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1. Li Z, Lin G, He L, Yi Z: [Perioperative managements of huge lobulated nasopharyngeal angiofibromas with intracranial extensions]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Jul;22(14):639-41
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  • [Title] [Perioperative managements of huge lobulated nasopharyngeal angiofibromas with intracranial extensions].
  • OBJECTIVE: To summarize our experience of successful and failed management in 8 huge lobulated nasopharyngeal angiofibromas with intracranial extensions, and introduce some key points of perioperative treatments.
  • [MeSH-major] Angiofibroma / surgery. Brain Neoplasms / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18841793.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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2. Konarev DV, Khasanov SS, Otsuka A, Saito G, Lyubovskaya RN: Negatively charged pi-(C60-)2 dimer with biradical state at room temperature. J Am Chem Soc; 2006 Jul 26;128(29):9292-3
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  • The behavior of spins in this dimer can be described by a model with a singlet ground state (S = 0) and a close lying excited triplet (S = 1) state with the energy gap of 2|JAF| = 70 +/- 2 cm-1.

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  • (PMID = 16848439.001).
  • [ISSN] 0002-7863
  • [Journal-full-title] Journal of the American Chemical Society
  • [ISO-abbreviation] J. Am. Chem. Soc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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3. Cansiz H, Güvenç MG, Sekercioğlu N: Surgical approaches to juvenile nasopharyngeal angiofibroma. J Craniomaxillofac Surg; 2006 Jan;34(1):3-8
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  • [Title] Surgical approaches to juvenile nasopharyngeal angiofibroma.
  • INTRODUCTION: Juvenile nasopharyngeal angiofibromas are highly vascular, non-encapsulated tumours affecting predominantly young males.
  • These lesions are benign histologically but they may become life-threatening with excessive bleeding or intracranial extension.
  • MATERIAL AND METHODS: The surgical approaches to 22 male patients with nasopharyngeal angiofibromas are reviewed.
  • CONCLUSION: The suggested treatment of juvenile nasopharyngeal angiofibroma consists of an endoscopic transnasal approach for early stage lesions, and a modified midfacial degloving for almost all of the advanced lesions.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Oral Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Carotid Artery Injuries / etiology. Carotid Artery, Internal / pathology. Child. Craniotomy / adverse effects. Endoscopy. Facial Paralysis / etiology. Frontal Bone / surgery. Humans. Male. Neoplasm Staging. Nose / surgery. Nose Diseases / etiology. Paresthesia / etiology. Postoperative Complications. Retrospective Studies. Rupture. Temporal Bone / surgery. Treatment Outcome

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  • (PMID = 16343920.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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4. Schuon R, Brieger J, Heinrich UR, Roth Y, Szyfter W, Mann WJ: Immunohistochemical analysis of growth mechanisms in juvenile nasopharyngeal angiofibroma. Eur Arch Otorhinolaryngol; 2007 Apr;264(4):389-94
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  • [Title] Immunohistochemical analysis of growth mechanisms in juvenile nasopharyngeal angiofibroma.
  • Angiogenic factors are discussed to participate in growth and promotion of juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma. Fibroblast Growth Factor 2 / immunology. Hypoxia-Inducible Factor 1, alpha Subunit / immunology. Lymphotoxin-alpha / immunology. Nasopharyngeal Neoplasms. Vascular Endothelial Growth Factor Receptor-1 / immunology. Vascular Endothelial Growth Factor Receptor-2 / immunology

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  • (PMID = 17177025.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Lymphotoxin-alpha; 103107-01-3 / Fibroblast Growth Factor 2; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-1; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2
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5. Zoumalan CI, Egbert PR, Warwar RE, McCulley TJ: Orbital giant cell angiofibroma recurring as a solitary fibrous tumor. Ophthal Plast Reconstr Surg; 2008 Jul-Aug;24(4):325-7
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  • [Title] Orbital giant cell angiofibroma recurring as a solitary fibrous tumor.
  • Giant cell angiofibroma has recently been hypothesized to be a clinicopathologic variant of solitary fibrous tumor.
  • The authors report a case of an orbital giant cell angiofibroma that recurred as a solitary fibrous tumor 4 years later.
  • The report strongly supports the hypothesis that giant cell angiofibroma and solitary fibrous tumor are related.
  • [MeSH-major] Angiofibroma / pathology. Giant Cells / pathology. Neoplasm Recurrence, Local / pathology. Orbital Neoplasms / pathology. Solitary Fibrous Tumors / pathology

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  • (PMID = 18645449.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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6. Mondal P, Basu N, Gupta SS, Bhattacharya N, Mallick MG: Fine needle aspiration cytology of parapharyngeal tumors. J Cytol; 2009 Jul;26(3):102-4
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  • The tumors encountered were, pleomorphic adenoma (33), schwannoma (3), neurofibroma (11), paraganglioma (5), angiofibroma (1) and adenoid cystic carcinoma (1).

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  • (PMID = 21938166.001).
  • [ISSN] 0970-9371
  • [Journal-full-title] Journal of cytology
  • [ISO-abbreviation] J Cytol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3168009
  • [Keywords] NOTNLM ; Parapharyngeal space tumors / fine needle aspiration cytology / paraganglioma
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7. Sciarretta V, Pasquini E, Frank G, Modugno GC, Cantaroni C, Mazzatenta D, Farneti G: Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases. Am J Rhinol; 2006 Jan-Feb;20(1):64-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases.
  • BACKGROUND: The endoscopic approach can be used successfully for the treatment of benign tumors such as fibroosseous and vascular lesions, pleomorphic adenoma, glioma, meningioma, and schwannoma.
  • METHODS: Thirty-three patients diagnosed with benign tumors of the nasal cavity and paranasal sinuses and treated using an endoscopic approach were reviewed retrospectively.
  • The mean follow-up was 28 months and only two recurrences (6%) were observed in the juvenile angiofibroma group and in the case of the fibrous dysplasia associated to aneurysmal bone cyst, respectively, 20 and 24 months postoperatively.
  • CONCLUSION: In selected cases, endoscopic surgery can be considered an effective treatment for the resection of benign tumors involving the sinonasal tract.
  • [MeSH-minor] Adolescent. Adult. Aged. Angiofibroma / surgery. Child. Child, Preschool. Female. Follow-Up Studies. Glioma / surgery. Hemangioma, Cavernous / surgery. Humans. Magnetic Resonance Imaging. Male. Meningioma / surgery. Middle Aged. Osteoma / surgery. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16539297.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Perez EG, Paranaíba LR, Bonan PR, Orsi Júnior JM, Oliveira AM, Martelli Júnior H: [Tuberous sclerosis: evaluation of myofibroblasts in cutaneous angiofibromas - case report]. An Bras Dermatol; 2010 Jan-Feb;85(1):84-8
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  • [Title] [Tuberous sclerosis: evaluation of myofibroblasts in cutaneous angiofibromas - case report].
  • [Transliterated title] Esclerose tuberosa: avaliação de miofibroblastos em angiofibromas cutâneos - relato de caso.
  • Tuberous sclerosis is a rare autosomal dominant disorder.
  • The objective of this study is to describe clinical and histopathological characteristics of tuberous sclerosis and to conduct an immunohistochemical evaluation of myofibroblasts in cutaneous angiofibromas present in this condition.
  • Since alpha-SMA is a specific marker for myofibroblasts, this result suggests that myofibroblasts are not involved in cutaneous angiofibromas present in the tuberous sclerosis case reported.
  • [MeSH-major] Angiofibroma / complications. Angiofibroma / pathology. Fibroblasts / pathology. Skin Neoplasms / complications. Skin Neoplasms / pathology. Tuberous Sclerosis / complications


9. Kandil DH, Kida M, Laub DR, Cooper K: Sarcomatous transformation in a cellular angiofibroma: a case report. J Clin Pathol; 2009 Oct;62(10):945-7
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  • [Title] Sarcomatous transformation in a cellular angiofibroma: a case report.
  • Cellular angiofibroma is a rare benign mesenchymal tumour of middle-aged adults.
  • This report describes the case of a patient with a 3.5 cm subcutaneous mass, 2 cm below the left anterior superior iliac spine.
  • This is believed to be the first reported case of sarcomatous transformation in a cellular angiofibroma.
  • [MeSH-major] Angiofibroma / pathology. Sarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Disease Progression. Fatal Outcome. Humans. Neoplasms, Second Primary

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  • (PMID = 19783726.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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10. Hoff AO, Hauache OM: [Multiple endocrine neoplasia type 1 (MEN 1): clinical, biochemical and molecular diagnosis and treatment of the associated disturbances]. Arq Bras Endocrinol Metabol; 2005 Oct;49(5):735-46
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  • In addition, these patients can present with cutaneous manifestations such as angiofibromas and collagenomas, and can develop other neoplastic manifestations including carcinoids, thyroid tumors, adrenal adenomas, lipomas, pheochromocytomas and meningiomas.


11. Erkan AN, Tarhan E, Yilmazer C, Cağici A, Cakmak O: [Endoscopic removal of sinonasal tumors]. Kulak Burun Bogaz Ihtis Derg; 2006;16(2):72-9
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  • RESULTS: There were five osteomas, one fibrous dysplasia, one ossifying fibroma, seven inverted papillomas, one oncocytic papilloma, three angiofibromas, one schwannoma, and one esthesioneuroblastoma.
  • The fibrous dysplasia involving the posterior ethmoid sinuses was subtotally resected due to its close proximity to the optic nerve.
  • [MeSH-minor] Adolescent. Adult. Child. Endoscopy / utilization. Female. Fibroma / epidemiology. Fibroma / etiology. Fibroma / pathology. Fibroma / surgery. Humans. Male. Medical Records. Middle Aged. Neurilemmoma / epidemiology. Neurilemmoma / etiology. Neurilemmoma / pathology. Neurilemmoma / surgery. Osteoma / epidemiology. Osteoma / etiology. Osteoma / pathology. Osteoma / surgery. Papilloma / epidemiology. Papilloma / etiology. Papilloma / pathology. Papilloma / surgery. Retrospective Studies. Turkey / epidemiology

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  • (PMID = 16763420.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Turkey
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12. Schick B, Veldung B, Wemmert S, Jung V, Montenarh M, Meese E, Urbschat S: p53 and Her-2/neu in juvenile angiofibromas. Oncol Rep; 2005 Mar;13(3):453-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p53 and Her-2/neu in juvenile angiofibromas.
  • The pathogenesis of juvenile angiofibroma (JA) remains unsolved.
  • [MeSH-major] Angiofibroma / genetics. Angiofibroma / physiopathology. Chromosomes, Human, Pair 17. Gene Expression Profiling. Receptor, ErbB-2 / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis

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  • (PMID = 15706416.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / Tumor Suppressor Protein p53; EC 2.7.10.1 / Receptor, ErbB-2
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13. Deviprasad S, Rajeshwari A, Tahir M, Adarsha TV, Gangadhara S: Small-cell neuroendocrine carcinoma originating from the lateral nasopharyngeal wall. Ear Nose Throat J; 2008 Nov;87(11):E1-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Initial biopsy was suggestive of angiofibroma.

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  • (PMID = 19006052.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Ferreira S, Nogueira C, Ferreira D, Neves S, Taveira N: [Tuberous sclerosis with pulmonary involvment]. Rev Port Pneumol; 2010 Mar-Apr;16(2):339-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tuberous sclerosis (TS) is a rare, sporadic or autosomal dominant disease characterized by the triad of seizures, mental retardation and angiofibromas.
  • We report the case of a 52 year -old female, nonsmoker, with a history of seizures in childhood and renal angiomyolipomas.
  • Chest CT performed for the evaluation of the disease detected thin-walled pulmonary cysts in both lungs.
  • [MeSH-major] Lung Diseases / etiology. Tuberous Sclerosis / complications

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  • (PMID = 20437010.001).
  • [ISSN] 2172-6825
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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15. Nicolai P, Villaret AB, Farina D, Nadeau S, Yakirevitch A, Berlucchi M, Galtelli C: Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases. Am J Rhinol Allergy; 2010 Mar-Apr;24(2):e67-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases.
  • BACKGROUND: At present, transnasal endoscopic surgery is considered a viable option in the management of small-intermediate size juvenile angiofibromas (JAs).
  • The lesions were classified according to Andrews (Andrews JC, et al., The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach, Laryngoscope 99:429-437, 1989) and Onerci (Onerci M, et al.
  • Juvenile nasopharyngeal angiofibroma: A revised staging system, Rhinology 44:39-45, 2006) staging systems.
  • RESULTS: Lesions were classified as follows: stage I, n = 5; stage II, n = 24; stage IIIa, n = 14; stage IIIb, n = 3 according to Andrews classification system; stage 1, n = 9; stage II, n = 12; stage III, n = 26 according to Onerci's system.
  • In four (8.7%) cases, suspicious residual disease was detected by MRI.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nose Neoplasms / surgery

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  • (PMID = 20338105.001).
  • [ISSN] 1945-8932
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Szymańska A, Szymański M, Skomra D, Szczerbo-Trojanowska M: Extranasopharyngeal angiofibroma of the infratemporal fossa. Otolaryngol Head Neck Surg; 2009 Mar;140(3):433-434
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extranasopharyngeal angiofibroma of the infratemporal fossa.
  • [MeSH-major] Angiofibroma / pathology. Cranial Fossa, Middle / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 19248960.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Ahmad R, Ishlah W, Azilah N, Rahman JA: Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization. Asian J Surg; 2008 Oct;31(4):174-8
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  • [Title] Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm that occurs almost exclusively in the nasopharynx of adolescent males.

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  • (PMID = 19010758.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] China
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18. Giavroglou C, Constantinidis J, Triaridis S, Daniilidis J, Dimitriadis A: [Angiographic evaluation and embolization of juvenile nasopharyngeal angiofibroma]. HNO; 2007 Jan;55(1):36-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiographic evaluation and embolization of juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Juveniles Angiofibrom: Angiographische Diagnostik und präoperative Embolisation.
  • OBJECTIVE: In juvenile nasopharyngeal angiofibroma (JNA), analysis of tumor extension and blood supply is useful for controlling intraoperative bleeding and helps in determining the appropriate surgical approach.
  • [MeSH-major] Angiofibroma / diagnostic imaging. Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / diagnostic imaging. Nasopharyngeal Neoplasms / therapy. Neoplasm Recurrence, Local / prevention & control

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  • [Cites] Eur Radiol. 1998;8(5):756-64 [9601961.001]
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  • (PMID = 16775738.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
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19. Lin C, Li ZC, Cheng JM, Lin GB, Zhou AD, Yi ZX: [Pathological features and clinical managements of nasopharyngeal angiofibroma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Oct;43(10):763-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pathological features and clinical managements of nasopharyngeal angiofibroma].
  • OBJECTIVE: To study the pathological features of nasopharyngeal angiofibroma (NA) and the principles for clinical managements.
  • The tumor extensions such as in pterygopalatine fossa and infratemporal fossa were covered by fibrous pseudocapsule.
  • CONCLUSIONS: nasopharyngeal angiofibroma is covered by epithelium or pseudo-capsule, it does not infiltrate the surrounding tissue.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 19119673.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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20. Sinha V, Ninama M, Prajapati B, Gupta D, More Y, Bhat V, Singh SN: Juvenile nasopharyngeal angiofibroma-our experience at a referral hospital. Indian J Otolaryngol Head Neck Surg; 2009 Jan;61(Suppl 1):17-21
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  • [Title] Juvenile nasopharyngeal angiofibroma-our experience at a referral hospital.
  • Nasopharyngeal angiofibroma is a rare, highly vascular locally invasive tumor with a strong tendency to bleed.
  • This is a retrospective study of 53 patients with nasopharyngeal angiofibroma.
  • Three out of four patients with recurrence had to undergo repeat surgery for the removal of angiofibroma within six months while the remaining one was referred to radiotherapy as the mass was invading the cavernous sinus.

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  • (PMID = 23120663.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450092
  • [Keywords] NOTNLM ; Juvenile nasopharyngeal angiofibroma / Transpalatal approach
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21. Cherekaev VA, Belov AI, Kulikovskiĭ PV, Arustamian SR: [Juvenile angiofibroma predominantly extending into the middle cranial fossa and eye-socket]. Zh Vopr Neirokhir Im N N Burdenko; 2006 Jan-Mar;(1):37-9; discussion 39-40
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  • [Title] [Juvenile angiofibroma predominantly extending into the middle cranial fossa and eye-socket].
  • The paper analyzes a rare case of juvenile angiofibroma primarily locating in the infratemporal and middle cranial fossa without a nodule in the nasopharynx.
  • Since the disease has started from right facial hypesthesia, neurinoma involving the first and second branches of the trigeminal nerve and spreading to the eye-socket may be suggested.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Skull Base Neoplasms / diagnosis. Skull Base Neoplasms / surgery

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  • (PMID = 16739934.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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22. Padilla Parrado M, Díaz Sastre MA, Jiménez Antolín JA, Caro García MA: [Juvenile nasopharyngeal angiofibroma]. An Otorrinolaringol Ibero Am; 2005;32(4):361-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Angiofibroma nasofaringeo juvenil. Situación actual.
  • Juvenile Juvenile nasopharyngeal angiofibroma (JNA) is a benign and highly vascular tumor.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 16156366.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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23. Santaolalla F, Araluce I, Zabala A, López A, Garay M, Sanchez JM: Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA). Acta Otolaryngol; 2009 Dec;129(12):1456-62
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  • [Title] Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA).
  • CONCLUSION: Percutaneous embolization reduces the reappearance of epistaxis and the mean length of hospital stay for patients with intractable epistaxis or juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic. Epistaxis / therapy. Nasopharyngeal Neoplasms / therapy

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  • (PMID = 19922097.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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24. Harvey RJ, Sheehan PO, Debnath NI, Schlosser RJ: Transseptal approach for extended endoscopic resections of the maxilla and infratemporal fossa. Am J Rhinol Allergy; 2009 Jul-Aug;23(4):426-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Preoperative assessment of skull base tumor, papilloma and angiofibroma extent, and resection margin will dictate surgical approach.
  • [MeSH-major] Cranial Fossa, Posterior / surgery. Endoscopy / methods. Maxilla / pathology. Maxillary Diseases / surgery. Nasal Septum / surgery. Temporal Bone / surgery

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  • (PMID = 19671261.001).
  • [ISSN] 1945-8924
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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25. Grieb S, Kruse R, Bruch-Gerharz D, Reifenberger J: [Tuberous sclerosis: diagnostic criteria and new treatment approaches]. Hautarzt; 2008 Oct;59(10):774-6
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  • Treatment for many years consisted solely in using nonspecific symptomatic approaches; dermatological therapy comprised mainly laser or electroacoustic ablation of facial angiofibromas.
  • [MeSH-major] Dermatologic Agents / therapeutic use. Interferon-gamma / therapeutic use. Skin Diseases / diagnosis. Skin Diseases / drug therapy. Tuberous Sclerosis / diagnosis. Tuberous Sclerosis / drug therapy


26. Hall MR, Kovach BT, Miller JL: Unilateral facial angiofibromas without other evidence of tuberous sclerosis: case report and review of the literature. Cutis; 2007 Oct;80(4):284-8
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  • [Title] Unilateral facial angiofibromas without other evidence of tuberous sclerosis: case report and review of the literature.
  • Bilateral facial angiofibromas are common cutaneous manifestations of tuberous sclerosis, an autosomal-dominant disease characterized by hamartomas of multiple organs.
  • We present a 28-year-old man with unilateral facial angiofibromas, which may represent a segmental form of tuberous sclerosis.
  • [MeSH-major] Angiofibroma / pathology. Facial Neoplasms / pathology. Skin Neoplasms / pathology. Tuberous Sclerosis / pathology

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  • [ErratumIn] Cutis. 2008 Feb;81(2):155
  • (PMID = 18038689.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 25
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27. Vidal A, Iglesias MJ, Fernández B, Fonseca E, Cordido F: Cutaneous lesions associated to multiple endocrine neoplasia syndrome type 1. J Eur Acad Dermatol Venereol; 2008 Jul;22(7):835-8
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  • BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is a genetic disease that predisposes to endocrine tumour development.
  • Some cutaneous lesions (angiofibromas, collagenomas, melanosis guttaca, lipomas, melanomas, 'cafe au lait macules') have been associated to this syndrome.
  • The frequency of angiofibromas was lower (22.2%) than the reported in other studies (43-88%), and we did not find any collagenoma.
  • [MeSH-major] Angiofibroma / epidemiology. Lipoma / epidemiology. Multiple Endocrine Neoplasia Type 1 / epidemiology. Proto-Oncogene Proteins / genetics. Skin Neoplasms / epidemiology
  • [MeSH-minor] Adenoma / epidemiology. Adenoma / genetics. Adult. Female. Genetic Predisposition to Disease / epidemiology. Genetic Testing. Humans. Hyperparathyroidism / epidemiology. Hyperparathyroidism / genetics. Male. Middle Aged. Pancreatic Neoplasms / epidemiology. Pancreatic Neoplasms / genetics. Pituitary Neoplasms / epidemiology. Pituitary Neoplasms / genetics. Prevalence


28. Hassan S, Abdullah J, Abdullah B, Jihan Wd S, Jaafar H, Abdullah S: Appraisal of clinical profile and management of juvenile nasopharyngeal angiofibroma in malaysia. Malays J Med Sci; 2007 Jan;14(1):18-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appraisal of clinical profile and management of juvenile nasopharyngeal angiofibroma in malaysia.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a benign but locally invasive tumour.

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  • (PMID = 22593647.001).
  • [ISSN] 1394-195X
  • [Journal-full-title] The Malaysian journal of medical sciences : MJMS
  • [ISO-abbreviation] Malays J Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
  • [Other-IDs] NLM/ PMC3351213
  • [Keywords] NOTNLM ; Juvenile nasopharyngeal angiofibroma / clinical profile / diagnosis / maxillary swing / surgical options
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29. Klockars T, Renkonen S, Leivo I, Hagström J, Mäkitie AA: Juvenile nasopharyngeal angiofibroma: no evidence for inheritance or association with familial adenomatous polyposis. Fam Cancer; 2010 Sep;9(3):401-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: no evidence for inheritance or association with familial adenomatous polyposis.
  • Juvenile nasopharyngeal angiofibromas (JNAs) are rare tumors with prominent vascularity and locally destructive growth.
  • Twenty-one patients diagnosed with juvenile angiofibroma filled out a detailed patient questionnaire.
  • No patients reported any relatives with nasopharyngeal angiofibroma or familial adenomatous polyposis.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Angiofibroma / genetics. Genetic Predisposition to Disease. Nasopharyngeal Neoplasms / genetics

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  • (PMID = 20229070.001).
  • [ISSN] 1573-7292
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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30. Haq MZ, Dubey I, Khess CR, Das U, Kumar R: Bipolar disorder and tuberous sclerosis complex: is it a mere coincidence? CNS Spectr; 2009 Nov;14(11):643-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bipolar disorder and tuberous sclerosis complex: is it a mere coincidence?
  • There are very few reports of bipolar disorder in TSC.
  • The authors present the case of a patient with TSC having bipolar disorder manifesting as manic as well as depressive episodes.
  • The diagnosis of TSC was based on the presence of facial angiofibromas, enamel pits, and shagreen patches on clinical examination, and the presence of cortical tubers and calcified subependymal nodules on neuroimaging.
  • To our knowledge, this is the first report of TSC with bipolar disorder having both manic as well as depressive episodes.
  • The nature of association between TSC and bipolar disorder, and its clinical implications are discussed.
  • [MeSH-major] Bipolar Disorder / etiology. Tuberous Sclerosis / complications


31. González-Pérez LM, Sánchez-Gallego F, Haro-Luna JJ, Infante-Cossío P: Giant cell angiofibroma of parapharyngeal space: a report of a new location for a rare tumour. Int J Oral Maxillofac Surg; 2010 Oct;39(10):1024-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant cell angiofibroma of parapharyngeal space: a report of a new location for a rare tumour.
  • Giant cell angiofibroma was first described as a distinctive orbital soft-tissue tumour in male adults; it is now recognized that this mesenchymal tumour can present in other anatomical regions.
  • In this article, a case of giant cell angiofibroma of parapharyngeal space in a 25-year-old woman is described.
  • To the authors' knowledge, this is the first reported case of giant cell angiofibroma arising in the parapharyngeal space.
  • [MeSH-major] Angiofibroma / diagnosis. Parotid Neoplasms / diagnosis. Pharyngeal Neoplasms / diagnosis

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  • [Copyright] Copyright © 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20537864.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Vimentin
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32. Kau R, Tanna M, Misra S, Contreras AL: Nasopharyngeal angiofibroma. Ear Nose Throat J; 2008 May;87(5):256
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 18572778.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vimentin
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33. Gil Z, Constantini S, Spektor S, Abergel A, Khafif A, Beni-Adani L, Leonor TL, DeRowe A, Fliss DM: Skull base approaches in the pediatric population. Head Neck; 2005 Aug;27(8):682-9
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  • Eighteen cases (27%) involved malignant tumors, and 49 (73%) involved benign tumors.
  • The most common benign tumors were craniopharyngioma (n = 10) and juvenile nasopharyngeal angiofibroma (n = 8).
  • Five children, two with optic glioma and one each with squamous cell carcinoma, ependymoma, and germinoma, have died of their disease.

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  • [Copyright] Copyright 2005 Wiley Periodicals, Inc.
  • (PMID = 15957193.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Pantelis A, Bootz F, Kühnel T: [Laser skin resurfacing and fibrin sealing as successful treatment for facial angiofibromas in tuberous sclerosis]. HNO; 2007 Dec;55(13):1009-11
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  • [Title] [Laser skin resurfacing and fibrin sealing as successful treatment for facial angiofibromas in tuberous sclerosis].
  • Paranasal angiofibromas may cause bleeding and difficulties in nasal breathing and can stigmatise the individual.
  • [MeSH-major] Angiofibroma / therapy. Debridement / methods. Fibrin Tissue Adhesive / therapeutic use. Laser Therapy / methods. Reconstructive Surgical Procedures / methods. Skin Neoplasms / therapy. Tuberous Sclerosis / therapy


35. Song A, Syed N, Kirby PA, Carter KD: Giant cell angiofibroma of the ocular adnexae. Arch Ophthalmol; 2005 Oct;123(10):1438-43
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  • [Title] Giant cell angiofibroma of the ocular adnexae.
  • [MeSH-major] Angiofibroma / pathology. Conjunctival Neoplasms / pathology. Giant Cell Tumors / pathology

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  • (PMID = 16219740.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Vimentin
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36. Vasudevan B, Sawhney MP, Radhakrishnan S, Shilpa G: Tuberous sclerosis with portal vein thrombosis, protein C and S deficiency. Indian J Dermatol Venereol Leprol; 2007 Nov-Dec;73(6):412-4
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  • On examination, angiofibromas on face, shagreen patch and periungual fibromas were observed.
  • [MeSH-minor] Adult. Angiofibroma / complications. Brain Diseases / complications. Dental Fissures / complications. Facial Neoplasms / complications. Female. Fibroma / complications. Hamartoma / complications. Humans. Kidney Diseases / complications. Retinal Diseases / complications


37. Schlauder SM, Knapp C, Steffensen TS, Bui MM: Aromatase may play a critical role in the pathogenesis of juvenile nasopharyngeal angiofibroma. Fetal Pediatr Pathol; 2009;28(5):232-8
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  • [Title] Aromatase may play a critical role in the pathogenesis of juvenile nasopharyngeal angiofibroma.
  • The pathophysiology of juvenile nasopharyngeal angiofibroma (JNA) has yet to be fully elucidated, but the influence of steroid hormones in their growth has been suggested.
  • [MeSH-major] Angiofibroma / pathology. Aromatase / metabolism. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 19842877.001).
  • [ISSN] 1551-3823
  • [Journal-full-title] Fetal and pediatric pathology
  • [ISO-abbreviation] Fetal Pediatr Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Androgens; 0 / Receptors, Androgen; 0 / Receptors, Estrogen; EC 1.14.14.1 / Aromatase
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38. Mistry RC, Qureshi SS, Gupta S, Gupta S: Juvenile nasopharyngeal angiofibroma: a single institution study. Indian J Cancer; 2005 Jan-Mar;42(1):35-9
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  • [Title] Juvenile nasopharyngeal angiofibroma: a single institution study.
  • BACKGROUND: Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor of adolescent males and there is a paucity of Indian studies on this subject.
  • The age distribution, disease patterns, management approaches and treatment outcomes of patients in the two groups were recorded.
  • RESULTS: The mean age at presentation was 16 years and more than 90% of the patients had Stage III or IV disease.
  • Aggressive re-resection should be done for resectable recurrences reserving radiotherapy for unresectable, recurrent/ residual disease.
  • [MeSH-major] Angiofibroma / epidemiology. Nasopharyngeal Neoplasms / epidemiology. Neoplasm Recurrence, Local / epidemiology

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  • (PMID = 15805690.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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39. Gemmete JJ, Ansari SA, McHugh J, Gandhi D: Embolization of vascular tumors of the head and neck. Neuroimaging Clin N Am; 2009 May;19(2):181-98, Table of Contents
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  • Juvenile nasopharyngeal angiofibromas and paragangliomas are the most common hypervascular tumors of the head and neck that require embolization as an adjunct to surgery.

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  • (PMID = 19442905.001).
  • [ISSN] 1557-9867
  • [Journal-full-title] Neuroimaging clinics of North America
  • [ISO-abbreviation] Neuroimaging Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 80
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40. Krupashankar DS, IADVL Dermatosurgery Task Force: Standard guidelines of care: CO2 laser for removal of benign skin lesions and resurfacing. Indian J Dermatol Venereol Leprol; 2008 Jan;74 Suppl:S61-7
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  • [Title] Standard guidelines of care: CO2 laser for removal of benign skin lesions and resurfacing.
  • INDICATIONS FOR CO 2 LASER: Therapeutic indications: Actinic and seborrheic keratosis, warts, moles, skin tags, epidermal and dermal nevi, vitiligo blister and punch grafting, rhinophyma, sebaceous hyperplasia, xanthelasma, syringomas, actinic cheilitis angiofibroma, scar treatment, keloid, skin cancer, neurofibroma and diffuse actinic keratoses.
  • For the use of CO 2 lasers for benign growths, a full day workshop is adequate.

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  • (PMID = 18688106.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Journal Article; Practice Guideline
  • [Publication-country] India
  • [Investigator] Mysore V; Sanant S; Khunger N; Patwardhan N; Prasad D; Buddhadev R; Chatterjee M; Gupta S; Shetty MK; Krupashankar DS; Rao KH; Vedamurthy M; Oberai C; Lahiri K; Sachidanand S; Joshipura S
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41. Nuzzo V, Tauchmanová L, Falchetti A, Faggiano A, Marini F, Piantadosi S, Brandi ML, Leopaldi L, Colao A: MEN1 family with a novel frameshift mutation. J Endocrinol Invest; 2006 May;29(5):450-6
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  • The proband, a Caucasian man, was admitted to our department in 2001, at the age of 51 because of a 1-yr history of diarrhoea and hypertension.
  • He had also undergone a left adrenalectomy for a large nonfunctioning adrenal adenoma.
  • On physical examination, multiple abdominal cutaneous lipomas and facial angiofibromas were observed.
  • The whole body computed tomography (CT) scan, the 111In-octreotide scan and the pituitary magnetic resonance imaging (MRI) did not reveal any abnormality.

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42. Krueger DA, Franz DN: Current management of tuberous sclerosis complex. Paediatr Drugs; 2008;10(5):299-313
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  • Tuberous sclerosis complex (TSC) is an important cause of epilepsy, autism, and renal and pulmonary disease in children and adults.
  • The clinical course of TSC and the prognosis and appropriate therapy for TSC patients are often different than that for individuals with epilepsy, renal tumors, or interstitial lung disease from other causes.
  • In addition, recent clinical trials using inhibitors of the mammalian target of rapamycin (mTOR) have demonstrated regression of astrocytomas, angiofibromas, and angiomyoliomas, as well as improved pulmonary function in persons with TSC.
  • [MeSH-minor] Antibiotics, Antineoplastic / therapeutic use. Child. Humans. Kidney Diseases / drug therapy. Kidney Diseases / etiology. Lung Diseases / drug therapy. Lung Diseases / etiology. Nervous System Diseases / drug therapy. Nervous System Diseases / etiology. Sirolimus / therapeutic use

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  • (PMID = 18754697.001).
  • [ISSN] 1174-5878
  • [Journal-full-title] Paediatric drugs
  • [ISO-abbreviation] Paediatr Drugs
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; W36ZG6FT64 / Sirolimus
  • [Number-of-references] 123
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43. Shcherbenko OI, Rodionov MV, Lebedev VA, Kliachkina NB: [Efficacy of remote gamma-therapy in patients with juvenile angiofibroma of the base of the skull]. Vestn Otorinolaringol; 2008;(3):26-8
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  • [Title] [Efficacy of remote gamma-therapy in patients with juvenile angiofibroma of the base of the skull].
  • The results of radiation therapy of 48 patients with juvenile nasopharyngeal angiofibroma were analysed.
  • [MeSH-major] Angiofibroma / radiotherapy. Gamma Rays / therapeutic use. Skull Base Neoplasms / radiotherapy

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  • (PMID = 18833092.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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44. Hatem R, Lamia T, Raouf C, Azza S, Karima Z, Nadia E, Najla M, Radhi H: [Embolization of head and neck hypervascular lesions. A retrospective study of 5 cases]. Tunis Med; 2005 Oct;83(10):627-30
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  • [Transliterated title] Embolisation des lesions hypervasculaires de la face et du cou. Etude rétrospective à propos de 5 cas.
  • Lesions were distributed as follow: nasal angiofibroma (n = I), nasal angioleiomyoma (n = I), nasopharyngeal angiofibroma (n = I), aneurysmal bone cyst in the posterior element of the second cervical vertebra (n = I) and AVM of the inferior lip (n = I).

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  • (PMID = 16370215.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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45. Jacyk WK, Rütten A, Requena L: Fibrous papule of the face with granular cells. Dermatology; 2008;216(1):56-9
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  • [Title] Fibrous papule of the face with granular cells.
  • Fibrous papule of the face is a common benign lesion located most often on the nose.
  • It presents usually as a single small, firm, skin-coloured papule and is often misdiagnosed as melanocytic naevus, wart or small nodular basal cell carcinoma.
  • Uncommon histopathologic variants of fibrous papule of the face include hypercellular, clear-cell, pleomorphic, pigmented, inflammatory and granular-cell types.
  • We present here a patient with the syndrome of familial cancer and fibrous papule of the face with granular cells.
  • Probably the occurrence of the granular-cell fibrous papule of the face was coincidental.
  • [MeSH-major] Angiofibroma / pathology. Facial Neoplasms / pathology. Skin Neoplasms / pathology

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  • [Copyright] (c) 2008 S. Karger AG, Basel.
  • [CommentIn] Dermatology. 2008;217(1):56-7; author reply 57 [18382105.001]
  • (PMID = 18032900.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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46. Ereño C, López JI, Pérez J, Grande J, Bilbao FJ: Orbital giant cell angiofibroma. APMIS; 2006 Sep;114(9):663-5
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  • [Title] Orbital giant cell angiofibroma.
  • A case of giant cell angiofibroma in a 73-year-old man is reported.
  • The clinicopathological features of this rare neoplasm--that is nowadays considered a variant of solitary fibrous tumour--are reviewed and briefly commented on.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / pathology. Neoplasm Recurrence, Local / diagnosis. Neoplasms, Fibrous Tissue / diagnosis. Orbital Neoplasms / diagnosis

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  • (PMID = 16948822.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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47. Montag AG, Tretiakova M, Richardson M: Steroid hormone receptor expression in nasopharyngeal angiofibromas. Consistent expression of estrogen receptor beta. Am J Clin Pathol; 2006 Jun;125(6):832-7
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  • [Title] Steroid hormone receptor expression in nasopharyngeal angiofibromas. Consistent expression of estrogen receptor beta.
  • Nasopharyngeal angiofibroma is an uncommon tumor arising in adolescent males, suggesting that the tumor may be hormonally responsive.
  • The recently described ss receptor for estrogen has not been analyzed in angiofibroma.
  • We analyzed 13 cases of nasal angiofibroma by immunohistochemical analysis for the presence of ARs, progesterone receptors (PR), and ER-a and ER-ss.
  • The findings confirm that nasopharyngeal angiofibromas express ER and suggest that new modulators of ER-ss activity may provide an alternative therapy for these lesions.
  • [MeSH-major] Angiofibroma / metabolism. Estrogen Receptor beta / metabolism. Nasopharyngeal Neoplasms / metabolism. Receptors, Androgen / metabolism. Receptors, Progesterone / metabolism

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  • (PMID = 16690481.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Estrogen Receptor beta; 0 / Receptors, Androgen; 0 / Receptors, Progesterone
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48. Krstulja M, Car A, Bonifacić D, Braut T, Kujundzić M: Nasopharyngeal angiofibroma with intracellular accumulation of SPARC - a hypothesis (SPARC in nasopharyngeal angiofibroma). Med Hypotheses; 2008;70(3):600-4
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  • [Title] Nasopharyngeal angiofibroma with intracellular accumulation of SPARC - a hypothesis (SPARC in nasopharyngeal angiofibroma).
  • Nasopharyngeal angiofibroma is a histologically benign tumor composed of stroma and vessels.
  • Some nasopharyngeal angiofibromas are resistant to surgical therapy because of extensive growth and occasionally bone destruction.
  • Because the cell of origin of nasopharyngeal angiofibroma is not recognized yet, it would be of interest to discuss molecule(s) relevant to all the cell components of the growth.
  • We propose that in nasopharyngeal angiofibroma the molecule responding to the cues mentioned above is SPARC (secreted protein acidic rich in cystein).
  • We discuss SPARC-enabling formation of molecular complexes important for the angiogenic events and present nasopharyngeal angiofibroma as a hyperplastic angiogenic machinery or a "soil" without "seed".
  • Therapeutic targeting of SPARC in nasopharyngeal angiofibroma would be targeting of a molecule at the roots of cooperation between stromatogenesis and angiogenesis, coexpressed with Ki67 in the vascular compartment.
  • Considering the intracellular accumulation of SPARC, the benefit of (anti) SPARC therapy in nasopharyngeal angiofibroma is yet to be proved.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology. Osteonectin / metabolism

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  • (PMID = 17681430.001).
  • [ISSN] 0306-9877
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Osteonectin
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49. Carrillo JF, Celis MA, Ramirez-Ortega M, Rivas B, Ochoa FJ: Osteoplastic maxillotomy for treatment of neoplasms of the nasopharynx and infratemporal fossa. Ann Otol Rhinol Laryngol; 2005 Jan;114(1 Pt 1):58-64
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  • Ten patients underwent osteoplastic maxillotomy, 3 of whom had a diagnosis of malignancy, and 7 of whom had nasopharyngeal angiofibromas (NPAs).
  • The patients who had malignancies are alive with no disease, and there was 1 recurrence among the 7 patients with NPAs.
  • [MeSH-minor] Adolescent. Adult. Aged. Angiofibroma / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Craniotomy. Esthetics. Female. Hemangiopericytoma / surgery. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Quality of Life. Treatment Outcome. Zygoma / surgery

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  • (PMID = 15697164.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. deSousa JL, Meligonis G, Malhotra R: Giant cell angiofibroma of the orbit with periosteal adherence. Clin Exp Ophthalmol; 2006 Dec;34(9):886-8
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  • [Title] Giant cell angiofibroma of the orbit with periosteal adherence.
  • We report a case of orbital giant cell angiofibroma, an unusual, recently reported benign spindle cell neoplasm.
  • Preoperative clinical assessment and radiology suggested a benign mass and early operative findings were in concordance with this.
  • The histology of giant cell angiofibroma and its principle pathological differential diagnoses is discussed.
  • As with some lymphangiomas, this is another benign orbital tumour which may present difficulties in complete surgical excision that are not anticipated based on the preoperative findings.
  • [MeSH-major] Angiofibroma / diagnosis. Giant Cell Tumors / diagnosis. Orbital Neoplasms / diagnosis. Periosteum / pathology

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  • (PMID = 17181622.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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51. Sun XF, Yan CL, Fang L, Shen FM, Liao KH: Cutaneous lesions and visceral involvement of tuberous sclerosis. Chin Med J (Engl); 2005 Feb 5;118(3):215-9
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  • BACKGROUND: Tuberous sclerosis (TS) is an autosomal dominant disorder with a significant range of clinical expressions.
  • They were followed by facial angiofibromas and Shangreen's patch in a decreasing frequency.
  • Forehead plaque, facial angiofibromas and Shagreen's patch appeared in patients at mean age of 2.6, 6.0 and 8.1 years respectively.
  • CONCLUSIONS: Cutaneous features of TS are helpful in the early diagnosis of the disease.


52. Jiang WH, Zhao SP, Xie ZH, Zhang H, Xiao JY: [Surgical approaches for different stages of nasopharyngeal angiofibromas]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2007 Jun;42(6):417-21
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  • [Title] [Surgical approaches for different stages of nasopharyngeal angiofibromas].
  • OBJECTIVE: To explore the optical surgical approaches for the resection of early and advanced stage of nasopharyngeal angiofibromas.
  • METHODS: Twenty two male patients aged 9 - 30 years (median 16 years) hospitalized in Xiangya Hospital from June 2003 to July 2006 with nasopharyngeal angiofibroma were recruited.
  • Five operative approaches were selected according classification of juvenile nasopharyngeal angiofibroma described by Fisch.
  • Six cases with stage I nasopharyngeal angiofibroma underwent endoscopic transnasal surgery.
  • CONCLUSIONS: Appropriate surgical approach should be selected according to the clinical classification and whether the tumor has extended into whole nasal cavity, lateral fossa infratemporalis, intracranial or not.
  • Such approaches might better facilitate the complete removal of nasopharyngeal angiofibromas and reduce the surgery-related injury.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 17702414.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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53. Hameed M, Clarke K, Amer HZ, Mahmet K, Aisner S: Cellular angiofibroma is genetically similar to spindle cell lipoma: a case report. Cancer Genet Cytogenet; 2007 Sep;177(2):131-4
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  • [Title] Cellular angiofibroma is genetically similar to spindle cell lipoma: a case report.
  • Cellular angiofibroma is a benign mesenchymal neoplasm of female and male genital tract composed of prominent vasculature and stromal spindle cells, often with admixture of adipose tissue.
  • Herein we describe a tumor arising in the perineal region of a 60-year-old man with morphological and immunohistochemical features of cellular angiofibroma and showing cytogenetic characteristics similar to spindle cell lipoma.
  • To our knowledge, this is the first report of cytogenetic changes in cellular angiofibroma.
  • [MeSH-major] Angiofibroma / pathology. Lipoma / pathology. Mesenchymal Stromal Cells / pathology. Nevus, Spindle Cell / pathology

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  • (PMID = 17854668.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Hunt CH, Morris JM, Lee PU, Cloft H: Progressive epistaxis in two young males: Classic presentations of juvenile nasopharyngeal angiofibroma in unusual locations. Neuroradiology; 2010 May;52(5):419-20
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  • [Title] Progressive epistaxis in two young males: Classic presentations of juvenile nasopharyngeal angiofibroma in unusual locations.
  • [MeSH-major] Angiofibroma / diagnostic imaging. Epistaxis / etiology. Nasopharyngeal Neoplasms / diagnostic imaging

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  • [Cites] Ann Surg. 1948 Mar;127(3):513-36 [17859097.001]
  • [Cites] Laryngoscope. 1992 Aug;102(8):928-33 [1323003.001]
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  • (PMID = 20127084.001).
  • [ISSN] 1432-1920
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
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55. Carrillo JF, Albores O, Ramírez-Ortega MC, Aiello-Crocifoglio V, Oñate-Ocaña LF: An audit of nasopharyngeal fibromas. Eur J Surg Oncol; 2007 Jun;33(5):655-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An audit of nasopharyngeal fibromas.
  • BACKGROUND: Nasopharyngeal angiofibroma (NA) is a vascular tumor of the nasopharynx of young males which presents rarely.
  • Our aim was to analyse outcome and prognostic factors of a case series of NA.
  • We evaluated clinical, radiological and therapeutic data for recurrence- and disease-free survival-associated prognostic factors.
  • [MeSH-major] Angiofibroma / diagnosis. Nasopharyngeal Neoplasms / diagnosis
  • [MeSH-minor] Disease-Free Survival. Follow-Up Studies. Humans. Male. Neoplasm Recurrence, Local. Prognosis. Retrospective Studies

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  • (PMID = 17329064.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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56. Duerr S, Wendler O, Aigner T, Karosi S, Schick B: Metalloproteinases in juvenile angiofibroma--a collagen rich tumor. Hum Pathol; 2008 Feb;39(2):259-68
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metalloproteinases in juvenile angiofibroma--a collagen rich tumor.
  • MMPs with gelatinase/collagenase activity have not yet been studied in juvenile angiofibroma, a unique fibrovascular tumor with prominent collagen expression.
  • Quantitative real-time polymerase chain reaction studies, Western blot analysis, immunofluorescence studies, gel zymography, and in situ zymography were used to analyze MMP-1, MMP-2, MMP-9, MMP-13, MMP-14, TIMP-1, and TIMP-2 in 9 juvenile angiofibromas and 2 inferior nasal turbinate specimens.
  • Western blot analysis detected more prominent MMP-1, MMP-2, and MMP-9 protein levels in juvenile angiofibromas compared with inferior nasal turbinates, but not MMP-13, MMP-14, TIMP-1, and TIMP-2.
  • Gel zymography indicated increased MMP-2 and MMP-9 gelatinase activity in juvenile angiofibromas compared with inferior nasal turbinates.
  • This study indicates significant expression of MMPs with gelatinase/collagenase activity in juvenile angiofibromas with evidence of a disturbed balance of MMPs to TIMPs toward enhanced MMP activity.
  • [MeSH-major] Angiofibroma / enzymology. Biomarkers, Tumor / metabolism. Collagen / metabolism. Metalloproteases / metabolism. Nose Neoplasms / enzymology

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  • (PMID = 17950779.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Tissue Inhibitor of Metalloproteinase-1; 127497-59-0 / Tissue Inhibitor of Metalloproteinase-2; 9007-34-5 / Collagen; EC 3.4.- / Metalloproteases
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57. Gupta SC, Sachin J, Savyasachi S, Ritesh J, Neha G, Singh HP: Solitary nasal schwannoma clinically presenting as an angiofibroma of the nasopharynx. Ear Nose Throat J; 2010 Jul;89(7):E28-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary nasal schwannoma clinically presenting as an angiofibroma of the nasopharynx.
  • Benign schwannomas of the nasal cavity are rare.
  • We report the case of a 17-year-old boy who presented with epistaxis associated with a unilateral nasal mass that extended into the nasopharynx.
  • In most such cases, a clinical diagnosis of angiofibroma is made.
  • [MeSH-major] Angiofibroma / diagnosis. Nasal Septum / pathology. Nasopharyngeal Neoplasms / diagnosis. Neurilemmoma / pathology. Nose Neoplasms / pathology

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  • (PMID = 20628976.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Finis D, Gümbel H: [Central retinal artery occlusion after embolization in juvenile nasopharyngeal angiofibroma]. Klin Monbl Augenheilkd; 2009 Jul;226(7):579-80
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  • [Title] [Central retinal artery occlusion after embolization in juvenile nasopharyngeal angiofibroma].
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic / adverse effects. Nasopharyngeal Neoplasms / therapy. Retinal Artery Occlusion / etiology. Retinal Artery Occlusion / surgery

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  • (PMID = 19644808.001).
  • [ISSN] 1439-3999
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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59. Romani R, Tuominen H, Hernesniemi J: Reducing intraoperative bleeding of juvenile nasopharyngeal angiofibroma. World Neurosurg; 2010 Oct-Nov;74(4-5):497-500
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reducing intraoperative bleeding of juvenile nasopharyngeal angiofibroma.
  • OBJECTIVE: To report the case of a young patient with juvenile nasopharyngeal angiofibroma (JNA) (Fisch grade IVb) operated on in a semisitting position.
  • [MeSH-major] Angiofibroma / surgery. Embolization, Therapeutic / methods. Hemorrhage / therapy. Intraoperative Complications / therapy. Nasopharyngeal Neoplasms / surgery

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21492601.001).
  • [ISSN] 1878-8769
  • [Journal-full-title] World neurosurgery
  • [ISO-abbreviation] World Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Wendler O, Schäfer R, Schick B: Mast cells and T-lymphocytes in juvenile angiofibromas. Eur Arch Otorhinolaryngol; 2007 Jul;264(7):769-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mast cells and T-lymphocytes in juvenile angiofibromas.
  • Juvenile angiofibroma (JA) is regarded as a benign fibrovascular tumour of unknown aetiology.
  • Due to its fibrovascular architecture the fibrous and vascular tumour component have been in the focus of most studies.
  • Western blot analysis supported finding of remarkable expression of the mast cell markers tryptase and chymase in JAs and indicated for both proteins similar but also different molecular weights than being observed in NM.
  • Regarding these observations JAs are certainly not only built up by vascular cells and fibrous stroma cells.
  • [MeSH-major] Angiofibroma / pathology. CD4-Positive T-Lymphocytes / pathology. CD8-Positive T-Lymphocytes / pathology. Mast Cells / pathology. Nose Neoplasms / pathology

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  • (PMID = 17310347.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.21.39 / Chymases; EC 3.4.21.59 / Tryptases
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61. Xia Y, Darling TN: Rapidly growing collagenomas in multiple endocrine neoplasia type I. J Am Acad Dermatol; 2007 May;56(5):877-80
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  • Patients with multiple endocrine neoplasia type I (MEN-I) frequently develop skin lesions including collagenomas, angiofibromas, and lipomas.
  • We report a patient with MEN-I who exhibited rapid growth of multiple collagenomas after pancreatic enucleation of a vasoactive intestinal peptide-secreting tumor (VIPoma) and excision of multiple pancreatic masses.
  • [MeSH-major] Multiple Endocrine Neoplasia Type 1 / complications. Pancreatic Neoplasms / secondary. Skin Diseases / etiology. Vipoma / surgery

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  • (PMID = 17188781.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-34-5 / Collagen
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62. Sabah M, Mohan P, Kay E: Para-testicular cellular angiofibroma: a rare tumour in a male renal transplant patient. Virchows Arch; 2006 Oct;449(4):489-92
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  • [Title] Para-testicular cellular angiofibroma: a rare tumour in a male renal transplant patient.
  • Cellular angiofibroma is a rare, benign, mesenchymal neoplasm that should be distinguished from other more aggressive mesenchymal lesions.
  • A 32-year-old male presented with a painless para-testicular mass.
  • Pathological examination showed features characteristic of cellular angiofibroma.
  • The pathogenesis of cellular angiofibroma is largely undetermined.
  • [MeSH-major] Angiofibroma / pathology. Kidney Transplantation / adverse effects. Postoperative Complications. Testicular Neoplasms / pathology

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  • (PMID = 16957933.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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63. Granata A, Basile A, Figuera M, Mignani R, Fiore CE: Spontaneous retroperitoneal hemorrhage due to massive rupture of renal angiomyolipoma treated with nephrectomy: an unusual onset of tuberous sclerosis complex. Clin Nephrol; 2009 Apr;71(4):441-4
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  • Tuberous sclerosis complex (TSC) is a genetic and systemic disorder characterized by benign hamartomatous tumors that involve multiple organ systems.
  • The classical clinical triad of TSC consists of seizure, adenoma sebaceum (facial angiofibromata) and mental retardation.
  • We describe the case of a 28 year old woman who came to the emergency department with acute postprandial abdominal pain and severe anemia due to hemorrhagic renal angiomyolipoma treated by nephrectomy in whom the following examination led to the diagnosis of TSC.


64. Kerkuta R, Kennedy CM, Benda JA, Galask RP: Vulvar cellular angiofibroma: a case report. Am J Obstet Gynecol; 2005 Nov;193(5):1750-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vulvar cellular angiofibroma: a case report.
  • Cellular angiofibroma is a benign growth initially described in 1997, with few reports to date.
  • A 31-year-old woman presented with a 3-year history of a small left labial mass, which had recently increased in size to 5 cm, and was clinically thought to be a lipoma.
  • Histologically, the mass was consistent with a cellular angiofibroma.
  • Cellular angiofibroma is a rare, benign mesenchymal lesion typically occurring on the vulva, and should be considered in the differential diagnosis of a painless, soft, vulvar mass.
  • [MeSH-major] Angiofibroma. Vulvar Neoplasms

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  • (PMID = 16260223.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / 1K23 HD045769-01
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
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65. Douglas R, Wormald PJ: Endoscopic surgery for juvenile nasopharyngeal angiofibroma: where are the limits? Curr Opin Otolaryngol Head Neck Surg; 2006 Feb;14(1):1-5
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  • [Title] Endoscopic surgery for juvenile nasopharyngeal angiofibroma: where are the limits?
  • PURPOSE OF REVIEW: This article will examine recent publications on the endoscopic management of juvenile nasopharyngeal angiofibromas.
  • RECENT FINDINGS: The use of an endoscopic approach to resect small juvenile nasopharyngeal angiofibromas is supported by excellent results from a number of operative series published in recent years.
  • Large juvenile nasopharyngeal angiofibromas continue to present a considerable surgical challenge, with most being resected by traditional open approaches.
  • However, the results achieved after the endoscopic resection of large tumours have been reported for a small number of cases.
  • This review focuses on the outcome of these cases, which would seem to compare favourably to open series, and the advances in instrumentation and techniques, that facilitate the endoscopic removal of large juvenile nasopharyngeal angiofibromas.
  • SUMMARY: Improvements in preoperative assessment and preparation, operative technique, and instrumentation potentially enable the endoscopic removal of most juvenile nasopharyngeal angiofibromas.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 16467630.001).
  • [ISSN] 1068-9508
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
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66. Zhou B, Cai T, Huang Q, Liang XH, Ni X, Wei YX, Cui SJ, Zhang L, Wang T, Liu HC, Liu M, Han DM: [Juvenile nasopharyngeal angiofibroma: endoscopic surgery and follow-up results]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Mar;45(3):180-5
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  • [Title] [Juvenile nasopharyngeal angiofibroma: endoscopic surgery and follow-up results].
  • OBJECTIVE: To present the changes of surgical approaches for the resection of juvenile nasopharyngeal angiofibromas (JNA) and the follow-up results.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 20450693.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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67. Muhammed K, Mathew J: Coexistence of two neurocutaneous syndromes: tuberous sclerosis and hypomelanosis of Ito. Indian J Dermatol Venereol Leprol; 2007 Jan-Feb;73(1):43-5
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  • He also had facial angiofibromas, ash-leaf and confetti macules and shagreen patches.
  • [MeSH-minor] Angiofibroma / complications. Brain / pathology. Child, Preschool. Epilepsy / complications. Facial Neoplasms / complications. Humans. Intellectual Disability / complications. Magnetic Resonance Imaging. Male


68. Assefa G, Alemie B: Tuberous sclerosis complex (TSC) and Klippel-Trenaunay-Weber (KTW) syndromes association of two complete phakomatoses in a single individual. Ethiop Med J; 2010 Oct;48(4):315-20
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  • Tuberous sclerosis or tuberous sclerosis complex (TSC) and Klippel-Trenaunay-Weber (KTW) syndromes are phakomatoses which are believed to be inherited separately were associated in a 21 years old female, with no family history of similar illness presented with facial rash of reddish spots or bumps, facial angiofibroma (adenoma cebaceum), which appeared on the nose and cheeks in a butterfly distribution, and sub ependymal calcific nodules on brain CT, and multiple liver, pancreas hamartomas and multiple angiomyolipomas and cysts of both kidney on ultrasound, which is consistent with a sporadic TSC, in addition, the diagnostic triad of KTW involved the left upper limb : cutaneous naevi a vascular anomaly, soft tissue and osteohypertrophy.

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  • (PMID = 21280434.001).
  • [ISSN] 0014-1755
  • [Journal-full-title] Ethiopian medical journal
  • [ISO-abbreviation] Ethiop. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ethiopia
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69. Noone P, Majid M, Vasu S: Autopsy findings in a case of tuberous sclerosis. J Forensic Leg Med; 2009 Aug;16(6):357-61
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  • Tuberous sclerosis is a neurocutaneous disorder with autosomal dominant inheritance.
  • It is characterized by the triad of seizures, mental retardation, angiofibromas of the face though the triad is not always complete.
  • He also had cortical thickening of bones, cortical tubers of brain, polycystic kidney disease.
  • [MeSH-minor] Adult. Angiofibroma / pathology. Asphyxia / pathology. Facial Neoplasms / pathology. Forensic Pathology. Humans. Lipomatosis / pathology. Male. Neck Injuries / pathology. Polycystic Kidney Diseases / pathology. Suicide

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  • (PMID = 19573851.001).
  • [ISSN] 1878-7487
  • [Journal-full-title] Journal of forensic and legal medicine
  • [ISO-abbreviation] J Forensic Leg Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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70. Medeiros F, Erickson-Johnson MR, Keeney GL, Clayton AC, Nascimento AG, Wang X, Oliveira AM: Frequency and characterization of HMGA2 and HMGA1 rearrangements in mesenchymal tumors of the lower genital tract. Genes Chromosomes Cancer; 2007 Nov;46(11):981-90
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  • We evaluated 90 cases of mesenchymal tumors of the lower genital tract that comprised 42 AAMs, 18 AMFs, 6 cellular angiofibromas, 5 fibroepithelial stromal polyps, 15 genital leiomyomas, 3 superficial angiomyxomas, and 1 spindle cell lipoma.

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  • [Copyright] Copyright (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17654722.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Complementary; 0 / HMGA Proteins
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71. Lin Y, Qiu JH, Qiao L, He LS, Zha DJ: Le Fort I osteotomy for extensive juvenile nasopharyngeal angiofibroma: a retrospective study. Adv Ther; 2008 Oct;25(10):1057-64
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  • [Title] Le Fort I osteotomy for extensive juvenile nasopharyngeal angiofibroma: a retrospective study.
  • INTRODUCTION: Juvenile nasopharyngeal angiofibroma (JNA) is a rare, nonencapsulated, benign neoplasm typically diagnosed in adolescent boys.
  • All the angiofibromas had extended into the pterygomaxillary space and infratemporal fossa.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Osteotomy, Le Fort / methods

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  • (PMID = 18836867.001).
  • [ISSN] 0741-238X
  • [Journal-full-title] Advances in therapy
  • [ISO-abbreviation] Adv Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Tsai CJ, Wang HM, Lu IC, Tai CF, Wang LF, Soo LY, Lu DV: Seizure after local anesthesia for nasopharyngeal angiofibroma. Kaohsiung J Med Sci; 2007 Feb;23(2):97-100
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  • [Title] Seizure after local anesthesia for nasopharyngeal angiofibroma.
  • We report a young male patient who experienced seizure after local injection of 3 mL 2% lidocaine with epinephrine 1:200,000 around a recurrent nasal angiofibroma.
  • [MeSH-major] Anesthesia, Local / adverse effects. Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Seizures / etiology

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  • (PMID = 17339174.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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73. Dere H, Ozcan KM, Ergul G, Bahar S, Ozcan I, Kulacoglu S: Extranasopharyngeal angiofibroma of the cheek. J Laryngol Otol; 2006 Feb;120(2):141-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extranasopharyngeal angiofibroma of the cheek.
  • Angiofibromas rarely localize in extranasopharyngeal sites.
  • The most common site for extranasopharyngeal angiofibromas is the maxillary sinus.
  • The ethmoid and sphenoid sinuses, nasal septum, middle and inferior turbinates, conjunctiva, molar and retromolar region, and larynx are other sites where extranasopharyngeal angiofibromas have been reported.
  • Only one case of buccal extranasopharyngeal angiofibroma has been reported to date.
  • We present a case of buccal extranasopharyngeal angiofibroma that was excised completely following embolization and we also review the literature.
  • [MeSH-major] Angiofibroma / pathology. Mouth Neoplasms / pathology. Vascular Neoplasms / pathology

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  • (PMID = 16359575.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 13
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74. Zhang QX, Ye J, Zhang SM, Li M: [Endoscopic nasal surgery in the treatment of nasopharyngeal angiofibroma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2005 Mar;40(3):222-3
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  • [Title] [Endoscopic nasal surgery in the treatment of nasopharyngeal angiofibroma].
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 15952579.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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75. Sciarretta V, Pasquini E, Farneti G, Frank G, Mazzatenta D, Calbucci F: Endoscopic sinus surgery for the treatment of vascular tumors. Am J Rhinol; 2006 Jul-Aug;20(4):426-31
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  • BACKGROUND: This study points out the effectiveness of the endoscopic approach for the treatment of vascular lesions such as angiofibroma, hemangioma, and hemangiopericytoma involving the nose and paranasal sinuses.
  • RESULTS: The follow-up of this series varied from 6 to 75 months (mean, 23 months); only one recurrence (8%) was observed in the juvenile angiofibroma group encountered 20 months postoperatively.
  • The average intraoperative blood loss for the removal of the juvenile angiofibroma group was 300 mL and it was 100 mL for the other vascular tumors.
  • Even in the presence of a lesion with limited intracranial extension, the tumor still may be amenable to an endoscopic approach alone.

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  • (PMID = 16955773.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Laurent A, Wassef M, Chapot R, Wang Y, Houdart E, Feng L, Tran Ba Huy P, Merland JJ: Partition of calibrated tris-acryl gelatin microspheres in the arterial vasculature of embolized nasopharyngeal angiofibromas and paragangliomas. J Vasc Interv Radiol; 2005 Apr;16(4):507-13
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  • [Title] Partition of calibrated tris-acryl gelatin microspheres in the arterial vasculature of embolized nasopharyngeal angiofibromas and paragangliomas.
  • PURPOSE: To determine the location of calibrated tris-acryl gelatin microspheres (TGMs) in the arterial vasculature of nasopharyngeal angiofibromas (NAFs) and paragangliomas (PGs).
  • [MeSH-major] Acrylic Resins / therapeutic use. Angiofibroma / blood supply. Embolization, Therapeutic / methods. Gelatin / therapeutic use. Nasopharyngeal Neoplasms / blood supply. Paraganglioma / blood supply

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  • (PMID = 15802450.001).
  • [ISSN] 1051-0443
  • [Journal-full-title] Journal of vascular and interventional radiology : JVIR
  • [ISO-abbreviation] J Vasc Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acrylic Resins; 0 / Coloring Agents; 0 / Fluorescent Dyes; 0 / trisacryl gelatin microspheres; 9000-70-8 / Gelatin
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77. Shunyu NB, Thakar A, Gupta V: Complete resolution of stage IIIB juvenile nasopharyngeal angiofibroma with radiation therapy. Indian J Otolaryngol Head Neck Surg; 2008 Sep;60(3):238-41
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  • [Title] Complete resolution of stage IIIB juvenile nasopharyngeal angiofibroma with radiation therapy.
  • Juvenile nasopharyngeal angiofibroma is a benign, locally aggressive, vascular tumour of adolescent males.
  • Hence we are re-affirming the earlier studies than angiofibroma mass regresses gradually after completion of radiotherapy.
  • Radiotherapy is a useful way of treating angiofibroma with significant intracranial extension.

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  • (PMID = 23120551.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450647
  • [Keywords] NOTNLM ; Angiofibroma / Intracranial extension / Radiotherapy
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78. Schick B: [Specific aspects of juvenile angiofibromas]. HNO; 2007 Jan;55(1):17-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Specific aspects of juvenile angiofibromas].
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / diagnosis. Nasopharyngeal Neoplasms / therapy. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / prevention & control

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  • (PMID = 17160660.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 20
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79. Wee SA, Fangman B: Tuberous sclerosis. Dermatol Online J; 2007;13(1):22
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  • Histopathologic examination was consistent with angiofibromas.
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Female. Frontal Bone / radiography. Genetic Predisposition to Disease. Humans. Lacrimal Apparatus / pathology. Middle Aged. Skin / pathology. Tomography, X-Ray Computed

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  • (PMID = 17511955.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Fernandez-Flores A: Solitary oral fibromas of the tongue show similar morphologic features to fibrous papule of the face: a study of 31 cases. Am J Dermatopathol; 2010 Jul;32(5):442-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary oral fibromas of the tongue show similar morphologic features to fibrous papule of the face: a study of 31 cases.
  • The morphologic similarities between fibrous papules of the face and multiple oral fibromas were mentioned long ago, mainly in the context of phakomatoses.
  • Both lesions have been considered to be different types of angiofibromas.
  • We tried to investigate if solitary oral fibromas also share morphologic features with fibrous papules of the face.
  • For this purpose, we designed a retrospective study retrieving 31 fibromas of the tongue from 30 different patients and studied a control group of 20 fibrous papules of the face from 20 different patients.
  • From the oral fibromas, 15 lesions presented as dome shape, whereas 16 lesions presented as polypoid.
  • In all the lesions, we found a common pattern: a fibrous and collagenized stroma, with prominent vessels.
  • Also, we specifically searched for 4 morphologic features: dilated blood vessels, concentric perivascular fibrosis, multinucleated cells, and mast cells.
  • These findings were similar to the ones described in fibrous papules of the face, which were also present in our control group of 20 fibrous papules.
  • Therefore, we conclude that the sporadic type of fibroma shares many morphologic features with the fibrous papules of the face.
  • This would be similar to the morphologic relation, already described, between fibrous papules of the face and oral fibromas of phakomatoses.
  • [MeSH-major] Angiofibroma / pathology. Neurocutaneous Syndromes / pathology. Skin Neoplasms / pathology. Tongue Neoplasms / pathology

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  • (PMID = 20421776.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lymphokines; 0 / fibrosin
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81. Bleier BS, Kennedy DW, Palmer JN, Chiu AG, Bloom JD, O'Malley BW Jr: Current management of juvenile nasopharyngeal angiofibroma: a tertiary center experience 1999-2007. Am J Rhinol Allergy; 2009 May-Jun;23(3):328-30
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  • [Title] Current management of juvenile nasopharyngeal angiofibroma: a tertiary center experience 1999-2007.
  • BACKGROUND: Over the past 10 years, the management of juvenile nasopharyngeal angiofibroma (JNA) has been redefined because of the improvement of transnasal skull base techniques.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 19490810.001).
  • [ISSN] 1945-8924
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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82. Prabhu S, Mahesh KP: Tuberous sclerosis with oral angiofibroma: case report. Br J Oral Maxillofac Surg; 2010 Apr;48(3):205-7
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  • [Title] Tuberous sclerosis with oral angiofibroma: case report.
  • Tuberous sclerosis is a multisystem disorder characterised by the formation of hamartomas in various parts of the body.
  • We present a patient who presented with facial angiofibromas (adenoma sebaceum), shagreen patches, and epileptic seizures.
  • Oral papules showed histological features of angiofibroma, which was peculiar to this case.
  • [MeSH-major] Angiofibroma / pathology. Facial Neoplasms / pathology. Mouth Neoplasms / pathology. Tuberous Sclerosis / pathology

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  • [Copyright] 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 19640621.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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83. Falkner JA, Falkner JW, Andrews PC: ProteomeCommons.org JAF: reference information and tools for proteomics. Bioinformatics; 2006 Mar 1;22(5):632-3
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  • [Title] ProteomeCommons.org JAF: reference information and tools for proteomics.
  • The Java Analysis Framework (JAF) for proteomics provides a freely usable, open-source library of Java code that abstracts all of the aforementioned data, enabling more rapid development of proteomics tools.
  • The JAF also includes several user tools that can be run directly from a web browser.

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  • (PMID = 16434446.001).
  • [ISSN] 1367-4803
  • [Journal-full-title] Bioinformatics (Oxford, England)
  • [ISO-abbreviation] Bioinformatics
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / P41-RR018627
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Proteins
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84. Gaillard AL, Anastácio VM, Piatto VB, Maniglia JV, Molina FD: A seven-year experience with patients with juvenile nasopharyngeal angiofibroma. Braz J Otorhinolaryngol; 2010 Mar-Apr;76(2):245-50
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  • [Title] A seven-year experience with patients with juvenile nasopharyngeal angiofibroma.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor in adolescent males.
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic. Nasopharyngeal Neoplasms / therapy

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  • (PMID = 20549087.001).
  • [ISSN] 1808-8686
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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85. Hajosch R, Suckfuell M, Oesser S, Ahlers M, Flechsenhar K, Schlosshauer B: A novel gelatin sponge for accelerated hemostasis. J Biomed Mater Res B Appl Biomater; 2010 Aug;94(2):372-9
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  • The sponge was shown to bring about rapid hemostasis when it was administered in a young patient suffering from acute bleeding of a pharyngeal angiofibroma, even though the patient had been treated with an anticoagulant because of a transient ischemic attack.
  • [MeSH-minor] Absorption. Angiofibroma / blood supply. Angiofibroma / pathology. Blood. Blood Loss, Surgical / prevention & control. Child. Hemorrhage / prevention & control. Hemostasis, Surgical / methods. Humans. Male. Veins

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  • (PMID = 20578223.001).
  • [ISSN] 1552-4981
  • [Journal-full-title] Journal of biomedical materials research. Part B, Applied biomaterials
  • [ISO-abbreviation] J. Biomed. Mater. Res. Part B Appl. Biomater.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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86. Córdoba López A, Cerezo Arias Mde L, Pérez Frutos MD, Granado Martínez D, Jimeno Torres B: [Rhabdomyolysis following lengthy surgery on a nasopharyngeal angiofibroma]. Cir Esp; 2010 Sep;88(3):193-5
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  • [Title] [Rhabdomyolysis following lengthy surgery on a nasopharyngeal angiofibroma].
  • [Transliterated title] Rabdomiolisis tras intervención de angiofibroma de cavum de larga duración.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Postoperative Complications / etiology. Rhabdomyolysis / etiology

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  • (PMID = 20074715.001).
  • [ISSN] 1578-147X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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87. Drut R: Polypoid dermal dendrocytic hamartoma in a giant congenital melanocytic nevus. Int J Surg Pathol; 2007 Jan;15(1):73-6
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  • The differential diagnosis included dermatofibrosarcoma protuberans, giant-cell fibroblastoma, angiofibroma, Bednar tumor, other types of dermal dendrocytic hamartoma, and neurocristic cutaneous hamartoma.
  • [MeSH-minor] Antigens, CD34. Humans. Immunohistochemistry. Infant. Male. Skin Diseases / complications. Skin Diseases / pathology. Skin Neoplasms / complications. Skin Neoplasms / pathology

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  • (PMID = 17172504.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34
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88. Rzaev RM: [The role of angiography in diagnosis and surgical treatment of patients with juvenile angiofibroma of the nasopharynx]. Vestn Otorinolaringol; 2007;(4):18-22
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  • [Title] [The role of angiography in diagnosis and surgical treatment of patients with juvenile angiofibroma of the nasopharynx].
  • 22 of them had juvenile nasopharyngeal angiofibroma (JNA), 8 patients had early cancer.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Angiography / methods. Carotid Arteries / radiography. Nasopharyngeal Neoplasms / diagnosis. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 17828107.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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89. Tardío JC: Leiomyomatous nodules in a cellular angiofibroma: a hitherto unreported finding. Virchows Arch; 2009 May;454(5):595-8
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  • [Title] Leiomyomatous nodules in a cellular angiofibroma: a hitherto unreported finding.
  • Cellular angiofibroma is a benign tumor of the superficial soft tissues of the vulvovaginal and inguinoscrotal regions of adult patients.
  • The case of a 44-year-old female with a perineal cellular angiofibroma containing small leiomyomatous nodules is described in this case report.
  • These nodules could probably be originated from smooth muscle differentiation of the spindle cell component of an otherwise conventional cellular angiofibroma.
  • To our knowledge, the finding of distinct leiomyomatous nodules within a cellular angiofibroma has not been previously reported.
  • [MeSH-major] Angiofibroma / pathology. Leiomyoma / pathology. Neoplasms, Multiple Primary / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19301032.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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90. Durko M, Murlewska A, Gryczyński M, Ratyńska M, Pietruszewska W: [Angiofibroma of the nasal cavity and anterior ethmoid cells--problems in differential diagnosis]. Otolaryngol Pol; 2007;61(5):736-9
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  • [Title] [Angiofibroma of the nasal cavity and anterior ethmoid cells--problems in differential diagnosis].
  • [Transliterated title] Angiofibroma jamy nosa i komórek sitowych przednich u kobiety--problemy diagnostyki róznicowej.
  • BACKGROUND: Nasal angiofibromas are commonly called juvenile nasal angiofibromas (JNA) because of the almost exclusive occurrence in adolescent males.
  • It is a relatively rare benign fibrovascular tumor originating in the posterior lateral wall of the nasopharynx with only a very few cases diagnosed in females.
  • CASE REPORT: Authors present a case of a 26 y.o. woman with JNA in left nasal cavity with extension to the anterior left ethmoid cells diagnosed and surgically treated at the ENT Department, Medical University of Lodz.
  • CONCLUSION: Although angiofibroma in females is an extremely rare tumor of a sinonasal tract it should be taken into consideration in the differential diagnosis of all nasal cavity tumors (especially solitary fibrous tumor).
  • [MeSH-major] Angiofibroma / pathology. Ethmoid Sinus / pathology. Nose Neoplasms / pathology

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  • (PMID = 18552009.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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91. McQueeney RJ, Ma J, Chang S, Yan JQ, Hehlen M, Trouw F: Stabilization of charge ordering in La1/3Sr2/3FeO3-delta by magnetic exchange. Phys Rev Lett; 2007 Mar 23;98(12):126402
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  • In LSFO, the measured ratio of ferromagnetic exchange between Fe3+-Fe5+ pairs (JF) and antiferromagnetic exchange between Fe3+-Fe3+ pairs (JAF) fulfills the criterion for charge ordering driven by magnetic interactions (|JF/JAF|>1).
  • The 30% reduction of JAF as compared to LFO indicates that doped holes are delocalized, and charge ordering occurs without a dominant influence from Coulomb interactions.

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  • (PMID = 17501139.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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92. Kato H, Kanematsu M, Sato E, Ito N, Furui T, Hirose Y: Magnetic resonance imaging findings of fibroepithelial polyp of the vulva: radiological-pathological correlation. Jpn J Radiol; 2010 Oct;28(8):609-12
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  • Within the lesion, abundant fibrous tissue was visualized as stratiform hypointense areas on T2-weighted magnetic resonance imaging (MRI) scans.
  • Although the MRI findings of fibroepithelial polyps of the vulva are often similar to those of aggressive angiomyxoma, angiomyofibroblastoma, and cellular angiofibroma, a fibroepithelial polyp should be considered when radiological images demonstrate the following features: stratiform hypointense areas surrounded by patchy hyperintense areas on T2-weighted MRI and hyperintense areas on T1-weighted MRI.

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  • (PMID = 20972861.001).
  • [ISSN] 1867-108X
  • [Journal-full-title] Japanese journal of radiology
  • [ISO-abbreviation] Jpn J Radiol
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93. Eloy P, Watelet JB, Hatert AS, de Wispelaere J, Bertrand B: Endonasal endoscopic resection of juvenile nasopharyngeal angiofibroma. Rhinology; 2007 Mar;45(1):24-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endonasal endoscopic resection of juvenile nasopharyngeal angiofibroma.
  • Juvenile angiofibroma (JNA) is a rare benign but locally aggressive tumour of the nasopharynx that primarily occurs in adolescent males.
  • According to Radkowski's classification (Table 1), one patient was stage Ia, one was stage Ib and four patients were stage IIb.
  • All patients but one were free of disease.
  • Based upon the recent international literature, endonasal surgery combined with a preoperative embolization of the arterial supply is indicated for small and middle size JNAs but also for large tumours extended to the pterygopalatine fossa and medial aspect of the infratemporal fossa.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 17432065.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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94. Momeni AJ, Roberts CC, Chew FS: Imaging of chronic and exotic sinonasal disease: self-assessment module. AJR Am J Roentgenol; 2007 Dec;189(6 Suppl):S46-8
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  • [Title] Imaging of chronic and exotic sinonasal disease: self-assessment module.
  • This article focuses on the anatomy, pathophysiology, microbiology, and diagnosis of sinonasal disease, including chronic and fungal sinusitis, juvenile nasopharyngeal angiofibroma, inverted papilloma, and chondrosarcoma.
  • [MeSH-minor] Angiofibroma / pathology. Angiofibroma / radiography. Chondrosarcoma / pathology. Chondrosarcoma / radiography. Chronic Disease. Humans. Mycoses. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / radiography. Papilloma, Inverted / pathology. Papilloma, Inverted / radiography

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  • (PMID = 19642260.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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95. Ashraf M, Kumar P, Reza MA, Ragesh KP: Neoplastic diseases of the head & neck in children. Indian J Otolaryngol Head Neck Surg; 2006 Oct;58(4):343-6
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  • [Title] Neoplastic diseases of the head & neck in children.
  • The cervicofacial malignancies presents a unique challenge owing to potential adverse effects of both the disease process and the treatment employed on critical developing head and neck structures.This study comprised of 106 children below 12 years age group conducted during 1999-2003 at JNMC, Aligarh.
  • Of 106 cases 70 were benign neoplasms and 36 malignant neoplasms.
  • Nasopharyngeal angiofibroma was the commonest benign tumour and lymphoma was the commonest malignant neoplasm.
  • Team approach is required for mitigation of the disease process.

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  • (PMID = 23120341.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450388
  • [Keywords] NOTNLM ; Lymphoma / Nasopharyngeal angiofibroma / Neoplasm / Rhabdomyosarcoma
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96. Rauktys A, Lee N, Lee L, Dabora SL: Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model. BMC Dermatol; 2008;8:1
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  • These findings could lead to a novel treatment approach for facial angiofibromas and other TSC skin lesions.
  • [MeSH-minor] Administration, Cutaneous. Animals. Cell Line, Tumor. Disease Models, Animal. Mice. Mice, Nude. Neoplasm Transplantation. Skin Absorption. Survival Analysis. TOR Serine-Threonine Kinases

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  • (PMID = 18226258.001).
  • [ISSN] 1471-5945
  • [Journal-full-title] BMC dermatology
  • [ISO-abbreviation] BMC Dermatol.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK066366
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Enzyme Inhibitors; EC 2.7.- / Protein Kinases; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.1.1 / mTOR protein, mouse; W36ZG6FT64 / Sirolimus
  • [Other-IDs] NLM/ PMC2266897
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97. Sinha R, Das S, Ray S, Banerjee P, Sadhu P: Nasopharyngeal angiofibroma: rare presentations. Ear Nose Throat J; 2008 Dec;87(12):E26
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  • [Title] Nasopharyngeal angiofibroma: rare presentations.
  • Nasopharyngeal angiofibromas are benign tumors of the nasopharynx that occur in adolescent boys.
  • Two interesting cases of angiofibroma with atypical presentations, showing extensive spread in multiple directions, are reported here.
  • In one case, the angiofibroma exited the right nostril as a large polypoidal mass and also presented as an intraoral tumor in the right upper gingivo-alveolar region.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 19105131.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Farmer JP, Lamba M, McDonald H, Commons AS: Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis. Can J Ophthalmol; 2006 Apr;41(2):216-20
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  • [Title] Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis.
  • CASE REPORT: A 57-year-old woman presented with a 16-month history of a slowly growing mass in the medial aspect of her right lower eyelid.
  • Histopathologic examination revealed a giant cell angiofibroma, which was subsequently excised.
  • COMMENTS: Giant cell angiofibroma is a benign spindle cell neoplasm characterized by multinucleated giant cells and pseudovascular spaces with a propensity to occur in the anterior soft tissues of the orbit of middle-aged adults.
  • It is part of a wide differential diagnosis of tumours that can be separated by various histologic and immunohistochemical features, which are discussed in the report.

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  • (PMID = 16767212.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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99. Starlinger V, Wendler O, Gramann M, Schick B: Laminin expression in juvenile angiofibroma indicates vessel's early developmental stage. Acta Otolaryngol; 2007 Dec;127(12):1310-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laminin expression in juvenile angiofibroma indicates vessel's early developmental stage.
  • CONCLUSION: This study confirms the wide range of vascular architecture in juvenile angiofibromas.
  • Proof of laminin alpha2 expression in tumour vessels is suggested to indicate presence of vessels of early developmental stage in juvenile angiofibromas, supporting the concept that plexus remnants of the first branchial arch artery contribute to the vascular tumour component.
  • The goal of this study was to analyse the expression of laminins in juvenile angiofibromas.
  • MATERIALS AND METHODS: A detailed analysis of the laminin isoform expression was performed by immunofluorescence staining for laminin chains alpha1, alpha2, alpha3, alpha4, alpha5, beta1, beta2, beta3, gamma1, gamma2, and gamma3 on cryosections of 10 juvenile angiofibromas and inferior nasal turbinate tissue for control.
  • RESULTS: Vascular staining of the different laminin chains revealed areas of differential vessel density in juvenile angiofibromas and irregularities in vessel size, configuration and architecture.
  • Similar to vessels in nasal turbinates, laminins alpha4, alpha5, beta1, beta2 and gamma1 were found to be expressed in juvenile angiofibroma vessels.
  • In contrast to vessels of nasal turbinates, staining for alpha2 and alpha3 chains was only detected in vessels of juvenile angiofibromas.
  • [MeSH-major] Angiofibroma / pathology. Basement Membrane / metabolism. Laminin / metabolism. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 17851944.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Laminin
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100. Thuesen AD, Jakobsen J, Nepper-Rasmussen J: [Treatment of juvenile angiofibroma with particle embolization and endoscopic surgery]. Ugeskr Laeger; 2005 Aug 22;167(34):3167-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment of juvenile angiofibroma with particle embolization and endoscopic surgery].
  • [Transliterated title] Behandling af juvenile angiofibromer med partikelembolisering og endoskopisk kirurgi.
  • INTRODUCTION: Juvenile angiofibroma is a benign, rich vascular nasal tumor, and the biggest complication in surgery is the great loss of blood.
  • DISCUSSION: Endovascular embolization of juvenile angiofibromas followed by endoscopic surgery is considered to be the preferred treatment method today.
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / therapy

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  • [CommentIn] Ugeskr Laeger. 2005 Nov 21;167(47):4482 [16305784.001]
  • (PMID = 16117915.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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