinoma, Renal Cell / surgery. Kidney Neoplasms / radiography. Kidney Neoplasms / surgery

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  • (PMID = 17377877.001).
  • [ISSN] 1438-9029
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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26. López Fernández A, Lacasta García JD, Puig Giro R, Vicente de Vera P: [Kidney angiomyolipoma as aetiology of haemorragic shock]. Actas Urol Esp; 2008 Sep;32(8):855-7
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  • [Title] [Kidney angiomyolipoma as aetiology of haemorragic shock].
  • [Transliterated title] Angimiolipoma renal como causa de shock hemorrágico agudo.
  • This is a case of retroperitoneal hematoma and hypovolemic shock as a presentation of renal angiomyolipoma, a rarely benign and asymptomatic tumor.
  • Although that kind of tumor needs non-aggressive treatment, as a general rule, because of the size and severity of the following symptoms, the patient has been submitted to a selective embolization of the renal mass when he was hemodinamically stabilized.
  • The evolution was favorable; it was not necessary to do more aggressive surgical handling neither to urgently remove the angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / complications. Kidney Neoplasms / complications. Shock, Hemorrhagic / etiology

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  • (PMID = 19013987.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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27. Corso R, Carrafiello G, Rampoldi A, Leni D, Ticca C, Vercelli R, Vanzulli A: Pseudoaneurysm after spontaneous rupture of renal angiomyolipoma in tuberous sclerosis: successful treatment with percutaneous thrombin injection. Cardiovasc Intervent Radiol; 2005 Mar-Apr;28(2):262-4
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  • [Title] Pseudoaneurysm after spontaneous rupture of renal angiomyolipoma in tuberous sclerosis: successful treatment with percutaneous thrombin injection.
  • We report a case of a large perinephric pseudoaneurysm due to spontaneous rupture of renal angiomyolipoma, occluded by percutaneous thrombin injection under ultrasound guidance in a young woman affected by tuberous sclerosis.
  • [MeSH-major] Aneurysm, False / etiology. Angiomyolipoma / complications. Embolization, Therapeutic / methods. Hemostatics / therapeutic use. Kidney Neoplasms / complications. Thrombin / therapeutic use. Tuberous Sclerosis / complications

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  • (PMID = 15719182.001).
  • [ISSN] 0174-1551
  • [Journal-full-title] Cardiovascular and interventional radiology
  • [ISO-abbreviation] Cardiovasc Intervent Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hemostatics; EC 3.4.21.5 / Thrombin
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28. Coulibaly B, Bouvier C, Payan MJ, Thomas P: Recurrent dedifferentiated liposarcoma of mediastinum involving lung and pleura. Interact Cardiovasc Thorac Surg; 2009 Oct;9(4):741-2
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  • A woman who complained of dyspnea showed on imaging features a bulky posterior mediastinal mass which was completely excised and initially misdiagnosed as an angiomyolipoma.

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  • (PMID = 19589790.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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29. Acikalin MF, Tel N, Oner U, Pasaoglu O, Dönmez T: Epithelioid angiomyolipoma of the kidney. Int J Urol; 2005 Feb;12(2):204-7
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  • [Title] Epithelioid angiomyolipoma of the kidney.
  • Epithelioid angiomyolipoma is a recently recognized variant of angiomyolipoma, which is characterized by the presence of polygonal cells with densely eosinophilic cytoplasm and varying degrees of nuclear atypia.
  • Only a relatively small number of cases of epithelioid angiomyolipoma of the kidney have been reported in the literature.
  • We report a case of epithelioid angiomyolipoma of the kidney that occurred in a 38-year-old woman.
  • [MeSH-major] Angiomyolipoma / pathology. Epithelioid Cells / pathology. Kidney Neoplasms / pathology

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  • (PMID = 15733117.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Antigens, Neoplasm; 0 / CD68 antigen, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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30. Meng YH, Pei F, Lu P, Yu JY, Zheng J: [Epithelioid angiomyolipoma of kidney: clinicopathologic study of two cases and review of literature]. Zhonghua Bing Li Xue Za Zhi; 2007 Jan;36(1):19-23
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  • [Title] [Epithelioid angiomyolipoma of kidney: clinicopathologic study of two cases and review of literature].
  • OBJECTIVE: To study the histopathologic features, differential diagnosis and prognosis of epithelioid angiomyolipoma (EAML) of kidney.
  • METHODS: Two cases of EAML (including one case with recurrence) of kidney were retrieved from the archival files of Departments of Pathology, Navy General Hospital of PLA and Health Science Center of Peking University.
  • The renal hilar lymph nodes were also involved by tumor cells.
  • Perivascular cellular arrangement, focal features of otherwise classic angiomyolipoma, as well as coexpression of HMB-45 and smooth muscle actin are clues to the correct diagnosis.
  • On the other hand, the presence of lymph node involvement and even tumor emboli in renal veins may represent multifocaltumorigenicity rather than true malignancy.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, Neoplasm / metabolism. Diagnosis, Differential. Epithelioid Cells / pathology. Epithelioid Cells / ultrastructure. Humans. Immunohistochemistry. Kidney / pathology. Kidney / ultrastructure. Male. Melanoma-Specific Antigens. Microscopy, Electron. Neoplasm Proteins / metabolism

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  • (PMID = 17374233.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
  • [Number-of-references] 15
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31. Inahara M, Takei K, Naito H, Eguchi M: [Extrarenal angiomyolipoma with spontaneous rupture: a case report]. Hinyokika Kiyo; 2008 Jul;54(7):485-8
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  • [Title] [Extrarenal angiomyolipoma with spontaneous rupture: a case report].
  • We present a very rare case of retroperitoneal extrarenal angiomyolipoma (AML) with spontaneous rupture.
  • We suspected right renal AML with rupture by imaging analysis, but the diagnosis was extrarenal AML by surgery and pathological examination.
  • [MeSH-major] Angiomyolipoma / pathology. Angiomyolipoma / surgery. Kidney Neoplasms / pathology. Kidney Neoplasms / surgery. Retroperitoneal Neoplasms / pathology. Retroperitoneal Neoplasms / surgery

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  • (PMID = 18697493.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 17
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32. Phillips CK, Lepor H: Spontaneous retroperitoneal hemorrhage caused by segmental arterial mediolysis. Rev Urol; 2006;8(1):36-40
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  • Spontaneous retroperitoneal hemorrhage can be caused by tumors, such as renal cell carcinoma and angiomyolipoma; polyarteritis nodosa; and nephritis.
  • Although computed tomography is used for the diagnosis of spontaneous retroperitoneal hemorrhage, it can miss segmental arterial mediolysis as the cause of the hemorrhage.
  • The diagnosis of segmental arterial mediolysis as a cause of spontaneous retroperitoneal hemorrhage requires angiography, with pathologic confirmation for a definitive diagnosis.

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  • (PMID = 16985559.001).
  • [ISSN] 1523-6161
  • [Journal-full-title] Reviews in urology
  • [ISO-abbreviation] Rev Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1471764
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33. Lu HC, Chau GY, Su CW: Clinical challenges and images in GI. Diagnosis: Hepatic angiomyolipoma mimicking hepatocellular carcinoma. Gastroenterology; 2009 Apr;136(4):1169, 1464
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  • [Title] Clinical challenges and images in GI. Diagnosis: Hepatic angiomyolipoma mimicking hepatocellular carcinoma.
  • [MeSH-major] Angiomyolipoma / diagnosis. Carcinoma, Hepatocellular / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Angiography. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Hepatic Artery / radiography. Humans. Mesenteric Arteries / radiography. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 19254682.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Ricketts R, Tamboli P, Czerniak B, Guo CC: Tumor-to-tumor metastasis: report of 2 cases of metastatic carcinoma to angiomyolipoma of the kidney. Arch Pathol Lab Med; 2008 Jun;132(6):1016-20
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  • [Title] Tumor-to-tumor metastasis: report of 2 cases of metastatic carcinoma to angiomyolipoma of the kidney.
  • Renal cell carcinoma is the most common recipient of tumor-to-tumor metastasis in malignant tumors.
  • However, renal angiomyolipoma has not been reported to be a recipient.
  • Here we report 2 cases of tumor-to-tumor metastasis to renal angiomyolipoma.
  • The donor tumors showed morphologic features that did not easily fit into renal angiomyolipoma, and they also demonstrated patterns of immunoreactivity consistent with the primary tumors rather than with renal angiomyolipoma.
  • To our knowledge, these are the first reported cases of tumor-to-tumor metastasis to renal angiomyolipoma.
  • An awareness of this phenomenon is important to avoid an incorrect diagnosis when encountering unusual morphologic features in renal angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / pathology. Carcinoma / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 18517262.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Huo L, Sugimura J, Tretiakova MS, Patton KT, Gupta R, Popov B, Laskin WB, Yeldandi A, Teh BT, Yang XJ: C-kit expression in renal oncocytomas and chromophobe renal cell carcinomas. Hum Pathol; 2005 Mar;36(3):262-8
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  • [Title] C-kit expression in renal oncocytomas and chromophobe renal cell carcinomas.
  • Recently, KIT has been reported to be a marker for chromophobe renal cell carcinoma (RCC) and renal angiomyolipoma.
  • However, expression of this molecule has not been adequately studied in other renal tumors, particularly oncocytoma, which may morphologically resemble chromophobe RCC.
  • In this study, we analyzed c- kit messenger RNA (mRNA) levels in 17 chromophobe RCCs and 20 renal oncocytomas obtained from complementary DNA (cDNA) microarrays.
  • Furthermore, comprehensive immunohistochemical analysis of KIT protein using a monoclonal antibody was performed in 226 renal tumors including chromophobe RCC (n=40), oncocytoma (n=41), clear-cell RCC (n=40), renal angiomyolipoma (n=29), and papillary RCC (n=21) on tissue microarrays (TMAs) and was compared with immunostaining results from 25 chromophobe RCCs and 30 oncocytomas using standard sections.
  • The average increase of mRNA compared with normal kidney tissue was 7.4-fold for chromophobe RCCs and 7.4-fold for oncocytomas.
  • Immunohistochemical expression of KIT was found in most chromophobe RCCs (95% in TMAs and 96% in conventional sections) and oncocytomas (88% in TMAs and 100% in conventional sections) but was infrequently observed in renal angiomyolipomas (17%), papillary RCCs (5%), and clear-cell RCCs (3%).
  • Furthermore, the average KIT immunoreactivity in TMAs was stronger in chromophobe RCC (1.93) and oncocytoma (2.07) than in other subtypes of renal tumors tested, including angiomyolipomas (0.17), papillary RCCs (0.05), and clear-cell RCCs (0.03).
  • In contrast, immunohistochemical expression of KIT was not detected in most other types of renal cell tumors evaluated.
  • The differential expression of c- kit in these renal tumors may have diagnostic and therapeutic implications.
  • [MeSH-major] Adenoma, Oxyphilic / genetics. Carcinoma, Renal Cell / genetics. Gene Expression. Kidney Neoplasms / genetics. Proto-Oncogene Proteins c-kit / genetics. RNA, Messenger / analysis

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  • (PMID = 15791570.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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36. El-Hashemite N, Kwiatkowski DJ: Interferon-gamma-Jak-Stat signaling in pulmonary lymphangioleiomyomatosis and renal angiomyolipoma: a potential therapeutic target. Am J Respir Cell Mol Biol; 2005 Sep;33(3):227-30
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  • [Title] Interferon-gamma-Jak-Stat signaling in pulmonary lymphangioleiomyomatosis and renal angiomyolipoma: a potential therapeutic target.
  • Pulmonary lymphangioleiomyomatosis (LAM) and renal angiomyolipoma (AML) are proliferative lesions that occur in sporadic patients, and at much higher frequency in patients with tuberous sclerosis (TSC).

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  • [Cites] Hum Genet. 2000 Aug;107(2):97-114 [11030407.001]
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  • (PMID = 15994429.001).
  • [ISSN] 1044-1549
  • [Journal-full-title] American journal of respiratory cell and molecular biology
  • [ISO-abbreviation] Am. J. Respir. Cell Mol. Biol.
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / NS 31535
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Jak1 protein, mouse; 0 / Proto-Oncogene Proteins; 0 / Repressor Proteins; 0 / STAT1 Transcription Factor; 0 / STAT1 protein, human; 0 / STAT3 Transcription Factor; 0 / STAT3 protein, human; 0 / Stat1 protein, mouse; 0 / Stat3 protein, mouse; 0 / Trans-Activators; 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein; 82115-62-6 / Interferon-gamma; EC 2.7.010.2 / JAK1 protein, human; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.2 / JAK2 protein, human; EC 2.7.10.2 / Jak2 protein, mouse; EC 2.7.10.2 / Janus Kinase 1; EC 2.7.10.2 / Janus Kinase 2
  • [Other-IDs] NLM/ PMC2715313
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37. Galliot I, Albouy B, Houlle S, Secco M, Gobet F, Pfister C: [Renal angiomyolipoma with inferior vena cava extension]. Prog Urol; 2010 May;20(5):382-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Renal angiomyolipoma with inferior vena cava extension].
  • [Transliterated title] Angiomyolipome renal à extension veineuse cave inférieure.
  • Angiomyolipoma is generally a benign and noninvasive tumor.
  • We report a case of angiomyolipoma with tumor thrombus from the renal vein into the inferior vena cava suggesting a malignant disease.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology. Neoplastic Cells, Circulating. Vena Cava, Inferior

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  • [Copyright] Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20471584.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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38. Kontos S, Politis V, Fokitis I, Lefakis G, Koritsiadis G, Simaioforidis V, Kachrilas S, Chatziplis E, Koritsiadis S: Rapture of renal angiomyolipoma during pregnancy: a case report. Cases J; 2008;1(1):245
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  • [Title] Rapture of renal angiomyolipoma during pregnancy: a case report.
  • INTRODUCTION: Rapture of a renal angiomyolipoma and massive retroperitoneal hemorrhage, during pregnancy is rare and occasionally fatal.
  • The ultrasound and MRI (Magnetic resonance imaging) scan showed a 7 x 7 x 5 cm mass suggestive of angiomyolipoma in the right kidney, with evidence of retroperitoneal bleeding right perirenal and intrarenal haematoma.
  • The histological study of the resected mass revealed the presence of angiomyolipoma.
  • Angiomyolipoma with spontaneous bleeding during pregnancy is a dangerous condition that may cause mortality in the mother and fetus, but elective, simultaneous cesarean section and radical nephrectomy can be performed.

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  • (PMID = 18928528.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2576180
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39. Brodkiewicz A, Marciniak H, Szychot E, Walecka A, Peregud-Pogorzelski J: Angiomyolipomas, renal manifestation of tuberous sclerosis complex in 17-year-old boy--a case report. Ann Acad Med Stetin; 2008;54(2):160-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomyolipomas, renal manifestation of tuberous sclerosis complex in 17-year-old boy--a case report.
  • INTRODUCTION: Tuberous sclerosis complex (TSC) is a genetic disorder characterised by lesions affecting brain, skin, eyes and internal organs--kidneys, heart, liver and lungs.
  • Renal involvement in individuals with TSC is common and potentially serious, includes angiomyolipomas and cystic lesions.
  • There may also be an increased risk of renal cell carcinoma.
  • CASE REPORT: A case of 17-year-old boy with delayed diagnosis of tuberous sclerosis complex with angiomyolipomas and cysts of the kidneys has been described.
  • CONCLUSION: The authors would like to underlina a very rare incidence of tuberous sclerosis complex and associated renal angiomyolipomas in children, the possibility to maintain normal kidney function for prolonged time despite intensified renal pathology, the need for periodic abdominal imaging and significantly delayed diagnosis in the described case.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Tuberous Sclerosis / diagnosis
  • [MeSH-minor] Adolescent. Carcinoma, Renal Cell / diagnosis. Diagnosis, Differential. Humans. Male. Polycystic Kidney Diseases / complications. Polycystic Kidney Diseases / diagnosis


40. Buĭlov VM, Teodorovich OV, Borisanov AV: [Spiral computed tomography in the differential diagnosis of renal angiomyolipoma with the minimum amount of fatty tissue and renal-cell carcinoma with fatty inclusions]. Vestn Rentgenol Radiol; 2005 Jul-Aug;(4):42-6
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  • [Title] [Spiral computed tomography in the differential diagnosis of renal angiomyolipoma with the minimum amount of fatty tissue and renal-cell carcinoma with fatty inclusions].
  • [MeSH-major] Angiomyolipoma / radiography. Carcinoma, Renal Cell / radiography. Kidney Neoplasms / radiography. Neoplasms, Multiple Primary / radiography. Tomography, Spiral Computed
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Nephrectomy

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  • (PMID = 16353901.001).
  • [ISSN] 0042-4676
  • [Journal-full-title] Vestnik rentgenologii i radiologii
  • [ISO-abbreviation] Vestn Rentgenol Radiol
  • [Language] rus
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Russia (Federation)
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41. Sutter R, Boehler A, Willmann JK: Adrenal angiomyolipoma in lymphangioleiomyomatosis. Eur Radiol; 2007 Feb;17(2):565-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adrenal angiomyolipoma in lymphangioleiomyomatosis.
  • [MeSH-major] Adrenal Gland Neoplasms / secondary. Angiomyolipoma / pathology. Lymphangioleiomyomatosis / pathology

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  • [Cites] Radiology. 2000 Jul;216(1):147-53 [10887241.001]
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  • (PMID = 16586050.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
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42. Shi H, Cao D, Wei L, Sun L, Guo A: Inflammatory angiomyolipomas of the liver: a clinicopathologic and immunohistochemical analysis of 5 cases. Ann Diagn Pathol; 2010 Aug;14(4):240-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hepatic angiomyolipoma (AML) may demonstrate a marked histologic diversity.
  • [MeSH-major] Angiomyolipoma / pathology. Liver Neoplasms / pathology

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20637427.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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43. Quek ML, Soni RA, Hsu J, Skinner DG: Renal epithelioid angiomyolipoma associated with hyperprolactinemia. Urology; 2005 Apr;65(4):797
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  • [Title] Renal epithelioid angiomyolipoma associated with hyperprolactinemia.
  • We report a unique case of a 42-year-old woman with a renal epithelioid angiomyolipoma associated with elevated serum prolactin levels and presenting with galactorrhea.
  • Magnetic resonance imaging of the brain showed no pituitary abnormality, and abdominal imaging demonstrated a large right renal mass.
  • Pathologic analysis of the radical nephrectomy specimen revealed an epithelioid angiomyolipoma.
  • To our knowledge, the association between epithelioid angiomyolipoma and hyperprolactinemia has never before been reported.
  • [MeSH-major] Angiomyolipoma / complications. Hyperprolactinemia / etiology. Kidney Neoplasms / complications


44. Takanami K, Kaneta T, Hitachi S, Yamada T, Ishida K, Rikiyama T, Katayose Y, Unno M, Yamada S, Takahashi S: F-18 FDG PET/CT findings in two patients with hepatic angiomyolipoma with and without intratumoral hemorrhage. Clin Nucl Med; 2010 Jan;35(1):18-21
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  • [Title] F-18 FDG PET/CT findings in two patients with hepatic angiomyolipoma with and without intratumoral hemorrhage.
  • [MeSH-major] Angiomyolipoma / diagnosis. Fluorodeoxyglucose F18. Hemorrhage / radionuclide imaging. Liver Neoplasms / diagnosis. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 20026966.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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45. Remzi M, Memarsadeghi M: [Small incidental renal tumors. Evaluation and biological parameters]. Urologe A; 2007 May;46(5):478, 480-4
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  • [Title] [Small incidental renal tumors. Evaluation and biological parameters].
  • Of 287 patients with small (<or=4 cm) renal tumors, 19.5% had a benign lesion and thus harmless.
  • All others were renal cell cancers; 4.9% of tumors were detected because of metastases and consecutively treated.
  • With the exception of the typical angiomyolipoma, determination of dignity for small solid kidney lesions is unreliable even with modern imaging.
  • Percutaneous renal mass biopsy has an accuracy of over 90% for detecting benign lesions and can influence therapeutic decisions, especially in patients with higher surgical risk.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biopsy, Needle. Female. Humans. Incidental Findings. Kidney / pathology. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Survival Rate

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  • (PMID = 17447049.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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46. Yu ZX, Xia GP, Hu WH, Chen W, Li XB, Chen HD, Lin LZ, Deng ZX, Cai B, Weng ZL: [Etiology, diagnosis and management of spontaneous per renal hemorrhage]. Zhonghua Yi Xue Za Zhi; 2006 Jan 3;86(1):39-41
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  • [Title] [Etiology, diagnosis and management of spontaneous per renal hemorrhage].
  • OBJECTIVE: To investigate the etiology, diagnosis, and management of spontaneous perirenal hemorrhage (SPH).
  • METHODS: The clinical data of 35 patients, 10 males and 12 females, aged 35.9 (12-77), with the diagnosis of SPH, without history of trauma, anticoagulant use, dialysis, and renal transplantation, were analyzed.
  • RESULTS: The underlying disease of SPH included angiomyolipoma (18 cases), renal cell carcinoma (7 cases), kidney cyst (2 cases), renal artery aneurysm (3 cases), rupture of renal artery aneurysm accompanied with pregnancy (2 cases), renal pheochromocytoma (3 cases 2 of which accompanied with pregnancy), congenital stricture of pelvic ureter junction (1 case), and liver cancer (1 case).
  • The most common underlying diseases were nephrogenic (96%) with angiomyolipoma ranking first (54%) followed by renal cell carcinoma (21%).
  • CT helped in diagnosis of 34 cases.
  • CONCLUSION: The most common causes of SPH is renal neoplasms more than 50% of which are benign.
  • Renal artery aneurysm and pheochromocytoma tend to rupture during pregnancy.
  • CT is the first method of choice in diagnosis.
  • [MeSH-major] Hemorrhage / radiography. Hemorrhage / therapy. Kidney Diseases / radiography. Kidney Diseases / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aneurysm / complications. Angiography, Digital Subtraction. Angiomyolipoma / complications. Anticoagulants / therapeutic use. Child. Female. Humans. Kidney Neoplasms / complications. Kidney Transplantation. Male. Middle Aged. Pregnancy. Renal Artery / pathology. Renal Dialysis. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16606534.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Anticoagulants
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47. Azurmendi Arin I, Llarena Ibarguren R, García-Olaverri Rodríguez J, Olano Grasa I, Cantón Aller E, Pertusa Peña C: [Epithelioid renal angiomyolipoma]. Arch Esp Urol; 2008 May;61(4):540-3
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  • [Title] [Epithelioid renal angiomyolipoma].
  • [Transliterated title] Angiomiolipoma epitelioide renal.
  • OBJECTIVE: To issue the existence of a variety of angiomyolipoma, named epithelioid, with different histological and clinic properties.
  • METHODS: We report the case of a 17 year old female, with Bourneville's disease, who was discovered to have a solid renal mass suggestive of carcinoma in a control CT scan, adjacent to other smaller masses identified as angiomyolipomas.
  • RESULTS: After several tumorectomies, the suspicious mass, 4 cm in size, was diagnosed as epithelioid angiomyolipoma, with immunohistochemical confirmation of capacity for HMB45, and negative vimentin and keratin.
  • CONCLUSIONS: Despite the possibility of coexistence of adenocarcinoma and angiomyolipoma, the existence of an epithelioid variety cannot be discarded, mainly in patients with phakomatosis.
  • The indications for surgery are the same than for the rest of renal masses.
  • Nevertheless, follow-up criteria must be stricter due to the possibility of torpid outcome in terms of dissemination of this infrequent variety of angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis

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  • (PMID = 18592777.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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48. Garcia-Covarrubias L, McGee J, Landes J, Florman SS, Slakey DP: Cadaveric kidney transplant complicated by rupture of native kidney angiomyolipoma: a case report and review of the literature. Am Surg; 2005 Apr;71(4):286-8
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  • [Title] Cadaveric kidney transplant complicated by rupture of native kidney angiomyolipoma: a case report and review of the literature.
  • Kidneys with angiomyolipomas have been used for transplantation, but we are unaware of postoperative hemorrhage from a native kidney angiomyolipoma.
  • A 49-year-old male who underwent a cadaveric renal transplant complicated by postoperative hemorrhage from a native kidney angiomyolipoma is presented.
  • [MeSH-major] Angiomyolipoma / etiology. Kidney Neoplasms / etiology. Kidney Transplantation / adverse effects. Postoperative Hemorrhage / etiology
  • [MeSH-minor] Adult. Angiography. Cadaver. Diagnosis, Differential. Embolization, Therapeutic. Follow-Up Studies. Humans. Hypertension / complications. Kidney Failure, Chronic / etiology. Kidney Failure, Chronic / surgery. Male. Rupture, Spontaneous. Tomography, X-Ray Computed


49. Byrd GF, Lawatsch EJ, Mesrobian HG, Begun F, Langenstroer P: Laparoscopic cryoablation of renal angiomyolipoma. J Urol; 2006 Oct;176(4 Pt 1):1512-6; discussion 1516
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  • [Title] Laparoscopic cryoablation of renal angiomyolipoma.
  • PURPOSE: Angiomyolipomas are rare benign renal tumors which occasionally require intervention.
  • Preservation of renal function is essential when treating renal angiomyolipoma in patients with multiple or bilateral lesions.
  • We report on the first series of patients with renal angiomyolipoma treated with laparoscopic cryoablation.
  • MATERIALS AND METHODS: Seven patients with pathologically confirmed renal angiomyolipoma underwent laparoscopic cryoablation.
  • Six patients were female, and 2 patients had associated tuberous sclerosis and multiple bilateral angiomyolipoma.
  • Renal function was preserved, with mean preoperative and postoperative creatinine 0.83 (range 0.6 to 1.6) and 0.91 (range 0.7 to 1.8), respectively.
  • CONCLUSIONS: Laparoscopic cryoablation is a safe and feasible minimally invasive, nephron sparing alternative for the treatment of angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / surgery. Cryosurgery. Kidney Neoplasms / surgery. Laparoscopy

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  • (PMID = 16952669.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. Ramírez Daniel L, García Sabela L, Rey Jorge R, Calvo Antonio O: [Retroperitoneal angiomyolipoma: review of the literature and report of a new case]. Actas Urol Esp; 2010 Oct;34(9):815-7
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  • [Title] [Retroperitoneal angiomyolipoma: review of the literature and report of a new case].
  • [Transliterated title] Angiomiolipoma retroperitoneal: revisión de la literatura y reporte de un nuevo caso.
  • [MeSH-major] Angiomyolipoma. Puerperal Disorders. Retroperitoneal Neoplasms

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  • (PMID = 20843462.001).
  • [ISSN] 1699-7980
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] Spain
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51. Takamura K, Miyake H, Fujii M, Nishi M, Tashiro S, Shimada M: Multiple hepatic angiomyolipomas with a solitary omental angiomyolipoma. J Med Invest; 2005 Aug;52(3-4):218-22
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  • [Title] Multiple hepatic angiomyolipomas with a solitary omental angiomyolipoma.
  • Angiomyolipoma (AML) is a rare benign tumor that occurs most commonly in the kidney.
  • Furthermore, extra renal or hepatic AML are rarely found.
  • At the age of 23, the patient underwent right nephrectomy and enucleation of a left renal tumor because of bilateral AMLs.
  • Histologically it was an epithelioid AML and positive for the melanogenesis-related marker HMB-45, the same as the earlier right renal tumor.
  • [MeSH-major] Angiomyolipoma / pathology. Liver Neoplasms / pathology. Omentum. Peritoneal Neoplasms / pathology

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  • (PMID = 16167542.001).
  • [ISSN] 1343-1420
  • [Journal-full-title] The journal of medical investigation : JMI
  • [ISO-abbreviation] J. Med. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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52. Morton JM, McLean C, Booth SS, Snell GI, Whitford HM: Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment. J Heart Lung Transplant; 2008 Apr;27(4):462-5
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  • [Title] Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment.
  • Computed tomography (CT) scan demonstrated no pulmonary abnormality, but identified a retroperitoneal mass confirmed as angiomyolipoma by CT-guided core biopsy.
  • Based on experimental work that rapamycin may inhibit angiomyolipoma cells, we commenced the patient on low-dose rapamycin.
  • [MeSH-major] Angiomyolipoma / drug therapy. Antibiotics, Antineoplastic / therapeutic use. Lung Neoplasms / surgery. Lung Transplantation. Lymphangioleiomyomatosis / surgery. Neoplasms, Second Primary. Retroperitoneal Neoplasms / drug therapy. Sirolimus / therapeutic use

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  • [CommentIn] J Heart Lung Transplant. 2008 Nov;27(11):1268 [18971103.001]
  • (PMID = 18374885.001).
  • [ISSN] 1557-3117
  • [Journal-full-title] The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
  • [ISO-abbreviation] J. Heart Lung Transplant.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; W36ZG6FT64 / Sirolimus
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53. Green DE, Woodward PJ: The management of indeterminate incidental findings detected at abdominal CT. Semin Ultrasound CT MR; 2005 Feb;26(1):2-13
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  • Some of these findings can be characterized without additional imaging (including simple renal cyst, angiomyolipoma, hepatic steatosis).
  • While some of these indeterminate incidental findings can be ignored based on statistical arguments (for example, a sharply circumscribed homogeneous low-attenuation renal lesion under 1 cm in patients without a predisposition to develop renal cell carcinoma), many may need additional imaging studies to either characterize them or demonstrate stability over time.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Abdominal Neoplasms / therapy. Digestive System Diseases / diagnosis. Digestive System Diseases / therapy. Incidental Findings. Radiography, Abdominal / methods
  • [MeSH-minor] Aortic Aneurysm / diagnosis. Aortic Aneurysm / therapy. Cysts / diagnosis. Cysts / therapy. Digestive System / radiography. Humans. Tomography, X-Ray Computed / methods

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  • (PMID = 15771259.001).
  • [ISSN] 0887-2171
  • [Journal-full-title] Seminars in ultrasound, CT, and MR
  • [ISO-abbreviation] Semin. Ultrasound CT MR
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 60
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54. Zhou YM, Li B, Xu F, Wang B, Li DQ, Zhang XF, Liu P, Yang JM: Clinical features of hepatic angiomyolipoma. Hepatobiliary Pancreat Dis Int; 2008 Jun;7(3):284-7
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  • [Title] Clinical features of hepatic angiomyolipoma.
  • BACKGROUND: Hepatic angiomyolipoma (HAML) is a rare hepatic mesenchymal tumor.
  • Pre-operative diagnosis was made in only 3 patients.
  • CONCLUSIONS: Pre-operative diagnosis of HAML is difficult.
  • [MeSH-major] Angiomyolipoma / pathology. Hepatectomy / methods. Liver Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Antigens, Neoplasm / metabolism. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Melanoma-Specific Antigens. Middle Aged. Neoplasm Proteins / metabolism. Neoplasm Staging. Prognosis. Retrospective Studies

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  • (PMID = 18522883.001).
  • [ISSN] 1499-3872
  • [Journal-full-title] Hepatobiliary & pancreatic diseases international : HBPD INT
  • [ISO-abbreviation] HBPD INT
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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55. Dillon RC, Friedman AC, Miller FH: MR signal intensity calculations are not reliable for differentiating renal cell carcinoma from lipid poor angiomyolipoma. Radiology; 2010 Oct;257(1):299-300; author reply 300
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  • [Title] MR signal intensity calculations are not reliable for differentiating renal cell carcinoma from lipid poor angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged


56. Hoda MR, Popken G: Surgical outcomes of fluorescence-guided laparoscopic partial nephrectomy using 5-aminolevulinic acid-induced protoporphyrin IX. J Surg Res; 2009 Jun 15;154(2):220-5
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  • A total of 77 patients with a renal mass < 4 cm diameter underwent laparoscopic partial nephrectomy (LPN).
  • Fifty-eight of 61 (95.1%) renal cell carcinomas showed a positive response when exposed to excitation light.
  • However, characteristic fluorescence was also detected in 1 angiomyolipoma of 16 nonmalignant lesions.
  • CONCLUSIONS: PDD after systemic administration of 5-ALA is a reliable tool to assess the type and the resection status of a suspected renal tumor during laparoscopic nephron-sparing surgery.
  • [MeSH-major] Aminolevulinic Acid. Carcinoma, Renal Cell / pathology. Carcinoma, Renal Cell / surgery. Kidney Neoplasms / pathology. Kidney Neoplasms / surgery. Nephrectomy / methods. Photosensitizing Agents

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  • (PMID = 19375717.001).
  • [ISSN] 1095-8673
  • [Journal-full-title] The Journal of surgical research
  • [ISO-abbreviation] J. Surg. Res.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Protoporphyrins; 553-12-8 / protoporphyrin IX; 88755TAZ87 / Aminolevulinic Acid
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57. De Silva WA, Wijekoon NS, Quintus KD, Rajasinghe SK, Dissanayaka DM: A case of giant, isolated renal angiomyolipoma in an elderly female. Ceylon Med J; 2010 Dec;55(4):130-1
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  • [Title] A case of giant, isolated renal angiomyolipoma in an elderly female.
  • [MeSH-major] Angiomyolipoma / surgery
  • [MeSH-minor] Aged. Female. Humans. Kidney Neoplasms / radiography. Kidney Neoplasms / surgery. Tomography, X-Ray Computed

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  • (PMID = 21341630.001).
  • [ISSN] 0009-0875
  • [Journal-full-title] The Ceylon medical journal
  • [ISO-abbreviation] Ceylon Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sri Lanka
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58. Winterkorn EB, Daouk GH, Anupindi S, Thiele EA: Tuberous sclerosis complex and renal angiomyolipoma: case report and review of the literature. Pediatr Nephrol; 2006 Aug;21(8):1189-93
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  • [Title] Tuberous sclerosis complex and renal angiomyolipoma: case report and review of the literature.
  • A 5-year-old boy with a known diagnosis of tuberous sclerosis complex was found to have an enlarging renal mass on routine ultrasound.
  • He was diagnosed with an angiomyolipoma (AML) and scheduled for close observation.
  • Angiomyolipoma is a known and well-described complication of the tuberous sclerosis complex that is usually found among patients in their adolescent and adult years.
  • The case presented here illustrates the need for early and repeated renal imaging of younger pediatric patients with tuberous sclerosis.
  • Our experience adds to the literature on young pediatric patients requiring embolization for treatment of large renal angiomyolipomas.
  • [MeSH-major] Angiomyolipoma / etiology. Kidney Neoplasms / etiology. Tuberous Sclerosis / complications

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  • (PMID = 16791610.001).
  • [ISSN] 0931-041X
  • [Journal-full-title] Pediatric nephrology (Berlin, Germany)
  • [ISO-abbreviation] Pediatr. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 27
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59. Kobayashi M, Nakano K, Nukui A, Goto K, Morita T: Bilateral massive renal angiomyolipoma concurrent with oncocytoma in tuberous sclerosis complex associated with pulmonary lymphangioleiomyomatosis. Urology; 2008 Oct;72(4):948.e7-9
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  • [Title] Bilateral massive renal angiomyolipoma concurrent with oncocytoma in tuberous sclerosis complex associated with pulmonary lymphangioleiomyomatosis.
  • We describe a patient with tuberous sclerosis complex and massive bilateral renal angiomyolipomas (AMLs) in association with pulmonary lymphangioleiomatosis, who experienced hemorrhagic shock because of rupture of the left renal AML.
  • The histopathologic examination revealed concurrent oncocytomas with AMLs in the right kidney, indicating a possible shared mechanism in the pathogenesis of these two disorders.
  • This case also represents a rare, but significant, overlap between renal AML, pulmonary lymphangioleiomatosis, and tuberous sclerosis complex.
  • [MeSH-major] Adenoma, Oxyphilic / complications. Angiomyolipoma / complications. Kidney Neoplasms / complications. Lung Neoplasms / complications. Lymphangioleiomyomatosis / complications. Neoplasms, Multiple Primary / complications. Tuberous Sclerosis / complications


60. Richmond L, Atri M, Sherman C, Sharir S: Renal cell carcinoma containing macroscopic fat on CT mimics an angiomyolipoma due to bone metaplasia without macroscopic calcification. Br J Radiol; 2010 Aug;83(992):e179-81
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  • [Title] Renal cell carcinoma containing macroscopic fat on CT mimics an angiomyolipoma due to bone metaplasia without macroscopic calcification.
  • We report a case of renal cell carcinoma (RCC) containing foci of macroscopic fat, which were pathologically proven to be areas of osseous metaplasia.
  • The finding is significant because standard imaging practice is to classify a renal mass containing intratumoral macroscopic fat that is not associated with calcification, ossification or invasion of perirenal or hilar fat as an angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / radiography. Bone and Bones / pathology. Carcinoma, Renal Cell / radiography. Kidney Neoplasms / radiography. Neoplasms, Adipose Tissue / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Metaplasia / pathology. Metaplasia / radiography. Middle Aged. Tomography, X-Ray Computed / methods

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  • (PMID = 20647509.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3473503
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61. Nadu A, Laufer M, Winkler H, Kleinmann N, Ramon J: [The laparoscopic approach to renal tumors outcome of 121 laparoscopic radical and partial nephrectomy procedures]. Harefuah; 2005 Sep;144(9):609-12, 679
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  • [Title] [The laparoscopic approach to renal tumors outcome of 121 laparoscopic radical and partial nephrectomy procedures].
  • BACKGROUND AND PURPOSE: We present and review a single center experience with laparoscopic renal surgery for renal cancer including laparoscopic radical and partial nephrectomy.
  • PATIENTS AND METHODS: During the period September 2002 - January 2005, 180 patients underwent laparoscopic renal surgery at our center for several indications.
  • A total of 121 patients underwent radical nephrectomy (76) or partial nephrectomy (45) for solid renal tumors.
  • The indications for surgery were solid, enhancing renal masses.
  • The pathological examination demonstrated renal cell carcinoma in 109 cases, oncocytoma in 6 cases, angiomyolipoma in 2 cases, sarcoma of the kidney and metastasis from lung cancer in one case each and a hemorrhagic cyst in one case.
  • CONCLUSIONS: The laparoscopic approach to kidney cancer seems to be safe and oncologically sound.
  • The low morbidity rate together with the inherent advantages of laparoscopic surgery make this approach attractive and we believe it should be considered the new standard of care for renal cancer.
  • [MeSH-major] Kidney Neoplasms / surgery. Laparoscopy / methods

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  • (PMID = 16218528.001).
  • [ISSN] 0017-7768
  • [Journal-full-title] Harefuah
  • [ISO-abbreviation] Harefuah
  • [Language] heb
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Israel
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62. Fujii T, Zen Y, Sato Y, Sasaki M, Enomae M, Minato H, Masuda S, Uehara T, Katsuyama T, Nakanuma Y: Podoplanin is a useful diagnostic marker for epithelioid hemangioendothelioma of the liver. Mod Pathol; 2008 Feb;21(2):125-30
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  • In this study, we examined podoplanin expression in specimens from 10 normal livers and 73 cases of liver tumors: hemangioma (16 cases), epithelioid hemangioendothelioma (9 cases), angiosarcoma (4 cases), angiomyolipoma (7 cases), hepatocellular carcinoma (11 cases), intrahepatic cholangiocarcinoma (11 cases), and metastatic liver cancer (15 cases).
  • The expression of CD31, CD34, and factor VIII was observed in endothelial cells in all cases of hemangioma, epithelioid hemangioendothelioma, angiosarcoma, and angiomyolipoma with one exception, a case of epithelioid hemangioendothelioma which was without CD31 expression.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Angiomyolipoma / metabolism. Angiomyolipoma / pathology. Bile Duct Neoplasms / metabolism. Bile Duct Neoplasms / pathology. Bile Ducts, Intrahepatic / metabolism. Bile Ducts, Intrahepatic / pathology. Carcinoma, Hepatocellular / metabolism. Carcinoma, Hepatocellular / pathology. Cholangiocarcinoma / metabolism. Cholangiocarcinoma / pathology. Diagnosis, Differential. Endothelium, Lymphatic / metabolism. Endothelium, Lymphatic / pathology. Female. Hemangioma / metabolism. Hemangioma / pathology. Hemangiosarcoma / metabolism. Hemangiosarcoma / pathology. Humans. Liver / metabolism. Liver / pathology. Male. Middle Aged

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  • (PMID = 18084256.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Membrane Glycoproteins; 0 / PDPN protein, human
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63. Koh JL, Lee YH, Kang CY, Lin CN: Simultaneous cesarean section and radical nephrectomy for angiomyolipoma with spontaneous bleeding during pregnancy: a case report. J Reprod Med; 2007 Apr;52(4):338-40
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  • [Title] Simultaneous cesarean section and radical nephrectomy for angiomyolipoma with spontaneous bleeding during pregnancy: a case report.
  • BACKGROUND: Renal angiomyolipoma with spontaneous bleeding during pregnancy is an extremely rare condition and may jeopardize both the mother and fetus.
  • The ethics of reproductive medicine, method of diagnosis, option for management and optimal time for surgical intervention can be arguable in this situation.
  • Abdominal sonography and renal magnetic resonance imaging revealed a hypervascular and fat-containing mass with mother and fetus bleeding at the right kidney.
  • Angiomyolipoma of the right kidney was diagnosed on pathologic examination.
  • CONCLUSION: Renal angiomyolipoma with spontaneous bleeding during pregnancy is a dangerous condition that may cause mortality in the mother and fetus, but elective, simultaneous cesarean section and radical nephrectomy can be performed safely if the hemodynamic status is stable.
  • [MeSH-major] Angiomyolipoma / surgery. Cesarean Section / methods. Kidney Neoplasms / surgery. Nephrectomy / methods. Pregnancy Complications, Neoplastic / surgery


64. Dann P, Thakur R, Chin D, Krinsky G, Israel GM: Are T2-weighted images necessary in renal mass characterization? Eur J Radiol; 2006 Jul;59(1):112-6
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  • [Title] Are T2-weighted images necessary in renal mass characterization?
  • OBJECTIVE: To determine what role T2-weighted images play in characterizing renal masses.
  • METHODS: Forty-four pathologically proven renal masses (34 renal cell carcinomas, 8 oncocytomas, 1 metanephric adenoma, 1 angiomyolipoma without macroscopic fat) and 38 simple renal cysts were evaluated with T1- and T2-weighted images at 1.5T.
  • RESULTS: Forty-three of the 44 (98%) pathologically proven renal masses were characterized as a surgical mass using only the T1-weighted images.
  • The remaining renal mass (a renal cell carcinoma) was characterized as a mass in which follow-up exams would be suggested.
  • Thirty-eight of 38 (100%) simple renal cysts were correctly characterized using only the T1-weighted images.
  • CONCLUSION: The results of this study suggest that T2-weighted images are not necessary in the evaluation of all renal masses and are specifically not necessary in the differentiation of solid and cystic renal neoplasms from simple renal cysts.
  • [MeSH-major] Kidney Diseases / diagnosis. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Aged. Contrast Media. Diagnosis, Differential. Female. Gadolinium DTPA. Humans. Kidney Diseases, Cystic / diagnosis. Kidney Neoplasms / diagnosis. Male. Middle Aged

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  • (PMID = 16530371.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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65. Yen YH, Wang JH, Lu SN, Changchien CS: Contrast-enhanced ultrasonography in hepatic angiomyolipoma. J Ultrasound Med; 2005 Jun;24(6):855-9
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  • [Title] Contrast-enhanced ultrasonography in hepatic angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / ultrasonography. Liver Neoplasms / ultrasonography. Ultrasonography, Doppler / methods
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Image Enhancement. Male. Tomography, X-Ray Computed

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  • (PMID = 15914690.001).
  • [ISSN] 0278-4297
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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66. Patel U, Simpson E, Kingswood JC, Saggar-Malik AK: Tuberose sclerosis complex: analysis of growth rates aids differentiation of renal cell carcinoma from atypical or minimal-fat-containing angiomyolipoma. Clin Radiol; 2005 Jun;60(6):665-73; discussion 663-4
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  • [Title] Tuberose sclerosis complex: analysis of growth rates aids differentiation of renal cell carcinoma from atypical or minimal-fat-containing angiomyolipoma.
  • AIM: To study the radiological characteristics of renal masses in individuals with tuberous sclerosis complex (TSC) using serial CT, and to examine how renal cell carcinoma (RCC) may be differentiated from indeterminate cysts or masses.
  • METHODS: This was a retrospective study of 12 cases of TSC in which dedicated renal CT followed after US had demonstrated cystic or sonographically unusual renal masses.
  • Subjects were maintained on regular follow-up with repeat CT or MRI and interval renal US.
  • Indeterminate masses that showed rapid growth were considered suspicious for renal cell carcinoma and biopsy or nephrectomy followed.
  • In each case the renal masses were multiple and bilateral; mean mass diameter was 3.6 cm.
  • Of the complex cysts, 1 proved to be an angiomyolipoma on histology and the other 2 showed no growth.
  • CONCLUSION: Many renal masses associated with TSC are radiologically indeterminate.
  • Yearly radiological follow-up of indeterminate renal masses is recommended for individuals with TSC.
  • [MeSH-major] Angiomyolipoma / radiography. Carcinoma, Renal Cell / radiography. Kidney / radiography. Kidney Neoplasms / radiography. Tomography, X-Ray Computed. Tuberous Sclerosis / radiography
  • [MeSH-minor] Adolescent. Adult. Aged. Diagnosis, Differential. Disease Progression. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Sensitivity and Specificity


67. Radopoulos D, Tahmatzopoulos A, Kalinderis N, Dimitriadis G: Bilateral synchronous occurrence of three different histological types of renal tumor: a case report. J Med Case Rep; 2009;3:6798
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  • [Title] Bilateral synchronous occurrence of three different histological types of renal tumor: a case report.
  • INTRODUCTION: Renal cell carcinomas account for 85% of all renal neoplasms.
  • With the introduction of modern imaging modalities, there has been an increased diagnosis of renal tumors.
  • Recent studies have shown that partial nephrectomy can be as safe as radical nephrectomy for smaller renal tumors.
  • Renal cell carcinomas are usually unilateral, however, they can be bilateral in 2% to 4% of sporadic cases and considerably more common in familial cases.
  • CASE PRESENTATION: In this case report, we describe an unusual case of two bilateral synchronous chromophobe renal cell carcinomas accompanied by an oncocytoma and an angiomyolipoma, that were all treated by open partial nephrectomy.
  • CONCLUSIONS: To the best of our knowledge, this is the first case report on the synchronous occurrence of bilateral chromophobe renal cell carcinomas associated with an oncocytoma and an angiomyolipoma.

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  • (PMID = 19830124.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2726473
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68. Durgun Y, Firat C, Miman MC, Kirimlioglu H: A rare benign laryngeal tumor: angiomyolipoma. J Craniofac Surg; 2010 Nov;21(6):1956-7
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  • [Title] A rare benign laryngeal tumor: angiomyolipoma.
  • Angiomyolipoma is a mesenchymal neoplasm containing adipose tissue, blood vessels, and smooth muscle fibers.
  • Arising most frequently in the kidney, the tumor may exceptionally be at the head and neck region.
  • The literature has 1 single published report of laryngeal angiomyolipoma, which was resected through laryngofissure.
  • In this study, a 58-year-old man presented with laryngeal angiomyolipoma with swallowing discomfort.
  • [MeSH-major] Angiomyolipoma / diagnosis. Laryngeal Neoplasms / diagnosis
  • [MeSH-minor] Deglutition Disorders / diagnosis. Follow-Up Studies. Humans. Laryngoscopy. Male. Microsurgery. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 21119467.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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69. Koo KC, Kim WT, Ham WS, Lee JS, Ju HJ, Choi YD: Trends of presentation and clinical outcome of treated renal angiomyolipoma. Yonsei Med J; 2010 Sep;51(5):728-34
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  • [Title] Trends of presentation and clinical outcome of treated renal angiomyolipoma.
  • PURPOSE: The purpose of this study is to set guidelines for the management of renal angiomyolipoma (AML), clinical prognosis according to tumor size, in association with tuberous sclerosis complex (TSC), multiplicity, radiographic finding, and treatment modality.
  • Diagnosis of AML was determined by the presence of a low attenuated component on CT imaging or by pathological confirmation.
  • Indications of treatment were intractable pain, hematuria, suspicion of malignancy, large tumor size, spontaneous rupture, and radiographically equivocal tumors in which a differential diagnosis was needed to rule out malignancy.
  • No patient developed renal function impairment during the mean follow-up period of 64.8 months.
  • [MeSH-major] Angiomyolipoma / pathology. Angiomyolipoma / surgery. Kidney Neoplasms / pathology. Kidney Neoplasms / surgery

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  • (PMID = 20635448.001).
  • [ISSN] 1976-2437
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2908871
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70. Yamagata Y, Kawauchi S, Tamura H, Murakami A, Sasaki K, Sugino N: A case of HMB45-negative perivascular epithelioid cell tumor (PEComa) of the uterine corpus: a possible diagnostic application of molecular-cytogenetic analysis. Eur J Gynaecol Oncol; 2009;30(2):216-9
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  • We report a case of uterine angiomyolipoma confirmed with molecular-genetic analysis by fluorescence in situ hybridization (FISH).
  • FISH examination revealed chromosome X trisomy, which was comparable to a previously reported molecular-genetic finding of PEComa family tumors including angiomyolipoma.
  • Although the tumor was immunohistochemically negative for HMB-45 antigen, the histological and FISH findings were compatible with angiomyolipoma.
  • [MeSH-major] Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Neoplasm Proteins / analysis. Perivascular Epithelioid Cell Neoplasms / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Adult. Angiomyolipoma / diagnosis. Angiomyolipoma / immunology. Angiomyolipoma / pathology. Chromosomes, Human, X / genetics. Cytogenetic Analysis. Female. Humans. In Situ Hybridization, Fluorescence. Melanoma-Specific Antigens. Trisomy

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  • (PMID = 19480261.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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71. Yang Y, Song Y, Hong BF: [The use of balloon catheter in surgical treatment of renal angiomyolipoma with a caval thrombus: 1 case report and literature review]. Zhonghua Wai Ke Za Zhi; 2007 Jun 15;45(12):836-8
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  • [Title] [The use of balloon catheter in surgical treatment of renal angiomyolipoma with a caval thrombus: 1 case report and literature review].
  • OBJECTIVE: To present one cases of the use of balloon catheter in surgical treatment of renal angiomyolipoma involving the renal vein and vena cava as a tumor thrombus and review literatures.
  • METHODS: Abdominal ultrasound and CT and MRI demonstrated a large right renal mass with tumor thrombus in the inferior vena cava.
  • RESULTS: The pathological diagnosis was angiomyolipoma.
  • CONCLUSION: Renal angiomyolipoma with a tumor thrombus should be paid more attention.
  • [MeSH-major] Angiomyolipoma / surgery. Balloon Occlusion. Embolectomy / methods. Embolism / surgery. Kidney Neoplasms / surgery

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  • (PMID = 17845787.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 10
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72. Minervini A, Giubilei G, Masieri L, Lanzi F, Serni S, Carini M: Simple enucleation for the treatment of renal angiomyolipoma. BJU Int; 2007 Apr;99(4):887-91
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  • [Title] Simple enucleation for the treatment of renal angiomyolipoma.
  • OBJECTIVES: To report on the role of simple enucleation for treating renal angiomyolipoma (AML) in a series of patients treated in our department.
  • PATIENTS AND METHODS: We retrospectively reviewed the data of all 37 patients with a histopathological diagnosis of renal AML who had either radical nephrectomy (three) or nephron-sparing surgery by simple enucleation (34) between January 1986 and December 2005.
  • Indications for intervention included either symptomatic AML or a tumour of >4 cm, regardless to the presence of symptoms or renal masses suspicious of malignancy.
  • Two patients (6%) required renal hypothermia.
  • There were no major complications, e.g. prolonged acute tubular necrosis/chronic renal insufficiency and urinary leakage/urinoma, but two patients had urosepsis not associated with perirenal fluid collection and that required targeted antibiotic therapy.
  • Two patients had a small AML elsewhere in the operated kidney, detected 18 and 36 months after surgery, with a kidney recurrence rate of 6%.
  • CONCLUSIONS: Our data confirm the optimum results of simple enucleation for renal AMLs; this technique provides excellent long-term local control and no patient had urinary leakage/fistula afterward.
  • [MeSH-major] Angiomyolipoma / surgery. Kidney Neoplasms / surgery. Nephrectomy / methods

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  • (PMID = 17233805.001).
  • [ISSN] 1464-4096
  • [Journal-full-title] BJU international
  • [ISO-abbreviation] BJU Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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73. Lenton J, Kessel D, Watkinson AF: Embolization of renal angiomyolipoma: immediate complications and long-term outcomes. Clin Radiol; 2008 Aug;63(8):864-70
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  • [Title] Embolization of renal angiomyolipoma: immediate complications and long-term outcomes.
  • AIMS: To report the outcomes of elective and emergency embolization of renal angiomyolipoma and describe an angiographic sign that will help localize the symptomatic aneurysm in emergency cases.
  • MATERIALS AND METHODS: A retrospective review of all patients undergoing embolization of renal angiomyolipoma at a two centres between 1998-2007.
  • Thirteen were elective procedures for large or symptomatic angiomyolipoma and 10 were acute procedures for patients presenting with retroperitoneal haemorrhage.
  • Patients presenting acutely with haemorrhage tended to have extensive multifocal renal involvement.
  • CONCLUSIONS: Embolization of renal angiomyolipoma produces durable results.
  • The presence of the light bulb sign is a strong indicator of the site of haemorrhage within the kidney.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy

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  • (PMID = 18625350.001).
  • [ISSN] 1365-229X
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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74. Berger J, Valgueblasse E, Thereaux J, Plainard X, Bouhlel A, Lanoe M, Paraf F, Cornu F, Dumas JP, Flam T, Zerbib M, Debre B, Descazeaud A: [Preoperative factors of misdiagnosis of renal angiomyolipoma]. Prog Urol; 2009 May;19(5):301-6
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  • [Title] [Preoperative factors of misdiagnosis of renal angiomyolipoma].
  • OBJECTIVES: To explain the high incidence of misdiagnosis of angiomyolipoma (AML) prior to surgery.
  • MATERIALS AND METHODS: Between 1989 and 2007, 2,657 patients were operated for a renal tumor at Dupuytren hospital in Limoges and at Cochin hospital in Paris.
  • The group of patients in which the diagnosis was done preoperatively was compared to the one in which the diagnosis was missed.
  • The diagnosis of AML was ignored preoperatively in 62 patients (73%).
  • The diagnosis seems particularly difficult when the tumor is small or contains a small proportion of fat.
  • In addition, this study highlights that the diagnosis of AML is frequently ignored in men.
  • [MeSH-major] Angiomyolipoma / diagnosis. Diagnostic Errors. Kidney Neoplasms / diagnosis

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  • (PMID = 19393534.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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75. Glasgow CG, Steagall WK, Taveira-Dasilva A, Pacheco-Rodriguez G, Cai X, El-Chemaly S, Moses M, Darling T, Moss J: Lymphangioleiomyomatosis (LAM): molecular insights lead to targeted therapies. Respir Med; 2010 Jul;104 Suppl 1:S45-58
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  • LAM is a rare lung disease, found primarily in women of childbearing age, characterized by cystic lung destruction and abdominal tumors (e.g., renal angiomyolipoma, lymphangioleiomyoma).

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  • [Copyright] Copyright (c) 2010. Published by Elsevier Ltd.
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  • (PMID = 20630348.001).
  • [ISSN] 1532-3064
  • [Journal-full-title] Respiratory medicine
  • [ISO-abbreviation] Respir Med
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 HL002541-12; United States / Intramural NIH HHS / / Z01 HL002541-13; United States / Intramural NIH HHS / / ZIA HL002541-14
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p21; 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein; EC 2.7.1.1 / TOR Serine-Threonine Kinases
  • [Other-IDs] NLM/ NIHMS206406; NLM/ PMC3030250
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76. Zisman A, Patard JJ, Raz O, Klatte T, Haifler M, Mendlovic S, Sandbank J, Belldegrun AS, Lindner A, Leibovici D, Pantuck AJ: Sex, age, and surgeon decision on nephron-sparing surgery are independent predictors of renal masses with benign histologic findings--a multicenter survey. Urology; 2010 Sep;76(3):541-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sex, age, and surgeon decision on nephron-sparing surgery are independent predictors of renal masses with benign histologic findings--a multicenter survey.
  • OBJECTIVES: To define the preoperative independent predictors indicating that renal mass has benign histologic features.
  • METHODS: A total of 1664 patients with Stage T1-T2N0M0 with a unilateral renal mass underwent nephrectomy.
  • High-grade renal cell carcinoma was more prevalent in men (31% versus 21%, P = .001).
  • The histologic tumor types were distributed differently between the 2 sexes: 8% papillary renal cell carcinoma in women versus 16% in men, 86% and 78% clear cell renal cell carcinoma, 33% and 57% oncocytoma, and 40% versus 12% angiomyolipoma, respectively.
  • CONCLUSIONS: Renal tumors were consistently benign in 20% of women, regardless of size.
  • [MeSH-major] Kidney Neoplasms / pathology. Kidney Neoplasms / surgery. Nephrectomy

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • [CommentIn] Urology. 2010 Sep;76(3):546-7; discussion 547 [20832600.001]
  • (PMID = 20494411.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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77. Schirmang TC, Mayo-Smith WW, Dupuy DE, Beland MD, Grand DJ: Kidney neoplasms: renal halo sign after percutaneous radiofrequency ablation--incidence and clinical importance in 101 consecutive patients. Radiology; 2009 Oct;253(1):263-9
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  • [Title] Kidney neoplasms: renal halo sign after percutaneous radiofrequency ablation--incidence and clinical importance in 101 consecutive patients.
  • PURPOSE: To describe the incidence and clinical importance of the renal halo sign after percutaneous radiofrequency ablation (RFA) of renal neoplasms.
  • The study population consisted of 101 consecutive patients with 106 solid renal neoplasms that were treated with percutaneous RFA.
  • Postablation computed tomographic (CT) and magnetic resonance (MR) images were retrospectively reviewed by three board-certified radiologists to determine the presence of the renal halo sign.
  • Statistical analyses were performed to determine reader agreement and assess the effect that tumor size and location, radiofrequency (RF) applicator type, RFA treatment time and success, maximum RFA treatment temperature, and number of RF applications performed had on development of the renal halo sign.
  • RESULTS: The renal halo sign developed in 79 (75%) of the 106 ablated tumors.
  • The renal halo sign appeared, on average, 6 months (range, 1 month to 3 years) after RFA.
  • The renal halo sign resolved in five (6%) of 79 tumors treated.
  • Interobserver agreement for the presence of the renal halo sign was high.
  • Tumor size and location, RF applicator type, RFA treatment time and success, maximum RFA treatment temperature, and number of RF applications performed were not independent predictors of renal halo sign development.
  • CONCLUSION: The renal halo sign is seen in 75% of patients after percutaneous RFA of renal neoplasms.
  • It is important to recognize this sign, as it can be mistaken for recurrent tumor or angiomyolipoma by radiologists who are not familiar with RFA.
  • [MeSH-major] Catheter Ablation. Kidney Neoplasms / pathology. Kidney Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Angiomyolipoma / diagnosis. Contrast Media. Diagnosis, Differential. Female. Humans. Incidence. Kidney / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Retrospective Studies. Tomography, Spiral Computed

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  • (PMID = 19703853.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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78. Farrelly C, Delaney H, McDermott R, Malone D: Do all non-calcified echogenic renal lesions found on ultrasound need further evaluation with CT? Abdom Imaging; 2008 Jan-Feb;33(1):44-7
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  • [Title] Do all non-calcified echogenic renal lesions found on ultrasound need further evaluation with CT?
  • BACKGROUND: This is a study using Evidence Based Practice (EBP) technique to evaluate if non-calcified renal lesions detected with ultrasound, suspected to represent an angiomyolipoma (AML), need a CT to rule out a renal cell carcinoma (RCC).
  • Overall, hyperechoic non-calcified renal lesions had a sensitivity of 0.99 (95% confidence interval (CI) 0.97-1.00), a specificity of 0.43 (95% CI 0.34-0.51), a positive predictive value (PPV) of 0.58 and a negative predictive value (NPV) of 0.98 for AMLs.
  • 57.4% of RCCs were hyperechoic to renal parenchyma.
  • CONCLUSIONS: From the surprisingly limited evidence available in the literature, it must be concluded that all non-calcified echogenic renal lesions detected with ultrasound need a CT to rule out an RCC.
  • [MeSH-major] Angiomyolipoma / ultrasonography. Kidney Neoplasms / ultrasonography
  • [MeSH-minor] Carcinoma, Renal Cell / radiography. Carcinoma, Renal Cell / ultrasonography. Diagnosis, Differential. Evidence-Based Medicine. Humans. Incidental Findings. Sensitivity and Specificity. Tomography, X-Ray Computed

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  • (PMID = 17849156.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 8
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79. Cindolo L, Berardinelli F, Gidaro S, Schips L: Laparoendoscopic single-site partial nephrectomy without ischemia. J Endourol; 2010 Dec;24(12):1997-2002
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  • BACKGROUND AND PURPOSE: Nephron-sparing surgery (NSS) ensures excellent oncologic and functional outcomes in small renal masses.
  • PATIENTS AND METHODS: From April to September 2009, all consecutive patients with solitary, exophytic, enhancing, small (≤4.0 cm) renal masses and normal contralateral kidney were selected to receive LESS unclamp-NSS.
  • Rigid and articulable instruments were used for dissection, tumor exposure, and excision under normal renal perfusion.
  • RESULTS: Six patients underwent LESS unclamp-NSS (mean operative time, 148 min; mean blood loss, 201 mL; mean renal masses size, 2.1cm).
  • Pathologic examination revealed two clear-cell carcinoma, three benign cysts, and one angiomyolipoma (surgical margin positive).
  • CONCLUSION: LESS unclamp-NSS in selected renal masses is feasible, provides postoperative outcomes overlapping the standard counterpart, and ensures subjective satisfaction.

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  • (PMID = 20964485.001).
  • [ISSN] 1557-900X
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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80. El-Esawy SS, Abou El-Ghar ME, Gaballa GM, Zahra SA: Characterization of solid renal masses using 64-slice multidetector CT scanner. ScientificWorldJournal; 2009;9:441-8
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  • [Title] Characterization of solid renal masses using 64-slice multidetector CT scanner.
  • The purpose of our study was to assess the role of a 64-slice multidetector CT (MDCT) scanner in the characterization of different solid renal masses, using a simplified approach to correct the postenhancement attenuation values.
  • The study included 96 consecutive adults (58 men, 38 women) with renal masses; 93 with unilateral and three with bilateral masses.
  • There were 53 masses at the right kidney, 40 at the left kidney, and three bilateral.
  • The final diagnosis of the 96 solid parenchymal masses were 28 clear-type renal cell carcinoma (RCC), 22 papillary-type RCC, 21 chromophobe-type RCC, six XP 11.2 chromosomal translocation-type RCC, 15 angiomyolipoma (AML), and seven oncocytoma.
  • The 64-slice MDCT scanner with application of enhancement values correction allows diagnosis of clear cell carcinoma.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Kidney / radiography. Kidney Neoplasms / diagnosis. Tomography, X-Ray Computed / methods

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  • (PMID = 19526183.001).
  • [ISSN] 1537-744X
  • [Journal-full-title] TheScientificWorldJournal
  • [ISO-abbreviation] ScientificWorldJournal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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81. Suh KS, Kim TG, Jeon YS, Kim ST: The revision of the article entitled "a case of a cutaneous angiomyolipoma". Ann Dermatol; 2009 Aug;21(3):334
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  • [Title] The revision of the article entitled "a case of a cutaneous angiomyolipoma".

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  • (PMID = 20523819.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2861236
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82. Hu JZ, Li YL, He J, Liu HM, Yu HY: [Concurrent angiomyolipoma and clear cell renal cell carcinoma: report of a case]. Zhonghua Bing Li Xue Za Zhi; 2006 Aug;35(8):512
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Concurrent angiomyolipoma and clear cell renal cell carcinoma: report of a case].
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Angiomyolipoma / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology


83. Theodosopoulos T, Yiallourou A, Kyriazi M, Anastasopoulos G, Kairi-Vassilatou E, Dafnios N, Vassiliou I: Unilateral simultaneous renal oncocytoma and angiomyolipoma: case report. Cases J; 2009;2:9093
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  • [Title] Unilateral simultaneous renal oncocytoma and angiomyolipoma: case report.
  • A rare case of synchronous angiomyolipoma and oncocytoma in the same kidney of a 70 year old man is presented.
  • A left renal mass was found incidentally by ultrasound.
  • Computerized tomography and magnetic resonance imaging revealed a 1,3 cm mass in the mid-portion of the left kidney, whereas on the lower pole of the same kidney, a 3,3 cm mass was also revealed, consistent with angiomyolipoma.
  • A working diagnosis of renal cell carcinoma was made.
  • Microscopically, the tumor of the lower pole was found to be an angiomyolipoma, whereas the mid-portion tumor was an oncocytoma.
  • Until now, only 16 cases of unilateral simultaneous presence of renal angiomyolipoma and oncocytoma have been reported.
  • It is well worth remarking, that renal oncocytoma overlap with other renal neoplasms, therefore nephrectomy remains the treatment of choice.Renal angiomyolipoma and oncocytoma are uncommon neoplasms and their simultaneous presence in the same kidney is rare.

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  • (PMID = 20062730.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2803890
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84. Del Sordo R, Colella R, Leite S, Sidoni A: [Cutaneous angiomyolipoma: a case report and literature review]. Pathologica; 2005 Jun;97(3):137-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cutaneous angiomyolipoma: a case report and literature review].
  • [Transliterated title] Angiomiolipoma cutaneo: descrizione di un caso e revisione della letteratura.
  • Angiomyolipoma is a lesion usually observed in the kidney of patients with tuberous sclerosis.
  • [MeSH-major] Angiomyolipoma / pathology. Ear Neoplasms / pathology. Ear, External / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Male. Middle Aged. Neoplasm Proteins / analysis

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  • (PMID = 16259281.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
  • [Number-of-references] 10
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85. Sooriakumaran P, Gibbs P, Coughlin G, Attard V, Elmslie F, Kingswood C, Taylor J, Corbishley C, Patel U, Anderson C: Angiomyolipomata: challenges, solutions, and future prospects based on over 100 cases treated. BJU Int; 2010 Jan;105(1):101-6
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  • OBJECTIVE: To examine the presentation, management and outcomes of patients with renal angiomyolipoma (AML) over a period of 10 years, at St George's Hospital, London, UK.
  • [MeSH-major] Angiomyolipoma / therapy. Catheter Ablation / methods. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy. Nephrectomy / methods. Tuberous Sclerosis / therapy


86. Boorjian SA, Frank I, Inman B, Lohse CM, Cheville JC, Leibovich BC, Blute ML: The role of partial nephrectomy for the management of sporadic renal angiomyolipoma. Urology; 2007 Dec;70(6):1064-8
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  • [Title] The role of partial nephrectomy for the management of sporadic renal angiomyolipoma.
  • OBJECTIVES: Angiomyolipoma is a benign renal tumor that has a propensity to grow over time and may cause local complications.
  • Given the benign nature of these lesions, renal-preserving treatments are favored.
  • We evaluated our experience with nephron-sparing surgery for renal angiomyolipoma.
  • METHODS: We reviewed our institutional nephrectomy registry to identify patients treated with nephron-sparing surgery for renal angiomyolipoma between 1970 and 2004.
  • Patients with a diagnosis of tuberous sclerosis were excluded.
  • RESULTS: We identified 58 patients treated with nephron-sparing surgery for sporadic renal angiomyolipoma, including 44 women and 14 men.
  • No patient developed de novo chronic renal insufficiency after nephron-sparing surgery, including 4 patients treated for angiomyolipomas in a solitary kidney.
  • CONCLUSIONS: Nephron-sparing surgery for sporadic renal angiomyolipomas offers preservation of renal function and is associated with acceptable complication and low local recurrence rates.
  • [MeSH-major] Angiomyolipoma / surgery. Kidney Neoplasms / surgery. Nephrectomy

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  • (PMID = 18158015.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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87. Wienecke R, Fackler I, Linsenmaier U, Mayer K, Licht T, Kretzler M: Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex. Am J Kidney Dis; 2006 Sep;48(3):e27-9
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  • [Title] Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex.
  • A 19-year old patient with tuberous sclerosis presented with a renal angiomyolipoma.
  • Because animal trials of tuberous sclerosis showed an effect of rapamycin on renal tumors, our patient was administered rapamycin for 6 months.
  • During this time, the renal angiomyolipoma shrank significantly, regrew during an 8-month period, and decreased in size again after readministration of rapamycin.
  • [MeSH-major] Angiomyolipoma / drug therapy. Antibiotics, Antineoplastic / therapeutic use. Kidney Neoplasms / drug therapy. Sirolimus / therapeutic use. Tuberous Sclerosis / complications

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  • (PMID = 16931204.001).
  • [ISSN] 1523-6838
  • [Journal-full-title] American journal of kidney diseases : the official journal of the National Kidney Foundation
  • [ISO-abbreviation] Am. J. Kidney Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; W36ZG6FT64 / Sirolimus
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88. Kozłowska J, Okoń K: Renal tumors in postmortem material. Pol J Pathol; 2008;59(1):21-5
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  • [Title] Renal tumors in postmortem material.
  • Renal tumors include several categories, the most frequent being clear cell renal cell carcinoma, papillary renal cell carcinoma, chromophobe carcinoma, oncocytoma, adenoma and angiomyolipoma.
  • The aim of the study was to analyze the incidence of renal tumors in autopsy material.
  • Among 3512 autopsies performed in our institution in the last decade, we found 97 post mortem examinations in which 108 renal tumors were detected.
  • The most frequent diagnosis was adenoma (53 cases, 49.1%) and, among cancers, clear cell carcinoma (20 cases, 21.1%) followed by papillary carcinoma (17 cases, 15.5%).
  • Less frequent lesions were angiomyolipoma (4 cases), oncocytoma (4 cases), unclassified renal cell carcinoma (3 cases), medullary fibroma (5 cases) leiomyoma (1 case) and urothelial carcinoma (1 case).
  • The adenomas were significantly more frequent in cases of kidneys with chronic fibrosis.
  • When comparing the present series to surgical material from a similar period, of note is that 44% of renal carcinomas in the autopsy series were papillary, but only 9.4% were papillary in the surgical material.
  • [MeSH-major] Kidney Neoplasms / pathology
  • [MeSH-minor] Adenoma / epidemiology. Adenoma / pathology. Adenoma / surgery. Adult. Aged. Aged, 80 and over. Carcinoma, Papillary / epidemiology. Carcinoma, Papillary / pathology. Carcinoma, Papillary / surgery. Carcinoma, Renal Cell / epidemiology. Carcinoma, Renal Cell / pathology. Carcinoma, Renal Cell / surgery. Female. Humans. Male. Middle Aged. Poland / epidemiology

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  • (PMID = 18655367.001).
  • [ISSN] 1233-9687
  • [Journal-full-title] Polish journal of pathology : official journal of the Polish Society of Pathologists
  • [ISO-abbreviation] Pol J Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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89. Zheng RQ, Kudo M, Ishikawa E, Chung H, Minami Y, Ogawa C, Sakaguchi Y, Kitano M, Kawasaki T, Maekawa K: Hepatic angiomyolipoma: identification of an efferent vessel as a hepatic vein by contrast-enhanced harmonic sonography. J Med Ultrason (2001); 2005 Dec;32(4):191-6
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  • [Title] Hepatic angiomyolipoma: identification of an efferent vessel as a hepatic vein by contrast-enhanced harmonic sonography.
  • Two cases of hepatic angiomyolipoma were studied by contrast-enhanced harmonic sonography.
  • The special tumor hemodynamics, namely the efferent blood flow of the hepatic angiomyolipoma draining into the hepatic vein, were clearly shown on harmonic imaging, and they corresponded well with those seen on angiography and computed tomography during angiography.
  • Hepatic angiomyolipoma was finally identified histologically.
  • The special tumor hemodynamics might be one of the important characteristics of hepatic angiomyolipoma.
  • Contrast-enhanced harmonic sonography is useful for the detection of special tumor hemodynamics and may facilitate the differential diagnosis from other hepatic tumors, especially malignant liver tumors.

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  • (PMID = 27277488.001).
  • [ISSN] 1346-4523
  • [Journal-full-title] Journal of medical ultrasonics (2001)
  • [ISO-abbreviation] J Med Ultrason (2001)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; contrast-enhanced sonography / hepatic angiomyolipoma / ultrasound
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90. Lane BR, Aydin H, Danforth TL, Zhou M, Remer EM, Novick AC, Campbell SC: Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid. J Urol; 2008 Sep;180(3):836-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid.
  • Histologically confirmed angiomyolipomas uniformly follow a benign course but rare epithelioid variants of angiomyolipoma can recur and metastasize.
  • We investigated the clinical, radiographic and histological characteristics of each angiomyolipoma subtype.
  • MATERIALS AND METHODS: Pertinent data were recorded for 209 patients surgically treated for angiomyolipoma in 219 kidneys from 1981 to 2007.
  • RESULTS: Median radiographic size was 3.2, 4.9 and 10 cm in patients with a single angiomyolipoma (59% of patients), multiple angiomyolipomas and tuberous sclerosis (probable or definite), respectively.
  • In these 3 groups 65%, 47% and 33% of lesions were not suspected radiographically (fat poor angiomyolipoma).
  • Despite potentially aggressive findings in 18% (eg presence within the perinephric fat, lymph node involvement) no angiomyolipoma recurred during a mean followup of 3.4 years (range 0 to 24).
  • A total of 28 (13%) patients with angiomyolipoma had concomitant renal cell carcinoma.
  • CONCLUSIONS: A surprisingly high number of resected angiomyolipomas was not suspected radiographically indicating the importance of precise radiographic characterization to minimize nephrectomy for fat poor angiomyolipoma, which should remain a research priority.
  • In this sizeable single institution series no triphasic, monophasic or epithelioid angiomyolipoma recurred despite potentially aggressive findings in a substantial proportion of cases.
  • [MeSH-major] Angiomyolipoma / classification. Kidney Neoplasms / classification
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Renal Cell / complications. Contrast Media. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Nephrectomy. Retrospective Studies. Risk Factors. Tomography, X-Ray Computed. Treatment Outcome. Tuberous Sclerosis / complications

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  • (PMID = 18635231.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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91. Seveso M, Maugeri O, Taverna G, Giusti G, Piccinelli A, Benetti A, Pasini L, Graziotti P: Incidence and treatment of complications in nephron sparing surgery. Arch Ital Urol Androl; 2005 Dec;77(4):206-10
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  • Conservative renal surgery (enucleation or segmentary resection) has become the gold standard treatment for small and peripheral malignant kidney lesions or in cases of reduced renal function or bilateral lesions.
  • MATERIALS AND METHODS: Between March 1997 and March 2005, 159 patients aged from 23 to 77 years (median 66 years) underwent conservative renal surgery.
  • In 92 patients lesions were located in the upper pole, 41 in the lower pole and 24 were meso-renal .
  • Major complications were: two massive hemorrhage, two arteriovenous fistula, one lesion of the ureter, five cases of acute kidney failure.
  • The five acute kidney failures involved patients with functional or anatomical solitary kidney.
  • Ureter lesion characterised the post-operative course of one solitary kidney patient affected by voluminous angiomyolipoma.
  • No other major complications were noted, with the exception of delay in intestinal canalization occurring in a 74 year old patient, and a wound infection in a patient with previous renal abscess associated to infundibular lithiasis and caliceal exclusion.
  • CONCLUSIONS: Conservative renal surgery is a valid alternative to radical surgery.
  • Therefore, nephron sparing surgery (NSS) can be performed with safety and maximum preservation of renal function.

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  • (PMID = 16444934.001).
  • [ISSN] 1124-3562
  • [Journal-full-title] Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
  • [ISO-abbreviation] Arch Ital Urol Androl
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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92. Nepple KG, Bockholt NA, Dahmoush L, Williams RD: Giant renal angiomyolipoma without fat density on CT scan: case report and review of the literature. ScientificWorldJournal; 2010;10:1334-8
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  • [Title] Giant renal angiomyolipoma without fat density on CT scan: case report and review of the literature.
  • Giant renal angiomyolipomas have been reported, but typically have the pathognomonic finding of fat density on CT scan.
  • We present the case of a 53-year-old male with a symptomatic, 35-cm, predominantly cystic renal mass without fat density on CT that on nephrectomy was found to be a fat-poor angiomyolipoma with predominantly epithelioid morphology weighing 17.9 kg.
  • Giant renal angiomyolipoma without macroscopic fat density on CT scan is an exceedingly rare occurrence.
  • [MeSH-major] Angiomyolipoma / radiography. Kidney Neoplasms / radiography

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  • (PMID = 20623093.001).
  • [ISSN] 1537-744X
  • [Journal-full-title] TheScientificWorldJournal
  • [ISO-abbreviation] ScientificWorldJournal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 24
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93. Rimon U, Duvdevani M, Garniek A, Golan G, Bensaid P, Ramon J, Morag B: Ethanol and polyvinyl alcohol mixture for transcatheter embolization of renal angiomyolipoma. AJR Am J Roentgenol; 2006 Sep;187(3):762-8
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  • [Title] Ethanol and polyvinyl alcohol mixture for transcatheter embolization of renal angiomyolipoma.
  • OBJECTIVE: The purpose of this study was to assess the immediate and midterm effects of embolization of the angiogenic component of renal angiomyolipoma in which a mixture of ethanol and polyvinyl alcohol is used as a permanent obliterator.
  • MATERIALS AND METHODS: Seventeen patients with 18 renal angiomyolipomas (size range, 5.5-20 cm; mean size, 10 cm) were treated with transcatheter embolization over an 8-year period.
  • CONCLUSION: We found a mixture of ethanol and polyvinyl alcohol an efficient embolizing agent with a sustained midterm effect in the management of renal angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / therapy. Embolization, Therapeutic / methods. Kidney Neoplasms / therapy

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  • (PMID = 16928942.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Sclerosing Solutions; 3K9958V90M / Ethanol; 9002-89-5 / Polyvinyl Alcohol
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94. Han XN, Peng LR, Liu GH, Wang J: [Multiphasic spiral CT scanning features in 100 patients with small renal cell carcinoma]. Zhonghua Zhong Liu Za Zhi; 2007 May;29(5):382-5
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  • [Title] [Multiphasic spiral CT scanning features in 100 patients with small renal cell carcinoma].
  • OBJECTIVE: To investigate the role of multiphasic spiral computed tomography (SCT) in the differential diagnosis of small renal cell carcinoma.
  • METHODS: The data of 100 patients with small renal cell carcinoma (< or = 3.0 cm) proved by pathology were retrospectively reviewed in order to analyze the features of SCT during plain, corticomedullary and excretory phases.
  • RESULTS: There were 38 tumor masses in the left kidney and 62 in the right one.
  • According to the 2004 WHO histological classification criteria for the tumors of the kidney.
  • Seventy-six patients had clear cell renal cell carcinoma, 4 multilocular clear cell renal cell carcinomas, 9 papillary renal cell carcinoma, 4 chromophobe renal cell carcinomas and 7 unclassified renal cell carcinomas.
  • Clear cell renal cell carcinoma exhibited rich blood supply and inhomogeneous density due to hemorrhage, necrosis or cystic degeneration.
  • Multilocular clear cell renal cell carcinoma presented as a multilocular cystic mass with thin wall and septa, instead of an expansile nodule.
  • Papillary renal cell carcinoma showed inhomogeneous density and hypovascular distribution.
  • Chromophobe renal cell carcinoma was relatively homogeneous and hypovascular.
  • Compared with clear cell renal cell carcinoma, unclassified renal cell carcinoma showed inhomogeneous density and hypervascular distribution with more invading growth features than the other subtypes.
  • CONCLUSION: Commonly encountered subtypes of the small renal cell carcinoma exhibit their own specific features in multiphasic spiral CT, which may be helpful in differential diagnosis, but each subtype should be differentiated from the renal oncocytoma, cystic nephroma, complex renal cyst, renal angiomyolipoma with minimal fat and renal infiltrating urothelial carcinoma.
  • [MeSH-major] Carcinoma, Renal Cell / radiography. Kidney Neoplasms / radiography. Tomography, Spiral Computed / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Papillary / radiography. Child. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Prognosis. Retrospective Studies

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  • (PMID = 17892138.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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95. Sun H, Xue HD, Liu W, Wang Y, Zhao WM, Jin ZY: [Perfusion characteristics of renal mass with 64-slice spiral computed tomography]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2008 Dec;30(6):680-5
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  • [Title] [Perfusion characteristics of renal mass with 64-slice spiral computed tomography].
  • OBJECTIVE: To investigate the perfusion characteristics of renal mass parenchyma on 64-slice spiral computed tomography (CT).
  • METHODS: Totally 91 patients with renal mass were enrolled.
  • Sixty-four slice spiral CT was used for renal perfusion scan that began with a contrast bolus injection of 50 ml (370 mgI/ml) at a rate of 5 ml/s.
  • Perfusion characteristics, including blood flow (BF), blood volume (BV), and permeability (PM) of renal mass parenchyma and renal cortex in affected and normal kidneys were calculated from Siemens Body PCT (VB20B) software, and the perfusion characteristics among renal mass parenchyma and renal cortex in affected and normal kidneys were compared.
  • RESULTS: Renal clear cell carcinoma (RC-CC), renal pelvic transitional cell carcinoma (RPTCC), and renal angiomyolipoma (RAML) was pathologically confirmed in 40, 21, and 16 patients, respectively, while the remaining 14 patients were diagnosed as with renal simple cyst (RSC).
  • 1) between mass parenchyma and renal cortex in affected kidney, while there were no significant differences (P > 0.
  • 5) in perfusion characteristics between renal cortex in affected and normal kidneys.
  • Aslo, the perfusion characteristics were significantly different between parenchyma D in any two kinds of renal masses (P <0 .
  • C ONCLUSIONS: fDif-rent pathological types of renal mass have different perfusion characteristics.
  • Perfusion imaging with multislice CT is potentially useful in the differential diagnosis of renal mass.
  • [MeSH-major] Kidney Neoplasms / diagnosis. Kidney Neoplasms / radionuclide imaging

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  • (PMID = 19180916.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] Clinical Trial; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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96. Urban T: [Pulmonary lymphangioleiomyomatosis with or without tuberous sclerosis]. Rev Mal Respir; 2007 Jun;24(6):725-40
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  • BACKGROUND: Other lesions such as chylothorax or renal angiomyolipoma may suggest the diagnosis.
  • [MeSH-major] Lung Neoplasms / diagnosis. Lymphangioleiomyomatosis / diagnosis. Tuberous Sclerosis / complications

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  • (PMID = 17632432.001).
  • [ISSN] 0761-8425
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein
  • [Number-of-references] 147
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97. Coumbaras M, Dahan H, Strauss C, Bouzar N, Lenoir S, Vallancien G, Palau R: [Renal angiomyolipoma complicated by extension to the renal vein and inferior vena cava]. J Radiol; 2006 May;87(5):572-4
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  • [Title] [Renal angiomyolipoma complicated by extension to the renal vein and inferior vena cava].
  • Renal angiomyolipomas are renal hamartomas.
  • We report a case of angiomyolipoma with sonographic and CT evidence of extension to the renal vein and inferior vena cava.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Renal Veins. Vascular Neoplasms / diagnosis. Vena Cava, Inferior

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  • (PMID = 16733416.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 12
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98. Lee PS, Tsang SW, Moses MA, Trayes-Gibson Z, Hsiao LL, Jensen R, Squillace R, Kwiatkowski DJ: Rapamycin-insensitive up-regulation of MMP2 and other genes in tuberous sclerosis complex 2-deficient lymphangioleiomyomatosis-like cells. Am J Respir Cell Mol Biol; 2010 Feb;42(2):227-34
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  • We studied immortalized cells that lack TSC2 derived from an angiomyolipoma of a patient with LAM, a TSC2 addback derivative, and murine embryonic fibroblast cells that lack Tsc1 or -2 and respective controls.
  • Global gene expression analysis was performed in the angiomyolipoma and derivative cell lines.

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  • (PMID = 19395678.001).
  • [ISSN] 1535-4989
  • [Journal-full-title] American journal of respiratory cell and molecular biology
  • [ISO-abbreviation] Am. J. Respir. Cell Mol. Biol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / 1P01CA120964; United States / NCI NIH HHS / CA / 1R01CA118764-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Multiprotein Complexes; 0 / Neuropeptides; 0 / Proteins; 0 / RHEB protein, human; 0 / RNA, Messenger; 0 / RNA, Small Interfering; 0 / Tissue Inhibitor of Metalloproteinases; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 0 / mechanistic target of rapamycin complex 1; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein; EC 2.7.- / Protein Kinases; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.1.1 / mTOR protein, mouse; EC 3.4.24.24 / MMP2 protein, human; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.6.5.2 / Monomeric GTP-Binding Proteins; W36ZG6FT64 / Sirolimus
  • [Other-IDs] NLM/ PMC2822984
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99. Medda M, Picozzi SC, Bozzini G, Carmignani L: Wunderlich's syndrome and hemorrhagic shock. J Emerg Trauma Shock; 2009 Sep;2(3):203-5
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  • Since the first embolization of a renal angiomyolipoma in 1976 by Moorhead et al., highly selective renal arterial embolization of angiomyolipoma with rupture has become a procedure that offers greater efficacy, particularly in life-threatening cases.

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  • (PMID = 20009313.001).
  • [ISSN] 0974-519X
  • [Journal-full-title] Journal of emergencies, trauma, and shock
  • [ISO-abbreviation] J Emerg Trauma Shock
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2776371
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100. Xiao W, Zhou M, Lou H, Wang Z, Zhang M: Hemodynamic characterization of hepatic angiomyolipoma with least amount of fat evaluated by contrast-enhanced magnetic resonance angiography. Abdom Imaging; 2010 Apr;35(2):203-7
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  • [Title] Hemodynamic characterization of hepatic angiomyolipoma with least amount of fat evaluated by contrast-enhanced magnetic resonance angiography.
  • The purpose of our study was to describe contrast-enhanced magnetic resonance angiography (MRA) findings of hepatic angiomyolipoma (AML) with less lipocyte.
  • [MeSH-major] Angiomyolipoma / pathology. Liver Neoplasms / pathology. Magnetic Resonance Angiography / methods. Neovascularization, Pathologic / pathology

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  • (PMID = 19319591.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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