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Items 1 to 31 of about 31
1. Pérez-Campagne E, Guex-Crosier Y, Schalenbourg A, Uffer S, Zografos L: [Giant nodular posterior scleritis compatible with ocular sarcoidosis simulating choroidal melanoma]. Arch Soc Esp Oftalmol; 2007 Sep;82(9):563-6
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  • [Title] [Giant nodular posterior scleritis compatible with ocular sarcoidosis simulating choroidal melanoma].
  • [Transliterated title] Escleritis nodular posterior gigante compatible con sarcoidosis ocular simulando un melanoma de la coroides.
  • CASE REPORT: A 30-year-old man was referred to our ocular oncology service with a diagnosis of amelanotic choroidal melanoma of the left eye.
  • DISCUSSION: The diagnosis of giant nodular posterior scleritis, as suggested by ultrasonography, was confirmed by biopsy.
  • Sarcoidosis continues to be a challenge in diagnosis.
  • It is important to distinguish nodular posterior scleritis from choroidal melanoma.
  • [MeSH-major] Choroid Neoplasms / diagnosis. Melanoma / diagnosis. Sarcoidosis / diagnosis. Scleritis / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Eye Diseases / complications. Eye Diseases / diagnosis. Humans. Male


2. Gensburger M, Kodjikian L, Devouassoux-Shisheboran M, Grange JD: [Thirty-five years of follow-up before enucleation for malignant choroidal melanoma. A case report]. J Fr Ophtalmol; 2006 Mar;29(3):307-11
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  • [Title] [Thirty-five years of follow-up before enucleation for malignant choroidal melanoma. A case report].
  • We report the case of a patient with a unilateral chorioretinal lesion that evolved over 35 years before enucleation provided the diagnosis of amelanotic choroidal melanoma.
  • [MeSH-major] Choroid Neoplasms / surgery. Eye Enucleation. Melanoma / surgery

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  • (PMID = 16557176.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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3. Lee SH, Hong JS, Choi JH, Chung WS: Choroidal schwannoma. Acta Ophthalmol Scand; 2005 Dec;83(6):754-6
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  • CONCLUSIONS: We enucleated the eyeball with a clinical diagnosis of choroidal amelanotic melanoma, but the tumor was finally diagnosed as schwannoma.
  • [MeSH-minor] Aged. Diagnosis, Differential. Eye Enucleation. Female. Humans. Magnetic Resonance Imaging. Visual Acuity

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  • (PMID = 16396657.001).
  • [ISSN] 1395-3907
  • [Journal-full-title] Acta ophthalmologica Scandinavica
  • [ISO-abbreviation] Acta Ophthalmol Scand
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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4. Stringa O, Valdez R, Beguerie JR, Abbruzzese M, Lioni M, Nadales A, Iudica F, Venditti J, San Roman A: Primary amelanotic melanoma of the esophagus. Int J Dermatol; 2006 Oct;45(10):1207-10
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  • [Title] Primary amelanotic melanoma of the esophagus.
  • Primary melanoma of the esophagus (PME) is an uncommon malignancy with less than 250 cases reported in the literature.
  • Amelanotic PME is exceedingly rare and accounts for 10-25% of melanomas of the esophagus.
  • No skin or eye melanoma lesions were found.
  • A diagnosis of primary amelanotic melanoma of the esophagus was made.
  • Fourteen months after diagnosis the patient developed disseminated PME.
  • [MeSH-major] Esophageal Neoplasms / pathology. Melanoma, Amelanotic / pathology

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  • (PMID = 17040443.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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5. Harasymowycz P, Boucher MC, Corriveau C, Gauthier D, Allaire G: Choroidal amelanotic melanoma in a patient with oculocutaneous albinism. Can J Ophthalmol; 2005 Dec;40(6):754-8
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  • [Title] Choroidal amelanotic melanoma in a patient with oculocutaneous albinism.
  • CASE REPORT: We describe the clinical presentation of a choroidal amelanotic melanoma in a 46-year-old woman with oculocutaneous albinism.
  • Microscopic findings and histopathological features, demonstrating a spindle B-cell melanoma of the choroid, are also reviewed.
  • COMMENTS: Magnetic resonance imaging may be helpful in diagnosing amelanotic melanoma in patients with oculocutaneous albinism.

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  • (PMID = 16391642.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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6. Duong HV, McLean IW, Beahm DE: Bilateral diffuse melanocytic proliferation associated with ovarian carcinoma and metastatic malignant amelanotic melanoma. Am J Ophthalmol; 2006 Oct;142(4):693-5
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  • [Title] Bilateral diffuse melanocytic proliferation associated with ovarian carcinoma and metastatic malignant amelanotic melanoma.
  • PURPOSE: To report a case of metastatic malignant amelanotic melanoma to the skin from a patient diagnosed with bilateral diffuse uveal melanocytic proliferation (BDUMP).
  • METHODS: We studied the case of a 66-year-old Caucasian woman with gradual onset of blurred vision in her right eye followed by her left eye.
  • RESULTS: The hematoxylin and eosin, S-100, and HMB-45 stains were consistent with metastatic malignant amelanotic melanoma to the skin.
  • [MeSH-major] Melanocytes / pathology. Melanoma, Amelanotic / secondary. Ovarian Neoplasms / pathology. Paraneoplastic Syndromes / pathology. Skin Neoplasms / secondary. Uveal Diseases / diagnosis
  • [MeSH-minor] Aged. Antigens, Neoplasm / analysis. Cell Proliferation. Eye Enucleation. Female. Humans. Immunohistochemistry. Melanoma-Specific Antigens. Neoplasm Proteins / analysis. Retrospective Studies. S100 Proteins / analysis

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  • (PMID = 17011873.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
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7. Tolleson WH, Doss JC, Latendresse J, Warbritton AR, Melchior WB Jr, Chin L, Dubielzig RR, Albert DM: Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice. Arch Ophthalmol; 2005 Aug;123(8):1088-94
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  • [Title] Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice.
  • OBJECTIVE: To characterize a murine model of spontaneous amelanotic melanoma arising in the uvea of transgenic mice bearing a targeted deletion of the Ink4a/Arf tumor suppressor locus (exons 2 and 3) and expressing human H-ras controlled by the human tyrosinase promoter.
  • RESULTS: Uveal melanomas were locally invasive but confined to the eye, with no evidence of metastasis.
  • CONCLUSION: Spontaneous uveal malignant melanomas occurring in male Tyr-RAS+ Ink4a/Arf-/- transgenic mice arise within the choroid or ciliary body and share histopathological features characteristic of human uveal melanoma.
  • CLINICAL RELEVANCE: Uveal melanoma research has benefited from xenograft models, but engineered mouse models of spontaneous uveal amelanotic melanoma will undoubtedly further our understanding of the genetic underpinning for this disease.
  • [MeSH-major] Cyclin-Dependent Kinase Inhibitor p16 / genetics. Gene Deletion. Genes, ras / genetics. Melanoma, Amelanotic / pathology. Monophenol Monooxygenase / genetics. Tumor Suppressor Protein p14ARF / genetics. Uveal Neoplasms / pathology

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  • (PMID = 16087843.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY 01917; United States / NCI NIH HHS / CA / R01 CA 93947
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cdkn2a protein, mouse; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Tumor Suppressor Protein p14ARF; EC 1.14.18.1 / Monophenol Monooxygenase
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8. Schefler AC, Mutapcic L, Murray TG, Dubovy SR: Optic nerve invasion from an amelanotic peripapillary choroidal melanoma. Retin Cases Brief Rep; 2009;3(4):329-32

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  • [Title] Optic nerve invasion from an amelanotic peripapillary choroidal melanoma.
  • PURPOSE: To report an unusual case of an amelanotic optic nerve head melanoma.
  • PATIENTS/METHODS/RESULTS: This is a retrospective case report of an 81-year-old woman with a slowly enlarging amelanotic optic nerve head lesion.
  • Histopathologic evaluation of the lesion after enucleation revealed a peripapillary choroidal melanoma.
  • The lesion was highly atypical in that the patient's visual acuity was excellent despite the lesion's growth and the intraocular pressure did not differ from the fellow eye.
  • CONCLUSION: Optic nerve invasion by choroidal melanoma is a rare event, which is typically associated with poor visual acuity, elevated intraocular pressure, and large necrotic lesions; however, invasive melanoma with optic nerve invasion may occur in the absence of these classic findings.

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  • (PMID = 25389839.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Soucek P, Cihelkova I: Photodynamic therapy with verteporfin in subfoveal amelanotic choroidal melanoma (A controlled case). Neuro Endocrinol Lett; 2006 Feb-Apr;27(1-2):145-8
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  • [Title] Photodynamic therapy with verteporfin in subfoveal amelanotic choroidal melanoma (A controlled case).
  • A 57-year old man with 2.7 mm thick subfoveal amelanotic choroidal melanoma of the right eye was indicated for photodynamic therapy with verteporfin.
  • [MeSH-major] Eye Neoplasms / therapy. Melanoma, Amelanotic / therapy. Photochemotherapy. Photosensitizing Agents / therapeutic use. Porphyrins / therapeutic use
  • [MeSH-minor] Eye / ultrasonography. Humans. Male. Middle Aged

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  • (PMID = 16648785.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Porphyrins; 129497-78-5 / verteporfin
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10. Kurotaki T, Tomonari Y, Kanno T, Wako Y, Tsuchitani M: Malignant amelanotic melanoma behind the left eye in a female Crj:CD(SD)IGS rat: a case report. Vet Pathol; 2008 Sep;45(5):681-4
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  • [Title] Malignant amelanotic melanoma behind the left eye in a female Crj:CD(SD)IGS rat: a case report.
  • A tumor behind the left eye in a female Crj:CD(SD)IGS rat was investigated histopathologically, immunohistopathologically, and electron microscopically.
  • It consisted of various tumor cells; namely, spindle-shaped, epithelioid, anaplastic melanoma cells, and had prominent eosinophilic cytoplasm and nuclei with a greater variation in size.
  • This is the first report describing an amelanotic melanoma in the head of an albino rat.
  • [MeSH-major] Bone Neoplasms / veterinary. Eye Neoplasms / veterinary. Melanoma, Amelanotic / veterinary. Rodent Diseases / pathology

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  • (PMID = 18725473.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Becerra EM, Saornil MA, Blanco G, Méndez MC, Muiños Y, Esteban MR: Cavitary choroidal melanoma. Can J Ophthalmol; 2005 Oct;40(5):619-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavitary choroidal melanoma.
  • CASE REPORT: We report an unusual case of cavitary choroidal melanoma.
  • The results of ultrasonography, magnetic resonance imaging, computed tomography, and immunohistochemical studies are presented for a 38-year-old woman who developed an amelanotic tumor in the posterior choroid.
  • Enucleation was performed and histopathologic examination showed a choroidal melanoma of spindle cell type, with intratumoral cavitations lined by flattened tumor cells.
  • Uveal melanoma should be included in the differential diagnosis of choroidal cavitary lesions.
  • As far as we know, this is the second documented clinicopathologic correlation of a cavitary choroidal melanoma.

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  • (PMID = 16391628.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / Vimentin
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12. Mahajan A, Shields CL, Eagle RC Jr, Mashayekhi A, Freire JE, Shields JA: Conjunctival melanoma 3 years after radiation and chemotherapy for retinoblastoma. J Pediatr Ophthalmol Strabismus; 2007 Sep-Oct;44(5):300-2
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  • [Title] Conjunctival melanoma 3 years after radiation and chemotherapy for retinoblastoma.
  • An 8-month-old infant with advanced bilateral retinoblastoma was managed with enucleation of the right eye and chemotherapy and radiotherapy of the left eye.
  • Excisional biopsy revealed an amelanotic melanoma of the conjunctiva with superficial orbital invasion.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Melanoma, Amelanotic / pathology. Neoplasms, Second Primary / pathology. Retinal Neoplasms / therapy. Retinoblastoma / therapy
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carboplatin / administration & dosage. Combined Modality Therapy. Etoposide / administration & dosage. Eye Enucleation. Humans. Infant. Male. Radiotherapy, High-Energy. Vincristine / administration & dosage

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  • (PMID = 17913173.001).
  • [ISSN] 0191-3913
  • [Journal-full-title] Journal of pediatric ophthalmology and strabismus
  • [ISO-abbreviation] J Pediatr Ophthalmol Strabismus
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; BG3F62OND5 / Carboplatin
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13. Bongiorno MR, Lodato G, Affronti A, Aragona F, Aricò M: Amelanotic conjunctival melanoma. Cutis; 2006 Jun;77(6):377-81

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  • [Title] Amelanotic conjunctival melanoma.
  • Conjunctival melanoma is a rare condition of the eye pigment predominantly affecting white adults.
  • We describe a 32-year-old white man with an amelanotic malignant melanoma of the conjunctiva that is not associated with primary acquired melanosis (PAM) or melanocytic nevus.
  • The patient presented with a 2-year history of nonpigmented vascularized nodules of the right eye.
  • HMB45 protein was highly positive in the melanoma cells.
  • The de novo amelanotic malignant melanoma of the conjunctiva we describe is an extremely uncommon tumor mainly affecting white adults.
  • [MeSH-major] Conjunctiva / pathology. Conjunctival Neoplasms / pathology. Melanoma, Amelanotic / pathology

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  • (PMID = 16838771.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Lin JY, Liu D, Li EJ: [Clinical and pathological features of 26 cases of conjunctival melanoma]. Zhonghua Yan Ke Za Zhi; 2010 Apr;46(4):308-11
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  • [Title] [Clinical and pathological features of 26 cases of conjunctival melanoma].
  • OBJECTIVE: To improve the knowledge of clinical and pathological features of conjunctival melanoma, in order to have an early diagnosis and treatment.
  • The clinical and pathological features of 26 cases of conjunctival melanoma were analyzed.
  • These cases were treated from May in 1985 to June in 2007 in Tianjin Eye Hospital.
  • Twenty two cases were epitheloid-cell-type melanoma, 4 cases were mixed-cell-type melanoma.
  • There were 3 amelanotic melanomas, the tumor cells were positively stained with S-100 and HMB-45.
  • CONCLUSIONS: Conjunctival melanoma mainly arises from malignant transformation of PAM or conjunctival nevi and consists of epitheloid melanotic tumor cells.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Melanoma / pathology

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  • (PMID = 20654056.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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15. Russo A, Coupland SE, O'Keefe M, Damato BE: Choroidal melanoma in a 7-year-old child treated by trans-scleral local resection. Graefes Arch Clin Exp Ophthalmol; 2010 May;248(5):747-9
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  • [Title] Choroidal melanoma in a 7-year-old child treated by trans-scleral local resection.
  • PURPOSE: To report a choroidal melanoma in a 7-year-old child treated by trans-scleral local resection and adjuvant brachytherapy with a family history of neurofibromatosis type I (NF1) and cutaneous melanoma.
  • PATIENT AND METHODS: A 7-year-old child was referred for treatment of a choroidal tumor in her left eye with a differential diagnosis of melanoma, neurilemmoma, leiomyoma, and neurofibroma.
  • RESULTS: Histopathology and immunohistochemistry of the specimen diagnosed an amelanotic melanoma of spindle cell type, with a moderately high number of mitoses (7/40 HPF).
  • Although the follow-up is short, our patient retained the eye with good vision and our cytogenetic studies allowed us to reassure the mother.
  • [MeSH-major] Choroid Neoplasms / surgery. Melanoma / surgery. Ophthalmologic Surgical Procedures

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  • (PMID = 20143236.001).
  • [ISSN] 1435-702X
  • [Journal-full-title] Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
  • [ISO-abbreviation] Graefes Arch. Clin. Exp. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ruthenium Radioisotopes
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16. Yarovoy AA, Magaramov DA, Bulgakova ES: Which choroidal melanoma should be treated with primary transpupillary thermotherapy? Our experience from 78 patients. Eur J Ophthalmol; 2010 Jan-Feb;20(1):186-93
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  • [Title] Which choroidal melanoma should be treated with primary transpupillary thermotherapy? Our experience from 78 patients.
  • Logistic regression showed the main predictive factors for TTT failure to be tumor height (OR=6.85; 95% CI=1.2-38.1; p=0.02), basal diameter (OR=22.85; 95% CI=3.6-144.7; p=0.0003), amelanotic pigmentation (for primary failure, OR=9.18; 95% CI=1.7-49.2; p=0.008), high maximum systolic velocity (for primary failure, OR=13.6; 95% CI=2.3-81.7; p=0.003), subretinal fluid (OR=11.04; 95% CI=1.2-100.4; p=0.03), and incomplete regression (OR=30.62; 95% CI=6.0-156.4; p=0.00001).
  • [MeSH-major] Choroid Neoplasms / therapy. Hyperthermia, Induced. Melanoma / therapy. Neoplasm Recurrence, Local / therapy
  • [MeSH-minor] Adult. Aged. Brachytherapy. Eye Enucleation. Female. Follow-Up Studies. Humans. Male. Middle Aged. Patient Selection. Prospective Studies. Pupil. Treatment Outcome. Visual Acuity / physiology

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  • (PMID = 19882517.001).
  • [ISSN] 1120-6721
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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17. LeRoy BE, Knight MC, Eggleston R, Torres-Velez F, Harmon BG: Tail-base mass from a "horse of a different color". Vet Clin Pathol; 2005;34(1):69-71
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  • Additional masses were found around the eye and shoulder.
  • The cytologic and histopathologic diagnoses were amelanotic melanoma.
  • In this report, we describe the cytopathologic features of an aggressive amelanotic melanoma in a non-grey horse and emphasize the unique correlation between cytologic and histologic findings.

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  • (PMID = 15732023.001).
  • [ISSN] 0275-6382
  • [Journal-full-title] Veterinary clinical pathology
  • [ISO-abbreviation] Vet Clin Pathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Zalaudek I, Kreusch J, Giacomel J, Ferrara G, Catricalà C, Argenziano G: How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part II. Nonmelanocytic skin tumors. J Am Acad Dermatol; 2010 Sep;63(3):377-86; quiz 387-8
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  • In contrast to the rarity of amelanotic melanoma, nonmelanoma skin cancer commonly lacks pigmentation.
  • Dermoscopy improves the clinical diagnosis of nonpigmented skin tumors by allowing the visualization of specific vascular structures that are usually not visible to the naked eye.
  • Dermoscopic vascular patterns of several nonmelanocytic nonpigmented skin tumors, such as sebaceous hyperplasia, seborrheic keratosis, clear cell acanthoma, Bowen disease, or nodular cystic basal cell carcinoma are highly specific, allowing a ready diagnosis in most cases.
  • [MeSH-major] Dermoscopy / methods. Skin / blood supply. Skin Neoplasms / blood supply. Skin Neoplasms / diagnosis
  • [MeSH-minor] Blood Vessels / pathology. Bowen's Disease / blood supply. Bowen's Disease / diagnosis. Bowen's Disease / pathology. Carcinoma, Basal Cell / blood supply. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / pathology. Carcinoma, Squamous Cell / blood supply. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Education, Medical, Continuing. Female. Humans. Keratosis, Seborrheic / diagnosis. Keratosis, Seborrheic / pathology. Male. Melanoma, Amelanotic / blood supply. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / pathology

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  • [Copyright] Copyright 2010 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20708470.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 43
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19. Natesh S, Chin KJ, Finger PT: Choroidal metastases fundus autofluorescence imaging: correlation to clinical, OCT, and fluorescein angiographic findings. Ophthalmic Surg Lasers Imaging; 2010 Jul-Aug;41(4):406-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: All tumors were amelanotic, although 8 exhibited surface pigmentation.
  • [MeSH-major] Choroid Neoplasms / diagnosis. Choroid Neoplasms / secondary. Fluorescein Angiography. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / secondary. Tomography, Optical Coherence

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  • (PMID = 20438045.001).
  • [ISSN] 1938-2375
  • [Journal-full-title] Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
  • [ISO-abbreviation] Ophthalmic Surg Lasers Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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20. Rumelt S, Pe'er J, Rubin PA: The clinicopathological spectrum of benign peripunctal tumours. Graefes Arch Clin Exp Ophthalmol; 2005 Feb;243(2):113-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eleven out of 175 (6.3%) peripunctal disorders and out of approximately 4,000 (0.27%) surgical oculoplastics patients were seen at Massachusetts Eye & Ear Infirmary, Boston.
  • [MeSH-minor] Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / surgery. Adult. Aged. Diagnosis, Differential. Epidermal Cyst / pathology. Epidermal Cyst / surgery. Female. Granuloma, Pyogenic / pathology. Granuloma, Pyogenic / surgery. Humans. Male. Melanoma, Amelanotic / pathology. Melanoma, Amelanotic / surgery. Middle Aged. Nevus, Pigmented / pathology. Nevus, Pigmented / surgery. Papilloma / pathology. Papilloma / surgery. Retrospective Studies

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  • (PMID = 15558295.001).
  • [ISSN] 0721-832X
  • [Journal-full-title] Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
  • [ISO-abbreviation] Graefes Arch. Clin. Exp. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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21. Bakri SJ, Singh AD, Lowder CY, Chalita MR, Li Y, Izatt JA, Rollins AM, Huang D: Imaging of iris lesions with high-speed optical coherence tomography. Ophthalmic Surg Lasers Imaging; 2007 Jan-Feb;38(1):27-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS AND METHODS: High-speed (2,000-4,000 axial-scan/sec and 4-16 frames/sec) 1.3-micron wavelength anterior segment OCT prototypes were used to image 6 eyes of 6 patients with a variety of iris lesions, including focal iris nevus, diffuse iris nevus, amelanotic iris nevus, iris melanocytosis, and iris melanoma.
  • [MeSH-major] Iris / pathology. Iris Neoplasms / diagnosis. Melanoma / diagnosis. Nevus / diagnosis. Tomography, Optical Coherence / methods
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Microscopy, Acoustic. Middle Aged

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  • (PMID = 17278533.001).
  • [ISSN] 1542-8877
  • [Journal-full-title] Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
  • [ISO-abbreviation] Ophthalmic Surg Lasers Imaging
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / R24 EY13015
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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22. Zalaudek I, Kreusch J, Giacomel J, Ferrara G, Catricalà C, Argenziano G: How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part I. Melanocytic skin tumors. J Am Acad Dermatol; 2010 Sep;63(3):361-74; quiz 375-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Dermoscopy is a noninvasive tool that can be helpful in the diagnosis of nonpigmented skin tumors.
  • This is because dermoscopy permits the visualization of key vascular structures that are usually not visible to the naked eye.
  • Aside from vascular morphology, the architectural arrangement of vessels within the tumor and the presence of additional dermoscopic clues are equally important for the diagnosis.
  • [MeSH-major] Blood Vessels / pathology. Dermoscopy / methods. Melanocytes / pathology. Skin Neoplasms / blood supply. Skin Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Education, Medical, Continuing. Female. Humans. Male. Melanoma / blood supply. Melanoma / diagnosis. Melanoma / pathology. Melanoma, Amelanotic / blood supply. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / pathology. Regional Blood Flow. Skin / blood supply

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  • [Copyright] Copyright 2010 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20708469.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 47
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23. Jain V, Dabir S, Shome D, Dadu T, Natarajan S: Aspergillus iris granuloma: a case report with review of literature. Surv Ophthalmol; 2009 Mar-Apr;54(2):286-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report the case of a 25-year-old male patient who presented with complaints of redness, photophobia, and decreased vision in the right eye of a week's duration.
  • Differential diagnoses of a fungal granuloma, a medulloepithelioma, and an amelanotic melanoma were considered.
  • Definitive differentiation of this rare entity from a foreign body, amelanotic melanoma, and other inflammatory conditions such as sarcoidosis and tuberculosis, may be possible only on microbiological and histo-pathological evaluation.
  • [MeSH-major] Aspergillosis / microbiology. Aspergillus fumigatus / isolation & purification. Eye Infections, Fungal / microbiology. Granuloma, Giant Cell / microbiology. Iris Diseases / microbiology

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  • (PMID = 19298905.001).
  • [ISSN] 0039-6257
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antifungal Agents; 0 / Aza Compounds; 0 / DNA, Fungal; 0 / Fluoroquinolones; 0 / Quinolines; 7C0697DR9I / Atropine; 8O0C852CPO / Natamycin; U188XYD42P / moxifloxacin
  • [Number-of-references] 18
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24. Elizalde J, Ubia S, Barraquer RI: Adenoma of the nonpigmented ciliary epithelium. Eur J Ophthalmol; 2006 Jul-Aug;16(4):630-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenoma of the non pigmented ciliary epithelium may mimic an amelanotic melanoma.
  • Partial lamellar sclerouvectomy is an effective method to manage this condition and to confirm the diagnosis.
  • [MeSH-major] Adenoma / pathology. Ciliary Body / pathology. Pigment Epithelium of Eye / pathology. Uveal Neoplasms / pathology

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  • (PMID = 16952109.001).
  • [ISSN] 1120-6721
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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25. Riveros LG, Simpson ER, DeAngelis DD, Howarth D, McGowan H, Kassel E: Primary intraosseous hemangioma of the orbit: an unusual presentation of an uncommon tumor. Can J Ophthalmol; 2006 Oct;41(5):630-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CASE REPORT: An asymptomatic patient was referred for assessment of an intraocular amelanotic mass in her left eye.
  • This abnormality was defined with ultrasound biomicroscopy and standard ultrasound, but because the appearance was not typical of a melanoma or other choroidal infiltrate, magnetic resonance images and computed tomograms of the orbits were obtained, identifying an extraocular mass arising from the zygomatic rim.
  • COMMENTS: The diagnosis of intraosseous hemangioma, because of its low incidence and unusual manner of presentation, can be challenging.
  • Computed tomography and biopsy are helpful in making a definitive diagnosis.

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  • (PMID = 17016539.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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26. Perez B, Shields CL, Shields JA: Large turbid retinal pigment epithelial detachment camouflaging an underlying choroidal nevus. Retin Cases Brief Rep; 2009;3(2):147-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: A 51-year-old woman was referred with an asymptomatic yellow subretinal mass in the left eye presumed to represent a choroidal metastasis or melanoma.
  • Ophthalmoscopy of the left eye revealed a well defined, abruptly elevated, dome-shaped amelanotic lesion temporal to the macular area measuring 4 mm in basal dimension and 2.2 mm in thickness.

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  • (PMID = 25391059.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Ni-Komatsu L, Orlow SJ: Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: effects of altering intracellular pH and pink-eyed dilution gene expression. Exp Eye Res; 2006 Mar;82(3):519-28
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Remarkably, this heterologous expression system recapitulates the defective processing and mistrafficking of tyrosinase observed in OCA2 albino melanocytes and certain amelanotic melanoma cells.
  • [MeSH-major] Albinism, Oculocutaneous / enzymology. Epithelial Cells / enzymology. Membrane Transport Proteins / genetics. Monophenol Monooxygenase / genetics. Pigment Epithelium of Eye / enzymology

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  • (PMID = 16199032.001).
  • [ISSN] 0014-4835
  • [Journal-full-title] Experimental eye research
  • [ISO-abbreviation] Exp. Eye Res.
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / AR41880; United States / NEI NIH HHS / EY / EY10223
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Melanins; 0 / Membrane Transport Proteins; 0 / OCA2 protein, human; 42HK56048U / Tyrosine; EC 1.14.18.1 / Monophenol Monooxygenase
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28. Levecq L, De Potter P, Godfraind C, Guagnini AP, Kozyreff A: Choroidal metastasis from carcinoma of the bladder. Retin Cases Brief Rep; 2007;1(4):251-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A 58-year-old man with a history of urothelial bladder carcinoma developed progressive decreased visual acuity in the right eye.
  • Fundus examination showed an amelanotic choroidal tumor simulating a choroidal melanoma.
  • Results of ancillary diagnostic tests, needle aspiration biopsy, and systemic workup failed to confirm the diagnosis of choroidal metastasis.
  • The patient was treated with enucleation the affected right eye.
  • RESULTS: Histopathologic analysis of the enucleated eye disclosed a choroidal metastatic carcinoma with urothelial features similar to those of the bladder carcinoma excised previously.

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  • (PMID = 25390994.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Chen CL, Tai MC, Chen JT, Chen CH, Jin JS, Lu DW: A rare case of conjunctival myxoma and a review of the literature. Ophthalmologica; 2008;222(2):136-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: To report on an 11-year-old boy with a painless slow-growing temporal bulbar conjunctival mass of his left eye.
  • RESULTS: An 11-year-old boy presented with a painless slow-growing mass in the temporal bulbar conjunctiva of his left eye, which had been noted for 1 year.
  • After ophthalmic and systemic evaluations, the clinical differential diagnosis at the time included amelanotic naevus, amelanotic melanoma, myxoma, fibrous histiocytoma, reactive lymphoid hyperplasia and lipoma.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Conjunctival Neoplasms / surgery. Myxoma / diagnosis. Myxoma / surgery
  • [MeSH-minor] Child. Diagnosis, Differential. Humans. Male. Rare Diseases / diagnosis

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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18303236.001).
  • [ISSN] 1423-0267
  • [Journal-full-title] Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
  • [ISO-abbreviation] Ophthalmologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 26
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30. Shrestha A, Adhikari RC, Saiju R: Retinoblastoma in a 37 years old man in Nepal: a case report. Kathmandu Univ Med J (KUMJ); 2010 Apr-Jun;8(30):247-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Initially provisional diagnosis of amelanotic melanoma was made.
  • A diagnosis of poorly differentiated Retinoblastoma was made with TNM (AJCC) stage as T1NXMX.
  • Although retinoblastoma is rare in adult, we suggest keeping retinoblastoma in differential diagnosis of intraocular mass until proven histopathology report is available.
  • [MeSH-major] Retinal Neoplasms / diagnosis. Retinoblastoma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Eye Enucleation. Humans. Male. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 21209546.001).
  • [ISSN] 1812-2078
  • [Journal-full-title] Kathmandu University medical journal (KUMJ)
  • [ISO-abbreviation] Kathmandu Univ Med J (KUMJ)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
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31. Lai WW, Zhou YS, Lam DS, Freeman WR, Chow DR, Murray TG: Diagnostic and therapeutic challenges. Retina; 2006 Jan;26(1):96-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Choroid Neoplasms / diagnosis. Choroiditis / diagnosis. Lymphoproliferative Disorders / diagnosis. Melanoma, Amelanotic / diagnosis. Retinal Neoplasms / diagnosis. Retinitis / diagnosis
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Fluorescein Angiography. Humans. Male. Middle Aged

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  • (PMID = 16395146.001).
  • [ISSN] 0275-004X
  • [Journal-full-title] Retina (Philadelphia, Pa.)
  • [ISO-abbreviation] Retina (Philadelphia, Pa.)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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