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1. Gołabek W, Szymańska A, Siwiec H, Trojanowski P: [Transpalatal approach for juvenile angiofibroma]. Otolaryngol Pol; 2008;62(1):16-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Transpalatal approach for juvenile angiofibroma].
  • INTRODUCTION: Juvenile nasopharyngeal angiofibromas (JNA) are highly vascular, locally invasive tumours which originate in the sphenopalatine foramen.
  • The aim of this study was to evaluate the transpalatal approach for juvenile angiofibroma.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 18637415.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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2. Janaki MG, Nirmala S, Rajeev AG: Nasopharyngeal angiofibroma treated with radiotherapy. J Cancer Res Ther; 2007 Apr-Jun;3(2):100-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasopharyngeal angiofibroma treated with radiotherapy.
  • Nasopharyngeal angiofibroma is a rare, highly vascular, benign, locally aggressive tumor, affecting boys of adolescent age.
  • Although surgery is the treatment of choice in early cases, considerable debate exists regarding the treatment of advanced disease with intracranial extension.
  • We are herewith reporting a case of nasopharyngeal angiofibroma who showed complete hemostasis and improvement in vision to radiotherapy.
  • [MeSH-major] Angiofibroma / radiotherapy. Nasopharyngeal Neoplasms / radiotherapy

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  • (PMID = 17998732.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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3. Rosón E, Flórez A, Feal C, De La Torre C, García-Doval I, Abalde T, Cruces M: Progressive nodular histiocytoma associated with thrombocytopenia with absent radii (TAR syndrome) and angiofibromas. Acta Derm Venereol; 2006;86(4):348-50
MedlinePlus Health Information. consumer health - Skin Conditions.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Progressive nodular histiocytoma associated with thrombocytopenia with absent radii (TAR syndrome) and angiofibromas.
  • Moreover, the patient had numerous smooth erythematous papules on her chin and around her nose, which were diagnosed histologically as angiofibromas.
  • To our knowledge progressive nodular histiocytoma has not been reported previously associated either with TAR syndrome or with angiofibromas.
  • [MeSH-major] Angiofibroma / complications. Ectromelia / complications. Histiocytoma / pathology. Radius / abnormalities. Skin Diseases / pathology. Thrombocytopenia / complications

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  • (PMID = 16874423.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Databank-accession-numbers] OMIM/ 274000
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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4. Łukomski M, Danilewicz M, Pajor A: [Juvenile angiofibroma in adults]. Otolaryngol Pol; 2008;62(1):20-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile angiofibroma in adults].
  • INTRODUCTION: Juvenile nasopharyngeal angiofibroma is a benign lesion which is characterized by three distinctive features: it occurs only in one sex, one period of age and in one location in the organism.
  • MATERIAL AND METHOD: Basing on literature and our series concerning 36 patients treated during 50 years, we present atypical cases of angiofibroma.
  • Our study reports three cases of angiofibroma, two of them concerning males aged 34 and 49 years and one case - female aged 68 years.
  • Results of histological examination of our atypical cases were similar as in angiofibromas observed in adolescents.
  • CONCLUSION: Our study concerning the occurrence of juvenile angiofibroma in adults, also in female, as the other observations from literature may constitute some remarks in discussion about the pathogenesis and clinics of this tumor.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 18637416.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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5. Schick B, Wemmert S, Jung V, Steudel WI, Montenarh M, Urbschat S: Genetic heterogeneity of the MYC oncogene in advanced juvenile angiofibromas. Cancer Genet Cytogenet; 2006 Jan 1;164(1):25-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic heterogeneity of the MYC oncogene in advanced juvenile angiofibromas.
  • Despite their benign histological appearance, juvenile angiofibromas sometimes exhibit an aggressive growth behavior.
  • Because intensive cross-talk among beta-catenin, androgen receptor, and C-MYC has been detected recently, we analyzed expression of the C-MYC protooncogene (MYC) on the genetic, transcriptional and translational level in seven sporadic juvenile angiofibromas.
  • Two-color in situ hybridization analyses for chromosome 8 and MYC found in all seven juvenile angiofibromas significant MYC losses.
  • In the three advanced juvenile angiofibromas of this series (Fisch stages III and IV) additional significant MYC gains were observed demonstrating a genetic heterogeneity for the MYC protooncogene.
  • Semiquantitative RT-PCR analyses from laser microdissected endothelial cells and fibroblasts found no differences of C-MYC mRNA levels, leaving open the question of the neoplastic cell in juvenile angiofibromas.
  • The finding of genetic MYC heterogeneity associated with C-MYC overexpression on the mRNA and protein level in advanced juvenile angiofibromas indicates involvement of the MYC oncogene in aggressive growth behavior.
  • [MeSH-major] Angiofibroma / genetics. Genes, myc. Genetic Heterogeneity

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  • (PMID = 16364759.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins c-myc; 0 / RNA, Messenger; 0 / Receptors, Androgen; 0 / Transforming Growth Factor beta; 0 / beta Catenin
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6. Fonseca AS, Vinhaes E, Boaventura V, Andrade NA, Dias LA, Medeiros V, Coifman F: Surgical treatment of non-embolized patients with nasoangiofibroma. Braz J Otorhinolaryngol; 2008 Jul-Aug;74(4):583-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Juvenile nasopharyngeal angiofibroma (JNA) is an uncommon tumor of the sphenopalatine foramen.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18852986.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Brazil
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7. Liu JT, Briner RP, Friedman JA: Comparison of inpatient vs. outpatient anterior cervical discectomy and fusion: a retrospective case series. BMC Surg; 2009;9:3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: All patients undergoing single-level anterior cervical discectomy and fusion with plating between August 2005 and May 2007 by two surgeons (RPB or JAF) were retrospectively reviewed.

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  • (PMID = 19265540.001).
  • [ISSN] 1471-2482
  • [Journal-full-title] BMC surgery
  • [ISO-abbreviation] BMC Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2657115
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8. Amin AA: Maxillary swing approach for surgical resection of recurrent nasopharyngeal tumors. J Egypt Natl Canc Inst; 2007 Sep;19(3):219-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The nasopharynx, para-pharyngeal space and infratemporal fossa are now exposed facilitating complete resection of the tumor.
  • Three patients had recurrent carcinoma of the nasopharynx after primary radiation therapy, while four patients had locally advanced recurrent juvenile nasopharyngeal angiofibroma (JNA).
  • The follow-up period ranged from 3 months to 6 years, one patient died from distant disease and another patient is alive with residual intra-cranial disease.
  • The maxillary swing approach allows safe and complete resection for nasopharyngeal carcinoma as well as juvenile angiofibroma with intracranial extension.
  • Key Words : Recurrent nasopharyngeal tumors -Salvage nasopharyngectomy -Juvenile nasopharyngeal angiofibroma.

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  • (PMID = 19190695.001).
  • [ISSN] 1110-0362
  • [Journal-full-title] Journal of the Egyptian National Cancer Institute
  • [ISO-abbreviation] J Egypt Natl Canc Inst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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9. Schick B, Veldung B, Wemmert S, Jung V, Montenarh M, Meese E, Urbschat S: p53 and Her-2/neu in juvenile angiofibromas. Oncol Rep; 2005 Mar;13(3):453-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p53 and Her-2/neu in juvenile angiofibromas.
  • The pathogenesis of juvenile angiofibroma (JA) remains unsolved.
  • [MeSH-major] Angiofibroma / genetics. Angiofibroma / physiopathology. Chromosomes, Human, Pair 17. Gene Expression Profiling. Receptor, ErbB-2 / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis

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  • (PMID = 15706416.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / Tumor Suppressor Protein p53; EC 2.7.10.1 / Receptor, ErbB-2
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10. Szymańska A, Gołabek W, Siwiec H, Pietura R, Szczerbo-Trojanowska M: [Juvenile angiofibroma: the value of CT and MRI for treatment planning and follow-up]. Otolaryngol Pol; 2005;59(1):85-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile angiofibroma: the value of CT and MRI for treatment planning and follow-up].
  • Juvenile angiofibroma is a rare, benign, hypervascular, nasopharyngeal tumour.
  • There were 40 patients with juvenile angiofibroma.
  • [MeSH-major] Angiofibroma / diagnosis. Magnetic Resonance Angiography. Nasopharyngeal Neoplasms / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 15915924.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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11. Starlinger V, Wendler O, Gramann M, Schick B: Laminin expression in juvenile angiofibroma indicates vessel's early developmental stage. Acta Otolaryngol; 2007 Dec;127(12):1310-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laminin expression in juvenile angiofibroma indicates vessel's early developmental stage.
  • CONCLUSION: This study confirms the wide range of vascular architecture in juvenile angiofibromas.
  • Proof of laminin alpha2 expression in tumour vessels is suggested to indicate presence of vessels of early developmental stage in juvenile angiofibromas, supporting the concept that plexus remnants of the first branchial arch artery contribute to the vascular tumour component.
  • The goal of this study was to analyse the expression of laminins in juvenile angiofibromas.
  • MATERIALS AND METHODS: A detailed analysis of the laminin isoform expression was performed by immunofluorescence staining for laminin chains alpha1, alpha2, alpha3, alpha4, alpha5, beta1, beta2, beta3, gamma1, gamma2, and gamma3 on cryosections of 10 juvenile angiofibromas and inferior nasal turbinate tissue for control.
  • RESULTS: Vascular staining of the different laminin chains revealed areas of differential vessel density in juvenile angiofibromas and irregularities in vessel size, configuration and architecture.
  • Similar to vessels in nasal turbinates, laminins alpha4, alpha5, beta1, beta2 and gamma1 were found to be expressed in juvenile angiofibroma vessels.
  • In contrast to vessels of nasal turbinates, staining for alpha2 and alpha3 chains was only detected in vessels of juvenile angiofibromas.
  • [MeSH-major] Angiofibroma / pathology. Basement Membrane / metabolism. Laminin / metabolism. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 17851944.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Laminin
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12. Thornton M, Mahesh BN, Lang J: Endoscopic resection of a juvenile angiofibroma: the role of the XPS microdebrider. J Laparoendosc Adv Surg Tech A; 2005 Apr;15(2):194-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic resection of a juvenile angiofibroma: the role of the XPS microdebrider.
  • Juvenile angiofibromas are vascular tumors found almost exclusively in the adolescent male.
  • Although benign, their clinical course can be aggressive and can result in major morbidity and mortality.
  • Endoscopic transnasal resection of juvenile angiofibromas, confined to the nose, paranasal sinuses, pterygopalatine fossa, and medial infratemporal fossa, has been a significant advance in their management, eliminating or reducing the need for extensive soft tissue and bony dissection of traditional surgical approaches.
  • We discuss a case of a juvenile angiofibroma resected transnasally using the XPS microdebrider (Medtonic Xomed, Jacksonville, Florida) and outline the role of this instrument in this surgery.
  • [MeSH-major] Angiofibroma / surgery. Debridement / instrumentation. Endoscopy / methods. Head and Neck Neoplasms / surgery

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  • (PMID = 15898917.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Belmar P, Boixeda P, Baniandrés O, Fernández-Lorente M, Arrazola JM: [Long-term follow up of angiofibromas treated with CO2 laser in 23 patients with tuberous sclerosis]. Actas Dermosifiliogr; 2005 Oct;96(8):498-503
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Long-term follow up of angiofibromas treated with CO2 laser in 23 patients with tuberous sclerosis].
  • [Transliterated title] Seguimiento a largo plazo de angiofibromas tratados con láser de CO2 en 23 pacientes con esclerosis tuberosa.
  • INTRODUCTION: Tuberous sclerosis is an autosomal dominant disease in which hamartomas form in multiple organs.
  • Cutaneous changes are one of the primary characteristics of this disease.
  • These include angiofibromas (AF), a common form of presentation that causes significant cosmetic and medical problems.
  • The aim of our study is to assess the long-term response of the treatment of angiofibromas.
  • METHODS: A retrospective study was carried out on 23 patients with angiofibromas treated with CO2 laser.
  • We classified the angiofibromas by size, initial treatment results and patients' ages (< 20 years and 20 years or older).
  • After treatment, patients were followed up for a period of six months to 10 years.
  • When we analyzed the long-term results by the size of the angiofibromas, initial result and patients' ages, we found no statistically significant differences among the different groups.
  • [MeSH-major] Angiofibroma / complications. Angiofibroma / surgery. Laser Therapy. Skin Neoplasms / complications. Skin Neoplasms / surgery. Tuberous Sclerosis / complications

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  • (PMID = 16476284.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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14. El-Banhawy OA, Ragab A, El-Sharnoby MM: Surgical resection of type III juvenile angiofibroma without preoperative embolization. Int J Pediatr Otorhinolaryngol; 2006 Oct;70(10):1715-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical resection of type III juvenile angiofibroma without preoperative embolization.
  • OBJECTIVES/HYPOTHESIS: To evaluate the outcome of surgical resection of type III juvenile angiofibroma without preoperative embolizationo in 20 young male patients.
  • PATIENTS AND METHODS: Twenty young male patients with type III JAF (based on Fisch classification by CT/MRI or both), were operated on by endoscopic-assisted midfacial degloving approach without preoperative embolization.
  • Endoscopic transnasal removal of the recurrent JAF was done successfully under local anesthesia in the first patient and under general anesthesia in the second with no recurrence during the follow up period.
  • CONCLUSIONS: Surgical resection of stage III JAF without embolization through endoscopic assisted midfacial degloving approach can be used as an adequate surgical technique with acceptable intraoperative blood loss and low rate of recurrence.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 16904759.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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15. Pradhan B, Thapa N: Juvenile angiofibroma and its management. Nepal Med Coll J; 2009 Sep;11(3):186-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile angiofibroma and its management.
  • This prospective longitudinal study was done to determine extent of tumor and to highlight the importance of lateral rhinotomy approach for nasopharyngeal angiofibroma.
  • Patients with a diagnosis of nasopharyngeal angiofibroma who underwent surgery in Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu from April, 2004 to Jan 2009 were included in the study.
  • Two patients had stage I tumor, 9 patients had stage II disease, other 12 patients had stage III tumor.
  • Most of them had stage III disease and were managed surgically by lateral rhinotomy approach.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 20334067.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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16. Chistiakova VR, Poliaev IuA, Kovshenkova IuD, Vasil'eva NI, Myl'nikov AA, Pronin AE: [Hemostatic provision of surgical treatment of juvenile angiofibromas of the skull base in children]. Vestn Otorinolaringol; 2006;(1):24-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hemostatic provision of surgical treatment of juvenile angiofibromas of the skull base in children].
  • For three years we operated sixty two 7-16-year-old children for angiofibroma of the base of the skull.
  • Neither lethal outcomes nor complications occurred in children during removal of angiofibromas of the base of the skull.
  • [MeSH-major] Angiofibroma / surgery. Blood Loss, Surgical / prevention & control. Hemostatic Techniques. Hemostatics / therapeutic use. Postoperative Hemorrhage / prevention & control. Skull Base Neoplasms / surgery

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  • (PMID = 16482005.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Hemostatics
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17. Cherekaev VA, Belov AI, Kulikovskiĭ PV, Arustamian SR: [Juvenile angiofibroma predominantly extending into the middle cranial fossa and eye-socket]. Zh Vopr Neirokhir Im N N Burdenko; 2006 Jan-Mar;(1):37-9; discussion 39-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile angiofibroma predominantly extending into the middle cranial fossa and eye-socket].
  • The paper analyzes a rare case of juvenile angiofibroma primarily locating in the infratemporal and middle cranial fossa without a nodule in the nasopharynx.
  • Since the disease has started from right facial hypesthesia, neurinoma involving the first and second branches of the trigeminal nerve and spreading to the eye-socket may be suggested.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Skull Base Neoplasms / diagnosis. Skull Base Neoplasms / surgery

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  • (PMID = 16739934.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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18. Thuesen AD, Jakobsen J, Nepper-Rasmussen J: [Treatment of juvenile angiofibroma with particle embolization and endoscopic surgery]. Ugeskr Laeger; 2005 Aug 22;167(34):3167-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment of juvenile angiofibroma with particle embolization and endoscopic surgery].
  • [Transliterated title] Behandling af juvenile angiofibromer med partikelembolisering og endoskopisk kirurgi.
  • INTRODUCTION: Juvenile angiofibroma is a benign, rich vascular nasal tumor, and the biggest complication in surgery is the great loss of blood.
  • DISCUSSION: Endovascular embolization of juvenile angiofibromas followed by endoscopic surgery is considered to be the preferred treatment method today.
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / therapy

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  • [CommentIn] Ugeskr Laeger. 2005 Nov 21;167(47):4482 [16305784.001]
  • (PMID = 16117915.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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19. Prabhu S, Mahesh KP: Tuberous sclerosis with oral angiofibroma: case report. Br J Oral Maxillofac Surg; 2010 Apr;48(3):205-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tuberous sclerosis with oral angiofibroma: case report.
  • Tuberous sclerosis is a multisystem disorder characterised by the formation of hamartomas in various parts of the body.
  • We present a patient who presented with facial angiofibromas (adenoma sebaceum), shagreen patches, and epileptic seizures.
  • Oral papules showed histological features of angiofibroma, which was peculiar to this case.
  • [MeSH-major] Angiofibroma / pathology. Facial Neoplasms / pathology. Mouth Neoplasms / pathology. Tuberous Sclerosis / pathology

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  • [Copyright] 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 19640621.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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20. Tardío JC: Leiomyomatous nodules in a cellular angiofibroma: a hitherto unreported finding. Virchows Arch; 2009 May;454(5):595-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Leiomyomatous nodules in a cellular angiofibroma: a hitherto unreported finding.
  • Cellular angiofibroma is a benign tumor of the superficial soft tissues of the vulvovaginal and inguinoscrotal regions of adult patients.
  • The case of a 44-year-old female with a perineal cellular angiofibroma containing small leiomyomatous nodules is described in this case report.
  • These nodules could probably be originated from smooth muscle differentiation of the spindle cell component of an otherwise conventional cellular angiofibroma.
  • To our knowledge, the finding of distinct leiomyomatous nodules within a cellular angiofibroma has not been previously reported.
  • [MeSH-major] Angiofibroma / pathology. Leiomyoma / pathology. Neoplasms, Multiple Primary / pathology. Soft Tissue Neoplasms / pathology

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  • [Cites] Histopathology. 2004 Oct;45(4):360-8 [15469474.001]
  • [Cites] Am J Surg Pathol. 1997 Jun;21(6):636-44 [9199640.001]
  • [Cites] Am J Surg Pathol. 1998 Jan;22(1):6-16 [9422311.001]
  • [Cites] Am J Surg Pathol. 2004 Nov;28(11):1426-35 [15489646.001]
  • [Cites] Am J Clin Pathol. 1997 Jan;107(1):52-5 [8980367.001]
  • [Cites] Cancer Genet Cytogenet. 2007 Sep;177(2):131-4 [17854668.001]
  • [Cites] Histopathology. 2007 Sep;51(3):410-2 [17727484.001]
  • (PMID = 19301032.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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21. Zhang QF, She CP, Tong YF, Jin Y, Zhang XR: [Endoscopic surgery using the low-temperature plasma radiofrequency for nasopharyngeal angiofibroma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Jul;45(7):578-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopic surgery using the low-temperature plasma radiofrequency for nasopharyngeal angiofibroma].
  • OBJECTIVE: To evaluate the feasibility of endoscopic surgery using the low-temperature plasma radiofrequency for nasopharyngeal angiofibroma (NA).
  • CONCLUSIONS: Endoscopic surgery using low-temperature plasma radiofrequency for nasopharyngeal angiofibroma has many advantages such as less bleeding and total tumor removal.
  • It is a minimally invasive surgical method for nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / surgery. Catheter Ablation / methods. Endoscopy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 21055057.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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22. Elsharkawy AA, Kamal EM, Tawfik A, Zaher A, Kasem M: Juvenile nasopharyngeal angiofibroma with intracranial extension: analysis of 23 Egyptian patients. Int J Pediatr Otorhinolaryngol; 2010 Jul;74(7):755-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma with intracranial extension: analysis of 23 Egyptian patients.
  • The purpose of this study was to present our experience with definitive surgical management of patients with Juvenile nasopharyngeal angiofibroma with intracranial extension.
  • The study included 23 male adolescents with histologically proven juvenile nasopharyngeal angiofibroma.
  • The subcranial transfacial transmaxillary approach avoids the complications of craniotomy and provides adequate access for excision of Juvenile nasopharyngeal angiofibroma with intracranial extradural extension.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods

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  • [Copyright] Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20394990.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Hemostatics
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23. Hori K, Soejima K, Nozaki M, Sakurai H, Takeuchi M, Yamaki T, Iwasaka S, Kono T, Honda T, Isago T: Treatment of facial angiofibroma of tuberous sclerosis using cultured epithelial autografts. Ann Plast Surg; 2006 Oct;57(4):415-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of facial angiofibroma of tuberous sclerosis using cultured epithelial autografts.
  • Treatment of facial angiofibroma of tuberous sclerosis is problematic, because the skin lesions involve entire dermis.
  • Five patients aged from 14 to 33 (mean: 23.6) years old with angiofibroma of tuberous sclerosis were treated with cultured epithelial autografts between 1995 and 2004.
  • [MeSH-major] Angiofibroma / surgery. Epithelium / transplantation. Facial Neoplasms / surgery. Tuberous Sclerosis / complications

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  • (PMID = 16998334.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Schaffer JV, Gohara MA, McNiff JM, Aasi SZ, Dvoretzky I: Multiple facial angiofibromas: a cutaneous manifestation of Birt-Hogg-Dubé syndrome. J Am Acad Dermatol; 2005 Aug;53(2 Suppl 1):S108-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple facial angiofibromas: a cutaneous manifestation of Birt-Hogg-Dubé syndrome.
  • This report describes multiple facial angiofibromas as the predominant initial manifestation of BHDS.
  • The patient had a total of 41 facial papules removed via shave excision, initially for diagnostic and then for therapeutic purposes; histologic evaluation revealed diagnostic features of angiofibroma in 39 lesions and fibrofolliculoma in only 2.
  • BHDS should be considered, along with tuberous sclerosis and multiple endocrine neoplasia type 1, in the differential diagnosis of multiple facial angiofibromas, particularly when onset is in adulthood.
  • [MeSH-major] Angiofibroma / diagnosis. Diseases in Twins / diagnosis. Facial Neoplasms / diagnosis. Neoplastic Syndromes, Hereditary / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 16021156.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / FLCN protein, human; 0 / Proteins; 0 / Proto-Oncogene Proteins; 0 / Tumor Suppressor Proteins
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25. Cai T, Zhou B, Huang Q, Liang X, Ni X, Cui S, Li Y, Wang T, Zang H, Liu H, Liu M, Han D: [Analysis of prognostic factors in endoscopic surgery for juvenile nasopharyngeal angiofibroma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Nov;24(22):1035-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of prognostic factors in endoscopic surgery for juvenile nasopharyngeal angiofibroma].
  • OBJECTIVE: Analyzing the prognostic factors in endoscopic surgery of juvenile nasopharyngeal angiofibromas (JNA).
  • [MeSH-major] Angiofibroma / diagnosis. Nasopharyngeal Neoplasms / diagnosis

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  • (PMID = 21322931.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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26. La Placa M, Gibellini D, Bianchi T, Patrizi A: Overexpression of MLH-1 and psoriasin genes in cutaneous angiofibromas from tuberous sclerosis complex patients. J Cutan Pathol; 2006 Sep;33(9):608-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Overexpression of MLH-1 and psoriasin genes in cutaneous angiofibromas from tuberous sclerosis complex patients.
  • BACKGROUND: Tuberous sclerosis complex (TSC) is associated with mutations in two likely tumor-suppressor genes (TSC1 and TSC2) and characterized by the development of tumor-like growths (angiofibromas) in a variety of tissues and organs, particularly brain and skin.
  • RESULTS: The results obtained by the microarray technology in one hamartoma specimen, confirmed by the RT-PCR results obtained in the same material and in five other hamartoma specimens, demonstrated that TSC-related angiofibromas exhibit significant mRNA overexpression of two genes, represented by MLH-1 and psoriasin.
  • CONCLUSIONS: The overexpression of MLH-1, which codes for a DNA mismatch repair protein, and psoriasin, which codes for a specific chemoattractant factor for CD4+ T cells, implicated in the pathogenesis of inflammatory skin disease, and expressed in excess during abnormal pathways of cell growth, may shed light on the pathogenesis of the proliferative skin lesion.
  • [MeSH-major] Angiofibroma / genetics. Calcium-Binding Proteins / genetics. Carrier Proteins / genetics. Nuclear Proteins / genetics. Skin Neoplasms / genetics. Tuberous Sclerosis / genetics

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  • (PMID = 16965334.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Biomarkers, Tumor; 0 / Calcium-Binding Proteins; 0 / Carrier Proteins; 0 / MLH1 protein, human; 0 / Nuclear Proteins; 0 / RNA, Messenger; 0 / S100 Proteins; 0 / S100A7 protein, human
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27. Lee AN, Stein SL, Cohen LM: Clear cell fibrous papule with NKI/C3 expression: clinical and histologic features in six cases. Am J Dermatopathol; 2005 Aug;27(4):296-300
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clear cell fibrous papule with NKI/C3 expression: clinical and histologic features in six cases.
  • Fibrous papule of the nose is a common benign lesion of dermal fibroblast lineage.
  • Two unusual variants have been described, namely, fibrous papule with granular cells and fibrous papule with clear fibrocytes.
  • We report a second case series (six cases) of clear cell fibrous papule to add to the first series of 9 cases.
  • Clinical differential diagnoses included fibrous papule, verruca, basal cell carcinoma, and a variety of other neoplasms.
  • Recognition of this variant of fibrous papule is important to distinguish this benign lesion from other clear cell neoplasms.
  • [MeSH-major] Nose / pathology. Skin Diseases / pathology

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  • (PMID = 16121048.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Lee CH, Hong CH, Yu HS, Chen GS, Yang KC: Transforming growth factor-β enhances matrix metalloproteinase-2 expression and activity through AKT in fibroblasts derived from angiofibromas in patients with tuberous sclerosis complex. Br J Dermatol; 2010 Dec;163(6):1238-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transforming growth factor-β enhances matrix metalloproteinase-2 expression and activity through AKT in fibroblasts derived from angiofibromas in patients with tuberous sclerosis complex.
  • BACKGROUND: Patients with tuberous sclerosis complex (TSC) develop fibrous tumours in the brain, skin, kidney, heart and lungs due to TSC1/2 mutations.
  • In the skin, patients develop angiofibromas that have vascular and fibrotic components in which transforming growth factor (TGF)-β and matrix metalloproteinase (MMP)-2 are important.
  • OBJECTIVES: To investigate if the TGF-β axis and MMP-2 play an important role in the pathogenesis of TSC angiofibromas.
  • METHODS: Samples from TSC angiofibromas and normal skin were measured for expression of TGF-β and MMP-2 by immunohistochemistry and real-time polymerase chain reaction.
  • Fibroblasts grown from TSC angiofibromas (TSC fibroblasts) were incubated with TGF-β.
  • [MeSH-major] Angiofibroma / enzymology. Fibroblasts / enzymology. Matrix Metalloproteinase 2 / metabolism. Transforming Growth Factor beta / pharmacology. Tuberous Sclerosis / enzymology

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  • [Copyright] © 2010 The Authors. BJD © 2010 British Association of Dermatologists.
  • (PMID = 20698845.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Transforming Growth Factor beta; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 3.4.24.24 / Matrix Metalloproteinase 2
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29. Zhou B, Cai T, Huang Q, Liang XH, Ni X, Wei YX, Cui SJ, Zhang L, Wang T, Liu HC, Liu M, Han DM: [Juvenile nasopharyngeal angiofibroma: endoscopic surgery and follow-up results]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Mar;45(3):180-5
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  • [Title] [Juvenile nasopharyngeal angiofibroma: endoscopic surgery and follow-up results].
  • OBJECTIVE: To present the changes of surgical approaches for the resection of juvenile nasopharyngeal angiofibromas (JNA) and the follow-up results.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 20450693.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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30. Santaolalla F, Araluce I, Zabala A, López A, Garay M, Sanchez JM: Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA). Acta Otolaryngol; 2009 Dec;129(12):1456-62

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA).
  • CONCLUSION: Percutaneous embolization reduces the reappearance of epistaxis and the mean length of hospital stay for patients with intractable epistaxis or juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic. Epistaxis / therapy. Nasopharyngeal Neoplasms / therapy

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  • (PMID = 19922097.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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31. Misago N, Kimura T, Narisawa Y: Fibrofolliculoma/trichodiscoma and fibrous papule (perifollicular fibroma/angiofibroma): a revaluation of the histopathological and immunohistochemical features. J Cutan Pathol; 2009 Sep;36(9):943-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrofolliculoma/trichodiscoma and fibrous papule (perifollicular fibroma/angiofibroma): a revaluation of the histopathological and immunohistochemical features.
  • BACKGROUND: The multiple facial lesions of fibrofolliculoma (FF)/trichodiscoma (TD) and those of fibrous papule (FP; perifollicular fibroma/angiofibroma, AF) are characteristic of Birt-Hogg-Dubé (BHD) syndrome and tuberous sclerosis, respectively.
  • RESULTS: There are common histopathological features in the two lesions, such as the follicular and perifollicular elements, an angiofibromatous element and stellate fibrocytes.
  • [MeSH-major] Hair Follicle / metabolism. Hair Follicle / pathology. Hamartoma / metabolism. Hamartoma / pathology. Skin Diseases / metabolism. Skin Diseases / pathology

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  • (PMID = 19674199.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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32. Margalit N, Wasserzug O, De-Row A, Abergel A, Fliss DM, Gil Z: Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article. J Neurosurg Pediatr; 2009 Aug;4(2):113-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article.
  • OBJECT: The purpose of this study was to describe the surgical treatment and outcomes of patients with intracranial extension of juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / surgery. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / surgery

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  • [CommentIn] J Neurosurg Pediatr. 2012 Mar;9(3):336-7; author reply 337 [22380966.001]
  • (PMID = 19645542.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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33. Sciarretta V, Pasquini E, Frank G, Modugno GC, Cantaroni C, Mazzatenta D, Farneti G: Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases. Am J Rhinol; 2006 Jan-Feb;20(1):64-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases.
  • BACKGROUND: The endoscopic approach can be used successfully for the treatment of benign tumors such as fibroosseous and vascular lesions, pleomorphic adenoma, glioma, meningioma, and schwannoma.
  • METHODS: Thirty-three patients diagnosed with benign tumors of the nasal cavity and paranasal sinuses and treated using an endoscopic approach were reviewed retrospectively.
  • The mean follow-up was 28 months and only two recurrences (6%) were observed in the juvenile angiofibroma group and in the case of the fibrous dysplasia associated to aneurysmal bone cyst, respectively, 20 and 24 months postoperatively.
  • CONCLUSION: In selected cases, endoscopic surgery can be considered an effective treatment for the resection of benign tumors involving the sinonasal tract.
  • [MeSH-minor] Adolescent. Adult. Aged. Angiofibroma / surgery. Child. Child, Preschool. Female. Follow-Up Studies. Glioma / surgery. Hemangioma, Cavernous / surgery. Humans. Magnetic Resonance Imaging. Male. Meningioma / surgery. Middle Aged. Osteoma / surgery. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16539297.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Schick B, Wemmert S, Bechtel U, Nicolai P, Hofmann T, Golabek W, Urbschat S: Comprehensive genomic analysis identifies MDM2 and AURKA as novel amplified genes in juvenile angiofibromas. Head Neck; 2007 May;29(5):479-87
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comprehensive genomic analysis identifies MDM2 and AURKA as novel amplified genes in juvenile angiofibromas.
  • BACKGROUND: Frequent beta-catenin mutations have been detected in juvenile angiofibromas, but the tumor pathogenesis remains unknown.
  • CONCLUSION: Metaphase-CGH results confirmed numerous chromosomal aberrations in juvenile angiofibromas.
  • AURKA and MDM2 were identified as interesting novel amplified genes in juvenile angiofibromas.
  • [MeSH-major] Angiofibroma / genetics. Chromosome Aberrations. Head and Neck Neoplasms / genetics. Protein-Serine-Threonine Kinases / genetics. Proto-Oncogene Proteins c-mdm2 / genetics

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  • [Copyright] (c) 2006 Wiley Periodicals, Inc.
  • (PMID = 17120309.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.11.1 / AURKA protein, human; EC 2.7.11.1 / Aurora Kinase A; EC 2.7.11.1 / Aurora Kinases; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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35. Tyagi I, Syal R, Goyal A: Recurrent and residual juvenile angiofibromas. J Laryngol Otol; 2007 May;121(5):460-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent and residual juvenile angiofibromas.
  • INTRODUCTION: In the surgical management of juvenile nasopharyngeal angiofibromas the possibility of recurrences and residual tumours is always there.
  • This study was undertaken to predict the prognostic factors determining recurrence of juvenile nasopharyngeal angiofibroma and to find out the usual sites of these tumours.
  • MATERIAL AND METHODS: The medical records of 95 patients with histologically proven juvenile nasopharyngeal angiofibroma were reviewed retrospectively.
  • RESULTS: Complete removal of the juvenile nasopharyngeal angiofibroma was achieved in 78 (82 per cent) of the cases in a single operation.
  • CONCLUSIONS: Extensions into the pterygoid fossa and basisphenoid, erosion of the clivus, intracranial extensions medial to the cavernous sinus, invasion of the sphenoid diploe through a widened pterygoid canal, feeders from the internal carotid artery, a young age and a residual tumour were risk factors found associated with recurrence of juvenile nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Neoplasm Recurrence, Local

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  • (PMID = 17210091.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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36. Porras Alonso EC, Benito Navarro JR, Fernandez Roche JA, Rodriguez Fernández-Freire A: [Child nasopharyngeal angiofibroma]. An Otorrinolaringol Ibero Am; 2005;32(5):483-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Child nasopharyngeal angiofibroma].
  • [Transliterated title] Angiofibroma nasofaringeo infantil.
  • Angiofibromas are benign tumors, highly vascularized, that affect male adolescents and young men.
  • We present a clinical case of an 11-year-old patient with an angiofibroma of the nasopharynx, reviewing the etiopathogenic theories and current surgical approaches.
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / radiography. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / radiography

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  • (PMID = 16318092.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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37. Gramann M, Wendler O, Haeberle L, Schick B: Prominent collagen type VI expression in juvenile angiofibromas. Histochem Cell Biol; 2009 Jan;131(1):155-64

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prominent collagen type VI expression in juvenile angiofibromas.
  • Although, juvenile angiofibromas (JAs) often exhibit an aggressive growth pattern, the collagen type VI expression of this fibrovascular tumour has not been addressed so far.
  • [MeSH-major] Angiofibroma / metabolism. Collagen Type VI / metabolism

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  • (PMID = 18797915.001).
  • [ISSN] 1432-119X
  • [Journal-full-title] Histochemistry and cell biology
  • [ISO-abbreviation] Histochem. Cell Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Collagen Type VI
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38. Chen E, Fletcher CD: Cellular angiofibroma with atypia or sarcomatous transformation: clinicopathologic analysis of 13 cases. Am J Surg Pathol; 2010 May;34(5):707-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cellular angiofibroma with atypia or sarcomatous transformation: clinicopathologic analysis of 13 cases.
  • Cellular angiofibroma is a mesenchymal neoplasm that is characterized by a bland spindle cell component, morphologically reminiscent of spindle cell lipoma, and thick-walled vessels.
  • An earlier study of 51 cases from our group showed that the tumor follows a benign course without any tendency for recurrence.
  • The biologic significance of atypia or sarcomatous transformation in cellular angiofibroma remains uncertain.
  • In this study, we characterized clinicopathologic features in 13 cases of cellular angiofibroma with morphologic atypia or sarcomatous transformation.
  • Thirteen cases with atypia or sarcomatous transformation among 154 usual cellular angiofibromas identified between 1993 and 2009 were retrieved from consultation files.
  • There were 4 cases of cellular angiofibroma with atypia.
  • Three showed severely atypical cells as scattered foci within the cellular angiofibroma.
  • There were 9 cases of cellular angiofibroma with morphologic features of sarcomatous transformation.
  • Three of these 9 cases showed discrete nodule(s) closely resembling atypical lipomatous tumor within usual cellular angiofibroma.
  • By immunohistochemistry, atypical cells and sarcomatous areas showed either multifocal or more diffuse p16 expression compared with either scattered or negative expression in the conventional cellular angiofibroma.
  • One patient died of metastatic carcinoma of unknown primary site 27 months after the diagnosis of cellular angiofibroma with sarcomatous transformation.
  • Cellular angiofibroma with atypia or morphologic sarcomatous transformation occurs predominantly in the subcutaneous tissue of the vulva and, as yet, shows no evident tendency to recur based on limited clinical follow-up available for 7 cases.
  • The sarcomatous component can show variable features including atypical lipomatous tumor, pleomorphic liposarcoma, and pleomorphic sarcoma NOS.
  • [MeSH-major] Angiofibroma / pathology. Cell Transformation, Neoplastic. Sarcoma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 20305534.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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39. Rzaev RM: [Surgical policy in patients with basally advanced form of juvenile nasopharyngeal angiofibroma]. Vestn Otorinolaringol; 2005;(3):29-33

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical policy in patients with basally advanced form of juvenile nasopharyngeal angiofibroma].
  • The authors has modified surgical policy in a basicranially extending form of juvenile nasopharyngeal angiofibroma (JNA) which is classified into tumors of stage I, II and III.
  • [MeSH-major] Angiofibroma. Nasopharyngeal Neoplasms. Otorhinolaryngologic Surgical Procedures / methods

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  • (PMID = 16034343.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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40. Carrillo JF, Maldonado F, Albores O, Ramírez-Ortega MC, Oñate-Ocaña LF: Juvenile nasopharyngeal angiofibroma: clinical factors associated with recurrence, and proposal of a staging system. J Surg Oncol; 2008 Aug 1;98(2):75-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: clinical factors associated with recurrence, and proposal of a staging system.
  • BACKGROUND: Juvenile nasopharyngeal angiofibroma (JNA) is a vascular tumor of the nasopharynx.
  • Clinical, radiological and therapeutic data were assessed for recurrence- and disease free survival-associated prognostic factors.
  • CONCLUSION: Our system stratifies recurrence risk and disease-free survival efficiently.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Neoplasm Staging
  • [MeSH-minor] Adolescent. Adult. Disease-Free Survival. Humans. Male. Multivariate Analysis. Prognosis. Radiotherapy Dosage. Retrospective Studies

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  • [CommentIn] J Surg Oncol. 2008 Aug 1;98(2):73 [18623035.001]
  • (PMID = 18623038.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. Zhou W, Fang J, Ni X, Huang Z, Wang Q, Chen X, Chen XZ, Xu H: [The modified rhinotomy for treatment of tumors involving skull base]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Apr;24(7):301-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among that 2 patient were with juvenal angiofibroma treated by combined with maxillary transposition and pterional and zygomatic approach, and 2 cases were with craniofacial approach.

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  • (PMID = 20545113.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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42. Haq MZ, Dubey I, Khess CR, Das U, Kumar R: Bipolar disorder and tuberous sclerosis complex: is it a mere coincidence? CNS Spectr; 2009 Nov;14(11):643-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bipolar disorder and tuberous sclerosis complex: is it a mere coincidence?
  • There are very few reports of bipolar disorder in TSC.
  • The authors present the case of a patient with TSC having bipolar disorder manifesting as manic as well as depressive episodes.
  • The diagnosis of TSC was based on the presence of facial angiofibromas, enamel pits, and shagreen patches on clinical examination, and the presence of cortical tubers and calcified subependymal nodules on neuroimaging.
  • To our knowledge, this is the first report of TSC with bipolar disorder having both manic as well as depressive episodes.
  • The nature of association between TSC and bipolar disorder, and its clinical implications are discussed.
  • [MeSH-major] Bipolar Disorder / etiology. Tuberous Sclerosis / complications


43. Gore P, Theodore N, Brasiliense L, Kim LJ, Garrett M, Nakaji P, Gonzalez LF, McDougall CG, Albuquerque FC: The utility of onyx for preoperative embolization of cranial and spinal tumors. Neurosurgery; 2008 Jun;62(6):1204-11; discussion 1211-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tumors included three juvenile nasal angiofibromas, two meningiomas, two hemangioblastomas, two metastases (renal cell and thyroid), and one giant cell tumor.

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  • (PMID = 18824987.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Onyx copolymer; 0 / Polyvinyls; YOW8V9698H / Dimethyl Sulfoxide
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44. Szyfter W, Borucki Ł, Balcerowiak A: [Endoscopic surgery for selected tumors of the nose and paranasal sinuses--practical sense of the four hands technique]. Otolaryngol Pol; 2008;62(2):170-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Two major pathologies are present in the literature, the inverted papilloma and the angiofibroma.

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  • (PMID = 18637441.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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45. Hoff AO, Hauache OM: [Multiple endocrine neoplasia type 1 (MEN 1): clinical, biochemical and molecular diagnosis and treatment of the associated disturbances]. Arq Bras Endocrinol Metabol; 2005 Oct;49(5):735-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In addition, these patients can present with cutaneous manifestations such as angiofibromas and collagenomas, and can develop other neoplastic manifestations including carcinoids, thyroid tumors, adrenal adenomas, lipomas, pheochromocytomas and meningiomas.

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  • (PMID = 16444356.001).
  • [ISSN] 0004-2730
  • [Journal-full-title] Arquivos brasileiros de endocrinologia e metabologia
  • [ISO-abbreviation] Arq Bras Endocrinol Metabol
  • [Language] por
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / MEN1 protein, human; 0 / Proto-Oncogene Proteins
  • [Number-of-references] 84
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46. Benatiya AI, Bouayed MA, Touiza E, Daoudi K, Mernissi FZ, Tahri H: [Bourneville's tuberous sclerosis. A case report]. J Fr Ophtalmol; 2005 Dec;28(10):e11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] La sclérose tubéreuse de Bourneville. A propos d'un cas.
  • INTRODUCTION: Bourneville's tuberous sclerosis (BTS) is an autosomal dominant phakomatosis characterized by the development of a benign hamartoma-like tumor, which is usually located in the skin, kidney, heart, brain, and eyes.
  • We present here a case of a retinal BTS of late diagnosis.
  • Dermatologic examination also showed facial angiofibromas.
  • The chest X-ray, renal scan, heart scan and a CT scan of the brain failed to show any other localizations of the disease.

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  • (PMID = 16395191.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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47. Gil Z, Constantini S, Spektor S, Abergel A, Khafif A, Beni-Adani L, Leonor TL, DeRowe A, Fliss DM: Skull base approaches in the pediatric population. Head Neck; 2005 Aug;27(8):682-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eighteen cases (27%) involved malignant tumors, and 49 (73%) involved benign tumors.
  • The most common benign tumors were craniopharyngioma (n = 10) and juvenile nasopharyngeal angiofibroma (n = 8).
  • Five children, two with optic glioma and one each with squamous cell carcinoma, ependymoma, and germinoma, have died of their disease.

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  • [Copyright] Copyright 2005 Wiley Periodicals, Inc.
  • (PMID = 15957193.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. McCluggage WG: A review and update of morphologically bland vulvovaginal mesenchymal lesions. Int J Gynecol Pathol; 2005 Jan;24(1):26-38
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Vulvovaginal mesenchymal lesions composed of morphologically bland spindle-shaped cells often pose a particular diagnostic problem for the surgical pathologist not only because of the rarity of these lesions but also because of the wide array of entities with overlapping morphologic features.
  • Lesions that are relatively specific to the vulvovaginal region include well-known neoplasms such as aggressive angiomyxoma and angiomyofibroblastoma as well as more recently described lesions such as cellular angiofibroma and superficial cervicovaginal myofibroblastoma.
  • [MeSH-minor] Angiofibroma / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Mesoderm. Myxoma / pathology. Neoplasms, Muscle Tissue / pathology. Polyps / pathology

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  • (PMID = 15626915.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 81
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49. Cole RP, Widdowson D, Moore JC: Outcome of erbium:yttrium aluminium garnet laser resurfacing treatments. Lasers Med Sci; 2008 Oct;23(4):427-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Erbium:yttrium aluminium garnet (erbium:YAG) laser treatment was used to resurface skin abnormalities in patients suffering from conditions that included epidermal naevi, tuberous sclerosis, angiofibromata, neurofibromatosis, and scarring caused by acne or other means.
  • [MeSH-major] Laser Therapy / instrumentation. Lasers, Solid-State. Skin Diseases / surgery

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  • (PMID = 18074165.001).
  • [ISSN] 0268-8921
  • [Journal-full-title] Lasers in medical science
  • [ISO-abbreviation] Lasers Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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50. Parikh SR, Cuellar H, Sadoughi B, Aroniadis O, Fried MP: Indications for image-guidance in pediatric sinonasal surgery. Int J Pediatr Otorhinolaryngol; 2009 Mar;73(3):351-6
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  • Indications for surgery included chronic (30.3%) and acute (12.1%) rhinosinusitis, nasopharyngeal angiofibroma (9.1%), allergic rhinosinusitis (9.1%) and allergic fungal sinusitis (9.1%).
  • In our population, image-guidance was only used for advanced sinonasal procedures where there was an anatomic abnormality or disease that extended to the sphenoid sinus, frontal sinus, orbit, or skull base.

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  • (PMID = 19157578.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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51. Jóźwiak J, Galus R: Molecular implications of skin lesions in tuberous sclerosis. Am J Dermatopathol; 2008 Jun;30(3):256-61
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  • Tuberous sclerosis (TS), neurocutaneous disorder resulting from the mutation of 1 of 2 genes, TSC1 or TSC2, is often associated with the formation of hamartomatous lesions in various organ systems, including the skin.
  • TS patients may present with hypomelanic macules, confetti-like spots, facial angiofibromas, ungual fibromas, shagreen patches, forehead plaques, and other dermatological signs.
  • Little is known however on molecular links connecting disease pathogenesis and formation of such hamartomas.
  • In the current review, we describe molecular pathways thought to be responsible for the development of the disease and show how their upregulation may affect the skin.
  • [MeSH-major] Proto-Oncogene Proteins c-akt / genetics. Skin Diseases / genetics. Tuberous Sclerosis / genetics


52. Medeiros F, Erickson-Johnson MR, Keeney GL, Clayton AC, Nascimento AG, Wang X, Oliveira AM: Frequency and characterization of HMGA2 and HMGA1 rearrangements in mesenchymal tumors of the lower genital tract. Genes Chromosomes Cancer; 2007 Nov;46(11):981-90
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  • We evaluated 90 cases of mesenchymal tumors of the lower genital tract that comprised 42 AAMs, 18 AMFs, 6 cellular angiofibromas, 5 fibroepithelial stromal polyps, 15 genital leiomyomas, 3 superficial angiomyxomas, and 1 spindle cell lipoma.

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  • [Copyright] Copyright (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17654722.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Complementary; 0 / HMGA Proteins
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53. Schwartz RA, Fernández G, Kotulska K, Jóźwiak S: Tuberous sclerosis complex: advances in diagnosis, genetics, and management. J Am Acad Dermatol; 2007 Aug;57(2):189-202
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  • The classic triad is seizures, mental retardation, and cutaneous angiofibromas.
  • [MeSH-minor] Diagnosis, Differential. Humans. Molecular Diagnostic Techniques. Mutation. Protein Kinases / drug effects. Protein Kinases / metabolism. Sirolimus / therapeutic use. Skin Diseases / etiology. Skin Diseases / pathology. TOR Serine-Threonine Kinases. Tooth Diseases / etiology. Tooth Diseases / pathology


54. Marini F, Falchetti A, Del Monte F, Carbonell Sala S, Gozzini A, Luzi E, Brandi ML: Multiple endocrine neoplasia type 1. Orphanet J Rare Dis; 2006;1:38
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  • The sporadic form presents with two of the three principal MEN1-related endocrine tumours (parathyroid adenomas, entero-pancreatic tumours and pituitary tumours) within a single patient, while the familial form consists of a MEN1 case with at least one first degree relative showing one of the endocrine characterising tumours.
  • Other endocrine and non-endocrine lesions, such as adrenal cortical tumours, carcinoids of the bronchi, gastrointestinal tract and thymus, lipomas, angiofibromas, collagenomas have been described.
  • [MeSH-minor] Adolescent. Adrenal Cortex Neoplasms / diagnosis. Adult. Aged. Aged, 80 and over. Angiofibroma / diagnosis. Carcinoid Tumor / diagnosis. Child. Facial Neoplasms / diagnosis. Female. Gastrinoma / diagnosis. Genetic Testing / methods. Humans. Insulinoma / diagnosis. Lipoma / diagnosis. Male. Meningioma / diagnosis. Middle Aged. Prolactinoma / diagnosis. Proto-Oncogene Proteins / genetics. Thyroid Neoplasms / diagnosis. Vasoactive Intestinal Peptide / blood. Vasoactive Intestinal Peptide / secretion. Young Adult

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  • (PMID = 17014705.001).
  • [ISSN] 1750-1172
  • [Journal-full-title] Orphanet journal of rare diseases
  • [ISO-abbreviation] Orphanet J Rare Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / MEN1 protein, human; 0 / Proto-Oncogene Proteins; 37221-79-7 / Vasoactive Intestinal Peptide
  • [Number-of-references] 64
  • [Other-IDs] NLM/ PMC1594566
  • [General-notes] NLM/ Original DateCompleted: 20070618
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55. Hatem R, Lamia T, Raouf C, Azza S, Karima Z, Nadia E, Najla M, Radhi H: [Embolization of head and neck hypervascular lesions. A retrospective study of 5 cases]. Tunis Med; 2005 Oct;83(10):627-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Embolisation des lesions hypervasculaires de la face et du cou. Etude rétrospective à propos de 5 cas.
  • Lesions were distributed as follow: nasal angiofibroma (n = I), nasal angioleiomyoma (n = I), nasopharyngeal angiofibroma (n = I), aneurysmal bone cyst in the posterior element of the second cervical vertebra (n = I) and AVM of the inferior lip (n = I).

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  • (PMID = 16370215.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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56. Padilla Parrado M, Díaz Sastre MA, Jiménez Antolín JA, Caro García MA: [Juvenile nasopharyngeal angiofibroma]. An Otorrinolaringol Ibero Am; 2005;32(4):361-71

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  • [Title] [Juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Angiofibroma nasofaringeo juvenil. Situación actual.
  • Juvenile Juvenile nasopharyngeal angiofibroma (JNA) is a benign and highly vascular tumor.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 16156366.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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57. Thuesen AD, Jakobsen J, Nepper-Rasmussen J: [Juvenile angiofibroma]. Ugeskr Laeger; 2005 Aug 22;167(34):3163-6

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  • [Title] [Juvenile angiofibroma].
  • [Transliterated title] Juvenile angiofibromer.
  • Juvenile angiofibroma is a rare, benign, rich vascular tumor, and approximately one new case is diagnosed in Denmark each year.
  • Through the years, the treatment of juvenile angiofibroma has included many methods, including surgical excision, electrocoagulation, interstitial or external radiation therapy, cryosurgery, hormone administration and chemotherapy.
  • [MeSH-major] Angiofibroma. Nasopharyngeal Neoplasms

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  • [CommentIn] Ugeskr Laeger. 2005 Nov 21;167(47):4482 [16305784.001]
  • (PMID = 16117914.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 25
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58. Gramann M, Wendler O, Haeberle L, Schick B: Expression of collagen types I, II and III in juvenile angiofibromas. Cells Tissues Organs; 2009;189(6):403-9
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  • [Title] Expression of collagen types I, II and III in juvenile angiofibromas.
  • Extracellular matrix components have rarely been the focus of interest in juvenile angiofibroma (JA) studies.
  • [MeSH-major] Angiofibroma / metabolism. Fibrillar Collagens / metabolism

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  • [Copyright] (c) 2008 S. Karger AG, Basel.
  • (PMID = 18815441.001).
  • [ISSN] 1422-6421
  • [Journal-full-title] Cells, tissues, organs
  • [ISO-abbreviation] Cells Tissues Organs (Print)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Fibrillar Collagens
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59. Wendler O, Schäfer R, Schick B: Mast cells and T-lymphocytes in juvenile angiofibromas. Eur Arch Otorhinolaryngol; 2007 Jul;264(7):769-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mast cells and T-lymphocytes in juvenile angiofibromas.
  • Juvenile angiofibroma (JA) is regarded as a benign fibrovascular tumour of unknown aetiology.
  • Due to its fibrovascular architecture the fibrous and vascular tumour component have been in the focus of most studies.
  • Western blot analysis supported finding of remarkable expression of the mast cell markers tryptase and chymase in JAs and indicated for both proteins similar but also different molecular weights than being observed in NM.
  • Regarding these observations JAs are certainly not only built up by vascular cells and fibrous stroma cells.
  • [MeSH-major] Angiofibroma / pathology. CD4-Positive T-Lymphocytes / pathology. CD8-Positive T-Lymphocytes / pathology. Mast Cells / pathology. Nose Neoplasms / pathology

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  • (PMID = 17310347.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.21.39 / Chymases; EC 3.4.21.59 / Tryptases
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60. Nicolai P, Villaret AB, Farina D, Nadeau S, Yakirevitch A, Berlucchi M, Galtelli C: Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases. Am J Rhinol Allergy; 2010 Mar-Apr;24(2):e67-72
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  • [Title] Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases.
  • BACKGROUND: At present, transnasal endoscopic surgery is considered a viable option in the management of small-intermediate size juvenile angiofibromas (JAs).
  • The lesions were classified according to Andrews (Andrews JC, et al., The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach, Laryngoscope 99:429-437, 1989) and Onerci (Onerci M, et al.
  • Juvenile nasopharyngeal angiofibroma: A revised staging system, Rhinology 44:39-45, 2006) staging systems.
  • RESULTS: Lesions were classified as follows: stage I, n = 5; stage II, n = 24; stage IIIa, n = 14; stage IIIb, n = 3 according to Andrews classification system; stage 1, n = 9; stage II, n = 12; stage III, n = 26 according to Onerci's system.
  • In four (8.7%) cases, suspicious residual disease was detected by MRI.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nose Neoplasms / surgery

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  • (PMID = 20338105.001).
  • [ISSN] 1945-8932
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Sennes LU, Fortes FS, Butugan O, Saldiva PH, Bernardi FC: Tissue maturation correlating to clinical manifestations in juvenile angiofibroma. Ann Otol Rhinol Laryngol; 2005 Sep;114(9):705-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tissue maturation correlating to clinical manifestations in juvenile angiofibroma.
  • OBJECTIVES: Juvenile nasopharyngeal angiofibroma is a rare benign tumor that affects young male patients and shows a characteristic development from its origin.
  • It is not a true neoplasm, but shows features of vascular processes, developing into a more fibrous condition.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 16240934.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Giavroglou C, Constantinidis J, Triaridis S, Daniilidis J, Dimitriadis A: [Angiographic evaluation and embolization of juvenile nasopharyngeal angiofibroma]. HNO; 2007 Jan;55(1):36-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiographic evaluation and embolization of juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Juveniles Angiofibrom: Angiographische Diagnostik und präoperative Embolisation.
  • OBJECTIVE: In juvenile nasopharyngeal angiofibroma (JNA), analysis of tumor extension and blood supply is useful for controlling intraoperative bleeding and helps in determining the appropriate surgical approach.
  • [MeSH-major] Angiofibroma / diagnostic imaging. Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / diagnostic imaging. Nasopharyngeal Neoplasms / therapy. Neoplasm Recurrence, Local / prevention & control

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  • (PMID = 16775738.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
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63. Cherekaev VA, Gol'bin DA, Kapitanov DN, Belov AI, Arustamian SR, Gromova VV, Imaev AA: [Surgical treatment of extensive craniofacial juvenile angiofibromas]. Zh Vopr Neirokhir Im N N Burdenko; 2009 Apr-Jun;(2):9-14; discussion 14-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment of extensive craniofacial juvenile angiofibromas].
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor occurring almost exclusively in adolescent and young adult males.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods

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  • (PMID = 19569543.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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64. Kapidzić A, Sutalo K: [Surgical treatment of juvenile nasopharyngeal angifibroma]. Med Arh; 2006;60(5):296-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment of juvenile nasopharyngeal angifibroma].
  • [Transliterated title] Operativno lijecenje juvenilnog nazofaringealnog angiofibroma.
  • Juvenile nasopharyngeal angiofibroma represents non-incapsulated benign tumor.
  • Three patients with juvenile nasopharyngeal angiofibroma that underwent surgery in a five year period (2001-2005) at the ENT Clinic of the University Clinical Center in Sarajevo are evaluated in this paper.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 16944730.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] bos
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bosnia and Herzegovina
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65. Shcherbenko OI, Rodionov MV, Lebedev VA, Kliachkina NB: [Efficacy of remote gamma-therapy in patients with juvenile angiofibroma of the base of the skull]. Vestn Otorinolaringol; 2008;(3):26-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Efficacy of remote gamma-therapy in patients with juvenile angiofibroma of the base of the skull].
  • The results of radiation therapy of 48 patients with juvenile nasopharyngeal angiofibroma were analysed.
  • [MeSH-major] Angiofibroma / radiotherapy. Gamma Rays / therapeutic use. Skull Base Neoplasms / radiotherapy

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  • (PMID = 18833092.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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66. Rzaev RM: [The role of angiography in diagnosis and surgical treatment of patients with juvenile angiofibroma of the nasopharynx]. Vestn Otorinolaringol; 2007;(4):18-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The role of angiography in diagnosis and surgical treatment of patients with juvenile angiofibroma of the nasopharynx].
  • 22 of them had juvenile nasopharyngeal angiofibroma (JNA), 8 patients had early cancer.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Angiography / methods. Carotid Arteries / radiography. Nasopharyngeal Neoplasms / diagnosis. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 17828107.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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67. Perez EG, Paranaíba LR, Bonan PR, Orsi Júnior JM, Oliveira AM, Martelli Júnior H: [Tuberous sclerosis: evaluation of myofibroblasts in cutaneous angiofibromas - case report]. An Bras Dermatol; 2010 Jan-Feb;85(1):84-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Tuberous sclerosis: evaluation of myofibroblasts in cutaneous angiofibromas - case report].
  • [Transliterated title] Esclerose tuberosa: avaliação de miofibroblastos em angiofibromas cutâneos - relato de caso.
  • Tuberous sclerosis is a rare autosomal dominant disorder.
  • The objective of this study is to describe clinical and histopathological characteristics of tuberous sclerosis and to conduct an immunohistochemical evaluation of myofibroblasts in cutaneous angiofibromas present in this condition.
  • Since alpha-SMA is a specific marker for myofibroblasts, this result suggests that myofibroblasts are not involved in cutaneous angiofibromas present in the tuberous sclerosis case reported.
  • [MeSH-major] Angiofibroma / complications. Angiofibroma / pathology. Fibroblasts / pathology. Skin Neoplasms / complications. Skin Neoplasms / pathology. Tuberous Sclerosis / complications

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  • (PMID = 20464093.001).
  • [ISSN] 1806-4841
  • [Journal-full-title] Anais brasileiros de dermatologia
  • [ISO-abbreviation] An Bras Dermatol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
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68. Falkner JA, Falkner JW, Andrews PC: ProteomeCommons.org JAF: reference information and tools for proteomics. Bioinformatics; 2006 Mar 1;22(5):632-3
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] ProteomeCommons.org JAF: reference information and tools for proteomics.
  • The Java Analysis Framework (JAF) for proteomics provides a freely usable, open-source library of Java code that abstracts all of the aforementioned data, enabling more rapid development of proteomics tools.
  • The JAF also includes several user tools that can be run directly from a web browser.

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  • (PMID = 16434446.001).
  • [ISSN] 1367-4803
  • [Journal-full-title] Bioinformatics (Oxford, England)
  • [ISO-abbreviation] Bioinformatics
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / P41-RR018627
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Proteins
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69. Ngan BY, Forte V, Campisi P: Molecular angiogenic signaling in angiofibromas after embolization: implications for therapy. Arch Otolaryngol Head Neck Surg; 2008 Nov;134(11):1170-6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular angiogenic signaling in angiofibromas after embolization: implications for therapy.
  • OBJECTIVES: To examine (1) the molecular angiogenic relationship between endothelial and stromal cells of angiofibromas and how this may elucidate the pathogenesis of angiofibromas and (2) the effects of embolization on the expression of angiotrophic factors and proapoptotic and antiapoptotic factors within the tumor.
  • DESIGN: The expression of mesenchymal and endothelial stem/progenitor cell-associated proteins (MECAPs) such as proangiogenic cytokine vascular endothelial growth factor (VEGF), VEGF receptors (VEGFR1, VEGFR2, and VEGFR3), angiopoietin receptors (Tie-1 and Tie-2), and stem cell subset marker CD133 was assessed by immunohistological staining in 7 embolized angiofibroma specimens.
  • Expression of proapoptotic Bax, antiapoptotic Bcl-2 and Bcl-xL, nuclear proliferation protein MiB-1, and hypoxia-inducible factor 1alpha (Hif-1alpha) in peri-ischemic areas of the embolized angiofibromas was also assessed.
  • PATIENTS: Seven patients (identified from medical records, January 1, 2001, through December 31, 2005) who were diagnosed as having juvenile angiofibroma and who underwent surgical treatment.
  • RESULTS: All angiofibroma specimens expressed the stem cell subset marker CD133 and MECAPs except VEGFR3 (a few cases).
  • Specific angiogenesis blockers may represent a novel treatment strategy for angiofibromas.
  • [MeSH-major] Angiofibroma / genetics. Angiofibroma / therapy. Biomarkers, Tumor / genetics. Embolization, Therapeutic. Neoplasm Proteins / genetics. Otorhinolaryngologic Neoplasms / genetics. Otorhinolaryngologic Neoplasms / therapy. Signal Transduction / genetics

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  • (PMID = 19015446.001).
  • [ISSN] 1538-361X
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inducing Agents; 0 / Biomarkers, Tumor; 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Neoplasm Proteins; 0 / Vascular Endothelial Growth Factor A
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70. Durko M, Murlewska A, Gryczyński M, Ratyńska M, Pietruszewska W: [Angiofibroma of the nasal cavity and anterior ethmoid cells--problems in differential diagnosis]. Otolaryngol Pol; 2007;61(5):736-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiofibroma of the nasal cavity and anterior ethmoid cells--problems in differential diagnosis].
  • [Transliterated title] Angiofibroma jamy nosa i komórek sitowych przednich u kobiety--problemy diagnostyki róznicowej.
  • BACKGROUND: Nasal angiofibromas are commonly called juvenile nasal angiofibromas (JNA) because of the almost exclusive occurrence in adolescent males.
  • It is a relatively rare benign fibrovascular tumor originating in the posterior lateral wall of the nasopharynx with only a very few cases diagnosed in females.
  • CASE REPORT: Authors present a case of a 26 y.o. woman with JNA in left nasal cavity with extension to the anterior left ethmoid cells diagnosed and surgically treated at the ENT Department, Medical University of Lodz.
  • CONCLUSION: Although angiofibroma in females is an extremely rare tumor of a sinonasal tract it should be taken into consideration in the differential diagnosis of all nasal cavity tumors (especially solitary fibrous tumor).
  • [MeSH-major] Angiofibroma / pathology. Ethmoid Sinus / pathology. Nose Neoplasms / pathology

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  • (PMID = 18552009.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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71. Duerr S, Wendler O, Aigner T, Karosi S, Schick B: Metalloproteinases in juvenile angiofibroma--a collagen rich tumor. Hum Pathol; 2008 Feb;39(2):259-68
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metalloproteinases in juvenile angiofibroma--a collagen rich tumor.
  • MMPs with gelatinase/collagenase activity have not yet been studied in juvenile angiofibroma, a unique fibrovascular tumor with prominent collagen expression.
  • Quantitative real-time polymerase chain reaction studies, Western blot analysis, immunofluorescence studies, gel zymography, and in situ zymography were used to analyze MMP-1, MMP-2, MMP-9, MMP-13, MMP-14, TIMP-1, and TIMP-2 in 9 juvenile angiofibromas and 2 inferior nasal turbinate specimens.
  • Western blot analysis detected more prominent MMP-1, MMP-2, and MMP-9 protein levels in juvenile angiofibromas compared with inferior nasal turbinates, but not MMP-13, MMP-14, TIMP-1, and TIMP-2.
  • Gel zymography indicated increased MMP-2 and MMP-9 gelatinase activity in juvenile angiofibromas compared with inferior nasal turbinates.
  • This study indicates significant expression of MMPs with gelatinase/collagenase activity in juvenile angiofibromas with evidence of a disturbed balance of MMPs to TIMPs toward enhanced MMP activity.
  • [MeSH-major] Angiofibroma / enzymology. Biomarkers, Tumor / metabolism. Collagen / metabolism. Metalloproteases / metabolism. Nose Neoplasms / enzymology

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  • (PMID = 17950779.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Tissue Inhibitor of Metalloproteinase-1; 127497-59-0 / Tissue Inhibitor of Metalloproteinase-2; 9007-34-5 / Collagen; EC 3.4.- / Metalloproteases
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72. Hernández Monge A, Estrada Moscoso I, Márquez Iribe P, Alanis Fuentes J, Pacheco Pineda R: [Vulvar cellular angiofibroma. A report of a case and bibliographic review]. Ginecol Obstet Mex; 2006 Sep;74(9):499-502
MedlinePlus Health Information. consumer health - Vulvar Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Vulvar cellular angiofibroma. A report of a case and bibliographic review].
  • [Transliterated title] Angiofibroma celular de la vulva. Comunicación de un caso y revisión de la bibliografía.
  • The vulvar cellular angiofibroma is a rare mesenchymal tumor.
  • Misdiagnosis is common and it can be confounded with spindle cell lipoma, hydrocele of the canal of Nuck, fibromas, angiomyofibroblastoma and many other mesenchymal tumors.
  • [MeSH-major] Angiofibroma / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 17133966.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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73. Dere H, Ozcan KM, Ergul G, Bahar S, Ozcan I, Kulacoglu S: Extranasopharyngeal angiofibroma of the cheek. J Laryngol Otol; 2006 Feb;120(2):141-4
MedlinePlus Health Information. consumer health - Oral Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extranasopharyngeal angiofibroma of the cheek.
  • Angiofibromas rarely localize in extranasopharyngeal sites.
  • The most common site for extranasopharyngeal angiofibromas is the maxillary sinus.
  • The ethmoid and sphenoid sinuses, nasal septum, middle and inferior turbinates, conjunctiva, molar and retromolar region, and larynx are other sites where extranasopharyngeal angiofibromas have been reported.
  • Only one case of buccal extranasopharyngeal angiofibroma has been reported to date.
  • We present a case of buccal extranasopharyngeal angiofibroma that was excised completely following embolization and we also review the literature.
  • [MeSH-major] Angiofibroma / pathology. Mouth Neoplasms / pathology. Vascular Neoplasms / pathology

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  • (PMID = 16359575.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 13
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74. Klockars T, Renkonen S, Leivo I, Hagström J, Mäkitie AA: Juvenile nasopharyngeal angiofibroma: no evidence for inheritance or association with familial adenomatous polyposis. Fam Cancer; 2010 Sep;9(3):401-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: no evidence for inheritance or association with familial adenomatous polyposis.
  • Juvenile nasopharyngeal angiofibromas (JNAs) are rare tumors with prominent vascularity and locally destructive growth.
  • Twenty-one patients diagnosed with juvenile angiofibroma filled out a detailed patient questionnaire.
  • No patients reported any relatives with nasopharyngeal angiofibroma or familial adenomatous polyposis.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Angiofibroma / genetics. Genetic Predisposition to Disease. Nasopharyngeal Neoplasms / genetics

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  • (PMID = 20229070.001).
  • [ISSN] 1573-7292
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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75. Chmielik LP, Frackiewicz M, Krajewski R, Woloszczuk-Gebicka B, Chmielik M: Perioperative problems and treatment of a teenager with a juvenile angiofibroma refusing blood transfusion. Int J Pediatr Otorhinolaryngol; 2009 May;73(5):689-92
MedlinePlus Health Information. consumer health - Nasal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Perioperative problems and treatment of a teenager with a juvenile angiofibroma refusing blood transfusion.
  • OBJECTIVES: Juvenile angiofibroma is a benign, non-encapsulated neoplasm, consisting of vascular and connective tissue.
  • Among theories about the aetiology of juvenile angiofibroma, we must consider a haematoma-like lesion, an angioma with an extended fibrous component, or type of inflammatory allergic polyp.
  • According to the latest research, juvenile angiofibroma is regarded as a developmental defect, affecting the embryonic vascular network surrounding the sphenoid bone.
  • Removal of juvenile angiofibroma with minimal bleeding is possible.
  • [MeSH-major] Angiofibroma / surgery. Blood Transfusion. Neoplasms, Connective Tissue / surgery. Nose Neoplasms / surgery. Postoperative Care. Preoperative Care. Treatment Refusal. Vascular Neoplasms / surgery

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  • (PMID = 19230984.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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76. Tosun F, Onerci M, Durmaz A, Ugurel S: Spontaneous involution of nasopharyngeal angiofibroma. J Craniofac Surg; 2008 Nov;19(6):1686-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous involution of nasopharyngeal angiofibroma.
  • There are several studies addressing regression of residual nasopharyngeal angiofibroma after surgery, but spontaneous regression of this tumor has been reported in only 2 cases.
  • We present a case of nasopharyngeal angiofibroma that has involuted spontaneously in the last 5 years.
  • This is the third reported case in the literature with spontaneous regression of nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 19098582.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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77. Coutinho-Camillo CM, Brentani MM, Nagai MA: Genetic alterations in juvenile nasopharyngeal angiofibromas. Head Neck; 2008 Mar;30(3):390-400

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic alterations in juvenile nasopharyngeal angiofibromas.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm of the nasopharynx that accounts for 0.5% of all head and neck tumors.
  • Although histologically benign in appearance, JNAs are locally aggressive and destructive, spreading from the nasal cavity to the nasopharynx, paranasal sinuses, and orbit skull base with intracranial extension.
  • [MeSH-major] Angiofibroma / genetics. Nasopharyngeal Neoplasms / genetics

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  • [Copyright] (c) 2008 Wiley Periodicals, Inc. Head Neck, 2008.
  • (PMID = 18228521.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Intercellular Signaling Peptides and Proteins; 0 / RNA, Messenger; 0 / Receptors, Steroid; 0 / beta Catenin; EC 2.5.1.18 / Glutathione Transferase
  • [Number-of-references] 103
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78. Jacyk WK, Rütten A, Requena L: Fibrous papule of the face with granular cells. Dermatology; 2008;216(1):56-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrous papule of the face with granular cells.
  • Fibrous papule of the face is a common benign lesion located most often on the nose.
  • It presents usually as a single small, firm, skin-coloured papule and is often misdiagnosed as melanocytic naevus, wart or small nodular basal cell carcinoma.
  • Uncommon histopathologic variants of fibrous papule of the face include hypercellular, clear-cell, pleomorphic, pigmented, inflammatory and granular-cell types.
  • We present here a patient with the syndrome of familial cancer and fibrous papule of the face with granular cells.
  • Probably the occurrence of the granular-cell fibrous papule of the face was coincidental.
  • [MeSH-major] Angiofibroma / pathology. Facial Neoplasms / pathology. Skin Neoplasms / pathology

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  • [Copyright] (c) 2008 S. Karger AG, Basel.
  • [CommentIn] Dermatology. 2008;217(1):56-7; author reply 57 [18382105.001]
  • (PMID = 18032900.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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79. Hodges JM, McDevitt AS, El-Sayed Ali AI, Sebelik ME: Juvenile nasopharyngeal angiofibroma: current treatment modalities and future considerations. Indian J Otolaryngol Head Neck Surg; 2010 Sep;62(3):236-47

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: current treatment modalities and future considerations.
  • Juvenile angiofibroma (JNA) is a relatively uncommon, highly vascular and benign tumor that presents most commonly in adolescent males.
  • With the advent of more sophisticated capabilities such as CT, MRI, intensity-modulated radiation therapy (IMRT), stereotactic guidance systems as well as advanced embolization techniques, these tumors can be diagnosed and managed more effectively.Patients with juvenile angiofibroma (JNA) are typically silent for years and often present with epistaxis, nasal obstruction, facial numbness, rhinorrhea, ear popping, sinusitis, cheek swelling, visual changes and headaches.
  • In addition to these symptoms, up to one-third of patients with this condition may present with proptosis or other orbital involvement, which are late symptoms and findings.Most physicians agree that surgery is the primary treatment modality for the early-stage disease process.
  • However, controversy arises regarding the best treatment when a patient presents with more locally advanced disease involving widespread cranial-based extension or intracranial involvement which may necessitate a combination of treatment modalities including surgery and postoperative radiation.With the advancement of endoscopic surgery, there have been a number of cases reporting the value of its use.

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  • (PMID = 23120720.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450247
  • [Keywords] NOTNLM ; Angiofibroma / Cyberknife / Embolization / Endoscopic surgery / IMRT / Image guided robotic radiotherapy / Skull base / Vascular tumor
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80. Cansiz H, Güvenç MG, Sekercioğlu N: Surgical approaches to juvenile nasopharyngeal angiofibroma. J Craniomaxillofac Surg; 2006 Jan;34(1):3-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical approaches to juvenile nasopharyngeal angiofibroma.
  • INTRODUCTION: Juvenile nasopharyngeal angiofibromas are highly vascular, non-encapsulated tumours affecting predominantly young males.
  • These lesions are benign histologically but they may become life-threatening with excessive bleeding or intracranial extension.
  • MATERIAL AND METHODS: The surgical approaches to 22 male patients with nasopharyngeal angiofibromas are reviewed.
  • CONCLUSION: The suggested treatment of juvenile nasopharyngeal angiofibroma consists of an endoscopic transnasal approach for early stage lesions, and a modified midfacial degloving for almost all of the advanced lesions.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Oral Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Carotid Artery Injuries / etiology. Carotid Artery, Internal / pathology. Child. Craniotomy / adverse effects. Endoscopy. Facial Paralysis / etiology. Frontal Bone / surgery. Humans. Male. Neoplasm Staging. Nose / surgery. Nose Diseases / etiology. Paresthesia / etiology. Postoperative Complications. Retrospective Studies. Rupture. Temporal Bone / surgery. Treatment Outcome

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  • (PMID = 16343920.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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81. Ahmad R, Ishlah W, Azilah N, Rahman JA: Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization. Asian J Surg; 2008 Oct;31(4):174-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm that occurs almost exclusively in the nasopharynx of adolescent males.

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  • (PMID = 19010758.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] China
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82. Li Z, Lin G, He L, Yi Z: [Perioperative managements of huge lobulated nasopharyngeal angiofibromas with intracranial extensions]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Jul;22(14):639-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Perioperative managements of huge lobulated nasopharyngeal angiofibromas with intracranial extensions].
  • OBJECTIVE: To summarize our experience of successful and failed management in 8 huge lobulated nasopharyngeal angiofibromas with intracranial extensions, and introduce some key points of perioperative treatments.
  • [MeSH-major] Angiofibroma / surgery. Brain Neoplasms / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18841793.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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83. Mohammadi M, Saedi B, Basam A: Effect of embolisation on endoscopic resection of angiofibroma. J Laryngol Otol; 2010 Jun;124(6):631-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of embolisation on endoscopic resection of angiofibroma.
  • OBJECTIVE: To determine the effect of embolisation on endoscopic resection of angiofibroma.
  • Twenty-three patients with angiofibroma (nine embolised and 14 not embolised) underwent endoscopic resection between January 2007 and August 2008 in two tertiary referral centres.
  • CONCLUSION: Endoscopic resection is a feasible and safe method for angiofibroma surgery.
  • The current evidence does not support obligatory embolisation in every case of endoscopic angiofibroma resection.
  • [MeSH-major] Angiofibroma / surgery. Blood Loss, Surgical / prevention & control. Embolization, Therapeutic. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 20067650.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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84. Hackman T, Snyderman CH, Carrau R, Vescan A, Kassam A: Juvenile nasopharyngeal angiofibroma: The expanded endonasal approach. Am J Rhinol Allergy; 2009 Jan-Feb;23(1):95-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: The expanded endonasal approach.
  • BACKGROUND: Juvenile nasopharyngeal angiofibroma (JNA) is a benign but locally aggressively vascular tumor that may involve the skull base and extend intracranially.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods

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  • (PMID = 19379621.001).
  • [ISSN] 1945-8924
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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85. Eloy P, Watelet JB, Hatert AS, de Wispelaere J, Bertrand B: Endonasal endoscopic resection of juvenile nasopharyngeal angiofibroma. Rhinology; 2007 Mar;45(1):24-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endonasal endoscopic resection of juvenile nasopharyngeal angiofibroma.
  • Juvenile angiofibroma (JNA) is a rare benign but locally aggressive tumour of the nasopharynx that primarily occurs in adolescent males.
  • According to Radkowski's classification (Table 1), one patient was stage Ia, one was stage Ib and four patients were stage IIb.
  • All patients but one were free of disease.
  • Based upon the recent international literature, endonasal surgery combined with a preoperative embolization of the arterial supply is indicated for small and middle size JNAs but also for large tumours extended to the pterygopalatine fossa and medial aspect of the infratemporal fossa.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 17432065.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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86. McAfee WJ, Morris CG, Amdur RJ, Werning JW, Mendenhall WM: Definitive radiotherapy for juvenile nasopharyngeal angiofibroma. Am J Clin Oncol; 2006 Apr;29(2):168-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Definitive radiotherapy for juvenile nasopharyngeal angiofibroma.
  • OBJECTIVES: To update our experience with definitive radiotherapy (RT) for juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma / radiotherapy. Nasopharyngeal Neoplasms / radiotherapy

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  • (PMID = 16601437.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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87. Saylam G, Yücel OT, Sungur A, Onerci M: Proliferation, angiogenesis and hormonal markers in juvenile nasopharyngeal angiofibroma. Int J Pediatr Otorhinolaryngol; 2006 Feb;70(2):227-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proliferation, angiogenesis and hormonal markers in juvenile nasopharyngeal angiofibroma.
  • OBJECTIVES: Juvenile nasopharyngeal angiofibroma (JNA) is a highly vascular and locally invasive tumor that exclusively affects male adolescents.
  • [MeSH-major] Angiofibroma / metabolism. Nasopharyngeal Neoplasms / metabolism. Neoplasm Recurrence, Local / metabolism

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  • (PMID = 16023739.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 0 / Transforming Growth Factor beta; 0 / Vascular Endothelial Growth Factor A
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88. Lehmann M, Ulrich S, Reineke U, Hamberger U, Dietrich U, Sudhoff H: [Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma]. HNO; 2010 Aug;58(8):853-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma].
  • Preoperative embolization for the treatment of juvenile nasopharyngeal angiofibroma was successfully accomplished with Onyx by intratumoral puncture for the first time.
  • Transnasal surgery on the following day achieved complete resection of the angiofibroma without complications.
  • Direct intratumoral embolization of juvenile nasopharyngeal angiofibromas appears to be a safe and effective preoperative method without complications.
  • [MeSH-major] Angiofibroma / blood supply. Angiofibroma / surgery. Dimethyl Sulfoxide. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / blood supply. Nasopharyngeal Neoplasms / surgery. Polyvinyls. Preoperative Care

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  • (PMID = 20596683.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Onyx copolymer; 0 / Polyvinyls; YOW8V9698H / Dimethyl Sulfoxide
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89. Heinrich UR, Brieger J, Gosepath J, Wierzbicka M, Sokolov M, Roth Y, Szyfter W, Bittinger F, Mann WJ: Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma. Cancer Genet Cytogenet; 2007 Jun;175(2):138-43

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor, mostly affecting adolescent males.
  • No DNA aneuploidy was detected, a finding in accordance with the generally benign characteristics of JNAs.
  • Autosomal gains in the primary tumor should be further evaluated as markers for a potentially increased risk of recurrence after surgical removal in this entity.
  • [MeSH-major] Angiofibroma / genetics. Chromosome Aberrations. Nasopharyngeal Neoplasms / genetics. Neoplasm Recurrence, Local / genetics

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  • (PMID = 17556070.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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90. de Brito Macedo Ferreira LM, Gomes EF, Azevedo JF, Souza JR, de Paula Araújo R, do Nascimento Rios AS: Endoscopic surgery of nasopharyngeal angiofibroma. Braz J Otorhinolaryngol; 2006 Jul-Aug;72(4):475-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic surgery of nasopharyngeal angiofibroma.
  • Nasopharyngeal angiofibroma is a vascular benign tumor that affects young men, and surgery is the treatment of choice.
  • Endoscopic surgery has been used to excise tumors in their initial stages, when there is no evidence of residual or recurrent disease.
  • AIM: The aim of this study is to evaluate the endoscopic approach preceded by tumor embolization as treatment option for stages II to III angiofibroma.
  • CONCLUSION: Based on the results, we may conclude that the endoscopic approach, when preceded by embolization, is effective to treat angiofibromas in their initial stages, with reduced postoperative morbidity.
  • [MeSH-major] Angiofibroma / therapy. Nasopharyngeal Neoplasms / therapy

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  • (PMID = 17143426.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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91. Huang J, Sacks R, Forer M: Endoscopic resection of juvenile nasopharyngeal angiofibroma. Ann Otol Rhinol Laryngol; 2009 Nov;118(11):764-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic resection of juvenile nasopharyngeal angiofibroma.
  • OBJECTIVES: A 2-surgeon technique has been proposed that allows resection of juvenile nasopharyngeal angiofibroma (JNA) with extension into the infratemporal fossa by utilizing a septal incision for passage of a retracting instrument from the opposite nostril.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 19999360.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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92. Solomon D, Isaacson G: Transoral "adenoidectomy" excision of juvenile nasopharyngeal angiofibromas. Ann Otol Rhinol Laryngol; 2007 Apr;116(4):243-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transoral "adenoidectomy" excision of juvenile nasopharyngeal angiofibromas.
  • OBJECTIVES: We describe a minimally invasive technique for excision of selected juvenile nasopharyngeal angiofibromas (JNAs) using indirect visualization of the nasopharynx.
  • The subjects included 4 teenage boys with early-stage nasopharyngeal angiofibromas.
  • All 4 boys are free of disease.
  • [MeSH-major] Adenoidectomy / methods. Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery
  • [MeSH-minor] Adolescent. Angiography. Disease-Free Survival. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Mouth. Neoplasm Staging. Retrospective Studies. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17491520.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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93. Ereño C, López JI, Pérez J, Grande J, Bilbao FJ: Orbital giant cell angiofibroma. APMIS; 2006 Sep;114(9):663-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital giant cell angiofibroma.
  • A case of giant cell angiofibroma in a 73-year-old man is reported.
  • The clinicopathological features of this rare neoplasm--that is nowadays considered a variant of solitary fibrous tumour--are reviewed and briefly commented on.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / pathology. Neoplasm Recurrence, Local / diagnosis. Neoplasms, Fibrous Tissue / diagnosis. Orbital Neoplasms / diagnosis

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  • (PMID = 16948822.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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94. Eze NN, Wyatt ME, Bray D, Bailey CM, Hartley BE: The midfacial degloving approach to sinonasal tumours in children. Rhinology; 2006 Mar;44(1):36-8
MedlinePlus Health Information. consumer health - Nasal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The procedure allows access to benign and malignant lesions of the sinonasal region with the avoidance of an external scar.
  • Eight children had benign pathology.
  • There were two juvenile angiofibromas, two nasal gliomas, one ossifying fibroma, one fibroma, one fibrous dysplasia and one benign myofibroblastic proliferation.
  • One child had malignant disease in the form of recurrent embryonal rhabdomyosarcoma.

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  • (PMID = 16550948.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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95. Koshy S, George M, Gupta A, Daniel RT: Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma. Indian J Dent Res; 2008 Oct-Dec;19(4):366-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare vascular neoplasm occurring almost exclusively in adolescent males.
  • Although benign, it is often locally aggressive and can erode into surrounding tissues and structures resulting in significant morbidity and mortality.
  • In this paper, we report on the total excision of a large, recurrent JNA with intracranial extension into the middle cranial fossa encroaching into the cavernous sinus, by right temporal craniotomy and extended osteoplastic maxillotomy.
  • [MeSH-major] Angiofibroma / surgery. Maxilla / surgery. Nasopharyngeal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Osteotomy / methods

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  • (PMID = 19075445.001).
  • [ISSN] 0970-9290
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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96. Nomura K, Shimomura A, Awataguchi T, Murakami K, Kobayashi T: A case of angiofibroma originating from the inferior nasal turbinate. Auris Nasus Larynx; 2006 Jun;33(2):191-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of angiofibroma originating from the inferior nasal turbinate.
  • Angiofibromas are nasopharyngeal tumors mostly seen in adolescent males.
  • Extranasopharyngeal angiofibromas, although rare, have been reported.
  • We report a case of extranasopharyngeal angiofibroma arising from the inferior turbinate of a 62-year-old male.
  • Previous extranasopharyngeal angiofibromas research was reviewed.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology. Turbinates / pathology

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  • (PMID = 16310998.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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97. Patrocínio JA, Patrocínio LG, Borba BH, Bonatti Bde S, Guimarães AH: Nasopharyngeal angiofibroma in an elderly woman. Am J Otolaryngol; 2005 May-Jun;26(3):198-200

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasopharyngeal angiofibroma in an elderly woman.
  • "Juvenile" nasopharyngeal angiofibroma is a locally aggressive, yet histologically benign, vascular neoplasm.
  • We report a rare case of a 64-year-old woman with a red lobulated mass in the right nostril, diagnosed as nasopharyngeal angiofibroma on postoperative histopathologic and immunohistochemical analysis.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 15858777.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Tsai CJ, Wang HM, Lu IC, Tai CF, Wang LF, Soo LY, Lu DV: Seizure after local anesthesia for nasopharyngeal angiofibroma. Kaohsiung J Med Sci; 2007 Feb;23(2):97-100
MedlinePlus Health Information. consumer health - Seizures.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Seizure after local anesthesia for nasopharyngeal angiofibroma.
  • We report a young male patient who experienced seizure after local injection of 3 mL 2% lidocaine with epinephrine 1:200,000 around a recurrent nasal angiofibroma.
  • [MeSH-major] Anesthesia, Local / adverse effects. Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Seizures / etiology

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  • (PMID = 17339174.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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99. Szymańska A, Korobowicz E, Gołabek W: A rare case of nasopharyngeal angiofibroma in an elderly female. Eur Arch Otorhinolaryngol; 2006 Jul;263(7):657-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of nasopharyngeal angiofibroma in an elderly female.
  • Nasopharyngeal angiofibromas occur predominantly in males in their puberty and adolescence; the incidence in other age groups and in women is exceptional.
  • This report describes a case of a 57-year-old woman with nasopharyngeal angiofibroma presenting typical radiological findings in computed tomography, MR imaging and angiography.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Nasopharyngeal Neoplasms / diagnosis. Nasopharyngeal Neoplasms / surgery
  • [MeSH-minor] Disease-Free Survival. Female. Follow-Up Studies. Humans. Magnetic Resonance Angiography. Middle Aged. Otorhinolaryngologic Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 16625398.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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100. Karthikeya P, Mahima VG, Bagewadi SB: Juvenile nasopharyngeal angiofibroma. Indian J Dent Res; 2005 Jan-Mar;16(1):22-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma.
  • Juvenile nasopharyngeal angiofibroma is a rare, histologically benign yet locally aggressive, vascular tumor that typically affects adolescent males.
  • A case of juvenile nasopharyngeal angiofibroma manifesting in the oral cavity in a 20-year-old male patient is presented and discussed.
  • [MeSH-major] Angiofibroma / diagnosis. Nasopharyngeal Neoplasms / diagnosis

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  • (PMID = 16375234.001).
  • [ISSN] 0970-9290
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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