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1. Tyagi I, Syal R, Goyal A: Staging and surgical approaches in large juvenile angiofibroma--study of 95 cases. Int J Pediatr Otorhinolaryngol; 2006 Sep;70(9):1619-27
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  • [Title] Staging and surgical approaches in large juvenile angiofibroma--study of 95 cases.
  • INTRODUCTION: Surgery has been the treatment of choice for juvenile nasopharyngeal angiofibroma (JNA) and selection of proper surgical approach depends primarily upon the extensions of the tumor.
  • Lazy S incision was used and combined transmaxillary and transpalatal removal of angiofibroma was done in most of the cases.
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / surgery. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 16777240.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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2. Hofbauer GF, Marcollo-Pini A, Corsenca A, Kistler AD, French LE, Wüthrich RP, Serra AL: The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis. Br J Dermatol; 2008 Aug;159(2):473-5
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  • [Title] The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis.
  • Tuberous sclerosis complex (TSC) is an autosomal dominant disorder with an incidence of approximately one in 6000.
  • It arises from a genetic abnormality involving either the TSC1 gene on chromosome 9 or the TSC2 gene on chromosome 16.
  • Angiofibroma affects 70-80% of patients with TSC, typically on the face.
  • Immunosuppressive treatment with rapamycin, a specific mTOR inhibitor, initiated because of renal transplantation, reduced facial angiofibroma dramatically.
  • [MeSH-major] Angiofibroma / drug therapy. Facial Neoplasms / drug therapy. Sirolimus / therapeutic use. Skin Neoplasms / drug therapy. Tuberous Sclerosis / complications


3. Nzegwu MA, Uguru C, Okafor OC, Ifeoma O, Olusina D: Patterns of oral and jaw tumours seen in eastern Nigeria: a review of sixty cases seen over a 5-year period--1 January 2000 to 31 December 2004. Eur J Cancer Care (Engl); 2008 Nov;17(6):532-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sixty oral and jaw tumours were received out of a total of 4500 specimens constituting 1.3% of all biopsies.
  • The categories were calcifying odontogenic cysts and fibromas 11 (18.3%).
  • Fibrous dysplasia seven (11.7%).
  • Butyroid rhabdomyosarcoma, adenoid cystic carcinoma angiofibroma, fibrous histiocytoma and fibrosarcoma were each one (1.7%).
  • The most common subtype seen were the dentigerous cysts/fibromas, followed by ameloblastomas.

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  • (PMID = 18754768.001).
  • [ISSN] 1365-2354
  • [Journal-full-title] European journal of cancer care
  • [ISO-abbreviation] Eur J Cancer Care (Engl)
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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4. Qian YW, Malliah R, Lee HJ, Das K, Mirani N, Hameed M: A t(12;17) in an extraorbital giant cell angiofibroma. Cancer Genet Cytogenet; 2006 Mar;165(2):157-60
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  • [Title] A t(12;17) in an extraorbital giant cell angiofibroma.
  • We report a case of a 43-year-old male who presented with a large soft-tissue neck mass 7 years ago.
  • A diagnosis of giant cell angiofibroma (GCA) was made on the basis of light microscopy and immunohistochemical studies.
  • This cytogenetic abnormality in GCA is different from the t(17;22)(q22;q13) found in related lesions, such as giant cell fibroblastoma and solitary fibrous tumor, none of which has a specific chromosomal abnormality.
  • [MeSH-major] Angiofibroma / genetics. Chromosomes, Human, Pair 12. Chromosomes, Human, Pair 17. Head and Neck Neoplasms / genetics. Translocation, Genetic

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  • [Copyright] 2006 Elsevier Inc. All rights reserved.
  • (PMID = 16527610.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Finis D, Gümbel H: [Central retinal artery occlusion after embolization in juvenile nasopharyngeal angiofibroma]. Klin Monbl Augenheilkd; 2009 Jul;226(7):579-80
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  • [Title] [Central retinal artery occlusion after embolization in juvenile nasopharyngeal angiofibroma].
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic / adverse effects. Nasopharyngeal Neoplasms / therapy. Retinal Artery Occlusion / etiology. Retinal Artery Occlusion / surgery

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  • (PMID = 19644808.001).
  • [ISSN] 1439-3999
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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6. Hunt CH, Morris JM, Lee PU, Cloft H: Progressive epistaxis in two young males: Classic presentations of juvenile nasopharyngeal angiofibroma in unusual locations. Neuroradiology; 2010 May;52(5):419-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Progressive epistaxis in two young males: Classic presentations of juvenile nasopharyngeal angiofibroma in unusual locations.
  • [MeSH-major] Angiofibroma / diagnostic imaging. Epistaxis / etiology. Nasopharyngeal Neoplasms / diagnostic imaging

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  • [Cites] Ann Surg. 1948 Mar;127(3):513-36 [17859097.001]
  • [Cites] Laryngoscope. 1992 Aug;102(8):928-33 [1323003.001]
  • [Cites] Indian J Dent Res. 2004 Oct-Dec;15(4):145-8 [16035644.001]
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  • [Cites] Int J Pediatr Otorhinolaryngol. 2006 Sep;70(9):1619-27 [16777240.001]
  • (PMID = 20127084.001).
  • [ISSN] 1432-1920
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
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7. Koo PJ, Goykhman I, Lembert L, Nunes LW: MRI features of cellular angiomyofibroma with pathologic correlation. J Magn Reson Imaging; 2009 May;29(5):1195-8
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  • Within the spectrum of extratesticular mesenchymal tumors in the scrotum and perineum lies cellular angiofibroma, also known as angiomyofibroblastoma-like tumor, a rare lesion originally described to almost exclusively occur in the vulva, perineum, and pelvis of women.
  • We present the MRI features of cellular angiofibroma that are consistent with the pathological characteristics of this entity-a benign cellular and fibrous tumor with prominent vascularity.

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  • (PMID = 19388110.001).
  • [ISSN] 1053-1807
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Onerci M, Oğretmenoğlu O, Yücel T: Juvenile nasopharyngeal angiofibroma: a revised staging system. Rhinology; 2006 Mar;44(1):39-45
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: a revised staging system.
  • METHODS: The medical records of 36 patients, all of whom underwent resection of juvenile nasopharyngeal angiofibroma by external or endonasal approach between 1983 and 2002, were reviewed retrospectively.
  • Tumour extent, sites and rate of persistent disease were analyzed and compared with the literature.
  • RESULTS: Persistent or recurrent disease was found in 12 of the 36 patients (33%).
  • Involvement of the pterygoid process base was observed in only 3 of the 24 patients without persistent disease, whereas it was found 10 out of 12 patients with persistent disease.
  • CONCLUSIONS: Advances in radiographic imaging, embolization, and surgical methods of treating angiofibromas have changed the sites associated with a high risk for persistent disease or morbidity.
  • In the light of all these recent advances, data from our series, and the literature, we suggested a new classification for determining the risk of persistent disease, choosing the appropriate surgical method, and for maintaining uniformity.
  • [MeSH-minor] Adolescent. Angiofibroma. Humans. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Neoplasm Staging. Neoplasm, Residual. Paranasal Sinus Neoplasms / pathology. Paranasal Sinus Neoplasms / radiography. Paranasal Sinus Neoplasms / surgery. Tomography, X-Ray Computed

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  • (PMID = 16550949.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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9. Coutinho-Camillo CM, Brentani MM, Nagai MA: Genetic alterations in juvenile nasopharyngeal angiofibromas. Head Neck; 2008 Mar;30(3):390-400
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic alterations in juvenile nasopharyngeal angiofibromas.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm of the nasopharynx that accounts for 0.5% of all head and neck tumors.
  • Although histologically benign in appearance, JNAs are locally aggressive and destructive, spreading from the nasal cavity to the nasopharynx, paranasal sinuses, and orbit skull base with intracranial extension.
  • [MeSH-major] Angiofibroma / genetics. Nasopharyngeal Neoplasms / genetics

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  • [Copyright] (c) 2008 Wiley Periodicals, Inc. Head Neck, 2008.
  • (PMID = 18228521.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Intercellular Signaling Peptides and Proteins; 0 / RNA, Messenger; 0 / Receptors, Steroid; 0 / beta Catenin; EC 2.5.1.18 / Glutathione Transferase
  • [Number-of-references] 103
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10. Wosnitzer B, Gadiraju R: The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1). Radiol Case Rep; 2010;5(4):452
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  • Multiple endocrine neoplasia 1 (MEN 1) is a rare genetic disorder classically characterized by a predisposition to tumors of the parathyroid glands, anterior pituitary gland, and pancreatic islet cells (1).
  • In addition to exhibiting these characteristic tumors, MEN 1 patients also have an increased propensity for other tumors such as carcinoids, adrenal adenomas, angiofibromas, and lipomas (1, 2, 3).
  • The tumors of MEN 1 are usually benign; however, malignancy of some carcinoid, islet cell, and gastrointestinal tract tumors can cause mortality (5, 6, 7, 8).

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  • (PMID = 27307880.001).
  • [ISSN] 1930-0433
  • [Journal-full-title] Radiology case reports
  • [ISO-abbreviation] Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4901017
  • [Keywords] NOTNLM ; CT, computed tomography / EGD, esophagogastroduodenoscopy / MEN 1, multiple endocrine neoplasia 1 / MRI, magnetic resonance imaging
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11. Scott MT, Roper M, Mura J: Vertebral artery reconstruction using microanastomosis and intraoperative neuromonitoring: a case report from Santiago, Chile. Am J Electroneurodiagnostic Technol; 2008 Jun;48(2):79-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The preliminary result of the biopsy was an angiofibroma.

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  • (PMID = 18680896.001).
  • [ISSN] 1086-508X
  • [Journal-full-title] American journal of electroneurodiagnostic technology
  • [ISO-abbreviation] Am J Electroneurodiagnostic Technol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Pamir MN, Kilic T, Ozek MM, Ozduman K, Türe U: Non-meningeal tumours of the cavernous sinus: a surgical analysis. J Clin Neurosci; 2006 Jul;13(6):626-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A retrospective analysis of 42 cases of benign non-meningeal tumours of the cavernous sinus operated on at Marmara University between April 1992 and April 2003 is presented.
  • The study cohort consisted of 13 pituitary adenomas, 11 trigeminal schwannomas, seven chordomas, three chondrosarcomas, two juvenile angiofibromas, two epidermoid tumours, one plasmacytoma, one cavernous haemangioma and one internal carotid plexus schwannoma.

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  • (PMID = 16860718.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Scotland
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13. Cole RP, Widdowson D, Moore JC: Outcome of erbium:yttrium aluminium garnet laser resurfacing treatments. Lasers Med Sci; 2008 Oct;23(4):427-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Erbium:yttrium aluminium garnet (erbium:YAG) laser treatment was used to resurface skin abnormalities in patients suffering from conditions that included epidermal naevi, tuberous sclerosis, angiofibromata, neurofibromatosis, and scarring caused by acne or other means.
  • [MeSH-major] Laser Therapy / instrumentation. Lasers, Solid-State. Skin Diseases / surgery

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  • (PMID = 18074165.001).
  • [ISSN] 0268-8921
  • [Journal-full-title] Lasers in medical science
  • [ISO-abbreviation] Lasers Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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14. Micheletti AM, Silva AC, Nascimento AG, Da Silva CS, Murta EF, Adad SJ: Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study. Sao Paulo Med J; 2005 Sep 1;123(5):250-2
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  • [Title] Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study.
  • CONTEXT: Cellular angiofibroma of the vulva is a rare tumor that was first described in 1997.
  • The differential diagnoses for this tumor include aggressive angiomyxoma, angiomyofibroblastoma, lipoma of fusiform cells, solitary fibrous tumor, perineurioma and leiomyoma.
  • [MeSH-major] Angiofibroma / diagnosis. Bartholin's Glands. Cysts / diagnosis. Vulvar Neoplasms / diagnosis

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  • (PMID = 16358102.001).
  • [ISSN] 1516-3180
  • [Journal-full-title] São Paulo medical journal = Revista paulista de medicina
  • [ISO-abbreviation] Sao Paulo Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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15. Korcum AF, Ağirdir BV, Aksu G, Güney K, Dinç O: [Treatment modalities of nasopharyngeal angiofibroma]. Kulak Burun Bogaz Ihtis Derg; 2008 Jul-Aug;18(4):263-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment modalities of nasopharyngeal angiofibroma].
  • Nasopharyngeal angiofibroma is a rare, benign vascular tumor originating from the sphenopalatine foramen.
  • Many treatment modalities have been used for the management of nasopharyngeal angiofibroma, but surgery and external beam radiation therapy have proved to be the only effective treatment modalities with acceptable morbidity.
  • [MeSH-major] Angiofibroma / radiotherapy. Angiofibroma / surgery. Nasopharyngeal Neoplasms / radiotherapy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 19052499.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 39
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16. Schwartz RA, Fernández G, Kotulska K, Jóźwiak S: Tuberous sclerosis complex: advances in diagnosis, genetics, and management. J Am Acad Dermatol; 2007 Aug;57(2):189-202
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The classic triad is seizures, mental retardation, and cutaneous angiofibromas.
  • [MeSH-minor] Diagnosis, Differential. Humans. Molecular Diagnostic Techniques. Mutation. Protein Kinases / drug effects. Protein Kinases / metabolism. Sirolimus / therapeutic use. Skin Diseases / etiology. Skin Diseases / pathology. TOR Serine-Threonine Kinases. Tooth Diseases / etiology. Tooth Diseases / pathology


17. Ramezani A, Haghighatkhah H, Moghadasi H, Taheri MS, Parsafar H: A case of central retinal artery occlusion following embolization procedure for juvenile nasopharyngeal angiofibroma. Indian J Ophthalmol; 2010 Sep-Oct;58(5):419-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of central retinal artery occlusion following embolization procedure for juvenile nasopharyngeal angiofibroma.
  • A 23-year-old male patient with right nasal Juvenile Nasopharyngeal Angiofibroma (JNA) developed Central Retinal Artery Occlusion (CRAO) during embolization of the tumor using polyvinyl alcohol particles before endoscopic excision.
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic / adverse effects. Nasopharyngeal Neoplasms / therapy. Retinal Artery Occlusion / etiology

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  • (PMID = 20689199.001).
  • [ISSN] 1998-3689
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2992919
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18. Korol UB, Schoor R, Nanda V, Almas K, Phelan JA: Gingival enlargement as a manifestation of tuberous sclerosis: case report and periodontal management. J Periodontol; 2008 Apr;79(4):759-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Tuberous sclerosis is an autosomal-dominant inherited disease involving many organs of the body.
  • Oral manifestations include gingival enlargement, fibromas, and dental enamel pitting.
  • The report presents a case of tuberous sclerosis with gingival enlargement histologically consistent with angiofibroma, describes its successful periodontal management, and reviews the literature associated with oral manifestations of tuberous sclerosis.
  • RESULTS: Histologic examination of the gingival tissue revealed features consistent with angiofibroma.
  • CONCLUSIONS: The gingival enlargement was histologically consistent with the characteristic angiofibromas of tuberous sclerosis.
  • [MeSH-minor] Adult. Angiofibroma / pathology. Debridement. Dental Scaling. Follow-Up Studies. Gingival Neoplasms / pathology. Gingivectomy. Humans. Male. Toothbrushing

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  • (PMID = 18380572.001).
  • [ISSN] 0022-3492
  • [Journal-full-title] Journal of periodontology
  • [ISO-abbreviation] J. Periodontol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
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19. Celenk P, Alkan A, Canger EM, Günhan O: Fibrolipomatous hamartoma in a patient with tuberous sclerosis: report of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Feb;99(2):202-6
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  • [Title] Fibrolipomatous hamartoma in a patient with tuberous sclerosis: report of a case.
  • Tuberous sclerosis is a rare congenital disorder with an incidence of 1 in 6000 births.
  • The classic triad is seizure, mental deficiency, and angiofibromas.
  • Orofacial manifestations include fibrous hyperplasia, hemangioma, bifid uvula, cleft lip and palate, macroglossia, high arched palate, and enamel defects.
  • Benign tumors of the jaws including desmoplastic fibroma, calcifying odontogenic tumor, and odontogenic myxoma have been recently reported in tuberous sclerosis.
  • [MeSH-major] Hamartoma / complications. Mandibular Diseases / complications. Tuberous Sclerosis / complications

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  • (PMID = 15660093.001).
  • [ISSN] 1079-2104
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-34-5 / Collagen
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20. Zhang QX, Ye J, Zhang SM, Li M: [Endoscopic nasal surgery in the treatment of nasopharyngeal angiofibroma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2005 Mar;40(3):222-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopic nasal surgery in the treatment of nasopharyngeal angiofibroma].
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 15952579.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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21. Hodges JM, McDevitt AS, El-Sayed Ali AI, Sebelik ME: Juvenile nasopharyngeal angiofibroma: current treatment modalities and future considerations. Indian J Otolaryngol Head Neck Surg; 2010 Sep;62(3):236-47
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  • [Title] Juvenile nasopharyngeal angiofibroma: current treatment modalities and future considerations.
  • Juvenile angiofibroma (JNA) is a relatively uncommon, highly vascular and benign tumor that presents most commonly in adolescent males.
  • With the advent of more sophisticated capabilities such as CT, MRI, intensity-modulated radiation therapy (IMRT), stereotactic guidance systems as well as advanced embolization techniques, these tumors can be diagnosed and managed more effectively.Patients with juvenile angiofibroma (JNA) are typically silent for years and often present with epistaxis, nasal obstruction, facial numbness, rhinorrhea, ear popping, sinusitis, cheek swelling, visual changes and headaches.
  • In addition to these symptoms, up to one-third of patients with this condition may present with proptosis or other orbital involvement, which are late symptoms and findings.Most physicians agree that surgery is the primary treatment modality for the early-stage disease process.
  • However, controversy arises regarding the best treatment when a patient presents with more locally advanced disease involving widespread cranial-based extension or intracranial involvement which may necessitate a combination of treatment modalities including surgery and postoperative radiation.With the advancement of endoscopic surgery, there have been a number of cases reporting the value of its use.

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  • (PMID = 23120720.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450247
  • [Keywords] NOTNLM ; Angiofibroma / Cyberknife / Embolization / Endoscopic surgery / IMRT / Image guided robotic radiotherapy / Skull base / Vascular tumor
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22. Mohindra S, Grover G, Bal AK: Extranasopharyngeal angiofibroma of the nasal septum: a case report. Ear Nose Throat J; 2009 Nov;88(11):E17-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extranasopharyngeal angiofibroma of the nasal septum: a case report.
  • Angiofibroma arising outside the nasopharynx is unusual.
  • The nasal septum is an extremely rare site for the origin of angiofibroma, and to date only 6 such cases previously have been reported in the literature.
  • We report here a case of a 22-year-old man with a vascular mass arising from his nasal septum.
  • The histopathology report was consistent with angiofibroma.
  • We also review other cases in the literature of angiofibroma arising from the nasal septum and discuss a theory of the likely origin of angiofibroma.
  • [MeSH-major] Angiofibroma / diagnosis. Nasal Septum / pathology. Nasopharyngeal Neoplasms / diagnosis. Nose Neoplasms / diagnosis

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  • (PMID = 19924651.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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23. Schick B, Veldung B, Wemmert S, Jung V, Montenarh M, Meese E, Urbschat S: p53 and Her-2/neu in juvenile angiofibromas. Oncol Rep; 2005 Mar;13(3):453-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p53 and Her-2/neu in juvenile angiofibromas.
  • The pathogenesis of juvenile angiofibroma (JA) remains unsolved.
  • [MeSH-major] Angiofibroma / genetics. Angiofibroma / physiopathology. Chromosomes, Human, Pair 17. Gene Expression Profiling. Receptor, ErbB-2 / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis

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  • (PMID = 15706416.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / Tumor Suppressor Protein p53; EC 2.7.10.1 / Receptor, ErbB-2
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24. Gengler C, Guillou L: Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology; 2006 Jan;48(1):63-74
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  • [Title] Solitary fibrous tumour and haemangiopericytoma: evolution of a concept.
  • Over the years, it appeared that this growth pattern was a non-specific one, shared by numerous, unrelated benign and malignant lesions, and that HPC was better considered as a diagnosis of exclusion.
  • They generally show a benign clinical course, and include glomangiopericytoma/myopericytoma, infantile myofibromatosis (previously called infantile HPC), and a subset of sinonasal HPCs.
  • The third category is the solitary fibrous tumour (SFT) lesional group, which includes fibrous-to-cellular SFTs, and related lesions such as giant cell angiofibromas and lipomatous HPCs.
  • [MeSH-major] Fibroma / diagnosis. Hemangiopericytoma / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 16359538.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 70
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25. Satish Chandra A, Mohanty S: Subselective embolisation in management of JNA. Indian J Otolaryngol Head Neck Surg; 2007 Mar;59(1):43-4
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  • Role of Embolisation in preoperative management of Nasopharyngeal angiofibroma is well established in present day therapeutic modalities.

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  • [Cites] Radiology. 1979 Sep;132(3):631-9 [472240.001]
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  • (PMID = 23120383.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3451726
  • [Keywords] NOTNLM ; Digital Subtraction Angiography (DSE) / Juvenile Nasopharyngeal Angiofibroma / Subselective Embolisation (SSE)
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26. McNiff JM, Subtil A, Cowper SE, Lazova R, Glusac EJ: Cellular digital fibromas: distinctive CD34-positive lesions that may mimic dermatofibrosarcoma protuberans. J Cutan Pathol; 2005 Jul;32(6):413-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cellular digital fibromas: distinctive CD34-positive lesions that may mimic dermatofibrosarcoma protuberans.
  • BACKGROUND: Digital fibromas are common benign acral tumors typically reported as angiofibromas (AFs) or acquired digital fibrokeratomas (ADFs).
  • We compared the histologic and immunohistochemical features of these cellular fibromas with five digital AFs, five ADFs, and five digital dermatofibromas.
  • RESULTS: The 14 cellular digital fibromas showed intersecting fascicles of thin delicate bland spindle cells in the superficial reticular dermis with a fibrotic-to-slight myxoid stroma.
  • CONCLUSIONS: These findings suggest that a subset of digital fibromas is characterized by a dense cellular proliferation of CD34-positive spindle cells.
  • Awareness of this variant of digital fibroma and its staining pattern is critical in preventing misdiagnosis as dermatofibrosarcoma protuberans, particularly in superficial biopsies.
  • [MeSH-major] Dermatofibrosarcoma / pathology. Fibroma / pathology. Fingers / pathology. Neoplasms, Connective Tissue / pathology. Skin Neoplasms / pathology


27. Heinrich UR, Brieger J, Gosepath J, Wierzbicka M, Sokolov M, Roth Y, Szyfter W, Bittinger F, Mann WJ: Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma. Cancer Genet Cytogenet; 2007 Jun;175(2):138-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor, mostly affecting adolescent males.
  • No DNA aneuploidy was detected, a finding in accordance with the generally benign characteristics of JNAs.
  • Autosomal gains in the primary tumor should be further evaluated as markers for a potentially increased risk of recurrence after surgical removal in this entity.
  • [MeSH-major] Angiofibroma / genetics. Chromosome Aberrations. Nasopharyngeal Neoplasms / genetics. Neoplasm Recurrence, Local / genetics

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  • (PMID = 17556070.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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28. Renukananda GS, Basavaraja PK, Naik AS, Maheshwari M, Balaji NK, Thangavelu G: Atypical angiofibroma of larynx - a case report. Indian J Otolaryngol Head Neck Surg; 2008 Mar;60(1):51-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical angiofibroma of larynx - a case report.
  • Primary extra nasopharyngeal angiofibroma of larynx is a very rare tumour.
  • We here by present a case of angiofibroma of larynx affecting the anterior commissure & subglottic region in larynx-a rare site of involvement.

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  • (PMID = 23120500.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450725
  • [Keywords] NOTNLM ; Atypical angiofibroma / Extranasopharyngeal angiofibroma / Histolo gy
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29. Giavroglou C, Constantinidis J, Triaridis S, Daniilidis J, Dimitriadis A: [Angiographic evaluation and embolization of juvenile nasopharyngeal angiofibroma]. HNO; 2007 Jan;55(1):36-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiographic evaluation and embolization of juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Juveniles Angiofibrom: Angiographische Diagnostik und präoperative Embolisation.
  • OBJECTIVE: In juvenile nasopharyngeal angiofibroma (JNA), analysis of tumor extension and blood supply is useful for controlling intraoperative bleeding and helps in determining the appropriate surgical approach.
  • [MeSH-major] Angiofibroma / diagnostic imaging. Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / diagnostic imaging. Nasopharyngeal Neoplasms / therapy. Neoplasm Recurrence, Local / prevention & control

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  • (PMID = 16775738.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
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30. Uyar M, Turanli M, Pak I, Bakir S, Osma U: Extranasopharyngeal angiofibroma originating from the nasal septum: a case report. Kulak Burun Bogaz Ihtis Derg; 2009 Jan-Feb;19(1):41-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extranasopharyngeal angiofibroma originating from the nasal septum: a case report.
  • Angiofibromas (AFs) originate predominantly in the nasopharynx and posterior nasal cavity.
  • Only four cases of extranasopharyngeal angiofibromas arising in the nasal septum have been reported so far.
  • We report here a case of a vascular mass arising from the nasal septum in a 19-year-old boy which was extirpated by submucousal resection endonasally.
  • Histopathology confirmed it to be a case of angiofibroma.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Nasal Septum. Nose Neoplasms / diagnosis. Nose Neoplasms / surgery

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  • (PMID = 19793047.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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31. Nicolai P, Villaret AB, Farina D, Nadeau S, Yakirevitch A, Berlucchi M, Galtelli C: Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases. Am J Rhinol Allergy; 2010 Mar-Apr;24(2):e67-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases.
  • BACKGROUND: At present, transnasal endoscopic surgery is considered a viable option in the management of small-intermediate size juvenile angiofibromas (JAs).
  • The lesions were classified according to Andrews (Andrews JC, et al., The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach, Laryngoscope 99:429-437, 1989) and Onerci (Onerci M, et al.
  • Juvenile nasopharyngeal angiofibroma: A revised staging system, Rhinology 44:39-45, 2006) staging systems.
  • RESULTS: Lesions were classified as follows: stage I, n = 5; stage II, n = 24; stage IIIa, n = 14; stage IIIb, n = 3 according to Andrews classification system; stage 1, n = 9; stage II, n = 12; stage III, n = 26 according to Onerci's system.
  • In four (8.7%) cases, suspicious residual disease was detected by MRI.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nose Neoplasms / surgery

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  • (PMID = 20338105.001).
  • [ISSN] 1945-8932
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. McCluggage WG: A review and update of morphologically bland vulvovaginal mesenchymal lesions. Int J Gynecol Pathol; 2005 Jan;24(1):26-38
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  • Vulvovaginal mesenchymal lesions composed of morphologically bland spindle-shaped cells often pose a particular diagnostic problem for the surgical pathologist not only because of the rarity of these lesions but also because of the wide array of entities with overlapping morphologic features.
  • Lesions that are relatively specific to the vulvovaginal region include well-known neoplasms such as aggressive angiomyxoma and angiomyofibroblastoma as well as more recently described lesions such as cellular angiofibroma and superficial cervicovaginal myofibroblastoma.
  • [MeSH-minor] Angiofibroma / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Mesoderm. Myxoma / pathology. Neoplasms, Muscle Tissue / pathology. Polyps / pathology

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  • (PMID = 15626915.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 81
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33. Perez EG, Paranaíba LR, Bonan PR, Orsi Júnior JM, Oliveira AM, Martelli Júnior H: [Tuberous sclerosis: evaluation of myofibroblasts in cutaneous angiofibromas - case report]. An Bras Dermatol; 2010 Jan-Feb;85(1):84-8
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  • [Title] [Tuberous sclerosis: evaluation of myofibroblasts in cutaneous angiofibromas - case report].
  • [Transliterated title] Esclerose tuberosa: avaliação de miofibroblastos em angiofibromas cutâneos - relato de caso.
  • Tuberous sclerosis is a rare autosomal dominant disorder.
  • The objective of this study is to describe clinical and histopathological characteristics of tuberous sclerosis and to conduct an immunohistochemical evaluation of myofibroblasts in cutaneous angiofibromas present in this condition.
  • Since alpha-SMA is a specific marker for myofibroblasts, this result suggests that myofibroblasts are not involved in cutaneous angiofibromas present in the tuberous sclerosis case reported.
  • [MeSH-major] Angiofibroma / complications. Angiofibroma / pathology. Fibroblasts / pathology. Skin Neoplasms / complications. Skin Neoplasms / pathology. Tuberous Sclerosis / complications


34. Ardehali MM, Samimi Ardestani SH, Yazdani N, Goodarzi H, Bastaninejad S: Endoscopic approach for excision of juvenile nasopharyngeal angiofibroma: complications and outcomes. Am J Otolaryngol; 2010 Sep-Oct;31(5):343-9
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  • [Title] Endoscopic approach for excision of juvenile nasopharyngeal angiofibroma: complications and outcomes.
  • The purposes of this study are to report the efficacy of the endoscopic approach for juvenile nasopharyngeal angiofibroma (JNA) and to compare its related intra- and postoperative complications with findings from traditional approaches in the literatures.
  • [MeSH-major] Angiofibroma / therapy. Endoscopy. Nasopharyngeal Neoplasms / therapy

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20015778.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Zhou SH, Wang SQ, Wang QY: [Atypical angiofibroma in inferior nasal turbinate: report of a case]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Jan;43(1):68
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  • [Title] [Atypical angiofibroma in inferior nasal turbinate: report of a case].
  • [MeSH-major] Angiofibroma. Nose Diseases. Turbinates / pathology

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  • (PMID = 18357720.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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37. McCluggage WG: Recent developments in vulvovaginal pathology. Histopathology; 2009 Jan;54(2):156-73
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  • HMGA2 is useful in the diagnosis of aggressive angiomyxoma and its distinction from mimics, in the evaluation of resection margins and in the assessment of the presence or absence of residual disease in re-excisions.
  • Aggressive angiomyxoma is almost invariably positive with oestrogen and progesterone receptors, and there have been several reports of a dramatic reduction in size following gonadotropin releasing hormone agonist therapy.
  • Recent series of the relatively newly described entities cellular angiofibroma and superficial myofibroblastoma of the lower female genital tract have expanded upon the morphological spectrum of these neoplasms.
  • Recently described mesenchymal lesions at this site include massive oedema and prepubertal vulval fibroma.
  • Gastrointestinal stromal tumours have been described as primary neoplasms in the vagina, and rectovaginal septum and extragastrointestinal stromal tumour should be added to the differential diagnosis of a vulvovaginal mesenchymal lesion.
  • There have been new developments regarding Paget's disease of the vulva with the identification of markers that are useful in diagnosis and evidence that the neoplastic cells represent a proliferation of adnexal stem cells residing in sebaceous units.
  • [MeSH-major] Vaginal Diseases / pathology. Vulvar Diseases / pathology

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  • (PMID = 18637148.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 138
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38. Padilla Parrado M, Díaz Sastre MA, Jiménez Antolín JA, Caro García MA: [Juvenile nasopharyngeal angiofibroma]. An Otorrinolaringol Ibero Am; 2005;32(4):361-71
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  • [Title] [Juvenile nasopharyngeal angiofibroma].
  • [Transliterated title] Angiofibroma nasofaringeo juvenil. Situación actual.
  • Juvenile Juvenile nasopharyngeal angiofibroma (JNA) is a benign and highly vascular tumor.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 16156366.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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39. Piperi E, Rohrer MD, Pambuccian SE, Koutlas IG: Vascular solitary fibrous tumor with "floret" cells or giant cell angiofibroma? A lingual example highlighting the overlapping characteristics of these entities and positive immunoreaction for estrogen and progesterone receptors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 May;107(5):685-90
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  • [Title] Vascular solitary fibrous tumor with "floret" cells or giant cell angiofibroma? A lingual example highlighting the overlapping characteristics of these entities and positive immunoreaction for estrogen and progesterone receptors.
  • Recent literature suggests that giant cell angiofibroma (GCAF) is a variant of solitary fibrous tumor (SFT) and not just a related lesion.
  • We support the present notion that GCAF is a histologic subtype of SFT.
  • [MeSH-major] Angiofibroma / pathology. Solitary Fibrous Tumors / pathology. Tongue Neoplasms / pathology. Vascular Neoplasms / pathology

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  • (PMID = 19272802.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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40. Sun Y, Wu Z: [Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Dec;20(23):1076-8
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  • [Title] [Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma].
  • OBJECTIVE: To investigate the nature of juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma / metabolism. Endothelial Cells / metabolism. Fibroblast Growth Factors / metabolism. Nasopharyngeal Neoplasms / metabolism. Proliferating Cell Nuclear Antigen / metabolism. Vascular Endothelial Growth Factor A / metabolism

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  • (PMID = 17285972.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 0 / fibroblast growth factor 13; 62031-54-3 / Fibroblast Growth Factors
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41. Carlos R, Thompson LD, Netto AC, Pimenta LG, Correia-Silva Jde F, Gomes CC, Gomez RS: Epstein-Barr virus and human herpes virus-8 are not associated with juvenile nasopharyngeal angiofibroma. Head Neck Pathol; 2008 Sep;2(3):145-9
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  • [Title] Epstein-Barr virus and human herpes virus-8 are not associated with juvenile nasopharyngeal angiofibroma.
  • BACKGROUND: Nasopharyngeal angiofibroma (also known as juvenile nasopharyngeal angiofibroma) is a rare fibroblastic tumor with a vascular component that occurs in the nasopharynx and posterolateral nasal wall of adolescent boys.
  • The etiology of nasopharyngeal angiofibroma remains elusive.
  • MATERIALS AND METHODS: Formalin fixed, routinely processed, and paraffin embedded surgical specimens of 15 angiofibromas were submitted to PCR for EBV and HHV-8, while in situ hybridization was also employed for EBV.
  • CONCLUSION: Angiofibroma does not appear to be associated with either HHV-8 or EBV, thereby excluding these viruses as potential etiologic agents.
  • The lack of a correlation between the proliferative index and the age of the patient suggests the proposed puberty induced, testosterone-dependent tumor growth may not play a significant role in tumor development.
  • [MeSH-major] Angiofibroma / virology. Epstein-Barr Virus Infections / virology. Herpesviridae Infections / virology. Herpesvirus 4, Human / isolation & purification. Herpesvirus 8, Human / isolation & purification. Nasopharyngeal Neoplasms / virology

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  • (PMID = 20614308.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Viral; 0 / EBV-associated membrane antigen, Epstein-Barr virus; 0 / Ki-67 Antigen; 0 / Viral Matrix Proteins
  • [Other-IDs] NLM/ PMC2807556
  • [Keywords] NOTNLM ; Adolescent / Angiofibroma / EBV / HHV-8 / Immunohistochemistry / In situ hybridization / Ki-67 / MIB / Males / Molecular / Nasopharyngeal juvenile angiofibroma / Neoplasm / Tumor growth / Vascular
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42. Zeller S, Marx SJ, Lungu AO, Cowen EW, Turner ML: Multiple angiofibromas and collagenomas in a 45-year-old man with recurrent nephrolithiasis, fatigue, and vision loss. J Am Acad Dermatol; 2009 Aug;61(2):319-22
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  • [Title] Multiple angiofibromas and collagenomas in a 45-year-old man with recurrent nephrolithiasis, fatigue, and vision loss.
  • [MeSH-major] Angiofibroma / diagnosis. Multiple Endocrine Neoplasia Type 1 / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adrenalectomy / methods. Biopsy, Needle. Collagen Diseases / complications. Collagen Diseases / diagnosis. Fatigue / complications. Fatigue / diagnosis. Follow-Up Studies. Humans. Immunohistochemistry. Male. Middle Aged. Nephrolithiasis / complications. Nephrolithiasis / diagnosis. Pancreatectomy. Recurrence. Risk Assessment. Severity of Illness Index. Splenectomy / methods. Vision Disorders / complications. Vision Disorders / diagnosis

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  • (PMID = 19615541.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z99 CA999999
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS135687; NLM/ PMC2744374
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43. Horowitz G, Gil Z, Kavel O, Smith D, Sela M, Abargel A, Fliss D: [Surgical treatment of maxillary tumors]. Harefuah; 2010 Nov;149(11):704-7, 749
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  • METHODS: A total of 174 patients underwent surgery due to neoplasms originating in the maxillary sinus: 118 patients (68%) had malignant and 54 (32%) had benign tumors.
  • RESULTS: The most common malignancy was squamous cell carcinoma (40%), and the most common benign tumor was juvenile nasopharyngeal angiofibroma (36%).
  • Among patients with malignant tumors, 75 are alive without disease (67%), 12 (10%) are alive with disease and 31 (23%) died of disease or other causes.
  • [MeSH-minor] Angiofibroma / mortality. Angiofibroma / surgery. Carcinoma, Squamous Cell / mortality. Carcinoma, Squamous Cell / surgery. Humans. Maxilla / surgery. Melanoma / mortality. Melanoma / surgery. Nasopharyngeal Neoplasms / mortality. Nasopharyngeal Neoplasms / surgery. Retrospective Studies. Sarcoma / mortality. Sarcoma / surgery. Survival Rate

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  • (PMID = 21250410.001).
  • [ISSN] 0017-7768
  • [Journal-full-title] Harefuah
  • [ISO-abbreviation] Harefuah
  • [Language] heb
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Israel
  • [Chemical-registry-number] Nasopharyngeal carcinoma
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44. Martelli H, Lima LS, Bonan PR, Coletta RD: Oral manifestations leading to the diagnosis of familial tuberous sclerosis. Indian J Dent Res; 2010 Jan-Mar;21(1):138-40
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  • We reported herein a nine-year-old boy with dental enamel pits and gingival nodular lesions, histologically diagnosed as angiofibromas that leaded to the diagnosis of a family with TS.
  • [MeSH-major] Angiofibroma / etiology. Dental Enamel Hypoplasia / etiology. Facial Neoplasms / etiology. Gingival Neoplasms / etiology. Tuberous Sclerosis / diagnosis

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  • (PMID = 20427926.001).
  • [ISSN] 1998-3603
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] India
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45. Danesi G, Panciera DT, Harvey RJ, Agostinis C: Juvenile nasopharyngeal angiofibroma: evaluation and surgical management of advanced disease. Otolaryngol Head Neck Surg; 2008 May;138(5):581-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: evaluation and surgical management of advanced disease.
  • Describe the outcomes in surgically treated juvenile nasopharyngeal angiofibroma (JNA) with the influence of middle cranial fossa, carotid, or dural involvement on recurrence.
  • RESULTS: Recurrence for advanced disease (IIIb+) was 18.2% (6 of 33) and 15.3% (13 of 85) overall.
  • CONCLUSION: Dural involvement by tumor is rare and imaging may overstage disease.
  • When an open approach is used, a midface degloving technique affords excellent exposure even for advanced disease.
  • Lateral approaches with their associated morbidity can be reserved for selected recurrent disease.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Nasopharyngeal Neoplasms / diagnosis. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18439462.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Margalit N, Wasserzug O, De-Row A, Abergel A, Fliss DM, Gil Z: Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article. J Neurosurg Pediatr; 2009 Aug;4(2):113-7
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  • [Title] Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article.
  • OBJECT: The purpose of this study was to describe the surgical treatment and outcomes of patients with intracranial extension of juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / surgery. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / surgery

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  • [CommentIn] J Neurosurg Pediatr. 2012 Mar;9(3):336-7; author reply 337 [22380966.001]
  • (PMID = 19645542.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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47. Val-Bernal JF, Rubio S, Garijo MF, González-Vela MC: Extragenital subcutaneous cellular angiofibroma. Case report. APMIS; 2007 Mar;115(3):254-8
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  • [Title] Extragenital subcutaneous cellular angiofibroma. Case report.
  • Cellular angiofibroma (CAF) is a rare distinctive mesenchymal neoplasm that occurs almost exclusively in the genital area.
  • We report the case of a 38-year-old woman who presented with an asymptomatic subcutaneous mass, 3.5 cm in diameter, located in the left hypochondrium, which had progressively enlarged during the previous 6 months.
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / surgery. Skin Neoplasms / pathology

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  • (PMID = 17367472.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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48. Eze NN, Wyatt ME, Bray D, Bailey CM, Hartley BE: The midfacial degloving approach to sinonasal tumours in children. Rhinology; 2006 Mar;44(1):36-8
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  • The procedure allows access to benign and malignant lesions of the sinonasal region with the avoidance of an external scar.
  • Eight children had benign pathology.
  • There were two juvenile angiofibromas, two nasal gliomas, one ossifying fibroma, one fibroma, one fibrous dysplasia and one benign myofibroblastic proliferation.
  • One child had malignant disease in the form of recurrent embryonal rhabdomyosarcoma.

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  • (PMID = 16550948.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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49. Krstulja M, Kujundzić M, Halaj A, Braut T, Cvjetković N: Radiofrequency-induced thermotherapy of nasopharyngeal angiofibroma and immunohistochemical analysis of vessel proliferation: a case report. J Med Case Rep; 2008;2:278
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  • [Title] Radiofrequency-induced thermotherapy of nasopharyngeal angiofibroma and immunohistochemical analysis of vessel proliferation: a case report.
  • INTRODUCTION: Nasopharyngeal angiofibroma presents with symptoms of nasal obstruction and epistaxis.
  • CASE PRESENTATION: A 52-year-old man underwent surgery for nasopharyngeal angiofibroma after adjuvant radiofrequency-induced thermotherapy.
  • To the best of the authors' knowledge, this is the first case of angiofibroma with clinical follow-up after thermocoagulation therapy supported by quantitative, double immunohistochemistry.
  • We found this case of angiofibroma to be of interest owing to the presentation of symptoms leading to biopsy, the pathohistological observations obtained with synchronous Ki67/cluster of differentiation 34 and Ki67/smooth muscle actin immunohistochemistry and high pericyte proliferation.
  • CONCLUSION: Coagulation of angiofibroma vessels followed by acquisition of a thick mantle of pericytes in a patient with a nasopharyngeal growth suggests that radiofrequency-induced thermotherapy could be a useful, palliative therapy for bleeding nasopharyngeal angiofibroma, supporting vessel maturation prior to surgical tumor removal.

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  • (PMID = 18706100.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2535598
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50. Chen E, Fletcher CD: Cellular angiofibroma with atypia or sarcomatous transformation: clinicopathologic analysis of 13 cases. Am J Surg Pathol; 2010 May;34(5):707-14
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  • [Title] Cellular angiofibroma with atypia or sarcomatous transformation: clinicopathologic analysis of 13 cases.
  • Cellular angiofibroma is a mesenchymal neoplasm that is characterized by a bland spindle cell component, morphologically reminiscent of spindle cell lipoma, and thick-walled vessels.
  • An earlier study of 51 cases from our group showed that the tumor follows a benign course without any tendency for recurrence.
  • The biologic significance of atypia or sarcomatous transformation in cellular angiofibroma remains uncertain.
  • In this study, we characterized clinicopathologic features in 13 cases of cellular angiofibroma with morphologic atypia or sarcomatous transformation.
  • Thirteen cases with atypia or sarcomatous transformation among 154 usual cellular angiofibromas identified between 1993 and 2009 were retrieved from consultation files.
  • There were 4 cases of cellular angiofibroma with atypia.
  • Three showed severely atypical cells as scattered foci within the cellular angiofibroma.
  • There were 9 cases of cellular angiofibroma with morphologic features of sarcomatous transformation.
  • Three of these 9 cases showed discrete nodule(s) closely resembling atypical lipomatous tumor within usual cellular angiofibroma.
  • By immunohistochemistry, atypical cells and sarcomatous areas showed either multifocal or more diffuse p16 expression compared with either scattered or negative expression in the conventional cellular angiofibroma.
  • One patient died of metastatic carcinoma of unknown primary site 27 months after the diagnosis of cellular angiofibroma with sarcomatous transformation.
  • Cellular angiofibroma with atypia or morphologic sarcomatous transformation occurs predominantly in the subcutaneous tissue of the vulva and, as yet, shows no evident tendency to recur based on limited clinical follow-up available for 7 cases.
  • The sarcomatous component can show variable features including atypical lipomatous tumor, pleomorphic liposarcoma, and pleomorphic sarcoma NOS.
  • [MeSH-major] Angiofibroma / pathology. Cell Transformation, Neoplastic. Sarcoma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 20305534.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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51. Shcherbenko OI, Rodionov MV, Lebedev VA, Kliachkina NB: [Efficacy of remote gamma-therapy in patients with juvenile angiofibroma of the base of the skull]. Vestn Otorinolaringol; 2008;(3):26-8
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  • [Title] [Efficacy of remote gamma-therapy in patients with juvenile angiofibroma of the base of the skull].
  • The results of radiation therapy of 48 patients with juvenile nasopharyngeal angiofibroma were analysed.
  • [MeSH-major] Angiofibroma / radiotherapy. Gamma Rays / therapeutic use. Skull Base Neoplasms / radiotherapy

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  • (PMID = 18833092.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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52. Satgé D, Vidalo E, Desfarges F, de Geeter B: A third case of cardiac neoplasm in a fetus with Beckwith-Wiedemann syndrome: epicardial angiofibroma. Fetal Diagn Ther; 2005 Jan-Feb;20(1):44-7
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  • [Title] A third case of cardiac neoplasm in a fetus with Beckwith-Wiedemann syndrome: epicardial angiofibroma.
  • OBJECTIVE: A personal observation of a 20-week-old fetus with Beckwith-Wiedemann syndrome (BWS) presenting epicardial angiofibroma prompted us to evaluate cardiac neoplasms in this genetic condition.
  • [MeSH-major] Angiofibroma / etiology. Beckwith-Wiedemann Syndrome / complications. Fetal Diseases. Heart Neoplasms / etiology. Pericardium
  • [MeSH-minor] Adult. Female. Hamartoma / etiology. Hamartoma / pathology. Heart Diseases / etiology. Heart Diseases / pathology. Humans. Pregnancy. Pregnancy Trimester, First

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  • (PMID = 15608459.001).
  • [ISSN] 1015-3837
  • [Journal-full-title] Fetal diagnosis and therapy
  • [ISO-abbreviation] Fetal. Diagn. Ther.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 15
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53. Spielmann PM, Adamson R, Cheng K, Sanderson RJ: Juvenile nasopharyngeal angiofibroma: spontaneous resolution. Ear Nose Throat J; 2008 Sep;87(9):521-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile nasopharyngeal angiofibroma: spontaneous resolution.
  • Juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males.
  • We report the case of a 17-year-old male who presented in 1995 with a mass filling the left posterior nasal cavity.
  • A diagnosis of juvenile nasopharyngeal angiofibroma was obtained with computed tomography and magnetic resonance imaging.
  • [MeSH-major] Angiofibroma / diagnosis. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 18800325.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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54. Nomura K, Shimomura A, Awataguchi T, Murakami K, Kobayashi T: A case of angiofibroma originating from the inferior nasal turbinate. Auris Nasus Larynx; 2006 Jun;33(2):191-3
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  • [Title] A case of angiofibroma originating from the inferior nasal turbinate.
  • Angiofibromas are nasopharyngeal tumors mostly seen in adolescent males.
  • Extranasopharyngeal angiofibromas, although rare, have been reported.
  • We report a case of extranasopharyngeal angiofibroma arising from the inferior turbinate of a 62-year-old male.
  • Previous extranasopharyngeal angiofibromas research was reviewed.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology. Turbinates / pathology

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  • (PMID = 16310998.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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55. Joo D, Chhetri DK, Wang MB: Endoscopic removal of juvenile nasopharyngeal angiofibromas: a video presentation. Laryngoscope; 2008 Jun;118(6):e1-3
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  • [Title] Endoscopic removal of juvenile nasopharyngeal angiofibromas: a video presentation.
  • OBJECTIVES/HYPOTHESIS: Juvenile nasal angiogibroma (JNA) is a relatively rare, benign neoplasm generally seen in prepubertal and adolescent males.
  • Through the use of a brief video presentation, participants will be able to visualize the endoscopic technique.
  • RESULTS: A video demonstration is presented of a patient with a 3.5 cm JNA who underwent successful endoscopic, endonasal excision.
  • The tumor was resected en bloc with minimal bleeding.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasal Cavity. Nasopharyngeal Neoplasms / surgery. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 18391769.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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56. de Vries PJ, Hunt A, Bolton PF: The psychopathologies of children and adolescents with tuberous sclerosis complex (TSC): a postal survey of UK families. Eur Child Adolesc Psychiatry; 2007 Feb;16(1):16-24
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  • Tuberous Sclerosis Complex (TSC) is a multi-system genetic disorder associated with a wide range of physical features and very high rates of numerous neurocognitive manifestations.
  • Children with MR were significantly more likely to have an autism spectrum disorder, attention deficit-related symptoms and speech and language difficulties.
  • They were more likely to have a history of epilepsy, facial angiofibromata and shagreen patches and tended to have a greater number of physical features of the disorder.
  • However, about one third of the children without MR had features suggestive of a developmental disorder.
  • These findings show that TSC can place any child or adolescent at significantly increased risk of a range of neurodevelopmental disabilities.

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  • (PMID = 17268883.001).
  • [ISSN] 1018-8827
  • [Journal-full-title] European child & adolescent psychiatry
  • [ISO-abbreviation] Eur Child Adolesc Psychiatry
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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57. Janaki MG, Nirmala S, Rajeev AG: Nasopharyngeal angiofibroma treated with radiotherapy. J Cancer Res Ther; 2007 Apr-Jun;3(2):100-1
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  • [Title] Nasopharyngeal angiofibroma treated with radiotherapy.
  • Nasopharyngeal angiofibroma is a rare, highly vascular, benign, locally aggressive tumor, affecting boys of adolescent age.
  • Although surgery is the treatment of choice in early cases, considerable debate exists regarding the treatment of advanced disease with intracranial extension.
  • We are herewith reporting a case of nasopharyngeal angiofibroma who showed complete hemostasis and improvement in vision to radiotherapy.
  • [MeSH-major] Angiofibroma / radiotherapy. Nasopharyngeal Neoplasms / radiotherapy

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  • (PMID = 17998732.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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58. Snyderman CH, Pant H, Carrau RL, Gardner P: A new endoscopic staging system for angiofibromas. Arch Otolaryngol Head Neck Surg; 2010 Jun;136(6):588-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A new endoscopic staging system for angiofibromas.
  • OBJECTIVE: To develop a new staging system for juvenile nasopharyngeal angiofibroma that reflects changes in surgical approaches (endonasal), route of intracranial extension, and the extent of vascular supply from the internal carotid artery.
  • PATIENTS: Patients undergoing endoscopic endonasal surgery for juvenile nasopharyngeal angiofibroma at the University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, from 1998 through 2008.
  • CONCLUSIONS: Tumor size and extent of sinus disease are less important in predicting complete tumor removal with endonasal surgical techniques.
  • The UPMC staging system for juvenile nasopharyngeal angiofibroma accounts for 2 important prognostic factors, route of cranial base extension, and vascularity and is applicable to endoscopic or open approaches.
  • [MeSH-major] Angiofibroma / pathology. Endoscopy. Nasopharyngeal Neoplasms / pathology. Neoplasm Staging / standards


59. Parikh SR, Cuellar H, Sadoughi B, Aroniadis O, Fried MP: Indications for image-guidance in pediatric sinonasal surgery. Int J Pediatr Otorhinolaryngol; 2009 Mar;73(3):351-6
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  • Indications for surgery included chronic (30.3%) and acute (12.1%) rhinosinusitis, nasopharyngeal angiofibroma (9.1%), allergic rhinosinusitis (9.1%) and allergic fungal sinusitis (9.1%).
  • In our population, image-guidance was only used for advanced sinonasal procedures where there was an anatomic abnormality or disease that extended to the sphenoid sinus, frontal sinus, orbit, or skull base.

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  • (PMID = 19157578.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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60. Surace D, Blandamura S, Bernardini FP, Galan A, Lo Giudice G: Unusual presentation of giant cell angiofibroma of the eyelids. Eur J Ophthalmol; 2010 Nov-Dec;20(6):1073-5
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  • [Title] Unusual presentation of giant cell angiofibroma of the eyelids.
  • PURPOSE: To describe a case of bilateral eyelid-confined giant cell angiofibroma (GCAF) in a patient with a slowly progressive bilateral eyelid swelling.
  • CONCLUSIONS: Giant cell angiofibroma involving the eyelid is rare and can represent a diagnostic and therapeutic challenge to the ophthalmologist.
  • [MeSH-major] Angiofibroma / diagnosis. Eyelid Neoplasms / diagnosis. Giant Cell Tumors / diagnosis

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  • (PMID = 20623470.001).
  • [ISSN] 1724-6016
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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61. Igaz P: MEN1 clinical background. Adv Exp Med Biol; 2009;668:1-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Beside these three, several other endocrine (adrenocortical, foregut carcinoid) and nonendocrine (lipoma, angiofibroma, collagenoma, ependymoma, meningioma) tumors have been described to be associated with this syndrome.
  • Both familial and sporadic forms of the disease are known.
  • Both benign (parathyroid, anterior pituitary) and malignant (gastrinoma, glucagonoma) lesions may develop in MEN1 patients.
  • Regular surveillance of MEN1 gene mutation carriers is necessary to reveal disease manifestations.
  • [MeSH-minor] Adult. Child. Child, Preschool. Diagnosis, Differential. Genetic Predisposition to Disease. Genetic Testing. Humans. Middle Aged. Multiple Endocrine Neoplasia Type 2a / genetics. Multiple Endocrine Neoplasia Type 2a / pathology. Multiple Endocrine Neoplasia Type 2a / physiopathology. Mutation. Young Adult

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  • (PMID = 20175448.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Timotin L, Sarrot-Reynauld F, Lantuejoul S, Pasquier B, Massot C, Ashraf A, Borgel F: [Tuberous sclerosis without mental impairment, diagnosed in adulthood]. Rev Med Interne; 2005 Jun;26(6):511-3
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  • [Transliterated title] Sclérose tubéreuse de Bourneville sans altération intellectuelle, diagnostiquée à l'âge adulte.
  • EXEGESIS: We report a case of TSC diagnosed in a 33-year-old man, without any known family history of phakomatosis, presenting with facial angiofibromas, hypomelanotic macules, a giant-cell astrocytoma and retinal phakomas without any mental impairment or epilepsy.
  • CONCLUSION: TSC may occur in patients who do not have any family history of phakomatosis because de novo mutations are frequent.
  • Facial angiofibromas are highly suggestive of tuberous sclerosis complex.

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  • (PMID = 15936480.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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63. Sen C, Alvarez G, Dagotto E: Competing ferromagnetic and charge-ordered states in models for manganites: the origin of the colossal magnetoresistance effect. Phys Rev Lett; 2007 Mar 23;98(12):127202
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  • The one-orbital model for manganites with cooperative phonons and superexchange coupling JAF is investigated via large-scale Monte Carlo simulations.

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  • (PMID = 17501153.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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64. Belcadhi M, Mani R, Harzallah M, Bouaouina N, Bouzouita K: [Nasopharyngeal angiofibroma with intracranial extension: situating the chemotherapy-radiotherapy association]. Cancer Radiother; 2008 Sep;12(5):385-8
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  • [Title] [Nasopharyngeal angiofibroma with intracranial extension: situating the chemotherapy-radiotherapy association].
  • [Transliterated title] L'angiofibrome nasopharyngien avec extension intracrânienne : place de l'association chimiothérapie-radiothérapie.
  • Nasopharyngeal angiofibroma is a locally aggressive, although histologically benign, vascular neoplasm.
  • Surgery is considered as the primary treatment of nasopharyngeal angiofibroma.
  • We report a rare case of nasopharyngeal angiofibroma, further complicated with a Kennedy syndrome in a 34 year-old women.
  • We discuss the relevance and outcome of the association chemotherapy-radiotherapy in the treatment of nasopharyngeal angiofibromas with a consistent intracranial extension (stage III B of Arch Otolaryngol Head Neck Surg 122 (2003) 122-129).
  • [MeSH-major] Angiofibroma / drug therapy. Angiofibroma / radiotherapy. Brain Neoplasms / radiotherapy. Nasopharyngeal Neoplasms / drug therapy. Nasopharyngeal Neoplasms / radiotherapy

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  • (PMID = 18339570.001).
  • [ISSN] 1278-3218
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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65. Zozulya YP, Slin'ko EI, Al-Qashqish II: Spinal arteriovenous malformations: new classification and surgical treatment. Neurosurg Focus; 2006;20(5):E7
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  • [Title] Spinal arteriovenous malformations: new classification and surgical treatment.
  • Insufficient study of this disease is connected with the complexity of its diagnosis, which restricts the development of surgical treatments that are differentiated according to the type of malformation.
  • Great difficulties are caused by the lack of a clear structural-hemodynamic classification of spinal arteriovenous malformations (AVMs).
  • At present the classification created between 1991 and 1998 by the combined efforts of different authors is the most widely used one.
  • According to this classification, four categories are distinguishable: Type I, dural arteriovenous fistulas (AVFs); Type II, intramedullary glomus AVMs; Type III, juvenile or combined AVMs; and Type IV, intradural perimedullary AVFs.
  • Vascular tumors are also classified, as follows: hemangiomas, hemangioblastomas, angiosarcomas, hemangiopericytomas, angiofibromas, angiolipomas, and hemangioendotheliomas, as well as cavernous malformations.
  • For spinal vascular malformations we devised a classification that took into account the aforementioned features of AVMs: the anatomical characteristics of a malformation and its angiostructural and hemodynamic features.
  • [MeSH-major] Arteriovenous Malformations / classification. Arteriovenous Malformations / surgery. Neurosurgical Procedures. Spinal Cord / blood supply

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  • (PMID = 16711664.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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66. Zhang QF, She CP, Tong YF, Jin Y, Zhang XR: [Endoscopic surgery using the low-temperature plasma radiofrequency for nasopharyngeal angiofibroma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Jul;45(7):578-81
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  • [Title] [Endoscopic surgery using the low-temperature plasma radiofrequency for nasopharyngeal angiofibroma].
  • OBJECTIVE: To evaluate the feasibility of endoscopic surgery using the low-temperature plasma radiofrequency for nasopharyngeal angiofibroma (NA).
  • CONCLUSIONS: Endoscopic surgery using low-temperature plasma radiofrequency for nasopharyngeal angiofibroma has many advantages such as less bleeding and total tumor removal.
  • It is a minimally invasive surgical method for nasopharyngeal angiofibroma.
  • [MeSH-major] Angiofibroma / surgery. Catheter Ablation / methods. Endoscopy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 21055057.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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67. Rosón E, Flórez A, Feal C, De La Torre C, García-Doval I, Abalde T, Cruces M: Progressive nodular histiocytoma associated with thrombocytopenia with absent radii (TAR syndrome) and angiofibromas. Acta Derm Venereol; 2006;86(4):348-50
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  • [Title] Progressive nodular histiocytoma associated with thrombocytopenia with absent radii (TAR syndrome) and angiofibromas.
  • Moreover, the patient had numerous smooth erythematous papules on her chin and around her nose, which were diagnosed histologically as angiofibromas.
  • To our knowledge progressive nodular histiocytoma has not been reported previously associated either with TAR syndrome or with angiofibromas.
  • [MeSH-major] Angiofibroma / complications. Ectromelia / complications. Histiocytoma / pathology. Radius / abnormalities. Skin Diseases / pathology. Thrombocytopenia / complications

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  • (PMID = 16874423.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Databank-accession-numbers] OMIM/ 274000
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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68. Andrade NA, Pinto JA, Nóbrega Mde O, Aguiar JE, Aguiar TF, Vinhaes ES: Exclusively endoscopic surgery for juvenile nasopharyngeal angiofibroma. Otolaryngol Head Neck Surg; 2007 Sep;137(3):492-6
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  • [Title] Exclusively endoscopic surgery for juvenile nasopharyngeal angiofibroma.
  • OBJECTIVE: To present the indications of nasal endoscopic surgery for treating juvenile nasopharyngeal angiofibroma (JNA).
  • According to the classification of Andrews et al, eight patients were stage I and four patients were stage II.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 17765782.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Hanamure Y, Tanaka N, Kawabata T, Kasano F, Kashima N: [Juvenile nasopharyngeal angiofibroma: stage and surgical approach]. Nihon Jibiinkoka Gakkai Kaiho; 2005 May;108(5):513-21
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  • [Title] [Juvenile nasopharyngeal angiofibroma: stage and surgical approach].
  • Juvenile nasopharyngeal angiofibromas (JNAs) are benign tumors that occasionally invade the pterygopalatine fossa, infratemporal fossa, or middle cranial fossa.
  • [MeSH-major] Angiofibroma / pathology. Angiofibroma / surgery. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods

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  • (PMID = 15952338.001).
  • [ISSN] 0030-6622
  • [Journal-full-title] Nihon Jibiinkoka Gakkai kaiho
  • [ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 35
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70. Suzuki M, Sakurai H, Seno S, Hoshi J, Ogawa T, Arikata M, Tojima I, Kitanishi T, Tanaka H, Shimizu T: [Endoscopic resection of benign and malignant tumors in the nasal cavity and paranasal sinus]. Nihon Jibiinkoka Gakkai Kaiho; 2005 Jul;108(7):724-33
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  • [Title] [Endoscopic resection of benign and malignant tumors in the nasal cavity and paranasal sinus].
  • Subjects were patients with benign lesions in the nasal cavity, medial wall of the maxillary sinus, ethmoid sinus, and/or sphenoid sinus without concurrent malignant lesions.
  • Although patients selection for malignant tumor excision was based on (1) possible en bloc resection, (2) low-grade malignant tumors, and (3) tumors in the nasal cavity and adjoining paranasal sinus, the final decision was made individual.
  • Subjects were 23 patients with benign tumor (10 inverted papilloma, 9 hemangioma, 2 juvenile angiofibroma, and 2 other tumors) and 4 with malignant tumor (olfactory neuroblastoma, acinic cell carcinoma, squamous cell carcinoma, and chondroid chordoma) in the nasal and paranasal sinus.
  • The tumor was resected en bloc except for patients with inverted papilloma (2 cases) and chondroid chordoma.
  • Recurrence in benign tumors was zero during a mean observation of 21 months.
  • The endoscopic excision of benign lesions in the nasal and paranasal sinus is thus as effective as conventional radical surgery.

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  • (PMID = 16107047.001).
  • [ISSN] 0030-6622
  • [Journal-full-title] Nihon Jibiinkoka Gakkai kaiho
  • [ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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71. Kapidzić A, Sutalo K: [Surgical treatment of juvenile nasopharyngeal angifibroma]. Med Arh; 2006;60(5):296-7
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  • [Title] [Surgical treatment of juvenile nasopharyngeal angifibroma].
  • [Transliterated title] Operativno lijecenje juvenilnog nazofaringealnog angiofibroma.
  • Juvenile nasopharyngeal angiofibroma represents non-incapsulated benign tumor.
  • Three patients with juvenile nasopharyngeal angiofibroma that underwent surgery in a five year period (2001-2005) at the ENT Clinic of the University Clinical Center in Sarajevo are evaluated in this paper.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 16944730.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] bos
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bosnia and Herzegovina
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72. Baradaranfar MH, Dabirmoghaddam P: Endoscopic endonasal surgery for resection of benign sinonasal tumors: experience with 105 patients. Arch Iran Med; 2006 Jul;9(3):244-9
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  • [Title] Endoscopic endonasal surgery for resection of benign sinonasal tumors: experience with 105 patients.
  • BACKGROUND: The use of endoscopic surgery for nasal and sinus pathologies has revolutionized our approaches towards the diseases of these areas.
  • OBJECTIVE: To report our experience with endoscopic surgery of benign tumors and tumor-like conditions of the nose and paranasal sinuses.
  • METHODS: The medical records of 105 patients with benign sinonasal tumor, who had undergone endoscopic surgery for removal of their neoplasm between 1997 and 2003, were retrospectively studied.
  • RESULTS: The studied patients included 32 with juvenile nasopharyngeal angiofibroma, 24 with inverted papilloma, 23 with benign fibroosseous lesions, 18 with pyogenic granuloma, 6 with intranasal hemangioma, and 2 with pleomorphic adenoma.
  • Eight cases of recurrent tumor--2 angiofibroma, 4 inverted papilloma, 1 fibrous dysplasia, and 1 osteoma--were noted and managed endoscopically alone or in combination with Caldwell-Luc approach.
  • CONCLUSION: Endoscopic surgery is a valuable tool for removal of benign tumors of the nose and paranasal sinuses in the hands of an experienced surgeon.
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / surgery. Adolescent. Adult. Aged. Angiofibroma / diagnosis. Angiofibroma / surgery. Child. Diagnosis, Differential. Female. Follow-Up Studies. Hemangioma / diagnosis. Hemangioma / surgery. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Papilloma, Inverted / diagnosis. Papilloma, Inverted / surgery. Retrospective Studies. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16859060.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Iran
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73. Ladziński P, Majchrzak H, Szymczyk C, Kaspera W, Maliszewski M, Maciejewski A, Wierzgoń J, Majchrzak K, Tymowski M, Adamczyk P: Direct and remote outcome after treatment of tumours involving the subtemporal fossa and related structures with the extended subtemporal approach. Neurol Neurochir Pol; 2010 Mar-Apr;44(2):148-58
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  • The most frequent histological diagnosis was meningioma (16%), followed by angiofibroma, neurinoma and adenocystic carcinoma (12%).
  • [MeSH-minor] Adolescent. Adult. Aged. Angiofibroma / pathology. Angiofibroma / surgery. Carcinoma / pathology. Carcinoma / surgery. Child. Chordoma / pathology. Chordoma / surgery. Female. Fibroma / pathology. Fibroma / surgery. Follow-Up Studies. Humans. Male. Meningioma / surgery. Middle Aged. Neurilemmoma / pathology. Neurilemmoma / surgery. Neurologic Examination. Poland. Skull Base. Treatment Outcome. Young Adult

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  • (PMID = 20496285.001).
  • [ISSN] 0028-3843
  • [Journal-full-title] Neurologia i neurochirurgia polska
  • [ISO-abbreviation] Neurol. Neurochir. Pol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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74. Sołtys J, Pietniczka-Załeska M, Młyńczyk-Budzynowska K, Majkowski J: [Neoplasms of paranasal sinuses in material of ENT Department MSS Hospital in Warsaw between 2006-2007]. Otolaryngol Pol; 2008;62(4):451-4
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  • Tumors of paranasal sinuses present a small percent of tumors detected in the region of head and neck 3-4% and they present a fraction of a percent of tumors in general /0.16%/.
  • THE RESULTS: We detected the following:--benign neoplasms: 2 cases of angiofibroma, 3 cases of inverted papilloma;--malignant tumors: 4 cases of Ca planoepitheliale, 1 instance of adenocarcinoma, 1 instance of Ca anaplasticum, 1--melanoma, 1--esthesioneuroblastoma, 1--lymphoma malignum, 1--metastatic tumor.

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  • (PMID = 18837222.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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75. Wendler O, Schäfer R, Schick B: Mast cells and T-lymphocytes in juvenile angiofibromas. Eur Arch Otorhinolaryngol; 2007 Jul;264(7):769-75
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  • [Title] Mast cells and T-lymphocytes in juvenile angiofibromas.
  • Juvenile angiofibroma (JA) is regarded as a benign fibrovascular tumour of unknown aetiology.
  • Due to its fibrovascular architecture the fibrous and vascular tumour component have been in the focus of most studies.
  • Western blot analysis supported finding of remarkable expression of the mast cell markers tryptase and chymase in JAs and indicated for both proteins similar but also different molecular weights than being observed in NM.
  • Regarding these observations JAs are certainly not only built up by vascular cells and fibrous stroma cells.
  • [MeSH-major] Angiofibroma / pathology. CD4-Positive T-Lymphocytes / pathology. CD8-Positive T-Lymphocytes / pathology. Mast Cells / pathology. Nose Neoplasms / pathology

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  • (PMID = 17310347.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.21.39 / Chymases; EC 3.4.21.59 / Tryptases
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76. Tasca I, Compadretti GC: Extranasopharyngeal angiofibroma of nasal septum. A controversial entity. Acta Otorhinolaryngol Ital; 2008 Dec;28(6):312-4
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  • [Title] Extranasopharyngeal angiofibroma of nasal septum. A controversial entity.
  • The term extranasopharyngeal angiofibroma has been applied to vascular, fibrous nodules occurring outside the nasopharynx.
  • Typically, clinical characteristics of extranasopharyngeal angiofibromas do not conform with that of nasopharyngeal angiofibromas and, for this reason, these tumours must be regarded as a separate entity.
  • Due to these different features, extranasopharyngeal angiofibromas can present a diagnostic challenge and a meticulous evaluation with a high index of suspicion is essential in establishing the correct diagnosis and treatment.
  • We report the case of a 57-year-old female with a 1-year history of a slowly progressing right nasal obstruction due to the presence of a whitish mass adhering to the posterior nasal septum.
  • Histopathological findings were compatible with a diagnosis of angiofibroma.
  • Extranasopharyngeal angiofibroma must be taken into consideration in the differential diagnosis of nasal vascular tumours and nasal septum should be regarded as a potential, though exceptional, localization of these neoplasms.
  • [MeSH-major] Angiofibroma. Nasal Septum. Nose Neoplasms

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  • (PMID = 19205598.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2689538
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77. Amin AA: Maxillary swing approach for surgical resection of recurrent nasopharyngeal tumors. J Egypt Natl Canc Inst; 2007 Sep;19(3):219-23
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  • The nasopharynx, para-pharyngeal space and infratemporal fossa are now exposed facilitating complete resection of the tumor.
  • Three patients had recurrent carcinoma of the nasopharynx after primary radiation therapy, while four patients had locally advanced recurrent juvenile nasopharyngeal angiofibroma (JNA).
  • The follow-up period ranged from 3 months to 6 years, one patient died from distant disease and another patient is alive with residual intra-cranial disease.
  • The maxillary swing approach allows safe and complete resection for nasopharyngeal carcinoma as well as juvenile angiofibroma with intracranial extension.
  • Key Words : Recurrent nasopharyngeal tumors -Salvage nasopharyngectomy -Juvenile nasopharyngeal angiofibroma.

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  • (PMID = 19190695.001).
  • [ISSN] 1110-0362
  • [Journal-full-title] Journal of the Egyptian National Cancer Institute
  • [ISO-abbreviation] J Egypt Natl Canc Inst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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78. Türkmen M, Ertam I, Unal I, Dereli T: Facial angiofibromas of tuberous sclerosis: successful treatment with podophyllin. J Eur Acad Dermatol Venereol; 2009 Jun;23(6):713-4
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  • [Title] Facial angiofibromas of tuberous sclerosis: successful treatment with podophyllin.
  • [MeSH-major] Angiofibroma / drug therapy. Face. Podophyllin / therapeutic use. Tuberous Sclerosis / complications

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  • (PMID = 18785889.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 9000-55-9 / Podophyllin
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79. Bockmühl U, Minovi A, Kratzsch B, Hendus J, Draf W: [Endonasal micro-endoscopic tumor surgery: state of the art]. Laryngorhinootologie; 2005 Dec;84(12):884-91
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  • BACKGROUND: The aim of the present study was to establish the efficacy of endonasal micro-endoscopic surgery for removal of benign and malignant neoplastic lesions of the paranasal sinuses and the anterior skull base.
  • MATERIAL AND METHODS: This retrospective study evaluated 350 patients with tumors of the paranasal sinuses and the anterior skull base (215 benign and 135 malignant tumors) that were treated surgically at the ENT-Department of the Hospital Fulda gAG between 1993 and 2003.
  • RESULTS: Most frequent entities of benign tumors were osteomas, inverted papillomas and juvenile angiofibromas.
  • 54 % of the benign (n = 118) and 41 % of the malignant tumors (n = 54) were resected exclusively via the endonasal micro-endoscopic approach.
  • Within the follow-up period 3 recurrencies were observed, two inverted papillomas (one was operated endonasally) and one juvenile angiofibroma.
  • In the malignoma group 34 patients died because of tumor disease (16 cases due to recurrencies, 18 cases due to metastases formation).
  • The 5 year survival rate was 66.4 % with respect to the disease-specific survival.
  • The Kaplan-Meier analysis revealed statistically significant differences for the pT stage: pT2 and pT3 tumors have had a 5-year disease-specific survival of 92.3 % and 83.8 %, respectively, compared to 61.5 % of the pT4 tumors.
  • Disease-specific survival also showed differences dependent on histology, tumor site and occurrence, but was without proven significancy.
  • In the patient subgroup who suffered from adenocarcinoma, squamous cell carcinoma or esthesioneuroblastoma the 5-year disease-specific survival was 78.4 % of 29 patients after endonasal resection compared to 66.4 % in 51 patients operated via an external approach.
  • CONCLUSION: The advances in endonasal micro-endoscopic surgery also allow a safe and effective removal of benign and malignant anterior skull base tumors with low morbidity.
  • [MeSH-minor] Disease-Free Survival. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Reoperation. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 16358197.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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80. Cansiz H, Güvenç MG, Sekercioğlu N: Surgical approaches to juvenile nasopharyngeal angiofibroma. J Craniomaxillofac Surg; 2006 Jan;34(1):3-8
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  • [Title] Surgical approaches to juvenile nasopharyngeal angiofibroma.
  • INTRODUCTION: Juvenile nasopharyngeal angiofibromas are highly vascular, non-encapsulated tumours affecting predominantly young males.
  • These lesions are benign histologically but they may become life-threatening with excessive bleeding or intracranial extension.
  • MATERIAL AND METHODS: The surgical approaches to 22 male patients with nasopharyngeal angiofibromas are reviewed.
  • CONCLUSION: The suggested treatment of juvenile nasopharyngeal angiofibroma consists of an endoscopic transnasal approach for early stage lesions, and a modified midfacial degloving for almost all of the advanced lesions.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Oral Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Carotid Artery Injuries / etiology. Carotid Artery, Internal / pathology. Child. Craniotomy / adverse effects. Endoscopy. Facial Paralysis / etiology. Frontal Bone / surgery. Humans. Male. Neoplasm Staging. Nose / surgery. Nose Diseases / etiology. Paresthesia / etiology. Postoperative Complications. Retrospective Studies. Rupture. Temporal Bone / surgery. Treatment Outcome

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  • (PMID = 16343920.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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81. Rzaev RM: [Surgical policy in patients with basally advanced form of juvenile nasopharyngeal angiofibroma]. Vestn Otorinolaringol; 2005;(3):29-33
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  • [Title] [Surgical policy in patients with basally advanced form of juvenile nasopharyngeal angiofibroma].
  • The authors has modified surgical policy in a basicranially extending form of juvenile nasopharyngeal angiofibroma (JNA) which is classified into tumors of stage I, II and III.
  • [MeSH-major] Angiofibroma. Nasopharyngeal Neoplasms. Otorhinolaryngologic Surgical Procedures / methods

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  • (PMID = 16034343.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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82. Li Z, Lin G, He L, Yi Z: [Perioperative managements of huge lobulated nasopharyngeal angiofibromas with intracranial extensions]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Jul;22(14):639-41
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  • [Title] [Perioperative managements of huge lobulated nasopharyngeal angiofibromas with intracranial extensions].
  • OBJECTIVE: To summarize our experience of successful and failed management in 8 huge lobulated nasopharyngeal angiofibromas with intracranial extensions, and introduce some key points of perioperative treatments.
  • [MeSH-major] Angiofibroma / surgery. Brain Neoplasms / surgery. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18841793.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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83. Batra PS, Citardi MJ: Endoscopic management of sinonasal malignancy. Otolaryngol Clin North Am; 2006 Jun;39(3):619-37, x-xi
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  • The advent of rigid telescopes has revolutionized the management of rhinologic disease.
  • These instruments have been used as a diagnostic and therapeutic tool for paranasal sinus inflammatory diseases since the 1970s.
  • Recently, endoscopic techniques have also been used successfully to manage selected tumors, including inverted papilloma, angiofibromas, and hypophyseal tumors.

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  • (PMID = 16757235.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 31
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84. Schuon R, Brieger J, Heinrich UR, Roth Y, Szyfter W, Mann WJ: Immunohistochemical analysis of growth mechanisms in juvenile nasopharyngeal angiofibroma. Eur Arch Otorhinolaryngol; 2007 Apr;264(4):389-94
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  • [Title] Immunohistochemical analysis of growth mechanisms in juvenile nasopharyngeal angiofibroma.
  • Angiogenic factors are discussed to participate in growth and promotion of juvenile nasopharyngeal angiofibroma (JNA).
  • [MeSH-major] Angiofibroma. Fibroblast Growth Factor 2 / immunology. Hypoxia-Inducible Factor 1, alpha Subunit / immunology. Lymphotoxin-alpha / immunology. Nasopharyngeal Neoplasms. Vascular Endothelial Growth Factor Receptor-1 / immunology. Vascular Endothelial Growth Factor Receptor-2 / immunology

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  • (PMID = 17177025.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Lymphotoxin-alpha; 103107-01-3 / Fibroblast Growth Factor 2; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-1; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2
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85. Hofmann V, Holzhausen HJ, Koesling S, Knipping S: Sinonasal hemangiopericytoma. Rev Laryngol Otol Rhinol (Bord); 2010;131(4-5):313-5
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  • CASE REPORT: A case of a 76-year-old female patient is presented.
  • The former histological diagnosis was stated as "angiofibroma with signs of proliferation ".
  • Just additional immunocytochemistry revealed the finding of primitive mesenchymal cells.
  • This confirmed the diagnosis of a hemangiopericytoma.

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  • (PMID = 21866748.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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86. Peces R, Peces C, Cuesta-López E, Pérez-Dueñas V, Vega-Cabrera C, Azorín S, Selgas R: Low-dose rapamycin reduces kidney volume angiomyolipomas and prevents the loss of renal function in a patient with tuberous sclerosis complex. Nephrol Dial Transplant; 2010 Nov;25(11):3787-91
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  • There was also a reduction of facial angiofibromas, improvement of blood pressure control and absence of AML bleeding over this time period.
  • To the best of our knowledge, this is the first report of a case of reduction in renal AML volume together with preservation of renal function in a patient with TSC receiving low-dose rapamycin.

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  • (PMID = 20663789.001).
  • [ISSN] 1460-2385
  • [Journal-full-title] Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • [ISO-abbreviation] Nephrol. Dial. Transplant.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.7.1.1 / TOR Serine-Threonine Kinases; W36ZG6FT64 / Sirolimus
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87. Ordóñez-Ordóñez LE, Vergara-Hernández JC, Silva-Rueda R: [Juvenile nasopharyngeal angiofibroma: an atypical case]. Acta Otorrinolaringol Esp; 2008 Oct;59(8):424
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  • [Title] [Juvenile nasopharyngeal angiofibroma: an atypical case].
  • [Transliterated title] Angiofibroma nasofaríngeo juvenil: un caso atípico.
  • [MeSH-major] Angiofibroma / radiography. Angiofibroma / surgery. Endoscopy / methods. Nasopharyngeal Neoplasms / radiography. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 18928680.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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88. Zoumalan CI, Egbert PR, Warwar RE, McCulley TJ: Orbital giant cell angiofibroma recurring as a solitary fibrous tumor. Ophthal Plast Reconstr Surg; 2008 Jul-Aug;24(4):325-7
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  • [Title] Orbital giant cell angiofibroma recurring as a solitary fibrous tumor.
  • Giant cell angiofibroma has recently been hypothesized to be a clinicopathologic variant of solitary fibrous tumor.
  • The authors report a case of an orbital giant cell angiofibroma that recurred as a solitary fibrous tumor 4 years later.
  • The report strongly supports the hypothesis that giant cell angiofibroma and solitary fibrous tumor are related.
  • [MeSH-major] Angiofibroma / pathology. Giant Cells / pathology. Neoplasm Recurrence, Local / pathology. Orbital Neoplasms / pathology. Solitary Fibrous Tumors / pathology

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  • (PMID = 18645449.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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89. Jabbour SA, Davidovici BB, Wolf R: Rare syndromes. Clin Dermatol; 2006 Jul-Aug;24(4):299-316
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  • Dermatologists may also encounter patients presenting with skin lesions that reflect an underlying endocrine disorder not commonly seen in daily practice.
  • McCune-Albright syndrome is characterized by café-au-lait spots, polyostotic fibrous dysplasia, sexual precocity, and hyperfunction of multiple endocrine glands.
  • Multiple endocrine neoplasia type 2A is characterized by medullary thyroid cancer, pheochromocytoma, and primary parathyroid hyperplasia.
  • Multiple endocrine neoplasia type 1 is an autosomal dominant predisposition to tumors of the parathyroid glands (four-gland hyperplasia), anterior pituitary, and pancreatic islet cells; hence, the mnemonic device of the "3 Ps"; multiple cutaneous lesions (angiofibromas and collagenomas) are frequent in patients with multiple endocrine neoplasia type 1.
  • Carney complex may be viewed as a form of multiple endocrine neoplasia because affected patients often have tumors of two or more endocrine glands, including primary pigmented nodular adrenocortical disease (some with Cushing's syndrome), pituitary adenoma, testicular neoplasms, thyroid adenoma or carcinoma, and ovarian cysts.
  • Mast cell diseases include all disorders of mast cell proliferation.
  • These diseases can be limited to the skin, referred to as "cutaneous mastocytosis," or involve extracutaneous tissues, called "systemic mastocytosis."
  • [MeSH-major] Endocrine System Diseases / genetics. Endocrine System Diseases / pathology. Mastocytosis, Cutaneous / pathology. Multiple Endocrine Neoplasia / genetics. Multiple Endocrine Neoplasia / pathology

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  • (PMID = 16828412.001).
  • [ISSN] 0738-081X
  • [Journal-full-title] Clinics in dermatology
  • [ISO-abbreviation] Clin. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 155
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90. Pires CF, Anunciação GM, De Sousa WL, Santos BM, Anunciação FA, Pires AF, Pires LF: [Tuberous sclerosis in childhood]. Dermatol Online J; 2008;14(9):14
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  • Tuberous sclerosis is an autosomal dominant disease that results from mutations in one of two tumor suppressor genes, TSC1 and TSC2.
  • We are reporting a two-year-old girl who presented with hypopigmented macules (ash leaf) in the skin and small erythematous facial papules (angiofibromas).
  • Although the signs of tuberous sclerosis were specifically looked for in this patient because of her mother, subtle angiofibromas in a young child can be easily missed.
  • [MeSH-major] Angiofibroma / etiology. Facial Neoplasms / etiology. Tuberous Sclerosis / diagnosis


91. Kandil DH, Kida M, Laub DR, Cooper K: Sarcomatous transformation in a cellular angiofibroma: a case report. J Clin Pathol; 2009 Oct;62(10):945-7
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  • [Title] Sarcomatous transformation in a cellular angiofibroma: a case report.
  • Cellular angiofibroma is a rare benign mesenchymal tumour of middle-aged adults.
  • This report describes the case of a patient with a 3.5 cm subcutaneous mass, 2 cm below the left anterior superior iliac spine.
  • This is believed to be the first reported case of sarcomatous transformation in a cellular angiofibroma.
  • [MeSH-major] Angiofibroma / pathology. Sarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Disease Progression. Fatal Outcome. Humans. Neoplasms, Second Primary

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  • (PMID = 19783726.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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92. Cherekaev VA, Belov AI, Kulikovskiĭ PV, Arustamian SR: [Juvenile angiofibroma predominantly extending into the middle cranial fossa and eye-socket]. Zh Vopr Neirokhir Im N N Burdenko; 2006 Jan-Mar;(1):37-9; discussion 39-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Juvenile angiofibroma predominantly extending into the middle cranial fossa and eye-socket].
  • The paper analyzes a rare case of juvenile angiofibroma primarily locating in the infratemporal and middle cranial fossa without a nodule in the nasopharynx.
  • Since the disease has started from right facial hypesthesia, neurinoma involving the first and second branches of the trigeminal nerve and spreading to the eye-socket may be suggested.
  • [MeSH-major] Angiofibroma / diagnosis. Angiofibroma / surgery. Skull Base Neoplasms / diagnosis. Skull Base Neoplasms / surgery

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  • (PMID = 16739934.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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93. Ahmad R, Ishlah W, Azilah N, Rahman JA: Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization. Asian J Surg; 2008 Oct;31(4):174-8
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  • [Title] Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm that occurs almost exclusively in the nasopharynx of adolescent males.

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  • (PMID = 19010758.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] China
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94. Maggiani F, Debiec-Rychter M, Vanbockrijck M, Sciot R: Cellular angiofibroma: another mesenchymal tumour with 13q14 involvement, suggesting a link with spindle cell lipoma and (extra)-mammary myofibroblastoma. Histopathology; 2007 Sep;51(3):410-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cellular angiofibroma: another mesenchymal tumour with 13q14 involvement, suggesting a link with spindle cell lipoma and (extra)-mammary myofibroblastoma.
  • [MeSH-major] Angiofibroma / pathology. Chromosome Deletion. Chromosomes, Human, Pair 13 / genetics. Mesoderm / pathology

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  • (PMID = 17727484.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Desmin; 0 / Retinoblastoma Protein
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95. Llorente JL, Nazar G, Cabanillas R, Fernández de León R, Suárez C: Subtemporal-preauricular approach in the management of infratemporal and nasopharyngeal tumours. J Otolaryngol; 2006 Jun;35(3):173-9
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  • There were 19 benign lesions and 21 malignant tumours, the most common being nasopharyngeal carcinomas, juvenile angiofibromas, and adenoid-cystic carcinomas.
  • Most of the tumours were at an advanced stage, with skull base involvement in 13 benign tumours and in 14 malignant ones.
  • All 19 patients with benign tumours are alive, although 5 of them (26%) presented with residual or recurrent disease.

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  • (PMID = 16929993.001).
  • [ISSN] 0381-6605
  • [Journal-full-title] The Journal of otolaryngology
  • [ISO-abbreviation] J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
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96. Rödder K, Wintzer HO, Fisch M: [Solitary tumor of the spermatic cord]. Aktuelle Urol; 2007 Mar;38(2):152-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histologically a cellular angiofibroma was diagnosed.
  • These benign tumours are very rare.
  • [MeSH-major] Angiofibroma. Genital Neoplasms, Male. Spermatic Cord

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  • (PMID = 17390279.001).
  • [ISSN] 0001-7868
  • [Journal-full-title] Aktuelle Urologie
  • [ISO-abbreviation] Aktuelle Urol
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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97. Lin C, Li ZC, Cheng JM, Lin GB, Zhou AD, Yi ZX: [Pathological features and clinical managements of nasopharyngeal angiofibroma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Oct;43(10):763-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pathological features and clinical managements of nasopharyngeal angiofibroma].
  • OBJECTIVE: To study the pathological features of nasopharyngeal angiofibroma (NA) and the principles for clinical managements.
  • The tumor extensions such as in pterygopalatine fossa and infratemporal fossa were covered by fibrous pseudocapsule.
  • CONCLUSIONS: nasopharyngeal angiofibroma is covered by epithelium or pseudo-capsule, it does not infiltrate the surrounding tissue.
  • [MeSH-major] Angiofibroma / pathology. Nasopharyngeal Neoplasms / pathology

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  • (PMID = 19119673.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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98. Swaroop Mr, Nischal Kc, Rajesh Gowda Cm, Umashankar Nu, Basavaraj Hb, Sathyanarayana Bd: Radiofrequency ablation of adenoma sebaceum. J Cutan Aesthet Surg; 2008 Jul;1(2):89-91
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  • Histologically, they are angiofibromas that occur over the central part of the face and hence, cause a major cosmetic disfigurement.

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  • (PMID = 20300351.001).
  • [ISSN] 0974-5157
  • [Journal-full-title] Journal of cutaneous and aesthetic surgery
  • [ISO-abbreviation] J Cutan Aesthet Surg
  • [Language] eng
  • [Publication-type] Journal Article
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  • [Other-IDs] NLM/ PMC2840910
  • [Keywords] NOTNLM ; Adenoma sebaceum / disfigurement / radiofrequency / tuberous sclerosis
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99. Das S, Kirsch CF: Imaging of lumps and bumps in the nose: a review of sinonasal tumours. Cancer Imaging; 2005;5:167-77
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  • Sinonasal disease is one of the most common clinical head and neck pathologies.
  • Although sinus tumours are rare, they portend a poor prognosis, often due to advanced disease at diagnosis.
  • Like most neoplasms, early detection improves prognosis, therefore clinicians and radiologists should be aware of features separating tumours from inflammatory sinus disease.
  • Benign neoplasms reviewed include osteoma, inverting papilloma, and juvenile nasal angiofibroma.

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  • [Copyright] International Cancer Imaging Society.
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  • (PMID = 16361146.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 73
  • [Other-IDs] NLM/ PMC1665243
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100. Szyfter W, Borucki Ł, Balcerowiak A: [Endoscopic surgery for selected tumors of the nose and paranasal sinuses--practical sense of the four hands technique]. Otolaryngol Pol; 2008;62(2):170-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Two major pathologies are present in the literature, the inverted papilloma and the angiofibroma.

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  • (PMID = 18637441.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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