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1. Afolabi OC, Odukoya O, Arole G, Banjo AF: Evaluation of nucleolar organizer regions in tumours of the jaw bones. Niger Postgrad Med J; 2001 Mar;8(1):7-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Silver stained nucleolar proteins (AgNORs) were counted in a variety of jaw bone tumours.
  • Malignant bone tumour cells possessed more than five small AgNORs (5.54 +/- 0.44).
  • The number ofAgNORs in recurrent osteosarcoma, recurrent ameloblastic carcinoma and recurrent chondrosarcoma was much higher than in their respective primary lesion but without statistical significant difference.
  • [MeSH-minor] Ameloblastoma / genetics. Ameloblastoma / pathology. Antineoplastic Agents / pharmacology. Antineoplastic Agents / therapeutic use. Case-Control Studies. Chondrosarcoma / genetics. Chondrosarcoma / pathology. Diagnosis, Differential. Humans. Osteosarcoma / drug therapy. Osteosarcoma / genetics. Osteosarcoma / pathology. Silver Staining

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  • (PMID = 11487776.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor
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2. Vered M, Shohat I, Buchner A, Dayan D: Myofibroblasts in stroma of odontogenic cysts and tumors can contribute to variations in the biological behavior of lesions. Oral Oncol; 2005 Nov;41(10):1028-33
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  • [Title] Myofibroblasts in stroma of odontogenic cysts and tumors can contribute to variations in the biological behavior of lesions.
  • Stromal myofibroblasts (MF) have the potential to facilitate progression of neoplastic epithelial lesions that could contribute to their biological behavior.
  • To assess immunohistochemically the frequency of stromal MF in different odontogenic cysts and tumors and correlate it to their aggressive biological behavior.
  • The study included cases of dentigerous cyst (DC, n = 7), odontogenic keratocyst-parakeratinized type (OKC-P, n = 8), orthokeratinized type (OKC-O, n = 9), ameloblastic fibroma/fibro-odontoma (AMF/O, n = 11), unicystic ameloblastoma (UAM, n = 6), and solid ameloblastoma (SAM, n = 7).
  • Cases of oral squamous cell carcinoma (SCC, n = 5) served as control.
  • The high frequency of stromal MF in known aggressive odontogenic lesions, such as OKC-P and SAM, implies that MF can contribute to the biological behavior of these odontogenic lesions.
  • Various pharmacological agents that control stromal MF can be used as an aid to reduce extensive and mutilating surgery in cases of remarkably aggressive odontogenic lesions.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Fibroblasts / ultrastructure. Maxillary Diseases / pathology. Odontogenic Cysts / pathology. Odontogenic Tumors / pathology. Odontoma / pathology

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  • (PMID = 16139563.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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