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[Title] Survival after pancreaticoduodenectomy for ampullary cancer is not affected by age.

BACKGROUND: Although pancreaticoduodenectomy (PD) provides the best chance of survival for elderly patients with ampullary carcinoma, it is associated with considerable surgical risk.

The aim of the present study was to compare the benefits and risks of pancreaticoduodenectomy as a treatment of ampullary carcinoma between young and elderly patients.

Comparison of the biological aggressiveness of ampullary cancer between old and younger patients was also performed by immunohistochemical study of several prognostic biological markers, including MUC1, MUC2, CK17, and CDX2.

RESULTS: For patients in whom ampullary carcinoma was presumed resectable preoperatively, actuarial survival was significantly poorer in 55 elderly patients because 9 of them did not have PD (the other 46 had PD) than in 101 younger patients (all had PD).

There were no significant differences in MUC1, CK17, MUC2, and CDX2 immunohistochemical staining of ampullary carcinomas between elderly and young patients.

CONCLUSIONS: Our data support the conclusion that ampullary cancers in elderly patients should be treated as aggressively as in younger patients.

[MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Pancreaticoduodenectomy / mortality

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[Cites] Ann Surg. 1998 Jun;227(6):821-31 [9637545.001]

[Cites] Arch Surg. 2001 Apr;136(4):391-8 [11296108.001]

[Cites] Surg Oncol. 2004 Dec;13(4):201-10 [15615658.001]

[Cites] Ann Surg Oncol. 2005 Dec;12(12):955-6 [16228813.001]

[Cites] World J Surg. 2006 Nov;30(11):1992-2001; discussion 2002-3 [16957825.001]

[Cites] Ann Surg. 1995 Oct;222(4):426-34; discussion 434-7 [7574924.001]

[Cites] Br J Cancer. 1997;75(4):593-6 [9052416.001]

[Cites] Am J Surg. 2000 Jul;180(1):13-7 [11036132.001]

[Cites] Am J Surg. 1991 Dec;162(6):532-5; discussion 535-6 [1670220.001]

[Cites] Ann Surg Oncol. 2005 Dec;12(12):971-80 [16244798.001]

[Cites] Surgery. 2000 Jun;127(6):628-33 [10840357.001]

[Cites] Br J Surg. 1998 May;85(5):607-10 [9635804.001]

[Cites] Arch Surg. 2003 Oct;138(10):1061-7 [14557121.001]

[Cites] Eur J Surg Oncol. 2001 Sep;27(6):549-57 [11520088.001]

[Cites] Am J Surg Pathol. 2005 Mar;29(3):359-67 [15725805.001]

[Cites] Ann Surg. 2005 Jul;242(1):92-100 [15973106.001]

[Cites] Ann Surg. 1993 May;217(5):430-5; discussion 435-8 [8098202.001]

[Cites] J Clin Oncol. 2005 Mar 20;23(9):1811-8 [15774774.001]

(PMID = 20714897.001).

[ISSN] 1432-2323

[Journal-full-title] World journal of surgery

[ISO-abbreviation] World J Surg

[Language] eng

[Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

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Whipple procedure is the most complex abdominal surgical procedure to treat periampullary carcinoma.

The patient was a 40-year-old, Thai-Muslim female, with the diagnosis of ampullary carcinoma.

[MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Laparoscopy / methods. Pancreaticoduodenectomy / methods

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(PMID = 20873085.001).

[ISSN] 0125-2208

[Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet

[ISO-abbreviation] J Med Assoc Thai

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Thailand

   

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The three cases were diagnosed to have bile duct cancer, intraductal papillary mucinous neoplasm, and carcinoma of the ampulla of Vater, respectively.

[MeSH-minor] Aged. Ampulla of Vater. Carcinoma, Pancreatic Ductal / epidemiology. Carcinoma, Pancreatic Ductal / surgery. Common Bile Duct Neoplasms / epidemiology. Common Bile Duct Neoplasms / surgery. Comorbidity. Humans. Kidney Failure, Chronic / epidemiology. Kidney Failure, Chronic / therapy. Length of Stay. Male. Middle Aged

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[Cites] Ann Surg. 2006 Jul;244(1):10-5 [16794383.001]

[Cites] World J Surg. 2005 Nov;29(11):1409-14 [16222456.001]

[Cites] Am J Surg. 2004 Feb;187(2):201-8 [14769305.001]

[Cites] Hepatogastroenterology. 1993 Jun;40(3):249-52 [8392024.001]

[Cites] Am J Kidney Dis. 1991 Sep;18(3):326-35 [1882824.001]

[Cites] Ann Surg. 1935 Oct;102(4):763-79 [17856666.001]

[Cites] J Am Coll Surg. 2003 Aug;197(2):223-31; discussion 231-2 [12892800.001]

[Cites] World J Surg. 1999 Feb;23(2):164-71; discussion 171-2 [9880426.001]

[Cites] J Surg Oncol. 2001 Dec;78(4):241-6; discussion 246-7 [11745817.001]

[Cites] Surg Today. 2005;35(5):345-50 [15864414.001]

(PMID = 19039646.001).

[ISSN] 0941-1291

[Journal-full-title] Surgery today

[ISO-abbreviation] Surg. Today

[Language] eng

[Publication-type] Journal Article

[Publication-country] Japan

   

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[Title] Increased integrity of free circulating DNA in sera of patients with colorectal or periampullary cancer: direct quantitative PCR for ALU repeats.

BACKGROUND: Cell-free DNA circulating in blood is a candidate biomarker for malignant tumors.

Unlike uniformly truncated DNA released from apoptotic nondiseased cells, DNA released from dead cancer cells varies in size.

We developed a novel method to measure the ratio of longer to shorter DNA fragments (DNA integrity) in serum as a potential biomarker for patients with colorectal cancer (CRC) or periampullary cancers (PACs).

[MeSH-major] Ampulla of Vater. Biomarkers, Tumor / blood. Carcinoma, Pancreatic Ductal / diagnosis. Colorectal Neoplasms / diagnosis. Common Bile Duct Neoplasms / diagnosis. DNA / blood. Duodenal Neoplasms / diagnosis. Pancreatic Neoplasms / diagnosis

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(PMID = 16723681.001).

[ISSN] 0009-9147

[Journal-full-title] Clinical chemistry

[ISO-abbreviation] Clin. Chem.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor; 9007-49-2 / DNA

   

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[Title] A Case of Metastatic Renal Cell Cancer Presenting as Jaundice.

Renal cell carcinoma is the second most common urological malignancy and it runs a highly variable clinical course.

We describe a case of metastatic renal cell carcinoma in a 50-year-old lady with metastasis to the ampulla of Vater, clinically masquerading as cholelithiasis and biliary colic.

Ampullary metastases are rare, and prompt recognition and intervention are necessary before patient's performance status is compromised.

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[Cites] BMC Gastroenterol. 2007 Jan 31;7:4 [17266757.001]

[Cites] Semin Oncol. 2006 Oct;33(5):527-33 [17045081.001]

[Cites] Dig Dis Sci. 1991 Mar;36(3):376-8 [1995276.001]

[Cites] Clin Cancer Res. 2004 Sep 15;10(18 Pt 2):6335S-41S [15448027.001]

[Cites] Urol Oncol. 2009 Mar-Apr;27(2):149-54 [18439851.001]

[Cites] Can J Gastroenterol. 1998 Jan-Feb;12(1):75-8 [9544417.001]

[Cites] Am J Gastroenterol. 1993 Feb;88(2):300-2 [8424439.001]

[Cites] Am J Gastroenterol. 1989 Jan;84(1):81-3 [2912036.001]

[Cites] J Gastrointest Surg. 2008 Aug;12 (8):1465-8 [18066632.001]

[Cites] Surgery. 1996 Mar;119(3):349-51 [8619191.001]

(PMID = 29147211.001).

[ISSN] 1920-454X

[Journal-full-title] World journal of oncology

[ISO-abbreviation] World J Oncol

[Language] eng

[Publication-type] Journal Article

[Publication-country] Canada

[Keywords] NOTNLM ; Complication / Kidney cancer / Metastasis

   

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[Title] Our local experience with the surgical treatment of ampullary cancer.

BACKGROUND: The aim of this study is to report the outcome after surgical treatment of 32 patients with ampullary cancers from 1990 to 1999.

METHODS: Twenty-one of them underwent pancreaticoduodenectomy and 9 local excision of the ampullary lesion.

RESULTS: When the final histological diagnosis was compared with the preoperative histological finding on biopsy, accurate diagnosis was preoperatively established in 24 patients.

Following local excision of the ampullary cancer, the survival rate at 3 and 5 years was 77.7% and 33.3% respectively.

CONCLUSION: In this series, local resection was a safe option in patients with significant co-morbidity or small ampullary tumors less than 2 cm in size, and was associated with satisfactory long-term survival rates.

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[Cites] Br J Surg. 1995 Dec;82(12):1693-6 [8548244.001]

[Cites] Cancer. 2002 Oct 15;95(8):1685-95 [12365016.001]

[Cites] Hepatogastroenterology. 1999 May-Jun;46(27):1973-9 [10430380.001]

[Cites] Arch Surg. 1999 May;134(5):526-32 [10323425.001]

[Cites] Ann Surg. 1990 Apr;211(4):447-58 [2322039.001]

[Cites] Am J Surg. 1989 Dec;158(6):593-6; discussion 596-7 [2589595.001]

[Cites] Br J Surg. 1987 Oct;74(10):957-61 [3664230.001]

[Cites] Surgery. 1995 Mar;117(3):247-53 [7878528.001]

[Cites] Br J Surg. 1994 May;81(5):668-71 [7913860.001]

[Cites] Ann Surg. 1993 Apr;217(4):356-68 [7682052.001]

[Cites] Arch Surg. 1994 Oct;129(10):1075-80 [7944938.001]

[Cites] Surg Gynecol Obstet. 1993 Jan;176(1):33-8 [8093983.001]

[Cites] Chirurg. 1993 Jun;64(6):476-82 [8359060.001]

[Cites] Leber Magen Darm. 1993 Jan;23(1):13-8, 21-3 [8445972.001]

[Cites] Surgery. 2000 Jun;127(6):628-33 [10840357.001]

[Cites] Ann Surg. 1996 Feb;223(2):134-40 [8597506.001]

[Cites] Arch Surg. 1996 Apr;131(4):366-71 [8615720.001]

[Cites] Eur J Surg Oncol. 1996 Aug;22(4):366-71 [8783654.001]

[Cites] World J Surg. 1997 May;21(4):379-83 [9143568.001]

[Cites] Ann Surg. 1998 Jun;227(6):821-31 [9637545.001]

[Cites] Surgery. 1986 Oct;100(4):716-23 [3764694.001]

[Cites] Acta Chir Scand. 1986 Aug-Sep;152:537-9 [3788399.001]

[Cites] Cancer. 1987 Feb 1;59(3):506-15 [3791159.001]

[Cites] Br J Surg. 1987 Feb;74(2):116-8 [3815026.001]

[Cites] Br J Surg. 1986 Jan;73(1):72-3 [3947884.001]

[Cites] Am J Surg. 1985 Jan;149(1):46-52 [3966641.001]

[Cites] J R Coll Surg Edinb. 1982 May;27(3):154-7 [7108832.001]

[Cites] Endoscopy. 1981 Jul;13(4):154-6 [7250083.001]

(PMID = 16131399.001).

[ISSN] 1477-7800

[Journal-full-title] International seminars in surgical oncology : ISSO

[ISO-abbreviation] Int Semin Surg Oncol

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Other-IDs] NLM/ PMC1215507

   

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[Title] Duodenal cancer arising from the remaining duodenum after pylorus-preserving pancreatoduodenectomy for ampullary cancer in familial adenomatous polyposis.

We herein report a rare occurrence of duodenal cancer arising from the remaining duodenum after pylorus-preserving pancreatoduodenectomy for ampullary cancer in familial adenomatous polyposis (FAP).

During the current admission, the patient was diagnosed with adenocarcinoma in the Vater's ampulla using imaging and pathological examinations.

[MeSH-minor] Adult. Ampulla of Vater / pathology. Cholangiopancreatography, Endoscopic Retrograde / methods. Duodenoscopy / methods. Female. Follow-Up Studies. Humans. Neoplasm, Residual / pathology. Neoplasm, Residual / surgery. Pylorus. Risk Assessment. Treatment Outcome

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[Cites] Ann Surg. 1993 Feb;217(2):101-8 [8382467.001]

[Cites] Dis Colon Rectum. 1990 Aug;33(8):639-42 [2165452.001]

[Cites] Lancet. 1995 Apr 1;345(8953):855-6 [7898240.001]

[Cites] J R Soc Med. 1991 Aug;84(8):476-8 [1653358.001]

[Cites] Lancet. 1988 May 21;1(8595):1149-51 [2896968.001]

[Cites] Int J Colorectal Dis. 1998;13(1):39-42 [9548099.001]

[Cites] J Clin Pathol. 1994 Aug;47(8):709-10 [7962621.001]

[Cites] Br J Surg. 1998 May;85(5):665-8 [9635818.001]

[Cites] J Gastrointest Surg. 2000 Jan-Feb;4(1):13-21, discussion 22-3 [10631358.001]

[Cites] Lancet. 1989 Sep 30;2(8666):783-5 [2571019.001]

[Cites] Gut. 1997 Jun;40(6):716-9 [9245923.001]

[Cites] J Gastrointest Surg. 2002 Sep-Oct;6(5):671-5 [12399055.001]

[Cites] Ann Surg. 1993 May;217(5):430-5; discussion 435-8 [8098202.001]

(PMID = 15749602.001).

[ISSN] 1091-255X

[Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

[ISO-abbreviation] J. Gastrointest. Surg.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

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[Title] A case of early depressed-type ampullary carcinoma treated by wire-guided endoscopic resection.

A 72-year-old man, with known prostate cancer, was admitted to our endoscopic unit for further evaluation of an obstruction at major papilla level.

Endoscopic cholangiopancreatography revealed a depressed-type carcinoma at the ampulla of Vater and dilation of both the common bile and pancreatic ducts without intraductal filling defects.

Intraductal ultrasonography showed a hypoechoic mass limited to the ampulla of Vater.

Histologic examination of the resected specimen showed a completely excised well-differentiated adenocarcinoma limited to the ampulla of Vater.

Both accurate preoperative staging and proper histologic evaluation of the resected specimen seem to justify endoscopic treatment of early ampullary cancer by an experienced endoscopist.

[MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Sphincterotomy, Endoscopic / methods

[MeSH-minor] Aged. Cholangiopancreatography, Endoscopic Retrograde. Endosonography. Humans. Male. Neoplasm Staging. Treatment Outcome

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(PMID = 18097317.001).

[ISSN] 1530-4515

[Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques

[ISO-abbreviation] Surg Laparosc Endosc Percutan Tech

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

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[Title] Primary Pure Squamous Cell Carcinoma of the Duodenum: A Case Report.

: Only two cases of squamous cell carcinoma of the duodenum have been reported in the literature.

The author herein reports a case of squamous cell carcinoma of the duodenum.

The tumor was circumferential elevated one with duodenal obstruction, and located in the descending part near and distal to the ampulla of Vater.

The duodenal tumor was different from ampullary tumor and pancreatic tumor.

All the six biopsies showed malignant cells arranged in a medullary pattern.

The malignant cells showed hyperchromatic nuclei, and mitotic figures were scattered.

The pathologic features were interpreted as a squamous cell carcinoma of the duodenum.

The carcinoma was pure squamous cell carcinoma without differentiation into adenocarcinoma or endocrine carcinoma.

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(PMID = 27956983.001).

[ISSN] 1918-2805

[Journal-full-title] Gastroenterology research

[ISO-abbreviation] Gastroenterology Res

[Language] eng

[Publication-type] Journal Article

[Publication-country] Canada

[Keywords] NOTNLM ; Duodenum / Histopathology / Squamous cell carcinoma

   

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[Title] Associations between small intestine cancer and other primary cancers: an international population-based study.

Cancer of the small intestine is a rare neoplasm, and its etiology remains poorly understood.

Analysis of other primary cancers in individuals with small intestine cancer may help elucidate the causes of this neoplasm and the underlying mechanisms.

We included 10,946 cases of first primary small intestine cancer from 13 cancer registries in a pooled analysis.

The observed numbers of 44 types of second primary cancer were compared to the expected numbers derived from the age-, gender- and calendar period-specific cancer incidence rates in each registry.

We also calculated the standardized incidence ratios (SIR) for small intestine cancer as a second primary after other cancers.

There was a 68% overall increase in the risk of a new primary cancer after small intestine carcinoma (SIR = 1.68, 95% confidence interval [CI] = 1.47-1.71), that remained constant over time.

Significant (p < 0.05) increases were observed for cancers of the oropharynx, colon, rectum, ampulla of Vater, pancreas, corpus uteri, ovary, prostate, kidney, thyroid gland, skin and soft tissue sarcomas.

Small intestine cancer as a second primary was increased significantly after all these cancers, except after oropharyngeal and kidney cancers.

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[Copyright] Copyright 2005 Wiley-Liss, Inc.

(PMID = 16003748.001).

[ISSN] 0020-7136

[Journal-full-title] International journal of cancer

[ISO-abbreviation] Int. J. Cancer

[Language] eng

[Grant] United States / NCI NIH HHS / CA / R03 CA101442-02

[Publication-type] Journal Article; Multicenter Study; Research Support, N.I.H., Extramural

[Publication-country] United States

   

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However, locoregional extension of these tumors is usually advanced with intrahepatic and lymph-node metastases at the time of diagnosis.

Only a small number of ICC cases, accompanied with ECC, gall bladder carcinoma, and ampullary carcinoma, have been reported in the studies of chemotherapy due to the rarity of the disease.

However, in some reports, significant anti-cancer effects were achieved with a response rate of up to 40% and a median survival of one year.

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(PMID = 21160974.001).

[ISSN] 1948-5182

[Journal-full-title] World journal of hepatology

[ISO-abbreviation] World J Hepatol

[Language] eng

[Publication-type] Journal Article

[Publication-country] China

[Other-IDs] NLM/ PMC2998957

[Keywords] NOTNLM ; Chemotherapy / Intrahepatic cholangiocarcinoma / Surgery

   

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[Title] Large-cell neuroendocrine carcinoma of the ampulla of Vater.

Large-cell neuroendocrine carcinoma is a high-grade neuroendocrine carcinoma, originally described in the lung.

The tumor rarely occurs in extrapulmonary sites like the gastrointestinal tract, and only few examples have been described in the ampulla of Vater.

A new case of large-cell neuroendocrine carcinoma of the ampulla of Vater in a 60-year-old man is reported.

After pancreatoduodenectomy, macroscopic examination revealed ulcerated tumor in the region of the ampulla of Vater.

Two months after surgery, liver metastases occurred, confirming highly aggressive behavior of large-cell neuroendocrine carcinoma.

[MeSH-major] Ampulla of Vater / pathology. Carcinoma, Large Cell / pathology. Carcinoma, Neuroendocrine / pathology. Common Bile Duct Neoplasms / pathology. Liver Neoplasms / secondary

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[Cites] J Surg Res. 2008 Jul;148(1):31-7 [18570928.001]

[Cites] Virchows Arch. 2007 Aug;451 Suppl 1:S9-27 [17684761.001]

[Cites] Am J Surg Pathol. 2006 Aug;30(8):945-53 [16861964.001]

[Cites] Oncogene. 2004 Sep 2;23(40):6693-701 [15235588.001]

[Cites] Acta Pathol Jpn. 1992 Jul;42(7):529-35 [1384272.001]

[Cites] Nat Rev Cancer. 2006 Jan;6(1):38-51 [16397526.001]

[Cites] Am J Surg Pathol. 2005 May;29(5):588-94 [15832081.001]

[Cites] Endocr Relat Cancer. 2006 Dec;13(4):1237-50 [17158768.001]

[Cites] Am J Surg Pathol. 2008 May;32(5):719-31 [18360283.001]

[Cites] Int J Dermatol. 2008 May;47(5):496-501 [18412870.001]

[Cites] Hepatobiliary Pancreat Dis Int. 2006 Aug;5(3):465-7 [16911952.001]

[Cites] Surg Today. 2006;36(11):1032-5 [17072731.001]

[Cites] Surgery. 1994 Jun;115(6):762-6 [8197570.001]

[Cites] Dis Colon Rectum. 2004 Feb;47(2):163-9 [15043285.001]

[Cites] J Surg Oncol. 2007 Feb 1;95(2):110-7 [17066436.001]

[Cites] J Chin Med Assoc. 2008 Oct;71(10):536-40 [18955190.001]

[Cites] J Clin Pathol. 2004 Oct;57(10):1098-100 [15452169.001]

[Cites] ANZ J Surg. 2002 Jul;72(7):531-3 [12123522.001]

[Cites] Arch Pathol Lab Med. 2003 Feb;127(2):221-3 [12562240.001]

[Cites] Arch Pathol Lab Med. 1998 Nov;122(11):1010-7 [9822131.001]

[Cites] Am J Surg Pathol. 1991 Jun;15(6):529-53 [1709558.001]

[Cites] Gastrointest Endosc. 2000 May;51(5):593 [10805848.001]

[Cites] Pathol Int. 2005 Aug;55(8):524-9 [15998383.001]

[Cites] Gastrointest Endosc. 2004 Nov;60(5):838-41 [15557973.001]

(PMID = 19898974.001).

[ISSN] 1559-131X

[Journal-full-title] Medical oncology (Northwood, London, England)

[ISO-abbreviation] Med. Oncol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor

   

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[Title] Biliary strictures secondary to tuberculosis and early ampullary carcinoma.

Malignancies are important causes and are often unresectable at the time of diagnosis.

We report a 67-year-old man with unexpected findings of obstructive jaundice secondary to biliary TB and an early ampullary tumour.

[MeSH-minor] Aged. Ampulla of Vater / pathology. Biliary Tract Surgical Procedures. Constriction, Pathologic / pathology. Humans. Male. Risk Factors

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(PMID = 19352560.001).

[ISSN] 0037-5675

[Journal-full-title] Singapore medical journal

[ISO-abbreviation] Singapore Med J

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Singapore

   

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Between July 1994 and December 2004, 222 PD (78% pylorus preserving, 19% Whipple, and 3% total pancreatectomy) were performed for malignant disease.

Long-term survival was analyzed in 165 patients with pancreatic (n = 110), ampullary (n = 33), or distal bile (n = 22) duct cancer using univariate (log-rank) and multivariate (Cox regression) methods.

Five-year survival rates were 15% in cancer of the pancreatic head, 22% in ampullary cancer, and 24% in distal bile duct cancer (P = 0.02).

Univariate survival analysis of the 110 patients with cancer of the pancreatic head revealed that a histologically undifferentiated tumor (P = 0.05) and positive resection margins (P = 0.02) were associated with a poorer survival.

In case of tumor adherence or infiltration, combined resection of the pancreatic head and the vein should always be considered in the absence of other contraindications for resection.

[MeSH-major] Mesenteric Veins / pathology. Mesenteric Veins / surgery. Pancreatic Neoplasms. Pancreaticoduodenectomy / methods. Portal Vein / pathology. Portal Vein / surgery. Vascular Surgical Procedures / methods

[MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Male. Middle Aged. Morbidity / trends. Neoplasm Invasiveness. Postoperative Period. Prospective Studies. Survival Rate. Time Factors. Treatment Outcome

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[Cites] J Gastrointest Surg. 2005 Nov;9(8):1080-6; discussion 1086-7 [16269378.001]

[Cites] Am J Surg. 2001 Aug;182(2):120-9 [11574081.001]

[Cites] J Vasc Interv Radiol. 2002 Aug;13(8):805-14 [12171984.001]

[Cites] Ann Surg. 1998 Oct;228(4):508-17 [9790340.001]

[Cites] Pancreas. 2004 Apr;28(3):289-92 [15084973.001]

[Cites] Surgery. 1995 Jan;117(1):50-5 [7809836.001]

[Cites] J Gastrointest Surg. 2004 Dec;8(8):935-49; discussion 949-50 [15585381.001]

[Cites] Chirurg. 2000 Jul;71(7):803-7 [10986602.001]

[Cites] Surgery. 2001 Feb;129(2):158-63 [11174708.001]

[Cites] J Gastrointest Surg. 2003 Dec;7(8):1089-95 [14675720.001]

[Cites] J Gastrointest Surg. 2005 Dec;9(9):1191-204; discussion 1204-6 [16332474.001]

[Cites] Ann Surg. 1984 Apr;199(4):418-25 [6712317.001]

[Cites] Pancreas. 2004 Apr;28(3):219-30 [15084961.001]

[Cites] World J Surg. 1999 Sep;23(9):926-9 [10449822.001]

[Cites] Am J Surg. 1996 Jan;171(1):170-4; discussion 174-5 [8554135.001]

[Cites] Am J Surg. 2004 Feb;187(2):201-8 [14769305.001]

[Cites] Br J Surg. 2004 May;91(5):586-94 [15122610.001]

[Cites] Am J Surg. 2003 May;185(5):476-80 [12727570.001]

[Cites] J Gastrointest Surg. 2000 Nov-Dec;4(6):567-79 [11307091.001]

[Cites] Surgery. 1973 Feb;73(2):307-20 [4265314.001]

[Cites] Ann Surg. 2004 Aug;240(2):293-8 [15273554.001]

[Cites] Ann Surg. 2000 Dec;232(6):786-95 [11088073.001]

[Cites] Br J Surg. 1998 May;85(5):611-7 [9635805.001]

[Cites] J Am Coll Surg. 1999 Jul;189(1):1-7 [10401733.001]

[Cites] Ann Surg. 1996 Feb;223(2):154-62 [8597509.001]

[Cites] Eur J Surg Oncol. 2001 Sep;27(6):549-57 [11520088.001]

[Cites] Arch Surg. 1989 Jan;124(1):127-32 [2910241.001]

[Cites] N Engl J Med. 2004 Mar 18;350(12):1200-10 [15028824.001]

[Cites] Br J Surg. 1994 Aug;81(8):1190-3 [7953357.001]

[Cites] Surgery. 1991 Apr;109(4):481-7 [1848949.001]

[Cites] Ann Surg. 1995 Dec;222(6):711-8 [8526577.001]

[Cites] World J Surg. 2001 Aug;25(8):1002-5 [11571964.001]

[Cites] J Gastrointest Surg. 2003 Feb;7(2):209-19 [12600445.001]

[Cites] Ann Surg. 1996 Sep;224(3):342-7; discussion 347-9 [8813262.001]

(PMID = 16966029.001).

[ISSN] 1091-255X

[Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

[ISO-abbreviation] J. Gastrointest. Surg.

[Language] eng

[Publication-type] Journal Article; Multicenter Study

[Publication-country] United States

   

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[Title] Guidelines for the management of biliary tract and ampullary carcinomas: surgical treatment.

The only curative treatment in biliary tract cancer is surgical treatment.

Although hepatectomy and/or pancreaticoduodenectomy are preferable for the curative resection of bile duct cancer, extrahepatic bile duct resection alone is also considered in patients for whom it is judged that curative resection would be achieved after a strict diagnosis of its local extension.

Prognostic factors after resection for bile duct cancer include positive surgical margins, especially in the ductal stump; lymph node metastasis; perineural invasion; and combined vascular resection due to portal vein and/or hepatic artery invasion.

For patients with suspected gallbladder cancer, laparoscopic cholecystectomy is not recommended, and open cholecystectomy should be performed as a rule.

When gallbladder cancer invading the subserosal layer or deeper has been detected after simple cholecystectomy, additional resection should be considered.

Prognostic factors after resection for gallbladder cancer include the depth of mural invasion; lymph node metastasis; extramural extension, especially into the hepatoduodenal ligament; perineural invasion; and the degree of curability.

Pancreaticoduodenectomy is indicated for ampullary carcinoma, and limited operation is also indicated for carcinoma in adenoma.

The prognostic factors after resection for ampullary carcinoma include lymph node metastasis, pancreatic invasion, and perineural invasion.

[MeSH-major] Ampulla of Vater / surgery. Biliary Tract Neoplasms / surgery. Carcinoma / surgery

[MeSH-minor] Biliary Tract / pathology. Biliary Tract Surgical Procedures / methods. Evidence-Based Medicine / methods. Humans. Neoplasm Staging. Preoperative Care / methods. Survival Rate

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[Cites] Ann Surg. 2003 Nov;238(5):720-7 [14578735.001]

[Cites] Br J Surg. 2004 Feb;91(2):248-51 [14760676.001]

[Cites] World J Surg. 2004 Feb;28(2):160-5 [14708053.001]

[Cites] Hepatogastroenterology. 2004 May-Jun;51(57):672-4 [15143890.001]

[Cites] Ann Surg. 2004 Jul;240(1):95-101 [15213624.001]

[Cites] J Hepatobiliary Pancreat Surg. 2004;11(4):232-8 [15368106.001]

[Cites] J Hepatobiliary Pancreat Surg. 2004;11(4):239-44 [15368107.001]

[Cites] Surg Gynecol Obstet. 1986 Feb;162(2):153-8 [3945893.001]

[Cites] Br J Surg. 1986 Jan;73(1):72-3 [3947884.001]

[Cites] Cancer. 1987 Feb 1;59(3):506-15 [3791159.001]

[Cites] Am J Gastroenterol. 1987 Nov;82(11):1169-71 [3673996.001]

[Cites] Surgery. 1990 May;107(5):521-7 [2333592.001]

[Cites] Am Surg. 1990 Apr;56(4):214-7 [2194412.001]

[Cites] World J Surg. 1990 Jul-Aug;14(4):535-43; discussion 544 [2166381.001]

[Cites] Surgery. 1990 Sep;108(3):572-80 [2204130.001]

[Cites] Ann Surg. 1992 Jan;215(1):31-8 [1309988.001]

[Cites] Ann Surg. 1992 Apr;215(4):326-31 [1558412.001]

[Cites] Ann Surg. 1992 Apr;215(4):344-9 [1558415.001]

[Cites] World J Surg. 1993 Mar-Apr;17(2):250-5 [8511922.001]

[Cites] Cancer. 2005 Mar 15;103(6):1210-6 [15685618.001]

[Cites] Surgery. 2005 Apr;137(4):396-402 [15800484.001]

[Cites] Ann Surg. 2005 May;241(5):693-9; discussion 699-702 [15849505.001]

[Cites] J Gastroenterol. 2005 Jul;40(7):739-43 [16082591.001]

[Cites] Ann Surg. 2006 Jan;243(1):28-32 [16371733.001]

[Cites] J Am Coll Surg. 2006 Jan;202(1):87-92 [16377501.001]

[Cites] Br J Surg. 2006 Feb;93(2):221-5 [16363020.001]

[Cites] J Gastrointest Surg. 2006 Feb;10(2):186-92 [16455449.001]

[Cites] Ann Surg. 2006 Mar;243(3):364-72 [16495702.001]

[Cites] Ann Surg. 2006 Jul;244(1):99-105 [16794394.001]

[Cites] Ann Surg. 2006 Aug;244(2):240-7 [16858186.001]

[Cites] Am Surg. 2006 Jul;72(7):599-604; discussion 604-5 [16875081.001]

[Cites] Surgery. 2007 May;141(5):581-8 [17462457.001]

[Cites] J Hepatobiliary Pancreat Surg. 2007;14(4):345-50 [17653631.001]

[Cites] J Hepatobiliary Pancreat Surg. 2007;14(4):351-7 [17653632.001]

[Cites] Ann Surg. 2007 Dec;246(6):1052-7 [18043110.001]

[Cites] J Hepatobiliary Pancreat Surg. 2008;15(1):2-6 [18274838.001]

[Cites] Ann Surg. 1999 Nov;230(5):663-71 [10561090.001]

[Cites] J Am Coll Surg. 1999 Dec;189(6):575-83 [10589594.001]

[Cites] Am J Surg. 1995 Jun;169(6):589-94 [7771622.001]

[Cites] Surgery. 1995 Jun;117(6):616-23 [7778025.001]

[Cites] World J Surg. 1995 Sep-Oct;19(5):758-63 [7571677.001]

[Cites] Ann Surg. 1995 Nov;222(5):632-7 [7487210.001]

[Cites] J Am Coll Surg. 1995 Dec;181(6):504-10 [7582223.001]

[Cites] Am J Surg. 1996 Jan;171(1):170-4; discussion 174-5 [8554135.001]

[Cites] Ann Surg. 1996 Jan;223(1):77-83 [8554422.001]

[Cites] Ann Surg. 1996 Apr;223(4):384-94 [8633917.001]

[Cites] Surgery. 1996 May;119(5):498-504 [8619203.001]

[Cites] Br J Surg. 1996 Apr;83(4):478-81 [8665234.001]

[Cites] Ann Surg. 1999 Dec;230(6):808-18; discussion 819 [10615936.001]

[Cites] Ann Surg Oncol. 2000 Jan-Feb;7(1):55-66 [10674450.001]

[Cites] Br J Surg. 2000 Apr;87(4):418-22 [10759735.001]

[Cites] J Hepatobiliary Pancreat Surg. 2000;7(2):122-7 [10982603.001]

[Cites] J Hepatobiliary Pancreat Surg. 2000;7(2):135-41 [10982605.001]

[Cites] J Hepatobiliary Pancreat Surg. 2000;7(2):155-62 [10982608.001]

[Cites] Langenbecks Arch Surg. 2000 Dec;385(8):509-14 [11201006.001]

[Cites] J Am Coll Surg. 2001 Feb;192(2):189-95 [11220719.001]

[Cites] Ann Surg. 2001 Mar;233(3):385-92 [11224627.001]

[Cites] J Am Coll Surg. 2001 May;192(5):600-7 [11333097.001]

[Cites] Br J Surg. 2001 May;88(5):675-8 [11350438.001]

[Cites] Langenbecks Arch Surg. 2001 Mar;386(2):110-7 [11374043.001]

[Cites] Surg Laparosc Endosc Percutan Tech. 2001 Jun;11(3):176-81 [11444747.001]

[Cites] Ann Surg. 2001 Oct;234(4):507-17; discussion 517-9 [11573044.001]

[Cites] Br J Surg. 2002 Feb;89(2):179-84 [11856130.001]

[Cites] Eur J Surg Oncol. 2002 Feb;28(1):4-10 [11869005.001]

[Cites] Ann Surg. 2002 Mar;235(3):392-9 [11882761.001]

[Cites] J Hepatobiliary Pancreat Surg. 2001;8(6):511-7 [11956901.001]

[Cites] J Hepatobiliary Pancreat Surg. 2001;8(6):525-9 [11956903.001]

[Cites] Surgery. 1994 Apr;115(4):445-51 [8165536.001]

[Cites] Hepatology. 1995 Feb;21(2):434-9 [7843717.001]

[Cites] Surgery. 1995 Apr;117(4):429-34 [7716725.001]

[Cites] Eur J Surg Oncol. 1996 Aug;22(4):366-71 [8783654.001]

[Cites] Arch Surg. 1996 Sep;131(9):981-4; discussion 985 [8790169.001]

[Cites] Eur Surg Res. 1996;28(5):333-40 [8880122.001]

[Cites] Surgery. 1996 Nov;120(5):816-21 [8909516.001]

[Cites] Ann Surg. 1996 Nov;224(5):621-7 [8916877.001]

[Cites] Ann Surg. 1996 Nov;224(5):628-38 [8916878.001]

[Cites] Ann Surg. 1996 Nov;224(5):639-46 [8916879.001]

[Cites] Surg Oncol Clin N Am. 1996 Apr;5(2):317-36 [9019354.001]

[Cites] Cancer. 1997 Jan 1;79(1):26-34 [8988723.001]

[Cites] Cancer. 1997 Mar 1;79(5):892-9 [9041150.001]

[Cites] Surgery. 1997 Jun;121(6):611-7 [9186460.001]

[Cites] Br J Surg. 1997 Jul;84(7):1012-6 [9240155.001]

[Cites] Cancer. 1997 Aug 15;80(4):661-7 [9264348.001]

[Cites] Surg Today. 1997;27(8):710-3 [9306584.001]

[Cites] Hepatology. 1997 Nov;26(5):1176-81 [9362359.001]

[Cites] Cancer. 1997 Nov 15;80(10):1904-9 [9366291.001]

[Cites] Am J Clin Pathol. 1998 Jan;109(1):62-8 [9426519.001]

[Cites] Surgery. 1998 Feb;123(2):131-6 [9481397.001]

[Cites] Surgery. 1998 Nov;124(5):831-8 [9823395.001]

[Cites] Ann Surg. 1999 Jan;229(1):76-83 [9923803.001]

[Cites] Eur J Surg. 1999 Mar;165(3):215-22 [10231654.001]

[Cites] Arch Surg. 1999 May;134(5):526-32 [10323425.001]

[Cites] Semin Surg Oncol. 1999 Jun;16(4):327-31 [10332779.001]

[Cites] Hepatogastroenterology. 1999 May-Jun;46(27):1547-51 [10430292.001]

[Cites] World J Surg. 1999 Oct;23(10):989-95; discussion 996-7 [10512937.001]

[Cites] Surgery. 2004 Nov;136(5):1012-7; discussion 1018 [15523394.001]

[Cites] Ann Surg. 2005 Jan;241(1):77-84 [15621994.001]

[Cites] Radiology. 2005 Feb;234(2):625-30 [15591428.001]

[Cites] J Vasc Interv Radiol. 2005 Feb;16(2 Pt 1):215-25 [15713922.001]

[Cites] J Gastrointest Surg. 2002 Jan-Feb;6(1):50-6; discussion 56-7 [11986018.001]

[Cites] J Hepatobiliary Pancreat Surg. 2002;9(2):256-60 [12140616.001]

[Cites] Br J Surg. 2002 Sep;89(9):1130-6 [12190678.001]

[Cites] J Vasc Interv Radiol. 2002 Dec;13(12):1233-7 [12471187.001]

[Cites] J Hepatobiliary Pancreat Surg. 2002;9(5):569-75 [12541042.001]

[Cites] Ann Surg. 2003 Feb;237(2):208-17 [12560779.001]

[Cites] World J Surg. 2003 Mar;27(3):272-7 [12607050.001]

[Cites] Ann Surg Oncol. 2003 May;10(4):447-54 [12734095.001]

[Cites] Br J Surg. 2003 Jun;90(6):694-7 [12808616.001]

[Cites] Ann Surg. 2003 Jul;238(1):73-83 [12832968.001]

[Cites] Ann Surg. 2003 Jul;238(1):84-92 [12832969.001]

[Cites] Arch Surg. 2003 Jul;138(7):741-50; discussion 750 [12860755.001]

[Cites] Surg Today. 2003;33(10):740-2 [14513320.001]

(PMID = 18274843.001).

[ISSN] 0944-1166

[Journal-full-title] Journal of hepato-biliary-pancreatic surgery

[ISO-abbreviation] J Hepatobiliary Pancreat Surg

[Language] eng

[Publication-type] Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't

[Publication-country] Japan

[Other-IDs] NLM/ PMC2794356

[Investigator] Kai M; Kimura Y; Sawada S; Shimizu H; Nakagawara H; Nakachi K; Yoshitome H; Saisyo H; Ryu M; Shikata S; Nimura Y

   

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METHODS: From May 2008 to October 2008, 15 patients were performed with BPG, included pancreatic head cancer in 7 cases, duodenal adenocarcinoma in 2 cases,mass-type chronic pancreatitis with pancreatolithiasis in 1 case, ampullary carcinoma in 1 case, gallbladder cancer in 1 case, islet cell tumor in 1 case and cholangiocarcinoma in 2 cases.

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(PMID = 19563012.001).

[ISSN] 0529-5815

[Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]

[ISO-abbreviation] Zhonghua Wai Ke Za Zhi

[Language] chi

[Publication-type] English Abstract; Journal Article

[Publication-country] China

   

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[Title] [Determinants of long-term survival in 38 patients with carcinoma of ampulla of Vater treated by local resection].

OBJECTIVE: To investigate determinants of long-term survival for carcinoma of ampulla of Vater treated by local resection.

On deciding for resection, the common bile duct was probe explored which guided the circumferential ring resection 1 cm, away from the tumor, including all layers of duodenum, ampula and partial bile and terminal pancreatic ducts and the posterial wall of duodenum was completed in steps.

Meticulous care was taken not to suture the pancreatic duct and endotheliation was ensured at the mouth of common bile duct and duodenum.

Preferably it is indicated only in high risk patients with a pT1 and well differentiated ampullary cancer smaller than 1 cm in diameter.

[MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery

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(PMID = 16438877.001).

[ISSN] 0253-3766

[Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]

[ISO-abbreviation] Zhonghua Zhong Liu Za Zhi

[Language] chi

[Publication-type] English Abstract; Journal Article

[Publication-country] China

   

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These patients included 28 (32%) with pancreatic adenocarcinoma, 18 (20%) with cholangiocarcinoma, 11 (13%) with ampullary carcinoma, 11 (13%) with other primary tumors, 14 (16%) with liver metastases, and 6 (7%) with metastases at other sites.

[MeSH-minor] Antimetabolites, Antineoplastic / administration & dosage. Capecitabine. Dose-Response Relationship, Radiation. Drug Administration Schedule. Gastrointestinal Neoplasms / drug therapy. Gastrointestinal Neoplasms / radiotherapy. Humans. Neoplasm Metastasis. Radiotherapy Dosage. Retrospective Studies. Treatment Outcome

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[Cites] J Clin Oncol. 2000 Mar;18(6):1337-45 [10715306.001]

[Cites] Int J Radiat Oncol Biol Phys. 2005 Oct 1;63(2):346-53 [15913913.001]

[Cites] J Clin Oncol. 2001 Apr 15;19(8):2282-92 [11304782.001]

[Cites] Eur J Cancer. 2002 Feb;38(3):349-58 [11818199.001]

[Cites] Ann Oncol. 2002 Apr;13(4):566-75 [12056707.001]

[Cites] Int J Radiat Oncol Biol Phys. 2002 Jul 1;53(3):675-9 [12062611.001]

[Cites] J Clin Oncol. 2002 Oct 1;20(19):3983-91 [12351595.001]

[Cites] Int J Radiat Oncol Biol Phys. 2004 Jun 1;59(2):454-9 [15145162.001]

[Cites] Br J Cancer. 2004 Sep 13;91(6):1019-24 [15305186.001]

[Cites] J Clin Oncol. 1997 Jan;15(1):110-5 [8996131.001]

[Cites] Eur J Cancer. 1998 Jul;34(8):1274-81 [9849491.001]

[Cites] N Engl J Med. 2005 Jun 30;352(26):2696-704 [15987918.001]

[Cites] Int J Radiat Oncol Biol Phys. 2006 Nov 1;66(3):762-71 [17011451.001]

[Cites] Int J Radiat Oncol Biol Phys. 2005 Dec 1;63(5):1325-30 [15993549.001]

[Cites] J Clin Oncol. 2005 Dec 1;23(34):8679-87 [16314628.001]

[Cites] Ann Oncol. 2006 Feb;17(2):246-51 [16282246.001]

[Cites] J Clin Oncol. 2006 Mar 1;24(7):1145-51 [16505434.001]

[Cites] Eur J Cancer. 2001 Mar;37(5):597-604 [11290435.001]

(PMID = 17062148.001).

[ISSN] 1748-717X

[Journal-full-title] Radiation oncology (London, England)

[ISO-abbreviation] Radiat Oncol

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; 6804DJ8Z9U / Capecitabine; U3P01618RT / Fluorouracil

[Other-IDs] NLM/ PMC1634749

[General-notes] NLM/ Original DateCompleted: 20070808

   

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METHODS: The clinical data of 36 cases receiving duodenopancreatectomy during the last decade were analyzed, including 13 cases of ampullary carcinoma, 8 cases of carcinoma of the pancreas head, 8 cases of distal cholangiocarcinoma, and 7 cases of carcinoma of the duodenal papilla.

RESULTS: Complications occurred in 6 cases after duodenopancreatectomy including pancreatic fistula in 3 cases, bile duct fistula in 1 case, abdominal cavity hemorrhage in 1 case, and alimentary tract hemorrhage in 1 case, with an incidence rate of postoperative complications of 16.7%; and death occurred in 2 cases.

CONCLUSION: Adequate measures should be taken to reduce such complications as pancreatic fistula, bile duct fistula, abdominal cavity hemorrhage, alimentary tract hemorrhage and abdominal cavity infection, and these measures include nutritional support, careful operation in the surgery with adequate drainage, and careful observation and nursing after the surgery.

[MeSH-major] Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / adverse effects. Postoperative Complications / prevention & control

[MeSH-minor] Adult. Aged. China / epidemiology. Common Bile Duct Neoplasms / surgery. Female. Humans. Male. Middle Aged. Pancreatic Fistula / epidemiology. Pancreatic Fistula / etiology. Pancreatic Fistula / prevention & control

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(PMID = 15837657.001).

[ISSN] 1000-2588

[Journal-full-title] Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA

[ISO-abbreviation] Di Yi Jun Yi Da Xue Xue Bao

[Language] chi

[Publication-type] English Abstract; Journal Article

[Publication-country] China

   

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[Title] Does ampullary carcinoma arise from distended glands in the papilla of Vater?

BACKGROUND/PURPOSE: Glands near the surface of the papilla of Vater may become distended with mucus and become hyperplastic; that is, become distended.

METHODS: Twenty-nine pancreatoduodenectomized nontumorous duodenal papilla specimens from carcinoma of the pancreas and bile duct and 34 resected ampullary carcinoma specimens were studied histopathologically and immunohistochemically, using cytokeratins and mucin immunohistochemical features/phenotypes.

Immunopositivity for CK7, CK20, and MUC5AC was found in 25, 21, and 18 of the 34 specimens of ampullary carcinoma, respectively.

CONCLUSIONS: Although most ampullary carcinomas arise from the duodenal mucosa or intra-ampullary mucosa, both CK7-positive and MUC5AC-positive or only MUC5ACpositive ampullary carcinomas may arise from the distended glands.

[MeSH-major] Ampulla of Vater / pathology. Common Bile Duct Neoplasms / metabolism. Common Bile Duct Neoplasms / pathology

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(PMID = 18392709.001).

[ISSN] 0944-1166

[Journal-full-title] Journal of hepato-biliary-pancreatic surgery

[ISO-abbreviation] J Hepatobiliary Pancreat Surg

[Language] eng

[Publication-type] Journal Article

[Publication-country] Japan

[Chemical-registry-number] 0 / Keratin-7; 0 / MUC5AC protein, human; 0 / Mucin 5AC; 0 / Mucins

   

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Carcinoma of the biliary tree are rare tumours of the gastrointestinal tract with a rising incidence during the last years.

Biliary neoplasms are classified into intra- and extrahepatic cholangiocarcinoma (Klatskin tumour, middle and distal extrahepatic tumours), gallbladder cancer, and ampullary carcinoma.

Transformation of normal into malignant bile duct tissue requires a chain of consecutive gene mutations, similar to the adenoma-dysplasia-carcinoma-sequence in colon cancer.

Abdominal ultrasound, combined non-invasive magnetic resonance cholangiography/tomography (MRC/MRT), and facultatively endoscopic retrograde cholangiography (ERC) for unclear diagnosis, represent the gold standard for primary diagnosis.

For ampullary carcinoma, endosonography and endoscopic biopsy are the diagnostic tools of choice.

[MeSH-minor] Algorithms. Ampulla of Vater. Bile Ducts / pathology. Bile Ducts, Intrahepatic. Biopsy. Brachytherapy. Cholangiocarcinoma / diagnosis. Cholangiocarcinoma / therapy. Cholangiopancreatography, Endoscopic Retrograde. Cholangiopancreatography, Magnetic Resonance. Common Bile Duct Neoplasms / diagnosis. Common Bile Duct Neoplasms / therapy. Cyclooxygenase Inhibitors / therapeutic use. Gallbladder / pathology. Hepatectomy. Hepatic Duct, Common. Humans. Klatskin Tumor / diagnosis. Klatskin Tumor / therapy. Magnetic Resonance Imaging. Neoplasm Staging. Palliative Care. Retrospective Studies. Risk Factors. Stents. Time Factors

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[CommentIn] Z Gastroenterol. 2005 May;43(5):473-5 [15871071.001]

(PMID = 15765304.001).

[ISSN] 0044-2771

[Journal-full-title] Zeitschrift für Gastroenterologie

[ISO-abbreviation] Z Gastroenterol

[Language] ger

[Publication-type] Comparative Study; English Abstract; Journal Article; Review

[Publication-country] Germany

[Chemical-registry-number] 0 / Cyclooxygenase Inhibitors

[Number-of-references] 153

   

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The tumor involving thoraco-abdominal cavity was in one case with malignant neuroblastoma.

Tumor located in thoracic cavity were in 13 cases including IVC leiomyosarcoma in 2 cases, thymic carcinoma in 3 cases, malignant thymoma in 4 cases, malignant seminoma of superior mediastinum in 1 case, malignant lymphoma in 1 case, lung cancer in 2 cases.

The tumor located in abdominal cavity were in 24 cases including renal carcinoma with tumor thrombi in 11 cases, inflammatory pseudotumor of retro-peritoneum in 4 cases, malignant fibrous histiocytoma of retro-peritoneum in 1 case, non-Hodgkin's disease of retro-peritoneum in 1 case, lymph metastasis of retro-peritoneum in 2 cases, paraganglion tumor of the right adrenal gland in 1 case, ampullary carcinoma in 1 case, leiomyosarcoma of abdominal IVC in 1 case, leiomyosarcoma of pelvic cavity and IVC in 1 cases, fibrosarcoma of pelvic cavity in 1 case.

[MeSH-minor] Adolescent. Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness. Retrospective Studies. Treatment Outcome. Vena Cava, Inferior / pathology. Vena Cava, Inferior / surgery

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(PMID = 18005586.001).

[ISSN] 0529-5815

[Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]

[ISO-abbreviation] Zhonghua Wai Ke Za Zhi

[Language] chi

[Publication-type] English Abstract; Journal Article

[Publication-country] China

   

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[Title] Clinical significance of immunohistochemically detectable lymph node metastasis in adenocarcinoma of the ampulla of Vater.

BACKGROUND: The aim of this study was to assess the impact of immunohistochemically identified lymph node metastasis on survival in patients with carcinoma of the ampulla of Vater.

METHODS: Three hundred and twenty-six regional lymph nodes dissected from pancreatoduodenectomy specimens from 25 patients with ampulla of Vater carcinoma were immunostained with anticytokeratin antibody (CAM 5.2).

CONCLUSION: Immunostaining of dissected lymph nodes adds additional information to data obtained by conventional haematoxylin and eosin staining when determining the prognosis of patients with carcinoma of the ampulla of Vater.

[MeSH-major] Adenocarcinoma / secondary. Ampulla of Vater / pathology. Common Bile Duct Neoplasms / pathology

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[Copyright] Copyright (c) 2005 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

(PMID = 16363020.001).

[ISSN] 0007-1323

[Journal-full-title] The British journal of surgery

[ISO-abbreviation] Br J Surg

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

   

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RESULTS: The procedure could be completed laparoscopically with tumor-free margins in all patients, including patients with ampullary carcinoma (n = 24), pancreatic cystadenocarcinoma (n = 4), pancreatic head adenocarcinoma (n = 9), low common bile duct cancer (n = 3), and two patients with chronic pancreatitis with a suspicious mass lesion in the head of pancreas.

Five-year actuarial survival rates for all patients with malignancy, ampullary adenocarcinoma, pancreatic cystadenocarcinoma, pancreatic head adenocarcinoma, and common bile duct adenocarcinoma are 32%, 30.7%, 33.3%, 19.1%, and 50%, respectively.

Localized malignant lesions, irrespective of histopathology, are particularly amenable to this approach.

[MeSH-major] Duodenal Neoplasms / surgery. Laparoscopy. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods

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(PMID = 17660068.001).

[ISSN] 1072-7515

[Journal-full-title] Journal of the American College of Surgeons

[ISO-abbreviation] J. Am. Coll. Surg.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

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BACKGROUND: Non-pancreatic periampullary carcinoma such as ampullary carcinoma (AmpCA), distal cholangiocellular carcinoma (CholCA) and duodenal carcinoma (DuoCA) have a better prognosis than pancreatic head adenocarcinoma (PanCA).

This study describes the outcome and parameters, which predict survival of non-pancreatic periampullary carcinoma after resection.

METHODS AND PATIENTS: Data from 148 consecutive patients with non-pancreatic periampullary carcinomas were recorded prospectively between 1993 and 2005 and analyzed using univariate and multivariate models.

RESULTS: One hundred thirty-three of 148 (90%) patients were resected for histologically proven non-pancreatic periampullary carcinomas.

CONCLUSION: Only T1/T2 ampullary carcinomas have a good prognosis, whereas T3/T4 ampullary tumors show aggressiveness similar to that of pancreatic head adenocarcinomas.

[MeSH-major] Ampulla of Vater. Biliary Tract Surgical Procedures / methods. Carcinoma / surgery. Clinical Audit / methods. Common Bile Duct Neoplasms / surgery

[MeSH-minor] Aged. Female. Follow-Up Studies. Humans. Incidence. Male. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Prospective Studies. Survival Rate. Treatment Outcome

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(PMID = 18343082.001).

[ISSN] 1532-2157

[Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

[ISO-abbreviation] Eur J Surg Oncol

[Language] eng

[Publication-type] Comparative Study; Journal Article; Multicenter Study

[Publication-country] England

   

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METHODS: Patients with histologically proven BTCs, including cholangiocarcinoma or gallbladder and ampullary carcinomas, were treated with a maximum of nine cycles of intravenous (i.v.) gemcitabine at 1000 mg/m(2) over 30 min on days 1 and 8 with i.v. carboplatin dosed at an area-under-the-curve (AUC) of 5 over 60 min on day 1 of a 21-day cycle.

RESULTS: A total of 48 patients with advanced BTCs (35 cholangiocarcinoma, 12 gallbladder and 1 ampullary cancer) were enrolled.

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[Cites] Am J Clin Oncol. 2000 Aug;23(4):425-8 [10955877.001]

[Cites] N Engl J Med. 2010 Apr 8;362(14):1273-81 [20375404.001]

[Cites] Hepatogastroenterology. 2001 May-Jun;48(39):783-9 [11462924.001]

[Cites] Eur J Cancer. 2001 Oct;37(15):1833-8 [11576836.001]

[Cites] J Clin Oncol. 2001 Oct 15;19(20):4089-91 [11600613.001]

[Cites] Cancer. 2002 Oct 15;95(8):1685-95 [12365016.001]

[Cites] Invest New Drugs. 2004 Apr;22(2):193-8 [14739669.001]

[Cites] Ann Oncol. 2004 Sep;15(9):1339-43 [15319238.001]

[Cites] Cancer. 1974 Jan;33(1):193-7 [4272473.001]

[Cites] Br J Surg. 1974 Feb;61(2):98-100 [4361236.001]

[Cites] Ann Surg. 1982 Mar;195(3):270-3 [7059239.001]

[Cites] Cancer. 1984 Sep 15;54(6):965-9 [6235908.001]

[Cites] J Clin Oncol. 1984 Nov;2(11):1245-8 [6092556.001]

[Cites] Ann Surg. 1988 Feb;207(2):120-5 [2829760.001]

[Cites] Control Clin Trials. 1989 Mar;10(1):1-10 [2702835.001]

[Cites] Surg Clin North Am. 1990 Dec;70(6):1429-47 [2174191.001]

[Cites] Arch Surg. 1993 Aug;128(8):871-7; discussion 877-9 [8393652.001]

[Cites] Ann Oncol. 1993 Aug;4(7):607-9 [8363992.001]

[Cites] J Surg Oncol. 1994 Apr;55(4):239-45 [8159005.001]

[Cites] Am J Clin Oncol. 1994 Jun;17(3):223-6 [8192106.001]

[Cites] Ann Oncol. 1996 Aug;7(6):593-600 [8879373.001]

[Cites] Oncol Rep. 1998 Jul-Aug;5(4):931-4 [9625849.001]

[Cites] Oncology. 1999 Apr;56(3):177-80 [10202270.001]

[Cites] Br J Cancer. 2004 Nov 15;91(10):1769-74 [15505626.001]

[Cites] Cancer. 2005 Jan 1;103(1):111-8 [15558814.001]

[Cites] Jpn J Clin Oncol. 2005 Feb;35(2):68-73 [15709089.001]

[Cites] Ann Oncol. 2005;16 Suppl 2:ii93-6 [15958484.001]

[Cites] Int J Radiat Oncol Biol Phys. 2005 Jul 15;62(4):1030-4 [15990005.001]

[Cites] BMC Cancer. 2005;5:61 [15949047.001]

[Cites] Cancer Chemother Pharmacol. 2006 May;57(5):647-53 [16142487.001]

[Cites] Cancer. 2006 Mar 15;106(6):1339-46 [16475213.001]

[Cites] Br J Cancer. 2006 Oct 9;95(7):848-52 [16969352.001]

[Cites] J Clin Oncol. 2006 Oct 10;24(29):4699-707 [16966687.001]

[Cites] Br J Cancer. 2007 Mar 26;96(6):896-902 [17325704.001]

[Cites] Eur Urol. 2007 Jul;52(1):134-41 [17207911.001]

[Cites] J Natl Cancer Inst. 2007 Jun 6;99(11):847-57 [17551145.001]

[Cites] Cancer. 2007 Sep 15;110(6):1307-12 [17628484.001]

[Cites] Dig Dis Sci. 2008 Feb;53(2):564-70 [17597402.001]

[Cites] CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96 [18287387.001]

[Cites] J Clin Oncol. 2008 Aug 1;26(22):3702-8 [18669455.001]

[Cites] Clin Breast Cancer. 2008 Oct;8(5):425-31 [18952556.001]

[Cites] Eur J Cancer. 2009 Jan;45(2):228-47 [19097774.001]

[Cites] Cancer Chemother Pharmacol. 2009 Jul;64(2):371-7 [19142638.001]

[Cites] Ann Oncol. 2001 Feb;12(2):183-6 [11300321.001]

(PMID = 20662793.001).

[ISSN] 1477-2574

[Journal-full-title] HPB : the official journal of the International Hepato Pancreato Biliary Association

[ISO-abbreviation] HPB (Oxford)

[Language] eng

[Databank-accession-numbers] ClinicalTrials.gov/ NCT00660140

[Publication-type] Clinical Trial, Phase II; Journal Article

[Publication-country] England

[Chemical-registry-number] 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine; BG3F62OND5 / Carboplatin

[Other-IDs] NLM/ PMC3028583

   

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[Title] Significant overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma using real-time quantitative reverse transcription polymerase chain reaction.

It was hypothesized that uPA would be overexpressed in highly metastatic pancreatic cancer.

The aims of this study were to analyze uPA mRNA expression in pancreatic cancer and to correlate this to the expression of uPA protein and to the stage of the disease.

METHODS: Twenty-one pancreatic adenocarcinoma, six ampullary carcinoma and 10 benign mucinous cystadenoma samples, all with adjacent normal tissue, were collected. uPA mRNA was measured using real-time quantitative reverse transcription polymerase chain reaction.

Localization of uPA within normal and pancreatic tumor sections was subsequently confirmed using immunohistochemistry.

RESULTS: The median and range of the ratios of uPA mRNA measures between tumor tissue and non-involved pancreatic tissue was 17.1 (1.4-653.6) for pancreatic adenocarcinoma (P < 0.001), 3.9 (0.7-7.7) for ampullary carcinoma (P = 0.055) and 1.9 (0.6-5.9) for mucinous cystadenoma tissue (P = 0.052).

Immunohistochemistry confirmed that uPA protein was more prevalent in pancreatic adenocarcinoma tissue than in normal tissue and that it was membrane-bound. uPA mRNA expression was significantly associated with poorly differentiated pancreatic cancers (P < 0.05) and positively associated with tumor stage.

CONCLUSIONS: These observations suggest that significant overexpression of uPA correlates closely to the rapid progression and invasiveness of pancreatic cancer and that uPA may provide a future therapeutic target for pancreatic cancer treatment.

[MeSH-major] Adenocarcinoma / genetics. Pancreatic Neoplasms / genetics. Urokinase-Type Plasminogen Activator / genetics

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[Copyright] (c) 2004 Blackwell Publishing Asia Pty Ltd.

(PMID = 15683429.001).

[ISSN] 0815-9319

[Journal-full-title] Journal of gastroenterology and hepatology

[ISO-abbreviation] J. Gastroenterol. Hepatol.

[Language] eng

[Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Australia

[Chemical-registry-number] 0 / RNA, Messenger; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator

   

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METHODS: A retrospective study was accomplished on the clinical manifestation, pathological behavior and postoperative survival of 631 patients with periampullary cancer hospitalized from Jan 1980 to Dec 2003.

RESULTS: The characteristics of different periampullary cancers, in the order of carcinoma of head of pancreas (n = 352), carcinoma of common bile duct (n = 42), carcinoma of Vater's ampulla (n = 189), and duodenal cancer (n = 48) were as follows:.

[MeSH-major] Ampulla of Vater. Common Bile Duct Neoplasms / pathology. Pancreatic Neoplasms / pathology

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(PMID = 15949327.001).

[ISSN] 0376-2491

[Journal-full-title] Zhonghua yi xue za zhi

[ISO-abbreviation] Zhonghua Yi Xue Za Zhi

[Language] chi

[Publication-type] English Abstract; Journal Article

[Publication-country] China

   

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[Title] Expression of E-cadherin and beta-catenin in the adenoma-carcinoma sequence of ampulla of Vater cancer.

BACKGROUND/AIMS: Ampullary carcinoma is uncommon but provides a good model for adenoma-carcinoma sequence.

During the adenoma-carcinoma transition, the tumor cells should acquire the ability to invade.

METHODOLOGY: 111 cases of ampullary carcinoma were investigated with E-cadherin and beta-catenin expression with immunohistochemistry and the result was compared with their clinicopathologic and survival results.

RESULTS: Expressional loss of E-cadherin was detected in 3 (6.1%) adenomas and 73 (65.8%) carcinomas, and the expressional loss was significantly associated with tumor cell differentiation (p<0.05) and survival (p<0.05) in carcinoma.

CONCLUSIONS: Alteration of E-cadherin and beta-catenin is a late event during the adenoma-carcinoma sequence in ampullary neoplasms, and the loss of membranous expression of both E-cadherin and beta-catenin is closely correlated with less differentiated histology and poor prognosis.

[MeSH-major] Adenoma / metabolism. Adenoma / pathology. Ampulla of Vater. Cadherins / biosynthesis. Carcinoma / metabolism. Carcinoma / pathology. Common Bile Duct Neoplasms / metabolism. Common Bile Duct Neoplasms / pathology. beta Catenin / biosynthesis

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(PMID = 16506371.001).

[ISSN] 0172-6390

[Journal-full-title] Hepato-gastroenterology

[ISO-abbreviation] Hepatogastroenterology

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Greece

[Chemical-registry-number] 0 / Cadherins; 0 / beta Catenin

   

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[Title] Predictors of recurrence after pancreaticoduodenectomy in ampullary cancer: comparison between non-, early and late recurrence.

BACKGROUND/PURPOSE: Ampullary cancer is one of the periampullary cancers with a better prognosis, but relapse still occurs early in some patients.

METHODS: Between January 1989 and March 2006, information was gathered on a total of 127 patients undergoing pancreaticoduodenectomy with regional lymphadenectomy for ampullary cancer at National Cheng Kung University Hospital and Tainan Municipal Hospital.

The early and late recurrence patients had higher levels of microscopically (R1) or macroscopically (R2) positive margin of resection and more advanced disease (advanced tumor stage, numbers of lymph nodes involved, lymph node status, pancreatic invasion and TNM stage) than the non-recurrence group.

After multivariate analysis, positive resection margin, pancreatic invasion and lymph node involvement were significant predictors for disease recurrence.

CONCLUSION: Positive resection margin, pancreatic invasion, and lymph node involvement were found to be predictors for disease recurrence and indicators for postoperative treatment.

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(PMID = 17588836.001).

[ISSN] 0929-6646

[Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi

[ISO-abbreviation] J. Formos. Med. Assoc.

[Language] ENG

[Publication-type] Comparative Study; Journal Article

[Publication-country] Singapore

   

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[Title] Prospective evaluation of EUS versus CT scan for staging of ampullary cancer.

BACKGROUND: Malignancies of the biliary and pancreatic systems are associated with a poor prognosis.

However, ampullary cancer carries a better prognosis and is often diagnosed when curative treatment is still possible.

(1) To determine the test performance characteristics of EUS and CT in loco-regional staging of ampullary neoplasms, and (2) to determine the impact of CT scan results on the test performance characteristics of EUS.

Further studies to determine the role of specialized CT protocols in patients with ampullary malignancies are needed.

[MeSH-major] Adenocarcinoma / pathology. Ampulla of Vater. Common Bile Duct Neoplasms / pathology. Endosonography. Tomography, X-Ray Computed

[MeSH-minor] Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prospective Studies

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(PMID = 19523619.001).

[ISSN] 1097-6779

[Journal-full-title] Gastrointestinal endoscopy

[ISO-abbreviation] Gastrointest. Endosc.

[Language] eng

[Publication-type] Comparative Study; Journal Article

[Publication-country] United States

   

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[Title] Stromal osteonectin overexpression is associated with poor outcome in patients with ampullary cancer.

BACKGROUND: Osteonectin has been suggested to be important in the progression of pancreatic cancer but has not been correlated with survival.

We determined the osteonectin expression and its influence on survival in patients with ampullary carcinoma.

METHODS: Tissue microarrays were constructed from the tumors of 56 patients with ampullary cancer undergoing pancreaticoduodenectomy.

Median follow-up for all living patients with ampullary cancer was 69.6 months.

RESULTS: Osteonectin was significantly (P < .05, Fisher's exact test) overexpressed in the stroma of ampullary cancers (90%) relative to chronic pancreatitis (62%) and normal pancreas (0%).

CONCLUSIONS: Although the importance of tumor-stroma interactions in periampullary cancers is not fully understood, our data suggest that osteonectin is an integral stromal element in ampullary cancers, and its overexpression is associated with decreased survival.

[MeSH-major] Adenocarcinoma / chemistry. Ampulla of Vater. Biomarkers, Tumor / analysis. Common Bile Duct Neoplasms / chemistry. Osteonectin / analysis

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(PMID = 17080236.001).

[ISSN] 1068-9265

[Journal-full-title] Annals of surgical oncology

[ISO-abbreviation] Ann. Surg. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MUC2 protein, human; 0 / Mucin-1; 0 / Mucin-2; 0 / Mucins; 0 / Osteonectin; 106441-73-0 / Osteopontin

   

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[Title] Primary acinar cell carcinoma of the ampulla of Vater.

Acinar cell carcinoma of the pancreatobiliary system is a relatively rare malignant neoplasm arising usually in the pancreatic parenchyma.

We experienced a 68-year-old woman who presented with obstructive jaundice due to an ampullary mass 1.0 cm in diameter, detected by abdominal computed tomography and endoscopic examination.

The patient underwent a curative surgical operation, and histopathological examination revealed that the tumor was confined to the ampulla of Vater with no continuity to the pancreatic parenchyma.

The tumor cells showed acinar or tubular arrangement with eosinophilic to basophilic granular cytoplasm, findings identical to those of acinar cell carcinoma of the pancreas.

From these findings, we concluded that the tumor was primary acinar cell carcinoma arising in the ampulla of Vater, probably originating from heterotopic pancreatic tissue.

This is the first reported case of primary acinar cell carcinoma in the ampulla of Vater.

[MeSH-major] Ampulla of Vater. Carcinoma, Acinar Cell / diagnosis. Common Bile Duct Neoplasms / diagnosis

[MeSH-minor] Biopsy. Diagnosis, Differential. Endosonography. Female. Follow-Up Studies. Humans. Middle Aged. Pancreaticoduodenectomy / methods. Tomography, X-Ray Computed

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[Cites] Arch Pathol Lab Med. 2001 Aug;125(8):1127-8 [11473479.001]

[Cites] Dig Surg. 2005;22(5):377-9 [16432300.001]

[Cites] Arch Pathol Lab Med. 1994 May;118(5):568-71 [8192567.001]

[Cites] Hum Pathol. 2004 Feb;35(2):263-5 [14991547.001]

[Cites] Gastrointest Endosc. 2001 Jan;53(1):121-3 [11154509.001]

[Cites] Am J Surg Pathol. 1992 Sep;16(9):815-37 [1384374.001]

[Cites] Arch Pathol Lab Med. 1999 Aug;123(8):707-11 [10420228.001]

[Cites] Am J Clin Oncol. 1997 Feb;20(1):101-7 [9020300.001]

[Cites] Hum Pathol. 2002 Apr;33(4):449-51 [12055683.001]

(PMID = 17701134.001).

[ISSN] 0944-1174

[Journal-full-title] Journal of gastroenterology

[ISO-abbreviation] J. Gastroenterol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Japan

   

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[Title] Risk factors of pancreatic leakage after pancreaticoduodenectomy.

AIM: To analyze the risk factors for pancreatic leakage after pancreaticoduodenectomy (PD) and to evaluate whether duct-to-mucosa pancreaticojejunostomy could reduce the risk of pancreatic leakage.

The primary diseases of the patients included pancreas cancer, ampullary cancer, bile duct cancer, islet cell cancer, duodenal cancer, chronic pancreatitis, pancreatic cystadenoma, and gastric cancer.

A duct-to-mucosa pancreaticojejunostomy was performed for patients with a hard pancreas and a dilated pancreatic duct, and a traditional end-to-end invagination pancreaticojejunostomy for patients with a soft pancreas and a non-dilated duct.

Seven preoperative and six intraoperative risk factors with the potential to affect the incidence of pancreatic leakage were analyzed with SPSS10.0 software.

Logistic regression was then used to determine the effect of multiple factors on pancreatic leakage.

RESULTS: Of the 62 patients, 10 (16.13%) were identified as having pancreatic leakage after operation.

The hospital mortality in this series was 4.84% (3/62), and the mortality associated with pancreatic fistula was 10% (1/10).

Sixteen cases underwent duct-to-mucosa pancreaticojejunostomy and 1 case (1/16, 6.25%) developed postoperative pancreatic leakage, 46 cases underwent invagination pancreaticojejunostomy and 9 cases (9/46, 19.6%) developed postoperative pancreatic leakage.

General risk factors including patient age, gender, history of jaundice, preoperative nutrition, pathological diagnosis and the length of postoperative stay were similar in the two groups.

There was no statistical difference in the incidence of pancreatic leakage between the patients who received the prophylactic use of octreotide after surgery and the patients who did not undergo somatostatin therapy.

Moreover, multivariate logistic regression analysis showed that none of the above factors seemed to be associated with pancreatic fistula.

Two intraoperative risk factors, pancreatic duct size and texture of the remnant pancreas, were found to be significantly associated with pancreatic leakage.

The incidence of pancreatic leakage was 4.88% in patients with a pancreatic duct size greater than or equal to 3 mm and was 38.1% in those with ducts smaller than 3 mm (P = 0.002).

The pancreatic leakage rate was 2.94% in patients with a hard pancreas and was 32.1% in those with a soft pancreas (P = 0.004).

The incidence of pancreatic leakage was 6.25% (1/16) in patients with duct-to-mucosa anastomosis, and was 19.6% (9/46) in those with traditional invagination anastomosis.

Although the difference of pancreatic leakage between the two groups was obvious, no statistical significance was found.

By further analyzing with multivariate logistic regression, both pancreatic duct size and texture of the remnant pancreas were demonstrated to be independent risk factors (P = 0.007 and 0.017, OR = 11.87 and 15.45).

Although anastomotic technique was not a significant factor, pancreatic leakage rate was much less in cases that underwent duct-to-mucosa pancreaticojejunostomy.

CONCLUSION: Pancreatic duct size and texture of the remnant pancreas are risk factors influencing pancreatic leakage after PD.

Duct-to-mucosa pancreaticojejunostomy, as a safe and useful anastomotic technique, can reduce pancreatic leakage rate after PD.

[MeSH-major] Intraoperative Complications / epidemiology. Pancreatic Diseases / epidemiology. Pancreatic Diseases / surgery. Pancreaticoduodenectomy / adverse effects. Postoperative Complications / epidemiology

[MeSH-minor] Adult. Aged. Duodenum / surgery. Female. Humans. Male. Middle Aged. Pancreas / surgery. Pancreatic Ducts / surgery. Risk Factors

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(PMID = 15832417.001).

[ISSN] 1007-9327

[Journal-full-title] World journal of gastroenterology

[ISO-abbreviation] World J. Gastroenterol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] China

[Other-IDs] NLM/ PMC4305634

   

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[Title] KL-6 mucin expression in carcinoma of the ampulla of Vater: association with cancer progression.

AIM: To assess histochemical expression of KL-6 and its clinicopathological significance in carcinoma of the ampulla of Vater.

METHODS: Ampullary carcinoma tissues were collected from 38 patients who underwent pancreatoduodenectomy or local resection.

RESULTS: Positive staining of ampullary carcinoma cells was observed in 26 (68.4%) cases.

Staining was not found in the surrounding non-cancer regions of the ampullary tissues.

Remarkable KL-6 expression was observed in invasive carcinoma cells in pancreatic and duodenal tissues and in metastatic carcinoma cells in lymph nodes.

Positive KL-6 expression was related to lymph node metastasis (P = 0.020), pancreatic invasion (P = 0.016), duodenal invasion (P = 0.034), and advanced stage of TNM clinical classification (P = 0.010).

CONCLUSION: The aberrant expression of KL-6 mucin is significantly related to unfavorable behaviors of carcinoma of the ampulla of Vater.

[MeSH-major] Ampulla of Vater. Antigens / metabolism. Common Bile Duct Neoplasms / metabolism. Glycoproteins / metabolism. Mucins / metabolism

[MeSH-minor] Aged. Aged, 80 and over. Antigens, Neoplasm. Female. Humans. Immunohistochemistry. Male. Middle Aged. Mucin-1

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(PMID = 16222735.001).

[ISSN] 1007-9327

[Journal-full-title] World journal of gastroenterology

[ISO-abbreviation] World J. Gastroenterol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] China

[Chemical-registry-number] 0 / Antigens; 0 / Antigens, Neoplasm; 0 / Glycoproteins; 0 / MUC1 protein, human; 0 / Mucin-1; 0 / Mucins

[Other-IDs] NLM/ PMC4320352

   

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[Title] Spondyloarthropathy after ampullary carcinoma resection: "post-Whipple" disease.

The development of bowel-bypass syndrome complicating the Whipple procedure for biliary tract carcinoma is described here for the first time.

A 56-year-old HLA-B27 + man, treated with excision of adenocarcinoma of the ampulla of Vater, developed an undifferentiated spondyloarthropathy, initially unresponsive to nonsteroidal anti-inflammatory drugs and doxycycline, but eventually controlled with sulfasalazine and tapered corticosteroids.

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(PMID = 19590445.001).

[ISSN] 1536-7355

[Journal-full-title] Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

[ISO-abbreviation] J Clin Rheumatol

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Adrenal Cortex Hormones

   

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[Title] Intraoperative allogeneic red blood cell transfusion in ampullary cancer outcome after curative pancreatoduodenectomy: a clinical study and meta-analysis.

BACKGROUND: Allogeneic blood transfusion (ABT) containing packed red blood cells (RBCs) has a known immunosuppressive effect that may affect cancer metastases and recurrence.

This study examined whether intraoperative allogeneic RBC transfusion is an independent risk factor of adverse outcome in patients with ampullary carcinoma after curative pancreatoduodenectomy.

METHODS: The clinical data of 67 patients with carcinoma of the ampulla of Vatar underwent pancreatoduodenectomy between 1999 and 2004 were analyzed, and long-term follow-up visits were made for all patients.

For the meta-analysis, all English-language studies regarding blood transfusion from carcinoma of the ampulla of Vatar or ampullary carcinoma and prognostic factors or factors for survival from 1995 to 2007 were reviewed, and contingency tables were constructed from which a summary relative risk was calculated.

After multivariate analysis, except for presence of lymph node metastasis (P = 0.023) and pancreatic invasion (P = 0.024), the intraoperative ABT > or =3 units was found to be an independent poor prognostic factor for those with ampullary cancer after curative pancreatoduodenectomy either (relative risk, 2.082; 95% confidence interval (CI), 1.048-4.135; P = 0.036).

CONCLUSIONS: The amount of intraoperative ABT is one of the important factors that adversely influenced survival in patients with ampullary cancer after curative pancreatoduodenectomy.

[MeSH-major] Ampulla of Vater / surgery. Erythrocyte Transfusion. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy

[MeSH-minor] Adult. Aged. Blood Loss, Surgical. Blood Transfusion, Autologous. Chi-Square Distribution. Female. Humans. Intraoperative Care. Male. Middle Aged. Neoplasm Staging. Prognosis. Proportional Hazards Models. Risk Factors. Survival Analysis. Treatment Outcome

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[Cites] Ann Surg. 1997 May;225(5):590-9; discussion 599-600 [9193186.001]

[Cites] Am J Surg. 1991 Jan;161(1):120-4; discussion 124-5 [1987845.001]

[Cites] J Clin Epidemiol. 1991;44(2):127-39 [1995774.001]

[Cites] Ann Surg. 1998 Jul;228(1):87-94 [9671071.001]

[Cites] Surgery. 1985 Feb;97(2):225-30 [3969625.001]

[Cites] J Surg Oncol. 2000 Dec;75(4):258-63 [11135267.001]

[Cites] Surg Today. 1998;28(6):576-9 [9681604.001]

[Cites] Blood. 1984 Jul;64(1):308-10 [6234037.001]

[Cites] Jpn J Clin Oncol. 1993 Oct;23(5):299-302 [8230754.001]

[Cites] Control Clin Trials. 1986 Sep;7(3):177-88 [3802833.001]

[Cites] Lancet. 1977 Mar 5;1(8010):506-9 [65609.001]

[Cites] Am J Surg. 2003 Mar;185(3):188-93 [12620553.001]

[Cites] World J Surg. 2002 Apr;26(4):487-92 [11910485.001]

[Cites] Ann Thorac Surg. 1989 Mar;47(3):346-51 [2539064.001]

[Cites] Pancreas. 2006 May;32(4):390-5 [16670621.001]

[Cites] Dis Colon Rectum. 1990 Feb;33(2):127-30 [2298098.001]

[Cites] J Surg Res. 1990 May;48(5):498-503 [2352426.001]

[Cites] Cancer. 1987 Feb 1;59(3):506-15 [3791159.001]

[Cites] Transfusion. 1999 Jul;39(7):718-23 [10413279.001]

[Cites] World J Surg. 2007 Jan;31(1):137-43; discussion 144-6 [17171495.001]

[Cites] Lancet. 1982 Sep 18;2(8299):662 [6125797.001]

[Cites] Ann Surg Oncol. 2002 Jan-Feb;9(1):5-12 [11829431.001]

[Cites] Dis Colon Rectum. 2006 Aug;49(8):1116-30 [16779711.001]

[Cites] Br J Urol. 1992 Aug;70(2):135-8 [1393434.001]

[Cites] Plast Reconstr Surg. 2007 Jun;119(7):2001-7 [17519691.001]

[Cites] Br J Surg. 2003 Sep;90(9):1131-6 [12945082.001]

[Cites] Yale J Biol Med. 1988 Nov-Dec;61(6):493-500 [3242314.001]

[Cites] Cancer. 1989 Oct 15;64(8):1727-37 [2790686.001]

[Cites] Am J Surg. 1988 Nov;156(5):374-80 [3189708.001]

[Cites] Ann Surg. 2007 Feb;245(2):187-200 [17245171.001]

[Cites] Transplant Proc. 1988 Dec;20(6):1121-4 [3201556.001]

[Cites] Transplantation. 1978 Oct;26(4):255-9 [360527.001]

[Cites] Ann Surg. 1988 Dec;208(6):679-87 [3196088.001]

[Cites] Transplantation. 1997 Apr 15;63(7):964-7 [9112348.001]

[Cites] Rev Gastroenterol Mex. 2006 Jul-Sep;71(3):252-6 [17140045.001]

[Cites] Ann Surg. 1977 Jan;185(1):52-7 [831636.001]

[Cites] World J Surg. 2005 Apr;29(4):513-8 [15776300.001]

[Cites] Transplant Proc. 1979 Mar;11(1):127-37 [109959.001]

[Cites] Dis Colon Rectum. 2001 Jul;44(7):955-64 [11496075.001]

[Cites] Arch Otolaryngol Head Neck Surg. 2002 Mar;128(3):308-12 [11886349.001]

[Cites] World J Surg. 2007 Oct;31(10):2044-51 [17671807.001]

[Cites] Immunol Invest. 1995 Jan-Feb;24(1-2):311-7 [7713592.001]

(PMID = 18584239.001).

[ISSN] 0364-2313

[Journal-full-title] World journal of surgery

[ISO-abbreviation] World J Surg

[Language] eng

[Publication-type] Journal Article; Meta-Analysis

[Publication-country] United States

   

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[Title] Malignant afferent loop obstruction following pancreaticoduodenectomy: report of two cases.

We report two cases of malignant afferent loop obstruction following pancreaticoduodenectomy (PD). Case 1.

A 70-year-old woman, who had undergone PD for pancreatic cancer, was referred to our hospital because of fever, jaundice, and abdominal pain.

Laparotomy confirmed the diagnosis of local recurrent tumor causing occlusion of the afferent limb, and Roux-en-Y bypass was performed. Case 2.

A 72-year-old man, who had undergone PD for cancer of the major papilla, was hospitalized with a high-grade fever and epigastric pain.

[MeSH-minor] Aged. Ampulla of Vater. Carcinoma / complications. Common Bile Duct Neoplasms / complications. Female. Humans. Male. Neoplasm Recurrence, Local. Pancreatic Neoplasms / complications. Postoperative Complications

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(PMID = 16936449.001).

[ISSN] 1345-4676

[Journal-full-title] Journal of Nippon Medical School = Nippon Ika Daigaku zasshi

[ISO-abbreviation] J Nippon Med Sch

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Japan

   

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[Title] Ampullary adenocarcinoma - differentiation matters.

This fuels the discussion about maintaining ampullary cancer as a separate entity.

[MeSH-major] Adenocarcinoma / diagnosis. Ampulla of Vater / pathology. Common Bile Duct Neoplasms / diagnosis

[MeSH-minor] Biomarkers, Tumor. Cell Differentiation. Diagnosis, Differential. Epithelium / pathology. Humans. Medical Oncology / methods. Prognosis

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[Cites] J Clin Oncol. 2001 May 1;19(9):2422-32 [11331321.001]

[Cites] Jpn J Cancer Res. 1994 Feb;85(2):161-6 [7511574.001]

[Cites] Eur J Surg Oncol. 2009 Feb;35(2):187-91 [18343082.001]

[Cites] Surgery. 2006 Nov;140(5):764-72 [17084719.001]

[Cites] BMC Cancer. 2008;8:170 [18547417.001]

[Cites] Arch Surg. 1999 May;134(5):526-32 [10323425.001]

(PMID = 18761739.001).

[ISSN] 1471-2407

[Journal-full-title] BMC cancer

[ISO-abbreviation] BMC Cancer

[Language] eng

[Publication-type] Editorial

[Publication-country] England

[Chemical-registry-number] 0 / Biomarkers, Tumor

[Other-IDs] NLM/ PMC2553420

   

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[Title] Flowcharts for the management of biliary tract and ampullary carcinomas.

No strategies for the diagnosis and treatment of biliary tract carcinoma have been clearly described.

We developed flowcharts for the diagnosis and treatment of biliary tract carcinoma on the basis of the best clinical evidence.

Risk factors for bile duct carcinoma are a dilated type of pancreaticobiliary maljunction (PBM) and primary sclerosing cholangitis.

A nondilated type of PBM is a risk factor for gallbladder carcinoma.

Symptoms that may indicate biliary tract carcinoma are jaundice and pain in the upper right area of the abdomen.

The first step of diagnosis is to carry out blood biochemistry tests and ultrasonography (US) of the abdomen.

The second step of diagnosis is to find the local extension of the carcinoma by means of computed tomography (CT), magnetic resonance imaging (MRI), magnetic resonance cholangiopancreatography (MRCP), percutaneous transhepatic cholangiography (PTC), and endoscopic retrograde cholangiopancreatography (ERCP).

Because resection is the only way to completely cure biliary tract carcinoma, the indications for resection are determined first.

[MeSH-major] Algorithms. Ampulla of Vater. Biliary Tract Neoplasms. Carcinoma

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[Cites] Surgery. 1985 Oct;98(4):752-9 [4049246.001]

[Cites] Lancet. 1987 Jul 11;2(8550):57-62 [2439854.001]

[Cites] J Gastroenterol Hepatol. 2003 Aug;18(8):950-3 [12859725.001]

[Cites] Ann Intern Med. 2003 Oct 7;139(7):547-57 [14530225.001]

[Cites] Ann Surg. 2003 Nov;238(5):720-7 [14578735.001]

[Cites] Gastroenterology. 2003 Nov;125(5):1355-63 [14598251.001]

[Cites] J Hepatobiliary Pancreat Surg. 2003;10(5):345-51 [14598134.001]

[Cites] Clin Gastroenterol Hepatol. 2004 Apr;2(4):273-85 [15067620.001]

[Cites] Gut. 2004 May;53(5):729-34 [15082593.001]

[Cites] Ann Surg. 1991 Jan;213(1):21-5 [1845927.001]

[Cites] J Nucl Med Allied Sci. 1990 Oct-Dec;34(4 Suppl):97-102 [2092159.001]

[Cites] Am J Surg. 1991 Apr;161(4):454-8 [1709795.001]

[Cites] Semin Liver Dis. 1991 Feb;11(1):26-30 [1646485.001]

[Cites] Br J Surg. 1991 Jun;78(6):727-31 [2070244.001]

[Cites] World J Surg. 1991 May-Jun;15(3):357-66 [1853615.001]

[Cites] Eur J Surg. 1991 Oct;157(10):587-9 [1687249.001]

[Cites] Anticancer Res. 1992 Sep-Oct;12(5):1687-93 [1332581.001]

[Cites] Lancet. 1992 Dec 19-26;340(8834-8835):1488-92 [1281903.001]

[Cites] Endoscopy. 1993 Jan;25(1):76-80 [8384103.001]

[Cites] J Surg Oncol Suppl. 1993;3:131-3 [8389160.001]

[Cites] Endoscopy. 1993 Mar;25(3):213-8 [7686100.001]

[Cites] Mayo Clin Proc. 1993 Sep;68(9):874-9 [8396700.001]

[Cites] Cancer. 1994 Jun 15;73(12):2922-9 [8199989.001]

[Cites] Lancet. 1994 Dec 17;344(8938):1655-60 [7996958.001]

[Cites] Ann Surg. 1996 Apr;223(4):384-94 [8633917.001]

[Cites] Br J Surg. 1996 Apr;83(4):478-81 [8665234.001]

[Cites] Eur J Surg Oncol. 1996 Aug;22(4):366-71 [8783654.001]

[Cites] Ann Oncol. 1996 Aug;7(6):593-600 [8879373.001]

[Cites] Cancer. 1997 Mar 1;79(5):892-9 [9041150.001]

[Cites] Gastrointest Endosc. 1997 Mar;45(3):251-60 [9087831.001]

[Cites] Hepatogastroenterology. 1997 Sep-Oct;44(17):1477-83 [9356876.001]

[Cites] Gastroenterologist. 1997 Dec;5(4):306-15 [9436006.001]

[Cites] AJR Am J Roentgenol. 1998 Feb;170(2):403-8 [9456954.001]

[Cites] Ann Surg. 1998 Mar;227(3):405-11 [9527064.001]

[Cites] Endoscopy. 1989 Dec;21 Suppl 1:351-6 [2606085.001]

[Cites] Semin Liver Dis. 1990 May;10(2):131-41 [2162565.001]

[Cites] World J Surg. 1990 Jul-Aug;14(4):535-43; discussion 544 [2166381.001]

[Cites] Surg Clin North Am. 1990 Dec;70(6):1429-47 [2174191.001]

[Cites] Br J Surg. 2000 Jan;87(1):110-5 [10606921.001]

[Cites] Am J Gastroenterol. 2000 Jan;95(1):204-7 [10638584.001]

[Cites] Gut. 2000 Feb;46(2):250-4 [10644321.001]

[Cites] Br J Surg. 2000 Apr;87(4):418-22 [10759735.001]

[Cites] Curr Gastroenterol Rep. 1999 Apr;1(2):95-101 [10980934.001]

[Cites] J Hepatobiliary Pancreat Surg. 2000;7(2):122-7 [10982603.001]

[Cites] J Hepatobiliary Pancreat Surg. 2000;7(2):135-41 [10982605.001]

[Cites] Ann Surg. 2001 Mar;233(3):385-92 [11224627.001]

[Cites] Am J Surg. 2001 Jan;181(1):52-9; discussion 87 [11248177.001]

[Cites] Am J Surg. 2001 Jan;181(1):65-70 [11248179.001]

[Cites] J Hepatobiliary Pancreat Surg. 2001;8(1):58-64 [11294291.001]

[Cites] J Am Coll Surg. 2001 Jun;192(6):726-34 [11400966.001]

[Cites] Ann Surg. 2001 Jul;234(1):47-55 [11420482.001]

[Cites] Radiology. 2001 Jul;220(1):90-6 [11425978.001]

[Cites] World J Surg. 2001 Oct;25(10):1277-83 [11596890.001]

[Cites] Radiographics. 2002 Jan-Feb;22(1):173-87 [11796906.001]

[Cites] Br J Surg. 2002 Feb;89(2):179-84 [11856130.001]

[Cites] Ann Surg. 2002 Mar;235(3):392-9 [11882761.001]

[Cites] J Comput Assist Tomogr. 2002 May-Jun;26(3):405-10 [12016370.001]

[Cites] Eur Radiol. 2002 Aug;12(8):1993-9 [12136317.001]

[Cites] Br J Surg. 2002 Oct;89(10):1260-7 [12296893.001]

[Cites] Gut. 2002 Nov;51 Suppl 6:VI1-9 [12376491.001]

[Cites] J Magn Reson Imaging. 2002 Dec;16(6):676-84 [12451581.001]

[Cites] Gastrointest Endosc. 2003 Feb;57(2):178-82 [12556780.001]

[Cites] Ann Surg. 2003 Feb;237(2):208-17 [12560779.001]

[Cites] Lancet Oncol. 2003 Mar;4(3):167-76 [12623362.001]

[Cites] Ann Surg. 2003 Jul;238(1):73-83 [12832968.001]

[Cites] Ann Surg. 2003 Jul;238(1):84-92 [12832969.001]

[Cites] Arch Surg. 1998 Jul;133(7):735-9 [9688001.001]

[Cites] Gastrointest Endosc. 1998 Oct;48(4):406-10 [9786115.001]

[Cites] Ann Surg. 1999 Jan;229(1):76-83 [9923803.001]

[Cites] Hepatogastroenterology. 1998 Nov-Dec;45(24):2020-6 [9951857.001]

[Cites] Gastrointest Endosc. 1999 Mar;49(3 Pt 1):349-57 [10049419.001]

[Cites] Arch Surg. 1999 May;134(5):526-32 [10323425.001]

[Cites] N Engl J Med. 1999 Jul 22;341(4):258-64 [10413739.001]

[Cites] Hepatogastroenterology. 1999 May-Jun;46(27):1585-91 [10430299.001]

[Cites] Ann Surg. 1999 Aug;230(2):131-42 [10450725.001]

[Cites] N Engl J Med. 1999 Oct 28;341(18):1368-78 [10536130.001]

[Cites] Ann Surg. 2005 Jan;241(1):77-84 [15621994.001]

[Cites] Am J Clin Oncol. 2005 Feb;28(1):21-3 [15685030.001]

[Cites] Hepatogastroenterology. 2005 Jan-Feb;52(61):5-7 [15782981.001]

[Cites] Ann Surg. 2005 May;241(5):693-9; discussion 699-702 [15849505.001]

[Cites] Gastrointest Endosc. 2005 Sep;62(3):374-82 [16111955.001]

[Cites] Lancet. 2005 Oct 8;366(9493):1303-14 [16214602.001]

[Cites] Am J Gastroenterol. 2005 Nov;100(11):2426-30 [16279895.001]

[Cites] J Am Coll Surg. 2006 Jan;202(1):87-92 [16377501.001]

[Cites] J Clin Gastroenterol. 2006 Feb;40(2):162-6 [16394879.001]

[Cites] Cancer Chemother Pharmacol. 2006 May;57(5):647-53 [16142487.001]

[Cites] Ann Surg. 2006 Mar;243(3):364-72 [16495702.001]

[Cites] AJR Am J Roentgenol. 2006 Jun;186(6):1580-6 [16714646.001]

[Cites] Ann Surg. 2006 Aug;244(2):240-7 [16858186.001]

[Cites] Am Surg. 2006 Jul;72(7):599-604; discussion 604-5 [16875081.001]

[Cites] Surgery. 2007 May;141(5):581-8 [17462457.001]

[Cites] J Hepatobiliary Pancreat Surg. 2007;14(4):351-7 [17653632.001]

[Cites] Gastrointest Endosc. 2007 Oct;66(4):730-6 [17905015.001]

[Cites] J Hepatobiliary Pancreat Surg. 2008;15(1):2-6 [18274838.001]

[Cites] Oncology. 2004;66(2):138-42 [15138366.001]

[Cites] Ann Surg. 2004 Jul;240(1):95-101 [15213624.001]

[Cites] J Hepatobiliary Pancreat Surg. 2004;11(4):239-44 [15368107.001]

[Cites] Radiology. 2004 Oct;233(1):234-40 [15333766.001]

(PMID = 18274839.001).

[ISSN] 0944-1166

[Journal-full-title] Journal of hepato-biliary-pancreatic surgery

[ISO-abbreviation] J Hepatobiliary Pancreat Surg

[Language] eng

[Publication-type] Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't

[Publication-country] Japan

[Other-IDs] NLM/ PMC2794355

[Investigator] Kai M; Kimura Y; Kai S; Kimura Y; Sawada S; Shimizu H; Nakagawara H; Nakachi K; Yoshitome H; Saisyo H; Shikata S; Nimura Y

   

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[Title] [Second-look operation in pancreatic carcinoma previously assessed as unresectable].

BACKGROUND: The only curative therapy for patients with pancreatic carcinoma consists of -complete surgical tumour removal.

PATIENTS AND METHODS: We report herein on 17 patients who were judged during exploratory laparotomy elsewhere to suffer from non-resectable pancreatic cancer and who underwent a second-look operation after referral to our hospital.

The classic Kausch-Whipple operation was performed in 4, pylorus-preserving pancreaticoduodenectomy in 5, and left pancreatic -resection in another 4 patients.

Mean survival in patients after tumour resection was increased, reach-ing 17.6 months compared to 6.5 months in patients with non-resectable pancreatic cancer.

Thus, complex visceral operations like pancreatic carcinoma resection should preferably be performed in high-volume centres exclusively.

[MeSH-major] Ampulla of Vater / surgery. Carcinoma, Pancreatic Ductal / surgery. Common Bile Duct Neoplasms / surgery. Pancreatic Neoplasms / surgery

[MeSH-minor] Academic Medical Centers. Adult. Aged. Disease Progression. Female. Follow-Up Studies. Germany. Hospitals, General / statistics & numerical data. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Palliative Care. Pancreas / pathology. Pancreas / surgery. Prognosis. Referral and Consultation / statistics & numerical data. Reoperation / statistics & numerical data. Survival Rate. Tomography, X-Ray Computed

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[Copyright] Georg Thieme Verlag Stuttgart, New York.

(PMID = 20162503.001).

[ISSN] 1438-9592

[Journal-full-title] Zentralblatt für Chirurgie

[ISO-abbreviation] Zentralbl Chir

[Language] ger

[Publication-type] English Abstract; Journal Article

[Publication-country] Germany

   

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[Title] Periampullary carcinoid of the ampulla of Vater presenting as an intraductal papillary mucinous tumour of the pancreas: a sheep in wolf's clothing.

[MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Ampulla of Vater. Carcinoma, Pancreatic Ductal / diagnosis. Common Bile Duct Neoplasms / diagnosis

[MeSH-minor] Dilatation, Pathologic. Humans. Immunohistochemistry. Male. Middle Aged. Pancreatectomy. Pancreatic Ducts / pathology. Pancreatic Ducts / radiography. Tomography, X-Ray Computed

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[Cites] J Gastrointest Surg. 2003 Sep-Oct;7(6):773-6 [13129555.001]

[Cites] N Engl J Med. 1999 Mar 18;340(11):858-68 [10080850.001]

[Cites] Hong Kong Med J. 2005 Jun;11(3):213-5 [15951589.001]

[Cites] J Gastroenterol Hepatol. 2005 May;20(5):676-81 [15853978.001]

[Cites] Cancer. 1999 Mar 15;85(6):1241-9 [10189128.001]

(PMID = 18682788.001).

[ISSN] 1488-2310

[Journal-full-title] Canadian journal of surgery. Journal canadien de chirurgie

[ISO-abbreviation] Can J Surg

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Canada

[Other-IDs] NLM/ PMC2496582

   

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[Title] Carcinoma arising from villous adenoma of the ampullary bile duct: Report of a case.

Adenocarcinoma arising from the villous adenoma of the ampullary biliary epithelium is an extremely rare disorder.

The preoperative diagnosis and treatment of the disease represent a major difficulty.

Next, a transduodenal resection of ampulla and reconstruction were performed.

This case shows the importance of surgeons to keep in mind the fact that frozen examinations may sometimes miss a malignancy and they therefore cannot be relied upon to rule out malignancy in villous adenoma of the ampullary bile duct.

[MeSH-major] Adenocarcinoma / diagnosis. Adenoma, Villous / diagnosis. Ampulla of Vater. Common Bile Duct Neoplasms / diagnosis. Neoplasms, Multiple Primary

[MeSH-minor] Aged. Cholangiopancreatography, Endoscopic Retrograde. Cholecystectomy. Diagnosis, Differential. Duodenoscopy. Female. Follow-Up Studies. Humans

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[Cites] Arch Surg. 1996 Apr;131(4):366-71 [8615720.001]

[Cites] Ann Surg. 1997 May;225(5):590-9; discussion 599-600 [9193186.001]

[Cites] Arch Surg. 1988 Jan;123(1):96 [3337662.001]

[Cites] Hepatogastroenterology. 1999 May-Jun;46(27):1959-62 [10430377.001]

[Cites] Langenbecks Arch Surg. 1998 Apr;383(2):190-3 [9641898.001]

[Cites] Ann Surg. 1998 Jul;228(1):87-94 [9671071.001]

[Cites] Br J Surg. 1997 Jul;84(7):948-51 [9240132.001]

[Cites] HPB Surg. 1999;11(3):191-3 [10371065.001]

[Cites] Cancer. 1989 Jul 1;64(1):161-7 [2471581.001]

[Cites] South Med J. 1989 Jul;82(7):917-20 [2665132.001]

[Cites] Arch Surg. 1993 May;128(5):515-20 [8098205.001]

[Cites] AJR Am J Roentgenol. 1990 Jun;154(6):1217-8 [2110730.001]

[Cites] Yonsei Med J. 1999 Feb;40(1):84-9 [10198612.001]

[Cites] Am Surg. 1990 Apr;56(4):214-7 [2194412.001]

[Cites] Surgery. 2000 Jun;127(6):628-33 [10840357.001]

[Cites] Ann Surg. 1988 Mar;207(3):234-9 [3345110.001]

[Cites] Arch Surg. 1999 May;134(5):526-32 [10323425.001]

[Cites] Gastrointest Endosc. 1990 Nov-Dec;36(6):588-92 [2279648.001]

[Cites] Langenbecks Arch Surg. 2001 Apr;386(3):172-5 [11382317.001]

(PMID = 17243040.001).

[ISSN] 0941-1291

[Journal-full-title] Surgery today

[ISO-abbreviation] Surg. Today

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Japan

   

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[Title] Unusual histological findings after partial pancreaticoduodenectomy including benign multicystic mesothelioma, adenomyoma of the ampulla of Vater, and undifferentiated carcinoma, sarcomatoid variant: a case series.

INTRODUCTION: The standard operation for carcinoma of the pancreatic head is a partial pancreaticoduodenectomy.

Histology showed an adenomyoma of the ampulla.

Pathology showed an undifferentiated carcinoma, sarcomatoid variant.

Adenomyoma of the bile duct or ampullary region is a very unusual, benign, localized lesion characterized by adenomyomatous hyperplasia.

Undifferentiated carcinoma, sarcomatoid variant, is an aggressive tumor and is characterized by spindle cells.

As the lesions were suspicious for carcinoma, partial pancreaticoduodenectomy was justified in all three patients.

The histologic diagnosis after partial pancreaticoduodenectomy may differ from the preoperative and intraoperative findings.

These cases demonstrate that a definitive diagnosis may only be obtained by a pathologic examination of the surgical specimen.

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[Cites] Surg Today. 2000;30(1):98-100 [10648095.001]

[Cites] Hum Pathol. 2003 Apr;34(4):369-74 [12733118.001]

[Cites] Mod Pathol. 2003 Jun;16(6):530-6 [12808057.001]

[Cites] Surg Today. 2008;38(1):85-9 [18085373.001]

[Cites] Cancer. 1989 Sep 15;64(6):1336-46 [2766227.001]

[Cites] Pancreas. 2005 Oct;31(3):291-2 [16163064.001]

[Cites] J Gastroenterol. 1995 Aug;30(4):547-50 [7550871.001]

[Cites] Ann Surg. 1990 Apr;211(4):447-58 [2322039.001]

[Cites] Cancer. 1979 Aug;44(2):692-8 [476578.001]

[Cites] Surg Gynecol Obstet. 1978 Jun;146(6):959-62 [653575.001]

[Cites] Am J Obstet Gynecol. 1983 Feb 1;145(3):355-9 [6824025.001]

[Cites] Cancer. 1982 Oct 15;50(8):1615-22 [7116294.001]

[Cites] Ann Surg. 1935 Oct;102(4):763-79 [17856666.001]

(PMID = 21143956.001).

[ISSN] 1752-1947

[Journal-full-title] Journal of medical case reports

[ISO-abbreviation] J Med Case Rep

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Other-IDs] NLM/ PMC3016302

   

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[Title] Therapeutic approach to tumors of the ampulla of Vater.

BACKGROUND/AIM: Indications for local resection for tumors of the ampulla of Vater have not been established.

The present study evaluated suitable treatments for tumors of the papilla of Vater.

PATIENTS AND METHODS: Clinicopathological factors were reviewed for 53 patients with tumors of the ampulla of Vater treated between February 1993 and August 2003.

Lymph node metastasis was identified in 20 patients who received radical resection, including 1 patient with pT1 cancer.

CONCLUSION: Given the presence of some positive surgical margins, local resection is indicated as a therapeutic approach to tumors of the papilla of Vater only for benign tumors or some malignant tumors that cannot undergo pancreaticoduodenectomy (PD).

[MeSH-major] Adenoma / surgery. Ampulla of Vater. Carcinoma / surgery. Common Bile Duct Neoplasms / surgery. Digestive System Surgical Procedures / methods

[MeSH-minor] Adult. Aged. Biopsy. Cholangiopancreatography, Endoscopic Retrograde. Diagnosis, Differential. Endosonography. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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(PMID = 16860623.001).

[ISSN] 0002-9610

[Journal-full-title] American journal of surgery

[ISO-abbreviation] Am. J. Surg.

[Language] eng

[Publication-type] Comparative Study; Journal Article

[Publication-country] United States

   

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[Title] Ampullary carcinoma: effect of preoperative biliary drainage on surgical outcome.

AIM: To evaluate the influence of preoperative biliary drainage on morbidity and mortality after surgical resection for ampullary carcinoma.

METHODS: We analyzed retrospectively data for 82 patients who underwent potentially curative surgery for ampullary carcinoma between September 1993 and July 2007 at the Singapore General Hospital, a tertiary referral hospital.

Diagnosis of ampullary carcinoma was confirmed histologically.

The following parameters were analyzed: wound infection, intra-abdominal abscess, intra-abdominal or gastrointestinal bleeding, septicemia, biliary or pancreatic leakage, pancreatitis, gastroparesis, and re-operation rate.

However, the rest of the parameters did not differ significantly between the groups, i.e. sepsis [10 (28.6%) vs 14 (29.8%)], intra-abdominal bleeding [1 (2.9%) vs 5 (10.6%)], intra-abdominal abscess [1 (2.9%) vs 8 (17%)], gastrointestinal bleeding [3 (8.6%) vs 5 (10.6%)], pancreatic leakage [2 (5.7%) vs 3 (6.4%)], biliary leakage [2 (5.7%) vs 3 (6.4%)], pancreatitis [2 (5.7%) vs 2 (4.3%)], gastroparesis [6 (17.1%) vs 10 (21.3%)], need for blood transfusion [10 (28.6%) vs 17 (36.2%)] and re-operation rate [1 (2.9%) vs 5 (10.6%)].

CONCLUSION: Biliary drainage before surgery for ampullary cancer significantly reduced postoperative wound infection.

[MeSH-major] Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Drainage. Pancreatic Neoplasms / surgery. Preoperative Care

MedlinePlus Health Information. consumer health - Pancreatic Cancer.

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[Cites] HPB Surg. 2000;11(5):311-8 [10674746.001]

[Cites] Br J Surg. 1994 Aug;81(8):1195-8 [7741850.001]

[Cites] J Gastroenterol Hepatol. 2004 Sep;19(9):994-7 [15304115.001]

[Cites] Br J Surg. 1978 Jul;65(7):521-2 [667551.001]

[Cites] Arch Surg. 1984 Jun;119(6):703-8 [6428380.001]

[Cites] Am J Surg. 1986 Apr;151(4):476-9 [3515981.001]

[Cites] Arch Surg. 1987 Jun;122(6):731-4 [3579589.001]

[Cites] Ann Surg. 1988 Jan;207(1):39-47 [3276272.001]

[Cites] Acta Chir Scand. 1987 Nov-Dec;153(11-12):665-8 [3434110.001]

[Cites] Am J Infect Control. 1988 Feb;16(1):3-6 [3369746.001]

[Cites] Gut. 1989 Aug;30(8):1132-5 [2475392.001]

[Cites] Br J Surg. 1990 Apr;77(4):440-2 [2160307.001]

[Cites] Ann Surg. 1990 Aug;212(2):221-7 [2375652.001]

[Cites] Lancet. 1994 Dec 17;344(8938):1655-60 [7996958.001]

[Cites] Ann Surg. 1999 Aug;230(2):131-42 [10450725.001]

[Cites] J Gastrointest Surg. 1999 Sep-Oct;3(5):496-505 [10482706.001]

[Cites] Surgery. 2007 Sep;142(3):313-8 [17723881.001]

[Cites] World J Gastroenterol. 2008 Feb 21;14(7):1102-7 [18286694.001]

[Cites] Ann Surg Oncol. 2008 Nov;15(11):3138-46 [18787902.001]

[Cites] Br J Surg. 1990 Nov;77(11):1229-32 [2253000.001]

[Cites] Br J Surg. 1991 May;78(5):568-71 [2059808.001]

[Cites] Surgery. 1992 May;111(5):562-8 [1598676.001]

[Cites] J Gastrointest Surg. 2000 May-Jun;4(3):258-67; discussion 267-8 [10769088.001]

(PMID = 19533815.001).

[ISSN] 2219-2840

[Journal-full-title] World journal of gastroenterology

[ISO-abbreviation] World J. Gastroenterol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] China

[Other-IDs] NLM/ PMC2699011