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6. Łukomski M, Danilewicz M, Pajor A: [Juvenile angiofibroma in adults]. Otolaryngol Pol; 2008;62(1):20-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile angiofibroma in adults].
  • INTRODUCTION: Juvenile nasopharyngeal angiofibroma is a benign lesion which is characterized by three distinctive features: it occurs only in one sex, one period of age and in one location in the organism.
  • MATERIAL AND METHOD: Basing on literature and our series concerning 36 patients treated during 50 years, we present atypical cases of angiofibroma.
  • Our study reports three cases of angiofibroma, two of them concerning males aged 34 and 49 years and one case - female aged 68 years.
  • Results of histological examination of our atypical cases were similar as in angiofibromas observed in adolescents.
  • CONCLUSION: Our study concerning the occurrence of juvenile angiofibroma in adults, also in female, as the other observations from literature may constitute some remarks in discussion about the pathogenesis and clinics of this tumor.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 18637416.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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7. de Brito Macedo Ferreira LM, Gomes EF, Azevedo JF, Souza JR, de Paula Araújo R, do Nascimento Rios AS: Endoscopic surgery of nasopharyngeal angiofibroma. Braz J Otorhinolaryngol; 2006 Jul-Aug;72(4):475-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic surgery of nasopharyngeal angiofibroma.
  • Nasopharyngeal angiofibroma is a vascular benign tumor that affects young men, and surgery is the treatment of choice.
  • Endoscopic surgery has been used to excise tumors in their initial stages, when there is no evidence of residual or recurrent disease.
  • AIM: The aim of this study is to evaluate the endoscopic approach preceded by tumor embolization as treatment option for stages II to III angiofibroma.
  • CONCLUSION: Based on the results, we may conclude that the endoscopic approach, when preceded by embolization, is effective to treat angiofibromas in their initial stages, with reduced postoperative morbidity.
  • [MeSH-major] Angiofibroma / therapy. Nasopharyngeal Neoplasms / therapy

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  • (PMID = 17143426.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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8. Schick B, Wemmert S, Jung V, Steudel WI, Montenarh M, Urbschat S: Genetic heterogeneity of the MYC oncogene in advanced juvenile angiofibromas. Cancer Genet Cytogenet; 2006 Jan 1;164(1):25-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic heterogeneity of the MYC oncogene in advanced juvenile angiofibromas.
  • Despite their benign histological appearance, juvenile angiofibromas sometimes exhibit an aggressive growth behavior.
  • Because intensive cross-talk among beta-catenin, androgen receptor, and C-MYC has been detected recently, we analyzed expression of the C-MYC protooncogene (MYC) on the genetic, transcriptional and translational level in seven sporadic juvenile angiofibromas.
  • Two-color in situ hybridization analyses for chromosome 8 and MYC found in all seven juvenile angiofibromas significant MYC losses.
  • In the three advanced juvenile angiofibromas of this series (Fisch stages III and IV) additional significant MYC gains were observed demonstrating a genetic heterogeneity for the MYC protooncogene.
  • Semiquantitative RT-PCR analyses from laser microdissected endothelial cells and fibroblasts found no differences of C-MYC mRNA levels, leaving open the question of the neoplastic cell in juvenile angiofibromas.
  • The finding of genetic MYC heterogeneity associated with C-MYC overexpression on the mRNA and protein level in advanced juvenile angiofibromas indicates involvement of the MYC oncogene in aggressive growth behavior.
  • [MeSH-major] Angiofibroma / genetics. Genes, myc. Genetic Heterogeneity

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  • (PMID = 16364759.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins c-myc; 0 / RNA, Messenger; 0 / Receptors, Androgen; 0 / Transforming Growth Factor beta; 0 / beta Catenin
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9. Szymańska A, Gołabek W, Siwiec H, Pietura R, Szczerbo-Trojanowska M: [Juvenile angiofibroma: the value of CT and MRI for treatment planning and follow-up]. Otolaryngol Pol; 2005;59(1):85-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile angiofibroma: the value of CT and MRI for treatment planning and follow-up].
  • Juvenile angiofibroma is a rare, benign, hypervascular, nasopharyngeal tumour.
  • There were 40 patients with juvenile angiofibroma.
  • [MeSH-major] Angiofibroma / diagnosis. Magnetic Resonance Angiography. Nasopharyngeal Neoplasms / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 15915924.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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10. Starlinger V, Wendler O, Gramann M, Schick B: Laminin expression in juvenile angiofibroma indicates vessel's early developmental stage. Acta Otolaryngol; 2007 Dec;127(12):1310-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laminin expression in juvenile angiofibroma indicates vessel's early developmental stage.
  • CONCLUSION: This study confirms the wide range of vascular architecture in juvenile angiofibromas.
  • Proof of laminin alpha2 expression in tumour vessels is suggested to indicate presence of vessels of early developmental stage in juvenile angiofibromas, supporting the concept that plexus remnants of the first branchial arch artery contribute to the vascular tumour component.
  • The goal of this study was to analyse the expression of laminins in juvenile angiofibromas.
  • MATERIALS AND METHODS: A detailed analysis of the laminin isoform expression was performed by immunofluorescence staining for laminin chains alpha1, alpha2, alpha3, alpha4, alpha5, beta1, beta2, beta3, gamma1, gamma2, and gamma3 on cryosections of 10 juvenile angiofibromas and inferior nasal turbinate tissue for control.
  • RESULTS: Vascular staining of the different laminin chains revealed areas of differential vessel density in juvenile angiofibromas and irregularities in vessel size, configuration and architecture.
  • Similar to vessels in nasal turbinates, laminins alpha4, alpha5, beta1, beta2 and gamma1 were found to be expressed in juvenile angiofibroma vessels.
  • In contrast to vessels of nasal turbinates, staining for alpha2 and alpha3 chains was only detected in vessels of juvenile angiofibromas.
  • [MeSH-major] Angiofibroma / pathology. Basement Membrane / metabolism. Laminin / metabolism. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 17851944.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Laminin
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11. Thornton M, Mahesh BN, Lang J: Endoscopic resection of a juvenile angiofibroma: the role of the XPS microdebrider. J Laparoendosc Adv Surg Tech A; 2005 Apr;15(2):194-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic resection of a juvenile angiofibroma: the role of the XPS microdebrider.
  • Juvenile angiofibromas are vascular tumors found almost exclusively in the adolescent male.
  • Although benign, their clinical course can be aggressive and can result in major morbidity and mortality.
  • Endoscopic transnasal resection of juvenile angiofibromas, confined to the nose, paranasal sinuses, pterygopalatine fossa, and medial infratemporal fossa, has been a significant advance in their management, eliminating or reducing the need for extensive soft tissue and bony dissection of traditional surgical approaches.
  • We discuss a case of a juvenile angiofibroma resected transnasally using the XPS microdebrider (Medtonic Xomed, Jacksonville, Florida) and outline the role of this instrument in this surgery.
  • [MeSH-major] Angiofibroma / surgery. Debridement / instrumentation. Endoscopy / methods. Head and Neck Neoplasms / surgery

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  • (PMID = 15898917.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. El-Banhawy OA, Ragab A, El-Sharnoby MM: Surgical resection of type III juvenile angiofibroma without preoperative embolization. Int J Pediatr Otorhinolaryngol; 2006 Oct;70(10):1715-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical resection of type III juvenile angiofibroma without preoperative embolization.
  • OBJECTIVES/HYPOTHESIS: To evaluate the outcome of surgical resection of type III juvenile angiofibroma without preoperative embolizationo in 20 young male patients.
  • PATIENTS AND METHODS: Twenty young male patients with type III JAF (based on Fisch classification by CT/MRI or both), were operated on by endoscopic-assisted midfacial degloving approach without preoperative embolization.
  • Endoscopic transnasal removal of the recurrent JAF was done successfully under local anesthesia in the first patient and under general anesthesia in the second with no recurrence during the follow up period.
  • CONCLUSIONS: Surgical resection of stage III JAF without embolization through endoscopic assisted midfacial degloving approach can be used as an adequate surgical technique with acceptable intraoperative blood loss and low rate of recurrence.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 16904759.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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13. Schick B, Wemmert S, Bechtel U, Nicolai P, Hofmann T, Golabek W, Urbschat S: Comprehensive genomic analysis identifies MDM2 and AURKA as novel amplified genes in juvenile angiofibromas. Head Neck; 2007 May;29(5):479-87
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comprehensive genomic analysis identifies MDM2 and AURKA as novel amplified genes in juvenile angiofibromas.
  • BACKGROUND: Frequent beta-catenin mutations have been detected in juvenile angiofibromas, but the tumor pathogenesis remains unknown.
  • CONCLUSION: Metaphase-CGH results confirmed numerous chromosomal aberrations in juvenile angiofibromas.
  • AURKA and MDM2 were identified as interesting novel amplified genes in juvenile angiofibromas.
  • [MeSH-major] Angiofibroma / genetics. Chromosome Aberrations. Head and Neck Neoplasms / genetics. Protein-Serine-Threonine Kinases / genetics. Proto-Oncogene Proteins c-mdm2 / genetics

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  • [Copyright] (c) 2006 Wiley Periodicals, Inc.
  • (PMID = 17120309.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.11.1 / AURKA protein, human; EC 2.7.11.1 / Aurora Kinase A; EC 2.7.11.1 / Aurora Kinases; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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4. Gramann M, Wendler O, Haeberle L, Schick B: Prominent collagen type VI expression in juvenile angiofibromas. Histochem Cell Biol; 2009 Jan;131(1):155-64

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prominent collagen type VI expression in juvenile angiofibromas.
  • Although, juvenile angiofibromas (JAs) often exhibit an aggressive growth pattern, the collagen type VI expression of this fibrovascular tumour has not been addressed so far.
  • [MeSH-major] Angiofibroma / metabolism. Collagen Type VI / metabolism

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  • (PMID = 18797915.001).
  • [ISSN] 1432-119X
  • [Journal-full-title] Histochemistry and cell biology
  • [ISO-abbreviation] Histochem. Cell Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Collagen Type VI
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15. Thuesen AD, Jakobsen J, Nepper-Rasmussen J: [Treatment of juvenile angiofibroma with particle embolization and endoscopic surgery]. Ugeskr Laeger; 2005 Aug 22;167(34):3167-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment of juvenile angiofibroma with particle embolization and endoscopic surgery].
  • [Transliterated title] Behandling af juvenile angiofibromer med partikelembolisering og endoskopisk kirurgi.
  • INTRODUCTION: Juvenile angiofibroma is a benign, rich vascular nasal tumor, and the biggest complication in surgery is the great loss of blood.
  • DISCUSSION: Endovascular embolization of juvenile angiofibromas followed by endoscopic surgery is considered to be the preferred treatment method today.
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / therapy

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  • [CommentIn] Ugeskr Laeger. 2005 Nov 21;167(47):4482 [16305784.001]
  • (PMID = 16117915.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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16. Padilla Parrado M, Díaz Sastre MA, Jiménez Antolín JA, Caro García MA: [Juvenile nasopharyngeal angiofibroma]. An Otorrinolaringol Ibero Am; 2005;32(4):361-71

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Angiofibroma nasofaringeo juvenil. Situación actual.
  • Juvenile Juvenile nasopharyngeal angiofibroma (JNA) is a benign and highly vascular tumor.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 16156366.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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17. Tyagi I, Syal R, Goyal A: Recurrent and residual juvenile angiofibromas. J Laryngol Otol; 2007 May;121(5):460-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent and residual juvenile angiofibromas.
  • INTRODUCTION: In the surgical management of juvenile nasopharyngeal angiofibromas the possibility of recurrences and residual tumours is always there.
  • This study was undertaken to predict the prognostic factors determining recurrence of juvenile nasopharyngeal angiofibroma and to find out the usual sites of these tumours.
  • MATERIAL AND METHODS: The medical records of 95 patients with histologically proven juvenile nasopharyngeal angiofibroma were reviewed retrospectively.
  • RESULTS: Complete removal of the juvenile nasopharyngeal angiofibroma was achieved in 78 (82 per cent) of the cases in a single operation.
  • CONCLUSIONS: Extensions into the pterygoid fossa and basisphenoid, erosion of the clivus, intracranial extensions medial to the cavernous sinus, invasion of the sphenoid diploe through a widened pterygoid canal, feeders from the internal carotid artery, a young age and a residual tumour were risk factors found associated with recurrence of juvenile nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Neoplasm Recurrence, Local

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  • (PMID = 17210091.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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18. Porras Alonso EC, Benito Navarro JR, Fernandez Roche JA, Rodriguez Fernández-Freire A: [Child nasopharyngeal angiofibroma]. An Otorrinolaringol Ibero Am; 2005;32(5):483-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Child nasopharyngeal angiofibroma].
  • [Transliterated title] Angiofibroma nasofaringeo infantil.
  • Angiofibromas are benign tumors, highly vascularized, that affect male adolescents and young men.
  • We present a clinical case of an 11-year-old patient with an angiofibroma of the nasopharynx, reviewing the etiopathogenic theories and current surgical approaches.
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / radiography. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / radiography

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  • (PMID = 16318092.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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19. Pradhan B, Thapa N: Juvenile angiofibroma and its management. Nepal Med Coll J; 2009 Sep;11(3):186-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile angiofibroma and its management.
  • This prospective longitudinal study was done to determine extent of tumor and to highlight the importance of lateral rhinotomy approach for nasopharyngeal angiofibroma.
  • Patients with a diagnosis of nasopharyngeal angiofibroma who underwent surgery in Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu from April, 2004 to Jan 2009 were included in the study.
  • Two patients had stage I tumor, 9 patients had stage II disease, other 12 patients had stage III tumor.
  • Most of them had stage III disease and were managed surgically by lateral rhinotomy approach.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 20334067.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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20. Thuesen AD, Jakobsen J, Nepper-Rasmussen J: [Juvenile angiofibroma]. Ugeskr Laeger; 2005 Aug 22;167(34):3163-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile angiofibroma].
  • [Transliterated title] Juvenile angiofibromer.
  • Juvenile angiofibroma is a rare, benign, rich vascular tumor, and approximately one new case is diagnosed in Denmark each year.
  • Through the years, the treatment of juvenile angiofibroma has included many methods, including surgical excision, electrocoagulation, interstitial or external radiation therapy, cryosurgery, hormone administration and chemotherapy.
  • [MeSH-major] Angiofibroma. Nasopharyngeal Neoplasms

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  • [CommentIn] Ugeskr Laeger. 2005 Nov 21;167(47):4482 [16305784.001]
  • (PMID = 16117914.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 25
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21. Giavroglou C, Constantinidis J, Triaridis S, Daniilidis J, Dimitriadis A: [Angiographic evaluation and embolization of juvenile nasopharyngeal angiofibroma]. HNO; 2007 Jan;55(1):36-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiographic evaluation and embolization of juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Juveniles Angiofibrom: Angiographische Diagnostik und präoperative Embolisation.
  • OBJECTIVE: In juvenile nasopharyngeal angiofibroma (JNA), analysis of tumor extension and blood supply is useful for controlling intraoperative bleeding and helps in determining the appropriate surgical approach.
  • [MeSH-major] Angiofibroma / diagnostic imaging. Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / diagnostic imaging. Nasopharyngeal Neoplasms / therapy. Neoplasm Recurrence, Local / prevention & control

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  • (PMID = 16775738.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
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22. Wendler O, Schäfer R, Schick B: Mast cells and T-lymphocytes in juvenile angiofibromas. Eur Arch Otorhinolaryngol; 2007 Jul;264(7):769-75
MedlinePlus Health Information. consumer health - Nasal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mast cells and T-lymphocytes in juvenile angiofibromas.
  • Juvenile angiofibroma (JA) is regarded as a benign fibrovascular tumour of unknown aetiology.
  • Due to its fibrovascular architecture the fibrous and vascular tumour component have been in the focus of most studies.
  • Western blot analysis supported finding of remarkable expression of the mast cell markers tryptase and chymase in JAs and indicated for both proteins similar but also different molecular weights than being observed in NM.
  • Regarding these observations JAs are certainly not only built up by vascular cells and fibrous stroma cells.
  • [MeSH-major] Angiofibroma / pathology. CD4-Positive T-Lymphocytes / pathology. CD8-Positive T-Lymphocytes / pathology. Mast Cells / pathology. Nose Neoplasms / pathology

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  • (PMID = 17310347.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.21.39 / Chymases; EC 3.4.21.59 / Tryptases
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23. Nicolai P, Villaret AB, Farina D, Nadeau S, Yakirevitch A, Berlucchi M, Galtelli C: Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases. Am J Rhinol Allergy; 2010 Mar-Apr;24(2):e67-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases.
  • BACKGROUND: At present, transnasal endoscopic surgery is considered a viable option in the management of small-intermediate size juvenile angiofibromas (JAs).
  • The lesions were classified according to Andrews (Andrews JC, et al., The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach, Laryngoscope 99:429-437, 1989) and Onerci (Onerci M, et al.
  • Juvenile nasopharyngeal angiofibroma: A revised staging system, Rhinology 44:39-45, 2006) staging systems.
  • RESULTS: Lesions were classified as follows: stage I, n = 5; stage II, n = 24; stage IIIa, n = 14; stage IIIb, n = 3 according to Andrews classification system; stage 1, n = 9; stage II, n = 12; stage III, n = 26 according to Onerci's system.
  • In four (8.7%) cases, suspicious residual disease was detected by MRI.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nose Neoplasms / surgery

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  • (PMID = 20338105.001).
  • [ISSN] 1945-8932
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Kapidzić A, Sutalo K: [Surgical treatment of juvenile nasopharyngeal angifibroma]. Med Arh; 2006;60(5):296-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment of juvenile nasopharyngeal angifibroma].
  • [Transliterated title] Operativno lijecenje juvenilnog nazofaringealnog angiofibroma.
  • Juvenile nasopharyngeal angiofibroma represents non-incapsulated benign tumor.
  • Three patients with juvenile nasopharyngeal angiofibroma that underwent surgery in a five year period (2001-2005) at the ENT Clinic of the University Clinical Center in Sarajevo are evaluated in this paper.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 16944730.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] bos
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bosnia and Herzegovina
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25. Sennes LU, Fortes FS, Butugan O, Saldiva PH, Bernardi FC: Tissue maturation correlating to clinical manifestations in juvenile angiofibroma. Ann Otol Rhinol Laryngol; 2005 Sep;114(9):705-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tissue maturation correlating to clinical manifestations in juvenile angiofibroma.
  • OBJECTIVES: Juvenile nasopharyngeal angiofibroma is a rare benign tumor that affects young male patients and shows a characteristic development from its origin.
  • It is not a true neoplasm, but shows features of vascular processes, developing into a more fibrous condition.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 16240934.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Cherekaev VA, Gol'bin DA, Kapitanov DN, Belov AI, Arustamian SR, Gromova VV, Imaev AA: [Surgical treatment of extensive craniofacial juvenile angiofibromas]. Zh Vopr Neirokhir Im N N Burdenko; 2009 Apr-Jun;(2):9-14; discussion 14-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment of extensive craniofacial juvenile angiofibromas].
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor occurring almost exclusively in adolescent and young adult males.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods

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  • (PMID = 19569543.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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27. Tosun F, Onerci M, Durmaz A, Ugurel S: Spontaneous involution of nasopharyngeal angiofibroma. J Craniofac Surg; 2008 Nov;19(6):1686-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous involution of nasopharyngeal angiofibroma.
  • There are several studies addressing regression of residual nasopharyngeal angiofibroma after surgery, but spontaneous regression of this tumor has been reported in only 2 cases.
  • We present a case of nasopharyngeal angiofibroma that has involuted spontaneously in the last 5 years.
  • This is the third reported case in the literature with spontaneous regression of nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 19098582.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Rzaev RM: [The role of angiography in diagnosis and surgical treatment of patients with juvenile angiofibroma of the nasopharynx]. Vestn Otorinolaringol; 2007;(4):18-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The role of angiography in diagnosis and surgical treatment of patients with juvenile angiofibroma of the nasopharynx].
  • 22 of them had juvenile nasopharyngeal angiofibroma (JNA), 8 patients had early cancer.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Angiography / methods. Carotid Arteries / radiography. Nasopharyngeal Neoplasms / diagnosis. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 17828107.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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29. Chistiakova VR, Poliaev IuA, Kovshenkova IuD, Vasil'eva NI, Myl'nikov AA, Pronin AE: [Hemostatic provision of surgical treatment of juvenile angiofibromas of the skull base in children]. Vestn Otorinolaringol; 2006;(1):24-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hemostatic provision of surgical treatment of juvenile angiofibromas of the skull base in children].
  • For three years we operated sixty two 7-16-year-old children for angiofibroma of the base of the skull.
  • Neither lethal outcomes nor complications occurred in children during removal of angiofibromas of the base of the skull.
  • [MeSH-major] Angiofibroma / surgery. Blood Loss, Surgical / prevention & control. Hemostatic Techniques. Hemostatics / therapeutic use. Postoperative Hemorrhage / prevention & control. Skull Base Neoplasms / surgery

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  • (PMID = 16482005.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Hemostatics
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30. Shcherbenko OI, Rodionov MV, Lebedev VA, Kliachkina NB: [Efficacy of remote gamma-therapy in patients with juvenile angiofibroma of the base of the skull]. Vestn Otorinolaringol; 2008;(3):26-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Efficacy of remote gamma-therapy in patients with juvenile angiofibroma of the base of the skull].
  • The results of radiation therapy of 48 patients with juvenile nasopharyngeal angiofibroma were analysed.
  • [MeSH-major] Angiofibroma / radiotherapy. Gamma Rays / therapeutic use. Skull Base Neoplasms / radiotherapy

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  • (PMID = 18833092.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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31. Falkner JA, Falkner JW, Andrews PC: ProteomeCommons.org JAF: reference information and tools for proteomics. Bioinformatics; 2006 Mar 1;22(5):632-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] ProteomeCommons.org JAF: reference information and tools for proteomics.
  • The Java Analysis Framework (JAF) for proteomics provides a freely usable, open-source library of Java code that abstracts all of the aforementioned data, enabling more rapid development of proteomics tools.
  • The JAF also includes several user tools that can be run directly from a web browser.

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  • (PMID = 16434446.001).
  • [ISSN] 1367-4803
  • [Journal-full-title] Bioinformatics (Oxford, England)
  • [ISO-abbreviation] Bioinformatics
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / P41-RR018627
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Proteins
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32. Gramann M, Wendler O, Haeberle L, Schick B: Expression of collagen types I, II and III in juvenile angiofibromas. Cells Tissues Organs; 2009;189(6):403-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of collagen types I, II and III in juvenile angiofibromas.
  • Extracellular matrix components have rarely been the focus of interest in juvenile angiofibroma (JA) studies.
  • [MeSH-major] Angiofibroma / metabolism. Fibrillar Collagens / metabolism

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  • [Copyright] (c) 2008 S. Karger AG, Basel.
  • (PMID = 18815441.001).
  • [ISSN] 1422-6421
  • [Journal-full-title] Cells, tissues, organs
  • [ISO-abbreviation] Cells Tissues Organs (Print)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Fibrillar Collagens
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33. Duerr S, Wendler O, Aigner T, Karosi S, Schick B: Metalloproteinases in juvenile angiofibroma--a collagen rich tumor. Hum Pathol; 2008 Feb;39(2):259-68
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metalloproteinases in juvenile angiofibroma--a collagen rich tumor.
  • MMPs with gelatinase/collagenase activity have not yet been studied in juvenile angiofibroma, a unique fibrovascular tumor with prominent collagen expression.
  • Quantitative real-time polymerase chain reaction studies, Western blot analysis, immunofluorescence studies, gel zymography, and in situ zymography were used to analyze MMP-1, MMP-2, MMP-9, MMP-13, MMP-14, TIMP-1, and TIMP-2 in 9 juvenile angiofibromas and 2 inferior nasal turbinate specimens.
  • Western blot analysis detected more prominent MMP-1, MMP-2, and MMP-9 protein levels in juvenile angiofibromas compared with inferior nasal turbinates, but not MMP-13, MMP-14, TIMP-1, and TIMP-2.
  • Gel zymography indicated increased MMP-2 and MMP-9 gelatinase activity in juvenile angiofibromas compared with inferior nasal turbinates.
  • This study indicates significant expression of MMPs with gelatinase/collagenase activity in juvenile angiofibromas with evidence of a disturbed balance of MMPs to TIMPs toward enhanced MMP activity.
  • [MeSH-major] Angiofibroma / enzymology. Biomarkers, Tumor / metabolism. Collagen / metabolism. Metalloproteases / metabolism. Nose Neoplasms / enzymology

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  • (PMID = 17950779.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Tissue Inhibitor of Metalloproteinase-1; 127497-59-0 / Tissue Inhibitor of Metalloproteinase-2; 9007-34-5 / Collagen; EC 3.4.- / Metalloproteases
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34. Mohindra S, Grover G, Bal AK: Extranasopharyngeal angiofibroma of the nasal septum: a case report. Ear Nose Throat J; 2009 Nov;88(11):E17-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extranasopharyngeal angiofibroma of the nasal septum: a case report.
  • Angiofibroma arising outside the nasopharynx is unusual.
  • The nasal septum is an extremely rare site for the origin of angiofibroma, and to date only 6 such cases previously have been reported in the literature.
  • We report here a case of a 22-year-old man with a vascular mass arising from his nasal septum.
  • The histopathology report was consistent with angiofibroma.
  • We also review other cases in the literature of angiofibroma arising from the nasal septum and discuss a theory of the likely origin of angiofibroma.
  • [MeSH-major] Angiofibroma / diagnosis. Nasal Septum / pathology. Nasopharyngeal Neoplasms / diagnosis. Nose Neoplasms / diagnosis

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  • (PMID = 19924651.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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35. Celik B, Erisen L, Saraydaroglu O, Coskun H: Atypical angiofibromas: a report of four cases. Int J Pediatr Otorhinolaryngol; 2005 Mar;69(3):415-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical angiofibromas: a report of four cases.
  • In this study, our four patients with angiofibroma with various atypical features are presented.
  • 14 patients, diagnosed and treated for angiofibroma in the Otorhinolaryngology Department of Faculty of Medicine in Uludag University between January 1992 and December 2003, have been evaluated.
  • Angiofibromas presenting with at least one of the following criteria such as origin or location other than nasopharynx, presenting complaints other than nasal obstruction or epistaxis, aged younger than seven or older than 25, female sex, atypical histopathology and multifocalitiy were considered as "atypical".
  • Four of 14 angiofibromas (28.5%), which were diagnosed and treated in our clinic, had atypical features.
  • The patients, who have different characteristics other than classical angiofibromas, may be called "Atypical Angiofibroma (AAF)", under the scope of the related literature and our experience.
  • [MeSH-major] Angiofibroma / pathology. Cheek / pathology. Nasopharyngeal Neoplasms / pathology. Nose Neoplasms / pathology. Soft Tissue Neoplasms / pathology. Tonsillar Neoplasms / pathology. Turbinates / pathology

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  • (PMID = 15733604.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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36. Ngan BY, Forte V, Campisi P: Molecular angiogenic signaling in angiofibromas after embolization: implications for therapy. Arch Otolaryngol Head Neck Surg; 2008 Nov;134(11):1170-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular angiogenic signaling in angiofibromas after embolization: implications for therapy.
  • OBJECTIVES: To examine (1) the molecular angiogenic relationship between endothelial and stromal cells of angiofibromas and how this may elucidate the pathogenesis of angiofibromas and (2) the effects of embolization on the expression of angiotrophic factors and proapoptotic and antiapoptotic factors within the tumor.
  • DESIGN: The expression of mesenchymal and endothelial stem/progenitor cell-associated proteins (MECAPs) such as proangiogenic cytokine vascular endothelial growth factor (VEGF), VEGF receptors (VEGFR1, VEGFR2, and VEGFR3), angiopoietin receptors (Tie-1 and Tie-2), and stem cell subset marker CD133 was assessed by immunohistological staining in 7 embolized angiofibroma specimens.
  • Expression of proapoptotic Bax, antiapoptotic Bcl-2 and Bcl-xL, nuclear proliferation protein MiB-1, and hypoxia-inducible factor 1alpha (Hif-1alpha) in peri-ischemic areas of the embolized angiofibromas was also assessed.
  • PATIENTS: Seven patients (identified from medical records, January 1, 2001, through December 31, 2005) who were diagnosed as having juvenile angiofibroma and who underwent surgical treatment.
  • RESULTS: All angiofibroma specimens expressed the stem cell subset marker CD133 and MECAPs except VEGFR3 (a few cases).
  • Specific angiogenesis blockers may represent a novel treatment strategy for angiofibromas.
  • [MeSH-major] Angiofibroma / genetics. Angiofibroma / therapy. Biomarkers, Tumor / genetics. Embolization, Therapeutic. Neoplasm Proteins / genetics. Otorhinolaryngologic Neoplasms / genetics. Otorhinolaryngologic Neoplasms / therapy. Signal Transduction / genetics

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  • (PMID = 19015446.001).
  • [ISSN] 1538-361X
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inducing Agents; 0 / Biomarkers, Tumor; 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Neoplasm Proteins; 0 / Vascular Endothelial Growth Factor A
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37. Durko M, Murlewska A, Gryczyński M, Ratyńska M, Pietruszewska W: [Angiofibroma of the nasal cavity and anterior ethmoid cells--problems in differential diagnosis]. Otolaryngol Pol; 2007;61(5):736-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiofibroma of the nasal cavity and anterior ethmoid cells--problems in differential diagnosis].
  • [Transliterated title] Angiofibroma jamy nosa i komórek sitowych przednich u kobiety--problemy diagnostyki róznicowej.
  • BACKGROUND: Nasal angiofibromas are commonly called juvenile nasal angiofibromas (JNA) because of the almost exclusive occurrence in adolescent males.
  • It is a relatively rare benign fibrovascular tumor originating in the posterior lateral wall of the nasopharynx with only a very few cases diagnosed in females.
  • CASE REPORT: Authors present a case of a 26 y.o. woman with JNA in left nasal cavity with extension to the anterior left ethmoid cells diagnosed and surgically treated at the ENT Department, Medical University of Lodz.
  • CONCLUSION: Although angiofibroma in females is an extremely rare tumor of a sinonasal tract it should be taken into consideration in the differential diagnosis of all nasal cavity tumors (especially solitary fibrous tumor).
  • [MeSH-major] Angiofibroma / pathology. Ethmoid Sinus / pathology. Nose Neoplasms / pathology

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  • (PMID = 18552009.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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38. Yi ZX, Li ZC, Cheng JM, Zhang R, Lin C, Zhou AD, Fan ZM: Huge nasopharyngeal angiofibroma with intracranial extension: change in the dura mater and choice of surgical management. J Laryngol Otol; 2007 Nov;121(11):1108-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Huge nasopharyngeal angiofibroma with intracranial extension: change in the dura mater and choice of surgical management.
  • We aimed to review (1) the imaging changes in the dura mater in cases of huge, lobulated juvenile nasopharyngeal angiofibroma, and (2) the choice of surgical management.
  • Imaging from four cases of juvenile nasopharyngeal angiofibroma showed extrapharyngeal extension of the tumour.
  • [MeSH-major] Angiofibroma / pathology. Dura Mater / radiography. Nasopharyngeal Neoplasms / pathology. Otorhinolaryngologic Surgical Procedures / methods

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  • (PMID = 17295934.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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39. Hernández Monge A, Estrada Moscoso I, Márquez Iribe P, Alanis Fuentes J, Pacheco Pineda R: [Vulvar cellular angiofibroma. A report of a case and bibliographic review]. Ginecol Obstet Mex; 2006 Sep;74(9):499-502
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Vulvar cellular angiofibroma. A report of a case and bibliographic review].
  • [Transliterated title] Angiofibroma celular de la vulva. Comunicación de un caso y revisión de la bibliografía.
  • The vulvar cellular angiofibroma is a rare mesenchymal tumor.
  • Misdiagnosis is common and it can be confounded with spindle cell lipoma, hydrocele of the canal of Nuck, fibromas, angiomyofibroblastoma and many other mesenchymal tumors.
  • [MeSH-major] Angiofibroma / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 17133966.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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40. Bleier BS, Kennedy DW, Palmer JN, Chiu AG, Bloom JD, O'Malley BW Jr: Current management of juvenile nasopharyngeal angiofibroma: a tertiary center experience 1999-2007. Am J Rhinol Allergy; 2009 May-Jun;23(3):328-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Current management of juvenile nasopharyngeal angiofibroma: a tertiary center experience 1999-2007.
  • BACKGROUND: Over the past 10 years, the management of juvenile nasopharyngeal angiofibroma (JNA) has been redefined because of the improvement of transnasal skull base techniques.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 19490810.001).
  • [ISSN] 1945-8924
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. Khalifa MA, Ragab SM: Endoscopic assisted antral window approach for type III nasopharyngeal angiofibroma with infratemporal fossa extension. Int J Pediatr Otorhinolaryngol; 2008 Dec;72(12):1855-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic assisted antral window approach for type III nasopharyngeal angiofibroma with infratemporal fossa extension.
  • OBJECTIVES: To assess the efficacy and safety of endoscopic assisted antral window approach in advanced nasopharyngeal angiofibroma with infratemporal fossa extension.
  • MATERIALS AND METHODS: Sixteen cases diagnosed as juvenile nasopharyngeal angiofibroma type III with infratemporal fossa extension were surgically managed using endoscopic assisted antral window approach (group A) and compared with another group of similar number that were managed using endoscopic assisted midfacial degloving (group B).
  • [MeSH-major] Angiofibroma / surgery. Cranial Fossa, Middle / pathology. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18952302.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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42. Bansal C, Stewart D, Li A, Cockerell CJ: Histologic variants of fibrous papule. J Cutan Pathol; 2005 Jul;32(6):424-8
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  • [Title] Histologic variants of fibrous papule.
  • Fibrous papules (FPs) are common benign lesions usually of the face.
  • [MeSH-major] Angiofibroma / pathology. Facial Neoplasms / pathology. Skin Neoplasms / pathology

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  • (PMID = 15953376.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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43. Dere H, Ozcan KM, Ergul G, Bahar S, Ozcan I, Kulacoglu S: Extranasopharyngeal angiofibroma of the cheek. J Laryngol Otol; 2006 Feb;120(2):141-4
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  • [Title] Extranasopharyngeal angiofibroma of the cheek.
  • Angiofibromas rarely localize in extranasopharyngeal sites.
  • The most common site for extranasopharyngeal angiofibromas is the maxillary sinus.
  • The ethmoid and sphenoid sinuses, nasal septum, middle and inferior turbinates, conjunctiva, molar and retromolar region, and larynx are other sites where extranasopharyngeal angiofibromas have been reported.
  • Only one case of buccal extranasopharyngeal angiofibroma has been reported to date.
  • We present a case of buccal extranasopharyngeal angiofibroma that was excised completely following embolization and we also review the literature.
  • [MeSH-major] Angiofibroma / pathology. Mouth Neoplasms / pathology. Vascular Neoplasms / pathology

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  • (PMID = 16359575.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 13
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44. Cherekaev VA, Belov AI, Kulikovskiĭ PV, Arustamian SR: [Juvenile angiofibroma predominantly extending into the middle cranial fossa and eye-socket]. Zh Vopr Neirokhir Im N N Burdenko; 2006 Jan-Mar;(1):37-9; discussion 39-40

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  • [Title] [Juvenile angiofibroma predominantly extending into the middle cranial fossa and eye-socket].
  • The paper analyzes a rare case of juvenile angiofibroma primarily locating in the infratemporal and middle cranial fossa without a nodule in the nasopharynx.
  • Since the disease has started from right facial hypesthesia, neurinoma involving the first and second branches of the trigeminal nerve and spreading to the eye-socket may be suggested.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Skull Base Neoplasms / diagnosis. Skull Base Neoplasms / surgery

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  • (PMID = 16739934.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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45. Klockars T, Renkonen S, Leivo I, Hagström J, Mäkitie AA: Juvenile nasopharyngeal angiofibroma: no evidence for inheritance or association with familial adenomatous polyposis. Fam Cancer; 2010 Sep;9(3):401-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: no evidence for inheritance or association with familial adenomatous polyposis.
  • Juvenile nasopharyngeal angiofibromas (JNAs) are rare tumors with prominent vascularity and locally destructive growth.
  • Twenty-one patients diagnosed with juvenile angiofibroma filled out a detailed patient questionnaire.
  • No patients reported any relatives with nasopharyngeal angiofibroma or familial adenomatous polyposis.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Angiofibroma / genetics. Genetic Predisposition to Disease. Nasopharyngeal Neoplasms / genetics

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  • (PMID = 20229070.001).
  • [ISSN] 1573-7292
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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46. Pamir MN, Kilic T, Ozek MM, Ozduman K, Türe U: Non-meningeal tumours of the cavernous sinus: a surgical analysis. J Clin Neurosci; 2006 Jul;13(6):626-35
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  • A retrospective analysis of 42 cases of benign non-meningeal tumours of the cavernous sinus operated on at Marmara University between April 1992 and April 2003 is presented.
  • The study cohort consisted of 13 pituitary adenomas, 11 trigeminal schwannomas, seven chordomas, three chondrosarcomas, two juvenile angiofibromas, two epidermoid tumours, one plasmacytoma, one cavernous haemangioma and one internal carotid plexus schwannoma.

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  • (PMID = 16860718.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Scotland
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47. Lehmann M, Ulrich S, Reineke U, Hamberger U, Dietrich U, Sudhoff H: [Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma]. HNO; 2010 Aug;58(8):853-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma].
  • Preoperative embolization for the treatment of juvenile nasopharyngeal angiofibroma was successfully accomplished with Onyx by intratumoral puncture for the first time.
  • Transnasal surgery on the following day achieved complete resection of the angiofibroma without complications.
  • Direct intratumoral embolization of juvenile nasopharyngeal angiofibromas appears to be a safe and effective preoperative method without complications.
  • [MeSH-major] Angiofibroma / blood supply. Angiofibroma / surgery. Dimethyl Sulfoxide. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / blood supply. Nasopharyngeal Neoplasms / surgery. Polyvinyls. Preoperative Care

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  • (PMID = 20596683.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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48. Heinrich UR, Brieger J, Gosepath J, Wierzbicka M, Sokolov M, Roth Y, Szyfter W, Bittinger F, Mann WJ: Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma. Cancer Genet Cytogenet; 2007 Jun;175(2):138-43

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor, mostly affecting adolescent males.
  • No DNA aneuploidy was detected, a finding in accordance with the generally benign characteristics of JNAs.
  • Autosomal gains in the primary tumor should be further evaluated as markers for a potentially increased risk of recurrence after surgical removal in this entity.
  • [MeSH-major] Angiofibroma / genetics. Chromosome Aberrations. Nasopharyngeal Neoplasms / genetics. Neoplasm Recurrence, Local / genetics

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  • (PMID = 17556070.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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49. Kösling S, Knipping S, Hofmockel T: [Imaging of nasopharyngeal diseases]. HNO; 2009 Aug;57(8):813-24; quiz 825
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Imaging of nasopharyngeal diseases].
  • These include nasopharyngeal cysts, lymphoid hyperplasia, juvenile angiofibroma, carcinomas and non-Hodgkin lymphoma.
  • Typical radiological findings, possibilities for making a specific diagnosis, differential diagnosis and description of the spread of a neoplasm are the central points.
  • [MeSH-major] Image Enhancement / methods. Magnetic Resonance Imaging / methods. Nasopharyngeal Diseases / diagnosis. Nasopharynx / diagnostic imaging. Nasopharynx / pathology. Tomography, X-Ray Computed / methods

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  • (PMID = 19639275.001).
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50. Das S, Kirsch CF: Imaging of lumps and bumps in the nose: a review of sinonasal tumours. Cancer Imaging; 2005;5:167-77

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sinonasal disease is one of the most common clinical head and neck pathologies.
  • Although sinus tumours are rare, they portend a poor prognosis, often due to advanced disease at diagnosis.
  • Like most neoplasms, early detection improves prognosis, therefore clinicians and radiologists should be aware of features separating tumours from inflammatory sinus disease.
  • Benign neoplasms reviewed include osteoma, inverting papilloma, and juvenile nasal angiofibroma.

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  • [Copyright] International Cancer Imaging Society.
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  • (PMID = 16361146.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 73
  • [Other-IDs] NLM/ PMC1665243
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51. Val-Bernal JF, Rubio S, Garijo MF, González-Vela MC: Extragenital subcutaneous cellular angiofibroma. Case report. APMIS; 2007 Mar;115(3):254-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extragenital subcutaneous cellular angiofibroma. Case report.
  • Cellular angiofibroma (CAF) is a rare distinctive mesenchymal neoplasm that occurs almost exclusively in the genital area.
  • We report the case of a 38-year-old woman who presented with an asymptomatic subcutaneous mass, 3.5 cm in diameter, located in the left hypochondrium, which had progressively enlarged during the previous 6 months.
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / surgery. Skin Neoplasms / pathology

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  • (PMID = 17367472.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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52. Hosseini SM, Borghei P, Borghei SH, Ashtiani MT, Shirkhoda A: Angiofibroma: an outcome review of conventional surgical approaches. Eur Arch Otorhinolaryngol; 2005 Oct;262(10):807-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiofibroma: an outcome review of conventional surgical approaches.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a benign tumor of the nasopharynx, and for its treatment, many surgical approaches have been recommended.
  • Three of them were disease free, and in two cases residues were demonstrated that were asymptomatic and were chosen only to be observed.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Neoplasm Recurrence, Local / epidemiology. Otorhinolaryngologic Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Child. Disease-Free Survival. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness. Neoplasm Staging. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15739087.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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53. Olubunmi OA: Misdiagnosis of tuberous sclerosis in a Nigerian girl: a case report and review of literature. Ann Afr Med; 2010 Apr-Jun;9(2):95-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tuberous sclerosis is a rare neuro-cutaneous syndrome, one of the phakomatosis, characterized by facial angiofibromas (adenoma sebaceum), mental retardation and epilepsy.
  • [MeSH-minor] Adolescent. Angiofibroma / diagnosis. Anticonvulsants / therapeutic use. Diagnostic Errors. Epilepsy / drug therapy. Epilepsy / etiology. Female. Humans. Intellectual Disability / etiology. Neurofibromatoses / diagnosis. Skin Neoplasms / diagnosis. Tomography, X-Ray Computed. Treatment Outcome. Valproic Acid / therapeutic use

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  • (PMID = 20587932.001).
  • [ISSN] 0975-5764
  • [Journal-full-title] Annals of African medicine
  • [ISO-abbreviation] Ann Afr Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Nigeria
  • [Chemical-registry-number] 0 / Anticonvulsants; 614OI1Z5WI / Valproic Acid
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54. Valencia MP, Castillo M: Congenital and acquired lesions of the nasal septum: a practical guide for differential diagnosis. Radiographics; 2008 Jan-Feb;28(1):205-24; quiz 326
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Inflammatory diseases that may affect the nasal septum include sarcoidosis, reparative granuloma, and Wegener granulomatosis.
  • Last, the tumors that may arise in the nasal septum or may involve it secondarily include carcinomas, Pindborg tumor, sarcoma, angiofibroma, hemangioma, neuroendocrine tumor, and schwannoma.

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  • (PMID = 18203939.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 40
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55. Septer S, Thompson ES, Willemsen-Dunlap A: Anesthesia concerns for children with tuberous sclerosis. AANA J; 2006 Jun;74(3):219-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We describe a 10-year-old girl with TS scheduled to receive a general anesthetic for laser treatment of facial angiofibromas.
  • The patient had several coexisting maladies from TS, including hypertension, autism, seizure disorder, cardiac rhabdomyomas, developmental delay, and bilateral polycystic renal disease.
  • [MeSH-minor] Angiofibroma / etiology. Angiofibroma / surgery. Child. Developmental Disabilities / etiology. Echocardiography. Facial Neoplasms / etiology. Facial Neoplasms / surgery. Female. Genes, Dominant / genetics. Heart Neoplasms / etiology. Heart Neoplasms / ultrasonography. Humans. Hypertension / etiology. Incidence. Laser Therapy. Nursing Assessment. Patient Care Planning. Penetrance. Perioperative Care / methods. Perioperative Care / nursing. Polycystic Kidney Diseases / etiology. Rare Diseases. Rhabdomyoma / etiology. Rhabdomyoma / ultrasonography. Seizures / etiology

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  • (PMID = 16786916.001).
  • [ISSN] 0094-6354
  • [Journal-full-title] AANA journal
  • [ISO-abbreviation] AANA J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 50
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61. Mohammadi M, Saedi B, Basam A: Effect of embolisation on endoscopic resection of angiofibroma. J Laryngol Otol; 2010 Jun;124(6):631-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of embolisation on endoscopic resection of angiofibroma.
  • OBJECTIVE: To determine the effect of embolisation on endoscopic resection of angiofibroma.
  • Twenty-three patients with angiofibroma (nine embolised and 14 not embolised) underwent endoscopic resection between January 2007 and August 2008 in two tertiary referral centres.
  • CONCLUSION: Endoscopic resection is a feasible and safe method for angiofibroma surgery.
  • The current evidence does not support obligatory embolisation in every case of endoscopic angiofibroma resection.
  • [MeSH-major] Angiofibroma / surgery. Blood Loss, Surgical / prevention & control. Embolization, Therapeutic. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 20067650.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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62. Rong Z, Zixiang Y, Chang L, Guoxing X, Sheng Z, Yuanteng X, Zheming F, Zhihong C: Lacrimal hyposecretion: a surgical complication of juvenile nasopharyngeal angiofibroma. Am J Otolaryngol; 2008 Nov-Dec;29(6):367-71

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lacrimal hyposecretion: a surgical complication of juvenile nasopharyngeal angiofibroma.
  • PURPOSE: The aim of this study was to evaluate lacrimal hyposecretion in the surgical management of juvenile nasopharyngeal angiofibroma (JNA) and discuss how to prevent and treat this expected surgical complication.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / adverse effects. Xerophthalmia / etiology

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  • (PMID = 19144296.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Hofbauer GF, Marcollo-Pini A, Corsenca A, Kistler AD, French LE, Wüthrich RP, Serra AL: The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis. Br J Dermatol; 2008 Aug;159(2):473-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis.
  • Tuberous sclerosis complex (TSC) is an autosomal dominant disorder with an incidence of approximately one in 6000.
  • It arises from a genetic abnormality involving either the TSC1 gene on chromosome 9 or the TSC2 gene on chromosome 16.
  • Angiofibroma affects 70-80% of patients with TSC, typically on the face.
  • Immunosuppressive treatment with rapamycin, a specific mTOR inhibitor, initiated because of renal transplantation, reduced facial angiofibroma dramatically.
  • [MeSH-major] Angiofibroma / drug therapy. Facial Neoplasms / drug therapy. Sirolimus / therapeutic use. Skin Neoplasms / drug therapy. Tuberous Sclerosis / complications


64. Glad H, Vainer B, Buchwald C, Petersen BL, Theilgaard SA, Bonvin P, Lajer C, Jakobsen J: Juvenile nasopharyngeal angiofibromas in Denmark 1981-2003: diagnosis, incidence, and treatment. Acta Otolaryngol; 2007 Mar;127(3):292-9

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  • [Title] Juvenile nasopharyngeal angiofibromas in Denmark 1981-2003: diagnosis, incidence, and treatment.
  • CONCLUSIONS: Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor in young males, with a non-negligible potential for recurrence.
  • [MeSH-major] Angiofibroma / diagnosis. Nasopharyngeal Neoplasms / diagnosis

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  • (PMID = 17364367.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
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65. Sun Y, Wu Z: [Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Dec;20(23):1076-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma].
  • OBJECTIVE: To investigate the nature of juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma / metabolism. Endothelial Cells / metabolism. Fibroblast Growth Factors / metabolism. Nasopharyngeal Neoplasms / metabolism. Proliferating Cell Nuclear Antigen / metabolism. Vascular Endothelial Growth Factor A / metabolism

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  • (PMID = 17285972.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 0 / fibroblast growth factor 13; 62031-54-3 / Fibroblast Growth Factors
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66. Mistry RC, Qureshi SS, Gupta S, Gupta S: Juvenile nasopharyngeal angiofibroma: a single institution study. Indian J Cancer; 2005 Jan-Mar;42(1):35-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: a single institution study.
  • BACKGROUND: Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor of adolescent males and there is a paucity of Indian studies on this subject.
  • The age distribution, disease patterns, management approaches and treatment outcomes of patients in the two groups were recorded.
  • RESULTS: The mean age at presentation was 16 years and more than 90% of the patients had Stage III or IV disease.
  • Aggressive re-resection should be done for resectable recurrences reserving radiotherapy for unresectable, recurrent/ residual disease.
  • [MeSH-major] Angiofibroma / epidemiology. Nasopharyngeal Neoplasms / epidemiology. Neoplasm Recurrence, Local / epidemiology

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  • (PMID = 15805690.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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67. Gallia GL, Ramanathan M Jr, Blitz AM, Reh DD: Expanded endonasal endoscopic approach for resection of a juvenile nasopharyngeal angiofibroma with skull base involvement. J Clin Neurosci; 2010 Nov;17(11):1423-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expanded endonasal endoscopic approach for resection of a juvenile nasopharyngeal angiofibroma with skull base involvement.
  • Juvenile nasopharyngeal angiofibromas (JNAs) are rare vascular tumors which arise in the nasopharynx of adolescent males.
  • In this report, we describe a patient with a JNA with skull base involvement who underwent an expanded endonasal endoscopic approach for a complete resection.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasal Cavity / surgery. Nasopharyngeal Neoplasms / surgery. Nasopharynx / surgery. Skull Base Neoplasms / surgery

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20708935.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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68. Satgé D, Vidalo E, Desfarges F, de Geeter B: A third case of cardiac neoplasm in a fetus with Beckwith-Wiedemann syndrome: epicardial angiofibroma. Fetal Diagn Ther; 2005 Jan-Feb;20(1):44-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A third case of cardiac neoplasm in a fetus with Beckwith-Wiedemann syndrome: epicardial angiofibroma.
  • OBJECTIVE: A personal observation of a 20-week-old fetus with Beckwith-Wiedemann syndrome (BWS) presenting epicardial angiofibroma prompted us to evaluate cardiac neoplasms in this genetic condition.
  • [MeSH-major] Angiofibroma / etiology. Beckwith-Wiedemann Syndrome / complications. Fetal Diseases. Heart Neoplasms / etiology. Pericardium
  • [MeSH-minor] Adult. Female. Hamartoma / etiology. Hamartoma / pathology. Heart Diseases / etiology. Heart Diseases / pathology. Humans. Pregnancy. Pregnancy Trimester, First

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  • (PMID = 15608459.001).
  • [ISSN] 1015-3837
  • [Journal-full-title] Fetal diagnosis and therapy
  • [ISO-abbreviation] Fetal. Diagn. Ther.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 15
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69. Huang J, Sacks R, Forer M: Endoscopic resection of juvenile nasopharyngeal angiofibroma. Ann Otol Rhinol Laryngol; 2009 Nov;118(11):764-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic resection of juvenile nasopharyngeal angiofibroma.
  • OBJECTIVES: A 2-surgeon technique has been proposed that allows resection of juvenile nasopharyngeal angiofibroma (JNA) with extension into the infratemporal fossa by utilizing a septal incision for passage of a retracting instrument from the opposite nostril.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 19999360.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Nomura K, Shimomura A, Awataguchi T, Murakami K, Kobayashi T: A case of angiofibroma originating from the inferior nasal turbinate. Auris Nasus Larynx; 2006 Jun;33(2):191-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of angiofibroma originating from the inferior nasal turbinate.
  • Angiofibromas are nasopharyngeal tumors mostly seen in adolescent males.
  • Extranasopharyngeal angiofibromas, although rare, have been reported.
  • We report a case of extranasopharyngeal angiofibroma arising from the inferior turbinate of a 62-year-old male.
  • Previous extranasopharyngeal angiofibromas research was reviewed.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology. Turbinates / pathology

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  • (PMID = 16310998.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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71. Unsal Tuna E, Karaca C, Kaymakçi M, Ozbek C, Ozdem C: [Transpalatal approach in juvenile nasopharyngeal angiofibroma]. Kulak Burun Bogaz Ihtis Derg; 2007;17(1):7-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Transpalatal approach in juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Juvenil nazofarenks anjiyofibromunda transpalatal yaklaşim.
  • OBJECTIVES: Juvenile nasopharyngeal angiofibroma (JNA) cases treated with transpalatal approach were evaluated with respect to localization, complications, intraoperative blood loss, recurrence, and prognosis.
  • RESULTS: Three patients (20%) had Chandler stage II, 11 patients (73%) had stage III, and one patient (7%) had stage IV disease.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Palate / surgery

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  • (PMID = 17483604.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Turkey
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72. Cansiz H, Güvenç MG, Sekercioğlu N: Surgical approaches to juvenile nasopharyngeal angiofibroma. J Craniomaxillofac Surg; 2006 Jan;34(1):3-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical approaches to juvenile nasopharyngeal angiofibroma.
  • INTRODUCTION: Juvenile nasopharyngeal angiofibromas are highly vascular, non-encapsulated tumours affecting predominantly young males.
  • These lesions are benign histologically but they may become life-threatening with excessive bleeding or intracranial extension.
  • MATERIAL AND METHODS: The surgical approaches to 22 male patients with nasopharyngeal angiofibromas are reviewed.
  • CONCLUSION: The suggested treatment of juvenile nasopharyngeal angiofibroma consists of an endoscopic transnasal approach for early stage lesions, and a modified midfacial degloving for almost all of the advanced lesions.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Oral Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Carotid Artery Injuries / etiology. Carotid Artery, Internal / pathology. Child. Craniotomy / adverse effects. Endoscopy. Facial Paralysis / etiology. Frontal Bone / surgery. Humans. Male. Neoplasm Staging. Nose / surgery. Nose Diseases / etiology. Paresthesia / etiology. Postoperative Complications. Retrospective Studies. Rupture. Temporal Bone / surgery. Treatment Outcome

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  • (PMID = 16343920.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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73. Patrocínio JA, Patrocínio LG, Borba BH, Bonatti Bde S, Guimarães AH: Nasopharyngeal angiofibroma in an elderly woman. Am J Otolaryngol; 2005 May-Jun;26(3):198-200

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasopharyngeal angiofibroma in an elderly woman.
  • "Juvenile" nasopharyngeal angiofibroma is a locally aggressive, yet histologically benign, vascular neoplasm.
  • We report a rare case of a 64-year-old woman with a red lobulated mass in the right nostril, diagnosed as nasopharyngeal angiofibroma on postoperative histopathologic and immunohistochemical analysis.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 15858777.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Hackman T, Snyderman CH, Carrau R, Vescan A, Kassam A: Juvenile nasopharyngeal angiofibroma: The expanded endonasal approach. Am J Rhinol Allergy; 2009 Jan-Feb;23(1):95-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: The expanded endonasal approach.
  • BACKGROUND: Juvenile nasopharyngeal angiofibroma (JNA) is a benign but locally aggressively vascular tumor that may involve the skull base and extend intracranially.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods

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  • (PMID = 19379621.001).
  • [ISSN] 1945-8924
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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75. Eloy P, Watelet JB, Hatert AS, de Wispelaere J, Bertrand B: Endonasal endoscopic resection of juvenile nasopharyngeal angiofibroma. Rhinology; 2007 Mar;45(1):24-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endonasal endoscopic resection of juvenile nasopharyngeal angiofibroma.
  • Juvenile angiofibroma (JNA) is a rare benign but locally aggressive tumour of the nasopharynx that primarily occurs in adolescent males.
  • According to Radkowski's classification (Table 1), one patient was stage Ia, one was stage Ib and four patients were stage IIb.
  • All patients but one were free of disease.
  • Based upon the recent international literature, endonasal surgery combined with a preoperative embolization of the arterial supply is indicated for small and middle size JNAs but also for large tumours extended to the pterygopalatine fossa and medial aspect of the infratemporal fossa.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 17432065.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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76. McAfee WJ, Morris CG, Amdur RJ, Werning JW, Mendenhall WM: Definitive radiotherapy for juvenile nasopharyngeal angiofibroma. Am J Clin Oncol; 2006 Apr;29(2):168-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Definitive radiotherapy for juvenile nasopharyngeal angiofibroma.
  • OBJECTIVES: To update our experience with definitive radiotherapy (RT) for juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma / radiotherapy. Nasopharyngeal Neoplasms / radiotherapy

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  • (PMID = 16601437.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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77. Janaki MG, Nirmala S, Rajeev AG: Nasopharyngeal angiofibroma treated with radiotherapy. J Cancer Res Ther; 2007 Apr-Jun;3(2):100-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasopharyngeal angiofibroma treated with radiotherapy.
  • Nasopharyngeal angiofibroma is a rare, highly vascular, benign, locally aggressive tumor, affecting boys of adolescent age.
  • Although surgery is the treatment of choice in early cases, considerable debate exists regarding the treatment of advanced disease with intracranial extension.
  • We are herewith reporting a case of nasopharyngeal angiofibroma who showed complete hemostasis and improvement in vision to radiotherapy.
  • [MeSH-major] Angiofibroma / radiotherapy. Nasopharyngeal Neoplasms / radiotherapy

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  • (PMID = 17998732.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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78. Coutinho-Camillo CM, Brentani MM, Nagai MA: Genetic alterations in juvenile nasopharyngeal angiofibromas. Head Neck; 2008 Mar;30(3):390-400

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic alterations in juvenile nasopharyngeal angiofibromas.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm of the nasopharynx that accounts for 0.5% of all head and neck tumors.
  • Although histologically benign in appearance, JNAs are locally aggressive and destructive, spreading from the nasal cavity to the nasopharynx, paranasal sinuses, and orbit skull base with intracranial extension.
  • [MeSH-major] Angiofibroma / genetics. Nasopharyngeal Neoplasms / genetics

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  • [Copyright] (c) 2008 Wiley Periodicals, Inc. Head Neck, 2008.
  • (PMID = 18228521.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Intercellular Signaling Peptides and Proteins; 0 / RNA, Messenger; 0 / Receptors, Steroid; 0 / beta Catenin; EC 2.5.1.18 / Glutathione Transferase
  • [Number-of-references] 103
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79. Jacyk WK, Rütten A, Requena L: Fibrous papule of the face with granular cells. Dermatology; 2008;216(1):56-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrous papule of the face with granular cells.
  • Fibrous papule of the face is a common benign lesion located most often on the nose.
  • It presents usually as a single small, firm, skin-coloured papule and is often misdiagnosed as melanocytic naevus, wart or small nodular basal cell carcinoma.
  • Uncommon histopathologic variants of fibrous papule of the face include hypercellular, clear-cell, pleomorphic, pigmented, inflammatory and granular-cell types.
  • We present here a patient with the syndrome of familial cancer and fibrous papule of the face with granular cells.
  • Probably the occurrence of the granular-cell fibrous papule of the face was coincidental.
  • [MeSH-major] Angiofibroma / pathology. Facial Neoplasms / pathology. Skin Neoplasms / pathology

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  • [Copyright] (c) 2008 S. Karger AG, Basel.
  • [CommentIn] Dermatology. 2008;217(1):56-7; author reply 57 [18382105.001]
  • (PMID = 18032900.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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80. Moorthy PN, Ranganatha Reddy B, Qaiyum HA, Madhira S, Kolloju S: Management of juvenile nasopharyngeal angiofibroma: a five year retrospective study. Indian J Otolaryngol Head Neck Surg; 2010 Oct;62(4):390-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of juvenile nasopharyngeal angiofibroma: a five year retrospective study.
  • Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck region typically affecting adolescent boys.
  • The present article is a retrospective study of surgically treated patients of juvenile nasopharyngeal angiofibroma over a period of 5 years.
  • The study discusses about most common presenting complaints, correlation of preoperative radiological and intraoperative staging and factors affecting recurrence of juvenile nasopharyngeal angiofibroma.

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  • (PMID = 22319699.001).
  • [ISSN] 0973-7707
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3266082
  • [Keywords] NOTNLM ; Angiofibroma / Nasopharynx / Neoplasm staging / Recurrence
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81. Tosun F, Ozer C, Gerek M, Yetiser S: Surgical approaches for nasopharyngeal angiofibroma: comparative analysis and current trends. J Craniofac Surg; 2006 Jan;17(1):15-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical approaches for nasopharyngeal angiofibroma: comparative analysis and current trends.
  • This study presents a comparative analysis of current surgical approaches for the treatment of nasopharyngeal angiofibroma, including extension of tumors, postoperative morbidity, complications, and recurrence rate.
  • Twenty-four patients who underwent surgery with the diagnosis of juvenile nasopharyngeal angiofibroma at our department between 1993 and 2003 were retrospectively reviewed according to their clinical presentation, surgical approaches, and prognosis.
  • In this regard, the transnasal endoscopic approach can be used successfully in place of the transpalatal approach due to the former's lesser surgical morbidity and wide lateral exposure of the field in patients with nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Endoscopy. Follow-Up Studies. Humans. Male. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Nose / surgery. Nose Diseases / etiology. Oral Fistula / etiology. Palate / surgery. Postoperative Complications. Prognosis. Retrospective Studies

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  • (PMID = 16432402.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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82. Sun W, Huang X, Zheng Y, Peng J, Zou H: [Resection of nasopharyngeal angiofibroma using by midfacial degloving approach and modified maxillectomy]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2007 Dec;21(24):1134-5, 1139

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Resection of nasopharyngeal angiofibroma using by midfacial degloving approach and modified maxillectomy].
  • OBJECTIVE: To explore the feasibility of treatment on angiofibroma patients with stage III, IV by midfacial degloving approach and modified maxillectomy.
  • 2004, midfacial degloving approach and modified maxillectomy was used for treating 7 angiofibroma patients with stage III, IV.
  • The pathology of 7 cases was nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / surgery. Maxilla / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18330264.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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83. Korcum AF, Ağirdir BV, Aksu G, Güney K, Dinç O: [Treatment modalities of nasopharyngeal angiofibroma]. Kulak Burun Bogaz Ihtis Derg; 2008 Jul-Aug;18(4):263-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment modalities of nasopharyngeal angiofibroma].
  • Nasopharyngeal angiofibroma is a rare, benign vascular tumor originating from the sphenopalatine foramen.
  • Many treatment modalities have been used for the management of nasopharyngeal angiofibroma, but surgery and external beam radiation therapy have proved to be the only effective treatment modalities with acceptable morbidity.
  • [MeSH-major] Angiofibroma / radiotherapy. Angiofibroma / surgery. Nasopharyngeal Neoplasms / radiotherapy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 19052499.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 39
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84. Onerci M, Gumus K, Cil B, Eldem B: A rare complication of embolization in juvenile nasopharyngeal angiofibroma. Int J Pediatr Otorhinolaryngol; 2005 Mar;69(3):423-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare complication of embolization in juvenile nasopharyngeal angiofibroma.
  • Juvenile nasopharyngeal angiofibroma (JNA) is one of the most common benign nasal cavity tumors of adolescence.
  • It exhibits a strong tendency to bleed and despite being microscopically benign, its behavior is locally aggressive.
  • In this article, a young male with juvenile nasopharyngeal angiofibroma, who lost his vision in the left eye following embolization was presented and the possible therapeutic options in such a complication were discussed.
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / therapy

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  • (PMID = 15733605.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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85. Ahmad R, Ishlah W, Azilah N, Rahman JA: Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization. Asian J Surg; 2008 Oct;31(4):174-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm that occurs almost exclusively in the nasopharynx of adolescent males.

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  • (PMID = 19010758.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] China
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86. Li Z, Lin G, He L, Yi Z: [Perioperative managements of huge lobulated nasopharyngeal angiofibromas with intracranial extensions]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Jul;22(14):639-41
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  • [Title] [Perioperative managements of huge lobulated nasopharyngeal angiofibromas with intracranial extensions].
  • OBJECTIVE: To summarize our experience of successful and failed management in 8 huge lobulated nasopharyngeal angiofibromas with intracranial extensions, and introduce some key points of perioperative treatments.
  • [MeSH-major] Angiofibroma / surgery. Brain Neoplasms / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18841793.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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87. Riggs S, Orlandi RR: Juvenile nasopharyngeal angiofibroma recurrence associated with exogenous testosterone therapy. Head Neck; 2010 Jun;32(6):812-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma recurrence associated with exogenous testosterone therapy.
  • BACKGROUND: Juvenile nasopharyngeal angiofibromas (JNAs) are rare benign lesions that express hormonal receptors.
  • This report describes a recurrence of a JNA 20 years after excision associated with exogenous testosterone therapy.
  • METHODS: A 36-year-old man developed a sphenoid mass 20 years following resection of a JNA, shortly after initiating exogenous testosterone therapy for symptomatic low endogenous testosterone.
  • [MeSH-major] Angiofibroma / physiopathology. Nasopharyngeal Neoplasms / physiopathology. Neoplasms, Second Primary / physiopathology. Paranasal Sinus Neoplasms / physiopathology. Sphenoid Sinus. Testosterone / physiology

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  • [Copyright] (c) 2009 Wiley Periodicals, Inc. Head Neck, 2010.
  • (PMID = 19626637.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 3XMK78S47O / Testosterone
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88. Midilli R, Karci B, Akyildiz S: Juvenile nasopharyngeal angiofibroma: analysis of 42 cases and important aspects of endoscopic approach. Int J Pediatr Otorhinolaryngol; 2009 Mar;73(3):401-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: analysis of 42 cases and important aspects of endoscopic approach.
  • OBJECTIVE: To determine the general characteristics of 42 patients who were operated for juvenile nasopharyngeal angiofibroma (JNA); and to determine the important aspects and the advantages of endoscopic transnasal approach over other techniques.
  • Seventeen percent of the patients had referred with recurrent diseases.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures

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  • (PMID = 19124161.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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89. Li Z, Lin C, Lin G, Fang Z, Zhang H, Chen M, Zhou A, Lan S, Yi Z: [Study and analysis on the hemorrhage of pterygoid venous plexus in large nasopharyngeal angiofibroma resection]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Mar;24(6):244-6, 249

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Study and analysis on the hemorrhage of pterygoid venous plexus in large nasopharyngeal angiofibroma resection].
  • OBJECTIVE: To our knowledge, study of the intraoperative profuse bleeding of pterygoid venous plexus (PVP) in large nasopharyngeal angiofibroma resection has not yet been reported.
  • Twenty-six of 44 cases were large nasopharyngeal angiofibromas according to the Fisch classification system(Fisch type III 16, type IV 10).
  • Factors influencing intraoperative bleeding of 26 large nasopharyngeal angiofibroma resections were analyzed retrospectively.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Veins / surgery

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  • (PMID = 20518285.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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90. Gupta AK, Rajiniganth MG, Gupta AK: Endoscopic approach to juvenile nasopharyngeal angiofibroma: our experience at a tertiary care centre. J Laryngol Otol; 2008 Nov;122(11):1185-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic approach to juvenile nasopharyngeal angiofibroma: our experience at a tertiary care centre.
  • OBJECTIVE: To evaluate the efficacy of endoscopic exposure and excision for juvenile nasopharyngeal angiofibroma.
  • DESIGN: Prospective analysis of the outcomes of endoscopic removal of the angiofibroma at a tertiary care centre, using endoscopic and radiological parameters.
  • SUBJECTS: Twenty-eight consecutive patients with angiofibroma were included.
  • CONCLUSION: Endoscopic exposure and excision of angiofibroma was found to be effective.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Head and Neck Neoplasms / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18394208.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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91. Farmer JP, Lamba M, McDonald H, Commons AS: Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis. Can J Ophthalmol; 2006 Apr;41(2):216-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis.
  • CASE REPORT: A 57-year-old woman presented with a 16-month history of a slowly growing mass in the medial aspect of her right lower eyelid.
  • Histopathologic examination revealed a giant cell angiofibroma, which was subsequently excised.
  • COMMENTS: Giant cell angiofibroma is a benign spindle cell neoplasm characterized by multinucleated giant cells and pseudovascular spaces with a propensity to occur in the anterior soft tissues of the orbit of middle-aged adults.
  • It is part of a wide differential diagnosis of tumours that can be separated by various histologic and immunohistochemical features, which are discussed in the report.

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  • (PMID = 16767212.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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92. Tsai CJ, Wang HM, Lu IC, Tai CF, Wang LF, Soo LY, Lu DV: Seizure after local anesthesia for nasopharyngeal angiofibroma. Kaohsiung J Med Sci; 2007 Feb;23(2):97-100
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Seizure after local anesthesia for nasopharyngeal angiofibroma.
  • We report a young male patient who experienced seizure after local injection of 3 mL 2% lidocaine with epinephrine 1:200,000 around a recurrent nasal angiofibroma.
  • [MeSH-major] Anesthesia, Local / adverse effects. Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Seizures / etiology

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  • (PMID = 17339174.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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93. Szymańska A, Korobowicz E, Gołabek W: A rare case of nasopharyngeal angiofibroma in an elderly female. Eur Arch Otorhinolaryngol; 2006 Jul;263(7):657-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of nasopharyngeal angiofibroma in an elderly female.
  • Nasopharyngeal angiofibromas occur predominantly in males in their puberty and adolescence; the incidence in other age groups and in women is exceptional.
  • This report describes a case of a 57-year-old woman with nasopharyngeal angiofibroma presenting typical radiological findings in computed tomography, MR imaging and angiography.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Nasopharyngeal Neoplasms / diagnosis. Nasopharyngeal Neoplasms / surgery
  • [MeSH-minor] Disease-Free Survival. Female. Follow-Up Studies. Humans. Magnetic Resonance Angiography. Middle Aged. Otorhinolaryngologic Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 16625398.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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94. Canales BK, Weiland D, Hoffman N, Slaton J, Tran M, Manivel JC, Monga M: Angiomyofibroblastoma-like tumors (cellular angiofibroma). Int J Urol; 2006 Feb;13(2):177-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomyofibroblastoma-like tumors (cellular angiofibroma).
  • Angiomyofibroblastoma-like tumor (cellular angiofibroma) is a rare, circumscribed, slow-growing mesenchymal tumor that occurs predominantly in the vulva, perineum, and pelvis of women.
  • [MeSH-major] Angiofibroma / pathology. Genital Neoplasms, Male / pathology. Scrotum. Spermatic Cord

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  • (PMID = 16563146.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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95. Belmar P, Boixeda P, Baniandrés O, Fernández-Lorente M, Arrazola JM: [Long-term follow up of angiofibromas treated with CO2 laser in 23 patients with tuberous sclerosis]. Actas Dermosifiliogr; 2005 Oct;96(8):498-503
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  • [Title] [Long-term follow up of angiofibromas treated with CO2 laser in 23 patients with tuberous sclerosis].
  • [Transliterated title] Seguimiento a largo plazo de angiofibromas tratados con láser de CO2 en 23 pacientes con esclerosis tuberosa.
  • INTRODUCTION: Tuberous sclerosis is an autosomal dominant disease in which hamartomas form in multiple organs.
  • Cutaneous changes are one of the primary characteristics of this disease.
  • These include angiofibromas (AF), a common form of presentation that causes significant cosmetic and medical problems.
  • The aim of our study is to assess the long-term response of the treatment of angiofibromas.
  • METHODS: A retrospective study was carried out on 23 patients with angiofibromas treated with CO2 laser.
  • We classified the angiofibromas by size, initial treatment results and patients' ages (< 20 years and 20 years or older).
  • After treatment, patients were followed up for a period of six months to 10 years.
  • When we analyzed the long-term results by the size of the angiofibromas, initial result and patients' ages, we found no statistically significant differences among the different groups.
  • [MeSH-major] Angiofibroma / complications. Angiofibroma / surgery. Laser Therapy. Skin Neoplasms / complications. Skin Neoplasms / surgery. Tuberous Sclerosis / complications

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  • (PMID = 16476284.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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96. Prabhu S, Mahesh KP: Tuberous sclerosis with oral angiofibroma: case report. Br J Oral Maxillofac Surg; 2010 Apr;48(3):205-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tuberous sclerosis with oral angiofibroma: case report.
  • Tuberous sclerosis is a multisystem disorder characterised by the formation of hamartomas in various parts of the body.
  • We present a patient who presented with facial angiofibromas (adenoma sebaceum), shagreen patches, and epileptic seizures.
  • Oral papules showed histological features of angiofibroma, which was peculiar to this case.
  • [MeSH-major] Angiofibroma / pathology. Facial Neoplasms / pathology. Mouth Neoplasms / pathology. Tuberous Sclerosis / pathology

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  • [Copyright] 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 19640621.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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97. Tardío JC: Leiomyomatous nodules in a cellular angiofibroma: a hitherto unreported finding. Virchows Arch; 2009 May;454(5):595-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Leiomyomatous nodules in a cellular angiofibroma: a hitherto unreported finding.
  • Cellular angiofibroma is a benign tumor of the superficial soft tissues of the vulvovaginal and inguinoscrotal regions of adult patients.
  • The case of a 44-year-old female with a perineal cellular angiofibroma containing small leiomyomatous nodules is described in this case report.
  • These nodules could probably be originated from smooth muscle differentiation of the spindle cell component of an otherwise conventional cellular angiofibroma.
  • To our knowledge, the finding of distinct leiomyomatous nodules within a cellular angiofibroma has not been previously reported.
  • [MeSH-major] Angiofibroma / pathology. Leiomyoma / pathology. Neoplasms, Multiple Primary / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19301032.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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98. Weiss ET, Geronemus RG: New technique using combined pulsed dye laser and fractional resurfacing for treating facial angiofibromas in tuberous sclerosis. Lasers Surg Med; 2010 Jul;42(5):357-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] New technique using combined pulsed dye laser and fractional resurfacing for treating facial angiofibromas in tuberous sclerosis.
  • BACKGROUND AND OBJECTIVE: Tuberous sclerosis (TS) is a well-described genetic disorder that is classically associated with up to hundreds of facial angiofibromas.
  • STUDY DESIGN/PATIENTS AND METHODS: We report a combinatorial technique for treating the angiofibromas of TS.
  • RESULTS: In all presented cases, improvement in the number and appearance of facial angiofibromas and erythema is noted.
  • CONCLUSION: The technique of electrosurgery, pulsed-dye laser treatment, and AFR represents a new and safe therapeutic option for treating facial angiofibromas associated with TS.
  • [MeSH-major] Angiofibroma / etiology. Angiofibroma / surgery. Facial Neoplasms / etiology. Facial Neoplasms / surgery. Laser Therapy / methods. Lasers, Dye / therapeutic use. Skin Neoplasms / etiology. Skin Neoplasms / surgery. Tuberous Sclerosis / complications

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  • (PMID = 20583249.001).
  • [ISSN] 1096-9101
  • [Journal-full-title] Lasers in surgery and medicine
  • [ISO-abbreviation] Lasers Surg Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Saylam G, Yücel OT, Sungur A, Onerci M: Proliferation, angiogenesis and hormonal markers in juvenile nasopharyngeal angiofibroma. Int J Pediatr Otorhinolaryngol; 2006 Feb;70(2):227-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proliferation, angiogenesis and hormonal markers in juvenile nasopharyngeal angiofibroma.
  • OBJECTIVES: Juvenile nasopharyngeal angiofibroma (JNA) is a highly vascular and locally invasive tumor that exclusively affects male adolescents.
  • [MeSH-major] Angiofibroma / metabolism. Nasopharyngeal Neoplasms / metabolism. Neoplasm Recurrence, Local / metabolism

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  • (PMID = 16023739.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 0 / Transforming Growth Factor beta; 0 / Vascular Endothelial Growth Factor A
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100. Eloy P, Bachy V, Grulois V, Bertrand B: Pyocele of the lachrymal sac: A late and unusual complication after surgery for a juvenile nasopharyngeal angiofibroma. Clin Ophthalmol; 2008 Mar;2(1):211-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pyocele of the lachrymal sac: A late and unusual complication after surgery for a juvenile nasopharyngeal angiofibroma.
  • JNA (Juvenile nasopharyngeal angiofibroma) is a benign but highly vascular and aggressive tumor that takes its origin in the basisphenoid region close to the sphenopalatine foramen.
  • The authors report a case of a pyocele of the lachrymal sac occurring 60 years after a transantral surgery for a JNA.
  • This case confirms the necessity of a long follow-up for all the patients who had a transantral surgery with resection of the medial wall of the maxillary sinus and dissection of the nasolacrymal duct.

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  • [Cites] Laryngoscope. 2005 Jul;115(7):1201-7 [15995507.001]
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  • (PMID = 19668408.001).
  • [ISSN] 1177-5467
  • [Journal-full-title] Clinical ophthalmology (Auckland, N.Z.)
  • [ISO-abbreviation] Clin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC2698692
  • [Keywords] NOTNLM ; JNA / complication / endonasal DCR / navigation system / pyocele of the lachrymal sac / surgery for JNA
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