[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 174
1. Jeong TJ, Lee EJ, Haw S, Shin MK, Haw CR: Coexistence of amelanotic melanoma and liposarcoma. Ann Dermatol; 2009 Nov;21(4):409-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coexistence of amelanotic melanoma and liposarcoma.
  • An amelanotic malignant melanoma is characterized by little or no pigment.
  • We encountered a case of amelanotic melanoma with a concurrent liposarcoma.
  • These findings were consistent with amelanotic melanoma.
  • However, an association between melanoma and liposarcoma is rare.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer. 2001 Apr 1;91(7):1363-71 [11283938.001]
  • [Cites] Natl Cancer Inst Monogr. 1985 Dec;68:3-9 [4088304.001]
  • [Cites] Science. 1995 Sep 1;269(5228):1281-4 [7652577.001]
  • [Cites] J Am Acad Dermatol. 1994 Aug;31(2 Pt 1):216-9 [8040404.001]
  • [Cites] Cancer. 1997 Feb 15;79(4):843-8 [9024723.001]
  • [Cites] Int J Cancer. 2006 Aug 15;119(4):909-14 [16557572.001]
  • [Cites] J Surg Oncol. 2009 Feb 1;99(2):114-8 [19034932.001]
  • [Cites] J Natl Cancer Inst. 2002 Jun 19;94(12):894-903 [12072543.001]
  • [Cites] Oncogene. 2003 May 19;22(20):3092-8 [12789286.001]
  • [Cites] J Pathol. 2004 Jan;202(1):95-102 [14694526.001]
  • [Cites] Br J Dermatol. 2004 Jun;150(6):1117-24 [15214897.001]
  • [Cites] J Pathol. 1998 Jun;185(2):188-90 [9713346.001]
  • (PMID = 20523835.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2861252
  • [Keywords] NOTNLM ; Amelanotic melanoma / Liposarcoma
  •  go-up   go-down


2. Ohata Y, Haga T, Ogata S, Nakanishi K, Kawai T: Malignant amelanotic melanoma of the pleura without primary skin lesion:an autopsy case report. Acta Med Okayama; 2009 Dec;63(6):379-84
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant amelanotic melanoma of the pleura without primary skin lesion:an autopsy case report.
  • Melanoma metastasizing to the lungs is common, but primary pulmonary or pleural melanoma is extremely rare.
  • We present an autopsy case of malignant melanoma of the pleura without primary skin lesion in a 49-year-old man.
  • At autopsy, a yellow-white tumor located primarily in the right visceral pleura (diagnosed as an amelanotic melanoma) was found to have invaded into the right lung, right parietal pleura, and right diaphragm, and to have metastasized into the left lung and visceral pleura, thyroid, and left adrenal gland.
  • Immuno-histochemical examination for S100 and HMB-45 would thus appear to be useful for the diagnosis of an amelanotic melanoma.
  • [MeSH-major] Lung Neoplasms. Melanoma, Amelanotic. Pleura / pathology. Skin Neoplasms

  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20035295.001).
  • [ISSN] 0386-300X
  • [Journal-full-title] Acta medica Okayama
  • [ISO-abbreviation] Acta Med. Okayama
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


3. Morita N, Hiratsuka J, Kondoh H, Uno M, Asano T, Niki Y, Sakurai Y, Ono K, Harada T, Imajo Y: Improvement of the tumor-suppressive effect of boron neutron capture therapy for amelanotic melanoma by intratumoral injection of the tyrosinase gene. Cancer Res; 2006 Apr 1;66(7):3747-53
Hazardous Substances Data Bank. (L)-Phenylalanine .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Improvement of the tumor-suppressive effect of boron neutron capture therapy for amelanotic melanoma by intratumoral injection of the tyrosinase gene.
  • In melanoma, (10)B-para-boronophenylalanine (BPA) accumulation is proportional to melanin-producing activity.
  • This study was done to confirm enhancement of the tumor-suppressive effect of BNCT on amelanotic melanoma by intratumoral injection of the tyrosinase gene.
  • D178 or FF amelanotic melanomas were implanted s.c. in Syrian hamsters.
  • In vivo transfection with the tyrosinase gene increased BPA accumulation in the tumors, the BNCT tumor-suppressive effect on amelanotic melanoma being significantly enhanced.
  • These findings suggest a potential new clinical strategy for the treatment of amelanotic melanoma with BNCT.
  • [MeSH-major] Boron Neutron Capture Therapy / methods. Genetic Therapy / methods. Melanoma, Amelanotic / enzymology. Melanoma, Amelanotic / radiotherapy. Monophenol Monooxygenase / genetics. Skin Neoplasms / enzymology. Skin Neoplasms / radiotherapy

  • MedlinePlus Health Information. consumer health - Genes and Gene Therapy.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • Hazardous Substances Data Bank. BORON COMPOUNDS .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16585201.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Boron Compounds; 0 / Radiation-Sensitizing Agents; 47E5O17Y3R / Phenylalanine; EC 1.14.18.1 / Monophenol Monooxygenase; UID84303EL / 4-boronophenylalanine
  •  go-up   go-down


Advertisement
4. Nalamwar R, Kharkar V, Mahajan S, Chikhalkar S, Khopkar U: Nodular amelanotic melanoma. Indian J Dermatol Venereol Leprol; 2010 May-Jun;76(3):273-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nodular amelanotic melanoma.
  • Malignant cells were positive for S100 and human melanin black 45(HMB 45).
  • Hence, a diagnosis of amelanotic melanoma (AM)--Clarke level IV and TNM stage III was reached.
  • Fine needle aspiration cytology (FNAC) from the right inguinal nodes confirmed metastasis of melanoma.
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / surgery. Skin Neoplasms / diagnosis. Skin Neoplasms / surgery

  • Genetic Alliance. consumer health - Nodular melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20445300.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


5. Peterson J, Rowley M: Rhinophymatous amelanotic melanoma. Cutis; 2007 May;79(5):383-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rhinophymatous amelanotic melanoma.
  • Amelanotic melanomas are well-known to mimic other dermatologic lesions and often result in delayed diagnosis and treatment.
  • We report a case of an unusual presentation of amelanotic melanoma with an appearance similar to rhinophyma.
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Skin Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17569401.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


6. Oburu E, Gregori A: Relearning the lesson -- amelanotic malignant melanoma: a case report. J Med Case Rep; 2008;2:31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relearning the lesson -- amelanotic malignant melanoma: a case report.
  • Although not as common as the other melanomas, amelanotic melanoma often evades diagnosis by masquerading as other pathology.
  • We present a patient who was diagnosed and managed as having paronychia of the middle finger while in actual fact he had a subungual amelanotic melanoma.
  • Our case underlies the importance of early recognition and referral of this rare but malignant lesion by primary care physicians.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Dermatol Surg. 1999 May;25(5):408-11 [10469082.001]
  • [Cites] J R Coll Surg Edinb. 2002 Aug;47(4):638-40 [12363192.001]
  • [Cites] Skinmed. 2004 Jan-Feb;3(1):41-4 [14724412.001]
  • [Cites] Semin Cutan Med Surg. 1997 Jun;16(2):122-30 [9220551.001]
  • [Cites] Br J Plast Surg. 1992 May-Jun;45(4):275-8 [1623342.001]
  • [Cites] Cutis. 1980 Feb;25(2):164-6, 168 [7357883.001]
  • [Cites] J Am Acad Dermatol. 1992 Jun;26(6):914-9 [1607408.001]
  • (PMID = 18237392.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2267474
  •  go-up   go-down


7. Lazarević V, Tiodorović J, Tiodorović-Zivković D, Stanojević M, Popović D, Janković A: Immunophenotyping of amelanotic melanoma. A case report. Acta Dermatovenerol Alp Pannonica Adriat; 2006 Sep;15(3):141-3
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunophenotyping of amelanotic melanoma. A case report.
  • Amelanotic malignant melanoma (AMM) is a subtype of cutaneous melanoma with little or no pigment upon visual inspection.
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Skin Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17053850.001).
  • [ISSN] 1318-4458
  • [Journal-full-title] Acta dermatovenerologica Alpina, Pannonica, et Adriatica
  • [ISO-abbreviation] Acta Dermatovenerol Alp Pannonica Adriat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Slovenia
  • [Chemical-registry-number] 0 / Antibodies; 0 / Antibodies, Monoclonal; 0 / S100 Proteins; 68238-35-7 / Keratins
  •  go-up   go-down


8. Karnwal A, Hadjihannas E, Sherif A, Grumett S, Karnwal S, Mathews J: Amelanotic melanoma presenting with cervical lymphadenopathy. BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic melanoma presenting with cervical lymphadenopathy.
  • We present a rare case of an amelanotic melanoma of unknown primary presenting with cervical lymphadenopathy.
  • Histological examination of the lymph nodal mass confirmed the diagnosis of a metastatic amelanotic melanoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Surg Gynecol Obstet. 1963 Sep;117:341-5 [14080349.001]
  • [Cites] Melanoma Res. 2005 Feb;15(1):77-82 [15714125.001]
  • [Cites] Cancer. 2006 May 1;106(9):2012-20 [16568458.001]
  • [Cites] Otolaryngol Head Neck Surg. 1981 Jul-Aug;89(4):594-8 [6793970.001]
  • [Cites] Cancer. 1997 May 1;79(9):1816-21 [9129001.001]
  • [Cites] Clin Otolaryngol Allied Sci. 1994 Apr;19(2):161-5 [8026097.001]
  • (PMID = 21686931.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028389
  •  go-up   go-down


9. Castillo O, Frisancho O, Palomino A: [Cecal amelanotic melanoma]. Rev Gastroenterol Peru; 2010 Oct-Dec;30(4):368-71
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cecal amelanotic melanoma].
  • [Transliterated title] Melanoma amelanótico en ciego.
  • Subsequently, we confirmed the presence of red blood in stools, like enterorrhagia and underwent a colonoscopy, in which two elevated lesions were found in the cecum: a pedunculated (with active bleeding, oozing) and other sessile; both were removed. the pathology showed that corresponded to amelanotic melanoma in cecal region.
  • Physical examination revealed no malignant skin lesions.
  • We report this case, because gastrointestinal bleeding is an unusual clinical presentation of malignant melanoma.
  • [MeSH-major] Cecal Neoplasms / pathology. Melanoma / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21263766.001).
  • [ISSN] 1022-5129
  • [Journal-full-title] Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
  • [ISO-abbreviation] Rev Gastroenterol Peru
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Peru
  •  go-up   go-down


10. Duong HV, McLean IW, Beahm DE: Bilateral diffuse melanocytic proliferation associated with ovarian carcinoma and metastatic malignant amelanotic melanoma. Am J Ophthalmol; 2006 Oct;142(4):693-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral diffuse melanocytic proliferation associated with ovarian carcinoma and metastatic malignant amelanotic melanoma.
  • PURPOSE: To report a case of metastatic malignant amelanotic melanoma to the skin from a patient diagnosed with bilateral diffuse uveal melanocytic proliferation (BDUMP).
  • This dermatological finding is a unique phenomenon associated with BDUMP.
  • RESULTS: The hematoxylin and eosin, S-100, and HMB-45 stains were consistent with metastatic malignant amelanotic melanoma to the skin.
  • [MeSH-major] Melanocytes / pathology. Melanoma, Amelanotic / secondary. Ovarian Neoplasms / pathology. Paraneoplastic Syndromes / pathology. Skin Neoplasms / secondary. Uveal Diseases / diagnosis
  • [MeSH-minor] Aged. Antigens, Neoplasm / analysis. Cell Proliferation. Eye Enucleation. Female. Humans. Immunohistochemistry. Melanoma-Specific Antigens. Neoplasm Proteins / analysis. Retrospective Studies. S100 Proteins / analysis

  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17011873.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  •  go-up   go-down


11. An J, Li B, Wu L, Lu H, Li N: Primary malignant amelanotic melanoma of the female genital tract: report of two cases and review of literature. Melanoma Res; 2009 Aug;19(4):267-70
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for amelanotic melanoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary malignant amelanotic melanoma of the female genital tract: report of two cases and review of literature.
  • Primary amelanotic melanoma of the female genital tract usually has a poor outcome as a consequence of delayed diagnosis and lack of standardized treatment.
  • We report two cases of this disease originating in the vulva and uterine cervix, respectively.
  • Compared with amelanotic melanoma of the female genital tract of the vulva, disease of the cervix is more likely to be misdiagnosed, identified at a later stage, and have a poorer outcome.
  • [MeSH-major] Melanoma, Amelanotic. Uterine Cervical Neoplasms. Vulvar Neoplasms


12. Arican O, Sasmaz S, Coban YK, Ciralik H: Subungual amelanotic malignant melanoma. Saudi Med J; 2006 Feb;27(2):247-9
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subungual amelanotic malignant melanoma.
  • Histopathological examination of toenail specimen revealed the presence of nests of atypical tumor cells that led to the diagnosis of amelanotic malignant melanoma.
  • As this disease is seen very rarely, it can be misdiagnosed.
  • We presented a case of subungual amelanotic melanoma, as it is rare disease, early and correct diagnosis is very important.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16501687.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
  •  go-up   go-down


13. Hillenbrand A, Barth TF, Henne-Bruns D, Formentini A: Anorectal amelanotic melanoma. Colorectal Dis; 2008 Jul;10(6):612-5
MedlinePlus Health Information. consumer health - Anal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anorectal amelanotic melanoma.
  • OBJECTIVE: Anorectal melanoma is a rare, highly malignant tumour with a poor 5 year survival of 10%.
  • Most anorectal melanomas have gross and/or histologic pigmentation, however about 30% of anorectal melanomas are amelanotic.
  • METHOD: We report three cases of amelanotic anorectal melanomas and integrate our data with six case reports of amelanotic malignant melanoma from the literature.
  • Further we compare clinicopathological data and clinical outcome with large series of anorectal melanomas (both, amelanotic and pigmentated).
  • A tumour thickness of < 4 mm was correlated with long-term disease-free survival, whereas tumour thickness of 4 mm or more was correlated with systemic recurrence.
  • CONCLUSION: Early diagnosis is key for efficient treatment and improved survival rate for patients with this unusual variant of melanoma.
  • There is no difference in terms of age, time of diagnosis, stage and survival between pigmented and amelanotic anorectal melanoma.
  • [MeSH-major] Anus Neoplasms. Melanoma, Amelanotic. Rectal Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17944970.001).
  • [ISSN] 1463-1318
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  •  go-up   go-down


14. de Giorgi V, Sestini S, Massi D, Maio V, Giannotti B: Dermoscopy for "true" amelanotic melanoma: a clinical dermoscopic-pathologic case study. J Am Acad Dermatol; 2006 Feb;54(2):341-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermoscopy for "true" amelanotic melanoma: a clinical dermoscopic-pathologic case study.
  • Completely amelanotic melanomas are rare and therefore often misclassified, with tragic consequences for patients.
  • We present a case of "true" amelanotic melanoma on the forehead of an 89-year-old man, which clinically mimicked squamous cell carcinoma.
  • The dermoscopic diagnostic algorithms routinely used for pigmented lesions are not helpful in diagnosing amelanotic melanoma because they are based on specific parameters not normally seen in amelanotic lesions.
  • In the light of our experience, pattern analysis is the most reliable method for diagnosing these particular lesions correctly because it allows in-depth morphologic analysis of the few parameters found.
  • [MeSH-major] Dermoscopy. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Am Acad Dermatol. 2006 Oct;55(4):728 [17010767.001]
  • (PMID = 16443072.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. Sayk F, Mahnken A, Stellmacher F, Dalhoff K, Merz H: [Cancer-to-cancer metastasis: amelanotic melanoma into renal cell carcinoma]. Dtsch Med Wochenschr; 2010 Mar;135(11):507-10
MedlinePlus Health Information. consumer health - Kidney Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cancer-to-cancer metastasis: amelanotic melanoma into renal cell carcinoma].
  • DIAGNOSIS: The autopsy revealed that he was affected by two malignant neoplasms simultaneously: an amelanotic malignant melanoma metastasizing into a localized renal cell carcinoma.
  • This is the third reported case of a malignant melanoma as donor tumor spreading into a renal cell carcinoma.
  • The amelanotic character of the melanoma exerted a special diagnostic challenge.
  • Clinical and autopsy findings as well as the immunophenotypical features of the metastatic amelanotic melanoma (HMB-45, Melan-A/MART-1, S100) and the renal cell carcinoma are described with a review of the relevant literature.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Melanoma, Amelanotic / pathology

  • Genetic Alliance. consumer health - Kidney cancer.
  • Genetic Alliance. consumer health - Renal cell carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Georg Thieme Verlag KG Stuttgart, New York.
  • (PMID = 20221965.001).
  • [ISSN] 1439-4413
  • [Journal-full-title] Deutsche medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Dtsch. Med. Wochenschr.
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


16. Wu CY, Gao HW, Chiang CP: Malignant amelanotic melanoma developing from an intradermal naevus in a patient with oculocutaneous albinism. Clin Exp Dermatol; 2009 Dec;34(8):e590-3
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant amelanotic melanoma developing from an intradermal naevus in a patient with oculocutaneous albinism.
  • Histopathologically, the tumour revealed benign naevus cells in the upper dermis and atypical malignant tumour cells in the deeper dermis.
  • Amelanotic malignant melanoma (MM) originating from a pre-existing intradermal naevus was diagnosed.
  • [MeSH-major] Albinism, Oculocutaneous / pathology. Melanoma / pathology. Nevus, Intradermal / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Albinism.
  • Genetic Alliance. consumer health - Oculocutaneous Albinism.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19486065.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


17. Kurotaki T, Tomonari Y, Kanno T, Wako Y, Tsuchitani M: Malignant amelanotic melanoma behind the left eye in a female Crj:CD(SD)IGS rat: a case report. Vet Pathol; 2008 Sep;45(5):681-4
MedlinePlus Health Information. consumer health - Eye Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant amelanotic melanoma behind the left eye in a female Crj:CD(SD)IGS rat: a case report.
  • It consisted of various tumor cells; namely, spindle-shaped, epithelioid, anaplastic melanoma cells, and had prominent eosinophilic cytoplasm and nuclei with a greater variation in size.
  • This is the first report describing an amelanotic melanoma in the head of an albino rat.
  • [MeSH-major] Bone Neoplasms / veterinary. Eye Neoplasms / veterinary. Melanoma, Amelanotic / veterinary. Rodent Diseases / pathology

  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18725473.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


18. McGregor DH, Cherian R, Romanas MM, Ulusarac O, Mathur SC, Feldman MM: Amelanotic malignant melanoma: two collision tumors presenting as basal cell carcinoma and atypical fibroxanthoma. Ann Clin Lab Sci; 2008;38(2):157-62
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma: two collision tumors presenting as basal cell carcinoma and atypical fibroxanthoma.
  • We report 2 cases of collision tumors involving amelanotic malignant melanoma of the back.
  • Subsequent excision showed that the lesion was largely composed of amelanotic melanoma underlying a relatively small and thin basal cell carcinoma, and this probably would have been demonstrated in a punch (rather than shave) biopsy.
  • The other patient is a 71-yr-old male with a 1 cm exophytic lesion on the back, which was determined microscopically to be melanoma, and a 0.6 cm papule on the back.
  • This lesion was composed of 2 distinct contiguous neoplastic infiltrates, the predominant component being an atypical fibroxanthoma and the smaller component an amelanotic melanoma (primary vs metastatic), with diagnostic confirmation requiring multiple immunohistochemical stains.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Melanoma, Amelanotic / diagnosis. Neoplasms, Multiple Primary / diagnosis. Skin Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18469362.001).
  • [ISSN] 1550-8080
  • [Journal-full-title] Annals of clinical and laboratory science
  • [ISO-abbreviation] Ann. Clin. Lab. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor
  •  go-up   go-down


19. Grenader T, Isacson R, Reinus C, Rosengarten O, Barenholz O, Hyman J, Gabizon A, Beller U: Primary amelanotic melanoma of the vagina. Onkologie; 2008 Sep;31(8-9):474-6
MedlinePlus Health Information. consumer health - Vaginal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic melanoma of the vagina.
  • BACKGROUND: Primary malignant melanoma of the vagina is extremely rare, accounting for 0.3-0.8% of all malignant melanomas.
  • True amelanotic vaginal melanoma showing no melanin on histological examination is exceedingly rare, accounting for only 2% of all vaginal melanomas.
  • CASE REPORT: We describe a 31-year-old female patient who presented with locally advanced amelanotic melanoma of the vagina, with no evidence of metastatic spread on the computerized tomography (CT) scan, but who was subsequently diagnosed as suffering from metastatic disease by positron emission tomography (PET)-CT performed a few weeks following posterior pelvic exenteration.
  • CONCLUSION: Specific immunohistochemical staining with melanoma markers should be performed to confirm or exclude a diagnosis of amelanotic melanoma in all patients presenting with a vaginal mass composed of undifferentiated epithelioid malignant cells.
  • Fluorodeoxyglucose (FDG)-PET-CT should be performed as part of the preoperative evaluation, to identify the presence or absence of metastatic disease in all patients with vaginal melanoma.
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / surgery. Vaginal Neoplasms / diagnosis. Vaginal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18787356.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


20. Stringa O, Valdez R, Beguerie JR, Abbruzzese M, Lioni M, Nadales A, Iudica F, Venditti J, San Roman A: Primary amelanotic melanoma of the esophagus. Int J Dermatol; 2006 Oct;45(10):1207-10
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic melanoma of the esophagus.
  • Primary melanoma of the esophagus (PME) is an uncommon malignancy with less than 250 cases reported in the literature.
  • Amelanotic PME is exceedingly rare and accounts for 10-25% of melanomas of the esophagus.
  • No skin or eye melanoma lesions were found.
  • Peritumoral lymph nodes revealed malignant invasion.
  • A diagnosis of primary amelanotic melanoma of the esophagus was made.
  • [MeSH-major] Esophageal Neoplasms / pathology. Melanoma, Amelanotic / pathology

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for amelanotic melanoma .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17040443.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
  •  go-up   go-down


21. Harasymowycz P, Boucher MC, Corriveau C, Gauthier D, Allaire G: Choroidal amelanotic melanoma in a patient with oculocutaneous albinism. Can J Ophthalmol; 2005 Dec;40(6):754-8
Genetic Alliance. consumer health - Oculocutaneous Albinism.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Choroidal amelanotic melanoma in a patient with oculocutaneous albinism.
  • CASE REPORT: We describe the clinical presentation of a choroidal amelanotic melanoma in a 46-year-old woman with oculocutaneous albinism.
  • Microscopic findings and histopathological features, demonstrating a spindle B-cell melanoma of the choroid, are also reviewed.
  • COMMENTS: Magnetic resonance imaging may be helpful in diagnosing amelanotic melanoma in patients with oculocutaneous albinism.

  • Genetic Alliance. consumer health - Albinism.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16391642.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


22. Yeşil S, Demir T, Akinci B, Pabuccuoglu U, Ilknur T, Saklamaz A: Amelanotic melanoma misdiagnosed as a diabetic foot ulcer. J Diabetes Complications; 2007 Sep-Oct;21(5):335-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic melanoma misdiagnosed as a diabetic foot ulcer.
  • Amelanotic melanoma often leads to delayed clinical diagnosis because of its wide range of clinical appearances and lack of pigmentation.
  • Misdiagnosis of amelanotic melanoma is also common, particularly when it is located at the foot.
  • Further investigation of the patient in our clinic revealed plantar amelanotic melanoma.
  • [MeSH-major] Diabetic Foot / diagnosis. Melanoma, Amelanotic / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Diabetic Foot.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17825759.001).
  • [ISSN] 1056-8727
  • [Journal-full-title] Journal of diabetes and its complications
  • [ISO-abbreviation] J. Diabetes Complicat.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hemoglobin A, Glycosylated
  •  go-up   go-down


23. Camerin M, Magaraggia M, Soncin M, Jori G, Moreno M, Chambrier I, Cook MJ, Russell DA: The in vivo efficacy of phthalocyanine-nanoparticle conjugates for the photodynamic therapy of amelanotic melanoma. Eur J Cancer; 2010 Jul;46(10):1910-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The in vivo efficacy of phthalocyanine-nanoparticle conjugates for the photodynamic therapy of amelanotic melanoma.
  • The efficiency of a Zn(II)-phthalocyanine disulphide (C11Pc), a compound with both phthalocyanine units bearing seven hexyl chains and a sulphur terminated C11 chain, as a photodynamic therapy (PDT) agent was investigated in C57 mice bearing a sub-cutaneously transplanted amelanotic melanoma.
  • Biodistribution studies at selected post-injection times showed that the nanoparticle-associated C11Pc was recovered in significantly larger amounts from all the examined tissues and the serum and yielded a greater selectivity of tumour targeting: thus, the ratio between the amount of phthalocyanine recovered from the amelanotic melanoma and the skin (peritumoural tissue) increased from 2.3 to 5.5 from the free to the gold nanoparticle-bound C11Pc at 24 h after injection.
  • PDT studies with the C11Pc-loaded amelanotic melanoma showed a markedly more significant response of the tumour in the mice that had received the nanoparticle-bound photosensitiser; the PDT effect was especially extensive if the irradiation was performed at 3h after C11Pc injection when large phthalocyanine amounts were still present in the serum.
  • [MeSH-major] Indoles / therapeutic use. Melanoma, Amelanotic / drug therapy. Metal Nanoparticles / therapeutic use. Organometallic Compounds / therapeutic use. Photochemotherapy / methods. Photosensitizing Agents / therapeutic use. Skin Neoplasms / drug therapy

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20356732.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / / C22031/A7097
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Indoles; 0 / Organometallic Compounds; 0 / Photosensitizing Agents; 14320-04-8 / Zn(II)-phthalocyanine
  •  go-up   go-down


24. André J, Moulonguet I, Goettmann-Bonvallot S: In situ amelanotic melanoma of the nail unit mimicking lichen planus: report of 3 cases. Arch Dermatol; 2010 Apr;146(4):418-21
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] In situ amelanotic melanoma of the nail unit mimicking lichen planus: report of 3 cases.
  • BACKGROUND: Nail apparatus melanoma is known to be associated with a poor prognosis, mainly because of a delay in diagnosis that is made at an invasive stage.
  • This delay is particularly true in cases involving amelanotic melanoma.
  • To our knowledge, only 1 case of in situ amelanotic melanoma of the nail unit has previously been described.
  • We report 3 cases of in situ amelanotic melanoma with clinical lichenoid features.
  • OBSERVATIONS: We describe 3 cases of in situ amelanotic melanoma of the nail unit.
  • Histologic examination revealed in situ amelanotic melanoma extending from the proximal matrix up to the distal part of the nail bed.
  • CONCLUSIONS: Monodactylic lichenoid nail changes should be added to the more conventional signs of incipient nail melanoma.
  • [MeSH-major] Lichen Planus / diagnosis. Melanoma, Amelanotic / diagnosis. Nail Diseases / diagnosis. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Nail Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20404232.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


25. Tolleson WH, Doss JC, Latendresse J, Warbritton AR, Melchior WB Jr, Chin L, Dubielzig RR, Albert DM: Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice. Arch Ophthalmol; 2005 Aug;123(8):1088-94
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice.
  • OBJECTIVE: To characterize a murine model of spontaneous amelanotic melanoma arising in the uvea of transgenic mice bearing a targeted deletion of the Ink4a/Arf tumor suppressor locus (exons 2 and 3) and expressing human H-ras controlled by the human tyrosinase promoter.
  • RESULTS: Uveal melanomas were locally invasive but confined to the eye, with no evidence of metastasis.
  • The retinal pigment epithelium was intact above small melanomas, and electron microscopy of the tumors failed to show the presence of basement membrane formation or desmosomes.
  • CONCLUSION: Spontaneous uveal malignant melanomas occurring in male Tyr-RAS+ Ink4a/Arf-/- transgenic mice arise within the choroid or ciliary body and share histopathological features characteristic of human uveal melanoma.
  • CLINICAL RELEVANCE: Uveal melanoma research has benefited from xenograft models, but engineered mouse models of spontaneous uveal amelanotic melanoma will undoubtedly further our understanding of the genetic underpinning for this disease.
  • [MeSH-major] Cyclin-Dependent Kinase Inhibitor p16 / genetics. Gene Deletion. Genes, ras / genetics. Melanoma, Amelanotic / pathology. Monophenol Monooxygenase / genetics. Tumor Suppressor Protein p14ARF / genetics. Uveal Neoplasms / pathology
  • [MeSH-minor] Animals. Biomarkers, Tumor / analysis. Disease Models, Animal. Genotype. Male. Mice. Mice, Transgenic

  • COS Scholar Universe. author profiles.
  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16087843.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY 01917; United States / NCI NIH HHS / CA / R01 CA 93947
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cdkn2a protein, mouse; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Tumor Suppressor Protein p14ARF; EC 1.14.18.1 / Monophenol Monooxygenase
  •  go-up   go-down


26. Dubrey S, Grocott-Mason R, Mittal T, Burke M: Massive cardiac invasion by amelanotic melanoma with obstructive clinical features. Postgrad Med J; 2008 Mar;84(989):163-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Massive cardiac invasion by amelanotic melanoma with obstructive clinical features.
  • Reports of malignant melanoma involving the heart usually describe metastatic spread of pigmented (melanotic) forms of this tumour.
  • The case is unusual in relation to the extreme size of this amelanotic melanoma at presentation and the fact that it appears to be a solitary metastasis.
  • [MeSH-major] Cardiac Tamponade / etiology. Heart Neoplasms / secondary. Melanoma, Amelanotic / secondary. Skin Neoplasms

  • MedlinePlus Health Information. consumer health - Pericardial Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18372490.001).
  • [ISSN] 1469-0756
  • [Journal-full-title] Postgraduate medical journal
  • [ISO-abbreviation] Postgrad Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


27. Jacob S, Pye E, Hbahbih M, Messios N, Rajabally YA: Rapidly progressive bilateral ophthalmoplegia and enlarging sellar mass caused by amelanotic melanoma. J Neuroophthalmol; 2006 Mar;26(1):49-50
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rapidly progressive bilateral ophthalmoplegia and enlarging sellar mass caused by amelanotic melanoma.
  • Hypophysectomy disclosed an amelanotic melanoma.
  • There are seven reported cases of melanoma arising primarily in the sella turcica.
  • Two cases of metastatic melanoma to the cavernous sinuses have been reported.
  • Amelanotic melanoma has not been reported as a cause of cavernous sinus syndrome.
  • [MeSH-major] Melanoma, Amelanotic / complications. Ophthalmoplegia / etiology. Pituitary Neoplasms / complications. Sella Turcica / pathology
  • [MeSH-minor] Diagnosis, Differential. Disease Progression. Female. Follow-Up Studies. Humans. Hypophysectomy. Magnetic Resonance Imaging. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16518168.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


28. Cichorek M, Kozłowska K, Bryl E: Mitochondrial transmembrane potential in spontaneous and camptothecin-induced apoptosis of melanotic and amelanotic melanoma cells. Neoplasma; 2007;54(1):29-36

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mitochondrial transmembrane potential in spontaneous and camptothecin-induced apoptosis of melanotic and amelanotic melanoma cells.
  • In this work we tried to estimate the role of mitochondria in the ability of cells of two: melanotic and amelanotic transplantable melanoma lines to undergo spontaneous and camptothecin-induced apoptosis.
  • The results of our investigations showed in both transplantable melanoma cells the features indicating apoptosis: DeltaPsi changes, cytochrome c release and PARP cleavage, but the degree of observed changes depended on the phenotype of melanoma cells examined.
  • After camptothecin treatment the changes were more pronounced in the amelanotic melanoma cells- the more aggressive line.
  • [MeSH-minor] Animals. Antineoplastic Agents, Phytogenic / pharmacology. Blotting, Western. Cricetinae. Cytochromes c / secretion. Cytosol / drug effects. Cytosol / metabolism. Flow Cytometry. Male. Melanoma / metabolism. Melanoma / pathology. Melanoma / physiopathology. Mesocricetus. Poly(ADP-ribose) Polymerases / metabolism. Time Factors. Tumor Cells, Cultured

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17203890.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 9007-43-6 / Cytochromes c; EC 2.4.2.30 / Poly(ADP-ribose) Polymerases; XT3Z54Z28A / Camptothecin
  •  go-up   go-down


29. De Simone P, Gelin M, El Nakadi I: Amelanotic malignant melanoma of the esophagus. Report of a case. Minerva Chir; 2006 Feb;61(1):45-9
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the esophagus. Report of a case.
  • Primary malignant melanomas of the esophagus are rare neoplasms with aggressive behavior and tendency to lymphatic and hematogenous spread.
  • We report on a patient affected with a primary amelanotic melanoma of the esophagus synchronous to a squamous cell carcinoma of the epiglottis and treated by subtotal esophagectomy.
  • Review of patient's medical history and exploration of skin and mucous membranes failed to reveal malignant lesions and definitive diagnosis was primary amelanotic malignant melanoma of the esophagus.
  • The patient died 16 months after surgery of disseminated disease.
  • In conclusion the present case confirms that primary malignant melanomas of the esophagus have a dismal outcome even in cases of early-stage lesions amenable to surgical resection.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Epiglottis. Esophageal Neoplasms / pathology. Laryngeal Neoplasms / pathology. Melanoma / pathology. Neoplasms, Multiple Primary / pathology

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16568022.001).
  • [ISSN] 0026-4733
  • [Journal-full-title] Minerva chirurgica
  • [ISO-abbreviation] Minerva Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


30. Mercadier B, Hu W, Valentin S, Sassolas B: [Amelanotic malignant melanoma: about three cases]. Ann Chir Plast Esthet; 2007 Feb;52(1):68-70
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Amelanotic malignant melanoma: about three cases].
  • [Transliterated title] Mélanome malin achromique : à propos de trois cas.
  • The amelanotic melanoma is a rare type of malignant melanoma.
  • The purpose of this report is to point out this aspect of melanoma, whose diagnostic delay is frequent.
  • We describe one localisation on the penis, rare in this kind of melanoma and two cases of the extremities, more frequent localization of the amelanotic melanoma.
  • The therapeutic issues and recommendation are similar to the classical pigmented malignant melanoma.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17030390.001).
  • [ISSN] 0294-1260
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


31. Donaldson MJ, Lim L, Harper CA, Mackenzie J, G Campbell W: Primary treatment of choroidal amelanotic melanoma with photodynamic therapy. Clin Exp Ophthalmol; 2005 Oct;33(5):548-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary treatment of choroidal amelanotic melanoma with photodynamic therapy.
  • The management of choroidal melanoma involves a delicate balance between preserving vision and preventing metastasis.
  • Transpupillary thermotherapy avoids these side-effects; however, it can also result in visual loss and its effectiveness is limited in amelanotic lesions.
  • Photodynamic therapy with verteporfin has shown promise in animal studies of choroidal melanoma, and has recently been used in the management of lesions that have failed to respond to conventional therapy.
  • The authors report a case of primary treatment of a small choroidal amelanotic melanoma with photodynamic therapy using verteporfin.
  • [MeSH-major] Choroid Neoplasms / drug therapy. Melanoma, Amelanotic / drug therapy. Photochemotherapy. Photosensitizing Agents / therapeutic use. Porphyrins / therapeutic use

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Clin Exp Ophthalmol. 2006 Sep-Oct;34(7):721; author reply 721-2 [16970777.001]
  • (PMID = 16181294.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Porphyrins; 129497-78-5 / verteporfin
  •  go-up   go-down


32. Mesa M, Quesada JL, Piñas J: Metastasis of amelanotic melanoma of unknown origin in the parotid gland. Br J Oral Maxillofac Surg; 2009 Oct;47(7):569-71

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasis of amelanotic melanoma of unknown origin in the parotid gland.
  • We report a rare case of metastasis of an amelanotic melanoma of the parotid gland.
  • To our knowledge this is the first report of a metastasis of an amelanotic melanoma in a parotid lymph node.
  • [MeSH-major] Melanoma, Amelanotic / secondary. Neoplasms, Unknown Primary / pathology. Parotid Neoplasms / secondary
  • [MeSH-minor] Aged. Antigens, Neoplasm / analysis. Biopsy, Fine-Needle. Female. Humans. Lymphatic Metastasis / pathology. Magnetic Resonance Imaging. Melanoma-Specific Antigens. Neoplasm Proteins / analysis. S100 Proteins / analysis. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19167137.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  •  go-up   go-down


33. Loizzo MR, Tundis R, Menichini F, Saab AM, Statti GA, Menichini F: Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells. Cell Prolif; 2008 Dec;41(6):1002-12
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells.
  • Antiproliferative activity was tested on amelanotic melanoma C32 cells and on renal cell adenocarcinoma cells, using the sulphorhodamine B assay.
  • RESULTS: Cupressus sempervirens ssp. pyramidalis leaf oil exerted the highest cytotoxic activity with an IC(50)value of 104.90 microg/mL against C32, followed by activity of P. orientalis and P. asperula on the renal adenocarcinoma cell line (IC(50) of 121.93 and 139.17 microg/mL, respectively). P. orientalis essential oil was also active against amelanotic melanoma with an IC(50) of 330.04 microg/mL.
  • [MeSH-major] Carcinoma, Renal Cell / drug therapy. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / drug therapy. Melanoma, Amelanotic / drug therapy. Melanoma, Amelanotic / pathology. Oils, Volatile / therapeutic use. Skin Neoplasms / drug therapy

  • MedlinePlus Health Information. consumer health - Kidney Cancer.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19040575.001).
  • [ISSN] 1365-2184
  • [Journal-full-title] Cell proliferation
  • [ISO-abbreviation] Cell Prolif.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Oils, Volatile; 0 / Plant Oils; 0 / Terpenes
  •  go-up   go-down


34. Cichorek M, Kozłowska K, Bryl E: The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell. Cancer Biol Ther; 2007 Mar;6(3):346-53
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell.
  • Loss of pigment in hamster amelanotic melanoma line is accompanied by a faster growth rate, higher tumorigenicity and shorter animal survival time.
  • Thus, the malignancy of melanoma increases during the alteration of melanotic (Ma) into amelanotic (Ab) line.
  • As changes in the ability to undergo a spontaneous or induced apoptosis, and the role of caspases in this process during melanoma progression are not well defined, they were investigated in this work.
  • Cytochrome c release into cytosol, and the activation of effector caspases, estimated by PARP degradation clearly showed that during the spontaneous death in the cells from both melanoma lines intrinsic way of apoptosis was activated.
  • Confocal and cytometric flow analyses indicate that camptothecin (CPT) induced apoptosis with caspase activation by the intrinsic way only in the amelanotic melanoma cells, even though cells of the Ma line also underwent CPT-induced apoptosis (the content of TUNEL-positive cells increased).
  • Thus, our results suggest that melanoma progression, associated with a decreased ability to undergo spontaneous apoptosis but an increased susceptibility to CPT-induced apoptosis, relates to different levels of caspase activation; they also show that intrinsic way of apoptotis depends on the phenotype of melanoma cells, being more pronounced in the melanotic melanoma cells.
  • On the other hand, melanotic melanoma cells resistance to camptothecin-induced apoptosis suggests that the melanogenic apparatus or melanin itself may have the protective effect on the ability of the melanoma cells to undergo apoptosis.
  • [MeSH-major] Apoptosis. Caspases / metabolism. Melanoma, Amelanotic / enzymology. Melanoma, Experimental / enzymology. Skin Neoplasms / enzymology
  • [MeSH-minor] Animals. Antineoplastic Agents / toxicity. Camptothecin / toxicity. Cell Line, Tumor. Cricetinae. Cytochromes c / metabolism. Disease Progression. Flow Cytometry. Male. Melanins / metabolism. Mesocricetus. Microscopy, Confocal. Poly(ADP-ribose) Polymerases / metabolism

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17312383.001).
  • [ISSN] 1538-4047
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Melanins; 9007-43-6 / Cytochromes c; EC 2.4.2.30 / Poly(ADP-ribose) Polymerases; EC 3.4.22.- / Caspases; XT3Z54Z28A / Camptothecin
  •  go-up   go-down


35. Blum A, Metzler G, Bauer J: Polymorphous vascular patterns in dermoscopy as a sign of malignant skin tumors. A case of an amelanotic melanoma and a porocarcinoma. Dermatology; 2005;210(1):58-9
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Polymorphous vascular patterns in dermoscopy as a sign of malignant skin tumors. A case of an amelanotic melanoma and a porocarcinoma.
  • BACKGROUND: Using dermoscopy (dermatoscopy, epiluminescence microscopy), malignant skin tumors can be detected earlier and unnecessary excisions of benign tumors can be avoided.
  • OBJECTIVE: Description of the dermoscopic vascular patterns of an amelanotic melanoma and a porocarcinoma.
  • METHODS: Dermoscopy of an amelanotic melanoma and a porocarcinoma at 10-fold magnification.
  • CONCLUSION: A reddish tumor without any pigmented network, globules or streaks but with polymorphous vascular patterns must be considered a malignant melanocytic or nonmelanocytic skin tumor.
  • [MeSH-major] Melanoma / diagnosis. Skin Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15604548.001).
  • [ISSN] 1018-8665
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


36. Siddaraju N, Yaranal PJ, Mishra MM, Soundararaghavan J: Fine needle aspiration cytology in recurrent amelanotic melanoma: a case report. Acta Cytol; 2007 Sep-Oct;51(5):829-32
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration cytology in recurrent amelanotic melanoma: a case report.
  • BACKGROUND: Amelanotic melanoma can mimic a wide variety of epithelial and nonepithelial malignant tumors.
  • Varied cytomorphology of melanoma has been described on exfoliative and fine needle aspiration cytology (FNAC).
  • We report a case of recurrent amelanotic melanoma to highlight its varied cytomorphologic features, which may cause diagnostic problems on cytologic and on histologic examinations.
  • FNAC revealed malignant cells with highly varied morphology with plasmacytoid and pleomorphic malignant cells with occasional fibrocollagenous tissue strands showing adherent neoplastic cells.
  • A cytologic diagnosis of pleomorphic malignant tumor was suggested, and the original histologic slides were reviewed; they showed a striking alveolar pattern that vaguely resembled an alveolar rhabdomyosarcoma.
  • A final diagnosis of amelanotic melanoma was made.
  • CONCLUSION: Awareness of the highly varied cytomorphology of amelanotic melanoma minimizes the diagnostic difficulty on fine needle aspiration smears.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Neoplasm Recurrence, Local / pathology. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17910357.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


37. Fusasaki T, Narita R, Hiura M, Abe S, Tabaru A, Hino R, Matsuyama A, Shimajiri S, Tokura Y, Sasaguri Y, Harada M: Acute hepatic failure secondary to extensive hepatic replacement by metastatic amelanotic melanoma: an autopsy case report. Clin J Gastroenterol; 2010 Dec;3(6):327-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acute hepatic failure secondary to extensive hepatic replacement by metastatic amelanotic melanoma: an autopsy case report.
  • Metastatic malignant melanoma (MM) of the liver evolving into acute hepatic failure is a rare occurrence.
  • A liver biopsy revealed amelanotic melanoma cells diffusely infiltrating the hepatic parenchyma.
  • Autopsy revealed >70% infiltration by metastatic amelanotic melanoma in the liver.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 26190491.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Acute hepatic failure / Amelanotic melanoma / Liver metastasis
  •  go-up   go-down


38. Cemil B, Emmez H, Oztanir N, Tokgoz N, Dogulu F: A cystic amelanotic melanoma metastasis to the brain: case report. Neurocirugia (Astur); 2008 Aug;19(4):365-7
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A cystic amelanotic melanoma metastasis to the brain: case report.
  • As far as we know, cyst formation in intracranial melanoma is rare, and only 15 cases of intracranial amelanotic melanoma have been reported until now.
  • The imaging features of metastatic melanomas are distinctive due to the presence of melanin and the propensity for hemorrhage.
  • [MeSH-major] Brain Neoplasms / secondary. Cysts / pathology. Melanoma, Amelanotic / secondary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18726049.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


39. Cichorek M, Kozłowska K, Wachulska M, Zielińska K: Spontaneous apoptosis of melanotic and amelanotic melanoma cells in different phases of cell cycle: relation to tumor growth. Folia Histochem Cytobiol; 2006;44(1):31-6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous apoptosis of melanotic and amelanotic melanoma cells in different phases of cell cycle: relation to tumor growth.
  • Since the spontaneous alteration of native melanotic (Ma) into amelanotic (Ab) transplantable melanoma line it has been observed that this alteration is accompanied by the acceleration of growth of Ab line.
  • Apoptosis estimated by the TUNEL method, alterations in the plasma membrane structure (annexin V staining), changes in the mitochondrial transmembrane potential--delta psi m (JC-1 staining) showed that amelanotic melanoma cells have decreased ability to undergo spontaneous apoptosis.
  • The obtained results showing that in the native melanotic line about 30% of cells are in S+G2/M phases and that 33% of these cells undergo apoptosis could lead to the conclusion that the slower growth of this melanoma line is the result of lower proliferation activity and higher rate of apoptosis of these tumor cells.
  • The number of cells in S+G2/M phases in amelanotic melanoma line increases up to 40% and only 7% of them undergo apoptosis.
  • This observation seems to suggest that the expansive growth of this melanoma line depends mainly on the decreased ability to undergo spontaneous apoptosis, especially in case of cells from S+G2/M phases.
  • Moreover, the obtained results indicate that alteration of melanotic line into amelanotic one, accompanied by differences in many biological features also concerns basic cell processes such as cell cycle and cell death.

  • MedlinePlus Health Information. consumer health - Melanoma.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16584089.001).
  • [ISSN] 0239-8508
  • [Journal-full-title] Folia histochemica et cytobiologica
  • [ISO-abbreviation] Folia Histochem. Cytobiol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Annexin A5; 0 / Phosphatidylserines
  •  go-up   go-down


40. Zerfas PM, Brinster LR, Starost MF, Burkholder TH, Raffeld M, Eckhaus MA: Amelanotic melanoma in a New Zealand White Rabbit (Oryctolagus cuniculus). Vet Pathol; 2010 Sep;47(5):977-81
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic melanoma in a New Zealand White Rabbit (Oryctolagus cuniculus).
  • Positive staining with MART-1 (a melanocyte protein marker) combined with transmission electron microscopy revealing type II melanosomes confirmed the diagnosis of an amelanotic melanoma.
  • [MeSH-major] Facial Neoplasms / veterinary. Lymphatic Metastasis / pathology. Melanoma, Amelanotic / veterinary. Neoplasm Recurrence, Local / veterinary. Rabbits

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20460451.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  •  go-up   go-down


41. Cahill S, Cryer JR, Otter SJ, Ramesar K: An amelanotic malignant melanoma masquerading as hypergranulation tissue. Foot Ankle Surg; 2009;15(3):158-60
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An amelanotic malignant melanoma masquerading as hypergranulation tissue.
  • We report a case of amelanotic malignant melanoma occurring in the nail sulcus of the hallux, which on initial presentation was mistaken for hypergranulation tissue due to an in-growing toenail.
  • [MeSH-major] Melanoma / physiopathology. Melanoma / surgery. Skin Neoplasms / physiopathology. Skin Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19635427.001).
  • [ISSN] 1460-9584
  • [Journal-full-title] Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons
  • [ISO-abbreviation] Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  •  go-up   go-down


42. Latendresse JR, Muskhelishvili L, Warbritton A, Tolleson WH: Two cases of uveal amelanotic melanoma in transgenic Tyr-HRAS+ Ink4a/Arf heterozygous mice. Toxicol Pathol; 2007 Oct;35(6):827-32
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Two cases of uveal amelanotic melanoma in transgenic Tyr-HRAS+ Ink4a/Arf heterozygous mice.
  • Uveal melanoma (UM) is uncommon among wild type mice.
  • Efforts to develop transgenic mice to study this disease have resulted in pigmented tumors derived from the retinal pigment epithelium (RPE) or mixed tumors of RPE and UM complicating the study of UM specifically.
  • Reported here are two early stage intraocular amelanotic melanomas discovered in 2 Tyr-HRAS+ Ink4a/Arf heterozygous (1 normal CKDN2A allele) transgenic FVB/n mice.
  • [MeSH-major] Cyclin-Dependent Kinase Inhibitor p16 / genetics. Disease Models, Animal. Genes, ras. Melanoma, Amelanotic / pathology. Monophenol Monooxygenase / genetics. Uveal Neoplasms / pathology

  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17987514.001).
  • [ISSN] 0192-6233
  • [Journal-full-title] Toxicologic pathology
  • [ISO-abbreviation] Toxicol Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cdkn2a protein, mouse; 0 / Cyclin-Dependent Kinase Inhibitor p16; EC 1.14.18.1 / Monophenol Monooxygenase
  •  go-up   go-down


43. Ikeda K, Tate G, Iezumi K, Suzuki T, Kitamura T, Mitsuya T: Effusion cytomorphology and immunocytochemistry of malignant melanoma: five cases of melanotic melanoma and one case of amelanotic melanoma. Diagn Cytopathol; 2009 Jul;37(7):516-21

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effusion cytomorphology and immunocytochemistry of malignant melanoma: five cases of melanotic melanoma and one case of amelanotic melanoma.
  • Effusion cytological analyses of amelanotic malignant melanoma (AMM) are very rare and no concise description of AMM related cytomorphologic features using effusion have been reported.
  • Here, we report the cytomorphological, immunohistochemical, and immunocytochemical findings in the effusion cytology of six cases of malignant melanoma (MM), one case of AMM, and five cases of melanotic malignant melanoma.
  • With regard to the immunohistochemistry findings, all six cases of melanoma were positive for Melan-A/MART-1, HBME-1, and S-100.
  • In the immunohistochemistry analyses, five of six cases of melanoma were positive for WT-1, as was the AMM specimen.
  • Furthermore, because the effusion analysis of malignant mesothelioma proved positive for WT-1, it should be noted that WT-1 effusion analysis is not an appropriate means to distinguish between MM and malignant mesothelioma.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / metabolism. Neoplasm Proteins / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 19301358.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
  •  go-up   go-down


44. Godbole D, Mojamdar M, Pal JK: Increased level of p27 subunit of proteasomes and its co-localization with tyrosinase in amelanotic melanoma cells indicate its direct role in the regulation of melanin biosynthesis. Cell Biol Int; 2006 Nov;30(11):895-902
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Increased level of p27 subunit of proteasomes and its co-localization with tyrosinase in amelanotic melanoma cells indicate its direct role in the regulation of melanin biosynthesis.
  • Proteasomes have been shown to be involved in the regulation of melanin biosynthesis in melanoma cells.
  • Here we report on the correlation between proteasome subunits and Tyrosinase (Tyr) activity in different cell phenotypes, and thereby regulation of melanin biosynthesis in B16F10 mouse melanoma cells.
  • Our results indicated that the quantity of proteasome subunit p27 is higher and that of the enzyme Tyr and its activity are lower in amelanotic melanoma cells, while the reverse is true in melanotic melanoma cells.
  • Proteasome subunit p27, compared to another subunit p31, shows increased co-localization with Tyr and Tyrosinase related protein 1 (Trp1) in amelanotic cells to a greater extent than that in melanotic cells.
  • On exposure to cycloheximide, increased Tyr degradation was seen in amelanotic cells, as indicated by increased co-localization of p27 and Tyr.
  • Further, exposure of amelanotic melanoma cells with proteasome-specific inhibitor MG132 resulted in an increased Tyr activity, increased levels of Tyr and Trp1, leading to increased melanin synthesis.
  • These results therefore suggest that proteasomes, particularly p27 subunit, are directly involved in the regulation of melanin biosynthesis in mouse melanoma cells.
  • [MeSH-major] Melanins / biosynthesis. Melanoma, Amelanotic / enzymology. Melanoma, Amelanotic / pathology. Monophenol Monooxygenase / metabolism. Proteasome Endopeptidase Complex / metabolism. Protein Subunits / metabolism

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CYCLOHEXIMIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16879986.001).
  • [ISSN] 1065-6995
  • [Journal-full-title] Cell biology international
  • [ISO-abbreviation] Cell Biol. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Leupeptins; 0 / Melanins; 0 / Proteasome Inhibitors; 0 / Protein Subunits; 133407-82-6 / benzyloxycarbonylleucyl-leucyl-leucine aldehyde; 98600C0908 / Cycloheximide; EC 1.- / Oxidoreductases; EC 1.14.18.- / tyrosinase-related protein-1; EC 1.14.18.1 / Monophenol Monooxygenase; EC 3.4.25.1 / Proteasome Endopeptidase Complex
  •  go-up   go-down


45. Roy S, Dhingra K, Mandal S, Khurana N: Unusual presentation of metastatic amelanotic melanoma of unknown primary origin as a solitary breast lump. Melanoma Res; 2008 Dec;18(6):447-50
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual presentation of metastatic amelanotic melanoma of unknown primary origin as a solitary breast lump.
  • Breast is an uncommon site for metastasis from other malignancies especially melanomas.
  • Immunoreactivity for S-100 and HMB-45, confirmed the diagnosis of amelanotic melanoma.
  • It is important to be aware of this atypical presentation of amelanotic melanoma in the breast and to utilize immunohistochemistry to differentiate from other commoner high-grade malignant tumors.
  • [MeSH-major] Breast Neoplasms / secondary. Melanoma, Amelanotic / secondary. Neoplasms, Unknown Primary / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Adult. Antigens, Neoplasm / metabolism. Female. Humans. Melanoma-Specific Antigens. Neoplasm Proteins / metabolism. S100 Proteins / metabolism

  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18971788.001).
  • [ISSN] 1473-5636
  • [Journal-full-title] Melanoma research
  • [ISO-abbreviation] Melanoma Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  •  go-up   go-down


46. Nejc D, Piekarski J, Pasz-Walczak G, Wroński K, Pluta P, Jeziorski A: The first description of sentinel node biopsy in a patient with amelanotic melanoma of the glans penis. Melanoma Res; 2005 Dec;15(6):565-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The first description of sentinel node biopsy in a patient with amelanotic melanoma of the glans penis.
  • We present the first description of sentinel node biopsy in a patient with amelanotic melanoma of the glans penis.
  • Pathologic examination of the postoperative specimen revealed the presence of a very rare malignancy--amelanotic melanoma.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Penile Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16314746.001).
  • [ISSN] 0960-8931
  • [Journal-full-title] Melanoma research
  • [ISO-abbreviation] Melanoma Res.
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


47. Harrison TM, Dominguez P, Hanzlik K, Sikarskie JG, Agnew D, Bergin I, Fitzgerald SD, Kitchell BE, McNiel E: Treatment of an amelanotic melanoma using radiation therapy in a lesser Madagascar hedgehog tenrec (Echinops telfairi). J Zoo Wildl Med; 2010 Mar;41(1):152-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of an amelanotic melanoma using radiation therapy in a lesser Madagascar hedgehog tenrec (Echinops telfairi).
  • Immunohistochemically, the original, recurrent, and metastatic populations were strongly positive for HMB 45 and weakly positive for S-100, and the final diagnosis was metastatic amelanotic melanoma.
  • [MeSH-major] Insectivora. Melanoma, Amelanotic / veterinary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20722271.001).
  • [ISSN] 1042-7260
  • [Journal-full-title] Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians
  • [ISO-abbreviation] J. Zoo Wildl. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


48. Nakamoto T, Inoue Y, Ueki T, Niimi N, Iwasaki Y: Primary amelanotic malignant melanoma of the female urethra. Int J Urol; 2007 Feb;14(2):153-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic malignant melanoma of the female urethra.
  • The case is reported of amelanotic malignant melanoma of the female urethra mimicking urethral caruncle.
  • Urethral carunclectomy was performed, but histological diagnosis was amelanotic malignant melanoma.
  • [MeSH-major] Melanoma, Amelanotic. Urethral Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17302574.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


49. Matusiak L, Bieniek A, Wozniak Z, Szepietowski JC: Amelanotic malignant melanoma in an acral location. Acta Dermatovenerol Alp Pannonica Adriat; 2008 Jun;17(2):72-4
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma in an acral location.
  • The biopsy, stained with H and E, revealed an anaplastic malignant tumor.
  • Additional immunochemical staining with Melan A allowed us to make the final diagnosis: amelanotic malignant melanoma (MM).
  • The melanoma was removed by amputation of digits IV and V, with partial removal of the metatarsal bones (Clark degree 5, Breslow thickness 9 mm).
  • [MeSH-major] Foot Dermatoses / pathology. Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18709293.001).
  • [ISSN] 1318-4458
  • [Journal-full-title] Acta dermatovenerologica Alpina, Pannonica, et Adriatica
  • [ISO-abbreviation] Acta Dermatovenerol Alp Pannonica Adriat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Slovenia
  •  go-up   go-down


50. Yoshii T, Horiguchi A, Shirotake S, Tobe M, Tasaki S, Hayakawa M, Sumitomo M, Asano T: [Case of primary amelanotic malignant melanoma of the female urethra]. Nihon Hinyokika Gakkai Zasshi; 2010 Sep;101(6):734-7
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Case of primary amelanotic malignant melanoma of the female urethra].
  • We report a rare case of primary amelanotic malignant melanoma of the female urethra.
  • Pathological diagnosis of the biopsy specimen from the nodule was malignant melanoma.
  • The histopathological diagnosis was amelanotic malignant melanoma of the urethra.
  • [MeSH-major] Melanoma, Amelanotic / surgery. Urethra / surgery. Urethral Neoplasms / surgery

  • Hazardous Substances Data Bank. DACARBAZINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20954381.001).
  • [ISSN] 0021-5287
  • [Journal-full-title] Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
  • [ISO-abbreviation] Nippon Hinyokika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0S726V972K / Nimustine; 5J49Q6B70F / Vincristine; 77238-31-4 / Interferon-beta; 7GR28W0FJI / Dacarbazine; DAV protocol
  •  go-up   go-down


51. Gao N, Li LJ, Li Y, Wang L: Primary amelanotic malignant melanoma of the parotid gland: a case report. J Int Med Res; 2008 Nov-Dec;36(6):1435-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic malignant melanoma of the parotid gland: a case report.
  • Amelanotic malignant melanoma in the oral region is extremely rare and has not previously been reported in the parotid gland.
  • This present case report describes an amelanotic malignant melanoma in the parotid gland, with no other primary lesion detectable.
  • Amelanotic malignant melanoma is a melanoma subtype with little or no pigmentation and, because of this lack of pigmentation and its wide-ranging clinical appearance, it often defies clinical diagnosis.
  • Where it is suspected, positive expression of S-100 protein and human melanoma black 45(HMB45) using immunohistochemical analysis can be considered reliable methods of confirming diagnosis.
  • [MeSH-major] Melanoma, Amelanotic / secondary. Parotid Gland / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Fatal Outcome. Humans. Lymph Nodes / pathology. Male. Melanoma-Specific Antigens. Neoplasm Proteins / analysis. S100 Proteins / analysis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19094455.001).
  • [ISSN] 0300-0605
  • [Journal-full-title] The Journal of international medical research
  • [ISO-abbreviation] J. Int. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  •  go-up   go-down


52. Kato H, Inoue Y, Ishihara T, Kageshita T, Ihn H: Amelanotic malignant melanoma where primary lesion was discovered 5 years after metastasis in the lymph node. J Dermatol; 2010 Aug;37(8):730-4
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma where primary lesion was discovered 5 years after metastasis in the lymph node.
  • He was diagnosed as having a malignant tumor of the soft tissues at a local hospital; however, an exact diagnosis was not obtained.
  • He was diagnosed as having amelanotic malignant melanoma and the lesion was resected.
  • In our hospital, we have experienced 16 cases of amelanotic malignant melanoma.
  • Generally, it is reported that the patients with amelanotic malignant melanoma have a poor prognosis, but we have observed no difference in the outcome between the patients with amelanotic malignant melanoma and those with malignant melanoma.
  • [MeSH-major] Foot Diseases / pathology. Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Foot Injuries and Disorders.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. DACARBAZINE .
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20649717.001).
  • [ISSN] 1346-8138
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; CYVADIC protocol
  •  go-up   go-down


53. Di Domenico F, Foppoli C, Blarzino C, Perluigi M, Paolini F, Morici S, Coccia R, Cini C, De Marco F: Expression of human papilloma virus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity. J Exp Clin Cancer Res; 2009;28:4
Hazardous Substances Data Bank. DOPAMINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of human papilloma virus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity.
  • In tyrosinase-positive amelanotic melanomas this rate limiting enzyme is inactive because of acidic endo-melanosomal pH.
  • METHODS: The expression of the HPV16-E5 oncoproteins was induced in two Tyrosinase-positive amelanotic melanomas (the cell lines FRM and M14) by a retroviral expression construct.
  • In amelanotic melanomas these effects can modulate the cell phenotype and can induce a higher sensitivity to tyrosine related anti-blastic drugs.
  • [MeSH-major] Melanoma, Amelanotic / metabolism. Monophenol Monooxygenase / metabolism. Oncogene Proteins, Viral / metabolism. Skin Neoplasms / metabolism

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • Cellosaurus - a cell line knowledge resource. culture/stock collections - FRM (CVCL_M212) .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Exp Biol. 2000 Jan;203(Pt 1):61-70 [10600674.001]
  • [Cites] Oncogene. 2000 Aug 3;19(33):3727-32 [10949926.001]
  • [Cites] Br J Cancer. 2000 Jul;83(2):184-7 [10901368.001]
  • [Cites] FEBS Lett. 2000 Jul 28;478(1-2):57-60 [10922469.001]
  • [Cites] Exp Cell Res. 2001 Jan 15;262(2):197-208 [11139343.001]
  • [Cites] Oncogene. 2000 Dec 7;19(52):6023-32 [11146554.001]
  • [Cites] Exp Cell Res. 2001 Aug 1;268(1):26-35 [11461115.001]
  • [Cites] J Gen Virol. 2001 Oct;82(Pt 10):2353-62 [11562529.001]
  • [Cites] Oncogene. 2001 Nov 26;20(54):7866-73 [11753669.001]
  • [Cites] Oncogene. 2002 Jan 10;21(2):248-59 [11803468.001]
  • [Cites] Nat Rev Cancer. 2002 May;2(5):342-50 [12044010.001]
  • [Cites] Oncol Res. 2002;13(1):3-8 [12201672.001]
  • [Cites] Biochem Pharmacol. 2002 Nov 15;64(10):1503-12 [12417263.001]
  • [Cites] Cancer Res. 2003 Jan 15;63(2):441-8 [12543800.001]
  • [Cites] Virology. 2003 May 25;310(1):100-8 [12788634.001]
  • [Cites] J Biol Chem. 2004 Feb 27;279(9):7971-81 [14634018.001]
  • [Cites] Cell. 1983 May;33(1):153-9 [6678608.001]
  • [Cites] J Immunol Methods. 1986 Nov 20;94(1-2):57-63 [3782817.001]
  • [Cites] Proc Natl Acad Sci U S A. 1988 Nov;85(21):7972-6 [2973058.001]
  • [Cites] J Virol. 1989 Oct;63(10):4417-21 [2476573.001]
  • [Cites] J Virol. 1990 Jul;64(7):3226-33 [2161939.001]
  • [Cites] Pigment Cell Res. 1990 Mar-Apr;3(2):49-54 [2117268.001]
  • [Cites] Anal Biochem. 1991 Feb 1;192(2):316-21 [1827963.001]
  • [Cites] J Biol Regul Homeost Agents. 1991 Apr-Jun;5(2):65-70 [1716817.001]
  • [Cites] J Virol. 1991 Dec;65(12):7078-83 [1658398.001]
  • [Cites] Biochemistry. 1993 Apr 20;32(15):3902-6 [8385991.001]
  • [Cites] J Invest Dermatol. 1993 Jun;100(6):806-11 [8496620.001]
  • [Cites] J Virol. 1993 Aug;67(8):4521-32 [8392596.001]
  • [Cites] J Virol. 1993 Oct;67(10):6170-8 [7690419.001]
  • [Cites] Virology. 1994 Aug 15;203(1):73-80 [8030286.001]
  • [Cites] J Virol. 1995 May;69(5):3185-92 [7707548.001]
  • [Cites] J Gen Virol. 1995 May;76 ( Pt 5):1239-45 [7730808.001]
  • [Cites] J Virol. 1995 Dec;69(12):8051-6 [7494320.001]
  • [Cites] Biochim Biophys Acta. 1996 Oct 9;1288(2):F55-78 [8876633.001]
  • [Cites] Cancer Res. 1998 Apr 1;58(7):1521-3 [9537258.001]
  • [Cites] Exp Cell Res. 1998 May 25;241(1):76-83 [9633515.001]
  • [Cites] Int J Cancer. 2005 Jan 10;113(2):276-83 [15386416.001]
  • [Cites] J Virol. 2004 Dec;78(24):13613-26 [15564472.001]
  • [Cites] Arch Virol. 2005 Feb;150(2):231-46 [15503216.001]
  • [Cites] Virology. 2005 Feb 5;332(1):102-13 [15661144.001]
  • [Cites] Int J Biochem Cell Biol. 2005 Apr;37(4):852-63 [15694844.001]
  • [Cites] Virology. 2005 Jun 20;337(1):76-84 [15914222.001]
  • [Cites] Neoplasia. 2006 Jul;8(7):543-50 [16867216.001]
  • [Cites] Oncogene. 2008 Feb 14;27(8):1071-8 [17704805.001]
  • [Cites] Virol J. 2008;5:30 [18302753.001]
  • [Cites] Oncogene. 2008 Apr 17;27(18):2532-41 [17982485.001]
  • [Cites] Virology. 2000 Jul 5;272(2):315-25 [10873774.001]
  • (PMID = 19133143.001).
  • [ISSN] 1756-9966
  • [Journal-full-title] Journal of experimental & clinical cancer research : CR
  • [ISO-abbreviation] J. Exp. Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Melanins; 0 / Oncogene Proteins, Viral; 0 / Proton Pump Inhibitors; 0 / RNA, Messenger; 0 / oncogene protein E5, Human papillomavirus type 16; 37491-68-2 / 3,4-dihydroxybenzylamine; 5072-26-4 / Buthionine Sulfoximine; EC 1.14.18.1 / Monophenol Monooxygenase; VTD58H1Z2X / Dopamine
  • [Other-IDs] NLM/ PMC2654431
  •  go-up   go-down


54. Ishii H, Joshita T, Matsuyama N, Uchida T, Ishikawa A, Ebihara Y: Immunohistochemical and ultrastructural investigation on cutaneous neuroendocrine carcinoma: report of a case and review of the literature. Med Mol Morphol; 2006 Sep;39(3):164-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a tumor in an 80-year-old man that was difficult to distinguish from other tumors, i.e., small cell carcinoma of the lung, PNET/Ewing tumor, malignant lymphoma, or malignant melanoma (amelanotic), and which was finally identified as cutaneous neuroendocrine carcinoma using immunohistochemical and ultrastructural methods.
  • Immunohistochemistry tests gave negative results for LCA, UCHL-1, CD3, and CD20, thereby excluding malignant lymphoma, and the negative results for S-100 protein and HMB-45 ruled out malignant melanoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16998628.001).
  • [ISSN] 1860-1480
  • [Journal-full-title] Medical molecular morphology
  • [ISO-abbreviation] Med Mol Morphol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


55. Liébana ES, González DJ, Martín M, Saiz A: Atypical presentation of cardiac metastasis of amelanotic melanoma. Int J Cardiovasc Imaging; 2009 Apr;25(4):343-4
Hazardous Substances Data Bank. GADOPENTETATE DIMEGLUMINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical presentation of cardiac metastasis of amelanotic melanoma.
  • We present the case of a 67-year-old patient, asymptomatic, with a prior diagnosis of amelanotic cutaneous melanoma with positive ganglions (2002), who was referred for thoracic-abdominal-pelvic computed tomography (CT) as part of routine follow-up (2007).
  • [MeSH-major] Heart Neoplasms / diagnosis. Heart Neoplasms / secondary. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / secondary. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19214775.001).
  • [ISSN] 1875-8312
  • [Journal-full-title] The international journal of cardiovascular imaging
  • [ISO-abbreviation] Int J Cardiovasc Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
  •  go-up   go-down


56. Terada T: Amelanotic malignant melanoma of the esophagus: report of two cases with immunohistochemical and molecular genetic study of KIT and PDGFRA. World J Gastroenterol; 2009 Jun 7;15(21):2679-83
MedlinePlus Health Information. consumer health - Esophageal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the esophagus: report of two cases with immunohistochemical and molecular genetic study of KIT and PDGFRA.
  • The author reports herein two cases of amelanotic malignant melanoma of the esophagus.
  • The biopsy showed malignant polygonal and spindle cells.
  • The biopsy showed malignant spindle cells without melanin pigment.
  • This is the first report of esophageal malignant melanoma with an examination of the expression of KIT and PDGFRA and the mutational status of KIT and PDGFRA genes.
  • [MeSH-major] Esophageal Neoplasms. Melanoma, Amelanotic. Receptor, Platelet-Derived Growth Factor alpha / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Z Gastroenterol. 2005 Jun;43(6):597-600 [15986290.001]
  • [Cites] Hum Pathol. 2005 May;36(5):486-93 [15948115.001]
  • [Cites] Melanoma Res. 2005 Aug;15(4):251-6 [16034302.001]
  • [Cites] Melanoma Res. 2005 Aug;15(4):283-5 [16034306.001]
  • [Cites] Appl Immunohistochem Mol Morphol. 2005 Sep;13(3):205-20 [16082245.001]
  • [Cites] N Engl J Med. 2005 Nov 17;353(20):2135-47 [16291983.001]
  • [Cites] Pathol Int. 2006 Jan;56(1):1-9 [16398673.001]
  • [Cites] Minerva Chir. 2006 Feb;61(1):45-9 [16568022.001]
  • [Cites] J Invest Dermatol. 2006 May;126(5):1102-10 [16410786.001]
  • [Cites] J Clin Oncol. 2006 Sep 10;24(26):4340-6 [16908931.001]
  • [Cites] Int J Dermatol. 2006 Oct;45(10):1207-10 [17040443.001]
  • [Cites] Arch Pathol Lab Med. 2006 Oct;130(10):1466-78 [17090188.001]
  • [Cites] Semin Diagn Pathol. 2006 May;23(2):91-102 [17193822.001]
  • [Cites] J Cutan Pathol. 2007 Jan;34(1):7-14 [17214848.001]
  • [Cites] Melanoma Res. 2007 Aug;17(4):239-42 [17625454.001]
  • [Cites] J Invest Dermatol. 2008 Feb;128(2):488-9 [17762857.001]
  • [Cites] Pathol Int. 2008 Jul;58(7):432-5 [18577112.001]
  • [Cites] Arch Pathol Lab Med. 2008 Oct;132(10):1623-9 [18834221.001]
  • [Cites] Clin Cancer Res. 2008 Nov 1;14(21):6821-8 [18980976.001]
  • [Cites] Pathol Int. 2008 Dec;58(12):801-5 [19067857.001]
  • [Cites] Pathol Int. 2008 Dec;58(12):806-9 [19067858.001]
  • [Cites] World J Gastroenterol. 2008 Dec 21;14(47):7256-9 [19084944.001]
  • [Cites] Int J Gynecol Pathol. 2009 Jan;28(1):29-34 [19047911.001]
  • [Cites] Pathol Int. 2009 Jan;59(1):53-8 [19121093.001]
  • [Cites] Pathol Int. 2009 Apr;59(4):247-50 [19351368.001]
  • [Cites] Med Oncol. 2009;26(2):233-7 [18777214.001]
  • [Cites] Med Oncol. 2009;26(2):247-50 [18989797.001]
  • [Cites] Pathol Int. 2002 Nov;52(11):740-6 [12685552.001]
  • [Cites] Gastroenterology. 2003 Sep;125(3):660-7 [12949711.001]
  • [Cites] Melanoma Res. 2003 Dec;13(6):595-601 [14646623.001]
  • [Cites] Pathol Int. 2004 Feb;54(2):116-23 [14720143.001]
  • [Cites] J Surg Oncol. 1979;12(1):19-25 [113625.001]
  • [Cites] Jpn J Clin Oncol. 1990 Sep;20(3):286-95 [2255105.001]
  • [Cites] Gastroenterol Jpn. 1991 Apr;26(2):209-12 [2040402.001]
  • [Cites] Gut. 1991 Jul;32(7):828-30 [1855693.001]
  • [Cites] Jpn J Clin Oncol. 1991 Aug;21(4):306-13 [1942560.001]
  • [Cites] Mod Pathol. 1997 Sep;10(9):939-44 [9310959.001]
  • [Cites] Science. 1998 Jan 23;279(5350):577-80 [9438854.001]
  • [Cites] Hum Pathol. 1998 May;29(5):498-504 [9596274.001]
  • [Cites] J Clin Oncol. 2005 Jan 1;23(1):49-57 [15545668.001]
  • [Cites] Tohoku J Exp Med. 2005 Jul;206(3):271-5 [15942157.001]
  • [Cites] Int J Clin Oncol. 2005 Jun;10(3):204-7 [15990972.001]
  • (PMID = 19496203.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha
  • [Other-IDs] NLM/ PMC2691504
  •  go-up   go-down


57. Suzuki Y, Aoyama N, Minamide J, Takata K, Ogata T: Amelanotic malignant melanoma of the esophagus: report of a patient with recurrence successfully treated with chemoendocrine therapy. Int J Clin Oncol; 2005 Jun;10(3):204-7
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the esophagus: report of a patient with recurrence successfully treated with chemoendocrine therapy.
  • We report a case of primary amelanotic malignant melanoma of the esophagus, an extremely rare disease.
  • In general, the prognosis of esophageal malignant melanoma is very poor.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Esophageal Neoplasms / drug therapy. Melanoma / drug therapy

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
  • Hazardous Substances Data Bank. DACARBAZINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15990972.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0S726V972K / Nimustine; 5J49Q6B70F / Vincristine; 77238-31-4 / Interferon-beta; 7GR28W0FJI / Dacarbazine; Q20Q21Q62J / Cisplatin
  •  go-up   go-down


58. Pietzner K, Noske A, Cho CH, Kiecker F, Sehouli J: Amelanotic metastasis of melanoma mimicking ovarian cancer: a case report and review of the literature. Anticancer Res; 2008 Jan-Feb;28(1B):563-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic metastasis of melanoma mimicking ovarian cancer: a case report and review of the literature.
  • Ovarian manifestation of metastatic amelanotic melanoma is exceptionally rare and can lead to the clinical and even histological misdiagnosis of ovarian cancer.
  • She was histologically diagnosed with malignant ovarian tumour and was referred for radical surgery.
  • Postoperative final histological examination and immunohistochemical staining of the tumour revealed an amelanotic epithelioid melanoma.
  • This report discusses the differential diagnosis and clinical management of both metastatic amelanotic malignant melanoma of the ovary and epithelial ovarian cancer.
  • [MeSH-major] Melanoma, Amelanotic / secondary. Ovarian Neoplasms / diagnosis. Skin Neoplasms / secondary

  • Genetic Alliance. consumer health - Ovarian cancer.
  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18383903.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


59. Rizvi SA, Amitava AK, Mehdi G, Sharma R, Alam MS: Orbital amelanotic melanoma in xeroderma pigmentosum: a rare association. Indian J Ophthalmol; 2008 Sep-Oct;56(5):421-3
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital amelanotic melanoma in xeroderma pigmentosum: a rare association.
  • Ocular neoplasms occurring in XP in order of frequency are squamous cell carcinoma, basal cell carcinoma and melanoma.
  • Malignant melanomas occur at an early age in patients with XP.
  • We report a case of XP with massive orbital melanoma in an eight-year-old boy which is unique due to its amelanotic presentation confirmed histopathologically.
  • [MeSH-major] Melanoma, Amelanotic / complications. Orbit. Skin Neoplasms / complications. Xeroderma Pigmentosum / complications

  • Genetic Alliance. consumer health - Xeroderma pigmentosum.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Intern Med. 1974 Feb;80(2):221-48 [4811796.001]
  • [Cites] Cancer. 1982 Sep 1;50(5):912-8 [6807528.001]
  • [Cites] Arch Dermatol. 1987 Feb;123(2):241-50 [3545087.001]
  • [Cites] Tunis Med. 2006 Sep;84(9):542-4 [17263199.001]
  • [Cites] Br J Ophthalmol. 1993 Sep;77(9):597-8 [8218060.001]
  • [Cites] Br J Ophthalmol. 1994 Apr;78(4):295-7 [8199117.001]
  • [Cites] Br J Dermatol. 1965 May;77:261-76 [14283428.001]
  • [Cites] Arch Ophthalmol. 1989 Mar;107(3):402-7 [2923565.001]
  • (PMID = 18711275.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2636150
  •  go-up   go-down


60. Duggal R, Srinivasan R: Primary amelanotic melanoma of the cervix: case report with review of literature. J Gynecol Oncol; 2010 Sep;21(3):199-202

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary amelanotic melanoma of the cervix: case report with review of literature.
  • Primary malignant melanoma of the uterine cervix is a rare neoplasm with poor prognosis.
  • It may be misdiagnosed especially when amelanotic, in which case immunohistochemistry is useful in reaching the diagnosis.
  • On histopathological examination it was originally suspected to be a poorly differentiated carcinoma or a non-epithelial malignant tumor, but was subsequently correctly diagnosed by immunohistochemical staining with the HMB-45 antibody and S-100 protein.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20922145.001).
  • [ISSN] 2005-0399
  • [Journal-full-title] Journal of gynecologic oncology
  • [ISO-abbreviation] J Gynecol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2948230
  • [Keywords] NOTNLM ; Aamelanotic melanoma / HMB-45 antibody
  •  go-up   go-down


61. Stroh C, Manger T: [Primary amelanotic anorectal melanoma--a case report]. Zentralbl Chir; 2007 Dec;132(6):560-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary amelanotic anorectal melanoma--a case report].
  • [Transliterated title] Das primäre amelanotische Melanom des Rektums - Ein Fallbericht.
  • BACKGROUND: The amelanotic melanoma of the rectal mucosa is very rare with an unfavourable prognosis.
  • METHODS: In literature 5 cases of amelanotic malignant melanoma were reported.
  • RESULTS: We report about a 55-year-old female patient with an amelanotic melanoma of rectal mucosa.
  • CONCLUSION: The prognosis of primary malignant anorectal melanoma is poor, irrespective of surgical treatment.
  • Wide local resection is the first choice for primary anorectal melanoma.
  • Chemotherapy, radiotherapy and immunotherapy should be considered in the treatment of anorectal melanoma to influence the overall survival.
  • [MeSH-major] Melanoma, Amelanotic / surgery. Rectal Neoplasms / surgery
  • [MeSH-minor] Chemotherapy, Adjuvant. Disease Progression. Endosonography. Fatal Outcome. Female. Follow-Up Studies. Humans. Intestinal Mucosa / pathology. Intestinal Mucosa / surgery. Intestinal Mucosa / ultrasonography. Lymph Node Excision. Middle Aged. Neoplasm Recurrence, Local / drug therapy. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Recurrence, Local / ultrasonography. Neoplasm Staging. Palliative Care. Proctoscopy. Radiotherapy, Adjuvant. Reoperation

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18098086.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


62. Kurotaki T, Tomonari Y, Kanno T, Wako Y, Tsuchitani M: A novel immunohistochemical marker of normal and neoplastic melanocytes in formalin-fixed, paraffin-embedded tissues of albino rats. Vet Pathol; 2008 May;45(3):383-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The samples consisted of 11 (1.57%) amelanotic melanomas in 700 rats (2 studies), 23 non-melanocytic tumors, and a wide variety of normal tissues.
  • In amelanotic melanoma, the tumor cells consisted of spindle cells with eosinophilic cytoplasm without melanin granules.
  • PNL2 consistently stained cytoplasm in all amelanotic melanoma cells.
  • [MeSH-major] Melanocytes / cytology. Melanocytes / pathology. Melanoma / pathology

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18487499.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


63. Camerin M, Rello S, Villanueva A, Ping X, Kenney ME, Rodgers MA, Jori G: Photothermal sensitisation as a novel therapeutic approach for tumours: studies at the cellular and animal level. Eur J Cancer; 2005 May;41(8):1203-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Irradiation of B78H1 murine amelanotic melanoma cells with 850 nm light emitted from a Ti:sapphire laser, operated in a pulsed mode at high fluence rates and in the presence of Ni(II)-octabutoxy-naphthalocyanine (NiNc), promoted a photothermally sensitised process leading to fast and irreversible cell death.
  • Very similar results were obtained upon irradiation of NiNc-loaded C32 human amelanotic melanoma cells and transformed murine HT-1080 and HaCaT fibroblasts.
  • From these results, photothermal sensitisation appears to be a general phenomenon and preliminary studies with mice bearing subcutaneously transplanted amelanotic melanomas, irradiated with 850 nm light 24 h after intravenous injection of NiNc, suggest that this approach has potential for the therapy of some types of skin tumours.
  • [MeSH-major] Melanoma, Amelanotic / drug therapy. Metalloporphyrins / therapeutic use. Photochemotherapy / methods. Photosensitizing Agents / therapeutic use

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15911245.001).
  • [ISSN] 0959-8049
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 91027
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Metalloporphyrins; 0 / Photosensitizing Agents; 0 / octabutoxynaphthalocyaninenickel(II)
  •  go-up   go-down


64. Said A, Tundis R, Hawas UW, El-Kousy SM, Rashed K, Menichini F, Bonesi M, Huefner A, Loizzo MR, Menichinib F: In vitro antioxidant and antiproliferative activities of flavonoids from Ailanthus excelsa (Roxb.) (Simaroubaceae) leaves. Z Naturforsch C; 2010 Mar-Apr;65(3-4):180-6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Compounds 1 and 3 inhibited cell growth in both amelanotic melanoma and malignant melanoma cells.

  • MedlinePlus Health Information. consumer health - Antioxidants.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20469635.001).
  • [ISSN] 0939-5075
  • [Journal-full-title] Zeitschrift für Naturforschung. C, Journal of biosciences
  • [ISO-abbreviation] Z. Naturforsch., C, J. Biosci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Biphenyl Compounds; 0 / Flavonoids; 0 / Free Radical Scavengers; 0 / Picrates; 1898-66-4 / 2,2-diphenyl-1-picrylhydrazyl
  •  go-up   go-down


65. Heidemann J, Lebiedz P, Herbst H, Spahn TW, Domagk D, Domschke W, Kucharzik T: Amelanotic malignant melanoma of the esophagus: case report. Z Gastroenterol; 2005 Jun;43(6):597-600
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the esophagus: case report.
  • We present the case of a primary malignant esophageal melanoma arising in a 75-year-old male, initially diagnosed as anaplastic squamous cell carcinoma.
  • After resection of the tumor, histological work-up was indicative of a marked morphological heterogeneity, resembling a focally amelanotic primary malignant melanoma.
  • Primary malignant melanomas of the esophagus are exceptionally rare.
  • [MeSH-major] Carcinoma, Squamous Cell / radiography. Esophageal Neoplasms / pathology. Esophageal Neoplasms / radiography. Melanoma / pathology. Melanoma / radiography

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15986290.001).
  • [ISSN] 0044-2771
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


66. Mandato VD, Kobal B, Di Stefano A, Sinkovec J, Levicnik A, Rakar S, Costagliola L: Amelanotic malignant melanoma of the uterine cervix with ten-year follow-up. Eur J Gynaecol Oncol; 2009;30(1):106-9
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic malignant melanoma of the uterine cervix with ten-year follow-up.
  • BACKGROUND: Malignant melanoma (MM) accounts for 3% of cancers that affect women and results in less than 1% of cancer deaths.
  • Fewer than ten cases of amelanotic MM (AMM) have been reported in literature.
  • The patient is clinically free of disease ten years postoperatively.
  • CONCLUSION: Malignant melanoma of the cervix is often misdiagnosed because of non discriminatory features and the capacity to mimic other tumors.
  • Malignant melanoma of the cervix needs to be diagnosed as quickly as possible because a timely therapy and a long and careful follow-up might result in better survival.
  • [MeSH-major] Melanoma, Amelanotic / pathology. Skin Neoplasms / pathology. Uterine Cervical Neoplasms / pathology

  • Genetic Alliance. consumer health - TEN.
  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19317272.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


67. Conforti F, Menichini F, Rigano D, Senatore F: Antiproliferative activity on human cancer cell lines after treatment with polyphenolic compounds isolated from Iris pseudopumila flowers and rhizomes. Z Naturforsch C; 2009 Jul-Aug;64(7-8):490-4
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The in vitro cytotoxic activity assay against two human cancer cell lines, large lung carcinoma (CORL-23) and amelanotic melanoma (C32), showed that the most antiproliferative extract was the MeOH extract from flowers with a percentage of inhibition of 50.9 at 100 microg/ml against amelanotic melanoma cells.
  • The most antiproliferative compounds against amelanotic melanoma cells were kaempferol-3-O-beta-D-glucopyranoside and irisolidone with a percentage of inhibition of 100 and 96.6, respectively, and against large lung carcinoma cells with a percentage of inhibition of 82.1 and 84.6, respectively.
  • Significant activity on the amelanotic melanoma cell line was also showed by irigenin-7-O-beta-D-glucopyranoside, with a percentage of inhibition of 89.3.
  • The compounds isovitexin and isoorientin-6-O''-beta-D-glucopyranoside showed a selective activity against amelanotic melanoma cells with a percentage of inhibition of 83.2 and 79.8, respectively.
  • [MeSH-minor] Carcinoma, Large Cell / pathology. Cell Line, Tumor. Humans. Lung Neoplasms / pathology. Melanoma, Amelanotic / pathology. Plant Extracts / chemistry. Polyphenols

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19791498.001).
  • [ISSN] 0939-5075
  • [Journal-full-title] Zeitschrift für Naturforschung. C, Journal of biosciences
  • [ISO-abbreviation] Z. Naturforsch., C, J. Biosci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Flavonoids; 0 / Phenols; 0 / Plant Extracts; 0 / Polyphenols
  •  go-up   go-down


68. Seya T, Tanaka N, Shinji S, Shinji E, Yokoi K, Horiba K, Kanazawa Y, Yamada T, Oaki Y, Tajiri T: Case of rectal malignant melanoma showing immunohistochemical variability in a tumor. J Nippon Med Sch; 2007 Oct;74(5):377-81
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case of rectal malignant melanoma showing immunohistochemical variability in a tumor.
  • We report on a patient with rectal malignant melanoma.
  • However, the final pathological diagnosis of the surgically resected specimen was malignant amelanotic melanoma of the rectum.
  • However, there were no anticancer drugs tested by CD-DST for malignant melanoma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Melanoma / diagnosis. Neoplasm Proteins / analysis. Proto-Oncogene Proteins c-kit / analysis. Rectal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Antigens, Neoplasm. Antineoplastic Combined Chemotherapy Protocols / pharmacology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Digestive System Surgical Procedures. Drug Resistance, Neoplasm. Drug Screening Assays, Antitumor / methods. Fatal Outcome. Humans. Immunohistochemistry. Interferon-beta / administration & dosage. Male. Melanoma-Specific Antigens. Neoadjuvant Therapy. Tumor Cells, Cultured

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17965534.001).
  • [ISSN] 1345-4676
  • [Journal-full-title] Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
  • [ISO-abbreviation] J Nippon Med Sch
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 77238-31-4 / Interferon-beta; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  •  go-up   go-down


69. Baderca F, Cojocaru S, Lazăr E, Lăzureanu C, Lighezan R, Alexa A, Raica M, Nicola T: Amelanotic vulvar melanoma: case report and review of the literature. Rom J Morphol Embryol; 2008;49(2):219-28
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for vulvar melanoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amelanotic vulvar melanoma: case report and review of the literature.
  • A rare case of amelanotic vulvar melanoma is presented.
  • A biopsy was taken and a histopathological suspicion of amelanotic melanoma was rendered.
  • Malignant melanoma is readily diagnosed by the presence of melanin granules.
  • Although amelanotic melanoma contains a few melanin granules, it is often difficult to differentiate it from other non-epithelial malignant tumors.
  • This report describes a case of amelanotic melanoma of the vulva, which was correctly diagnosed by immunohistochemical staining with the HMB-45, Melan-A antibody and for the S-100 protein.
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Aged. Antigens, Neoplasm / metabolism. Female. Humans. MART-1 Antigen. Melanoma-Specific Antigens. Neoplasm Proteins / metabolism. S100 Proteins / metabolism

  • MedlinePlus Health Information. consumer health - Vulvar Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18516330.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  • [Number-of-references] 25
  •  go-up   go-down


70. Mahajan A, Shields CL, Eagle RC Jr, Mashayekhi A, Freire JE, Shields JA: Conjunctival melanoma 3 years after radiation and chemotherapy for retinoblastoma. J Pediatr Ophthalmol Strabismus; 2007 Sep-Oct;44(5):300-2
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conjunctival melanoma 3 years after radiation and chemotherapy for retinoblastoma.
  • Excisional biopsy revealed an amelanotic melanoma of the conjunctiva with superficial orbital invasion.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Melanoma, Amelanotic / pathology. Neoplasms, Second Primary / pathology. Retinal Neoplasms / therapy. Retinoblastoma / therapy

  • Genetic Alliance. consumer health - Retinoblastoma.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. ETOPOSIDE .
  • Hazardous Substances Data Bank. CARBOPLATIN .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17913173.001).
  • [ISSN] 0191-3913
  • [Journal-full-title] Journal of pediatric ophthalmology and strabismus
  • [ISO-abbreviation] J Pediatr Ophthalmol Strabismus
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; BG3F62OND5 / Carboplatin
  •  go-up   go-down


71. Gualandri L, Betti R, Crosti C: Clinical features of 36 cases of amelanotic melanomas and considerations about the relationship between histologic subtypes and diagnostic delay. J Eur Acad Dermatol Venereol; 2009 Mar;23(3):283-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical features of 36 cases of amelanotic melanomas and considerations about the relationship between histologic subtypes and diagnostic delay.
  • BACKGROUND: Amelanotic melanomas (AM) are a difficult diagnostic challenge for clinicians.
  • OBJECTIVE: To consider the clinical presentation of AM, the histologic subtypes involved, the relationship with the diagnostic delay and the possible involvement in overall prognosis.
  • PATIENTS/METHODS: Patients who were observed in our department to be affected by cutaneous melanomas were recorded.
  • AM were divided in three main clinical types: an erythematous macule or patch on sun-exposed skin, a dermal plaque or nodule without a particular epidermal change, an exophytic nodule.
  • Only pure AM were considered.
  • Histological subtypes considered were superficial spreading melanoma, nodular melanoma, and lentigo maligna melanoma.
  • Diagnostic delay considered from when the patients first noticed the lesion on the site where the melanoma was diagnosed and when the physician or the patient first proposed the removal was recorded.
  • RESULTS: Thirty-six cases of AM out of a total of 500 melanomas (7.2%) were collected.
  • Mean Breslow thickness of AM was 1.72 mm compared to 0.61 mm of pigmented cases.
  • Nodular histotype was highly represented in AM (30.5% of cases) with respect to pigmented nodular melanomas (2.9%).
  • The diagnostic delay did not differ between amelanotic and pigmented melanomas, nor between nodular AM and nodular pigmented melanomas.
  • CONCLUSION: The great prevalence of clinical and histological nodular cases, the higher mean Breslow thickness (considered as the most important factor of prognosis) of AM compared with a not significant greater diagnostic delay may point out that a good percentage of AM have an intrinsic faster speed of growth with a worse prognosis irrespectively of the diagnostic performance.
  • [MeSH-major] Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19207640.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


72. Avilés-Izquierdo JA, Velázquez-Tarjuelo D, Lecona-Echevarría M, Lázaro-Ochaita P: [Dermoscopic features of eccrine poroma]. Actas Dermosifiliogr; 2009 Mar;100(2):133-6
MedlinePlus Health Information. consumer health - Foot Injuries and Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eccrine poroma is a benign adnexal neoplasm that clinically may mimic malignant skin tumors such as squamous cell carcinoma and amelanotic melanoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19445878.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


73. Camerin M, Rodgers MA, Kenney ME, Jori G: Photothermal sensitisation: evidence for the lack of oxygen effect on the photosensitising activity. Photochem Photobiol Sci; 2005 Mar;4(3):251-3
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Irradiation of amelanotic melanoma B78H1 cells in the presence of liposome-delivered Ni(II)-octabutoxy-naphthalocyanine with a Q-switched Ti:sapphire laser operated in a pulsed mode (850 nm, 30 ns pulses, 10 Hz, 120 mJ pulse -1) promotes a photothermal sensitization process leading to extensive cell inactivation.
  • [MeSH-minor] Air. Animals. Cell Line, Tumor. Lasers. Melanoma, Experimental / drug therapy. Metalloporphyrins / therapeutic use. Mice. Nitrogen. Time Factors

  • Hazardous Substances Data Bank. Nitrogen, Elemental .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15738991.001).
  • [ISSN] 1474-905X
  • [Journal-full-title] Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
  • [ISO-abbreviation] Photochem. Photobiol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Metalloporphyrins; 0 / octabutoxynaphthalocyaninenickel(II); N762921K75 / Nitrogen
  •  go-up   go-down


74. Zamberk-Majlis P, Velázquez-Tarjuelo D, Avilés-Izquierdo JA, Lázaro-Ochaita P: [Dermoscopic characterization of 3 cases of fibroepithelioma of Pinkus]. Actas Dermosifiliogr; 2009 Dec;100(10):899-902
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Clinical diagnosis often requires differentiation from benign lesions such as acrochordon, intradermal melanocytic nevus, neurofibroma, seborrheic keratosis, and even malignant lesions such as amelanotic melanoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20038369.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


75. Yoon TY, Kim HJ, Kim JW, Kim MK, Lee JY: Bowen's disease concealed by purpura. J Dermatol; 2007 Jan;34(1):65-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bowen's disease concealed by purpura.
  • Bowen's disease (BD) is a squamous cell carcinoma in situ characterized by a well-demarcated scaly erythematous thin plaque with an irregular outline.
  • Clinically, BD is frequently misdiagnosed as superficial basal cell carcinoma, patches of dermatitis, psoriasis, lichen planus, actinic keratosis, benign lichenoid keratosis, irritated seborrheic keratosis, viral warts, amelanotic melanoma or melanoma.
  • [MeSH-major] Bowen's Disease / complications. Purpura / complications. Scalp. Skin Neoplasms / complications

  • Genetic Alliance. consumer health - Bowen's Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17204105.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


76. LeRoy BE, Knight MC, Eggleston R, Torres-Velez F, Harmon BG: Tail-base mass from a "horse of a different color". Vet Clin Pathol; 2005;34(1):69-71
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The cytologic and histopathologic diagnoses were amelanotic melanoma.
  • In this report, we describe the cytopathologic features of an aggressive amelanotic melanoma in a non-grey horse and emphasize the unique correlation between cytologic and histologic findings.

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15732023.001).
  • [ISSN] 0275-6382
  • [Journal-full-title] Veterinary clinical pathology
  • [ISO-abbreviation] Vet Clin Pathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


77. Tundis R, Deguin B, Loizzo MR, Bonesi M, Statti GA, Tillequin F, Menichini F: Potential antitumor agents: flavones and their derivatives from Linaria reflexa Desf. Bioorg Med Chem Lett; 2005 Nov 1;15(21):4757-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The antiproliferative activity of several flavonoids isolated from Linaria reflexa Desf. (Scrophulariaceae) was evaluated in vitro by the SRB assay against the large cell lung carcinoma cell line COR-L23, hepatocellular carcinoma cell line HepG-2, renal adenocarcinoma cell line ACHN, amelanotic melanoma cell line C32, colorectal adenocarcinoma cell line Caco-2, and normal human fetal lung MRC5.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16125932.001).
  • [ISSN] 0960-894X
  • [Journal-full-title] Bioorganic & medicinal chemistry letters
  • [ISO-abbreviation] Bioorg. Med. Chem. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Chromones; 0 / Flavones; 28978-02-1 / pectolinarin
  •  go-up   go-down


78. Lovato L, Salerni G, Puig S, Carrera C, Palou J, Malvehy J: Adult xanthogranuloma mimicking basal cell carcinoma: dermoscopy, reflectance confocal microscopy and pathological correlation. Dermatology; 2010;220(1):66-70
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Juvenile xanthogranuloma in adulthood is an infrequent non-Langerhans cell histiocytosis, which may simulate malignant tumors such as basal cell carcinoma (BCC) or amelanotic melanoma.

  • Genetic Alliance. consumer health - Xanthogranuloma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19996569.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  •  go-up   go-down


79. van der Voort EA, Erceg A: [A man with a nail defect of the middle finger]. Ned Tijdschr Geneeskd; 2009;153:B132
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 64-year-old man had central nail loss and a tumour on the nailbed of his right middle finger (digitus III), due to an amelanotic malignant melanoma.
  • [MeSH-major] Fingers / pathology. Melanoma, Amelanotic / diagnosis. Skin Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19900334.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


80. Mensing C, Livingstone E, Schwarz T, Hauschild A: Eczematous malignant melanoma: a wolf in sheep's clothing. Onkologie; 2009 Apr;32(4):206-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eczematous malignant melanoma: a wolf in sheep's clothing.
  • BACKGROUND: The clinical diagnosis of amelanotic melanoma is still a challenge.
  • CASE REPORT: A 72-year-old patient was first referred to us for the excision of a melanoma of the chin.
  • In the first examination, we discovered another melanoma of the trunk.
  • Both malignancies were excised and histopathology confirmed the clinical diagnosis of melanomas with Clark level II and III, respectively.
  • Apart from these melanomas, physical examination revealed an 8 cm x 5 cm large erythematous plaque on the left upper arm.
  • Surprisingly, the pathology report showed typical features of a malignant melanoma.
  • CONCLUSIONS: Amelanotic melanoma may appear as an erythematous macula or plaque; clinical symptoms are erythema, edema, pruritus or a slow increase in size and hypopigmentation or discoloration.
  • [MeSH-major] Eczema / diagnosis. Eczema / etiology. Melanoma / complications. Melanoma / diagnosis. Skin Neoplasms / complications. Skin Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Eczema.
  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19372718.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


81. Pouckova P, Skvor J, Gotte G, Vottariello F, Slavik JT, Matousek J, Laurents DV, Libonati M, Soucek J: Some biological actions of PEG-conjugated RNase A oligomers. Neoplasma; 2006;53(1):79-85
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this work we show that the chemical conjugation of PEG to the RNase A C-dimer, and to the two RNase A trimers (NC-trimer and C- trimer) decreases the aspermatogenic activity of the oligomers while increasing their inhibitory activity on the growth of the human UB900518 amelanotic melanoma transplanted in athymic nude mice.
  • [MeSH-minor] Animals. Antispermatogenic Agents / pharmacology. Cell Line, Tumor. Dimerization. Embryo, Mammalian / drug effects. Humans. Male. Melanoma, Experimental / drug therapy. Mice. Neoplasm Transplantation. Spermatogenesis / drug effects

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16416018.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Antispermatogenic Agents; 0 / Peptide Fragments; 30IQX730WE / Polyethylene Glycols; EC 3.1.27.5 / Ribonuclease, Pancreatic
  •  go-up   go-down


82. Fulciniti F, Ascierto PA, Simeone E, Bove P, Losito S, Russo S, Gallo MS, Greggi S: Nevoid melanoma of the vagina: report of one case diagnosed on thin layer cytological preparations. Cytojournal; 2007;4:14
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nevoid melanoma of the vagina: report of one case diagnosed on thin layer cytological preparations.
  • BACKGROUND: Primary melanoma of the vagina is an extremely rare neoplasm with approximately 250 reported cases in the world literature 1234.
  • In its amelanotic variant this lesion may raise several differential diagnostic problems in cytological specimens 5.
  • The aim of this paper is to describe the cytomorphological presentation of primary vaginal melanoma on LBP since it has not previously been reported up to now, to our knowledge.
  • A cytopathological diagnosis of amelanotic melanoma was rendered.
  • CONCLUSION: amelanotic melanoma may be successfully diagnosed on LBP cytological preparations.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Int J Gynecol Cancer. 2004 May-Jun;14(3):553-7 [15228434.001]
  • [Cites] Arch Pathol Lab Med. 2003 Jan;127(1):e28-31 [12562291.001]
  • [Cites] Diagn Cytopathol. 2006 Jul;34(7):499-502 [16783771.001]
  • [Cites] Int J Gynaecol Obstet. 1989 Jun;29(2):159-64 [2568292.001]
  • [Cites] J Gynecol Obstet Biol Reprod (Paris). 1984;13(1):31-4 [6725876.001]
  • [Cites] Acta Cytol. 1981 May-Jun;25(3):272-5 [6942618.001]
  • [Cites] Semin Oncol. 1982 Dec;9(4):442-7 [7170630.001]
  • [Cites] Cancer. 1993 Mar 1;71(5):1893-7 [8448754.001]
  • [Cites] Diagn Cytopathol. 1997 Feb;16(2):151-5 [9067109.001]
  • [Cites] Acta Cytol. 1997 Mar-Apr;41(2):533-8 [9100794.001]
  • [Cites] Cancer. 1998 Sep 1;83(5):1033-40 [9731908.001]
  • [Cites] Acta Cytol. 2000 Nov-Dec;44(6):1077-80 [11127738.001]
  • [Cites] Diagn Cytopathol. 2002 May;26(5):334-9 [11992379.001]
  • [Cites] Eur J Gynaecol Oncol. 2002;23(3):195-8 [12094953.001]
  • [Cites] Am J Surg Pathol. 2002 Nov;26(11):1450-7 [12409721.001]
  • [Cites] Acta Cytol. 2002 Nov-Dec;46(6):1075-80 [12462085.001]
  • [Cites] J Clin Pathol. 2004 Sep;57(9):986-8 [15333663.001]
  • (PMID = 17608945.001).
  • [ISSN] 1742-6413
  • [Journal-full-title] CytoJournal
  • [ISO-abbreviation] Cytojournal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1934920
  •  go-up   go-down


83. Camerin M, Rello-Varona S, Villanueva A, Rodgers MA, Jori G: Metallo-naphthalocyanines as photothermal sensitisers for experimental tumours: in vitro and in vivo studies. Lasers Surg Med; 2009 Nov;41(9):665-73
Hazardous Substances Data Bank. PLATINUM .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • STUDY DESIGN/MATERIALS AND METHODS: Two octabutoxy-naphthalocyanines centrally coordinated with Pd(II) or Pt(II) ions were prepared by chemical synthesis and tested for their affinity and photothermal sensitisation activity toward a selected tumour cell line, namely B78H1 amelanotic melanoma.
  • The results thus obtained provided a basis for subsequent in vivo studies, aimed at defining the phototherapeutic efficiency of the two metallo-naphthalocyanines: the photosensitisers were i.v. injected into C57BL/6 mice bearing a subcutaneously transplanted amelanotic melanoma and at 24 hours post-injection the tumour area was irradiated by the Ti:sapphire laser using the same protocol as above detailed.
  • RESULTS: Both naphthalocyanines exhibited a high affinity for the amelanotic melanoma cells.
  • Lastly, both metallo-naphthalocyanines, and in particular the Pd(II) derivative, promoted an important response by the amelanotic melanoma, when the neoplastic tissue was irradiated by the pulsed Ti:sapphire laser.
  • [MeSH-major] Laser Therapy. Melanoma, Amelanotic / radiotherapy. Metalloporphyrins / therapeutic use. Organometallic Compounds / therapeutic use. Photochemotherapy / methods. Skin Neoplasms / radiotherapy

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • Hazardous Substances Data Bank. PALLADIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 Wiley-Liss, Inc.
  • (PMID = 19790243.001).
  • [ISSN] 1096-9101
  • [Journal-full-title] Lasers in surgery and medicine
  • [ISO-abbreviation] Lasers Surg Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Metalloporphyrins; 0 / Organometallic Compounds; 0 / palladium 5,9,14,18,23,27,32,36-octabutoxynaphthalocyanine; 49DFR088MY / Platinum; 5TWQ1V240M / Palladium
  •  go-up   go-down


84. Hansmann F, Herder V, von Altrock A, Dühlmeier R, Wohlsein P: Expression of p53 in a malignant melanoma of a goat. Berl Munch Tierarztl Wochenschr; 2010 Mar-Apr;123(3-4):174-6
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of p53 in a malignant melanoma of a goat.
  • Necropsy revealed a malignant, partly amelanotic melanoma originating from the right horn base with metastases in both frontal sinuses, urinary bladder, pleura, pericardium, second thoracic vertebra, kidney and mesenteric lymph nodes.
  • [MeSH-major] Genes, p53 / genetics. Goat Diseases / genetics. Melanoma / veterinary

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20329651.001).
  • [ISSN] 0005-9366
  • [Journal-full-title] Berliner und Münchener tierärztliche Wochenschrift
  • [ISO-abbreviation] Berl. Munch. Tierarztl. Wochenschr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


85. Harwood M, Telang GH, Robinson-Bostom L, Jellinek N: Melanoma and squamous cell carcinoma on different nails of the same hand. J Am Acad Dermatol; 2008 Feb;58(2):323-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Melanoma and squamous cell carcinoma on different nails of the same hand.
  • A case is presented of a patient with two separate and concurrent malignant neoplasms of the nail unit, on different nails on the same hand, each featuring an unusual clinical presentation: amelanotic melanoma presenting as longitudinal erythronychia and squamous cell carcinoma in situ presenting as longitudinal melanonychia.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Melanoma, Amelanotic / pathology. Nail Diseases / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Carcinoma, Squamous Cell.
  • MedlinePlus Health Information. consumer health - Nail Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18222331.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


86. Jain V, Dabir S, Shome D, Dadu T, Natarajan S: Aspergillus iris granuloma: a case report with review of literature. Surv Ophthalmol; 2009 Mar-Apr;54(2):286-91
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Differential diagnoses of a fungal granuloma, a medulloepithelioma, and an amelanotic melanoma were considered.
  • Definitive differentiation of this rare entity from a foreign body, amelanotic melanoma, and other inflammatory conditions such as sarcoidosis and tuberculosis, may be possible only on microbiological and histo-pathological evaluation.

  • MedlinePlus Health Information. consumer health - Aspergillosis.
  • Hazardous Substances Data Bank. ATROPINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19298905.001).
  • [ISSN] 0039-6257
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antifungal Agents; 0 / Aza Compounds; 0 / DNA, Fungal; 0 / Fluoroquinolones; 0 / Quinolines; 7C0697DR9I / Atropine; 8O0C852CPO / Natamycin; U188XYD42P / moxifloxacin
  • [Number-of-references] 18
  •  go-up   go-down


87. Conforti F, Loizzo MR, Statti AG, Menichini F: Cytotoxic activity of antioxidant constituents from Hypericum triquetrifolium Turra. Nat Prod Res; 2007 Jan;21(1):42-6
MedlinePlus Health Information. consumer health - Antioxidants.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Methanolic extract and pure compounds were tested against the large cell lung carcinoma cell line COR-L23, the hepatocellular carcinoma cell line HepG-2, renal cell adenocarcinoma ACHN, the amelanotic melanoma cell line C32 and normal human foetal lung MRC5.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17365688.001).
  • [ISSN] 1478-6419
  • [Journal-full-title] Natural product research
  • [ISO-abbreviation] Nat. Prod. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Antioxidants; 0 / Flavonoids; 0 / Fluorescent Dyes; 0 / Phenols; 0 / Plant Extracts; 0 / Polyphenols; 0 / Rhodamines; 2609-88-3 / lissamine rhodamine B
  •  go-up   go-down


88. Zielińska K, Kozłowska K, Cichorek M, Wachulska M: Fas and FasL expression on cells of two transplantable melanoma lines according to their different biological properties. Folia Histochem Cytobiol; 2008;46(3):337-43
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fas and FasL expression on cells of two transplantable melanoma lines according to their different biological properties.
  • In tumours (e.g. melanoma), FasL expression possibly counteracts the Fas-positive effector T cells that infiltrate into tumours, and consequently the Fas/FasL interaction can contribute to the escape of tumour cells from the systemic immune response.
  • In this study we examined differences in Fas and FasL expression on cells from the hamster melanotic melanoma line (Ma) and a more aggressive amelanotic melanoma line (Ab).
  • We also tried to find out whether the Fas/FasL expression induces an ability to undergo spontaneous apoptosis in these two transplantable melanoma lines.
  • Isolated transplantable melanoma cells were incubated for 4 and 24 hours and after that time the expression of Fas and FasL was estimated by flow cytometry.
  • The results show that there was no Fas expression, although FasL was detected on both melanoma cell lines.
  • Therefore the data reported by other authors indicate that a lack or a low level of Fas expression and an ectopic expression of FasL on melanoma cells can be an escape mechanism of the tumour, to avoid host immune responses.
  • The content of FasL-positive melanotic melanoma cells was higher than in amelanotic melanoma cells and increased with the prolongation of the incubation time.
  • FasL expression on amelanotic melanoma cells was detected after 24 hours at a level similar to that on melanotic melanoma cells after 4 hours incubation time.
  • FasL expression on melanoma cells can induce apoptosis in cytotoxic T lymphocytes and NK cells which are responsible for tumour cells elimination.
  • The results obtained suggest that the Fas/FasL system does not play any significant role in spontaneous apoptosis of two melanoma cell lines.

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19056538.001).
  • [ISSN] 1897-5631
  • [Journal-full-title] Folia histochemica et cytobiologica
  • [ISO-abbreviation] Folia Histochem. Cytobiol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antigens, CD95; 0 / Fas Ligand Protein
  •  go-up   go-down


89. Ni-Komatsu L, Orlow SJ: Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: effects of altering intracellular pH and pink-eyed dilution gene expression. Exp Eye Res; 2006 Mar;82(3):519-28
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Remarkably, this heterologous expression system recapitulates the defective processing and mistrafficking of tyrosinase observed in OCA2 albino melanocytes and certain amelanotic melanoma cells.

  • Genetic Alliance. consumer health - Albinism.
  • Genetic Alliance. consumer health - Oculocutaneous Albinism.
  • Genetic Alliance. consumer health - Oculocutaneous albinism type 2.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. L-TYROSINE .
  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16199032.001).
  • [ISSN] 0014-4835
  • [Journal-full-title] Experimental eye research
  • [ISO-abbreviation] Exp. Eye Res.
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / AR41880; United States / NEI NIH HHS / EY / EY10223
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Melanins; 0 / Membrane Transport Proteins; 0 / OCA2 protein, human; 42HK56048U / Tyrosine; EC 1.14.18.1 / Monophenol Monooxygenase
  •  go-up   go-down


90. Braga JC, Scope A, Klaz I, Mecca P, González S, Rabinovitz H, Marghoob AA: The significance of reflectance confocal microscopy in the assessment of solitary pink skin lesions. J Am Acad Dermatol; 2009 Aug;61(2):230-41
Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Solitary pink lesions often manifest nondescript clinical and dermatoscopic primary morphologic features.
  • RESULTS: Lesions included basal cell carcinoma, squamous cell carcinoma, amelanotic melanoma, and inflamed seborrheic keratosis.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Keratosis, Actinic / pathology. Melanoma / pathology. Microscopy, Confocal. Pigmentation Disorders / pathology. Skin Neoplasms / pathology


91. Ghiorzo P, Pastorino L, Pizzichetta MA, Bono R, Queirolo P, Talamini R, Annessi G, Bruno W, Nasti S, Gargiulo S, Battistuzzi L, Sini MC, Palmieri G, Scarrà GB, Italian Melanoma Intergroup: CDKN2A and MC1R analysis in amelanotic and pigmented melanoma. Melanoma Res; 2009 Jun;19(3):142-5
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CDKN2A and MC1R analysis in amelanotic and pigmented melanoma.
  • Amelanotic melanoma (AM) is a rare subtype of melanoma with little or no clinically visible pigment; it is more difficult to diagnose than pigmented melanoma (PM), and has a worse prognosis.
  • In the attempt to find a genetic explanation for the distinction between AM and PM, we conducted a case-case study, matching AM and PM patients, and testing them for germline mutations in high- (p16INK4A, p14ARF, CDK4) and low-penetrance (MC1R) melanoma susceptibility genes.
  • Similar CDKN2A mutations were found in both sets of melanomas.
  • A p14ARF splice germline mutation was detected for the first time in an Italian family with AM.
  • This rare mutation, which has been described only once previously, may be involved in predisposition to the amelanotic phenotype in combination with germline MC1R variants and coordinate somatic expression of pigmentation genes and their regulators.
  • [MeSH-major] Cyclin-Dependent Kinase Inhibitor p16 / genetics. Melanoma, Amelanotic / genetics. Receptor, Melanocortin, Type 1 / genetics. Skin Neoplasms / genetics. Tumor Suppressor Protein p14ARF / genetics
  • [MeSH-minor] Alternative Splicing. Female. Genetic Predisposition to Disease. Humans. Italy / epidemiology. Male. Mutation / genetics. Pedigree. Penetrance. Pigmentation / genetics

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19339902.001).
  • [ISSN] 1473-5636
  • [Journal-full-title] Melanoma research
  • [ISO-abbreviation] Melanoma Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Receptor, Melanocortin, Type 1; 0 / Tumor Suppressor Protein p14ARF
  •  go-up   go-down


92. Conforti F, Ioele G, Statti GA, Marrelli M, Ragno G, Menichini F: Antiproliferative activity against human tumor cell lines and toxicity test on Mediterranean dietary plants. Food Chem Toxicol; 2008 Oct;46(10):3325-32
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sixteen edible plants from Southern Italy were evaluated for their in vitro antiproliferative properties, using the sulforodamine B (SRB) assay, on four human cancer cell lines: breast cancer MCF-7, prostate cancer LNCaP, amelanotic melanoma C32 and renal adenocarcinoma ACHN.
  • Mentha aquatica showed a selective antiproliferative activity on breast cancer while significant activity was exerted by Cichorium intybus on melanoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18768152.001).
  • [ISSN] 0278-6915
  • [Journal-full-title] Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • [ISO-abbreviation] Food Chem. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Plant Extracts
  •  go-up   go-down


93. Bonesi M, Tundis R, Deguin B, Loizzo MR, Menichini F, Tillequin F, Menichini F: In vitro biological evaluation of novel 7-O-dialkylaminoalkyl cytotoxic pectolinarigenin derivatives against a panel of human cancer cell lines. Bioorg Med Chem Lett; 2008 Oct 15;18(20):5431-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The effect of novel pectolinarigenin derivatives bearing a dialkylaminoalkyl substituent at O-7 on cell proliferation was evaluated in vitro in a panel of seven human cancer cell lines including renal adenocarcinoma ACHN, amelanotic melanoma C32, colorectal adenocarcinoma Caco-2, lung large cell carcinoma COR-L23, malignant melanoma A375, lung carcinoma A549 and hepatocellular carcinoma Huh-7D12 cell lines.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18818071.001).
  • [ISSN] 1464-3405
  • [Journal-full-title] Bioorganic & medicinal chemistry letters
  • [ISO-abbreviation] Bioorg. Med. Chem. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Chromones; 0 / Flavones; 0 / Rhodamines; 0 / pectolinarigenin; 2609-88-3 / lissamine rhodamine B
  •  go-up   go-down


94. Camarillo Gómez C, Sánchez Ronco I, Encinas J: [Choroidal metastases]. An Sist Sanit Navar; 2008;31 Suppl 3:127-34

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The differential diagnosis must consider the amelanotic nevus, choroidal amelanotic melanoma, choroidal haemangioma, rear scleritis, choroidal osteoma, chorioretinitis, Harada's disease, rhegmatogenous retina detachment, uveal effusion syndrome, and serous central chorioretinopathy.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19169300.001).
  • [ISSN] 1137-6627
  • [Journal-full-title] Anales del sistema sanitario de Navarra
  • [ISO-abbreviation] An Sist Sanit Navar
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 10
  •  go-up   go-down


95. Zalaudek I, Kreusch J, Giacomel J, Ferrara G, Catricalà C, Argenziano G: How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part II. Nonmelanocytic skin tumors. J Am Acad Dermatol; 2010 Sep;63(3):377-86; quiz 387-8
Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In contrast to the rarity of amelanotic melanoma, nonmelanoma skin cancer commonly lacks pigmentation.
  • Dermoscopic vascular patterns of several nonmelanocytic nonpigmented skin tumors, such as sebaceous hyperplasia, seborrheic keratosis, clear cell acanthoma, Bowen disease, or nodular cystic basal cell carcinoma are highly specific, allowing a ready diagnosis in most cases.
  • In the second part of this review of dermoscopic vascular structures of nonpigmented skin tumors, the dermoscopic patterns associated with benign and malignant nonmelanocytic skin tumors and recommendations for the management of these tumors will be discussed.
  • [MeSH-minor] Blood Vessels / pathology. Bowen's Disease / blood supply. Bowen's Disease / diagnosis. Bowen's Disease / pathology. Carcinoma, Basal Cell / blood supply. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / pathology. Carcinoma, Squamous Cell / blood supply. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Education, Medical, Continuing. Female. Humans. Keratosis, Seborrheic / diagnosis. Keratosis, Seborrheic / pathology. Male. Melanoma, Amelanotic / blood supply. Melanoma, Amelanotic / diagnosis. Melanoma, Amelanotic / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20708470.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 43
  •  go-up   go-down


96. Baran R: The red nail--always benign? Actas Dermosifiliogr; 2009 Nov;100 Suppl 1:106-13
MedlinePlus Health Information. consumer health - Nail Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Only the former type can show histologically Bowen's disease or an amelanotic melanoma.
  • Among the polydactylous type, the nosologic position of the acantholytic and dyskeratotic naevus versus Darier's disease is still controversial.
  • Acantholytic epidermolysis bullosa looks like bullous Darier's disease, and acrokeratosis of Hopf may present also red longitudinal streaks.
  • Subungual warty dyskeratoma is rare, but other dermatoses such as lichen planus, psoriasis, mail melanoma and various tumours have to be ruled out.
  • Finally nail involvement in amyloidosis may precede the other signs of this systemic disease.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20096204.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


97. Rigano D, Conforti F, Formisano C, Menichini F, Senatore F: Comparative free radical scavenging potential and cytotoxicity of different extracts from Iris pseudopumila Tineo flowers and rhizomes. Nat Prod Res; 2009;23(1):17-25
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The chloroform extract from rhizomes demonstrated a good cytotoxic activity against amelanotic melanoma cancer cell line (C32) with an IC(50) of 57 microg mL(-1).

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19140069.001).
  • [ISSN] 1478-6427
  • [Journal-full-title] Natural product research
  • [ISO-abbreviation] Nat. Prod. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Biphenyl Compounds; 0 / Free Radical Scavengers; 0 / Picrates; 0 / Plant Extracts; 1898-66-4 / 2,2-diphenyl-1-picrylhydrazyl
  •  go-up   go-down


98. Tundis R, Loizzo MR, Bonesi M, Menichini F, Dodaro D, Passalacqua NG, Statti G, Menichini F: In vitro cytotoxic effects of Senecio stabianus Lacaita (Asteraceae) on human cancer cell lines. Nat Prod Res; 2009;23(18):1707-18
Hazardous Substances Data Bank. LINALOOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This study is aimed to evaluate the in vitro cytotoxicity of Senecio stabianus Lacaita (Asteraceae) against renal adenocarcinoma ACHN, hormone-dependent prostate carcinoma LNCaP, amelanotic melanoma C32 and human breast adenocarcinoma MCF-7 cell lines.

  • Hazardous Substances Data Bank. N-HEXANE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19921589.001).
  • [ISSN] 1478-6427
  • [Journal-full-title] Natural product research
  • [ISO-abbreviation] Nat. Prod. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hexanes; 0 / Monoterpenes; 0 / Plant Extracts; 0 / Pyrrolizidine Alkaloids; 0 / Sesquiterpenes; 2DDG612ED8 / n-hexane; 54W56MD2WD / humulene; BHW853AU9H / caryophyllene; D81QY6I88E / linalool
  •  go-up   go-down


99. Yhee JY, Hong SW, Yu CH, Doster AR, Blas-Machado U, Lyoo YS, Sur JH: Immunohistochemical application of an antibody specific for human CD1a to the diagnosis of canine mast cell tumour. J Comp Pathol; 2008 Jul;139(1):40-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This antibody did not label neoplastic cells in cases of canine histiocytoma, plasmacytoma or amelanotic melanoma; therefore, the reagent may be a valuable marker for the diagnosis of canine MCTs, especially those tumours of histological grade III.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18602642.001).
  • [ISSN] 0021-9975
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, CD1; 0 / CD1a antigen
  •  go-up   go-down


100. Dickinson RM, Young KM: Cutaneous mass aspirate from a Golden Retriever: "glandular guile". Vet Clin Pathol; 2005 Dec;34(4):421-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • On cytologic evaluation of a fine-needle aspirate of the mass, the interpretation was a malignant tumor with predominantly mesenchymal features.
  • Differentials included liposarcoma, atypical amelanotic melanoma, anaplastic sarcoma, and anaplastic carcinoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16270273.001).
  • [ISSN] 0275-6382
  • [Journal-full-title] Veterinary clinical pathology
  • [ISO-abbreviation] Vet Clin Pathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 68238-35-7 / Keratins
  •  go-up   go-down






Advertisement