[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 175
1. Castillo O, Frisancho O, Palomino A: [Cecal amelanotic melanoma]. Rev Gastroenterol Peru; 2010 Oct-Dec;30(4):368-71
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cecal amelanotic melanoma].
  • [Transliterated title] Melanoma amelanótico en ciego.
  • Subsequently, we confirmed the presence of red blood in stools, like enterorrhagia and underwent a colonoscopy, in which two elevated lesions were found in the cecum: a pedunculated (with active bleeding, oozing) and other sessile; both were removed. the pathology showed that corresponded to amelanotic melanoma in cecal region.
  • Physical examination revealed no malignant skin lesions.
  • We report this case, because gastrointestinal bleeding is an unusual clinical presentation of malignant melanoma.
  • [MeSH-major] Cecal Neoplasms / pathology. Melanoma / pathology

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21263766.001).
  • [ISSN] 1022-5129
  • [Journal-full-title] Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
  • [ISO-abbreviation] Rev Gastroenterol Peru
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Peru
  •  go-up   go-down


2. Zielińska K, Kozłowska K, Cichorek M, Wachulska M: Fas and FasL expression on cells of two transplantable melanoma lines according to their different biological properties. Folia Histochem Cytobiol; 2008;46(3):337-43
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fas and FasL expression on cells of two transplantable melanoma lines according to their different biological properties.
  • In tumours (e.g. melanoma), FasL expression possibly counteracts the Fas-positive effector T cells that infiltrate into tumours, and consequently the Fas/FasL interaction can contribute to the escape of tumour cells from the systemic immune response.
  • In this study we examined differences in Fas and FasL expression on cells from the hamster melanotic melanoma line (Ma) and a more aggressive amelanotic melanoma line (Ab).
  • We also tried to find out whether the Fas/FasL expression induces an ability to undergo spontaneous apoptosis in these two transplantable melanoma lines.
  • Isolated transplantable melanoma cells were incubated for 4 and 24 hours and after that time the expression of Fas and FasL was estimated by flow cytometry.
  • The results show that there was no Fas expression, although FasL was detected on both melanoma cell lines.
  • Therefore the data reported by other authors indicate that a lack or a low level of Fas expression and an ectopic expression of FasL on melanoma cells can be an escape mechanism of the tumour, to avoid host immune responses.
  • The content of FasL-positive melanotic melanoma cells was higher than in amelanotic melanoma cells and increased with the prolongation of the incubation time.
  • FasL expression on amelanotic melanoma cells was detected after 24 hours at a level similar to that on melanotic melanoma cells after 4 hours incubation time.
  • FasL expression on melanoma cells can induce apoptosis in cytotoxic T lymphocytes and NK cells which are responsible for tumour cells elimination.
  • The results obtained suggest that the Fas/FasL system does not play any significant role in spontaneous apoptosis of two melanoma cell lines.

  • MedlinePlus Health Information. consumer health - Melanoma.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19056538.001).
  • [ISSN] 1897-5631
  • [Journal-full-title] Folia histochemica et cytobiologica
  • [ISO-abbreviation] Folia Histochem. Cytobiol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antigens, CD95; 0 / Fas Ligand Protein
  •  go-up   go-down


3. Dubrey S, Grocott-Mason R, Mittal T, Burke M: Massive cardiac invasion by amelanotic melanoma with obstructive clinical features. Postgrad Med J; 2008 Mar;84(989):163-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Massive cardiac invasion by amelanotic melanoma with obstructive clinical features.
  • Reports of malignant melanoma involving the heart usually describe metastatic spread of pigmented (melanotic) forms of this tumour.
  • The case is unusual in relation to the extreme size of this amelanotic melanoma at presentation and the fact that it appears to be a solitary metastasis.
  • [MeSH-major] Cardiac Tamponade / etiology. Heart Neoplasms / secondary. Melanoma, Amelanotic / secondary. Skin Neoplasms

  • MedlinePlus Health Information. consumer health - Pericardial Disorders.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18372490.001).
  • [ISSN] 1469-0756
  • [Journal-full-title] Postgraduate medical journal
  • [ISO-abbreviation] Postgrad Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


Advertisement
4. Grenader T, Isacson R, Reinus C, Rosengarten O, Barenholz O, Hyman J, Gabizon A, Beller U: Primary amelanotic melanoma of the vagina. Onkologie; 2008 Sep;31(8-9):474-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic melanoma of the vagina.
  • BACKGROUND: Primary malignant melanoma of the vagina is extremely rare, accounting for 0.3-0.8% of all malignant melanomas.
  • True amelanotic vaginal melanoma showing no melanin on histological examination is exceedingly rare, accounting for only 2% of all vaginal melanomas.
  • CASE REPORT: We describe a 31-year-old female patient who presented with locally advanced amelanotic melanoma of the vagina, with no evidence of metastatic spread on the computerized tomography (CT) scan, but who was subsequently diagnosed as suffering from metastatic disease by positron emission tomography (PET)-CT performed a few weeks following posterior pelvic exenteration.
  • CONCLUSION: Specific immunohistochemical staining with melanoma markers should be performed to confirm or exclude a diagnosis of amelanotic melanoma in all patients presenting with a vaginal mass composed of undifferentiated epithelioid malignant cells.
  • Fluorodeoxyglucose (FDG)-PET-CT should be performed as part of the preoperative evaluation, to identify the presence or absence of metastatic disease in all patients with vaginal melanoma.
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / surgery. Vaginal Neoplasms / diagnosis. Vaginal Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Vaginal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18787356.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


5. Nejc D, Piekarski J, Pasz-Walczak G, Wroński K, Pluta P, Jeziorski A: The first description of sentinel node biopsy in a patient with amelanotic melanoma of the glans penis. Melanoma Res; 2005 Dec;15(6):565-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The first description of sentinel node biopsy in a patient with amelanotic melanoma of the glans penis.
  • We present the first description of sentinel node biopsy in a patient with amelanotic melanoma of the glans penis.
  • Pathologic examination of the postoperative specimen revealed the presence of a very rare malignancy--amelanotic melanoma.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Penile Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16314746.001).
  • [ISSN] 0960-8931
  • [Journal-full-title] Melanoma research
  • [ISO-abbreviation] Melanoma Res.
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


6. Pizzichetta MA, Canzonieri V, Massarut S, Baresic T, Borsatti E, Menzies SW: Pitfalls in the dermoscopic diagnosis of amelanotic melanoma. J Am Acad Dermatol; 2010 May;62(5):893-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pitfalls in the dermoscopic diagnosis of amelanotic melanoma.
  • [MeSH-major] Dermoscopy. Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] J Am Acad Dermatol. 2007 Mar;56(3):508-13 [17113189.001]
  • (PMID = 20398822.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] United States
  •  go-up   go-down


7. An J, Li B, Wu L, Lu H, Li N: Primary malignant amelanotic melanoma of the female genital tract: report of two cases and review of literature. Melanoma Res; 2009 Aug;19(4):267-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary malignant amelanotic melanoma of the female genital tract: report of two cases and review of literature.
  • Primary amelanotic melanoma of the female genital tract usually has a poor outcome as a consequence of delayed diagnosis and lack of standardized treatment.
  • We report two cases of this disease originating in the vulva and uterine cervix, respectively.
  • Compared with amelanotic melanoma of the female genital tract of the vulva, disease of the cervix is more likely to be misdiagnosed, identified at a later stage, and have a poorer outcome.
  • [MeSH-major] Melanoma, Amelanotic. Uterine Cervical Neoplasms. Vulvar Neoplasms


8. LeRoy BE, Knight MC, Eggleston R, Torres-Velez F, Harmon BG: Tail-base mass from a "horse of a different color". Vet Clin Pathol; 2005;34(1):69-71
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The cytologic and histopathologic diagnoses were amelanotic melanoma.
  • In this report, we describe the cytopathologic features of an aggressive amelanotic melanoma in a non-grey horse and emphasize the unique correlation between cytologic and histologic findings.

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15732023.001).
  • [ISSN] 0275-6382
  • [Journal-full-title] Veterinary clinical pathology
  • [ISO-abbreviation] Vet Clin Pathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


9. Camerin M, Magaraggia M, Soncin M, Jori G, Moreno M, Chambrier I, Cook MJ, Russell DA: The in vivo efficacy of phthalocyanine-nanoparticle conjugates for the photodynamic therapy of amelanotic melanoma. Eur J Cancer; 2010 Jul;46(10):1910-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The in vivo efficacy of phthalocyanine-nanoparticle conjugates for the photodynamic therapy of amelanotic melanoma.
  • The efficiency of a Zn(II)-phthalocyanine disulphide (C11Pc), a compound with both phthalocyanine units bearing seven hexyl chains and a sulphur terminated C11 chain, as a photodynamic therapy (PDT) agent was investigated in C57 mice bearing a sub-cutaneously transplanted amelanotic melanoma.
  • Biodistribution studies at selected post-injection times showed that the nanoparticle-associated C11Pc was recovered in significantly larger amounts from all the examined tissues and the serum and yielded a greater selectivity of tumour targeting: thus, the ratio between the amount of phthalocyanine recovered from the amelanotic melanoma and the skin (peritumoural tissue) increased from 2.3 to 5.5 from the free to the gold nanoparticle-bound C11Pc at 24 h after injection.
  • PDT studies with the C11Pc-loaded amelanotic melanoma showed a markedly more significant response of the tumour in the mice that had received the nanoparticle-bound photosensitiser; the PDT effect was especially extensive if the irradiation was performed at 3h after C11Pc injection when large phthalocyanine amounts were still present in the serum.
  • [MeSH-major] Indoles / therapeutic use. Melanoma, Amelanotic / drug therapy. Metal Nanoparticles / therapeutic use. Organometallic Compounds / therapeutic use. Photochemotherapy / methods. Photosensitizing Agents / therapeutic use. Skin Neoplasms / drug therapy

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20356732.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / / C22031/A7097
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Indoles; 0 / Organometallic Compounds; 0 / Photosensitizing Agents; 14320-04-8 / Zn(II)-phthalocyanine
  •  go-up   go-down


10. Ohata Y, Haga T, Ogata S, Nakanishi K, Kawai T: Malignant amelanotic melanoma of the pleura without primary skin lesion:an autopsy case report. Acta Med Okayama; 2009 Dec;63(6):379-84
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant amelanotic melanoma of the pleura without primary skin lesion:an autopsy case report.
  • Melanoma metastasizing to the lungs is common, but primary pulmonary or pleural melanoma is extremely rare.
  • We present an autopsy case of malignant melanoma of the pleura without primary skin lesion in a 49-year-old man.
  • At autopsy, a yellow-white tumor located primarily in the right visceral pleura (diagnosed as an amelanotic melanoma) was found to have invaded into the right lung, right parietal pleura, and right diaphragm, and to have metastasized into the left lung and visceral pleura, thyroid, and left adrenal gland.
  • Immuno-histochemical examination for S100 and HMB-45 would thus appear to be useful for the diagnosis of an amelanotic melanoma.
  • [MeSH-major] Lung Neoplasms. Melanoma, Amelanotic. Pleura / pathology. Skin Neoplasms

  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20035295.001).
  • [ISSN] 0386-300X
  • [Journal-full-title] Acta medica Okayama
  • [ISO-abbreviation] Acta Med. Okayama
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


11. Tolleson WH, Doss JC, Latendresse J, Warbritton AR, Melchior WB Jr, Chin L, Dubielzig RR, Albert DM: Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice. Arch Ophthalmol; 2005 Aug;123(8):1088-94
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice.
  • OBJECTIVE: To characterize a murine model of spontaneous amelanotic melanoma arising in the uvea of transgenic mice bearing a targeted deletion of the Ink4a/Arf tumor suppressor locus (exons 2 and 3) and expressing human H-ras controlled by the human tyrosinase promoter.
  • RESULTS: Uveal melanomas were locally invasive but confined to the eye, with no evidence of metastasis.
  • The retinal pigment epithelium was intact above small melanomas, and electron microscopy of the tumors failed to show the presence of basement membrane formation or desmosomes.
  • CONCLUSION: Spontaneous uveal malignant melanomas occurring in male Tyr-RAS+ Ink4a/Arf-/- transgenic mice arise within the choroid or ciliary body and share histopathological features characteristic of human uveal melanoma.
  • CLINICAL RELEVANCE: Uveal melanoma research has benefited from xenograft models, but engineered mouse models of spontaneous uveal amelanotic melanoma will undoubtedly further our understanding of the genetic underpinning for this disease.
  • [MeSH-major] Cyclin-Dependent Kinase Inhibitor p16 / genetics. Gene Deletion. Genes, ras / genetics. Melanoma, Amelanotic / pathology. Monophenol Monooxygenase / genetics. Tumor Suppressor Protein p14ARF / genetics. Uveal Neoplasms / pathology
  • [MeSH-minor] Animals. Biomarkers, Tumor / analysis. Disease Models, Animal. Genotype. Male. Mice. Mice, Transgenic

  • COS Scholar Universe. author profiles.
  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16087843.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY 01917; United States / NCI NIH HHS / CA / R01 CA 93947
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cdkn2a protein, mouse; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Tumor Suppressor Protein p14ARF; EC 1.14.18.1 / Monophenol Monooxygenase
  •  go-up   go-down


12. Ashidi JS, Houghton PJ, Hylands PJ, Efferth T: Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from Cajanus cajan Millsp. leaves. J Ethnopharmacol; 2010 Mar 24;128(2):501-12
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • ETHNOPHARMACOLOGICAL RELEVANCE: There is only scant literature on the anticancer components of medicinal plants from Nigeria, yet traditional healers in the area under study claim to have been managing the disease in their patients with some success using the species studied.
  • Three cancer cell lines (human breast adenocarcinoma cell line MCF-7, human large cell lung carcinoma cell line COR-L23 and human amelanotic melanoma C32) and one normal cell line (normal human keratinocytes SVK-14) were used for the screening of the extracts and the fractions obtained.

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • COS Scholar Universe. author profiles.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20064598.001).
  • [ISSN] 1872-7573
  • [Journal-full-title] Journal of ethnopharmacology
  • [ISO-abbreviation] J Ethnopharmacol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Flavanones; 0 / Sitosterols; 0 / pinostrobin; 5LI01C78DD / gamma-sitosterol; 6SMK8R7TGJ / Oleanolic Acid; KM8353IPSO / amyrin
  •  go-up   go-down


13. Zamberk-Majlis P, Velázquez-Tarjuelo D, Avilés-Izquierdo JA, Lázaro-Ochaita P: [Dermoscopic characterization of 3 cases of fibroepithelioma of Pinkus]. Actas Dermosifiliogr; 2009 Dec;100(10):899-902
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Clinical diagnosis often requires differentiation from benign lesions such as acrochordon, intradermal melanocytic nevus, neurofibroma, seborrheic keratosis, and even malignant lesions such as amelanotic melanoma.

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20038369.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


14. Samaila MO, Mbibu HN, Oluwole OP: Human mycetoma. Surg Infect (Larchmt); 2007 Oct;8(5):519-22
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, the disease may present without these characteristic features, thus causing diagnostic difficulty with other chronic granulomatous infections such as tuberculosis or benign skin lesions.
  • The range of clinical misdiagnoses included skin tuberculosis, fibroma, amelanotic melanoma, basal-cell carcinoma, and brain tumor.
  • CONCLUSION: Mycetoma is a disease with sporadic occurrence in our environment.

  • Genetic Alliance. consumer health - Mycetoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17999585.001).
  • [ISSN] 1096-2964
  • [Journal-full-title] Surgical infections
  • [ISO-abbreviation] Surg Infect (Larchmt)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. Chen KG, Szakács G, Annereau JP, Rouzaud F, Liang XJ, Valencia JC, Nagineni CN, Hooks JJ, Hearing VJ, Gottesman MM: Principal expression of two mRNA isoforms (ABCB 5alpha and ABCB 5beta ) of the ATP-binding cassette transporter gene ABCB 5 in melanoma cells and melanocytes. Pigment Cell Res; 2005 Apr;18(2):102-12
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Principal expression of two mRNA isoforms (ABCB 5alpha and ABCB 5beta ) of the ATP-binding cassette transporter gene ABCB 5 in melanoma cells and melanocytes.
  • We identified and cloned two novel mRNA isoforms (ABCB 5alpha and ABCB 5beta) of the ABC transporter ABCB 5 in human melanoma cells.
  • We found that the melanomas included among the NCI-60 panel of cell lines preferentially expressed both ABCB 5alpha and ABCB 5beta.
  • However, ABCB 5alpha/beta expression was undetectable in two amelanotic melanomas (M14 and LOX-IMVI).
  • The expression profile of ABCB 5alpha/beta in all of the other melanomas of the panel was confirmed both by RT-PCR and by sequencing.
  • Our findings indicate that expression of ABCB 5alpha/beta might possibly provide two novel molecular markers for differential diagnosis of melanomas and constitute potential molecular targets for therapy of melanomas.

  • COS Scholar Universe. author profiles.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nat Genet. 2000 Mar;24(3):227-35 [10700174.001]
  • [Cites] Nat Genet. 2000 Mar;24(3):236-44 [10700175.001]
  • [Cites] J Biol Chem. 2000 Jun 9;275(23):17536-40 [10837493.001]
  • [Cites] J Lipid Res. 2001 Jul;42(7):1007-17 [11441126.001]
  • [Cites] Pigment Cell Res. 2001 Aug;14(4):289-97 [11549113.001]
  • [Cites] J Bioenerg Biomembr. 2001 Dec;33(6):475-9 [11804189.001]
  • [Cites] Nat Rev Cancer. 2002 Jan;2(1):48-58 [11902585.001]
  • [Cites] Annu Rev Biochem. 2002;71:537-92 [12045106.001]
  • [Cites] Mol Pathol. 2002 Oct;55(5):294-9 [12354931.001]
  • [Cites] Clin Chem. 2003 Feb;49(2):230-8 [12560344.001]
  • [Cites] J Biol Chem. 2003 Nov 21;278(47):47156-65 [12960149.001]
  • [Cites] Curr Drug Metab. 2004 Feb;5(1):21-53 [14965249.001]
  • [Cites] Cancer Res. 2004 Jun 15;64(12):4294-301 [15205344.001]
  • [Cites] Cancer Cell. 2004 Aug;6(2):129-37 [15324696.001]
  • [Cites] Annu Rev Microbiol. 2004;58:303-28 [15487940.001]
  • [Cites] Cancer Res. 1985 Sep;45(9):4091-6 [4028002.001]
  • [Cites] J Biol Chem. 1986 Jun 15;261(17):7762-70 [3711108.001]
  • [Cites] Proc Natl Acad Sci U S A. 1987 Jan;84(1):265-9 [2432605.001]
  • [Cites] Proc Natl Acad Sci U S A. 1987 Nov;84(21):7735-8 [2444983.001]
  • [Cites] J Histochem Cytochem. 1990 Sep;38(9):1277-87 [1974900.001]
  • [Cites] Cell. 1991 Jul 12;66(1):85-94 [1712673.001]
  • [Cites] Cancer Res. 1994 Sep 15;54(18):4980-7 [7915196.001]
  • [Cites] Cancer Res. 1995 May 15;55(10):2029-34 [7538046.001]
  • [Cites] Clin Diagn Lab Immunol. 1994 Sep;1(5):569-77 [8556503.001]
  • [Cites] Nat Genet. 1997 Mar;15(3):236-46 [9054934.001]
  • [Cites] Melanoma Res. 1997 Apr;7(2):83-95 [9167173.001]
  • [Cites] Nat Genet. 1999 Aug;22(4):347-51 [10431237.001]
  • [Cites] J Biol Chem. 1998 Apr 17;273(16):10046-50 [9545351.001]
  • (PMID = 15760339.001).
  • [ISSN] 0893-5785
  • [Journal-full-title] Pigment cell research
  • [ISO-abbreviation] Pigment Cell Res.
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / / Z99 NS999999
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / ABCB5 protein, human; 0 / Biomarkers, Tumor; 0 / P-Glycoprotein; 0 / RNA, Messenger
  • [Other-IDs] NLM/ NIHMS318566; NLM/ PMC3915408
  •  go-up   go-down


16. Wain EM, Stefanato CM, Barlow RJ: A clinicopathological surprise: amelanotic malignant melanoma. Clin Exp Dermatol; 2008 May;33(3):365-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A clinicopathological surprise: amelanotic malignant melanoma.
  • [MeSH-major] Melanocytes / pathology. Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18419612.001).
  • [ISSN] 0307-6938
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 6
  •  go-up   go-down


17. Zalaudek I, Kreusch J, Giacomel J, Ferrara G, Catricalà C, Argenziano G: How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part II. Nonmelanocytic skin tumors. J Am Acad Dermatol; 2010 Sep;63(3):377-86; quiz 387-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In contrast to the rarity of amelanotic melanoma, nonmelanoma skin cancer commonly lacks pigmentation.
  • Dermoscopic vascular patterns of several nonmelanocytic nonpigmented skin tumors, such as sebaceous hyperplasia, seborrheic keratosis, clear cell acanthoma, Bowen disease, or nodular cystic basal cell carcinoma are highly specific, allowing a ready diagnosis in most cases.
  • In the second part of this review of dermoscopic vascular structures of nonpigmented skin tumors, the dermoscopic patterns associated with benign and malignant nonmelanocytic skin tumors and recommendations for the management of these tumors will be discussed.
  • [MeSH-minor] Blood Vessels / pathology. Bowen's Disease / blood supply. Bowen's Disease / diagnosis. Bowen's Disease / pathology. Carcinoma, Basal Cell / blood supply. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / pathology. Carcinoma, Squamous Cell / blood supply. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Education, Medical, Continuing. Female. Humans. Keratosis, Seborrheic / diagnosis. Keratosis, Seborrheic / pathology. Male. Melanoma, Amelanotic / blood supply. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / pathology


18. de Koning HD, Bovenschen HJ: Two adjacent nodules on the leg. Dermatol Online J; 2010;16(6):13
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Poroma is a rare benign neoplasm (derived from the intraepidermal part of the eccrine or apocrine duct), which may clinically mimic malignant tumors such as (amelanotic) malignant melanoma and porocarcinoma.
  • Despite a clinical differential diagnosis of melanoma, histopathology showed the typical characteristics of a poroma, a rare but much more favorable tumor.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20579468.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


19. Cichorek M, Kozłowska K, Bryl E: The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell. Cancer Biol Ther; 2007 Mar;6(3):346-53
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell.
  • Loss of pigment in hamster amelanotic melanoma line is accompanied by a faster growth rate, higher tumorigenicity and shorter animal survival time.
  • Thus, the malignancy of melanoma increases during the alteration of melanotic (Ma) into amelanotic (Ab) line.
  • As changes in the ability to undergo a spontaneous or induced apoptosis, and the role of caspases in this process during melanoma progression are not well defined, they were investigated in this work.
  • Cytochrome c release into cytosol, and the activation of effector caspases, estimated by PARP degradation clearly showed that during the spontaneous death in the cells from both melanoma lines intrinsic way of apoptosis was activated.
  • Confocal and cytometric flow analyses indicate that camptothecin (CPT) induced apoptosis with caspase activation by the intrinsic way only in the amelanotic melanoma cells, even though cells of the Ma line also underwent CPT-induced apoptosis (the content of TUNEL-positive cells increased).
  • Thus, our results suggest that melanoma progression, associated with a decreased ability to undergo spontaneous apoptosis but an increased susceptibility to CPT-induced apoptosis, relates to different levels of caspase activation; they also show that intrinsic way of apoptotis depends on the phenotype of melanoma cells, being more pronounced in the melanotic melanoma cells.
  • On the other hand, melanotic melanoma cells resistance to camptothecin-induced apoptosis suggests that the melanogenic apparatus or melanin itself may have the protective effect on the ability of the melanoma cells to undergo apoptosis.
  • [MeSH-major] Apoptosis. Caspases / metabolism. Melanoma, Amelanotic / enzymology. Melanoma, Experimental / enzymology. Skin Neoplasms / enzymology
  • [MeSH-minor] Animals. Antineoplastic Agents / toxicity. Camptothecin / toxicity. Cell Line, Tumor. Cricetinae. Cytochromes c / metabolism. Disease Progression. Flow Cytometry. Male. Melanins / metabolism. Mesocricetus. Microscopy, Confocal. Poly(ADP-ribose) Polymerases / metabolism

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17312383.001).
  • [ISSN] 1538-4047
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Melanins; 9007-43-6 / Cytochromes c; EC 2.4.2.30 / Poly(ADP-ribose) Polymerases; EC 3.4.22.- / Caspases; XT3Z54Z28A / Camptothecin
  •  go-up   go-down


20. Avilés-Izquierdo JA, Velázquez-Tarjuelo D, Lecona-Echevarría M, Lázaro-Ochaita P: [Dermoscopic features of eccrine poroma]. Actas Dermosifiliogr; 2009 Mar;100(2):133-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eccrine poroma is a benign adnexal neoplasm that clinically may mimic malignant skin tumors such as squamous cell carcinoma and amelanotic melanoma.

  • MedlinePlus Health Information. consumer health - Foot Injuries and Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19445878.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


21. Camerin M, Rodgers MA, Kenney ME, Jori G: Photothermal sensitisation: evidence for the lack of oxygen effect on the photosensitising activity. Photochem Photobiol Sci; 2005 Mar;4(3):251-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Irradiation of amelanotic melanoma B78H1 cells in the presence of liposome-delivered Ni(II)-octabutoxy-naphthalocyanine with a Q-switched Ti:sapphire laser operated in a pulsed mode (850 nm, 30 ns pulses, 10 Hz, 120 mJ pulse -1) promotes a photothermal sensitization process leading to extensive cell inactivation.
  • [MeSH-minor] Air. Animals. Cell Line, Tumor. Lasers. Melanoma, Experimental / drug therapy. Metalloporphyrins / therapeutic use. Mice. Nitrogen. Time Factors

  • Hazardous Substances Data Bank. Nitrogen, Elemental .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15738991.001).
  • [ISSN] 1474-905X
  • [Journal-full-title] Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
  • [ISO-abbreviation] Photochem. Photobiol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Metalloporphyrins; 0 / octabutoxynaphthalocyaninenickel(II); N762921K75 / Nitrogen
  •  go-up   go-down


22. Chun JK, Singer E, Kong A, Phelps R, Weltz C: Desmoplastic amelanotic melanoma in an irradiated burn scar. Dermatol Surg; 2006 Jan;32(1):161-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic amelanotic melanoma in an irradiated burn scar.
  • [MeSH-major] Burns / complications. Cicatrix / complications. Cicatrix / radiotherapy. Melanoma, Amelanotic / etiology. Skin Neoplasms / etiology

  • MedlinePlus Health Information. consumer health - Burns.
  • MedlinePlus Health Information. consumer health - Scars.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16393619.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


23. André J, Moulonguet I, Goettmann-Bonvallot S: In situ amelanotic melanoma of the nail unit mimicking lichen planus: report of 3 cases. Arch Dermatol; 2010 Apr;146(4):418-21
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] In situ amelanotic melanoma of the nail unit mimicking lichen planus: report of 3 cases.
  • BACKGROUND: Nail apparatus melanoma is known to be associated with a poor prognosis, mainly because of a delay in diagnosis that is made at an invasive stage.
  • This delay is particularly true in cases involving amelanotic melanoma.
  • To our knowledge, only 1 case of in situ amelanotic melanoma of the nail unit has previously been described.
  • We report 3 cases of in situ amelanotic melanoma with clinical lichenoid features.
  • OBSERVATIONS: We describe 3 cases of in situ amelanotic melanoma of the nail unit.
  • Histologic examination revealed in situ amelanotic melanoma extending from the proximal matrix up to the distal part of the nail bed.
  • CONCLUSIONS: Monodactylic lichenoid nail changes should be added to the more conventional signs of incipient nail melanoma.
  • [MeSH-major] Lichen Planus / diagnosis. Melanoma, Amelanotic / diagnosis. Nail Diseases / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Nail Diseases.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20404232.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


24. Lin JY, Liu D, Li EJ: [Clinical and pathological features of 26 cases of conjunctival melanoma]. Zhonghua Yan Ke Za Zhi; 2010 Apr;46(4):308-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical and pathological features of 26 cases of conjunctival melanoma].
  • OBJECTIVE: To improve the knowledge of clinical and pathological features of conjunctival melanoma, in order to have an early diagnosis and treatment.
  • The clinical and pathological features of 26 cases of conjunctival melanoma were analyzed.
  • Twenty two cases were epitheloid-cell-type melanoma, 4 cases were mixed-cell-type melanoma.
  • There were 3 amelanotic melanomas, the tumor cells were positively stained with S-100 and HMB-45.
  • CONCLUSIONS: Conjunctival melanoma mainly arises from malignant transformation of PAM or conjunctival nevi and consists of epitheloid melanotic tumor cells.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Melanoma / pathology

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20654056.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


25. Altamura D, Piccolo D, Lozzi GP, Peris K: Eccrine poroma in an unusual site: a clinical and dermoscopic simulator of amelanotic melanoma. J Am Acad Dermatol; 2005 Sep;53(3):539-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eccrine poroma in an unusual site: a clinical and dermoscopic simulator of amelanotic melanoma.
  • [MeSH-major] Acrospiroma / diagnosis. Dermoscopy. Melanoma, Amelanotic / diagnosis. Skin Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16112378.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  •  go-up   go-down


26. de Giorgi V, Sestini S, Massi D, Maio V, Giannotti B: Dermoscopy for "true" amelanotic melanoma: a clinical dermoscopic-pathologic case study. J Am Acad Dermatol; 2006 Feb;54(2):341-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermoscopy for "true" amelanotic melanoma: a clinical dermoscopic-pathologic case study.
  • Completely amelanotic melanomas are rare and therefore often misclassified, with tragic consequences for patients.
  • We present a case of "true" amelanotic melanoma on the forehead of an 89-year-old man, which clinically mimicked squamous cell carcinoma.
  • The dermoscopic diagnostic algorithms routinely used for pigmented lesions are not helpful in diagnosing amelanotic melanoma because they are based on specific parameters not normally seen in amelanotic lesions.
  • In the light of our experience, pattern analysis is the most reliable method for diagnosing these particular lesions correctly because it allows in-depth morphologic analysis of the few parameters found.
  • [MeSH-major] Dermoscopy. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Am Acad Dermatol. 2006 Oct;55(4):728 [17010767.001]
  • (PMID = 16443072.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


27. Pietzner K, Noske A, Cho CH, Kiecker F, Sehouli J: Amelanotic metastasis of melanoma mimicking ovarian cancer: a case report and review of the literature. Anticancer Res; 2008 Jan-Feb;28(1B):563-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic metastasis of melanoma mimicking ovarian cancer: a case report and review of the literature.
  • Ovarian manifestation of metastatic amelanotic melanoma is exceptionally rare and can lead to the clinical and even histological misdiagnosis of ovarian cancer.
  • She was histologically diagnosed with malignant ovarian tumour and was referred for radical surgery.
  • Postoperative final histological examination and immunohistochemical staining of the tumour revealed an amelanotic epithelioid melanoma.
  • This report discusses the differential diagnosis and clinical management of both metastatic amelanotic malignant melanoma of the ovary and epithelial ovarian cancer.
  • [MeSH-major] Melanoma, Amelanotic / secondary. Ovarian Neoplasms / diagnosis. Skin Neoplasms / secondary

  • Genetic Alliance. consumer health - Ovarian cancer.
  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18383903.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


28. Tundis R, Loizzo MR, Bonesi M, Menichini F, Dodaro D, Passalacqua NG, Statti G, Menichini F: In vitro cytotoxic effects of Senecio stabianus Lacaita (Asteraceae) on human cancer cell lines. Nat Prod Res; 2009;23(18):1707-18
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This study is aimed to evaluate the in vitro cytotoxicity of Senecio stabianus Lacaita (Asteraceae) against renal adenocarcinoma ACHN, hormone-dependent prostate carcinoma LNCaP, amelanotic melanoma C32 and human breast adenocarcinoma MCF-7 cell lines.

  • Hazardous Substances Data Bank. N-HEXANE .
  • Hazardous Substances Data Bank. LINALOOL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19921589.001).
  • [ISSN] 1478-6427
  • [Journal-full-title] Natural product research
  • [ISO-abbreviation] Nat. Prod. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hexanes; 0 / Monoterpenes; 0 / Plant Extracts; 0 / Pyrrolizidine Alkaloids; 0 / Sesquiterpenes; 2DDG612ED8 / n-hexane; 54W56MD2WD / humulene; BHW853AU9H / caryophyllene; D81QY6I88E / linalool
  •  go-up   go-down


29. Camerin M, Rello-Varona S, Villanueva A, Rodgers MA, Jori G: Metallo-naphthalocyanines as photothermal sensitisers for experimental tumours: in vitro and in vivo studies. Lasers Surg Med; 2009 Nov;41(9):665-73
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • STUDY DESIGN/MATERIALS AND METHODS: Two octabutoxy-naphthalocyanines centrally coordinated with Pd(II) or Pt(II) ions were prepared by chemical synthesis and tested for their affinity and photothermal sensitisation activity toward a selected tumour cell line, namely B78H1 amelanotic melanoma.
  • The results thus obtained provided a basis for subsequent in vivo studies, aimed at defining the phototherapeutic efficiency of the two metallo-naphthalocyanines: the photosensitisers were i.v. injected into C57BL/6 mice bearing a subcutaneously transplanted amelanotic melanoma and at 24 hours post-injection the tumour area was irradiated by the Ti:sapphire laser using the same protocol as above detailed.
  • RESULTS: Both naphthalocyanines exhibited a high affinity for the amelanotic melanoma cells.
  • Lastly, both metallo-naphthalocyanines, and in particular the Pd(II) derivative, promoted an important response by the amelanotic melanoma, when the neoplastic tissue was irradiated by the pulsed Ti:sapphire laser.
  • [MeSH-major] Laser Therapy. Melanoma, Amelanotic / radiotherapy. Metalloporphyrins / therapeutic use. Organometallic Compounds / therapeutic use. Photochemotherapy / methods. Skin Neoplasms / radiotherapy

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • Hazardous Substances Data Bank. PALLADIUM, ELEMENTAL .
  • Hazardous Substances Data Bank. PLATINUM .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 Wiley-Liss, Inc.
  • (PMID = 19790243.001).
  • [ISSN] 1096-9101
  • [Journal-full-title] Lasers in surgery and medicine
  • [ISO-abbreviation] Lasers Surg Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Metalloporphyrins; 0 / Organometallic Compounds; 0 / palladium 5,9,14,18,23,27,32,36-octabutoxynaphthalocyanine; 49DFR088MY / Platinum; 5TWQ1V240M / Palladium
  •  go-up   go-down


30. Gao N, Li LJ, Li Y, Wang L: Primary amelanotic malignant melanoma of the parotid gland: a case report. J Int Med Res; 2008 Nov-Dec;36(6):1435-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic malignant melanoma of the parotid gland: a case report.
  • Amelanotic malignant melanoma in the oral region is extremely rare and has not previously been reported in the parotid gland.
  • This present case report describes an amelanotic malignant melanoma in the parotid gland, with no other primary lesion detectable.
  • Amelanotic malignant melanoma is a melanoma subtype with little or no pigmentation and, because of this lack of pigmentation and its wide-ranging clinical appearance, it often defies clinical diagnosis.
  • Where it is suspected, positive expression of S-100 protein and human melanoma black 45(HMB45) using immunohistochemical analysis can be considered reliable methods of confirming diagnosis.
  • [MeSH-major] Melanoma, Amelanotic / secondary. Parotid Gland / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Fatal Outcome. Humans. Lymph Nodes / pathology. Male. Melanoma-Specific Antigens. Neoplasm Proteins / analysis. S100 Proteins / analysis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19094455.001).
  • [ISSN] 0300-0605
  • [Journal-full-title] The Journal of international medical research
  • [ISO-abbreviation] J. Int. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  •  go-up   go-down


31. Klopper JP, Sharma V, Bissonnette R, Haugen BR: Combination PPARgamma and RXR Agonist Treatment in Melanoma Cells: Functional Importance of S100A2. PPAR Res; 2010;2010:729876
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combination PPARgamma and RXR Agonist Treatment in Melanoma Cells: Functional Importance of S100A2.
  • Nuclear hormone receptors, including RXR and PPARgamma, represent novel therapeutic targets in melanoma.
  • We have previously shown that the DRO subline of the amelanotic melanoma A375 responds to rexinoid and thiazolidinedione (TZD) treatment in vitro and in vivo.
  • In summary, we have identified potential downstream mediators of rexinoid and TZD treatment in a poorly differentiated melanoma and found that alterations in S100A2 expression affect RXR and PPARgamma signaling in A375(DRO) cells.

  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Clin Endocrinol Metab. 2008 Nov;93(11):4331-41 [18713817.001]
  • [Cites] J Cutan Pathol. 2008 Nov;35(11):1014-9 [18547346.001]
  • [Cites] Onkologie. 2008 Jul;31(7):380-4 [18596385.001]
  • [Cites] Cancer Invest. 2008 Jul;26(6):624-33 [18584354.001]
  • [Cites] Exp Dermatol. 2008 May;17(5):383-94 [18312390.001]
  • [Cites] Eur J Surg Oncol. 2008 Apr;34(4):357-64 [17566693.001]
  • [Cites] Clin Cancer Res. 2008 Jan 15;14(2):589-96 [18223235.001]
  • [Cites] Clin Cancer Res. 2007 Sep 1;13(17):5219-25 [17785578.001]
  • [Cites] Eur J Cancer. 2007 Sep;43(13):1935-43 [17689067.001]
  • [Cites] Melanoma Res. 2007 Apr;17(2):117-27 [17496787.001]
  • [Cites] Cancer Res. 2006 Dec 15;66(24):12009-18 [17178900.001]
  • [Cites] Cell Mol Life Sci. 2006 Oct;63(19-20):2387-96 [16988787.001]
  • [Cites] J Biol Chem. 2005 Aug 12;280(32):29186-93 [15941720.001]
  • [Cites] Cell Differ. 1987 Jul;21(2):137-45 [3308117.001]
  • [Cites] Mol Cancer Ther. 2004 Aug;3(8):1011-20 [15299084.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Jan;89(1):272-80 [14715861.001]
  • [Cites] J Biomed Sci. 2003 May-Jun;10(3):313-9 [12711858.001]
  • [Cites] Genetics. 2003 Mar;163(3):1047-60 [12663543.001]
  • [Cites] J Biol Chem. 2001 Jun 22;276(25):22699-708 [11278647.001]
  • (PMID = 19859558.001).
  • [ISSN] 1687-4765
  • [Journal-full-title] PPAR research
  • [ISO-abbreviation] PPAR Res
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA100560
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2763133
  •  go-up   go-down


32. Seya T, Tanaka N, Shinji S, Shinji E, Yokoi K, Horiba K, Kanazawa Y, Yamada T, Oaki Y, Tajiri T: Case of rectal malignant melanoma showing immunohistochemical variability in a tumor. J Nippon Med Sch; 2007 Oct;74(5):377-81
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case of rectal malignant melanoma showing immunohistochemical variability in a tumor.
  • We report on a patient with rectal malignant melanoma.
  • However, the final pathological diagnosis of the surgically resected specimen was malignant amelanotic melanoma of the rectum.
  • However, there were no anticancer drugs tested by CD-DST for malignant melanoma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Melanoma / diagnosis. Neoplasm Proteins / analysis. Proto-Oncogene Proteins c-kit / analysis. Rectal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Antigens, Neoplasm. Antineoplastic Combined Chemotherapy Protocols / pharmacology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Digestive System Surgical Procedures. Drug Resistance, Neoplasm. Drug Screening Assays, Antitumor / methods. Fatal Outcome. Humans. Immunohistochemistry. Interferon-beta / administration & dosage. Male. Melanoma-Specific Antigens. Neoadjuvant Therapy. Tumor Cells, Cultured

  • MedlinePlus Health Information. consumer health - Melanoma.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17965534.001).
  • [ISSN] 1345-4676
  • [Journal-full-title] Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
  • [ISO-abbreviation] J Nippon Med Sch
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 77238-31-4 / Interferon-beta; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  •  go-up   go-down


33. Mensing C, Livingstone E, Schwarz T, Hauschild A: Eczematous malignant melanoma: a wolf in sheep's clothing. Onkologie; 2009 Apr;32(4):206-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eczematous malignant melanoma: a wolf in sheep's clothing.
  • BACKGROUND: The clinical diagnosis of amelanotic melanoma is still a challenge.
  • CASE REPORT: A 72-year-old patient was first referred to us for the excision of a melanoma of the chin.
  • In the first examination, we discovered another melanoma of the trunk.
  • Both malignancies were excised and histopathology confirmed the clinical diagnosis of melanomas with Clark level II and III, respectively.
  • Apart from these melanomas, physical examination revealed an 8 cm x 5 cm large erythematous plaque on the left upper arm.
  • Surprisingly, the pathology report showed typical features of a malignant melanoma.
  • CONCLUSIONS: Amelanotic melanoma may appear as an erythematous macula or plaque; clinical symptoms are erythema, edema, pruritus or a slow increase in size and hypopigmentation or discoloration.
  • [MeSH-major] Eczema / diagnosis. Eczema / etiology. Melanoma / complications. Melanoma / diagnosis. Skin Neoplasms / complications. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Eczema.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19372718.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


34. Hillenbrand A, Barth TF, Henne-Bruns D, Formentini A: Anorectal amelanotic melanoma. Colorectal Dis; 2008 Jul;10(6):612-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal amelanotic melanoma.
  • OBJECTIVE: Anorectal melanoma is a rare, highly malignant tumour with a poor 5 year survival of 10%.
  • Most anorectal melanomas have gross and/or histologic pigmentation, however about 30% of anorectal melanomas are amelanotic.
  • METHOD: We report three cases of amelanotic anorectal melanomas and integrate our data with six case reports of amelanotic malignant melanoma from the literature.
  • Further we compare clinicopathological data and clinical outcome with large series of anorectal melanomas (both, amelanotic and pigmentated).
  • A tumour thickness of < 4 mm was correlated with long-term disease-free survival, whereas tumour thickness of 4 mm or more was correlated with systemic recurrence.
  • CONCLUSION: Early diagnosis is key for efficient treatment and improved survival rate for patients with this unusual variant of melanoma.
  • There is no difference in terms of age, time of diagnosis, stage and survival between pigmented and amelanotic anorectal melanoma.
  • [MeSH-major] Anus Neoplasms. Melanoma, Amelanotic. Rectal Neoplasms

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17944970.001).
  • [ISSN] 1463-1318
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  •  go-up   go-down


35. Mercadier B, Hu W, Valentin S, Sassolas B: [Amelanotic malignant melanoma: about three cases]. Ann Chir Plast Esthet; 2007 Feb;52(1):68-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Amelanotic malignant melanoma: about three cases].
  • [Transliterated title] Mélanome malin achromique : à propos de trois cas.
  • The amelanotic melanoma is a rare type of malignant melanoma.
  • The purpose of this report is to point out this aspect of melanoma, whose diagnostic delay is frequent.
  • We describe one localisation on the penis, rare in this kind of melanoma and two cases of the extremities, more frequent localization of the amelanotic melanoma.
  • The therapeutic issues and recommendation are similar to the classical pigmented malignant melanoma.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17030390.001).
  • [ISSN] 0294-1260
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


36. Wang S, Thamboo TP, Nga ME, Zin T, Cheng A, Tan KB: C-kit positive amelanotic melanoma of the oesophagus: a potential diagnostic pitfall. Pathology; 2008 Aug;40(5):527-30
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] C-kit positive amelanotic melanoma of the oesophagus: a potential diagnostic pitfall.
  • [MeSH-major] Esophageal Neoplasms / metabolism. Esophageal Neoplasms / pathology. Melanoma, Amelanotic / metabolism. Proto-Oncogene Proteins c-kit / biosynthesis

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18604743.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  •  go-up   go-down


37. Kusick S, Bertram H, Oberleithner H, Ludwig T: Nanoscale imaging and quantification of local proteolytic activity. J Cell Physiol; 2005 Sep;204(3):767-74
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Malignant cells secrete most proteases as inactive proenzymes that undergo proteolytic cleavage for activation, and proteolytic activity is elevated in close proximity to these cells.
  • Amelanotic melanoma cells (A7-clone) were seeded on fluorescent gelatin or collagen-IV coatings.

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 15744770.001).
  • [ISSN] 0021-9541
  • [Journal-full-title] Journal of cellular physiology
  • [ISO-abbreviation] J. Cell. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Proteins; EC 3.4.- / Peptide Hydrolases
  •  go-up   go-down


38. Jain V, Dabir S, Shome D, Dadu T, Natarajan S: Aspergillus iris granuloma: a case report with review of literature. Surv Ophthalmol; 2009 Mar-Apr;54(2):286-91
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Differential diagnoses of a fungal granuloma, a medulloepithelioma, and an amelanotic melanoma were considered.
  • Definitive differentiation of this rare entity from a foreign body, amelanotic melanoma, and other inflammatory conditions such as sarcoidosis and tuberculosis, may be possible only on microbiological and histo-pathological evaluation.

  • MedlinePlus Health Information. consumer health - Aspergillosis.
  • Hazardous Substances Data Bank. ATROPINE .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19298905.001).
  • [ISSN] 0039-6257
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antifungal Agents; 0 / Aza Compounds; 0 / DNA, Fungal; 0 / Fluoroquinolones; 0 / Quinolines; 7C0697DR9I / Atropine; 8O0C852CPO / Natamycin; U188XYD42P / moxifloxacin
  • [Number-of-references] 18
  •  go-up   go-down


39. Conforti F, Ioele G, Statti GA, Marrelli M, Ragno G, Menichini F: Antiproliferative activity against human tumor cell lines and toxicity test on Mediterranean dietary plants. Food Chem Toxicol; 2008 Oct;46(10):3325-32
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sixteen edible plants from Southern Italy were evaluated for their in vitro antiproliferative properties, using the sulforodamine B (SRB) assay, on four human cancer cell lines: breast cancer MCF-7, prostate cancer LNCaP, amelanotic melanoma C32 and renal adenocarcinoma ACHN.
  • Mentha aquatica showed a selective antiproliferative activity on breast cancer while significant activity was exerted by Cichorium intybus on melanoma.

  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18768152.001).
  • [ISSN] 0278-6915
  • [Journal-full-title] Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • [ISO-abbreviation] Food Chem. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Plant Extracts
  •  go-up   go-down


40. Blum A: [Therapy of amelanotic melanoma]. Dtsch Med Wochenschr; 2005 May 20;130(20):1277
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Therapy of amelanotic melanoma].
  • [MeSH-major] Melanoma, Amelanotic / therapy. Skin Neoplasms / therapy

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15889328.001).
  • [ISSN] 0012-0472
  • [Journal-full-title] Deutsche medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Dtsch. Med. Wochenschr.
  • [Language] ger
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


41. Pirenne Y, Bouckaert W, Vangertruyden G: Rectal melanoma--a rare tumour. Acta Chir Belg; 2008 Nov-Dec;108(6):756-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rectal melanoma--a rare tumour.
  • Malignant rectal melanoma is a rare tumour.
  • Biopsies proved it to be an amelanotic malignant melanoma, as protein S100, melanoma antigen HMB45 and Melan-A expression were found.
  • Histology confirmed an amelanotic malignant melanoma.
  • With this case we want to illustrate that malignant rectal melanoma can be difficult to diagnose, as patients have non-specific symptoms, and histology may be misleading.
  • One should always check for protein S-100, melanoma antigen HMN-45 and Melan-A expression, as they are strongly suggestive of melanoma.
  • Rectal melanoma has a poor outcome with a 5-year survival rate of between 10-20%.
  • The extent of the disease correlates with the overall survival.
  • [MeSH-major] Melanoma, Amelanotic / surgery. Rectal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19241934.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
  •  go-up   go-down


42. Ishii H, Joshita T, Matsuyama N, Uchida T, Ishikawa A, Ebihara Y: Immunohistochemical and ultrastructural investigation on cutaneous neuroendocrine carcinoma: report of a case and review of the literature. Med Mol Morphol; 2006 Sep;39(3):164-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a tumor in an 80-year-old man that was difficult to distinguish from other tumors, i.e., small cell carcinoma of the lung, PNET/Ewing tumor, malignant lymphoma, or malignant melanoma (amelanotic), and which was finally identified as cutaneous neuroendocrine carcinoma using immunohistochemical and ultrastructural methods.
  • Immunohistochemistry tests gave negative results for LCA, UCHL-1, CD3, and CD20, thereby excluding malignant lymphoma, and the negative results for S-100 protein and HMB-45 ruled out malignant melanoma.

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Histopathology. 1992 May;20(5):437-9 [1587495.001]
  • [Cites] Am J Dermatopathol. 1982 Dec;4(6):497-500 [7165057.001]
  • [Cites] Am J Dermatopathol. 1999 Feb;21(1):16-20 [10027519.001]
  • [Cites] J Surg Oncol. 2005 Jan 1;89(1):5 [15611999.001]
  • [Cites] Dermatol Surg. 2000 Sep;26(9):853-6 [10971559.001]
  • [Cites] Am J Ophthalmol. 1992 Jun 15;113(6):674-80 [1598958.001]
  • [Cites] J Clin Pathol. 2001 Sep;54(9):727-9 [11533085.001]
  • [Cites] Am J Dermatopathol. 1996 Jun;18(3):273-7 [8806961.001]
  • [Cites] J Am Acad Dermatol. 1997 Nov;37(5 Pt 1):734-9 [9366819.001]
  • [Cites] Ann Surg. 1999 Jan;229(1):97-105 [9923806.001]
  • [Cites] Arch Dermatol. 1972 Jan;105(1):107-10 [5009611.001]
  • [Cites] Handchir Mikrochir Plast Chir. 1996 Jan;28(1):43-5 [8852641.001]
  • [Cites] Am J Clin Oncol. 2004 Dec;27(6):576-83 [15577435.001]
  • [Cites] J Eur Acad Dermatol Venereol. 2002 Jan;16(1):82-3 [11952300.001]
  • [Cites] Ultrastruct Pathol. 2005 May-Aug;29(3-4):287-94 [16036883.001]
  • [Cites] J Cutan Pathol. 1986 Oct;13(5):347-58 [2946733.001]
  • [Cites] J Surg Oncol. 2005 Jan 1;89(1):1-4 [15611998.001]
  • (PMID = 16998628.001).
  • [ISSN] 1860-1480
  • [Journal-full-title] Medical molecular morphology
  • [ISO-abbreviation] Med Mol Morphol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


43. Ladoyanni E, Abdullah A, Sterne GD, Zaki I: Amelanotic melanoma--"to be or not to be". Acta Derm Venereol; 2006;86(2):189-90
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic melanoma--"to be or not to be".
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16648938.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Norway
  •  go-up   go-down


44. Dickinson RM, Young KM: Cutaneous mass aspirate from a Golden Retriever: "glandular guile". Vet Clin Pathol; 2005 Dec;34(4):421-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • On cytologic evaluation of a fine-needle aspirate of the mass, the interpretation was a malignant tumor with predominantly mesenchymal features.
  • Differentials included liposarcoma, atypical amelanotic melanoma, anaplastic sarcoma, and anaplastic carcinoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16270273.001).
  • [ISSN] 0275-6382
  • [Journal-full-title] Veterinary clinical pathology
  • [ISO-abbreviation] Vet Clin Pathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 68238-35-7 / Keratins
  •  go-up   go-down


45. Roy S, Dhingra K, Mandal S, Khurana N: Unusual presentation of metastatic amelanotic melanoma of unknown primary origin as a solitary breast lump. Melanoma Res; 2008 Dec;18(6):447-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual presentation of metastatic amelanotic melanoma of unknown primary origin as a solitary breast lump.
  • Breast is an uncommon site for metastasis from other malignancies especially melanomas.
  • Immunoreactivity for S-100 and HMB-45, confirmed the diagnosis of amelanotic melanoma.
  • It is important to be aware of this atypical presentation of amelanotic melanoma in the breast and to utilize immunohistochemistry to differentiate from other commoner high-grade malignant tumors.
  • [MeSH-major] Breast Neoplasms / secondary. Melanoma, Amelanotic / secondary. Neoplasms, Unknown Primary / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Adult. Antigens, Neoplasm / metabolism. Female. Humans. Melanoma-Specific Antigens. Neoplasm Proteins / metabolism. S100 Proteins / metabolism

  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18971788.001).
  • [ISSN] 1473-5636
  • [Journal-full-title] Melanoma research
  • [ISO-abbreviation] Melanoma Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  •  go-up   go-down


46. Lee SH, Hong JS, Choi JH, Chung WS: Choroidal schwannoma. Acta Ophthalmol Scand; 2005 Dec;83(6):754-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSIONS: We enucleated the eyeball with a clinical diagnosis of choroidal amelanotic melanoma, but the tumor was finally diagnosed as schwannoma.

  • Genetic Alliance. consumer health - Schwannoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16396657.001).
  • [ISSN] 1395-3907
  • [Journal-full-title] Acta ophthalmologica Scandinavica
  • [ISO-abbreviation] Acta Ophthalmol Scand
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  •  go-up   go-down


47. Conforti F, Menichini F, Rigano D, Senatore F: Antiproliferative activity on human cancer cell lines after treatment with polyphenolic compounds isolated from Iris pseudopumila flowers and rhizomes. Z Naturforsch C; 2009 Jul-Aug;64(7-8):490-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The in vitro cytotoxic activity assay against two human cancer cell lines, large lung carcinoma (CORL-23) and amelanotic melanoma (C32), showed that the most antiproliferative extract was the MeOH extract from flowers with a percentage of inhibition of 50.9 at 100 microg/ml against amelanotic melanoma cells.
  • The most antiproliferative compounds against amelanotic melanoma cells were kaempferol-3-O-beta-D-glucopyranoside and irisolidone with a percentage of inhibition of 100 and 96.6, respectively, and against large lung carcinoma cells with a percentage of inhibition of 82.1 and 84.6, respectively.
  • Significant activity on the amelanotic melanoma cell line was also showed by irigenin-7-O-beta-D-glucopyranoside, with a percentage of inhibition of 89.3.
  • The compounds isovitexin and isoorientin-6-O''-beta-D-glucopyranoside showed a selective activity against amelanotic melanoma cells with a percentage of inhibition of 83.2 and 79.8, respectively.
  • [MeSH-minor] Carcinoma, Large Cell / pathology. Cell Line, Tumor. Humans. Lung Neoplasms / pathology. Melanoma, Amelanotic / pathology. Plant Extracts / chemistry. Polyphenols

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19791498.001).
  • [ISSN] 0939-5075
  • [Journal-full-title] Zeitschrift für Naturforschung. C, Journal of biosciences
  • [ISO-abbreviation] Z. Naturforsch., C, J. Biosci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Flavonoids; 0 / Phenols; 0 / Plant Extracts; 0 / Polyphenols
  •  go-up   go-down


48. Donaldson MJ, Lim L, Harper CA, Mackenzie J, G Campbell W: Primary treatment of choroidal amelanotic melanoma with photodynamic therapy. Clin Exp Ophthalmol; 2005 Oct;33(5):548-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary treatment of choroidal amelanotic melanoma with photodynamic therapy.
  • The management of choroidal melanoma involves a delicate balance between preserving vision and preventing metastasis.
  • Transpupillary thermotherapy avoids these side-effects; however, it can also result in visual loss and its effectiveness is limited in amelanotic lesions.
  • Photodynamic therapy with verteporfin has shown promise in animal studies of choroidal melanoma, and has recently been used in the management of lesions that have failed to respond to conventional therapy.
  • The authors report a case of primary treatment of a small choroidal amelanotic melanoma with photodynamic therapy using verteporfin.
  • [MeSH-major] Choroid Neoplasms / drug therapy. Melanoma, Amelanotic / drug therapy. Photochemotherapy. Photosensitizing Agents / therapeutic use. Porphyrins / therapeutic use

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Clin Exp Ophthalmol. 2006 Sep-Oct;34(7):721; author reply 721-2 [16970777.001]
  • (PMID = 16181294.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Porphyrins; 129497-78-5 / verteporfin
  •  go-up   go-down


49. Harwood M, Telang GH, Robinson-Bostom L, Jellinek N: Melanoma and squamous cell carcinoma on different nails of the same hand. J Am Acad Dermatol; 2008 Feb;58(2):323-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Melanoma and squamous cell carcinoma on different nails of the same hand.
  • A case is presented of a patient with two separate and concurrent malignant neoplasms of the nail unit, on different nails on the same hand, each featuring an unusual clinical presentation: amelanotic melanoma presenting as longitudinal erythronychia and squamous cell carcinoma in situ presenting as longitudinal melanonychia.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Melanoma, Amelanotic / pathology. Nail Diseases / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Carcinoma, Squamous Cell.
  • MedlinePlus Health Information. consumer health - Nail Diseases.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18222331.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


50. Yoon TY, Kim HJ, Kim JW, Kim MK, Lee JY: Bowen's disease concealed by purpura. J Dermatol; 2007 Jan;34(1):65-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bowen's disease concealed by purpura.
  • Bowen's disease (BD) is a squamous cell carcinoma in situ characterized by a well-demarcated scaly erythematous thin plaque with an irregular outline.
  • Clinically, BD is frequently misdiagnosed as superficial basal cell carcinoma, patches of dermatitis, psoriasis, lichen planus, actinic keratosis, benign lichenoid keratosis, irritated seborrheic keratosis, viral warts, amelanotic melanoma or melanoma.
  • [MeSH-major] Bowen's Disease / complications. Purpura / complications. Scalp. Skin Neoplasms / complications

  • Genetic Alliance. consumer health - Bowen's Disease.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17204105.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


51. Ren G, Miao Z, Liu H, Jiang L, Limpa-Amara N, Mahmood A, Gambhir SS, Cheng Z: Melanin-targeted preclinical PET imaging of melanoma metastasis. J Nucl Med; 2009 Oct;50(10):1692-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Melanin-targeted preclinical PET imaging of melanoma metastasis.
  • Dialkylamino-alkyl-benzamides possess an affinity for melanin, suggesting that labeling of such benzamides with (18)F could potentially produce melanin-targeted PET probes able to identify melanotic melanoma metastases in vivo with high sensitivity and specificity.
  • In vivo distribution and small-animal PET studies were conducted on mice bearing B16F10 melanoma, A375M amelanotic melanoma, and U87MG tumors, and comparative studies were performed with (18)F-FDG PET in the melanoma models.
  • In vivo, (18)F-FBZA displayed significant tumor uptake; at 2 h, 5.94 +/- 1.83 percentage injected dose (%ID) per gram was observed in B16F10 tumors and only 0.75 +/- 0.09 %ID/g and 0.56 +/- 0.13 %ID/g was observed in amelanotic A375M and U87MG tumors, respectively.
  • CONCLUSION: (18)F-FBZA specifically targets primary and metastatic melanotic melanoma lesions with high tumor uptake and may have translational potential.

  • MedlinePlus Health Information. consumer health - Melanoma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Pigment Cell Res. 2000 Aug;13(4):283-93 [10952398.001]
  • [Cites] J Med Chem. 2000 Oct 19;43(21):3913-22 [11052796.001]
  • [Cites] J Nucl Med. 2001 Feb;42(2):248-56 [11216523.001]
  • [Cites] J Med Chem. 2001 Sep 13;44(19):3132-40 [11543682.001]
  • [Cites] Melanoma Res. 2002 Apr;12(2):115-21 [11930107.001]
  • [Cites] Br J Surg. 2002 Apr;89(4):389-96 [11952577.001]
  • [Cites] Nat Rev Cancer. 2002 Sep;2(9):683-93 [12209157.001]
  • [Cites] Eur J Nucl Med Mol Imaging. 2002 Nov;29(11):1478-84 [12397467.001]
  • [Cites] J Med Chem. 2002 Dec 19;45(26):5802-5 [12477363.001]
  • [Cites] Mol Imaging. 2003 Jul;2(3):131-7 [14649056.001]
  • [Cites] J Nucl Med. 2003 Dec;44(12):1927-32 [14660718.001]
  • [Cites] Cancer Res. 2004 Feb 15;64(4):1411-8 [14973076.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14865-70 [15469923.001]
  • [Cites] Cancer Res. 1984 Mar;44(3):1128-34 [6318981.001]
  • [Cites] Drug Metab Rev. 1984;15(5-6):1183-212 [6396056.001]
  • [Cites] Radiology. 1985 May;155(2):487-92 [3983400.001]
  • [Cites] Pigment Cell Res. 1989 Jan-Feb;2(1):34-9 [2717528.001]
  • [Cites] J Nucl Med. 1989 Mar;30(3):390-7 [2472474.001]
  • [Cites] J Nucl Med. 1991 Aug;32(8):1573-80 [1869982.001]
  • [Cites] Cancer. 1991 Dec 15;68(12):2579-81 [1933805.001]
  • [Cites] Biochem J. 1991 Dec 15;280 ( Pt 3):721-5 [1764036.001]
  • [Cites] J Invest Dermatol. 1993 Jun;100(6):806-11 [8496620.001]
  • [Cites] J Nucl Med. 1993 Aug;34(8):1260-6 [8326382.001]
  • [Cites] J Nucl Med. 1994 Nov;35(11):1741-7 [7965150.001]
  • [Cites] J Nucl Med. 1995 Oct;36(10):1806-10 [7562047.001]
  • [Cites] J Nucl Med. 1997 Jan;38(1):127-33 [8998166.001]
  • [Cites] Anticancer Res. 1997 May-Jun;17(3B):1577-82 [9179197.001]
  • [Cites] Lancet. 2005 Feb 19-25;365(9460):687-701 [15721476.001]
  • [Cites] Cancer Res. 2005 Jun 15;65(12):4979-86 [15958536.001]
  • [Cites] J Nucl Med. 2005 Aug;46(8):1333-41 [16085591.001]
  • [Cites] Cancer Biother Radiopharm. 2006 Apr;21(2):117-29 [16706632.001]
  • [Cites] J Nucl Med. 2006 Jun;47(6):957-67 [16741305.001]
  • [Cites] J Nucl Med. 2007 Jun;48(6):987-94 [17504880.001]
  • [Cites] Surg Oncol Clin N Am. 2007 Apr;16(2):403-30 [17560520.001]
  • [Cites] J Med Chem. 2007 Jul 26;50(15):3561-72 [17602544.001]
  • [Cites] CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96 [18287387.001]
  • [Cites] J Med Chem. 2008 Jun 12;51(11):3133-44 [18481842.001]
  • [Cites] Bioorg Med Chem. 2008 Aug 15;16(16):7671-90 [18656367.001]
  • [Cites] Clin Cancer Res. 2009 Apr 1;15(7):2373-9 [19293257.001]
  • (PMID = 19759116.001).
  • [ISSN] 1535-5667
  • [Journal-full-title] Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • [ISO-abbreviation] J. Nucl. Med.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA114747; United States / NCI NIH HHS / CA / R24 CA93862
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzamides; 0 / Fluorine Radioisotopes; 0 / Melanins; 0 / Receptors, sigma
  • [Other-IDs] NLM/ NIHMS636087; NLM/ PMC4215196
  •  go-up   go-down


52. Schacht V, Szeimies RM, Abels C: Photodynamic therapy with 5-aminolevulinic acid induces distinct microcirculatory effects following systemic or topical application. Photochem Photobiol Sci; 2006 May;5(5):452-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Amelanotic melanomas were implanted in the dorsal skin fold chamber of Syrian Golden hamsters.
  • [MeSH-major] Aminolevulinic Acid / administration & dosage. Melanoma / drug therapy. Photochemotherapy. Photosensitizing Agents / administration & dosage. Skin / blood supply. Skin Neoplasms / drug therapy

  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16685321.001).
  • [ISSN] 1474-905X
  • [Journal-full-title] Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
  • [ISO-abbreviation] Photochem. Photobiol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 88755TAZ87 / Aminolevulinic Acid
  •  go-up   go-down


53. Godbole D, Mojamdar M, Pal JK: Increased level of p27 subunit of proteasomes and its co-localization with tyrosinase in amelanotic melanoma cells indicate its direct role in the regulation of melanin biosynthesis. Cell Biol Int; 2006 Nov;30(11):895-902
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Increased level of p27 subunit of proteasomes and its co-localization with tyrosinase in amelanotic melanoma cells indicate its direct role in the regulation of melanin biosynthesis.
  • Proteasomes have been shown to be involved in the regulation of melanin biosynthesis in melanoma cells.
  • Here we report on the correlation between proteasome subunits and Tyrosinase (Tyr) activity in different cell phenotypes, and thereby regulation of melanin biosynthesis in B16F10 mouse melanoma cells.
  • Our results indicated that the quantity of proteasome subunit p27 is higher and that of the enzyme Tyr and its activity are lower in amelanotic melanoma cells, while the reverse is true in melanotic melanoma cells.
  • Proteasome subunit p27, compared to another subunit p31, shows increased co-localization with Tyr and Tyrosinase related protein 1 (Trp1) in amelanotic cells to a greater extent than that in melanotic cells.
  • On exposure to cycloheximide, increased Tyr degradation was seen in amelanotic cells, as indicated by increased co-localization of p27 and Tyr.
  • Further, exposure of amelanotic melanoma cells with proteasome-specific inhibitor MG132 resulted in an increased Tyr activity, increased levels of Tyr and Trp1, leading to increased melanin synthesis.
  • These results therefore suggest that proteasomes, particularly p27 subunit, are directly involved in the regulation of melanin biosynthesis in mouse melanoma cells.
  • [MeSH-major] Melanins / biosynthesis. Melanoma, Amelanotic / enzymology. Melanoma, Amelanotic / pathology. Monophenol Monooxygenase / metabolism. Proteasome Endopeptidase Complex / metabolism. Protein Subunits / metabolism

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CYCLOHEXIMIDE .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16879986.001).
  • [ISSN] 1065-6995
  • [Journal-full-title] Cell biology international
  • [ISO-abbreviation] Cell Biol. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Leupeptins; 0 / Melanins; 0 / Proteasome Inhibitors; 0 / Protein Subunits; 133407-82-6 / benzyloxycarbonylleucyl-leucyl-leucine aldehyde; 98600C0908 / Cycloheximide; EC 1.- / Oxidoreductases; EC 1.14.18.- / tyrosinase-related protein-1; EC 1.14.18.1 / Monophenol Monooxygenase; EC 3.4.25.1 / Proteasome Endopeptidase Complex
  •  go-up   go-down


54. Valdes A, Kulekowskis AM, Curtis L: Case report: amelanotic melanoma located on the lower extremity. Am Fam Physician; 2007 Dec 1;76(11):1614, 1618
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case report: amelanotic melanoma located on the lower extremity.
  • [MeSH-major] Foot. Melanoma, Amelanotic. Skin Neoplasms

  • MedlinePlus Health Information. consumer health - Foot Health.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Am Fam Physician. 2005 Jul 15;72(2):269-76 [16050450.001]
  • (PMID = 18092703.001).
  • [ISSN] 0002-838X
  • [Journal-full-title] American family physician
  • [ISO-abbreviation] Am Fam Physician
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] United States
  •  go-up   go-down


55. Kurotaki T, Tomonari Y, Kanno T, Wako Y, Tsuchitani M: A novel immunohistochemical marker of normal and neoplastic melanocytes in formalin-fixed, paraffin-embedded tissues of albino rats. Vet Pathol; 2008 May;45(3):383-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The samples consisted of 11 (1.57%) amelanotic melanomas in 700 rats (2 studies), 23 non-melanocytic tumors, and a wide variety of normal tissues.
  • In amelanotic melanoma, the tumor cells consisted of spindle cells with eosinophilic cytoplasm without melanin granules.
  • PNL2 consistently stained cytoplasm in all amelanotic melanoma cells.
  • [MeSH-major] Melanocytes / cytology. Melanocytes / pathology. Melanoma / pathology

  • MedlinePlus Health Information. consumer health - Melanoma.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18487499.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


56. Traynor NJ, McKenzie RC, Beckett GJ, Gibbs NK: Selenomethionine inhibits ultraviolet radiation-induced p53 transactivation. Photodermatol Photoimmunol Photomed; 2006 Dec;22(6):297-303
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: We examined whether selenomethionine could protect human skin cells from UV radiation-induced p53 transactivation, using a pRGCDeltafos-lacZ p53-dependent reporter construct stably transfected in an amelanotic melanoma cell line (Arn-8) which expresses wild-type p53.

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. SELENIUM METHIONINE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17100737.001).
  • [ISSN] 0905-4383
  • [Journal-full-title] Photodermatology, photoimmunology & photomedicine
  • [ISO-abbreviation] Photodermatol Photoimmunol Photomed
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Radiation-Protective Agents; 0 / Tumor Suppressor Protein p53; 964MRK2PEL / Selenomethionine
  •  go-up   go-down


57. Wachulska M, Kozłowska K, Cichorek M: The DNA ploidy and proliferative activity of transplantable melanoma cells in regard to their secretory function. Neoplasma; 2005;52(4):280-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The DNA ploidy and proliferative activity of transplantable melanoma cells in regard to their secretory function.
  • The study concerns DNA ploidy and proliferative activity of the cells of two hamster transplantable melanoma lines - differing in many biological features - in the light of possible changes in their secretory activity.
  • Our results indicate that melanotic melanoma cells (Ma) have a near-tetraploid DNAcontent and about 18% of proliferating cells, while amelanotic melanoma cells (Ab) - have a near-triploid DNA content and almost twice as many proliferating cells.
  • The Ab cells, in comparison with Ma cells, secreted in vitro less total protein and most of the cytokines examined except OSM, but a spontaneous alteration of transplantable melanoma was accompanied by an increase of the quantity and dynamics of NO secretion.
  • So, the cells of two melanoma lines have their own characteristic pattern of secretory function.
  • But, the aneuploidy which accompanied the changes in cell differentiation of the studied melanoma lines, although seemed to reflect their changes in the proliferative activity, nevertheless did not reflect, in a direct way, differences in the secretion of the substances studied.
  • [MeSH-major] DNA, Neoplasm / analysis. Melanoma / pathology. Melanoma / secretion. Ploidies. Skin Neoplasms / pathology. Skin Neoplasms / secretion


58. Panasiti V, Devirgiliis V, Curzio M, Roberti V, Gobbi S, Masciangelo R, Mastrecchia B, Calvieri S, Bottoni U: The reticular point of view in dermatoscopy. J Am Acad Dermatol; 2009 Oct;61(4):605-10
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We sought to develop and evaluate a diagnostic scoring system, the reticular point of view, to distinguish common melanocytic nevus from dysplastic nevus and from melanoma.
  • RESULTS: Among the lesions excised, histopathologic examination revealed 33 (10.28%) melanomas.
  • Regarding the diagnosis of melanoma, only the presence of large holes, areas of abrupt cut off, and linear extensions revealed statistical significance.
  • It is not applicable in nodular, thick, and amelanotic melanomas that are usually lacking in pigment network.
  • CONCLUSION: Although pattern analysis represents the most effective analytical method in dermatoscopy, our scoring system may be useful to distinguish between benign lesions, which need only clinical follow-up, and malignant lesions, which need surgical excision.
  • [MeSH-major] Algorithms. Dermoscopy / methods. Dysplastic Nevus Syndrome / diagnosis. Melanoma / diagnosis. Nevus, Pigmented / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19703721.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


59. Patel GA, Ragi G, Krysicki J, Schwartz RA: Subungual melanoma: a deceptive disorder. Acta Dermatovenerol Croat; 2008;16(4):236-42
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subungual melanoma: a deceptive disorder.
  • Subungual melanoma is an uncommon form of acral melanoma that arises within the nail bed.
  • The incidence for acral melanomas is similar worldwide, but the proportion is higher in dark-skinned individuals.
  • The subungual form represents about 2% of cutaneous non-sun induced melanomas in the western world, and up to 75% in Africans, 10% in Japanese, and 25% in the Chinese of Hong Kong.
  • Up to 33% of subungual melanomas are amelanotic.
  • Non-specific features and symptoms along with a high incidence of amelanosis often lead to delayed diagnosis, disease progression, and a poor prognosis with challenging treatment options.
  • [MeSH-major] Melanoma / diagnosis. Nail Diseases / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Nail Diseases.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19111151.001).
  • [ISSN] 1330-027X
  • [Journal-full-title] Acta dermatovenerologica Croatica : ADC
  • [ISO-abbreviation] Acta Dermatovenerol Croat
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Croatia
  • [Number-of-references] 40
  •  go-up   go-down


60. Elizalde J, Ubia S, Barraquer RI: Adenoma of the nonpigmented ciliary epithelium. Eur J Ophthalmol; 2006 Jul-Aug;16(4):630-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenoma of the non pigmented ciliary epithelium may mimic an amelanotic melanoma.

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16952109.001).
  • [ISSN] 1120-6721
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


61. McGregor DH, Cherian R, Romanas MM, Ulusarac O, Mathur SC, Feldman MM: Amelanotic malignant melanoma: two collision tumors presenting as basal cell carcinoma and atypical fibroxanthoma. Ann Clin Lab Sci; 2008;38(2):157-62
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma: two collision tumors presenting as basal cell carcinoma and atypical fibroxanthoma.
  • We report 2 cases of collision tumors involving amelanotic malignant melanoma of the back.
  • Subsequent excision showed that the lesion was largely composed of amelanotic melanoma underlying a relatively small and thin basal cell carcinoma, and this probably would have been demonstrated in a punch (rather than shave) biopsy.
  • The other patient is a 71-yr-old male with a 1 cm exophytic lesion on the back, which was determined microscopically to be melanoma, and a 0.6 cm papule on the back.
  • This lesion was composed of 2 distinct contiguous neoplastic infiltrates, the predominant component being an atypical fibroxanthoma and the smaller component an amelanotic melanoma (primary vs metastatic), with diagnostic confirmation requiring multiple immunohistochemical stains.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Melanoma, Amelanotic / diagnosis. Neoplasms, Multiple Primary / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18469362.001).
  • [ISSN] 1550-8080
  • [Journal-full-title] Annals of clinical and laboratory science
  • [ISO-abbreviation] Ann. Clin. Lab. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor
  •  go-up   go-down


62. Gosselink CP, Sindone JL, Meadows BJ, Mohammadi A, Rosa M: Amelanotic subungual melanoma: a case report. J Foot Ankle Surg; 2009 Mar-Apr;48(2):220-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic subungual melanoma: a case report.
  • Subungual melanoma is a disorder that accounts for 2% to 3% of all melanoma cases.
  • We report the case of a 31-year-old male patient presenting with a rapidly growing mass localized to the hallux, which eventually resulted in the diagnosis of an ulcerated amelanotic subungual melanoma.
  • Because of their lack of pigmentation, amelanotic melanoma is frequently misdiagnosed for other more common forms of cutaneous compromise, and a delay in proper treatment because of failure to make the diagnosis can greatly decrease the likelihood of a favorable outcome.
  • [MeSH-major] Hallux. Melanoma, Amelanotic / pathology. Nail Diseases / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Nail Diseases.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19232976.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


63. Heidemann J, Lebiedz P, Herbst H, Spahn TW, Domagk D, Domschke W, Kucharzik T: Amelanotic malignant melanoma of the esophagus: case report. Z Gastroenterol; 2005 Jun;43(6):597-600
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the esophagus: case report.
  • We present the case of a primary malignant esophageal melanoma arising in a 75-year-old male, initially diagnosed as anaplastic squamous cell carcinoma.
  • After resection of the tumor, histological work-up was indicative of a marked morphological heterogeneity, resembling a focally amelanotic primary malignant melanoma.
  • Primary malignant melanomas of the esophagus are exceptionally rare.
  • [MeSH-major] Carcinoma, Squamous Cell / radiography. Esophageal Neoplasms / pathology. Esophageal Neoplasms / radiography. Melanoma / pathology. Melanoma / radiography

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15986290.001).
  • [ISSN] 0044-2771
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


64. Matusiak L, Bieniek A, Wozniak Z, Szepietowski JC: Amelanotic malignant melanoma in an acral location. Acta Dermatovenerol Alp Pannonica Adriat; 2008 Jun;17(2):72-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma in an acral location.
  • The biopsy, stained with H and E, revealed an anaplastic malignant tumor.
  • Additional immunochemical staining with Melan A allowed us to make the final diagnosis: amelanotic malignant melanoma (MM).
  • The melanoma was removed by amputation of digits IV and V, with partial removal of the metatarsal bones (Clark degree 5, Breslow thickness 9 mm).
  • [MeSH-major] Foot Dermatoses / pathology. Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18709293.001).
  • [ISSN] 1318-4458
  • [Journal-full-title] Acta dermatovenerologica Alpina, Pannonica, et Adriatica
  • [ISO-abbreviation] Acta Dermatovenerol Alp Pannonica Adriat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Slovenia
  •  go-up   go-down


65. Auer-Grumbach M: Hereditary sensory neuropathy type I. Orphanet J Rare Dis; 2008;3:7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hereditary sensory neuropathy type I (HSN I) is a slowly progressive neurological disorder characterised by prominent predominantly distal sensory loss, autonomic disturbances, autosomal dominant inheritance, and juvenile or adulthood disease onset.
  • Disease onset varies between the 2nd and 5th decade of life.
  • Differential diagnosis includes the other hereditary sensory and autonomic neuropathies (HSAN), especially HSAN II, as well as diabetic foot syndrome, alcoholic neuropathy, neuropathies caused by other neurotoxins/drugs, immune mediated neuropathy, amyloidosis, spinal cord diseases, tabes dorsalis, lepra neuropathy, or decaying skin tumours like amelanotic melanoma.
  • The disorder is slowly progressive and does not influence life expectancy but is often severely disabling after a long duration of the disease.

  • The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for hereditary sensory neuropathy .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nat Cell Biol. 1999 Oct;1(6):376-82 [10559966.001]
  • [Cites] Curr Opin Neurol. 2006 Oct;19(5):474-80 [16969157.001]
  • [Cites] Neurology. 2000 Nov 28;55(10):1552-7 [11094113.001]
  • [Cites] Muscle Nerve. 2000 Oct;23(10):1508-14 [11003785.001]
  • [Cites] Nat Genet. 2001 Mar;27(3):261-2 [11242106.001]
  • [Cites] Nat Genet. 2001 Mar;27(3):309-12 [11242114.001]
  • [Cites] Am J Hum Genet. 2001 Sep;69(3):655-9 [11479835.001]
  • [Cites] Neuromuscul Disord. 2002 Mar;12(3):286-91 [11801401.001]
  • [Cites] J Biol Chem. 2002 Mar 22;277(12):10194-200 [11781309.001]
  • [Cites] Neuromuscul Disord. 2002 Oct;12(7-8):656-8 [12207934.001]
  • [Cites] J Clin Invest. 2002 Nov;110(9):1301-8 [12417569.001]
  • [Cites] Am J Hum Genet. 2003 Mar;72(3):722-7 [12545426.001]
  • [Cites] Arch Neurol. 2003 Mar;60(3):329-34 [12633143.001]
  • [Cites] Biochim Biophys Acta. 2003 Jun 10;1632(1-3):16-30 [12782147.001]
  • [Cites] Am J Hum Genet. 2003 Sep;73(3):632-7 [12870133.001]
  • [Cites] Biochim Biophys Acta. 2004 Mar 2;1688(2):168-75 [14990347.001]
  • [Cites] Neurology. 2004 Mar 23;62(6):1001-2 [15037712.001]
  • [Cites] Curr Opin Neurol. 2004 Oct;17(5):569-77 [15367861.001]
  • [Cites] Ann Neurol. 2004 Oct;56(4):586-90 [15455439.001]
  • [Cites] Arch Neurol. 1974 May;30(5):359-71 [4132408.001]
  • [Cites] Am J Hum Genet. 1995 Oct;57(4):853-8 [7573046.001]
  • [Cites] Nat Genet. 1996 May;13(1):101-4 [8673084.001]
  • [Cites] Am J Hum Genet. 1996 Jul;59(1):258-62 [8659534.001]
  • [Cites] Neurology. 1997 Jan;48(1):23-8 [9008488.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1997 Jun;62(6):570-3 [9219740.001]
  • [Cites] Science. 1998 Jan 23;279(5350):580-5 [9438855.001]
  • [Cites] J Neurol Sci. 2004 Dec 15;227(1):35-8 [15546589.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2005 Jul;76(7):1022-4 [15965219.001]
  • [Cites] Brain. 2005 Dec;128(Pt 12):2797-810 [16311270.001]
  • [Cites] Brain. 2006 Feb;129(Pt 2):411-25 [16364956.001]
  • [Cites] Neurology. 2000 Jan 11;54(1):45-52 [10636124.001]
  • (PMID = 18348718.001).
  • [ISSN] 1750-1172
  • [Journal-full-title] Orphanet journal of rare diseases
  • [ISO-abbreviation] Orphanet J Rare Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 35
  • [Other-IDs] NLM/ PMC2311280
  •  go-up   go-down


66. Schöttler L, Körber A, Denisjuk N, Freise J, Dissemond J: [Malignant melanoma masquerading as a neurotrophic ulcer]. Med Klin (Munich); 2009 Sep 15;104(9):723-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant melanoma masquerading as a neurotrophic ulcer].
  • [Transliterated title] Malignes Melanom imitiert ein neurotrophes Ulkus.
  • After the initial examination in the outpatient wound healing clinic, a malignant melanoma already showing invasive growth with a penetration depth of 4.6 mm was detected in a biopsy.
  • CONCLUSION: Malignant melanoma is a primary cutaneous malignant tumor.
  • Ulcerated and amelanotic melanomas still present a considerable clinical challenge due to the likelihood of being mistaken for benign diseases and the occurrence of filiae when diagnosis is made too late.
  • This case report demonstrates the importance of differential diagnostic consideration of neoplasias, for example malignant melanoma, in cases of unclear, therapy-refractory wounds and discusses the relevant aspects in avoiding an unnecessary prolongation of diagnostics.
  • [MeSH-major] Diabetic Foot / diagnosis. Diabetic Nephropathies / diagnosis. Heel. Melanoma / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Diabetic Foot.
  • MedlinePlus Health Information. consumer health - Diabetic Kidney Problems.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br J Dermatol. 2002 Apr;146 Suppl 61:24-30 [11966729.001]
  • [Cites] Dermatology. 2003;206(2):76-7 [12592070.001]
  • [Cites] Clin Exp Med. 2004 Oct;4(2):65-77 [15672943.001]
  • [Cites] Hautarzt. 2004 Feb;55(2):195-213 [15043023.001]
  • [Cites] Skin Pharmacol Appl Skin Physiol. 2001 Sep-Oct;14(5):280-90 [11586069.001]
  • [Cites] Oncogene. 2003 May 19;22(20):3042-52 [12789279.001]
  • [Cites] Br J Dermatol. 2002 Apr;146 Suppl 61:11-6 [11966726.001]
  • [Cites] Cancer. 2005 Feb 1;103(3):616-24 [15630700.001]
  • (PMID = 19779677.001).
  • [ISSN] 1615-6722
  • [Journal-full-title] Medizinische Klinik (Munich, Germany : 1983)
  • [ISO-abbreviation] Med. Klin. (Munich)
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 9008-11-1 / Interferons
  •  go-up   go-down


67. Lovato L, Salerni G, Puig S, Carrera C, Palou J, Malvehy J: Adult xanthogranuloma mimicking basal cell carcinoma: dermoscopy, reflectance confocal microscopy and pathological correlation. Dermatology; 2010;220(1):66-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Juvenile xanthogranuloma in adulthood is an infrequent non-Langerhans cell histiocytosis, which may simulate malignant tumors such as basal cell carcinoma (BCC) or amelanotic melanoma.

  • Genetic Alliance. consumer health - Xanthogranuloma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • [CommentIn] J Cutan Pathol. 2017 Sep;44(9):809-810 [28671710.001]
  • (PMID = 19996569.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  •  go-up   go-down


68. Stroh C, Manger T: [Primary amelanotic anorectal melanoma--a case report]. Zentralbl Chir; 2007 Dec;132(6):560-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary amelanotic anorectal melanoma--a case report].
  • [Transliterated title] Das primäre amelanotische Melanom des Rektums - Ein Fallbericht.
  • BACKGROUND: The amelanotic melanoma of the rectal mucosa is very rare with an unfavourable prognosis.
  • METHODS: In literature 5 cases of amelanotic malignant melanoma were reported.
  • RESULTS: We report about a 55-year-old female patient with an amelanotic melanoma of rectal mucosa.
  • CONCLUSION: The prognosis of primary malignant anorectal melanoma is poor, irrespective of surgical treatment.
  • Wide local resection is the first choice for primary anorectal melanoma.
  • Chemotherapy, radiotherapy and immunotherapy should be considered in the treatment of anorectal melanoma to influence the overall survival.
  • [MeSH-major] Melanoma, Amelanotic / surgery. Rectal Neoplasms / surgery
  • [MeSH-minor] Chemotherapy, Adjuvant. Disease Progression. Endosonography. Fatal Outcome. Female. Follow-Up Studies. Humans. Intestinal Mucosa / pathology. Intestinal Mucosa / surgery. Intestinal Mucosa / ultrasonography. Lymph Node Excision. Middle Aged. Neoplasm Recurrence, Local / drug therapy. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Recurrence, Local / ultrasonography. Neoplasm Staging. Palliative Care. Proctoscopy. Radiotherapy, Adjuvant. Reoperation

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18098086.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


69. Sbano P, Nami N, Grimaldi L, Rubegni P: True amelanotic melanoma: the great masquerader. J Plast Reconstr Aesthet Surg; 2010 Mar;63(3):e307-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] True amelanotic melanoma: the great masquerader.
  • [MeSH-major] Dermoscopy. Melanoma / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19713163.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
  •  go-up   go-down


70. Jacob S, Pye E, Hbahbih M, Messios N, Rajabally YA: Rapidly progressive bilateral ophthalmoplegia and enlarging sellar mass caused by amelanotic melanoma. J Neuroophthalmol; 2006 Mar;26(1):49-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rapidly progressive bilateral ophthalmoplegia and enlarging sellar mass caused by amelanotic melanoma.
  • Hypophysectomy disclosed an amelanotic melanoma.
  • There are seven reported cases of melanoma arising primarily in the sella turcica.
  • Two cases of metastatic melanoma to the cavernous sinuses have been reported.
  • Amelanotic melanoma has not been reported as a cause of cavernous sinus syndrome.
  • [MeSH-major] Melanoma, Amelanotic / complications. Ophthalmoplegia / etiology. Pituitary Neoplasms / complications. Sella Turcica / pathology
  • [MeSH-minor] Diagnosis, Differential. Disease Progression. Female. Follow-Up Studies. Humans. Hypophysectomy. Magnetic Resonance Imaging. Middle Aged

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16518168.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


71. Said A, Tundis R, Hawas UW, El-Kousy SM, Rashed K, Menichini F, Bonesi M, Huefner A, Loizzo MR, Menichinib F: In vitro antioxidant and antiproliferative activities of flavonoids from Ailanthus excelsa (Roxb.) (Simaroubaceae) leaves. Z Naturforsch C; 2010 Mar-Apr;65(3-4):180-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Compounds 1 and 3 inhibited cell growth in both amelanotic melanoma and malignant melanoma cells.

  • MedlinePlus Health Information. consumer health - Antioxidants.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20469635.001).
  • [ISSN] 0939-5075
  • [Journal-full-title] Zeitschrift für Naturforschung. C, Journal of biosciences
  • [ISO-abbreviation] Z. Naturforsch., C, J. Biosci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Biphenyl Compounds; 0 / Flavonoids; 0 / Free Radical Scavengers; 0 / Picrates; 1898-66-4 / 2,2-diphenyl-1-picrylhydrazyl
  •  go-up   go-down


72. Gualandri L, Betti R, Crosti C: Clinical features of 36 cases of amelanotic melanomas and considerations about the relationship between histologic subtypes and diagnostic delay. J Eur Acad Dermatol Venereol; 2009 Mar;23(3):283-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical features of 36 cases of amelanotic melanomas and considerations about the relationship between histologic subtypes and diagnostic delay.
  • BACKGROUND: Amelanotic melanomas (AM) are a difficult diagnostic challenge for clinicians.
  • OBJECTIVE: To consider the clinical presentation of AM, the histologic subtypes involved, the relationship with the diagnostic delay and the possible involvement in overall prognosis.
  • PATIENTS/METHODS: Patients who were observed in our department to be affected by cutaneous melanomas were recorded.
  • AM were divided in three main clinical types: an erythematous macule or patch on sun-exposed skin, a dermal plaque or nodule without a particular epidermal change, an exophytic nodule.
  • Only pure AM were considered.
  • Histological subtypes considered were superficial spreading melanoma, nodular melanoma, and lentigo maligna melanoma.
  • Diagnostic delay considered from when the patients first noticed the lesion on the site where the melanoma was diagnosed and when the physician or the patient first proposed the removal was recorded.
  • RESULTS: Thirty-six cases of AM out of a total of 500 melanomas (7.2%) were collected.
  • Mean Breslow thickness of AM was 1.72 mm compared to 0.61 mm of pigmented cases.
  • Nodular histotype was highly represented in AM (30.5% of cases) with respect to pigmented nodular melanomas (2.9%).
  • The diagnostic delay did not differ between amelanotic and pigmented melanomas, nor between nodular AM and nodular pigmented melanomas.
  • CONCLUSION: The great prevalence of clinical and histological nodular cases, the higher mean Breslow thickness (considered as the most important factor of prognosis) of AM compared with a not significant greater diagnostic delay may point out that a good percentage of AM have an intrinsic faster speed of growth with a worse prognosis irrespectively of the diagnostic performance.
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19207640.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


73. Camerin M, Rello S, Villanueva A, Ping X, Kenney ME, Rodgers MA, Jori G: Photothermal sensitisation as a novel therapeutic approach for tumours: studies at the cellular and animal level. Eur J Cancer; 2005 May;41(8):1203-12
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Irradiation of B78H1 murine amelanotic melanoma cells with 850 nm light emitted from a Ti:sapphire laser, operated in a pulsed mode at high fluence rates and in the presence of Ni(II)-octabutoxy-naphthalocyanine (NiNc), promoted a photothermally sensitised process leading to fast and irreversible cell death.
  • Very similar results were obtained upon irradiation of NiNc-loaded C32 human amelanotic melanoma cells and transformed murine HT-1080 and HaCaT fibroblasts.
  • From these results, photothermal sensitisation appears to be a general phenomenon and preliminary studies with mice bearing subcutaneously transplanted amelanotic melanomas, irradiated with 850 nm light 24 h after intravenous injection of NiNc, suggest that this approach has potential for the therapy of some types of skin tumours.
  • [MeSH-major] Melanoma, Amelanotic / drug therapy. Metalloporphyrins / therapeutic use. Photochemotherapy / methods. Photosensitizing Agents / therapeutic use

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15911245.001).
  • [ISSN] 0959-8049
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 91027
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Metalloporphyrins; 0 / Photosensitizing Agents; 0 / octabutoxynaphthalocyaninenickel(II)
  •  go-up   go-down


74. Harasymowycz P, Boucher MC, Corriveau C, Gauthier D, Allaire G: Choroidal amelanotic melanoma in a patient with oculocutaneous albinism. Can J Ophthalmol; 2005 Dec;40(6):754-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Choroidal amelanotic melanoma in a patient with oculocutaneous albinism.
  • CASE REPORT: We describe the clinical presentation of a choroidal amelanotic melanoma in a 46-year-old woman with oculocutaneous albinism.
  • Microscopic findings and histopathological features, demonstrating a spindle B-cell melanoma of the choroid, are also reviewed.
  • COMMENTS: Magnetic resonance imaging may be helpful in diagnosing amelanotic melanoma in patients with oculocutaneous albinism.

  • Genetic Alliance. consumer health - Albinism.
  • Genetic Alliance. consumer health - Oculocutaneous Albinism.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16391642.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


75. Harrison TM, Dominguez P, Hanzlik K, Sikarskie JG, Agnew D, Bergin I, Fitzgerald SD, Kitchell BE, McNiel E: Treatment of an amelanotic melanoma using radiation therapy in a lesser Madagascar hedgehog tenrec (Echinops telfairi). J Zoo Wildl Med; 2010 Mar;41(1):152-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of an amelanotic melanoma using radiation therapy in a lesser Madagascar hedgehog tenrec (Echinops telfairi).
  • Immunohistochemically, the original, recurrent, and metastatic populations were strongly positive for HMB 45 and weakly positive for S-100, and the final diagnosis was metastatic amelanotic melanoma.
  • [MeSH-major] Insectivora. Melanoma, Amelanotic / veterinary

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20722271.001).
  • [ISSN] 1042-7260
  • [Journal-full-title] Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians
  • [ISO-abbreviation] J. Zoo Wildl. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


76. Cavicchini S, Tourlaki A, Bottini S: Dermoscopic vascular patterns in nodular "pure" amelanotic melanoma. Arch Dermatol; 2007 Apr;143(4):556
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermoscopic vascular patterns in nodular "pure" amelanotic melanoma.
  • [MeSH-major] Dermoscopy. Melanoma, Amelanotic / blood supply. Skin Neoplasms / blood supply

  • Genetic Alliance. consumer health - Nodular melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17438200.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


77. Pouckova P, Skvor J, Gotte G, Vottariello F, Slavik JT, Matousek J, Laurents DV, Libonati M, Soucek J: Some biological actions of PEG-conjugated RNase A oligomers. Neoplasma; 2006;53(1):79-85
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this work we show that the chemical conjugation of PEG to the RNase A C-dimer, and to the two RNase A trimers (NC-trimer and C- trimer) decreases the aspermatogenic activity of the oligomers while increasing their inhibitory activity on the growth of the human UB900518 amelanotic melanoma transplanted in athymic nude mice.
  • [MeSH-minor] Animals. Antispermatogenic Agents / pharmacology. Cell Line, Tumor. Dimerization. Embryo, Mammalian / drug effects. Humans. Male. Melanoma, Experimental / drug therapy. Mice. Neoplasm Transplantation. Spermatogenesis / drug effects

  • COS Scholar Universe. author profiles.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16416018.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Antispermatogenic Agents; 0 / Peptide Fragments; 30IQX730WE / Polyethylene Glycols; EC 3.1.27.5 / Ribonuclease, Pancreatic
  •  go-up   go-down


78. Koszałka P, Szmit E, Myśliwski A, Bigda J: Anti-tumor action of tumor necrosis factor against Bomirski Ab melanoma in hamsters. Arch Immunol Ther Exp (Warsz); 2007 Jul-Aug;55(4):267-79
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anti-tumor action of tumor necrosis factor against Bomirski Ab melanoma in hamsters.
  • MATERIALS AND METHODS: The effects of intratumoral injection of rat TNF into hamsters bearing Bomirski Ab amelanotic melanoma, a fast growing tumor of high metastatic potential, were tested.
  • In vitro assays indicated a direct cytotoxic effect of TNF against Ab melanoma cells, most probably as an outcome of apoptosis.
  • Intratumoral application of TNF also caused some modulation of cytokine response in melanoma-bearing hamsters as evidenced by increased levels of IL-6 in blood serum.
  • CONCLUSIONS: This study established Bomirski Ab melanoma as a useful model for complex analysis of the anti-tumor activity of TNF.
  • [MeSH-major] Angiogenesis Inhibitors / metabolism. Melanoma, Experimental / metabolism. Neovascularization, Pathologic / metabolism. Recombinant Proteins / metabolism. Tumor Necrosis Factor-alpha / metabolism

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Neoplasma. 1995;42(1):15-9 [7617068.001]
  • [Cites] Int J Cancer. 1996 May 3;66(3):388-92 [8621262.001]
  • [Cites] Eur Cytokine Netw. 1996 Apr-Jun;7(2):93-124 [8688493.001]
  • [Cites] Cancer Immunol Immunother. 1996 May;42(4):231-6 [8665570.001]
  • [Cites] Immunol Cell Biol. 1996 Apr;74(2):151-8 [8724002.001]
  • [Cites] Br J Cancer. 1996 Dec;74(12):1908-15 [8980389.001]
  • [Cites] Biochem Biophys Res Commun. 1987 Mar 30;143(3):997-1004 [2436621.001]
  • [Cites] J Biol Chem. 1987 May 25;262(15):6951-4 [3034874.001]
  • [Cites] J Immunol. 1987 Jun 15;138(12):4185-91 [3108384.001]
  • [Cites] Virchows Arch B Cell Pathol Incl Mol Pathol. 1987;52(6):489-500 [2884771.001]
  • [Cites] Virchows Arch B Cell Pathol Incl Mol Pathol. 1987;53(6):353-8 [2891219.001]
  • [Cites] J Exp Med. 1988 Mar 1;167(3):1067-85 [3351434.001]
  • [Cites] J Exp Med. 1988 Mar 1;167(3):1086-99 [3258350.001]
  • [Cites] J Immunol. 1988 Jun 1;140(11):4056-61 [3372997.001]
  • [Cites] Cancer Metastasis Rev. 1988 Jun;7(2):95-118 [3293837.001]
  • [Cites] J Exp Med. 1988 Aug 1;168(2):637-47 [3411290.001]
  • [Cites] Cancer Res. 1988 Oct 1;48(19):5417-21 [3262009.001]
  • [Cites] Cancer Immunol Immunother. 1988;27(2):128-32 [2458181.001]
  • [Cites] Int J Cancer. 1988 Sep 15;42(3):395-9 [3417368.001]
  • [Cites] J Immunol. 1988 Oct 15;141(8):2629-34 [3171180.001]
  • [Cites] Cancer Lett. 1989 Jan;44(1):67-72 [2917343.001]
  • [Cites] Anticancer Res. 1997 May-Jun;17(3C):2207-11 [9216689.001]
  • [Cites] Anticancer Res. 1998 Jan-Feb;18(1A):441-3 [9568116.001]
  • [Cites] Infect Immun. 1998 May;66(5):2135-42 [9573100.001]
  • [Cites] Neoplasma. 1998;45(3):162-8 [9717529.001]
  • [Cites] Oncogene. 1999 Feb 25;18(8):1553-9 [10102625.001]
  • [Cites] Ann Surg. 2004 Dec;240(6):939-47; discussion 947-8 [15570199.001]
  • [Cites] Jpn J Cancer Res. 1989 Dec;80(12):1161-4 [2516844.001]
  • [Cites] J Immunol. 1990 Nov 1;145(9):2902-7 [2120340.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6427-32 [10841547.001]
  • [Cites] J Interferon Cytokine Res. 2001 Jul;21(7):475-84 [11506741.001]
  • [Cites] Cell Signal. 2002 Jun;14(6):477-92 [11897488.001]
  • [Cites] Neoplasma. 2002;49(5):319-22 [12458330.001]
  • [Cites] Clin Cancer Res. 2003 Jan;9(1):355-62 [12538488.001]
  • [Cites] J Immunol. 2003 Feb 15;170(4):2004-13 [12574370.001]
  • [Cites] J Cell Biochem. 2003 Jun 1;89(3):484-99 [12761882.001]
  • [Cites] Proc Natl Acad Sci U S A. 1975 Sep;72(9):3666-70 [1103152.001]
  • [Cites] Recent Results Cancer Res. 1980;75:207-12 [7232833.001]
  • [Cites] J Immunol Methods. 1983 Dec 16;65(1-2):55-63 [6606682.001]
  • [Cites] J Immunol. 1984 May;132(5):2464-9 [6609199.001]
  • [Cites] Int J Cancer. 1984 Aug 15;34(2):263-7 [6469400.001]
  • [Cites] Cell Immunol. 1985 Jul;93(2):265-79 [3159480.001]
  • [Cites] Science. 1985 Nov 8;230(4726):630-2 [2413547.001]
  • [Cites] Science. 1985 Nov 22;230(4728):943-5 [3933111.001]
  • [Cites] Biochem Biophys Res Commun. 1986 Apr 14;136(1):94-101 [3486658.001]
  • [Cites] Proc Natl Acad Sci U S A. 1986 Jun;83(11):3949-53 [3520561.001]
  • [Cites] Biochem Biophys Res Commun. 1986 Jun 30;137(3):1094-100 [3015137.001]
  • [Cites] J Immunol. 1987 Jan 15;138(2):635-40 [3098851.001]
  • [Cites] Cancer Res. 1987 Feb 1;47(3):780-6 [3802082.001]
  • [Cites] J Immunol. 1987 Mar 1;138(5):1634-40 [3805727.001]
  • [Cites] Cancer Immunol Immunother. 1989;28(2):153-6 [2783890.001]
  • [Cites] J Biol Response Mod. 1989 Apr;8(2):206-18 [2499665.001]
  • [Cites] J Immunol. 1990 Feb 15;144(4):1425-31 [2303713.001]
  • [Cites] Cancer Immunol Immunother. 1990;31(1):19-27 [1968361.001]
  • [Cites] Acta Oncol. 1990;29(1):47-51 [2310603.001]
  • [Cites] Nature. 1990 Dec 6;348(6301):555-7 [1701033.001]
  • [Cites] Proc Natl Acad Sci U S A. 1991 Apr 1;88(7):2830-4 [1849278.001]
  • [Cites] Clin Exp Metastasis. 1991 Jan-Feb;9(1):57-65 [2015718.001]
  • [Cites] J Immunol. 1991 May 15;146(10):3682-6 [1673988.001]
  • [Cites] J Immunol. 1991 Dec 15;147(12):4398-401 [1684377.001]
  • [Cites] Clin Exp Metastasis. 1992 Mar;10(2):91-7 [1537138.001]
  • [Cites] Int J Cancer. 1993 Mar 12;53(5):829-36 [8449608.001]
  • [Cites] Lymphokine Cytokine Res. 1993 Dec;12(6):439-47 [8123760.001]
  • [Cites] Cytokine. 1993 Nov;5(6):546-55 [8186366.001]
  • [Cites] Oncology. 1994 Mar-Apr;51(2):142-53 [8196898.001]
  • [Cites] Cancer Res. 1994 Jun 15;54(12):3233-6 [7515767.001]
  • [Cites] Haemostasis. 1994 Mar-Apr;24(2):132-8 [7959361.001]
  • [Cites] Biochem Biophys Res Commun. 1994 Nov 15;204(3):1067-73 [7980579.001]
  • [Cites] Shock. 1995 Jan;3(1):1-12 [7850574.001]
  • [Cites] Circ Shock. 1994 Sep;44(1):9-13 [7704939.001]
  • (PMID = 17659374.001).
  • [ISSN] 0004-069X
  • [Journal-full-title] Archivum immunologiae et therapiae experimentalis
  • [ISO-abbreviation] Arch. Immunol. Ther. Exp. (Warsz.)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Cyclohexanes; 0 / Interleukin-6; 0 / Recombinant Proteins; 0 / Sesquiterpenes; 0 / Tumor Necrosis Factor-alpha; 129298-91-5 / O-(chloroacetylcarbamoyl)fumagillol
  • [Other-IDs] NLM/ PMC2766459
  •  go-up   go-down


79. Cahill S, Cryer JR, Otter SJ, Ramesar K: An amelanotic malignant melanoma masquerading as hypergranulation tissue. Foot Ankle Surg; 2009;15(3):158-60
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An amelanotic malignant melanoma masquerading as hypergranulation tissue.
  • We report a case of amelanotic malignant melanoma occurring in the nail sulcus of the hallux, which on initial presentation was mistaken for hypergranulation tissue due to an in-growing toenail.
  • [MeSH-major] Melanoma / physiopathology. Melanoma / surgery. Skin Neoplasms / physiopathology. Skin Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19635427.001).
  • [ISSN] 1460-9584
  • [Journal-full-title] Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons
  • [ISO-abbreviation] Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  •  go-up   go-down


80. Nabeshima T, Kimura K, Kurosaka D: Amelanotic malignant melanoma of the conjunctiva in a young adult. Jpn J Ophthalmol; 2008 Sep-Oct;52(5):407-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the conjunctiva in a young adult.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Melanoma, Amelanotic / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cutis. 2006 Jun;77(6):377-81 [16838771.001]
  • [Cites] Can J Ophthalmol. 1990 Feb;25(1):34-7 [2328436.001]
  • [Cites] Hum Pathol. 1985 Feb;16(2):129-35 [3972395.001]
  • [Cites] Ophthalmology. 1998 Jan;105(1):191-4 [9442798.001]
  • (PMID = 18991044.001).
  • [ISSN] 0021-5155
  • [Journal-full-title] Japanese journal of ophthalmology
  • [ISO-abbreviation] Jpn. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
  •  go-up   go-down


81. Rizvi SA, Amitava AK, Mehdi G, Sharma R, Alam MS: Orbital amelanotic melanoma in xeroderma pigmentosum: a rare association. Indian J Ophthalmol; 2008 Sep-Oct;56(5):421-3
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital amelanotic melanoma in xeroderma pigmentosum: a rare association.
  • Ocular neoplasms occurring in XP in order of frequency are squamous cell carcinoma, basal cell carcinoma and melanoma.
  • Malignant melanomas occur at an early age in patients with XP.
  • We report a case of XP with massive orbital melanoma in an eight-year-old boy which is unique due to its amelanotic presentation confirmed histopathologically.
  • [MeSH-major] Melanoma, Amelanotic / complications. Orbit. Skin Neoplasms / complications. Xeroderma Pigmentosum / complications

  • Genetic Alliance. consumer health - Xeroderma pigmentosum.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Intern Med. 1974 Feb;80(2):221-48 [4811796.001]
  • [Cites] Cancer. 1982 Sep 1;50(5):912-8 [6807528.001]
  • [Cites] Arch Dermatol. 1987 Feb;123(2):241-50 [3545087.001]
  • [Cites] Tunis Med. 2006 Sep;84(9):542-4 [17263199.001]
  • [Cites] Br J Ophthalmol. 1993 Sep;77(9):597-8 [8218060.001]
  • [Cites] Br J Ophthalmol. 1994 Apr;78(4):295-7 [8199117.001]
  • [Cites] Br J Dermatol. 1965 May;77:261-76 [14283428.001]
  • [Cites] Arch Ophthalmol. 1989 Mar;107(3):402-7 [2923565.001]
  • (PMID = 18711275.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2636150
  •  go-up   go-down


82. Mesa M, Quesada JL, Piñas J: Metastasis of amelanotic melanoma of unknown origin in the parotid gland. Br J Oral Maxillofac Surg; 2009 Oct;47(7):569-71
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasis of amelanotic melanoma of unknown origin in the parotid gland.
  • We report a rare case of metastasis of an amelanotic melanoma of the parotid gland.
  • To our knowledge this is the first report of a metastasis of an amelanotic melanoma in a parotid lymph node.
  • [MeSH-major] Melanoma, Amelanotic / secondary. Neoplasms, Unknown Primary / pathology. Parotid Neoplasms / secondary
  • [MeSH-minor] Aged. Antigens, Neoplasm / analysis. Biopsy, Fine-Needle. Female. Humans. Lymphatic Metastasis / pathology. Magnetic Resonance Imaging. Melanoma-Specific Antigens. Neoplasm Proteins / analysis. S100 Proteins / analysis. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19167137.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  •  go-up   go-down


83. Gelpi E, Popovic M, Preusser M, Budka H, Hainfellner J: Pleomorphic xanthoastrocytoma with anaplastic features presenting without GFAP immunoreactivity: implications for differential diagnosis. Neuropathology; 2005 Sep;25(3):241-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In these cases, the differential diagnosis needs to exclude other malignancies, for example, glioblastoma or malignant fibrous histiocytoma.
  • These features led to the tentative diagnosis of amelanotic melanoma, and the patient was irradiated.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry / methods. Melanoma / pathology. Microscopy, Confocal. Microscopy, Electron, Transmission. Neoplasm Recurrence, Local / metabolism. Neoplasm Recurrence, Local / pathology

  • Genetic Alliance. consumer health - Pleomorphic xanthoastrocytoma.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16193842.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein
  •  go-up   go-down


84. Nakamoto T, Inoue Y, Ueki T, Niimi N, Iwasaki Y: Primary amelanotic malignant melanoma of the female urethra. Int J Urol; 2007 Feb;14(2):153-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic malignant melanoma of the female urethra.
  • The case is reported of amelanotic malignant melanoma of the female urethra mimicking urethral caruncle.
  • Urethral carunclectomy was performed, but histological diagnosis was amelanotic malignant melanoma.
  • [MeSH-major] Melanoma, Amelanotic. Urethral Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17302574.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


85. Cichorek M, Kozłowska K, Wachulska M, Zielińska K: Spontaneous apoptosis of melanotic and amelanotic melanoma cells in different phases of cell cycle: relation to tumor growth. Folia Histochem Cytobiol; 2006;44(1):31-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous apoptosis of melanotic and amelanotic melanoma cells in different phases of cell cycle: relation to tumor growth.
  • Since the spontaneous alteration of native melanotic (Ma) into amelanotic (Ab) transplantable melanoma line it has been observed that this alteration is accompanied by the acceleration of growth of Ab line.
  • Apoptosis estimated by the TUNEL method, alterations in the plasma membrane structure (annexin V staining), changes in the mitochondrial transmembrane potential--delta psi m (JC-1 staining) showed that amelanotic melanoma cells have decreased ability to undergo spontaneous apoptosis.
  • The obtained results showing that in the native melanotic line about 30% of cells are in S+G2/M phases and that 33% of these cells undergo apoptosis could lead to the conclusion that the slower growth of this melanoma line is the result of lower proliferation activity and higher rate of apoptosis of these tumor cells.
  • The number of cells in S+G2/M phases in amelanotic melanoma line increases up to 40% and only 7% of them undergo apoptosis.
  • This observation seems to suggest that the expansive growth of this melanoma line depends mainly on the decreased ability to undergo spontaneous apoptosis, especially in case of cells from S+G2/M phases.
  • Moreover, the obtained results indicate that alteration of melanotic line into amelanotic one, accompanied by differences in many biological features also concerns basic cell processes such as cell cycle and cell death.

  • MedlinePlus Health Information. consumer health - Melanoma.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16584089.001).
  • [ISSN] 0239-8508
  • [Journal-full-title] Folia histochemica et cytobiologica
  • [ISO-abbreviation] Folia Histochem. Cytobiol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Annexin A5; 0 / Phosphatidylserines
  •  go-up   go-down


86. Sinicropi MS, Caruso A, Conforti F, Marrelli M, El Kashef H, Lancelot JC, Rault S, Statti GA, Menichini F: Synthesis, inhibition of NO production and antiproliferative activities of some indole derivatives. J Enzyme Inhib Med Chem; 2009 Oct;24(5):1148-53
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The compounds prepared were evaluated for their inhibition of NO production, antioxidant activity and also for their ability to inhibit in vitro the growth of four human tumor cell lines: large lung carcinoma (COR-L23), alveolar basal epithelial carcinoma (A549), amelanotic melanoma (C32) and melanoma (A375).
  • Compound 5a was the most active against melanotic melanoma (IC(50) = 11.8 microM) while the other compounds exhibited weak cytotoxicity with IC(50) values >50 microM on all cell lines.

  • Hazardous Substances Data Bank. NITRIC OXIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19555184.001).
  • [ISSN] 1475-6374
  • [Journal-full-title] Journal of enzyme inhibition and medicinal chemistry
  • [ISO-abbreviation] J Enzyme Inhib Med Chem
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Indoles; 0 / Pyrans; 31C4KY9ESH / Nitric Oxide
  •  go-up   go-down


87. De Simone P, Gelin M, El Nakadi I: Amelanotic malignant melanoma of the esophagus. Report of a case. Minerva Chir; 2006 Feb;61(1):45-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the esophagus. Report of a case.
  • Primary malignant melanomas of the esophagus are rare neoplasms with aggressive behavior and tendency to lymphatic and hematogenous spread.
  • We report on a patient affected with a primary amelanotic melanoma of the esophagus synchronous to a squamous cell carcinoma of the epiglottis and treated by subtotal esophagectomy.
  • Review of patient's medical history and exploration of skin and mucous membranes failed to reveal malignant lesions and definitive diagnosis was primary amelanotic malignant melanoma of the esophagus.
  • The patient died 16 months after surgery of disseminated disease.
  • In conclusion the present case confirms that primary malignant melanomas of the esophagus have a dismal outcome even in cases of early-stage lesions amenable to surgical resection.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Epiglottis. Esophageal Neoplasms / pathology. Laryngeal Neoplasms / pathology. Melanoma / pathology. Neoplasms, Multiple Primary / pathology

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16568022.001).
  • [ISSN] 0026-4733
  • [Journal-full-title] Minerva chirurgica
  • [ISO-abbreviation] Minerva Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


88. Silver EA, Hofmann AE, Williams D, Srolovitz H, Tahiri Y, Khanna M: Large amelanotic melanoma and vitiligo. Arch Dermatol; 2009 Oct;145(10):1198-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large amelanotic melanoma and vitiligo.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Palliative Care. Skin Neoplasms / pathology. Vitiligo / diagnosis


89. Siddaraju N, Yaranal PJ, Mishra MM, Soundararaghavan J: Fine needle aspiration cytology in recurrent amelanotic melanoma: a case report. Acta Cytol; 2007 Sep-Oct;51(5):829-32
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration cytology in recurrent amelanotic melanoma: a case report.
  • BACKGROUND: Amelanotic melanoma can mimic a wide variety of epithelial and nonepithelial malignant tumors.
  • Varied cytomorphology of melanoma has been described on exfoliative and fine needle aspiration cytology (FNAC).
  • We report a case of recurrent amelanotic melanoma to highlight its varied cytomorphologic features, which may cause diagnostic problems on cytologic and on histologic examinations.
  • FNAC revealed malignant cells with highly varied morphology with plasmacytoid and pleomorphic malignant cells with occasional fibrocollagenous tissue strands showing adherent neoplastic cells.
  • A cytologic diagnosis of pleomorphic malignant tumor was suggested, and the original histologic slides were reviewed; they showed a striking alveolar pattern that vaguely resembled an alveolar rhabdomyosarcoma.
  • A final diagnosis of amelanotic melanoma was made.
  • CONCLUSION: Awareness of the highly varied cytomorphology of amelanotic melanoma minimizes the diagnostic difficulty on fine needle aspiration smears.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Neoplasm Recurrence, Local / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17910357.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


90. Menichini F, Tundis R, Loizzo MR, Bonesi M, Provenzano E, de Cindio B, Menichini F: In vitro photo-induced cytotoxic activity of Citrus bergamia and C. medica L. cv. Diamante peel essential oils and identified active coumarins. Pharm Biol; 2010 Sep;48(9):1059-65
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In order to evaluate the cytotoxic activity two melanoma models, such as amelanotic melanoma C32 and malignant melanoma A375, were used.
  • This phototoxicity may be considered as a treatment option in some cases of lentigo maligna or lentigo maligna melanoma.
  • [MeSH-minor] Cell Line, Tumor. Cell Survival / drug effects. Cell Survival / radiation effects. Drug Discovery. Drug Evaluation, Preclinical. Gas Chromatography-Mass Spectrometry. Humans. Inhibitory Concentration 50. Melanoma / drug therapy. Melanoma, Amelanotic / drug therapy. Methoxsalen / analogs & derivatives. Methoxsalen / analysis. Methoxsalen / chemistry. Methoxsalen / pharmacology. Methoxsalen / radiation effects. Photochemotherapy. Phytotherapy. Time Factors. Ultraviolet Rays

  • Hazardous Substances Data Bank. 8-METHOXYPSORALEN .
  • Hazardous Substances Data Bank. 5-METHOXYPSORALEN .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20690896.001).
  • [ISSN] 1744-5116
  • [Journal-full-title] Pharmaceutical biology
  • [ISO-abbreviation] Pharm Biol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Coumarins; 0 / Oils, Volatile; 4FVK84C92X / 5-methoxypsoralen; JWE1QQ247N / 5,7-dimethoxycoumarin; U4VJ29L7BQ / Methoxsalen
  •  go-up   go-down


91. Bapst JP, Calame M, Tanner H, Eberle AN: Glycosylated DOTA-alpha-melanocyte-stimulating hormone analogues for melanoma targeting: influence of the site of glycosylation on in vivo biodistribution. Bioconjug Chem; 2009 May 20;20(5):984-93
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Glycosylated DOTA-alpha-melanocyte-stimulating hormone analogues for melanoma targeting: influence of the site of glycosylation on in vivo biodistribution.
  • alpha-Melanocyte-stimulating hormone (alpha-MSH) is known to bind to the melanocortin receptor 1 (MC1R) which is overexpressed on melanotic and amelanotic melanoma cells. alpha-MSH analogues are potential candidates for specific targeting of melanoma metastases.
  • The peptides were evaluated in vitro for MC1R binding and bioactivity and, after labeling with (111)In, for in vitro cellular uptake and in vivo tissue distribution in mice carrying B16F1 melanoma tumors.
  • The glycopeptides showed excellent binding affinities in the low nanomolar to subnanomolar range using both murine and human melanoma cell lines.
  • [MeSH-major] Glycopeptides / metabolism. Glycopeptides / pharmacokinetics. Heterocyclic Compounds, 1-Ring / chemistry. Melanoma / metabolism. alpha-MSH / analogs & derivatives

  • MedlinePlus Health Information. consumer health - Melanoma.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19388674.001).
  • [ISSN] 1520-4812
  • [Journal-full-title] Bioconjugate chemistry
  • [ISO-abbreviation] Bioconjug. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carbohydrates; 0 / Glycopeptides; 0 / Heterocyclic Compounds, 1-Ring; 0 / Peptide Fragments; 0 / Receptor, Melanocortin, Type 1; 0 / alpha-MSH (4-11), acetyl0Nle(4)-Asp(5)-Phe(7)-; 581-05-5 / alpha-MSH; 60239-18-1 / 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
  •  go-up   go-down


92. Oburu E, Gregori A: Relearning the lesson -- amelanotic malignant melanoma: a case report. J Med Case Rep; 2008;2:31
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relearning the lesson -- amelanotic malignant melanoma: a case report.
  • Although not as common as the other melanomas, amelanotic melanoma often evades diagnosis by masquerading as other pathology.
  • We present a patient who was diagnosed and managed as having paronychia of the middle finger while in actual fact he had a subungual amelanotic melanoma.
  • Our case underlies the importance of early recognition and referral of this rare but malignant lesion by primary care physicians.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Dermatol Surg. 1999 May;25(5):408-11 [10469082.001]
  • [Cites] J R Coll Surg Edinb. 2002 Aug;47(4):638-40 [12363192.001]
  • [Cites] Skinmed. 2004 Jan-Feb;3(1):41-4 [14724412.001]
  • [Cites] Semin Cutan Med Surg. 1997 Jun;16(2):122-30 [9220551.001]
  • [Cites] Br J Plast Surg. 1992 May-Jun;45(4):275-8 [1623342.001]
  • [Cites] Cutis. 1980 Feb;25(2):164-6, 168 [7357883.001]
  • [Cites] J Am Acad Dermatol. 1992 Jun;26(6):914-9 [1607408.001]
  • (PMID = 18237392.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2267474
  •  go-up   go-down


93. Jeong TJ, Lee EJ, Haw S, Shin MK, Haw CR: Coexistence of amelanotic melanoma and liposarcoma. Ann Dermatol; 2009 Nov;21(4):409-12
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coexistence of amelanotic melanoma and liposarcoma.
  • An amelanotic malignant melanoma is characterized by little or no pigment.
  • We encountered a case of amelanotic melanoma with a concurrent liposarcoma.
  • These findings were consistent with amelanotic melanoma.
  • However, an association between melanoma and liposarcoma is rare.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer. 2001 Apr 1;91(7):1363-71 [11283938.001]
  • [Cites] Natl Cancer Inst Monogr. 1985 Dec;68:3-9 [4088304.001]
  • [Cites] Science. 1995 Sep 1;269(5228):1281-4 [7652577.001]
  • [Cites] J Am Acad Dermatol. 1994 Aug;31(2 Pt 1):216-9 [8040404.001]
  • [Cites] Cancer. 1997 Feb 15;79(4):843-8 [9024723.001]
  • [Cites] Int J Cancer. 2006 Aug 15;119(4):909-14 [16557572.001]
  • [Cites] J Surg Oncol. 2009 Feb 1;99(2):114-8 [19034932.001]
  • [Cites] J Natl Cancer Inst. 2002 Jun 19;94(12):894-903 [12072543.001]
  • [Cites] Oncogene. 2003 May 19;22(20):3092-8 [12789286.001]
  • [Cites] J Pathol. 2004 Jan;202(1):95-102 [14694526.001]
  • [Cites] Br J Dermatol. 2004 Jun;150(6):1117-24 [15214897.001]
  • [Cites] J Pathol. 1998 Jun;185(2):188-90 [9713346.001]
  • (PMID = 20523835.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2861252
  • [Keywords] NOTNLM ; Amelanotic melanoma / Liposarcoma
  •  go-up   go-down


94. Soucek P, Cihelkova I: Primary treatment of choroidal amelanotic melanoma with photodynamic therapy--comment. Clin Exp Ophthalmol; 2006 Sep-Oct;34(7):721; author reply 721-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary treatment of choroidal amelanotic melanoma with photodynamic therapy--comment.
  • [MeSH-major] Choroid Neoplasms / drug therapy. Melanoma, Amelanotic / drug therapy. Photochemotherapy. Photosensitizing Agents / therapeutic use. Porphyrins / therapeutic use

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Clin Exp Ophthalmol. 2005 Oct;33(5):548-9 [16181294.001]
  • (PMID = 16970777.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Porphyrins; 129497-78-5 / verteporfin
  •  go-up   go-down


95. Suzuki Y, Aoyama N, Minamide J, Takata K, Ogata T: Amelanotic malignant melanoma of the esophagus: report of a patient with recurrence successfully treated with chemoendocrine therapy. Int J Clin Oncol; 2005 Jun;10(3):204-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the esophagus: report of a patient with recurrence successfully treated with chemoendocrine therapy.
  • We report a case of primary amelanotic malignant melanoma of the esophagus, an extremely rare disease.
  • In general, the prognosis of esophageal malignant melanoma is very poor.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Esophageal Neoplasms / drug therapy. Melanoma / drug therapy

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
  • Hazardous Substances Data Bank. DACARBAZINE .
  • Hazardous Substances Data Bank. VINCRISTINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Natl Cancer Inst. 1990 Mar 7;82(5):361-70 [2406452.001]
  • [Cites] Gastroenterol Jpn. 1991 Apr;26(2):209-12 [2040402.001]
  • [Cites] Jpn J Clin Oncol. 1990 Sep;20(3):286-95 [2255105.001]
  • [Cites] Thorax. 1991 May;46(5):397-8 [2068703.001]
  • [Cites] Jpn J Clin Oncol. 1998 Dec;28(12):758-61 [9879295.001]
  • [Cites] Eur J Cancer Clin Oncol. 1984 Jul;20(7):983-5 [6611266.001]
  • [Cites] J Immunol. 1983 Dec;131(6):2767-71 [6605988.001]
  • [Cites] Surg Today. 1993;23(9):820-4 [8219617.001]
  • [Cites] Trop Gastroenterol. 2000 Oct-Dec;21(4):185-7 [11194582.001]
  • [Cites] N Engl J Med. 1979 Nov 29;301(22):1241-2 [503125.001]
  • [Cites] Yonsei Med J. 1998 Oct;39(5):468-73 [9821797.001]
  • [Cites] N Engl J Med. 1992 Aug 20;327(8):516-23 [1635566.001]
  • [Cites] Dis Esophagus. 2000;13(4):320-3 [11284983.001]
  • [Cites] Cancer Treat Rep. 1984 Nov;68(11):1403-5 [6541973.001]
  • [Cites] Cancer. 1989 Apr 1;63(7):1292-5 [2920358.001]
  • (PMID = 15990972.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0S726V972K / Nimustine; 5J49Q6B70F / Vincristine; 77238-31-4 / Interferon-beta; 7GR28W0FJI / Dacarbazine; Q20Q21Q62J / Cisplatin
  •  go-up   go-down


96. Ludwig T, Fakih S, Bertram H, Krebs B, Oberleithner H: New imidazole-coordinated chemotherapeutics with low epithelial toxicity. Cell Biochem Biophys; 2006;45(1):31-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The chlorine substituted NICE had no effect on epithelial integrity but markedly cytotoxic activity against amelanotic melanoma cells.

  • Hazardous Substances Data Bank. CARBOPLATIN .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16679562.001).
  • [ISSN] 1085-9195
  • [Journal-full-title] Cell biochemistry and biophysics
  • [ISO-abbreviation] Cell Biochem. Biophys.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Imidazoles; 0 / Ligands; 0 / Organic Cation Transport Proteins; 0 / Organoplatinum Compounds; BG3F62OND5 / Carboplatin; EC 3.4.22.- / Caspase 3; EC 3.4.22.- / Caspases
  •  go-up   go-down


97. Babilas P, Liebsch G, Schacht V, Klimant I, Wolfbeis OS, Szeimies RM, Abels C: In vivo phosphorescence imaging of pO2 using planar oxygen sensors. Microcirculation; 2005 Sep;12(6):477-87
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Due to intrinsically referencing via lifetime encoding there was no modification of the sensor response in vivo in the dorsal skinfold chamber model with amelanotic melanoma (A-MEL-3) in awake hamsters when compared to the in vitro calibration. pO(2) measurements over normal tissue (25.8 +/- 5.1 mm Hg) and tumor tissue (9.2 +/- 5.1 mm Hg) were in excellent agreement with previous results obtained in this model using a surface multiwire electrode.
  • [MeSH-major] Luminescent Measurements. Melanoma, Experimental / metabolism. Metalloporphyrins / analysis. Oximetry. Oxygen Consumption

  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16147465.001).
  • [ISSN] 1073-9688
  • [Journal-full-title] Microcirculation (New York, N.Y. : 1994)
  • [ISO-abbreviation] Microcirculation
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Metalloporphyrins; 0 / Polystyrenes
  •  go-up   go-down


98. Ikeda K, Tate G, Iezumi K, Suzuki T, Kitamura T, Mitsuya T: Effusion cytomorphology and immunocytochemistry of malignant melanoma: five cases of melanotic melanoma and one case of amelanotic melanoma. Diagn Cytopathol; 2009 Jul;37(7):516-21
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effusion cytomorphology and immunocytochemistry of malignant melanoma: five cases of melanotic melanoma and one case of amelanotic melanoma.
  • Effusion cytological analyses of amelanotic malignant melanoma (AMM) are very rare and no concise description of AMM related cytomorphologic features using effusion have been reported.
  • Here, we report the cytomorphological, immunohistochemical, and immunocytochemical findings in the effusion cytology of six cases of malignant melanoma (MM), one case of AMM, and five cases of melanotic malignant melanoma.
  • With regard to the immunohistochemistry findings, all six cases of melanoma were positive for Melan-A/MART-1, HBME-1, and S-100.
  • In the immunohistochemistry analyses, five of six cases of melanoma were positive for WT-1, as was the AMM specimen.
  • Furthermore, because the effusion analysis of malignant mesothelioma proved positive for WT-1, it should be noted that WT-1 effusion analysis is not an appropriate means to distinguish between MM and malignant mesothelioma.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / metabolism. Neoplasm Proteins / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 19301358.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
  •  go-up   go-down


99. Sbai MA, Boussen M, Mankai I, Souissi M, Day SC, Korbi A, Tebib M: [Amelanotic malignant melanoma of the great toe]. Tunis Med; 2010 Feb;88(2):130-1
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Amelanotic malignant melanoma of the great toe].
  • [Transliterated title] Mélanome malin achromique de l'hallux.
  • [MeSH-major] Hallux / surgery. Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20415177.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Tunisia
  •  go-up   go-down


100. Baran R: The red nail--always benign? Actas Dermosifiliogr; 2009 Nov;100 Suppl 1:106-13
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Only the former type can show histologically Bowen's disease or an amelanotic melanoma.
  • Among the polydactylous type, the nosologic position of the acantholytic and dyskeratotic naevus versus Darier's disease is still controversial.
  • Acantholytic epidermolysis bullosa looks like bullous Darier's disease, and acrokeratosis of Hopf may present also red longitudinal streaks.
  • Subungual warty dyskeratoma is rare, but other dermatoses such as lichen planus, psoriasis, mail melanoma and various tumours have to be ruled out.
  • Finally nail involvement in amyloidosis may precede the other signs of this systemic disease.

  • MedlinePlus Health Information. consumer health - Nail Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20096204.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Spain
  •  go-up   go-down






Advertisement