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1. Cortés JJ, Bernabé JM, Riera N, Arenas JJ: [Intracranial cavernous angioma.]. Radiologia; 2009 Mar-Apr;51(2):190-3
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  • [Title] [Intracranial cavernous angioma.].
  • [Transliterated title] Angiomas cavernosos intracraneales.
  • Urgent CT and posterior MRI examination showed multiple supratentorial and infratentorial cavernous angiomas, one of which was located in the brainstem and presented acute hemorrhage, causing the symptoms.
  • The patient was initially managed conservatively, but the cavernous angioma in the brainstem was surgically extirpated after the patient's condition progressively worsened.
  • [MeSH-major] Brain Neoplasms. Hemangioma, Cavernous

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  • (PMID = 19286234.001).
  • [ISSN] 0033-8338
  • [Journal-full-title] Radiología
  • [ISO-abbreviation] Radiologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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2. Santos-Ditto RA, Santos-Franco JA, Pinos-Gavilanes MW: [Cavernous angioma of the second cranial nerve and chiasmatic apoplexy]. Neurocirugia (Astur); 2007 Feb;18(1):47-51
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  • [Title] [Cavernous angioma of the second cranial nerve and chiasmatic apoplexy].
  • [Transliterated title] Angioma cavernoso del segundo nervio craneal y apoplejía quiasmática.
  • Cavernous angioma was diagnosed by histopathology.
  • Cavernous angiomas constitute nearly 15% of all central nervous system vascular malformations.
  • [MeSH-major] Hemangioma, Cavernous / complications. Optic Chiasm / blood supply. Optic Nerve Neoplasms / complications. Stroke / etiology

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  • (PMID = 17393047.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 35
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3. Zakaria MA, Abdullah JM, George JP, Mutum SS, Lee NN: Third ventricular cavernous angioma. Med J Malaysia; 2006 Jun;61(2):229-32
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  • [Title] Third ventricular cavernous angioma.
  • Third ventricular cavernous angiomas are rare vascular malformations of the brain.
  • We report an eight-year old boy with a rare third ventricular cavernous angioma that hemorrhaged presenting with symptoms of acute hydrocephalus.
  • [MeSH-major] Central Nervous System Neoplasms / diagnosis. Hemangioma, Cavernous, Central Nervous System / diagnosis. Third Ventricle

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  • (PMID = 16898318.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Malaysia
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4. Kim JS, Yang SH, Kim MK, Hong YK: Cavernous angioma in the falx cerebri: a case report. J Korean Med Sci; 2006 Oct;21(5):950-3
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  • [Title] Cavernous angioma in the falx cerebri: a case report.
  • Intracranial cavernous angiomas are benign vascular malformations and can be divided into intra-axial and extra-axial lesions.
  • Extra-axial cavernous angiomas are relatively rare and usually arise in relation to the dura mater and mimick meningiomas.
  • We report a case of cavernous angioma that occurred in the falx cerebri of a 22-yr-old female patient with the special focus on neuroradiologic findings.
  • This is the fourth case of cavernous angioma in the falx cerebri reported in the literature to our knowledge.
  • [MeSH-major] Dura Mater / pathology. Hemangioma, Cavernous / radiography. Meningeal Neoplasms / radiography

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  • (PMID = 17043437.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2722013
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5. Chun SW, Kim SJ, Lee TH, Koo HS: Intra-root cavernous angioma of the cauda equina : a case report and review of the literature. J Korean Neurosurg Soc; 2010 Apr;47(4):291-4

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  • [Title] Intra-root cavernous angioma of the cauda equina : a case report and review of the literature.
  • Authors experienced intra-root cavernous angioma which is very rare case among cavernous angiomas of cauda equina.
  • Our intra-root cavernous angioma was confirmed by findings from operating field and microscopic examination.

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  • (PMID = 20461171.001).
  • [ISSN] 1598-7876
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2864823
  • [Keywords] NOTNLM ; Cauda equina / Cavernous angioma / Intra-root cavernous angioma
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6. Mathews MS, Peck WW, Brant-Zawadzki M: Brown-Séquard syndrome secondary to spontaneous bleed from postradiation cavernous angiomas. AJNR Am J Neuroradiol; 2008 Nov;29(10):1989-90
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  • [Title] Brown-Séquard syndrome secondary to spontaneous bleed from postradiation cavernous angiomas.
  • We report a rare case of Brown-Séquard syndrome from spontaneous intraspinal hemorrhage in a patient with multiple cavernous angiomas in the spinal cord secondary to craniospinal radiation in childhood.
  • [MeSH-major] Brown-Sequard Syndrome / diagnosis. Brown-Sequard Syndrome / etiology. Cerebral Hemorrhage / diagnosis. Cerebral Hemorrhage / etiology. Hemangioma, Cavernous / complications. Neoplasms, Radiation-Induced / complications. Radiotherapy / adverse effects

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  • (PMID = 18617590.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Revert Ventura AJ, Martí-Bonmatí L, Poyatos Ruipérez C, Pallardó Calatayud Y, Arana E, Mollá Olmos E: [Association of cavernous and venous angiomas]. Neurologia; 2007 Dec;22(10):839-45
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  • [Title] [Association of cavernous and venous angiomas].
  • [Transliterated title] Asociación de angiomas cavernosos con venosos.
  • INTRODUCTION: Isolated cavernous and venous angiomas are common vascular cerebral malformations.
  • OBJECTIVE: An analysis of the association characteristics of both lesions (cavernous and venous angiomas), and the relationships with localization, size, patient sex and the use of intravenous contrast material in the diagnosis with MR.
  • METHODS: A retrospective analysis of the cerebral MRI studies of 37 patients with cavernous angiomas.
  • Results. 52 cavernous angiomas were identified in the 37 patients.
  • No significant statistical differences were found that related the cavernous angioma size, localization or patient sex with the existence of an associated venous angioma.
  • CONCLUSIONS: The association of cavernous and venous angioma is frequent (30%).
  • To detect venous angiomas is necessary the administration of contrast material.
  • [MeSH-major] Brain / blood supply. Brain Neoplasms / diagnosis. Hemangioma / diagnosis. Hemangioma, Cavernous / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 17671855.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Editorial; English Abstract
  • [Publication-country] Spain
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8. Yagi K, Kageji T, Nagahiro S, Murayama Y: Multiple cystic cavernous angiomas associated with hemorrhage. Acta Neurochir (Wien); 2005 Feb;147(2):201-3; discussion 203

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  • [Title] Multiple cystic cavernous angiomas associated with hemorrhage.
  • The histological diagnosis was cavernous angioma.
  • The first report of multiple cystic cavernous angiomas is reported.
  • [MeSH-major] Brain / pathology. Central Nervous System Cysts / complications. Cerebral Hemorrhage / etiology. Cerebral Hemorrhage / pathology. Hemangioma, Cavernous, Central Nervous System / complications. Hemangioma, Cavernous, Central Nervous System / pathology

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  • (PMID = 15365796.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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9. Nishikawa M, Ohata K, Ishibashi K, Takami T, Goto T, Hara M: The anterolateral partial vertebrectomy approach for ventrally located cervical intramedullary cavernous angiomas. Neurosurgery; 2006 Jul;59(1 Suppl 1):ONS58-63; discussion ONS58-63
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  • [Title] The anterolateral partial vertebrectomy approach for ventrally located cervical intramedullary cavernous angiomas.
  • OBJECTIVE: We report three cases with ventral cervical intramedullary cavernous angiomas.
  • MATERIALS AND METHODS: All three patients presented with numbness in the upper extremities and investigation revealed a cavernous angioma on the ventral aspect of the spinal cord in each case.
  • RESULTS: Complete resection of the cavernous angioma was performed in all patients.
  • CONCLUSION: Anterolateral partial vertebrectomy provides direct exposure and is probably an ideal approach for selected cases with ventrally located intramedullary cavernous angiomas.
  • [MeSH-major] Cervical Vertebrae / surgery. Hemangioma, Cavernous, Central Nervous System / surgery. Neurosurgical Procedures / methods. Spinal Cord Neoplasms / surgery. Vascular Surgical Procedures / methods

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  • (PMID = 16888552.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Santoro A, Piccirilli M, Bristot R, di Norcia V, Salvati M, Delfini R: Extradural spinal cavernous angiomas: report of seven cases. Neurosurg Rev; 2005 Oct;28(4):313-9
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  • [Title] Extradural spinal cavernous angiomas: report of seven cases.
  • The authors describe seven cases of extradural spinal cavernous angioma.
  • In all cases histological diagnosis was cavernous angioma.
  • [MeSH-major] Hemangioma, Cavernous / pathology. Spinal Neoplasms / pathology

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  • (PMID = 15926084.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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11. Sarikaya-Seiwert S, Gierga K, Wessalowski R, Steiger HJ, Hänggi D: Solitary spinal epidural cavernous angiomas in children presenting with acute neurological symptoms caused by hemorrhage. J Neurosurg Pediatr; 2010 Jan;5(1):89-93

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  • [Title] Solitary spinal epidural cavernous angiomas in children presenting with acute neurological symptoms caused by hemorrhage.
  • Spinal solitary epidural cavernous angiomas are rare benign vascular malformations, which occur even less frequently in children than in adults.
  • In this report the authors describe 2 children presenting with acute symptoms and neurological deficits caused by hemorrhage within solitary spinal epidural cavernous angiomas.
  • The histological examination of the lesions revealed the characteristic structures of a cavernous angioma with hemosiderin deposits and acute hemorrhage.
  • Review of the literature confirmed that spinal epidural cavernous angiomas are extremely rare in the pediatric patient population, described currently in only 2 instances, but without acute hemorrhage.
  • These cases suggest that epidural cavernous angiomas also have to be considered in the pediatric patient population in the differential diagnosis of intraspinal lesions with acute or progressive neurological symptoms.
  • Microsurgical resection of these cavernous malformations is an effective and curative treatment option.
  • [MeSH-major] Epidural Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / surgery

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  • (PMID = 20043742.001).
  • [ISSN] 1933-0715
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Gamrot J, Bazowski P, Rudnik A, Zawadzki T: [Cavernous angiomas in the Department of Neurosurgery in Katowice]. Wiad Lek; 2005;58(11-12):595-7
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  • [Title] [Cavernous angiomas in the Department of Neurosurgery in Katowice].
  • There were 30 (18%) patients diagnosed as cavernous angioma (CA).
  • [MeSH-major] Brain Neoplasms / epidemiology. Hemangioma, Cavernous / epidemiology

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  • (PMID = 16594466.001).
  • [ISSN] 0043-5147
  • [Journal-full-title] Wiadomości lekarskie (Warsaw, Poland : 1960)
  • [ISO-abbreviation] Wiad. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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13. Lim SC, Hong R, Kim YS, Jang SJ: Large cystic cavernous angioma of the cerebellum mimicking pilocytic astrocytoma. J Neurooncol; 2006 Sep;79(2):169-70
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  • [Title] Large cystic cavernous angioma of the cerebellum mimicking pilocytic astrocytoma.
  • OBJECTIVE AND IMPORTANCE: Cavernous angiomas are relatively rare vascular malformations.
  • Cavernous angiomas, accompanied by a large cyst, are very rare.
  • We present a case of a cavernous angioma with the unusual MRI findings of a large cyst and a small mural nodule.
  • Therefore, a rare cystic angioma must be considered in the differential diagnosis of infratentorial cystic masses.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Central Nervous System Cysts / diagnosis. Cerebellum / pathology. Hemangioma, Cavernous, Central Nervous System / diagnosis

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  • (PMID = 16821089.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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14. Melone AG, Delfinis CP, Passacantilli E, Lenzi J, Santoro A: Intracranial extra-axial cavernous angioma of the cerebellar falx. World Neurosurg; 2010 Oct-Nov;74(4-5):501-4
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  • [Title] Intracranial extra-axial cavernous angioma of the cerebellar falx.
  • INTRODUCTION: Intracranial cavernous hemangiomas are benign vascular malformations that can be divided into intra-axial and extra-axial types.
  • Extra-axial cavernous angiomas (or hemangiomas) are rare lesions; intracranially, they arise in relation to the dura mater or at a spinal level mimicking meningiomas.
  • CASE REPORT: The authors report a case of a cavernous angioma that occurred in the cerebellar falx of a 58-year-old man.
  • CONCLUSION: Intra-axial and extra-axial cavernous angiomas are histopathologically identical lesions, but by the radiological features, it is very difficult to distinguish the extra-axial cavernous angiomas from meningiomas, especially when dural tail sign and calcification are present.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Dura Mater / pathology. Hemangioma, Cavernous, Central Nervous System / pathology. Infratentorial Neoplasms / pathology. Meningeal Neoplasms / pathology

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21492602.001).
  • [ISSN] 1878-8769
  • [Journal-full-title] World neurosurgery
  • [ISO-abbreviation] World Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Ohba S, Shimizu K, Shibao S, Nakagawa T, Murakami H: Cystic cavernous angiomas. Neurosurg Rev; 2010 Oct;33(4):395-400
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  • [Title] Cystic cavernous angiomas.
  • Cystic cavernous angiomas are rarely found in patients.
  • We have reviewed 25 cases of cystic cavernous angiomas, including our case.
  • The cystic cavernous angiomas were located in the supratentorial region in 16 (64%) cases, the cerebellopontine angle in 4 (16%) cases, and the cerebellum in 5 (20%) cases.
  • [MeSH-major] Brain Neoplasms / surgery. Central Nervous System Cysts / surgery. Hemangioma, Cavernous / surgery

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  • (PMID = 20174956.001).
  • [ISSN] 1437-2320
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
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16. Kazim SF, Bhatti, Enam SA: Intracranial cavernous angiomas. J Coll Physicians Surg Pak; 2010 Nov;20(11):738-43
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  • [Title] Intracranial cavernous angiomas.
  • OBJECTIVE: To describe the clinical presentation, diagnosis, and management of patients presenting with intracranial cavernous angiomas (CAs) at a tertiary care hospital in Pakistan.
  • [MeSH-major] Brain Neoplasms / surgery. Hemangioma, Cavernous / surgery

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  • (PMID = 21078247.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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17. Capelle HH, Nakamura M, Lenarz T, Brandis A, Haubitz B, Krauss JK: Cavernous angioma of the geniculate ganglion. J Neurosurg; 2008 Nov;109(5):893-6
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  • [Title] Cavernous angioma of the geniculate ganglion.
  • Intracranial extraaxial cavernous angiomas are rare vascular malformations.
  • Histological examination revealed a cavernous angioma.
  • [MeSH-major] Cranial Nerve Neoplasms / diagnosis. Geniculate Ganglion. Hemangioma, Cavernous / diagnosis

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  • (PMID = 18976080.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Narisawa A, Kumabe T, Anzai T, Utsumi Y, Tominaga T: [A case of cavernous angioma at the septum pellucidum]. No Shinkei Geka; 2007 Jan;35(1):53-8
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  • [Title] [A case of cavernous angioma at the septum pellucidum].
  • A 35-year-old female presented with a cavernous angioma of the septum pellucidum manifesting as headache and nausea.
  • The histological diagnosis was cavernous angioma.
  • Cavernous angiomas are usually located in the cerebral parenchyma and rarely occur in the cerebral ventricles.
  • In particular, cavernous angioma at the septum pellucidum is very rare.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / surgery. Septum Pellucidum

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  • (PMID = 17228768.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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19. Seet RC, Lim EC: Symptomatic segmental dystonia from a cavernous angioma in the centrum semiovale. Parkinsonism Relat Disord; 2005 Jan;11(1):65-7
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  • [Title] Symptomatic segmental dystonia from a cavernous angioma in the centrum semiovale.
  • EEG and MRI of the cervical spine were unremarkable, but MRI of the brain revealed a small cavernous angioma measuring one centimeter in diameter in the left centrum semiovale.
  • Arteriovenous malformations have been described to cause movement disorders, but dystonia has not previously been reported in association with cavernous angiomas.
  • A search of the literature revealed one report of a patient with chorea arising from a cavernous angioma.
  • This interesting case illustrates how an uncomplicated cavernous angioma can rarely cause segmental dystonia and highlights the importance of neuroimaging in patients with late-onset movement disorders.
  • [MeSH-major] Brain Neoplasms / complications. Dystonia / etiology. Hemangioma, Cavernous / complications

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  • (PMID = 15619465.001).
  • [ISSN] 1353-8020
  • [Journal-full-title] Parkinsonism & related disorders
  • [ISO-abbreviation] Parkinsonism Relat. Disord.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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20. Ozer E, Yücesoy K, Kalemci O: Demonstrated rapid growth of a corpus callosum cavernous angioma within a short period of time. J Neurosurg Sci; 2005 Dec;49(4):155-8; discussion 158
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Demonstrated rapid growth of a corpus callosum cavernous angioma within a short period of time.
  • Cavernous angiomas are uncommon central nervous system vascular malformations.
  • In this study we report a case of corpus callosum cavernous angioma which demonstrated rapid growth within a short period of time.
  • Corpus callosum cavernous angiomas have distinct features regarding growth and should be treated more carefully by giving more importance to surgical removal rather than a conservative approach.
  • [MeSH-major] Brain Neoplasms / pathology. Corpus Callosum / pathology. Hemangioma, Cavernous, Central Nervous System / pathology

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  • (PMID = 16374407.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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21. Wu MC, Luo SQ, Xie J, Ma ZY, Zhang YQ, Jia G: [Supratentorial cavernous angiomas in children]. Zhonghua Yi Xue Za Zhi; 2006 Feb 7;86(5):329-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Supratentorial cavernous angiomas in children].
  • OBJECTIVE: To discuss the clinical features, treatment, and prognosis of supratentorial cavernous angiomas in children.
  • METHODS: The clinical data of 25 pediatric patients with supratentorial cavernous angioma, 17 boys and 6 girls, aged 9.6 (1-15), were reviewed retrospectively, and the relationship between the duration of epilepsy before surgery and prognosis was analyzed.
  • [MeSH-major] Hemangioma, Cavernous, Central Nervous System / surgery. Supratentorial Neoplasms / surgery

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  • (PMID = 16677527.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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22. Marasco R, Spagnoli M, Leonardi M: Association between Developmental Venous Anomalies and Cavernous Angiomas: a Retrospective MR Study. Neuroradiol J; 2009 May 15;22(2):179-85

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association between Developmental Venous Anomalies and Cavernous Angiomas: a Retrospective MR Study.
  • Many studies suggested and then confirmed the association between cavernous angioma and developmental venous anomaly, described for the first time by Roberson in 1974.
  • The aim of our study was a retrospective assessment of the case series at our institution, namely to determine the frequency of the association between developmental venous anomaly and cavernous and analyse the relation between the two lesions.

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  • (PMID = 24207037.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Kan P, Tubay M, Osborn A, Blaser S, Couldwell WT: Radiographic features of tumefactive giant cavernous angiomas. Acta Neurochir (Wien); 2008 Jan;150(1):49-55; discussion 55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiographic features of tumefactive giant cavernous angiomas.
  • BACKGROUND: Giant cavernous angiomas (GCAs) are very rare, and imaging features of GCAs can be very different from those of typical cavernous angiomas (CAs), making them a diagnostic challenge.
  • [MeSH-major] Brain Neoplasms / diagnosis. Hemangioma, Cavernous / diagnosis

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  • (PMID = 18066488.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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24. Carrasco R, Pedrosa M, Pascual JM, Navas M, Liberal R, Sola RG: Cavernous angiomas of the lateral ventricles. Acta Neurochir (Wien); 2009 Feb;151(2):149-54

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous angiomas of the lateral ventricles.
  • BACKGROUND: Cavernous angiomas are vascular malformations which rarely involve the cavities of the lateral ventricles.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Hemangioma, Cavernous, Central Nervous System / pathology. Lateral Ventricles / pathology

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  • (PMID = 19194650.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
  • [Number-of-references] 42
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25. Samii M, Nakamura M, Mirzai S, Vorkapic P, Cervio A: Cavernous angiomas within the internal auditory canal. J Neurosurg; 2006 Oct;105(4):581-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous angiomas within the internal auditory canal.
  • OBJECT: The aim of this study was to describe the symptomatology, radiological features, and surgical treatment of patients with cavernous angiomas within the internal auditory canal (IAC).
  • METHODS: The authors reviewed the cases of seven patients with cavernous angiomas in the IAC that had been surgically treated in the 22-year period between 1983 and 2005.
  • Interestingly, these same angiomas showed variable features on magnetic resonance (MR) imaging, making their differentiation from intrameatal vestibular schwannomas (VSs) sometimes impossible.
  • CONCLUSIONS: Cavernous angiomas of the IAC are very uncommon lesions that can imitate the symptoms of VSs.
  • [MeSH-major] Ear Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / surgery. Labyrinth Diseases / surgery

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  • (PMID = 17044562.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 47
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26. Shalek PA, Vinogradov BM, Pozdniakov AV, Stukov LA, Garmashov IuA: [Methods and results of stereotactic radiosurgery for cavernous angiomas]. Vopr Onkol; 2008;54(4):525-8
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  • [Title] [Methods and results of stereotactic radiosurgery for cavernous angiomas].
  • They presented with 47 cavernous angiomas and 44 of them underwent surgery.
  • [MeSH-major] Brain Neoplasms / surgery. Hemangioma, Cavernous / surgery. Radiosurgery

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  • (PMID = 18942415.001).
  • [ISSN] 0507-3758
  • [Journal-full-title] Voprosy onkologii
  • [ISO-abbreviation] Vopr Onkol
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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27. Noto S, Fujii M, Akimura T, Imoto H, Nomura S, Kajiwara K, Kato S, Fujisawa H, Suzuki M: Management of patients with cavernous angiomas presenting epileptic seizures. Surg Neurol; 2005 Dec;64(6):495-8, discussion 498-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of patients with cavernous angiomas presenting epileptic seizures.
  • BACKGROUND: The aim of this study was to establish a treatment strategy for patients with cavernous angiomas and have seizures.
  • METHODS: We analyzed retrospectively 31 patients with cavernous angiomas presenting with seizures.
  • CONCLUSIONS: Surgical intervention may have greater benefits than medical intervention for patients with cavernous angiomas presenting with epileptic seizures.
  • [MeSH-major] Hemangioma, Cavernous / complications. Hemangioma, Cavernous / surgery. Seizures / etiology

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  • (PMID = 16293460.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants
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28. Toldo I, Drigo P, Mammi I, Marini V, Carollo C: Vertebral and spinal cavernous angiomas associated with familial cerebral cavernous malformation. Surg Neurol; 2009 Feb;71(2):167-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vertebral and spinal cavernous angiomas associated with familial cerebral cavernous malformation.
  • BACKGROUND: Cerebral cavernous malformations are vascular malformations that affect the CNS and have been associated with cutaneous, retinal, and hepatic lesions.
  • The coexistence of intracranial and spinal cavernous angiomas in familial CCM is extremely rare.
  • In addition to previous studies, the occurrence of spinal, vertebral, and cutaneous cavernous angiomas is now described in different members of a large family with CCM.
  • CASE DESCRIPTION: Our study reports a previously described family (IFCAS-07) with 12 members affected by autosomal dominant cavernous angiomas: 11 had CCM either alone or associated with hepatic or retinal angiomas, and one had only hepatic angioma.
  • Spinal MRI showed in 5 subjects spinal cavernous angiomas either alone or associated with vertebral hemangiomas.
  • CONCLUSIONS: To our knowledge, this is the largest family reported with different subjects affected by CCM associated with multiple cavernous angiomas throughout (brain and spinal cord) and besides (retina, skin, liver, and vertebral column) the CNS.
  • We emphasize the importance of spinal MRI in the diagnosis of spinal and vertebral cavernous angiomas in all patients affected by familial CCM.
  • [MeSH-major] Central Nervous System Neoplasms / etiology. Central Nervous System Vascular Malformations / complications. Hemangioma, Cavernous / etiology. Spinal Neoplasms / etiology

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  • (PMID = 18207546.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / KRIT1 protein, human; 0 / Microtubule-Associated Proteins; 0 / Proto-Oncogene Proteins
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29. Kobayashi E, Bagshaw AP, Gotman J, Dubeau F: Metabolic correlates of epileptic spikes in cerebral cavernous angiomas. Epilepsy Res; 2007 Jan;73(1):98-103
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metabolic correlates of epileptic spikes in cerebral cavernous angiomas.
  • BACKGROUND: Cerebral cavernous angiomas (CCA) are frequently associated with focal intractable epilepsy.
  • [MeSH-major] Brain Neoplasms / physiopathology. Epilepsy, Temporal Lobe / etiology. Hemangioma, Cavernous / physiopathology. Seizures / physiopathology

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  • (PMID = 17000081.001).
  • [ISSN] 0920-1211
  • [Journal-full-title] Epilepsy research
  • [ISO-abbreviation] Epilepsy Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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30. Kumar GS, Poonnoose SI, Chacko AG, Rajshekhar V: Trigonal cavernous angiomas: report of three cases and review of literature. Surg Neurol; 2006 Apr;65(4):367-71, discussion 371
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Trigonal cavernous angiomas: report of three cases and review of literature.
  • BACKGROUND: Intraventricular cavernous angiomas are very rare.
  • Only few cases of trigonal angiomas have been reported.
  • CASE DESCRIPTION: We report three cases of trigonal cavernous angiomas who presented with raised intracranial pressure or seizures and who underwent total excision with a good recovery.
  • CONCLUSION: On magnetic resonance imaging, intraventricular cavernous angiomas lack the hemosiderin ring characteristically seen around parenchymal cavernous angiomas.
  • This explains why trigonal cavernous angiomas can mimic malignant neoplasm on imaging, and they should be considered in the differential diagnosis of intraventricular masses.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / diagnosis. Hemangioma, Cavernous, Central Nervous System / surgery. Lateral Ventricles / pathology. Lateral Ventricles / surgery

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  • (PMID = 16531197.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Huo L, Wu L, Zhang MY, Hou YH, Ding XP, Fang JS: [Electrocorticography monitoring in microsurgical treatment of solitary cavernous angiomas]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2008 May;33(5):448-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Electrocorticography monitoring in microsurgical treatment of solitary cavernous angiomas].
  • OBJECTIVE: To investigate the curative effect of electrocorticography (ECoG) monitoring in the microsurgical treatment of cavernous angiomas.
  • METHODS: Clinical data of 71 patients with epileptogenic cavernous angiomas,who had been performed ECoG monitoring during the operation,were analyzed retrospectively.
  • RESULTS: The foci of cavernous angiomas and epilepsy of the 71 patients were resected during the operation.
  • CONCLUSION: The drug treatment of epileptogenic cavernous angiomas can not control epileptic seizure,and the patients should receive the microsurgical treatment early.
  • [MeSH-major] Cerebral Cortex / physiopathology. Electroencephalography. Hemangioma, Cavernous, Central Nervous System / surgery. Microsurgery / methods. Monitoring, Intraoperative / methods

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  • (PMID = 18544851.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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32. Caruso G, Galarza M, Borghesi I, Pozzati E, Vitale M: Acute presentation of spinal epidural cavernous angiomas: case report. Neurosurgery; 2007 Mar;60(3):E575-6; discussion E576

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acute presentation of spinal epidural cavernous angiomas: case report.
  • OBJECTIVE: Spinal extramedullary hematomas stemming from cavernous angiomas in the epidural compartment are rare.
  • It is more common for spinal epidural cavernous angiomas to present with slow and progressive myelopathy or radiculopathy.
  • CLINICAL PRESENTATION: Three consecutive cases of acute spinal cavernous angiomas with overt neurological deficits were presented.
  • The cases included either abrupt lesion enlargement secondary to a pure intralesional hemorrhage or a cavernous hemorrhage that invaded the epidural space.
  • CONCLUSION: Spontaneous spinal epidural hematomas presented with significant pain and acute spinal cord and nerve root compression may represent the manifestation of a cavernous angioma.
  • [MeSH-major] Epidural Neoplasms / diagnosis. Epidural Neoplasms / surgery. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / surgery

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  • (PMID = 17327768.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Miyake S, Uchihashi Y, Takaishi Y, Sakagami Y, Kohmura E: Multiple cavernous angiomas of the cauda equina. Case report. Neurol Med Chir (Tokyo); 2007 Apr;47(4):178-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple cavernous angiomas of the cauda equina. Case report.
  • An 18-year-old male presented with multiple cavernous angiomas of the cauda equina manifesting as acute onset of severe low back pain radiating into the bilateral legs.
  • Histological examination revealed cavernous angioma.
  • [MeSH-major] Cauda Equina. Hemangioma, Cavernous / diagnosis. Peripheral Nervous System Neoplasms / diagnosis

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  • (PMID = 17457023.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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34. Bernotas G, Rastenyte D, Deltuva V, Matukevicius A, Jaskeviciene V, Tamasauskas A: Cavernous angiomas: an uncontrolled clinical study of 87 surgically treated patients. Medicina (Kaunas); 2009;45(1):21-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous angiomas: an uncontrolled clinical study of 87 surgically treated patients.
  • BACKGROUND: Cerebral cavernous angiomas remain as one of the most negotiable and controversial topics in neurological and neurosurgical practice.
  • We present statistical evaluation of initial presentation, preoperative neurological findings, surgical complications, and outcome of surgically treated patients with intracerebral cavernous angiomas.
  • METHODS: During 1997 to 2004, 87 patients (41 men, 46 women) with intracerebral cavernous angiomas underwent surgical treatment in the tertiary referral center, and these were included into the present uncontrolled clinical study.
  • RESULTS: The most common clinical presentation of cavernous angiomas was seizures, significant part of which was chronic.
  • CONCLUSIONS: Microsurgical removal of cavernous angiomas and surrounding hemosiderin plate tends to significant reduction or elimination of epileptic seizures and improved postoperative neurological status.
  • [MeSH-major] Brain Neoplasms / surgery. Hemangioma, Cavernous / surgery. Neoplasms, Multiple Primary / surgery

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  • (PMID = 19223702.001).
  • [ISSN] 1648-9144
  • [Journal-full-title] Medicina (Kaunas, Lithuania)
  • [ISO-abbreviation] Medicina (Kaunas)
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Lithuania
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35. Labauge P, Denier C, Bergametti F, Tournier-Lasserve E: Genetics of cavernous angiomas. Lancet Neurol; 2007 Mar;6(3):237-44

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetics of cavernous angiomas.
  • Cerebral cavernous malformations (CCM) are vascular malformations that can occur as a sporadic or a familial autosomal dominant disorder.
  • [MeSH-major] Hemangioma, Cavernous / genetics

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  • (PMID = 17303530.001).
  • [ISSN] 1474-4422
  • [Journal-full-title] The Lancet. Neurology
  • [ISO-abbreviation] Lancet Neurol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 84
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36. Yun TJ, Na DG, Kwon BJ, Rho HG, Park SH, Suh YL, Chang KH: A T1 hyperintense perilesional signal aids in the differentiation of a cavernous angioma from other hemorrhagic masses. AJNR Am J Neuroradiol; 2008 Mar;29(3):494-500
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A T1 hyperintense perilesional signal aids in the differentiation of a cavernous angioma from other hemorrhagic masses.
  • BACKGROUND AND PURPOSE: A cavernous angioma is a developmental vascular malformation with a high risk of hemorrhage.
  • The purpose of this work was to retrospectively determine whether an MR sign of T1 hyperintense perilesional signal intensity is useful for the differentiation of cavernous angioma from other hemorrhagic cerebral masses.
  • We retrospectively evaluated the MR images of 72 patients with acute or subacute cerebral hemorrhagic lesions with perilesional edema (29 cavernous angiomas, 13 glioblastomas, 1 oligodendroglioma, 16 metastatic tumors, and 13 intracerebral hemorrhages) for the presence of T1 hyperintense perilesional signal intensity.
  • In cavernous angiomas, volumes of hemorrhagic lesions and perilesional edemas, lesion locations, presence of contrast enhancement, and time intervals between symptom onset and MR imaging were also assessed.
  • RESULTS: T1 hyperintense perilesional signal intensity sign was found in 18 (62.1%) of 29 cavernous angiomas, in 1 (6.3%) of 16 metastases, and in 0 primary brain tumors or intracerebral hemorrhages.
  • Sensitivity, specificity, and positive predictive value of this sign for cavernous angioma were 62%, 98%, and 95%, respectively.
  • The perilesional T1 hyperintensity was significantly higher in cavernous angiomas (P = .045) than in normal white matter.
  • Perilesional edema volumes were larger in cavernous angiomas with the MR sign than in cavernous angiomas without the sign (P = .009).
  • CONCLUSION: When the MR sign of T1 hyperintense perilesional signal intensity is present, there is a high probability of cavernous angioma being present in the brain, and this MR sign may be helpful for differentiating cavernous angioma from hemorrhagic tumors and intracerebral hemorrhages.
  • [MeSH-major] Brain Neoplasms / diagnosis. Cerebral Hemorrhage / diagnosis. Hemangioma, Cavernous / diagnosis. Image Enhancement / methods. Magnetic Resonance Imaging / methods


37. Cantu C, Murillo-Bonilla L, Arauz A, Higuera J, Padilla J, Barinagarrementeria F: Predictive factors for intracerebral hemorrhage in patients with cavernous angiomas. Neurol Res; 2005 Apr;27(3):314-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictive factors for intracerebral hemorrhage in patients with cavernous angiomas.
  • OBJECTIVES: Prediction of intracerebral hemorrhage (ICH) in patients with cavernous angiomas is not totally elucidated.
  • The aims of our study were to determine the rate of cerebral hemorrhage, its associated factors, and the clinical outcome in patients with cavernous angiomas in a Hispanic population.
  • METHODS: We studied 133 patients with cavernous angiomas.
  • Non-lobar location of angiomas was associated with hemorrhage [OR 4.82 (CI 95% 2.17-10.73; p=<0.001)].
  • In contrast, factors associated with a decreased risk of hemorrhage were a family history of epilepsy [OR 0.30 (CI 95% 0.10-0.79; p=0.016)] and lobar location of the angiomas [OR 0.21 (CI 95% 0.09-0.46; p=<0.001)].
  • It was only 1.22% per patient per year in lobar angiomas and 2.33, 2.39, and 2.82% per patient per year for brainstem, cerebellum, and deep hemispheric angiomas, respectively.
  • CONCLUSIONS: The non-lobar location of cavernous angiomas gives a higher risk of hemorrhage in our Mexican mestizo population, without the hemorrhage being related to either age or sex.
  • [MeSH-major] Cerebral Hemorrhage / epidemiology. Cerebral Hemorrhage / etiology. Hemangioma, Cavernous / complications. Risk

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  • (PMID = 15845215.001).
  • [ISSN] 0161-6412
  • [Journal-full-title] Neurological research
  • [ISO-abbreviation] Neurol. Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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38. Cenzato M, Stefini R, Ambrosi C, Latronico N, Milani D: Surgical resolution of trigeminal neuralgia due to intra-axial compression by pontine cavernous angioma. World Neurosurg; 2010 Oct-Nov;74(4-5):544-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical resolution of trigeminal neuralgia due to intra-axial compression by pontine cavernous angioma.
  • Few cases of trigeminal neuralgia due to cavernous angiomas have been reported in the literature.
  • This is the first report of surgical decompression of the intra-axial trigeminal nerve tract from a deep pontine cavernous angioma.
  • Magnetic resonance imaging revealed a left posterolateral pontine cavernous angioma.
  • RESULTS: The cavernous angioma was surgically excised.
  • CONCLUSIONS: Trigeminal neuralgia can occur occasionally secondary to the compressive effect of a pontine cavernous angioma.
  • In this patient surgical removal of the cavernous angioma can be considered a successful and relatively safe treatment.
  • [MeSH-major] Brain Stem Neoplasms / complications. Brain Stem Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / complications. Hemangioma, Cavernous, Central Nervous System / surgery. Trigeminal Neuralgia / etiology. Trigeminal Neuralgia / surgery

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21492610.001).
  • [ISSN] 1878-8769
  • [Journal-full-title] World neurosurgery
  • [ISO-abbreviation] World Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Noudel R, Litré F, Vinchon M, Patey M, Rousseaux P: Intramedullary spinal cord cavernous angioma in children: case report and literature review. Childs Nerv Syst; 2008 Feb;24(2):259-63
ORBi (University of Liege). Free full Text at ORBi .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramedullary spinal cord cavernous angioma in children: case report and literature review.
  • INTRODUCTION: Intramedullary cavernous angiomas (ImCA) of the spinal cord are very uncommon malformations especially in the pediatric population where only ten cases have yet been reported within the available literature.
  • CASE REPORT: In this paper, the authors report the case of a 12-year-old girl presenting with a T11 level hematomyelia because of a cavernous angioma.
  • [MeSH-major] Hemangioma, Cavernous / pathology. Hemangioma, Cavernous / surgery. Spinal Cord Neoplasms / pathology. Spinal Cord Neoplasms / surgery

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  • (PMID = 17849122.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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40. Jung YJ, Hong SC, Seo DW, Hong SB: Surgical resection of cavernous angiomas located in eloquent areas--clinical research. Acta Neurochir Suppl; 2006;99:103-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical resection of cavernous angiomas located in eloquent areas--clinical research.
  • In this retrospective study, our techniques for localizing lesion and the postoperative results of 26 patients with cavernous angiomas (CA) located at the eloquent areas are summarized.
  • [MeSH-major] Brain Neoplasms / surgery. Hemangioma, Cavernous / surgery

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  • (PMID = 17370774.001).
  • [ISSN] 0065-1419
  • [Journal-full-title] Acta neurochirurgica. Supplement
  • [ISO-abbreviation] Acta Neurochir. Suppl.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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41. Gelal F, Feran H, Rezanko T, Vidinli BD: Giant cavernous angioma of the temporal lobe: a case report and review of the literature. Acta Radiol; 2005 May;46(3):310-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant cavernous angioma of the temporal lobe: a case report and review of the literature.
  • Cavernous angiomas of the central nervous system are angiographically occult vascular lesions and are easily diagnosed by magnetic resonance imaging (MRI).
  • Giant cavernous angiomas (GCA) are rare, with only 11 cases reported in the literature.
  • Some GCAs have features that are similar to those of typical cavernous angiomas, whereas some lesions may be purely cystic; and some present with significant contrast enhancement and mass effect, mimicking neoplasms.
  • [MeSH-major] Brain Neoplasms / diagnosis. Hemangioma, Cavernous / diagnosis. Temporal Lobe / pathology. Temporal Lobe / radiography

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  • (PMID = 15981729.001).
  • [ISSN] 0284-1851
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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42. Yeon JY, Kim JS, Choi SJ, Seo DW, Hong SB, Hong SC: Supratentorial cavernous angiomas presenting with seizures: surgical outcomes in 60 consecutive patients. Seizure; 2009 Jan;18(1):14-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Supratentorial cavernous angiomas presenting with seizures: surgical outcomes in 60 consecutive patients.
  • The aim of this study is to determine surgical outcomes and factors affecting seizure outcomes in patients who harbor supratentorial cavernous angiomas presenting with seizures.
  • [MeSH-major] Hemangioma, Cavernous, Central Nervous System / surgery. Psychosurgery / methods. Seizures / surgery. Supratentorial Neoplasms / surgery

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  • (PMID = 18656386.001).
  • [ISSN] 1059-1311
  • [Journal-full-title] Seizure
  • [ISO-abbreviation] Seizure
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] England
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43. Zsoldos T, Molnár A, Jánossy A, Kuncz A, Nagy E, Deák G, Barzó P: [Successful surgical removal of a mesencephalic cavernous angioma, which was responsible for progressive neurological deficits]. Ideggyogy Sz; 2008 Jul 30;61(7-8):244-9
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  • [Title] [Successful surgical removal of a mesencephalic cavernous angioma, which was responsible for progressive neurological deficits].
  • Cavernous angiomas comprise 5-10% of all vascular malformations in the central nervous system, occurring most frequently in the supratentorial region, and 20% of them in the brain stem.
  • According to literature, brain stem cavernous angiomas occur most frequently in the pons (60%), and equally in the mesencephalon (20%) and in medulla oblongata.
  • In clinical evaluation the authors describe the successful removal of a mesencephalic cavernous angioma causing progressive neurological deficits and symptoms.
  • [MeSH-major] Ataxia / etiology. Brain Stem Neoplasms / diagnosis. Brain Stem Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / diagnosis. Hemangioma, Cavernous, Central Nervous System / surgery. Mesencephalon. Muscle Weakness / etiology. Peripheral Nervous System Diseases / etiology

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  • (PMID = 18763480.001).
  • [ISSN] 0019-1442
  • [Journal-full-title] Ideggyógyászati szemle
  • [ISO-abbreviation] Ideggyogy Sz
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Hungary
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44. Duffau H, Fontaine D: Successful resection of a left insular cavernous angioma using neuronavigation and intraoperative language mapping. Acta Neurochir (Wien); 2005 Feb;147(2):205-8; discussion 208
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  • [Title] Successful resection of a left insular cavernous angioma using neuronavigation and intraoperative language mapping.
  • Despite recent literature advocating the surgical removal of symptomatic Cavernous Angiomas (CA), even in critical brain areas, very few observations of insular CA surgery have been described, particularly in the left hemisphere.
  • [MeSH-major] Brain Mapping / methods. Cerebral Cortex / pathology. Cerebral Cortex / surgery. Hemangioma, Cavernous, Central Nervous System / pathology. Hemangioma, Cavernous, Central Nervous System / surgery. Neuronavigation / methods

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  • (PMID = 15338338.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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45. Betlej M, Czepko R, Lopatka P, Danilewicz B, Uhl H: [Diagnosis and operative treatment cavernous angiomas of the central nervous system]. Przegl Lek; 2006;63(2):61-3
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  • [Title] [Diagnosis and operative treatment cavernous angiomas of the central nervous system].
  • Among all detected cerebral angiomas the frequency of cavernous angiomas (CAs) is 5-13%.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / diagnosis. Hemangioma, Cavernous, Central Nervous System / surgery

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  • (PMID = 16967711.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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46. Maiuri F, Cappabianca P, Gangemi M, De Caro Mdel B, Esposito F, Pettinato G, de Divitiis O, Mignogna C, Strazzullo V, de Divitiis E: Clinical progression and familial occurrence of cerebral cavernous angiomas: the role of angiogenic and growth factors. Neurosurg Focus; 2006;21(1):e3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical progression and familial occurrence of cerebral cavernous angiomas: the role of angiogenic and growth factors.
  • OBJECT: The authors studied the expression of angiogenic and growth factors and various proliferative indices in cavernous angiomas of the brain.
  • CONCLUSIONS: The familial occurrence and more aggressive clinical behavior of cavernous angiomas of the brain are associated with higher expression of Ki-67 and bcl-2 in the cavernoma tissue, as in other proliferative lesions.
  • [MeSH-major] Angiogenic Proteins / metabolism. Brain Neoplasms / physiopathology. Cerebral Veins / physiopathology. Growth Substances / metabolism. Hemangioma, Cavernous, Central Nervous System / physiopathology. Neovascularization, Pathologic / physiopathology

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  • (PMID = 16859256.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenic Proteins; 0 / Growth Substances; 0 / Ki-67 Antigen; 0 / Platelet-Derived Growth Factor; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Tenascin; 0 / Transforming Growth Factor beta; 0 / Vascular Endothelial Growth Factor A
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47. Tohyama J, Akasaka N, Saito N, Kanazawa O, Morota N, Kameyama S: [An infant with multiple cavernous angiomas presenting with frequent epileptic seizures - detection of epileptic focus by magnetoencephalography]. No To Hattatsu; 2007 Jul;39(4):295-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [An infant with multiple cavernous angiomas presenting with frequent epileptic seizures - detection of epileptic focus by magnetoencephalography].
  • We report on a six-year-old girl with frequent partial seizures secondary to multiple cavernous angiomas (CAs) since the age of 17 months.
  • [MeSH-major] Brain / pathology. Brain Neoplasms / complications. Epilepsies, Partial / diagnosis. Epilepsies, Partial / etiology. Hemangioma, Cavernous / complications. Magnetoencephalography

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  • (PMID = 17633088.001).
  • [ISSN] 0029-0831
  • [Journal-full-title] No to hattatsu. Brain and development
  • [ISO-abbreviation] No To Hattatsu
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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48. Park SB, Jahng TA, Chung CK: The clinical outcomes after complete surgical resection of intramedullary cavernous angiomas: changes in motor and sensory symptoms. Spinal Cord; 2009 Feb;47(2):128-33

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The clinical outcomes after complete surgical resection of intramedullary cavernous angiomas: changes in motor and sensory symptoms.
  • STUDY DESIGN: Evaluation of the surgical effects of patients with intramedullary spinal cord cavernous angiomas (CAs).
  • [MeSH-major] Hemangioma, Cavernous / physiopathology. Hemangioma, Cavernous / surgery. Neurosurgery / methods. Spinal Cord Neoplasms / physiopathology. Spinal Cord Neoplasms / surgery

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  • (PMID = 18663373.001).
  • [ISSN] 1362-4393
  • [Journal-full-title] Spinal cord
  • [ISO-abbreviation] Spinal Cord
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] England
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49. Lenzi J, Seferi A, Nardone A, Salvati M, Vreto G, Santoro A, Raco A, Pichierri A, Petrela M: Sylvian subarachnoid and extra-pial cavernous angioma. J Neurosurg Sci; 2005 Dec;49(4):163-6; discussion 166
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sylvian subarachnoid and extra-pial cavernous angioma.
  • Cavernous angiomas are one of the four types of vascular malformations of the central nervous system.
  • Our case represents an unusual localization of a subarachnoid cavernous angioma.
  • This case represents a radiologically visible supratentorial extra-pial subarachnoidal cavernous angioma.
  • [MeSH-major] Hemangioma, Cavernous / pathology. Subarachnoid Space / pathology. Supratentorial Neoplasms / pathology

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  • (PMID = 16374409.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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50. Tirakotai W, Sure U, Benes L, Krischek B, Bien S, Bertalanffy H: Image-guided transsylvian, transinsular approach for insular cavernous angiomas. Neurosurgery; 2007 Jul;61(1 Suppl):423-30; discussion 430-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Image-guided transsylvian, transinsular approach for insular cavernous angiomas.

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  • [ReprintOf] Neurosurgery. 2003 Dec;53(6):1299-304; discussion 1304-5 [14633296.001]
  • (PMID = 18813148.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Cecchi PC, Rizzo P, Faccioli F, Bontempini L, Schwarz A, Bricolo A: Intraneural cavernous malformation of the cauda equina. J Clin Neurosci; 2007 Oct;14(10):984-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraneural cavernous malformation of the cauda equina.
  • Spinal cavernous angiomas are rare vascular malformations occurring mainly in the vertebral body with or without an extradural extension.
  • The microscopic appearance was suggestive of cavernous angioma with intraneural growth.
  • [MeSH-major] Cauda Equina / pathology. Hemangioma, Cavernous, Central Nervous System / complications. Hemangioma, Cavernous, Central Nervous System / pathology. Polyradiculopathy / etiology. Polyradiculopathy / pathology

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  • (PMID = 17669656.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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52. Puso C, Guillot B, Durand L, Guilhou JJ, Bessis D: [Capillary malformations associated with cerebral cavernous malformation]. Ann Dermatol Venereol; 2005 May;132(5):471-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Capillary malformations associated with cerebral cavernous malformation].
  • [Transliterated title] Malformations capillaires associées à un angiome caverneux cérébral.
  • [MeSH-major] Central Nervous System Vascular Malformations / complications. Central Nervous System Vascular Malformations / pathology. Hemangioma, Cavernous / complications. Hemangioma, Cavernous / pathology

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  • (PMID = 15988361.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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53. Floeth F, Riemenschneider M, Herdmann J: Intralesional hemorrhage and thrombosis without rupture in a pure spinal epidural cavernous angioma: a rare cause of acute lumbal radiculopathy. Eur Spine J; 2010 Jul;19 Suppl 2:S193-6
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  • [Title] Intralesional hemorrhage and thrombosis without rupture in a pure spinal epidural cavernous angioma: a rare cause of acute lumbal radiculopathy.
  • Pure spinal epidural cavernous angiomas are extremely rare lesions, and their normal shape is that of a fusiform mass in the dorsal aspects of the spinal canal.
  • We report a case of a lumbo-sacral epidural cavernous vascular malformation presenting with acute onset of right-sided S1 radiculopathy.
  • Histology revealed a prominent venous vessel with a pathologically thickened, amuscular wall surrounded by smaller, hyalinized, venous vessels arranged in a back-to-back position typical for the diagnosis of a cavernous angioma.
  • In this unique case, the pathologic mechanism was not the usual rupture of the cavernous angioma with subsequent intraspinal hemorrhage, but acute mass effect by intralesional bleedings and thrombosis with subsequent increase of volume leading to nerve root compression.
  • Thus, even without a sudden intraspinal hemorrhage a spinal cavernous malformation can cause acute symptoms identical to the clinical features of a soft disc herniation.
  • [MeSH-major] Hemangioma, Cavernous, Central Nervous System / pathology. Hematoma, Epidural, Spinal / pathology. Lumbar Vertebrae / pathology. Radiculopathy / pathology. Spinal Nerve Roots / pathology. Thrombosis / pathology

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  • (PMID = 20213297.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2899646
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54. Bakir A, Savas A, Yilmaz E, Savaş B, Erden E, Cağlar S, Sener O: Spinal intradural-intramedullary cavernous malformation. Case report and literature review. Pediatr Neurosurg; 2006;42(1):35-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal intradural-intramedullary cavernous malformation. Case report and literature review.
  • Cavernous angiomas or cavernomas are uncommon vascular malformations of the central nervous system and spinal involvement is much rarer especially in pediatric patients.
  • We report a case of spinal intradural-intramedullary cavernous angioma in a 14-year-old male child.
  • [MeSH-major] Hemangioma, Cavernous, Central Nervous System / pathology. Spinal Cord Neoplasms / pathology. Spine / pathology

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  • [Copyright] Copyright 2006 S. Karger AG, Basel
  • (PMID = 16357499.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 8
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55. Adachi K, Yoshida K, Akiyama T, Kawase T: Cavernous angioma of the vestibular nerve: case report and literature review. Surg Neurol; 2008 Jul;70(1):82-6; discussion 86
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous angioma of the vestibular nerve: case report and literature review.
  • BACKGROUND: To date, 50 cases of cavernous angioma in the CPA have been reported, and previous reports did not describe the tumor's site of origin.
  • We describe a case of a small, extraaxial cavernous angioma of the vestibular nerve.
  • We also propose a reclassification system for cavernous angioma of the CPA based on the tumor's site of origin.
  • Magnetic resonance imaging revealed a cavernous angioma of the right CPA.
  • CONCLUSIONS: On the basis of our review of 50 cases of cavernous angioma of the CPA, we propose that these tumors can be classified according to whether they develop from the venous plexus of the dura matter or of a cranial nerve.
  • [MeSH-major] Cranial Nerve Neoplasms / diagnosis. Hemangioma, Cavernous / diagnosis. Vestibular Nerve. Vestibulocochlear Nerve Diseases / diagnosis

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  • (PMID = 18262616.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 3
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56. Tournier-Lasserve E: [Contribution of molecular genetics in cavernous angiomas]. Neurochirurgie; 2007 Jun;53(2-3 Pt 2):136-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Contribution of molecular genetics in cavernous angiomas].
  • [Transliterated title] Apports de la génétique moléculaire dans les angiomes caverneux.
  • [MeSH-major] Central Nervous System Neoplasms / genetics. Hemangioma, Cavernous, Central Nervous System / genetics. Molecular Biology

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  • (PMID = 17507048.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 31
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57. Beall DP, Bell JP, Webb JR, Fish JR: Developmental venous anomalies and cavernous angiomas: a review of the concurrence, imaging, and treatment of these vascular malformations. J Okla State Med Assoc; 2005 Nov;98(11):535-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Developmental venous anomalies and cavernous angiomas: a review of the concurrence, imaging, and treatment of these vascular malformations.
  • Deep venous anomalies and cavernous angiomas are two distinct intracranial lesions.
  • [MeSH-minor] Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / surgery. Humans

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  • (PMID = 16379482.001).
  • [ISSN] 0030-1876
  • [Journal-full-title] The Journal of the Oklahoma State Medical Association
  • [ISO-abbreviation] J Okla State Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
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58. Mori H, Koike T, Endo S, Takii Y, Uzuka T, Takahashi H, Ito J, Tanaka R: Tentorial cavernous angioma with profuse bleeding. Case report. J Neurosurg Pediatr; 2009 Jan;3(1):37-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tentorial cavernous angioma with profuse bleeding. Case report.
  • This 15-year-old boy with a tentorial cavernous angioma reported occasional headache and scintillation in his left visual field.
  • A cavernous angioma of the tentorium was suspected based on this finding, and as expected from the radiological findings, profuse bleeding was encountered during tumor removal.
  • The histological diagnosis was a cavernous angioma.
  • A cavernous angioma of the tentorium is extremely rare but should be differentiated from a meningioma preoperatively given that a cavernous angioma of dural origin tends to bleed massively during removal.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / surgery. Infratentorial Neoplasms / surgery. Intracranial Hemorrhages / surgery. Supratentorial Neoplasms / surgery

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  • (PMID = 19119902.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. Yang HD, Lee KH: Medullary Hemorrhage after Ischemic Wallenberg's Syndrome in a Patient with Cavernous Angioma. J Clin Neurol; 2010 Dec;6(4):221-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Medullary Hemorrhage after Ischemic Wallenberg's Syndrome in a Patient with Cavernous Angioma.
  • BACKGROUND: The main complication of cerebral cavernous angioma is hemorrhage.
  • Ischemic stroke as a complication of cerebral cavernous angioma has rarely been described, and hemorrhage after ischemic Wallenberg's syndrome has not been reported before.
  • Follow-up magnetic resonance imaging revealed a cavernous angioma in the right medulla.
  • CONCLUSIONS: We presume that cerebral cavernous angioma was responsible for both the ischemia and the hemorrhage, and we also cautiously speculate that the aspirin contributed to the development of hemorrhage in the previously infarcted area.

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  • (PMID = 21264204.001).
  • [ISSN] 2005-5013
  • [Journal-full-title] Journal of clinical neurology (Seoul, Korea)
  • [ISO-abbreviation] J Clin Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC3024528
  • [Keywords] NOTNLM ; cavernous angioma / hemorrhage / ischemia / medulla oblongata
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60. Hanaya R, Arita K, Itoh Y, Kiura Y, Iida K, Kurisu K: Zygomatic osteotomy for resection of medial temporal cavernous angioma in dominant hemisphere after subdural grid electroencephalographic study. Hiroshima J Med Sci; 2006 Mar;55(1):39-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Zygomatic osteotomy for resection of medial temporal cavernous angioma in dominant hemisphere after subdural grid electroencephalographic study.
  • We report the treatment of a patient suffering from intractable epilepsy caused by a large cavernous angioma in the hippocampus of his dominant hemisphere.
  • However, total removal of a large cavernous angioma in the medial temporal structure of dominant hemisphere is occasionally difficult because of the depth of the lesion and its contiguity with eloquent brain structures.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / surgery. Subdural Space / pathology. Subdural Space / surgery. Zygoma / pathology. Zygoma / surgery

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  • (PMID = 16594552.001).
  • [ISSN] 0018-2052
  • [Journal-full-title] Hiroshima journal of medical sciences
  • [ISO-abbreviation] Hiroshima J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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61. Boockvar JA, Stiefel M, Malhotra N, Dolinskas C, Dwyer-Joyce C, LeRoux PD: Dural cavernous angioma of the posterior sagittal sinus: case report. Surg Neurol; 2005 Feb;63(2):178-81; discussion 181
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dural cavernous angioma of the posterior sagittal sinus: case report.
  • BACKGROUND: Extraaxial cavernous hemangiomas (cavernomas) are very rare lesions, and less than 20 descriptions of these lesions outside the middle fossa have been reported.
  • In this report, we describe a dural cavernous angioma involving the posterior sagittal sinus and discuss the clinical, radiological, operative, and histological features of this very uncommon lesion.
  • The histological features were consistent with cavernous angioma.
  • [MeSH-major] Cavernous Sinus / surgery. Dura Mater / surgery. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / surgery. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / surgery

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  • (PMID = 15680668.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Alves de Sousa A: [Deep-seated (corpus callosum, intraventricular, basal ganglia and insula) and brain stem cavernous angiomas. Experience in Brazil]. Neurochirurgie; 2007 Jun;53(2-3 Pt 2):182-91

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Deep-seated (corpus callosum, intraventricular, basal ganglia and insula) and brain stem cavernous angiomas. Experience in Brazil].
  • [MeSH-major] Basal Ganglia / pathology. Brain Stem / pathology. Central Nervous System Neoplasms / pathology. Cerebral Cortex / pathology. Cerebral Ventricles / pathology. Corpus Callosum / pathology. Hemangioma, Cavernous, Central Nervous System / pathology

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  • (PMID = 17507054.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 44
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63. Takebayashi S, Hashizume K, Uchida K, Tanaka T: [A case of coexistence with cavernous angioma and focal cortical dysplasia]. No To Shinkei; 2006 Mar;58(3):245-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of coexistence with cavernous angioma and focal cortical dysplasia].
  • We reported a case with seizures resulting from brain lesions which pathologically demonstrated a coexistence with a cavernous angioma and a focal cortical dysplasia.
  • We verified to be pathologically coexistent with a cavernous angioma and a focal cortical dysplasia.
  • [MeSH-major] Brain Neoplasms / complications. Cerebral Cortex / abnormalities. Hemangioma, Cavernous / complications

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  • (PMID = 16629451.001).
  • [ISSN] 0006-8969
  • [Journal-full-title] Nō to shinkei = Brain and nerve
  • [ISO-abbreviation] No To Shinkei
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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64. Sakakibara Y, Taguchi Y, Uchida K: [A case of cavernous angioma presenting as migrainous attack]. No Shinkei Geka; 2010 Mar;38(3):287-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of cavernous angioma presenting as migrainous attack].
  • Magnetic resonance imaging revealed a typical feature of cavernous angioma (CA) at the left temporooccipital lobe and electroencephalogram showed frequent spike waves at the same region.
  • [MeSH-major] Brain Neoplasms / complications. Hemangioma, Cavernous / complications. Migraine Disorders / etiology. Temporal Lobe

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  • (PMID = 20229775.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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65. González-Darder JM, Pesudo-Martinéz JV: [Facial nerve palsy due to cavernous angioma of the petrous bone. Case report]. Neurocirugia (Astur); 2007 Feb;18(1):44-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Facial nerve palsy due to cavernous angioma of the petrous bone. Case report].
  • [Transliterated title] Parálisis facial por angioma cavernoso del peñasco. Caso clínico.
  • The routine computed tomographic and magnetic resonance imaging studies showed no abnormalities, but the same imaging techniques done after the clinical suspiction identified a less that 1cm lesion that was compatible with an osseous cavernous angioma.
  • [MeSH-major] Bone Neoplasms / complications. Facial Nerve / physiopathology. Facial Paralysis / etiology. Hemangioma, Cavernous / complications. Nerve Compression Syndromes / etiology. Petrous Bone / blood supply

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  • (PMID = 17393046.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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66. Mrabet H, Bahri Ben Mrad F, Touibi S, Mrabet A: [Presentation of a cavernous angioma with an oculomotor nuclear syndrome: a case report]. Rev Neurol (Paris); 2006 Feb;162(2):238-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Presentation of a cavernous angioma with an oculomotor nuclear syndrome: a case report].
  • CONCLUSION: This neuro-ophthalmological complication of a cavernous angioma, as seen in our patient, has rarely been described in the literature.
  • [MeSH-major] Brain Stem Neoplasms / diagnosis. Hemangioma, Cavernous, Central Nervous System / diagnosis. Oculomotor Nerve Diseases / etiology

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  • (PMID = 16518266.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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67. Smith ER, Scott RM: Cavernous malformations. Neurosurg Clin N Am; 2010 Jul;21(3):483-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous malformations.
  • Cavernous malformations (CMs) are vascular lesions found in the central nervous system (CNS) and throughout the body and have been called cavernomas, cavernous angiomas, and cavernous hemangiomas.
  • [MeSH-major] Cerebral Arteries / abnormalities. Cerebral Arteries / surgery. Hemangioma, Cavernous, Central Nervous System / pathology. Hemangioma, Cavernous, Central Nervous System / surgery. Neurosurgical Procedures / methods. Neurosurgical Procedures / standards

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20561497.001).
  • [ISSN] 1558-1349
  • [Journal-full-title] Neurosurgery clinics of North America
  • [ISO-abbreviation] Neurosurg. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 62
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68. Ohta Y, Chong JM: [Solitary brain metastasis of thyroid papillary carcinoma mimicking a cavernous angioma by MRI]. No Shinkei Geka; 2009 May;37(5):467-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solitary brain metastasis of thyroid papillary carcinoma mimicking a cavernous angioma by MRI].
  • MRI showed a mixed intensity mass with a perifocal low intensity rim in T2WI, mimicking cavernous angioma.
  • The mass was presurgically diagnosed as a cavernous angioma but was actually a case of brain metastasis.
  • We must manage carefully a mass resembling cavemous angioma in MRI in consideration of the possibility of its being another diseases such as a metastatic tumor.
  • [MeSH-minor] Diagnosis, Differential. Hemangioma, Cavernous, Central Nervous System. Humans. Male. Middle Aged

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  • (PMID = 19432095.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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69. Nishijima H, Nishimura S, Furuno Y, Kaimori M, Nishijima M: [A case of posttraumatic forehead cavernous angioma]. No Shinkei Geka; 2009 Sep;37(9):899-904
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of posttraumatic forehead cavernous angioma].
  • Cavernous angiomas of the bone are rare tumors.
  • Most cavernous angiomas of the bone are congenital tumors.
  • In a review of the literature, we found only one case report of de novo generation of a skull cavernous angioma.
  • Pathological findings showed a cavernous angioma-like lesion with some atypical details.
  • We finally diagnosed the lesion as a de novo cavernous angioma.
  • [MeSH-major] Frontal Bone / injuries. Hemangioma, Cavernous / pathology. Skull Neoplasms / pathology

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  • (PMID = 19764425.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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70. Pino Rivero V, González Palomino A, Pantoja Hernández CG, Trinidad Ruíz G, Marqués Rebollo L, Blasco Huelva A: [Pontine cavernous angioma (cavernoma) with initial ENT manifestations]. An Otorrinolaringol Ibero Am; 2006;33(1):35-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pontine cavernous angioma (cavernoma) with initial ENT manifestations].
  • [Transliterated title] Angioma cavernoso del tronco cerebral (cavernoma) con manifestaciones orl iniciales.
  • Her audiometry showed an unilateral discreet sensorineural hipoacusia and the cranial IRM, a mass of 20 mm diameter in right pontine region and bulbus informed as cavernous angioma with signs of recent bleeding.
  • [MeSH-major] Central Nervous System Neoplasms / complications. Central Nervous System Neoplasms / pathology. Hearing Loss / diagnosis. Hearing Loss / etiology. Hemangioma, Cavernous, Central Nervous System / complications. Hemangioma, Cavernous, Central Nervous System / pathology. Pons / pathology

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  • (PMID = 16566194.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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71. Stavrinou LC, Stranjalis G, Flaskas T, Sakas DE: Trigonal cavernous angioma: a short illustrated review. Acta Neurochir (Wien); 2009 Nov;151(11):1517-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Trigonal cavernous angioma: a short illustrated review.
  • METHODS: We performed a search of the literature of the last 30 years and identified all cases of intraventricular cavernous angiomas.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Cerebral Ventricle Neoplasms / physiopathology. Hemangioma, Cavernous, Central Nervous System / pathology. Hemangioma, Cavernous, Central Nervous System / physiopathology. Lateral Ventricles / pathology

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  • (PMID = 19300903.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
  • [Number-of-references] 23
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72. Sürücü O, Sure U, Gaetzner S, Stahl S, Benes L, Bertalanffy H, Felbor U: Clinical impact of CCM mutation detection in familial cavernous angioma. Childs Nerv Syst; 2006 Nov;22(11):1461-4
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  • [Title] Clinical impact of CCM mutation detection in familial cavernous angioma.
  • INTRODUCTION AND BACKGROUND: A 3-year-old Bosnian girl with a large symptomatic brainstem and multiple supratentorial cavernous angiomas, who underwent neurosurgical treatment, is presented.
  • [MeSH-major] Brain Neoplasms / genetics. Family Health. Hemangioma, Cavernous / genetics. Microtubule-Associated Proteins / genetics. Mutation. Proto-Oncogene Proteins / genetics

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  • (PMID = 16983571.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / KRIT1 protein, human; 0 / Microtubule-Associated Proteins; 0 / Proto-Oncogene Proteins
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73. Yamamoto R, Nishiyama T, Kurokawa T, Hakii Y, Kishida H, Kuroiwa Y: [A case of cavernous angioma in the lower pons, showing subacute onset of unilateral cranial nerve palsy and segmental sensory disturbance]. Rinsho Shinkeigaku; 2009 Jan;49(1):32-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of cavernous angioma in the lower pons, showing subacute onset of unilateral cranial nerve palsy and segmental sensory disturbance].
  • He was found to have cavernous angioma in the lower pons.
  • He was diagnosed as having hemorrhage originating from a cavernous angioma.
  • [MeSH-major] Brain Stem Neoplasms / complications. Cranial Nerve Diseases / etiology. Facial Nerve Diseases / etiology. Hemangioma, Cavernous / complications

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  • (PMID = 19227894.001).
  • [ISSN] 0009-918X
  • [Journal-full-title] Rinshō shinkeigaku = Clinical neurology
  • [ISO-abbreviation] Rinsho Shinkeigaku
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 10
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74. Cotton CA, Beall DP, Winter BJ, Fortman BJ, Kirby AB, Ly JQ: Cavernous angioma of the cerebellopontine angle. Curr Probl Diagn Radiol; 2006 May-Jun;35(3):120-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous angioma of the cerebellopontine angle.
  • Although cavernous hemangiomas are commonly found supratentorially, their presence in the internal auditory canal is uncommon.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Cerebellopontine Angle / pathology. Hemangioma, Cavernous / diagnosis. Neurilemmoma / diagnosis

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  • (PMID = 16701123.001).
  • [ISSN] 0363-0188
  • [Journal-full-title] Current problems in diagnostic radiology
  • [ISO-abbreviation] Curr Probl Diagn Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Iglesias S, Ayerbe J, Sarasa JL, Sousa P, Torres C, Ruiz-Barnés P: [Dumbbell-shaped spinal epidural cavernous angioma. Case report and review of the literature]. Neurocirugia (Astur); 2008 Jun;19(3):248-53
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  • [Title] [Dumbbell-shaped spinal epidural cavernous angioma. Case report and review of the literature].
  • Spinal epidural cavernous angiomas are rare vascular malformations that exceptionally present with dumbbell-shape morphology.
  • [MeSH-major] Epidural Neoplasms / diagnosis. Epidural Neoplasms / pathology. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / pathology. Spine / pathology

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  • (PMID = 18654724.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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76. Baheti AD, Mahore AS, Zade BP, Jalali R: Meningioma and cavernous angioma following childhood radiotherapy. J Cancer Res Ther; 2010 Jul-Sep;6(3):333-5
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  • [Title] Meningioma and cavernous angioma following childhood radiotherapy.
  • We report a rare case of development of both a meningioma and a cavernous angioma following prophylactic cranial irradiation as a part of treatment of ALL.

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  • (PMID = 21119268.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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77. Obermann M, Gizewski ER, Felsberg J, Maschke M: Cavernous malformation with hemorrhage of the conus medullaris and progressive sensory loss. Clin Neuropathol; 2006 Mar-Apr;25(2):95-7
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  • [Title] Cavernous malformation with hemorrhage of the conus medullaris and progressive sensory loss.
  • Numerous studies have shown that cavernous malformations may be localized in almost every region of the brain as well as in the spinal cord.
  • Spinal cord cavernous malformations (SCCM) have been diagnosed more frequently since magnetic resonance imaging (MRI) has become more widely available.
  • Spinal MRI showed a central, slightly lateralized intramedullary lesion 1 cm in diameter located within the conus medullaris that was suspicious for an intramedullary cavernous malformation.
  • The lesion was accompanied by a perifocal edema and showed an inhomogeneous hypointense core on T2WI consistent with an acute cavernous hemorrhage.
  • Treatment of symptomatic intramedullary cavernous angiomas should, if possible, consist of total surgical excision.
  • [MeSH-major] Hemangioma, Cavernous / pathology. Hemorrhage / pathology. Sensation Disorders / etiology. Spinal Cord Neoplasms / pathology

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  • (PMID = 16550743.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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78. Sade B, Lee DK, Prayson RA, Hughes GB, Lee JH: Intraosseous cavernous angioma of the petrous bone. Skull Base; 2009 May;19(3):237-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraosseous cavernous angioma of the petrous bone.
  • OBJECTIVE: Intraosseous cavernous angioma (CA) of the petrous bone is rare and preoperative diagnosis can be challenging, especially when its epicenter is outside the internal auditory canal (IAC) or geniculate ganglion.

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  • [Cites] AJNR Am J Neuroradiol. 1991 Nov-Dec;12(6):1193-4 [1763750.001]
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  • (PMID = 19881905.001).
  • [ISSN] 1532-0065
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2702196
  • [Keywords] NOTNLM ; Angioma / cavernous / hemangioma / internal auditory canal / intraosseous / petrous
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79. Maciunas JA, Syed TU, Cohen ML, Werz MA, Maciunas RJ, Koubeissi MZ: Triple pathology in epilepsy: coexistence of cavernous angiomas and cortical dysplasias with other lesions. Epilepsy Res; 2010 Sep;91(1):106-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Triple pathology in epilepsy: coexistence of cavernous angiomas and cortical dysplasias with other lesions.
  • In addition, each of these patients had a third form of a potentially epileptogenic lesion: hippocampal sclerosis in one, and venous angioma in the other.
  • [MeSH-major] Brain Neoplasms / pathology. Epilepsy / pathology. Hemangioma, Cavernous / pathology. Malformations of Cortical Development / pathology

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20674276.001).
  • [ISSN] 1872-6844
  • [Journal-full-title] Epilepsy research
  • [ISO-abbreviation] Epilepsy Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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80. Gianfrancesco F, Cannella M, Martino T, Maglione V, Esposito T, Innocenzi G, Vitale E, Liquori CL, Marchuk DA, Squitieri F: Highly variable penetrance in subjects affected with cavernous cerebral angiomas (CCM) carrying novel CCM1 and CCM2 mutations. Am J Med Genet B Neuropsychiatr Genet; 2007 Jul 5;144B(5):691-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Highly variable penetrance in subjects affected with cavernous cerebral angiomas (CCM) carrying novel CCM1 and CCM2 mutations.
  • Cavernous vascular malformations may affect brain and out-of-brain tissues.
  • In most cases, cerebral cavernous malformations (CCMs) involve the brain alone, and are rarely associated with skin hemangiomas, spinal cord, retinal, hepatic or vertebral lesions.
  • We found a novel CCM1 gene mutation (Q66X) in a family with apparently asymptomatic old-aged mutation carriers and patients who either had skin angiomas alone or the full association of cerebral, spinal, and skin lesions.
  • [MeSH-major] Carrier Proteins / genetics. Hemangioma, Cavernous, Central Nervous System / genetics. Microtubule-Associated Proteins / genetics. Mutation. Penetrance. Proto-Oncogene Proteins / genetics

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  • (PMID = 17440989.001).
  • [ISSN] 1552-4841
  • [Journal-full-title] American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
  • [ISO-abbreviation] Am. J. Med. Genet. B Neuropsychiatr. Genet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CCM2 protein, human; 0 / Carrier Proteins; 0 / KRIT1 protein, human; 0 / Microtubule-Associated Proteins; 0 / Proto-Oncogene Proteins
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81. Paolini S, Morace R, Di Gennaro G, Picardi A, Grammaldo LG, Meldolesi GN, Quarato PP, Raco A, Esposito V: Drug-resistant temporal lobe epilepsy due to cavernous malformations. Neurosurg Focus; 2006;21(1):e8
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  • [Title] Drug-resistant temporal lobe epilepsy due to cavernous malformations.
  • OBJECT: Supratentorial cavernous angiomas may be associated with drug-resistant focal epilepsy.
  • In this paper the authors focus on the preoperative workup and the surgical management of the disease in eight consecutive patients undergoing surgery for drug-resistant temporal lobe epilepsy (TLE) due to cavernous malformations (CMs), and the relevant literature on this issue is also reviewed.
  • [MeSH-major] Brain Neoplasms / complications. Brain Neoplasms / surgery. Epilepsy, Temporal Lobe / etiology. Epilepsy, Temporal Lobe / therapy. Hemangioma, Cavernous, Central Nervous System / complications. Hemangioma, Cavernous, Central Nervous System / surgery

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  • (PMID = 16859261.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants
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82. Summa A, Cerasti D, Crisi G, Ventura E, Ormitti F: Formation of intracerebral cavernous malformation after radiation treatment for medulloblastoma in a child. Neuroradiol J; 2009 May 15;22(2):198-203

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Formation of intracerebral cavernous malformation after radiation treatment for medulloblastoma in a child.
  • Cavernous malformations (CMs) are one of the four major types of vascular malformations of the central nervous system (CNS).
  • Literature reports also term them cavernomas, cavernous angiomas, angiographically occult vascular malformations and cavernous hemangiomas.CMs are composed of well-circumscribed vascular channels containing blood at various stages of evolution and show a low-flow vascular pattern.
  • They have usually been considered developmental lesions of the intracranial vasculature, but recently the de novo appearance of these malformations has been observed with increasing frequency.We describe a case of sporadic de novo formation of a CNS cavernous malformation following radiation treatment in a child with medulloblastoma.

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  • (PMID = 24207041.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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83. Son DW, Lee SW, Choi CH: Giant cavernous malformation : a case report and review of the literature. J Korean Neurosurg Soc; 2008 Apr;43(4):198-200

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant cavernous malformation : a case report and review of the literature.
  • Giant cavernous malformations (GCMs) occur very rarely and little has been reported about their clinical characteristics.
  • These fingings suggested a diagnosis of GCM accompanying venous angioma.
  • GCMs do not seem differ clinically, surgically or histopathologically from small cavernous angiomas, but imaging appearance of GCMs may be variable.

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  • (PMID = 19096644.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588260
  • [Keywords] NOTNLM ; Cavernous hemangioma / Seizure / Venous angioma
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84. González-Darder JM, Pesudo-Martínez JV, Merino-Peña J: [Trigonal cavernous angioma: case report]. Neurocirugia (Astur); 2007 Aug;18(4):330-2
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  • [Title] [Trigonal cavernous angioma: case report].
  • [Transliterated title] Angioma cavernoso del trígono ventricular. Caso clínico.
  • The authors report on an intraventricular cavernous angioma located at the right trigone in a 25-year-old male patient presented with a predominantly intralesional haemorrhage.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Hemangioma, Cavernous / pathology

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  • (PMID = 17882341.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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85. Acciarri N, Galassi E, Giulioni M, Pozzati E, Grasso V, Palandri G, Badaloni F, Zucchelli M, Calbucci F: Cavernous malformations of the central nervous system in the pediatric age group. Pediatr Neurosurg; 2009;45(2):81-104

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous malformations of the central nervous system in the pediatric age group.
  • OBJECTIVE: The main clinico-diagnostic features, risk factors and associated diseases of cavernous malformations (CMs), also called cavernous angiomas or cavernomas, of the central nervous system (CNS) in children are described, and the most relevant differences compared to the affected adult population are pointed out, focusing on the management of pediatric patients harboring cranial and spinal CMs.
  • [MeSH-major] Central Nervous System Neoplasms / diagnosis. Central Nervous System Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / diagnosis. Hemangioma, Cavernous, Central Nervous System / surgery

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  • [Copyright] Copyright (c) 2009 S. Karger AG, Basel.
  • (PMID = 19307743.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Switzerland
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86. Kamiyama H, Nishimura S, Kaimori M, Watanabe M, Furuno Y, Saito A, Nishijima M: Cavernous angioma associated with arteriovenous malformation of the brain--case report. Neurol Med Chir (Tokyo); 2010;50(2):131-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous angioma associated with arteriovenous malformation of the brain--case report.
  • A 61-year-old man presented a rare case of cerebral cavernous angioma associated with cerebral arteriovenous malformation (AVM) manifesting as headache.
  • Magnetic resonance imaging showed an AVM in the right occipital lobe and a cavernous angioma in the left middle fossa.
  • The histological diagnoses were cavernous angioma and AVM, respectively.
  • [MeSH-major] Brain Neoplasms / pathology. Hemangioma, Cavernous, Central Nervous System / pathology. Intracranial Arteriovenous Malformations / pathology. Sella Turcica / pathology. Skull Base Neoplasms / pathology

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  • (PMID = 20185878.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Angiogenic Proteins; 0 / Biomarkers, Tumor
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87. Ryan D: Cavernous malformations. J Neurosci Nurs; 2010 Oct;42(5):294-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous malformations.
  • Cavernous malformations (CMs) are a subset of neurovascular malformations, which include arteriovenous malformations (AVMs), venous malformations, and capillary telangiectasias.
  • CMs are referred to by many names, which may contribute to their being mistaken for malignant entities such as angiomas or hemangiomas.

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  • (PMID = 20968226.001).
  • [ISSN] 0888-0395
  • [Journal-full-title] The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
  • [ISO-abbreviation] J Neurosci Nurs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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88. Klein O, Freppel S, Auque J, Civit T: Cavernous angioma within an olfactory groove meningioma. Case report. J Neurosurg; 2006 Feb;104(2):325-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous angioma within an olfactory groove meningioma. Case report.
  • [MeSH-major] Hemangioma, Cavernous, Central Nervous System / pathology. Meningeal Neoplasms / complications. Meningioma / complications. Subarachnoid Hemorrhage / etiology

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  • (PMID = 16509509.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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89. Aladdin Y, Gross DW: Refractory status epilepticus during pregnancy secondary to cavernous angioma. Epilepsia; 2008 Sep;49(9):1627-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Refractory status epilepticus during pregnancy secondary to cavernous angioma.
  • SUMMARY: First-time seizure and status epilepticus during pregnancy have been previously reported as the initial manifestation of intracranial cavernous hemangioma.
  • Cranial MRI revealed a right frontal cavernous hemangioma.
  • [MeSH-major] Brain Neoplasms / complications. Hemangioma, Cavernous / complications. Phenytoin / therapeutic use. Status Epilepticus / diagnosis. Status Epilepticus / etiology


90. Ebrahimi A, Etemadifar M, Ardestani PM, Maghzi AH, Jaffe S, Nejadnik H: Cavernous angioma: a clinical study of 35 cases with review of the literature. Neurol Res; 2009 Oct;31(8):785-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous angioma: a clinical study of 35 cases with review of the literature.
  • BACKGROUND: Cavernous angioma is a vascular malformation which can be found in any region within the central nervous system.
  • OBJECTIVES: There are few clinical and demographic cavernous angioma studies with large sample sizes.
  • Therefore, the present study was designed to provide further information on the clinical and demographic characteristics of cavernous angioma using a relatively large sample of Persian patients.
  • METHODS: Patients with cavernous angioma were recruited from the outpatient neurology clinics in Isfahan, Iran, from October 2003 to October 2006.
  • RESULTS: In all cases, the diagnosis of cavernous angioma was based on brain magnetic resonance imaging.
  • There were 35 patients (female/male: 17 : 18) identified with cavernous angioma.
  • Moreover, our data demonstrated that if there is a history of cavernous angioma with intracranial hemorrhage in family members, the presenting cavernous angioma patient is more prone to intracranial hemorrhage.
  • [MeSH-major] Hemangioma, Cavernous

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  • (PMID = 19723446.001).
  • [ISSN] 0161-6412
  • [Journal-full-title] Neurological research
  • [ISO-abbreviation] Neurol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 134
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91. Corapçioğlu F, Akansel G, Gönüllü E, Yildiz K, Etuş V: Fatal giant pediatric intracranial cavernous angioma. Turk J Pediatr; 2006 Jan-Mar;48(1):89-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fatal giant pediatric intracranial cavernous angioma.
  • Cavernous angioma is a benign vascular lesion that may occur in the central nervous system.
  • A cavernous hemangioma was diagnosed with pathologic examination.
  • In conclusion, a cavernous angioma may occasionally follow a rapid and fatal course by causing gross hemorrhage in the pediatric age group.
  • [MeSH-major] Brain Neoplasms / diagnosis. Hemangioma, Cavernous / diagnosis

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  • (PMID = 16562795.001).
  • [ISSN] 0041-4301
  • [Journal-full-title] The Turkish journal of pediatrics
  • [ISO-abbreviation] Turk. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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92. Gutiérrez-González R, Casanova-Peño I, Porta-Etessam J, Martínez A, Boto GR: Dural cavernous haemangioma of the anterior cranial fossa. J Clin Neurosci; 2010 Jul;17(7):936-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dural cavernous haemangioma of the anterior cranial fossa.
  • Extra-axial cavernous haem angiomas are uncommon lesions histologically identical to cavernomas in other locations.
  • We describe a patient suffering from loss of the sense of smell, due to a cavernous haemangioma implanted in the dura mater of the anterior cranial fossa close to the olfactory bulb.
  • [MeSH-major] Cranial Fossa, Anterior / radiography. Dura Mater / radiography. Hemangioma, Cavernous, Central Nervous System / radiography. Meningeal Neoplasms / radiography

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  • (PMID = 20400315.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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93. Sakakibara Y, Matsumori T, Taguchi Y, Koizumi H: Supratentorial high convexity intradural extramedullary cavernous angioma: case report. Neurol Med Chir (Tokyo); 2010;50(4):328-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Supratentorial high convexity intradural extramedullary cavernous angioma: case report.
  • Histological examination revealed the typical findings of cavernous angioma.
  • Cavernous angioma should be considered in the differential diagnosis of supratentorial high convexity intradural extramedullary tumor, especially appearing as a heterogeneously enhanced mass adjacent to the brain parenchyma causing mass effect.
  • [MeSH-major] Hemangioma, Cavernous, Central Nervous System / pathology. Supratentorial Neoplasms / pathology

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  • (PMID = 20448428.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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94. Che XM, Xu QW, Shou JJ, Gu SX, Zhang MG, Sun B, Cui DM: [The diagnosis and surgical management for intramedullary spinal cord cavernous angioma]. Zhonghua Yi Xue Za Zhi; 2008 May 20;88(19):1306-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The diagnosis and surgical management for intramedullary spinal cord cavernous angioma].
  • OBJECTIVE: The clinical diagnosis and surgical management of intramedullary spinal cord cavernous angioma were discussed.
  • METHOD: Total 19 patients with intramedullary cavernous angioma were analyzed retrospectively on the clinical manifestation, radiographic feature, diagnosis and differentiation, surgical technique and caution.
  • RESULT: All the 19 patients pathologically diagnosed with spinal cord cavernous angioma got good surgical results, besides one patient showed loss of proprioception.
  • CONCLUSION: The clinical symptom of most of the patients with spinal cord cavernous angioma presented mildly at onset, but deteriorated gradually because of repeated prehemorrhage.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / surgery. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / surgery

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  • (PMID = 18956697.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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95. Idiaquez J, Araya P, Benarroch E: Orthostatic hypotension associated with dorsal medullary cavernous angioma. Acta Neurol Scand; 2009 Jan;119(1):45-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orthostatic hypotension associated with dorsal medullary cavernous angioma.
  • METHOD: A case with dorsal medullary cavernous angioma presenting with OH is described.
  • RESULTS: The patient had marked OH after partial removal of the cavernous angioma.
  • [MeSH-major] Brain Stem Neoplasms / diagnosis. Fludrocortisone / therapeutic use. Hemangioma, Cavernous / diagnosis. Hypotension, Orthostatic / etiology. Midodrine / therapeutic use

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  • (PMID = 18549416.001).
  • [ISSN] 1600-0404
  • [Journal-full-title] Acta neurologica Scandinavica
  • [ISO-abbreviation] Acta Neurol. Scand.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Adrenergic alpha-Agonists; 0 / Anti-Inflammatory Agents; 6YE7PBM15H / Midodrine; U0476M545B / Fludrocortisone
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96. Matsuno A, Nagashima T, Tajima Y, Sugano I: A diagnostic pitfall: Angiosarcoma of the brain mimicking cavernous angioma. J Clin Neurosci; 2005 Aug;12(6):688-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A diagnostic pitfall: Angiosarcoma of the brain mimicking cavernous angioma.
  • We present a rare case of cerebral angiosarcoma, which comprised both poorly-differentiated solid areas and well-differentiated areas that led to the misdiagnosis of cavernous angioma.
  • A 79-year old woman presented with an intracerebral hematoma in the left frontal lobe that was misdiagnosed as a hemorrhage from a cavernous angioma at initial operation.
  • Angiosarcoma may have areas with different degrees of differentiation and when a cavernous angioma is suspected histopathologically, the specimen should also be carefully explored for poorly-differentiated areas and the diagnosis of primary or secondary angiosarcoma considered.
  • [MeSH-major] Brain Neoplasms / diagnosis. Hemangioma, Cavernous / diagnosis. Hemangiosarcoma / diagnosis

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  • (PMID = 16023347.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Scotland
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97. Caroli E, Acqui M, Trasimeni G, Di Stefano D, Ferrante L: A case of intraroot cauda equina cavernous angioma: clinical considerations. Spinal Cord; 2007 Apr;45(4):318-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of intraroot cauda equina cavernous angioma: clinical considerations.
  • CONCLUSION: Lumbar intradural cavernous angioma may present with sciatalgia, low-back pain, neurological deficit, or, more rarely with subarachnoid hemorrhage or hydrocephalus.
  • Sometimes the sacrifice of the spinal root is inevitable because, as in present case, the cavernous angioma is included in the nerve root.
  • [MeSH-major] Cauda Equina / pathology. Hemangioma, Cavernous / diagnosis. Magnetic Resonance Imaging / methods. Spinal Cord Neoplasms / diagnosis

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  • (PMID = 16896337.001).
  • [ISSN] 1362-4393
  • [Journal-full-title] Spinal cord
  • [ISO-abbreviation] Spinal Cord
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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98. Saito A, Suzuki Y, Furuno Y, Kamiyama H, Nishimura S, Kaimori M, Nishijima M: Gradual deterioration of brainstem cavernous angioma associated with hemophilia--case report. Neurol Med Chir (Tokyo); 2008 Sep;48(9):394-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gradual deterioration of brainstem cavernous angioma associated with hemophilia--case report.
  • A 49-year-old man presented with a brainstem cavernous angioma associated with hemophilia manifesting as gradual progression of neurological deficits over a period of 2 weeks.
  • The histological diagnosis was cavernous angioma.
  • Surgery can be effective for the treatment of hemorrhagic cavernous angioma associated with hemophilia after initiation of supplementary therapy with coagulation factor.
  • [MeSH-major] Brain Stem / blood supply. Factor IX / therapeutic use. Hemangioma, Cavernous, Central Nervous System / complications. Hemophilia B / complications. Intracranial Hemorrhages / etiology

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  • (PMID = 18812681.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 9001-28-9 / Factor IX
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99. Ozer E, Kalemci O, Yücesoy K, Canda S: Optochiasmatic cavernous angioma: unexpected diagnosis. Case report. Neurol Med Chir (Tokyo); 2007 Mar;47(3):128-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optochiasmatic cavernous angioma: unexpected diagnosis. Case report.
  • A 15-year-old boy presented with an extremely rare optochiasmatic cavernous angioma.
  • Repeat magnetic resonance imaging showed optochiasmatic cavernous angioma which had doubled in size.
  • Optochiasmatic cavernous malformation should be treated by surgical excision, whereas biopsy is useless and may result in enlargement.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Optic Chiasm. Optic Nerve Neoplasms / diagnosis

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  • (PMID = 17384496.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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100. Sato K, Oka H, Utsuki S, Shimizu S, Suzuki S, Fujii K: Neuroendoscopic appearance of an intraventricular cavernous angioma blocking the foramen of monro - case report. Neurol Med Chir (Tokyo); 2006 Nov;46(11):548-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neuroendoscopic appearance of an intraventricular cavernous angioma blocking the foramen of monro - case report.
  • The diagnosis was intraventricular cavernous angioma.
  • When the neuroendoscope touched the angioma, the wall collapsed and bled.
  • Endoscopic removal of the angioma was abandoned, and craniotomy and resection of the angioma were performed.
  • Preoperative diagnosis of intraventricular cavernous angioma is difficult based on neuroimaging.
  • [MeSH-major] Cerebral Ventricles / pathology. Endoscopy / methods. Hemangioma, Cavernous, Central Nervous System / diagnosis. Hydrocephalus / diagnosis. Hydrocephalus / etiology. Lateral Ventricles / pathology

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  • (PMID = 17124371.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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