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1. Om AS, Shim JY: Effect of daidzein, a soy isoflavone, on bone metabolism in Cd-treated ovariectomized rats. Acta Biochim Pol; 2007;54(3):641-6
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  • All rats were given free access to AIN-76 modified diet and drinking water, with or without Cd, for 8 weeks.

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  • (PMID = 17717607.001).
  • [ISSN] 0001-527X
  • [Journal-full-title] Acta biochimica Polonica
  • [ISO-abbreviation] Acta Biochim. Pol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Isoflavones; 00BH33GNGH / Cadmium; 4TI98Z838E / Estradiol; 6287WC5J2L / daidzein; SY7Q814VUP / Calcium
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2. Kamel H, Abdelazim I, Habib SM, El Shourbagy MAA, Ahmed NS: Immunoexpression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours. J Obstet Gynaecol Can; 2010 Jun;32(6):580-586
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  • [Title] Immunoexpression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours.
  • OBJECTIVES: This study was designed to evaluate the expression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours and to detect the relation between the degree of MMP-2 expression and the histological grade and surgical stage of the studied cases.
  • METHODS: This study was conducted in Ain Shams University Maternity Hospital in Cairo, Egypt, between March 2004 and December 2005.
  • Thirty patients with malignant ovarian epithelial tumours diagnosed after histopathological examination of the specimens were included in this study.
  • In this study, there was a direct correlation between the degree of expression of MMP-2 and histologically undifferentiated or advanced stages of ovarian epithelial tumours.
  • [MeSH-major] Matrix Metalloproteinase 2 / metabolism. Neoplasms, Glandular and Epithelial / enzymology. Ovarian Neoplasms / enzymology

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  • (PMID = 20569539.001).
  • [ISSN] 1701-2163
  • [Journal-full-title] Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
  • [ISO-abbreviation] J Obstet Gynaecol Can
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] EC 3.4.24.24 / Matrix Metalloproteinase 2
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3. Hanai M, Esashi T: The effects of calcium, phosphorus, magnesium, sodium, and zinc in improving the depression of gonadal development in growing male rats kept under a disturbed daily rhythm-investigations based on the L(16)(2(15))-type orthogonal array. J Nutr Sci Vitaminol (Tokyo); 2006 Oct;52(5):368-75
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  • Five minerals (calcium (Ca), phosphorus (P), magnesium (Mg), sodium (Na), and zinc (Zn)) were selected as experimental factors, and the dietary content of these minerals was normal (AIN-76 diet) or 1/3.5 of the normal content.
  • Among the N-groups, the highest value was observed under the low-Ca, normal-Mg, and low-Na diet.

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  • (PMID = 17190108.001).
  • [ISSN] 0301-4800
  • [Journal-full-title] Journal of nutritional science and vitaminology
  • [ISO-abbreviation] J. Nutr. Sci. Vitaminol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Calcium, Dietary; 0 / Phosphorus, Dietary; 0 / Sodium, Dietary; 3XMK78S47O / Testosterone; I38ZP9992A / Magnesium; J41CSQ7QDS / Zinc
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4. Grases F, Sanchis P, Perello J, Isern B, Prieto RM, Fernandez-Palomeque C, Fiol M, Bonnin O, Torres JJ: Phytate (Myo-inositol hexakisphosphate) inhibits cardiovascular calcifications in rats. Front Biosci; 2006;11:136-42
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  • Calcification is an undesirable disorder, which frequently occurs in the heart vessels.
  • All rats were fed AIN 76-A diet (a purified diet in which InsP6 is undetectable).

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  • (PMID = 16146720.001).
  • [ISSN] 1093-9946
  • [Journal-full-title] Frontiers in bioscience : a journal and virtual library
  • [ISO-abbreviation] Front. Biosci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 1406-16-2 / Vitamin D; 6M3C89ZY6R / Nicotine; 7IGF0S7R8I / Phytic Acid; RWP5GA015D / Potassium; SY7Q814VUP / Calcium
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5. Komura M, Kanamori Y, Sugiyama M, Tomonaga T, Suzuki K, Hashizume K, Goishi K: A female infant who had both complete VACTERL association and MURCS association: report of a case. Surg Today; 2007;37(10):878-80
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  • Esophageal atresia type A with long gap, anal atresia, cardiac anomaly (atrial septal defect and patent ductus arteriosus), thoracic vertebral dysplasia, left renal agenesis, and minor anomalies (left-side facial nerve palsy, left-side difficulty in hearing, and the absence of the right thenar) had been diagnosed by various examinations.
  • We recognized vaginal atresia during a radical operation for anal atresia (rectovestibular fistula) at 8 months of age.
  • MURCS association includes Mullerian duct aplasia or hypoplasia, renal aplasia, and cervicothoracic somite dysplasia.
  • [MeSH-major] Abnormalities, Multiple / diagnosis. Anus, Imperforate / diagnosis. Bone Diseases, Developmental / diagnosis. Vagina / abnormalities

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  • (PMID = 17879038.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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6. Barreda B F, Combe G J, Valdez P LA, Sánchez L J: [Clinical aspects in polyps of the colon]. Rev Gastroenterol Peru; 2007 Apr-Jun;27(2):131-47
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  • [Transliterated title] Aspectos clínicos de los pólipos colónicos.
  • OBJECTIVES: To evaluate the relation between the histologic type of the colon polyps, its location, the degree of dysplasia, the size, its possible commitment by carcinoma, the age, sex and the handling that has occurred them, in a series of 684 patients of the National Institute of Enfermedades Neoplásicas (INEN) between the 1 of January from 1974 to the 31 of March of the 2004.
  • MATERIAL AND METHODS: The revision of clinical histories of 840 patients with the diagnosis of colon polyp was made who attended the service of Gastroenterology of the INEN between the 1 of January from 1974 to the 31 of March of 2004 and a card predesigned for each clinical history filled.
  • 156 patients by diagnosis related to cancer and familiar adenomatouspoliposis did not include themselves.
  • Other endoscopic findings were: internal hemorrhoids (172), colonic diverticulosis (50), anal fissure (4), and nonspecific ulcerative colitis (2).
  • Adenocarcinoma (carcinomas on adenomas), was present mainly in polyps villous type, with dysplasia severe and greater to 10 mm.
  • Nevertheless, in smaller polyps of 5mm with dysplasia severe, was a polyp invaded by cancer, that represents the 0,8% of millimetric polyps.
  • The colectomy was necessary in 3% of all the made interventions, dysplasia severe or carcinoma was made in adenomatous polyps with, and in greater percentage in greater polyps of 20 mm (53%).
  • The carcinoma is more probable with severe dysplasia and greater size of the adenoma.
  • All polyps, from the millimetric ones, including the hyperplasic, must be considered marks of neoplasia and extirpated in its totality.

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  • (PMID = 17712391.001).
  • [ISSN] 1022-5129
  • [Journal-full-title] Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
  • [ISO-abbreviation] Rev Gastroenterol Peru
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Peru
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7. Carlson CB, Gunderson KA, Mosher DF: Mutations targeting intermodular interfaces or calcium binding destabilize the thrombospondin-2 signature domain. J Biol Chem; 2008 Oct 3;283(40):27089-99
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  • We explored the significance of these structural elements by examining the impact of 10 different mutations known to result in pseudoachondrodysplasia or multiple epiphyseal dysplasia when found in the homologous wire and lectin-like modules of thrombospondin-5 (THBS-5).

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  • (PMID = 18682400.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / HL07899; United States / NHLBI NIH HHS / HL / HL54462; United States / NCRR NIH HHS / RR / S10 RR13790
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Epitopes; 0 / Thrombospondins; 0 / thrombospondin 2; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ PMC2555992
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8. Mukhopadhyay S, Rajaratnam V, Mukherjee S, Das SK: Control of peripheral benzodiazepine receptor-mediated breast cancer in rats by soy protein. Mol Carcinog; 2008 Apr;47(4):310-9
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  • Breast tumors were induced by gavage administration of a single dose (80 mg/kg) of dimethylbenz[a]anthracene (DMBA) into 50-d old female Sprague Dawley rats, maintained on a standard AIN-76A diet containing either casein or soy protein.

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17932947.001).
  • [ISSN] 1098-2744
  • [Journal-full-title] Molecular carcinogenesis
  • [ISO-abbreviation] Mol. Carcinog.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / G12RR03032; United States / NCI NIH HHS / CA / U54CA91408; United States / NINDS NIH HHS / NS / U54NS041071; United States / NCRR NIH HHS / RR / U54RR019192
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzodiazepinones; 0 / Carcinogens; 0 / Ligands; 0 / Receptors, GABA-A; 0 / Soybean Proteins; 10028-17-8 / Tritium; 14439-61-3 / 4'-chlorodiazepam; 57-97-6 / 9,10-Dimethyl-1,2-benzanthracene
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9. Siqueira EM, Arruda SF, de Vargas RM, de Souza EM: Beta-carotene from cassava (Manihot esculenta Crantz) leaves improves vitamin A status in rats. Comp Biochem Physiol C Toxicol Pharmacol; 2007 Jul-Aug;146(1-2):235-40
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  • Rats were separated into three groups and fed with a modified AIN-93G--vitamin A deficient--diet.

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  • (PMID = 17261381.001).
  • [ISSN] 1532-0456
  • [Journal-full-title] Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
  • [ISO-abbreviation] Comp. Biochem. Physiol. C Toxicol. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Plant Extracts; 01YAE03M7J / beta Carotene; 11103-57-4 / Vitamin A
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10. Dawodu A, Al-Gazali L, Varady E, Varghese M, Nath K, Rajan V: Genetic contribution to high neonatally lethal malformation rate in the United Arab Emirates. Community Genet; 2005;8(1):31-4
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  • OBJECTIVES: We examined the contribution of genetic disorders to congenital anomalies (CA) causing neonatal deaths in the Al Ain Medical District (AMD) in the United Arab Emirates (UAE) because of the high consanguineous marriage rate in the community.

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 15767752.001).
  • [ISSN] 1422-2795
  • [Journal-full-title] Community genetics
  • [ISO-abbreviation] Community Genet
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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11. Skerlev M, Ljubojevic S: [The specifities of the HPV-genital infections in males]. Med Glas (Zenica); 2010 Aug;7(2):89-95
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  • Anogenital warts (condylomata acuminata) are the most common lesions presented in men, however, during the last decade the other HPV-associated exaggerated lesions such as condylomata plana, penile, scrotal, and anal intraepithelial neoplasias, as well as the penile, urine bladder and prostate cancer have been studied somewhat more extensively.
  • Bowen, different kinds of eryhtroplasia both in men and women and a large spectrum of HPV-induced dermatovenereological entities in genital region including high-grade intraepithelial genital neoplasias, such as penile, anal, scrotal, vulvar, vaginal etc. (thus not only cervical), and, last but not least - the anogenital warts.

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  • (PMID = 21258302.001).
  • [ISSN] 1840-0132
  • [Journal-full-title] Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina
  • [ISO-abbreviation] Med Glas (Zenica)
  • [Language] hrv
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bosnia and Herzegovina
  • [Chemical-registry-number] 0 / Papillomavirus Vaccines
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12. Nagarajan S, Stewart BW, Badger TM: Soy isoflavones attenuate human monocyte adhesion to endothelial cell-specific CD54 by inhibiting monocyte CD11a. J Nutr; 2006 Sep;136(9):2384-90
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  • Female Sprague-Dawley rats were fed AIN-93G diets containing soy protein isolate or casein.

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  • (PMID = 16920859.001).
  • [ISSN] 0022-3166
  • [Journal-full-title] The Journal of nutrition
  • [ISO-abbreviation] J. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, CD11a; 0 / Caseins; 0 / Interleukin-6; 0 / Interleukin-8; 0 / Isoflavones; 0 / Lipoproteins, LDL; 0 / Soybean Proteins; 0 / oxidized low density lipoprotein; 126547-89-5 / Intercellular Adhesion Molecule-1
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13. Tamagawa K, Nakayama-Imaohji H, Wakimoto S, Ichimura M, Kuwahara T: Utilization of titanium oxide-like compound as an inorganic phosphate adsorbent for the control of serum phosphate level in chronic renal failure. J Med Invest; 2010 Aug;57(3-4):275-83
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  • To evaluate the phosphate binding potential of TAP in vivo, adenine-induced CRF rats were fed AIN-76 diet containing 3% TAP, 10% TAP, 3% sevelamer hydrochloride (clinical phosphate adsorbent), or 3% calcium carbonate, and serum levels of phosphate and calcium and urinary phosphate were compared with those in untreated CRF rats.

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  • (PMID = 20847528.001).
  • [ISSN] 1349-6867
  • [Journal-full-title] The journal of medical investigation : JMI
  • [ISO-abbreviation] J. Med. Invest.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Phosphates; 15FIX9V2JP / titanium dioxide; D1JT611TNE / Titanium
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14. Sukemori S, Kurosawa A, Ikeda S, Kurihara Y: Investigation on the growth of coprophagy-prevented rats with supplemented vitamin B12. J Anim Physiol Anim Nutr (Berl); 2006 Oct;90(9-10):402-6
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  • In the second experiment, coprophagy-prevented rats were fed AIN-93G at the recommended vitamin B12 level (25 microg/kg diet), at 100 times the level and at 1000 times the level respectively.

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  • (PMID = 16958797.001).
  • [ISSN] 0931-2439
  • [Journal-full-title] Journal of animal physiology and animal nutrition
  • [ISO-abbreviation] J Anim Physiol Anim Nutr (Berl)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] P6YC3EG204 / Vitamin B 12
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15. Al-Kaabi J, Al-Maskari F, Saadi H, Afandi B, Parkar H, Nagelkerke N: Physical activity and reported barriers to activity among type 2 diabetic patients in the United arab emirates. Rev Diabet Stud; 2009;6(4):271-8
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  • METHODS: This is a cross-sectional study of type 2 diabetic patients who participated in the outpatient clinics in Al-Ain District, during 2006.
  • RESULTS: Of the 390 patients recruited, only 25% reported an increase in their physical activity levels following the diagnosis of diabetes, and only 3% reported physical activity levels that meet the recommended guidelines.

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  • (PMID = 20043039.001).
  • [ISSN] 1614-0575
  • [Journal-full-title] The review of diabetic studies : RDS
  • [ISO-abbreviation] Rev Diabet Stud
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2836198
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16. Adam SH, Eid HO, Barss P, Lunsjo K, Grivna M, Torab FC, Abu-Zidan FM: Epidemiology of geriatric trauma in United Arab Emirates. Arch Gerontol Geriatr; 2008 Nov-Dec;47(3):377-82
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  • The data of Al-Ain Hospital Trauma Registry were prospectively collected over a period of 3 years (2003-2006).
  • [MeSH-major] Cause of Death. Hospital Mortality / trends. Wounds and Injuries / diagnosis. Wounds and Injuries / epidemiology

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  • (PMID = 17936381.001).
  • [ISSN] 1872-6976
  • [Journal-full-title] Archives of gerontology and geriatrics
  • [ISO-abbreviation] Arch Gerontol Geriatr
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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17. Xiao R, Carter JA, Linz AL, Ferguson M, Badger TM, Simmen FA: Dietary whey protein lowers serum C-peptide concentration and duodenal SREBP-1c mRNA abundance, and reduces occurrence of duodenal tumors and colon aberrant crypt foci in azoxymethane-treated male rats. J Nutr Biochem; 2006 Sep;17(9):626-34
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  • Pregnant Sprague-Dawley rats and their progeny were fed AIN-93G diets containing casein (CAS, control diet) or WPH as the sole protein source.

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  • (PMID = 16504496.001).
  • [ISSN] 0955-2863
  • [Journal-full-title] The Journal of nutritional biochemistry
  • [ISO-abbreviation] J. Nutr. Biochem.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CB / N02-CB-07008
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / C-Peptide; 0 / Dietary Proteins; 0 / Milk Proteins; 0 / Sterol Regulatory Element Binding Protein 1; 0 / Whey Proteins; MO0N1J0SEN / Azoxymethane
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18. Delgado-Andrade C, Seiquer I, Navarro MP: Comparative effects of glucose-lysine versus glucose-methionine Maillard reaction products consumption: in vitro and in vivo calcium availability. Mol Nutr Food Res; 2005 Jul;49(7):679-84
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  • For 21 days, the rats were fed the AIN-93G diet (control group) or diets containing separately 3% of the heated mixtures (GL30, GL90, GM30, and GM90 groups, respectively).

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  • (PMID = 15786517.001).
  • [ISSN] 1613-4125
  • [Journal-full-title] Molecular nutrition & food research
  • [ISO-abbreviation] Mol Nutr Food Res
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] AE28F7PNPL / Methionine; IY9XDZ35W2 / Glucose; K3Z4F929H6 / Lysine; SY7Q814VUP / Calcium
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19. Scheurer ME, Guillaud M, Tortolero-Luna G, Follen M, Adler-Storthz K: Epidemiologic modeling of cervical dysplasia with molecular and cytopathological markers. Gynecol Oncol; 2007 Oct;107(1 Suppl 1):S163-9
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  • [Title] Epidemiologic modeling of cervical dysplasia with molecular and cytopathological markers.
  • OBJECTIVES: Conventional cervical screening is insufficient at identifying patients who are likely to progress from cervical dysplasia to carcinoma.

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  • (PMID = 17727928.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA057730-13; United States / NCI NIH HHS / CA / P01 CA082710; United States / NCI NIH HHS / CA / R25 CA057730; United States / NCI NIH HHS / CA / R25 CA057730-16; United States / NCI NIH HHS / CA / CA057730-15; United States / NCI NIH HHS / CA / CA057730-14; United States / NCI NIH HHS / CA / R25 CA057730-12; None / None / / R25 CA057730-16; United States / NCI NIH HHS / CA / P01 CA082710-04; United States / NCI NIH HHS / CA / P01 CA082710-08; United States / NCI NIH HHS / CA / CA057730-12; United States / NCI NIH HHS / CA / P01 CA082710-07; United States / NCI NIH HHS / CA / P01CA82710; United States / NCI NIH HHS / CA / CA082710-08; United States / NCI NIH HHS / CA / P01 CA082710-06; United States / NCI NIH HHS / CA / CA082710-07; United States / NCI NIH HHS / CA / R25 CA057730-15; United States / NCI NIH HHS / CA / CA082710-05; United States / NCI NIH HHS / CA / P01 CA082710-05; United States / NCI NIH HHS / CA / R25CA57730; United States / NCI NIH HHS / CA / R25 CA057730-13; United States / NCI NIH HHS / CA / CA082710-04; United States / NCI NIH HHS / CA / CA082710-06; United States / NCI NIH HHS / CA / R25 CA057730-14
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral; 0 / RNA, Messenger
  • [Other-IDs] NLM/ NIHMS32449; NLM/ PMC2978043
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20. Ralston NV, Blackwell JL 3rd, Raymond LJ: Importance of molar ratios in selenium-dependent protection against methylmercury toxicity. Biol Trace Elem Res; 2007 Dec;119(3):255-68
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  • Rats were fed AIN-93G-based low-Se torula yeast diets or diets augmented with sodium selenite to attain adequate- or rich-Se levels (0.1, 1.0 or 15 micromol/kg, respectively) These diets were prepared with no added methylmercury (MeHg) or with moderate- or high-MeHg (0.2, 10 or 60 micromol/kg, respectively).

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  • (PMID = 17916948.001).
  • [ISSN] 0163-4984
  • [Journal-full-title] Biological trace element research
  • [ISO-abbreviation] Biol Trace Elem Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Methylmercury Compounds; FXS1BY2PGL / Mercury; H6241UJ22B / Selenium
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21. Dunn AJ, Salonen DC, Anastakis DJ: MR imaging findings of anterior interosseous nerve lesions. Skeletal Radiol; 2007 Dec;36(12):1155-62
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  • OBJECTIVE: To study and characterise the MR imaging findings of lesions of the anterior interosseous nerve (AIN).
  • MATERIALS AND METHODS: Magnetic resonance imaging (MRI) findings of the forearm of ten patients referred to our institution with suspected AIN lesions were retrospectively studied.
  • Two musculoskeletal radiologists assessed the forearm musculature for oedema in the distribution of the AIN, median, posterior interosseous and radial nerves on T2-weighted (T2W) fat-saturated sequences.
  • RESULTS: Six patients had undergone surgical exploration; five of these had surgically confirmed AIN compression.
  • Four patients had diagnoses other than AIN compression made on imaging features.
  • Of the cases of proven AIN compression, oedema within the pronator quadratus (PQ) muscle was identified in all cases.
  • The four cases of non-AIN compression demonstrated muscle oedema patterns that were atypical for the AIN distribution.
  • CONCLUSIONS: MRI is a useful investigation in the diagnostic workup of AIN syndrome.
  • AIN syndrome is likely when there is diffuse oedema of AIN innervated muscles on T2W fat-saturated images.
  • The most reliable sign of an AIN lesion is oedema within the PQ.
  • Oedema in the flexor carpi radialis, FDP3 and FDP4, although not in the classical distribution of the AIN, does not preclude the diagnosis of AIN syndrome.
  • [MeSH-major] Forearm / innervation. Magnetic Resonance Imaging / methods. Nerve Compression Syndromes / diagnosis. Neuritis / diagnosis

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  • (PMID = 17938918.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
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22. Ling PR, Bistrian BR: Comparison of the effects of food versus protein restriction on selected nutritional and inflammatory markers in rats. Metabolism; 2009 Jun;58(6):835-42
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  • We previously demonstrated that feeding a 2% protein AIN-76 diet ad libitum for 14 days resulted in substantial clinical and biochemical changes including weight loss, hypoglycemia, hypoalbuminemia, higher levels of plasma cytokines, oxidative stress in the liver, and activation of inflammatory signaling to interleukin (IL)-6, as compared with a 20% protein diet.
  • Because these latter 3 markers were not examined previously, 20 rats were fed an AIN-76 diet, either with 20% or 2% protein, ad libitum for 14 days.

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  • (PMID = 19375129.001).
  • [ISSN] 1532-8600
  • [Journal-full-title] Metabolism: clinical and experimental
  • [ISO-abbreviation] Metab. Clin. Exp.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / P30 DK040561; None / None / / P30 DK040561-11; United States / NIDDK NIH HHS / DK / P30 DK040561-11
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Fatty Acids, Nonesterified; 0 / Ghrelin; W980KJ009P / Corticosterone
  • [Other-IDs] NLM/ NIHMS330216; NLM/ PMC3201784
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23. Wang J, Eltoum IE, Lamartiniere CA: Genistein chemoprevention of prostate cancer in TRAMP mice. J Carcinog; 2007 Mar 16;6:3
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  • The treatments were 250 mg genistein/kg AIN-76A diet 1) prepubertally only, 2) in adulthood only or 3) through out life.
  • Controls received AIN-76A diet.
  • By 28 weeks of age, 100% TRAMP mice fed control diet developed prostatic intraepithelial neoplasia (PIN) or adenocarcinomas with 6%, 16%, 44% and 34% developing high grade PIN, well differentiated, moderately differentiated and poorly differentiated prostatic adenocarcinomas, respectively.

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  • (PMID = 17367528.001).
  • [ISSN] 1477-3163
  • [Journal-full-title] Journal of carcinogenesis
  • [ISO-abbreviation] J Carcinog
  • [Language] ENG
  • [Grant] United States / NIEHS NIH HHS / ES / R01 ES011743
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC1832183
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24. Esteve JB, Launay-Vacher V, Brocheriou I, Grimaldi A, Izzedine H: COX-2 inhibitors and acute interstitial nephritis: case report and review of the literature. Clin Nephrol; 2005 May;63(5):385-9
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  • We report a case of biopsy-proven acute interstitial nephritis (AIN) in a 50-year-old diabetic woman, who had been treated with celecoxib for 4 weeks before presentation.
  • A kidney biopsy specimen showed AIN with intense tubuli and eosinophilic infiltrate in the interstitium.
  • A review of the literature yielded eight cases of COX-2 inhibitor-associated AIN with a biopsy-proven diagnosis.
  • Among the reported cases, AIN was diagnosed after an average of 8.3 months of therapy (SD 12 months, range 3 days - 3 years) with 25 mg rofecoxib or 200 mg celecoxib daily.
  • Renal failure was common at the time of diagnosis.
  • Mean serum creatinine levels were 0.86 +/- 0.11 mg/dl, 5.66 +/- 3.50 mg/dl and 1.15 +/- 0.24 before treatment, at time of diagnosis and 1 - 2 months after COX-2 inhibitor withdrawal, respectively.

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  • (PMID = 15909599.001).
  • [ISSN] 0301-0430
  • [Journal-full-title] Clinical nephrology
  • [ISO-abbreviation] Clin. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Cyclooxygenase Inhibitors; 9PHQ9Y1OLM / Prednisolone
  • [Number-of-references] 25
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25. Dungarwalla M, Marsh JC, Tooze JA, Lucas G, Ouwehand W, Pettengell R, Dearden CE, Gordon Smith EC, Elebute MO: Lack of clinical efficacy of rituximab in the treatment of autoimmune neutropenia and pure red cell aplasia: implications for their pathophysiology. Ann Hematol; 2007 Mar;86(3):191-7
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  • Six patients had autoimmune neutropenia (AIN), two had pure red cell aplasia (PRCA), one had AIN and autoimmune haemolytic anaemia, one had AIN and immune thrombocytopaenia purpura (ITP) and one had PRCA and ITP.
  • Six of eight patients with AIN and all three patients with PRCA did not respond.
  • Two patients died: one with resistant AIN and autoimmune haemolytic anaemia died of pneumocytis pneumonia infection, and one with PRCA and ITP died of an acute exacerbation of bronchiectasis.
  • Rituximab in AIN and PRCA appears to be less effective than Campath-1H when compared to historical data from our group.
  • This supports the hypothesis that T cells may be important in the pathophysiology of AIN and PRCA.

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  • (PMID = 17123083.001).
  • [ISSN] 1432-0584
  • [Journal-full-title] Annals of hematology
  • [ISO-abbreviation] Ann. Hematol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Immunologic Factors; 4F4X42SYQ6 / Rituximab
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26. Oon SF, Hanly A, Winter DC: Pap smears for men: a vision of the future? Ir J Med Sci; 2010 Sep;179(3):459-62
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  • BACKGROUND: Anal intraepithelial neoplasia (AIN) rarely receives as much publicity as its neighbouring orifice, the cervix.
  • As in the cervix, intraepithelial neoplasias are precursors to cancer in the anal canal.
  • AIN and cervical interstitial neoplasia (CIN) undergo dysplasia as a consequence of human papillomavirus (HPV) infection.
  • Anal cancer, however, has been rising, with a predilection for human immunodeficiency virus-infected men.
  • HPV causes a squamous epithelial dysplasia and converts healthy tissue into AINs of increasing severity until anal cancer manifests.
  • CONCLUSIONS: The paper concludes by briefly discussing the implications of a national screening programme against AIN in the future.
  • [MeSH-major] Anus Neoplasms / virology. Carcinoma in Situ / virology
  • [MeSH-minor] Adult. Anus Diseases / surgery. Anus Diseases / therapy. Anus Diseases / virology. Cervical Intraepithelial Neoplasia / virology. Condylomata Acuminata / surgery. Condylomata Acuminata / therapy. Condylomata Acuminata / virology. Cytodiagnosis. Female. Humans. Male. Papillomavirus Infections. Recurrence. Uterine Cervical Neoplasms / virology

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  • [CommentIn] Ir J Med Sci. 2010 Jun;179(2):319 [19921312.001]
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  • (PMID = 19763675.001).
  • [ISSN] 1863-4362
  • [Journal-full-title] Irish journal of medical science
  • [ISO-abbreviation] Ir J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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27. Fox PA, Seet JE, Stebbing J, Francis N, Barton SE, Strauss S, Allen-Mersh TG, Gazzard BG, Bower M: The value of anal cytology and human papillomavirus typing in the detection of anal intraepithelial neoplasia: a review of cases from an anoscopy clinic. Sex Transm Infect; 2005 Apr;81(2):142-6
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  • [Title] The value of anal cytology and human papillomavirus typing in the detection of anal intraepithelial neoplasia: a review of cases from an anoscopy clinic.
  • BACKGROUND: Previous studies have reached differing conclusions about the utility of anal cytology as a screening tool for anal intraepithelial neoplasia (AIN).
  • Comparison was made between results of anal cytology using the sampling method of Palefsky, and histological findings of biopsies taken from abnormal areas seen on high resolution anoscopic examination of the anal canal.
  • At screening of 34 asymptomatic men, 83% had anal cytological dysplasia and 78% had AIN.
  • CONCLUSION: Anal cytology by the Palefsky method is simple to undertake, has a sensitivity and specificity comparable with cervical cytology, and can therefore be used as the basis of a pilot screening project in centres with large cohorts of HIV positive homosexual men who have a high risk of developing anal carcinoma.
  • [MeSH-major] Anus Neoplasms / pathology. Bisexuality. Carcinoma in Situ / pathology. Homosexuality, Male. Papillomavirus Infections / pathology

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  • (PMID = 15800092.001).
  • [ISSN] 1368-4973
  • [Journal-full-title] Sexually transmitted infections
  • [ISO-abbreviation] Sex Transm Infect
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1764665
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28. Santoso JT, Long M, Crigger M, Wan JY, Haefner HK: Anal intraepithelial neoplasia in women with genital intraepithelial neoplasia. Obstet Gynecol; 2010 Sep;116(3):578-82
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  • [Title] Anal intraepithelial neoplasia in women with genital intraepithelial neoplasia.
  • OBJECTIVE: To estimate the prevalence of anal intraepithelial neoplasia in heterosexual women with genital intraepithelial neoplasia, and to compare anal cytology with colposcopy for their effectiveness in anal intraepithelial neoplasia screening.
  • METHODS: Women with confirmed intraepithelial neoplasia on the cervix, vagina, or vulva were referred for gynecologic oncology care.
  • All patients underwent anal cytology and high-resolution anoscopy.
  • RESULTS: Women with average age of 39.6 years (range 14 to 83 years) underwent anal cytology and anoscopy (N=205).
  • Of the 205 patients with genital intraepithelial neoplasia, 25 patients (12.2%) had biopsy-proven anal intraepithelial neoplasia.
  • Twelve patients (5.9%) had abnormal anal cytology (nine with atypical squamous cells of undetermined significance [ASC-US], three with low-grade squamous intraepithelial lesions [LSIL]).
  • None of the nine patients with anal ASC-US had biopsy-proven anal intraepithelial neoplasia.
  • Of the three patients with anal LSIL, two had anal intraepithelial neoplasia II and one had condyloma on biopsy.
  • However, 78 patients (38%) had abnormal anoscopy findings that resulted in 25 biopsy-proven anal intraepithelial neoplasias (8 anal intraepithelial neoplasia I, 5 anal intraepithelial neoplasia II, 12 anal intraepithelial neoplasia III)), condylomas (n=11), and hyperkeratosis (n=8).
  • Anoscopy identified 32% (25 patients) with anal intraepithelial neoplasia out of 78 abnormal anoscopic examinations.
  • In diagnosing anal intraepithelial neoplasia, anoscopy has 100% sensitivity and 71% specificity; anal cytology has 8% sensitivity and 94% specificity.
  • CONCLUSION: Patients with cervical, vulvar, and vaginal intraepithelial neoplasia have 12.2% prevalence of anal intraepithelial neoplasia and should be screened with high-resolution anoscopy.
  • In anal intraepithelial neoplasia screening, anoscopy is more sensitive but less specific than anal cytology.
  • [MeSH-major] Anus Neoplasms / epidemiology. Carcinoma in Situ / epidemiology. Genital Neoplasms, Female / epidemiology

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  • [CommentIn] Obstet Gynecol. 2010 Sep;116(3):566-7 [20733435.001]
  • [ErratumIn] Obstet Gynecol. 2010 Nov;116(5):1224
  • (PMID = 20733438.001).
  • [ISSN] 1873-233X
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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29. Godlewski MM, Slazak P, Zabielski R, Piastowska A, Gralak MA: Quantitative study of soybean-induced changes in proliferation and programmed cell death in the intestinal mucosa of young rats. J Physiol Pharmacol; 2006 Nov;57 Suppl 7:125-33
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  • The use of soybean in human and animal nutrition is limited because of high content of bioactive compounds: enzyme inhibitors, polyphenols, goitrogens, phytates, saponins, sugars, and agglutinins.
  • The experiment was performed on 30 Wistar rats fed AIN-93 based diets.

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  • (PMID = 17228100.001).
  • [ISSN] 1899-1505
  • [Journal-full-title] Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
  • [ISO-abbreviation] J. Physiol. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Poland
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30. Mahid SS, Colliver DW, Crawford NP, Martini BD, Doll MA, Hein DW, Cobbs GA, Petras RE, Galandiuk S: Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma. BMC Med Genet; 2007 May 30;8:28
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  • [Title] Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma.
  • METHODS: A case control study was performed with 729 Caucasian participants, 123 CRC, 201 CD, 167 UC, 15 IBD dysplasia/cancer and 223 controls.

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  • (PMID = 17537267.001).
  • [ISSN] 1471-2350
  • [Journal-full-title] BMC medical genetics
  • [ISO-abbreviation] BMC Med. Genet.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA034627-21; United States / NCI NIH HHS / CA / R01 CA034627; United States / NCI NIH HHS / CA / R01 CA034627-21; United States / NCI NIH HHS / CA / R01-CA34627
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Isoenzymes; EC 2.3.1.5 / Arylamine N-Acetyltransferase; EC 2.3.1.5 / N-acetyltransferase 1
  • [Other-IDs] NLM/ PMC1903350
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31. Tulchinsky H, Dotan I, Alper A, Brazowski E, Klausner JM, Halpern Z, Rabau M: Comprehensive pouch clinic concept for follow-up of patients after ileal pouch anal anastomosis: report of 3 years' experience in a tertiary referral center. Inflamm Bowel Dis; 2008 Aug;14(8):1125-32
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  • [Title] Comprehensive pouch clinic concept for follow-up of patients after ileal pouch anal anastomosis: report of 3 years' experience in a tertiary referral center.
  • The risk factors for the development of pouchitis were time since surgery, >1-stage surgery, and reason for surgery (acute exacerbation/intractable disease more than dysplasia/cancer); the latter was the only independent risk factor.

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  • (PMID = 18338779.001).
  • [ISSN] 1536-4844
  • [Journal-full-title] Inflammatory bowel diseases
  • [ISO-abbreviation] Inflamm. Bowel Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Harper CE, Patel BB, Wang J, Arabshahi A, Eltoum IA, Lamartiniere CA: Resveratrol suppresses prostate cancer progression in transgenic mice. Carcinogenesis; 2007 Sep;28(9):1946-53
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  • In the current study, Transgenic Adenocarcinoma Mouse Prostate males were fed resveratrol (625 mg resveratrol per kg AIN-76A diet) or phytoestrogen-free, control diet (AIN-76A) starting at 5 weeks of age.

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  • (PMID = 17675339.001).
  • [ISSN] 0143-3334
  • [Journal-full-title] Carcinogenesis
  • [ISO-abbreviation] Carcinogenesis
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 47888; United States / NCI NIH HHS / CA / P30 CA-13148-34
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Stilbenes; Q369O8926L / resveratrol
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33. Deshong D, Henderson A: The trainee assistant in nursing: a pilot exercise in building and retaining a workforce. Aust Health Rev; 2010 Mar;34(1):41-3
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  • The program - which has included education sessions with registered nurses about the role of the AIN, delegation and supervision, and has also sustained support to the participants throughout the duration of their employment - has delivered benefits locally to the Princess Alexandra Hospital (PAH) and, broadly, to the nursing profession.

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  • (PMID = 20334755.001).
  • [ISSN] 0156-5788
  • [Journal-full-title] Australian health review : a publication of the Australian Hospital Association
  • [ISO-abbreviation] Aust Health Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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34. Bhakta KY, Jiang W, Couroucli XI, Fazili IS, Muthiah K, Moorthy B: Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury. Toxicol Appl Pharmacol; 2008 Dec 1;233(2):169-78
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  • Supplemental oxygen, used to treat pulmonary insufficiency in newborns, contributes to the development of bronchopulmonary dysplasia (BPD).

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  • [Cites] Am J Physiol. 1999 Dec;277(6 Pt 1):L1214-23 [10600893.001]
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  • (PMID = 18824009.001).
  • [ISSN] 1096-0333
  • [Journal-full-title] Toxicology and applied pharmacology
  • [ISO-abbreviation] Toxicol. Appl. Pharmacol.
  • [Language] ENG
  • [Grant] United States / NIEHS NIH HHS / ES / R01ES 009132; United States / NHLBI NIH HHS / HL / R01HL 087174; United States / NHLBI NIH HHS / HL / F32 HL082431-02; United States / NIEHS NIH HHS / ES / R01 ES009132; United States / NHLBI NIH HHS / HL / HL070921-02; United States / NHLBI NIH HHS / HL / HL087174-01A1; United States / NHLBI NIH HHS / HL / HL082431-01; United States / NHLBI NIH HHS / HL / F32 HL082431-01; United States / NIEHS NIH HHS / ES / R01 ES009132-08; United States / NHLBI NIH HHS / HL / R01HL 070921; United States / NHLBI NIH HHS / HL / F32 HL082431; United States / NIEHS NIH HHS / ES / ES009132-06A2; United States / NHLBI NIH HHS / HL / R01 HL087174; United States / NHLBI NIH HHS / HL / HL082431-02; United States / NHLBI NIH HHS / HL / R01 HL070921-03; United States / NHLBI NIH HHS / HL / HL070921-01A2; United States / NHLBI NIH HHS / HL / HL070921-03; United States / NIEHS NIH HHS / ES / R01 ES009132-06A2; United States / NIEHS NIH HHS / ES / ES009132-07; United States / NHLBI NIH HHS / HL / R01 HL087174-01A1; United States / NHLBI NIH HHS / HL / R01 HL070921-01A2; United States / NIEHS NIH HHS / ES / R01 ES009132-07; United States / NHLBI NIH HHS / HL / R01 HL070921-02; United States / NHLBI NIH HHS / HL / R01 HL070921; United States / NIEHS NIH HHS / ES / ES009132-08
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Apoproteins; 0 / RNA, Messenger; 0 / RNA, Small Interfering; 0 / Receptors, Aryl Hydrocarbon; EC 1.13.12.- / Luciferases; EC 1.14.14.1 / Cytochrome P-450 CYP1A1
  • [Other-IDs] NLM/ NIHMS84170; NLM/ PMC2646384
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35. Faguer S, Pillet A, Chassaing N, Merhenberger M, Bernadet-Monrozies P, Guitard J, Chauveau D: Nephropathy in Townes-Brocks syndrome (SALL1 mutation): imaging and pathological findings in adulthood. Nephrol Dial Transplant; 2009 Apr;24(4):1341-5
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  • The phenotype encompasses malformations of limbs (triphalangeal thumbs and pre-axial polydactyly), intestine (anal stenosis) and ears (dysplastic ear with perception hearing loss).
  • Renal involvement (hypo-dysplasia, multicystic kidneys or unilateral absence) is observed in almost half of patients and may progress to end-stage renal failure in childhood.
  • [MeSH-major] Kidney Failure, Chronic / diagnosis. Kidney Failure, Chronic / genetics. Transcription Factors / genetics

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  • (PMID = 19204018.001).
  • [ISSN] 1460-2385
  • [Journal-full-title] Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • [ISO-abbreviation] Nephrol. Dial. Transplant.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / SALL1 protein, human; 0 / Transcription Factors
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36. Lichtenstein GR, Cohen R, Yamashita B, Diamond RH: Quality of life after proctocolectomy with ileoanal anastomosis for patients with ulcerative colitis. J Clin Gastroenterol; 2006 Sep;40(8):669-77
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  • Less common reasons are dysplasia or cancer.
  • Consequently, surgery with total proctocolectomy and creation of an ileal J-pouch-anal anastomosis has become the procedure of choice for many patients without other therapeutic options.
  • Health-related quality of life (QOL) in patients with severe ulcerative colitis is so poor that, after ileal J-pouch-anal anastomosis, QOL is considered to improve in most clinical studies (8 studies, improved QOL; 1 study, no change; 1 study, QOL worse than general population).
  • However, QOL and bowel function after such surgery cannot be considered "normal" in all patients, because a substantial number still have problems with urgency, leakage, nocturnal soiling, sexual dysfunction, and pouchitis, and some require conversion to a permanent ileostomy after ileal J-pouch-anal anastomosis failure.
  • Thus, despite the availability of ileal J-pouch-anal anastomosis, surgery does not always restore all aspects of QOL to normal.
  • [MeSH-major] Anal Canal / surgery. Anastomosis, Surgical / adverse effects. Colitis, Ulcerative / surgery. Ileum / surgery. Proctocolectomy, Restorative / adverse effects. Quality of Life

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  • (PMID = 16940876.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 95
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37. Park JY, Pandher DS, Chun JY, Md ST: Antegrade humeral nailing through the rotator cuff interval: a new entry portal. J Orthop Trauma; 2008 Jul;22(6):419-25
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  • The conventional approach for antegrade intramedullary nailing (AIN) of humerus fractures is associated with persistent pain and compromised shoulder function.
  • Damage to the critical hypovascular zone of the rotator cuff near its insertion on the humerus and/or irritation of the subacromial space by prominent hardware are the factors believed to be responsible for poor shoulder function after AIN of the humerus.
  • The overall satisfaction rate was more than 90%, according to the ASES (American Shoulder and Elbow Society) score.

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  • (PMID = 18594308.001).
  • [ISSN] 1531-2291
  • [Journal-full-title] Journal of orthopaedic trauma
  • [ISO-abbreviation] J Orthop Trauma
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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38. Lessa NM, Nakajima VM, Matta SL, Peluzio MC, Sabarense CM, Costa NM: Deposition of trans fatty acid from industrial sources and its effect on different growth phases in rats. Ann Nutr Metab; 2010;57(1):23-34
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  • In this study, female Wistar rats were assigned to control diet (AIN-93G) or Trans diet groups (5% IP-TFA) after gestation.

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  • [Copyright] 2010 S. Karger AG, Basel.
  • (PMID = 20664255.001).
  • [ISSN] 1421-9697
  • [Journal-full-title] Annals of nutrition & metabolism
  • [ISO-abbreviation] Ann. Nutr. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Dietary Fats; 0 / Insulin; 0 / Trans Fatty Acids
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39. Wu K, Han T, Shen K, Li B, Peng T, Pan Y, Sun H, Liu C: Growth of vertically aligned InGaN nanorod arrays on p-type Si substrates for heterojunction diodes. J Nanosci Nanotechnol; 2010 Dec;10(12):8139-44
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  • InGaN nanorod arrays have been grown by molecular beam epitaxy on bare and high-temperature AIN-buffered Si(111) substrates.
  • It has been found that well vertically aligned InGaN nanorod arrays can be grown by using the high-temperature AIN buffer layer.
  • By using the high-temperature AIN buffer layer, the interface quality was improved, and uniform InGaN nanorods could be grown.

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  • (PMID = 21121307.001).
  • [ISSN] 1533-4880
  • [Journal-full-title] Journal of nanoscience and nanotechnology
  • [ISO-abbreviation] J Nanosci Nanotechnol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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40. Shpitz B, Giladi N, Sagiv E, Lev-Ari S, Liberman E, Kazanov D, Arber N: Celecoxib and curcumin additively inhibit the growth of colorectal cancer in a rat model. Digestion; 2006;74(3-4):140-4
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  • METHODS: Male rats were injected with DMH and randomly divided into four groups that consumed one of the following diets: (a) AIN-076 control diet;.
  • (b) AIN-076/curcumin (0.6%);.
  • (c) AIN-076/celecoxib (0.16%), or (d) AIN-076/celecoxib (0.16%) and curcumin (0.6%).

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  • Hazardous Substances Data Bank. CELECOXIB .
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  • [Copyright] 2006 S. Karger AG, Basel
  • (PMID = 17228149.001).
  • [ISSN] 1421-9867
  • [Journal-full-title] Digestion
  • [ISO-abbreviation] Digestion
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Pyrazoles; 0 / Sulfonamides; IT942ZTH98 / Curcumin; JCX84Q7J1L / Celecoxib
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41. Vogel LK, Saebø M, Skjelbred CF, Abell K, Pedersen ED, Vogel U, Kure EH: The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals. BMC Cancer; 2006 Jul 04;6:176
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  • METHODS: Using quantitative RT-PCR, we have determined the mRNA levels for matriptase and HAI-1 in colorectal cancer tissue (n = 9), severe dysplasia (n = 15), mild/moderate dysplasia (n = 21) and in normal tissue from the same individuals.
  • HAI-1 mRNA levels in both normal and affected tissue from individuals with severe dysplasia or carcinomas and in affected tissue with mild/moderate dysplasia were all significantly lower than mRNA levels observed in corresponding tissue from healthy control individuals.
  • HAI-1 mRNA levels were significantly lower in tissue displaying mild/moderate (p < 0.001) and severe (p < 0.01) dysplasia compared to normal tissue from the same patients.

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  • (PMID = 16820046.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Membrane Glycoproteins; 0 / Proteinase Inhibitory Proteins, Secretory; 0 / RNA, Messenger; 0 / SPINT1 protein, human; EC 3.4.21.- / Serine Endopeptidases; EC 3.4.21.109 / ST14 protein, human
  • [Other-IDs] NLM/ PMC1525198
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42. Bener A, Hyder AA, Schenk E: Trends in childhood injury mortality in a developing country: United Arab Emirates. Accid Emerg Nurs; 2007 Oct;15(4):228-33
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  • OBJECTIVE: To describe the epidemiology of a leading cause of childhood mortality in Al-Ain, United Arab Emirates (UAE)--injury.
  • SETTING: Al-Ain and Tawam Hospitals, and Preventive Medicine Department, Al-Ain, United Arab Emirates.
  • SUBJECTS: All cases that met the conditions established for the study: fell within the age group of 0 to 14 years, suffered from injuries, and were admitted to either Al-Ain or Tawam hospitals and subsequently died within the studied time period of 1 January 1995 to 31 December 2004.


43. Mokhtar GM, Matter RM, Shawki H, Abdel Aziz MM: Thrombin activatable fibrinolysis inhibitor (TAFI): relationship to hemostatic alteration in patients with beta-thalassemia. Pediatr Hematol Oncol; 2010 Aug;27(5):363-73
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  • Fifty-one thalassemic patients (mean age 10.79 +/- 5.59 years) (21 splenectomized thalassemia major patients, 18 nonsplenectomized thalassemia major patients, 12 nonsplenectomized thalassemia intermedia) were recruited from Pediatric Hematology Clinic, Ain Shams University; in addition, 32 healthy age- and sex-matched controls (10.31 +/- 5.58 years) were also included.

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  • (PMID = 20670166.001).
  • [ISSN] 1521-0669
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 9007-73-2 / Ferritins; EC 3.4.17.20 / Carboxypeptidase B2
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44. Palefsky JM: Human papillomavirus-related disease in men: not just a women's issue. J Adolesc Health; 2010 Apr;46(4 Suppl):S12-9
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  • HPV is associated with a variety of cancers in men, including anal cancer and a subset of penile and oral cancers.
  • The incidence of anal and oral cancers related to HPV is increasing in the general population and is growing even faster among individuals who are immunocompromised because of human immunodeficiency virus (HIV) infection.
  • Likewise, anal HPV infection and anal intraepithelial neoplasia are very common throughout a wide range of ages in both HIV-negative and HIV-positive men who have sex with men.

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  • [ErratumIn] J Adolesc Health. 2010 Jun;46(6):614
  • (PMID = 20307839.001).
  • [ISSN] 1879-1972
  • [Journal-full-title] The Journal of adolescent health : official publication of the Society for Adolescent Medicine
  • [ISO-abbreviation] J Adolesc Health
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA054053-10; United States / NCI NIH HHS / CA / R01 CA054053; United States / NCI NIH HHS / CA / CA088739-05; United States / NCI NIH HHS / CA / R01 CA088739; United States / NCI NIH HHS / CA / R01 CA088739-05; United States / NCI NIH HHS / CA / R01 CA054053-10
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Papillomavirus Vaccines
  • [Number-of-references] 91
  • [Other-IDs] NLM/ NIHMS180665; NLM/ PMC2871537
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45. Mikhail MW, Al-Bursheed KM, Abd El-Halim AS, Morsy TA: Studies on mosquito borne dieases in Egypt and Qatar. J Egypt Soc Parasitol; 2009 Dec;39(3):745-56
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  • Anopheles multicolor and A. stephensi were mainly in Al Shamal with low density in Al Rayyan (only in Ain-Khalid locution).

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  • (PMID = 20120742.001).
  • [ISSN] 1110-0583
  • [Journal-full-title] Journal of the Egyptian Society of Parasitology
  • [ISO-abbreviation] J Egypt Soc Parasitol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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46. Bernstein H, Holubec H, Bernstein C, Ignatenko N, Gerner E, Dvorak K, Besselsen D, Ramsey L, Dall'Agnol M, Blohm-Mangone KA, Padilla-Torres J, Cui H, Garewal H, Payne CM: Unique dietary-related mouse model of colitis. Inflamm Bowel Dis; 2006 Apr;12(4):278-93
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  • METHODS: Wild-type B6.129 mice were fed an AIN-93G diet, either supplemented with 0.2% DOC or unsupplemented and sacrificed at 1 week, 1 month, 3 months, 4 months, and 8 months.
  • Genes that play a central role in inflammation and angiogenesis and other related processes such as epithelial barrier function, oxidative stress, apoptosis, cell proliferation/cell cycle/DNA repair, membrane transport, and the ubiquitin-proteasome pathway showed altered expression in the DOC-fed mice compared with the control mice.

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  • (PMID = 16633050.001).
  • [ISSN] 1078-0998
  • [Journal-full-title] Inflammatory bowel diseases
  • [ISO-abbreviation] Inflamm. Bowel Dis.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA72008
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dietary Fats; 0 / Proliferating Cell Nuclear Antigen; 9007-49-2 / DNA
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47. Ely B, Gustafson RA, Karnsakul W: Pseudoprune-belly syndrome in vertebral abnormalities, anal atresia, cardiac abnormalities, tracheoesophageal fistula and/or esophageal atresia, renal agenesis and dysplasia, and limb defects association. Clin Gastroenterol Hepatol; 2008 Jul;6(7):e26
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  • [Title] Pseudoprune-belly syndrome in vertebral abnormalities, anal atresia, cardiac abnormalities, tracheoesophageal fistula and/or esophageal atresia, renal agenesis and dysplasia, and limb defects association.
  • [MeSH-major] Anus, Imperforate. Esophageal Atresia. Heart Defects, Congenital. Kidney / abnormalities. Limb Deformities, Congenital. Prune Belly Syndrome / complications. Spine / abnormalities. Tracheoesophageal Fistula


48. Jawas A, Hammad F, Eid HO, Abu-Zidan FM: Vascular injuries following road traffic collisions in a high-income developing country: a prospective cohort study. World J Emerg Surg; 2010;5:13
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  • METHODS: Data were collected prospectively on road traffic collision injuries in the whole city of Al-Ain, United Arab Emirates, from April 2006 to October 2007 with full details of mechanism of injury and its relation to sustained injuries.
  • CONCLUSIONS: The incidence of hospitalized vascular injury due to road traffic collisions in Al-Ain city is 1.87 cases/100 000 inhabitants.

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  • (PMID = 20482814.001).
  • [ISSN] 1749-7922
  • [Journal-full-title] World journal of emergency surgery : WJES
  • [ISO-abbreviation] World J Emerg Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2892435
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49. Kurihara N, Fan K, Thaler HT, Yang K, Lipkin M: Effect of a Western-style diet fortified with increased calcium and vitamin D on mammary gland of C57BL/6 mice. J Med Food; 2008 Jun;11(2):201-6
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  • The percentage of small ducts increased in WD compared to AIN-76A controls (23.3% vs. 17.4%) but was lower in the WD(y) (17.1%) and WD(CaD) (14.8%) groups.
  • WD mice had higher numbers of epithelial cells per duct than WD(y) (33.2 vs. 27.4, P <.001) and WD(CaD) (33.2 vs. 27.8, P <.001) mice, and AIN-76A-fed mice had higher numbers than WD(y) (31.1 vs. 27.4, P <.005) or WD(CaD) (31.1 vs. 27.8, P <.01) mice.
  • [MeSH-minor] Animals. Apoptosis / drug effects. Cell Count. Epithelial Cells. Female. Mice. Mice, Inbred C57BL. Mitosis / drug effects

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  • (PMID = 18358070.001).
  • [ISSN] 1557-7600
  • [Journal-full-title] Journal of medicinal food
  • [ISO-abbreviation] J Med Food
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 1406-16-2 / Vitamin D; SY7Q814VUP / Calcium
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50. Bener A, Lestringant GG, Ehlayel MS, Saarinen K, Takiddin AH: Treatment outcome of acne vulgaris with oral isotretinoin. J Coll Physicians Surg Pak; 2009 Jan;19(1):49-51
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  • PLACE AND DURATION OF STUDY: Al-Ain Medical District, Tawam Hospital, United Arab Emirates, from 1994 to 2002.

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  • (PMID = 19149981.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 0 / Cholesterol, HDL; 0 / Cholesterol, LDL; 0 / Dermatologic Agents; 0 / Triglycerides; 97C5T2UQ7J / Cholesterol; EH28UP18IF / Isotretinoin
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51. Mullerat J, Perrett CW, Deroide F, Winslet MC, Bofill M, Poulters LW: The role of macrophages in angiogenesis. Comparison between HIV+ and HIV- populations with anal dysplasia and anal cancer. Anticancer Res; 2005 Mar-Apr;25(2A):693-9
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  • [Title] The role of macrophages in angiogenesis. Comparison between HIV+ and HIV- populations with anal dysplasia and anal cancer.
  • BACKGROUND: While macrophages (CD68+) have been associated with angiogenesis in some inflammatory and neoplastic processes by increasing the release of vascular endothelial growth factor (VEGF), their role in anal intraepithelial neoplasia (AIN) and anal squamous cell carcinoma has not been established.
  • This study records macrophage infiltration in anal pre-invasive and invasive lesions in HIV+ and HIV- populations, and determines their relationship with angiogenesis.
  • MATERIALS AND METHODS: Sixty patients (31 HIV+) with AIN and anal SCC were studied.
  • [MeSH-major] Anus Neoplasms / blood supply. Anus Neoplasms / virology. Carcinoma, Squamous Cell / blood supply. Carcinoma, Squamous Cell / virology. HIV Infections / pathology. Macrophages / physiology. Neovascularization, Pathologic / virology
  • [MeSH-minor] Anal Canal / blood supply. Anal Canal / pathology. Antigens, CD / biosynthesis. Antigens, Differentiation, Myelomonocytic / biosynthesis. Anus Diseases / pathology. Anus Diseases / virology. Disease Progression. Humans. Immunohistochemistry. Precancerous Conditions / blood supply. Precancerous Conditions / virology. Vascular Endothelial Growth Factor A / biosynthesis. Warts / pathology. Warts / virology

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  • (PMID = 15868898.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Vascular Endothelial Growth Factor A
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52. Awad HA, Farid TM, Khafagy SM, Nofal RI: Bone mineral content measured by DEXA scan in preterm neonates receiving total parentral nutrition with and without phosphorus supplementation. Pak J Biol Sci; 2010 Sep 15;13(18):891-5
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  • [Title] Bone mineral content measured by DEXA scan in preterm neonates receiving total parentral nutrition with and without phosphorus supplementation.
  • So we aimed to prove the positive effect of adding intravenous phosphorus to total parentral nutrition (TPN) on calcium (Ca) and phosphorus (PO4) metabolism ofpreterm neonates by measuring bone mineral content (BMC) using DEXA scan.
  • A case-control study was conducted in NICU of Obstetric and Gynecology Hospital of Ain Shams University which is a tertiary care unit in Cairo.
  • [MeSH-major] Bone Density. Infant, Premature. Parenteral Nutrition, Total. Phosphorus / administration & dosage

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  • (PMID = 23350162.001).
  • [ISSN] 1028-8880
  • [Journal-full-title] Pakistan journal of biological sciences : PJBS
  • [ISO-abbreviation] Pak. J. Biol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 27YLU75U4W / Phosphorus
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53. Castilho PC, Gouveia SC, Rodrigues AI: Quantification of artemisinin in Artemisia annua extracts by 1H-NMR. Phytochem Anal; 2008 Jul-Aug;19(4):329-34
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  • The ain of this study was to develop a simple protocol for the quantification of artemisinin in a plant extract using an (1)H-NMR method.

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  • (PMID = 18197598.001).
  • [ISSN] 1099-1565
  • [Journal-full-title] Phytochemical analysis : PCA
  • [ISO-abbreviation] Phytochem Anal
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Artemisinins; 0 / Plant Extracts; 0 / Protons; 9RMU91N5K2 / artemisinine
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54. Goldstone SE, Moshier E: Detection of oncogenic human papillomavirus impacts anal screening guidelines in men who have sex with men. Dis Colon Rectum; 2010 Aug;53(8):1135-42
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  • [Title] Detection of oncogenic human papillomavirus impacts anal screening guidelines in men who have sex with men.
  • PURPOSE: It has been shown that testing for oncogenic human papillomavirus (HPV+) improves the sensitivity of cytologic diagnosis of atypical cells of undetermined significance in the cervix and anus, reducing the number of patients requiring colposcopy or high-resolution anoscopy.
  • We endeavored to determine whether HPV testing could predict future high-grade dysplasia (high-grade squamous intraepithelial lesions) and modify screening internals.
  • METHODS: This investigation was conducted via a retrospective chart review of subjects with atypical cells of undetermined significance anal cytology, high-resolution anoscopy, and HPV testing.
  • Of 224 subjects monitored for >2 years, the hazard ratio for developing high-grade dysplasia was 77% less for men who have sex with men who never had oncogenic HPV (HPV-) vs those who stayed HPV+ (P < .013).
  • The hazard ratio for high-grade dysplasia in those who were HPV- vs those who became HPV- was not different.
  • Risk of high-grade dysplasia was 28% within 6 months of becoming HPV+.
  • The 3-year high-grade dysplasia risk was 15% and 54% for HPV- vs HPV+ subjects (P = .0006).
  • Frequency of high-grade dysplasia in subjects who remained HPV- with predominantly atypical cells of undetermined significance cytology for 1, 2, or 3 years was 2%, 0% and 0% and was 17%, 0%, and 0% in HIV+ subjects.
  • Kaplan-Meier analysis for HIV- subjects with HPV- predominantly atypical cells of undetermined significance cytology for 1 year showed <5% incidence of high-grade dysplasia at 4 years.
  • CONCLUSIONS: Change in HPV status can predict the risk of high-grade dysplasia.
  • Subjects with predominantly HPV- atypical cells of undetermined significance cytology for 2 years have a decreased risk of high-grade dysplasia.
  • HPV testing when screening for anal dysplasia could alter screening parameters.
  • [MeSH-major] Anus Neoplasms / diagnosis. Homosexuality, Male. Mass Screening / standards. Papillomaviridae / isolation & purification. Papillomavirus Infections / diagnosis. Practice Guidelines as Topic. Tumor Virus Infections / diagnosis
  • [MeSH-minor] Adult. Anal Canal / pathology. Anal Canal / virology. Colonoscopy. Follow-Up Studies. HIV Seropositivity. Humans. Incidence. Male. Precancerous Conditions. Predictive Value of Tests. Retrospective Studies. United States / epidemiology


55. Joaquim AI, Mendes GE, Ribeiro PF, Baptista MA, Burdmann EA: Ga-67 scintigraphy in the differential diagnosis between acute interstitial nephritis and acute tubular necrosis: an experimental study. Nephrol Dial Transplant; 2010 Oct;25(10):3277-82
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  • [Title] Ga-67 scintigraphy in the differential diagnosis between acute interstitial nephritis and acute tubular necrosis: an experimental study.
  • BACKGROUND: The differentiation between acute interstitial nephritis (AIN) and acute tubular necrosis (ATN) is crucial in patients with acute kidney injury.
  • Gallium-67 citrate (Ga-67) has been used clinically in the differential diagnosis between these entities, but its efficacy is disputed.
  • The aim of this study was to evaluate Ga-67 scintigraphy efficacy in the differentiation between experimental models of drug-induced AIN and ATN.
  • METHODS: Animals were divided into three groups: AIN (n = 8), ATN (n = 8) and control (NL, n = 10).
  • The AIN group received intraperitoneal puromycin aminonucleoside (single dose, 150 mg/kg).
  • RESULTS: Renal Ga-67 uptake was strikingly more intense in the AIN group when compared to the ATN (P < 0.0001) and NL (P < 0.001) groups.
  • The ATN group had increased Cr when compared to the NL group (P < 0.001) and lower urinary osmolality vs the NL (P < 0.001) and AIN (P < 0.01) groups.
  • Renal histology showed severe acute tubular injury in the ATN group and intense interstitial inflammation in the AIN group, and was normal in control animals.
  • CONCLUSION: Ga-67 scintigraphy was extremely effective in the differentiation between experimental drug-induced ATN and AIN.
  • [MeSH-minor] Acute Disease. Acute Kidney Injury / radionuclide imaging. Animals. Diagnosis, Differential. Kidney / pathology. Kidney / physiopathology. Male. Rats. Rats, Wistar

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  • (PMID = 20348147.001).
  • [ISSN] 1460-2385
  • [Journal-full-title] Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • [ISO-abbreviation] Nephrol. Dial. Transplant.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Gallium Radioisotopes
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56. Kreuter A, Brockmeyer NH, Altmeyer P, Wieland U, German Competence Network HIV/AIDS: Anal intraepithelial neoplasia in HIV infection. J Dtsch Dermatol Ges; 2008 Nov;6(11):925-34
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  • [Title] Anal intraepithelial neoplasia in HIV infection.
  • In HIV-infected men who have sex with men (MSM), anal HPV prevalence is more than 90% and infections with multiple HPV types are common.
  • Anal intraepithelial neoplasia (AIN) is a potential precursor lesion of squamous cell carcinoma of the anus.
  • Like its cervical counterpart, cervical intraepithelial neoplasia (CIN), AIN is causally linked to persistent infections with high-risk HPV types such as HPV16 or HPV18.
  • As AIN and CIN share distinct biological similar-ities, AIN screenings analogous to Pap smear programs for CIN have been recommended in high-risk populations to reduce the incidence of anal carcinoma.
  • These screenings include cytological analysis followed by high resolution anoscopy in case of anal dysplasia.
  • Treatment guidelines for AIN are not yet available.
  • However, controlled studies on AIN treatment have not been performed.
  • The impact of HPV vaccination on AIN development will also need to be assessed.
  • [MeSH-major] Anus Neoplasms / diagnosis. Anus Neoplasms / therapy. HIV Infections / diagnosis. HIV Infections / therapy. Papillomavirus Infections / diagnosis. Papillomavirus Infections / therapy. Skin Neoplasms / diagnosis. Skin Neoplasms / therapy

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  • (PMID = 18410393.001).
  • [ISSN] 1610-0387
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] eng; ger
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Number-of-references] 46
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57. Jawas A, Abu-Zidan FM: Management algorithm for complete blunt renal artery occlusion in multiple trauma patients: case series. Int J Surg; 2008 Aug;6(4):317-22
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  • PATIENTS AND METHODS: All blunt trauma patients who had complete renal artery occlusion and were treated at Tawam and Al-Ain Hospitals during 2005-2007 were studied.
  • [MeSH-minor] Adolescent. Adult. Angiography / methods. Child. Cohort Studies. Female. Follow-Up Studies. Humans. Injury Severity Score. Male. Multiple Trauma / diagnosis. Multiple Trauma / mortality. Multiple Trauma / therapy. Registries. Retrospective Studies. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome. United Arab Emirates. Vascular Surgical Procedures / methods

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  • (PMID = 18590988.001).
  • [ISSN] 1743-9159
  • [Journal-full-title] International journal of surgery (London, England)
  • [ISO-abbreviation] Int J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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58. Inomata S, Watanabe A, Nomura M, Ando T: Mating communication systems of four Plusiinae species distributed in Japan: identification of the sex pheromones and field evaluation. J Chem Ecol; 2005 Jun;31(6):1429-42
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  • The sex pheromones of four Plusiinae species in the family Noctuidae, Ctenoplusia albostriata (CA), Macdunnoughia purissima (MP), Syngrapha ain (SA), and Diachrysia stenochrysis (DS) were identified by GC-EAD and GC-MS analyses.

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59. Witecka J, Auguściak-Duma AM, Kruczek A, Szydło A, Lesiak M, Krzak M, Pietrzyk JJ, Männikkö M, Sieroń AL: Two novel COL1A1 mutations in patients with osteogenesis imperfecta (OI) affect the stability of the collagen type I triple-helix. J Appl Genet; 2008;49(3):283-95
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  • Osteogenesis imperfecta (OI) is a bone dysplasia caused by mutations in the COL1A1 and COL1A2 genes.
  • One caused a substitution of glycine 200 by valine at the N-terminus of D1 in OI type I/IV, lowering collagen stability by 50% at 34 degrees C.

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  • (PMID = 18670065.001).
  • [ISSN] 1234-1983
  • [Journal-full-title] Journal of applied genetics
  • [ISO-abbreviation] J. Appl. Genet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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60. Figurska-Ciura D, Orzeł D, Styczyńska M, Wacław L, Zechałko-Czajkowska A: [The influence of RS4 resistant starch on wistar rats metabolism. Biochemical and lipid indices]. Rocz Panstw Zakl Hig; 2007;58(1):1-6
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  • Control rats were feed ad libitum with standarised synthetic diet AIN-93.

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  • (PMID = 17711083.001).
  • [ISSN] 0035-7715
  • [Journal-full-title] Roczniki Państwowego Zakładu Higieny
  • [ISO-abbreviation] Rocz Panstw Zakl Hig
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Cholesterol, HDL; 0 / Dietary Carbohydrates; 0 / Fatty Acids; 0 / Triglycerides; 9005-25-8 / Starch; 97C5T2UQ7J / Cholesterol
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61. Hofmeister EP, Moran SL, Shin AY: Anterior and posterior interosseous neurectomy for the treatment of chronic dynamic instability of the wrist. Hand (N Y); 2006 Dec;1(2):63-70
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  • The purpose of this study was to determine the results of combined anterior and posterior interosseous neurectomy (AIN/PIN) in patients with chronic wrist pain secondary to dynamic instability, and to determine the predictability of selective AIN/PIN blocks with respect to pain relief, grip strength, and outcome of the neurectomy.
  • Inclusion criteria were patients with arthroscopically confirmed dynamic wrist instability who had undergone a diagnostic AIN/PIN injection, followed by a single dorsal incision neurectomy.
  • The results of AIN/PIN neurectomy demonstrate that it may be an effective alternative to wrist salvage or reconstructive procedures within the first few years of follow-up.

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  • [ISSN] 1558-9447
  • [Journal-full-title] Hand (New York, N.Y.)
  • [ISO-abbreviation] Hand (N Y)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2526030
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62. Shim JY, Kim KO, Seo BH, Lee HS: Soybean isoflavone extract improves glucose tolerance and raises the survival rate in streptozotocin-induced diabetic rats. Nutr Res Pract; 2007;1(4):266-72
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  • One group of normal rats (normal control) was fed an AIN-76-based experimental diet and four groups of diabetic rats were fed the same diet supplemented with four different levels of soybean isoflavone extract for seven weeks.

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  • (PMID = 20368949.001).
  • [ISSN] 2005-6168
  • [Journal-full-title] Nutrition research and practice
  • [ISO-abbreviation] Nutr Res Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2849033
  • [Keywords] NOTNLM ; Soybean isoflavone extract / diabetic rat / glucose tolerance / streptozotocin / survival rate
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63. Elnour AA, Ellahham NH, Al Qassas HI: Raising the awareness of inpatient nursing staff about medication errors. Pharm World Sci; 2008 Apr;30(2):182-90
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  • METHOD: A sample of in-patient nursing staff in Al Ain hospital (n = 370) was included in the study and completed a self-reported questionnaire about medication errors.

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  • (PMID = 17882532.001).
  • [ISSN] 0928-1231
  • [Journal-full-title] Pharmacy world & science : PWS
  • [ISO-abbreviation] Pharm World Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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64. Dave B, Eason RR, Geng Y, Su Y, Badger TM, Simmen RC: Tp53-associated growth arrest and DNA damage repair gene expression is attenuated in mammary epithelial cells of rats fed whey proteins. J Nutr; 2006 May;136(5):1156-60
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  • [Title] Tp53-associated growth arrest and DNA damage repair gene expression is attenuated in mammary epithelial cells of rats fed whey proteins.
  • The present study examined the modulatory effects of dietary intake of whey protein hydrolysate (WPH) relative to casein (CAS), on mammary epithelial cell resistance to endogenous DNA damage using Tp53 gene expression and signaling as a read-out, and on systemic proapoptotic and immune surveillance activity, in young adult female Sprague-Dawley rats.
  • Rats were fed AIN-93G diets made with CAS or WPH as the sole protein source beginning at gestation d 4.
  • [MeSH-major] DNA Damage. DNA Repair. Epithelial Cells / physiology. Gene Expression Regulation / physiology. Mammary Glands, Animal / cytology. Milk Proteins / pharmacology. Tumor Suppressor Protein p53 / genetics

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  • (PMID = 16614397.001).
  • [ISSN] 0022-3166
  • [Journal-full-title] The Journal of nutrition
  • [ISO-abbreviation] J. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Milk Proteins; 0 / Tumor Suppressor Protein p53; 0 / Whey Proteins; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases
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65. Wang L, Ha CL, Cheng TL, Cheng SY, Lian TW, Wu MJ: Oral administration of submerged cultivated Grifola frondosa enhances phagocytic activity in normal mice. J Pharm Pharmacol; 2008 Feb;60(2):237-43
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  • After feeding 8-week-old female BALB/cByJ mice with AIN-93G diet containing 0% (C), 1% (G1), 3% (G3) or 5% (G5) (wt/wt) G. frondosa mixture for 31 days, neither body weight nor the outward appearance of organs showed any significant difference among different diet groups.

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  • (PMID = 18237472.001).
  • [ISSN] 0022-3573
  • [Journal-full-title] The Journal of pharmacy and pharmacology
  • [ISO-abbreviation] J. Pharm. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Carbohydrates; 0 / Cytokines; K72T3FS567 / Adenosine
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66. Forcier M, Musacchio N: An overview of human papillomavirus infection for the dermatologist: disease, diagnosis, management, and prevention. Dermatol Ther; 2010 Sep-Oct;23(5):458-76
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  • [Title] An overview of human papillomavirus infection for the dermatologist: disease, diagnosis, management, and prevention.
  • Genital human papillomavirus (HPV) is a common, usually transient, dermatologic infection transmitted by genital contact that can cause a variety of anogenital diseases, including warts (condyloma), dysplasia (cervical, vaginal, vulvar, anal), and squamous cell carcinoma.
  • [MeSH-major] Condylomata Acuminata / diagnosis. Condylomata Acuminata / therapy. Papillomavirus Infections. Vaginal Neoplasms / virology. Vulvar Neoplasms / virology
  • [MeSH-minor] Disease Progression. Early Detection of Cancer. Female. Humans. Male. Papillomaviridae / pathogenicity. Papillomavirus Vaccines / administration & dosage. Uterine Cervical Neoplasms / diagnosis. Uterine Cervical Neoplasms / prevention & control. Uterine Cervical Neoplasms / virology

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  • [Copyright] © 2010 Wiley Periodicals, Inc.
  • (PMID = 20868401.001).
  • [ISSN] 1529-8019
  • [Journal-full-title] Dermatologic therapy
  • [ISO-abbreviation] Dermatol Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Papillomavirus Vaccines
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67. Kaczorowska-Hać B, Wierzba J, Stefanowicz J, Sielachowicz K, Wlazłowski M, Balcerska A: [Neutropenia in infancy - sometimes chronic and benign - own experiences]. Med Wieku Rozwoj; 2008 Jul-Sep;12(3):767-70
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  • The most common type of chronic neutropenia in infants is chronic, benign neutropenia (AIN).
  • [MeSH-major] Neutropenia / blood. Neutropenia / diagnosis

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  • (PMID = 19305028.001).
  • [Journal-full-title] Medycyna wieku rozwojowego
  • [ISO-abbreviation] Med Wieku Rozwoj
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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68. Beattie GC, Paul I, Calvert CH: Endoscopic transanal resection of rectal tumours using a urological resectoscope--still has a role in selected patients. Colorectal Dis; 2005 Jan;7(1):47-50
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  • Histopathology revealed rectal adenoma (with varying degrees of dysplasia) in 11 (55%) patients and adenocarcinoma in 9 (45%).
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Anal Canal / surgery. Proctoscopy. Rectal Neoplasms / surgery. Urologic Surgical Procedures / instrumentation

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  • (PMID = 15606584.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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69. Shen B, Fazio VW, Remzi FH, Lashner BA: Clinical approach to diseases of ileal pouch-anal anastomosis. Am J Gastroenterol; 2005 Dec;100(12):2796-807
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  • [Title] Clinical approach to diseases of ileal pouch-anal anastomosis.
  • Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical treatment of choice for ulcerative colitis (UC) patients with medically refractory disease or dysplasia.
  • Accurate diagnosis and classification are important for appropriate management.
  • Endoscopic evaluation is the most important tool for the diagnosis and differential diagnosis.
  • [MeSH-minor] Adrenal Cortex Hormones / therapeutic use. Anti-Bacterial Agents / therapeutic use. Colonoscopy / methods. Crohn Disease / drug therapy. Crohn Disease / pathology. Drug Therapy, Combination. Female. Humans. Irritable Bowel Syndrome / diagnosis. Irritable Bowel Syndrome / drug therapy. Male. Prognosis. Risk Assessment. Severity of Illness Index. Treatment Outcome

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  • (PMID = 16393238.001).
  • [ISSN] 0002-9270
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R03 DK 067275
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Anti-Bacterial Agents
  • [Number-of-references] 97
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70. Lau BY, Ward WE, Kang JX, Ma DW: Femur EPA and DHA are correlated with femur biomechanical strength in young fat-1 mice. J Nutr Biochem; 2009 Jun;20(6):453-61
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  • Control and fat-1 mice were fed an AIN-93G diet containing 10% safflower oil from weaning through 12 weeks of age.
  • The n-6/n-3 PUFA ratio in the femur was negatively correlated with BMC (r=-.57, P=.01) and peak load at femur midpoint (r=-.53, P=.02) and femur neck (r=-.52, P=.02).

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  • (PMID = 18708283.001).
  • [ISSN] 1873-4847
  • [Journal-full-title] The Journal of nutritional biochemistry
  • [ISO-abbreviation] J. Nutr. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Caenorhabditis elegans Proteins; 0 / fat-1 protein, C elegans; 25167-62-8 / Docosahexaenoic Acids; AAN7QOV9EA / Eicosapentaenoic Acid; EC 1.14.19.- / Fatty Acid Desaturases
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71. Wainwright PE, Lomanowska AM, McCutcheon D, Park EJ, Clandinin MT, Ramanujam KS: Postnatal dietary supplementation with either gangliosides or choline: effects on spatial short-term memory in artificially-reared rats. Nutr Neurosci; 2007 Feb-Apr;10(1-2):67-77
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  • Rats were weaned onto AIN 93G diet and on PD 35 were trained on a cued delayed- matching-to-place version of the Morris water maze.

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  • (PMID = 17539485.001).
  • [ISSN] 1028-415X
  • [Journal-full-title] Nutritional neuroscience
  • [ISO-abbreviation] Nutr Neurosci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Gangliosides; N91BDP6H0X / Choline
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72. Potack J, Itzkowitz SH: Colorectal cancer in inflammatory bowel disease. Gut Liver; 2008 Sep;2(2):61-73
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  • To reduce CRC mortality in IBD, colonoscopic surveillance remains the major way to detect early mucosal dysplasia.
  • When dysplasia is confirmed, proctocolectomy is considered for these patients.
  • Ulcerative colitis patients with total proctocolectomy and ileal pouch anal-anastomosis have a rather low risk of dysplasia in the ileal pouch, but the anal transition zone should be monitored periodically.
  • New endoscopic and molecular screening approaches may further refine our current surveillance guidelines and our understanding of the natural history of dysplasia.

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  • (PMID = 20485613.001).
  • [ISSN] 2005-1212
  • [Journal-full-title] Gut and liver
  • [ISO-abbreviation] Gut Liver
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2871581
  • [Keywords] NOTNLM ; Colorectal neoplasms / Dysplasia / Inflammatory bowel disease
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73. Kim MJ, Heim M, Mayr M: Effect of corticosteroids during ongoing drug exposure in pantoprazole-induced interstitial nephritis. Nephrol Dial Transplant; 2010 May;25(5):1716-9
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  • Acute interstitial nephritis (AIN) represents a significant cause of acute renal failure in hospital practice.
  • An increasing number of drugs are known to cause AIN.
  • Early diagnosis of interstitial nephritis by renal biopsy and identification of the causative drug and its withdrawal remains the mainstay of treatment.

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  • (PMID = 20067906.001).
  • [ISSN] 1460-2385
  • [Journal-full-title] Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • [ISO-abbreviation] Nephrol. Dial. Transplant.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 2-Pyridinylmethylsulfinylbenzimidazoles; 0 / Proton Pump Inhibitors; D8TST4O562 / pantoprazole; VB0R961HZT / Prednisone
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74. Murphy N, Ring M, Heffron CC, King B, Killalea AG, Hughes C, Martin CM, McGuinness E, Sheils O, O'Leary JJ: p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer. J Clin Pathol; 2005 May;58(5):525-34
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  • [Title] p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer.
  • AIM: To analyse and compare expression patterns of three potential biomarkers-p16(INK4A), CDC6, and MCM5-and evaluate their use as predictive biomarkers in squamous and glandular cervical preinvasive neoplasia.
  • METHODS: Immunocytochemical analysis of p16(INK4A), MCM5, and CDC6 expression was performed on 20 normal, 38 cervical intraepithelial neoplasia 1 (CIN1), 33 CIN2, 46 CIN3, 10 squamous cell carcinoma, 19 cervical glandular intraepithelial neoplasia (cGIN), and 10 adenocarcinoma samples.
  • RESULTS: All three markers showed a linear correlation between expression and grade of dysplasia. p16(INK4A) and MCM5 protein expression was upregulated in all grades of squamous and glandular dysplasia.
  • CDC6 protein was preferentially expressed in high grade lesions and in invasive squamous cell carcinoma.
  • CONCLUSION: p16(INK4A) expression was closely associated with high risk HPV infection-all grades of squamous and glandular cervical lesions were immunohistochemically positive.
  • MCM5 staining intensity was independent of high risk HPV infection, highlighting its potential as a biomarker in both HPV dependent and independent cervical dysplasia.
  • CDC6 may be a biomarker of high grade and invasive lesions of the cervix, with limited use in low grade dysplasia. p16(INK4A) was the most reliable marker of cervical dysplasia.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cell Cycle Proteins / analysis. Cervical Intraepithelial Neoplasia / chemistry. Cyclin-Dependent Kinase Inhibitor p16 / analysis. DNA-Binding Proteins / analysis. Nuclear Proteins / analysis. Schizosaccharomyces pombe Proteins / analysis. Uterine Cervical Neoplasms / chemistry
  • [MeSH-minor] Adenocarcinoma / chemistry. Adenocarcinoma / complications. Adenocarcinoma / immunology. Antibodies, Monoclonal / immunology. Blotting, Western / methods. Carcinoma, Squamous Cell / chemistry. Carcinoma, Squamous Cell / complications. Carcinoma, Squamous Cell / immunology. Female. Humans. Immunohistochemistry / methods. Neoplasm Proteins / analysis. Neoplasm Proteins / immunology. Papillomaviridae / isolation & purification. Papillomavirus Infections / complications. Papillomavirus Infections / diagnosis. Risk Factors

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  • (PMID = 15858126.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Biomarkers, Tumor; 0 / CDC6 protein, human; 0 / Cell Cycle Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA-Binding Proteins; 0 / Neoplasm Proteins; 0 / Nuclear Proteins; 0 / Schizosaccharomyces pombe Proteins; 0 / mcm5 protein, S pombe
  • [Other-IDs] NLM/ PMC1770660
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75. Sanclemente G, Herrera S, Tyring SK, Rady PL, Zuleta JJ, Correa LA, He Q, Wolff JC: Human papillomavirus (HPV) viral load and HPV type in the clinical outcome of HIV-positive patients treated with imiquimod for anogenital warts and anal intraepithelial neoplasia. J Eur Acad Dermatol Venereol; 2007 Sep;21(8):1054-60
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  • [Title] Human papillomavirus (HPV) viral load and HPV type in the clinical outcome of HIV-positive patients treated with imiquimod for anogenital warts and anal intraepithelial neoplasia.
  • OBJECTIVE: To evaluate the efficacy of 5% imiquimod in HIV-positive male patients with anogenital warts or anal intraepithelial neoplasia (AIN), and to elucidate whether human papillomavirus (HPV) type and viral load were important for clinical outcome and recurrences.
  • METHODS: Thirty-seven patients with histologically proven anogenital warts or AIN were enrolled.
  • The perianal area was the main lesion location.
  • Eighteen patients had a histopathological diagnosis of AIN-1.
  • CONCLUSIONS: The assumption that visible perianal warts are benign lesions in HIV-positive patients has to be reevaluated since an important number of such lesions could correspond to low-grade anal disease, which in turn could progress to high-grade anal disease or cancer.
  • In addition, our results in this preliminary study indicate that imiquimod appears to be effective in treating AIN in HIV-positive patients.
  • Further studies are needed to document its utility to prevent high-grade dysplasia and/or anal cancer.
  • [MeSH-major] AIDS-Related Opportunistic Infections / drug therapy. Adjuvants, Immunologic / therapeutic use. Aminoquinolines / therapeutic use. Anus Diseases / drug therapy. Anus Neoplasms / drug therapy. Condylomata Acuminata / drug therapy. Genital Diseases, Male / drug therapy. Papillomavirus Infections / drug therapy


76. Garcia-Barceló MM, Wong KK, Lui VC, Yuan ZW, So MT, Ngan ES, Miao XP, Chung PH, Khong PL, Tam PK: Identification of a HOXD13 mutation in a VACTERL patient. Am J Med Genet A; 2008 Dec 15;146A(24):3181-5
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  • It is comprised of vertebral defects (V), anal atresia (A), cardiac anomaly (C), tracheoesophageal fistula with esophageal atresia (TE), renal dysplasia (R) and limb lesions (L).
  • [MeSH-minor] Adolescent. Amino Acid Sequence. Anus, Imperforate / complications. Anus, Imperforate / genetics. Base Sequence. DNA Mutational Analysis. Esophageal Atresia / complications. Esophageal Atresia / genetics. Female. Heart Defects, Congenital / complications. Heart Defects, Congenital / genetics. Humans. Limb Deformities, Congenital / complications. Limb Deformities, Congenital / genetics. Limb Deformities, Congenital / radiography. Molecular Sequence Data. Syndrome. Tracheoesophageal Fistula / complications. Tracheoesophageal Fistula / genetics

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  • [Copyright] Copyright (c) 2008 Wiley-Liss, Inc.
  • (PMID = 19006232.001).
  • [ISSN] 1552-4833
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HOXD13 protein, human; 0 / Homeodomain Proteins; 0 / Transcription Factors
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77. Yan L, DeMars LC: Effects of dietary fat on spontaneous metastasis of Lewis lung carcinoma in mice. Clin Exp Metastasis; 2010 Dec;27(8):581-90
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  • Three-week old male C57BL/6 mice were fed the AIN-93G diet or a 45% fat diet (% kcal.) for 7 weeks before they were subcutaneously injected with 2.5 × 10⁵ viable carcinoma cells.
  • The high-fat diet significantly increased body weight and abdominal adipose weight compared to the AIN-93G diet.
  • Feeding mice the 45% fat diet resulted in a two-fold increase in the number of lung metastases (P < 0.05), a 35% increase in tumor cross-sectional area, and a 50% increase in tumor volume compared to mice fed the AIN-93G diet.
  • There were no differences in plasma concentrations of TIMP-1, IL-1β, VEGF and MCP-1 in non-tumor-bearing mice fed the AIN-93G diet or the high-fat diet, but significant increases in these cytokines in tumor-bearing mice fed the AIN-93G diet compared to the non-tumor-bearing mice fed the same diet (P < 0.05 for each comparison).
  • Further significant increases in these cytokines in tumor-bearing mice fed the 45% fat diet compared to the same tumor-bearing mice fed the AIN-93G diet (P < 0.05 for each comparison).
  • The high-fat diet significantly increased plasma leptin and significantly decreased plasma adiponectin compared to the AIN-93G diet in both non-tumor-bearing and tumor-bearing mice.

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  • (PMID = 20697780.001).
  • [ISSN] 1573-7276
  • [Journal-full-title] Clinical & experimental metastasis
  • [ISO-abbreviation] Clin. Exp. Metastasis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cytokines; 0 / Dietary Fats
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78. Król E, Krejpcio Z: Chromium(III) propionate complex supplementation improves carbohydrate metabolism in insulin-resistance rat model. Food Chem Toxicol; 2010 Oct;48(10):2791-6
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  • Animals were fed at libitum: the control diet (AIN-93M), and high-fructose diets (HF) containing various levels of Cr(III) given as CrProp (1 mg Cr kg(-1) diet (HF) and supplemented with 10 mg Cr kg(-1) diet (HFCr10), or 50 mg Cr kg(-1) diet (HFCr50), equal to approx.

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  • [Copyright] Copyright (c) 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20633590.001).
  • [ISSN] 1873-6351
  • [Journal-full-title] Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • [ISO-abbreviation] Food Chem. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Hypoglycemic Agents; 0 / Insulin; 0 / Metals; 0 / Propionates; 30237-26-4 / Fructose; 79-09-4 / propionic acid
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79. Matsumoto K, Yokoyama S, Gato N: Bile acid-binding activity of young persimmon (Diospyros kaki) fruit and its hypolipidemic effect in mice. Phytother Res; 2010 Feb;24(2):205-10
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  • In an animal experiment, male C57BL/6.Cr mice (n = 5) were fed an AIN-76-modified high fat diet supplemented with 2% or 5% (w/w) dried young persimmon fruit (YP) for 10 weeks.

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  • [Copyright] (c) 2009 John Wiley & Sons, Ltd.
  • (PMID = 19585467.001).
  • [ISSN] 1099-1573
  • [Journal-full-title] Phytotherapy research : PTR
  • [ISO-abbreviation] Phytother Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bile Acids and Salts; 0 / Dietary Fats; 0 / Hypolipidemic Agents; 0 / Proanthocyanidins; 0 / Triglycerides; 97C5T2UQ7J / Cholesterol; G1JO7801AE / Cholic Acid
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80. Williams D, Verghese M, Walker LT, Boateng J, Shackelford L, Chawan CB: Flax seed oil and flax seed meal reduce the formation of aberrant crypt foci (ACF) in azoxymethane-induced colon cancer in Fisher 344 male rats. Food Chem Toxicol; 2007 Jan;45(1):153-9
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  • Following an acclimatization period, rats were divided into six groups and fed AIN 93G diet Control (C), C+7 and 14% soybean oil (SBO), C+7 and 14% flax seed oil (FSO) and C+10 and 20% flax seed meal (FSM).

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  • (PMID = 17045379.001).
  • [ISSN] 0278-6915
  • [Journal-full-title] Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • [ISO-abbreviation] Food Chem. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Dietary Fats, Unsaturated; 0 / Oils; 8001-22-7 / Soybean Oil; 8001-26-1 / Linseed Oil; EC 2.5.1.18 / Glutathione Transferase; MO0N1J0SEN / Azoxymethane
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81. Hwang H, Chen T, Nines RG, Shin HC, Stoner GD: Photochemoprevention of UVB-induced skin carcinogenesis in SKH-1 mice by brown algae polyphenols. Int J Cancer; 2006 Dec 15;119(12):2742-9
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  • They were treated orally (0.1% and 0.5% with AIN-76 diet, w/w) and topically (3 and 6 mg/0.2 ml of vehicle) with brown algae polyphenols and irradiated with UVB for 26 weeks.

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  • [Copyright] Copyright 2006 Wiley-Liss, Inc.
  • (PMID = 17019718.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzofurans; 0 / Dioxins; 0 / Flavonoids; 0 / Phenols; 0 / Polyphenols; 0 / Proliferating Cell Nuclear Antigen; 0 / dieckol; 88095-81-2 / 6,6'-bieckol; 88798-74-7 / eckol; EC 1.14.99.1 / Cyclooxygenase 2; K7Q1JQR04M / Dinoprostone
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82. Mukhopadhyay S, Guillory B, Mukherjee S, Das SK: Antiproliferative effect of peripheral benzodiazepine receptor antagonist PK11195 in rat mammary tumor cells. Mol Cell Biochem; 2010 Jul;340(1-2):203-13
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  • Breast tumors were induced by administration of a carcinogen, dimethylbenz[a]anthracene to 50-day-old female rats maintained on a standard AIN-76A diet with casein as the protein source.

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  • (PMID = 20204676.001).
  • [ISSN] 1573-4919
  • [Journal-full-title] Molecular and cellular biochemistry
  • [ISO-abbreviation] Mol. Cell. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Annexin A5; 0 / Antigens, CD31; 0 / Antineoplastic Agents; 0 / Benzodiazepinones; 0 / Carrier Proteins; 0 / GABA-A Receptor Agonists; 0 / GABA-A Receptor Antagonists; 0 / Isoquinolines; 0 / Ki-67 Antigen; 0 / Proliferating Cell Nuclear Antigen; 0 / Receptors, GABA-A; 0 / Vascular Endothelial Growth Factor A; 0 / vascular endothelial growth factor A, rat; 141440-82-6 / Tspo protein, rat; 2QW0IK1742 / 4'-chlorodiazepam; 57-97-6 / 9,10-Dimethyl-1,2-benzanthracene; YNF83VN1RL / PK 11195
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83. Abdulrazzaq YM, Ibrahim A, Al-Khayat AI, Nagelkerke N, Ali BR: R58fs mutation in the HGD gene in a family with alkaptonuria in the UAE. Ann Hum Genet; 2009 Jan;73(1):125-30
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  • In a 3 stage sampling technique 2981 pupils from Government schools in Al Ain and private schools in Dubai were selected to take part in the study, of whom 2857 provided urine samples.

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  • (PMID = 18945288.001).
  • [ISSN] 1469-1809
  • [Journal-full-title] Annals of human genetics
  • [ISO-abbreviation] Ann. Hum. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 1.13.11.5 / Homogentisate 1,2-Dioxygenase; NP8UE6VF08 / Homogentisic Acid
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84. Moussata D, Nancey S, Lapalus MG, Prost B, Chavaillon A, Bernard G, Ponchon T, Saurin JC: Frequency and severity of ileal adenomas in familial adenomatous polyposis after colectomy. Endoscopy; 2008 Feb;40(2):120-5
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  • BACKGROUND AND STUDY AIMS: The high cumulative risk of colorectal cancer in patients with familial adenomatous polyposis (FAP) justifies prophylactic colectomy with either ileorectal (IRA) or ileal-pouch-anal anastomosis (IPAA).
  • RESULTS: In the IPAA group, 18/23 patients (78 %) presented with visible polyps [histology: 16 (70 %) had adenoma with low-grade dysplasia; 1 (4 %) had adenoma with high-grade dysplasia; 1 had normal mucosa].
  • The mean interval between colectomy and the diagnosis of adenoma was 4.7 +/- 3.3 years.
  • In the IRA group, 16/21 patients (77 %) presented visible polyps in the ileal mucosa [adenoma with low-grade dysplasia in 8 patients (38 %), with high-grade dysplasia in 2 (10 %), and lymphoid nodular hyperplasia in 6].
  • The mean interval between colectomy and adenoma diagnosis was significantly shorter in the IPAA than in the IRA group (4.76 +/- 3.3 vs. 16.4 +/- 8.5 years, P< 0.0001).
  • CONCLUSION: Our results show a high frequency of adenomas in the ileal mucosa of patients with IPAA and IRA (74 % and 48 % respectively), with evolution into high-grade dysplasia in 6.7 % of cases.


85. Walker F, Abramowitz L, Benabderrahmane D, Duval X, Descatoire V, Hénin D, Lehy T, Aparicio T: Growth factor receptor expression in anal squamous lesions: modifications associated with oncogenic human papillomavirus and human immunodeficiency virus. Hum Pathol; 2009 Nov;40(11):1517-27
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  • [Title] Growth factor receptor expression in anal squamous lesions: modifications associated with oncogenic human papillomavirus and human immunodeficiency virus.
  • High prevalence of squamous anal lesions is linked to oncogenic human papillomavirus (HPV).
  • Human immunodeficiency virus (HIV) promotes anal carcinogenesis.
  • Epidermal growth factor receptor (EGFR), HER2/neu, c-Met, and vascular endothelial growth factor receptor-1 (VEGFR1) (tyrosine kinase growth factor receptors) are implicated in tumor progression, but little is known about their role in anal lesions.
  • We investigated their expression and distribution in normal, dysplastic, and carcinomatous anal epithelium and then tried to analyze the effects on these variables of HPV and the HIV-positive status.
  • We studied growth factor receptors, p16 and Ki67 expression, by in situ hybridization, fluorescent in situ hybridization (FISH) and chromogen in situ hybridization (CISH), immunocytochemistry, and morphological quantification in 226 lesions, either infected by HPV6 and 11 (31 condylomas acuminata) or infected with oncogenic HPVs (48 invasive cancers, 147 anal intraepithelial neoplasias).
  • HIV-positive anal cancers showed correlated c-Met and VEGFR1 (P < .003), strong p16 labeling, and an increased Ki67 proliferation.
  • The finding that EGFR, c-Met, and VEGFR1 involved in carcinogenesis are well-represented and coexpressed in anal cancers, especially in HIV-positive population, suggests possible novel targeted treatments for anal diseases.
  • [MeSH-major] Anus Neoplasms / genetics. Anus Neoplasms / virology. Biomarkers, Tumor / analysis. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / virology. Receptors, Growth Factor / biosynthesis


86. Aiyer HS, Kichambare S, Gupta RC: Prevention of oxidative DNA damage by bioactive berry components. Nutr Cancer; 2008;60 Suppl 1:36-42
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  • In this study, ACI rats (8 wk old) were fed either AIN-93M diet or diets supplemented with 0.5% each of mixed berries (strawberry, blueberry, blackberry, and red and black raspberry), blueberry alone (BB; 2.5%), or ellagic acid (EA; 400 ppm) from 2 wk prior to and up to 12 wk of E(2) treatment.

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  • (PMID = 19003579.001).
  • [ISSN] 1532-7914
  • [Journal-full-title] Nutrition and cancer
  • [ISO-abbreviation] Nutr Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA-114118; United States / NCI NIH HHS / CA / CA-90892
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anthocyanins; 0 / DNA Adducts; 0 / Estrogens, Catechol; 0 / Plant Extracts; 19YRN3ZS9P / Ellagic Acid; 4TI98Z838E / Estradiol; 7447-39-4 / cupric chloride; 789U1901C5 / Copper; C3ZO03450E / 4-hydroxyestradiol
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87. Panemangalore M, Bebe FN: Interaction between pesticides and essential metal copper increases the accumulation of copper in the kidneys of rats. Biol Trace Elem Res; 2005;108(1-3):169-84
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  • Male Sprague-Dawley rats, weighing 175-200 g, six per group were fed AIN 93M diet (CON) or diets containing 500 mg Ca (LCa), 7 mg Zn (LZn), 2 mg Cu (LCu), 60 mg Zn (HZn), or 12 mg Cu (HCu) per kilogram of diet in the following combinations: control (CON), LCa+LZn (LC+Z), LCa+LZn+LCu (LC+Z+C), or HZn+HCu (HZ+C) without or with a pesticides mixture (PM); Endosulfan, Thiram, and Acephate were added to the diets at 25% of LD50/kg.

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  • (PMID = 16327070.001).
  • [ISSN] 0163-4984
  • [Journal-full-title] Biological trace element research
  • [ISO-abbreviation] Biol Trace Elem Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Pesticides; 789U1901C5 / Copper; EC 1.16.3.1 / Ceruloplasmin; J41CSQ7QDS / Zinc; SY7Q814VUP / Calcium
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88. Son EW, Lee SR, Choi HS, Koo HJ, Huh JE, Kim MH, Pyo S: Effects of supplementation with higher levels of manganese and magnesium on immune function. Arch Pharm Res; 2007 Jun;30(6):743-9
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  • The treatments were as follows: Group 1, AIN-93M diet (0.05% Mg, 0.001% Mn); Group 2, high-dose Mg (0.1% Mg, 0.001% Mn); and Group 3, high dose Mn (0.05% Mg, 0.01% Mn) (n-12/group).

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  • (PMID = 17679553.001).
  • [ISSN] 0253-6269
  • [Journal-full-title] Archives of pharmacal research
  • [ISO-abbreviation] Arch. Pharm. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / Immunologic Factors; 0 / Indicators and Reagents; 0 / Mitogens; 0 / Reactive Oxygen Species; 31C4KY9ESH / Nitric Oxide; 36015-30-2 / Propidium; 42Z2K6ZL8P / Manganese; I2ZWO3LS3M / Trypan Blue; I38ZP9992A / Magnesium; SY7Q814VUP / Calcium
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89. Amer MS, Wahba HM, Ashmawi SS, Mabrouk RR, Sharaf Eldeen AA, Hamza SA: Proinflammatory cytokines in Egyptian elderly with chronic obstructive pulmonary disease. Lung India; 2010 Oct;27(4):225-9
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  • SETTINGS AND DESIGN: A case control study involving 90 elderly participants from the outpatient clinics of Ain Shams University hospitals.

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  • (PMID = 21139720.001).
  • [ISSN] 0974-598X
  • [Journal-full-title] Lung India : official organ of Indian Chest Society
  • [ISO-abbreviation] Lung India
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2988174
  • [Keywords] NOTNLM ; C-reactive protein / Chronic obstructive pulmonary disease / cytokines / interleukin-1 beta / tumor necrosis factor-α
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90. Panemangalore M, Bebe FN: Short- and long-term exposure to low levels of pesticide and flavonoid mixtures modify endogenous antioxidants in tissues of rats. J Environ Sci Health B; 2009 May;44(4):357-64
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  • Two experiments were conducted using dietary flavonoid (F) and oral pesticide (P) mixtures (FM, PM) on changes in the activities of superoxide dismutase (SOD), glutathione peroxidase (GPX) and glutathione concentrations (GSH) in male Sprague Dawley rats (150-175 g) fed for 2 or 4 weeks the AIN 93M diet with or without equal amounts of quercetin, rutin, catechin (FM) at 1.0 mM or 5 mM/kg diet, and with/without PM fed orally at 0.1 mL/d/5d/wk (PM = chlorpyrifos, endosulfan, thiram at 25% LD(50) in oil).

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  • (PMID = 19365751.001).
  • [ISSN] 1532-4109
  • [Journal-full-title] Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
  • [ISO-abbreviation] J Environ Sci Health B
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Flavonoids; 0 / Pesticides; EC 1.11.1.9 / Glutathione Peroxidase; EC 1.15.1.1 / Superoxide Dismutase; GAN16C9B8O / Glutathione
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91. Qi X, Reed JT, Wang G, Han S, Englander EW, Greeley GH Jr: Ghrelin secretion is not reduced by increased fat mass during diet-induced obesity. Am J Physiol Regul Integr Comp Physiol; 2008 Aug;295(2):R429-35
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  • Adult male Sprague-Dawley rats were fed a standard AIN-76A (approximately 5-12% of calories from fat) or an HF (approximately 45% of calories from fat) diet.

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  • (PMID = 18495830.001).
  • [ISSN] 0363-6119
  • [Journal-full-title] American journal of physiology. Regulatory, integrative and comparative physiology
  • [ISO-abbreviation] Am. J. Physiol. Regul. Integr. Comp. Physiol.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK061614; United States / NIDDK NIH HHS / DK / R01 DK-61614
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dietary Fats; 0 / Ghrelin; 06LU7C9H1V / Triiodothyronine
  • [Other-IDs] NLM/ PMC2519926
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92. Mamiya T, Kise M, Morikawa K, Aoto H, Ukai M, Noda Y: Effects of pre-germinated brown rice on depression-like behavior in mice. Pharmacol Biochem Behav; 2007 Jan;86(1):62-7
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  • We investigated the antidepressant-like effects of pre-germinated brown rice (PGBR) and polished rice (PR) pellets, respectively, in comparison with control (AIN-93G) pellets in the forced swimming test and the learned helplessness paradigm in mice.

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  • (PMID = 17258802.001).
  • [ISSN] 0091-3057
  • [Journal-full-title] Pharmacology, biochemistry, and behavior
  • [ISO-abbreviation] Pharmacol. Biochem. Behav.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Serotonin Plasma Membrane Transport Proteins; 112692-38-3 / Receptor, Serotonin, 5-HT1A; 333DO1RDJY / Serotonin; 534-82-7 / Methoxyhydroxyphenylglycol; 54-16-0 / Hydroxyindoleacetic Acid; X4W3ENH1CV / Norepinephrine
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93. Nakaya Y, Uehara M, Katsumata S, Suzuki K, Sakai K, Ohnishi R, Akiyama S, Ohta A: The frequency of magnesium consumption directly influences its serum concentration and the amount of elutable bone magnesium in rats. Magnes Res; 2010 Mar;23(1):48-56
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  • The rats were fed 0.5-fold (Mg250 group), 1-fold (Mg500 group), or 1.5-fold (Mg750 group) the amounts of recommended Mg in their standard AIN-93G diet (Mg: 478 mg/kg diet) during the recovery period (12 d).

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  • (PMID = 20228011.001).
  • [ISSN] 1952-4021
  • [Journal-full-title] Magnesium research
  • [ISO-abbreviation] Magnes Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] I38ZP9992A / Magnesium
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94. de Souza MO, Silva M, Silva ME, Oliveira Rde P, Pedrosa ML: Diet supplementation with acai (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress and the serum lipid profile in rats. Nutrition; 2010 Jul-Aug;26(7-8):804-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Female Fischer rats were fed a standard AIN-93 M diet (control) or a hypercholesterolemic diet that contained 25% soy oil and 1% cholesterol.

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20022468.001).
  • [ISSN] 1873-1244
  • [Journal-full-title] Nutrition (Burbank, Los Angeles County, Calif.)
  • [ISO-abbreviation] Nutrition
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticholesteremic Agents; 0 / Antioxidants; 0 / Biomarkers; 0 / Cholesterol, Dietary; 0 / Plant Preparations; 97C5T2UQ7J / Cholesterol; EC 1.15.1.1 / Superoxide Dismutase; EC 3.1.8.1 / Aryldialkylphosphatase
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95. Allam MF, Abd Elaziz KM: Role of members of university students' unions in tobacco prevention. J Prev Med Hyg; 2007 Dec;48(4):136-40
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  • METHODOLOGY: A random sample of members of Ain Shams University Students' Unions was subjected to an interview questionnaire.

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  • (PMID = 18557308.001).
  • [ISSN] 1121-2233
  • [Journal-full-title] Journal of preventive medicine and hygiene
  • [ISO-abbreviation] J Prev Med Hyg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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96. Zou W, Noh SK, Owen KQ, Koo SI: Dietary L-carnitine enhances the lymphatic absorption of fat and alpha-tocopherol in ovariectomized rats. J Nutr; 2005 Apr;135(4):753-6
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  • OX adult rats were weight-matched and assigned to 2 groups fed a modified AIN-93G diet containing alphaTOH-stripped soybean oil without (-CN) or with (+CN) supplemental CN at 150 mg/kg diet.

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  • (PMID = 15795429.001).
  • [ISSN] 0022-3166
  • [Journal-full-title] The Journal of nutrition
  • [ISO-abbreviation] J. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] H4N855PNZ1 / alpha-Tocopherol; S7UI8SM58A / Carnitine
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97. Holder-Murray J, Fichera A: Anal transition zone in the surgical management of ulcerative colitis. World J Gastroenterol; 2009 Feb 21;15(7):769-73
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  • [Title] Anal transition zone in the surgical management of ulcerative colitis.
  • Preservation of the anal transition zone has long been a significant source of controversy in the surgical management of ulcerative colitis.
  • The two techniques for restorative proctocolectomy and ileal pouch anal anastomosis (RPC IPAA) in common practice are a stapled anastomosis and a handsewn anastomosis; these techniques differ in the amount of remaining rectal mucosa and therefore the presence of the anal transition zone following surgery.
  • Each technique has advantages and disadvantages in long-term functional outcomes, operative and postoperative complications, and risk of neoplasia.
  • Therefore, we propose a selective approach to performing a stapled RPC IPAA based on the presence of dysplasia in the preoperative endoscopic evaluation.
  • [MeSH-major] Anal Canal / anatomy & histology. Anal Canal / surgery. Colitis, Ulcerative / surgery. Colonic Pouches. Proctocolectomy, Restorative / methods

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  • (PMID = 19230038.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Editorial
  • [Publication-country] China
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98. Bean SM, Chhieng DC, Roberson J, Raper JL, Broker TR, Hoesley CJ, Eltoum IA, Jin G: Anal-rectal cytology: correlation with human papillomavirus status and biopsy diagnoses in a population of HIV-positive patients. J Low Genit Tract Dis; 2010 Apr;14(2):90-6
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  • [Title] Anal-rectal cytology: correlation with human papillomavirus status and biopsy diagnoses in a population of HIV-positive patients.
  • OBJECTIVES: We describe the cytological distribution of disease, correlate cytological diagnoses with human papillomavirus (HPV) DNA status and surgical biopsy diagnoses, determine if CD4 counts correlate with lesion severity, and compare anal-rectal data of HIV-infected patients (primarily men) with cervical data.
  • MATERIALS AND METHODS: A retrospective search of the computerized database identified 118 HIV-positive patients who had anal-rectal cytology.
  • Cytology results were compared with available follow-up data including repeat anal-rectal cytology tests, surgical biopsy, CD4 counts, and HPV DNA polymerase chain reaction-based genotyping.
  • RESULTS: Cytological diagnoses included 3% unsatisfactory for diagnosis, 41% negative for intraepithelial lesion or malignancy (NILM), 23% atypical squamous cells of undermined significance (ASC-US), 31% low-grade squamous intraepithelial lesion (LSIL), and 2% high-grade squamous intraepithelial lesion (HSIL) (ASC-US/squamous intraepithelial lesion, 0.7:1).
  • Two anal intraepithelial neoplasia (AIN) II, 10 AIN III, and 1 invasive squamous cell carcinoma were histologically detected (11%).
  • The majority of AIN II was preceded by LSIL, 54%; ASC-US, 15%; and HSIL, 8%.
  • CONCLUSIONS: Anal-rectal cytology is a useful screening test.
  • A high percentage of AIN II lesions were detected in this at-risk population, and the majority was detected following cytological abnormality.
  • [MeSH-major] Anal Canal / pathology. HIV Infections / complications. Papillomaviridae / isolation & purification. Papillomavirus Infections / epidemiology. Rectal Neoplasms / epidemiology. Rectum / pathology

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  • (PMID = 20354415.001).
  • [ISSN] 1526-0976
  • [Journal-full-title] Journal of lower genital tract disease
  • [ISO-abbreviation] J Low Genit Tract Dis
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA83679
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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99. El-Habashy SA, Matter RM, El-Hadidi ES, Afifi HR: Plasma adrenomedullin level in Egyptian children and adolescents with type 1 diabetes mellitus: relationship to microvascular complications. Diabetol Metab Syndr; 2010;2:12
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  • METHODS: The study was performed in the Diabetes Specialized Clinic, Children's Hospital of Ain Shams University in Cairo, Egypt.

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  • (PMID = 20181139.001).
  • [ISSN] 1758-5996
  • [Journal-full-title] Diabetology & metabolic syndrome
  • [ISO-abbreviation] Diabetol Metab Syndr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2834643
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100. Newland MC, Reed MN, LeBlanc A, Donlin WD: Brain and blood mercury and selenium after chronic and developmental exposure to methylmercury. Neurotoxicology; 2006 Sep;27(5):710-20
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  • Blood and brain concentrations of these elements were determined in female rats after consuming AIN-93-based diets containing 0.06 or 0.6 ppm of selenium (Se) and drinking water containing 0, 0.5, or 5 ppm of mercury as methylmercury (MeHg) for 6 or 18 months.

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  • (PMID = 16824603.001).
  • [ISSN] 0161-813X
  • [Journal-full-title] Neurotoxicology
  • [ISO-abbreviation] Neurotoxicology
  • [Language] eng
  • [Grant] United States / NIEHS NIH HHS / ES / ES 10865
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Methylmercury Compounds; H6241UJ22B / Selenium
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