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1. Almaraz RL, Gutiérrez JC, Bieler CB, Hernández AH, González ME, Villar GR: [Infantile vascular tumors]. An Pediatr (Barc); 2010 Feb;72(2):143.e1-143.e15
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  • [Transliterated title] Tumores vasculares en la infancia.
  • Hemangiomas of infancy are by far the most frequent, and other less common types are congenital hemangiomas (rapidly involuting or RICH and non-involuting or NICH), kaposiform hemangioendothelioma, angioblastoma or tufted angioma and pyogenic granuloma.

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  • (PMID = 20022827.001).
  • [ISSN] 1695-9531
  • [Journal-full-title] Anales de pediatría (Barcelona, Spain : 2003)
  • [ISO-abbreviation] An Pediatr (Barc)
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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2. Hei Y, Wang Y, Zhang XW, Xiao LH: [Hemangioblastoma of the optic nerve: a case report]. Zhonghua Bing Li Xue Za Zhi; 2005 Jul;34(7):392
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  • [Title] [Hemangioblastoma of the optic nerve: a case report].
  • [MeSH-major] Hemangioblastoma / pathology. Optic Nerve / pathology. Optic Nerve Neoplasms / pathology

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  • (PMID = 16251040.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Vimentin; 0 / von Willebrand Factor; EC 4.2.1.11 / Phosphopyruvate Hydratase
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3. Ferrandiz-Pulido C, Mollet J, Sabado C, Ferrer B, Garcia-Patos V: Tufted angioma associated with Kasabach-Merritt phenomenon: a therapeutic challenge. Acta Derm Venereol; 2010 Sep;90(5):535-7
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  • [Title] Tufted angioma associated with Kasabach-Merritt phenomenon: a therapeutic challenge.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Skin / drug effects
  • [MeSH-minor] Biopsy. Child, Preschool. Disseminated Intravascular Coagulation / blood. Disseminated Intravascular Coagulation / diagnosis. Disseminated Intravascular Coagulation / drug therapy. Disseminated Intravascular Coagulation / pathology. Female. Hemangioma / blood. Hemangioma / diagnosis. Hemangioma / drug therapy. Hemangioma / pathology. Hemangioma, Capillary / blood. Hemangioma, Capillary / diagnosis. Hemangioma, Capillary / drug therapy. Hemangioma, Capillary / pathology. Humans. Infant. Kasabach-Merritt Syndrome. Platelet Count. Skin Neoplasms / blood. Skin Neoplasms / diagnosis. Skin Neoplasms / drug therapy. Skin Neoplasms / pathology. Time Factors. Treatment Outcome

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  • (PMID = 20814640.001).
  • [ISSN] 1651-2057
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Sweden
  • [Chemical-registry-number] Tufted angioma
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4. Kalof AN, Cooper K: D2-40 immunohistochemistry--so far! Adv Anat Pathol; 2009 Jan;16(1):62-4
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  • Since its introduction, D2-40 immunoexpression has been described in a variety of lymphovascular neoplasms including lymphangioma, Kaposi sarcoma, and hemangioendothelioma, as well as nonvascular neoplasms such as epithelioid mesothelioma, seminoma, and hemangioblastoma.
  • More recently, D2-40 immunoexpression has been reported in primary adrenal cortical tumors, schwannomas, and adnexal tumors of the skin.
  • [MeSH-minor] Adrenal Cortex Neoplasms / immunology. Adrenal Cortex Neoplasms / pathology. Antibodies, Monoclonal, Murine-Derived. Antigens, CD / analysis. Central Nervous System Neoplasms / immunology. Central Nervous System Neoplasms / pathology. Endothelium, Lymphatic / immunology. Endothelium, Lymphatic / pathology. Hemangioblastoma / immunology. Hemangioblastoma / pathology. Humans. Immunohistochemistry. Lymphangioma / immunology. Lymphangioma / pathology. Mesothelioma / immunology. Mesothelioma / pathology. Sarcoma, Kaposi / immunology. Sarcoma, Kaposi / pathology

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  • (PMID = 19098468.001).
  • [ISSN] 1533-4031
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / monoclonal antibody D2-40
  • [Number-of-references] 14
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5. Casarin A, Martella M, Polli R, Leonardi E, Anesi L, Murgia A: Molecular characterization of large deletions in the von Hippel-Lindau (VHL) gene by quantitative real-time PCR: the hypothesis of an alu-mediated mechanism underlying VHL gene rearrangements. Mol Diagn Ther; 2006;10(4):243-9
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  • [Title] Molecular characterization of large deletions in the von Hippel-Lindau (VHL) gene by quantitative real-time PCR: the hypothesis of an alu-mediated mechanism underlying VHL gene rearrangements.
  • INTRODUCTION: Mutations of the von Hippel-Lindau (VHL) gene are responsible for VHL disease.
  • This is a familial autosomal-dominant syndrome, predisposing to the development of benign and malignant tumors, including CNS and retinal hemangioblastomas, pheochromocytomas, and clear cell renal carcinomas.
  • At least 30% of the disease-causing mutations in the VHL gene involve large alterations.
  • The results of our study and the complete characterization of a large deletion lead to the hypothesis that an Alu-mediated mechanism may be responsible for the common occurrence of large alterations in the VHL gene.
  • [MeSH-major] Alu Elements / genetics. Recombination, Genetic. Sequence Deletion. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics

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  • [Cites] Blood Cells Mol Dis. 2002 Jan-Feb;28(1):57-62 [11987242.001]
  • [Cites] Blood. 2003 Feb 15;101(4):1591-5 [12393546.001]
  • [Cites] Methods. 2001 Dec;25(4):402-8 [11846609.001]
  • [Cites] Blood. 2003 Aug 1;102(3):1097-9 [12702509.001]
  • [Cites] Science. 2004 Jul 23;305(5683):525-8 [15273396.001]
  • [Cites] Mol Genet Metab. 1999 Jul;67(3):183-93 [10381326.001]
  • [Cites] Medicine (Baltimore). 1997 Nov;76(6):381-91 [9413424.001]
  • [Cites] Blood. 1987 Jul;70(1):293-300 [3593968.001]
  • [Cites] Science. 1993 May 28;260(5112):1317-20 [8493574.001]
  • [Cites] Hum Genet. 1994 Jan;93(1):53-8 [8270255.001]
  • [Cites] Science. 1995 Sep 8;269(5229):1444-6 [7660130.001]
  • [Cites] Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2156-61 [9122164.001]
  • [Cites] Science. 1995 Sep 8;269(5229):1402-6 [7660122.001]
  • [Cites] Nat Genet. 2004 Sep;36(9):949-51 [15286789.001]
  • [Cites] J Assoc Genet Technol. 2004;30(2):41-47 [15345864.001]
  • [Cites] Genes Dev. 1999 Jul 15;13(14 ):1822-33 [10421634.001]
  • [Cites] Hum Mol Genet. 1994 Aug;3(8):1303-8 [7987306.001]
  • [Cites] Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7205-9 [8394013.001]
  • [Cites] Nat Med. 1995 Aug;1(8):822-6 [7585187.001]
  • [Cites] Cancer Res. 1995 Oct 15;55(20):4544-8 [7553625.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12436-41 [10535940.001]
  • [Cites] Hum Mutat. 1998;12 (6):417-23 [9829911.001]
  • [Cites] Mol Cell Biol. 1998 Feb;18(2):732-41 [9447969.001]
  • [Cites] Proc Natl Acad Sci U S A. 1986 Jun;83(11):3875-9 [3012536.001]
  • [Cites] Lab Invest. 2005 Jan;85(1):24-33 [15608663.001]
  • (PMID = 16884328.001).
  • [ISSN] 1177-1062
  • [Journal-full-title] Molecular diagnosis & therapy
  • [ISO-abbreviation] Mol Diagn Ther
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] New Zealand
  • [Chemical-registry-number] EC 2.3.2.27 / Von Hippel-Lindau Tumor Suppressor Protein; EC 6.3.2.- / VHL protein, human
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6. Navas-García M, Pedrosa-Sánchez M, Carrasco-Moro R, Pascual-Garvi JM, Sola RG: [Cystic hemangioblastoma of the junction of the medulla and upper spinal cord associated to von Hippel-Lindau disease. Two case reports and a review of the literature]. Rev Neurol; 2009 May 1-15;48(9):463-8
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  • [Title] [Cystic hemangioblastoma of the junction of the medulla and upper spinal cord associated to von Hippel-Lindau disease. Two case reports and a review of the literature].
  • [Transliterated title] Hemangioblastoma quistico de la union bulbomedular asociado a enfermedad de von Hippel-Lindau. Presentacion de dos casos y revision de la bibliografia.
  • INTRODUCTION: Hemangioblastomas are very highly vascularised benign tumours that can present either sporadically or in association with von Hippel-Lindau syndrome in 20% of cases.
  • Only 5-20% of hemangioblastomas are located in the brainstem, and those that occur at the junction of the medulla and upper spinal cord are the ones that are less commonly diagnosed.
  • CASE REPORTS: Two young patients were diagnosed with von Hippel-Lindau disease after beginning with a cystic hemangioblastoma at the junction of the medulla and upper spinal cord as the first pathological manifestation.
  • One of the patients required a reintervention some years later due to a new recurrence of a symptomatic hemangioblastoma in the dorsal medulla.
  • The genetic study conducted in both patients confirmed the presence of a mutation in the VHL gene, which is responsible for the syndrome they were suffering from.
  • CONCLUSIONS: The presence of cystic hemangioblastomas of the junction of the medulla and upper spinal cord associated to von Hippel-Lindau disease is very rare.
  • [MeSH-major] Cysts / pathology. Hemangioblastoma. Medulla Oblongata. Spinal Cord. von Hippel-Lindau Disease / pathology. von Hippel-Lindau Disease / surgery

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  • (PMID = 19396763.001).
  • [ISSN] 1576-6578
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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7. Ordóñez NG: Podoplanin: a novel diagnostic immunohistochemical marker. Adv Anat Pathol; 2006 Mar;13(2):83-8
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  • Podoplanin has also been shown to be strongly expressed in seminomas, epithelioid mesotheliomas, and hemangioblastomas, and immunostaining for this marker can assist in the diagnosis of these tumors.

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  • (PMID = 16670463.001).
  • [ISSN] 1072-4109
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Biomarkers, Tumor; 0 / Membrane Glycoproteins; 0 / PDPN protein, human; 0 / monoclonal antibody D2-40
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8. Bastos-Carvalho A, Damato B: Images in clinical medicine. Retinal hemangioblastoma in von Hippel-Lindau disease. N Engl J Med; 2010 Aug 12;363(7):663
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  • [Title] Images in clinical medicine. Retinal hemangioblastoma in von Hippel-Lindau disease.
  • [MeSH-major] Hemangioblastoma / etiology. Retinal Neoplasms / etiology. von Hippel-Lindau Disease / complications
  • [MeSH-minor] Adolescent. Female. Humans. Retina / pathology. Vision Disorders / etiology. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 20818857.001).
  • [ISSN] 1533-4406
  • [Journal-full-title] The New England journal of medicine
  • [ISO-abbreviation] N. Engl. J. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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9. Hakyemez B, Erdogan C, Bolca N, Yildirim N, Gokalp G, Parlak M: Evaluation of different cerebral mass lesions by perfusion-weighted MR imaging. J Magn Reson Imaging; 2006 Oct;24(4):817-24
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  • MATERIALS AND METHODS: This study involved 105 patients with lesions (high-grade glioma (N=26), low-grade glioma (N=11), meningioma (N=23), metastasis (N=25), hemangioblastoma (N=6), pyogenic abscess (N=4), schwannoma (N=5), and lymphoma (N=5)).
  • A P-value less than 0.05 was considered statistically significant.
  • RESULTS: The rCBV ratio was 5.76+/-3.35 in high-grade gliomas, 1.69+/-0.51 in low-grade gliomas, 8.02+/-3.89 in meningiomas, 5.27+/-3.22 in metastases, 11.36+/-4.41 in hemangioblastomas, 0.76+/-0.12 in abscesses, 1.10+/-0.32 in lymphomas, and 3.23+/-0.81 in schwannomas.
  • The rCBV ratios were used to discriminate between 1) high- and low-grade gliomas (P<0.001), 2) hemangioblastomas and metastases (P<0.05), 3) abscesses from high-grade gliomas and metastases (P<0.001), 4) schwannomas and meningiomas (P<0.001), 5) lymphomas from high-grade gliomas and metastases (P<0.001), and 6) typical meningiomas and atypical meningiomas (P<0.01).
  • It is possible to discriminate between 1) high- and low-grade gliomas, 2) hemangioblastomas and other intracranial posterior fossa masses, 3) abscesses from high-grade gliomas and metastases, 4) schwannomas and meningiomas, 5) lymphomas and high-grade gliomas and metastases, and 6) typical and atypical meningiomas.

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  • [Copyright] Copyright (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16958061.001).
  • [ISSN] 1053-1807
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Franke G, Bausch B, Hoffmann MM, Cybulla M, Wilhelm C, Kohlhase J, Scherer G, Neumann HP: Alu-Alu recombination underlies the vast majority of large VHL germline deletions: Molecular characterization and genotype-phenotype correlations in VHL patients. Hum Mutat; 2009 May;30(5):776-86
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  • Von Hippel-Lindau disease (VHL) is an autosomal dominant cancer syndrome.
  • In comparison to VHL patients in general, the 54 index cases and their affected relatives showed a higher occurrence of renal cell carcinomas (RCC) and of CNS hemangioblastomas.
  • We not only noted the association of RCC with retention of the HSPC300 gene, but also observed a significant correlation between retention of HSPC300 and the development of retinal angiomas (AR).
  • [MeSH-major] Alu Elements / genetics. Germ-Line Mutation / genetics. Recombination, Genetic / genetics. Sequence Deletion / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics

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  • [Copyright] Copyright 2009 Wiley-Liss, Inc.
  • [CommentIn] Hum Mutat. 2009 Sep;30(9):1365-6; author reply 1367 [19623534.001]
  • (PMID = 19280651.001).
  • [ISSN] 1098-1004
  • [Journal-full-title] Human mutation
  • [ISO-abbreviation] Hum. Mutat.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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11. Drabko K, Choma M, Zaucha-Prazmo A, Wójcik B, Gorczyńska E, Kałwak K, Turkiewicz D, Słociak M, Ussowicz M, Dyla A, Chybicka A, Styczyński J, Debski R, Wysocki M, Goździk J, Ratajczak M, Kowalczyk JR: [Megachemotherapy and autologous hematopoietic stem cell transplantation in children with solid tumours excluding neuroblastoma--experience of Polish paediatric centres]. Med Wieku Rozwoj; 2006 Jul-Sep;10(3 Pt 1):785-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 25 children were treated for Ewing Sarcoma, 13 for rhabdomyosarcoma embryonale (RMS), 7 for germinal tumours, 6 for medulloblastoma, 4 for PNET, 4 for Wilm's tumours, 2 for glioblastoma and single patients with mesenchymoma, astrocytoma, ependymoma, angioblastoma, carcinoma ovarian and carcinoma embryonale glutei.
  • RESULTS: 30 children are alive (44%), 28 of them in complete remission of disease.
  • 39 patients relapsed at a median time 11 months after MCT and 37 of them subsequently died of disease at a median time of 16 months.
  • One toxic death was noted--it was a boy, transplanted with progressive disease.
  • [MeSH-minor] Academic Medical Centers. Adolescent. Antineoplastic Agents, Alkylating / administration & dosage. Bone Neoplasms / drug therapy. Bone Neoplasms / surgery. Child. Child, Preschool. Combined Modality Therapy. Disease-Free Survival. Dose-Response Relationship, Drug. Ependymoma / drug therapy. Ependymoma / surgery. Female. Glioblastoma / drug therapy. Glioblastoma / surgery. Glioma / drug therapy. Glioma / surgery. Humans. Infant. Male. Meningeal Neoplasms / drug therapy. Meningeal Neoplasms / surgery. Meningioma / drug therapy. Meningioma / surgery. Neoplasm Staging. Oncology Service, Hospital. Poland. Remission Induction. Retrospective Studies. Sarcoma, Ewing / drug therapy. Sarcoma, Ewing / surgery. Transplantation, Autologous. Treatment Outcome


12. Longatti P, Basaldella L, Orvieto E, Dei Tos AP, Martinuzzi A: Aquaporin 1 expression in cystic hemangioblastomas. Neurosci Lett; 2006 Jan 16;392(3):178-80
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  • [Title] Aquaporin 1 expression in cystic hemangioblastomas.
  • Hemangioblastomas of the central nervous system (CNS) become clinically manifest through the development of huge associated cysts.
  • We analyzed AQP1 water channel expression by an immunostaining technique in ten specimens of operated cerebellar cystic hemangioblastomas, for which complete clinical and follow-up records were available.
  • Heavy AQP1 expression in cystic hemangioblastomas could shed new light on the mechanisms of satellite cyst development.
  • [MeSH-major] Aquaporin 1 / metabolism. Cerebellar Neoplasms / metabolism. Cysts. Gene Expression Regulation, Neoplastic / physiology. Hemangioblastoma / metabolism

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  • (PMID = 16300893.001).
  • [ISSN] 0304-3940
  • [Journal-full-title] Neuroscience letters
  • [ISO-abbreviation] Neurosci. Lett.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 146410-94-8 / Aquaporin 1
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13. Sun X, Liu M, Wei Y, Liu F, Zhi X, Xu R, Krissansen GW: Overexpression of von Hippel-Lindau tumor suppressor protein and antisense HIF-1alpha eradicates gliomas. Cancer Gene Ther; 2006 Apr;13(4):428-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Overexpression of von Hippel-Lindau tumor suppressor protein and antisense HIF-1alpha eradicates gliomas.
  • The von Hippel-Lindau tumor suppressor protein (pVHL) suppresses tumor formation by binding the alpha subunits of hypoxia-inducible-factors responsible for stimulating tumor angiogenesis and glycolysis, and targeting them for ubiquitination and proteasomal destruction.
  • Loss of pVHL leads to tumorigenesis and development of sporadic renal cell carcinomas and central nervous system hemangioblastomas.
  • [MeSH-major] Glioma / metabolism. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 16211089.001).
  • [ISSN] 0929-1903
  • [Journal-full-title] Cancer gene therapy
  • [ISO-abbreviation] Cancer Gene Ther.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Antisense; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Vascular Endothelial Growth Factor A; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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14. Valenzuela A, Druker H, Malkin D, Gallie B, Héon E: Unusual ocular presentation of von Hippel-Lindau disease. Can J Ophthalmol; 2005 Oct;40(5):593-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual ocular presentation of von Hippel-Lindau disease.
  • CASE REPORT: We report a young girl who first presented with a unilateral total exudative retinal detachment diagnosed as Coats' disease.
  • Eight years later, when she presented with classical retinal hemangioblastomas with reduced vision in the fellow eye, the diagnosis of von Hippel-Lindau (VHL) disease was confirmed.
  • COMMENTS: This case highlights the importance of considering the possibility of VHL in atypical cases of Coats' disease and unusual sporadic cases of unexplained unilateral exudative retinal detachment.
  • The identification of VHL mutations and subsequent screening allows early diagnosis and treatment of asymptomatic retinal or central nervous system hemangioblastomas, as well as other malignancies associated with this syndrome.

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  • (PMID = 16391622.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / RNA, Messenger; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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15. Alexiou GA, Tsiouris S, Polyzoidis KS, Fotopoulos AD, Kyritsis AP: Re: Delayed diagnosis of cerebellar hemangioblastoma after intracerebellar hemorrhage (Lee et al Surg Neurol 2007;67:419-421) Technetium (99m)Tc tetrofosmin brain single-photon emission computed tomography in the evaluation of posterior fossa lesions. Surg Neurol; 2008 Jul;70(1):108-9
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  • [Title] Re: Delayed diagnosis of cerebellar hemangioblastoma after intracerebellar hemorrhage (Lee et al Surg Neurol 2007;67:419-421) Technetium (99m)Tc tetrofosmin brain single-photon emission computed tomography in the evaluation of posterior fossa lesions.
  • [MeSH-major] Cerebellar Neoplasms / radionuclide imaging. Hemangioblastoma / radionuclide imaging. Intracranial Hemorrhages / etiology. Organophosphorus Compounds. Organotechnetium Compounds. Radiopharmaceuticals. Tomography, Emission-Computed, Single-Photon

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  • [CommentOn] Surg Neurol. 2007 Apr;67(4):419-21 [17350421.001]
  • (PMID = 18313731.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Organophosphorus Compounds; 0 / Organotechnetium Compounds; 0 / Radiopharmaceuticals; 0 / technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane
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16. Iplikcioglu AC, Hatiboglu MA, Ozek E, Dinc C, Erdal M: Surgical removal of spinal mass lesions with open door laminoplasty. Cent Eur Neurosurg; 2010 Nov;71(4):213-8
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  • The histological diagnoses were 4 astrocytomas, 2 meningiomas, 3 neurinomas, 2 ependymomas and one case each with Ewing's sarcoma, metastasis, abcess, hemangioblastoma, arachnoid cyst and lipoma.

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  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 20458672.001).
  • [ISSN] 1868-4912
  • [Journal-full-title] Central European neurosurgery
  • [ISO-abbreviation] Cent Eur Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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17. Di X: Multiple brain tumor nodule resections under direct visualization of a neuronavigated endoscope. Minim Invasive Neurosurg; 2007 Aug;50(4):227-32
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  • [Title] Multiple brain tumor nodule resections under direct visualization of a neuronavigated endoscope.
  • METHODS: A 0-degree, 4-mm rigid endoscopes (DCI; Storz and Co., Tuttlingen, Germany) and Voyager SX navigation system by Z-KAT (Marconi, USA) were used for both cases, a 32-year-old woman with multiple hemangioblastomas and a 46-year-old man with two recurrent astrocytomas.
  • RESULTS: A 3-cm linear skin incision for both cases was made at the entry point guided by the endoscope's video output and a 3-dimensional (3-D) rendered image on the navigation system.
  • [MeSH-minor] Adult. Astrocytoma / pathology. Astrocytoma / surgery. Cerebellum / pathology. Cerebellum / physiopathology. Cerebellum / surgery. Endoscopes / standards. Female. Hemangioblastoma / pathology. Hemangioblastoma / surgery. Humans. Male. Middle Aged. Minimally Invasive Surgical Procedures / instrumentation. Minimally Invasive Surgical Procedures / methods. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / prevention & control. Neoplasm Recurrence, Local / surgery. Treatment Outcome

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  • (PMID = 17948182.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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18. Wu YM, Wong HF, Ng SH: Direct Intratumoral Pre-surgical Embolization of Orbital Hemangioblastoma. A Case Report. Neuroradiol J; 2008 Dec 17;21(5):693-7
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  • [Title] Direct Intratumoral Pre-surgical Embolization of Orbital Hemangioblastoma. A Case Report.
  • Orbital hemangioblastomas of extraretinal origin are extremely rare and few cases have been reported.
  • We describe a 48-year-old woman with progressive right visual loss and proptosis.
  • The histopathologic characteristics of this tumor were identical to those seen in central nervous system hemangioblastomas.

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  • (PMID = 24257013.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Martin SE, Al-Khatib SM, Turner MS, Douglas-Akinwande AC, Hattab EM: A 41-year-old woman with von Hippel-Lindau and a cerebellar lesion. Brain Pathol; 2010 Mar;20(2):511-4
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  • [Title] A 41-year-old woman with von Hippel-Lindau and a cerebellar lesion.
  • A 41-year-old woman with a 12-year history of von Hippel-Lindau disease presented with progressive quadriparesis and difficulty swallowing.
  • MRI revealed a well-circumscribed, partially cystic cerebellar neoplasm, consistent with hemangioblastoma.
  • The tumor was resected and the diagnosis of hemangioblastoma confirmed.
  • Embedded within the hemangioblastoma was a small focus of metastatic renal cell carcinoma (RCC).
  • RCC metastatic to a CNS hemangioblastoma is the second most common type of tumor-to-tumor metastasis, which may be due to a number of factors.
  • [MeSH-major] Carcinoma, Renal Cell / secondary. Cerebellar Neoplasms / pathology. Hemangioblastoma / pathology. von Hippel-Lindau Disease / pathology

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  • (PMID = 20438472.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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20. Kim HR, Suh YL, Kim JW, Lee JI: Disseminated hemangioblastomatosis of the central nervous system without von Hippel-Lindau disease: a case report. J Korean Med Sci; 2009 Aug;24(4):755-9
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  • [Title] Disseminated hemangioblastomatosis of the central nervous system without von Hippel-Lindau disease: a case report.
  • We report a very rare case of hemangioblastomatosis that developed after surgical removal of a solitary cerebellar hemangioblastoma (HB).
  • Genomic DNA analysis showed no mutation in the von Hippel-Lindau (VHL) genes.
  • [MeSH-major] Central Nervous System Neoplasms / diagnosis. Hemangioblastoma / diagnosis
  • [MeSH-minor] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / radiotherapy. Cerebellar Neoplasms / surgery. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Recurrence. von Hippel-Lindau Disease / genetics

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  • [Cites] Acta Neurochir (Wien). 1999;141(11):1147-56 [10592114.001]
  • [Cites] J Neurooncol. 2007 Apr;82(2):163-4 [17256106.001]
  • [Cites] Gastroenterology. 2000 Oct;119(4):1087-95 [11040195.001]
  • [Cites] Clin Cancer Res. 2001 Mar;7(3):510-6 [11297241.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2001 May;70(5):644-8 [11309459.001]
  • [Cites] J Neurosurg. 2002 Apr;96(4):775-87 [11990821.001]
  • [Cites] Neurosurgery. 2003 May;52(5):1212-5; discussion 1215-6 [12699568.001]
  • [Cites] Lancet. 2003 Jun 14;361(9374):2059-67 [12814730.001]
  • [Cites] Am J Ophthalmol. 2003 Jul;136(1):194-6 [12834696.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1976 Jun;39(6):515-25 [1084914.001]
  • [Cites] Acta Neurochir (Wien). 1978;44(1-2):107-13 [569422.001]
  • [Cites] J Neurosurg. 1989 Jan;70(1):24-30 [2909683.001]
  • [Cites] No Shinkei Geka. 1990 Jan;18(1):83-8 [2304611.001]
  • [Cites] Radiology. 1990 Mar;174(3 Pt 1):815-20 [2305064.001]
  • [Cites] AJR Am J Roentgenol. 1994 May;162(5):1091-4 [8165988.001]
  • [Cites] Radiology. 1995 Mar;194(3):629-42 [7862955.001]
  • [Cites] J Neuroimaging. 1997 Oct;7(4):242-4 [9344008.001]
  • [Cites] Cancer Res. 1998 Feb 1;58(3):504-8 [9458097.001]
  • [Cites] N Engl J Med. 1999 Jun 17;340(24):1872-9 [10369850.001]
  • [Cites] J Neurooncol. 2005 May;72(3):267-70 [15937651.001]
  • [Cites] Neurosurg Rev. 2000 Mar;23(1):1-22; discussion 23-4 [10809480.001]
  • (PMID = 19654966.001).
  • [ISSN] 1598-6357
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2719216
  • [Keywords] NOTNLM ; Central Nervous System / Hemangioblastoma / von Hippel-Lindau Disease
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21. Rao S, Rajkumar A, Kuruvilla S: Angiomatous meningioma: a diagnostic dilemma. Indian J Pathol Microbiol; 2008 Jan-Mar;51(1):53-5
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  • It has features of a typical benign meningioma with many small or large vascular channels which may predominate over its meningothelial elements.
  • We present series of three cases to highlight the histomorphological features of this uncommon variant of meningioma that could help in distinguishing it from hemangioblastoma and hemangiopericytoma.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Hemangioblastoma / diagnosis. Hemangiopericytoma / diagnosis. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18417856.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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22. Taylor KL, Oates RK, Grane R, Leaman DW, Borden EC, Lindner DJ: IFN-alpha1,8 inhibits tumor-induced angiogenesis in murine angiosarcomas. J Interferon Cytokine Res; 2006 May;26(5):353-61
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  • Interferon-alpha (IFN-alpha) has proved effective in the treatment of hemangiomas, hemangioblastomas, and Kaposi's sarcoma.
  • [MeSH-minor] Animals. Cell Line, Tumor. Cell Proliferation / drug effects. Chemokine CXCL10. Chemokines, CXC / biosynthesis. Chemokines, CXC / blood. Disease Progression. Humans. Mice. Xenograft Model Antitumor Assays

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  • (PMID = 16689662.001).
  • [ISSN] 1079-9907
  • [Journal-full-title] Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
  • [ISO-abbreviation] J. Interferon Cytokine Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01CA089344-04
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chemokine CXCL10; 0 / Chemokines, CXC; 0 / Interferon-alpha
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23. McAleer MA, Kirby B, Sheahan K, Collins P: An erythematous patch and plaque on the shoulder--quiz case. Acquired tufted angioma (TA). Arch Dermatol; 2008 Sep;144(9):1217-22
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  • [Title] An erythematous patch and plaque on the shoulder--quiz case. Acquired tufted angioma (TA).
  • [MeSH-major] Hemangioma / pathology. Shoulder. Skin Neoplasms / pathology


24. Masunaga K, Inadome A, Sugiyama Y, Maeda Y, Satoji Y, Takahashi W, Yoshida M, Ueda S, Ikeda K, Takano Y, Yatsuda J: [Bilateral pheochromocytomas with von Hippel-Lindau disease: a case report]. Nihon Hinyokika Gakkai Zasshi; 2007 Nov;98(7):843-7
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  • [Title] [Bilateral pheochromocytomas with von Hippel-Lindau disease: a case report].
  • A case of bilateral pheochromocytomas with von Hippel Lindau disease (VHL) is reported.
  • Moreover, he had cerebellar and spinal hemangioblastomas.
  • His sister had been diagnosed as VHL disease.
  • We diagnosed the patient as VHL disease because of the existence of cerebellar and spinal hemangioblastomas, bilateral pheochromocytomas, missense mutation and his family history.
  • This is the eleventh case of bilateral pheochromocytomas with VHL disease reported in Japanese literatures.
  • [MeSH-major] Adrenal Gland Neoplasms / complications. Adrenal Gland Neoplasms / diagnosis. Pheochromocytoma / complications. von Hippel-Lindau Disease / complications. von Hippel-Lindau Disease / diagnosis

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  • (PMID = 18062217.001).
  • [ISSN] 0021-5287
  • [Journal-full-title] Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
  • [ISO-abbreviation] Nippon Hinyokika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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25. Chew EY: Ocular manifestations of von Hippel-Lindau disease: clinical and genetic investigations. Trans Am Ophthalmol Soc; 2005;103:495-511
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  • [Title] Ocular manifestations of von Hippel-Lindau disease: clinical and genetic investigations.
  • PURPOSE: To describe the clinical spectrum of lesions involving the visual system in von Hippel-Lindau (VHL) disease, the genetic alterations, and the molecular genetic properties of retinal hemangioblastomas.
  • METHODS: In this prospective case-series, 406 patients with VHL disease had systemic and ocular evaluations.
  • RESULTS: Half of the 406 patients (199 families) with VHL disease had ocular involvement.
  • Visual acuity was 20/20 or better in 170 patients (84.5%) with hemangioblastomas; six (3%) were legally blind.
  • The patients with complete deletion were less likely to have ocular VHL compared with those patients with partial deletion, missense, and nonsense mutation (9% versus 45%) (P < .0001), suggesting the importance of the gene or areas of genes on chromosome 3 for the development of retinal hemangioblastomas.
  • CONCLUSIONS: In this series, the largest of its kind, patients with ocular lesions of VHL disease are referred mostly from physicians.
  • [MeSH-major] Hemangioblastoma / etiology. Retinal Neoplasms / etiology. von Hippel-Lindau Disease / complications

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  • [Cites] Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1977 May-Jun;83(3 Pt 1):OP446-53 [888257.001]
  • [Cites] Ophthalmology. 2002 Oct;109(10):1799-806 [12359597.001]
  • [Cites] Ophthalmology. 2000 Jan;107(1):48-54 [10647718.001]
  • [Cites] Eur J Med Res. 2000 Feb 28;5(2):47-58 [10720563.001]
  • [Cites] Neurosurg Rev. 2000 Mar;23(1):1-22; discussion 23-4 [10809480.001]
  • [Cites] Gastroenterology. 2000 Oct;119(4):1087-95 [11040195.001]
  • [Cites] Surv Ophthalmol. 2001 Sep-Oct;46(2):117-42 [11578646.001]
  • [Cites] Arch Ophthalmol. 2002 Mar;120(3):338-46 [11879138.001]
  • [Cites] Cancer Cell. 2002 Apr;1(3):237-46 [12086860.001]
  • [Cites] Ophthalmology. 2002 Jul;109(7):1256-66 [12093647.001]
  • [Cites] Invest Ophthalmol Vis Sci. 2002 Sep;43(9):3067-74 [12202531.001]
  • [Cites] Nat Rev Cancer. 2002 Sep;2(9):673-82 [12209156.001]
  • [Cites] Ophthalmology. 2002 Sep;109(9):1745-51 [12208726.001]
  • [Cites] Clin Imaging. 2003 Jan-Feb;27(1):18-22 [12504315.001]
  • [Cites] J Neurosurg. 2003 Jan;98(1):82-94 [12546356.001]
  • [Cites] Ophthalmology. 2003 May;110(5):979-86 [12750101.001]
  • [Cites] Lancet. 2003 Jun 14;361(9374):2059-67 [12814730.001]
  • [Cites] Am J Ophthalmol. 2003 Jul;136(1):194-6 [12834696.001]
  • [Cites] Cancer Res. 2003 Nov 1;63(21):7051-5 [14612494.001]
  • [Cites] Hum Mutat. 2004 Jan;23(1):40-6 [14695531.001]
  • [Cites] Trans Am Ophthalmol Soc. 1970;68:367-424 [5535648.001]
  • [Cites] Am J Hum Genet. 1972 Sep;24(5):514-32 [4340974.001]
  • [Cites] Int Ophthalmol Clin. 1972 Spring;12(1):1-50 [4630193.001]
  • [Cites] Cancer. 1976 Nov;38(5):2042-56 [1033029.001]
  • [Cites] Clin Radiol. 1981 Jul;32(4):389-92 [7195787.001]
  • [Cites] J Neurosurg. 1982 Mar;56(3):426-9 [7199079.001]
  • [Cites] Ophthalmology. 1983 Jul;90(7):848-55 [6353309.001]
  • [Cites] Can J Ophthalmol. 1986 Dec;21(7):276-83 [3801976.001]
  • [Cites] Annu Rev Genet. 1986;20:231-51 [2880556.001]
  • [Cites] Retina. 1986 Winter;6(4):253-9 [3554423.001]
  • [Cites] Nature. 1988 Mar 17;332(6161):268-9 [2894613.001]
  • [Cites] Ophthalmology. 1988 Mar;95(3):398-402 [3050687.001]
  • [Cites] Medicine (Baltimore). 1989 Jan;68(1):1-29 [2642584.001]
  • [Cites] Q J Med. 1990 Nov;77(283):1151-63 [2274658.001]
  • [Cites] Lancet. 1991 May 4;337(8749):1052-4 [1673491.001]
  • [Cites] J Med Genet. 1991 Jul;28(7):443-7 [1895313.001]
  • [Cites] Ophthalmology. 1992 Jan;99(1):140-5 [1741127.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1992 Oct;55(10):898-901 [1431953.001]
  • [Cites] Science. 1993 May 28;260(5112):1317-20 [8493574.001]
  • [Cites] Hum Pathol. 1994 Nov;25(11):1249-51 [7959672.001]
  • [Cites] JAMA. 1995 Feb 15;273(7):564-70 [7837390.001]
  • [Cites] Neurosurgery. 1995 Mar;36(3):573-80; discussion 580-1 [7753357.001]
  • [Cites] Am J Pathol. 1995 Aug;147(2):245-50 [7639324.001]
  • [Cites] Science. 1995 Sep 8;269(5229):1402-6 [7660122.001]
  • [Cites] Ophthalmology. 1996 Feb;103(2):329-35 ; discussion 334-5 [8594522.001]
  • [Cites] J Neuropathol Exp Neurol. 1996 May;55(5):522-7 [8627342.001]
  • [Cites] Retina. 1996;16(2):145-56 [8724960.001]
  • [Cites] Am J Pathol. 1996 Dec;149(6):2089-94 [8952541.001]
  • [Cites] Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2156-61 [9122164.001]
  • [Cites] Am J Respir Cell Mol Biol. 1997 Apr;16(4):398-406 [9115750.001]
  • [Cites] Hum Pathol. 1997 May;28(5):540-3 [9158701.001]
  • [Cites] Diabetes. 1997 Sep;46(9):1473-80 [9287049.001]
  • [Cites] Medicine (Baltimore). 1997 Nov;76(6):381-91 [9413424.001]
  • [Cites] Int Ophthalmol Clin. 1997 Fall;37(4):159-70 [9429939.001]
  • [Cites] Eur J Pharmacol. 1998 Jan 12;341(2-3):309-15 [9543253.001]
  • [Cites] J Intern Med. 1998 Jun;243(6):547-53 [9681857.001]
  • [Cites] Nature. 1998 Jul 30;394(6692):485-90 [9697772.001]
  • [Cites] Arch Ophthalmol. 1999 Mar;117(3):371-8 [10088816.001]
  • [Cites] Arch Ophthalmol. 1999 May;117(5):625-30 [10326959.001]
  • [Cites] Nature. 1999 May 20;399(6733):271-5 [10353251.001]
  • [Cites] Am J Med. 1964 Apr;36:595-617 [14142412.001]
  • [Cites] Ann Ophthalmol. 1981 Feb;13(2):195-7 [7195679.001]
  • (PMID = 17057815.001).
  • [ISSN] 1545-6110
  • [Journal-full-title] Transactions of the American Ophthalmological Society
  • [ISO-abbreviation] Trans Am Ophthalmol Soc
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z99 EY999999
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1447586
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26. Sun H, Zhao JZ: Application of intraoperative ultrasound in neurological surgery. Minim Invasive Neurosurg; 2007 Jun;50(3):155-9
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  • PATIENTS AND METHODS: IOUS was applied in 110 operations, involving 68 gliomas, 7 meningiomas, 1 acoustic neuroma, 5 hemangioblastomas, 3 granulomas, 17 AVMs and 9 cavernous angiomas.

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  • (PMID = 17882751.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Germany
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27. Vogel TW, Vortmeyer AO, Lubensky IA, Lee YS, Furuta M, Ikejiri B, Kim HJ, Lonser RR, Oldfield EH, Zhuang Z: Coexpression of erythropoietin and its receptor in endolymphatic sac tumors. J Neurosurg; 2005 Aug;103(2):284-8
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  • OBJECT: Von Hippel-Lindau (VHL) disease is characterized by multiple tumors in specific organs.
  • Endolymphatic sac tumor (ELST) is one of the lesions associated with VHL disease.
  • Data from previous studies of VHL disease-associated hemangioblastomas (HBs) and renal cell carcinomas (RCCs) have indicated that VHL gene deficiency causes coexpression of erythropoietin (Epo) and its receptor (Epo-R), which facilitates tumor growth.
  • Coexpression of Epo and Epo-R in ELSTs together with the morphological and genetic similarities of these lesions with other VHL disease-associated tumors indicates that VHL disease-associated tumors in different organs share common pathogenetic pathways.
  • [MeSH-minor] Adult. Gene Expression Profiling. Germ-Line Mutation. Humans. Immunohistochemistry. Male. Reverse Transcriptase Polymerase Chain Reaction. von Hippel-Lindau Disease

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  • (PMID = 16175858.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Erythropoietin; 11096-26-7 / Erythropoietin
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28. Ercolino T, Becherini L, Valeri A, Maiello M, Gaglianò MS, Parenti G, Ramazzotti M, Piscitelli E, Simi L, Pinzani P, Nesi G, Degl'Innocenti D, Console N, Bergamini C, Mannelli M: Uncommon clinical presentations of pheochromocytoma and paraganglioma in two different patients affected by two distinct novel VHL germline mutations. Clin Endocrinol (Oxf); 2008 May;68(5):762-8
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  • CONTEXT: The von Hippel-Lindau (VHL) syndrome is an inherited multitumour disorder characterized by clinical heterogeneity and high penetrance.
  • Pheochromocytoma (Pheo) is present in 10%-15% of cases and can be isolated or associated with other lesions such as haemangioblastomas, kidney cysts or cancer and pancreatic lesions.
  • One patient was studied for the presence of an adrenal incidentaloma and the other for the presence of a neck tumour.
  • CONCLUSIONS: These cases enlarge the list of VHL mutations and add new insights in the clinical variability of VHL disease, thus confirming the importance of genetic testing in patients affected by apparently sporadic Pheos or PGLs.
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Head and Neck Neoplasms / genetics. Paraganglioma / genetics. Pheochromocytoma / genetics. von Hippel-Lindau Disease / genetics


29. Isobe T, Yamamoto T, Akutsu H, Anno I, Shiigai M, Zaboronok A, Masumoto T, Takano S, Matsumura A: Proton magnetic resonance spectroscopy findings of hemangioblastoma. Jpn J Radiol; 2010 May;28(4):318-21
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  • [Title] Proton magnetic resonance spectroscopy findings of hemangioblastoma.
  • We report a case of proton magnetic resonance spectroscopy (MRS) of hemangioblastoma in a 56-yearold man with a history of hyperlipidemia who was suffering from an equilibrium disorder.
  • Combined with the absence of the necrotic component on magnetic resonance imaging, this Lip peak on proton MRS could be the characteristic pattern of hemangioblastoma.
  • These unique results of proton MRS can play an important role in the differential diagnosis of intracranial hemangioblastoma.
  • However, further investigations are required to establish the typical characteristics of proton MRS of hemangioblastoma.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Hemangioblastoma / diagnosis. Magnetic Resonance Spectroscopy / methods

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  • [Cites] J Neurol. 1996 Oct;243(10):706-14 [8923303.001]
  • [Cites] Igaku Butsuri. 2005;25(2):68-74 [16135894.001]
  • [Cites] Cancer. 1978 Oct;42(4):1834-50 [361212.001]
  • [Cites] Chin Med J (Engl). 2008 Dec 5;121(23):2415-9 [19102960.001]
  • [Cites] NMR Biomed. 1991 Apr;4(2):99-102 [1859788.001]
  • [Cites] NMR Biomed. 1991 Apr;4(2):47-52 [1650241.001]
  • [Cites] Hum Pathol. 1997 May;28(5):540-3 [9158701.001]
  • [Cites] Neurosurg Rev. 2002 Mar;25(1-2):107-9 [11954763.001]
  • [Cites] Magn Reson Med. 1989 Jan;9(1):79-93 [2540396.001]
  • [Cites] Magn Reson Imaging. 2003 Jul;21(6):663-72 [12915198.001]
  • (PMID = 20512552.001).
  • [ISSN] 1867-108X
  • [Journal-full-title] Japanese journal of radiology
  • [ISO-abbreviation] Jpn J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Protons
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30. Lonser RR, Butman JA, Kiringoda R, Song D, Oldfield EH: Pituitary stalk hemangioblastomas in von Hippel-Lindau disease. J Neurosurg; 2009 Feb;110(2):350-3
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  • [Title] Pituitary stalk hemangioblastomas in von Hippel-Lindau disease.
  • OBJECT: Pituitary stalk hemangioblastomas are rare, and information on them is limited to a small number of case reports.
  • To gain insight into the incidence, clinical effects, and management of pituitary stalk hemangioblastomas, the authors analyzed a series of patients with von Hippel-Lindau (VHL) disease.
  • METHODS: Patients with VHL disease who were enrolled in a prospective National Institutes of Health natural history study were included.
  • In 8 patients (3%), 8 pituitary stalk hemangioblastomas were identified on MR imaging.
  • This anatomical location was the most common supratentorial site for these lesions; 29% of all supratentorial hemangioblastomas were found there.
  • The mean (+/- standard deviation) pituitary stalk hemangioblastoma volume was 0.5 +/- 0.9 cm(3) (range 0.08-2.8 cm(3)).
  • CONCLUSIONS: The pituitary stalk is the most common site for the development of supratentorial hemangioblastomas in patients with VHL disease.
  • Pituitary stalk hemangioblastomas often remain asymptomatic and do not require treatment.
  • These findings indicate that pituitary stalk hemangioblastomas in patients with VHL disease may be managed with observation and that surgery for them can be reserved until associated signs or symptoms occur.
  • [MeSH-major] Hemangioblastoma / diagnosis. Image Enhancement. Magnetic Resonance Imaging. Pituitary Gland. Pituitary Neoplasms / diagnosis. Supratentorial Neoplasms / diagnosis. von Hippel-Lindau Disease / surgery

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  • [Cites] Clin Neurol Neurosurg. 2007 Apr;109(3):292-8 [17187928.001]
  • [Cites] J Clin Neurosci. 2005 Jan;12(1):85-9 [15639422.001]
  • [Cites] J Neurosurg. 2000 Jun;92(6):1028-35 [10839266.001]
  • [Cites] No Shinkei Geka. 2001 Jul;29(7):679-83 [11517511.001]
  • [Cites] Surg Neurol. 2001 Jul;56(1):22-6 [11546565.001]
  • [Cites] Clin Imaging. 2003 Jan-Feb;27(1):18-22 [12504315.001]
  • [Cites] J Neurosurg. 2003 Jan;98(1):82-94 [12546356.001]
  • [Cites] AJR Am J Roentgenol. 2003 May;180(5):1480-1 [12704075.001]
  • [Cites] Lancet. 2003 Jun 14;361(9374):2059-67 [12814730.001]
  • [Cites] Ann Neurol. 2004 Feb;55(2):236-40 [14755727.001]
  • [Cites] N Engl J Med. 2004 Jun 10;350(24):2481-6 [15190140.001]
  • [Cites] Can Med Assoc J. 1969 Aug 9;101(3):135-42 [5817389.001]
  • [Cites] J Neurosurg. 1975 Feb;42(2):232-5 [1167581.001]
  • [Cites] Arch Neurol. 1976 Jun;33(6):435-41 [945725.001]
  • [Cites] Surg Neurol. 1984 Sep;22(3):257-62 [6540482.001]
  • [Cites] J Neurosurg. 1989 Jan;70(1):24-30 [2909683.001]
  • [Cites] Q J Med. 1990 Nov;77(283):1151-63 [2274658.001]
  • [Cites] Science. 1993 May 28;260(5112):1317-20 [8493574.001]
  • [Cites] J Neurosurg. 1996 Jun;84(6):1046-50 [8847570.001]
  • [Cites] J Neurosurg. 1996 Oct;85(4):591-6 [8814161.001]
  • [Cites] JAMA. 1997 May 14;277(18):1461-6 [9145719.001]
  • [Cites] Hum Pathol. 1997 May;28(5):540-3 [9158701.001]
  • [Cites] Surg Neurol. 1998 Nov;50(5):461-3; discussion 463-4 [9842873.001]
  • [Cites] J Neurosurg. 1963 Mar;20:254-64 [14192106.001]
  • [Cites] JAMA. 2007 Jul 4;298(1):41-8 [17609489.001]
  • (PMID = 18834262.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 NS003053-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS152863; NLM/ PMC2770699
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31. Sid-Ahmed S, Seizeur R, Forlodou P, Dam-Hieu P, Quintin-Roue I, Person H, Besson G: [Dumbell hemangioblastoma of the eighth cervical nerve root]. Neurochirurgie; 2006 Dec;52(6):533-6
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  • [Title] [Dumbell hemangioblastoma of the eighth cervical nerve root].
  • [Transliterated title] Hémangioblastome "en sablier" de la huitième racine cervicale.
  • Hemangioblastomas involving cervical nerve roots are extremely rare.
  • We report the case of a 33-year-old man presenting with a 6-month history of upper limb pain.
  • MRI and cervical angiography demonstrated the presence of a dumbell (intra and extradural) and highly vascularized tumor of the right C7-T1 foramina.
  • Histological examination eventually confirmed the diagnosis of hemangioblastoma.
  • [MeSH-major] Cranial Nerve Neoplasms / surgery. Hemangioblastoma / surgery. Vestibulocochlear Nerve / pathology

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  • (PMID = 17203902.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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32. Bhatnagar AK, Gerszten PC, Ozhasaglu C, Vogel WJ, Kalnicki S, Welch WC, Burton SA: CyberKnife Frameless Radiosurgery for the treatment of extracranial benign tumors. Technol Cancer Res Treat; 2005 Oct;4(5):571-6
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  • Of these tumors, there were 21 neurofibromas, ten schwannomas, eight meningiomas, eight hemangioblastomas, seven paragangliomas, two hemangiopericytomas, one pseudotumor, one ependymoma, and one arteriovenous malformation (AVM).

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  • (PMID = 16173828.001).
  • [ISSN] 1533-0346
  • [Journal-full-title] Technology in cancer research & treatment
  • [ISO-abbreviation] Technol. Cancer Res. Treat.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Rodriguez V, Lee A, Witman PM, Anderson PA: Kasabach-merritt phenomenon: case series and retrospective review of the mayo clinic experience. J Pediatr Hematol Oncol; 2009 Jul;31(7):522-6
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  • Kasabach-Merritt phenomenon (KMP) is a rare thrombocytopenic consumption coagulopathy associated with an enlarging tufted angioma or kaposiform hemangioendothelioma.
  • [MeSH-major] Disseminated Intravascular Coagulation / complications. Disseminated Intravascular Coagulation / physiopathology. Hemangioendothelioma / complications. Hemangioma / complications. Skin Neoplasms / complications

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  • (PMID = 19564750.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Antineoplastic Agents
  • [Number-of-references] 10
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34. Xu QW, Xu R, Du ZY, Gao X: Surgical treatment for hemangioblastomas in the medulla oblongata. Acta Neurochir (Wien); 2010 Aug;152(8):1331-5; discussion 1335
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  • [Title] Surgical treatment for hemangioblastomas in the medulla oblongata.
  • PURPOSE: The purpose of this study was to evaluate the outcome of surgical treatment of hemangioblastomas in the medulla oblongata.
  • METHODS: Between January 2006 and December 2007, 18 patients who underwent surgery for hemangioblastomas in the medulla oblongata in the Neurosurgical Department of Huashan Hospital were retrospectively reviewed.
  • CONCLUSION: Surgery is the first-line treatment for symptomatic patients with hemangioblastomas in the medulla oblongata.
  • [MeSH-major] Brain Stem Neoplasms / surgery. Hemangioblastoma / surgery. Medulla Oblongata / surgery. Neurosurgical Procedures / methods

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  • (PMID = 20419458.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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35. Matsuyama M, Nakazawa K, Katou M, Ota K, Masuko H, Iizuka T, Mori T, Hayashi H, Hayashihara K, Saito T, Satoh M, Hizawa N: Central alveolar hypoventilation syndrome due to surgical resection for bulbar hemangioblastoma. Intern Med; 2009;48(11):925-30
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  • [Title] Central alveolar hypoventilation syndrome due to surgical resection for bulbar hemangioblastoma.
  • A 29-year-old man with a history of resected bulbar hemangioblastoma was admitted to hospital with nighttime breathing disturbance, but with apparently normal breathing while awake.
  • After diagnostic work-up, including polysomnographic testing, he was diagnosed as having central alveolar hypoventilation syndrome due to surgical resection for bulbar hemangioblastoma.
  • To the best of our knowledge, this is the first case report of central alveolar hypoventilation syndrome due to surgical resection for bulbar hemangioblastoma.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Hemangioblastoma / surgery. Sleep Disorders, Intrinsic / diagnosis. Sleep Disorders, Intrinsic / etiology

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  • (PMID = 19483363.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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36. Hue YH, Chun HJ, Yi HJ, Oh SH, Oh SJ, Ko Y: Unilateral posterior atlantoaxial transarticular screw fixation in patients with atlantoaxial instability : comparison with bilateral method. J Korean Neurosurg Soc; 2009 Mar;45(3):164-8
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  • The causes of unilateral TAF were anomalous course of vertebral artery in 20 patients (74%), severe degenerative arthritis in 3 (11%), fracture of C1 in 2, hemangioblastoma in one, and screw malposition in one.

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  • [Cites] J Spinal Disord Tech. 2007 Oct;20(7):499-504 [17912126.001]
  • [Cites] Spine (Phila Pa 1976). 2000 Jul 15;25(14):1760-4 [10888942.001]
  • [Cites] Eur Spine J. 2007 Apr;16(4):485-94 [17024400.001]
  • [Cites] Neurosurgery. 2007 Jan;60(1 Supp1 1):S103-11 [17204870.001]
  • [Cites] Spine (Phila Pa 1976). 2006 Jul 1;31(15):E513-7 [16816753.001]
  • [Cites] Neurosurg Rev. 2006 Apr;29(2):114-7 [16261392.001]
  • [Cites] Spine (Phila Pa 1976). 2005 Dec 15;30(24):2800-5 [16371908.001]
  • [Cites] Spine (Phila Pa 1976). 2005 May 1;30(9):E236-42 [15864141.001]
  • [Cites] J Neurosurg Spine. 2005 Feb;2(2):175-81 [15739530.001]
  • [Cites] J Neurosurg Spine. 2005 Feb;2(2):155-63 [15739527.001]
  • [Cites] J Long Term Eff Med Implants. 2005;15(1):33-8 [15715514.001]
  • [Cites] Spine (Phila Pa 1976). 1998 Aug 1;23(15):1703-7 [9704379.001]
  • [Cites] J Neurosurg. 1998 Apr;88(4):634-40 [9525707.001]
  • [Cites] J Neurosurg. 1997 Dec;87(6):851-5 [9384394.001]
  • [Cites] J Neurosurg. 1996 Aug;85(2):221-4 [8755749.001]
  • [Cites] J Neurosurg. 1993 Aug;79(2):234-7 [8331406.001]
  • [Cites] Spine (Phila Pa 1976). 1991 Oct;16(10):1141-5 [1754933.001]
  • [Cites] J Spinal Disord Tech. 2004 Apr;17(2):158-62 [15260101.001]
  • [Cites] Spine (Phila Pa 1976). 2003 Apr 1;28(7):666-70 [12671353.001]
  • [Cites] Neurosurgery. 2002 Dec;51(6):1351-6; discussion 1356-7 [12445339.001]
  • [Cites] Spine (Phila Pa 1976). 2001 Nov 15;26(22):2467-71 [11707712.001]
  • [Cites] Surg Neurol. 2001 Jan;55(1):29-33; discussion 33-4 [11248307.001]
  • [Cites] Spine (Phila Pa 1976). 2007 Jun 1;32(13):E363-70 [17545899.001]
  • (PMID = 19352478.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2666118
  • [Keywords] NOTNLM ; Atlantodental interval (ADI) / Atlatoaxial instability (AAI) / Transarticular screw fixation (TAF) / Unilateral / Vertebral artery
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37. Sarma N, Das S, Roy AK: Annular tufted angioma. Indian J Dermatol Venereol Leprol; 2007 Nov-Dec;73(6):435-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Annular tufted angioma.
  • [MeSH-major] Hemangioma / pathology. Skin Neoplasms / pathology


38. Han IH, Kuh SU, Chin DK, Kim KS, Jin BH, Cho YE: Surgical treatment of primary spinal tumors in the conus medullaris. J Korean Neurosurg Soc; 2008 Aug;44(2):72-7
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  • RESULTS: There were ependymoma (13), hemangioblastoma (3), lipoma (3), astrocytoma (3), primitive neuroectodermal tumor (PNET) (2), mature teratoma (1), and capillary hemangioma (1) on histopathologic type.

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  • [Cites] Neurophysiol Clin. 2007 Dec;37(6):407-14 [18083496.001]
  • [Cites] J Neurosurg. 2000 Oct;93(2 Suppl):183-93 [11012047.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2007 Dec 1;69(5):1521-6 [17869023.001]
  • [Cites] Childs Nerv Syst. 2008 Jan;24(1):93-7 [17665203.001]
  • [Cites] Comput Med Imaging Graph. 2008 Jan;32(1):78-81 [17931832.001]
  • [Cites] Eur Spine J. 2007 Nov;16 Suppl 2:S130-9 [17653776.001]
  • [Cites] J Orthop Sci. 2007 May;12(3):227-40 [17530374.001]
  • [Cites] J Clin Neurosci. 2006 Oct;13(8):870-2 [16931024.001]
  • [Cites] J Neurosurg Sci. 2006 Jun;50(2):55-8 [16841029.001]
  • [Cites] Neurosurgery. 2005 May;56(5):972-81; discussion 972-81 [15854245.001]
  • [Cites] J Neurosurg Spine. 2005 Mar;2(3):249-55 [15796348.001]
  • [Cites] J Neurooncol. 2005 Jan;71(2):205-10 [15690140.001]
  • [Cites] Spinal Cord. 2005 Jan;43(1):34-41 [15326473.001]
  • [Cites] Acta Neurochir (Wien). 1998;140(4):309-13 [9689321.001]
  • [Cites] Yonsei Med J. 2004 Jun 30;45(3):533-8 [15227743.001]
  • [Cites] Neurourol Urodyn. 2004;23(1):68-75 [14694461.001]
  • [Cites] Neurosurgery. 2002 May;50(5):1059-63 [11950409.001]
  • [Cites] Childs Nerv Syst. 2008 Feb;24(2):219-23 [17639420.001]
  • (PMID = 19096696.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588334
  • [Keywords] NOTNLM ; Conus medullaris / Primary tumor
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39. Barrey C, Kalamarides M, Polivka M, George B: Cervical Dumbbell Intra-extradural Hemangioblastoma: Total Removal through the Lateral Approach: Technical Case Report. Neurosurgery; 2005 Mar 01;56(3):E625
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  • [Title] Cervical Dumbbell Intra-extradural Hemangioblastoma: Total Removal through the Lateral Approach: Technical Case Report.

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  • (PMID = 28184666.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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40. Till V, Koprivsek K, Stojanovic S, Avramov P, Vulekovic P: Transient cortical blindness following vertebral angiography in a young adult with cerebellar haemangioblastoma. Pediatr Radiol; 2009 Nov;39(11):1223-6
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  • [Title] Transient cortical blindness following vertebral angiography in a young adult with cerebellar haemangioblastoma.
  • We report a long episode of transient cortical blindness in a 17-year-old boy with cerebellar haemangioblastoma, which started during the preoperative vertebral angiography and lasted for 5 days.
  • [MeSH-major] Blindness, Cortical / diagnosis. Blindness, Cortical / etiology. Brain Neoplasms / diagnosis. Cerebral Angiography / adverse effects. Hemangioblastoma / diagnosis. Magnetic Resonance Imaging

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  • [Cites] J Neurosurg. 1974 May;40(5):583-6 [4817802.001]
  • [Cites] Cathet Cardiovasc Diagn. 1994 Feb;31(2):161 [8149434.001]
  • [Cites] Neurology. 1989 Apr;39(4):567-71 [2927682.001]
  • [Cites] Arch Neurol. 2002 May;59(5):851-4 [12020271.001]
  • [Cites] Lancet. 1998 Feb 21;351(9102):570 [9492782.001]
  • [Cites] Clin Exp Neurol. 1992;29:272-6 [1343869.001]
  • [Cites] AJNR Am J Neuroradiol. 2005 Jan;26(1):193; author reply 193-4 [15661726.001]
  • [Cites] Surg Neurol. 2005 Apr;63(4):307-15; discussion 315-6 [15808704.001]
  • (PMID = 19779710.001).
  • [ISSN] 1432-1998
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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41. Dwarakanath S, Suri A, Sharma BS, Mehta VS: Intracranial hemangioblastomas: an institutional experience. Neurol India; 2006 Sep;54(3):276-8
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  • [Title] Intracranial hemangioblastomas: an institutional experience.
  • BACKGROUND AND AIMS: We present our Institutional experience with intracranial hemangioblastomas.
  • MATERIALS AND METHODS: This study included all patients of intracranial hemangioblastomas admitted in our institution over a period of 11 years from January 1992 through June 2003.
  • CONCLUSION: Lifelong surveillance is necessary in cases with hemangioblastomas to identify recurrences especially in those patients having VHL syndrome.
  • [MeSH-major] Brain Neoplasms. Hemangioblastoma. Institutional Practice / statistics & numerical data
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Humans. Male. Retrospective Studies. von Hippel-Lindau Disease / etiology

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  • (PMID = 16936388.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] India
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42. Ammerman JM, Lonser RR, Dambrosia J, Butman JA, Oldfield EH: Long-term natural history of hemangioblastomas in patients with von Hippel-Lindau disease: implications for treatment. J Neurosurg; 2006 Aug;105(2):248-55
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  • [Title] Long-term natural history of hemangioblastomas in patients with von Hippel-Lindau disease: implications for treatment.
  • OBJECT: In the course of their lives most patients with von Hippel-Lindau (VHL) disease require treatment for several symptom-producing hemangioblastomas of the cerebellum, brainstem, or spinal cord.
  • Detection at an early stage of lesions that will later produce symptoms and ultimately require treatment would allow for earlier excision of hemangioblastomas of the spinal cord, brainstem, or cerebellum, and may identify cerebellar hemangioblastomas that can be treated with radiosurgery at a stage before treatment is contraindicated because of tumor size or the presence of an associated cyst.
  • METHODS: To identify features predictive of symptom development that might allow for earlier treatment of smaller, presymptomatic hemangioblastomas in patients with VHL disease, the authors reviewed and analyzed the serial clinical and imaging findings in all patients with VHL disease who were followed up at the National Institutes of Health for more than 10 years.
  • Nineteen patients (10 men and nine women; mean age 32.6 +/- 11.6 years) harboring a total of 143 hemangioblastomas were identified (mean follow-up duration 12.4 +/- 1.4 years).
  • Hemangioblastomas were located in the cerebellum (68 hemangioblastomas, 48% of patients), brainstem (17 hemangioblastomas, 12% of patients), and spinal cord (58 hemangioblastomas, 40% of patients).
  • Despite measurable growth in almost all hemangioblastomas (138 lesions, 97% of patients), only 58 (41% of patients) became symptomatic.
  • Hemangioblastomas grew in a stuttering pattern. (mean growth period 13 +/- 15 months, mean quiescent period 25 +/- 19 months).
  • Twenty-six (45%) of the hemangioblastomas that eventually produced symptoms were not among the tumors that were apparent on the initial MR imaging study.
  • Depending on location, the hemangioblastoma size and/or tumor and cyst growth rates predicted symptom development and the need for treatment (p < 0.05).
  • Cerebellar hemangioblastomas growing faster than 112 mm3/ month or larger than 69 mm3 with associated tumor and cyst growth rates greater than 14 mm3/month became symptomatic (100% sensitivity, 72% specificity).
  • Brainstem hemangioblastomas larger than 245 mm3 with growth rates greater than 0.1 mm3/month became symptomatic (75% sensitivity, 89% specificity).
  • Spinal hemangioblastomas larger than 22 mm3 became symptomatic (79% sensitivity, 94% specificity).
  • CONCLUSIONS: Because hemangioblastomas exhibit a stuttering growth pattern, frequently remain asymptomatic, and do not require treatment for long intervals, unqualified radiographic progression is not an indication for treatment.
  • [MeSH-major] Brain Stem Neoplasms / diagnosis. Cerebellar Neoplasms / diagnosis. Hemangioblastoma / diagnosis. Magnetic Resonance Imaging. Spinal Cord Neoplasms / diagnosis. von Hippel-Lindau Disease / diagnosis
  • [MeSH-minor] Adult. Disease Progression. Early Diagnosis. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neurologic Examination. Patient Care Planning. Prognosis

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  • (PMID = 17219830.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Boström A, Hans FJ, Reinacher PC, Krings T, Bürgel U, Gilsbach JM, Reinges MH: Intramedullary hemangioblastomas: timing of surgery, microsurgical technique and follow-up in 23 patients. Eur Spine J; 2008 Jun;17(6):882-6
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  • [Title] Intramedullary hemangioblastomas: timing of surgery, microsurgical technique and follow-up in 23 patients.
  • Hemangioblastomas are highly vascularised tumors of the central nervous system and account for 1.5-2.5% of all spinal cord tumors.
  • Clinical records of 23 consecutive patients with intramedullary hemangioblastomas who underwent first surgery in our department between 1990 and 2005 were reviewed.
  • In eight patients, a von-Hippel-Lindau disease (VHL) was associated.
  • Following the above-mentioned principles of microsurgical removal of intramedullary hemangioblastomas, operation is possible with a low procedure-related morbidity and can be recommended especially in VHL patients with progressive symptoms or tumor growth during follow-up.
  • Patients without VHL most frequently require hemangioblastoma resection for diagnostic purposes and/or because symptoms prompted an imaging work-up that lead to the discovery of the tumor.
  • [MeSH-major] Hemangioblastoma / surgery. Microsurgery / methods. Spinal Cord Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Treatment Outcome. von Hippel-Lindau Disease / complications

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  • [Cites] AJNR Am J Neuroradiol. 2001 Jan;22(1):206-17 [11158911.001]
  • [Cites] J Neurosurg. 2002 Jul;97(1 Suppl):1-6 [12120629.001]
  • [Cites] Neurosurgery. 2003 Dec;53(6):1306-13; discussion 1313-4 [14633297.001]
  • [Cites] Surg Neurol. 1976 Sep;(3):141-8 [986698.001]
  • [Cites] J Neurosurg. 1989 Jan;70(1):24-30 [2909683.001]
  • [Cites] J Chin Med Assoc. 2005 Jan;68(1):40-4 [15742863.001]
  • [Cites] Neurochirurgia (Stuttg). 1990 Jul;33(4):100-5 [2395499.001]
  • [Cites] No Shinkei Geka. 1991 Feb;19(2):149-55 [2023671.001]
  • [Cites] Neurosurg Rev. 1993;16(3):205-9 [8272209.001]
  • [Cites] Neurosurgery. 1994 Nov;35(5):865-73; discussion 873 [7838335.001]
  • [Cites] J Neurosurg. 1990 Apr;72(4):523-32 [2319309.001]
  • (PMID = 18389290.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2518988
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44. Chen CY, Chen PH, Yao MS, Chu JS, Chan WP: MRI of hemangioblastoma in the conus medullaris. Comput Med Imaging Graph; 2008 Jan;32(1):78-81
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  • [Title] MRI of hemangioblastoma in the conus medullaris.
  • Hemangioblastoma of the conus medullaris with MRI has not been reported before.
  • Histological findings were compatible with the diagnosis of hemangioblastoma.
  • Hemangioblastoma should be included in the differential diagnosis in patients with an enhancing tumor and adjacent engorged vessels of the spinal cord.
  • [MeSH-major] Hemangioblastoma / diagnosis. Spinal Cord / pathology. Spinal Cord Neoplasms / diagnosis

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  • (PMID = 17931832.001).
  • [ISSN] 0895-6111
  • [Journal-full-title] Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
  • [ISO-abbreviation] Comput Med Imaging Graph
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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45. Johnson J, Junewick J, Cottingham S: Phrenic nerve hemangioblastoma in a von Hippel-Lindau patient. AJR Am J Roentgenol; 2005 Mar;184(3 Suppl):S10-1
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  • [Title] Phrenic nerve hemangioblastoma in a von Hippel-Lindau patient.
  • [MeSH-major] Hemangioblastoma / complications. Peripheral Nervous System Neoplasms / complications. Phrenic Nerve. von Hippel-Lindau Disease / complications

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  • (PMID = 15727993.001).
  • [ISSN] 0361-803X
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Ozkurt H, Degirmenci H, Yenice G, Karatag O, Basak M: Huge pancreas helps diagnosis in von Hippel-Lindau disease. Indian J Gastroenterol; 2006 Mar-Apr;25(2):90-1
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  • [Title] Huge pancreas helps diagnosis in von Hippel-Lindau disease.
  • We describe five patients diagnosed with von Hippel-Lindau disease who complained of abdominal distension, pain and discomfort for a long time.
  • Additionally, extrapancreatic findings such as cerebellar hemangioblastoma (3 patients), retinal hemangioblastoma (2), renal cell carcinoma (3), renal adenoma (1), renal cysts (4), and splenic cyst (1) helped to reach the right diagnosis.
  • One patient who had no known associated pathology had a family history of von Hippel-Lindau disease.
  • Pancreatic cysts detected on imaging may be a clue to the diagnosis of von Hippel-Lindau disease.
  • In all patients with multiple pancreatic cysts, this disease should be included in the differential diagnosis.
  • [MeSH-major] Pancreatic Cyst / diagnosis. von Hippel-Lindau Disease / diagnosis

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  • (PMID = 16763339.001).
  • [ISSN] 0254-8860
  • [Journal-full-title] Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
  • [ISO-abbreviation] Indian J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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47. Winestone JS, Lin J, Sanford RA, Boop FA: Subepyndemal hemangioblastomas of the cervicomedullary junction: lessons learned in the management of two cases. Childs Nerv Syst; 2007 Jul;23(7):761-4
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  • [Title] Subepyndemal hemangioblastomas of the cervicomedullary junction: lessons learned in the management of two cases.
  • OBJECTIVE: This retrospective case series analyzes two cases of hemangioblastomas in the cervicomedullary junction.
  • CONCLUSION: Surgery is the treatment of choice for hemangioblastomas of the cervicomedullary junction.
  • Careful monitoring for unique complications, treatment of the tumor as a vascular malformation, and screening for von Hippel Lindau must all be employed to safely care for this challenging group of patients.
  • [MeSH-major] Brain Stem Neoplasms / surgery. Central Nervous System Vascular Malformations / surgery. Hemangioblastoma / surgery. Spinal Cord Neoplasms / surgery
  • [MeSH-minor] Adult. Cervical Vertebrae. Child, Preschool. Female. Humans. Male. Medulla Oblongata. Treatment Outcome. von Hippel-Lindau Disease / complications. von Hippel-Lindau Disease / diagnosis

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  • [Cites] J Neurosurg. 1986 Feb;64(2):317-21 [3944644.001]
  • [Cites] Surg Neurol. 2001 Oct;56(4):218-26; discussion 226-7 [11738662.001]
  • [Cites] Surg Neurol. 1975 Aug;4(2):211-24 [1162593.001]
  • [Cites] J Neurosurg. 2003 Jan;98(1):95-105 [12546357.001]
  • [Cites] Acta Neurochir (Wien). 2001 Sep;143(9):893-6 [11685621.001]
  • (PMID = 17396270.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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48. Katz BJ, Zhang K: Juxtapapillary hemangioblastoma as a manifestation of von Hippel-Lindau disease. Pediatr Int; 2006 Aug;48(4):423-5
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  • [Title] Juxtapapillary hemangioblastoma as a manifestation of von Hippel-Lindau disease.
  • [MeSH-major] Hemangioma, Capillary / etiology. Retinal Neoplasms / etiology. von Hippel-Lindau Disease / complications

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  • (PMID = 16911093.001).
  • [ISSN] 1328-8067
  • [Journal-full-title] Pediatrics international : official journal of the Japan Pediatric Society
  • [ISO-abbreviation] Pediatr Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
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49. Adam Y, Benezech J, Blanquet A, Fuentes JM, Bousigue JY, Debono B, Duplessis E, Espagno C, Plas JY, Lescure JP, Destandau J, Hladky JP, Grunewald P, Mahla K, Remond J, Louis E: [Intramedullary tumors. Results of a national investigation in private neurosurgery]. Neurochirurgie; 2010 Aug;56(4):344-9
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  • [Title] [Intramedullary tumors. Results of a national investigation in private neurosurgery].
  • [Transliterated title] Les tumeurs intramédullaires. Résultat d'une enquête nationale en neurochirurgie libérale.
  • MATERIAL: Seventy-nine cases were distributed in the following manner: ependymomas, 38; astrocytomas, 22; oligodendrogliomas, four; gangliogliomas, two; hemangioblastomas, 10 (nine sporadic cases and one case of Von Hippel-Lindau disease); primitive melanoma, one; and intramedullary neurinomas, two.
  • Tumor removal was complete in the cases of ependymoma and hemangioblastoma and subtotal in the cases of astrocytoma.
  • Hemangioblastoma: 10 cases, nine sporadic and one case of Von Hippel-Lindau disease.

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  • [Copyright] Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20097390.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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50. Yang YM, Wang DM, Jiang HZ, Sha C, Yuan QG, Liu JC: [Treatment of spinal cord hemangioblastoma by microoperations combined with embolization]. Zhonghua Yi Xue Za Zhi; 2008 May 20;88(19):1309-12
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  • [Title] [Treatment of spinal cord hemangioblastoma by microoperations combined with embolization].
  • OBJECTIVE: To investigate the effects of microoperations combined with embolization in treatment of spinal cord hemangioblastoma.
  • METHODS: Thirty-six patients with spinal cord hemangioblastoma, 21 males and 15 females, aged 24.2 (12-48), underwent MRI and digital abstraction angiography.
  • CONCLUSION: Embolization lowers the blood supply of the spinal cord hemangioblastoma, elevates the cure rate, and enlarges the indication of spinal cord hemangioblastoma operation.
  • [MeSH-major] Embolization, Therapeutic / methods. Hemangioblastoma / therapy. Microsurgery / methods. Spinal Cord Neoplasms / therapy

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  • (PMID = 18956698.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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51. Clark WC: Hemangioblastomas of spinal nerve roots and spinal medullary venous congestion. South Med J; 2009 Apr;102(4):347-8
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  • [Title] Hemangioblastomas of spinal nerve roots and spinal medullary venous congestion.
  • [MeSH-major] Hemangioblastoma / complications. Hyperemia / etiology. Medulla Oblongata / blood supply. Medulla Oblongata / pathology. Peripheral Nervous System Neoplasms / complications. Spinal Nerve Roots / pathology

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  • [CommentOn] South Med J. 2009 Apr;102(4):408-10 [19279545.001]
  • (PMID = 19279542.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Comment; Editorial
  • [Publication-country] United States
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52. Akcaglar S, Yavascaoglu I, Vuruskan H, Oktay B: Genetic evaluation of von Hippel-Lindau disease for early diagnosis and improved prognosis. Int Urol Nephrol; 2008;40(3):615-20
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  • [Title] Genetic evaluation of von Hippel-Lindau disease for early diagnosis and improved prognosis.
  • von Hippel-Lindau disease (VHL) is a rare autosomal-dominant disorder in which affected individuals develop tumors in a number of locations.
  • Although none of the kindreds investigated had clinical evidence of VHL disease, 22 were found to have a VHL gene mutation consisting of deletions on the short arm of chromosomes 3, 17, and 19.
  • Detailed clinical examination of the 22 kindreds with a VHL mutation revealed cerebellar hemangioblastoma (three kindreds), meningioma (two) and renal cell carcinoma (five).
  • [MeSH-major] Carcinoma, Renal Cell / genetics. Kidney Neoplasms / genetics. Mutation. von Hippel-Lindau Disease / genetics

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  • [Cites] Acta Neurol Belg. 2002 Jun;102(2):53-62 [12161900.001]
  • [Cites] Adv Cancer Res. 1998;75:163-201 [9709810.001]
  • [Cites] Hum Mol Genet. 1997 Jul;6(7):1051-6 [9215674.001]
  • [Cites] Mol Pathol. 2000 Jun;53(3):137-44 [10897333.001]
  • [Cites] Q J Med. 1990 Nov;77(283):1151-63 [2274658.001]
  • [Cites] Nature. 1988 Mar 17;332(6161):268-9 [2894613.001]
  • [Cites] Medicine (Baltimore). 1997 Nov;76(6):381-91 [9413424.001]
  • [Cites] Nat Genet. 1994 May;7(1):85-90 [7915601.001]
  • [Cites] Genes Chromosomes Cancer. 1997 Jun;19(2):59-76 [9171996.001]
  • [Cites] Cancer. 1990 Mar 1;65(5):1150-4 [2302664.001]
  • [Cites] J Med Genet. 2002 Jan;39(1):1-5 [11826016.001]
  • [Cites] Kidney Int. 1997 Jan;51(1):16-26 [8995713.001]
  • [Cites] Cancer Res. 1995 Sep 15;55(18):4182-7 [7664295.001]
  • (PMID = 18074239.001).
  • [ISSN] 0301-1623
  • [Journal-full-title] International urology and nephrology
  • [ISO-abbreviation] Int Urol Nephrol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


53. McNeill A, Rattenberry E, Barber R, Killick P, MacDonald F, Maher ER: Genotype-phenotype correlations in VHL exon deletions. Am J Med Genet A; 2009 Oct;149A(10):2147-51
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  • Von Hippel-Lindau (VHL) syndrome is a dominantly inherited familial cancer syndrome caused by mutations in the VHL gene.
  • Type 2 subtypes of VHL syndrome are characterized by the presence of pheochromocytoma and the three Type 2 subtypes are associated with differing risks of hemangioblastoma and renal cell carcinoma (RCC).
  • Type 1 VHL syndrome is most commonly caused by germline exon deletions and truncating mutations and is characterized by susceptibility to hemangioblastomas and RCC but not pheochromocytoma.
  • The risks of hemangioblastomas were similar in both groups.
  • These results add to the growing body of evidence suggesting that patients with VHL syndrome caused by large VHL deletions that include C3orf10 may be designated as having a specific subtype (Type 1B) of the disorder.
  • [MeSH-major] Gene Deletion. Phenotype. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / classification
  • [MeSH-minor] Adrenal Gland Neoplasms / complications. Adrenal Gland Neoplasms / genetics. Carcinoma, Renal Cell / complications. Carcinoma, Renal Cell / genetics. Cerebellar Neoplasms / complications. Cerebellar Neoplasms / genetics. Cytoskeletal Proteins / genetics. DNA Mutational Analysis. Exons / genetics. Fanconi Anemia Complementation Group D2 Protein / genetics. Genotype. Germ-Line Mutation. Hemangioblastoma / complications. Hemangioblastoma / genetics. Humans. Kidney Neoplasms / complications. Kidney Neoplasms / genetics. Pheochromocytoma / complications. Pheochromocytoma / genetics. Retinal Neoplasms / complications. Retinal Neoplasms / genetics

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  • (PMID = 19764026.001).
  • [ISSN] 1552-4833
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / BRK1 protein, human; 0 / Cytoskeletal Proteins; 0 / FANCD2 protein, human; 0 / Fanconi Anemia Complementation Group D2 Protein; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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54. Osio A, Fraitag S, Hadj-Rabia S, Bodemer C, de Prost Y, Hamel-Teillac D: Clinical spectrum of tufted angiomas in childhood: a report of 13 cases and a review of the literature. Arch Dermatol; 2010 Jul;146(7):758-63
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  • [Title] Clinical spectrum of tufted angiomas in childhood: a report of 13 cases and a review of the literature.
  • BACKGROUND: Tufted angioma (TA) is a rare benign vascular tumor that mostly appears during infancy or early childhood.
  • Histologic tufts of capillaries infiltrating the whole dermis in a "cannonball" distribution pattern associated with dilated lymphatic vessels are characteristic of the disease and confirm the diagnosis.
  • Few case series of TA have been published, and the morphologic structure and evolution of TA seem to vary.
  • [MeSH-major] Hemangioma / pathology. Skin / pathology. Skin Neoplasms / pathology

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  • (PMID = 20644037.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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55. Meyerle CB, Dahr SS, Wetjen NM, Jirawuthiworavong GV, Butman JA, Lonser RR, Oldfield E, Rodriguez-Coleman H, Wong WT, Chew EY: Clinical course of retrobulbar hemangioblastomas in von Hippel-Lindau disease. Ophthalmology; 2008 Aug;115(8):1382-9
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  • [Title] Clinical course of retrobulbar hemangioblastomas in von Hippel-Lindau disease.
  • OBJECTIVE: To report clinical findings of rare retrobulbar optic nerve hemangioblastomas associated with von Hippel-Lindau disease (VHL).
  • METHODS: The clinical course and magnetic resonance imaging findings of patients with VHL and hemangioblastomas affecting the anterior visual pathway from the intraorbital optic nerve to the optic chiasm are reviewed.
  • MAIN OUTCOME MEASURE: Clinical course of retrobulbar optic nerve hemangioblastomas.
  • All had other CNS lesions and retinal hemangioblastomas.
  • Four patients underwent surgical resection of an intracranial hemangioblastoma.
  • Growth patterns and pathology are similar to those of other hemangioblastomas in the CNS.
  • CONCLUSIONS: Although these lesions are rare, patients with VHL who present with signs of optic neuropathy should be evaluated for anterior visual pathway hemangioblastomas impinging on the optic nerve from the orbit to the chiasm.
  • On neuroimaging, the hemangioblastomas may demonstrate chiasmal or optic tract edema, associated cysts, and T(2) flow voids.
  • [MeSH-major] Hemangioblastoma / physiopathology. Optic Chiasm / pathology. Optic Nerve Neoplasms / physiopathology. von Hippel-Lindau Disease / physiopathology

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  • (PMID = 18395800.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z99 EY999999; United States / Intramural NIH HHS / / ZIE EY000487-01
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. Chakraborty S, Gharami RC, Das NK, Datta PK: Annular tufted angioma: a rare entity. Int J Dermatol; 2009 Jun;48(6):614-6
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  • [Title] Annular tufted angioma: a rare entity.
  • [MeSH-major] Dermis / blood supply. Dermis / pathology. Hemangioma / pathology. Vascular Neoplasms / pathology

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  • (PMID = 19538371.001).
  • [ISSN] 1365-4632
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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57. Lemeta S, Salmenkivi K, Pylkkänen L, Sainio M, Saarikoski ST, Arola J, Heikkilä P, Haglund C, Husgafvel-Pursiainen K, Böhling T: Frequent loss of heterozygosity at 6q in pheochromocytoma. Hum Pathol; 2006 Jun;37(6):749-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Most PCCs are sporadic, but they also occur in inherited tumor syndromes, including von Hippel-Lindau disease.
  • Moreover, we sought to compare PCC with capillary hemangioblastoma, another von Hippel-Lindau disease-associated tumor that we previously found to harbor frequent loss of heterozygosity (LOH) at 6q.
  • Similar to our findings for capillary hemangioblastomas, our data for the first time suggest that one or several tumor suppressor genes located at 6q, particularly at 6q23-24, may play a role in the tumorigenesis of PCCs.
  • [MeSH-minor] Adult. Aged. Alleles. DNA, Neoplasm / analysis. Female. Gene Deletion. Genetic Markers. Hemangioblastoma / genetics. Hemangioblastoma / pathology. Humans. Male. Microsatellite Repeats. Middle Aged. Tumor Burden

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  • (PMID = 16733217.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / DNA, Neoplasm; 0 / Genetic Markers; 0 / PLAGL1 protein, human; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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58. Alberola FT, Betlloch I, Montero LC, Nortes IB, Martínez NL, Paz AM: Congenital tufted angioma: Case report and review of the literature. Dermatol Online J; 2010;16(5):2
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  • [Title] Congenital tufted angioma: Case report and review of the literature.
  • Tufted angiomas (TA) are rare benign vascular tumors of unknown pathogenesis.
  • Tufted angiomas have a characteristic histology consisting of a proliferation of endothelial cells forming lobules with the typical "shotgun" distribution.
  • [MeSH-major] Hemangioma / congenital. Skin Neoplasms / congenital


59. Lonser RR, Oldfield EH: Microsurgical resection of spinal cord hemangioblastomas. Neurosurgery; 2005 Oct;57(4 Suppl):372-6; discussion 372-6
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  • [Title] Microsurgical resection of spinal cord hemangioblastomas.
  • Hemangioblastomas are not uncommon intramedullary spinal cord neoplasms.
  • They are highly vascular, benign tumors that occur either sporadically or in the presence of von Hippel-Lindau disease.
  • [MeSH-major] Hemangioblastoma / surgery. Microsurgery / methods. Spinal Cord Neoplasms / surgery

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  • (PMID = 16234688.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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60. Mao XC, Su ZP, Yu WQ, Zheng WM, Zeng YJ: Familial and genetic researches on three Chinese families with von Hippel-Lindau disease. Neurol Res; 2009 Sep;31(7):743-7
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  • [Title] Familial and genetic researches on three Chinese families with von Hippel-Lindau disease.
  • OBJECTIVE: Hemangioblastoma of the central nervous system (CNS) occur as sporadic tumors or as a part of von Hippel-Lindau (VHL) disease, an autosomal dominant hereditary tumor syndrome caused by germline mutation of the VHL tumor suppressor gene.
  • This study shows the clinical characteristics of three large Chinese families with VHL disease and evaluates the consequence of the genetic test for the diagnosis of VHL disease and clinical screening of the family members.
  • METHODS: DNA is extracted from peripheral blood in 43 members from three large families with VHL disease and amplified by PCR to three exons of the VHL gene.
  • Twenty VHL disease patients in the three families have the most common manifestation of CNS hemangioblastoma.
  • CONCLUSION: The DNA analysis of VHL germline mutations is clearly superior to clinical information to diagnose VHL disease.
  • The CNS hemangioblastoma is the early manifestation in VHL disease.
  • It is recommended that every patient with CNS hemangioblastoma should be screened for VHL gene mutation.
  • [MeSH-major] Genetic Predisposition to Disease. Mutation / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics
  • [MeSH-minor] Adolescent. Adult. Asian Continental Ancestry Group / ethnology. Brain Neoplasms / etiology. Brain Neoplasms / genetics. DNA Mutational Analysis. Female. Genetic Testing. Genotype. Hemangioblastoma / etiology. Hemangioblastoma / genetics. Humans. Male. Middle Aged. Phenotype. Retrospective Studies. Severity of Illness Index. Young Adult

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  • (PMID = 19133167.001).
  • [ISSN] 0161-6412
  • [Journal-full-title] Neurological research
  • [ISO-abbreviation] Neurol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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61. Enjolras O, Picard A, Soupre V: [Congenital haemangiomas and other rare infantile vascular tumours]. Ann Chir Plast Esthet; 2006 Aug-Oct;51(4-5):339-46
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  • Tufted angioma and kaposiform haemangioendothelioma are histopathologically well characterized; in addition they are now considered as part of a same spectrum of vascular tumours, with the contribution of lymphatic endothelial cells in their proliferation.
  • [MeSH-major] Hemangioma / congenital. Neoplasms, Vascular Tissue / diagnosis. Skin Neoplasms / congenital
  • [MeSH-minor] Biomarkers, Tumor / analysis. Blood Platelets / pathology. Child. Disseminated Intravascular Coagulation / diagnosis. Glucose Transporter Type 1 / analysis. Hemangioendothelioma / diagnosis. Hemangioma, Capillary / congenital. Humans. Infant. Prognosis. Remission, Spontaneous. Syndrome. Thrombocytopenia / diagnosis

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  • (PMID = 16997442.001).
  • [ISSN] 0294-1260
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glucose Transporter Type 1; 0 / SLC2A1 protein, human
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62. Moch H: [Von-Hippel-Lindau (VHL) protein function by initiation and progression of renal cancer]. Pathologe; 2008 Nov;29 Suppl 2:149-52
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  • [Title] [Von-Hippel-Lindau (VHL) protein function by initiation and progression of renal cancer].
  • Germ line inactivation of the von-Hippel-Lindau (VHL) tumor suppressor gene causes von Hippel-Lindau hereditary cancer syndrome, and somatic mutations of this gene have been linked to the development of sporadic hemangioblastomas and clear cell renal carcinomas.
  • [MeSH-major] Alleles. Carcinoma, Renal Cell / genetics. Kidney Neoplasms / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics

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  • [Cites] Mol Cell Biol. 2008 Jul;28(14 ):4536-48 [18474617.001]
  • [Cites] Nature. 1999 May 20;399(6733):271-5 [10353251.001]
  • [Cites] Lancet. 2003 Jun 14;361(9374):2059-67 [12814730.001]
  • [Cites] Cell Cycle. 2007 May 2;6(9):1006-10 [17457049.001]
  • [Cites] Curr Opin Genet Dev. 2005 Jun;15(3):308-14 [15917207.001]
  • [Cites] Dev Cell. 2005 Nov;9(5):617-28 [16256737.001]
  • [Cites] Cell Cycle. 2007 Aug 1;6(15):1809-13 [17671433.001]
  • [Cites] Mol Cell. 2006 May 5;22(3):395-405 [16678111.001]
  • [Cites] Nat Cell Biol. 2007 May;9(5):588-95 [17450132.001]
  • [Cites] Nature. 1988 Mar 17;332(6161):268-9 [2894613.001]
  • [Cites] Nat Genet. 1994 May;7(1):85-90 [7915601.001]
  • [Cites] Curr Opin Genet Dev. 2007 Feb;17(1):71-7 [17208433.001]
  • [Cites] Science. 1993 May 28;260(5112):1317-20 [8493574.001]
  • [Cites] Proc Natl Acad Sci U S A. 1988 Mar;85(5):1571-5 [2894030.001]
  • [Cites] Genes Dev. 2006 Mar 1;20(5):557-70 [16510872.001]
  • [Cites] Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9700-4 [7937876.001]
  • [Cites] Oncogene. 2008 Feb 7;27(7):1004-12 [17700531.001]
  • [Cites] Cancer Cell. 2007 Aug;12(2):108-13 [17692803.001]
  • [Cites] Cancer Cell. 2007 Apr;11(4):335-47 [17418410.001]
  • [Cites] Mol Cell. 1998 Jun;1(7):959-68 [9651579.001]
  • [Cites] Am J Pathol. 2003 Sep;163(3):1013-20 [12937142.001]
  • [Cites] EMBO J. 2004 May 5;23 (9):1949-56 [15071503.001]
  • [Cites] Nature. 2003 Sep 18;425(6955):307-11 [13679920.001]
  • [Cites] Mol Cell. 2007 Oct 12;28(1):15-27 [17936701.001]
  • [Cites] J Pathol. 2008 Mar;214(4):464-71 [18189328.001]
  • [Cites] Curr Opin Cell Biol. 2007 Dec;19(6):685-90 [18006292.001]
  • [Cites] Cancer Res. 1998 Jun 1;58(11):2304-9 [9622063.001]
  • [Cites] Cell. 2008 Feb 8;132(3):344-62 [18267068.001]
  • [Cites] Cancer Cell. 2007 May;11(5):407-20 [17482131.001]
  • [Cites] EMBO J. 2008 Jun 18;27(12 ):1747-57 [18497742.001]
  • [Cites] J Clin Oncol. 2004 Dec 15;22(24):4991-5004 [15611513.001]
  • (PMID = 18751708.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 2.3.2.27 / Von Hippel-Lindau Tumor Suppressor Protein; EC 6.3.2.- / VHL protein, human
  • [Number-of-references] 32
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63. Imanaka M, Iida K, Takahashi K, Tsuji K, Nishizawa H, Fukuoka H, Takeno R, Takahashi Y, Okimura Y, Kaji H, Chihara K: The N131S mutation in the von Hippel-Lindau gene in a Japanese family with pheochromocytoma and hemangioblastomas. Endocr J; 2006 Dec;53(6):819-27
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  • [Title] The N131S mutation in the von Hippel-Lindau gene in a Japanese family with pheochromocytoma and hemangioblastomas.
  • von Hippel-Lindau (VHL) disease (VHLD) is a hereditary autosomal dominant syndrome that causes various benign and malignant tumors.
  • Here, we report a mutation in the VHL gene in a Japanese family with VHLD type 2A, characterized by pheochromocytoma (PHE), and hemangioblastomas (HAB) in both the retina and thoracic spinal cord but without renal cell carcinoma (RCC).
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Cerebellar Neoplasms / genetics. Hemangioblastoma / genetics. Mutation. Pheochromocytoma / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 17001110.001).
  • [ISSN] 0918-8959
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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64. Crisi G, Giombelli E, Ventura E: Non-von Hippel-Lindau Hemangioblastoma in the Hippocampus: Characterization with Time-Resolved MRA Using TRICKS Sequence at 3T. A Case Report. Neuroradiol J; 2010 Sep;23(4):416-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-von Hippel-Lindau Hemangioblastoma in the Hippocampus: Characterization with Time-Resolved MRA Using TRICKS Sequence at 3T. A Case Report.
  • Supratentorial hemangioblastomas (HBs) are exceedingly rare tumors accounting for 5%-10% of all HBs and usually present in the setting of von Hippel-Lindau (VHL) disease.
  • Isolated HBs of the central nervous system also occur as a result of spontaneous mutation in the absence of any clinical manifestations of VHL disease.
  • We describe the TRICKS findings in a case of isolated hemangioblastoma in the hippocampus without VHL disease.
  • To our knowledge, this is the second case report of a hippocampal non-VHL hemangioblastoma.

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  • (PMID = 24148630.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Pamir MN, Peker S, Ozek MM, Dinçer A: Intraoperative MR imaging: preliminary results with 3 tesla MR system. Acta Neurochir Suppl; 2006;98:97-100
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  • Lesions were pituitary adenoma in 10, low grade glial tumor in 9, meningioma and high grade glial tumor in 2 each and metastasis, haemangioblastoma and chordoma in one each.

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  • (PMID = 17009706.001).
  • [ISSN] 0065-1419
  • [Journal-full-title] Acta neurochirurgica. Supplement
  • [ISO-abbreviation] Acta Neurochir. Suppl.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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66. Pandia MP, Bithal PK, Sharma MS, Bhagat H, Prasanna B: Use of spontaneous ventilation to monitor the effects of posterior fossa surgery in the sitting position. J Clin Neurosci; 2009 Jul;16(7):968-9
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  • We describe the successful excision, guided by spontaneous ventilation, of a cervico-medullary hemangioblastoma in a 22-year-old female in the sitting position.
  • [MeSH-major] Hemangioblastoma / surgery. Infratentorial Neoplasms / surgery. Monitoring, Intraoperative. Neurosurgical Procedures / methods


67. Rohana AG, Norazmi MK, Norlaila M: A rare case of Von Hippel Lindau disease. Med J Malaysia; 2006 Jun;61(2):254-7
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  • [Title] A rare case of Von Hippel Lindau disease.
  • It may occur sporadically or be associated as part of a tumour syndrome including Von Hippel Lindau (VHL), Multiple Endocrine Neoplasia (MEN) 2 and Neurofibromatosis Type 1.
  • VHL is associated with multi-organ involvement of benign and malignant tumours characterized by the presence of retinal angiomas, hemangioblastomas of the cerebellum and spinal cord, renal cell carcinomas, pheochromocytomas and other cystic lesions in the kidneys, pancreas, and epididymis.
  • It is a rare disorder with prevalence estimated at 2-3 per 100,000.
  • This case report describes a 37 years old Chinese gentleman who presented to our institution for further management of bilateral pheochromocytoma and retinal angioblastoma with problems of duodenal ulcer and anaemia.
  • With these features the criteria for the diagnosis of von Hippel Lindau disease was established.
  • [MeSH-major] von Hippel-Lindau Disease / diagnosis

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  • (PMID = 16898326.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Malaysia
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68. Matsuyama Y, Sakai Y, Katayama Y, Imagama S, Ito Z, Wakao N, Sato K, Kamiya M, Yukawa Y, Kanemura T, Yanase M, Ishiguro N: Surgical results of intramedullary spinal cord tumor with spinal cord monitoring to guide extent of resection. J Neurosurg Spine; 2009 May;10(5):404-13
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  • The tumor types included astrocytoma (12 cases), ependymoma (46 cases), hemangioblastoma (16 cases), cavernous hemangioma (17 cases), and others (15 cases overall: gangliocytoma, 1; germ cell tumor, 1; lymphoma, 3; neurinoma, 1; meningioma, 1; oligodendroglioma, 1; sarcoidosis, 2; glioma, 1; and unknown, 4).
  • [MeSH-minor] Adolescent. Adult. Aged. Astrocytoma / surgery. Child. Ependymoma / surgery. Female. Follow-Up Studies. Hemangioblastoma / surgery. Hemangioma, Cavernous / surgery. Humans. Male. Middle Aged. Postoperative Complications. Prognosis. Prospective Studies. Walking

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  • (PMID = 19442001.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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69. Knauth K, Cartwright E, Freund S, Bycroft M, Buchberger A: VHL mutations linked to type 2C von Hippel-Lindau disease cause extensive structural perturbations in pVHL. J Biol Chem; 2009 Apr 17;284(16):10514-22
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  • [Title] VHL mutations linked to type 2C von Hippel-Lindau disease cause extensive structural perturbations in pVHL.
  • pVHL (von Hippel-Lindau tumor suppressor protein) is the substrate recognition subunit of the CBC(VHL) ubiquitin ligase complex promoting the degradation of hypoxia-inducible factor subunits, HIF-1/2alpha.
  • Mutational inactivation of pVHL causes the hereditary von Hippel-Lindau tumor syndrome, which predisposes affected individuals to hemangioblastomas, renal cell carcinomas, and pheochromocytomas.
  • Whereas the development of hemangioblastomas and renal cell carcinomas has been attributed to impaired HIF-1/2alpha down-regulation by pVHL mutant proteins, the molecular defects underlying the development of pheochromocytomas are still unknown.
  • Here, we present a detailed biochemical analysis of pVHL mutant proteins linked to type 2C (pheochromocytoma only) von Hippel-Lindau disease.
  • [MeSH-major] Mutation. Protein Conformation. Von Hippel-Lindau Tumor Suppressor Protein / chemistry. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics

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  • [Cites] Science. 2001 Nov 9;294(5545):1337-40 [11598268.001]
  • [Cites] Science. 1999 Apr 16;284(5413):455-61 [10205047.001]
  • [Cites] Science. 2002 Jun 7;296(5574):1886-9 [12004076.001]
  • [Cites] Cancer Cell. 2002 Apr;1(3):237-46 [12086860.001]
  • [Cites] Nature. 2002 Jun 27;417(6892):975-8 [12050673.001]
  • [Cites] J Biol Chem. 2002 Aug 16;277(33):30388-93 [12048197.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Nov;87(11):5241-6 [12414898.001]
  • [Cites] Nat Cell Biol. 2003 Jan;5(1):64-70 [12510195.001]
  • [Cites] Lancet. 2003 Jun 14;361(9374):2059-67 [12814730.001]
  • [Cites] Mol Cell. 2003 Nov;12(5):1213-24 [14636579.001]
  • [Cites] Toxicol Lett. 2004 Jun 15;151(1):301-10 [15177666.001]
  • [Cites] Nucleic Acids Res. 1990 Jun 25;18(12):3587-96 [2194165.001]
  • [Cites] JAMA. 1995 Oct 11;274(14):1149-51 [7563486.001]
  • [Cites] J Med Genet. 1995 Nov;32(11):885-6 [8592333.001]
  • [Cites] J Clin Endocrinol Metab. 1996 Mar;81(3):1035-7 [8772572.001]
  • [Cites] J Natl Cancer Inst. 1999 May 19;91(10):854-61 [10340905.001]
  • [Cites] Nature. 1999 May 20;399(6733):271-5 [10353251.001]
  • [Cites] Genes Dev. 2004 Dec 15;18(24):3055-65 [15601820.001]
  • [Cites] Nat Rev Mol Cell Biol. 2005 Jan;6(1):9-20 [15688063.001]
  • [Cites] J Cell Biol. 2005 Mar 14;168(6):911-20 [15767462.001]
  • [Cites] Cancer Cell. 2005 Aug;8(2):91-3 [16098460.001]
  • [Cites] Cancer Cell. 2005 Aug;8(2):155-67 [16098468.001]
  • [Cites] Oncogene. 2006 Jan 19;25(3):370-7 [16261165.001]
  • [Cites] Cancer Res. 2006 Feb 1;66(3):1313-9 [16452184.001]
  • [Cites] Am J Med Genet A. 2006 Apr 1;140(7):685-90 [16502427.001]
  • [Cites] Cancer Res. 2006 Apr 1;66(7):3567-75 [16585181.001]
  • [Cites] J Am Soc Nephrol. 2006 Jul;17(7):1801-6 [16775032.001]
  • [Cites] J Biol Chem. 2007 May 4;282(18):13264-9 [17339318.001]
  • [Cites] Nat Cell Biol. 2007 May;9(5):588-95 [17450132.001]
  • [Cites] Mol Cell Biol. 2007 Aug;27(15):5381-92 [17526729.001]
  • [Cites] Cell Cycle. 2007 Aug 1;6(15):1809-13 [17671433.001]
  • [Cites] Annu Rev Pathol. 2007;2:145-73 [18039096.001]
  • [Cites] Curr Opin Oncol. 2008 Jan;20(1):83-9 [18043261.001]
  • [Cites] Curr Opin Cell Biol. 2007 Dec;19(6):685-90 [18006292.001]
  • [Cites] Nucleic Acids Res. 2007;35(21):e142 [17986458.001]
  • [Cites] Oncogene. 2008 Feb 7;27(7):1004-12 [17700531.001]
  • [Cites] Mol Cell Biol. 2008 May;28(10):3386-400 [18332118.001]
  • [Cites] Mol Cell. 2008 May 23;30(4):393-402 [18498744.001]
  • [Cites] Mol Cell. 1999 Dec;4(6):1051-61 [10635329.001]
  • [Cites] Nat Cell Biol. 2000 Jul;2(7):423-7 [10878807.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8507-12 [10900011.001]
  • [Cites] J Biol Chem. 2000 Aug 18;275(33):25733-41 [10823831.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10430-5 [10973499.001]
  • [Cites] J Med Genet. 2000 Dec;37(12):939-43 [11106358.001]
  • [Cites] Protein Expr Purif. 2001 Feb;21(1):224-34 [11162410.001]
  • [Cites] Science. 2001 Apr 20;292(5516):464-8 [11292862.001]
  • [Cites] Science. 2001 Apr 20;292(5516):468-72 [11292861.001]
  • [Cites] Hum Mol Genet. 2001 May 1;10(10):1019-27 [11331612.001]
  • [Cites] Hum Mol Genet. 2001 May 1;10(10):1029-38 [11331613.001]
  • [Cites] EMBO J. 2001 Sep 17;20(18):5197-206 [11566883.001]
  • [Cites] Mol Cell Biol. 2002 Mar;22(6):1947-60 [11865071.001]
  • [Cites] Genes Dev. 1998 Jun 15;12(12):1769-74 [9637678.001]
  • [Cites] Mol Cell. 1998 Jun;1(7):959-68 [9651579.001]
  • [Cites] Cell. 2001 Oct 5;107(1):43-54 [11595184.001]
  • (PMID = 19228690.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / MC/ U105459896
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Multiprotein Complexes; 0 / Recombinant Proteins; EC 2.3.2.27 / Von Hippel-Lindau Tumor Suppressor Protein
  • [Other-IDs] NLM/ PMC2667738
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70. Tago M, Terahara A, Shin M, Maruyama K, Kurita H, Nakagawa K, Ohtomo K: Gamma knife surgery for hemangioblastomas. J Neurosurg; 2005 Jan;102(s_supplement):171-174
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  • [Title] Gamma knife surgery for hemangioblastomas.
  • OBJECT: The authors reviewed their 14-year experience using stereotactic radiosurgery for the treatment of hemangioblastomas and define the role and the proper strategy for radiosurgery of this condition.
  • METHODS: This is a retrospective study of 38 hemangioblastomas in 13 patients.
  • Seven patients had von Hippel-Lindau disease.
  • CONCLUSIONS: Gamma knife surgery is a safe and effective method to control hemangioblastomas for as many as 10 years.

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  • (PMID = 28306464.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / hemangioblastoma / stereotactic radiosurgery / von Hippel-Lindau disease
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71. van Rooijen E, Voest EE, Logister I, Bussmann J, Korving J, van Eeden FJ, Giles RH, Schulte-Merker S: von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish. Dis Model Mech; 2010 May-Jun;3(5-6):343-53
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  • [Title] von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish.
  • Biallelic inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene predisposes human patients to the development of highly vascularized neoplasms in multiple organ systems.
  • Significantly, vessels in the brain and eye express cxcr4a, a marker gene expressed by tumor and vascular cells in VHL-associated hemangioblastomas and renal cell carcinomas.
  • [MeSH-minor] Animals. Disease Models, Animal. Edema / complications. Edema / pathology. Humans. Macula Lutea / metabolism. Macula Lutea / pathology. Mutant Proteins / metabolism. Receptors, Vascular Endothelial Growth Factor / antagonists & inhibitors. Receptors, Vascular Endothelial Growth Factor / metabolism. Retinal Detachment / complications. Retinal Detachment / pathology. Signal Transduction

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  • (PMID = 20335444.001).
  • [ISSN] 1754-8411
  • [Journal-full-title] Disease models & mechanisms
  • [ISO-abbreviation] Dis Model Mech
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / / C23207/A8066
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Mutant Proteins; 0 / Tumor Suppressor Proteins; 0 / Vhl protein, zebrafish; 0 / Zebrafish Proteins; EC 2.7.10.1 / Receptors, Vascular Endothelial Growth Factor
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72. Miyata S, Mikami T, Minamida Y, Akiyama Y, Houkin K: Suprasellar hemangioblastoma. J Neuroophthalmol; 2008 Dec;28(4):325-6
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  • [Title] Suprasellar hemangioblastoma.
  • The hypothalamus appeared to be the origin of the mass, which proved to be hemangioblastoma, a rare tumor in this location.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Hemangioblastoma / pathology. Hypothalamic Neoplasms / pathology. Hypothalamus / pathology. Third Ventricle / pathology

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  • (PMID = 19145134.001).
  • [ISSN] 1536-5166
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Antigens, CD34; 0 / Biomarkers, Tumor
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73. Oppenlander ME, Spetzler RF: Advances in spinal hemangioblastoma surgery. World Neurosurg; 2010 Jul;74(1):116-7
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  • [Title] Advances in spinal hemangioblastoma surgery.
  • [MeSH-major] Hemangioblastoma / surgery. Microsurgery / methods. Spinal Cord Neoplasms / surgery. von Hippel-Lindau Disease / surgery

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  • [CommentOn] World Neurosurg. 2010 Jul;74(1):200-5 [21300014.001]
  • (PMID = 21299999.001).
  • [ISSN] 1878-8769
  • [Journal-full-title] World neurosurgery
  • [ISO-abbreviation] World Neurosurg
  • [Language] eng
  • [Publication-type] Comment; Journal Article
  • [Publication-country] United States
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74. Pavesi G, Feletti A, Berlucchi S, Opocher G, Martella M, Murgia A, Scienza R: Neurosurgical treatment of von Hippel-Lindau-associated hemangioblastomas: benefits, risks and outcome. J Neurosurg Sci; 2008 Jun;52(2):29-36
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  • [Title] Neurosurgical treatment of von Hippel-Lindau-associated hemangioblastomas: benefits, risks and outcome.
  • AIM: Von Hippel-Lindau (VHL) disease is a genetic syndrome predisposing to central nervous system (CNS) hemangioblastomas and several lesions in many organs.
  • METHODS: The authors evaluated 20 VHL subjects (7 males and 13 females, age at surgery 32+/-10 years) who underwent 28 operations in order to remove 48 CNS hemangioblastomas and 1 endolymphatic sac tumor.
  • Genetic testing revealing the presence of a VHL disease-causing mutation was a prerequisite for inclusion in the study.
  • Symptomatic hemangioblastomas were associated with a cyst or a syrinx in 22/27 circumstances (81%).
  • CONCLUSION: VHL-associated hemangioblastomas generally affect a young adult population and can be successfully removed, either when symptomatic, or when they reach a critical volume.
  • Microsurgery of hemangioblastomas has a favourable impact on survival and quality of life of VHL patients, although it is strongly influenced by preoperative conditions.
  • Transient surgical complications are possible, particularly with brainstem and spinal cord hemangioblastomas.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Cerebellar Neoplasms / surgery. Hemangioblastoma / etiology. Hemangioblastoma / surgery. von Hippel-Lindau Disease / complications

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  • (PMID = 18500215.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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75. Ingold B, Wild PJ, Nocito A, Amin MB, Storz M, Heppner FL, Moch H: Renal cell carcinoma marker reliably discriminates central nervous system haemangioblastoma from brain metastases of renal cell carcinoma. Histopathology; 2008 May;52(6):674-81
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  • [Title] Renal cell carcinoma marker reliably discriminates central nervous system haemangioblastoma from brain metastases of renal cell carcinoma.
  • AIMS: The distinction between central nervous system (CNS) metastases of clear cell renal cell carcinoma (RCC) and CNS haemangioblastoma still poses a challenge to the pathologist.
  • Since both entities occur in von Hippel-Lindau disease, this aggravates the issue.
  • The aim was to assess two distinct clones of the RCC-ma for their potential to: (i) identify primary RCCs and (ii) differentiate between CNS metastases of clear cell RCC and CNS haemangioblastomas.
  • Importantly, 50.9% of CNS metastases of clear cell RCCs (n = 55) exhibited RCC-ma expression, whereas all CNS haemangioblastomas (71) were negative.
  • [MeSH-major] Antibodies, Monoclonal. Brain Neoplasms / diagnosis. Brain Neoplasms / secondary. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Hemangioblastoma / diagnosis. Kidney Neoplasms / pathology

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  • (PMID = 18393979.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Biomarkers, Tumor; EC 3.4.24.11 / Neprilysin
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76. Zhang J, Chen HG, Xue W, Zhou LX, Huang YR: [Large germline deletion of the VHL gene in Chinese families with von Hippel-Lindau syndrome]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2009 Oct;26(5):539-41
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  • [Title] [Large germline deletion of the VHL gene in Chinese families with von Hippel-Lindau syndrome].
  • OBJECTIVE: To investigate the large germline deletion of the VHL gene in Chinese families with von Hippel-Lindau disease (VHL).
  • Of the 2 families with the complete deletions, patients developed multi-centric hemangioblastoma in the retina and central nervous system (CNS), and none developed renal cell carcinoma (RCC).
  • CONCLUSION: Partial and complete VHL gene deletions could be detected in Chinese kindreds with von Hippel-Lindau disease and the test for large deletion of the VHL gene should be implemented in routine DNA diagnosis for VHL disease.
  • Further investigations are required to confirm that entire VHL deletions may be associated with a high risk of hemangioblastomas in the retina and central nervous system.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Gene Deletion. Germ-Line Mutation. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics

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  • (PMID = 19806577.001).
  • [ISSN] 1003-9406
  • [Journal-full-title] Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
  • [ISO-abbreviation] Zhonghua Yi Xue Yi Chuan Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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77. Plon SE, Nathanson K: Inherited susceptibility for pediatric cancer. Cancer J; 2005 Jul-Aug;11(4):255-67
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  • In this article, we review the childhood malignancies that are associated with at least a 10% likelihood of being caused by a genetic susceptibility to cancer and therefore warrant consideration for a genetic evaluation; these malignancies include retinoblastoma, adrenocortical carcinoma, atypical teratoid and malignant rhabdoid tumors, optic pathway tumors, juvenile myelomonocytic leukemia, malignant peripheral nerve sheath tumors, vestibular schwannomas, endolymphatic sac tumors, hemangioblastomas, medullary thyroid cancer, pheochromocytomas, and paragangliomas.
  • [MeSH-major] Genetic Predisposition to Disease. Neoplasms / genetics

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  • (PMID = 16197716.001).
  • [ISSN] 1528-9117
  • [Journal-full-title] Cancer journal (Sudbury, Mass.)
  • [ISO-abbreviation] Cancer J
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / K08-CA084030; United States / NCI NIH HHS / CA / U24-CA78142-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review
  • [Publication-country] United States
  • [Number-of-references] 76
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78. Hussein MR: Central nervous system capillary haemangioblastoma: the pathologist's viewpoint. Int J Exp Pathol; 2007 Oct;88(5):311-24
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  • [Title] Central nervous system capillary haemangioblastoma: the pathologist's viewpoint.
  • Haemangioblastomas are rare neoplasms of uncertain histogenesis.
  • Most haemangioblastomas are sporadic but up to one quarter are associated with Von Hippel-Lindau disease (VHL).
  • Although a fairly good number of haemangioblastomas were reported, a lack of side-by-side analysis of these reports has resulted in tentative conclusions that merely offer a first glimpse at their clinicopathologic diversity and histogenesis.
  • Haemangioblastomas occur either as a part of VHL disease (25-30%, inherited mutation of VHL gene on 3p25-26 chromosome) or as sporadic tumours (often with somatic mutation of VHL gene).
  • Immunostaining is important for separation of haemangioblastomas from other tumours with similar histology.
  • The rich vascularity of haemangioblastomas is due to overexpression of vascular endothelial growth factors.
  • Moreover, 'stromal' cells represent the neoplastic cells of haemangioblastomas and are capable of forming blood islands with extramedullary haematopoiesis.
  • [MeSH-major] Hemangioblastoma / pathology
  • [MeSH-minor] Brain Stem Neoplasms / genetics. Brain Stem Neoplasms / pathology. Central Nervous System Neoplasms / genetics. Central Nervous System Neoplasms / pathology. Cerebellar Neoplasms / genetics. Cerebellar Neoplasms / pathology. Germ-Line Mutation. Humans. Immunohistochemistry. Mutation. Spinal Cord Neoplasms / genetics. Spinal Cord Neoplasms / pathology. Vascular Endothelial Growth Factor A / analysis. Vascular Endothelial Growth Factor A / metabolism. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics. von Hippel-Lindau Disease / pathology

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  • [Cites] J Neuropathol Exp Neurol. 1996 May;55(5):522-7 [8627342.001]
  • [Cites] Pol Arch Med Wewn. 1996 Feb;95(2):145-6 [8677209.001]
  • [Cites] Pathologica. 1995 Oct;87(5):518-21 [8868178.001]
  • [Cites] Acta Neuropathol. 1996 Nov;92(5):461-6 [8922057.001]
  • [Cites] Hum Pathol. 1997 May;28(5):540-3 [9158701.001]
  • [Cites] Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8761-6 [9238051.001]
  • [Cites] Ann N Y Acad Sci. 1997 Sep 17;824:112-23 [9382436.001]
  • [Cites] J Neuropathol Exp Neurol. 1997 Dec;56(12):1349-55 [9413283.001]
  • [Cites] Arq Neuropsiquiatr. 1997 Jun;55(2):278-86 [9629388.001]
  • [Cites] Acta Cytol. 1998 Sep-Oct;42(5):1104-10 [9755665.001]
  • [Cites] Neurol Med Chir (Tokyo). 1998 Aug;38(8):489-98 [9780648.001]
  • [Cites] Blood. 1998 Nov 1;92(9):3388-93 [9787178.001]
  • [Cites] Mod Pathol. 1998 Oct;11(10):999-1004 [9796730.001]
  • [Cites] Ophthalmic Genet. 1998 Sep;19(3):123-30 [9810567.001]
  • [Cites] Neurochirurgie. 1998 Nov;44(4):258-66 [9864697.001]
  • [Cites] Changgeng Yi Xue Za Zhi. 1998 Dec;21(4):503-8 [10074742.001]
  • [Cites] Arch Ophthalmol. 1999 Mar;117(3):371-8 [10088816.001]
  • [Cites] Arch Ophthalmol. 1999 May;117(5):625-30 [10326959.001]
  • [Cites] Arch Pathol Lab Med. 2003 Sep;127(9):e382-4 [12946211.001]
  • [Cites] Clin Neuropathol. 2000 May-Jun;19(3):131-7 [14606586.001]
  • [Cites] Cancer Res. 2003 Nov 1;63(21):7051-5 [14612494.001]
  • [Cites] Neurol India. 2003 Sep;51(3):373-5 [14652443.001]
  • [Cites] No Shinkei Geka. 2004 Mar;32(3):263-8 [15148801.001]
  • [Cites] J Neurosurg Spine. 2004 Jul;1(1):142 [15291036.001]
  • [Cites] Cancer. 1973 Jun;31(6):1528-40 [4736269.001]
  • [Cites] Arch Neurol. 1976 Jun;33(6):435-41 [945725.001]
  • [Cites] Neuroradiology. 1979 Apr 26;17(4):201-5 [571969.001]
  • [Cites] Acta Neuropathol. 1979 Jul 13;47(2):99-104 [573044.001]
  • [Cites] Acta Neuropathol. 1981;54(3):173-81 [7020324.001]
  • [Cites] No To Shinkei. 1983 Dec;35(12):1207-16 [6367779.001]
  • [Cites] J Comput Assist Tomogr. 1984 Dec;8(6):1175-8 [6542112.001]
  • [Cites] Acta Neuropathol. 1987;73(4):370-8 [3113168.001]
  • [Cites] Clin Neuropathol. 1987 Jul-Aug;6(4):149-54 [3308266.001]
  • [Cites] Gac Med Mex. 1988 Mar-Apr;124(3-4):131-3 [3209045.001]
  • [Cites] Am J Pathol. 1989 Feb;134(2):271-5 [2916647.001]
  • [Cites] J Clin Invest. 1996 Jun 15;97(12):2823-32 [8675694.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Jun 1;35(3):493-9 [8655372.001]
  • [Cites] Mol Med Today. 1999 Jun;5(6):257-63 [10366821.001]
  • [Cites] No Shinkei Geka. 1999 Jun;27(6):533-40 [10396736.001]
  • [Cites] Hua Xi Yi Ke Da Xue Xue Bao. 2000 Sep;31(3):380-2 [12545840.001]
  • [Cites] J Neurosurg. 1960 Jul;17:751-61 [13834086.001]
  • [Cites] AJR Am J Roentgenol. 2005 Mar;184(3 Suppl):S10-1 [15727993.001]
  • [Cites] J Chin Med Assoc. 2005 Jan;68(1):40-4 [15742863.001]
  • [Cites] Zhonghua Yi Xue Za Zhi. 2005 Jan 26;85(4):229-31 [15854481.001]
  • [Cites] Mod Pathol. 2005 Jun;18(6):788-94 [15578072.001]
  • [Cites] J Neurooncol. 2005 Jul;73(3):273-5 [15980980.001]
  • [Cites] Pathol Int. 2005 Jul;55(7):377-85 [15982211.001]
  • [Cites] Mol Vis. 2005;11:697-704 [16163267.001]
  • [Cites] Neuropathol Appl Neurobiol. 2005 Dec;31(6):618-22 [16281910.001]
  • [Cites] J Neurosurg Spine. 2005 Dec;3(6):495-500 [16381215.001]
  • [Cites] J Neurosurg. 2006 Mar;104(3):389-94 [16572651.001]
  • [Cites] Cancer Biol Ther. 2006 May;5(5):549-53 [16627978.001]
  • [Cites] J Neurosurg. 1956 Nov;13(6):641-6 [13377219.001]
  • [Cites] Acta Neuropathol. 1985;67(1-2):6-12 [4040695.001]
  • [Cites] Neurochirurgie. 1985;31(2):91-149 [3897890.001]
  • [Cites] Surg Neurol. 1986 Nov;26(5):453-6 [3764650.001]
  • [Cites] Clin Lab Med. 1987 Mar;7(1):157-79 [3030612.001]
  • [Cites] Neurosurg Rev. 1999 Oct;22(2-3):140-4 [10547017.001]
  • [Cites] Folia Neuropathol. 1999;37(3):138-42 [10581846.001]
  • [Cites] Folia Neuropathol. 1999;37(3):175-8 [10581854.001]
  • [Cites] Ultrastruct Pathol. 1999 Sep-Oct;23(5):299-310 [10582267.001]
  • [Cites] Cancer. 1999 Dec 1;86(11 Suppl):2478-82 [10630173.001]
  • [Cites] Ann Diagn Pathol. 2000 Apr;4(2):81-7 [10760321.001]
  • [Cites] Brain Tumor Pathol. 2000;17(1):15-9 [10982005.001]
  • [Cites] Bratisl Lek Listy. 2000;101(9):503-6 [11187054.001]
  • [Cites] Contrib Nephrol. 2001;(136):281-3 [11688394.001]
  • [Cites] Novartis Found Symp. 2001;240:212-25; discussion 225-31 [11727931.001]
  • [Cites] Surg Neurol. 2001 Oct;56(4):218-26; discussion 226-7 [11738662.001]
  • [Cites] Am J Dermatopathol. 2001 Oct;23(5):482-4 [11801784.001]
  • [Cites] Pathol Int. 2001 Dec;51(12):948-53 [11844068.001]
  • [Cites] Cancer Genet Cytogenet. 2002 Mar;133(2):174-8 [11943349.001]
  • [Cites] Endocr J. 2002 Apr;49(2):181-8 [12081237.001]
  • [Cites] Optom Vis Sci. 2002 Jun;79(6):346-52 [12086300.001]
  • [Cites] Chin Med J (Engl). 2002 Jul;115(7):1010-3 [12150732.001]
  • [Cites] Invest Ophthalmol Vis Sci. 2002 Sep;43(9):3067-74 [12202531.001]
  • [Cites] J Reprod Med. 2002 Oct;47(10):864-6 [12418073.001]
  • [Cites] Am J Hematol. 2002 Dec;71(4):346-7 [12447970.001]
  • [Cites] J Neurooncol. 2003 Jan;61(1):27-34 [12587793.001]
  • [Cites] Vet Pathol. 2003 Jan;40(1):91-4 [12627718.001]
  • [Cites] EMBO J. 2003 Apr 15;22(8):1857-67 [12682018.001]
  • [Cites] J Neurosurg. 2003 Apr;98(4):934-5; author reply 935 [12691428.001]
  • [Cites] Neurol India. 2003 Mar;51(1):67-8 [12865521.001]
  • [Cites] Am J Surg Pathol. 2003 Aug;27(8):1152-6 [12883249.001]
  • [Cites] Ophthal Plast Reconstr Surg. 2003 May;19(3):248-50 [12918567.001]
  • [Cites] Neurosurgery. 1989 Nov;25(5):695-8 [2586723.001]
  • [Cites] Neurol Med Chir (Tokyo). 1990 Jun;30(6):371-6 [1700315.001]
  • [Cites] Am J Surg Pathol. 1991 Jan;15(1):81-6 [1898683.001]
  • [Cites] No Shinkei Geka. 1991 Feb;19(2):149-55 [2023671.001]
  • [Cites] Neurosurgery. 1991 Jul;29(1):34-7 [1870685.001]
  • [Cites] Ophthalmology. 1992 Jan;99(1):140-5 [1741127.001]
  • [Cites] Hum Pathol. 1992 Jul;23(7):805-10 [1351864.001]
  • [Cites] Hua Xi Yi Ke Da Xue Xue Bao. 1993 Mar;24(1):9-12 [8340101.001]
  • [Cites] Biochem Biophys Res Commun. 1993 Jul 30;194(2):749-55 [7688226.001]
  • [Cites] Neurol Med Chir (Tokyo). 1993 Jul;33(7):420-4 [7692317.001]
  • [Cites] Neurosurgery. 1995 Jan;36(1):198-200; discussion 200-1 [7708160.001]
  • [Cites] Neurosurgery. 1995 Mar;36(3):573-80; discussion 580-1 [7753357.001]
  • [Cites] Chin Med J (Engl). 1995 Feb;108(2):117-22 [7774385.001]
  • [Cites] J Neuropathol Exp Neurol. 1995 Nov;54(6):842-51 [7595657.001]
  • [Cites] Am J Pathol. 1996 Feb;148(2):367-73 [8579099.001]
  • (PMID = 17877533.001).
  • [ISSN] 0959-9673
  • [Journal-full-title] International journal of experimental pathology
  • [ISO-abbreviation] Int J Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
  • [Number-of-references] 99
  • [Other-IDs] NLM/ PMC2517334
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79. Mullally WJ, Hall KE: Hypnic headache secondary to haemangioblastoma of the cerebellum. Cephalalgia; 2010 Jul;30(7):887-9
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  • [Title] Hypnic headache secondary to haemangioblastoma of the cerebellum.
  • We report a case of secondary hypnic headache in a patient with a haemangioblastoma of the cerebellum.
  • [MeSH-major] Cerebellar Neoplasms / complications. Headache Disorders, Primary / etiology. Hemangioblastoma / complications

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  • (PMID = 20647180.001).
  • [ISSN] 1468-2982
  • [Journal-full-title] Cephalalgia : an international journal of headache
  • [ISO-abbreviation] Cephalalgia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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80. Sergides IG, Wainwright KL, Biggs M: Incidental hemangioblastoma of the filum terminale. Acta Neurol Belg; 2009 Mar;109(1):55-6
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  • [Title] Incidental hemangioblastoma of the filum terminale.
  • Filum terminale hemangioblastoma is an extremely rare tumour with only a few case reports in the literature.
  • [MeSH-major] Cauda Equina / pathology. Cerebellar Neoplasms / diagnosis. Hemangioblastoma / diagnosis

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  • (PMID = 19402577.001).
  • [ISSN] 0300-9009
  • [Journal-full-title] Acta neurologica Belgica
  • [ISO-abbreviation] Acta Neurol Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
  • [Chemical-registry-number] AU0V1LM3JT / Gadolinium
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81. Mao RJ, Li QM, Guo YM, Li WQ, Fan CS, Zhu XZ: [Clinicopathologic study of giant cell angioblastoma]. Zhonghua Bing Li Xue Za Zhi; 2010 Nov;39(11):752-6
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  • [Title] [Clinicopathologic study of giant cell angioblastoma].
  • OBJECTIVE: to study the clinicopathological features, imaging characteristics, immunophenotypes and differential diagnosis of giant cell angioblastoma (GCAB).
  • A concentric arrangement of oval-to-spindle Cells around small-caliber vascular structures together with collagen fiber contributed to a so-called 'onion-skin' arrangement.
  • CONCLUSION: GCAB is a rare, locally infiltrative but slow growing neoplastic angiogenesis with unique morphological characteristics during infancy, which may occur not only in the skin, mucosa, subcutis and deep soft tissue but also in the bone.
  • [MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / pathology. Hemangioblastoma / pathology. Tibia
  • [MeSH-minor] Actins / metabolism. Antigens, CD / metabolism. Antigens, CD31 / metabolism. Antigens, CD34 / metabolism. Antigens, Differentiation, Myelomonocytic / metabolism. Dermatofibrosarcoma / metabolism. Dermatofibrosarcoma / pathology. Diagnosis, Differential. Fibula. Hemangioendothelioma / metabolism. Hemangioendothelioma / pathology. Hemangioendothelioma, Epithelioid / metabolism. Hemangioendothelioma, Epithelioid / pathology. Hemangioma, Cavernous / metabolism. Hemangioma, Cavernous / pathology. Humans. Infant. Kasabach-Merritt Syndrome. Male. Sarcoma, Kaposi / metabolism. Sarcoma, Kaposi / pathology. Skin Neoplasms / metabolism. Skin Neoplasms / pathology. Thrombocytopenia / metabolism. Thrombocytopenia / pathology. Tomography, X-Ray Computed. Vascular Neoplasms / metabolism. Vascular Neoplasms / pathology. Vimentin / metabolism

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  • (PMID = 21215166.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Antigens, CD; 0 / Antigens, CD31; 0 / Antigens, CD34; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Vimentin; Kaposiform Hemangioendothelioma
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82. Park SH, Min HS, Kim B, Myung J, Paek SH: Galectin-3: a useful biomarker for differential diagnosis of brain tumors. Neuropathology; 2008 Oct;28(5):497-506
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  • It showed consistent and diffuse positivity in 100% of the pilocytic astrocytomas, pleomorphic xanthoastrocytomas (PXA), Schwannomas, meningiomas, capillary hemangioblastomas, as well as in ependymomas, but it was completely negative in the diffuse astrocytomas, anaplastic astrocytomas, both low- and high-grades of the oligodendrogliomas, central neurocytomas, and medulloblastomas.

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  • (PMID = 18384511.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Galectin 3
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83. MacFarlane MR, Burn PJ, Evison J: Excision of high and mid cervical spinal cord arteriovenous malformations by anterior operation. J Clin Neurosci; 2005 Jan;12(1):71-9
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  • Anterior approaches have been recently described for treatment of anteriorly placed cervical arteriovenous fistulas (AVFs) and an intramedullary haemangioblastoma, but not as yet for spinal AVMs.

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  • (PMID = 15639418.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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84. Chan CC, Collins AB, Chew EY: Molecular pathology of eyes with von Hippel-Lindau (VHL) Disease: a review. Retina; 2007 Jan;27(1):1-7
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  • [Title] Molecular pathology of eyes with von Hippel-Lindau (VHL) Disease: a review.
  • BACKGROUND: von Hippel-Lindau Disease (VHL) is an autosomal dominant inherited systemic cancer syndrome.
  • RESULTS: Loss of heterozygosity (LOH) within the VHL gene is detected in the stromal cells surrounding the capillary endothelial cells and admixed with glial cells in ocular hemangioblastomas.
  • This finding is in line with similar findings in VHL-associated CNS hemangioblastoma and renal clear cell carcinomas.
  • Increases of vascular endothelial growth factor (VEGF), hypoxia induced factor (HIF), and ubiquitin are found in ocular hemangioblastomas.Interestingly, tumorlet cells, which are composed of poorly differentiated small cells with prominent dark nuclei and little cytoplasm, as well as several stem cell markers, such as erythropoietin (Epo), Epo receptor (EpoR), and CD133, are present in ocular VHL lesions.
  • CXCR4, a CXC chemokine receptor is also expressed in retinal VHL hemangioblastomas.
  • Targeting these proteins and ischemic factors, not VEGF alone, may be a potential therapeutic approach for VHL-associated ocular hemangioblastomas.
  • [MeSH-major] Hemangioblastoma / pathology. Optic Nerve Neoplasms / pathology. Retinal Neoplasms / pathology. von Hippel-Lindau Disease / pathology
  • [MeSH-minor] Genes, Tumor Suppressor / physiology. Humans. Loss of Heterozygosity. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • [Cites] Graefes Arch Clin Exp Ophthalmol. 2004 Oct;242(10):881-6 [15052488.001]
  • [Cites] Clin Cancer Res. 2005 Feb 1;11(3):1059-64 [15709172.001]
  • [Cites] Trans Am Ophthalmol Soc. 2004;102:75-9; discussion 79-81 [15747747.001]
  • [Cites] J Neurosurg. 2005 Mar;102(3):503-12 [15796386.001]
  • [Cites] EMBO Rep. 2005 Apr;6(4):373-8 [15776016.001]
  • [Cites] Anticancer Res. 2005 Mar-Apr;25(2A):1109-13 [15868953.001]
  • [Cites] J Clin Endocrinol Metab. 2005 Jun;90(6):3747-51 [15769989.001]
  • [Cites] Stem Cells. 2005 Jun-Jul;23(6):791-804 [15917475.001]
  • [Cites] Optometry. 2005 Aug;76(8):442-9 [16150411.001]
  • [Cites] Mol Vis. 2005;11:697-704 [16163267.001]
  • [Cites] Am J Physiol Cell Physiol. 2006 Jan;290(1):C172-82 [16148030.001]
  • [Cites] Blood. 2006 Mar 1;107(5):2162-9 [16269619.001]
  • [Cites] Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2528-34 [16399861.001]
  • [Cites] Trans Am Ophthalmol Soc. 2005;103:495-511 [17057815.001]
  • [Cites] Ophthalmology. 2007 Jan;114(1):147-56 [17070589.001]
  • [Cites] Ophthalmology. 2000 Dec;107(12):2240-8 [11097604.001]
  • [Cites] Adv Cancer Res. 2001;82:85-105 [11447766.001]
  • [Cites] Surv Ophthalmol. 2001 Sep-Oct;46(2):117-42 [11578646.001]
  • [Cites] Invest Ophthalmol Vis Sci. 2002 Sep;43(9):3067-74 [12202531.001]
  • [Cites] Nat Rev Cancer. 2002 Sep;2(9):673-82 [12209156.001]
  • [Cites] Ophthalmology. 2002 Sep;109(9):1745-51 [12208726.001]
  • [Cites] Semin Oncol. 2002 Dec;29(6 Suppl 19):47-52 [12577244.001]
  • [Cites] Crit Rev Oncol Hematol. 2003 Feb;45(2):177-90 [12604128.001]
  • [Cites] Mol Endocrinol. 2003 May;17(5):792-803 [12586845.001]
  • [Cites] Lancet. 2003 Jun 14;361(9374):2059-67 [12814730.001]
  • [Cites] Carcinogenesis. 2003 Jun;24(6):1021-9 [12807756.001]
  • [Cites] Am J Ophthalmol. 2003 Jul;136(1):194-6 [12834696.001]
  • [Cites] Nature. 2003 Sep 18;425(6955):307-11 [13679920.001]
  • [Cites] J Am Soc Nephrol. 2003 Nov;14(11):2695-702 [14569078.001]
  • [Cites] Cancer Res. 2003 Nov 1;63(21):7051-5 [14612494.001]
  • [Cites] JAMA. 2004 Feb 25;291(8):943-4 [14982909.001]
  • [Cites] Semin Cancer Biol. 2004 Apr;14(2):123-30 [15018896.001]
  • [Cites] Ann Neurol. 2004 May;55(5):721-8 [15122713.001]
  • [Cites] Am J Ophthalmol. 1968 Oct;66(4):693-705 [4891878.001]
  • [Cites] Proc Natl Acad Sci U S A. 1971 Apr;68(4):820-3 [5279523.001]
  • [Cites] Trans Am Ophthalmol Soc. 1970;68:367-424 [5535648.001]
  • [Cites] Am J Ophthalmol. 1976 Aug;82(2):193-204 [986118.001]
  • [Cites] Ophthalmology. 1983 Nov;90(11):1292-300 [6664668.001]
  • [Cites] Nature. 1988 Mar 17;332(6161):268-9 [2894613.001]
  • [Cites] Ophthalmology. 1992 Jan;99(1):140-5 [1741127.001]
  • [Cites] Blood. 1993 May 1;81(9):2223-36 [8481505.001]
  • [Cites] Science. 1993 May 28;260(5112):1317-20 [8493574.001]
  • [Cites] Hum Pathol. 1994 Nov;25(11):1249-51 [7959672.001]
  • [Cites] Cancer Res. 1995 Mar 15;55(6):1358-64 [7533661.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10595-9 [8855223.001]
  • [Cites] Hum Mutat. 1996;8(4):348-57 [8956040.001]
  • [Cites] Hum Pathol. 1997 May;28(5):540-3 [9158701.001]
  • [Cites] Mol Cell Biol. 1997 Sep;17(9):5629-39 [9271438.001]
  • [Cites] Medicine (Baltimore). 1997 Nov;76(6):381-91 [9413424.001]
  • [Cites] Leuk Lymphoma. 1998 Aug;30(5-6):459-66 [9711908.001]
  • [Cites] Blood. 1998 Nov 1;92(9):3388-93 [9787178.001]
  • [Cites] Arch Ophthalmol. 1999 Mar;117(3):371-8 [10088816.001]
  • [Cites] Cancer Res. 1999 May 1;59(9):2251-3 [10232616.001]
  • [Cites] Arch Ophthalmol. 1999 May;117(5):625-30 [10326959.001]
  • [Cites] Graefes Arch Clin Exp Ophthalmol. 1999 Jun;237(6):513-7 [10379614.001]
  • (PMID = 17218907.001).
  • [ISSN] 0275-004X
  • [Journal-full-title] Retina (Philadelphia, Pa.)
  • [ISO-abbreviation] Retina (Philadelphia, Pa.)
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 EY000222-22; United States / Intramural NIH HHS / / Z99 EY999999
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Review
  • [Publication-country] United States
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
  • [Number-of-references] 56
  • [Other-IDs] NLM/ NIHMS22186; NLM/ PMC1971131
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85. Chacon-Camacho OF, Rodriguez-Dennen F, Camacho-Molina A, Rasmussen A, Alonso-Vilatela E, Zenteno JC: Clinical and molecular features of familial and sporadic cases of von Hippel-Lindau disease from Mexico. Clin Exp Ophthalmol; 2010 Apr;38(3):277-83
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  • [Title] Clinical and molecular features of familial and sporadic cases of von Hippel-Lindau disease from Mexico.
  • BACKGROUND: von Hippel-Lindau disease (VHL) is an uncommon autosomal dominant condition predisposing to the development of tumours in a variety of body organs and caused by germline mutations in VHL, a tumour suppressor gene located on 3p.
  • Up to 60% of VHL patients show ocular involvement with retinal hemangioblastoma being the most common observed lesion.
  • Affected subjects from family #1 had a c.245G > C change, predicting a p.R82P substitution, affected individuals from family #2 were shown to have a c.266T > C change, leading to a p.L89P missense substitution, whereas the apparently non-familial case had a c.298-299insA mutation.
  • No ocular anomalies were found in two adult affected subjects carrying the p.L89P mutation.
  • CONCLUSION: Considerable interfamilial and intrafamilial clinical variability as well as one instance of non penetrance were recorded in these VHL disease cases.
  • [MeSH-major] Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics

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  • (PMID = 20447124.001).
  • [ISSN] 1442-9071
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  • [Chemical-registry-number] 5Z93L87A1R / Guanine; 8J337D1HZY / Cytosine; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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86. Lehman NL: The ubiquitin proteasome system in neuropathology. Acta Neuropathol; 2009 Sep;118(3):329-47
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  • In neuropathology, alteration of the UPS, or mutations in UPS target proteins may result in signaling abnormalities leading to the initiation or progression of tumors such as astrocytomas, hemangioblastomas, craniopharyngiomas, pituitary adenomas, and medulloblastomas.
  • In neurodegenerative diseases caused by the expression of mutant proteins, the cellular accumulation of these proteins may overload the UPS, indirectly contributing to the disease process, e.g., sporadic Parkinsonism and prion diseases.

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  • [Cites] Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4106-11 [17360485.001]
  • [Cites] Nature. 2009 May 28;459(7246):569-73 [19404257.001]
  • [Cites] Mol Cell. 2007 Apr 27;26(2):175-88 [17466621.001]
  • [Cites] Cell. 1999 Mar 5;96(5):635-44 [10089879.001]
  • [Cites] Clin Cancer Res. 2008 Sep 1;14(17):5416-25 [18765533.001]
  • [Cites] Am J Pathol. 2002 Dec;161(6):1997-2001 [12466115.001]
  • [Cites] J Neurosci. 2004 Sep 29;24(39):8410-5 [15456813.001]
  • [Cites] Cell Cycle. 2006 Jul;5(14):1569-73 [16861914.001]
  • [Cites] FASEB J. 2009 Sep;23(9):2820-30 [19369384.001]
  • [Cites] Neuron. 2005 Sep 1;47(5):629-32 [16129392.001]
  • [Cites] Nat Rev Cancer. 2002 Sep;2(9):673-82 [12209156.001]
  • [Cites] Science. 2004 Feb 13;303(5660):1026-30 [14716021.001]
  • [Cites] Curr Top Dev Biol. 2006;76:89-101 [17118264.001]
  • [Cites] J Biol Chem. 2008 Feb 8;283(6):3316-28 [18070888.001]
  • [Cites] Annu Rev Biochem. 1998;67:425-79 [9759494.001]
  • [Cites] J Biol Chem. 2000 Aug 18;275(33):25733-41 [10823831.001]
  • [Cites] Ann Neurol. 2007 May;61(5):427-34 [17469116.001]
  • [Cites] Blood. 2007 Nov 15;110(10):3557-60 [17690257.001]
  • [Cites] J Biol Chem. 2004 Mar 26;279(13):12876-82 [14709552.001]
  • [Cites] J Biol Chem. 1992 Dec 5;267(34):24315-21 [1447181.001]
  • [Cites] Neurochem Int. 2007 Jul-Sep;51(2-4):105-11 [17586089.001]
  • [Cites] Cell Div. 2008 Apr 22;3:8 [18430235.001]
  • [Cites] J Clin Invest. 2007 Dec;117(12):3940-51 [17992259.001]
  • [Cites] Neuron. 2003 Mar 6;37(5):735-49 [12628165.001]
  • [Cites] Curr Biol. 1999 Feb 25;9(4):207-10 [10074433.001]
  • [Cites] J Neurochem. 2008 Dec;107(6):1471-81 [19094054.001]
  • [Cites] Toxicol Pathol. 2008 Feb;36(2):345-52 [18362199.001]
  • [Cites] J Biol Chem. 2000 Mar 24;275(12):8929-35 [10722740.001]
  • [Cites] Cell Signal. 2008 Oct;20(10):1725-39 [18602463.001]
  • [Cites] Acta Neuropathol. 2000 Jul;100(1):43-9 [10912919.001]
  • [Cites] Oncogene. 2004 Mar 25;23(13):2408-19 [14743209.001]
  • [Cites] J Child Neurol. 2008 Aug;23(8):912-5 [18487518.001]
  • [Cites] J Biol Chem. 2003 Jun 13;278(24):21323-6 [12719435.001]
  • [Cites] Cancer Genet Cytogenet. 2006 Apr 1;166(1):74-81 [16616114.001]
  • [Cites] Nat Neurosci. 2009 Jun;12(6):777-83 [19430469.001]
  • [Cites] J Biol Chem. 2002 Feb 15;277(7):5484-9 [11729185.001]
  • [Cites] Annu Rev Pharmacol Toxicol. 2009;49:73-96 [18834306.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2008 Oct;79(10):1186-9 [18796596.001]
  • [Cites] J Biol Chem. 2004 Oct 1;279(40):42290-301 [15280365.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2007 Jun;78(6):626-8 [17210620.001]
  • [Cites] Mol Cancer Res. 2006 Oct;4(10):695-707 [17050664.001]
  • [Cites] Hum Mol Genet. 2008 Dec 15;17(24):3942-52 [18784277.001]
  • [Cites] PLoS One. 2009;4(3):e4973 [19319192.001]
  • [Cites] Acta Neuropathol. 2005 Jun;109(6):589-97 [15891929.001]
  • [Cites] J Cell Sci. 2004 Jan 15;117(Pt 2):281-92 [14657277.001]
  • [Cites] Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2629-34 [19196987.001]
  • [Cites] Neurobiol Dis. 2005 Dec;20(3):646-55 [15936949.001]
  • [Cites] Trends Cell Biol. 2000 Dec;10(12):524-30 [11121744.001]
  • [Cites] J Cell Biol. 2008 Mar 24;180(6):1177-89 [18362179.001]
  • [Cites] Oncogene. 2008 Oct 9;27(46):6002-11 [18574468.001]
  • [Cites] J Neurochem. 2005 Mar;92(6):1531-41 [15748170.001]
  • [Cites] J Mol Biol. 2006 Mar 3;356(4):1027-35 [16405905.001]
  • [Cites] Cell Mol Life Sci. 2007 Mar;64(5):601-9 [17256086.001]
  • [Cites] Acta Neuropathol. 2008 Aug;116(2):159-67 [18553091.001]
  • [Cites] Cancer Res. 2009 Mar 15;69(6):2314-23 [19276349.001]
  • [Cites] Neurology. 2006 Sep 26;67(6):1074-7 [16807408.001]
  • [Cites] J Biol Chem. 2009 Feb 20;284(8):5030-41 [19098288.001]
  • [Cites] Neurosci Lett. 2008 Jan 31;431(2):141-5 [18191026.001]
  • [Cites] Cell. 2001 Jun 1;105(5):645-55 [11389834.001]
  • [Cites] Hum Mutat. 2000 Jul;16(1):89-90 [10874314.001]
  • [Cites] Appl Immunohistochem Mol Morphol. 2008 May;16(3):274-8 [18301241.001]
  • [Cites] Mol Biol Cell. 2003 Jul;14(7):2809-17 [12857866.001]
  • [Cites] EMBO J. 2009 Feb 18;28(4):372-82 [19153604.001]
  • [Cites] J Neuropathol Exp Neurol. 2007 Feb;66(2):152-7 [17279000.001]
  • [Cites] Arch Neurol. 2008 Aug;65(8):1031-8 [18695053.001]
  • [Cites] FASEB J. 2008 Nov;22(11):3785-94 [18632848.001]
  • [Cites] Hum Mol Genet. 2008 Mar 15;17(6):906-17 [18065497.001]
  • [Cites] Am J Pathol. 2007 May;170(5):1793-805 [17456782.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5500-5 [15064394.001]
  • [Cites] J Neurosci. 2008 Dec 3;28(49):13285-95 [19052220.001]
  • [Cites] Genes Dev. 2006 Sep 1;20(17):2410-20 [16921029.001]
  • [Cites] PLoS Genet. 2009 Feb;5(2):e1000382 [19214209.001]
  • [Cites] Hum Mol Genet. 2001 May 15;10(11):1201-13 [11371513.001]
  • [Cites] Cancer Res. 2008 Dec 15;68(24):10094-104 [19074875.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2439-44 [10051661.001]
  • [Cites] J Biol Chem. 2005 Nov 18;280(46):38851-61 [16157591.001]
  • [Cites] Mol Cell Biol. 2007 Nov;27(22):7955-65 [17875940.001]
  • [Cites] J Alzheimers Dis. 2009;17(2):319-25 [19363271.001]
  • [Cites] J Biol Chem. 2009 Apr 10;284(15):9796-803 [19218238.001]
  • [Cites] Oncogene. 2006 Jan 5;25(1):1-7 [16278683.001]
  • [Cites] Hum Mol Genet. 2009 Apr 15;18(8):1384-94 [19168853.001]
  • [Cites] Hum Mol Genet. 2008 Oct 15;17(20):3223-35 [18658163.001]
  • [Cites] Trends Cell Biol. 2002 May;12(5):216-21 [12062168.001]
  • [Cites] Nature. 2005 Nov 10;438(7065):224-8 [16227972.001]
  • [Cites] Neurobiol Dis. 2009 Jul;35(1):32-41 [19348945.001]
  • [Cites] Nat Struct Mol Biol. 2008 Dec;15(12):1334-42 [19043414.001]
  • [Cites] Cancer Chemother Pharmacol. 2000;45(2):142-8 [10663629.001]
  • [Cites] Biochem Biophys Res Commun. 2009 Jun 5;383(3):331-5 [19358826.001]
  • [Cites] Cell Signal. 2007 Mar;19(3):573-81 [17005371.001]
  • [Cites] Biochem J. 2009 Mar 15;418(3):643-50 [19049493.001]
  • [Cites] J Exp Med. 1996 Apr 1;183(4):1545-52 [8666912.001]
  • [Cites] Eur J Neurol. 2008 Aug;15(8):772-80 [18684309.001]
  • [Cites] Methods Enzymol. 2005;399:334-55 [16338367.001]
  • [Cites] Mol Cell. 2009 May 15;34(3):259-69 [19450525.001]
  • [Cites] Acta Neuropathol. 2008 Aug;116(2):147-57 [18536926.001]
  • [Cites] Drug News Perspect. 2007 Jul-Aug;20(6):365-70 [17925890.001]
  • [Cites] PLoS Genet. 2009 Feb;5(2):e1000383 [19214206.001]
  • [Cites] Cancer Res. 2004 May 1;64(9):3103-11 [15126347.001]
  • [Cites] J Neurochem. 2008 Jul;106(1):107-20 [18346206.001]
  • [Cites] Autophagy. 2008 Apr;4(3):372-4 [18216494.001]
  • [Cites] Biochemistry. 2007 Dec 25;46(51):14889-98 [18044963.001]
  • [Cites] J Pathol. 2003 Feb;199(2):259-66 [12533840.001]
  • [Cites] J Biol Chem. 1996 May 10;271(19):11339-46 [8626687.001]
  • [Cites] Neuron. 2003 Jul 17;39(2):217-25 [12873380.001]
  • [Cites] J Neurochem. 2004 Jul;90(2):379-91 [15228595.001]
  • [Cites] J Neuropathol Exp Neurol. 2007 Oct;66(10):884-91 [17917582.001]
  • [Cites] Mod Pathol. 2000 Apr;13(4):420-6 [10786809.001]
  • [Cites] Science. 2002 Jul 19;297(5580):365-9 [12130776.001]
  • [Cites] Nat Cell Biol. 2002 May;4(5):358-66 [11988738.001]
  • [Cites] Hum Mol Genet. 2005 Apr 15;14(8):1049-58 [15757975.001]
  • [Cites] J Biol Chem. 2009 Jan 30;284(5):3250-63 [19033443.001]
  • [Cites] Mol Cell Biol. 2005 Apr;25(7):2795-807 [15767683.001]
  • [Cites] FEBS J. 2009 Mar;276(5):1208-20 [19175675.001]
  • [Cites] Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15690-5 [18836078.001]
  • [Cites] ScientificWorldJournal. 2008;8:421-33 [18454252.001]
  • [Cites] Acta Neuropathol. 2008 Dec;116(6):639-46 [18936941.001]
  • [Cites] J Biol Chem. 1982 Mar 10;257(5):2543-8 [6277905.001]
  • [Cites] J Biol Chem. 2002 Aug 9;277(32):28530-6 [12032152.001]
  • [Cites] Nature. 2004 Oct 14;431(7010):805-10 [15483602.001]
  • [Cites] Exp Neurol. 2007 Feb;203(2):531-41 [17097639.001]
  • [Cites] EMBO J. 1998 Jan 2;17(1):61-70 [9427741.001]
  • [Cites] Nat Rev Cancer. 2006 Mar;6(3):184-92 [16453012.001]
  • [Cites] Dev Cell. 2003 Jun;4(6):799-812 [12791266.001]
  • [Cites] J Biol Chem. 2005 Sep 9;280(36):32026-34 [16040601.001]
  • [Cites] Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2897-902 [19196961.001]
  • [Cites] Eur J Neurosci. 2008 Nov;28(10):1980-8 [19046380.001]
  • [Cites] Mol Cell Proteomics. 2008 Nov;7(11):2107-22 [18565875.001]
  • [Cites] Mol Biol Cell. 2006 Nov;17(11):4606-18 [16914519.001]
  • [Cites] Cell. 2009 May 15;137(4):609-22 [19450511.001]
  • [Cites] J Immunol. 1995 Oct 15;155(8):3750-8 [7561079.001]
  • [Cites] Nature. 2007 Aug 9;448(7154):704-8 [17687326.001]
  • [Cites] Science. 2001 Oct 5;294(5540):173-7 [11533444.001]
  • [Cites] Mol Cell Neurosci. 2002 Jun;20(2):298-306 [12093161.001]
  • [Cites] Mol Cell Biol. 2008 Sep;28(17):5275-87 [18573876.001]
  • [Cites] J Cell Biol. 2003 Oct 13;163(1):27-33 [14557245.001]
  • [Cites] Neuron. 2004 Nov 18;44(4):601-7 [15541309.001]
  • [Cites] J Neurosci. 2008 Jul 2;28(27):6926-37 [18596167.001]
  • [Cites] Genes Dev. 2006 Sep 15;20(18):2539-51 [16980583.001]
  • [Cites] J Clin Invest. 2009 Mar;119(3):650-60 [19229105.001]
  • [Cites] Mol Biol Cell. 2007 Apr;18(4):1129-42 [17229889.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):16041-6 [14668431.001]
  • [Cites] J Biol Chem. 2009 Mar 20;284(12):8083-92 [19112176.001]
  • [Cites] Mol Cancer Ther. 2009 Apr;8(4):930-9 [19372566.001]
  • [Cites] Acta Neuropathol. 2008 Dec;116(6):625-37 [18843496.001]
  • [Cites] Cancer Res. 2002 Oct 15;62(20):5906-11 [12384556.001]
  • [Cites] Nat Rev Neurosci. 2008 Nov;9(11):826-38 [18931696.001]
  • [Cites] Annu Rev Immunol. 2004;22:81-127 [15032575.001]
  • [Cites] J Biol Chem. 2008 Mar 21;283(12):7648-56 [18201976.001]
  • (PMID = 19597829.001).
  • [ISSN] 1432-0533
  • [Journal-full-title] Acta neuropathologica
  • [ISO-abbreviation] Acta Neuropathol.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / K08 NS045077
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ubiquitin; EC 3.4.25.1 / Proteasome Endopeptidase Complex
  • [Number-of-references] 149
  • [Other-IDs] NLM/ PMC2716447
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87. Cheshier SH, Hanft SJ, Adler JR, Chang SD: CyberKnife radiosurgery for lesions of the foramen magnum. Technol Cancer Res Treat; 2007 Aug;6(4):329-36
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  • Histologies were determined either by prior surgery or radiographic criteria and included 25 benign tumors (nine meningiomas, five schwannomas, four neurofibromas, three hemangioblastomas, two ependymomas, one chordomas, and one pilocytic astrocytoma) along with 10 malignant growths (nine metastases and one chondrosarcoma).
  • There were eleven (31%) deaths in our series, eight of which were related to the disease (though not directly related to CyberKnife treatment) and three of which were from unrelated causes.

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  • (PMID = 17668941.001).
  • [ISSN] 1533-0346
  • [Journal-full-title] Technology in cancer research & treatment
  • [ISO-abbreviation] Technol. Cancer Res. Treat.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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88. Lemeta S, Jarmalaite S, Pylkkänen L, Böhling T, Husgafvel-Pursiainen K: Preferential loss of the nonimprinted allele for the ZAC1 tumor suppressor gene in human capillary hemangioblastoma. J Neuropathol Exp Neurol; 2007 Sep;66(9):860-7
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  • [Title] Preferential loss of the nonimprinted allele for the ZAC1 tumor suppressor gene in human capillary hemangioblastoma.
  • Capillary hemangioblastomas (CHBs) are vascular, usually benign, tumors of the CNS, occurring either as a component of familial von Hippel-Lindau (VHL) disease or as a sporadic entity.
  • This novel finding highlights the importance of ZAC1 in development of CHB, particularly in non-VHL-associated cases.
  • [MeSH-major] Alleles. Cell Cycle Proteins / genetics. Genes, Tumor Suppressor. Genomic Imprinting. Hemangioblastoma / genetics. Transcription Factors / genetics. Tumor Suppressor Proteins / genetics. Vascular Neoplasms / genetics

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  • (PMID = 17805016.001).
  • [ISSN] 0022-3069
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / PLAGL1 protein, human; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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89. Hasselblatt M, Jeibmann A, Gerss J, Behrens C, Rama B, Wassmann H, Paulus W: Cellular and reticular variants of haemangioblastoma revisited: a clinicopathologic study of 88 cases. Neuropathol Appl Neurobiol; 2005 Dec;31(6):618-22
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  • [Title] Cellular and reticular variants of haemangioblastoma revisited: a clinicopathologic study of 88 cases.
  • The presence of histological variants of haemangioblastoma is well established, but data on the prognostic implications of histological subtyping are missing.
  • We thus characterized clinical factors associated with histological subtypes, that is, of the cellular and reticular variant of haemangioblastoma, in a series of 88 consecutive primary haemangioblastomas of the central nervous system.
  • Ten haemangioblastomas were classified as 'cellular' according to Cushing and Bailey.
  • As compared to the more common 'reticular' variant (n = 78), the proportion of tumours containing glial fibrillary acidic protein-positive tumour cells (80% vs. 7%), as well as median Ki67 (MIB1) proliferation indices [4% (quartiles: 1-8%) vs. < 1% (<1-2%)], was significantly higher in cellular haemangioblastomas (P < 0.01).
  • Cox regression analysis not only confirmed the well established association of von Hippel-Lindau disease with tumour recurrence (P < 0.01), but also revealed an independent effect of histological subtype on the probability of recurrence (P < 0.05), whereas no significant influence of age, sex or tumour location was observed.
  • To conclude, the results from this retrospective study suggest that histological subtyping of haemangioblastomas has prognostic implications and might contribute to identify patients at risk for recurrence.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Hemangioblastoma / pathology. Neoplasm Recurrence, Local / pathology. Spinal Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Risk Factors

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  • (PMID = 16281910.001).
  • [ISSN] 0305-1846
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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90. Hes FJ, van der Luijt RB, Janssen AL, Zewald RA, de Jong GJ, Lenders JW, Links TP, Luyten GP, Sijmons RH, Eussen HJ, Halley DJ, Lips CJ, Pearson PL, van den Ouweland AM, Majoor-Krakauer DF: Frequency of Von Hippel-Lindau germline mutations in classic and non-classic Von Hippel-Lindau disease identified by DNA sequencing, Southern blot analysis and multiplex ligation-dependent probe amplification. Clin Genet; 2007 Aug;72(2):122-9
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  • [Title] Frequency of Von Hippel-Lindau germline mutations in classic and non-classic Von Hippel-Lindau disease identified by DNA sequencing, Southern blot analysis and multiplex ligation-dependent probe amplification.
  • The current clinical diagnosis of Von Hippel-Lindau (VHL) disease demands at least one specific [corrected] VHL manifestation in a patient with familial VHL disease, or, in a [corrected] sporadic patient, at least two or more hemangioblastomas or a single hemangioblastoma in combination with a typical visceral lesion.
  • [MeSH-major] Gene Frequency. Germ-Line Mutation. von Hippel-Lindau Disease / diagnosis. von Hippel-Lindau Disease / genetics

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  • [ErratumIn] Clin Genet. 2008 Apr;73(4):399
  • (PMID = 17661816.001).
  • [ISSN] 0009-9163
  • [Journal-full-title] Clinical genetics
  • [ISO-abbreviation] Clin. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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91. Chen S, Sanford CA, Sun J, Choi V, Van Dyke T, Samulski RJ, Rathmell WK: VHL and PTEN loss coordinate to promote mouse liver vascular lesions. Angiogenesis; 2010 Mar;13(1):59-69
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  • Von Hippel-Lindau (VHL) inactivation develops a tumor syndrome characterized by highly vascularized tumors as a result of hypoxia inducible factors (HIF) stabilization.
  • The most common manifestation is the development of hemangioblastomas typically located in the central nervous system and other organs including the liver.
  • Vhl and Pten conditional deletion (Vhl (loxP/loxP);Pten (loxP/loxP)) mice, however, developed multiple cavernous liver lesions reminiscent of hemangioblastoma.
  • Liver hemangioblastomas in VHL disease may, therefore, require secondary mutation in addition to VHL loss of heterozygosity which is permissive for vascular lesion development or augments levels of HIF-1alpha.

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  • [Cites] Cell. 2000 Feb 18;100(4):387-90 [10693755.001]
  • [Cites] Oncogene. 2009 Apr 9;28(14):1694-705 [19252526.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1583-8 [11171994.001]
  • [Cites] Gene Ther. 2001 Aug;8(16):1248-54 [11509958.001]
  • [Cites] Int J Cancer. 2002 May 1;99(1):53-7 [11948491.001]
  • [Cites] Curr Opin Genet Dev. 2003 Feb;13(1):55-60 [12573436.001]
  • [Cites] Cancer Res. 2003 Sep 1;63(17):5320-8 [14500363.001]
  • [Cites] Gene Ther. 2003 Dec;10(26):2112-8 [14625565.001]
  • [Cites] Nephron Exp Nephrol. 2004;96(4):e119-26 [15122061.001]
  • [Cites] Clin Radiol. 1992 Jan;45(1):37-9 [1740034.001]
  • [Cites] Cancer Res. 1994 Jun 1;54(11):2852-5 [8187067.001]
  • [Cites] Nat Genet. 1994 May;7(1):85-90 [7915601.001]
  • [Cites] Cancer Res. 1995 Nov 1;55(21):4804-7 [7585510.001]
  • [Cites] Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9102-7 [9256442.001]
  • [Cites] Medicine (Baltimore). 1997 Nov;76(6):381-91 [9413424.001]
  • [Cites] J Biochem. 1997 Nov;122(5):977-82 [9443813.001]
  • [Cites] Gene Ther. 1999 Jun;6(6):973-85 [10455399.001]
  • [Cites] Cancer Res. 2004 Dec 1;64(23):8595-603 [15574766.001]
  • [Cites] Nat Genet. 2005 Jan;37(1):19-24 [15624019.001]
  • [Cites] Nature. 2005 Aug 4;436(7051):725-30 [16079851.001]
  • [Cites] Oncogene. 2005 Nov 14;24(50):7455-64 [16288292.001]
  • [Cites] J Thromb Haemost. 2005 Dec;3(12):2627-32 [15975138.001]
  • [Cites] Nat Med. 2006 Sep;12(9):1081-7 [16906157.001]
  • [Cites] Expert Rev Anticancer Ther. 2008 Jan;8(1):63-73 [18095884.001]
  • [Cites] Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2622-7 [18268343.001]
  • [Cites] Nat Cell Biol. 2008 Mar;10(3):361-9 [18297059.001]
  • [Cites] EMBO J. 2008 Jun 18;27(12):1747-57 [18497742.001]
  • [Cites] Genes Dev. 2000 Feb 15;14(4):391-6 [10691731.001]
  • (PMID = 20221685.001).
  • [ISSN] 1573-7209
  • [Journal-full-title] Angiogenesis
  • [ISO-abbreviation] Angiogenesis
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA121781-03; United States / NCI NIH HHS / CA / R01 CA121781; United States / NCI NIH HHS / CA / R01 CA121781-03; United States / NCI NIH HHS / CA / R01-CA121781
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Vascular Endothelial Growth Factor A; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 3.1.3.48 / Pten protein, mouse; EC 3.1.3.67 / PTEN Phosphohydrolase; EC 6.3.2.19 / Vhlh protein, mouse; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
  • [Other-IDs] NLM/ NIHMS195370; NLM/ PMC2872996
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92. Akil H, Statham PF, Götz M, Bramley P, Whittle IR: Adult cerebellar mutism and cognitive-affective syndrome caused by cystic hemangioblastoma. Acta Neurochir (Wien); 2006 May;148(5):597-8
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  • [Title] Adult cerebellar mutism and cognitive-affective syndrome caused by cystic hemangioblastoma.
  • In this report we present a very unusual case of pre-operative cerebellar mutism in an adult in the context of cognitive-affective syndrome caused by cystic hemangioblastoma.
  • [MeSH-major] Affective Symptoms / etiology. Cerebellar Neoplasms / psychology. Cognition Disorders / etiology. Hemangioblastoma / psychology. Mutism / etiology

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  • [CommentIn] Acta Neurochir (Wien). 2007;149(4):437; Author reply 437-8 [17426999.001]
  • (PMID = 16200477.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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93. Pipp I, Wagner L, Rössler K, Budka H, Preusser M: Secretagogin expression in tumours of the human brain and its coverings. APMIS; 2007 Apr;115(4):319-26
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  • We found focal or widespread secretagogin expression in tumour cells in 1/18 oligoastrocytomas, 1/19 oligodendrogliomas, 2/20 anaplastic oligodendrogliomas, 2/9 ependymomas, 2/11 anaplastic ependymomas, 2/10 glioblastomas, 3/11 gangliogliomas and 1/2 anaplastic gangliogliomas, 10/10 central neurocytomas, 5/10 classic medulloblastomas, 4/5 desmoplastic medulloblastomas, 3/5 large cell/anaplastic medulloblastomas, 3/5 neuroblastomas, 3/10 meningiomas, 2/10 haemangioblastomas, and 13/19 pituitary adenomas.
  • Further, we observed secretagogin expression in endothelial cells in 5/10 meningiomas, 2/5 haemangiopericytomas, and 2/10 haemangioblastomas.

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  • (PMID = 17504298.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calcium-Binding Proteins; 0 / SCGN protein, human; 0 / Secretagogins
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94. Evans DG, Birch JM, Ramsden RT, Sharif S, Baser ME: Malignant transformation and new primary tumours after therapeutic radiation for benign disease: substantial risks in certain tumour prone syndromes. J Med Genet; 2006 Apr;43(4):289-94
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  • [Title] Malignant transformation and new primary tumours after therapeutic radiation for benign disease: substantial risks in certain tumour prone syndromes.
  • This has been particularly true for benign CNS (central nervous system) tumours such as vestibular schwannoma, meningioma, pituitary adenoma, and haemangioblastoma.
  • [MeSH-minor] Basal Cell Nevus Syndrome / radiotherapy. Humans. Li-Fraumeni Syndrome / radiotherapy. Neurofibromatoses / radiotherapy. Radiotherapy / adverse effects. Retinoblastoma / radiotherapy. Risk Factors. Syndrome. von Hippel-Lindau Disease / radiotherapy

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  • [Cites] Cancer. 1986 May 15;57(10):2006-21 [3082508.001]
  • [Cites] Br J Cancer. 1986 May;53(5):661-71 [3718823.001]
  • [Cites] N Engl J Med. 1987 May 21;316(21):1289-94 [3574400.001]
  • [Cites] Br J Cancer. 1987 Sep;56(3):339-47 [2822073.001]
  • [Cites] Br J Neurosurg. 1991;5(6):643-6 [1772613.001]
  • [Cites] BMJ. 1992 May 23;304(6838):1343-6 [1611331.001]
  • [Cites] J Clin Oncol. 1993 Feb;11(2):262-70 [8426203.001]
  • [Cites] Radiology. 1993 Jun;187(3):843-6 [8497642.001]
  • [Cites] Arch Intern Med. 1996 Sep 9;156(16):1873-8 [8790083.001]
  • [Cites] Int J Radiat Biol. 1996 Aug;70(2):145-50 [8794843.001]
  • [Cites] J Med Genet. 1996 Feb;33(2):120-7 [8929948.001]
  • [Cites] Br J Cancer. 1998 Jun;77(12):2181-92 [9649131.001]
  • [Cites] Neurosurgery. 1998 Jul;43(1):28-34; discussion 34-5 [9657185.001]
  • [Cites] Minim Invasive Neurosurg. 2003 Aug;46(4):254-6 [14506573.001]
  • [Cites] Int J Cancer. 2003 Dec 10;107(5):791-6 [14566829.001]
  • [Cites] J Med Genet. 2003 Nov;40(11):802-6 [14627667.001]
  • [Cites] Can J Neurol Sci. 2003 Nov;30(4):378-83 [14672272.001]
  • [Cites] J Clin Pathol. 2004 Jan;57(1):109-10 [14693854.001]
  • [Cites] Ophthalmology. 2004 Jan;111(1):150-3 [14711727.001]
  • [Cites] Lancet. 2004 Jan 31;363(9406):345-51 [15070562.001]
  • [Cites] Stereotact Funct Neurosurg. 1998 Oct;70 Suppl 1:65-73 [9782237.001]
  • [Cites] Stereotact Funct Neurosurg. 1998 Oct;70 Suppl 1:179-86 [9782249.001]
  • [Cites] Ann Neurol. 1999 Mar;45(3):393-6 [10072056.001]
  • [Cites] J Med Genet. 1999 Mar;36(3):197-203 [10204844.001]
  • [Cites] Br J Cancer. 1999 Apr;79(11-12):1884-93 [10206309.001]
  • [Cites] J Neurosurg. 1999 May;90(5):815-22 [10223445.001]
  • [Cites] Arch Dis Child. 1999 Jan;80(1):1-3 [10325750.001]
  • [Cites] Am J Hum Genet. 1999 Sep;65(3):784-94 [10441587.001]
  • [Cites] Cancer. 1963 Aug;16:1003-14 [14050004.001]
  • [Cites] J Neurosurg. 2005 Jan;102 Suppl:195-9 [15662809.001]
  • [Cites] Br J Neurosurg. 2004 Aug;18(4):338-42 [15702831.001]
  • [Cites] Br J Neurosurg. 2005 Feb;19(1):5-12 [16147576.001]
  • [Cites] J Clin Oncol. 2006 Jun 1;24(16):2570-5 [16735710.001]
  • [Cites] N Engl J Med. 1988 Oct 20;319(16):1033-9 [3173432.001]
  • [Cites] J Pediatr. 1989 May;114(5):788-92 [2497236.001]
  • [Cites] Surgery. 1991 Oct;110(4):691-5 [1833847.001]
  • [Cites] Br J Cancer. 1991 Nov;64(5):959-61 [1931625.001]
  • [Cites] Br J Cancer. 2000 Feb;82(4):998 [10732777.001]
  • [Cites] Otolaryngol Head Neck Surg. 2000 May;122(5):667-72 [10793343.001]
  • [Cites] Am J Otol. 2000 May;21(3):364-70 [10821550.001]
  • [Cites] Surg Neurol. 2000 Apr;53(4):383-89; discussion 389-90 [10825525.001]
  • [Cites] Br J Neurosurg. 2000 Apr;14(2):93-5 [10889878.001]
  • [Cites] Acta Neurochir (Wien). 2000;142(6):641-4; discussion 644-5 [10949438.001]
  • [Cites] Cancer Invest. 1999;17(1):56-72 [10999050.001]
  • [Cites] Am J Hum Genet. 1999 Oct;65(4):995-1006 [10486318.001]
  • [Cites] Int J Cancer. 2000 Nov 15;88(4):672-8 [11058888.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Dec 1;48(5):1381-7 [11121637.001]
  • [Cites] J Natl Cancer Inst. 2001 Apr 18;93(8):618-29 [11309438.001]
  • [Cites] Clin Oncol (R Coll Radiol). 2000;12(5):300-4 [11315715.001]
  • [Cites] Int J Cancer. 2001 Aug 20;96(4):238-42 [11474498.001]
  • [Cites] Oncogene. 2001 Aug 2;20(34):4621-8 [11498785.001]
  • [Cites] J Neurosurg. 2001 Sep;95(3):518-21 [11565878.001]
  • [Cites] Radiat Res. 2002 Feb;157(2):158-65 [11835679.001]
  • [Cites] Clin Endocrinol (Oxf). 2001 Nov;55(5):613-6 [11894972.001]
  • [Cites] J Med Genet. 2002 May;39(5):311-4 [12011145.001]
  • [Cites] J Med Genet. 2002 May;39(5):315-22 [12011146.001]
  • [Cites] Arch Dis Child. 2002 Jul;87(1):65-70 [12089128.001]
  • [Cites] Lancet. 2002 Jul 27;360(9329):309-10 [12147377.001]
  • [Cites] Br J Neurosurg. 2002 Jun;16(3):284-9 [12201399.001]
  • [Cites] Brain. 2003 Jan;126(Pt 1):152-60 [12477702.001]
  • [Cites] Cancer. 2003 Feb 15;97(4):1084-92 [12569610.001]
  • [Cites] Eur J Cancer. 2003 Apr;39(6):808-17 [12651207.001]
  • [Cites] Lancet. 2003 Mar 29;361(9363):1101-2 [12672316.001]
  • [Cites] Health Phys. 2003 Jul;85(1):47-59 [12852471.001]
  • [Cites] Cancer. 2003 Aug 1;98(3):618-24 [12879481.001]
  • [Cites] Tumori. 2003 Jul-Aug;89(4 Suppl):197-9 [12903592.001]
  • [Cites] Mayo Clin Proc. 2003 Jun;78(6):708-15 [12934780.001]
  • [Cites] Oncogene. 2003 Sep 1;22(37):5774-83 [12947385.001]
  • [Cites] Cancer. 2004 May 15;100(10):2246-52 [15139071.001]
  • [Cites] Neurochirurgie. 2004 Jun;50(2-3 Pt 2):367-76 [15179291.001]
  • [Cites] JAMA. 1967 Jan 23;199(4):280-1 [4224873.001]
  • [Cites] Am J Surg. 1968 Oct;116(4):518-23 [4300240.001]
  • [Cites] Br J Ophthalmol. 1969 Dec;53(12):793-8 [5386369.001]
  • [Cites] Ann Intern Med. 1977 Aug;87(2):160-4 [889197.001]
  • [Cites] J Natl Cancer Inst. 1979 Jun;62(6):1347-59 [286106.001]
  • [Cites] Arch Dermatol. 1980 Oct;116(10):1159-63 [7425663.001]
  • [Cites] Arch Pathol Lab Med. 1983 Jun;107(6):293-7 [6687792.001]
  • (PMID = 16155191.001).
  • [ISSN] 1468-6244
  • [Journal-full-title] Journal of medical genetics
  • [ISO-abbreviation] J. Med. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 80
  • [Other-IDs] NLM/ PMC2563223
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95. Simon I, Rorive S, Kirkpatrick C, Roumeguere T, Nortier JL: Clear cell renal carcinoma presenting as a bleeding cyst in pregnancy: inaugural manifestation of a von Hippel-Lindau disease. Clin Nephrol; 2008 Mar;69(3):224-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clear cell renal carcinoma presenting as a bleeding cyst in pregnancy: inaugural manifestation of a von Hippel-Lindau disease.
  • Von Hippel-Lindau (VHL) disease is a dominant autosomal disorder inducing the development of many tumors, such as hemangioblastomas in the central nervous system and retina, cysts or tumors (benign or malignant) in the kidneys and/or the pancreas.
  • We report the case of a pregnant woman who presented with a voluminous hemorrhagic cyst of the right kidney with an exophytic lesion detected in the lower median part of the cyst wall.
  • As an anamnestic inquiry resulted in a familial history of VHL disease, a screening imaging was performed and detected three medullary hemangioblastomas.
  • This case underlines the importance of screening procedures such as abdominal ultrasonography and medullary magnetic resonance imaging in all pregnant women with a familial history of VHL disease.
  • [MeSH-major] Carcinoma, Renal Cell / complications. Hematuria / etiology. Kidney Diseases, Cystic / diagnosis. Kidney Neoplasms / complications. Pregnancy Complications, Neoplastic. von Hippel-Lindau Disease / complications


96. Basić-Jukić N, Basić-Kes V, Kes P, Furić-Cunko V, Bacić-Baronica K: [Neurological complications in renal transplant recipients]. Acta Med Croatica; 2008;62 Suppl 1:76-81
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  • Renal transplantation is method of choice for treatment of patients with end-stage renal disease without contraindications for immunosuppressive therapy.
  • CNS infections clinically present as meningitis, progressive dementia or focal neurological defect.
  • The most common primary brain tumors are B-cell lymphomas, but glioblastoma, hemangioblastoma, leiomyosarcoma or glioma may also occur.

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  • (PMID = 18578336.001).
  • [ISSN] 1330-0164
  • [Journal-full-title] Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti
  • [ISO-abbreviation] Acta Med Croatica
  • [Language] hrv
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Croatia
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
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97. Chrétien F, Djindjian M, Caramelle P, Ricolfi F, Christov C: A 42-year-old man with a densely vascular spinal mass. Brain Pathol; 2007 Jan;17(1):119-21
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  • The preoperative diagnosis was spinal hemangioblastoma.
  • Interestingly, in our case the rich malformative vasculature and the corresponding angiographic image were most compatible with descriptions of "mixed" angiogliomas.
  • [MeSH-major] Arteriovenous Malformations / pathology. Ganglioglioma / pathology. Hemangioma / pathology. Spinal Neoplasms / pathology

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  • (PMID = 17493047.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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98. Alegret A, Cebulla CM, Dubovy SR, Mutapcic L, Hess DJ, Murray TG: Photodynamic therapy and vitrectomy for a large optic nerve hemangioma with neovascularization and retinal detachment: a clinicopathologic correlation. Retin Cases Brief Rep; 2009;3(1):93-5
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  • [Title] Photodynamic therapy and vitrectomy for a large optic nerve hemangioma with neovascularization and retinal detachment: a clinicopathologic correlation.
  • PURPOSE: To report the clinicopathologic correlation of a young man with a von Hippel-Lindau disease-associated peripapillary hemangioblastoma and its satisfactory response to a combination of photodynamic therapy (PDT) and vitrectomy.
  • METHODS: We studied the case of a 14-year-old boy with an optic nerve mass and large inferior exudative retinal detachment complicated by a significant tractional component from extensive secondary neovascularization over the lesion.
  • RESULTS: A juxtapapillary hemangioblastoma with secondary neovascularization was documented by clinical examination, fundus photography, and optical coherence tomography.
  • A von Hippel-Lindau gene mutation was detected.
  • CONCLUSIONS: A staged approach to treatment of peripapillary hemangioblastoma with a combination of PDT and vitrectomy may be favorable to therapy with one modality.

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  • (PMID = 25390852.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Riesenburger RI, Hwang SW, David CA: Postoperative resolution of abnormal blood vessels related to a nerve root hemangioblastoma. South Med J; 2009 Apr;102(4):408-10
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  • [Title] Postoperative resolution of abnormal blood vessels related to a nerve root hemangioblastoma.
  • To our knowledge, there are currently no published reports that describe the postoperative evolution of abnormal blood vessels associated with spinal nerve root hemangioblastomas.
  • We present a patient with a hemangioblastoma that was completely resected.
  • We hypothesize that complete resection of spinal nerve root hemangioblastomas eliminates the venous hypertension and allows for regression of the dilated vascular network.
  • [MeSH-major] Hemangioblastoma / complications. Peripheral Nervous System Neoplasms / complications. Spinal Nerve Roots / pathology. Venous Insufficiency / etiology

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  • [CommentIn] South Med J. 2009 Apr;102(4):347-8 [19279542.001]
  • (PMID = 19279545.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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100. Gaal J, van Nederveen FH, Erlic Z, Korpershoek E, Oldenburg R, Boedeker CC, Kontny U, Neumann HP, Dinjens WN, de Krijger RR: Parasympathetic paragangliomas are part of the Von Hippel-Lindau syndrome. J Clin Endocrinol Metab; 2009 Nov;94(11):4367-71
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  • [Title] Parasympathetic paragangliomas are part of the Von Hippel-Lindau syndrome.
  • CONTEXT: Von Hippel-Lindau (VHL) disease, caused by germline mutations in the VHL gene, is a hereditary tumor syndrome manifested by hemangioblastomas, clear cell renal cell carcinomas, and pheochromocytomas.
  • In addition, a multitude of other rare tumors, including parasympathetic paragangliomas, can occur and even be the sole manifestation of VHL disease.
  • However, in parasympathetic paragangliomas occurring in VHL disease, biallelic inactivation of the VHL gene has not been demonstrated to date.
  • CONCLUSIONS: These findings indicate that parasympathetic paragangliomas in VHL disease, although rare, are part of the syndrome and related to VHL gene inactivation.
  • Clinicians should be aware of the potential occurrence of parasympathetic paragangliomas in VHL disease.
  • [MeSH-major] Paraganglioma / epidemiology. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / complications. von Hippel-Lindau Disease / genetics

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  • (PMID = 19808854.001).
  • [ISSN] 1945-7197
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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