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Items 1 to 41 of about 41
1. Kamath KP, Vidya M, Shetty N, Karkera BV, Jogi H: Nucleolar organizing regions and alpha-smooth muscle actin expression in a case of ameloblastic carcinoma. Head Neck Pathol; 2010 Jun;4(2):157-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nucleolar organizing regions and alpha-smooth muscle actin expression in a case of ameloblastic carcinoma.
  • Ameloblastic carcinoma is a rare lesion of odontogenic origin.
  • It is defined as a malignant epithelial odontogenic tumor that histologically has retained the features of ameloblastic differentiation and also exhibits cytologic features of malignancy, like atypia and mitotic activity.
  • In this case study reporting a case of ameloblastic carcinoma, we have attempted to verify the previous findings on the use of Argyrophilic nucleolar organizing regions (AgNORs) and immunohistochemical staining for the alpha-smooth muscle actin (alpha-SMA) in differentiating ameloblastic carcinoma from ameloblastoma.
  • It was observed that AgNORs was found to be almost twice in ameloblastic carcinoma as it was in ameloblastoma.
  • A difference between the two lesions in the pattern of expression of alpha-SMA was also observed, with alpha-SMA being expressed in the odontogenic epithelium and the stroma of ameloblastic carcinoma whereas, in the case of ameloblastoma, it was found only in the stromal part.
  • These findings suggest that AgNORs and alpha-SMA expression may be used as adjuncts to the routine histopathologic examination to differentiate ameloblastic carcinoma and ameloblastoma.
  • [MeSH-major] Actins / metabolism. Ameloblastoma / pathology. Carcinoma / pathology. Mandibular Neoplasms / pathology. Nucleolus Organizer Region / pathology

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  • (PMID = 20333560.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Antigens, Nuclear; 0 / Biomarkers, Tumor; 0 / nucleolar organizer region associated proteins
  • [Other-IDs] NLM/ PMC2878627
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2. Immerman SB, Morris LG, DeLacure MD, Wang BY, Kurago Z: Pathology quiz case 1: ameloblastic carcinoma. Arch Otolaryngol Head Neck Surg; 2010 Jun;136(6):634, 636
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathology quiz case 1: ameloblastic carcinoma.

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  • (PMID = 20578291.001).
  • [ISSN] 1538-361X
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA009685-10; United States / NCI NIH HHS / CA / T32 CA009685; United States / NCI NIH HHS / CA / T32 CA009685-10
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS255349; NLM/ PMC3014859
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3. Devenney-Cakir B, Dunfee B, Subramaniam R, Sundararajan D, Mehra P, Spiegel J, Sakai O: Ameloblastic carcinoma of the mandible with metastasis to the skull and lung: advanced imaging appearance including computed tomography, magnetic resonance imaging and positron emission tomography computed tomography. Dentomaxillofac Radiol; 2010 Oct;39(7):449-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma of the mandible with metastasis to the skull and lung: advanced imaging appearance including computed tomography, magnetic resonance imaging and positron emission tomography computed tomography.
  • Ameloblastic carcinoma is a very rare malignant odontogenic tumour with characteristic histopathological and clinical features, which requires aggressive surgical treatment and surveillance and, therefore, differs from ameloblastoma.
  • We describe a case of ameloblastic carcinoma with metastasis to the skull and lung with emphasis on imaging features including MRI and PET-CT.

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  • (PMID = 20841465.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Other-IDs] NLM/ PMC3520182
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4. Ram H, Mohammad S, Husain N, Gupta PN: Ameloblastic carcinoma. J Maxillofac Oral Surg; 2010 Dec;9(4):415-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma.
  • Ameloblastic carcinoma (AC) is a rare aggressive malignant epithelial odontogenic tumor of the maxillofacial skeleton with a distinct predilection in the mandible.
  • It exhibits cytological features of ameloblastoma and carcinoma.
  • The clinical course of ameloblastic carcinoma is typically aggressive, with extensive local destruction.
  • Radiotherapy and chemotherapy have limited role in the treatment of ameloblastic carcinomas.

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  • (PMID = 22190836.001).
  • [ISSN] 0974-942X
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3177477
  • [Keywords] NOTNLM ; Ameloblastic carcinoma / Ameloblastoma / Odontogenic tumor
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5. Hall JM, Weathers DR, Unni KK: Ameloblastic carcinoma: an analysis of 14 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Jun;103(6):799-807
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma: an analysis of 14 cases.
  • OBJECTIVES: To present the classifications of malignant ameloblastomas, provide histopathologic guidelines for the diagnosis of ameloblastic carcinoma, and discuss treatment and long-term follow-up.
  • STUDY DESIGN: Fourteen archival specimens of ameloblastic carcinoma with detailed treatment and follow-up documentation were identified by the authors.
  • Histopathologic features of ameloblastic carcinoma include lack of differentiation, hypercellularity, high mitotic index, vascular invasion, and neural invasion.

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  • (PMID = 17448710.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Jeremic JV, Nikolic ZS, Boricic IV, Tacevic ZD, Tomanovic NR, Drcic LJ, Novkovic MD: Total mandibular reconstruction after resection of rare "honeycomb-like" ameloblastic carcinoma--a case report. J Craniomaxillofac Surg; 2010 Sep;38(6):465-8
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  • [Title] Total mandibular reconstruction after resection of rare "honeycomb-like" ameloblastic carcinoma--a case report.
  • PURPOSE: This case report describes a rare and aggressive ameloblastic carcinoma that infiltrated the mandible in a "honeycomb" pattern.
  • CONCLUSION: Ameloblastic carcinoma is a highly malignant lesion, which requires aggressive therapy.
  • Further reporting of ameloblastic carcinoma is encouraged.

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  • [Copyright] Copyright 2009 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 19945885.001).
  • [ISSN] 1878-4119
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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7. Bello IO, Alanen K, Slootweg PJ, Salo T: Alpha-smooth muscle actin within epithelial islands is predictive of ameloblastic carcinoma. Oral Oncol; 2009 Sep;45(9):760-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Alpha-smooth muscle actin within epithelial islands is predictive of ameloblastic carcinoma.
  • Ameloblastic carcinoma is a malignant tumor having features of ameloblastoma in addition to cytologic atypia with or without metastasis.
  • The aim of this study was to examine which epithelial and stromal markers are predictive of histologically diagnosed ameloblastic carcinoma and can sufficiently differentiate it from solid/multicystic ameloblastoma (SA).
  • We examined immunohistochemically Ki-67, epithelial membrane antigen (EMA), alpha-smooth muscle actin (alpha-SMA), calponin, p63 and DNA content using image (ICM) and flow cytometry (FCM) in three ameloblastic carcinomas and up to 18 SAs.
  • The important findings were that Ki-67 labeling index was significantly higher in ameloblastic carcinoma than SA while EMA, calponin, p63, ICM and FCM did not sufficiently differentiate the two groups of lesions.
  • Expression of alpha-SMA was consistently obtained within the epithelial island cells of ameloblastic carcinoma and not in SA, although the marker was well expressed in the stroma of both lesions.
  • We therefore conclude that the presence of alpha-SMA within the epithelial islands is highly predictive of ameloblastic carcinoma.
  • [MeSH-major] Ameloblastoma / pathology. Carcinoma / pathology. Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Neoplasm Proteins / metabolism

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  • (PMID = 19150605.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / CKAP4 protein, human; 0 / Calcium-Binding Proteins; 0 / Ki-67 Antigen; 0 / Membrane Proteins; 0 / Microfilament Proteins; 0 / Mucin-1; 0 / Neoplasm Proteins; 0 / calponin
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8. Roy Chowdhury SK, Ramen S, Chattopadhyay PK, Moorchung N, Rajkumar K: Ameloblastic Carcinoma of the mandible. J Maxillofac Oral Surg; 2010 Jun;9(2):198-201

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic Carcinoma of the mandible.
  • Odontogenic carcinomas are rare lesions arising from dental embryogenic residues and have been designated by a variety of terms like malignant ameloblastoma, ameloblastic carcinoma, metastatic ameloblastoma or primary intra-alveolar epidermoid carcinoma.
  • Ameloblastic carcinoma combines the histological features of ameloblastoma with cytological atypia, even in the absence of metastasis.
  • Majority originate de novo and the remaining are malignant transformation of an ameloblastoma.

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  • (PMID = 22190787.001).
  • [ISSN] 0974-942X
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3244098
  • [Keywords] NOTNLM ; Ameloblastic carcinoma / Odontogenic malignancies
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9. Jiménez MA, Castejón A, San Román F, Castaño M, Rodríguez-Bertos A: Maxillary ameloblastic carcinoma in an Alaskan Malamute. Vet Pathol; 2007 Jan;44(1):84-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Maxillary ameloblastic carcinoma in an Alaskan Malamute.
  • The tumor was diagnosed as an ameloblastic carcinoma because of the histologic signs of malignancy, the aggressive behavior, and the absence of distal metastasis.
  • This is the first description of an ameloblastic carcinoma in a dog.

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  • (PMID = 17197628.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Uzüm N, Akyol G, Asal K, Köybaşioğlu A: Ameloblastic carcinoma containing melanocyte and melanin pigment in the mandible: a case report and review of the literature. J Oral Pathol Med; 2005 Nov;34(10):618-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma containing melanocyte and melanin pigment in the mandible: a case report and review of the literature.
  • A case of ameloblastic carcinoma containing melanocyte and melanin in a 66-year-old male with swelling and an ulcerating firm mass in the left submandibular region is presented.

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  • (PMID = 16202083.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Melanins
  • [Number-of-references] 6
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11. Lucca M, D'Innocenzo R, Kraus JA, Gagari E, Hall J, Shastri K: Ameloblastic carcinoma of the maxilla: a report of 2 cases. J Oral Maxillofac Surg; 2010 Oct;68(10):2564-9
Genetic Alliance. consumer health - Ameloblastic carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma of the maxilla: a report of 2 cases.

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  • (PMID = 20678838.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Akrish S, Buchner A, Shoshani Y, Vered M, Dayan D: Ameloblastic carcinoma: report of a new case, literature review, and comparison to ameloblastoma. J Oral Maxillofac Surg; 2007 Apr;65(4):777-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma: report of a new case, literature review, and comparison to ameloblastoma.

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  • (PMID = 17368379.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 30
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13. Ward BB, Edlund S, Sciubba J, Helman JI: Ameloblastic carcinoma (primary type) isolated to the anterior maxilla: case report with review of the literature. J Oral Maxillofac Surg; 2007 Sep;65(9):1800-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma (primary type) isolated to the anterior maxilla: case report with review of the literature.

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  • (PMID = 17719401.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 8
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14. Abiko Y, Nagayasu H, Takeshima M, Yamazaki M, Nishimura M, Kusano K, Kitajo H, Saitoh M, Kawakami T, Chiba I, Kaku T: Ameloblastic carcinoma ex ameloblastoma: report of a case-possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Jan;103(1):72-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma ex ameloblastoma: report of a case-possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation.
  • Ameloblastic carcinoma is described in the updated World Health Organization (WHO) classification as a rare malignant lesion.
  • Ameloblastic carcinoma meeting the WHO criteria may arise either as a result of malignant change in a pre-existing benign ameloblastoma (carcinoma ex ameloblastoma) or as a primary malignant ameloblastoma not preceded by an ordinary ameloblastoma (de novo carcinoma).
  • We report a case of ameloblastic carcinoma ex ameloblastoma and examine how this case underwent malignant transformation.
  • The DNA was extracted separately from benign and malignant areas in paraffin sections of the tumor.
  • Hypermethylation of CpG islands of the p16 gene was detected in the malignant parts of the tumor.
  • The results indicate that hypermethylation of p16 may have been involved in the malignant transformation of the ameloblastoma in the present case.

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  • (PMID = 17178497.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cadherins; 0 / DNA, Neoplasm; 0 / DNA-Binding Proteins; 0 / PDRG1 protein, human
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15. Bologna-Molina R, Mosqueda-Taylor A, Lopez-Corella E, de Almeida OP, Carrasco-Daza D, Farfán-Morales JE, Molina-Frechero N, Damián-Matsumura P: Comparative expression of syndecan-1 and Ki-67 in peripheral and desmoplastic ameloblastomas and ameloblastic carcinoma. Pathol Int; 2009 Apr;59(4):229-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparative expression of syndecan-1 and Ki-67 in peripheral and desmoplastic ameloblastomas and ameloblastic carcinoma.
  • The aims of the present study were to examine whether the pattern of syndecan-1 expression correlates with cellular proliferation index in desmoplastic ameloblastomas (DA), peripheral ameloblastomas (PA) and ameloblastic carcinomas (AC), and to compare with that previously reported for solid (SA) and unicystic (UA) variants of ameloblastoma.
  • [MeSH-major] Ameloblastoma / pathology. Carcinoma / pathology. Jaw Neoplasms / pathology. Ki-67 Antigen / biosynthesis. Syndecan-1 / biosynthesis

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  • (PMID = 19351365.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Syndecan-1
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16. Ismail SB, Zain RB, Yaacob HB, Abraham MT: Ameloblastic carcinoma (spindle cell variant). Pathology; 2009;41(3):292-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma (spindle cell variant).

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  • (PMID = 19291545.001).
  • [ISSN] 1465-3931
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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17. Coulibaly B, Le Hémon A, Sorbier C, George L, Blanc JL, Fernandez C: [Ameloblastic carcinoma: primary or secondary?]. Ann Pathol; 2009 Feb;29(1):28-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ameloblastic carcinoma: primary or secondary?].
  • Ameloblastic carcinoma is a rare neoplasm.
  • The first case report is rare and concerns a man with an ameloblastic carcinoma primary-type of the maxillary.
  • The second case concerns a woman with an ameloblastic carcinoma secondary-type developed on a preexisting follicular ameloblastoma of the mandible.
  • The prognosis of such carcinoma must remain guarded over an observation period of several years because of the proximity of the lesion to vital structures.

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  • (PMID = 19233091.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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18. Naik V, Kale AD: Ameloblastic carcinoma: a case report. Quintessence Int; 2007 Nov-Dec;38(10):873-9
Genetic Alliance. consumer health - Ameloblastic carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma: a case report.
  • Ameloblastic carcinoma is a rare malignant lesion with characteristic histologic features and behavior that dictate a more radical surgical approach than does a simple ameloblastoma.
  • Clinically, ameloblastic carcinoma is more aggressive than most typical ameloblastomas with extensive local destruction, perforation of the cortical plate, extension into surrounding soft tissues, numerous recurrent lesions, and metastasis, usually to cervical lymph nodes.
  • The radiographic appearance of ameloblastic carcinoma is consistent with that of ameloblastoma except for occasional presence of some focal radiopacities, apparently reflecting dystrophic calcification.
  • These identifying features of ameloblastic carcinoma must be known and recognized by dental practitioners.
  • A case of ameloblastic carcinoma of the maxilla in a 70-year-old man is reported.

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  • (PMID = 18197328.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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19. Yazici N, Karagöz B, Varan A, Yilmaz T, Oztürk A, Usubütün A, Büyükpamukçu M: Maxillary ameloblastic carcinoma in a child. Pediatr Blood Cancer; 2008 Jan;50(1):175-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Maxillary ameloblastic carcinoma in a child.
  • We report an extremely rare occurrence of ameloblastic carcinoma located in the maxilla of a pediatric patient.
  • Histopathological diagnosis was established with morphological features of both ameloblastoma and carcinoma.
  • [MeSH-major] Ameloblastoma. Carcinoma. Maxillary Neoplasms

  • Genetic Alliance. consumer health - Ameloblastic carcinoma.
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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 16652346.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Angiero F, Borloni R, Macchi M, Stefani M: Ameloblastic carcinoma of the maxillary sinus. Anticancer Res; 2008 Nov-Dec;28(6B):3847-54
Genetic Alliance. consumer health - Ameloblastic carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma of the maxillary sinus.
  • Ameloblastic carcinoma is a very rare malignant odontogenic neoplasm of the mandible and maxilla, accounting for some 66 reported cases.
  • Cellular features of malignancy in the surgical specimen confirmed the diagnosis of ameloblastic carcinoma.
  • This case of an aggressive ameloblastic carcinoma of the maxillary gingiva that presented with an unusual histological pattern illustrates that these tumors can create a diagnostic challenge that may require extensive surgical sampling and/or removal to establish the diagnosis.
  • Immunohistochemically analyzed expression of bcl-2 protein, cytokeratins CAM 5 and 6, and Ki-67/MIB-1 antigen serve to characterize the cyto-differentiation and cellular activity of ameloblastic carcinoma.

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  • (PMID = 19192639.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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21. Benlyazid A, Lacroix-Triki M, Aziza R, Gomez-Brouchet A, Guichard M, Sarini J: Ameloblastic carcinoma of the maxilla: case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Dec;104(6):e17-24
Genetic Alliance. consumer health - Ameloblastic carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma of the maxilla: case report and review of the literature.
  • MATERIAL AND METHODS: A case of ameloblastic carcinoma of the maxilla arising in a 90-year-old patient is presented along with a review of 65 other cases of the international literature.
  • CONCLUSION: Ameloblastic carcinoma is a rare entity of odontogenic tumors that exhibits malignant histologic features in the primary site.

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  • (PMID = 17942338.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 48
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22. Yoon HJ, Hong SP, Lee JI, Lee SS, Hong SD: Ameloblastic carcinoma: an analysis of 6 cases with review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Dec;108(6):904-13
Genetic Alliance. consumer health - Ameloblastic carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma: an analysis of 6 cases with review of the literature.
  • OBJECTIVES: The purpose of this study is to report 6 cases of ameloblastic carcinoma and to analyze all published cases regarding demographic features, clinical behavior, treatment, and prognosis.
  • STUDY DESIGN: We reviewed our 6 cases of ameloblastic carcinoma and 98 cases previously reported in the English literature.
  • Five cases arose de novo, whereas 1 case was secondary type of ameloblastic carcinoma.
  • Microscopically, our cases showed malignant cytologic features with some histologic features of ameloblastoma.
  • Malignant cytologic features included nuclear pleomorphism, hyperchromatism, and high mitotic activity (33.3%).
  • CONCLUSION: Metastasis from an ameloblastic carcinoma is significantly correlated with poor prognosis.
  • [MeSH-major] Ameloblastoma / pathology. Carcinoma / pathology. Jaw Neoplasms / pathology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 19800270.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 44
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23. Ozlugedik S, Ozcan M, Basturk O, Deren O, Kaptanoglu E, Adanali G, Unal A: Ameloblastic carcinoma arising from anterior skull base. Skull Base; 2005 Nov;15(4):269-72; discussion 273

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma arising from anterior skull base.
  • Ameloblastic carcinoma (AC) is an aggressive malignant epithelial odontogenic tumor.

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  • [Cites] Head Neck. 1998 Oct;20(7):654-9 [9744469.001]
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  • (PMID = 16648889.001).
  • [ISSN] 1531-5010
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1380266
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24. Nakano K, Siar CH, Tsujigiwa H, Nagatsuka H, Nagai N, Kawakami T: Notch signaling in benign and malignant ameloblastic neoplasms. Eur J Med Res; 2008 Oct 27;13(10):476-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Notch signaling in benign and malignant ameloblastic neoplasms.
  • BACKGROUND: In general, Notch is a representative signal which controls morphosis and differentiation of cells, but its role in human odontogenic neoplasms, especially in ameloblastoma and its malignant counterpart, ameloblastic carcinoma, is not known.
  • METHODS: We examined Notch1 peptide and its gene (mRNA) in an ameloblastoma (case 1: 27-year-old female, right mandibular tumor) and an ameloblastic carcinoma (case 2: 93-year-old female, right mandibular tumor), using immunohistochemistry (IHC) and in situ hybridization (ISH) techniques.
  • CONCLUSIONS: Notch signaling plays some role in cytological differentiation or acquisition of tissue specific characteristics in neoplastic cells of odontogenic neoplasms, including ameloblastoma and ameloblastic carcinoma.
  • Notch1 may also contribute to cell cycle arrest induced by Notch1 activation in ameloblastic carcinoma.

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  • (PMID = 19008176.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / NOTCH1 protein, human; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Receptor, Notch1
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25. Ndukwe KC, Adebiyi EK, Ugboko VI, Adeyemo WL, Ajayi FO, Ladeinde AL, Okojie VN, Ajike SO, Olasoji HO: Ameloblastic carcinoma: a multicenter Nigerian study. J Oral Maxillofac Surg; 2010 Sep;68(9):2111-4
Genetic Alliance. consumer health - Ameloblastic carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma: a multicenter Nigerian study.
  • PURPOSE: To obtain a national profile on the prevalence and management of ameloblastic carcinoma in Nigerians.
  • MATERIALS AND METHODS: Data were collected from the case files of patients with a histologic diagnosis of ameloblastic carcinoma from 4 tertiary referral centers in Nigeria from January 1980 to December 2008.
  • A majority of the cases (17) occurred de novo, and 3 patients presented with carcinoma ex-ameloblastoma.
  • CONCLUSION: Ameloblastic carcinoma is an uncommon malignancy.
  • [MeSH-major] Ameloblastoma / epidemiology. Carcinoma / epidemiology. Mandibular Neoplasms / epidemiology. Maxillary Neoplasms / epidemiology. Odontogenic Tumors / epidemiology

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  • [Copyright] Copyright 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20538397.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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26. Zhang B, Zhang J, Xu ZY, Xie HL: Expression of RECK and matrix metalloproteinase-2 in ameloblastoma. BMC Cancer; 2009;9:427

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Ameloblastoma is a frequent odontogenic benign tumor characterized by local invasiveness, high risk of recurrence and occasional metastasis and malignant transformation.
  • METHODS: Immunohistochemistry and reverse transcription-polymerase chain reaction (RT-PCR) were employed to detect the protein and mRNA expression of RECK and MMP-2 in keratocystic odontogenic tumor (KCOT), ameloblastoma and ameloblastic carcinoma.
  • RESULTS: RECK protein expression was significantly reduced in KCOT (87.5%), ameloblastoma (56.5%) and ameloblastic carcinoma (0%) (P < 0.01), and was significantly lower in recurrent ameloblastoma compared with primary ameloblastoma (P < 0.01), but did not differ by histological type of ameloblastoma.
  • MMP-2 protein expression was significantly higher in ameloblastoma and ameloblastic carcinoma compared with KCOT (P < 0.01).
  • RECK mRNA expression was significantly lower in ameloblastoma than in KCOT (P < 0.01), lower in recurrent ameloblastoma than in primary ameloblastoma, and was negative in ameloblastic carcinoma.
  • RECK may participate in the invasion, recurrence and malignant transformation of ameloblastoma by regulating MMP-2 at the post-transcriptional level.

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  • [Cites] Cell. 2001 Dec 14;107(6):789-800 [11747814.001]
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  • (PMID = 19995435.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / RECK protein, human; 0 / RNA, Messenger; EC 3.4.24.24 / Matrix Metalloproteinase 2
  • [Other-IDs] NLM/ PMC2794878
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27. Jindal C, Palaskar S, Kaur H, Shankari M: Low-grade spindle-cell ameloblastic carcinoma: report of an unusual case with immunohistochemical findings and review of the literature. Curr Oncol; 2010 Oct;17(5):52-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low-grade spindle-cell ameloblastic carcinoma: report of an unusual case with immunohistochemical findings and review of the literature.
  • Spindle-cell differentiation in ameloblastic carcinoma is a rare event.
  • Although reported by many authors, it was first described as a separate entity in 1999 by Slater under the heading "low-grade spindle-cell ameloblastic carcinoma."
  • Here, we report a case of low-grade spindle-cell ameloblastic carcinoma arising in pre-existing unicystic ameloblastoma.The patient, a 60-year-old Indian woman, had a large irregular swelling in the left mandibular region.
  • To our knowledge, 6 cases of spindle-cell ameloblastic carcinoma have been published to date, and this case appears to be the first reporting malignant transformation with spindle-cell differentiation in unicystic ameloblastoma.

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  • (PMID = 20975879.001).
  • [ISSN] 1718-7729
  • [Journal-full-title] Current oncology (Toronto, Ont.)
  • [ISO-abbreviation] Curr Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2949371
  • [Keywords] NOTNLM ; Spindle cells / ameloblastic carcinoma
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28. Karakida K, Aoki T, Sakamoto H, Takahashi M, Akamatsu T, Ogura G, Sekido Y, Ota Y: Ameloblastic carcinoma, secondary type: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Dec;110(6):e33-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma, secondary type: a case report.
  • Malignant variants of ameloblastoma include metastasizing ameloblastoma, which microscopically appears benign but has metastasized and ameloblastic carcinoma that exhibits malignant histopathologic features.
  • Ameloblastic carcinoma is classified into 2 types: a primary odontogenic malignancy and a secondary type resulting from malignant transformation of ameloblastoma.
  • Most secondary ameloblastic carcinomas result from malignant transformation of a primary lesion after repeated postsurgical recurrences.
  • Therefore it is rare to find an untreated secondary type presenting with histologic features of malignant transformation from an earlier benign lesion.
  • We experienced a rare case of ameloblastic carcinoma, secondary type which might arise in an untreated ameloblastoma.
  • The mechanism by which a preexisting benign ameloblastoma goes through a malignant transformation is also described.

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  • [Copyright] Crown Copyright © 2010. Published by Mosby, Inc. All rights reserved.
  • (PMID = 21112523.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53
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29. Reid-Nicholson M, Teague D, White B, Ramalingam P, Abdelsayed R: Fine needle aspiration findings in malignant ameloblastoma: a case report and differential diagnosis. Diagn Cytopathol; 2009 Aug;37(8):586-91

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration findings in malignant ameloblastoma: a case report and differential diagnosis.
  • We present a case of malignant ameloblastoma presenting in the posterior mandible and cervical lymph nodes of an African American child.
  • Adequate sampling is paramount to accurate diagnosis, and is especially important when attempting to distinguish ameloblastoma from ameloblastic carcinoma.

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  • (PMID = 19373909.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Ladeinde AL, Ogunlewe MO, Bamgbose BO, Adeyemo WL, Ajayi OF, Arotiba GT, Akinwande JA: Ameloblastoma: analysis of 207 cases in a Nigerian teaching hospital. Quintessence Int; 2006 Jan;37(1):69-74

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • One hundred and ninety-eight (95.7%) were benign, and 9 (4.3%) were malignant.
  • The average ages on presentation for ameloblastoma and ameloblastic carcinoma were 31.67 and 46.44 years, respectively.
  • Nine (4.3%) cases of ameloblastic carcinoma were also reported.

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  • (PMID = 16429706.001).
  • [ISSN] 0033-6572
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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31. Suomalainen A, Hietanen J, Robinson S, Peltola JS: Ameloblastic carcinoma of the mandible resembling odontogenic cyst in a panoramic radiograph. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 May;101(5):638-42
Genetic Alliance. consumer health - Ameloblastic carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastic carcinoma of the mandible resembling odontogenic cyst in a panoramic radiograph.
  • Ameloblastic carcinoma is a rare odontogenic tumor exhibiting histologic evidence of malignancy in the primary or recurrent tumor, regardless of whether it has metastasized or not.
  • Most ameloblastic carcinomas are presumed to have arisen de novo, with few cases of malignant transformation of ameloblastoma being apparent.
  • A case is reported of a 21-year-old caucasian female with ameloblastic carcinoma in the left angulus area of the mandible resembling an odontogenic cyst in the panoramic radiograph.

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  • (PMID = 16632277.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Kumamoto H, Ooya K: Immunohistochemical detection of uPA, uPAR, PAI-1, and maspin in ameloblastic tumors. J Oral Pathol Med; 2007 Sep;36(8):488-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical detection of uPA, uPAR, PAI-1, and maspin in ameloblastic tumors.
  • BACKGROUND: To evaluate the roles of extracellular matrix (ECM)-degrading serine proteinase in progression of odontogenic tumors, expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR), plasminogen activator inhibitor-1 (PAI-1), and maspin was analyzed in ameloblastic tumors as well as in tooth germs.
  • METHODS: Tissue specimens of 10 tooth germs, 45 ameloblastomas, and 5 malignant ameloblastic tumors were examined immunohistochemically with the use of antibodies against uPA, uPAR, PAI-1, and maspin.
  • The levels of uPA and uPAR immunoreactivity in ameloblastic tumors were slightly higher than the levels in tooth germs, while PAI-1 reactivity in ameloblastomas tended to be lower than that in tooth germs.
  • The level of maspin immunoreactivity in ameloblastomas was significantly higher than that in tooth germs, and ameloblastic carcinoma showed decreased maspin reactivity.
  • CONCLUSION: Expression of uPA, uPAR, PAI-1, and maspin in tooth germs and ameloblastic tumors suggests that interactions among these molecules contribute to ECM degradation and cell migration during tooth development and tumor progression.
  • Altered expression of the serine proteinase and its associated molecules in ameloblastic tumors may be involved in oncogenesis of odontogenic epithelium.

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  • (PMID = 17686008.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Enzyme Precursors; 0 / PLAUR protein, human; 0 / Plasminogen Activator Inhibitor 1; 0 / Receptors, Cell Surface; 0 / Receptors, Urokinase Plasminogen Activator; 0 / SERPIN-B5; 0 / Serine Proteinase Inhibitors; 0 / Serpins; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator
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33. Mukhopadhyay S, Raha K, Mondal SC: Huge ameloblastoma of jaw-A case report. Indian J Otolaryngol Head Neck Surg; 2005 Jul;57(3):247-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is a tumour of intermediate malignant potential which lies in the gray zone between benign and malignant neoplasm.
  • The cases showing distant metastasis are recognized as malignant ameloblastoma.
  • Ameloblastic carcinoma is a tumor with microscopic features of ameloblastoma that displays malignant features at cytological level.([2]) It usually has aggressive course.

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  • [Cites] Oral Surg Oral Med Oral Pathol. 1984 Feb;57(2):168-76 [6366686.001]
  • (PMID = 23120181.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3451340
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34. Jundt G, Reichart PA: [Malignant odontogenic tumors]. Pathologe; 2008 May;29(3):205-13

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant odontogenic tumors].
  • Malignant odontogenic tumors are extremely rare.
  • As with benign odontogenic tumors, malignant epithelial odontogenic tumors or odontogenic carcinomas are distinguished from the even rarer mesenchymal ones, the odontogenic sarcomas.
  • Odontogenic carcinomas comprise ameloblastic carcinoma (AmCa), primary intraosseous carcinoma (PIOC), clear cell odontogenic carcinoma, odontogenic ghost cell carcinoma (OGCC), and the special case of metastasizing ameloblastoma.
  • Odontogenic sarcomas consist of ameloblastic fibrosarcoma and ameloblastic fibrodentinosarcoma and fibroodontosarcoma.
  • Whereas metastasizing ameloblastoma can be diagnosed only after having metastasized, all other malignant odontogenic tumors present with atypia, increased cellularity and mitoses, and invasion.
  • [MeSH-minor] Ameloblastoma / classification. Ameloblastoma / pathology. Carcinoma / classification. Carcinoma / pathology. Carcinosarcoma / classification. Carcinosarcoma / pathology. Diagnosis, Differential. Humans. Jaw / pathology. Neoplasm Invasiveness. Sarcoma / classification. Sarcoma / pathology

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  • (PMID = 18392827.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
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35. Taghavi N, Mehrdad L, Rajabi M, Akbarzadeh A: A 10-year retrospective study on malignant jaw tumors in Iran. J Craniofac Surg; 2010 Nov;21(6):1816-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A 10-year retrospective study on malignant jaw tumors in Iran.
  • OBJECTIVE: The aim of this study was to review cases of malignant tumors of jaw bones diagnosed in 2 pathology centers in Tehran, Iran, during a 10-year period.
  • MATERIALS AND METHODS: Patients' records were seen at 2 teaching pathology centers of Shahid Beheshti University between March 1999 and March 2009 with histologic diagnosis of any type of malignant jaw tumors.
  • Among these, 720 cases were tumoral and 67 cases were malignant jaw tumors.
  • Osteosarcoma (41.79%) was the most common tumor in this review, which was followed by mucoepidermoid carcinoma and ameloblastic carcinoma, respectively.
  • CONCLUSIONS: There are limited studies on malignant jaw tumors in literature, but comparing our result with the available data, there were differences regarding frequency and age distribution.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Biopsy. Carcinoma, Mucoepidermoid / epidemiology. Child. Female. Humans. Iran / epidemiology. Lymphoma / epidemiology. Male. Mandibular Neoplasms / epidemiology. Maxillary Neoplasms / epidemiology. Middle Aged. Odontogenic Tumors / epidemiology. Osteosarcoma / epidemiology. Plasmacytoma / epidemiology. Retrospective Studies. Sex Factors. Young Adult

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  • (PMID = 21119429.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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36. Miyake T, Tanaka Y, Kato K, Tanaka M, Sato Y, Ijiri R, Inayama Y, Ito Y, Aoki S, Kawabe R, Tohnai I: Gene mutation analysis and immunohistochemical study of beta-catenin in odontogenic tumors. Pathol Int; 2006 Dec;56(12):732-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Six ameloblastomas (five follicular ameloblastomas and one plexiform ameloblastoma) and three malignant odontogenic tumors (one metastasizing ameloblastoma, one ameloblastic carcinoma, and one primary intraosseous odontogenic carcinoma) were investigated for CTNNB1 expression and CTNNB1 mutation.
  • Immunohistochemically, all follicular ameloblastomas and one primary intraosseous odontogenic carcinoma exhibited focal and moderate nuclear/cytoplasmic expression of CTNNB1, whereas the plexiform ameloblastoma and the remaining two malignant odontogenic tumors had entirely membranous expression.
  • The other five follicular ameloblastomas, the plexiform ameloblastoma, and the three malignant odontogenic tumors did not show mutation in exon 3 of CTNNB1.
  • These findings further confirmed that CTNNB1 mutation is not frequent in ameloblastoma and malignant odontogenic tumors, although the abnormality of Wnt signaling may be associated with some of these tumors.

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  • (PMID = 17096730.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / beta Catenin
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37. Buchner A, Merrell PW, Carpenter WM: Relative frequency of peripheral odontogenic tumors: a study of 45 new cases and comparison with studies from the literature. J Oral Pathol Med; 2006 Aug;35(7):385-91

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  • Peripheral calcifying epithelial odontogenic tumor, peripheral ameloblastic fibroma, and peripheral ameloblastic carcinoma were also identified--each comprised 2.2% (one case each).

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  • (PMID = 16827840.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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38. Kruse AL, Zwahlen RA, Grätz KW: New classification of maxillary ameloblastic carcinoma based on an evidence-based literature review over the last 60 years. Head Neck Oncol; 2009;1:31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] New classification of maxillary ameloblastic carcinoma based on an evidence-based literature review over the last 60 years.
  • BACKGROUND: The ameloblastic carcinoma is a rare malignant odontogenic tumor which rather occurs in the mandible than in the maxilla.
  • Current classifications do not consider benign histopathological features at the primary and malignant features at the metastatic tumour site.
  • METHODS: An evidence-based literature review over the last 60 years regarding ameloblastic carcinoma of the maxilla was conducted.
  • In 54% the primary diagnosis was ameloblastic carcinoma, 34.6% revealed pulmonary metastases, however, only in one patient cervical lymph node metastasis could be found.
  • Whereas two cases did not reveal malignant histopathology at the primary, they revealed malignant features at their metastatic sites.
  • CONCLUSION: It is of utmost importance to be aware of that ameloblastomas may be capable to degenerate into a "malignant" disease with recurrence and metastasis.

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  • (PMID = 19674470.001).
  • [ISSN] 1758-3284
  • [Journal-full-title] Head & neck oncology
  • [ISO-abbreviation] Head Neck Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2733136
  • [General-notes] NLM/ Original DateCompleted: 20100629
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39. Khalbuss WE, Loya A, Bazooband A: Fine-needle aspiration cytology of pulmonary ameloblastic carcinoma of mandibular origin. Diagn Cytopathol; 2006 Mar;34(3):208-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration cytology of pulmonary ameloblastic carcinoma of mandibular origin.

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  • (PMID = 16470855.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calbindin 2; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Calcium Binding Protein G
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40. Vered M, Shohat I, Buchner A, Dayan D: Myofibroblasts in stroma of odontogenic cysts and tumors can contribute to variations in the biological behavior of lesions. Oral Oncol; 2005 Nov;41(10):1028-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The study included cases of dentigerous cyst (DC, n = 7), odontogenic keratocyst-parakeratinized type (OKC-P, n = 8), orthokeratinized type (OKC-O, n = 9), ameloblastic fibroma/fibro-odontoma (AMF/O, n = 11), unicystic ameloblastoma (UAM, n = 6), and solid ameloblastoma (SAM, n = 7).
  • Cases of oral squamous cell carcinoma (SCC, n = 5) served as control.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Fibroblasts / ultrastructure. Maxillary Diseases / pathology. Odontogenic Cysts / pathology. Odontogenic Tumors / pathology. Odontoma / pathology

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  • (PMID = 16139563.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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41. Holsinger FC, Hafemeister AC, Hicks MJ, Sulek M, Huh WW, Friedman EM: Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: a 45-year multi-institutional review. Ear Nose Throat J; 2010 Nov;89(11):534-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lesions included adnexal neoplasm, ameloblastic fibro-odontoma, basal cell carcinoma, benign fibrous histiocytoma, blue nevus, chondrosarcoma, compound nevus, epithelioma adenoides cysticum, esthesioneuroblastoma, Ewing sarcoma, fibrosarcoma, giant cell granuloma, granulocytic sarcoma, hemangioma, hemangiopericytoma, Langerhans cell histiocytosis, lymphangioma, lymphoma, melanoma, neuroblastoma, neurofibroma, ossifying osteofibroma, osteochondroma, osteosarcoma, port wine stain, rhabdomyosarcoma, Spitz nevus, and xanthogranuloma.

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  • (PMID = 21086277.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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