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1. Nishio J, Althof PA, Bailey JM, Zhou M, Neff JR, Barr FG, Parham DM, Teot L, Qualman SJ, Bridge JA: Use of a novel FISH assay on paraffin-embedded tissues as an adjunct to diagnosis of alveolar rhabdomyosarcoma. Lab Invest; 2006 Jun;86(6):547-56
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  • [Title] Use of a novel FISH assay on paraffin-embedded tissues as an adjunct to diagnosis of alveolar rhabdomyosarcoma.
  • A valuable diagnostic adjunct and important prognostic parameter in alveolar rhabdomyosarcoma (ARMS) is the identification of translocations t(2;13)(q35;q14) and t(1;13)(p36;q14), and the associated PAX3-FKHR and PAX7-FKHR fusion transcripts, respectively.
  • Most RMS fusion gene type studies have been based on reverse transcriptase-polymerase chain reaction (RT-PCR) detection of the fusion transcript, a technique limited by RNA quality and failure of devised primer sets to detect unusual variants.
  • (1) distinguish between the two most common ARMS-associated fusion genes;.
  • (3) assess histologic components in mixed alveolar/embryonal RMS; and (4) be performed on paraffinized tissue.
  • FISH analyses of 75 specimens (40 ARMS, 16 ERMS, 8 mixed ARMS/ERMS, and 11 non-RMS tumors) using selected cosmid clone, bacterial, P1-derived, and yeast artificial chromosome probe sets were successful in all but two cases.
  • Among specimens with informative results for both FISH and RT-PCR or standard karyotyping, PAX/FKHR classification results were concordant in 94.6% (53/56).
  • The three discordant cases included one exhibiting a t(2;13) by FISH that was subsequently confirmed by repeat RT-PCR, a second showing a rearrangement of the PAX3 locus only (consistent with the presence of a PAX3 variant translocation), and a third revealing a t(2;13) by FISH that lacked this translocation cytogenetically.
  • Both alveolar and embryonal components of the mixed ARMS/ERMS subtype were negative for PAX3, PAX7, and FKHR rearrangements, a surprising finding confirmed by RT-PCR and/or conventional karyotyping.
  • These data demonstrate that FISH with newly designed probe sets is a reliable and highly specific method of detecting t(1;13) and t(2;13) in routinely processed tissue and may be useful in differentiating ARMS from other small round cell tumors.
  • The findings also suggest that FISH may be a more sensitive assay than RT-PCR in some settings, capable of revealing variant translocations.
  • [MeSH-major] In Situ Hybridization, Fluorescence. Rhabdomyosarcoma, Alveolar / diagnosis. Rhabdomyosarcoma, Alveolar / genetics

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  • (PMID = 16607381.001).
  • [ISSN] 0023-6837
  • [Journal-full-title] Laboratory investigation; a journal of technical methods and pathology
  • [ISO-abbreviation] Lab. Invest.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA36727; United States / NCI NIH HHS / CA / CA89461; United States / NCI NIH HHS / CA / CA98543
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Oncogene Proteins, Fusion
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2. Thompson JN: Coevolution: the geographic mosaic of coevolutionary arms races. Curr Biol; 2005 Dec 20;15(24):R992-4
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  • [Title] Coevolution: the geographic mosaic of coevolutionary arms races.
  • Coevolutionary arms races between species can favor exaggeration of traits for attack and defense, but relentless escalation of these arms races does not necessarily occur in all populations.

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  • (PMID = 16360677.001).
  • [ISSN] 0960-9822
  • [Journal-full-title] Current biology : CB
  • [ISO-abbreviation] Curr. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 14
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3. Balter JE, Zehr EP: Neural coupling between the arms and legs during rhythmic locomotor-like cycling movement. J Neurophysiol; 2007 Feb;97(2):1809-18

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  • [Title] Neural coupling between the arms and legs during rhythmic locomotor-like cycling movement.
  • Neuronal coupling between the arms and legs allowing coordinated rhythmic movement during locomotion is poorly understood.
  • We used the modulation of cutaneous reflexes to probe this neuronal coupling between the arms and legs using a cycling paradigm.
  • Participants performed rhythmic cycling with arms, legs, or arms and legs together.
  • We hypothesized that any contributions from the arms would be functionally linked to locomotion and would thus be phase-dependent.
  • Reflexes were evoked by electrical stimulation of the superficial peroneal nerve at the ankle, and electromyography (EMG) was recorded from muscles in the arms and legs.
  • The main finding was that the relative contribution from the arms and legs was linked to the functional state of the legs.
  • Thus the contribution from the arms was functionally gated throughout the locomotor cycle in a manner that appears to support the action of the legs.
  • Additionally, the effect of arm cycling on reflexes in leg muscles when the legs were not moving was relatively minor; full expression of the effect of rhythmic arm movement was only observed when both the arms and legs were moving.

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  • (PMID = 17065245.001).
  • [ISSN] 0022-3077
  • [Journal-full-title] Journal of neurophysiology
  • [ISO-abbreviation] J. Neurophysiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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4. Arévalo JC, Wu SH, Takahashi T, Zhang H, Yu T, Yano H, Milner TA, Tessarollo L, Ninan I, Arancio O, Chao MV: The ARMS/Kidins220 scaffold protein modulates synaptic transmission. Mol Cell Neurosci; 2010 Oct;45(2):92-100
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  • [Title] The ARMS/Kidins220 scaffold protein modulates synaptic transmission.
  • Here we report that basal synaptic transmission is regulated in an unexpected manner by the ankyrin repeat-rich membrane-spanning (ARMS/Kidins220) scaffold protein.
  • In particular, decreases in the levels of ARMS/Kidins220 in vivo led to an increase in basal synaptic transmission in the hippocampus, without affecting paired pulse facilitation.
  • One explanation to account for the effects of ARMS/Kidins220 is an interaction with the AMPA receptor subunit, GluA1, which could be observed after immunoprecipitation.
  • Importantly, shRNA and cell surface biotinylation experiments indicate that ARMS/Kidins220 levels have an impact on GluA1 phosphorylation and localization.
  • Moreover, ARMS/Kidins220 is a negative regulator of AMPAR function, which was confirmed by inward rectification assays.
  • These results provide evidence that modulation of ARMS/Kidins220 levels can regulate basal synaptic strength in a specific manner in hippocampal neurons.

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
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  • (PMID = 20547223.001).
  • [ISSN] 1095-9327
  • [Journal-full-title] Molecular and cellular neurosciences
  • [ISO-abbreviation] Mol. Cell. Neurosci.
  • [Language] ENG
  • [Grant] United States / NIDA NIH HHS / DA / DA08259; United States / NHLBI NIH HHS / HL / HL18974; United States / NICHD NIH HHS / HD / P01 HD023315; United States / NINDS NIH HHS / NS / NS21072; United States / NINDS NIH HHS / NS / R01 NS021072; United States / NIDA NIH HHS / DA / R01 DA008259; United States / NHLBI NIH HHS / HL / P01 HL018974; United States / NINDS NIH HHS / NS / R01 NS049442; United States / Intramural NIH HHS / / ; United States / NICHD NIH HHS / HD / HD23315; United States / NINDS NIH HHS / NS / NS049442; United States / NINDS NIH HHS / NS / R56 NS021072
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Kidins220 protein, mouse; 0 / Membrane Proteins; 0 / Nerve Tissue Proteins; 0 / Receptors, AMPA; 0 / glutamate receptor ionotropic, AMPA 1
  • [Other-IDs] NLM/ NIHMS213926; NLM/ PMC2923264
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5. Henes J, Oberländer Y, Tepe G, Schneider W, Balletshofer B: [Unusual reason for unilateral (corrected) Raynaud's phenomenon with intensification when the arms are elevated]. Dtsch Med Wochenschr; 2009;134 Suppl Falldatenbank:F3
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  • [Title] [Unusual reason for unilateral (corrected) Raynaud's phenomenon with intensification when the arms are elevated].
  • [Transliterated title] Einseitiges Raynaud-Phänomen mit Verstärkung bei Elevation des Arms.
  • [MeSH-major] Cervical Rib Syndrome / complications. Cervical Rib Syndrome / diagnosis. Raynaud Disease / etiology. Thromboembolism / etiology
  • [MeSH-minor] Adult. Aneurysm / complications. Aneurysm / surgery. Anticoagulants / administration & dosage. Aspirin / administration & dosage. Diagnosis, Differential. Enoxaparin / administration & dosage. Female. Fibrinolytic Agents / administration & dosage. Humans. Infusions, Intra-Arterial. Platelet Aggregation Inhibitors / administration & dosage. Ribs / abnormalities. Ribs / surgery. Subclavian Artery. Urokinase-Type Plasminogen Activator / administration & dosage

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  • [ErratumIn] Dtsch Med Wochenschr. 2009;134:E2
  • (PMID = 19319790.001).
  • [ISSN] 1439-4413
  • [Journal-full-title] Deutsche medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Dtsch. Med. Wochenschr.
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anticoagulants; 0 / Enoxaparin; 0 / Fibrinolytic Agents; 0 / Platelet Aggregation Inhibitors; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator; R16CO5Y76E / Aspirin
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6. Parelho V, Hadjur S, Spivakov M, Leleu M, Sauer S, Gregson HC, Jarmuz A, Canzonetta C, Webster Z, Nesterova T, Cobb BS, Yokomori K, Dillon N, Aragon L, Fisher AG, Merkenschlager M: Cohesins functionally associate with CTCF on mammalian chromosome arms. Cell; 2008 Feb 08;132(3):422-33
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  • [Title] Cohesins functionally associate with CTCF on mammalian chromosome arms.
  • We show that the distribution of cohesins on mammalian chromosome arms is not driven by transcriptional activity, in contrast to S. cerevisiae.
  • Recruitment by CTCF suggests a rationale for noncanonical cohesin functions and, because CTCF binding is sensitive to DNA methylation, allows cohesin positioning to integrate DNA sequence and epigenetic state.

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  • (PMID = 18237772.001).
  • [ISSN] 1097-4172
  • [Journal-full-title] Cell
  • [ISO-abbreviation] Cell
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / ; United Kingdom / Medical Research Council / / MC/ U120074328; United Kingdom / Medical Research Council / / MC/ U120027516; United Kingdom / Medical Research Council / / MC/ U120036884; United States / NIGMS NIH HHS / GM / GM59150
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CCCTC-binding factor; 0 / Cell Cycle Proteins; 0 / Chromosomal Proteins, Non-Histone; 0 / Cytokines; 0 / DNA-Binding Proteins; 0 / Nuclear Proteins; 0 / Repressor Proteins; 0 / cohesins; EC 3.1.21.1 / Deoxyribonuclease I
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7. Hanifin CT, Brodie ED, Brodie ED: Phenotypic mismatches reveal escape from arms-race coevolution. PLoS Biol; 2008 Mar 11;6(3):e60
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  • [Title] Phenotypic mismatches reveal escape from arms-race coevolution.
  • In every case of mismatch, predators were "ahead" of prey in the arms race; the converse escape of prey was never observed.
  • The emergent pattern suggests a dynamic in which interacting species experience reciprocal selection that drives arms-race escalation of both prey and predator phenotypes at a subset of localities across the interaction.
  • This coadaptation proceeds until the evolution of extreme phenotypes by predators, through genes of large effect, allows snakes to, at least temporarily, escape the arms race.

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  • (PMID = 18336073.001).
  • [ISSN] 1545-7885
  • [Journal-full-title] PLoS biology
  • [ISO-abbreviation] PLoS Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 4368-28-9 / Tetrodotoxin
  • [Other-IDs] NLM/ PMC2265764
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8. Dai Y, Grant S: Targeting multiple arms of the apoptotic regulatory machinery. Cancer Res; 2007 Apr 1;67(7):2908-11
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  • [Title] Targeting multiple arms of the apoptotic regulatory machinery.
  • Here, we summarize recent findings indicating that Mcl-1 represents a critical determinant of ABT-737 sensitivity and resistance, and that Mcl-1 down-regulation by various pharmacologic agents or genetic approaches dramatically increases ABT-737 lethality in diverse malignant cell types.
  • Collectively, these findings suggest a novel therapeutic strategy targeting multiple arms of the apoptotic machinery.
  • [MeSH-minor] Humans. Myeloid Cell Leukemia Sequence 1 Protein. Neoplasm Proteins / antagonists & inhibitors. Neoplasm Proteins / metabolism. Piperazines / pharmacology. Proto-Oncogene Proteins c-bcl-2 / antagonists & inhibitors. Proto-Oncogene Proteins c-bcl-2 / metabolism. bcl-2 Homologous Antagonist-Killer Protein / metabolism. bcl-2-Associated X Protein / metabolism

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  • (PMID = 17409392.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 100866; United States / NCI NIH HHS / CA / CA 93738; United States / NCI NIH HHS / CA / CA63753
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ABT-737; 0 / BAK1 protein, human; 0 / BAX protein, human; 0 / Biphenyl Compounds; 0 / Myeloid Cell Leukemia Sequence 1 Protein; 0 / Neoplasm Proteins; 0 / Nitrophenols; 0 / Piperazines; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Sulfonamides; 0 / bcl-2 Homologous Antagonist-Killer Protein; 0 / bcl-2-Associated X Protein
  • [Number-of-references] 20
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9. Downs-Kelly E, Shehata BM, López-Terrada D, Weaver J, Patel RM, Hartke M, Tubbs RR, Skacel M, Goldblum JR: The utility of FOXO1 fluorescence in situ hybridization (FISH) in formalin-fixed paraffin-embedded specimens in the diagnosis of alveolar rhabdomyosarcoma. Diagn Mol Pathol; 2009 Sep;18(3):138-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The utility of FOXO1 fluorescence in situ hybridization (FISH) in formalin-fixed paraffin-embedded specimens in the diagnosis of alveolar rhabdomyosarcoma.
  • Alveolar rhabdomyosarcoma (ARMS) is an aggressive neoplasm with unique t(2;13)(q35;q14) or t(1;13)(p36;q14) chromosomal translocations, resulting in PAX3/FOXO1 and PAX7/FOXO1 fusion genes, in approximately 80% of cases.
  • We report our experience with a dual-color break-apart FISH probe for the detection of FOXO1 (13q14) rearrangements in neoplasms within the differential diagnosis of ARMS, using routinely processed formalin-fixed, paraffin-embedded tissues.
  • A total of 52 sarcomas were analyzed including ARMS (n = 25), embryonal rhabdomyosarcomas (n = 8), neuroblastoma (n = 1), desmoplastic small round cell tumors (n = 2), Ewing sarcoma/primitive neuroectodermal tumors (EWS/PNET; n = 15), and round cell liposarcoma (n = 1).
  • Cytogenetics and/or reverse transcription polymerase chain reaction data were available on a subset of the ARMS (n = 11) and EWS/PNET cases (n = 5).
  • FOXO1 gene rearrangements were identified in 88% (22/25) of ARMS (mean: 91% positive cells/case; range: 50% to 100%), whereas no rearrangements were detected in the other neoplasms examined (mean: 1.4% positive cells/case; range: 0% to 4%).
  • FOXO1 (13q14) FISH on formalin-fixed, paraffin-embedded tissues samples showed excellent concordance with reverse transcription polymerase chain reaction and cytogenetic analyses in ARMS cases, demonstrated excellent specificity (100%) when applied to potential mimickers such as EWS/PNET, and played an important role in the differential diagnosis of small round cell tumors.
  • [MeSH-major] In Situ Hybridization, Fluorescence / methods. Pathology / methods. Rhabdomyosarcoma, Alveolar / diagnosis

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  • (PMID = 19704258.001).
  • [ISSN] 1533-4066
  • [Journal-full-title] Diagnostic molecular pathology : the American journal of surgical pathology, part B
  • [ISO-abbreviation] Diagn. Mol. Pathol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / FOXO1 protein, human; 0 / Fixatives; 0 / Forkhead Transcription Factors; 1HG84L3525 / Formaldehyde
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10. Fara P: Scientific coats of arms. Endeavour; 2005 Sep;29(3):101-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scientific coats of arms.
  • With their mythical creatures and arcane symbolism, coats of arms seem to have little connection with modern science.

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  • (PMID = 16098590.001).
  • [ISSN] 0160-9327
  • [Journal-full-title] Endeavour
  • [ISO-abbreviation] Endeavour
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article
  • [Publication-country] England
  • [Personal-name-as-subject] Rutherford E
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11. Lisboa S, Cerveira N, Vieira J, Torres L, Ferreira AM, Afonso M, Norton L, Henrique R, Teixeira MR: Genetic diagnosis of alveolar rhabdomyosarcoma in the bone marrow of a patient without evidence of primary tumor. Pediatr Blood Cancer; 2008 Oct;51(4):554-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic diagnosis of alveolar rhabdomyosarcoma in the bone marrow of a patient without evidence of primary tumor.
  • Alveolar rhabdomyosarcoma (ARMS) is characterized by two pathognomonic translocations, both involving the FOXO1 gene.
  • Interphase FISH analysis with specific probes evidenced a rearrangement involving the FOXO1 gene and RT-PCR identified the PAX7-FOXO1 fusion transcript.
  • These data show a case of ARMS with no evidence of primary tumor presenting the PAX7-FOXO1 fusion gene.
  • [MeSH-major] Bone Marrow Neoplasms / diagnosis. Bone Marrow Neoplasms / genetics. Rhabdomyosarcoma, Alveolar / diagnosis. Rhabdomyosarcoma, Alveolar / genetics

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18561177.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Kamioka S, Takahashi T, Kawauchi S, Adachi H, Mori Y, Fujii K, Uekusa H, Doi T: Chiral tetraazamacrocycles having four pendant-arms. Org Lett; 2009 Jun 4;11(11):2289-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chiral tetraazamacrocycles having four pendant-arms.
  • A chiral tetraazamacrocycle 9 having four pendant-arms was synthesized by repeating ring opening of an Ns-aziridine with secondary amines, followed by macrocyclization.

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  • (PMID = 19432409.001).
  • [ISSN] 1523-7052
  • [Journal-full-title] Organic letters
  • [ISO-abbreviation] Org. Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amines; 0 / Aza Compounds; 0 / Aziridines; 0 / Macrocyclic Compounds; 54P5FEX9FH / aziridine
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13. Byrne RA, Kuba MJ, Meisel DV, Griebel U, Mather JA: Does Octopus vulgaris have preferred arms? J Comp Psychol; 2006 Aug;120(3):198-204
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does Octopus vulgaris have preferred arms?
  • The octopus's generalist hunting lifestyle and the structure of their arms suggest that these animals have no need to designate specific arms for specific tasks.
  • However, octopuses also show behaviors, like exploration, in which only single or small groups of arms are involved.
  • Here the authors show that octopuses had a strong preference for anterior arm use to reach for and explore objects, which points toward a task division between anterior and posterior arms.
  • These findings give evidence for limb-specialization in an animal whose 8 arms were believed to be equipotential.

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  • [Copyright] ((c) 2006 APA, all rights reserved).
  • (PMID = 16893257.001).
  • [ISSN] 0735-7036
  • [Journal-full-title] Journal of comparative psychology (Washington, D.C. : 1983)
  • [ISO-abbreviation] J Comp Psychol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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14. Stevens MJ, Hoh JH: Conformational dynamics of neurofilament side-arms. J Phys Chem B; 2010 Jul 15;114(27):8879-86
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conformational dynamics of neurofilament side-arms.
  • The side-arms of neurofilaments (NFs) have been proposed to be highly disordered, leading to entropic repulsion that modulates interfilament spacing.
  • To gain further insight into the dynamics and organization of the side-arms, we performed molecular dynamics simulations of neurofilament brushes using a coarse-grained model.
  • Further, we find cross-correlations between neurofilament side-arms within the brush, even for the NF-L polymers.

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  • (PMID = 20557103.001).
  • [ISSN] 1520-5207
  • [Journal-full-title] The journal of physical chemistry. B
  • [ISO-abbreviation] J Phys Chem B
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neurofilament Proteins
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15. Endo M, Hidaka K, Kato T, Namba K, Sugiyama H: DNA prism structures constructed by folding of multiple rectangular arms. J Am Chem Soc; 2009 Nov 4;131(43):15570-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] DNA prism structures constructed by folding of multiple rectangular arms.
  • Novel multiarm DNA structures were designed using two-dimensional DNA origami scaffolds, and these structures were folded into hollow three-dimensional (3D) structures by introducing connection strands into the arms.
  • The opening of the prism structures was examined by high-speed AFM imaging, which showed the dissociation of the connecting arms in the 3D structures.

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  • (PMID = 19824672.001).
  • [ISSN] 1520-5126
  • [Journal-full-title] Journal of the American Chemical Society
  • [ISO-abbreviation] J. Am. Chem. Soc.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-49-2 / DNA
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16. Indelicato DJ, Keole SR, Shahlaee AH, Morris CG, Gibbs CP, Scarborough MT, Islam S, Marcus RB: Ewing tumors of the chest wall: Local control and long-term outcomes. J Clin Oncol; 2009 May 20;27(15_suppl):e21501

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pts characteristics: median age 41 (19-80 y), male/female 19/12; symptoms at diagnosis: dyspnoea (42%), chest and shoulder pain (39%), cough (35%), hemophtoae (13%), discomfort (10%).
  • 26 lung sarcomas presented as a singular mass in 23 cases and as a metastatic disease in 3.
  • The histology were: peripheral nerve tumour 7, leiomyosarcoma 4, MFH 2, fibrosarcoma 2, liposarcoma 1, angiosarcoma 2, undifferentiated sarcoma 1, solitary fibrous tumour 2, rhabdomyosarcoma 2, synovialsarcoma 2, pulmonary artery sarcoma 1, pleuropolmonary blastoma 1, malignant hemangiopericytoma 1, mixoid chondrosarcoma 1, ectopic osteosarcoma 1, aggressive fibromatosis 1.
  • Only 4 pts received neoadjuvant chemotherapy, 11 adjuvant CT, 5 exclusive CT + RT for inoperable disease.
  • Of these only 8 are alive (2 with disease).
  • Volume of disease, complete resection and grading are the dominant prognostic factors.

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  • (PMID = 27963390.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Magnan HD, Chou T, LaQuaglia MP, Gerald W, Ladanyi M, Merchant MS: Elevated expression of VEGFR-2 and VEGFA in desmoplastic small round cell tumor (DSRCT) and activity of bevacizumab and irinotecan in a xenograft model of DSRCT. J Clin Oncol; 2009 May 20;27(15_suppl):10016

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: RNA was extracted from frozen tumor samples (DSRCT, alveolar soft part sarcoma, alveolar rhabdomyosarcoma, synovial sarcoma, and Ewing sarcoma) and a human DSRCT cell line, JN-DSRCT.

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  • (PMID = 27962501.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Comandone A, Boglione A, Pochettino P, Berno E, Inguì M, Papotti M, Borasio P, Maggi G, Brach Del Prever E, Gino G: Primary sarcomas of the lungs and mediastinum: Clinicopathological study and therapy results of Piedmontese Group for Sarcomas. J Clin Oncol; 2009 May 20;27(15_suppl):e21509

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pts characteristics: median age 41 (19-80 y), male/female 19/12; symptoms at diagnosis: dyspnoea (42%), chest and shoulder pain (39%), cough (35%), hemophtoae (13%), discomfort (10%).
  • 26 lung sarcomas presented as a singular mass in 23 cases and as a metastatic disease in 3.
  • The histology were: peripheral nerve tumour 7, leiomyosarcoma 4, MFH 2, fibrosarcoma 2, liposarcoma 1, angiosarcoma 2, undifferentiated sarcoma 1, solitary fibrous tumour 2, rhabdomyosarcoma 2, synovialsarcoma 2, pulmonary artery sarcoma 1, pleuropolmonary blastoma 1, malignant hemangiopericytoma 1, mixoid chondrosarcoma 1, ectopic osteosarcoma 1, aggressive fibromatosis 1.
  • Only 4 pts received neoadjuvant chemotherapy, 11 adjuvant CT, 5 exclusive CT + RT for inoperable disease.
  • Of these only 8 are alive (2 with disease).
  • Volume of disease, complete resection and grading are the dominant prognostic factors.

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  • (PMID = 27963441.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Zubarev ER, Xu J, Sayyad A, Gibson JD: Amphiphilic gold nanoparticles with V-shaped arms. J Am Chem Soc; 2006 Apr 19;128(15):4958-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amphiphilic gold nanoparticles with V-shaped arms.
  • Here we describe a very efficient method to produce well-defined amphiphilic gold nanoparticles (Au NPs) with an equal number of hydrophobic and hydrophilic arms which are distributed along the surface of a 2-nm gold core in an alternating fashion.

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  • (PMID = 16608322.001).
  • [ISSN] 0002-7863
  • [Journal-full-title] Journal of the American Chemical Society
  • [ISO-abbreviation] J. Am. Chem. Soc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. John IA: The impact of small arms on health in Nigeria. Med Confl Surviv; 2005 Oct-Dec;21(4):312-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The impact of small arms on health in Nigeria.
  • Nigeria, the most populous Black country in the world, though it has contributed to the welfare of other African countries, is plagued by internal conflicts with small arms.
  • Over a million illegal small arms circulate in Nigeria in the hands of militant groups.
  • Quality health care is unavailable in much of the country, and small arms injuries often overstretch emergency health care.
  • A national committee has been set up to implement the ECOWAS moratorium on small arms and light weapons, but much remains to be done.

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  • (PMID = 16450652.001).
  • [ISSN] 1362-3699
  • [Journal-full-title] Medicine, conflict, and survival
  • [ISO-abbreviation] Med Confl Surviv
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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21. Leng M, Besusso D, Jung SY, Wang Y, Qin J: Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase. Cell Cycle; 2008 05 15;7(10):1480-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase.
  • In this study, we report the identification of a putative ATPase that targets Plk1 to chromosome arms during mitosis.
  • PICH (Plk1-interacting checkpoint "helicase") displays a temporal localization on chromosome arms and kinetochores during early mitosis.
  • Interaction with PICH recruits Plk1 to chromosome arms and disruption of this interaction abolishes Plk1 localization on chromosome arms.
  • Our study provides a mechanism for targeting Plk1 to chromosome arms and suggests that the PICH ATPase activity is important for the regulation of mitotic chromosome architecture.

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  • (PMID = 18418076.001).
  • [ISSN] 1551-4005
  • [Journal-full-title] Cell cycle (Georgetown, Tex.)
  • [ISO-abbreviation] Cell Cycle
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA84199
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / DNA Primers; 0 / Proto-Oncogene Proteins; 0 / RNA, Small Interfering; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / polo-like kinase 1; EC 3.6.4.- / DNA Helicases; EC 3.6.4.12 / ERCC6L protein, human
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22. Eaker S, Johnson M, Jenkins J, Bauer M, Little S: Detection of CFTR mutations using ARMS and low-density microarrays. Biosens Bioelectron; 2005 Dec 15;21(6):933-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Detection of CFTR mutations using ARMS and low-density microarrays.
  • The amplification refractory mutation system (ARMS) is routinely used for the identification of specific mutations within genomes.
  • This PCR-based assay, although simple, is performed at a low-throughput scale, usually requiring gel-electrophoresis for the identification of specific mutations.
  • We have applied the ARMS technology to a low-density microarray system to facilitate the needs of the medical clinic; high-throughput capabilities and ease-of-use.
  • Mutations within the cystic fibrosis transmembrane regulator (CFTR) gene (DeltaF508, 1717-1G>A, G542X, 621+1G>T, and N1303K) were detected by multiplex-ARMS-PCR, and fragments were post-PCR labeled with Cy5.
  • Amine-modified probes specific for both the wild-type and mutant forms of each mutation site were attached to glass substrates.
  • The novel combination of the ARMS and low-density microarray technologies allows for a high-throughput, simple means to rapidly identify multiple known mutations for many genetic diseases including cystic fibrosis.
  • [MeSH-minor] Equipment Design. Equipment Failure Analysis. Genetic Testing / methods. Humans. Nucleic Acid Amplification Techniques / instrumentation. Reproducibility of Results. Sensitivity and Specificity

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  • (PMID = 15890513.001).
  • [ISSN] 0956-5663
  • [Journal-full-title] Biosensors & bioelectronics
  • [ISO-abbreviation] Biosens Bioelectron
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 126880-72-6 / Cystic Fibrosis Transmembrane Conductance Regulator
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23. Seiz M, Radek M, Buslei R, Kreutzer J, Hofmann B, Kottler U, Doerfler A, Nimsky C, Fahlbusch R: Alveolar rhabdomyosarcoma of the clivus with intrasellar expansion: Case report. Zentralbl Neurochir; 2006 Nov;67(4):219-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Alveolar rhabdomyosarcoma of the clivus with intrasellar expansion: Case report.
  • Rhabdomyosarcomas are common tumors of the head and neck region in children.
  • Transsphenoidal biopsy was performed and histopathological examination as well as molecular diagnostics confirmed the diagnosis of an alveolar rhabdomyosarcoma (ARMS).
  • Staging identified a metastatic lesion in the fourth thoracic vertebra resulting in the diagnosis of stage IV disease.
  • [MeSH-major] Pituitary Neoplasms / surgery. Rhabdomyosarcoma / surgery

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  • (PMID = 17139605.001).
  • [ISSN] 0044-4251
  • [Journal-full-title] Zentralblatt für Neurochirurgie
  • [ISO-abbreviation] Zentralbl. Neurochir.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Antineoplastic Agents, Phytogenic; 12629-01-5 / Human Growth Hormone; 6PLQ3CP4P3 / Etoposide; 9002-60-2 / Adrenocorticotropic Hormone; BG3F62OND5 / Carboplatin
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24. Mahmudi-Azer S: Arms trade and its impact on global health. Theor Med Bioeth; 2006;27(1):81-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Arms trade and its impact on global health.
  • The most obvious adverse impact of the arms trade on health is loss of life and maiming from the use of weapons in conflicts.
  • This article outlines the socio-economic impact of the global arms trade in general and the damage done to human health and the environment, specifically.
  • [MeSH-minor] Developed Countries. Developing Countries. Humans. Internationality. Social Environment. United States

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  • [Cites] BMJ. 1995 Dec 23-30;311(7021):1677-80 [8541755.001]
  • [Cites] Med War. 1995 Apr-Jun;11(2):99-104 [7752994.001]
  • [Cites] JAMA. 1991 Aug 7;266(5):688-92 [2072480.001]
  • [Cites] Lancet. 2004 Nov 20-26;364(9448):1857-64 [15555665.001]
  • [Cites] Lancet. 1996 Feb 17;347(8999):450-1 [8618490.001]
  • (PMID = 16532304.001).
  • [ISSN] 1573-0980
  • [Journal-full-title] Theoretical medicine and bioethics
  • [ISO-abbreviation] Theor Med Bioeth
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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25. Li X, Ding X, Chu B, Ding G, Gu S, Qian L, Wang Y, Zhou Q: Molecular authentication of Alisma orientale by PCR-RFLP and ARMS. Planta Med; 2007 Jan;73(1):67-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular authentication of Alisma orientale by PCR-RFLP and ARMS.
  • Polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis and amplification refractory mutation system (ARMS) analysis were applied to the ITS region for the identification of A. orientale.
  • A restriction site for PSTI useful for PCR-RFLP analysis was detected and a pair of diagnostic primers DFZX-JB02S and DFZX-JB02X were designed for ARMS.

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  • (PMID = 17109255.001).
  • [ISSN] 0032-0943
  • [Journal-full-title] Planta medica
  • [ISO-abbreviation] Planta Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Plant; 0 / DNA, Ribosomal Spacer
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26. Lawrence JM: Energetic costs of loss and regeneration of arms in stellate echinoderms. Integr Comp Biol; 2010 Oct;50(4):506-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Energetic costs of loss and regeneration of arms in stellate echinoderms.
  • Loss of arms has energetic consequences for stellate echinoderms (crinoids, ophiuroids, and asteroids).
  • The energetic cost of losing an arm includes loss of investment, decrease in ability to obtain nutrients and allocation of nutrients to regeneration of the lost arms at a cost to other body compartments.
  • Loss of investment is greater in asteroids than in crinoids and ophiuroids because of greater development of the body wall and presence of gonads and pyloric caeca in the arms.
  • The cost of regeneration of organic matter in an arm can be estimated from the amount of organic matter present in intact arms and the cost of anabolism.
  • A major energetic cost of loss of arms that affects regeneration is decrease in food consumption.
  • They are also a good model for the study of the evolutionary significance of regeneration by comparing individuals that have lost arms and are regenerating them to those that have lost arms and are not.
  • The difference in the frequency of loss of arms of species is related to the difference in availability of food and the ability to feed that affect the capacity for re-investment in the lost arm.

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  • [Copyright] © The Author 2010. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved.
  • (PMID = 21558218.001).
  • [ISSN] 1557-7023
  • [Journal-full-title] Integrative and comparative biology
  • [ISO-abbreviation] Integr. Comp. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
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27. Lazzarini L, Salviati G, Fabbri F, Zha M, Calestani D, Zappettini A, Sekiguchi T, Dierre B: Unpredicted nucleation of extended zinc blende phases in wurtzite ZnO nanotetrapod arms. ACS Nano; 2009 Oct 27;3(10):3158-64

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unpredicted nucleation of extended zinc blende phases in wurtzite ZnO nanotetrapod arms.
  • The conventional picture is that ZnO arms are thermodynamically stable only in the wurtzite phase.
  • Here, we provide the first experimental evidence of unpredicted extended zinc blend phases (50-60 nm long) embedded in the arms of ZnO wurtzite tetrapods.

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  • (PMID = 19739604.001).
  • [ISSN] 1936-086X
  • [Journal-full-title] ACS nano
  • [ISO-abbreviation] ACS Nano
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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28. Babakhanian AR, Babakhanian RB, Isakov VD: [Forensic-medical aspects of injuries inflicted by nonlethal arms]. Sud Med Ekspert; 2005 Jul-Aug;48(4):5-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Forensic-medical aspects of injuries inflicted by nonlethal arms].
  • Special literature (surgical, forensic-medical and criminalistic) is reviewed on classification, mechanisms of a harmful action and characteristics of injuries inflicted by non-lethal arms.
  • Some details of such arms construction and damaging action are given.

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  • (PMID = 16130323.001).
  • [ISSN] 0039-4521
  • [Journal-full-title] Sudebno-meditsinskaia ekspertiza
  • [ISO-abbreviation] Sud. Med. Ekspert.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Russia (Federation)
  • [Number-of-references] 21
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29. Ishikawa T, Sakakibara H, Oiwa K: The architecture of outer dynein arms in situ. J Mol Biol; 2007 May 18;368(5):1249-58

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The architecture of outer dynein arms in situ.
  • Outer dynein arms, the force generators for axonemal motion, form arrays on microtubule doublets in situ, although they are bouquet-like complexes with separated heads of multiple heavy chains when isolated in vitro.
  • To understand how the three heavy chains are folded in the array, we reconstructed the detailed 3D structure of outer dynein arms of Chlamydomonas flagella in situ by electron cryo-tomography and single-particle averaging.
  • The neighboring outer dynein arms are connected through two filamentous structures: one at the exterior of the axoneme and the other through the alpha-tail.

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  • (PMID = 17391698.001).
  • [ISSN] 0022-2836
  • [Journal-full-title] Journal of molecular biology
  • [ISO-abbreviation] J. Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 3.6.4.2 / Dyneins
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30. Toju H, Sota T: Do arms races punctuate evolutionary stasis? Unified insights from phylogeny, phylogeography and microevolutionary processes. Mol Ecol; 2009 Sep;18(18):3940-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Do arms races punctuate evolutionary stasis? Unified insights from phylogeny, phylogeography and microevolutionary processes.
  • Here, we examined a novel hypothesis that evolutionary stasis is punctuated by co-evolutionary arms races, which continuously alter adaptive peaks and landscapes.
  • A coalescent analysis of a species, Curculio camelliae, the mouthpart of which has diverged considerably among populations because of an arms race with its host plant, further suggested that major evolutionary shifts had occurred within 7000 generations.

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  • (PMID = 19732333.001).
  • [ISSN] 1365-294X
  • [Journal-full-title] Molecular ecology
  • [ISO-abbreviation] Mol. Ecol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
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31. Bremer AK, Sennwald GR, Favre P, Jacob HA: Moment arms of forearm rotators. Clin Biomech (Bristol, Avon); 2006 Aug;21(7):683-91

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Moment arms of forearm rotators.
  • This investigation aims at determining the moment arms of muscles that contribute to pronation and supination at three different angles of elbow flexion throughout the entire range of forearm rotation.
  • METHODS: Muscle moment arms were derived from tendon excursions that were recorded on a full-size epoxy model of the radioulnar complex.
  • FINDINGS: Moment arms of all major supinators exhibit peak values in 40-50 degrees of pronation, for all three positions of the elbow.

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  • (PMID = 16678316.001).
  • [ISSN] 0268-0033
  • [Journal-full-title] Clinical biomechanics (Bristol, Avon)
  • [ISO-abbreviation] Clin Biomech (Bristol, Avon)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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32. Xu T, Lu R, Liu X, Chen P, Qiu X, Zhao Y: Porphyrins with four monodisperse oligocarbazole arms: facile synthesis and photophysical properties. J Org Chem; 2008 Mar 7;73(5):1809-17

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Porphyrins with four monodisperse oligocarbazole arms: facile synthesis and photophysical properties.
  • A series of novel monodisperse, well-defined, star-shaped molecules T(OCAn)Ps (n = 2-6) with a central porphyrin core and four oligocarbazole arms are synthesized from the corresponding formyl-substituted oligocarbazoles via Adler reaction.
  • The obtained star-shaped porphyrins are intrinsically two-dimensional nanosized molecules, and the diameter of compound T(OCA6)P is 7.4 nm, representing one of the largest known star-shaped conjugated systems.
  • Their photophysical properties have been investigated by absorption and steady-state fluorescence spectroscopy, together with the corresponding monodisperse oligocarbazole aldehyde precursors.
  • It is found that the light-harvesting capability of T(OCAn)Ps increases with the increasing length of the arms and reaches the maximum when n = 6.
  • A selective excitation of the oligocarbazole arms leads to the typical emission from the porphyrin cores, indicating occurrence of photoinduced intramolecular energy transfer, and the energy transfer efficiency decreases from T(OCA2)P to T(OCA6)P owing to the Förster energy-transfer process.
  • 3 nm in our system.
  • Notably, the monodisperse oligocarbazole aldehyde precursors give twisted intramolecular charge-transfer (TICT) excited states and luminescence in polar solvents with large Stokes shifts.

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  • (PMID = 18229940.001).
  • [ISSN] 0022-3263
  • [Journal-full-title] The Journal of organic chemistry
  • [ISO-abbreviation] J. Org. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Ingle RA, Carstens M, Denby KJ: PAMP recognition and the plant-pathogen arms race. Bioessays; 2006 Sep;28(9):880-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] PAMP recognition and the plant-pathogen arms race.
  • Plants have evolved systems analogous to animal innate immunity that recognise pathogen-associated molecular patterns (PAMPs).
  • PAMP detection is an important component of non-host resistance in plants and serves as an early warning system for the presence of potential pathogens.
  • Binding of a PAMP to the appropriate pattern recognition receptor leads to downstream signalling events and, ultimately, to the induction of basal defence systems.
  • To overcome non-host resistance, pathogens have evolved effectors that target specific regulatory components of the basal defence system.
  • In turn, this has led to the evolution in plants of cultivar-specific resistance mediated by R proteins, which guard the targets of effectors against pathogen manipulation; the arms race continues.

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  • [Copyright] (c) 2006 Wiley periodicals, Inc.
  • (PMID = 16937346.001).
  • [ISSN] 0265-9247
  • [Journal-full-title] BioEssays : news and reviews in molecular, cellular and developmental biology
  • [ISO-abbreviation] Bioessays
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 12777-81-0 / Flagellin
  • [Number-of-references] 78
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34. Morocho AM, Karamyshev V, Shcherbinina O, Polushin N: Biotin-labeled oligonucleotides with extraordinarily long tethering arms. Methods Mol Biol; 2005;288:225-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Biotin-labeled oligonucleotides with extraordinarily long tethering arms.
  • We describe synthesis of four novel biotin phosphoramidites with tethering arms ranging from 20 to 74 atoms in length.

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  • (PMID = 15333906.001).
  • [ISSN] 1064-3745
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Oligonucleotides; 6SO6U10H04 / Biotin
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35. Caro JJ, Ishak KJ: No head-to-head trial? simulate the missing arms. Pharmacoeconomics; 2010;28(10):957-67

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] No head-to-head trial? simulate the missing arms.
  • In this article, we describe the simulated treatment comparison (STC) approach to incorporating 'missing arms' into an existing trial.
  • The simulation is used to add the missing arms to the index trial and estimate the results that would have been obtained in a head-to-head trial.

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  • (PMID = 20831304.001).
  • [ISSN] 1179-2027
  • [Journal-full-title] PharmacoEconomics
  • [ISO-abbreviation] Pharmacoeconomics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
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36. Birch PR, Rehmany AP, Pritchard L, Kamoun S, Beynon JL: Trafficking arms: oomycete effectors enter host plant cells. Trends Microbiol; 2006 Jan;14(1):8-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Trafficking arms: oomycete effectors enter host plant cells.
  • Evidence of diversifying selection in these genes and their cognate plant host resistance genes suggests a molecular "arms race" as plants and oomycetes attempt to achieve and evade detection, respectively.

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  • (PMID = 16356717.001).
  • [ISSN] 0966-842X
  • [Journal-full-title] Trends in microbiology
  • [ISO-abbreviation] Trends Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Algal Proteins; 0 / Plant Proteins
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37. Lappin JM, Morgan KD, Valmaggia LR, Broome MR, Woolley JB, Johns LC, Tabraham P, Bramon E, McGuire PK: Insight in individuals with an At Risk Mental State. Schizophr Res; 2007 Feb;90(1-3):238-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Insight in individuals with an At Risk Mental State.
  • PURPOSE: On average, people with an At Risk Mental State (ARMS) for psychosis are more willing to seek and accept clinical help than patients with psychotic disorders, suggesting that insight in this group is relatively less impaired.
  • We compared the level and quality of insight in the ARMS and in first episode psychosis.
  • MATERIALS AND METHODS: Insight about illness was assessed in subjects with an ARMS and in patients with first episode psychosis (FEP) who were and were not help-seeking, using the Schedule for Assessment of Insight (SAI-E).
  • RESULTS: Insight was impaired in ARMS subjects, but there was considerable variability in the insight displayed between subjects.
  • Compared to FEP subjects, ARMS subjects showed greater insight, particularly with respect to Symptom Relabelling.
  • ARMS subjects were more likely to interpret anomalous experiences as symptoms of illness, and to perceive themselves as needing treatment.
  • CONCLUSIONS: Insight in people at high risk for psychosis is impaired, despite the fact that they are help-seeking.
  • Insight varies between subjects, highlighting the need to comprehensively assess all aspects of insight in those with an ARMS.
  • ARMS subjects are impaired in their ability to appraise anomalous experiences as symptoms of illness, but much less impaired than FEP subjects.
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Psychometrics / statistics & numerical data. Reference Values. Reproducibility of Results. Risk Assessment. Schizotypal Personality Disorder / diagnosis. Schizotypal Personality Disorder / genetics. Schizotypal Personality Disorder / psychology

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  • (PMID = 17215109.001).
  • [ISSN] 0920-9964
  • [Journal-full-title] Schizophrenia research
  • [ISO-abbreviation] Schizophr. Res.
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0901310; United Kingdom / Department of Health / / PDA/02/06/016
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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38. Kuntner M, Coddington JA, Schneider JM: Intersexual arms race? Genital coevolution in nephilid spiders (Araneae, Nephilidae). Evolution; 2009 Jun;63(6):1451-63

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intersexual arms race? Genital coevolution in nephilid spiders (Araneae, Nephilidae).
  • Although the results are compatible with both recently favored sexual selection hypotheses, sexually antagonistic coevolution, and cryptic female choice, the evidence of strong intersexual conflict and genitalic damage in both sexes is more easily explained as sexually antagonistic coevolution due to an evolutionary arms race.

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  • (PMID = 19492993.001).
  • [ISSN] 1558-5646
  • [Journal-full-title] Evolution; international journal of organic evolution
  • [ISO-abbreviation] Evolution
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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39. Tian Y, He Y, Ribbe AE, Mao C: Preparation of branched structures with long DNA duplex arms. Org Biomol Chem; 2006 Sep 21;4(18):3404-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preparation of branched structures with long DNA duplex arms.
  • Branched structures with long DNA duplex arms have been constructed through biotin-streptavidin binding and characterized by gel electrophoresis and atomic force microscopy (AFM) imaging.

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  • (PMID = 17036131.001).
  • [ISSN] 1477-0520
  • [Journal-full-title] Organic & biomolecular chemistry
  • [ISO-abbreviation] Org. Biomol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 6SO6U10H04 / Biotin; 9007-49-2 / DNA; 9013-20-1 / Streptavidin
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40. Abel SM: Barriers to hearing conservation programs in combat arms occupations. Aviat Space Environ Med; 2008 Jun;79(6):591-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Barriers to hearing conservation programs in combat arms occupations.
  • A focus group study involving four combat arms occupations was carried out to probe individuals' knowledge, attitudes, and behaviors relating to hearing loss prevention to find ways to improve compliance.

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  • (PMID = 18581943.001).
  • [ISSN] 0095-6562
  • [Journal-full-title] Aviation, space, and environmental medicine
  • [ISO-abbreviation] Aviat Space Environ Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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41. López-Menéndez C, Gascón S, Sobrado M, Vidaurre OG, Higuero AM, Rodríguez-Peña A, Iglesias T, Díaz-Guerra M: Kidins220/ARMS downregulation by excitotoxic activation of NMDARs reveals its involvement in neuronal survival and death pathways. J Cell Sci; 2009 Oct 1;122(Pt 19):3554-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kidins220/ARMS downregulation by excitotoxic activation of NMDARs reveals its involvement in neuronal survival and death pathways.
  • A shared downstream effector for neurotrophin- and ephrin-receptor signaling is kinase D-interacting substrate of 220 kDa (Kidins220), also known as ankyrin repeat-rich membrane spanning (ARMS).
  • Because this molecule is obligatory for neurotrophin-induced differentiation, we investigated whether Kidins220/ARMS and NMDAR functions were related.
  • Here, we identify an association between these proteins and discover that excitotoxicity, a specific form of neuronal death induced by NMDAR overstimulation, dramatically decreases Kidins220/ARMS levels in cortical neurons and in a model of cerebral ischemia.
  • Kidins220/ARMS downregulation is triggered by overactivation of NMDARs containing NR2B subunits and subsequent Ca(2+) influx, and involves a dual mechanism: rapid cleavage by the Ca(2+)-dependent protease calpain and calpain-independent silencing of Kidins220/Arms gene transcription.
  • Additionally, Kidins220/ARMS knockdown decreases ERK activation and basal neuronal viability, and enhances neuronal death under excitotoxic conditions.
  • Our results demonstrate Kidins220/ARMS participation in neuronal life and death pathways, and constitute the first report of its regulation under pathological conditions.
  • [MeSH-major] Brain Ischemia / physiopathology. Down-Regulation. Membrane Proteins / metabolism. Neurons / cytology. Phosphoproteins / metabolism. Receptors, N-Methyl-D-Aspartate / metabolism
  • [MeSH-minor] Animals. Cell Death. Cell Survival. Cells, Cultured. Disease Models, Animal. Humans. Male. Protein Binding. Rats. Rats, Sprague-Dawley. Rats, Wistar

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  • (PMID = 19759287.001).
  • [ISSN] 1477-9137
  • [Journal-full-title] Journal of cell science
  • [ISO-abbreviation] J. Cell. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Kidins220 protein, rat; 0 / Membrane Proteins; 0 / Phosphoproteins; 0 / Receptors, N-Methyl-D-Aspartate
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42. Borgwardt SJ, Riecher-Rössler A, Dazzan P, Chitnis X, Aston J, Drewe M, Gschwandtner U, Haller S, Pflüger M, Rechsteiner E, D'Souza M, Stieglitz RD, Radü EW, McGuire PK: Regional gray matter volume abnormalities in the at risk mental state. Biol Psychiatry; 2007 May 15;61(10):1148-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regional gray matter volume abnormalities in the at risk mental state.
  • BACKGROUND: Individuals with an At Risk Mental State (ARMS) have a very high risk of developing a psychotic disorder but the basis of this risk is unclear.
  • METHODS: Thirty-five individuals with an ARMS, 25 patients with first episode schizophrenia, and 22 healthy volunteers were studied using a 1.5T MRI scanner.
  • Twelve (34%) of the ARMS group developed schizophrenia in the 2 years subsequent to scanning.
  • In these regions, the volume in the ARMS group was smaller than in volunteers but not significantly different from that in the first episode (FE) group.
  • Direct comparison of the ARMS and control groups revealed additional areas of reduced volume in the left medial temporal cortex.
  • Within the ARMS group, those subjects who later developed psychosis had less gray matter than subjects who did not in the right insula, inferior frontal and superior temporal gyrus.
  • CONCLUSIONS: The ARMS was associated with reductions in gray matter volume in areas that are also reduced in schizophrenia, suggesting that these are a correlate of an increased vulnerability to psychosis.
  • Volumetric differences within the ARMS group may be related to the subsequent onset of schizophrenia in a subset of those at high risk.
  • [MeSH-major] Brain / pathology. Genetic Predisposition to Disease / genetics. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Schizophrenia / genetics. Schizophrenic Psychology. Schizotypal Personality Disorder / genetics
  • [MeSH-minor] Adolescent. Adult. Cerebral Cortex / pathology. Dominance, Cerebral / physiology. Early Diagnosis. Female. Follow-Up Studies. Gyrus Cinguli / pathology. Humans. Male. Psychiatric Status Rating Scales. Reference Values. Risk

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  • (PMID = 17098213.001).
  • [ISSN] 0006-3223
  • [Journal-full-title] Biological psychiatry
  • [ISO-abbreviation] Biol. Psychiatry
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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43. Liao YH, Hsu SM, Huang PH: ARMS depletion facilitates UV irradiation induced apoptotic cell death in melanoma. Cancer Res; 2007 Dec 15;67(24):11547-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] ARMS depletion facilitates UV irradiation induced apoptotic cell death in melanoma.
  • Here, we report that ankyrin repeat-rich membrane spanning (ARMS), a transmembrane protein abundant in the developing and adult neural tissues, is overexpressed in melanoma, a tumor ontogenetically originating from neural crest.
  • Immunohistochemical study of 79 melanocytic lesions showed significantly increased expression of ARMS in primary malignant melanomas (92.9%) and metastatic melanoma (60.0%) in comparison with benign nevocellular nevi (26.7%).
  • To investigate the role of ARMS in melanoma formation, murine B16F0 melanoma cells with stable knockdown of ARMS were established by RNA interference.
  • Down-regulation of ARMS resulted in significant inhibition of anchorage-independent growth in soft agar and restrictive growth of melanoma in severe combined immunodeficient mice.
  • Importantly, depletion of ARMS facilitated UVB-induced apoptosis in melanoma cells through inactivation of mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/ERK.
  • Addition of MEK inhibitor PD98059 further sensitized ARMS-depleted melanoma cells to UVB-induced apoptosis, whereas constitutively active MEK rescued ARMS-depleted cells from apoptosis.
  • We further showed that BRAF, a downstream signaling molecule of ARMS in ERK pathway, is not mutated as a constitutively active form in acral lentiginous melanoma; in contrast, BRAF(T1799A) mutation, which leads to constitutive activation of ERK signaling, was detected in 57.1% of superficial spreading melanoma.
  • Our study suggests that overexpression of ARMS per se serves as one mechanism to promote melanoma formation by preventing stress-induced apoptotic death mediated by the MEK/ERK signaling pathway, especially in acral lentiginous melanoma, most of which does not harbor BRAF mutation.
  • [MeSH-major] Melanoma / physiopathology. Membrane Proteins / physiology. Nerve Tissue Proteins / physiology
  • [MeSH-minor] Animals. Apoptosis. Cell Line, Tumor. Foreskin. Humans. Infant, Newborn. Male. Melanocytes / cytology. Melanocytes / physiology. Mice. Mice, SCID. Mutation. Proto-Oncogene Proteins B-raf / genetics. RNA Interference. Reverse Transcriptase Polymerase Chain Reaction. Transfection. Ultraviolet Rays

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  • (PMID = 18089783.001).
  • [ISSN] 1538-7445
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / KIDINS220 protein, human; 0 / Membrane Proteins; 0 / Nerve Tissue Proteins; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
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44. Jin S, Higashihara T, Jin KS, Yoon J, Rho Y, Ahn B, Kim J, Hirao A, Ree M: Synchrotron X-ray scattering characterization of the molecular structures of star polystyrenes with varying numbers of arms. J Phys Chem B; 2010 May 20;114(19):6247-57

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchrotron X-ray scattering characterization of the molecular structures of star polystyrenes with varying numbers of arms.
  • We have synthesized well-defined multiarmed star polystyrenes, with 6, 9, 17, 33, and 57 arms, and studied their molecular shapes and structural characteristics in a good solvent (tetrahydrofuran at 25 degrees C) and in a theta (Theta) solvent (cyclohexane at 35 degrees C) by small-angle X-ray scattering (SAXS) using a synchrotron radiation source.
  • Analysis of the SAXS data provided a detailed characterization of the molecular shapes, including the contributions of the blob morphology of the arms, the radius of gyration, the paired distance distribution, the radial electron density distribution, and the Zimm-Stockmayer and Roovers g-factor, for the multiarmed star polystyrenes.
  • In particular, the molecular shapes of the star polystyrenes were found to change from a fuzzy ellipsoid, for the 6-armed polystyrene, to a fuzzy sphere, for the 57-armed polystyrene, with an increasing number of arms.
  • The ellipsoidal character of the star polystyrenes with fewer arms may originate from the extended anisotropically branched architecture at the center of the molecule.
  • The arms of the star polystyrenes were found to be more extended than those of the linear polystyrenes.
  • Furthermore, the degree of chain extension in the arms increased with the number of arms.

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  • (PMID = 20426443.001).
  • [ISSN] 1520-5207
  • [Journal-full-title] The journal of physical chemistry. B
  • [ISO-abbreviation] J Phys Chem B
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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45. Yuan YH, Wang C, Yuan Y, Hunt RH: Meta-analysis: incidence of endoscopic gastric and duodenal ulcers in placebo arms of randomized placebo-controlled NSAID trials. Aliment Pharmacol Ther; 2009 Aug;30(3):197-209
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  • [Title] Meta-analysis: incidence of endoscopic gastric and duodenal ulcers in placebo arms of randomized placebo-controlled NSAID trials.
  • AIM: To investigate the incidence of gastric and duodenal ulcers (GDU) in placebo arms in NSAID trials over the last three decades.
  • The pooled incidence of GDU in placebo arms was calculated and compared.
  • Meta-regression was used to identify risk factors related to the incidence of the placebo ulcer at the study level.
  • In total, 3.29% GDUs were reported in 36 placebo arms.
  • The incidence of GDU in placebo arms was 0, 4.20% and 3.03% in the studies from 1975-1989, 1990-1999 and 2000-2006 respectively (P > 0.05).
  • CONCLUSIONS: The incidence of GDU in placebo arms has not changed significantly over the last three decades, although has decreased in the past 10 years.
  • Studies show that previous GI events and co-therapy with low-dose aspirin/corticosteroids were associated with increasing GDU in placebo arms.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Double-Blind Method. Endoscopy. Female. Humans. Incidence. Male. Middle Aged. Randomized Controlled Trials as Topic. Risk Factors. Young Adult

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  • [CommentIn] Aliment Pharmacol Ther. 2009 Nov 1;30(9):955-7; author reply 957-60 [19807724.001]
  • (PMID = 19438429.001).
  • [ISSN] 1365-2036
  • [Journal-full-title] Alimentary pharmacology & therapeutics
  • [ISO-abbreviation] Aliment. Pharmacol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Anti-Ulcer Agents
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46. Nakajima M, Kumada K, Hatakeyama K, Noda T, Peters JM, Hirota T: The complete removal of cohesin from chromosome arms depends on separase. J Cell Sci; 2007 Dec 1;120(Pt 23):4188-96
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The complete removal of cohesin from chromosome arms depends on separase.
  • The prophase pathway, which requires phosphorylation of the cohesin subunit SA2 and a cohesin-binding protein, called Wapl, removes the bulk of cohesin from the chromosome arms in early mitosis and allows the resolution of the chromosome arms.
  • When anaphase onset is delayed by the spindle-assembly checkpoint, the complete removal of cohesin from chromosome arms but not from centromeres generates typical X- or V-shaped chromosomes.
  • Here, we found that cohesion between chromosome arms is preserved if mitosis is arrested with the proteasome inhibitor MG132.
  • This arm cohesion depends on cohesin complexes that are protected by the shugoshin protein Sgo1, which appears to be distributed on chromosome arms as well as on centromeres in early mitosis.

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  • (PMID = 18003702.001).
  • [ISSN] 0021-9533
  • [Journal-full-title] Journal of cell science
  • [ISO-abbreviation] J. Cell. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Azure Stains; 0 / Cell Cycle Proteins; 0 / Chromosomal Proteins, Non-Histone; 0 / Enzyme Inhibitors; 0 / Leupeptins; 0 / Nuclear Proteins; 0 / Proteasome Inhibitors; 0 / RNA, Small Interfering; 0 / SGOL1 protein, human; 0 / cohesins; 133407-82-6 / benzyloxycarbonylleucyl-leucyl-leucine aldehyde; EC 3.4.- / Endopeptidases; EC 3.4.22.49 / ESPL1 protein, human; EC 3.4.22.49 / Separase; SH1WY3R615 / Nocodazole
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47. Billings T, Wu JJ, Dyson S: Erythematous plaques on the face, trunk, and upper arms. Dermatol Online J; 2010;16(7):14

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  • [Title] Erythematous plaques on the face, trunk, and upper arms.
  • An 18-year-old woman presented with a one-year history of erythematous to slightly violaceous indurated papules and plaques on the face, earlobes, neck, upper arms, chest, and upper back.
  • [MeSH-major] Lupus Erythematosus, Cutaneous / diagnosis

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  • (PMID = 20673542.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 4QWG6N8QKH / Hydroxychloroquine
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48. Ackland DC, Pak P, Richardson M, Pandy MG: Moment arms of the muscles crossing the anatomical shoulder. J Anat; 2008 Oct;213(4):383-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Moment arms of the muscles crossing the anatomical shoulder.
  • The objective of the present study was to determine the instantaneous moment arms of 18 major muscle sub-regions crossing the glenohumeral joint during coronal-plane abduction and sagittal-plane flexion.
  • The tendon-excursion method was used to measure instantaneous muscle moment arms in eight entire upper-extremity cadaver specimens.
  • Significant differences in moment arms were reported across sub-regions of the deltoid, pectoralis major, latissimus dorsi, subscapularis, infraspinatus and supraspinatus (P < 0.01).
  • In flexion, the superior pectoralis major (clavicular fibers), anterior and posterior supraspinatus, and anterior deltoid were the most effective flexors, whereas the teres major and posterior deltoid had the largest extensor moment arms.

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  • (PMID = 18691376.001).
  • [ISSN] 1469-7580
  • [Journal-full-title] Journal of anatomy
  • [ISO-abbreviation] J. Anat.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2644775
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49. Wang H, Denton AR: Effective electrostatic interactions in solutions of polyelectrolyte stars with rigid rodlike arms. J Chem Phys; 2005 Dec 22;123(24):244901
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effective electrostatic interactions in solutions of polyelectrolyte stars with rigid rodlike arms.
  • In solutions of star-branched polyelectrolytes, electrostatic interactions between charged arms on neighboring stars can compete with intrastar interactions and rotational entropy to induce anisotropy in the orientational distribution of arms.
  • We explore the influence of arm orientational anisotropy on effective star-star interactions for model stars comprising rigid rodlike arms with evenly spaced charged monomers interacting via an effective screened-Coulomb (Yukawa) potential.
  • For comparison, a torque balance analysis is performed to obtain the configuration and energy of the ground state, in which the torque vanishes on each arm of the two-star system.
  • As two stars begin to overlap, the forward arms are pushed back by interstar arm-arm repulsion, but partially interdigitate due to rotational entropy.
  • At center-center separations approaching complete overlap, the arms relax to an isotropic distribution.
  • For overlapping stars, the effective pair interactions in the simple rigid-arm-Yukawa model agree closely with simulations of a molecular model that includes flexible arms and explicit counterions [A.

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  • (PMID = 16396567.001).
  • [ISSN] 0021-9606
  • [Journal-full-title] The Journal of chemical physics
  • [ISO-abbreviation] J Chem Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. Broome MR, Matthiasson P, Fusar-Poli P, Woolley JB, Johns LC, Tabraham P, Bramon E, Valmaggia L, Williams SC, Brammer MJ, Chitnis X, McGuire PK: Neural correlates of movement generation in the 'at-risk mental state'. Acta Psychiatr Scand; 2010 Oct;122(4):295-301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neural correlates of movement generation in the 'at-risk mental state'.
  • OBJECTIVE: People with 'prodromal' symptoms have a very high risk of developing psychosis.
  • We examined the neurocognitive basis of this vulnerability by using functional MRI to study subjects with an at-risk mental state (ARMS) while they performed a random movement generation task.
  • METHOD: Cross-sectional comparison of individuals with an ARMS (n = 17), patients with first episode schizophreniform psychosis (n = 10) and healthy volunteers (n = 15).
  • RESULTS: During random movement generation, the ARMS group showed less activation in the left inferior parietal cortex than controls, but greater activation than in the first episode group.
  • CONCLUSION: The ARMS is associated with abnormalities of regional brain function that are qualitatively similar to those in patients who have recently presented with psychosis but less severe.
  • [MeSH-minor] Adult. Antipsychotic Agents / therapeutic use. Causality. Cross-Sectional Studies. Disease Susceptibility. Humans. Magnetic Resonance Imaging. Mental Health. Motor Activity. Schizophrenia / diagnosis. Schizophrenia / epidemiology. Schizophrenia / physiopathology. Schizophrenia / therapy. Task Performance and Analysis

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  • (PMID = 20064129.001).
  • [ISSN] 1600-0447
  • [Journal-full-title] Acta psychiatrica Scandinavica
  • [ISO-abbreviation] Acta Psychiatr Scand
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0901310; United Kingdom / Department of Health / / PDA/02/06/016; United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antipsychotic Agents
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51. Barr M Jr: The long arms of anencephaly: A refutation. Birth Defects Res A Clin Mol Teratol; 2009 Aug;85(8):710-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The long arms of anencephaly: A refutation.
  • A paper published in 1925 reported that human fetuses with anencephaly have arms that are longer than normal.
  • This finding was accepted as true through the early 1990s.
  • An analysis of body dimensions done in 1996 and enlarged and updated here shows that the arms of human fetuses with anencephaly are appropriate for gestational age and normal in proportion to their leg lengths.
  • [MeSH-minor] Female. Fetus / abnormalities. Fetus / anatomy & histology. Fetus / embryology. Humans. Leg / abnormalities. Leg / embryology. Leg / ultrasonography. Pregnancy. Prenatal Diagnosis

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19441097.001).
  • [ISSN] 1542-0760
  • [Journal-full-title] Birth defects research. Part A, Clinical and molecular teratology
  • [ISO-abbreviation] Birth Defects Res. Part A Clin. Mol. Teratol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Sandu L, Topala F, Porojan S: Stress distribution in retentive arms of combination clasps used on premolars. J Appl Biomater Biomech; 2010 May-Aug;8(2):76-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stress distribution in retentive arms of combination clasps used on premolars.
  • INTRODUCTION: Stresses resulting from cast clasp arms during insertion and the removal of removable partial dentures are the main causes of deformations or fractures.
  • OBJECTIVE: Retentive clasp arms used for premolars were investigated through the reverse engineering approach.
  • MATERIAL AND METHODS: Purposely designed experimental three-dimensional (3D) models of the clasp arms were constructed on the buccal surface of an upper first premolar, to be used for structural simulations.
  • 3D teeth models obtained after laser scanning were used as a support for retentive clasp arms modeling.
  • Parameters of the clasp arms like length, thickness and cross-section were considered for the simulation of stainless steel wires.
  • This model was a useful tool in designing stainless steel clasp arms of different thickness and cross-section.
  • CONCLUSIONS: This in vitro study demonstrated that the reverse engineering approach and structural analyses provide a powerful tool for designing clasps and visualizing fracture risk areas and for choosing the adequate cross-section for each case.
  • Within the limitations of this study, it was suggested that, on premolars, the biomechanical performance of half-round cross-sections for the retentive arms may be higher than round sections of clasp arms showing similar mechanical stiffness.

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  • (PMID = 20740469.001).
  • [ISSN] 1722-6899
  • [Journal-full-title] Journal of applied biomaterials & biomechanics : JABB
  • [ISO-abbreviation] J Appl Biomater Biomech
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
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53. Paschalis V, Nikolaidis MG, Giakas G, Jamurtas AZ, Koutedakis Y: Differences between arms and legs on position sense and joint reaction angle. J Strength Cond Res; 2009 Sep;23(6):1652-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differences between arms and legs on position sense and joint reaction angle.
  • The purpose of the present investigation was to compare the arms and legs in relation to position sense and joint reaction angle.
  • The results of position sense showed that the arms were placed closer to the reference angle compared with the legs (1.3 degrees vs. 3.1 degrees on average for 3 angles, respectively; p < 0.05).
  • The arms also exhibited faster reaction angle to release compared with legs (3.4 degrees vs. 6.3 degrees on average for 3 angles, respectively; p < 0.05).
  • In conclusion, the ability of arms to perform more accurate and faster movements than legs may mainly be attributed to the higher number of muscle spindles and the lower innervation ratio of arms.
  • An imbalance of the determined relationship between arms and legs in position sense and reaction angle may indicate a neuromuscular disturbance.

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  • (PMID = 19675501.001).
  • [ISSN] 1533-4287
  • [Journal-full-title] Journal of strength and conditioning research
  • [ISO-abbreviation] J Strength Cond Res
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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54. Gorea RK: Impact of proliferation of small arms and light weapons in south Asia. Med Confl Surviv; 2006 Jul-Sep;22(3):199-206
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of proliferation of small arms and light weapons in south Asia.
  • Small arms and light weapons (SALW) cause much death and injury around the world, through war, homicide and suicide.

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  • (PMID = 16961121.001).
  • [ISSN] 1362-3699
  • [Journal-full-title] Medicine, conflict, and survival
  • [ISO-abbreviation] Med Confl Surviv
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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55. Luo S, Chen Y, Lai KO, Arévalo JC, Froehner SC, Adams ME, Chao MV, Ip NY: {alpha}-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner. J Cell Biol; 2005 Jun 6;169(5):813-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] {alpha}-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner.
  • In this study, we show that ankyrin repeat-rich membrane spanning (ARMS; also known as a kinase D-interacting substrate of 220 kD), a substrate for ephrin and neurotrophin receptors, was expressed in developing muscle and was concentrated at the neuromuscular junction (NMJ).
  • Using yeast two-hybrid screening, we identified a PDZ (PSD-95, Dlg, ZO-1) domain protein, alpha-syntrophin, as an ARMS-interacting protein in muscle.
  • Overexpression of alpha-syntrophin induced ARMS clustering in a PDZ domain-dependent manner.
  • Coexpression of ARMS enhanced EphA4 signaling, which was further augmented by the presence of alpha-syntrophin.
  • Moreover, the ephrin-A1-induced tyrosine phosphorylation of EphA4 was reduced in C2C12 myotubes after the blockade of ARMS and alpha-syntrophin expression by RNA interference.
  • Finally, alpha-syntrophin-null mice exhibited a disrupted localization of ARMS and EphA4 at the NMJ and a reduced expression of ARMS in muscle.
  • Altogether, our findings suggest that ARMS may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EphA4.

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  • (PMID = 15939763.001).
  • [ISSN] 0021-9525
  • [Journal-full-title] The Journal of cell biology
  • [ISO-abbreviation] J. Cell Biol.
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / P01 HD023315; United States / NINDS NIH HHS / NS / R01 NS021072; United States / NINDS NIH HHS / NS / R56 NS021072
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium-Binding Proteins; 0 / Ephrins; 0 / Kidins220 protein, rat; 0 / Membrane Proteins; 0 / Muscle Proteins; 0 / Phosphoproteins; 0 / syntrophin alpha1; EC 2.7.10.1 / Receptor, EphA4
  • [Other-IDs] NLM/ PMC2171611
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56. Gatti CJ, Dickerson CR, Chadwick EK, Mell AG, Hughes RE: Comparison of model-predicted and measured moment arms for the rotator cuff muscles. Clin Biomech (Bristol, Avon); 2007 Jul;22(6):639-44
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of model-predicted and measured moment arms for the rotator cuff muscles.
  • BACKGROUND: The ability of mathematical models of the shoulder to accurately replicate physiological muscle moment arms is unknown.
  • The purpose of this study was to compare model-predicted and experimentally measured moment arms for the rotator cuff muscles during arm elevation.
  • METHODS: Moment arms obtained from six mathematical models and seven experimental studies were compared for the supraspinatus, infraspinatus, teres minor, and subscapularis for elevation in the scapular plane.
  • RESULTS: All of the included models generated moment arms that generally fell within the range of experimentally measured data.
  • INTERPRETATION: The quantitative agreement between model-predicted and experimentally measured moment arms supports the use of the included models for biomechanical shoulder analyses.

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  • (PMID = 17395346.001).
  • [ISSN] 0268-0033
  • [Journal-full-title] Clinical biomechanics (Bristol, Avon)
  • [ISO-abbreviation] Clin Biomech (Bristol, Avon)
  • [Language] ENG
  • [Grant] United States / NIAMS NIH HHS / AR / AR048540-03; United States / NIAMS NIH HHS / AR / R01 AR048540; United States / NIAMS NIH HHS / AR / AR048540; United States / NIAMS NIH HHS / AR / R01 AR048540-03
  • [Publication-type] Comparative Study; Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS25746; NLM/ PMC1950345
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57. Smith NC, Payne RC, Jespers KJ, Wilson AM: Muscle moment arms of pelvic limb muscles of the ostrich (Struthio camelus). J Anat; 2007 Sep;211(3):313-24

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Muscle moment arms of pelvic limb muscles of the ostrich (Struthio camelus).
  • Muscle moment arms were measured for major muscles of the pelvic limb of the ostrich (Struthio camelus) in order to assess specific functional behaviour and to apply this to locomotor performance.
  • The tendon travel technique was used to measure moment arms of 21 muscles at the hip, knee, ankle and metatarsophalangeal joints throughout the ranges of motion observed during level running.
  • Six of the 21 muscles measured were found to have moment arms that did not change with joint angle, whilst the remainder all demonstrated angle-dependent changes for at least one of the joints crossed.
  • Moment arm lengths tended to be longest for the large proximal muscles, whilst the largest relative changes were found for the moment arms of the distal muscles.
  • For muscles where moment arm varied with joint angle: all hip muscles were found to have increasing moment arms with extension of the joint, knee flexors were found to have moment arms that increased with extension, knee extensor moment arms were found to increase with flexion and ankle extensor moment arms increased with extension.

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  • (PMID = 17608640.001).
  • [ISSN] 0021-8782
  • [Journal-full-title] Journal of anatomy
  • [ISO-abbreviation] J. Anat.
  • [Language] eng
  • [Grant] United Kingdom / Biotechnology and Biological Sciences Research Council / / BB/E013244/1
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2375818
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58. Gunderina LI, Kinadze II, Istomina AG, Gusev VD, Miroshnichenko LA: [Divergence patterns of banding sequences in different polytene chromosome arms reflect relatively independent evolution of different genome components]. Genetika; 2005 Apr;41(4):549-58

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Divergence patterns of banding sequences in different polytene chromosome arms reflect relatively independent evolution of different genome components].
  • Divergence patterns of the banding sequences from the chromosomal arms A, C, D, E, and F were compared in 63 species of the genus Chironomus.
  • Evaluation of the number of breakpoints between the pairs of inverted banding sequences and the analysis of the lengths of the conserved segments in the chromosomal arms in the chironomid species examined showed that different arms evolved relatively independently and at different rates.

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  • (PMID = 15909915.001).
  • [ISSN] 0016-6758
  • [Journal-full-title] Genetika
  • [ISO-abbreviation] Genetika
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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59. Brodie ED 3rd, Feldman CR, Hanifin CT, Motychak JE, Mulcahy DG, Williams BL, Brodie ED Jr: Parallel arms races between garter snakes and newts involving tetrodotoxin as the phenotypic interface of coevolution. J Chem Ecol; 2005 Feb;31(2):343-56
Hazardous Substances Data Bank. TETRODOTOXIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parallel arms races between garter snakes and newts involving tetrodotoxin as the phenotypic interface of coevolution.
  • Parallel "arms races" involving the same or similar phenotypic interfaces allow inference about selective forces driving coevolution, as well as the importance of phylogenetic and phenotypic constraints in coevolution.
  • Here, we report the existence of apparent parallel arms races between species pairs of garter snakes and their toxic newt prey that indicate independent evolutionary origins of a key phenotype in the interface.

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  • (PMID = 15856788.001).
  • [ISSN] 0098-0331
  • [Journal-full-title] Journal of chemical ecology
  • [ISO-abbreviation] J. Chem. Ecol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 4368-28-9 / Tetrodotoxin
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60. Bilgic H, Cho S, Garvin DF, Muehlbauer GJ: Mapping barley genes to chromosome arms by transcript profiling of wheat-barley ditelosomic chromosome addition lines. Genome; 2007 Oct;50(10):898-906
SciCrunch. ArrayExpress: Data: Microarray .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mapping barley genes to chromosome arms by transcript profiling of wheat-barley ditelosomic chromosome addition lines.
  • We mapped 1257 barley genes to chromosome arms 1HS, 2HS, 2HL, 3HS, 3HL, 4HS, 4HL, 5HS, 5HL, 7HS, and 7HL based on their transcript levels in the ditelosomic addition lines.
  • The number of genes assigned to individual chromosome arms ranged from 24 to 197.
  • We found our physical mapping of barley genes to chromosome arms to be consistent with our previous physical mapping to whole chromosomes.
  • In silico comparative mapping of barley genes assigned to chromosome arms revealed that the average genomic synteny to wheat and rice chromosome arms was 63.2% and 65.5%, respectively.

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  • (PMID = 18059553.001).
  • [ISSN] 0831-2796
  • [Journal-full-title] Genome
  • [ISO-abbreviation] Genome
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Genetic Markers
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61. Fichtelberg A: Applying the rules of just war theory to engineers in the arms industry. Sci Eng Ethics; 2006 Oct;12(4):685-700
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Applying the rules of just war theory to engineers in the arms industry.
  • Given the close relationship between the modern arms industry and the military, engineers and other professionals who work in the arms industry should be held accountable to the principles of just war theory.
  • They are morally responsible both for choosing the companies that employ them (and to whom these companies sell arms) and a well as what types of arms they develop.

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  • [Cites] Sci Eng Ethics. 2004 Oct;10(4):667-92 [15586727.001]
  • (PMID = 17199144.001).
  • [ISSN] 1353-3452
  • [Journal-full-title] Science and engineering ethics
  • [ISO-abbreviation] Sci Eng Ethics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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62. Yamashita T, Uno T, Ishikawa Y: Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms. Bioorg Med Chem; 2005 Apr 1;13(7):2423-30
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms.
  • We synthesized novel quadruplex-interacting porphyrins with cationic pyridinium and trimethylammonium arms at para- or meta-position of all phenyl groups of tetratolyl porphyrin.
  • The cationic side arms played a key role in the stabilization of the quadruplex structure.

  • Hazardous Substances Data Bank. GUANINE .
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  • (PMID = 15755644.001).
  • [ISSN] 0968-0896
  • [Journal-full-title] Bioorganic & medicinal chemistry
  • [ISO-abbreviation] Bioorg. Med. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cations; 0 / Porphyrins; 5Z93L87A1R / Guanine; 9007-49-2 / DNA
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63. Broome MR, Fusar-Poli P, Matthiasson P, Woolley JB, Valmaggia L, Johns LC, Tabraham P, Bramon E, Williams SC, Brammer MJ, Chitnis X, Zelaya F, McGuire PK: Neural correlates of visuospatial working memory in the 'at-risk mental state'. Psychol Med; 2010 Dec;40(12):1987-99
MedlinePlus Health Information. consumer health - Schizophrenia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neural correlates of visuospatial working memory in the 'at-risk mental state'.
  • BACKGROUND: Impaired spatial working memory (SWM) is a robust feature of schizophrenia and has been linked to the risk of developing psychosis in people with an at-risk mental state (ARMS).
  • We used functional magnetic resonance imaging (fMRI) to examine the neural substrate of SWM in the ARMS and in patients who had just developed schizophrenia.
  • METHOD: fMRI was used to study 17 patients with an ARMS, 10 patients with a first episode of psychosis and 15 age-matched healthy comparison subjects.
  • Significant between-group differences in activation were evident in a cluster spanning the medial frontal cortex and right precuneus, with the ARMS groups showing less activation than controls but greater activation than first-episode psychosis (FEP) patients.
  • However, there was a significant group difference in the response of the right precuneus across repeated trials, with an attenuation of activation in controls but increased activation in FEP and little change in the ARMS.

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  • (PMID = 20214840.001).
  • [ISSN] 1469-8978
  • [Journal-full-title] Psychological medicine
  • [ISO-abbreviation] Psychol Med
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0901310; United Kingdom / Department of Health / / PDA/02/06/016
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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64. Schober H, Kalck V, Vega-Palas MA, Van Houwe G, Sage D, Unser M, Gartenberg MR, Gasser SM: Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast. Genome Res; 2008 Feb;18(2):261-71
Saccharomyces Genome Database. Saccharomyces Genome Database .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast.
  • To test whether unique sequence elements, arm length, or chromosome territories influence juxtaposition, we reciprocally swapped terminal domains or entire chromosomal arms from one chromosome to another.
  • By manipulating the length and sequence composition of the right arm of chr 5, we confirm that contact between telomeres on opposite chromatid arms of equal length is favored.
  • These results can be explained by the polarized Rabl arrangement of yeast centromeres and telomeres, which promote to telomere pairing by allowing contact between chromosome arms of equal length in anaphase.

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  • (PMID = 18096749.001).
  • [ISSN] 1088-9051
  • [Journal-full-title] Genome research
  • [ISO-abbreviation] Genome Res.
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / R01 GM051402
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2203624
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65. Valmaggia LR, Freeman D, Green C, Garety P, Swapp D, Antley A, Prescott C, Fowler D, Kuipers E, Bebbington P, Slater M, Broome M, McGuire PK: Virtual reality and paranoid ideations in people with an 'at-risk mental state' for psychosis. Br J Psychiatry Suppl; 2007 Dec;51:s63-8
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  • [Title] Virtual reality and paranoid ideations in people with an 'at-risk mental state' for psychosis.
  • AIMS: To establish the feasibility and safety of using virtual reality methodology in people with an at-risk mental state and to investigate the applicability of a cognitive model of paranoia to this group.
  • METHOD: Twenty-one participants with an at-risk mental state were assessed before and after entering a virtual reality environment depicting the inside of an underground train.
  • Individuals attributed mental states to virtual reality characters including hostile intent.
  • CONCLUSIONS: Virtual reality is an acceptable experimental technique for use with individuals with at-risk mental states.

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  • (PMID = 18055940.001).
  • [ISSN] 0960-5371
  • [Journal-full-title] The British journal of psychiatry. Supplement
  • [ISO-abbreviation] Br J Psychiatry Suppl
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / / 062452
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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66. Brouhard GJ, Hunt AJ: Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitro. Proc Natl Acad Sci U S A; 2005 Sep 27;102(39):13903-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitro.
  • During mitosis, "polar ejection forces" (PEFs) are hypothesized to direct prometaphase chromosome movements by pushing chromosome arms toward the spindle equator.
  • PEFs are postulated to be caused by (i) plus-end-directed microtubule (MT)-based motor proteins on the chromosome arms, namely chromokinesins, and (ii) the polymerization of spindle MTs into the chromosome.
  • In this study, we employ optical tweezers to bring about the lateral interaction between chromosome arms and MTs in vitro to directly measure the speed and force of the PEFs developed on chromosome arms.

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  • (PMID = 16174726.001).
  • [ISSN] 0027-8424
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies; 0 / DNA-Binding Proteins; 0 / Nuclear Proteins; 0 / chromokinesin; 8L70Q75FXE / Adenosine Triphosphate; EC 3.6.1.- / Kinesin
  • [Other-IDs] NLM/ PMC1236563
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67. Sumina MV, Azizova TV, Vlasenko EV, Osovets SV, Gergenreĭder SN, Grigor'eva ES, Krupenina LN: [Chronic morbidity parameters in personel engaged into processing and utilization of arms and military equipment]. Med Tr Prom Ekol; 2009;(10):13-8
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  • [Title] [Chronic morbidity parameters in personel engaged into processing and utilization of arms and military equipment].
  • Analysis of chronic morbidity parameters in workers engaged into processing and utilization of arms and military equipment did not reveal any case of occupational radiation disease over 30 years of medical observation.
  • [MeSH-minor] Adult. Chronic Disease. Female. Humans. Male. Middle Aged. Morbidity / trends. Russia / epidemiology

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  • (PMID = 19943527.001).
  • [ISSN] 1026-9428
  • [Journal-full-title] Meditsina truda i promyshlennaia ekologiia
  • [ISO-abbreviation] Med Tr Prom Ekol
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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68. Cortés RY, Arévalo JC, Magby JP, Chao MV, Plummer MR: Developmental and activity-dependent regulation of ARMS/Kidins220 in cultured rat hippocampal neurons. Dev Neurobiol; 2007 Nov;67(13):1687-98
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Developmental and activity-dependent regulation of ARMS/Kidins220 in cultured rat hippocampal neurons.
  • A unique downstream protein is the Ankyrin-Repeat Rich Membrane Spanning (ARMS)/Kinase D-interacting substrate-220 kDa (Kidins220), a very abundant scaffold protein in the hippocampus.
  • To determine the roles of ARMS/Kidins220 in hippocampal neurons, we have analyzed the effects of synaptic activity upon the regulation and distribution of ARMS/Kidins220.
  • At early times in vitro (<7 DIV), synaptic activity was low and ARMS/Kidins220 levels were high.
  • As synaptic activity and markers for synapse maturation, such as PSD-95, increased, ARMS/Kidins220 significantly decreased to a plateau by later times in vitro (>12 DIV).
  • Immunocytochemistry showed ARMS/Kidins220 to be concentrated at the tips of growing processes in immature cultures, and more diffusely distributed in older cultures.
  • To examine the apparent inverse relationship between activity and ARMS/Kidins220 levels, neuronal firing was manipulated pharmacologically.
  • Chronic exposure to TTX increased ARMS/Kidins220 levels, whereas bicuculline caused the opposite effect.
  • Moreover, using shRNA to decrease ARMS/Kidins220 levels produced a corresponding increase in synaptic activity.
  • We find that ARMS/Kidins220 may function in neuronal development as an indicator and potentially as a homeostatic regulator of overall synaptic strength in hippocampal neurons.
  • [MeSH-major] Hippocampus / embryology. Membrane Proteins / metabolism. Neuronal Plasticity / physiology. Neurons / metabolism. Phosphoproteins / metabolism. Synapses / metabolism

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  • [Copyright] 2007 Wiley Periodicals, Inc
  • (PMID = 17587220.001).
  • [ISSN] 1932-8451
  • [Journal-full-title] Developmental neurobiology
  • [ISO-abbreviation] Dev Neurobiol
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / HD023315; United States / NINDS NIH HHS / NS / NS21072; United States / NINDS NIH HHS / NS / NS41310
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Kidins220 protein, rat; 0 / Membrane Proteins; 0 / Phosphoproteins
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69. Faria CD, Teixeira-Salmela LF, Goulart FR, Gomes PF: Comparisons of electromyographic activity of scapular muscles between elevation and lowering of the arms. Physiother Theory Pract; 2008 Sep-Oct;24(5):360-71

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparisons of electromyographic activity of scapular muscles between elevation and lowering of the arms.
  • The aim of this study was to compare the electromyographic (EMG) activity levels of the serratus anterior, upper, middle, and lower trapezius muscles between elevation and lowering of the arms with 10 healthy subjects.
  • Significant differences were found between the elevation and the lowering of the arms for all muscles (p<or=0.001).
  • In addition, significant differences were found between phases for all muscles during elevation (p<or=0.001) and lowering of the arms (0.001<p<0.01).

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  • (PMID = 18821442.001).
  • [ISSN] 1532-5040
  • [Journal-full-title] Physiotherapy theory and practice
  • [ISO-abbreviation] Physiother Theory Pract
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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70. Gal-Mark N, Schwartz S, Ast G: Alternative splicing of Alu exons--two arms are better than one. Nucleic Acids Res; 2008 Apr;36(6):2012-23
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  • [Title] Alternative splicing of Alu exons--two arms are better than one.
  • They are composed of two related but distinct monomers, left and right arms.
  • Most exonizations occur in right arms of antisense Alu elements, and are alternatively spliced.
  • Although the two arms are highly similar, the left arm is characterized by weaker splicing signals and lower exonic splicing regulatory (ESR) densities.

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  • (PMID = 18276646.001).
  • [ISSN] 1362-4962
  • [Journal-full-title] Nucleic acids research
  • [ISO-abbreviation] Nucleic Acids Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2330237
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71. Mayrovitz HN, Sims N, Brown-Cross D, Humen S, Cohen P, Kleinman-Barnett C: Transcutaneous oxygen tension in arms of women with unilateral postmastectomy lymphedema. Lymphology; 2005 Jun;38(2):81-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transcutaneous oxygen tension in arms of women with unilateral postmastectomy lymphedema.
  • Previous reports suggest that skin blood flow is reduced in arms of women with lymphedema due to breast cancer treatment.
  • TcPO2 was measured in fibrotic areas of affected arms and in corresponding sites on non-affected arms of 15 women with unilateral arm lymphedema before and after CDP therapy sequences.
  • TcPO2 did not differ between arms initially and did not change with treatment, being 60.1 +/- 8.8 mmHg at the start and 61.8 +/- 9.2 mmHg at the end of treatment.
  • Thus, despite significant amounts of initial edema, TcPO2 was not initially less in affected arms nor was it changed by therapy that improved both edema and fibrosis.

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  • (PMID = 16184817.001).
  • [ISSN] 0024-7766
  • [Journal-full-title] Lymphology
  • [ISO-abbreviation] Lymphology
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] S88TT14065 / Oxygen
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72. Gray S, Watts S, Debicki D, Hore J: Comparison of kinematics in skilled and unskilled arms of the same recreational baseball players. J Sports Sci; 2006 Nov;24(11):1183-94

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of kinematics in skilled and unskilled arms of the same recreational baseball players.
  • Arm segment angular kinematics in three dimensions at 1000 Hz were recorded with the search-coil technique from the arms of eight individuals who on one occasion threw with their skilled right arm and on another with their unskilled left arm.
  • Compared with their unskilled arm, the skilled arm had: a larger angular deceleration of the upper arm in space in the forward horizontal direction; a larger shoulder internal rotation velocity at ball release (unskilled arms had a negative velocity); a period of elbow extension deceleration before ball release; and an increase in wrist velocity with an increase in ball speed.
  • It is suggested that some of these differences in arm kinematics occur because of differences between the skilled and unskilled arms in their ability to control interaction torques (the passive torque at one joint due to motion at adjacent joints).

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  • (PMID = 17175616.001).
  • [ISSN] 0264-0414
  • [Journal-full-title] Journal of sports sciences
  • [ISO-abbreviation] J Sports Sci
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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73. Schneiders FI, Maertens B, Böse K, Li Y, Brunken WJ, Paulsson M, Smyth N, Koch M: Binding of netrin-4 to laminin short arms regulates basement membrane assembly. J Biol Chem; 2007 Aug 17;282(33):23750-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Binding of netrin-4 to laminin short arms regulates basement membrane assembly.
  • All netrins share structural homology to the laminin N-terminal domains and the laminin epidermal growth factor-like domains of laminin short arms.
  • Here we demonstrate that netrin-4 is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms.
  • In contrast to netrin-4, other members of the netrin family do not bind to these laminin short arms.
  • [MeSH-major] Basement Membrane / cytology. Laminin / metabolism. Nerve Growth Factors / metabolism
  • [MeSH-minor] Animals. Cells, Cultured. Mice. Morphogenesis. Mutation. Protein Binding. Protein Structure, Tertiary. Salivary Glands / cytology

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  • (PMID = 17588941.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lamc3 protein, mouse; 0 / Laminin; 0 / Nerve Growth Factors; 0 / Ntn4 protein, mouse; 0 / laminin gamma 1
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74. Maor R, Shirasu K: The arms race continues: battle strategies between plants and fungal pathogens. Curr Opin Microbiol; 2005 Aug;8(4):399-404
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  • [Title] The arms race continues: battle strategies between plants and fungal pathogens.
  • The arms race between plants and fungal pathogens is fascinatingly varied, and what might be elicited as a plant defence mechanism against a pathogen could promote or enhance the virulence of other pathogens.
  • Several lines of evidence indicate a co-evolutionary arms race in which both plants and fungi can respond to changes that occur in their opponents.

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  • (PMID = 15996507.001).
  • [ISSN] 1369-5274
  • [Journal-full-title] Current opinion in microbiology
  • [ISO-abbreviation] Curr. Opin. Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antifungal Agents; 0 / Glucans; 0 / Plant Extracts; 0 / Plant Growth Regulators; 0 / Sesquiterpenes; 0 / Terpenes; 37297-20-4 / phytoalexins; 9064-51-1 / callose
  • [Number-of-references] 43
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75. Ackland DC, Roshan-Zamir S, Richardson M, Pandy MG: Moment arms of the shoulder musculature after reverse total shoulder arthroplasty. J Bone Joint Surg Am; 2010 May;92(5):1221-30
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  • [Title] Moment arms of the shoulder musculature after reverse total shoulder arthroplasty.
  • (1) to measure the instantaneous moment arms of thirteen subregions of major muscles spanning the glenohumeral joint during abduction and flexion of the shoulder after reverse total shoulder arthroplasty and (2) to compare these data with the muscle moment arms previously measured preoperatively in the anatomical shoulders.
  • The specimens were mounted onto a dynamic testing apparatus, and the instantaneous abductor/adductor and flexor/extensor moment arms of subregions of the deltoid, latissimus dorsi, pectoralis major, teres major, and subscapularis muscles (a total of thirteen subregions) were measured with use of the tendon excursion method.
  • These muscle moment arms were compared with those measured preoperatively in the anatomical shoulders.
  • RESULTS: Reverse total shoulder arthroplasty resulted in significant increases in the abductor moment arms of the anterior subregion of the deltoid (mean increase = 10.4 mm; 95% confidence interval = 7.5 to 13.3 mm) and the middle subregion of the deltoid (mean increase = 15.5 mm; 95% confidence interval = 10.8 to 20.3 mm) as well as recruitment of the posterior subregion of the deltoid as an abductor.
  • The adductor and extensor moment arms of the teres major, latissimus dorsi subregions, and inferior and middle subregions of the pectoralis major increased substantially after the arthroplasty.
  • CONCLUSIONS: Reverse total shoulder arthroplasty increases the moment arms of the major abductors, flexors, adductors, and extensors of the glenohumeral joint, thereby reducing muscle effort during common tasks such as lifting and pushing.

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  • (PMID = 20439669.001).
  • [ISSN] 1535-1386
  • [Journal-full-title] The Journal of bone and joint surgery. American volume
  • [ISO-abbreviation] J Bone Joint Surg Am
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Wu JZ, An KN, Cutlip RG, Andrew ME, Dong RG: Modeling of the muscle/tendon excursions and moment arms in the thumb using the commercial software anybody. J Biomech; 2009 Feb 9;42(3):383-8
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  • [Title] Modeling of the muscle/tendon excursions and moment arms in the thumb using the commercial software anybody.
  • A biomechanical model of a thumb would be useful for exploring the mechanical loadings in the musculoskeletal system, which cannot be measured in vivo.
  • The theoretically calculated moment arms of the tendons are compared with the corresponding experimental data by Smutz et al. [1998.
  • The predicted muscle moment arms of the majority of the muscle/tendon units agree well with the experimental data in the entire range of motion.
  • Close to the end of the motion range, the predicted moment arms of several muscles (i.e., ADPt and ADPo (transverse and oblique heads of the adductor pollicis, respectively) muscles for CMC abduction/adduction and ADPt and FPB (flexor pollicis brevis) muscle for MP extension/flexion) deviate from the experimental data.

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  • (PMID = 19124127.001).
  • [ISSN] 0021-9290
  • [Journal-full-title] Journal of biomechanics
  • [ISO-abbreviation] J Biomech
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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77. Channon AJ, Crompton RH, Günther MM, Vereecke EE: Muscle moment arms of the gibbon hind limb: implications for hylobatid locomotion. J Anat; 2010 Apr;216(4):446-62

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  • [Title] Muscle moment arms of the gibbon hind limb: implications for hylobatid locomotion.
  • Hence, larger muscle moment arms generate larger joint torques and forces at the point of application.
  • The moment arms of a number of gibbon hind limb muscles were measured on four cadaveric specimens (one Hylobates lar, one H. moloch and two H. syndactylus).
  • The data demonstrated a functional differentiation between voluminous muscles with short fascicles having small muscle moment arms and muscles with longer fascicles and comparatively smaller physiological cross-sectional area having longer muscle moment arms.

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  • (PMID = 20447251.001).
  • [ISSN] 1469-7580
  • [Journal-full-title] Journal of anatomy
  • [ISO-abbreviation] J. Anat.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
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78. Wang X, Liu X, Possoz C, Sherratt DJ: The two Escherichia coli chromosome arms locate to separate cell halves. Genes Dev; 2006 Jul 1;20(13):1727-31
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  • [Title] The two Escherichia coli chromosome arms locate to separate cell halves.
  • DNA replication divides the circular Escherichia coli chromosome into equal arms (replichores).

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  • (PMID = 16818605.001).
  • [ISSN] 0890-9369
  • [Journal-full-title] Genes & development
  • [ISO-abbreviation] Genes Dev.
  • [Language] ENG
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1522069
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79. Konstantaki M, Winter E, Swaine I: Effects of arms-only swimming training on performance, movement economy, and aerobic power. Int J Sports Physiol Perform; 2008 Sep;3(3):294-304
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  • [Title] Effects of arms-only swimming training on performance, movement economy, and aerobic power.
  • Few studies have assessed the effects of arm training on arm power and swimming performance, yet there have not been any investigations on the effects of arms-only swimming training on swimming performance and physiological responses to arm exercise.
  • PURPOSE: To investigate the changes in arms-only and full-stroke swimming performance, movement economy and aerobic power after an arms-only swimming training program.
  • For six weeks ES performed arms-only freestyle swimming exercises for 20% of their weekly training distance three times per week, whereas CS performed their usual swimming training.
  • Before and after the training program, both groups performed a) two time trials, 186 m using arms-only (186ARMS) and 372 m using full-stroke (372FULL) freestyle swimming, and b) an incremental arm-pulling exercise test.
  • CONCLUSION: Arms-only swimming training at 20% of the weekly training distance is an effective method to improve arm conditioning during the preparatory phase of the annual training cycle.

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  • (PMID = 19211942.001).
  • [ISSN] 1555-0265
  • [Journal-full-title] International journal of sports physiology and performance
  • [ISO-abbreviation] Int J Sports Physiol Perform
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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80. Liu X, Carroll CB, Wang SY, Zajicek J, Bain PG: Quantifying drug-induced dyskinesias in the arms using digitised spiral-drawing tasks. J Neurosci Methods; 2005 May 15;144(1):47-52
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  • [Title] Quantifying drug-induced dyskinesias in the arms using digitised spiral-drawing tasks.
  • In this study, we quantify the severity of drug-induced dyskinesias in the arms of Parkinson's disease (PD) patients using digitised spiral-drawing tasks.
  • Fifteen PD patients, average disease duration 14.4+/-7.4 years, were assessed 30 min after a levodopa challenge whilst performing circular and square spiral-drawing tasks.
  • The mean amplitude of dyskinetic movements was compared between arms and tasks and was correlated with clinical measures including the Bain dyskinesia scale and the total unified Parkinson's disease rating scale (UPDRS) score.
  • The results showed that there was no statistically significant difference in the amplitude of dyskinesias either between the arms or between the continuous (circular) and discrete (square) spiral drawings in this group of PD patients, but interestingly the interaction between arm and drawing pattern was significant.
  • [MeSH-minor] Adolescent. Adult. Aged. Disability Evaluation. Humans. Middle Aged. Movement / physiology. Neurologic Examination. Parkinson Disease / drug therapy. Severity of Illness Index. Spectrum Analysis

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  • (PMID = 15848238.001).
  • [ISSN] 0165-0270
  • [Journal-full-title] Journal of neuroscience methods
  • [ISO-abbreviation] J. Neurosci. Methods
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antiparkinson Agents; 46627O600J / Levodopa
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81. Higuero AM, Sánchez-Ruiloba L, Doglio LE, Portillo F, Abad-Rodríguez J, Dotti CG, Iglesias T: Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and development. J Biol Chem; 2010 Jan 8;285(2):1343-57

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  • [Title] Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and development.
  • Herein we find that the evolutionarily conserved protein Kidins220 (kinase D-interacting substrate of 220-kDa), also known as ARMS (ankyrin repeat-rich membrane spanning), a downstream effector of protein kinase D and neurotrophin and ephrin receptors, regulates the establishment of neuronal polarity and development of dendrites.
  • Kidins220/ARMS gain and loss of function experiments render severe phenotypic changes in the processes extended by hippocampal neurons in culture.
  • Although Kidins220/ARMS early overexpression hinders neuronal development, its down-regulation by RNA interference results in the appearance of multiple longer axon-like extensions as well as aberrant dendritic arbors.
  • We also find that Kidins220/ARMS interacts with tubulin and microtubule-regulating molecules whose role in neuronal morphogenesis is well established (microtubule-associated proteins 1b, 1a, and 2 and two members of the stathmin family).
  • Importantly, neurons where Kidins220/ARMS has been knocked down register changes in the phosphorylation activity of MAP1b and stathmins.
  • Altogether, our results indicate that Kidins220/ARMS is a key modulator of the activity of microtubule-regulating proteins known to actively regulate neuronal morphogenesis and suggest a mechanism by which it contributes to control neuronal development.
  • [MeSH-major] Cell Polarity / physiology. Hippocampus / metabolism. Membrane Proteins / metabolism. Microtubule-Associated Proteins / metabolism. Neurons / metabolism. Phosphoproteins / metabolism. Tubulin / metabolism

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  • (PMID = 19903810.001).
  • [ISSN] 1083-351X
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Kidins220 protein, rat; 0 / Membrane Proteins; 0 / Microtubule-Associated Proteins; 0 / Phosphoproteins; 0 / Receptors, Nerve Growth Factor; 0 / Stathmin; 0 / Tubulin; 0 / microtubule-associated protein 1B; 126195-39-9 / Stmn1 protein, rat; EC 2.7.10.- / protein kinase D; EC 2.7.11.13 / Protein Kinase C
  • [Other-IDs] NLM/ PMC2801261
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82. Watanabe Y: Sister chromatid cohesion along arms and at centromeres. Trends Genet; 2005 Jul;21(7):405-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sister chromatid cohesion along arms and at centromeres.
  • There is an obvious difference between the regulation of sister chromatid cohesion at centromeres and along chromosome arms during meiosis, because centromeric cohesion, but not arm cohesion, persists throughout anaphase of the first meiotic division.

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  • (PMID = 15946764.001).
  • [ISSN] 0168-9525
  • [Journal-full-title] Trends in genetics : TIG
  • [ISO-abbreviation] Trends Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / SGOL1 protein, human
  • [Number-of-references] 42
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83. Sumbre G, Fiorito G, Flash T, Hochner B: Neurobiology: motor control of flexible octopus arms. Nature; 2005 Feb 10;433(7026):595-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurobiology: motor control of flexible octopus arms.
  • Here we show that when the octopus uses one of its long and highly flexible arms to transfer an object from one place to another, it employs a vertebrate-like strategy, temporarily reconfiguring its arm into a stiffened, articulated, quasi-jointed structure.

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  • (PMID = 15703737.001).
  • [ISSN] 1476-4687
  • [Journal-full-title] Nature
  • [ISO-abbreviation] Nature
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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84. Chung GY: Towards identifying intervention arms in randomized controlled trials: extracting coordinating constructions. J Biomed Inform; 2009 Oct;42(5):790-800

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Towards identifying intervention arms in randomized controlled trials: extracting coordinating constructions.
  • METHODS AND RESULTS: An analysis of the types of constructs that describe the allocation of intervention arms is conducted, revealing that the compared interventions are predominantly embedded in coordinating constructions.
  • A method is developed for identifying the descriptions of the assignment of treatment arms in clinical trials, using a full sentence parser to locate coordinating constructions and a statistical classifier for labeling positive examples.
  • CONCLUSIONS: The intervention arms of a randomized controlled trials can be identified by machine extraction incorporating syntactic features derived from full sentence parsing.
  • [MeSH-minor] Humans. Information Storage and Retrieval. Unified Medical Language System

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  • (PMID = 19166975.001).
  • [ISSN] 1532-0480
  • [Journal-full-title] Journal of biomedical informatics
  • [ISO-abbreviation] J Biomed Inform
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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85. Ruckstuhl H, Krzycki J, Petrou N, Favre P, Horn T, Schmid S, Stussi E: Shoulder abduction moment arms in three clinically important positions. J Shoulder Elbow Surg; 2009 Jul-Aug;18(4):632-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Shoulder abduction moment arms in three clinically important positions.
  • The abduction moment arms of 4 shoulder muscles were calculated in clinically important positions to evaluate the best test situation for the supraspinatus based on its mechanical advantage.Moment arms of the supraspinatus, infraspinatus, and middle and anterior deltoid in 18 individuals were computed using individual magnetic resonance imaging data and a computer-assisted design tool for simulation.
  • In the Jobe position, the supraspinatus' abduction moment arm is reduced with increased internal humeral rotation.Comparing these results with the literature indicates that this new method is adequate for calculation of moment arms and may be used in any desired joint configuration.

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  • (PMID = 19655429.001).
  • [ISSN] 1532-6500
  • [Journal-full-title] Journal of shoulder and elbow surgery
  • [ISO-abbreviation] J Shoulder Elbow Surg
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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86. Qian L, Ding G, Zhou Q, Feng Z, Ding X, Gu S, Wang Y, Li X, Chu B: Molecular authentication of Dendrobium loddigesii Rolfe by Amplification Refractory Mutation System (ARMS). Planta Med; 2008 Mar;74(4):470-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular authentication of Dendrobium loddigesii Rolfe by Amplification Refractory Mutation System (ARMS).
  • In order to develop a convenient and efficient identification method for D. loddigesii, six pairs of diagnostic ARMS primers were designed based on nrDNA ITS sequences of D. loddigesii and eleven adulterants.
  • This points out the potential of ARMS analysis for authentication of D. loddigesii.
  • [MeSH-minor] DNA Primers. DNA, Intergenic. DNA, Plant. Genes, Plant. Genetic Variation. Mutation. Nucleic Acid Hybridization. Species Specificity

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  • (PMID = 18484545.001).
  • [ISSN] 0032-0943
  • [Journal-full-title] Planta medica
  • [ISO-abbreviation] Planta Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Intergenic; 0 / DNA, Plant
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87. Genson KL, Holzmueller J, Jiang C, Xu J, Gibson JD, Zubarev ER, Tsukruk VV: Langmuir-Blodgett monolayers of gold nanoparticles with amphiphilic shells from V-shaped binary polymer arms. Langmuir; 2006 Aug 1;22(16):7011-5
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Langmuir-Blodgett monolayers of gold nanoparticles with amphiphilic shells from V-shaped binary polymer arms.
  • Gold nanoparticles functionalized with amphiphilic polybutadiene-poly(ethylene glycol) (PB-PEG) V-shaped arms formed stable Langmuir monolayers at the air-water and the air-solid interfaces.
  • At these interfaces, the binary arms vertically segregated into a dense polymer corona, which surrounded the gold nanoparticles, preventing their large-scale agglomeration and keeping individual nanoparticles well-separated from each other and forming flattened, pancake nanostructures.

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  • (PMID = 16863253.001).
  • [ISSN] 0743-7463
  • [Journal-full-title] Langmuir : the ACS journal of surfaces and colloids
  • [ISO-abbreviation] Langmuir
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Calbet JA, Holmberg HC, Rosdahl H, van Hall G, Jensen-Urstad M, Saltin B: Why do arms extract less oxygen than legs during exercise? Am J Physiol Regul Integr Comp Physiol; 2005 Nov;289(5):R1448-58
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Why do arms extract less oxygen than legs during exercise?
  • To determine whether conditions for O2 utilization and O2 off-loading from the hemoglobin are different in exercising arms and legs, six cross-country skiers participated in this study.
  • The percentage of O2 extraction was always higher for the legs than for the arms.
  • During exercise, mean arm O2 extraction correlated with the P(O2) value that causes hemoglobin to be 50% saturated (P50: r = 0.93, P < 0.05), but for a given value of P50, O2 extraction was always higher in the legs than in the arms.
  • Because conditions for O2 off-loading from the hemoglobin are similar in leg and arm muscles, the observed differences in maximal arm and leg O2 extraction should be attributed to other factors, such as a higher heterogeneity in blood flow distribution, shorter mean transit time, smaller diffusing area, and larger diffusing distance, in arms than in legs.


89. Bock O, Worringham C, Thomas M: Concurrent adaptations of left and right arms to opposite visual distortions. Exp Brain Res; 2005 May;162(4):513-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent adaptations of left and right arms to opposite visual distortions.
  • Previous research has shown that subjects can adapt with either arm to an opposite visual distortion, and the two adaptive states can then be used in sequence to control the respective arm.
  • To extend this finding, we exposed the left and right arms of our subjects to opposite-directed rotations of the visual field alternately for 20 s each, and determined the time-course of adaptation, as well as aftereffects without visual feedback under uni- and bimanual conditions.
  • Our data confirm that two adaptive states can co-exist in the sensorimotor system, one for each arm.
  • We further found that the time-course of adaptive improvement was similar for both arms, that the improvement was present as early as the first movement after a change of arm and discordance, and that the magnitude of adaptation was similar to control data yielded by a single arm and discordance.
  • Taken together, these findings suggest that the two adaptive states were formed concurrently, and without mutual interference.
  • They were smaller but still appreciable under bimanual conditions; the two arms moved at the same time in different directions even though they were aimed at a common visual target.
  • This outcome indicates that the two adaptive states were not merely of a strategic nature, but rather changed the rules by which sensory information was transformed into motor outputs; it also suggests that the two states not only co-exist, but can also be engaged concurrently in movement control.

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  • (PMID = 15754178.001).
  • [ISSN] 0014-4819
  • [Journal-full-title] Experimental brain research
  • [ISO-abbreviation] Exp Brain Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
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90. Wang J, Sainburg RL: The dominant and nondominant arms are specialized for stabilizing different features of task performance. Exp Brain Res; 2007 Apr;178(4):565-70
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The dominant and nondominant arms are specialized for stabilizing different features of task performance.
  • We have previously proposed a model of motor lateralization, in which the two arms are differentially specialized for complementary control processes.
  • We now directly test this model of lateralization by comparing performance of the two arms under two different tasks: one in which reaching movement is made from one fixed starting position to three different target positions; and the other in which reaching is made from three different starting positions to one fixed target position.
  • These findings contradict the idea that motor lateralization reflects a global advantage of one "dominant" hemisphere/limb system.
  • Instead, each hemisphere/limb system appears specialized for stabilizing different aspects of task performance.

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  • (PMID = 17380323.001).
  • [ISSN] 0014-4819
  • [Journal-full-title] Experimental brain research
  • [ISO-abbreviation] Exp Brain Res
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / R01HD39311
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
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91. Ni X, Li X, Fang X, Li N, Cui W, Zhang B: NGF/TrkA-mediated Kidins220/ARMS signaling activated in the allergic airway challenge in mice. Ann Allergy Asthma Immunol; 2010 Oct;105(4):299-306
MedlinePlus Health Information. consumer health - Asthma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] NGF/TrkA-mediated Kidins220/ARMS signaling activated in the allergic airway challenge in mice.
  • OBJECTIVE: To investigate whether the downstream protein ankyrin-rich membrane spanning (ARMS), a novel transmembrane substrate of protein kinase D (Kidins220), is activated in the pathogenesis of asthma.
  • The effects of NGF and TrkA on Kidins220/ARMS in an allergic airway challenge were assessed by administering anti-NGF or anti-TrkA antibody to the mice.
  • Pathologic changes in the bronchi and lung tissues were examined by means of hematoxylin and eosin staining; the inflammatory cells in the bronchoalveolar lavage fluid (BALF) were counted; and co-expression of ARMS and TrkA in BALF cells was observed by means of immunofluorescence.
  • In addition, Kidins220/ARMS, CrkL, NGF, TrkA protein, and Kidins220 messenger RNA levels were determined using Western blot or quantitative reverse transcription-polymerase chain reaction.
  • Compared with expression in control animals, Kidins220/ARMS, CrkL, NGF, and TrkA were overexpressed in the lungs after allergen challenge.
  • Moreover, after the mice were treated with anti-NGF or anti-TrkA, the Kidins220/ARMS levels and allergen-induced airway inflammation decreased.
  • CONCLUSIONS: These results suggest that Kidins220/ARMS partly participates in the pathogenesis of asthma through the NGF-TrkA signaling pathway, possibly representing a new mechanism in asthma.
  • [MeSH-major] Ankyrins / metabolism. Asthma / immunology. Bronchi / metabolism. Membrane Proteins / metabolism. Nerve Growth Factor / metabolism. Receptor, trkA / metabolism
  • [MeSH-minor] Animals. Antibodies, Monoclonal / administration & dosage. Bronchoalveolar Lavage Fluid / cytology. Bronchoalveolar Lavage Fluid / immunology. Cells, Cultured. Disease Models, Animal. Gene Expression Regulation / drug effects. Humans. Mice. Mice, Inbred BALB C. Signal Transduction / drug effects. Signal Transduction / immunology

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  • [Copyright] Copyright © 2010 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20934630.001).
  • [ISSN] 1081-1206
  • [Journal-full-title] Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • [ISO-abbreviation] Ann. Allergy Asthma Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ankyrins; 0 / Antibodies, Monoclonal; 0 / Kidins220 protein, mouse; 0 / Membrane Proteins; 9061-61-4 / Nerve Growth Factor; EC 2.7.10.1 / Receptor, trkA
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92. Hirano M, Hirano T: Opening closed arms: long-distance activation of SMC ATPase by hinge-DNA interactions. Mol Cell; 2006 Jan 20;21(2):175-86

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Opening closed arms: long-distance activation of SMC ATPase by hinge-DNA interactions.
  • Structural maintenance of chromosomes (SMC) proteins form a V-shaped dimer in which a central hinge domain connects two coiled-coil arms, each having an ATP binding head domain at its distal end.
  • An initial interaction of the hinge domain with DNA leads to opening of the arms by triggering hydrolysis of ATP bound to the head domains, which are located approximately 50 nm away from the hinge.
  • [MeSH-minor] Adenosine Triphosphate / metabolism. Amino Acid Sequence. Archaeal Proteins / chemistry. Archaeal Proteins / genetics. Archaeal Proteins / metabolism. Bacterial Proteins / chemistry. Bacterial Proteins / genetics. Bacterial Proteins / metabolism. Binding Sites / genetics. Enzyme Activation. Humans. In Vitro Techniques. Kinetics. Models, Biological. Models, Molecular. Molecular Sequence Data. Point Mutation. Protein Structure, Tertiary. Recombinant Proteins / chemistry. Recombinant Proteins / genetics. Recombinant Proteins / metabolism. Sequence Homology, Amino Acid

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  • (PMID = 16427008.001).
  • [ISSN] 1097-2765
  • [Journal-full-title] Molecular cell
  • [ISO-abbreviation] Mol. Cell
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Archaeal Proteins; 0 / Bacterial Proteins; 0 / Chromosomal Proteins, Non-Histone; 0 / Recombinant Proteins; 8L70Q75FXE / Adenosine Triphosphate; 9007-49-2 / DNA; EC 3.6.1.- / Adenosine Triphosphatases
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93. Tor PC, Lee HY: Comparison of attitudes of psychiatrists vs primary healthcare physicians in Singapore towards at risk mental states (ARMS). Ann Acad Med Singapore; 2009 May;38(5):442-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of attitudes of psychiatrists vs primary healthcare physicians in Singapore towards at risk mental states (ARMS).
  • AIMS: It is possible to define at risk mental states (ARMS) that predict conversion to schizophrenia in up to 40% of help seeking individuals within a year of screening.
  • Treatment of ARMS is controversial due to difficulties with diagnosis and uncertainties of treatment effectiveness.
  • This survey was conducted to assess and compare attitudes of Singapore psychiatrists vs primary healthcare physicians towards ARMS.
  • MATERIALS AND METHODS: An anonymous survey containing a clinical vignette and questions related to the diagnosis and management of ARMS was sent out to all registered psychiatrists/ psychiatry trainees and all doctors in a public primary healthcare group in Singapore.
  • The proportion of psychiatrists diagnosing ARMS vs psychosis was 44.8% vs 43.7% respectively.
  • Among psychiatrists who diagnosed ARMS, 74.4% (29/39) would treat the patient with active management.
  • Of the total number of psychiatrists surveyed, 49.4% would advocate population screening of high risk groups compared to 30.8% of primary healthcare physicians.
  • And 64.4% of psychiatrists felt that there was no consensus regarding the management of ARMS.
  • CONCLUSIONS: There is currently clinical equipoise with regards to both diagnosis and management of ARMS in Singapore.
  • Primary care physicians may be more likely to diagnose psychosis vs ARMS when compared to psychiatrists.
  • Psychiatrists were more likely than primary healthcare physicians to advocate population screening of ARMS in high-risk groups.
  • Most psychiatrists would manage ARMS actively.
  • [MeSH-major] Attitude of Health Personnel. Mental Disorders / diagnosis. Physicians, Family. Psychiatry
  • [MeSH-minor] Adult. Female. Health Care Surveys. Humans. Male. Middle Aged. Risk Assessment. Schizophrenia. Singapore. Young Adult

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  • (PMID = 19521648.001).
  • [ISSN] 0304-4602
  • [Journal-full-title] Annals of the Academy of Medicine, Singapore
  • [ISO-abbreviation] Ann. Acad. Med. Singap.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Singapore
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94. Eboue C, Marcus-Braun N, von Theobald P: Cystocele repair by transobturator four arms mesh: monocentric experience of first 123 patients. Int Urogynecol J; 2010 Jan;21(1):85-93

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystocele repair by transobturator four arms mesh: monocentric experience of first 123 patients.
  • CONCLUSIONS: Treatment of cystocele using transobturator four arms mesh appears to reduce the risk of recurrence at 1 year, along with high rate of patient's satisfaction.
  • The transobturator path of the prosthesis arms seems devoid of serious per- and post-operative risks and allows restoring continence when SUI is present.

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  • (PMID = 19787281.001).
  • [ISSN] 1433-3023
  • [Journal-full-title] International urogynecology journal
  • [ISO-abbreviation] Int Urogynecol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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95. Li H, Harris DA, Xu B, Wrzesinski PJ, Lozovoy VV, Dantus M: Standoff and arms-length detection of chemicals with single-beam coherent anti-Stokes Raman scattering. Appl Opt; 2009 Feb 1;48(4):B17-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Standoff and arms-length detection of chemicals with single-beam coherent anti-Stokes Raman scattering.
  • Characteristic Raman lines for several chemicals are successfully obtained from arms-length and 12 m standoff distances.

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  • (PMID = 19183575.001).
  • [ISSN] 1539-4522
  • [Journal-full-title] Applied optics
  • [ISO-abbreviation] Appl Opt
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Explosive Agents; 0 / Hazardous Substances
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96. Najafi M, Firoozrai M, Gohari HL, Zavarehie A, Basiri G: Direct haplotyping of bi-allelic SNPs using ARMS and RFLP analysis techniques. Biomol Eng; 2007 Dec;24(6):609-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Direct haplotyping of bi-allelic SNPs using ARMS and RFLP analysis techniques.
  • In this study, we have designed a reliable method for direct haplotyping of polymorphic sites using the amplification refractory mutation system (ARMS) and restriction fragment length polymorphism (RFLP) analysis techniques.

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  • (PMID = 17913580.001).
  • [ISSN] 1389-0344
  • [Journal-full-title] Biomolecular engineering
  • [ISO-abbreviation] Biomol. Eng.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] EC 3.1.8.1 / Aryldialkylphosphatase; EC 3.1.8.1 / PON1 protein, human
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97. Michilsens F, Vereecke EE, D'Août K, Aerts P: Muscle moment arms and function of the siamang forelimb during brachiation. J Anat; 2010 Nov;217(5):521-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Muscle moment arms and function of the siamang forelimb during brachiation.
  • Moment arms have an important modulating impact on muscle function, as they represent the capacity of the muscle to convert muscle action into limb movements.
  • When brachiating on a more complex setup, the siamang will flex the elbows to angles that induce maximum moment arms as well.

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  • [Copyright] © 2010 The Authors. Journal of Anatomy © 2010 Anatomical Society of Great Britain and Ireland.
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  • (PMID = 20673298.001).
  • [ISSN] 1469-7580
  • [Journal-full-title] Journal of anatomy
  • [ISO-abbreviation] J. Anat.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3035860
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98. Barkus E, Stirling J, French P, Morrison A, Bentall R, Lewis S: Distress and metacognition in psychosis prone individuals: comparing high schizotypy to the at-risk mental state. J Nerv Ment Dis; 2010 Feb;198(2):99-104
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distress and metacognition in psychosis prone individuals: comparing high schizotypy to the at-risk mental state.
  • Both schizotypy and at-risk mental states (ARMS: prodromal states) define individuals at risk for psychotic symptoms.
  • ARMS individuals are, by definition, help-seeking and therefore at greater risk.
  • We tested whether high schizotypes and ARMS exist along the same continuum by examining maladaptive metacognitions and distress.
  • About 95 healthy volunteers (39% male; mean age, 22.8 years) completed the Schizotypal Personality Questionnaire, the Launay-Slade Hallucinations Scale, Metacognitions Questionnaire (MCQ), and the General Health Questionnaire, and 58 help seeking individuals with ARMS status (41% male; mean age, 22.2 years) completed the Metacognitions Questionnaire and General Health Questionnaire.
  • With increasing expression of schizotypy and hallucinatory proneness healthy volunteers became difficult to differentiate from ARMS patients and showed similarities in distress and metacognitive abnormalities.
  • Results suggest healthy volunteers who express both schizotypal trait and proneness to hallucinations have cognitive processes in common with ARMS patients.
  • [MeSH-major] Cognition Disorders / epidemiology. Depressive Disorder / epidemiology. Hallucinations / epidemiology. Psychotic Disorders / epidemiology. Schizotypal Personality Disorder / epidemiology. Self Concept
  • [MeSH-minor] Female. Health Status. Humans. Male. Neuropsychological Tests. Patient Acceptance of Health Care / statistics & numerical data. Prevalence. Risk Factors. Severity of Illness Index. Surveys and Questionnaires. Young Adult

  • MedlinePlus Health Information. consumer health - Psychotic Disorders.
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  • (PMID = 20145483.001).
  • [ISSN] 1539-736X
  • [Journal-full-title] The Journal of nervous and mental disease
  • [ISO-abbreviation] J. Nerv. Ment. Dis.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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99. Grzendowski M, Wolter M, Riemenschneider MJ, Knobbe CB, Schlegel U, Meyer HE, Reifenberger G, Stühler K: Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19q. Neuro Oncol; 2010 Mar;12(3):243-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19q.
  • Combined deletion of chromosomal arms 1p and 19q is an independent prognostic marker in patients with oligodendroglial brain tumors, including oligodendrogliomas and oligoastrocytomas.
  • However, the relevant genes in these chromosome arms and the molecular mechanisms underlying the prognostic significance of 1p/19q deletion are yet unknown.

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  • (PMID = 20167812.001).
  • [ISSN] 1523-5866
  • [Journal-full-title] Neuro-oncology
  • [ISO-abbreviation] Neuro-oncology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2940597
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100. Nikas I, Theofanopoulou M, Lampropoulou P, Pourtsidis A, Hadjigeorgi C, Kosmidis H: Optic pathway glioma associated with orbital rhabdomyosarcoma and bilateral optic nerve sheath dural ectasia in a child with neurofibromatosis-1. Pediatr Radiol; 2006 Nov;36(11):1200-3
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  • [Title] Optic pathway glioma associated with orbital rhabdomyosarcoma and bilateral optic nerve sheath dural ectasia in a child with neurofibromatosis-1.
  • Neurofibromatosis-1 (NF-1) is a multisystem disorder presenting with a variety of clinical and imaging manifestations.
  • We present a 2(1/2)-year-old boy with NF-1 who demonstrated coexisting optic pathway glioma with involvement of the chiasm and optic nerve, orbital alveolar rhabdomyosarcoma and bilateral optic nerve sheath dural ectasia.
  • [MeSH-major] Dilatation, Pathologic / diagnostic imaging. Glioma / diagnostic imaging. Neurofibromatoses / diagnostic imaging. Optic Nerve Neoplasms / diagnostic imaging. Orbital Neoplasms / diagnostic imaging. Rhabdomyosarcoma / diagnostic imaging






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