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Items 1 to 100 of about 525
1. Bhatia A, Nada R, Kumar Y, Menon P: Dabska tumor (endovascular papillary angioendothelioma) of testis: a case report with brief review of literature. Diagn Pathol; 2006;1:12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dabska tumor (endovascular papillary angioendothelioma) of testis: a case report with brief review of literature.
  • The Dabska tumor also known as Endovascular papillary angioendothelioma is a rare type of hemangioendothelioma characterized by intraluminal papillary endothelial structures.

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  • [Cites] Arch Pathol Lab Med. 1997 Sep;121(9):992-5 [9302935.001]
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  • (PMID = 16859564.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1555613
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2. Ward KA, Ecker PM, White RR, Melnik TE, Gulbahce EH, Wilke MS, Sangueza OP: Papillary intralymphatic angioendothelioma of the thigh: A case report and review of the literature. Dermatol Online J; 2010;16(4):4
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papillary intralymphatic angioendothelioma of the thigh: A case report and review of the literature.
  • Other low-grade forms of angiosarcoma, including papillary intralymphatic angioendothelioma, also known as Dabska tumor, are less invasive, affect a wider age range, and offer a better prognosis.
  • There are several predisposing factors that increase the risk of angiosarcoma and include chronic lymphedema of the extremities, preexisting vascular lesions, and prior radiation, often as therapy for other malignancies.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Skin Neoplasms / diagnosis. Thigh
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 20409411.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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3. Ploegmakers MJ, Pruszczynski M, De Rooy J, Kusters B, Veth RP: Angiosarcoma with malignant peripheral nerve sheath tumour developing in a patient with klippel-trénaunay-weber syndrome. Sarcoma; 2005;9(3-4):137-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Our patient underwent an above-knee amputation for biopsy-proven malignant vascular tumour, first thought to be a composite hemangio-endothelioma and/or angiosarcoma with lung metastases.
  • RESULTS: In the amputated extremity, a vascular malformation was found with tumour showing various components with foci of angiosarcoma adjacent to diffuse neurofibroma and areas with high-grade malignant peripheral nerve sheath tumour.

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  • (PMID = 18521421.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2395629
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4. Azcárate Perea L, Oliveros Acebes E, Moreno Mata N, Salomón Pérez R, Vilalta Castel E, González Aragoneses F: [Pulmonary epithelioid hemangioendothelioma]. Arch Bronconeumol; 2009 Sep;45(9):466-8
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  • [Title] [Pulmonary epithelioid hemangioendothelioma].
  • [Transliterated title] Hemangioendotelioma epiteloide pulmonar.
  • Epithelioid hemangioendothelioma is a multifocal tumor that rarely metastasizes.
  • It is difficult to diagnose and is most often an incidental finding in young asymptomatic women.
  • We report the case of a 73-year-old woman in whom multiple pulmonary nodules detected by chance in a radiograph were subsequently diagnosed as epithelioid hemangioendothelioma.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / radiography. Lung Neoplasms / radiography. Neoplasms, Multiple Primary / radiography

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  • [CommentIn] Arch Bronconeumol. 2010 Feb;46(2):103-4 [19819604.001]
  • (PMID = 19403224.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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5. Chan YF, Kumar B, Auldist A, Waters K: Myoid angioendothelioma of the spleen in a child after successful treatment of a Wilms' tumour. Pathology; 2005 Apr;37(2):181-4
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  • [Title] Myoid angioendothelioma of the spleen in a child after successful treatment of a Wilms' tumour.
  • [MeSH-major] Hemangioendothelioma / pathology. Kidney Neoplasms / therapy. Neoplasms, Second Primary / pathology. Splenic Neoplasms / pathology. Wilms Tumor / therapy
  • [MeSH-minor] Biomarkers, Tumor / analysis. Child, Preschool. Endothelium, Vascular / pathology. Humans. Immunohistochemistry. Male. Stromal Cells / chemistry. Stromal Cells / pathology. Stromal Cells / ultrastructure. Treatment Outcome

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  • (PMID = 16028853.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 11
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6. López Gutiérrez JC, Patrón Romero M: [Thoracic kaposiform hemangioendothelioma. Four consecutive cases with distinct outcome]. An Pediatr (Barc); 2005 Jul;63(1):72-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Thoracic kaposiform hemangioendothelioma. Four consecutive cases with distinct outcome].
  • [Transliterated title] Hemangioendotelioma kaposiforme torácico. Cuatro casos con evolución variable.
  • INTRODUCTION: Kaposiform hemangioendothelioma (KHE) is a rare, frequently congenital, neoplasm associated with the Kasabach-Merritt phenomenon (KMP) and predilection for the trunk.
  • As little is known about the pathogenesis of these highly aggressive vascular tumors, further molecular research is needed to understand their long-term behavior.
  • [MeSH-major] Hemangioendothelioma. Thoracic Neoplasms

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  • (PMID = 15989875.001).
  • [ISSN] 1695-4033
  • [Journal-full-title] Anales de pediatría (Barcelona, Spain : 2003)
  • [ISO-abbreviation] An Pediatr (Barc)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Interferon-alpha; 0 / Recombinant Proteins; 76543-88-9 / interferon alfa-2a
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7. Mishra A, Tripathy K, Bhuyan P, Mohanty P, Rath J, Mohanty R: Endovascular papillary angioendothelioma in an elderly female. Indian J Pathol Microbiol; 2006 Jul;49(3):392-3
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  • [Title] Endovascular papillary angioendothelioma in an elderly female.
  • Endovascular papillary angioendothelioma (EPA) is a rare vascular tumor of low grade malignancy, encountered primarily in children.
  • Histomorphology revealed anastomosing lymphatic channels showing intraluminal papillary fronds with hyaline vascular cores and hobnailing of endothelial cells.
  • A diagnosis of EPA was made based on this picture.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Hemangioendothelioma / diagnosis. Neck / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 17001894.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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8. Komatsu Y, Koizumi T, Yasuo M, Urushihata K, Yamamoto H, Hanaoka M, Kubo K, Kawakami S, Honda T, Fujimoto K, Hachiya T: Malignant hepatic epithelioid hemangioendothelioma with rapid progression and fatal outcome. Intern Med; 2010;49(12):1149-53
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  • [Title] Malignant hepatic epithelioid hemangioendothelioma with rapid progression and fatal outcome.
  • Based on these observations, a diagnosis of hemangioendothelioma (EHE), a rare vascular tumor, was made.
  • [MeSH-major] Disease Progression. Hemangioendothelioma, Epithelioid / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Fatal Outcome. Female. Humans. Lung Neoplasms / diagnosis. Lung Neoplasms / secondary. Middle Aged. Time Factors

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  • (PMID = 20558933.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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9. Rodgers B, Zeim S, Crawford B, Neitzschman H, Daroca P, Scher CD: Splenic papillary angioendothelioma in a 6-year-old girl. J Pediatr Hematol Oncol; 2007 Dec;29(12):808-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Splenic papillary angioendothelioma in a 6-year-old girl.
  • Papillary angioendothelioma is a rare, low-grade neoplasm of lymphatic channels that usually presents intradermally.
  • We report the case of a 6-year-old girl with isolated splenomegaly and symptoms of early satiety and weight loss, whom was found to have a splenic papillary angioendothelioma.
  • Subsequent surgery and pathologic assessment revealed a papillary angioendothelioma (Dabska tumor) within lymphatic spaces.
  • [MeSH-major] Hemangioendothelioma / radiography. Hemangioendothelioma / surgery. Splenic Neoplasms / radiography. Splenic Neoplasms / surgery

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  • (PMID = 18090926.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Fiorillo A, DeRosa G, Giugliano F, DeLillo ML, Sabbatino MS, Veneziano A: Efficacy of pegylated lyposomal anthracyclines and of intra-arterial carboplatin and doxorubicin combined with local hyperthermia in a case of malignant endovascular papillary angioendothelioma. Curr Drug Deliv; 2009 Jan;6(1):58-61
Hazardous Substances Data Bank. CARBOPLATIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Efficacy of pegylated lyposomal anthracyclines and of intra-arterial carboplatin and doxorubicin combined with local hyperthermia in a case of malignant endovascular papillary angioendothelioma.
  • Malignant vascular tumors are exceedingly rare in childhood.
  • We observed the case of a 4-year-old boy affected by malignant endovascular papillary angioendothelioma, a rare vascular tumor of intermediate malignancy, involving all his left leg and partially the pelvis.
  • This experience probably represents the first step toward an effective treatment of malignant vascular tumors in infancy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Papillary / therapy. Doxorubicin / analogs & derivatives. Hemangioendothelioma / therapy. Hyperthermia, Induced. Polyethylene Glycols / therapeutic use. Vascular Neoplasms / therapy

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  • (PMID = 19418956.001).
  • [ISSN] 1567-2018
  • [Journal-full-title] Current drug delivery
  • [ISO-abbreviation] Curr Drug Deliv
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United Arab Emirates
  • [Chemical-registry-number] 0 / liposomal doxorubicin; 30IQX730WE / Polyethylene Glycols; 80168379AG / Doxorubicin; BG3F62OND5 / Carboplatin
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11. Goertz O, Lehnhardt M, Hirsch T, Stricker I, Steinau HU, Homann HH: [Functional reconstruction of the superficial posterior compartment of the leg after tumour ablation in an infant]. Handchir Mikrochir Plast Chir; 2009 Aug;41(4):244-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 33-month-old female child was diagnosed with a papillary intralymphatic angioendothelioma, a rare type of low-grade angiosarcoma, on the dorsal lower leg.
  • [MeSH-major] Hemangioendothelioma / surgery. Leg / surgery. Microsurgery / methods. Muscle, Skeletal / surgery. Soft Tissue Neoplasms / surgery. Surgical Flaps / blood supply. Surgical Flaps / innervation

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  • [Copyright] Georg Thieme Verlag KG Stuttgart * New York.
  • (PMID = 19688654.001).
  • [ISSN] 1439-3980
  • [Journal-full-title] Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deutschen Plastischen Chirurgen
  • [ISO-abbreviation] Handchir Mikrochir Plast Chir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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12. Requena L, Luis Díaz J, Manzarbeitia F, Carrillo R, Fernández-Herrera J, Kutzner H: Cutaneous composite hemangioendothelioma with satellitosis and lymph node metastases. J Cutan Pathol; 2008 Feb;35(2):225-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous composite hemangioendothelioma with satellitosis and lymph node metastases.
  • The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas).
  • Thus, within the spectrum of hemangioendothelioma have been successively included epithelioid hemangioendothelioma, spindle cell hemangioendothelioma, retiform hemangioendothelioma, kaposiform hemangioendothelioma, polymorphous hemagioendothelioma of the lymph nodes, papillary intralymphatic angioendothelioma (PILA) and composite hemangioendothelioma.
  • The latter is a vascular neoplasm showing varying combinations of benign, low-grade malignant and malignant vascular components.
  • We herein report a case of composite hemangioendothelioma showing a combination of retiform hemangioendothelioma, epithelioid hemangioendothelioma, spindle cell hemangioma and PILA.
  • The neoplasm showed a more aggressive behavior than other reported cases of composite hemangioendothelioma and it developed satellitosis and metastases to the inguinal lymph nodes.
  • [MeSH-major] Foot Diseases / pathology. Hemangioendothelioma / pathology. Leg / pathology. Lymphatic Metastasis / pathology. Skin Neoplasms / pathology

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  • (PMID = 18190450.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / Tumor Suppressor Proteins; 0 / prospero-related homeobox 1 protein
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13. de Wind A, Meert V, Chahidi N, Theunis A, Somerhausen Nde S: [Retiform haemangioendothelioma: a case report]. Ann Pathol; 2009 Dec;29(6):491-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Retiform haemangioendothelioma: a case report].
  • Retiform haemangioendothelioma is a locally aggressive, very rarely metastasizing vascular lesion.
  • Histologically, it is characterized by distinctive arborizing blood vessels resembling "rete testis" and lined by endothelial cells with characteristic hobnail morphology.
  • We discuss the classification of hemangioendotheliomas.
  • The term hemangioendothelioma should be restricted to vascular tumours of "intermediate malignancy" but has been used to designate tumours with variable histological features and clinical behaviour.
  • Spindle cell hemangio(endothelio)ma is currently regarded as a benign reactive lesion.
  • Kaposiform hemangioendothelioma is potentially lethal due to consumption coagulopathy but no metastasizing case has been reported.
  • Epithelioid hemangioendothelioma is associated with a significant metastatic risk and has been included in the category of malignant vascular tumors.
  • The vascular lesions fulfilling the strict definition of hemangioendothelioma include retiform hemangioendothelioma, papillary intralymphatic angioendothelioma "Dabska's tumor", composite hemangioendothelioma and perhaps the controversial polymorphic hemangioendothelioma.
  • [MeSH-major] Hemangioendothelioma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Antigens, CD / analysis. Antigens, CD31 / analysis. Antigens, CD34 / analysis. Endothelium, Vascular / pathology. Humans. Male. Middle Aged. Neoplasm Metastasis. Tibia / pathology. Vascular Neoplasms / pathology

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  • (PMID = 20005438.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD31; 0 / Antigens, CD34
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14. Bölke E, Gripp S, Peiper M, Budach W, Schwarz A, Orth K, Reinecke P, van de Nes JA: Multifocal epithelioid hemangioendothelioma: case report of a clinical chamaeleon. Eur J Med Res; 2006 Nov 30;11(11):462-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multifocal epithelioid hemangioendothelioma: case report of a clinical chamaeleon.
  • Epithelioid hemangioendothelioma is an extremely rare vascular bone tumor with a slow growth and poor prognosis.
  • Various synonyms for epithelioid hemangioendothelioma are used clinically: low grade anaplastic angiosarcoma, cellular hemangioma, histiocytoid hemangioma and angioendothelioma.
  • However, it represents 1% of all vascular neoplasms and is locally aggressive.
  • We report the course of disease of a 47-year-old man who presented to our clinic with unspecific abdominal and back pain.
  • Tumor histology of the bone and liver biopsies confirmed the diagnosis of epithelioid hemangioendothelioma.
  • Although treatment was initiated with thalidomide, the patient developed multiple organ dysfunction syndrome (MODS) and succumbed to his disease.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / pathology. Liver Neoplasms / pathology. Spinal Neoplasms / pathology. Splenic Neoplasms / pathology
  • [MeSH-minor] Angiogenesis Inhibitors / therapeutic use. Diagnosis, Differential. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Syndrome. Thalidomide / therapeutic use. Tomography, X-Ray Computed

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  • (PMID = 17182357.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 4Z8R6ORS6L / Thalidomide
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15. Antosz Z, Zaniewski M, Kostecki J, Poreba R: Angiosarcoma arising within a Malignant Endovascular Papillary Angioendothelioma (Dabska tumor). Neuro Endocrinol Lett; 2010;31(4):454-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma arising within a Malignant Endovascular Papillary Angioendothelioma (Dabska tumor).
  • We report an angiosarcoma arising within a malignant endovascular papillary angioendothelioma (Dabska tumor) in soft tissue of the upper thigh/buttock of a 42-year-old woman.
  • Although neoplastic progression within a vascular tumor of an existing low-grade lesion into DT has been described so far, we seem to be the first to report transformation of DT into an angiosarcoma.
  • [MeSH-major] Hemangioendothelioma / pathology. Hemangiosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 20802459.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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16. Schilling G, Schuch G, Panse JP, Sterneck M, Bokemeyer C: Activity of lenalidomide in metastatic hepatic epithelioid hemangioendothelioma (HEH): A case report. J Clin Oncol; 2009 May 20;27(15_suppl):e21527

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Activity of lenalidomide in metastatic hepatic epithelioid hemangioendothelioma (HEH): A case report.
  • Surgical resection or liver transplantation is recommended in locally advanced disease and has been successfully performed in selected cases with extrahepatic manifestations.
  • Disease progressed during first line treatment with adriamycin and ifosfamide (2 cycles given).
  • Retrospective analysis after 9 cycles demonstrated stable disease in comparison to the recent investigation, but an overall progression of 22% according to RECIST criteria in the liver was observed.
  • Due to the excellent tolerance we increased the daily dose to 30 mg (21/28) and 6 months later a slight regression in the lung and overall stable disease in the liver was observed.

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  • (PMID = 27963457.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Agulnik M, Okuno SH, Von Mehren M, Jovanovic B, Brockstein B, Benjamin RS, Evens AM: An open-label multicenter phase II study of bevacizumab for the treatment of angiosarcoma. J Clin Oncol; 2009 May 20;27(15_suppl):10522

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The study was a two-stage design in which patients with newly diagnosed or relapsed/refractory AS and epithelioid hemangioendotheliomas were treated with bevacizumab 15 mg/kg IV every 3 weeks.
  • Further studies with bevacizumab in combination with chemotherapy should be explored in this disease.

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  • (PMID = 27963911.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Houtappel M, Leguit RJ, Sigurdsson V: [A man with epitheloid hemangioendothelioma. The suspicion of a vascular tumor often occurs late]. Ned Tijdschr Geneeskd; 2010;154:A1131
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  • [Title] [A man with epitheloid hemangioendothelioma. The suspicion of a vascular tumor often occurs late].
  • [Transliterated title] Een man met een epitheloïd hemangio-endothelioom. Het vermoeden van een wekedelentumor ontstaat vaak pas laat.
  • Excision revealed an epithelioid hemangioendothelioma, a rare and malignant vascular tumour, characterized by slow progression and often located on the upper and lower extremities.
  • The patient was referred to a specialist group for soft-tissue tumours.
  • Invasive investigation of a soft-tissue tumour, such as skin biopsy or diagnostic excision, may interfere with potential MRI - the diagnostic imaging tool indicated in the guidelines.
  • However, a soft-tissue tumour is often only suspected at the last moment.
  • When a soft-tissue tumour is suspected, the doctor should refer the patient to one of the specialist groups for soft-tissue tumours for further diagnosis and therapy.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Vascular Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 20456792.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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19. Aissa I, Khaldi H, Yacoub Z, Ayadi-Kadour A, El Mezni F, Capron F, Ghedira H: [Epithelioid hemangioendothelioma mimicking hypersensitivity pneumonitis]. Rev Pneumol Clin; 2008 Aug;64(4):173-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Epithelioid hemangioendothelioma mimicking hypersensitivity pneumonitis].
  • Epithelioid haemangioendothelioma is a rare vascular tumour of slow growth and unfavourable outcome.
  • The diagnosis of the pulmonary localisation is difficult and can mimic by clinical and radiological features other diagnosis as hypersensitivity pneumonitis.
  • Surgical lung biopsy with immunochemistry study concluded to pulmonary epithelioid haemangioendothelioma.
  • Epithelioid haemangioendothelioma is a tumour of intermediate malignancy, of which pulmonary localisation has a nonspecific clinical presentation mimicking diffuse infiltrating pneumonitis.
  • Diagnosis is essentially made by surgical lung biopsy with pathological and immunohistochemical study.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis
  • [MeSH-minor] Adult. Alveolitis, Extrinsic Allergic / diagnosis. Biopsy. Diagnosis, Differential. Humans. Immunohistochemistry. Lung / pathology. Male

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  • (PMID = 19019284.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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20. Pai KR, Thonse VR, Azadeh B, Page RD: Ectopic thymoma of the chest wall. Interact Cardiovasc Thorac Surg; 2005 Feb;4(1):9-11

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  • A chest wall tumour involving the third and fourth ribs and extending extrapleurally and subpectorally was resected following a histopathological diagnosis of hemangioendothelioma obtained at initial incision biopsy.
  • No primary thymic tumour was present in the anterior mediastinum so we conclude that the tumour originated in ectopic thymic tissue.

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  • (PMID = 17670343.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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21. García-Arpa M, Rodríguez-Vázquez M, Cortina P, Delgado M, Vera E, Romero G: [Cutaneous epithelioid hemangioendothelioma]. Actas Dermosifiliogr; 2005 Jul-Aug;96(6):386-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cutaneous epithelioid hemangioendothelioma].
  • [Transliterated title] Hemangioendotelioma epitelioide cutáneo.
  • Epithelioid hemangioendothelioma is a rare vascular tumor of intermediate aggressiveness, which usually appears in adults.
  • It generally affects soft tissues and, less frequently, the lungs and liver.
  • Diagnosis is by histological evaluation, and the epithelioid appearance of the neoplastic endothelial cells is typical, as is the tendency to form vascular channels.
  • We describe the case of a male patient with plantar epithelioid hemangioendothelioma, and we review the literature.
  • [MeSH-major] Foot Diseases / pathology. Hemangioendothelioma, Epithelioid / pathology. Skin Neoplasms / pathology

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  • (PMID = 16476260.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 26
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22. Oliveira A, Carvalho L: [Epithelioid haemangioendothelioma of the pleura: 29 months survival]. Rev Port Pneumol; 2006 Jul-Aug;12(4):455-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Epithelioid haemangioendothelioma of the pleura: 29 months survival].
  • [Transliterated title] Hemangioendotelioma epitelióide da pleura: Sobrevida de 29 meses.
  • Epithelioid haemangioendothelioma of the pleura is a rare neoplasia with a very poor prognosis due to aggressive involvement of the pleura and incomplete surgical treatment.
  • Histological diagnosis and imagiology is also controversial, related to discrete development of the lesions that later reveal nodules.
  • In 2005 there were 31 cases of vascular tumours described in the pleura.
  • Eleven were epithelioid haemangioendotheliomas.
  • This is another case, a 52 year old woman who suffered a traumatism and died 29 months after the histological diagnosis because CAT revealed discrete pleural involvement and a 2 cm nodule was seen only one month before death.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / pathology. Pleural Neoplasms / pathology

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  • (PMID = 16969574.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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23. Tayeb T, Bouzaiene M: [Epithelioid hemangioendothelioma mimicking an occipital artery aneurysm]. Rev Stomatol Chir Maxillofac; 2007 Nov;108(5):451-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Epithelioid hemangioendothelioma mimicking an occipital artery aneurysm].
  • INTRODUCTION: Epithelioid hemangioendothelioma (EHE) is a unique tumor of soft tissues, primarily occurring in adults.
  • Its clinical course being close to that of hemangioma and conventional angiosarcoma, the term epithelioid hemangioendothelioma was suggested.
  • CASE REPORT: The authors report the case of 29-year-old women complaining of a right occipital nodule of the scalp, diagnosed later as an epithelioid hemangioendothelioma located in the scalp and appearing like an aneurysm of the occipital artery on clinical examination and on radiological investigations.
  • Finally it was the histological examination which confirmed the diagnosis of epithelioid hemangioendothelioma.
  • Epithelioid hemangioendotheliomas belong to the epithelioid vascular tumor spectrum.
  • They have in common the morphologic epithelioid aspect of endothelial tumor cells.
  • [MeSH-major] Aneurysm / diagnosis. Head and Neck Neoplasms / diagnosis. Hemangioendothelioma, Epithelioid / diagnosis. Scalp / blood supply. Scalp / pathology
  • [MeSH-minor] Adult. Arteries. Diagnosis, Differential. Female. Humans. Occipital Bone

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  • (PMID = 17916371.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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24. Coulibaly B, Tasei AM, Payan-Defais MJ, Bouvier C, Trousse D, Doddoli C, Figarella-Branger D: [Pulmonary epithelioid haemangioendothelioma: two different clinical courses]. Rev Mal Respir; 2008 Sep;25(7):867-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pulmonary epithelioid haemangioendothelioma: two different clinical courses].
  • In both cases, chest radiography and thoracic CT scans showed multiple, bilateral pulmonary nodules, bronchial endoscopy was normal and surgical biopsy revealed epithelioid haemangioendothelioma.
  • It is a rare primary pulmonary tumour which is usually found in soft tissue, bone or liver.
  • Epithelioid haemangioendothelioma is a vascular tumour usually affecting women less than 40 years of age.
  • Epithelioid haemangioendothelioma is considered a sarcoma without precise histological prognostic criteria.
  • [MeSH-major] Hemangioendothelioma, Epithelioid. Lung Neoplasms

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  • (PMID = 18946414.001).
  • [ISSN] 0761-8425
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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25. Maseda E, Blanco R, Ablanedo A, Iglesias E: [Oropharyngeal kaposiform hemangioendothelioma]. Acta Otorrinolaringol Esp; 2008 Apr;59(4):198-9
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  • [Title] [Oropharyngeal kaposiform hemangioendothelioma].
  • [Transliterated title] Hemangioendotelioma kaposiforme de orofaringe.
  • The kaposiform hemangioendothelioma is a very infrequent tumor proceeding from the endothelial-derived spindle cells, more often found on the limbs, although peritoneal, retroperitoneal and sacrum locations are also prevailing.
  • The kaposiform hemangioendothelioma is almost exclusively found in children and early adolescents, and it is highly associated with the Kasabach-Merritt syndrome and lymphangiomatosis.
  • We report an isolated oropharyngeal kaposiform hemangioendothelioma 9-10-year old male case.
  • [MeSH-major] Hemangioendothelioma / pathology. Oropharyngeal Neoplasms / pathology. Tonsillar Neoplasms / pathology. Xeroderma Pigmentosum / pathology
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Male

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  • (PMID = 18447980.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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26. Charfi L, Mrad K, Karray S, Sassi S, Driss M, Abbes I, Ben Romdhane K: [Epithelioid hemangioendothelioma of bone complicated by femoral fracture]. Rev Chir Orthop Reparatrice Appar Mot; 2005 Dec;91(8):788-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Epithelioid hemangioendothelioma of bone complicated by femoral fracture].
  • Bone hemangioendothelioma can simulate metastasis and must be distinguished by immunohistochemistry.
  • [MeSH-major] Femoral Fractures / etiology. Femoral Neoplasms / complications. Hemangioendothelioma, Epithelioid / complications

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  • (PMID = 16553002.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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27. Tonglet M, Delfosse V, Detry O, De Roover A, Scagnol I, Delhougne B, Brixko C, Dresse D, Fridman V, Lismonde JL, Meurisse M, Honoré P: [Clinical case of the month. Liver transplantation for hepatic epithelioid hemangioendothelioma]. Rev Med Liege; 2009 Feb;64(2):68-70
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  • [Title] [Clinical case of the month. Liver transplantation for hepatic epithelioid hemangioendothelioma].
  • The epithelioid hemangioendothelioma is a rare malignant vascular lesion that may occur within the liver.
  • In this case report, the authors describe the diagnosis and the management of a 52-year-old woman who was diagnosed with hepatic epithelioid hemangioendothelioma and who underwent successful liver transplantation.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / surgery. Liver Neoplasms / surgery


28. García-Marin A, Martín-Gil J, Nofuentes-Riera C, Vaquero-Rodríguez A, Sanz-Sánchez M, Turégano-Fuentes F: [Local resection and radiofrequency hepatic epithelioid hemangioendothelioma]. Rev Gastroenterol Mex; 2010;75(3):335-8
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  • [Title] [Local resection and radiofrequency hepatic epithelioid hemangioendothelioma].
  • [Transliterated title] Resección local y radiofrecuencia en hemangioendotelioma epitelioide hepático.
  • Epithelioid hemangioendothelioma is an uncommon tumor of vascular endothelial cell origin with a clinical course between hemangioma and angiosarcoma.
  • Clinical manifestations and radiological findings are nonspecific, and histopathologic examination is required to establish a definitive diagnosis.
  • [MeSH-major] Catheter Ablation / methods. Hemangioendothelioma, Epithelioid / surgery. Liver Neoplasms / surgery

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  • (PMID = 20959187.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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29. Einsfelder B, Kuhnen C: [Epithelioid hemangioendothelioma of the lung (IVBAT)--clinicopathological and immunohistochemical analysis of 11 cases]. Pathologe; 2006 Mar;27(2):106-15
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  • [Title] [Epithelioid hemangioendothelioma of the lung (IVBAT)--clinicopathological and immunohistochemical analysis of 11 cases].
  • Epithelioid hemangioendothelioma (EHE) of the lungs (syn.: intravascular bronchioloalveolar tumor/IVBAT) is a neoplasm with a vascular line of differentiation.
  • All tumors were characterized by epithelioid tumor cells with nests, cords and strands embedded in a sclerosing, hyaline matrix with alveolar, bronchiolar and vascular extension.
  • Follow-up was available for 8 patients with a range of 6 to 105 months (mean: 51.5 months, median: 52 months): 3 patients died (2 certainly from their tumors), 4 are alive disease-free, and one is alive with metastases.
  • EHE of the lungs (IVBAT) represents an intermediate-grade, malignant, mesenchymal neoplasm with a characteristic histological appearance and immunohistochemical profile.
  • [MeSH-major] Biomarkers, Tumor / analysis. Hemangioendothelioma, Epithelioid / pathology. Lung Neoplasms / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Cell Transformation, Neoplastic / pathology. Endothelium, Vascular / pathology. Female. Humans. Lung / pathology. Male. Middle Aged. Mitotic Index. Necrosis. Neoplasm Invasiveness. Ossification, Heterotopic / diagnosis. Ossification, Heterotopic / pathology. Prognosis. Pulmonary Veins / pathology. Survival Analysis

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  • (PMID = 16421704.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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30. Messias P, Bernardo J, Antunes MJ: Primary left atrial haemangioendothelioma. Interact Cardiovasc Thorac Surg; 2008 Oct;7(5):945-6
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  • [Title] Primary left atrial haemangioendothelioma.
  • We describe the case of a 21-year-old female patient with epithelioid haemangioendothelioma of the roof of the left atrium.
  • The patient underwent radical resection of the tumour with large disease-free margins, which required reconstruction of left and right atrial superior walls.
  • There is no single treatment that can be prescribed but, because of their biologic behaviour, epithelioid haemangioendotheliomas must be regarded as fully malignant neoplasms and ought to be resected radically to prevent metastatic disease, and to improve life expectancy and quality of life.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Neoplasms / surgery. Hemangioendothelioma, Epithelioid / surgery

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  • (PMID = 18635584.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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31. Botnaru V, Munteanu O, Vataman V, Saptefraţi L: [Pulmonary epithelioid hemangioendothelioma--a case report]. Pneumologia; 2008 Oct-Dec;57(4):234-5, 237-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pulmonary epithelioid hemangioendothelioma--a case report].
  • [Transliterated title] Hemangioendoteliom epitelioid pulmonar --prezentare de caz.
  • Pulmonary epithelioid hemangioendothelioma (PEH) is a rare soft tissue tumor of endothelial origin that occurs among young women and typically presents as bilateral multiple nodules, readily mistaken for carcinoma or, as in this case, Wegener's granulomatosis.
  • This is a rare disease, with approximately 50 cases described in the literature.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Hemangioendothelioma, Epithelioid / surgery. Lung Neoplasms / diagnosis. Lung Neoplasms / surgery
  • [MeSH-minor] Adult. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Granulomatosis with Polyangiitis / diagnosis. Humans. Rare Diseases. Tomography, X-Ray Computed

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  • (PMID = 19186686.001).
  • [ISSN] 2067-2993
  • [Journal-full-title] Pneumologia (Bucharest, Romania)
  • [ISO-abbreviation] Pneumologia
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor
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32. Maisonnette F, Hardemann S, Abita T, Durand-Fontanier S, Valleix D, Descottes B: [Hepatic haemangioendothelioma: case report and review of literature]. Ann Chir; 2006 Feb;131(2):115-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hepatic haemangioendothelioma: case report and review of literature].
  • After reexamination of histology we discovered hepatic haemangioendothelioma.
  • The patient died 18 month after diagnosis although chemotherapy.
  • [MeSH-major] Hemangioendothelioma. Liver Neoplasms

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  • (PMID = 16246294.001).
  • [ISSN] 0003-3944
  • [Journal-full-title] Annales de chirurgie
  • [ISO-abbreviation] Ann Chir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 11
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33. Ponferrada A, Salcedo M, Matilla A, Núñez O, Bañares R, Alvarez E, Clemente G: [Clinical heterogeneity and distinct outcomes in hepatic epithelioid hemangioendothelioma]. Gastroenterol Hepatol; 2005 Jun-Jul;28(6):321-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical heterogeneity and distinct outcomes in hepatic epithelioid hemangioendothelioma].
  • [Transliterated title] Heterogeneidad clínica y evolutiva del hemangioendotelioma epitelioide hepático.
  • Epithelioid hemangioendothelioma is an infrequent mesenchymal tumor of unknown etiology and variable clinical symptoms.
  • Diagnosis is difficult and detailed pathological analysis is required.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Bone Neoplasms / secondary. Disease Progression. Fatal Outcome. Female. Hepatitis B / complications. Hepatitis C, Chronic / complications. Humans. Incidental Findings. Leiomyoma. Liver Transplantation. Lung Neoplasms / radiography. Lung Neoplasms / secondary. Middle Aged. Neoplasms, Second Primary. Pregnancy. Puerperal Disorders / pathology. Treatment Outcome. Uterine Neoplasms

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  • (PMID = 15989812.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 36
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34. Tejera-Vaquerizo A, Herrera-Ceballos E, Bosch-García R, Fernandez-Orland A, Matilla A: Composite cutaneous hemangioendothelioma on the back. Am J Dermatopathol; 2008 Jun;30(3):262-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Composite cutaneous hemangioendothelioma on the back.
  • Composite cutaneous hemangioendothelioma (HE) is the most recently described variant of the lesions known as HEs.
  • This neoplasm is considered to be of borderline or low-grade malignancy, because despite its frequency it rarely metastasizes.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD31 / analysis. Back. Biomarkers, Tumor / analysis. Epithelioid Cells / chemistry. Epithelioid Cells / pathology. Female. Humans. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Treatment Outcome

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  • (PMID = 18496428.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Biomarkers, Tumor
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35. Sun ZJ, Zhang L, Zhang WF, Chen XM, Lai FM, Zhao YF: Epithelioid hemangioendothelioma of the oral cavity. Oral Dis; 2007 Mar;13(2):244-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid hemangioendothelioma of the oral cavity.
  • OBJECTIVE: To investigate the clinicopathological characteristics and biologic behaviour of epithelioid hemangioendothelioma in the oral cavity.
  • MATERIALS AND METHODS: The clinical features and pathological findings of nine cases with intraoral epithelioid hemangioendothelioma were reviewed, including immunohistochemistry study.
  • CONCLUSIONS: Wide local excision with long-term follow-up seems to be the treatment of choice for intraoral epithelioid hemangioendothelioma because of their unpredictable biological behaviour and recurrence potential.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Antigens, CD34 / analysis. Child. Female. Gingival Neoplasms / pathology. Herpesvirus 8, Human / isolation & purification. Humans. Keratins / analysis. Lip Neoplasms / pathology. Male. Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Middle Aged. Mouth Floor / pathology. Mouth Mucosa / pathology. Mucin-1 / analysis. Neoplasm Recurrence, Local / pathology. Retrospective Studies. S100 Proteins / analysis. Tongue Neoplasms / pathology. Vimentin / analysis. von Willebrand Factor / analysis

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  • (PMID = 17305630.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Mucin-1; 0 / S100 Proteins; 0 / Vimentin; 0 / von Willebrand Factor; 68238-35-7 / Keratins
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36. Hannachi Sassi S, Mansouri D, Abbes I, Dhouib R, Driss M, Mrad K, Ben Ayed F, Ben Romdhane K: [Soft tissue epithelioid hemangioendothelioma: a case report]. Rev Chir Orthop Reparatrice Appar Mot; 2005 Nov;91(7):671-5
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  • [Title] [Soft tissue epithelioid hemangioendothelioma: a case report].
  • We report a case of epithelioid hemangioendothelioma observed in soft tissue in a 35-year-old man who presented a painful mass of the right arm which progressed in size for two years.
  • Histological and immunohistochemical examination led to the diagnosis of soft tissue epithelioid hemangioendothelioma.
  • [MeSH-major] Hemangioendothelioma, Epithelioid. Soft Tissue Neoplasms

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  • (PMID = 16327673.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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37. Bruegel M, Waldt S, Weirich G, Woertler K, Rummeny EJ: Multifocal epithelioid hemangioendothelioma of the phalanges of the hand. Skeletal Radiol; 2006 Oct;35(10):787-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multifocal epithelioid hemangioendothelioma of the phalanges of the hand.
  • Epithelioid hemangioendothelioma (EH) of bone is a rare vascular neoplasm characterized by epithelioid endothelial cells and a variable biologic behaviour.
  • Approximately half of the cases present with multifocal disease.
  • The latter feature can be helpful in suggesting the diagnosis of a vascular tumor; on the other hand, it strengthens the need for a skeletal survey or whole-body MRI/CT.
  • We report on the clinical, histologic and radiologic features-including CT and MRI findings-of EH in a case of multifocal disease of the phalanges of the hand, a very uncommon anatomic site of affliction.
  • [MeSH-major] Bone Neoplasms / diagnosis. Finger Phalanges / pathology. Hemangioendothelioma, Epithelioid / diagnosis

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  • [Cites] Skeletal Radiol. 1996 May;25(4):391-5 [8738008.001]
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  • (PMID = 16132980.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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38. Ouadnouni Y, Bouchikh M, Achir A, Zouaidia F, Smahi M, Msougar Y, Lakranbi M, Afqir S, Mahassini N, Benosman A: Pulmonary epithelioid hemangioendothelioma: a case report. Cases J; 2009;2:8235

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary epithelioid hemangioendothelioma: a case report.
  • INTRODUCTION: The pulmonary epithelioid hemangioendothelioma is a rare vascular intermediate malignancy tumour.
  • The histologic examination with immunomarking led to an epithelioid hemangioendothelioma.
  • CONCLUSIONS: The pulmonary epithelioid hemangioendothelioma is a tumour of unpredictable prognosis, bad when linked to the plurifocal and symptomatic forms.

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  • [Cites] Ann Thorac Surg. 2006 Dec;82(6):2010-3 [17126100.001]
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  • (PMID = 19918408.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769418
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39. Safirstein J, Aksenov S, Smith F: Cardiac epithelioid hemangioendothelioma with 8-year follow-up. Cardiovasc Pathol; 2007 May-Jun;16(3):183-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac epithelioid hemangioendothelioma with 8-year follow-up.
  • An incidentally discovered right atrial mass excised from the heart of a 51-year-old woman was found on pathological examination to be an epithelioid hemangioendothelioma.
  • To our knowledge, this is the first report on the behavior of this distinctive vascular neoplasm occurring as an isolated cardiac tumor.
  • [MeSH-major] Heart Neoplasms / pathology. Hemangioendothelioma, Epithelioid / pathology
  • [MeSH-minor] Disease-Free Survival. Echocardiography. Female. Follow-Up Studies. Heart Atria / pathology. Heart Atria / surgery. Heart Atria / ultrasonography. Humans. Middle Aged

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  • (PMID = 17502249.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Askri A, Mannai S, Landolsi S, Ben Farhat L, Said W, Dali N, Khalfallah MT, Hendaoui L: [Hepatic epithelioid hemangioendothelioma: review of 3 cases]. J Radiol; 2009 Mar;90(3 Pt 1):310-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hepatic epithelioid hemangioendothelioma: review of 3 cases].
  • Hepatic epithelioid hemangioendothelioma (EHE) is a rare neoplasm of vascular origin.
  • Involvement often is multinodular simulating metastases from a primatry extra-hepatic malignancy leading to delays in diagnosis.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Liver Neoplasms / diagnosis

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  • (PMID = 19421116.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
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41. da Silva BB, Lopes-Costa PV, Furtado-Veloso AM, Borges RS: Vulvar epithelioid hemangioendothelioma. Gynecol Oncol; 2007 May;105(2):539-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vulvar epithelioid hemangioendothelioma.
  • BACKGROUND: Epithelioid hemangioendothelioma (EH) is a rare vascular tumor whose localization in the vulva is extremely rare.
  • Following confirmation of the diagnosis of epithelioid hemangioendothelioma, the only treatment consisted of hemivulvectomy and right inguinal lymphadenectomy.
  • There is no sign of recurrence of the disease.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / pathology. Hemangioendothelioma, Epithelioid / surgery. Vulvar Neoplasms / pathology

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  • (PMID = 17306346.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Veening MA, Verbeke JI, Witbreuk MM, Kaspers GJ: Kaposiform (spindle cell) hemangioendotelioma in a child with an unusual presentation. J Pediatr Hematol Oncol; 2010 Apr;32(3):240-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kaposiform (spindle cell) hemangioendotelioma in a child with an unusual presentation.
  • We describe a male child with multifocal kaposiform hemangioendothelioma in the right and left cervical region with development of Kasabach-Merritt syndrome.
  • The question remains whether the multiple osteolytic bone lesions also reflect kaposiform hemangioendothelioma localization.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Neoplasm Recurrence, Local / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 20387265.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Interferon-alpha; 0 / Recombinant Proteins; 76543-88-9 / interferon alfa-2a
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43. Suga K, Kawakami Y, Hiyama A, Hori K: F-18 FDG PET/CT monitoring of radiation therapeutic effect in hepatic epithelioid hemangioendothelioma. Clin Nucl Med; 2009 Mar;34(3):199-202
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] F-18 FDG PET/CT monitoring of radiation therapeutic effect in hepatic epithelioid hemangioendothelioma.
  • We report the F-18 FDG PET/CT findings in a 59-year-old man with a rare hepatic tumor of malignant epithelioid hemangioendothelioma, who was treated with radiotherapy (RT).
  • RT is one of the options for treatment of hepatic epithelioid hemangioendothelioma.
  • F-18 FDG PET/computed tomography appears to be useful for monitoring the effect of RT in this neoplasm.
  • [MeSH-major] Fluorodeoxyglucose F18. Hemangioendothelioma, Epithelioid / diagnosis. Hemangioendothelioma, Epithelioid / radiotherapy. Liver Neoplasms / diagnosis. Liver Neoplasms / radiotherapy

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  • (PMID = 19352294.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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44. Blatt J, Stavas J, Moats-Staats B, Woosley J, Morrell DS: Treatment of childhood kaposiform hemangioendothelioma with sirolimus. Pediatr Blood Cancer; 2010 Dec 15;55(7):1396-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of childhood kaposiform hemangioendothelioma with sirolimus.
  • Limited experience suggests that it may have application to the treatment of vascular lesions.
  • We describe our experience with a 1-year-old female with a kaposiform hemangioendothelioma and Kasabach-Merritt phenomenon who had rapid and dramatic response to sirolimus (0.1 mg/kg/day).
  • This case provides further rationale for clinical trials of sirolimus in the treatment of vascular lesions.
  • [MeSH-major] Angiogenesis Inhibitors / therapeutic use. Antibiotics, Antineoplastic / therapeutic use. Hemangioendothelioma / drug therapy. Sirolimus / therapeutic use. Skin Neoplasms / drug therapy


45. Zahir ST, Benrazavi SS, Binesh F: Kaposiform hemangioendothelioma: report of a case unresponsive to usual medical treatments. J Res Med Sci; 2009 Nov;14(6):389-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kaposiform hemangioendothelioma: report of a case unresponsive to usual medical treatments.
  • Kaposiform hemangioendothelioma is an aggressive endothelial-derived spindle cell neoplasm that occurs nearly exclusively during childhood and teenage years.
  • Despite hospitalization in intensive care unit (ICU) and transfusion of platelets and packed red blood cells as well as medical managements such as oral prednisolone, intravenous (IV) methylprednisolone and interferon alpha, thrombocytopenia persisted, so surgical resection was considered.
  • The histopathological findings were distinctive and characteristic of kaposiform hemangioendothelioma.

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  • [Cites] Int J Dermatol. 2003 Sep;42(9):741-8 [12956695.001]
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  • (PMID = 21772913.001).
  • [ISSN] 1735-7136
  • [Journal-full-title] Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
  • [ISO-abbreviation] J Res Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Other-IDs] NLM/ PMC3129083
  • [Keywords] NOTNLM ; Arm / Hemangioendothelioma / Infant-Newborn / Sarcoma-Kaposi / Surgery
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46. Park MS, Ravi V, Araujo DM: Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor. Curr Opin Oncol; 2010 Jul;22(4):351-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor.
  • PURPOSE OF REVIEW: This review highlights the current body of knowledge regarding the role of the vascular endothelial growth factor (VEGF) and its receptor (VEGFR) in angiosarcoma, epithelioid hemangioendothelioma (EHE), and hemangiopericytoma/solitary fibrous tumor (HPC/SFT).
  • RECENT FINDINGS: Several phase II trials in advanced soft tissue sarcoma patients have investigated the efficacy of bevacizumab, an anti-VEGF antibody, as well as sunitinib, sorafenib, and pazopanib, VEGFR tyrosine kinase inhibitors (TKIs).
  • Although response rates and progression-free survival periods were generally low, several angiosarcoma, EHE, and HPC/SFT patients demonstrated response or durable disease stabilization on these therapies.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / physiopathology. Hemangiosarcoma / physiopathology. Receptors, Vascular Endothelial Growth Factor / physiology. Signal Transduction / physiology. Solitary Fibrous Tumors / physiopathology. Vascular Endothelial Growth Factor A / physiology

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  • (PMID = 20485168.001).
  • [ISSN] 1531-703X
  • [Journal-full-title] Current opinion in oncology
  • [ISO-abbreviation] Curr Opin Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Vascular Endothelial Growth Factor A; EC 2.7.10.1 / Receptors, Vascular Endothelial Growth Factor
  • [Number-of-references] 58
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47. Alomari AI: The lollipop sign: a new cross-sectional sign of hepatic epithelioid hemangioendothelioma. Eur J Radiol; 2006 Sep;59(3):460-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The lollipop sign: a new cross-sectional sign of hepatic epithelioid hemangioendothelioma.
  • In four cases of hepatic epithelioid hemangioendothelioma (HEHE), multiple liver lesions were depicted on enhanced computed tomography (CT) and/or magnetic resonance imaging (MRI) scans.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 16644166.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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48. Bienaimé A, Rojat-Habib MC, Hesse S, Pelissier JF, Bonerandi JJ: [Giant vascular tumour in an adult: tufted angioma or kaposiform hemangioendothelioma]. Ann Dermatol Venereol; 2006 Jun-Jul;133(6-7):553-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant vascular tumour in an adult: tufted angioma or kaposiform hemangioendothelioma].
  • INTRODUCTION: Tufted angioma and kaposiform hemangioendothelioma are two rare benign but aggressive vascular tumours that occur mainly in children.
  • OBSERVATION: A 72 year-old man consulted for a 50 cm wide vascular tumour of the right shoulder which was increasing for 10 years.
  • On histological examination there were features of tufted angioma and kaposiform hemangioendothelioma.
  • The histological association of aspects which could correspond to tufted angioma and kaposiform hemangioendothelioma seems to confirm recent publications which support the hypothesis that these two tumours are two evolutive stages of one and only entity.
  • [MeSH-major] Hemangioendothelioma / pathology. Hemangioma / pathology. Skin Neoplasms / pathology


49. Mansour Z, Neuville A, Massard G: Mediastinal epithelioid haemangioendothelioma: a rare mediastinal tumour. Interact Cardiovasc Thorac Surg; 2010 Jan;10(1):122-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mediastinal epithelioid haemangioendothelioma: a rare mediastinal tumour.
  • We report the case of a 35-year-old patient with an incidental finding of an asymptomatic large (9.5 cm in diameter) anterior mediastinal tumour.
  • Radiological findings favoured the diagnosis of a benign mediastinal teratoma.
  • Immunohistochemistry diagnosed a mediastinal 'epithelioid haemangioendothelioma', which is a tumour of vascular origin.
  • We present the case of this patient with the iconography, along with a review of the available literature concerning mediastinal epithelioid haemangioendotheliomas.
  • [MeSH-major] Brachiocephalic Veins / pathology. Hemangioendothelioma, Epithelioid / pathology. Mediastinal Neoplasms / pathology. Vascular Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnostic Errors. Humans. Immunohistochemistry. Incidental Findings. Male. Neoplasm Invasiveness. Sternotomy. Teratoma / diagnosis. Tomography, X-Ray Computed. Treatment Outcome. Vascular Surgical Procedures

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  • (PMID = 19833641.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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50. Langrehr JM, Petersen I, Pfitzmann R, Lopez-Hänninen E: [Malignant epithelioid hemangioendothelioma of the liver. Results of surgical treatment strategies]. Chirurg; 2005 Dec;76(12):1161-7
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  • [Title] [Malignant epithelioid hemangioendothelioma of the liver. Results of surgical treatment strategies].
  • BACKGROUND: Malignant epithelioid hemangioendothelioma is a rare vascular tumor described mostly in soft tissue, lungs, or liver.
  • MATERIAL AND METHODS: During a period of 5 years, seven patients with the histological diagnosis of hepatic epithelia hemangioendothelioma were seen.
  • The therapeutic measures and course of disease are given as case reports.
  • CONCLUSION: Anatomic liver resection, or in the case of diffuse tumor spread, orthotopic liver transplantation, show favorable long-term results for the treatment of hepatic epithelioid hemangioendothelioma.
  • [MeSH-major] Hemangioendothelioma / surgery. Hepatectomy. Liver Neoplasms / surgery. Liver Transplantation
  • [MeSH-minor] Adult. Aged. Disease-Free Survival. Follow-Up Studies. Humans. Liver / pathology. Middle Aged. Prospective Studies. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16096736.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Germany
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51. Emamaullee JA, Edgar R, Toso C, Thiesen A, Bain V, Bigam D, Kneteman N, Shapiro AM: Vascular endothelial growth factor expression in hepatic epithelioid hemangioendothelioma: Implications for treatment and surgical management. Liver Transpl; 2010 Feb;16(2):191-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vascular endothelial growth factor expression in hepatic epithelioid hemangioendothelioma: Implications for treatment and surgical management.
  • Epithelioid hemangioendothelioma (EHE) is a low-grade, malignant vascular tumor that most commonly presents within the liver.
  • Patients with hepatic EHE are often candidates for liver transplantation as the disease is usually multifocal at diagnosis.
  • Although these patients achieve excellent early outcomes post-transplant, there are very few data regarding tumor markers that can further direct chemotherapy in hepatic EHE to prevent recurrent disease.
  • The purpose of this study was to analyze the expression of the angiogenic factor vascular endothelial growth factor (VEGF) and its receptors in hepatic EHE.
  • These data suggest that anti-VEGF chemotherapeutic agents will be of use in patients with hepatic EHE, particularly as a means of reducing the tumor volume prior to resection, as a means of treating unresectable or metastatic disease, or as an adjuvant therapy in the setting of liver transplantation.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / metabolism. Hemangioendothelioma, Epithelioid / surgery. Liver Neoplasms / metabolism. Liver Neoplasms / surgery. Liver Transplantation. Vascular Endothelial Growth Factor A / metabolism
  • [MeSH-minor] Adolescent. Adult. Angiogenesis Inhibitors / therapeutic use. Biomarkers, Tumor / metabolism. Biopsy. Disease-Free Survival. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Recurrence, Local / metabolism. Neoplasm Recurrence, Local / pathology. Neovascularization, Pathologic / drug therapy. Neovascularization, Pathologic / metabolism. Neovascularization, Pathologic / pathology. Retrospective Studies. Vascular Endothelial Growth Factor Receptor-1 / metabolism. Vascular Endothelial Growth Factor Receptor-2 / metabolism

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  • (PMID = 20104492.001).
  • [ISSN] 1527-6473
  • [Journal-full-title] Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • [ISO-abbreviation] Liver Transpl.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Biomarkers, Tumor; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; EC 2.7.10.1 / FLT1 protein, human; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-1; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2
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52. Madhusudhan KS, Srivastava DN, Gamanagatti S: Multifocal epithelioid hemangioendothelioma presenting with hemoptysis. Indian J Pediatr; 2010 Jun;77(6):699-700
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  • [Title] Multifocal epithelioid hemangioendothelioma presenting with hemoptysis.
  • We present a case of multifocal epithelioid hemangioendothelioma occurring in an adolescent boy who presented with massive hemoptysis and showed a pulmonary perihilar mass with multiple lesions in the liver and two lytic lesions in the ribs on imaging.
  • The diagnosis was confirmed by lung and liver biopsy.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hemangioendothelioma, Epithelioid / diagnosis. Hemoptysis / etiology. Liver Neoplasms / diagnosis. Lung Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis
  • [MeSH-minor] Biopsy. Child. Diagnosis, Differential. Glucocorticoids / administration & dosage. Glucocorticoids / therapeutic use. Humans. Male. Ribs / pathology. Treatment Outcome

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  • [Cites] Cancer. 2006 Nov 1;107(9):2108-21 [17019735.001]
  • [Cites] J Comput Assist Tomogr. 2000 Sep-Oct;24(5):719-20 [11045691.001]
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  • (PMID = 20532691.001).
  • [ISSN] 0973-7693
  • [Journal-full-title] Indian journal of pediatrics
  • [ISO-abbreviation] Indian J Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Glucocorticoids
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53. van der Meijs BB, Merks JH, de Haan TR, Tabbers MM, van Rijn RR: Neonatal hepatic haemangioendothelioma: treatment options and dilemmas. Pediatr Radiol; 2009 Mar;39(3):277-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neonatal hepatic haemangioendothelioma: treatment options and dilemmas.
  • We describe a case of rapidly progressive neonatal diffuse hepatic haemangioendotheliomas.
  • The clinical picture was characterized by respiratory insufficiency due to gross abdominal enlargement, coagulopathy, and the development of cardiovascular insufficiency during the course of disease.
  • Unfortunately, the child died as a consequence of the disease.
  • As cases like this are rare and are associated with severe morbidity and high mortality, more knowledge needs to be gained on infantile hepatic haemangioendotheliomas and their optimal treatment.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Hemangioendothelioma / therapy. Liver Neoplasms / diagnosis. Liver Neoplasms / therapy

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  • [CommentIn] Pediatr Radiol. 2009 Jun;39(6):637-8 [19387632.001]
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  • (PMID = 19083217.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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54. Fernández Y, Bernabeu-Wittel M, García-Morillo JS: Kaposiform hemangioendothelioma. Eur J Intern Med; 2009 Mar;20(2):106-13
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  • [Title] Kaposiform hemangioendothelioma.
  • Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular neoplasm that mainly occurs during childhood.
  • It generally originates on the skin, usually affecting deeper tissue by infiltrative growth.
  • In conclusion, the onset of a consumptive coagulopathy following the presence of a vascular tumor, in children as well as in older patients, should spark suspicion of KHE, among other entities.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Hemangioendothelioma / therapy. Skin Neoplasms / diagnosis. Skin Neoplasms / therapy. Vascular Neoplasms / diagnosis. Vascular Neoplasms / therapy

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  • (PMID = 19327597.001).
  • [ISSN] 1879-0828
  • [Journal-full-title] European journal of internal medicine
  • [ISO-abbreviation] Eur. J. Intern. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 87
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55. Posligua L, Anatelli F, Dehner LP, Pfeifer JD: Primary peritoneal epithelioid hemangioendothelioma. Int J Surg Pathol; 2006 Jul;14(3):257-67
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  • [Title] Primary peritoneal epithelioid hemangioendothelioma.
  • Epithelioid hemangioendothelioma is an uncommon malignant vascular tumor of intermediate grade that occurs in a variety of organs and soft tissues.
  • Diagnosis of epithelioid hemangioendothelioma is often complicated by the rarity of the tumor, and because the tumor shares many morphologic features with other peritoneal neoplasms.
  • This report presents 3 cases of epithelioid hemangioendotheliomas arising as primary tumors of the peritoneum and reviews 7 previously reported cases to establish the demographic, clinical, morphologic, immunohistochemical, and ultrastructural features of this neoplasm.
  • These cases demonstrate that the light microscopic features are very similar to epithelioid hemangioendothelioma arising at more conventional sites, such as the liver, that immunohistochemical analysis provides a reliable approach for confirming or establishing the diagnosis, and that at least one endothelial marker (either CD31, CD34, or factor VIII) should be positive for a definitive diagnosis.
  • This series identifies the characteristics of peritoneal epithelioid hemangioendothelioma that can be reliably used for diagnosis.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / secondary. Peritoneal Neoplasms / pathology

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  • (PMID = 16959716.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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56. Deraedt K, Vander Poorten V, Van Geet C, Renard M, De Wever I, Sciot R: Multifocal kaposiform haemangioendothelioma. Virchows Arch; 2006 Jun;448(6):843-6
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  • [Title] Multifocal kaposiform haemangioendothelioma.
  • Kaposiform haemangioendothelioma (KHE) is a rare, locally aggressive vascular spindle cell proliferation, with resemblance to Kaposi's sarcoma.
  • Histological examination revealed a typical infiltrative multilobular spindle cell proliferation with slit-like vascular spaces in these three localisations.
  • Immunohistochemical stains showed positivity for CD34 and CD31 and many alpha-smooth muscle actin-positive spindle cells around the vascular spaces.
  • [MeSH-major] Hemangioendothelioma / pathology. Sarcoma, Kaposi / pathology. Submandibular Gland / pathology. Submandibular Gland Neoplasms / pathology. Thyroid Gland / pathology. Thyroid Neoplasms / pathology

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  • (PMID = 16596383.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Antigens, CD34; 0 / Biomarkers, Tumor
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57. Chen TT, Lai CT, Wu CL, Wang TY, Shih BF, Hung CL, Kuo LK, Weng YL, Lee SY: Cardiac tamponade caused by epithelioid haemangioendothelioma. BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac tamponade caused by epithelioid haemangioendothelioma.
  • Epithelioid haemangioendothelioma (EHE) is a tumour of vascular endothelial origin.
  • The rarity of EHE has limited the complete understanding of the disease.

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  • (PMID = 21686542.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3027560
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58. Chen YJ, Wang CK, Tien YC, Hsieh TJ: MRI of multifocal kaposiform haemangioendothelioma without Kasabach-Merritt phenomenon. Br J Radiol; 2009 Mar;82(975):e51-4
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  • [Title] MRI of multifocal kaposiform haemangioendothelioma without Kasabach-Merritt phenomenon.
  • Kaposiform haemangioendothelioma is a rare soft-tissue tumour of infants and children, and presents as a moderately aggressive malignancy.
  • We present the MRI findings of a histologically proven case of Kaposiform haemangioendothelioma without Kasabach-Merritt phenomenon or typical skin changes.
  • [MeSH-major] Hemangioendothelioma / pathology. Pain / etiology. Skin / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Biopsy. Child. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Treatment Outcome

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  • (PMID = 19211904.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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59. Goh SG, Calonje E: Cutaneous vascular tumours: an update. Histopathology; 2008 May;52(6):661-73
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  • [Title] Cutaneous vascular tumours: an update.
  • This review evaluates changes in vascular nomenclature particularly in the category of vascular tumours of intermediate malignancy that includes the various haemangioendotheliomas, Kaposi's sarcoma and giant cell angioblastoma.
  • Recently described entities in this category, including the latter tumour and composite haemangioendothelioma, are described.
  • Several newly characterized vascular tumours not included in recent classifications of vascular tumours are also summarized.
  • The newly introduced clinical classification of congenital haemangiomas into non-involuting and rapidly involuting variants and radiation-induced atypical vascular lesions are also reviewed.
  • [MeSH-major] Neoplasms, Vascular Tissue / classification. Neoplasms, Vascular Tissue / pathology. Skin Neoplasms / classification. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Hemangioendothelioma / diagnosis. Hemangioendothelioma / pathology. Hemangioma / diagnosis. Hemangioma / pathology. Humans. Lymphangioma / diagnosis. Lymphangioma / pathology. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / pathology

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  • (PMID = 18266723.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 69
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60. Pareja E, Cortés M, Rayon M, Moya A, Mir J: [Epithelioid hemangioendothelioma: an uncommon liver tumor]. Gastroenterol Hepatol; 2010 Jun-Jul;33(6):445-8
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  • [Title] [Epithelioid hemangioendothelioma: an uncommon liver tumor].
  • [Transliterated title] Hemangioendotelioma epitelioide: un tumor hepatico infrecuente.
  • After biopsy, the patient was diagnosed with epithelioid hemangioendothelioma of the liver.
  • Epithelioid hemangioendothelioma is a rare entity with an unpredictable, potentially fatal, clinical course and outcome.
  • Due to its rarity, this entity should be considered when a solitary hepatic lesion is detected and should be included in the differential diagnosis with liver metastases.
  • We describe the clinical and pathological characteristics of epithelioid hemangioendothelioma of the liver and report a new case of this entity.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Adenoma / diagnosis. Atrophy. Biomarkers, Tumor / analysis. Carcinoma / secondary. Carcinoma, Hepatocellular / diagnosis. Diagnosis, Differential. Dyslipidemias / complications. Female. Humans. Incidental Findings. Kidney / pathology. Kidney / ultrasonography. Middle Aged. Tomography, X-Ray Computed

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  • [Copyright] Copyright 2010 Elsevier España, S.L. All rights reserved.
  • (PMID = 20570012.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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61. Parsons A, Sheehan DJ, Sangueza OP: Retiform hemangioendotheliomas usually do not express D2-40 and VEGFR-3. Am J Dermatopathol; 2008 Feb;30(1):31-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Retiform hemangioendotheliomas usually do not express D2-40 and VEGFR-3.
  • Retiform hemangioendothelioma (RH) is a rare vascular neoplasm most often occurring in the limbs of middle-aged females.
  • This entity is characterized by infiltrative vascular spaces arranged in a pattern similar to the rete testis.
  • This neoplasm frequently recurs but rarely metastasizes.
  • RH tumor cells react with vascular endothelial markers CD31, CD34, and factor VIII-related antigen.
  • We stained 4 RHs with mouse monoclonal antibodies against D2-40 and CD31 and 3 of the 4 RHs with vascular endothelial growth factor receptor 3 (VEGFR-3), to further evaluate whether RH had lymphatic differentiation, in addition to vascular differentiation.
  • Three of the 4 RH biopsies failed to demonstrate D2-40, none expressed VEGFR-3, whereas CD31 was strongly positive, suggesting that RH is a vascular entity which usually does not have lymphatic differentiation, but may rarely express D2-40.
  • [MeSH-major] Biomarkers, Tumor / analysis. Endothelium, Lymphatic / metabolism. Hemangioendothelioma / metabolism. Sialoglycoproteins / biosynthesis. Soft Tissue Neoplasms / metabolism. Vascular Endothelial Growth Factor Receptor-3 / biosynthesis

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  • (PMID = 18212541.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, CD31; 0 / Biomarkers, Tumor; 0 / Sialoglycoproteins; 0 / monoclonal antibody D2-40; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-3
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62. Kalof AN, Cooper K: D2-40 immunohistochemistry--so far! Adv Anat Pathol; 2009 Jan;16(1):62-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Since its introduction, D2-40 immunoexpression has been described in a variety of lymphovascular neoplasms including lymphangioma, Kaposi sarcoma, and hemangioendothelioma, as well as nonvascular neoplasms such as epithelioid mesothelioma, seminoma, and hemangioblastoma.

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  • (PMID = 19098468.001).
  • [ISSN] 1533-4031
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / monoclonal antibody D2-40
  • [Number-of-references] 14
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63. Grossman EJ, Millis JM: Liver transplantation for non-hepatocellular carcinoma malignancy: Indications, limitations, and analysis of the current literature. Liver Transpl; 2010 Aug;16(8):930-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hepatic epithelioid hemangioendothelioma is a rare tumor of vascular origin.
  • [MeSH-minor] Aged. Cholangiocarcinoma / therapy. Hemangioendothelioma / therapy. Hepatoblastoma / therapy. Humans. Immunosuppressive Agents / therapeutic use. Liver / pathology. Medical Oncology / methods. Middle Aged. Neoplasm Metastasis. Neuroendocrine Tumors / therapy. Sarcoma / therapy. Treatment Outcome

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  • [Copyright] (c) 2010 AASLD.
  • (PMID = 20677284.001).
  • [ISSN] 1527-6473
  • [Journal-full-title] Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • [ISO-abbreviation] Liver Transpl.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
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64. Ayadi L, Khabir A: Pediatric angiosarcoma of soft tissue: a rare clinicopathologic entity. Arch Pathol Lab Med; 2010 Mar;134(3):481-5
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  • [Title] Pediatric angiosarcoma of soft tissue: a rare clinicopathologic entity.
  • The differential diagnosis includes Kaposi sarcoma, epithelioid hemangioendothelioma, hemangiopericytoma, and spindle cell hemangioendothelioma whose prognosis is different.
  • Malignant vascular tumors are rare in children in the first 2 decades of life and when they do occur they seem to be more aggressive than in adults.
  • Pathologic diagnosis is difficult particularly in poorly differentiated angiosarcomas requiring immunohistochemical study to confirm vascular differentiation.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Hemangiosarcoma / pathology. Mediastinal Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / analysis. Child. Child, Preschool. Combined Modality Therapy. Diagnosis, Differential. Female. Hemangioendothelioma, Epithelioid / diagnosis. Hemangiopericytoma / diagnosis. Humans. Infant. Male. Prognosis. Sarcoma, Kaposi / diagnosis

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  • (PMID = 20196675.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 17
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65. Sheehan M, Roumpf SO, Summerlin DJ, Billings SD: Spindle cell hemangioma: report of a case presenting in the oral cavity. J Cutan Pathol; 2007 Oct;34(10):797-800
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Spindle cell hemangioma, formerly termed spindle cell hemangioendothelioma, is an uncommon benign vascular tumor.
  • RESULTS: The tumor was a well-circumscribed vascular proliferation of spindled to epithelioid endothelial cells.
  • Tumor cells with intracytoplasmic vascular lumens were present in several areas.
  • CONCLUSIONS: Spindle cell hemangioma rarely presents in the oral cavity and needs to be considered in the differential diagnosis of oral cavity vascular tumors to avoid misdiagnosis as a more aggressive vascular tumor.
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Hemangioendothelioma, Epithelioid / diagnosis. Hemangiosarcoma / diagnosis. Humans. Male. Sarcoma, Kaposi / diagnosis. Treatment Outcome

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  • (PMID = 17880587.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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66. Yoruk O, Erdem H, Mutlu V, Erdogan F, Altas E, Kantarci M: Epithelioid hemangioendothelioma of the submandibular gland. Auris Nasus Larynx; 2008 Mar;35(1):157-9
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  • [Title] Epithelioid hemangioendothelioma of the submandibular gland.
  • Epithelioid hemangioendothelioma (EH) is a seldom tumor of vascular origin, which occurs at sites such as liver, lung or soft tissues, and has a highly unpredictable malignant potential and clinical course.
  • We submitted a case with epithelioid hemangioendothelioma of submandibular gland.
  • The pathological result was interpretated as epithelioid hemangioendothelioma of the submandibular gland.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Submandibular Gland Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Calcinosis / diagnosis. Calcinosis / pathology. Calcinosis / surgery. Female. Humans. Submandibular Gland / pathology. Submandibular Gland / surgery. Tomography, X-Ray Computed

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  • (PMID = 17884320.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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67. Samaila MO: Malignant tumours of childhood in Zaria. Afr J Paediatr Surg; 2009 Jan-Jun;6(1):19-23
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  • All tissue biopsies were fixed in 10% formalin and processed in wax.
  • The vascular tumours included epithelioid haemangioendothelioma, haemangioblastoma and Dabska tumour and they accounted for (5.8%) of all tumours seen.

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  • (PMID = 19661660.001).
  • [ISSN] 0974-5998
  • [Journal-full-title] African journal of paediatric surgery : AJPS
  • [ISO-abbreviation] Afr J Paediatr Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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68. Hoti E, Adam R: Liver transplantation for primary and metastatic liver cancers. Transpl Int; 2008 Dec;21(12):1107-17
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  • Liver resection may offer similar survival results to orthotopic liver transplantation (OLT) in the short term, and does not carry the long-term effects of immunosuppression; however, long-term and disease-free survival favours liver transplantation.
  • Survival rate in these selected patients can approach that of patients with cholestatic liver disease, and the role of transplantation now requires re-evaluation.
  • Epithelioid hemangioendothelioma is also an appropriate indication for liver transplantation, even in the presence of extrahepatic metastases, unlike angiosarcoma which is associated with a very poor survival and considered as a contraindication.
  • And finally for metastatic liver disease from neuroendocrine tumours, liver transplantation can result in long-term survival and even cure in well selected patients.
  • [MeSH-minor] Bile Duct Neoplasms / surgery. Carcinoma, Hepatocellular / pathology. Carcinoma, Hepatocellular / surgery. Cholangiocarcinoma / surgery. Colorectal Neoplasms / pathology. Hemangioendothelioma / surgery. Hemangiosarcoma / surgery. Humans. Neoplasm Metastasis. Neoplasm Staging. Neuroendocrine Tumors / surgery. Survival Analysis. Survivors. Treatment Outcome

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  • (PMID = 18713148.001).
  • [ISSN] 0934-0874
  • [Journal-full-title] Transplant international : official journal of the European Society for Organ Transplantation
  • [ISO-abbreviation] Transpl. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 75
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69. Leblebicioglu G: Reliability of vascularized fibula in maintaining arthrodesis following extra-articular wide excisions of malignant musculoskeletal tumors. Saudi Med J; 2006 Aug;27(8):1204-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common diagnosis was malignant giant cell tumor (6), followed by Ewing's sarcoma (3), hemangioendothelioma (2), osteosarcoma (2) and chondrosarcoma (1).
  • Two patients with metastatic Ewing's sarcoma had metastatic disease.
  • [MeSH-major] Arthrodesis. Bone Neoplasms / surgery. Bone Transplantation. Fibula / blood supply. Fibula / transplantation

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  • [CommentIn] Saudi Med J. 2007 Jun;28(6):984 [17530131.001]
  • (PMID = 16883453.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Saudi Arabia
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70. Suppiah R, Wood L, Elson P, Budd GT: Phase I/II study of docetaxel, ifosfamide, and doxorubicin in advanced, recurrent, or metastatic soft tissue sarcoma (STS). Invest New Drugs; 2006 Nov;24(6):509-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase I/II study of docetaxel, ifosfamide, and doxorubicin in advanced, recurrent, or metastatic soft tissue sarcoma (STS).
  • HISTOLOGY: leiomyosarcoma 10, spindle cell sarcoma 3, synovial sarcoma 2, angiosarcoma 1, fibrous histiocytoma 1, epitheliod hemangio-endothelioma 1, and 3 not specified.

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  • (PMID = 16791410.001).
  • [ISSN] 0167-6997
  • [Journal-full-title] Investigational new drugs
  • [ISO-abbreviation] Invest New Drugs
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Taxoids; 15H5577CQD / docetaxel; 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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71. Terui K, Nakatani Y, Kambe M, Fukunaga M, Hishiki T, Saito T, Sato Y, Takenouchi A, Saito E, Ono S, Yoshida H: Kaposiform hemangioendothelioma of the choledochus. J Pediatr Surg; 2010 Sep;45(9):1887-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kaposiform hemangioendothelioma of the choledochus.
  • Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular neoplasm that mainly occurs during childhood.
  • Contrast computed tomography revealed a vascular tumor in the hepatic portal region causing biliary obstruction.
  • [MeSH-major] Cholestasis / surgery. Common Bile Duct Neoplasms / surgery. Hemangioendothelioma / surgery. Jaundice, Obstructive / surgery

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20850638.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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72. Lincoln DT, Singal PK, Al-Banaw A: Growth hormone in vascular pathology: neovascularization and expression of receptors is associated with cellular proliferation. Anticancer Res; 2007 Nov-Dec;27(6B):4201-18
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Growth hormone in vascular pathology: neovascularization and expression of receptors is associated with cellular proliferation.
  • Vascular tumours are common lesions of the skin and subcutaneous tissue, but also occur in many other tissues and internal organs.
  • The well-differentiated tumours consist of irregular anastomosing, blood-filled vascular channels that are lined by variably atypical endothelial cells.
  • Several growth factors, including basic fibroblast growth factor, transforming growth factors and vascular endothelial growth factor, play a role in tumour angiogenesis.
  • Growth hormone (GH) is mitogenic for a variety of vascular tissue cells, including smooth muscle cells, fibroblasts and endothelial cells and exerts its regulatory functions in controlling metabolism, balanced growth and differentiated cell expression by acting on specific membrane-bound receptors, which trigger a phosphorylation cascade resulting in the modulation of numerous signalling pathways and of gene expression.
  • To address the site/mode of action through which GH exerts its effects, a well characterized monoclonal antibody, obtained by hybridoma technology from Balb/c mice immunized with purified rabbit and rat liver GH-receptor (GHR) and directed against the hormone binding site of the receptor, was applied, using the ABC technique to determine GHR expression in a panel of vascular tumours.
  • A total of 64 benign and malignant vascular tumours were obtained from different human organ sites, including the chest wall, skin, axillary contents, duodenum, female breast, abdomen, stomach, colon, lymph node, bladder, body flank and neck regions.
  • The tumours were of the following pathological entities: Haemangioma (n = 12); haemangioendothelioma (n = 10); Castleman's disease (n = 3), haemangiopericytoma (n = 4); angiosarcoma, (n = 11), Kaposi's sarcoma with focal infiltration by lymphoma, HIV +ve (n = 7), Kaposi's sarcoma (n = 17).
  • Results show that, compared to their normal tissue counterparts, nuclear and cytoplasmic expression of GHR consistently result in strong receptor immunoreactivity in the highly malignant angiosarcomas and Kaposi's sarcomas and was localized in the cell membranes and cytoplasm, but strong nuclear immunoreactivity was also identified.
  • In conclusion, this study shows that GHR expression in vascular tumours is a function of malignancy and cancer progression.
  • The presence of GHR in endothelial cells of vascular neoplasm indicates that they are target cells and GH is of importance in the proliferation of vascular tumour angiogenesis.
  • The results support the hypothesis that GH is involved in the paracrine-autocrine mechanism, acting locally in regulating vascular tumour growth and will be useful for site-specific studies of the evolution of vascular cancers.
  • [MeSH-major] Growth Hormone / metabolism. Receptors, Somatotropin / biosynthesis. Vascular Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Animals. Antibodies, Monoclonal / immunology. Antibodies, Monoclonal / pharmacology. Binding Sites. Cell Growth Processes / physiology. Female. Hemangioma / blood supply. Hemangioma / metabolism. Hemangioma / pathology. Humans. Male. Mice. Mice, Inbred BALB C. Middle Aged. Neovascularization, Pathologic / metabolism. Neovascularization, Pathologic / pathology. Rabbits. Rats

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  • [ErratumIn] Anticancer Res. 2008 Mar-Apr;28(2b):1439
  • (PMID = 18225592.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Receptors, Somatotropin; 9002-72-6 / Growth Hormone
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73. Shah ZK, Peh WC, Shek TW, Wong JW, Chien EP: Hemangioendothelioma with an epithelioid phenotype arising in hemangioma of the fibula. Skeletal Radiol; 2005 Nov;34(11):750-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemangioendothelioma with an epithelioid phenotype arising in hemangioma of the fibula.
  • The classification of certain vascular bone tumors that show an epithelioid cytologic appearance remains confusing, with overlap in features of epithelioid hemangioma, hemangioendothelioma and epithelioid hemangioendothelioma.
  • Open biopsy showed hemangioendothelioma with epithelioid morphology, and the lesion was completely resected with reconstruction using a peroneal fibular rotation graft.
  • Examination of the resected specimen showed focal hemangioendothelioma with an epithelioid phenotype arising in a hemangioma.
  • This case illustrates the difficulty and pitfalls of making the correct diagnosis on the basis of a small biopsy specimen.
  • [MeSH-major] Ankle Joint / pathology. Bone Neoplasms / diagnosis. Fibula / pathology. Hemangioendothelioma, Epithelioid / diagnosis. Hemangioma / diagnosis. Neoplasms, Multiple Primary / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Radiography

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  • (PMID = 15834563.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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74. Chang JM, Kwon BJ, Han MH, Kang HS, Chang KH: Kaposiform hemangioendothelioma arising from the internal auditory canal. AJNR Am J Neuroradiol; 2006 Apr;27(4):931-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kaposiform hemangioendothelioma arising from the internal auditory canal.
  • Kaposiform hemangioendothelioma is a rare vascular tumor and locally aggressive endothelial-derived spindle cell neoplasm, which occurs almost exclusively in infants and adolescents.
  • Radiologically, hemangioendothelioma, including Kaposiform hemangioendothelioma, is seen as a highly vascularized well-enhancing tumor, but no characteristic findings differentiate Kaposiform hemangioendothelioma from other soft-tissue tumors, particularly when the tumor is too small to have any locally aggressive features or identifiable large vessels.
  • We present a case of Kaposiform hemangioendothelioma in the internal auditory canal that had no differential features on initial MR images and rapidly grew into a huge mass in a few months.
  • [MeSH-major] Ear Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Labyrinth Diseases / diagnosis. Sarcoma, Kaposi / diagnosis

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  • (PMID = 16611794.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Darouassi Y, Errami N, El Marjany M, Abrouq A, Azendour B: [Spindle-cell hemangioendothelioma of the pharynx managed by radiotherapy]. Cancer Radiother; 2006 Dec;10(8):583-5
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  • [Title] [Spindle-cell hemangioendothelioma of the pharynx managed by radiotherapy].
  • [MeSH-major] Hemangioendothelioma / radiotherapy. Neoplasm Recurrence, Local / radiotherapy. Pharyngeal Neoplasms / radiotherapy

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  • (PMID = 16766220.001).
  • [ISSN] 1278-3218
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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76. Singh S, Chowdhury V, Prakash A, Aggarwal A: Infantile haemangio-endothelioma of liver: a case report. J Indian Med Assoc; 2008 Feb;106(2):120, 122
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  • [Title] Infantile haemangio-endothelioma of liver: a case report.
  • Infantile haemangio-endothelioma of liver is the most common symptomatic vascular tumour of liver.
  • The findings suggested an infantile haemangio-endothelioma of the liver.
  • [MeSH-major] Hemangioendothelioma / radiography. Hemangioendothelioma / ultrasonography. Liver Neoplasms / radiography. Liver Neoplasms / ultrasonography
  • [MeSH-minor] Diagnosis, Differential. Female. Follow-Up Studies. Humans. Infant. Neoplasm Regression, Spontaneous. Tomography, X-Ray Computed / methods

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  • (PMID = 18705257.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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77. Shang A, Wang X: Pulmonary epithelioid haemangioendothelioma mimicking central lung cancer. Respirology; 2009 Apr;14(3):452-5
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  • [Title] Pulmonary epithelioid haemangioendothelioma mimicking central lung cancer.
  • Endobronchial biopsy suggested a pulmonary epithelioid haemangioendothelioma.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adult. Bronchoscopy. Diagnosis, Differential. Fatal Outcome. Female. Humans

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  • (PMID = 19341425.001).
  • [ISSN] 1440-1843
  • [Journal-full-title] Respirology (Carlton, Vic.)
  • [ISO-abbreviation] Respirology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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78. Walsh MA, Carcao M, Pope E, Lee KJ: Kaposiform hemangioendothelioma presenting antenatally with a pericardial effusion. J Pediatr Hematol Oncol; 2008 Oct;30(10):761-3
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  • [Title] Kaposiform hemangioendothelioma presenting antenatally with a pericardial effusion.
  • Investigations and management consisted of repeat pericardiocentesis, platelet and red blood cell transfusions, laryngoscopy, creation of a pericardial window, and biopsy of the mediastinal mass.
  • Diagnosis was made of Kaposiform hemangioendothelioma surrounding the base of the heart, trachea, and esophagus as well as Kasabach-Merritt phenomenon.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Pericardial Effusion / etiology
  • [MeSH-minor] Disease Management. Humans. Infant. Prednisone / therapeutic use. Vincristine / therapeutic use


79. Abuzallouf S, Wong R, Mintz AP, Provias J: Hemangioendothelioma of the spinal cord with intramedullary extension. Med Princ Pract; 2005 Sep-Oct;14(5):354-7
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  • [Title] Hemangioendothelioma of the spinal cord with intramedullary extension.
  • OBJECTIVE: Hemangioendotheliomas (HE) are vascular neoplasms that rarely involve the neuraxis.
  • The tumor was resected and postoperative radiotherapy was delivered for residual disease.
  • No disease was seen on MRI after 48 months of clinical and radiological follow-up.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Spinal Cord Neoplasms / diagnosis

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  • (PMID = 16103703.001).
  • [ISSN] 1011-7571
  • [Journal-full-title] Medical principles and practice : international journal of the Kuwait University, Health Science Centre
  • [ISO-abbreviation] Med Princ Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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80. Adler B, Naheedy J, Yeager N, Nicol K, Klamar J: Multifocal epithelioid hemangioendothelioma in a 16-year-old boy. Pediatr Radiol; 2005 Oct;35(10):1014-8
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  • [Title] Multifocal epithelioid hemangioendothelioma in a 16-year-old boy.
  • Excisional biopsy from several sites confirmed the diagnosis of epithelioid hemangioendothelioma.
  • We conclude that epithelioid hemangioendothelioma should be added to the differential diagnosis for lytic lesions of bone that are clustered in the same anatomic region and that might also present with visceral involvement.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis
  • [MeSH-minor] Adolescent. Bone Neoplasms / diagnosis. Cervical Vertebrae / pathology. Headache / etiology. Humans. Kidney Neoplasms / diagnosis. Liver Neoplasms / diagnosis. Lung Neoplasms / diagnosis. Magnetic Resonance Imaging. Male. Skull Base Neoplasms / diagnosis. Spinal Neoplasms / diagnosis. Syncope / etiology. Tomography, X-Ray Computed

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  • (PMID = 15912411.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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81. Tamai N, Hashii Y, Osuga K, Chihara T, Morii E, Aozasa K, Yoshikawa H: Kaposiform hemangioendothelioma arising in the deltoid muscle without the Kasabach-Merritt phenomenon. Skeletal Radiol; 2010 Oct;39(10):1043-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kaposiform hemangioendothelioma arising in the deltoid muscle without the Kasabach-Merritt phenomenon.
  • Kaposiform hemangioendothelioma (KHE) is a rare tumor that occurs nearly exclusively during infancy and childhood.
  • It has features common to both capillary hemangioma and Kaposi sarcoma and for that reason many terms have been used for these tumors including "Kaposi-like infantile hemangioendothelioma" and "hemangioma with Kaposi sarcoma-like features."
  • Knowledge of the radiological findings of this uncommon tumor might be helpful for diagnosis.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis
  • [MeSH-minor] Antineoplastic Agents, Hormonal / therapeutic use. Deltoid Muscle / pathology. Deltoid Muscle / ultrastructure. Diagnosis, Differential. Disseminated Intravascular Coagulation. Hemangioendothelioma / diagnosis. Hemangioendothelioma / drug therapy. Hemangioendothelioma / ultrastructure. Hemangioma, Capillary. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / drug therapy. Hemangioma, Cavernous / ultrastructure. Humans. Infant. Kasabach-Merritt Syndrome. Magnetic Resonance Imaging / methods. Male. Prednisolone / therapeutic use. Sarcoma, Kaposi / diagnosis. Sarcoma, Kaposi / drug therapy. Sarcoma, Kaposi / ultrastructure. Skin Neoplasms / diagnosis. Skin Neoplasms / drug therapy. Skin Neoplasms / ultrastructure. Thrombocytopenia / diagnosis. Thrombocytopenia / drug therapy. Treatment Outcome. Vascular Neoplasms / diagnosis. Vascular Neoplasms / drug therapy. Vascular Neoplasms / ultrastructure

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  • (PMID = 20309545.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 9PHQ9Y1OLM / Prednisolone; Kaposiform Hemangioendothelioma
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82. Moon SB, Kwon HJ, Park KW, Yun WJ, Jung SE: Clinical experience with infantile hepatic hemangioendothelioma. World J Surg; 2009 Mar;33(3):597-602
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical experience with infantile hepatic hemangioendothelioma.
  • BACKGROUND: Infantile hepatic hemangioendothelioma (IHHE) is a rare disorder with only a few series reported in the medical literature.
  • Thirteen patients had a unilobar single tumor and three patients had bilobar disease.
  • Two patients with bilobar disease showed elevated levels of serum alpha-fetoprotein at presentation.
  • [MeSH-major] Hemangioendothelioma. Liver Neoplasms

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  • (PMID = 19132441.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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83. Güven A, Aygun C, Ince H, Aydin M, Pinarli FG, Baysal K, Küçüködük S: Severe hypothyroidism caused by hepatic hemangioendothelioma in an infant of a diabetic mother. Horm Res; 2005;63(2):86-9
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  • [Title] Severe hypothyroidism caused by hepatic hemangioendothelioma in an infant of a diabetic mother.
  • Hemangioendotheliomas can express type 3 iodothyronine deiodinase and cause severe hypothyroidism.
  • Here we report an infant of a diabetic mother with hypothyroidism caused by liver hemangioendothelioma.
  • Consumptive hypothyroidism should be an indicator to search for a vascular tumor in infants.
  • [MeSH-major] Hemangioendothelioma / complications. Hypothyroidism / etiology. Liver Neoplasms / complications. Pregnancy in Diabetics

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  • [Copyright] Copyright (c) 2005 S. Karger AG, Basel.
  • (PMID = 15711094.001).
  • [ISSN] 0301-0163
  • [Journal-full-title] Hormone research
  • [ISO-abbreviation] Horm. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] EC 1.11.1.- / iodothyronine deiodinase type III; EC 1.11.1.8 / Iodide Peroxidase
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84. Neves N, Lima-Rodrigues F, Ribeiro-Silva M, Cacho-Rodrigues P, Eloy C, Paiva ME, Pinto R: Epithelioid hemangioendothelioma presenting as a vertebral fracture. Acta Reumatol Port; 2010 Jul-Sep;35(3):370-4
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  • [Title] Epithelioid hemangioendothelioma presenting as a vertebral fracture.
  • Epithelioid hemagioendothelioma (EH) is a rare vascular tumor with an intermediate biological behavior between hemangioma and angiosarcoma.
  • Anatomopathological study revealed an epithelioid vascular neoplasm with low mitotic index, and tumor cells reactive to vimentin, CD31 and CD34, leading to the diagnosis of Grade I Epithelioid Hemangioendothelioma.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / complications. Lumbar Vertebrae / injuries. Spinal Fractures / etiology

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  • (PMID = 20975643.001).
  • [ISSN] 0303-464X
  • [Journal-full-title] Acta reumatológica portuguesa
  • [ISO-abbreviation] Acta Reumatol Port
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Portugal
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85. Mittelbronn M, Schittenhelm J, Ritz R, Hahn U, Bornemann A, Roser F: Spinal cord compression through extraosseous extension of a vertebral low-grade hemangioendothelioma with histiocytoid differentiation. Clin Neuropathol; 2008 Sep-Oct;27(5):351-6
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  • [Title] Spinal cord compression through extraosseous extension of a vertebral low-grade hemangioendothelioma with histiocytoid differentiation.
  • The resected tumor mass exhibited a highly vascularized tumor with architectural complexity and high cellularity finally leading to the diagnosis of a hemangioendothelioma.
  • Interesting was the fact that the tumor vasculature exhibited many CD68-positive cells protruding into the lumen and, therefore, being part of a partially histiocytoid differentiation which is all the more uncommon in hemangioendothelioma.
  • Usually, hemangioendotheliomas arise from the soft tissue, lungs or liver, but intraspinal manifestations are only rarely observed.
  • Furthermore, the clinical course with a progressive development of a paraparesis due to a hemangioendothelioma is very uncommon.
  • [MeSH-major] Hemangioendothelioma / complications. Hemangioendothelioma / pathology. Spinal Cord Compression / etiology. Spinal Neoplasms / complications. Spinal Neoplasms / pathology

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  • (PMID = 18808067.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human
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86. Kalra N, Kochhar R, Vaiphei K, Virmani V, Yadav TD, Khandelwal N: Coexistent hepatic and pulmonary epitheloid hemangioendothelioma. Indian J Cancer; 2009 Jan-Mar;46(1):61-3
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  • [Title] Coexistent hepatic and pulmonary epitheloid hemangioendothelioma.
  • Epitheloid hemangioendothelioma (EHE) is a rare neoplasm of vascular origin known to arise in soft tissue, liver and lung.
  • We describe a case of coexistent hepatic and pulmonary epitheloid hemangioendothelioma, proven on autopsy, and review the histological and radiological features of epitheloid hemangioendothelioma.
  • Large confluent masses, peripheral location with capsular retraction, hypertrophy of uninvolved liver, invasion of portal and hepatic veins, enhancing margins and delayed enhancement and dense calcification are the typical features which provide a clue to diagnosis of hepatic EHE.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Liver Neoplasms / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Aged. Autopsy. Diagnosis, Differential. Fatal Outcome. Female. Humans. Tomography, X-Ray Computed

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  • (PMID = 19282569.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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87. Gupta NP, Kolla SB, Panda S, Sharma MC: Epitheloid hemangioendothelioma of urinary bladder. Indian J Urol; 2008 Apr;24(2):253-5

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  • [Title] Epitheloid hemangioendothelioma of urinary bladder.
  • Epitheloid hemangioendothelioma is an uncommon vascular neoplasm and has an unpredictable clinical behavior.
  • Most often, epitheloid hemangioendothelioma arise from the soft tissues of the upper and lower extremities and it has borderline malignant potential.
  • We describe the first reported case of epitheloid hemangioendothelioma in the urinary bladder, which was treated by transurethral resection.
  • The diagnosis was confirmed by immunohistochemistry.

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  • [Cites] Urology. 1998 Nov;52(5):778-84 [9801098.001]
  • [Cites] Am J Surg Pathol. 1997 Apr;21(4):363-74 [9130982.001]
  • [Cites] Cancer. 1982 Sep 1;50(5):970-81 [7093931.001]
  • (PMID = 19468406.001).
  • [ISSN] 0970-1591
  • [Journal-full-title] Indian journal of urology : IJU : journal of the Urological Society of India
  • [ISO-abbreviation] Indian J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2684281
  • [Keywords] NOTNLM ; Hemangioendothelioma / urinary bladder
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88. Hartman KR, Moncur JT, Minniti CP, Creamer KM: Mediastinal Kaposiform hemangioendothelioma and Kasabach-Merritt phenomenon in an infant: treatment with interferon. J Pediatr Hematol Oncol; 2009 Sep;31(9):690-2
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  • [Title] Mediastinal Kaposiform hemangioendothelioma and Kasabach-Merritt phenomenon in an infant: treatment with interferon.
  • A 2-week-old infant developed respiratory failure due to a mediastinal Kaposiform hemangioendothelioma that was complicated by thrombocytopenia and consumptive coagulopathy.
  • Multiple transfusions with fresh frozen plasma, platelets, and red blood cells were needed for the consumptive coagulopathy, and ventilatory support was required for 5 months.
  • This case demonstrates that interferon can be used to treat infants with Kaposiform hemangioendothelioma in life-threatening situations that do not respond to other forms of treatment.
  • [MeSH-major] Anemia, Hemolytic / etiology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Disseminated Intravascular Coagulation / etiology. Hemangioendothelioma / complications. Interferon-alpha / therapeutic use. Mediastinal Neoplasms / complications. Respiratory Insufficiency / etiology. Thrombocytopenia / etiology
  • [MeSH-minor] Aminocaproates / administration & dosage. Blood Component Transfusion. Combined Modality Therapy. Female. Humans. Infant, Newborn. Methylprednisolone / administration & dosage. Plasma. Respiration, Artificial. Syndrome. Thoracotomy. Thymectomy. Vincristine / administration & dosage

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  • (PMID = 19687760.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aminocaproates; 0 / Interferon-alpha; 5J49Q6B70F / Vincristine; X4W7ZR7023 / Methylprednisolone
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89. Fernandez S, Cook GW, Arber DA: Metastasizing splenic littoral cell hemangioendothelioma. Am J Surg Pathol; 2006 Aug;30(8):1036-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasizing splenic littoral cell hemangioendothelioma.
  • A single prior description of a littoral cell hemangioendothelioma showed nuclear atypia and necrosis, and this is the first case report of a splenic littoral cell hemangioendothelioma with a completely bland histologic appearance.
  • [MeSH-major] Hemangioendothelioma / secondary. Liver Neoplasms / secondary. Retroperitoneal Neoplasms / secondary. Splenic Neoplasms / pathology

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  • (PMID = 16861977.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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90. Falleti J, Siano M, De Cecio R, Somma A, Pettinato G, Insabato L: Nodal and extranodal soft tissue polymorphous hemangioendothelioma: a case report and review of the literature. Tumori; 2009 Jan-Feb;95(1):94-7
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  • [Title] Nodal and extranodal soft tissue polymorphous hemangioendothelioma: a case report and review of the literature.
  • BACKGROUND: Polymorphous hemangioendothelioma is a rare vascular tumor of borderline malignant potential and only 10 cases have been described in the literature so far.
  • METHODS AND RESULTS: We report a case of nodal and extranodal polymorphous hemangioendothelioma and review the literature.
  • The main nodule was composed of angiosarcoma-like areas mixed with angiomatous features; some vascular spaces with hobnail endothelium were seen.
  • CONCLUSIONS: Polymorphous hemangioendothelioma is a distinct entity in the hemangioendothelioma group with its own clinical and histological features.
  • [MeSH-major] Hemangioendothelioma / pathology. Lymph Nodes / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Aged. Biopsy, Fine-Needle. Humans. Immunohistochemistry. Male. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / therapy. Oral Surgical Procedures. Radiotherapy

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  • (PMID = 19366064.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 10
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91. Jeong SW, Woo HY, You CR, Huh WH, Bae SH, Choi JY, Yoon SK, Jung CK, Jung ES: [A case of hepatic epithelioid hemangioendothelioma that caused extrahepatic metastases without intrahepatic recurrence after hepatic resection]. Korean J Hepatol; 2008 Dec;14(4):525-31
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  • [Title] [A case of hepatic epithelioid hemangioendothelioma that caused extrahepatic metastases without intrahepatic recurrence after hepatic resection].
  • Epithelioid hemangioendothelioma is a neoplasm of vascular origin with a low-to-intermediate malignant potential and is one of the rare sarcomas arising from the liver.
  • We report a case of a 64-year old woman who underwent hepatic resection due to epithelioid hemangioendothelioma in the right lobe that progressed to extrahepatic metastases of the bone, pleura, and peritoneum 22 months later.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Hemangioendothelioma, Epithelioid / secondary. Liver Neoplasms / diagnosis
  • [MeSH-minor] Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Bone Neoplasms / secondary. Female. Hepatectomy. Humans. Lung Neoplasms / diagnosis. Lung Neoplasms / pathology. Lung Neoplasms / secondary. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 19119248.001).
  • [ISSN] 1738-222X
  • [Journal-full-title] The Korean journal of hepatology
  • [ISO-abbreviation] Korean J Hepatol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
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92. Jothilakshmi K, Matthai J, Paul S, Singal AK: Symptomatic hepatic hemangioendothelioma in a newborn. Indian Pediatr; 2006 Oct;43(10):908-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic hepatic hemangioendothelioma in a newborn.
  • A case of hepatic hemangioendothelioma presenting as congestive cardiac failure in a neonate is reported.
  • [MeSH-major] Hemangioendothelioma / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Disease Progression. Female. Glucocorticoids / therapeutic use. Humans. Infant, Newborn. Prednisolone / therapeutic use

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  • (PMID = 17079836.001).
  • [ISSN] 0019-6061
  • [Journal-full-title] Indian pediatrics
  • [ISO-abbreviation] Indian Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Glucocorticoids; 9PHQ9Y1OLM / Prednisolone
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93. Weinreb I, Cunningham KS, Perez-Ordoñez B, Hwang DM: CD10 is expressed in most epithelioid hemangioendotheliomas: a potential diagnostic pitfall. Arch Pathol Lab Med; 2009 Dec;133(12):1965-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD10 is expressed in most epithelioid hemangioendotheliomas: a potential diagnostic pitfall.
  • CONTEXT: -Epithelioid hemangioendothelioma (EHE) is a vascular neoplasm that occasionally is difficult to distinguish from primary/metastatic carcinomas, particularly when EHEs express keratins.
  • All EHEs were positive for vascular markers.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Hemangioendothelioma, Epithelioid / metabolism. Neprilysin / biosynthesis
  • [MeSH-minor] Adult. Aged. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / metabolism. Diagnosis, Differential. Epithelioid Cells / chemistry. Epithelioid Cells / pathology. Female. Hemangiosarcoma / diagnosis. Hemangiosarcoma / metabolism. Humans. Immunohistochemistry. Kidney Neoplasms / diagnosis. Kidney Neoplasms / metabolism. Male. Middle Aged. Sensitivity and Specificity. Young Adult

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  • (PMID = 19961253.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; EC 3.4.24.11 / Neprilysin
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94. Dhawan SS, Raza M: Spindle cell hemangioendothelioma. Cutis; 2007 Feb;79(2):125-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spindle cell hemangioendothelioma.
  • Prior to the 1980s, the term hemangioendothelioma (HE) loosely applied to a spectrum of vascular tumors ranging from benign tumors, such as capillary hemangiomas, to fully malignant angiosarcomas.
  • In the early 1980s, the term epithelioid HE was used to describe a heterogeneous group of vascular tumors with an intermediate clinical course between hemangiomas and conventional angiosarcomas, thereby bringing to notice the borderline nature of these tumors.
  • [MeSH-major] Hemangioendothelioma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 17388212.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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95. Schattenberg T, Kam R, Klopp M, Herpel E, Schnabel PA, Mechtersheimer G, Dienemann H, Pfannschmidt J: Pulmonary epithelioid hemangioendothelioma: report of three cases. Surg Today; 2008;38(9):844-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary epithelioid hemangioendothelioma: report of three cases.
  • Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumor of low-grade malignancy, the prognosis of which remains unpredictable.
  • [MeSH-major] Hemangioendothelioma, Epithelioid. Lung Neoplasms

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  • (PMID = 18751952.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 30
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96. Shin DH, Chen M, Niemeier LA: Primary epithelioid hemangioendothelioma of the kidney and penis. Can J Urol; 2010 Dec;17(6):5480-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary epithelioid hemangioendothelioma of the kidney and penis.
  • Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor of low malignant potential most commonly found in the lung, liver, and soft tissues.
  • [MeSH-major] Carcinoma / pathology. Esophageal Neoplasms / pathology. Hemangioendothelioma, Epithelioid / pathology. Kidney Neoplasms / pathology. Neoplasms, Second Primary / pathology. Penile Neoplasms / pathology

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  • (PMID = 21172116.001).
  • [ISSN] 1195-9479
  • [Journal-full-title] The Canadian journal of urology
  • [ISO-abbreviation] Can J Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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97. Scordi-Bello IA, Snyder A, Schwartz M, Fallon JT: Intravascular epithelioid hemangioendothelioma of the inferior vena cava: case report of an unusual and unpredictable vascular tumor. Cardiovasc Pathol; 2009 Jul-Aug;18(4):243-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intravascular epithelioid hemangioendothelioma of the inferior vena cava: case report of an unusual and unpredictable vascular tumor.
  • Vascular neoplasms are uncommon and pose a diagnostic and treatment challenge to the pathologist and surgeon, respectively.
  • Epithelioid hemangioendothelioma is a rare neoplasm of vascular origin with an unknown etiology.
  • Intravascular epithelioid hemangioendotheliomas have been described more often in veins than arteries, and there are only about 30 reports in the English literature.
  • We report here the case of an epithelioid hemangioendothelioma of the inferior vena cava, which presented with abdominal pain, ascites and pedal edema.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / pathology. Vascular Neoplasms / pathology. Vena Cava, Inferior / pathology
  • [MeSH-minor] Abdominal Pain / etiology. Adult. Ascites / etiology. Blood Vessel Prosthesis Implantation. Edema / etiology. Humans. Immunohistochemistry. Magnetic Resonance Angiography. Male. Treatment Outcome

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  • (PMID = 18417368.001).
  • [ISSN] 1879-1336
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Tokyol C, Uzüm N, Kuru I, Uluoglu O: Epithelioid sarcoma-like hemangioendothelioma: a case report. Tumori; 2005 Sep-Oct;91(5):436-9
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  • [Title] Epithelioid sarcoma-like hemangioendothelioma: a case report.
  • Seven cases of an unusual low-grade vascular tumor were reported in a recent study.
  • Despite its similarity to epithelioid sarcoma, this tumor was termed epithelioid sarcoma-like hemangioendothelioma because of the subtle histopathological and immunohistochemical differences.
  • [MeSH-major] Elbow. Hemangioendothelioma. Sarcoma

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  • (PMID = 16459644.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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99. Brimo F, Nahal A: Malignant epithelioid hemangioendothelioma with spindle phenotype: report of an unusual case diagnosed by fine needle aspiration cytology. Acta Cytol; 2008 Nov-Dec;52(6):721-4
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  • [Title] Malignant epithelioid hemangioendothelioma with spindle phenotype: report of an unusual case diagnosed by fine needle aspiration cytology.
  • BACKGROUND: Epithelioid hemangioendothelioma (EHE) is a rare sarcoma of vascular differentiation that involves various sites and is rarely diagnosed by cytology.
  • The tumor expressed vascular markers and was labeled as malignant EHE because of the spindle cell morphology, marked cellularity and presence of necrosis.
  • CONCLUSION: On cytology, malignant EHE is a very difficult diagnosis to render, especially when the tumor displays spindle cell morphology.
  • Including endothelial markers in the immunohistochemical panel is crucial to reach the diagnosis.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Hemangioendothelioma, Epithelioid / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19068679.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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100. Leleu O, Lenglet F, Clarot C, Kleinmann P, Jounieaux V: [Pulmonary epithelioid haemangioendothelioma: reports of three cases and a review of the literature]. Rev Mal Respir; 2010 Sep;27(7):778-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pulmonary epithelioid haemangioendothelioma: reports of three cases and a review of the literature].
  • INTRODUCTION: Pulmonary epithelioid haemangioendothelioma (PEH) is a rare vascular tumour of intermediate malignancy that predominantly affects women.
  • In the first case, the disease was multifocal and needed to be treated with several pulmonary resections.
  • The diagnosis is confirmed by immuno-chemical analysis of a lung biopsy.
  • No standard treatment has been validated and no treatment is necessary if the disease is asymptomatic.
  • Usually the evolution is slow except when the disease is complicated by haemoptysis, pleural effusion, haemothorax, mediastinal lymphadenopathy or hepatic spread.
  • [MeSH-major] Hemangioendothelioma, Epithelioid. Lung Neoplasms

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  • [Copyright] Copyright © 2010 SPLF. Published by Elsevier Masson SAS. All rights reserved.
  • (PMID = 20863982.001).
  • [ISSN] 1776-2588
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
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