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1. Küpeli S, Varan A, Demir H, Aydin B, Yüce A, Büyükpamukçu M: Association of Helicobacter pylori and childhood lymphoma. J Pediatr Hematol Oncol; 2007 May;29(5):301-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of Helicobacter pylori and childhood lymphoma.
  • We aimed to estimate the frequency of association between non-Hodgkin lymphoma (NHL) with abdominal, gastric, or intestinal involvement and Helicobacter pylori in childhood.
  • Pathologic diagnosis was made by examining the biopsy samples.
  • Six had stage IV characteristics, whereas another 9 patients had stage III disease.
  • Ten had high-grade B-cell lymphoma.
  • First patient had T-cell lymphoma and stage IV disease with involvement in stomach, mediastinum, peripheral lymph nodes, and bone marrow.
  • The second one had anaplastic large cell lymphoma exclusively in abdominal lymph nodes.
  • Last patient had Burkitt lymphoma and stage IV disease, with primary tumor localization in abdominal lymph nodes, liver, and kidneys.
  • Preliminary results of our study suggest that H. pylori may not be the responsible agent for NHL involved the abdomen in childhood.
  • [MeSH-major] Gastrointestinal Neoplasms / epidemiology. Helicobacter Infections / epidemiology. Helicobacter pylori / isolation & purification. Lymphoma, B-Cell / epidemiology. Lymphoma, Non-Hodgkin / epidemiology
  • [MeSH-minor] Adolescent. Anti-Bacterial Agents / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Child, Preschool. Combined Modality Therapy. Drug Therapy, Combination. Female. Humans. Male. Neoplasm Staging. Prospective Studies. Recurrence. Risk Assessment. Sampling Studies. Treatment Outcome. Turkey / epidemiology

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  • (PMID = 17483706.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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2. Cwiklińska M, Czogała M, Balwierz W, Hnatko-Kołacz M, Moryl-Bujakowska A, Malinowska I, Sładek M, Wieczorek M, Fyderek K, Matysiak M, Rygielska M, Sierhej I: [Hemophagocytic syndrome in children with different underlying conditions]. Przegl Lek; 2010;67(6):430-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In 3 cases HS was associated with infections (EBV, CMV, Bacillus Calmette Guerin - BCG), in 1 child with non-Hodgkin anaplastic large cell lymphoma (ALCL), in 1 patients probably with side effect of antiepileptic drug.
  • Among others, antibiotics, antiviral and immunosuppressive drugs were used in therapy.
  • Patient with ALCL was treated with chemotherapy and allogeneic stem cell transplantation.
  • In case of prolonged fever, splenomegaly and cytopenia diagnosis of HS should be considered.
  • Following tests are recommended: complete blood count, ferritin, triglycerides, fibrinogen, bone marrow aspiration and NK cell assessment.
  • Early diagnosis of HS and underlying condition is crucial to start lifesaving therapy.
  • [MeSH-major] Lymphohistiocytosis, Hemophagocytic / diagnosis. Lymphohistiocytosis, Hemophagocytic / etiology
  • [MeSH-minor] Adolescent. Anticonvulsants / adverse effects. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Lymphoma, Large B-Cell, Diffuse / complications. Lymphoma, Large B-Cell, Diffuse / diagnosis. Magnetic Resonance Imaging. Male. Virus Diseases / complications. Virus Diseases / diagnosis

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  • (PMID = 21344776.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Anticonvulsants
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3. Postovsky S, Bialik V, Keidar Z, Eppelman M, Militianu D, Ben Izhak OB, Ben Arush MW: Large cell lymphoma of bone presented by limp. J Pediatr Orthop B; 2001 Jan;10(1):81-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large cell lymphoma of bone presented by limp.
  • We present a rare case of anaplastic large cell lymphoma of the bone in the leg of a child.
  • Thereafter, an open biopsy of the lesion was performed and the correct diagnosis was established.
  • This rare case demonstrates the difficulties that a treating physician meets in establishing the correct diagnosis in a child presenting with limping.
  • [MeSH-major] Bone Neoplasms / diagnosis. Gait. Lymphoma, Large B-Cell, Diffuse / diagnosis
  • [MeSH-minor] Child, Preschool. Humans. Male. Osteomyelitis / diagnosis. Osteomyelitis / drug therapy. Radiopharmaceuticals. Technetium Tc 99m Medronate

  • Genetic Alliance. consumer health - Lymphoma, large-cell.
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  • (PMID = 11269818.001).
  • [ISSN] 1060-152X
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; X89XV46R07 / Technetium Tc 99m Medronate
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4. Madero L, Benito AI, Quintero V, Gonzalez-Vicent M, Díaz MA: Ki-1+ anaplastic large cell lymphoma in a child with unpredictable clinical course. Pediatr Hematol Oncol; 2001 Mar;18(2):143-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ki-1+ anaplastic large cell lymphoma in a child with unpredictable clinical course.
  • Ki-1+ anaplastic large cell lymphoma (Ki-1+ ALCL) is a subtype of non-Hodgkin lymphoma (NHL) with defined histopathological characteristics but with highly variable clinical presentation and outcome.
  • Although in most of the patients the disease behaves as an intermediate- or high-grade lymphoma, some patients present with an indolent clinical course.
  • Factors that determine the clinical behavior of this lymphoma have not yet been identified.
  • A case is reported of a 13-year-old girl who initially presented with Ki-1+ ALCL but later developed recurrent localized cutaneous disease and followed a clinical course similar to that of a low-grade lymphoma.
  • [MeSH-major] Lymphoma, Large-Cell, Anaplastic / pathology
  • [MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Diagnosis, Differential. Disease-Free Survival. Female. Humans. Lymphoma, Follicular / diagnosis. Lymphoma, Follicular / drug therapy. Lymphoma, Follicular / pathology. Neoplasm Invasiveness. Neoplasms, Second Primary / chemistry. Neoplasms, Second Primary / drug therapy. Neoplasms, Second Primary / pathology. Recurrence. Skin Neoplasms / chemistry. Skin Neoplasms / drug therapy. Skin Neoplasms / pathology

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  • (PMID = 11255733.001).
  • [ISSN] 0888-0018
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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5. Cesaro S, Pillon M, Visintin G, Putti MC, Gazzola MV, D'Amore E, Scarzello G, Zanesco L, Messina C, Rosolen A: Unrelated bone marrow transplantation for high-risk anaplastic large cell lymphoma in pediatric patients: a single center case series. Eur J Haematol; 2005 Jul;75(1):22-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unrelated bone marrow transplantation for high-risk anaplastic large cell lymphoma in pediatric patients: a single center case series.
  • OBJECTIVES: The use of allogeneic stem cell transplantation in NHL patients is not yet clearly defined, especially in children and adolescents, but this option offers the advantages of a tumor-free graft and the possible induction of a graft-vs.-tumor effect.
  • PATIENTS AND METHODS: We report the results of four consecutive pediatric patients affected by anaplastic large cell lymphoma (ALCL) and treated with allogeneic stem cell transplantation from an unrelated donor.
  • CONCLUSIONS: The increasing number of volunteer bone marrow donors and the reduced toxicity of unrelated stem cell transplantation, especially in children, make this therapeutic option worth more extensive investigation in the treatment of high-risk failure ALCL, although more data is needed to evaluate the long-term benefits.
  • In this regard, the presence of factors predictive of worst outcome such as an early relapse (within 12 months from diagnosis), a refractory or relapsing ALCL and the persistent detection on blood or bone marrow of nucleophosmin-anaplastic lymphoma kinase protein (NPM-ALK) transcript may help select the patients eligible to allogeneic related or unrelated stem cell transplantation.
  • [MeSH-major] Bone Marrow Transplantation. Lymphoma, Large B-Cell, Diffuse / therapy
  • [MeSH-minor] Adolescent. Adult. Antilymphocyte Serum / administration & dosage. Child. Child, Preschool. Cyclosporine / administration & dosage. Female. Follow-Up Studies. Graft vs Host Disease / prevention & control. Graft vs Leukemia Effect / drug effects. Graft vs Leukemia Effect / radiation effects. Histocompatibility Testing. Humans. Male. Risk Factors. Secondary Prevention. Transplantation Conditioning. Transplantation, Homologous. Whole-Body Irradiation






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