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1. Ansari SH, Irfan M, Farzana, Panjwani VK, Shamsi TS: In-vivo purging with the anti-CD20 antibody rituximab along with standard allogeneic peripheral blood stem cell transplantation (PBSCT) for relapsed childhood pre-B acute lymphoblastic leukaemia (ALL). J Coll Physicians Surg Pak; 2006 Jan;16(1):67-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] In-vivo purging with the anti-CD20 antibody rituximab along with standard allogeneic peripheral blood stem cell transplantation (PBSCT) for relapsed childhood pre-B acute lymphoblastic leukaemia (ALL).
  • He did not develop acute graft versus host disease (aGvHD) but localized chronic GvHD developed.

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  • (PMID = 16441995.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Immunologic Factors; 4F4X42SYQ6 / Rituximab
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2. Antao B, Bishop J, Shawis R, Thomson M: Clinical application and diagnostic yield of wireless capsule endoscopy in children. J Laparoendosc Adv Surg Tech A; 2007 Jun;17(3):364-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The indications for WCE was suspected Crohn's disease (CD) (18), obscure or occult gastrointestinal bleeding (7), polyposis syndromes (5), protein losing enteropathy (4), recurrent abdominal pain (2), and malabsorption syndrome (1).

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  • (PMID = 17570790.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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3. Russu R, Munteanu M, Cucer F, Gavrilovici C, Brumariu O: [Remission of primary vesicoureteral reflux in children with medical management]. Rev Med Chir Soc Med Nat Iasi; 2005 Oct-Dec;109(4):727-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We reviewed the records of 110 children (14 days - 16 years) admitted in the 4th Pediatric Clinic Iaşi with primary VUR, between 1994 - 2003, which had exclusive medical management and minimum one follow-up cystogram.
  • We used Kaplan-Meier curves to analyze the resolution rate of VUR during the follow-up in relation with initial grade, age at diagnosis, gender, recurrent urinary tract infections (UTIs) and the presence of renal scarring.

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  • (PMID = 16610167.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] rum
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Romania
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4. Reda SM, Afifi HM, Amine MM: Primary immunodeficiency diseases in Egyptian children: a single-center study. J Clin Immunol; 2009 May;29(3):343-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Sixty-four primary immunodeficiency patients were registered at the Pediatric Allergy and Immunology Department, Children's Hospital, Ain Shams University, Cairo, Egypt.
  • Recurrent severe infections were seen in all categories.

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  • (PMID = 19002574.001).
  • [ISSN] 1573-2592
  • [Journal-full-title] Journal of clinical immunology
  • [ISO-abbreviation] J. Clin. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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5. Shah SR, Jegapragasan M, Fox MD, Prince JM, Segura BJ, Kane TD: A review of laparoscopic Nissen fundoplication in children weighing less than 5 kg. J Pediatr Surg; 2010 Jun;45(6):1165-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: All cases of LNF attempted in children weighing less than 5 kg since January 2003 at a tertiary-care pediatric hospital were reviewed after Institutional Review Board approval.
  • Six patients (5%) had a complication or recurrent gastroesophageal reflux.
  • Three patients had recurrent reflux, one of which underwent another LNF.
  • Another required a redo LNF after a disrupted wrap was noted at a recurrent hiatal hernia repair.

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  • [Copyright] Published by Elsevier Inc.
  • (PMID = 20620313.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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6. Bahi-Buisson N, Poirier K, Boddaert N, Saillour Y, Castelnau L, Philip N, Buyse G, Villard L, Joriot S, Marret S, Bourgeois M, Van Esch H, Lagae L, Amiel J, Hertz-Pannier L, Roubertie A, Rivier F, Pinard JM, Beldjord C, Chelly J: Refinement of cortical dysgeneses spectrum associated with TUBA1A mutations. J Med Genet; 2008 Oct;45(10):647-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In four patients, the mutations identified, c.1190T>C (p.L397P), c.1265G>A (p.R422H), c.1264C>T (p.R422C), c.1306G>T (p.G436R), have not been reported before and in two others, the mutation corresponds to a recurrent missense mutation, c.790C>T (p.R264C), likely to be a hot spot of mutation.


7. Boerma EG, Siebert R, Kluin PM, Baudis M: Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas: a historical review of cytogenetics in the light of todays knowledge. Leukemia; 2009 Feb;23(2):225-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the remaining cases, additional recurrent but partially exclusive abnormalities included gains at chromosomes 1q, 7 and 12, and losses of 6q, 13q32-34 and 17p.
  • Within the core subset, no differences were found between pediatric and adult patients.

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  • (PMID = 18923440.001).
  • [ISSN] 1476-5551
  • [Journal-full-title] Leukemia
  • [ISO-abbreviation] Leukemia
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 59
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8. Meijerink JP, den Boer ML, Pieters R: New genetic abnormalities and treatment response in acute lymphoblastic leukemia. Semin Hematol; 2009 Jan;46(1):16-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] New genetic abnormalities and treatment response in acute lymphoblastic leukemia.
  • Numerous genetic abnormalities have been identified in acute lymphoblastic leukemia (ALL).
  • Here we review the recurrent abnormalities with emphasis on those recently discovered, and discuss their association with chemotherapy resistance or sensitivity and with clinical response to therapy.
  • [MeSH-major] Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics. Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics

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  • (PMID = 19100364.001).
  • [ISSN] 0037-1963
  • [Journal-full-title] Seminars in hematology
  • [ISO-abbreviation] Semin. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Transcription Factors
  • [Number-of-references] 70
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9. Jonsson AM, Papadogiannakis N, Granath A, Haggstrom J, Schaffer M, Uzunel M, Westgren M: Maternal microchimerism in juvenile tonsils and adenoids. Pediatr Res; 2010 Sep;68(3):199-204
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All the children underwent surgery because of recurrent tonsillitis or respiratory obstruction.

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  • (PMID = 20531252.001).
  • [ISSN] 1530-0447
  • [Journal-full-title] Pediatric research
  • [ISO-abbreviation] Pediatr. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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10. Adeli MM, Buckley RH: Why newborn screening for severe combined immunodeficiency is essential: a case report. Pediatrics; 2010 Aug;126(2):e465-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report the case of a 4-month-old white girl with a 2-month history of an oral ulcer, intermittent fever, recurrent otitis, decreased appetite, weight loss, and a new respiratory illness with hypoxemia.


11. Chang HH, Lu MY, Jou ST, Lin KH, Tien HF, Lin DT: Cytogenetics in childhood acute lymphoblastic leukemia in Taiwan: a single-institutional experience. Pediatr Hematol Oncol; 2006 Sep;23(6):495-506
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytogenetics in childhood acute lymphoblastic leukemia in Taiwan: a single-institutional experience.
  • Of the patients with abnormal karyotypes, recurrent structural abnormalities were determined in 31 (50%) cases, with the most frequent t(9;22).
  • [MeSH-major] Chromosome Aberrations / statistics & numerical data. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics


12. Li QW, Song HR, Mahajan RH, Suh SW, Lee SH: Deformity correction with external fixator in pseudoachondroplasia. Clin Orthop Relat Res; 2007 Jan;454:174-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Distraction osteogenesis was used in 20 segments and acute deformity correction was done in six segments.
  • Recurrent deformity in children and refracture in adults were related to poor results.

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  • (PMID = 16957646.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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13. Ure BM, Schier F, Schmidt AI, Nustede R, Petersen C, Jesch NK: Laparoscopic resection of congenital choledochal cyst, choledochojejunostomy, and extraabdominal Roux-en-Y anastomosis. Surg Endosc; 2005 Aug;19(8):1055-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All except one patient had intermittent jaundice or recurrent pancreatitis.
  • In one patient, recurrent cholangitis and a dilated Roux-en-Y loop led to correction of some kinking of the loop via laparotomy after 3 months.

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  • (PMID = 15942810.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Germany
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14. Pickett W, Brison RJ, Berg RL, Zentner J, Linneman J, Marlenga B: Pediatric farm injuries involving non-working children injured by a farm work hazard: five priorities for primary prevention. Inj Prev; 2005 Feb;11(1):6-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric farm injuries involving non-working children injured by a farm work hazard: five priorities for primary prevention.
  • OBJECTIVES: To describe pediatric farm injuries experienced by children who were not engaged in farm work, but were injured by a farm work hazard and to identify priorities for primary prevention.
  • SUBJECTS: Three hundred and seventy known non-work childhood injuries from a larger case series of 934 injury events covering the full spectrum of pediatric farm injuries.
  • METHODS: Recurrent injury patterns were described by child demographics, external cause of injury, and associated child activities.
  • Factors contributing to pediatric farm injury were described.
  • CONCLUSIONS: Substantial proportions of pediatric farm injuries are experienced by children who are not engaged in farm work.
  • Study findings could lead to more refined and focused pediatric farm injury prevention initiatives.

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  • (PMID = 15691981.001).
  • [ISSN] 1353-8047
  • [Journal-full-title] Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention
  • [ISO-abbreviation] Inj. Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1730186
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15. Grasso DL, Segat L, Zocconi E, Radillo O, Trevisiol C, Crovella S: MBL expression in patients with recurrent tonsillitis. Int J Pediatr Otorhinolaryngol; 2009 Nov;73(11):1550-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MBL expression in patients with recurrent tonsillitis.
  • OBJECTIVE: We evaluated mannose binding lectin (MBL) protein production and histological localization, MBL2 gene expression and genotypes distribution in patients characterized by recurrent tonsillitis, with the aim of verifying the innate immune response to the infection and inflammation occurring in the tonsils.
  • MBL Oligomer ELISA kit was used to quantify the level of MBL in the serum of the 30 patients with recurrent tonsillitis.
  • Our findings suggest an important role of MBL protein in the innate immune response of the tonsil to pathogens, as in recurrent infection and inflammation.

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  • (PMID = 19716183.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Mannose-Binding Lectin
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16. Arush MW, Israel O, Postovsky S, Militianu D, Meller I, Zaidman I, Sapir AE, Bar-Shalom R: Positron emission tomography/computed tomography with 18fluoro-deoxyglucose in the detection of local recurrence and distant metastases of pediatric sarcoma. Pediatr Blood Cancer; 2007 Dec;49(7):901-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Positron emission tomography/computed tomography with 18fluoro-deoxyglucose in the detection of local recurrence and distant metastases of pediatric sarcoma.
  • BACKGROUND: Combined positron emission tomography with (18)fluoro-deoxyglucose and computed tomography (FDG-PET/CT) has been used in the diagnosis and staging of various malignancies, but their use in the management of pediatric sarcomas is less well defined.
  • The potential role of FDG-PET/CT in the diagnosis of local recurrence and distant metastases of pediatric sarcomas was investigated.
  • CONCLUSION: FDG-PET/CT may be useful and complementary to other imaging modalities for the detection of recurrent pediatric sarcomas, especially at the primary site.

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  • (PMID = 17252575.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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17. al Kandari H, Katsumata N, Alexander S, Rasoul MA: Homozygous mutation of P450 side-chain cleavage enzyme gene (CYP11A1) in 46, XY patient with adrenal insufficiency, complete sex reversal, and agenesis of corpus callosum. J Clin Endocrinol Metab; 2006 Aug;91(8):2821-6
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  • The clinical findings of nearly undetectable levels of steroid hormones at presentation are explained by the total disruption of steroidogenic cells later on, with recurrent ACTH stimulation leading to intramitochondrial cholesterol accumulation and cell death (a two-hit mechanism).

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  • (PMID = 16705068.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 73R90F7MQ8 / Pregnenolone; 97C5T2UQ7J / Cholesterol; EC 1.14.15.6 / Cholesterol Side-Chain Cleavage Enzyme; EC 3.1.21.4 / Deoxyribonucleases, Type II Site-Specific; EC 3.1.21.4 / GCGC-specific type II deoxyribonucleases
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18. Janeway KA, Walkley CR: Modeling human osteosarcoma in the mouse: From bedside to bench. Bone; 2010 Nov;47(5):859-65
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  • At presentation approximately 20% of patients have metastases and almost all patients with recurrent OS have metastatic disease and cure rates for patients with metastatic or recurrent disease remain poor (<20% survival).

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20696288.001).
  • [ISSN] 1873-2763
  • [Journal-full-title] Bone
  • [ISO-abbreviation] Bone
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
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19. Matthyssens LE, Philippe P: A new minimally invasive technique for the repair of femoral hernia in children: about 13 laparoscopic repairs in 10 patients. J Pediatr Surg; 2009 May;44(5):967-71
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  • Since the advent of laparoscopic treatment of inguinal hernia in children, laparoscopy has been proposed to offer an accurate diagnosis and treatment, especially in case of recurrent hernia or bilateral disease.
  • This review was undertaken to report our experience with the primary laparoscopic diagnosis and treatment of pediatric femoral hernias and to investigate its safety and feasibility.
  • METHODS: All cases of pediatric femoral hernia in a consecutive series of children treated laparoscopically for groin hernias in a single institution over a 7-year period (2001-2007) were identified and studied for patient characteristics, presentation, pre- and perioperative findings, details of the operative repair, and postoperative outcome.
  • RESULTS: Out of a prospectively studied series of 462 laparoscopic pediatric inguinal hernia repairs in 389 patients, 13 femoral hernias were treated in 10 patients (6 boys), with a mean age of 71/2 years (range, 1.7-12).
  • CONCLUSIONS: Laparoscopy provides a straightforward, accurate diagnosis for the rare and often missed pediatric femoral hernias.

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  • (PMID = 19433180.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Trautmann E, Kröner-Herwig B: A randomized controlled trial of Internet-based self-help training for recurrent headache in childhood and adolescence. Behav Res Ther; 2010 Jan;48(1):28-37
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  • [Title] A randomized controlled trial of Internet-based self-help training for recurrent headache in childhood and adolescence.
  • Sixty-five children and adolescents (mean age: 12.7 years) with recurrent headache (at least 2 attacks per month) were each assigned to one of the three treatment conditions.
  • The results support the use of Internet programs for pediatric recurrent headache, especially given their accessibility and suitability for children and adolescents.

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  • [Copyright] Copyright 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 19782343.001).
  • [ISSN] 1873-622X
  • [Journal-full-title] Behaviour research and therapy
  • [ISO-abbreviation] Behav Res Ther
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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21. Cobellis G, Cruccetti A, Mastroianni L, Amici G, Martino A: One-trocar transumbilical laparoscopic-assisted management of Meckel's diverticulum in children. J Laparoendosc Adv Surg Tech A; 2007 Apr;17(2):238-41
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  • Three patients had recurrent abdominal pain and abdominal ultrasound scan showed a cystlike structure.

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  • (PMID = 17484657.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Spivacow FR, Negri AL, del Valle EE, Calviño I, Fradinger E, Zanchetta JR: Metabolic risk factors in children with kidney stone disease. Pediatr Nephrol; 2008 Jul;23(7):1129-33
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  • The evaluation of metabolic risk factor in children with renal stone disease is the basis of medical treatment aimed at preventing recurrent stone events and the growth of preexisting calculi.
  • The mean age of our pediatric patients was 10.7 years, and the male:female ratio was 1.14:1.0.

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  • [CommentIn] Pediatr Nephrol. 2009 Oct;24(10):2077-8 [19350277.001]
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  • (PMID = 18324422.001).
  • [ISSN] 0931-041X
  • [Journal-full-title] Pediatric nephrology (Berlin, Germany)
  • [ISO-abbreviation] Pediatr. Nephrol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Citrates; 268B43MJ25 / Uric Acid; I38ZP9992A / Magnesium
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23. Boston M, Rutter M, Myer CM 3rd, Cotton RT: Airway reconstruction in children with recurrent respiratory papillomatosis. Int J Pediatr Otorhinolaryngol; 2006 Jun;70(6):1097-101
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  • [Title] Airway reconstruction in children with recurrent respiratory papillomatosis.
  • OBJECTIVE: To determine if children with recurrent respiratory papillomatosis were at increased risk of complications due to their disease following major airway reconstruction.
  • METHODS: We retrospectively reviewed our airway surgery database and the medical records of all children diagnosed with recurrent respiratory papillomatosis who were evaluated at Cincinnati Children's Hospital Medical Center between January 1998 and August 2003.
  • All patients with active airway papillomas or a history of recurrent respiratory papillomatosis who underwent open airway reconstruction at our institution were included in the study.
  • RESULTS: Seven children with recurrent respiratory papillomatosis underwent major airway reconstruction.
  • CONCLUSIONS: Major airway reconstruction can be safely performed in children with recurrent respiratory papillomatosis.


24. Kizer WS, Armenakas NA, Brandes SB, Cavalcanti AG, Santucci RA, Morey AF: Simplified reconstruction of posterior urethral disruption defects: limited role of supracrural rerouting. J Urol; 2007 Apr;177(4):1378-81; discussion 1381-2
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  • Supracrural urethral rerouting was performed in only 4 patients (3%), of whom 3 (75%) experienced recurrent stenosis.
  • Abdominoperineal reconstruction, which was reserved mainly for salvage and pediatric cases, was required to reconstruct complex defects in 5 of the 142 cases (4%) and it was successful in 4 (80%).

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  • (PMID = 17382736.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Ibrahim AH, Al Malki TA, Hamza AF, Bahnassy AF: Congenital esophageal stenosis associated with esophageal atresia: new concepts. Pediatr Surg Int; 2007 Jun;23(6):533-7
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  • Excluding the case of pure EA with gastric pull up, all patients suffered from feeding problems and recurrent aspiration.

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  • (PMID = 17437115.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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26. Najada AS, Dahabreh MM: Clinical profile of cystic fibrosis. Atypical presentation. Saudi Med J; 2010 Feb;31(2):185-8
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  • METHODS: A retrospective review was carried out on all children (n=90) with the diagnosis of classical cystic fibrosis who attended the Respiratory Pediatric Clinic at King Hussein Medical Center, Amman, Jordan from January 2002--December 2008.
  • The most common initial classical presenting manifestation was recurrent wheezy chest (24%).


27. Gupta DK, Ahmed S, Garg K, Mahapatra AK: Regrowth of septal spur in split cord malformation. Pediatr Neurosurg; 2010;46(3):242-4
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  • We report a 3-year-old female patient who developed recurrent fibro-osseous spur after primary excision.

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  • [Copyright] Copyright © 2010 S. Karger AG, Basel.
  • (PMID = 21051925.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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28. Albanese CT, Rengal S, Bermudez D: A novel laparoscopic technique for the repair of pediatric umbilical and epigastric hernias. J Pediatr Surg; 2006 Apr;41(4):859-62
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  • [Title] A novel laparoscopic technique for the repair of pediatric umbilical and epigastric hernias.
  • BACKGROUND/PURPOSE: The aim of this study was to determine whether a novel laparoscopic technique for pediatric umibilical and epigastric hernia repair is safe, quick, effective, durable, and cosmetically acceptable.
  • There have been no recurrent hernias, and patient/parent satisfaction was subjectively excellent.

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  • (PMID = 16567211.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Leavey PJ, Mascarenhas L, Marina N, Chen Z, Krailo M, Miser J, Brown K, Tarbell N, Bernstein ML, Granowetter L, Gebhardt M, Grier HE, Children's Oncology Group: Prognostic factors for patients with Ewing sarcoma (EWS) at first recurrence following multi-modality therapy: A report from the Children's Oncology Group. Pediatr Blood Cancer; 2008 Sep;51(3):334-8
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  • BACKGROUND: The prognosis for patients with recurrent Ewing sarcoma (EWS) is very poor with 5-year survival of 13%.
  • Twenty-one percent of patients, with recurrent or progressive disease >or=2 years from initial diagnosis, had an estimated 5-year survival of 30% (vs. 7% estimated 5-year survival with an earlier recurrence).

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
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  • (PMID = 18506764.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U10 CA098543-06; United States / NCI NIH HHS / CA / CA 30969; United States / NCI NIH HHS / CA / CA 98543; None / None / / U10 CA098413-05; United States / NCI NIH HHS / CA / U10 CA098413-05; United States / NCI NIH HHS / CA / CA 13539; United States / NCI NIH HHS / CA / U10 CA098543; None / None / / U10 CA098543-06
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS123701; NLM/ PMC2728357
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30. Messinger Y, Gaynon P, Raetz E, Hutchinson R, Dubois S, Glade-Bender J, Sposto R, van der Giessen J, Eckroth E, Bostrom BC: Phase I study of bortezomib combined with chemotherapy in children with relapsed childhood acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia (TACL) consortium. Pediatr Blood Cancer; 2010 Aug;55(2):254-9
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  • [Title] Phase I study of bortezomib combined with chemotherapy in children with relapsed childhood acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia (TACL) consortium.
  • BACKGROUND: Outcomes remain poor for children after relapse of acute lymphoblastic leukemia (ALL), especially after early marrow relapse.
  • Bortezomib is a proteasome inhibitor with in vitro synergy with corticosteroids and clinical activity in human lymphoid malignancies.
  • PROCEDURE: This is a Phase I study of escalating doses bortezomib administered days 1, 4, 8, and 11, added to 4-drug induction chemotherapy with vincristine, dexamethasone, pegylated L-asparaginase, and doxorubicin (VXLD) in children with relapsed ALL.
  • Six of nine evaluable patients (67%) achieved a complete response (CR), and one had a bone marrow CR with persistent central nervous system leukemia.
  • CONCLUSIONS: The combination of bortezomib (1.3 mg/m(2)) with VXLD is active with acceptable toxicity in pretreated pediatric patients with relapsed ALL.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Boronic Acids / administration & dosage. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Pyrazines / administration & dosage


31. Kabra SK, Lodha R, Ramesh P, Sarthi M: Fiberoptic bronchoscopy in children an audit from a tertiary care center. Indian Pediatr; 2008 Nov;45(11):917-9
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  • The common indications were persistent/ recurrent pneumonia, persistent collapse, stridor and pulmonary hemorrhage.

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  • (PMID = 19029566.001).
  • [ISSN] 0019-6061
  • [Journal-full-title] Indian pediatrics
  • [ISO-abbreviation] Indian Pediatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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32. Blaiss MS: Pediatric allergic rhinitis: physical and mental complications. Allergy Asthma Proc; 2008 Jan-Feb;29(1):1-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric allergic rhinitis: physical and mental complications.
  • Most AR develops during the pediatric years and it is the most common chronic allergic disorder seen in children.
  • Under physical complications, otitis media with effusion, recurrent and/or chronic sinusitis, asthma, and snoring impact children with AR.

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  • (PMID = 18302831.001).
  • [ISSN] 1088-5412
  • [Journal-full-title] Allergy and asthma proceedings
  • [ISO-abbreviation] Allergy Asthma Proc
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 40
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33. Rakoczy G, Brown B, Barman D, Howell T, Shabani A, Khalil B, Sheehan Z: KTP laser: an important tool in refractory recurrent tracheo-esophageal fistula in children. Int J Pediatr Otorhinolaryngol; 2010 Mar;74(3):326-7
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  • [Title] KTP laser: an important tool in refractory recurrent tracheo-esophageal fistula in children.
  • We recommend the use of this laser in cases of recurrent tracheo-esophageal fistula especially when other means have failed.

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  • [Copyright] Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20060599.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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34. Rainov NG, Söling A: Clinical studies with targeted toxins in malignant glioma. Rev Recent Clin Trials; 2006 May;1(2):119-31
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  • Four targeted toxins advanced to at least phase II clinical trials and are being used for treatment of adult or pediatric patients with recurrent or progressive malignant glioma.

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  • (PMID = 18473963.001).
  • [ISSN] 1574-8871
  • [Journal-full-title] Reviews on recent clinical trials
  • [ISO-abbreviation] Rev Recent Clin Trials
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United Arab Emirates
  • [Chemical-registry-number] 0 / Bacterial Toxins; 0 / Exotoxins; 0 / IL13-PE38; 0 / Immunologic Factors; 0 / Immunotoxins; 0 / Interleukin-13; 0 / Recombinant Fusion Proteins; 0 / Tf-CRM107; 0 / Transferrin; 0 / Transforming Growth Factor alpha; 0 / interleukin-4-Pseudomonas exotoxin; 0 / transforming growth factor(alpha)-Pseudomonas aeruginosa exotoxin (38); 207137-56-2 / Interleukin-4
  • [Number-of-references] 85
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35. Mukherjee P, Chacko B, Singh T, Pawar G, Kaur H: Prevalence of Helicobacter pylori infection in children with recurrent abdominal pain. Trop Gastroenterol; 2005 Apr-Jun;26(2):102-4
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  • [Title] Prevalence of Helicobacter pylori infection in children with recurrent abdominal pain.
  • The present study was performed to study the prevalence of Helicobacter pylori (H. pylori) infection in children with recurrent abdominal pain (RAP).
  • Upper gastrointestinal endoscopy was performed with a fibreoptic pediatric sized endoscope in RAP cases after obtaining informed parental consent.

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  • (PMID = 16225059.001).
  • [ISSN] 0250-636X
  • [Journal-full-title] Tropical gastroenterology : official journal of the Digestive Diseases Foundation
  • [ISO-abbreviation] Trop Gastroenterol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] India
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36. Kiyak A, Yilmaz A, Turhan P, Sander S, Aydin G, Aydogan G: Unilateral multicystic dysplastic kidney: single-center experience. Pediatr Nephrol; 2009 Jan;24(1):99-104
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  • Ninety pediatric patients with unilateral MCDK followed by the Pediatric Nephrology Department of Bakirkoy Maternity and Children's Hospital between 1990 and 2007 were included in this retrospective study.
  • Indication of nephrectomy was arterial hypertension in 16 patients (23.1%), recurrent urinary tract infection (UTI) in 11 (15.9%), and severe abdominal pain in two (2.8%).

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  • (PMID = 18696120.001).
  • [ISSN] 0931-041X
  • [Journal-full-title] Pediatric nephrology (Berlin, Germany)
  • [ISO-abbreviation] Pediatr. Nephrol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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37. Choi J, Foss F: Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia. Yale J Biol Med; 2006 Dec;79(3-4):169-72
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  • [Title] Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia.
  • Refractory T-lymphoblastic leukemia in adults has a poor prognosis in patients who relapse after allogeneic stem cell transplantation, and relatively few new agents have demonstrated activity.
  • Clofarabine is a novel nucleoside analog that has been associated with significant clinical activity in relapsed pediatric B-ALL.
  • We used low dose clofarabine and induced a remission in a patient who relapsed in the skin and marrow after allogeneic transplant and was refractory to nelarabine and report a near complete response, suggesting significant activity for low intermittent dose clofarabine in patients with relapsed T-cell leukemias.
  • [MeSH-major] Adenine Nucleotides / therapeutic use. Arabinonucleosides / therapeutic use. Leukemia-Lymphoma, Adult T-Cell / drug therapy

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  • (PMID = 17940627.001).
  • [ISSN] 1551-4056
  • [Journal-full-title] The Yale journal of biology and medicine
  • [ISO-abbreviation] Yale J Biol Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adenine Nucleotides; 0 / Arabinonucleosides; 60158CV180 / nelarabine; 762RDY0Y2H / clofarabine
  • [Other-IDs] NLM/ PMC1994805
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38. Arena S, Romeo C, Borruto FA, Racchiusa S, Di Benedetto V, Arena F: Anterior urethral valves in children: an uncommon multipathogenic cause of obstructive uropathy. Pediatr Surg Int; 2009 Jul;25(7):613-6
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  • RESULTS: All pts had difficulty in voiding and eight had recurrent urinary tract infection.

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  • (PMID = 19517125.001).
  • [ISSN] 1437-9813
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] AYI8EX34EU / Creatinine
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39. Gulesserian T, Hron G, Endler G, Eichinger S, Wagner O, Kyrle PA: Marburg I polymorphism of factor VII-activating protease and risk of recurrent venous thromboembolism. Thromb Haemost; 2006 Jan;95(1):65-7
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  • [Title] Marburg I polymorphism of factor VII-activating protease and risk of recurrent venous thromboembolism.
  • Study endpoint was symptomatic recurrent VTE.
  • We conclude that FSAP Marburg I is, if at all, only a mild factor for recurrent VTE.

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  • [CommentIn] Thromb Haemost. 2006 May;95(5):907-8; author reply 908 [16676090.001]
  • (PMID = 16543963.001).
  • [ISSN] 0340-6245
  • [Journal-full-title] Thrombosis and haemostasis
  • [ISO-abbreviation] Thromb. Haemost.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anticoagulants; EC 3.4.21.- / HABP2 protein, human; EC 3.4.21.- / Serine Endopeptidases
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40. Aharoni S, Traves TA, Melamed E, Cohen S, Silver EL: MELAS syndrome associated with both A3243G-tRNALeu mutation and multiple mitochondrial DNA deletions. J Neurol Sci; 2010 Sep 15;296(1-2):101-3
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  • The syndrome of mitochondrial encephalopathy, lactic acidosis, and stroke-like episode (MELAS) is characterized clinically by recurrent focal neurological deficits, epilepsy, and short stature.

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  • [Copyright] 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20655066.001).
  • [ISSN] 1878-5883
  • [Journal-full-title] Journal of the neurological sciences
  • [ISO-abbreviation] J. Neurol. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA, Mitochondrial; 0 / RNA, Transfer, Leu; 9007-49-2 / DNA; EC 2.7.7.- / POLG protein, human; EC 2.7.7.7 / DNA-Directed DNA Polymerase
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41. El-Hallak M, Binstadt BA, Leichtner AM, Bennett CM, Neufeld EJ, Fuhlbrigge RC, Zurakowski D, Sundel RP: Clinical effects and safety of rituximab for treatment of refractory pediatric autoimmune diseases. J Pediatr; 2007 Apr;150(4):376-82
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  • [Title] Clinical effects and safety of rituximab for treatment of refractory pediatric autoimmune diseases.
  • OBJECTIVE: To evaluate the safety, tolerability, and clinical effects of rituximab, an anti-CD20 monoclonal antibody, in the treatment of severe pediatric autoimmune diseases.
  • With longer follow-up (median, 22 months), we found that 5 of 9 patients remained clinically stable after rituximab therapy, whereas 4 patients had recurrent or new features of their underlying autoimmune disorders requiring additional corticosteroids or other immunosuppressive medications.

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  • [CommentIn] J Pediatr. 2007 Apr;150(4):335-7 [17382106.001]
  • (PMID = 17382113.001).
  • [ISSN] 1097-6833
  • [Journal-full-title] The Journal of pediatrics
  • [ISO-abbreviation] J. Pediatr.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Immunoglobulins; 0 / Immunologic Factors; 4F4X42SYQ6 / Rituximab
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42. Brown JW, Ruzmetov M, Fiore AC, Rodefeld MD, Girod DA, Turrentine MW: Long-term results of apical aortic conduits in children with complex left ventricular outflow tract obstruction. Ann Thorac Surg; 2005 Dec;80(6):2301-8
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  • Fourteen surviving patients (56%) have undergone subsequent procedures (n = 18) from 5 months to 16 years postoperatively (mean, 6.9 years) because they developed a recurrent left ventricular-to-aortic gradient of 58 +/- 28 mm Hg (p < 0.002).
  • Since the early 1990s, the apical aortic conduit procedure has been largely replaced with the Ross or Ross-Konno procedure in our pediatric practice.

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  • (PMID = 16305893.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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43. Tareen BU, Bui D, McMahon DR, Nasrallah PF: Role of positional instillation of contrast cystography in the algorithm for evaluating children with confirmed pyelonephritis. Urology; 2006 May;67(5):1055-7; discussion 1058-9
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  • OBJECTIVES: To assess the utility of positional instillation of contrast (PIC) cystography in detecting vesicoureteral reflux (VUR) in patients with renal scarring from recurrent febrile urinary tract infections that standard voiding cystourethrography and nuclear cystogram imaging failed to reveal.
  • METHODS: Between June 2004 and November 2004, a total of 5 pediatric patients with recurrent febrile urinary tract infections and radiologic evidence of upper tract involvement were examined with PIC cystography.
  • CONCLUSIONS: The PIC cystogram should be integrated into the algorithm for diagnosing patients with recurrent febrile urinary tract infection, who do not exhibit VUR on standard imaging modalities.

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  • (PMID = 16698369.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / Contrast Media; 0 / Radiopharmaceuticals; 0 / deflux; 9004-61-9 / Hyaluronic Acid; DX1U2629QE / Succimer; K3R6ZDH4DU / Dextrans
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44. Zaki M, Badawi M, Al Mutari G, Ramadan D, Adul Rahman M: Acute pyelonephritis and renal scarring in Kuwaiti children: a follow-up study using 99mTc DMSA renal scintigraphy. Pediatr Nephrol; 2005 Aug;20(8):1116-9
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  • [Title] Acute pyelonephritis and renal scarring in Kuwaiti children: a follow-up study using 99mTc DMSA renal scintigraphy.
  • The aim of this study was to determine the prevalence of renal scarring in a group of Kuwaiti Arab children with their first documented acute pyelonephritis (APN).
  • Eighty-two Kuwaiti Arab children (10 males and 72 females) who had abnormal (99m)Tc DMSA renal scan findings of acute pyelonephritis were prospectively studied with the same imaging modality 6 months after treatment to identify those who developed renal scarring.
  • This work shows that APN is a serious cause for renal scarring in our patients, particularly if associated with other risk factors such as recurrent infections and the female sex.
  • [MeSH-minor] Acute Disease. Age Factors. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Male. Prospective Studies. Radionuclide Imaging. Vesico-Ureteral Reflux / diagnostic imaging

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  • (PMID = 15973531.001).
  • [ISSN] 0931-041X
  • [Journal-full-title] Pediatric nephrology (Berlin, Germany)
  • [ISO-abbreviation] Pediatr. Nephrol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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45. Morchi GS, Pietra B, Boucek MM, Chan KC: Interventional cardiac catheterization procedures in pediatric cardiac transplant patients: transplant surgery is not the end of the road. Catheter Cardiovasc Interv; 2008 Nov 15;72(6):831-6
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  • [Title] Interventional cardiac catheterization procedures in pediatric cardiac transplant patients: transplant surgery is not the end of the road.
  • OBJECTIVES: The objectives of this study are to report the spectrum of cardiac lesions in pediatric patients post-orthotopic heart transplantation (OHT), the characteristics of patients who develop these lesions, and the feasibility of transcatheter intervention in treating these lesions.
  • BACKGROUND: Indications for OHT in the pediatric population range from cardiomyopathy to complex congenital heart defects with and without prior palliation.
  • Fifteen were successfully treated with balloon angioplasty while one has recurrent supravalve aortic obstruction.
  • CONCLUSION: Anastomotic aortic arch and venous obstructive lesions should be sought following pediatric OHT as they occur in almost 20% of patients and can be successfully addressed using interventional techniques.

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18798241.001).
  • [ISSN] 1522-726X
  • [Journal-full-title] Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
  • [ISO-abbreviation] Catheter Cardiovasc Interv
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Nagayama Y, Tsubaki T, Sawada K, Taguchi K, Nakayama S, Toba T: Age and sex as factors of response to RSV infections among those with previous history of wheezing. Pediatr Allergy Immunol; 2006 Aug;17(5):376-81
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  • Although enhanced immune reaction caused by the respiratory syncytial virus (RSV) in allergen-sensitized animal model has been reported, RSV illnesses in children already sensitized or having recurrent wheezing episodes have not been completely studied.
  • Therefore, gender analysis in recurrent wheezing children with RSV infection can shed light on asthma pathogenesis.
  • We studied the clinical features and the laboratory data of RSV infections in children who had recurrent wheezing histories.
  • Above all, 3-yr-old children deteriorated clinically during acute RSV infection, accompanied by transient elevated C-reactive protein (CRP) and suppressed blood eosinophil counts.
  • Blood eosinophil counts at the acute illness were significantly higher in boys than girls aged 2 and 3< yr.

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  • (PMID = 16846457.001).
  • [ISSN] 0905-6157
  • [Journal-full-title] Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
  • [ISO-abbreviation] Pediatr Allergy Immunol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 37341-29-0 / Immunoglobulin E
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47. Menon G, Krishnakumar K, Nair S: Adult medulloblastoma: clinical profile and treatment results of 18 patients. J Clin Neurosci; 2008 Feb;15(2):122-6
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  • An attempt was made to identify the predictors of poor outcome and assess patterns of relapse and to compare these with pediatric medulloblastoma.
  • Two patients had re-operation for residual/recurrent lesions causing raised intracranial symptoms.

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  • (PMID = 18078755.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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48. Einsiedel HG, von Stackelberg A, Hartmann R, Fengler R, Schrappe M, Janka-Schaub G, Mann G, Hählen K, Göbel U, Klingebiel T, Ludwig WD, Henze G: Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: results of trial acute lymphoblastic leukemia-relapse study of the Berlin-Frankfurt-Münster Group 87. J Clin Oncol; 2005 Nov 1;23(31):7942-50
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  • [Title] Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: results of trial acute lymphoblastic leukemia-relapse study of the Berlin-Frankfurt-Münster Group 87.
  • PURPOSE: Approximately 20% of children with acute lymphoblastic leukemia (ALL) suffer a relapse, and their prognosis is unfavorable.
  • Between 1987 and 1990, the multicenter trial Acute Lymphoblastic Leukemia-Relapse Study of the Berlin-Frankfurt-Münster Group (ALL-REZ BFM) 87 was conducted to establish a uniform treatment for these children in Germany and Austria.
  • CONCLUSION: With the ALL-REZ BFM 87 protocol, more than one-third of patients may be regarded as cured from recurrent ALL with second complete remissions lasting more than 10 years.
  • [MeSH-major] Neoplasm Recurrence, Local / therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy. Salvage Therapy

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  • [ErratumIn] J Clin Oncol. 2008 May 1;26(13):2238
  • (PMID = 16258094.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] FTK8U1GZNX / Thioguanine; YL5FZ2Y5U1 / Methotrexate
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49. Attenello FJ, McGirt MJ, Garcés-Ambrossi GL, Chaichana KL, Carson B, Jallo GI: Suboccipital decompression for Chiari I malformation: outcome comparison of duraplasty with expanded polytetrafluoroethylene dural substitute versus pericranial autograft. Childs Nerv Syst; 2009 Feb;25(2):183-90
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  • OBJECTIVE: Treatment failure for Chiari decompression is frequently associated with scarring, intradural adhesions, and recurrent loss of hindbrain space.
  • (1) recurrent loss of dorsal hindbrain cerebrospinal fluid (CSF) space/CSF flow(cine-MR) at duraplasty site, (2) pseudomeningocele, or (3) syringomyelia improvement.

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  • (PMID = 18769929.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 9002-84-0 / Polytetrafluoroethylene
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50. Al-Salem AH: Congenital hernia of Morgagni in infants and children. J Pediatr Surg; 2007 Sep;42(9):1539-43
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  • Commonly, it is diagnosed during childhood but can remain asymptomatic till adulthood.
  • In the pediatric age group, the presentation is usually vague and nonspecific leading to delay in diagnosis.
  • Sixteen of them (80%) presented with recurrent chest infection, which most of them had had since early infancy.
  • Commonly, the presentation in the pediatric age group is that of recurrent chest infection and rarely with gastrointestinal symptoms.

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  • (PMID = 17848245.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Schwentner C, Oswald J, Lunacek A, Deibl M, Bartsch G, Radmayr C: Optimizing the outcome of microsurgical subinguinal varicocelectomy using isosulfan blue: a prospective randomized trial. J Urol; 2006 Mar;175(3 Pt 1):1049-52
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  • There were 2 patients in each group who reported ongoing pain, and 1 in each presented with recurrent varicocele.

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  • [CommentIn] J Urol. 2006 Mar;175(3 Pt 1):818-9 [16469559.001]
  • [CommentIn] Nat Clin Pract Urol. 2006 Sep;3(9):476-7 [16964188.001]
  • [ErratumIn] J Urol. 2008 Jul;180(1):415
  • (PMID = 16469616.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Rosaniline Dyes; 39N9K8S2A4 / iso-sulfan blue
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52. Hickson LJ, Gera M, Amer H, Iqbal CW, Moore TB, Milliner DS, Cosio FG, Larson TS, Stegall MD, Ishitani MB, Gloor JM, Griffin MD: Kidney transplantation for primary focal segmental glomerulosclerosis: outcomes and response to therapy for recurrence. Transplantation; 2009 Apr 27;87(8):1232-9
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  • RESULTS: Of these, 47% had recurrent FSGS compared with 8% of those not meeting strict criteria (P<0.001).
  • Graft survival was lower for recipients with primary FSGS compared with all others and inferior graft survival was attributable to recurrent FSGS.
  • Fourteen patients received PP preemptively (pre-KTx) or therapeutically (post-KTx) for recurrent disease.
  • Four pediatric patients additionally received anti-CD20 (rituximab) therapy.


53. Bruch SW, Hirschl RB, Coran AG: The diagnosis and management of recurrent tracheoesophageal fistulas. J Pediatr Surg; 2010 Feb;45(2):337-40
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  • [Title] The diagnosis and management of recurrent tracheoesophageal fistulas.
  • PURPOSE: This review provides a blueprint to deal with the diagnosis and management of recurrent tracheoesophageal fistulas.
  • METHODS: A retrospective review over 27 years found 26 recurrent tracheoesophageal fistulas.
  • RESULTS: In this cohort of 26 patients, 18 had a leak after their primary operation; and 22 had respiratory symptoms leading to the discovery of the recurrent fistula.
  • Postoperative complications included 7 anastamotic leaks, 4 strictures, and 3 recurrent fistulas.
  • CONCLUSION: This series, the largest to date, describes characteristics of recurrent tracheoesophageal fistulas, including techniques to make the diagnosis and provide a secure closure of the fistula, and the long-term outcomes of these patients.

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  • [Copyright] Copyright 2010. Published by Elsevier Inc.
  • (PMID = 20152347.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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54. Bentdal YE, Håberg SE, Karevold G, Stigum H, Kvaerner KJ, Nafstad P: Birth characteristics and acute otitis media in early life. Int J Pediatr Otorhinolaryngol; 2010 Feb;74(2):168-72
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  • [Title] Birth characteristics and acute otitis media in early life.
  • OBJECTIVE: To assess whether preterm birth and low birth weight were associated with single and recurrent episodes of acute otitis media (AOM) the first 18 months of life.
  • RESULTS: Preterm birth was slightly associated with both single and recurrent episodes of AOM the first 18 months of age.
  • The adjusted relative risk (aRR) for having any episode of AOM was 1.37, 95%CI (1.12-1.68) if born before week 33, and the aRR for having recurrent AOM was 1.34, 95%CI (1.01-1.77) if born in weeks 33-36 (reference group: >or=37 weeks).
  • [MeSH-minor] Acute Disease. Adult. Female. Humans. Infant. Infant, Newborn. Infant, Premature. Male. Pregnancy. Prevalence. Registries. Respiratory Tract Infections. Surveys and Questionnaires

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  • [Copyright] Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19959246.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Ireland
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55. Ulinski T: Recurrence of focal segmental glomerulosclerosis after kidney transplantation: strategies and outcome. Curr Opin Organ Transplant; 2010 Oct;15(5):628-32
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  • PURPOSE OF REVIEW: Steroid-resistant nephrotic syndrome/focal segmental glomerulonephritis (FSGS) is the primary renal disease in approximately 10% of pediatric patients receiving a renal allograft.
  • SUMMARY: No controlled studies have been performed yet to address the management of recurrent FSGS posttransplant.


56. Son MB, Sundel RP: Musculoskeletal causes of pediatric chest pain. Pediatr Clin North Am; 2010 Dec;57(6):1385-95
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  • [Title] Musculoskeletal causes of pediatric chest pain.
  • Causes range from the common, such as costochondritis, to the rare, such as chronic recurrent multifocal osteomyelitis.
  • Thus, efficient and accurate identification of the cause of pediatric chest pain by a thorough history and physical examination is important to minimize the disruption it may cause.

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21111123.001).
  • [ISSN] 1557-8240
  • [Journal-full-title] Pediatric clinics of North America
  • [ISO-abbreviation] Pediatr. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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57. Hoe FM, Charron M, Moshang T Jr: Use of the recombinant human TSH stimulated thyroglobulin level and diagnostic whole body scan in children with differentiated thyroid carcinoma. J Pediatr Endocrinol Metab; 2006 Jan;19(1):25-30
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  • Two children had recurrent disease: one had a negative DxWBS and Tg of 15 ng/ml; and one had a positive DxWBS and no Tg measured.

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  • (PMID = 16509525.001).
  • [ISSN] 0334-018X
  • [Journal-full-title] Journal of pediatric endocrinology & metabolism : JPEM
  • [ISO-abbreviation] J. Pediatr. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Iodine Radioisotopes; 0 / Recombinant Proteins; 9002-71-5 / Thyrotropin; 9010-34-8 / Thyroglobulin
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58. Menon S, Hari P, Bagga A: Beneficial effects of rituximab therapy for systemic lupus erythematosus. Indian J Pediatr; 2007 Jan;74(1):79-82
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  • We report an 11-yr-old girl with systemic lupus erythematosus (SLE) with recurrent flares of skin and systemic manifestations, which were poorly controlled with conventional therapy.

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  • (PMID = 17264461.001).
  • [ISSN] 0973-7693
  • [Journal-full-title] Indian journal of pediatrics
  • [ISO-abbreviation] Indian J Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Immunologic Factors; 4F4X42SYQ6 / Rituximab
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59. Liu AK, Foreman NK, Gaspar LE, Trinidad E, Handler MH: Maximally safe resection followed by hypofractionated re-irradiation for locally recurrent ependymoma in children. Pediatr Blood Cancer; 2009 Jul;52(7):804-7
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  • [Title] Maximally safe resection followed by hypofractionated re-irradiation for locally recurrent ependymoma in children.
  • PROCEDURE: We performed a review of the experience at the Children's Hospital in Denver and at the Department of Radiation Oncology at the University of Colorado Denver from 1995 to 2008 with hypofractionated re-irradiation after maximally safe resection in children with locally recurrent ependymoma.
  • RESULTS: Six children with locally recurrent ependymoma were seen in that time period.
  • CONCLUSIONS: Hypofractionated re-irradiation after resection for locally recurrent ependymoma is well tolerated.


60. Stone JJ, Rozzelle CJ: Retethering of sectioned fibrolipomatous filum terminale in an adult: case report and review of the literature. Spine J; 2010 Aug;10(8):e1-4
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  • BACKGROUND CONTEXT: Recurrent tethering of the spinal cord is a rare late complication after sectioning of a fibrolipomatous filum terminale that has only been reported in two pediatric cases.
  • PURPOSE: To report adult-onset recurrent tethering of the spinal cord after surgical sectioning of a fibrolipomatous filum terminale and review the literature in an attempt to identify similar cases.
  • CONCLUSIONS: Sectioning of both abnormal and apparently normal fila has become a relatively common procedure in pediatric neurosurgery.

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20650405.001).
  • [ISSN] 1878-1632
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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61. Homan M, Baldassano RN, Mamula P: Managing complicated Crohn's disease in children and adolescents. Nat Clin Pract Gastroenterol Hepatol; 2005 Dec;2(12):572-9
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  • The natural history of Crohn's disease is characterized by recurrent exacerbations.
  • A small, but significant, number of pediatric patients with Crohn's disease are resistant to standard medical therapies.
  • The goal of therapy in pediatric patients is not only to achieve and maintain clinical remission, but also to promote growth, development and improve quality of life.
  • The standard therapy for pediatric patients with Crohn's disease consists of 5-aminosalicylic-acid compounds, antibiotics and enteral nutrition.

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  • (PMID = 16327836.001).
  • [ISSN] 1743-4378
  • [Journal-full-title] Nature clinical practice. Gastroenterology & hepatology
  • [ISO-abbreviation] Nat Clin Pract Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Gastrointestinal Agents; 0 / Immunosuppressive Agents; 0 / Tumor Necrosis Factor-alpha; B72HH48FLU / Infliximab
  • [Number-of-references] 76
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62. Bishay M, Short M, Shah K, Nagraj S, Arul S, Parikh D, Jawaheer G: Efficacy of video-assisted thoracoscopic surgery in managing childhood empyema: a large single-centre study. J Pediatr Surg; 2009 Feb;44(2):337-42
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  • [Title] Efficacy of video-assisted thoracoscopic surgery in managing childhood empyema: a large single-centre study.
  • BACKGROUND/PURPOSE: A randomised controlled trial evaluating the role of video-assisted thoracoscopic surgery (VATS) in childhood empyema reported a failure rate of 16.6%.
  • There were 8 (7%) treatment failures: 5 conversions to thoracotomy and 3 recurrent empyemas.
  • CONCLUSION: Video-assisted thoracoscopic surgery has a better outcome in childhood empyema than reported in a recent randomised trial and it has an important role in the management of this condition.

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  • (PMID = 19231530.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. von Neuhoff C, Reinhardt D, Sander A, Zimmermann M, Bradtke J, Betts DR, Zemanova Z, Stary J, Bourquin JP, Haas OA, Dworzak MN, Creutzig U: Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98. J Clin Oncol; 2010 Jun 1;28(16):2682-9
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  • [Title] Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.
  • PURPOSE: Because cytogenetic data are essential for risk stratification of childhood acute myeloid leukemia (AML), the impact of chromosomal aberrations is crucial.
  • CONCLUSION: Because the prognostic value of rare recurrent chromosomal aberrations still has to be elucidated, these data will contribute to future risk stratification for the treatment of pediatric AML.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Chromosome Aberrations. Chromosomes, Human, Pair 21. Chromosomes, Human, Pair 8. Leukemia, Myeloid, Acute / genetics. Leukemia, Myeloid, Acute / therapy

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  • (PMID = 20439630.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 04079A1RDZ / Cytarabine; 6PLQ3CP4P3 / Etoposide; ZRP63D75JW / Idarubicin; ICE protocol 4
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64. Styczynski J, Gil L, Derwich K, Wachowiak J, Balwierz W, Badowska W, Krawczuk-Rybak M, Matysiak M, Wieczorek M, Balcerska A, Sonta-Jakimczyk D, Stefaniak J, Kowalczyk J, Urasinski T, Sobol G, Komarnicki M, Wysocki M: Comparison of clofarabine activity in childhood and adult acute leukemia: individual tumor response study. Anticancer Res; 2009 May;29(5):1643-50
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  • [Title] Comparison of clofarabine activity in childhood and adult acute leukemia: individual tumor response study.
  • The aim of the study was the analysis of ex vivo activity of clofarabine and 14 other anticancer drugs in pediatric and adult acute lymphoblastic (ALL) and myeloid (AML) leukemia.
  • PATIENTS AND METHODS: The ex vivo drug resistance profile was analyzed in 282 patients, including 201 children with ALL de novo, 24 children with relapsed ALL, 25 children with AML de novo and 32 adults with AML.
  • Its activity in acute myeloid leukemia was independent of patient age.
  • No significant differences in drug resistance to clofarabine between pediatric age-based subgroups of ALL were detected, while it was observed for most of other drugs.
  • An activity of clofarabine in relapsed pediatric ALL patients was as good as in newly-diagnosed ones.
  • CONCLUSION: In comparison to childhood acute lymphoblastic leukemia, lack of differences in ex vivo activity gives rationale for use of clofarabine in refractory and relapsed pediatric and adult patients with acute myeloid leukemia.
  • [MeSH-major] Adenine Nucleotides / therapeutic use. Antineoplastic Agents / therapeutic use. Arabinonucleosides / therapeutic use. Leukemia / drug therapy
  • [MeSH-minor] Acute Disease. Adolescent. Adult. Child. Child, Preschool. Humans. Infant. Middle Aged. Treatment Outcome. Young Adult

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  • (PMID = 19443380.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Adenine Nucleotides; 0 / Antineoplastic Agents; 0 / Arabinonucleosides; 762RDY0Y2H / clofarabine
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65. Stankovic M: Follow-up of cholesteatoma surgery: open versus closed tympanoplasty. ORL J Otorhinolaryngol Relat Spec; 2007;69(5):299-305
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  • Recurrent cholesteatomas were more than twice as frequent in children (19.0%) as in adults (9.4%).
  • In one fourth of pediatric cholesteatoma reoperations, conversion to open tympanoplasty was done.
  • Retraction and recurrent disease were present in about 10% of attic and sinus cholesteatomas, and in 15.5% of tensa cholesteatomas.
  • Retraction pockets, recurrent cholesteatomas and reoperations are twice as frequent in the pediatric group as in adults.

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  • [Copyright] (c) 2007 S. Karger AG, Basel.
  • (PMID = 17630475.001).
  • [ISSN] 1423-0275
  • [Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties
  • [ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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66. Jia H, Huang Q, Wu H, Zhang Z, Wang Z, Li Y: [The selection of surgical technique for cholesteatoma in pediatric patients]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Apr;23(7):296-7, 301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The selection of surgical technique for cholesteatoma in pediatric patients].
  • OBJECTIVE: To discuss the surgical treatments and results for cholesteatoma in pediatric patients.
  • METHOD: A retrospective analysis of 25 cases of cholesteatoma in pediatric patients.
  • RESULT: During the follow-up, 24 patients were cured in first-stage surgery, no recurrent cholesteatoma was observed, no observed complications occurred after surgery.

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  • (PMID = 19670605.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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67. Huh WW, Beverly Raney R: Orbital metastasis in patients with rhabdomyosarcoma: case series and review of the literature. J Pediatr Hematol Oncol; 2006 Oct;28(10):684-7
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  • We present 3 cases of children who developed recurrent rhabdomyosarcoma with metastases to the orbit and review the medical literature.

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  • (PMID = 17023831.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 18
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68. Corradin L, Fanton E: [A survey and childhood deafness in a neonatology unit of Caritas Baby Hospital in Bethlehem]. Assist Inferm Ric; 2008 Apr-Jun;27(2):85-90
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  • [Title] [A survey and childhood deafness in a neonatology unit of Caritas Baby Hospital in Bethlehem].
  • AIM: The prevalence of deafness in a pediatric hospital Caritas Baby Hospital in Bethlehem was described.
  • The most recurrent diagnoses were jaundice, potential sepsis and prematurity.


69. Mackall CL, Rhee EH, Read EJ, Khuu HM, Leitman SF, Bernstein D, Tesso M, Long LM, Grindler D, Merino M, Kopp W, Tsokos M, Berzofsky JA, Helman LJ: A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas. Clin Cancer Res; 2008 Aug 1;14(15):4850-8
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  • [Title] A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas.
  • PURPOSE: Patients with metastatic or recurrent Ewing's sarcoma family of tumors and alveolar rhabdomyosarcoma have <25% 5-year survival in most studies.
  • EXPERIMENTAL DESIGN: Fifty-two patients with translocation positive, recurrent, or metastatic Ewing's sarcoma family of tumors or alveolar rhabdomyosarcoma underwent prechemotherapy cell harvest via apheresis for potential receipt of immunotherapy.


70. Chung BJ, Akst LM, Koltai PJ: 3.5-Year follow-up of intralesional cidofovir protocol for pediatric recurrent respiratory papillomatosis. Int J Pediatr Otorhinolaryngol; 2006 Nov;70(11):1911-7
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  • [Title] 3.5-Year follow-up of intralesional cidofovir protocol for pediatric recurrent respiratory papillomatosis.
  • OBJECTIVES: Intralesional injection of cidofovir has been described as an adjunctive treatment for pediatric recurrent respiratory papillomatosis (RRP).
  • METHODS: Eleven pediatric patients originally treated with a standardized stepped-dose protocol of intralesional cidofovir for RRP were followed for an extended observational period.
  • Two patients initially achieved remission but have subsequently required additional treatment for recurrent disease.

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  • (PMID = 16919339.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Organophosphonates; 8J337D1HZY / Cytosine; JIL713Q00N / cidofovir
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71. Gargiulo G, Pace Napoleone C, Angeli E, Oppido G: Neonatal coarctation repair using extended end-to-end anastomosis. Multimed Man Cardiothorac Surg; 2008 Jan 1;2008(328):mmcts.2007.002691
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  • There is a wide variety of techniques currently proposed to repair neonatal coarctation, all reported associated with very low operative mortality, nevertheless which one would be the best technique in terms of minimal rate of residual or recurrent obstruction or late complications is still under debate.

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  • (PMID = 24415449.001).
  • [Journal-full-title] Multimedia manual of cardiothoracic surgery : MMCTS
  • [ISO-abbreviation] Multimed Man Cardiothorac Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
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72. Olsen LH, Jørgensen TM: Robotically assisted retroperitoneoscopic heminephrectomy in children: initial clinical results. J Pediatr Urol; 2005 Apr;1(2):101-4
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  • One patient had the ureteric stump removed due to recurrent infections.

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  • (PMID = 18947545.001).
  • [ISSN] 1873-4898
  • [Journal-full-title] Journal of pediatric urology
  • [ISO-abbreviation] J Pediatr Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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73. Postovsky S, Barzilai M, Meller I, Kollander Y, Futerman B, Ben Arush MW: Does regular follow-up influence the survival of patients with sarcoma after recurrence? The Miri Shitrit pediatric oncology department experience. J Pediatr Hematol Oncol; 2008 Mar;30(3):189-95
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does regular follow-up influence the survival of patients with sarcoma after recurrence? The Miri Shitrit pediatric oncology department experience.
  • Despite comprehensive management of pediatric sarcomas, only 60% to 70% of children become long-term survivors.
  • This study was undertaken to evaluate whether regular follow-up improves overall survival of children with recurrent sarcomas.
  • The medical charts of 107 children diagnosed with soft tissue and bone sarcomas were reviewed, of whom 29 relapsed.
  • (3) other diagnostic and treatment approaches are needed to improve the survival of children with recurrent sarcomas.

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  • (PMID = 18376279.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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74. Kearney SL, Dahlberg SE, Levy DE, Voss SD, Sallan SE, Silverman LB: Clinical course and outcome in children with acute lymphoblastic leukemia and asparaginase-associated pancreatitis. Pediatr Blood Cancer; 2009 Aug;53(2):162-7
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  • [Title] Clinical course and outcome in children with acute lymphoblastic leukemia and asparaginase-associated pancreatitis.
  • BACKGROUND: Asparaginase, an agent used in the treatment of acute lymphoblastic leukemia (ALL), is associated with the development of pancreatitis.
  • CONCLUSION: Asparaginase-associated pancreatitis was more common in older children, and caused significant acute morbidity.
  • Re-treatment with asparaginase after an episode of pancreatitis was associated with a high risk of recurrent pancreatitis.

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
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  • (PMID = 19405141.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA068484-13; United States / NCI NIH HHS / CA / P01 CA068484-13; United States / NCI NIH HHS / CA / P01 CA068484-139001; United States / NCI NIH HHS / CA / CA068484-139001; United States / NCI NIH HHS / CA / P01 CA068484; United States / NCI NIH HHS / CA / 5P01CA68484
  • [Publication-type] Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; EC 3.5.1.1 / Asparaginase
  • [Other-IDs] NLM/ NIHMS110197; NLM/ PMC2721691
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75. Urschitz MS, Eitner S, Wolff J, Guenther A, Urschitz-Duprat PM, Schlaud M, Poets CF: Risk factors for sleep-related hypoxia in primary school children. Pediatr Pulmonol; 2007 Sep;42(9):805-12
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  • We aimed to identify demographic and clinical factors associated with mild (nadir arterial oxygen saturation 91-93%), moderate (nadir arterial oxygen saturation <or=90%), and recurrent (oxygen desaturation index > 3.9) sleep-related hypoxia in children.
  • In multiple regression analysis, (i) overweight (OR, 95% CI: 2.7, 1.7-4.3) and a history of respiratory allergy (1.7, 1.1-2.7) were independent risk factors for mild sleep-related hypoxia, (ii) overweight (3.2, 1.7-5.8), a history of respiratory allergy (2.4, 1.4-4.4), and household smoking >10 cigarettes/day (1.8, 1.1-2.8) were independent risk factors for moderate sleep-related hypoxia, and (iii) overweight (2.3, 1.04-5.3), a history of respiratory allergy (2.5, 1.2-5.1), and a current respiratory tract infection (4.4, 2.0-9.8), were independent risk factors for recurrent sleep-related hypoxia.
  • Our data suggest that overweight, passive smoking, respiratory allergies, and acute lung disease may independently contribute to sleep-related hypoxia in children.

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17659603.001).
  • [ISSN] 8755-6863
  • [Journal-full-title] Pediatric pulmonology
  • [ISO-abbreviation] Pediatr. Pulmonol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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76. Tosello V, Mansour MR, Barnes K, Paganin M, Sulis ML, Jenkinson S, Allen CG, Gale RE, Linch DC, Palomero T, Real P, Murty V, Yao X, Richards SM, Goldstone A, Rowe J, Basso G, Wiernik PH, Paietta E, Pieters R, Horstmann M, Meijerink JP, Ferrando AA: WT1 mutations in T-ALL. Blood; 2009 Jul 30;114(5):1038-45
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  • The molecular mechanisms involved in disease progression and relapse in T-cell acute lymphoblastic leukemia (T-ALL) are poorly understood.
  • We used single nucleotide polymorphism array analysis to analyze paired diagnostic and relapsed T-ALL samples to identify recurrent genetic alterations in T-ALL.
  • This analysis showed that diagnosis and relapsed cases have common genetic alterations, but also that relapsed samples frequently lose chromosomal markers present at diagnosis, suggesting that relapsed T-ALL emerges from an ancestral clone different from the major leukemic population at diagnosis.
  • Subsequent analysis showed WT1 mutations in 28 of 211 (13.2%) of pediatric and 10 of 85 (11.7%) of adult T-ALL cases.
  • Survival analysis demonstrated that WT1 mutations do not confer adverse prognosis in pediatric and adult T-ALL.
  • Overall, these results identify the presence of WT1 mutations as a recurrent genetic alteration in T-ALL.
  • [MeSH-major] Genes, Wilms Tumor. Mutation. Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics

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  • (PMID = 19494353.001).
  • [ISSN] 1528-0020
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] eng
  • [Databank-accession-numbers] GEO/ GSE15931
  • [Grant] United States / NCI NIH HHS / CA / CA114737; United Kingdom / Medical Research Council / / MC/ U137686856; United States / NCI NIH HHS / CA / R01 CA129382; United Kingdom / Medical Research Council / / ; United States / NCI NIH HHS / CA / CA02111; United Kingdom / Medical Research Council / / G0500389; United States / NCI NIH HHS / CA / R01CA120196; United States / NCI NIH HHS / CA / R01CA129382; United States / NCI NIH HHS / CA / R01 CA120196; United States / NCI NIH HHS / CA / U24 CA114737; United States / NCI NIH HHS / CA / R01 CA120196-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Neoplasm Proteins; 0 / WT1 Proteins
  • [Other-IDs] NLM/ PMC2721784
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77. Hassani A, Ponvert C, Karila C, Le Bourgeois M, De Blic J, Scheinmann P: Hypersensitivity to cyclooxygenase inhibitory drugs in children: a study of 164 cases. Eur J Dermatol; 2008 Sep-Oct;18(5):561-5
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  • Anaphylaxis, immediate and accelerated reactions, atopy, older age and chronic/recurrent urticaria were risk factors for hypersensitivity and/or cross-reactivity between ASA, ibuprofen and paracetamol.

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  • (PMID = 18693161.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Cyclooxygenase Inhibitors; 362O9ITL9D / Acetaminophen; R16CO5Y76E / Aspirin; WK2XYI10QM / Ibuprofen
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78. Miller AD, Young MC, DeMott MC, Ly BT, Clark RF: Recurrent coagulopathy and thrombocytopenia in children treated with crotalidae polyvalent immune fab: a case series. Pediatr Emerg Care; 2010 Aug;26(8):576-82
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  • [Title] Recurrent coagulopathy and thrombocytopenia in children treated with crotalidae polyvalent immune fab: a case series.
  • OBJECTIVES: Recurrent signs and symptoms after initial treatment and control of coagulopathy and thrombocytopenia after American pit viper (crotaline) envenomations have been previously described in patients treated with Crotalidae polyvalent immune Fab antivenom (FabAV).
  • The significance and necessity of treatment of these recurrent abnormalities are uncertain.
  • Our goal was to further characterize recurrent coagulopathy or thrombocytopenia in pediatric patients.
  • METHODS: All cases presenting to our Toxicology Consult Service, which covers 6 hospitals in a metropolitan area, from May 2007 to April 2008 with recurrent coagulopathy after initial control with FabAV were included and retrospectively reviewed.
  • RESULTS: Four cases of pediatric patients are presented who presented with recurrent coagulopathy and/or thrombocytopenia after initial control with FabAV.

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  • (PMID = 20693856.001).
  • [ISSN] 1535-1815
  • [Journal-full-title] Pediatric emergency care
  • [ISO-abbreviation] Pediatr Emerg Care
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antivenins; 0 / Crotalid Venoms; 0 / Crotalidae Polyvalent immune Fab; 0 / Immunoglobulin Fab Fragments; 0 / Immunoglobulin Fragments
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79. Thomas JC, DeMarco RT, Donohoe JM, Adams MC, Pope JC 4th, Brock JW 3rd: Management of the failed pyeloplasty: a contemporary review. J Urol; 2005 Dec;174(6):2363-6
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  • PURPOSE: We reviewed our experience with open dismembered pyeloplasty, with specific focus on the presentation and management of failed pyeloplasty in the pediatric population.
  • The patients were followed postoperatively with serial ultrasounds, with renograms reserved for those patients with prolonged, persistent or worsening hydronephrosis, or recurrent symptoms during followup.

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  • (PMID = 16280844.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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80. Pokushalov E, Romanov A, Turov A, Artyomenko S, Shirokova N, Karaskov A: Percutaneous epicardial ablation of ventricular tachycardia after failure of endocardial approach in the pediatric population with arrhythmogenic right ventricular dysplasia. Heart Rhythm; 2010 Oct;7(10):1406-10
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  • [Title] Percutaneous epicardial ablation of ventricular tachycardia after failure of endocardial approach in the pediatric population with arrhythmogenic right ventricular dysplasia.
  • OBJECTIVE: This study sought to report the feasibility and results of epicardial VT ablation in a pediatric population of ARVD patients in whom endocardial ablation was unsuccessful.
  • METHODS: Seventeen ARVD pediatric patients (mean age 14 ± 4 years) in whom a percutaneous epicardial radiofrequency ablation of VT was attempted were included in this retrospective analysis.
  • CONCLUSION: Percutaneous epicardial catheter ablation is feasible and relatively safe in pediatric ARVD patients with recurrent VT in whom conventional endocardial ablation failed.

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  • [Copyright] Copyright © 2010 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20601157.001).
  • [ISSN] 1556-3871
  • [Journal-full-title] Heart rhythm
  • [ISO-abbreviation] Heart Rhythm
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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81. Kapoor V, Lodha R, Agarwala S: Superior mediastinal syndrome with Rowland-Payne syndrome: an unusual presentation of cervico-mediastinal neuroblastoma. Pediatr Blood Cancer; 2005 Mar;44(3):280-2
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  • He had an unusual constellation of findings not previously reported in neuroblastoma: Horner syndrome, phrenic nerve palsy, and palsy of the ipsilateral recurrent laryngeal nerve.


82. Chen EY, Inglis AF, Ou H, Perkins JA, Sie KC, Chiara J, Manning SC: Endoscopic electrocauterization of pyriform fossa sinus tracts as definitive treatment. Int J Pediatr Otorhinolaryngol; 2009 Aug;73(8):1151-6
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  • RESULTS: All nine patients presented with recurrent left or midline neck masses or abscesses.
  • Two patients (22%) had recurrent left neck abscesses after endoscopic treatment; these patients ultimately underwent excision of sinus tract with left thyroid lobectomy without complications or further recurrences.

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  • (PMID = 19481267.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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83. Lødrup Carlsen KC, Løvik M, Granum B, Mowinckel P, Carlsen KH: Soluble CD14 at 2 yr of age: gender-related effects of tobacco smoke exposure, recurrent infections and atopic diseases. Pediatr Allergy Immunol; 2006 Jun;17(4):304-12
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  • [Title] Soluble CD14 at 2 yr of age: gender-related effects of tobacco smoke exposure, recurrent infections and atopic diseases.
  • In the nested case-control study of the birth cohort studies 'Environment and Childhood Asthma study in Oslo' 411 children selected with recurrent bronchial obstruction (rBO) (n=241) and no bronchial obstruction (n=170) by 2 yr were investigated with skin prick test and structured parental interview at age 2 yr.
  • The sCD14 was significantly reduced among girls exposed to antenatal maternal smoking and with parental asthma, after adjusting for age, parental rhino-conjunctivitis, pet keeping and childhood infections.
  • Recurrent otitis media (OM) increased and common colds significantly decreased sCD14 levels in girls.
  • We report novel gender-related effects of sCD14 in early life and suggest that gender, tobacco smoke exposure, age and middle ear disease in particular should be accounted for when assessing the role of sCD14 in childhood allergic diseases.

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  • (PMID = 16771785.001).
  • [ISSN] 0905-6157
  • [Journal-full-title] Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
  • [ISO-abbreviation] Pediatr Allergy Immunol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD14; 0 / Tobacco Smoke Pollution; 37341-29-0 / Immunoglobulin E; EC 1.11.1.7 / Peroxidase; EC 3.1.27.- / Eosinophil Cationic Protein
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84. Schaad UB: OM-85 BV, an immunostimulant in pediatric recurrent respiratory tract infections: a systematic review. World J Pediatr; 2010 Feb;6(1):5-12
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  • [Title] OM-85 BV, an immunostimulant in pediatric recurrent respiratory tract infections: a systematic review.
  • BACKGROUND: This study was conducted to assess the efficacy of OM-85 BV (Broncho-Vaxom) in the prevention of pediatric recurrent respiratory tract infections (RTIs).
  • Available evidence suggests that defining recurrent RTIs as >or=3 infections per fall-winter semester is both medically and epidemiologically justified.
  • Of the patients in the OM-85 BV treated population (n=435), 32% had recurrent RTIs (that is, >or=3 RTIs/6 months) vs. 58.2% in the placebo treated population (n=416; P<0.001).
  • CONCLUSIONS: This meta-analysis shows, as observed in several individual trials, that the population treated with OM-85 BV had significantly and consistently fewer cases of recurrent RTIs.
  • The data suggest that the effect is greater in patients at increased risk of recurrent RTIs.

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  • (PMID = 20143206.001).
  • [ISSN] 1867-0687
  • [Journal-full-title] World journal of pediatrics : WJP
  • [ISO-abbreviation] World J Pediatr
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Adjuvants, Immunologic; 0 / Broncho-Vaxom; 0 / Cell Extracts
  • [Number-of-references] 44
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85. Cannady SB, Chung BJ, Hirose K, Garabedian N, Van Den Abbeele T, Koltai PJ: Surgical management of cervical ganglioneuromas in children. Int J Pediatr Otorhinolaryngol; 2006 Feb;70(2):287-94
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  • No synchronous tumors were noted, nor has a recurrent tumor been observed to this point.

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  • (PMID = 16102846.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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86. Boykin RE, Ogunseinde B, McFeely ED, Nasreddine A, Kocher MS: Preliminary results of calcaneofibular ligament transfer for recurrent peroneal subluxation in children and adolescents. J Pediatr Orthop; 2010 Dec;30(8):899-903
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  • [Title] Preliminary results of calcaneofibular ligament transfer for recurrent peroneal subluxation in children and adolescents.
  • BACKGROUND: Subluxation of the peroneal tendons over the lateral malleolus is an uncommon condition in both pediatric and adult populations.
  • Various operative techniques have been reported earlier, but little data exists regarding surgical management and outcome in a pediatric and adolescent population with open physes.
  • METHODS: A retrospective review of patients presenting to our institution over a 5-year period yielded 9 cases of recurrent peroneal subluxation refractory to nonoperative management in 7 children or adolescents (mean age 12 y).
  • CONCLUSIONS: Peroneal subluxation is an uncommon condition in pediatric and adolescent athletes.
  • CFL transfer over the peroneal tendons should be considered as it provides excellent stability, a low rate of recurrent subluxation, and good functional outcomes without risk of injury to the distal fibular physis which can occur with distal fibular osteotomy or groove deepening procedures.

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  • (PMID = 21102220.001).
  • [ISSN] 1539-2570
  • [Journal-full-title] Journal of pediatric orthopedics
  • [ISO-abbreviation] J Pediatr Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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87. Stephens J, Singh A, Hughes J, Goswami T, Ghufoor K, Sandhu G: A prospective multi-centre randomised controlled trial comparing PlasmaKnife with bipolar dissection tonsillectomy: evaluating an emerging technology. Int J Pediatr Otorhinolaryngol; 2009 Apr;73(4):597-601
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  • The participants were 100 patients aged 2-16 years with recurrent tonsillitis or obstructive adenotonsillar hypertrophy awaiting a tonsillectomy were recruited in to the study.

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  • (PMID = 19157574.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Randomized Controlled Trial
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Analgesics
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88. Heng JL, Chen YC, Quah TC, Liu TC, Yeoh AE: Dedicated cytogenetics factor is critical for improving karyotyping results for childhood leukaemias - experience in the National University Hospital, Singapore 1989-2006. Ann Acad Med Singapore; 2010 Feb;39(2):102-6
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  • [Title] Dedicated cytogenetics factor is critical for improving karyotyping results for childhood leukaemias - experience in the National University Hospital, Singapore 1989-2006.
  • INTRODUCTION: Childhood leukaemia accounts for more than 40% of new childhood cancer cases.
  • Unfortunately, karyotyping of childhood leukaemia is difficult, laborious and often unsuccessful.
  • Among them, 369 newly diagnosed and relapsed childhood acute leukaemia cases [281 acute lymphoblastic leukaemia (ALL) and 88 acute myeloid leukaemia (AML)] have been diagnosed at NUH.
  • [MeSH-major] Cytogenetic Analysis / methods. Leukemia, Myeloid, Acute / diagnosis. Leukemia, Myeloid, Acute / genetics

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  • (PMID = 20237730.001).
  • [ISSN] 0304-4602
  • [Journal-full-title] Annals of the Academy of Medicine, Singapore
  • [ISO-abbreviation] Ann. Acad. Med. Singap.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
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89. Cook SP: Candidate's Thesis: Laryngotracheal separation in neurologically impaired children: long-term results. Laryngoscope; 2009 Feb;119(2):390-5
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  • OBJECTIVES: Fifty-six consecutive neurologically impaired pediatric children underwent laryngotracheal separation (LTS) for acute recurrent and chronic aspiration in the last 18 years.

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  • (PMID = 19160406.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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90. Huppke P, Blüthner M, Bauer O, Stark W, Reinhardt K, Huppke B, Gärtner J: Neuromyelitis optica and NMO-IgG in European pediatric patients. Neurology; 2010 Nov 9;75(19):1740-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neuromyelitis optica and NMO-IgG in European pediatric patients.
  • OBJECTIVE: Neuromyelitis optica (NMO) is currently considered a severe relapsing CNS demyelinating disorder that is associated with aquaporin-4 immunoglobulin G (NMO-IgG) while in earlier reports of NMO in childhood it has been described as a benign and monophasic disorder.
  • This study was performed to analyze the prevalence and the clinical course of NMO in a European pediatric cohort of patients with demyelinating CNS disorders.
  • METHODS: A cohort study was performed evaluating 118 pediatric patients presenting at the Center for Multiple Sclerosis in Childhood and Adolescents, Göttingen, Germany, with demyelinating CNS disorders between 2000 and 2009.
  • RESULTS: The majority of patients (94%) were diagnosed with remitting recurrent multiple sclerosis.
  • In the European pediatric population, NMO is very rare and in the majority of patients not associated with NMO-IgG.

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  • (PMID = 21060098.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / AQP4 protein, human; 0 / Aquaporin 4; 0 / Immunoglobulin G
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91. Liukkonen K, Virkkula P, Aronen ET, Kirjavainen T, Pitkäranta A: All snoring is not adenoids in young children. Int J Pediatr Otorhinolaryngol; 2008 Jun;72(6):879-84
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  • History of previous adenotonsillectomies (p<0.001), allergic rhinitis (p<0.001), recurrent respiratory infections (p<0.001), and otitis media (p<0.001) were more common among snorers than among occasional or never-snorers.

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  • (PMID = 18400311.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
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92. Cochard M, Clet J, Le L, Pillet P, Onrubia X, Guéron T, Faouzi M, Hofer M: PFAPA syndrome is not a sporadic disease. Rheumatology (Oxford); 2010 Oct;49(10):1984-7
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  • OBJECTIVES: To determine whether PFAPA (periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) patients have a positive family history (FH) for recurrent fever syndromes.
  • As controls, we interviewed a group of children without history of recurrent fever.
  • The FH for recurrent fever (without an infectious cause and recurring for at least half a year) was positive in 38/84 (45%), and was positive for PFAPA (diagnosis confirmed by a physician) in 10/84 (12%) of the PFAPA patients.
  • None of the healthy children had a positive FH for recurrent fever or PFAPA.
  • CONCLUSION: These data show that a significant percentage of PFAPA patients present a positive FH of recurrent fever and PFAPA.

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  • (PMID = 20601652.001).
  • [ISSN] 1462-0332
  • [Journal-full-title] Rheumatology (Oxford, England)
  • [ISO-abbreviation] Rheumatology (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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93. Al-Rashdan A, LeBlanc J, Sherman S, McHenry L, DeWitt J, Al-Haddad M: Role of endoscopic ultrasound for evaluating gastrointestinal tract disorders in pediatrics: a tertiary care center experience. J Pediatr Gastroenterol Nutr; 2010 Dec;51(6):718-22
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  • The clinical impact of EUS on the management of the pediatric population remains less clear.
  • This study evaluates the feasibility, safety, and applications of EUS ± FNA in pediatric GI tract disorders.
  • Retrospective chart review was conducted to document procedure indications, type of anesthesia used, EUS findings, final FNA cytology results, and clinical impact of EUS ± FNA on the subsequent management of pediatric patients.
  • The main indications for EUS were acute or recurrent pancreatitis, abdominal pain of suspected pancreatobiliary origin, suspected biliary obstruction, upper GI mucosal/submucosal lesions, and evaluation of pancreatic abnormalities seen on prior imaging.
  • CONCLUSIONS: EUS ± FNA is feasible and safe and makes a significant impact on most pediatric patients.

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  • (PMID = 20683206.001).
  • [ISSN] 1536-4801
  • [Journal-full-title] Journal of pediatric gastroenterology and nutrition
  • [ISO-abbreviation] J. Pediatr. Gastroenterol. Nutr.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hypnotics and Sedatives
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94. Kværner KJ, Kristiansen HA, Russell MB: Otitis media history, surgery and allergy in 60-year perspective: a population-based study. Int J Pediatr Otorhinolaryngol; 2010 Dec;74(12):1356-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: To assess the relationship between recurrent otitis media (OM), OM surgery and allergy in a 60-years perspective in the general population.
  • Main outcome measures were recurrent childhood OM, childhood myringotomy, ventilation tubes or adenoidectomy and lifetime allergy.
  • RESULTS: The prevalence of recurrent OM was 24.3% (n=4823) and OM surgery 12.4% (n=2499).
  • Recurrent OM and OM surgery was more common in respondents with allergy.
  • CONCLUSIONS: Despite a twofold increase in recurrent OM and OM surgery from 1925 to 1945, the proportion of OM and OM surgery have been stable since 1945.
  • Our findings suggest a shift in clinical practice, most likely indicating a change in surgery from acute infections to otitis media with effusion (OME).

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  • [Copyright] Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20934223.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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95. Suzuki T, Ohye RG, Devaney EJ, Ishizaka T, Nathan PN, Goldberg CS, Gomez CA, Bove EL: Selective management of the left ventricular outflow tract for repair of interrupted aortic arch with ventricular septal defect: management of left ventricular outflow tract obstruction. J Thorac Cardiovasc Surg; 2006 Apr;131(4):779-84
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  • Only 1 patient had recurrent muscular left ventricular outflow tract obstruction.
  • Tailored to the degree of subaortic narrowing, resection or incision of the infundibular septum at the time of primary repair was very effective in preventing or prolonging the interval to recurrent left ventricular outflow tract obstruction compared with the published data.

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  • (PMID = 16580434.001).
  • [ISSN] 1097-685X
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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96. Patiroglu T, Unal E, Yikilmaz A, Koker MY, Ozturk MK: Atypical presentation of chronic granulomatous disease in an adolescent boy with frontal lobe located Aspergillus abscess mimicking intracranial tumor. Childs Nerv Syst; 2010 Feb;26(2):149-54
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  • BACKGROUND: Chronic granulomatous disease (CGD) is an uncommon congenital phagocyte disorder characterized by recurrent life-threatening infections.
  • CGD generally present with recurrent suppurative infections, however, intracranial fungal abscess complicating CGD may cause a diagnostic problem to anyone unfamiliar with its clinical and radiological features.

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  • [CommentIn] Childs Nerv Syst. 2010 Jun;26(6):733-4; author reply 735 [20396894.001]
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  • (PMID = 19859718.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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97. Pang D: Atlantoaxial rotatory fixation. Neurosurgery; 2010 Mar;66(3 Suppl):161-83
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  • The AARF patients are further classified as acute if treatment is started less than 1 month from the onset of symptoms, as subacute if the delay in treatment is 1 to 3 months, and chronic if treatment delay exceeds 3 months.
  • Recurrent slippage and irreducibility are treated with C1-C2 fusion.
  • The difficulty and duration of treatment, the number of recurrent slippage, the rate of irreducibility, the need for halo and fusion, and the percentage ultimately losing normal C1-C2 rotation are significantly greater in type I patients than type III patients, with type II patients somewhere in between.
  • Likewise, all parameters are much worse in patients with any type of chronic AARF than acute AARF.
  • The worse subgroup is chronic type I versus the best subgroup of acute type III.
  • Recurrent AARF patients do much worse than nonrecurrent AARF patients.
  • Recurrent dislocation and incomplete reduction should be treated with posterior C1-C2 fusion in the best achievable alignment.

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  • (PMID = 20173520.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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98. Su WJ, Chen HL, Lai HS, Ni YH, Chang MH: Pancreaticobiliary anomalies is the leading cause of childhood recurrent pancreatitis. J Formos Med Assoc; 2007 Feb;106(2):119-25
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  • [Title] Pancreaticobiliary anomalies is the leading cause of childhood recurrent pancreatitis.
  • BACKGROUND/PURPOSE: To explore the etiology, age and gender distribution, complications, and prognosis of recurrent pediatric pancreatitis.
  • Only 25 diagnosed with recurrent pancreatitis, based on two or more episodes of pancreatitis, elevated serum amylase and/or lipase levels > or = 3 times the upper limit of normal, radiographic evidence, and clinical symptoms, were enrolled.
  • The recurrence rate of pediatric pancreatitis was 27.2%.
  • Recurrent pancreatitis was associated with pancreaticobiliary structural anomalies (n = 7), biliary stones or sludge (n = 4), hyperlipidemia (n = 3), pseudopapillary tumor of the pancreas (n = 2), trauma (n = 2), hypoxic encephalopathy with recurrent bacteremia and sepsis (n = 1), and idiopathic (n = 6).
  • No patient died of recurrent pancreatitis.
  • Long-term morbidity after recurrent pancreatitis presented as gout, diabetes mellitus, non-alcoholic steatohepatitis, and chronic pancreatitis.
  • CONCLUSION: For children who suffer from recurrent pancreatitis, pancreaticobiliary structural anomalies should be considered first.

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  • (PMID = 17339155.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
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99. Sharma S, K Gupta D: Male genitoplasty for intersex disorders. Adv Urol; 2008;:685897
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Case records of intersex patients undergoing male genitoplasty from Pediatric Intersex clinic were studied.
  • Complications included fistula (45), recurrent fistula (11), stricture (12), baggy urethra (8) and recurrent infection due to persistent vaginal pouch (5).

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  • (PMID = 19009033.001).
  • [ISSN] 1687-6369
  • [Journal-full-title] Advances in urology
  • [ISO-abbreviation] Adv Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2581734
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100. Molina-Teran A, Hilliard TN, Saglani S, Haxby E, Scallan M, Bush A, Davies JC: Safety of endobronchial biopsy in children with cystic fibrosis. Pediatr Pulmonol; 2006 Nov;41(11):1021-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of this retrospective study was to compare the safety of EBB in children with CF and those with other conditions, the most frequent of which included primary ciliary dyskinesia and recurrent lower respiratory tract infections.






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