[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 553
1. Cipollo JF, Awad AM, Costello CE, Hirschberg CB: N-Glycans of Caenorhabditis elegans are specific to developmental stages. J Biol Chem; 2005 Jul 15;280(28):26063-72
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The N-glycan profile of each developmental stage (Larva 1, Larva 2, Larva 3, Larva 4, and Dauer and adult) appears to be unique.
  • The pattern of complex N-glycans was stage-specific with the general trend of number and abundance of glycans being Dauer approximately = L1 > adult approximately = L4 > L3 approximately = L2.

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. HYDROGEN .
  • Hazardous Substances Data Bank. 2-AMINOBENZAMIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15899899.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / F32 GM66486; United States / NCRR NIH HHS / RR / P41-RR10888; United States / NIGMS NIH HHS / GM / R01-GM30365; United States / NCRR NIH HHS / RR / S10-RR15942
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Oligosaccharides; 0 / Polysaccharides; 0 / ortho-Aminobenzoates; 107-73-3 / Phosphorylcholine; 7YNJ3PO35Z / Hydrogen; 88-68-6 / anthranilamide; 9007-34-5 / Collagen
  •  go-up   go-down


2. Lemire B: Mitochondrial genetics. WormBook; 2005;:1-10
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The mitochondrial genome content of the developing nematode is developmentally regulated; it increases about 30-fold between the L1 and the adult stages and blocking the increase leads to larval arrest.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18023115.001).
  • [ISSN] 1551-8507
  • [Journal-full-title] WormBook : the online review of C. elegans biology
  • [ISO-abbreviation] WormBook
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Helminth; 0 / DNA, Mitochondrial
  • [Number-of-references] 46
  • [Other-IDs] NLM/ PMC4781428
  •  go-up   go-down


3. Zhang Y, Bo X, Schoepfer R, Holtmaat AJ, Verhaagen J, Emson PC, Lieberman AR, Anderson PN: Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo. Proc Natl Acad Sci U S A; 2005 Oct 11;102(41):14883-8
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo.
  • Neuronal expression of growth-associated protein 43 (GAP-43) and the cell adhesion molecule L1 has been correlated with CNS axonal growth and regeneration, but it is not known whether expression of these molecules is necessary for axonal regeneration to occur.
  • We have taken advantage of the fact that Purkinje cells do not express GAP-43 or L1 in adult mammals or regenerate axons into peripheral nerve grafts to test the importance of these molecules for axonal regeneration in vivo.
  • Transgenic mice were generated in which Purkinje cells constitutively express L1 or both L1 and GAP-43 under the Purkinje cell-specific L7 promoter, and regeneration of Purkinje cell axons into peripheral nerve grafts implanted into the cerebellum was examined.
  • Purkinje cells expressing GAP-43 or L1 showed minor enhancement of axonal sprouting.
  • Purkinje cells expressing both GAP-43 and L1 showed more extensive axonal sprouting and axonal growth into the proximal portion of the graft.
  • The results demonstrate that GAP-43 and L1 coexpressed in Purkinje cells can act synergistically to switch these regeneration-incompetent CNS neurons into a regeneration-competent phenotype and show that coexpression of these molecules is a key regulator of the regenerative ability of intrinsic CNS neurons in vivo.


Advertisement
4. Kaifi JT, Strelow A, Schurr PG, Reichelt U, Yekebas EF, Wachowiak R, Quaas A, Strate T, Schaefer H, Sauter G, Schachner M, Izbicki JR: L1 (CD171) is highly expressed in gastrointestinal stromal tumors. Mod Pathol; 2006 Mar;19(3):399-406
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] L1 (CD171) is highly expressed in gastrointestinal stromal tumors.
  • L1 cell adhesion molecule (CD171) plays an essential role in tumor progression.
  • The aim of this study was to determine expression of L1 in GISTs, smooth muscle tumors, desmoid-type fibromatosis and peripheral nerve sheath tumors (PNSTs).
  • We retrospectively analyzed a total of 129 surgically resected primary tumors or metastases of 72 GISTs, 29 smooth muscle tumors, seven PNSTs and 21 desmoid-type fibromatosis by immunohistochemistry for c-kit, CD34, smooth muscle actin, desmin, vimentin, S-100 and L1 expression.
  • L1 expression was detected in 53 (74%) of 72 GISTs but in none of 29 smooth muscle tumors or 21 desmoid-type fibromatosis (P<0.01 by Fisher's test).
  • In all, four (57%) of seven peripheral nerve sheath tumors were L1-positive.
  • Survival analysis of 55 surgically completely resected GISTs presenting without metastasis at initial diagnosis revealed no tumor-specific death among L1-negative patients (P=0.13 by log-rank test; median follow-up time 41 months) and one recurrence was observed (P=0.12).
  • Interestingly high levels of L1 were seen in tumor vascular endothelial cells of smooth muscle tumors and PNSTs, but not in GISTs.
  • Our data show that L1 is highly expressed in GISTs but not in smooth muscle tumors and desmoid-type fibromatosis being important differential diagnoses.
  • The trend towards a reduced survival of L1-positive patients in this study has to be further evaluated in future trials with higher patient numbers.
  • [MeSH-major] Gastrointestinal Stromal Tumors / pathology. Neural Cell Adhesion Molecule L1 / biosynthesis
  • [MeSH-minor] Adult. Diagnosis, Differential. Fibromatosis, Aggressive / metabolism. Fibromatosis, Aggressive / pathology. Humans. Immunohistochemistry. Leiomyoma / metabolism. Leiomyoma / pathology. Middle Aged. Nerve Sheath Neoplasms / metabolism. Nerve Sheath Neoplasms / pathology. Survival Analysis

  • Genetic Alliance. consumer health - Gastrointestinal Stromal Tumors.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16400320.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecule L1
  •  go-up   go-down


5. Wachowiak R, Fiegel HC, Kaifi JT, Quaas A, Krickhahn A, Schurr PG, Erttmann R, Schachner M, Kluth D, Sauter G, Izbicki JR: L1 is associated with favorable outcome in neuroblastomas in contrast to adult tumors. Ann Surg Oncol; 2007 Dec;14(12):3575-80
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] L1 is associated with favorable outcome in neuroblastomas in contrast to adult tumors.
  • L1, a neuronal cell adhesion molecule, is associated with poor survival in malignant adult tumors.
  • The aim of the current study was to determine expression of L1 in pediatric neuroblastoma.
  • METHODS: L1 expression was assessed on a tissue microarray with 66 surgically resected neuroblastoma samples by immunohistochemistry with a monoclonal antibody and peroxidase method.
  • Additionally, mRNA expression was analyzed by reverse transcriptase-polymerase chain reaction with L1-specific primers.
  • RESULTS: L1 was detected in 57 (86%) of 66 neuroblastomas, whereas 9 (14%) were L1 negative.
  • Analysis with Kaplan-Meier method revealed a surprising and contrary finding to adult tumor entities: an association of L1 positivity with better event-free and overall survival (P < .001 and P < .01 by log rank test).
  • Multivariate Cox regression analysis showed an independent prognostic impact of L1 negativity for event-free and overall survival of the children (P < .05).
  • CONCLUSIONS: In contrast to adult tumor entities, where L1 is associated with aggressive clinical behavior, our data show that L1 predicts good outcome in children with neuroblastoma.
  • This novel finding suggests an inverse role of L1 in neuroblastoma.
  • Future studies might focus on the molecular basis of the varying effect of L1 in different tumors.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Gene Expression Regulation, Neoplastic. Neural Cell Adhesion Molecule L1 / metabolism. Neuroblastoma / metabolism
  • [MeSH-minor] Adult. Child, Preschool. Humans. Immunoenzyme Techniques. Infant. Neoplasm Staging. Prognosis. RNA, Messenger / genetics. RNA, Messenger / metabolism. Retrospective Studies. Reverse Transcriptase Polymerase Chain Reaction. Survival Rate. Tissue Array Analysis

  • MedlinePlus Health Information. consumer health - Neuroblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17917782.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neural Cell Adhesion Molecule L1; 0 / RNA, Messenger
  •  go-up   go-down


6. Zeng L, Yu SY, Hu ZH, Zhang J: [Polymorphisms of human papillomavirus type 81 L1 gene in patients with cervical lesions in Guangdong]. Nan Fang Yi Ke Da Xue Xue Bao; 2008 Dec;28(12):2210-2
MedlinePlus Health Information. consumer health - Cervical Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Polymorphisms of human papillomavirus type 81 L1 gene in patients with cervical lesions in Guangdong].
  • OBJECTIVE: To investigate the positivity rates and genetic polymorphism of human papillomavirus (HPV) type 81 (HPV81) L1 gene in patients with cervical cancer in Guangdong.
  • METHODS: HPV L1 genes fragment in 1200 positive cervical samples detected with HC-II for high-risk HPV DNA were amplified by HPV-specific PCR with consensus primers, and the L1 genes of HPV81 were sequenced for mutation analysis.
  • Point mutations of HPV81 L1 gene were found in all of the samples.
  • CONCLUSION: Compared with the HPV81 prototypes published in GenBank, several new point mutations are found in the L1 genes of the HPV81 in Guangdong, and these mutations are close to those found in Japan.
  • [MeSH-minor] Adult. China. Female. Humans. Point Mutation

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19114360.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Capsid Proteins; 0 / HPV L1 protein, Human papillomavirus; 0 / Oncogene Proteins, Viral
  •  go-up   go-down


7. De Oliveira Vasconcelos V, De Almeida Vitor RW, Dos Santos Lima W: Identification of stage-specific proteins of Angiostrongylus vasorum (Baillet, 1866) Kamensky. Parasitol Res; 2008 Feb;102(3):389-95
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sera of ten dogs infected with Angiostrongylus vasorum were analyzed by immunoblotting proteins of first stage larvae (L1) and adult parasites.
  • The molecular weights (m.w.) of the principal L1 proteins identified by IgG, IgM, IgA, and IgE were 18-118 kDa and those of the adult parasite were 28-209 kDa.
  • The L1 proteins had not been recognized by IgG, IgM, and IgA antibodies in sera of dogs naturally infected with Toxocara canis, Ancylostoma caninum, and Dipylidium caninum, although only weakly by IgE.
  • Adult parasite proteins were recognized by antibodies in sera of dogs naturally infected with gastrointestinal helminths.
  • Adult parasite proteins with m.w. of approximately 51, 63, 92, and 209 kDa recognized by IgG could be used for specific diagnosis of canine angiostrongylosis.

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Vet Parasitol. 2002 May 30;106(1):83-7 [11992714.001]
  • [Cites] Vet Rec. 1973 Feb 24;92 (8):195-7 [4705867.001]
  • [Cites] C R Acad Sci Hebd Seances Acad Sci D. 1970 Sep 14;271(11):936-9 [4990602.001]
  • [Cites] Trop Med Int Health. 1997 Mar;2(3):254-60 [9491104.001]
  • [Cites] Southeast Asian J Trop Med Public Health. 2001 Jun;32(2):308-13 [11556581.001]
  • [Cites] Vet Rec. 1994 Nov 5;135(19):447-52 [7863592.001]
  • [Cites] Bull Epizoot Dis Afr. 1974 Mar;22(1):55-68 [4471463.001]
  • [Cites] Southeast Asian J Trop Med Public Health. 1996 Jun;27(2):291-6 [9279992.001]
  • [Cites] J Biol Chem. 1951 Nov;193(1):265-75 [14907713.001]
  • [Cites] Parasitol Res. 1999 Mar;85(3):200-5 [9951963.001]
  • [Cites] Z Parasitenkd. 1985;71(6):789-800 [2417425.001]
  • (PMID = 18060430.001).
  • [ISSN] 0932-0113
  • [Journal-full-title] Parasitology research
  • [ISO-abbreviation] Parasitol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Helminth; 0 / Antigens, Helminth; 0 / Helminth Proteins
  •  go-up   go-down


8. Mwangangi JM, Muturi EJ, Shililu J, Muriu SM, Jacob B, Kabiru EW, Mbogo CM, Githure J, Novak R: Survival of immature Anopheles arabiensis (Diptera: Culicidae) in aquatic habitats in Mwea rice irrigation scheme, central Kenya. Malar J; 2006 Nov 24;5:114
Hazardous Substances Data Bank. Water .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Pre-adult developmental time for An. arabiensis in the trays in the experimental set up in the screen house was 11.85 days from eclosion to emergence.
  • A total of 590 individuals emerged into adults, giving an overall survivorship from L1 to adult emergence of 69.4%.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Med Vet Entomol. 2003 Mar;17(1):61-6 [12680927.001]
  • [Cites] J Vector Ecol. 2002 Jun;27(1):8-20 [12125876.001]
  • [Cites] J Med Entomol. 1979 Oct 12;16(3):207-18 [537004.001]
  • [Cites] Med Vet Entomol. 2000 Dec;14(4):361-8 [11129699.001]
  • [Cites] Am J Trop Med Hyg. 2003 Jun;68(6):734-42 [12887036.001]
  • [Cites] J Med Entomol. 1977 Jan 31;13(4-5):535-45 [845895.001]
  • [Cites] J Med Entomol. 2004 May;41(3):333-9 [15185933.001]
  • [Cites] Bull World Health Organ. 1971;45(2):169-80 [5316615.001]
  • [Cites] Am J Trop Med Hyg. 1993 Oct;49(4):520-9 [8214283.001]
  • [Cites] J Med Entomol. 1982 Jul 28;19(4):413-22 [7154019.001]
  • [Cites] Acta Trop. 2004 Jan;89(2):187-92 [14732240.001]
  • [Cites] J Vector Ecol. 2006 Dec;31(2):245-51 [17249341.001]
  • (PMID = 17125501.001).
  • [ISSN] 1475-2875
  • [Journal-full-title] Malaria journal
  • [ISO-abbreviation] Malar. J.
  • [Language] ENG
  • [Grant] United States / PHS HHS / / U01-A154889
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 059QF0KO0R / Water
  • [Other-IDs] NLM/ PMC1698490
  •  go-up   go-down


9. Jakeman LB, Chen Y, Lucin KM, McTigue DM: Mice lacking L1 cell adhesion molecule have deficits in locomotion and exhibit enhanced corticospinal tract sprouting following mild contusion injury to the spinal cord. Eur J Neurosci; 2006 Apr;23(8):1997-2011
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mice lacking L1 cell adhesion molecule have deficits in locomotion and exhibit enhanced corticospinal tract sprouting following mild contusion injury to the spinal cord.
  • L1 is a member of the immunoglobulin superfamily of cell adhesion molecules that is associated with axonal growth, including formation of the corticospinal tract (CST).
  • The present study describes the effects of L1 deletion on hindlimb function in locomotion, and examines the role of L1 in recovery and remodeling after contusive spinal cord injury (SCI) in mice.
  • Uninjured adult L1 knockout (Y/-) mice had impaired performance on locomotor tests compared with their wild-type littermates (Y/+).
  • Thus, L1 is important for the development of multiple spinal projections and also contributes to the restriction of CST sprouting rostral to the site of a SCI in adults.

  • MedlinePlus Health Information. consumer health - Spinal Cord Injuries.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. BIOTIN .
  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16630048.001).
  • [ISSN] 0953-816X
  • [Journal-full-title] The European journal of neuroscience
  • [ISO-abbreviation] Eur. J. Neurosci.
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / R01 NS-043246; United States / NINDS NIH HHS / NS / P30 NS-045758; United States / NINDS NIH HHS / NS / NS043246-02; United States / NINDS NIH HHS / NS / R01 NS043246-02; United States / NINDS NIH HHS / NS / R01 NS043246
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  • [Chemical-registry-number] 0 / 2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; 0 / Neural Cell Adhesion Molecule L1; 0 / Stilbamidines; 0 / biotinylated dextran amine; 6SO6U10H04 / Biotin; K3R6ZDH4DU / Dextrans
  •  go-up   go-down


10. Zaretsky E, Bar-Shalom EG: Does reading in shallow L1 orthography slow attrition of language-specific morphological structures? Clin Linguist Phon; 2010 Jan;24(4-5):401-15
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does reading in shallow L1 orthography slow attrition of language-specific morphological structures?
  • This study looks at the relationship between L1 (Russian) attrition and L1 reading ability in Russian-English-speaking bilingual children.
  • Nine out of 10 children participants were born in the US and used L1 as their primary language of interaction within the family, but the intensity and the length of uninterrupted L1 exposure differed for each child.
  • All participants were tested on perception (grammaticality judgement) and production (narrative) tasks to assess their sensitivity to and retention of the morphosyntactic structure of L1.
  • All children showed some attrition of grammatical morphemes, specifically in the Russian systems of declension and conjugation; however, the degree of attrition correlated with reading ability in L1, i.e. children with L1 reading skills showed a lesser degree of attrition for some language-specific morphosyntactic structures.
  • This finding shows interdependence of oral and reading skills and points to the role reading in language with shallow orthography may play in preservation of L1 grammatical structures in oral language.
  • [MeSH-minor] Adolescent. Adult. Aging. Analysis of Variance. Child. Child, Preschool. Female. Humans. Language Tests. Learning. Male. Middle Aged. Time Factors. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20345267.001).
  • [ISSN] 1464-5076
  • [Journal-full-title] Clinical linguistics & phonetics
  • [ISO-abbreviation] Clin Linguist Phon
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


11. Kim YJ, Bridwell KH, Lenke LG, Rhim S, Kim YW: Is the T9, T11, or L1 the more reliable proximal level after adult lumbar or lumbosacral instrumented fusion to L5 or S1? Spine (Phila Pa 1976); 2007 Nov 15;32(24):2653-61
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is the T9, T11, or L1 the more reliable proximal level after adult lumbar or lumbosacral instrumented fusion to L5 or S1?
  • OBJECTIVE: To compare the postoperative proximal junctional change and revision prevalence as influenced by 3 different proximal levels after adult lumbar deformity instrumented fusion from the distal thoracic/upper lumbar spine (T9-L2) to L5 or S1.
  • SUMMARY OF BACKGROUND DATA: Few comparative studies on postoperative sagittal plane change and revision prevalence as influenced by 3 different proximal levels after adult lumbar deformity instrumented fusion from the distal thoracic/upper lumbar spine (T9-L2) to L5 or S1 have been published.
  • Many surgeons have hypothesized that stopping proximally in the upper lumbar spine (L1 or L2) or the thoracolumbar junction (T11 or T12) would lead to a high percentage of rapid proximal degeneration, kyphosis, and decompensation because of the concentration of stress on these relatively mobile segments.
  • METHODS: A clinical and radiographic assessment in addition to revision prevalence of 125 adult lumbar deformity patients (average age 57.1 year) who underwent long (average 7.1 vertebrae) segmental posterior spinal instrumented fusion from the distal thoracic/upper lumbar spine (T9-L2) to L5 or S1 with a minimum 2-year follow-up (2-19.8 year follow-up) were compared as influenced by T9-T10 (group 1, n = 37), T11-T12 (group 2, n = 49), and L1-L2 (group 3, n = 39) proximal fusion levels.
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Lumbar Vertebrae / radiography. Lumbar Vertebrae / surgery. Male. Middle Aged. Prevalence. Reoperation / statistics & numerical data. Retrospective Studies. Sacrum / radiography. Sacrum / surgery. Thoracic Vertebrae / radiography. Thoracic Vertebrae / surgery. Treatment Outcome

  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - Scoliosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18007240.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


12. Elston-Güttler KE, Paulmann S, Kotz SA: Who's in control? Proficiency and L1 influence on L2 processing. J Cogn Neurosci; 2005 Oct;17(10):1593-610

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Who's in control? Proficiency and L1 influence on L2 processing.
  • We report three reaction time (RT)/event-related brain potential (ERP) semantic priming lexical decision experiments that explore the following in relation to L1 activation during L2 processing:.
  • (1) the role of L2 proficiency, (2) the role of sentence context, and (3) the locus of L1 activations (orthographic vs. semantic).
  • All experiments used German (L1) homonyms translated into English (L2) to form prime-target pairs (pine-jaw for Kiefer) to test whether the L1 caused interference in an all-L2 experiment.
  • Based on these results, we argue that cognitive control relating to translational activation is modulated by (1) L2 proficiency, as the early interference in the N200 was observed only for low-proficiency learners, and (2) sentence context, as it helps high-proficiency learners control L1 activation.
  • As reversed priming was observed in the N200 and not the N400 component, we argue that (3) the locus of the L1 activations was orthographic.
  • [MeSH-minor] Adult. Brain Mapping. Electroencephalography / methods. Female. Humans. Language Tests / statistics & numerical data. Male. Photic Stimulation / methods. Time Factors

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16269099.001).
  • [ISSN] 0898-929X
  • [Journal-full-title] Journal of cognitive neuroscience
  • [ISO-abbreviation] J Cogn Neurosci
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


13. Intapan PM, Tantrawatpan C, Maleewong W, Wongkham S, Wongkham C, Nakashima K: Potent epitopes derived from Fasciola gigantica cathepsin L1 in peptide-based immunoassay for the serodiagnosis of human fascioliasis. Diagn Microbiol Infect Dis; 2005 Oct;53(2):125-9
Immune Epitope Database and Analysis Resource. gene/protein/disease-specific - Related Immune Epitope Information .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Potent epitopes derived from Fasciola gigantica cathepsin L1 in peptide-based immunoassay for the serodiagnosis of human fascioliasis.
  • A peptide-based enzyme-linked immunosorbent assay (ELISA) was developed and evaluated for its diagnostic ability to detect human IgG antibodies against Fasciola gigantica cathepsin L1.
  • Two previously identified B-cell epitopes of cathepsin L1 were synthesized as single synthetic peptides (acetyl-DKIDWRESGYVTEVKDQGNC-carboxamide and acetyl-DKIDWRESGYVTELKDQGNC-carboxamide) and their diagnostic potential was evaluated.
  • The peptide-based ELISA was compared with an indirect ELISA with crude excretory-secretory products or with partially purified specific 27-kDa (FG27) antigen from adult F. gigantica.

  • Genetic Alliance. consumer health - Fascioliasis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16168617.001).
  • [ISSN] 0732-8893
  • [Journal-full-title] Diagnostic microbiology and infectious disease
  • [ISO-abbreviation] Diagn. Microbiol. Infect. Dis.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ AF112566/ AF239264/ AF239267
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Helminth; 0 / Epitopes; EC 3.4.- / Cathepsins; EC 3.4.22.- / Cysteine Endopeptidases; EC 3.4.22.15 / CTSL1 protein, human; EC 3.4.22.15 / Cathepsin L
  •  go-up   go-down


14. Negri G, Bellisano G, Zannoni GF, Rivasi F, Kasal A, Vittadello F, Antoniazzi S, Faa G, Ambu R, Egarter-Vigl E: p16 ink4a and HPV L1 immunohistochemistry is helpful for estimating the behavior of low-grade dysplastic lesions of the cervix uteri. Am J Surg Pathol; 2008 Nov;32(11):1715-20
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p16 ink4a and HPV L1 immunohistochemistry is helpful for estimating the behavior of low-grade dysplastic lesions of the cervix uteri.
  • The aim of the study was to evaluate p16 ink4a and L1 as immunohistochemical markers of the biologic potentiality of low-grade dysplasia of the uterine cervix.
  • In group A, all CIN3 were p16 ink4a positive (p16+) and L1 negative (L1-).
  • The CIN1 of this group were p16+L1- and p16+L1+ in 68.42% and 31.57%, respectively.
  • In group B, the p16+L1-, p16+L1+, p16-L1+, and p16-L1- patterns were found in 3.57%, 25%, 14.29%, and 57.14%, respectively.
  • Overall, 96.29% p16+L1- CIN1 were found in group A, whereas all the p16-L1+ and p16-L1- CIN1 were found in group B.
  • The results of the study show that p16 ink4a and L1 immunohistochemistry can be helpful for estimating the biologic potentiality of low-grade squamous cervical lesions.
  • Particularly in cases in which the grade of the lesion is morphologically difficult to assess, the p16/L1 expression pattern could be useful for planning the clinical management of these women.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / virology. Disease Progression. Female. Humans. Immunohistochemistry. Papillomavirus Infections / complications. Papillomavirus Infections / metabolism. Papillomavirus Infections / pathology. Prognosis

  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18769337.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Capsid Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / HPV L1 protein, Human papillomavirus; 0 / Oncogene Proteins, Viral
  •  go-up   go-down


15. Ben QW, Wang JC, Liu J, Zhu Y, Yuan F, Yao WY, Yuan YZ: Positive expression of L1-CAM is associated with perineural invasion and poor outcome in pancreatic ductal adenocarcinoma. Ann Surg Oncol; 2010 Aug;17(8):2213-21
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Positive expression of L1-CAM is associated with perineural invasion and poor outcome in pancreatic ductal adenocarcinoma.
  • We evaluated whether L1 cell adhesion molecule (L1-CAM) and glial cell line-derived neurotrophic factor (GDNF) expression in PDAC correlated with neural invasion and overall survival on a large cohort of previously untreated patients.
  • METHODS: L1-CAM and GDNF were examined by immunohistochemistry in pancreatic cancer tissue samples of 94 cases with PDAC on a tissue microarray.
  • RESULTS: L1-CAM and GDNF were overexpressed in pancreatic cancer tissues compared with the adjacent normal tissues of pancreas.
  • Positive L1-CAM expression was associated with node involvement (P = 0.007), vascular invasion (P = 0.012), perineural invasion (P = 0.001), and higher degree of pain (P = 0.005).
  • In univariate analysis, tissue expression of L1-CAM was associated with poor survival (hazard ratio, 2.508; 95% confidence interval, 1.551-4.053; P < 0.001), and this was also significant in multivariate analysis (hazard ratio, 2.046; 95% confidence interval, 1.200-3.488; P = 0.009).
  • CONCLUSIONS: Enhanced expression of L1-CAM may contribute to the pain syndrome and perineural invasion and may correlate with poor overall survival in human pancreatic cancer.
  • [MeSH-major] Carcinoma, Pancreatic Ductal. Neoplasm Proteins / metabolism. Neural Cell Adhesion Molecule L1 / metabolism. Pancreatic Neoplasms. Peripheral Nerves / pathology
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Female. Follow-Up Studies. Glial Cell Line-Derived Neurotrophic Factor / metabolism. Humans. Male. Middle Aged. Neoplasm Invasiveness. Pain Measurement. Prognosis. Survival Rate

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20162456.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Cell Line-Derived Neurotrophic Factor; 0 / Neoplasm Proteins; 0 / Neural Cell Adhesion Molecule L1
  •  go-up   go-down


16. Brand AM, Varghese G, Majewski W, Hawdon JM: Identification of a DAF-7 ortholog from the hookworm Ancylostoma caninum. Int J Parasitol; 2005 Dec;35(14):1489-98
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ac-daf-7 mRNA was strongly detected by reverse transcriptase PCR in L3 and serum stimulated L3 cDNA, and weakly in cDNA from L1 and adult life cycle stages.
  • Antiserum against Escherichia coli expressed recombinant Ac-DAF-7 detected the mature protein in L3 and adult soluble extracts, but not in excretory/secretory products from serum stimulated L3 or adults.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16135366.001).
  • [ISSN] 0020-7519
  • [Journal-full-title] International journal for parasitology
  • [ISO-abbreviation] Int. J. Parasitol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ DQ058687/ DQ059758
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Helminth; 0 / Caenorhabditis elegans Proteins; 0 / DAF-7 protein, C elegans; 0 / Transforming Growth Factor beta
  •  go-up   go-down


17. Kaifi JT, Zinnkann U, Yekebas EF, Schurr PG, Reichelt U, Wachowiak R, Fiegel HC, Petri S, Schachner M, Izbicki JR: L1 is a potential marker for poorly-differentiated pancreatic neuroendocrine carcinoma. World J Gastroenterol; 2006 Jan 7;12(1):94-8
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] L1 is a potential marker for poorly-differentiated pancreatic neuroendocrine carcinoma.
  • AIM: To determine the expression of L1 in pancreatic neuroendocrine tumor and to correlate it with WHO classification of this tumor.
  • METHODS: We retrospectively analyzed L1 expression in 63 cases of pancreatic neuroendocrine tumor by immunohistochemistry on paraffin sections of primary tumors or metastases.
  • Staining was performed by peroxidase technique with monoclonal antibody UJ127.11 against human L1.
  • RESULTS: L1 was detected in 5 (7.9%) of 63 pancreatic neuroendocrine tumors.
  • Four (44.4%) of 9 poorly-differentiated carcinomas expressed L1.
  • In contrast, only 1 (1.9%) of 54 well-differentiated tumors or carcinomas was positive for L1.
  • Cross table analysis showed a significant association between L1 expression and classification of neuroendocrine tumors of the pancreas (P<0.01).
  • CONCLUSION: L1 is specifically expressed in poorly-differentiated pancreatic neuroendocrine carcinomas that are known to have the worst prognosis.
  • L1 might be a marker for risk prediction of patients diagnosed with pancreatic neuroendocrine carcinomas.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neural Cell Adhesion Molecule L1 / analysis. Neuroendocrine Tumors / chemistry. Pancreatic Neoplasms / chemistry
  • [MeSH-minor] Adult. Aged. Female. Humans. Immunohistochemistry. Male. Middle Aged

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Histopathology. 2000 May;36(5):421-32 [10792483.001]
  • [Cites] Carcinogenesis. 2005 Jan;26(1):17-25 [15447976.001]
  • [Cites] Digestion. 2000;62 Suppl 1:19-26 [10940683.001]
  • [Cites] J Surg Oncol. 2001 May;77(1):49-54 [11344483.001]
  • [Cites] J Cell Biol. 2001 Nov 12;155(4):661-73 [11706054.001]
  • [Cites] Semin Cancer Biol. 2002 Apr;12(2):89-96 [12027580.001]
  • [Cites] Eur J Cancer. 2002 Sep;38(13):1708-16 [12175686.001]
  • [Cites] Cancer Lett. 2003 Jan 28;189(2):237-47 [12490317.001]
  • [Cites] J Biol Chem. 2003 Mar 21;278(12):10381-8 [12529374.001]
  • [Cites] J Cutan Pathol. 2003 Jul;30(6):363-8 [12834484.001]
  • [Cites] J Cell Biol. 2003 Aug 18;162(4):719-30 [12925712.001]
  • [Cites] Lancet. 2003 Sep 13;362(9387):869-75 [13678974.001]
  • [Cites] Ann N Y Acad Sci. 2004 Apr;1014:13-27 [15153416.001]
  • [Cites] Expert Rev Mol Diagn. 2004 Jul;4(4):455-62 [15225093.001]
  • [Cites] Brain Pathol. 2004 Jul;14(3):297-303 [15446585.001]
  • [Cites] Neuroendocrinology. 2004;80 Suppl 1:12-5 [15477709.001]
  • [Cites] Int J Cancer. 1989 Apr 15;43(4):709-12 [2703275.001]
  • [Cites] Hybridoma. 1991 Aug;10(4):481-91 [1937498.001]
  • [Cites] J Natl Cancer Inst. 1994 Jun 1;86(11):829-35 [8182763.001]
  • [Cites] J Cell Biol. 1996 Feb;132(3):475-85 [8636223.001]
  • [Cites] Curr Opin Cell Biol. 1997 Oct;9(5):627-34 [9330865.001]
  • [Cites] Cancer Res. 1998 Jul 15;58(14):2935-40 [9679949.001]
  • [Cites] J Biol Chem. 1999 Aug 27;274(35):24602-10 [10455125.001]
  • [Cites] EMBO J. 1999 Sep 1;18(17):4744-53 [10469653.001]
  • [Cites] J Biol Chem. 2000 May 19;275(20):15490-7 [10809781.001]
  • (PMID = 16440424.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neural Cell Adhesion Molecule L1
  • [Other-IDs] NLM/ PMC4077503
  •  go-up   go-down


18. Yoshida T, Sano T, Kanuma T, Owada N, Sakurai S, Fukuda T, Nakajima T: Immunochemical analysis of HPV L1 capsid protein and p16 protein in liquid-based cytology samples from uterine cervical lesions. Cancer; 2008 Apr 25;114(2):83-8
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunochemical analysis of HPV L1 capsid protein and p16 protein in liquid-based cytology samples from uterine cervical lesions.
  • BACKGROUND: HPV L1 capsid protein is expressed together with the production of infectious viral particles, but its expression and relation to p16 expression, which has been a surrogate marker for human papilloma virus (HPV) infection in cervix, are little studied in cytology samples.
  • The authors aimed to elucidate the relation between L1 capsid protein and p16 protein expressions in liquid-based samples from uterine cervical lesions.
  • METHODS: Immunochemical analyses using antibodies against L1 capsid protein and p16 protein were carried out on cytological materials obtained from uterine cervical lesions of low-grade squamous intraepithelial lesions (LSILs), high-grade squamous intraepithelial lesions (HSILs), and squamous cell carcinomas (SCCs).
  • RESULTS: L1 capsid protein was positive in 30% of LSILs and 12% of HSILs, but in 0% of SCCs.
  • L1-positive cells were only observed in the superficial layer, whereas p16-positive cells were seen throughout the full thickness of the epithelium.
  • The relation between L1 capsid protein and p16 protein, p16(-)/L1(+) cases represented 44% of LSILs, but 0% of HSILs, and 0% of SCCs, whereas p16(+)/L1(-) cases represented 82% of LSILs, 88% of HSILs, and 100% of SCCs.
  • CONCLUSIONS: Expression of L1 capsid protein decreased with lesion progression from LSILs to HSILs and SCCs, whereas p16 protein was positive in all HSILs and SCCs.
  • The correlation between L1 and p16 expressions suggests that L1(-)/p16(+) cases have the potential for progression, whereas L1(+)/p16(-) and L1(-)/p16(-) cases may be nonprogressive lesions or potentially in remission.
  • [MeSH-minor] Adult. Aged. Female. Humans. Middle Aged. Prognosis. Remission Induction

  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) American Cancer Society.
  • (PMID = 18300235.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Capsid Proteins; 0 / HPV L1 protein, Human papillomavirus; 0 / Neoplasm Proteins; 0 / Oncogene Proteins, Viral; 0 / P16 protein, human
  •  go-up   go-down


19. Bertolin C, Boaretto F, Barbon G, Salviati L, Lapi E, Divizia MT, Garavelli L, Occhi G, Vazza G, Mostacciuolo ML: Novel mutations in the L1CAM gene support the complexity of L1 syndrome. J Neurol Sci; 2010 Jul 15;294(1-2):124-6
SciCrunch. KEGG: Data: Disease Annotation .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Novel mutations in the L1CAM gene support the complexity of L1 syndrome.
  • X-linked hydrocephalus, MASA syndrome, X-linked complicated Spastic Paraplegia Type I and X-linked partial agenesis of the corpus callosum are the four rare diseases usually referred to L1 syndrome, caused by mutations in the L1CAM gene.
  • Patients' phenotype evaluation revealed a correlation between the number of clinical features typical of L1 syndrome and the chance to find causative mutation.
  • [MeSH-major] Agenesis of Corpus Callosum. Genetic Diseases, X-Linked / genetics. Hydrocephalus / genetics. Mutation. Neural Cell Adhesion Molecule L1 / genetics. Spastic Paraplegia, Hereditary / genetics
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Infant. Male. Mental Retardation, X-Linked / genetics. Middle Aged. Phenotype. Syndrome. Thumb / abnormalities. Young Adult

  • MedlinePlus Health Information. consumer health - Hydrocephalus.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20447653.001).
  • [ISSN] 1878-5883
  • [Journal-full-title] Journal of the neurological sciences
  • [ISO-abbreviation] J. Neurol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecule L1
  •  go-up   go-down


20. Hoshikawa S, Sano T, Yoshida T, Ito H, Oyama T, Fukuda T: Immunohistological analysis of HPV L1 capsid protein and p16 protein in low-grade dysplastic lesions of the uterine cervix. Pathol Res Pract; 2010 Dec 15;206(12):816-20
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistological analysis of HPV L1 capsid protein and p16 protein in low-grade dysplastic lesions of the uterine cervix.
  • Human papillomavirus (HPV) L1 capsid protein (L1) is associated with the productive phase of HPV infection.
  • However, the expression of L1 and its relationship to p16 expression, a surrogate marker for HPV infection, are unknown.
  • We examined the relationship between L1 and p16 expression in cervical intraepithelial neoplasia.
  • L1 positivity was not significant between each category.
  • The staining pattern was divided into the following four groups: L1-/p16-, L1+/p16-, L1+/p16+, L1-/p16+.
  • The L1-/p16- pattern was significantly associated with the regression nature in CIN1-2.
  • Some CIN3 cases showing a feature of L1+/p16+, which are still HPV-productive, are likely to exist.
  • The combination of both L1 and p16 may be useful in the evaluation of the progression risk of low-grade cervical dysplasia.
  • [MeSH-minor] Adolescent. Adult. Aged. DNA, Viral. Disease Progression. Female. Humans. Immunohistochemistry. Middle Aged. Papillomavirus Infections / complications. Papillomavirus Infections / pathology. Prognosis. Young Adult

  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier GmbH. All rights reserved.
  • (PMID = 20965668.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Capsid Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA, Viral; 0 / HPV L1 protein, Human papillomavirus; 0 / Oncogene Proteins, Viral
  •  go-up   go-down


21. Bolas-Fernández F, Dea-Ayuela MA, Connolly B, Robinson MW: Micro-environmental conditions modulate protein secretion and infectivity of the Trichinella spiralis L1 larva. Vet Parasitol; 2009 Feb 23;159(3-4):236-9
Hazardous Substances Data Bank. Carbon dioxide .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Micro-environmental conditions modulate protein secretion and infectivity of the Trichinella spiralis L1 larva.
  • After digestion of infected meat the free L1 of Trichinella spp. penetrate the intestinal mucosa where they moult to the mature adult stage.
  • For all culture media tested, infectivity of the L1 was preserved following incubation in anaerobic conditions.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19046809.001).
  • [ISSN] 1873-2550
  • [Journal-full-title] Veterinary parasitology
  • [ISO-abbreviation] Vet. Parasitol.
  • [Language] eng
  • [Grant] United Kingdom / Biotechnology and Biological Sciences Research Council / / C20267; United Kingdom / Biotechnology and Biological Sciences Research Council / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Culture Media; 0 / Helminth Proteins; 142M471B3J / Carbon Dioxide
  •  go-up   go-down


22. Ichikawa T, Li J, Dong X, Potts JD, Tang DQ, Li DS, Cui T: Ubiquitin carboxyl terminal hydrolase L1 negatively regulates TNFalpha-mediated vascular smooth muscle cell proliferation via suppressing ERK activation. Biochem Biophys Res Commun; 2010 Jan 1;391(1):852-6
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ubiquitin carboxyl terminal hydrolase L1 negatively regulates TNFalpha-mediated vascular smooth muscle cell proliferation via suppressing ERK activation.
  • We have recently demonstrated that a DUB of ubiquitin carboxyl terminal hydrolase L1 (UCH-L1) inhibits vascular lesion formation via suppressing inflammatory responses in vasculature.
  • Herein, we report that a posttranscriptional up-regulation of UCH-L1 provides a negative feedback to tumor necrosis factor alpha (TNFalpha)-mediated activation of extracellular signal-regulated kinases (ERK) and proliferation in vascular smooth muscle cells (VSMCs).
  • In rat adult VSMCs, adenoviral over-expression of UCH-L1 inhibited TNFalpha-induced activation of ERK and DNA synthesis.
  • In contrast, over-expression of UCH-L1 did not affect platelet derived growth factor (PDGF)-induced VSMC proliferation and activation of growth stimulating cascades including ERK.
  • TNFalpha hardly altered UCH-L1 mRNA expression and stability; however, up-regulated UCH-L1 protein expression via increasing UCH-L1 translation.
  • These results uncover a novel mechanism by which UCH-L1 suppresses vascular inflammation.

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 Elsevier Inc. All rights reserved.
  • [Cites] Nat Rev Cardiol. 2009 Jun;6(6):410-7 [19421244.001]
  • [Cites] Cardiovasc Res. 2008 Aug 1;79(3):360-76 [18487233.001]
  • [Cites] Cell Signal. 2009 Oct;21(10):1513-21 [19477270.001]
  • [Cites] PLoS One. 2009;4(8):e6764 [19707515.001]
  • [Cites] Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1843-50 [19592468.001]
  • [Cites] J Pathol. 2000 Feb;190(3):300-9 [10685064.001]
  • [Cites] Biochem Biophys Res Commun. 2000 Dec 29;279(3):938-41 [11162453.001]
  • [Cites] Blood. 2002 Jun 15;99(12):4443-8 [12036874.001]
  • [Cites] Nat Med. 2002 Nov;8(11):1249-56 [12411952.001]
  • [Cites] Circulation. 2003 Aug 26;108(8):1015-21 [12912810.001]
  • [Cites] J Cell Physiol. 2003 Dec;197(3):418-25 [14566971.001]
  • [Cites] Circ Res. 2004 Oct 29;95(9):858-66 [15514167.001]
  • [Cites] Circ Res. 1986 Apr;58(4):427-44 [3516443.001]
  • [Cites] Biochem Biophys Res Commun. 1995 Jun 15;211(2):686-93 [7794283.001]
  • [Cites] N Engl J Med. 1999 Jan 14;340(2):115-26 [9887164.001]
  • [Cites] Hypertension. 1999 Jan;33(1 Pt 2):183-9 [9931102.001]
  • [Cites] Cardiovasc Res. 2005 Feb 15;65(3):674-82 [15664394.001]
  • [Cites] Nat Rev Immunol. 2006 Jul;6(7):508-19 [16778830.001]
  • [Cites] Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2184-90 [17690318.001]
  • [Cites] J Pathol. 2008 Jan;214(2):149-60 [18161752.001]
  • [Cites] Circulation. 2008 Jan 29;117(4):e25-146 [18086926.001]
  • [Cites] Arterioscler Thromb Vasc Biol. 2008 May;28(5):812-9 [18276911.001]
  • [Cites] PLoS One. 2009;4(6):e5955 [19536331.001]
  • (PMID = 19945429.001).
  • [ISSN] 1090-2104
  • [Journal-full-title] Biochemical and biophysical research communications
  • [ISO-abbreviation] Biochem. Biophys. Res. Commun.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / P20 RR016434; United States / NCRR NIH HHS / RR / P20 RR016434-09; United States / NHLBI NIH HHS / HL / R01 HL033756; United States / NCRR NIH HHS / RR / 5P20 RR016434-09
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Necrosis Factor-alpha; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 3.1.2.15 / UCHL1 protein, human; EC 3.1.2.15 / Ubiquitin Thiolesterase
  • [Other-IDs] NLM/ NIHMS161809; NLM/ PMC3920551
  •  go-up   go-down


23. He XH, Xu LH, Liu Y: Identification of a novel splice variant of human PD-L1 mRNA encoding an isoform-lacking Igv-like domain. Acta Pharmacol Sin; 2005 Apr;26(4):462-8
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification of a novel splice variant of human PD-L1 mRNA encoding an isoform-lacking Igv-like domain.
  • AIM: To investigate the expression and regulation of PD-1 ligand 1 (PD-L1) in peripheral blood mononuclear cells (PBMC).
  • METHODS: The cDNA encoding human PD-L1 precursor was cloned from the total RNA extracted from the resting and phorbol dibutyrate plus ionomycin- or phytohemagglutinin-activated PBMC, by reverse transcription polymerase chain reaction (RT-PCR), and independent clones were sequenced and analyzed.
  • The PD-L1 gene expression in different PBMC was also analyzed by RT-PCR.
  • RESULTS: A novel human PD-L1 splice variant was identified from the activated PBMC.
  • In addition, the expression pattern of the PD-L1 splice variant was variable in different individuals and in different cellular status.
  • CONCLUSION: PD-L1 expression may be regulated at the posttranscriptional level through alternative splicing, and modulation of the PD-L1 isoform expression may influence the outcome of specific immune responses in the peripheral tissues.
  • [MeSH-minor] Adult. Amino Acid Sequence. Antigens, CD. Antigens, CD274. Base Sequence. Cloning, Molecular. Exons. Humans. Isomerism. K562 Cells. Leukocytes, Mononuclear / metabolism. Molecular Sequence Data. RNA, Messenger / biosynthesis. RNA, Messenger / genetics. Sequence Analysis, DNA. Transfection

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15780196.001).
  • [ISSN] 1671-4083
  • [Journal-full-title] Acta pharmacologica Sinica
  • [ISO-abbreviation] Acta Pharmacol. Sin.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD274; 0 / Antigens, CD80; 0 / CD274 protein, human; 0 / Immunoglobulin Variable Region; 0 / Membrane Glycoproteins; 0 / Peptides; 0 / RNA, Messenger
  •  go-up   go-down


24. Minosse C, Garbuglia AR, Lapa D, Sias C, Zaniratti MS, Capobianchi MR: Genetic variability in E6, E7 and L1 protein of HPV81 from HIV-1 positive women in Italy. New Microbiol; 2010 Jan;33(1):25-35
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic variability in E6, E7 and L1 protein of HPV81 from HIV-1 positive women in Italy.
  • The genetic variability of E6, E7 and L1 of HPV81 from HIV-1 positive women carrying multiple HPV infections was investigated by clonal analysis for E6 and E7.
  • The L1 sequence of a single clone from 5 study patients was also established.
  • Among L1 immune-related regions, BC loop presented T56N in 1/5, while FGb loop presented T287N in 4/5 patients.
  • [MeSH-minor] Adult. Amino Acid Sequence. Female. Humans. Italy. Middle Aged. Molecular Sequence Data. Protein Structure, Tertiary. Sequence Alignment. Young Adult

  • Genetic Alliance. consumer health - HIV.
  • MedlinePlus Health Information. consumer health - HPV.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20402411.001).
  • [ISSN] 1121-7138
  • [Journal-full-title] The new microbiologica
  • [ISO-abbreviation] New Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Capsid Proteins; 0 / HPV L1 protein, Human papillomavirus; 0 / Oncogene Proteins, Viral; 0 / Papillomavirus E7 Proteins
  •  go-up   go-down


25. Allory Y, Matsuoka Y, Bazille C, Christensen EI, Ronco P, Debiec H: The L1 cell adhesion molecule is induced in renal cancer cells and correlates with metastasis in clear cell carcinomas. Clin Cancer Res; 2005 Feb 1;11(3):1190-7
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The L1 cell adhesion molecule is induced in renal cancer cells and correlates with metastasis in clear cell carcinomas.
  • PURPOSE: The L1 cell adhesion molecule is overexpressed in many human carcinomas.
  • The objectives of the study were to provide a comprehensive description of L1 distribution in human kidney and to establish the prognostic relevance of L1 expression in renal cell carcinomas (RCC).
  • EXPERIMENTAL DESIGN: Using two antibodies to the extracellular part and the cytoplasmic domain, respectively, we first compared L1 expression in normal kidney and renal tumors of diverse histopathologic origin, then we studied L1 expression together with tumor stage, grade, molecular prognostic biomarkers, and metastatic behavior.
  • RESULTS: In normal kidney, L1 immunoreactive with both antibodies was expressed in all epithelial cells originating from the ureteric bud except for intercalated cells.
  • In renal tumors, L1 was mainly detected in those originating from cells that do not express L1 in the normal kidney [i.e., 33 of 72 clear cell RCC (ccRCC) and 25 of 88 papillary RCC (papRCC)].
  • Both in ccRCC and papRCC, L1 reacted only with the antibody to the extracellular domain, suggesting that the protein was truncated.
  • In these carcinomas, L1 expression was strongly correlated with Ki-67 proliferation index (ccRCC, P = 0.0059; papRCC, P = 0.0039), but only in ccRCC, the presence of L1 was associated with the risk of metastasis (P = 0.0121).
  • The L1(+)/cyclin D1(-) profile was an independent prognostic factor of metastasis occurrence in multivariate analysis (P = 0.0023).
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Neural Cell Adhesion Molecule L1 / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Cyclin D1 / analysis. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. In Situ Hybridization. Ki-67 Antigen / analysis. Kidney / chemistry. Kidney / metabolism. Male. Middle Aged. Neoplasm Metastasis. Prognosis. RNA, Messenger / genetics. RNA, Messenger / metabolism. Survival Analysis

  • Genetic Alliance. consumer health - Kidney cancer.
  • MedlinePlus Health Information. consumer health - Kidney Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15709188.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Neural Cell Adhesion Molecule L1; 0 / RNA, Messenger; 136601-57-5 / Cyclin D1
  •  go-up   go-down


26. Xiao Y, Zhang B: [Association of the ubiquitin carboxy-terminal hydrolase-L1 genetic polymorphism with the susceptibility of Parkinson's disease]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2008 Oct;25(5):586-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Association of the ubiquitin carboxy-terminal hydrolase-L1 genetic polymorphism with the susceptibility of Parkinson's disease].
  • OBJECTIVE: To study the association of two polymorphisms of ubiquitin carboxy-terminal hydrolase-L1 gene(UCH-L1), the 54C/A in exon 3 and the 277C/G in exon 4, with sporadic Parkinson's disease(PD) in Hans from North China.
  • METHODS: Polymerase chain reaction-restriction fragment length polymorphism was used to investigate the genotype and allele frequencies of the UCH-L1 C/A and C/G loci, in a case-control study including 75 sporadic PD and 100 randomly selected healthy control subjects.
  • RESULTS: (1)There was significant difference between PD patients and controls in the frequencies of UCH-L1 genotype and C/A allele(P<0.05).
  • The frequencies of allele A and genotype AA were both significantly lower in PD patients than that in the controls(P<0.05).(2)There was no polymorphism in the UCH-L1 C/G locus in all cases and controls.
  • CONCLUSION: (1)There might be association between the polymorphisms of UCH-L1 C/A locus and sporadic PD in Han population from North China.(2)There is no polymorphism in the UCH-L1 C/G locus in Hans from this region.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Asian Continental Ancestry Group / genetics. Ethnic Groups / genetics. Exons / genetics. Female. Gene Frequency. Genotype. Humans. Male. Middle Aged

  • MedlinePlus Health Information. consumer health - Parkinson's Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18841579.001).
  • [ISSN] 1003-9406
  • [Journal-full-title] Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
  • [ISO-abbreviation] Zhonghua Yi Xue Yi Chuan Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] EC 3.1.2.15 / UCHL1 protein, human; EC 3.1.2.15 / Ubiquitin Thiolesterase
  •  go-up   go-down


27. Huang MZ, Li HB, Nie XM, Wu XY, Jiang XM: An analysis on the combination expression of HPV L1 capsid protein and p16INK4a in cervical lesions. Diagn Cytopathol; 2010 Aug;38(8):573-8
International Agency for Research on Cancer - Screening Group. diagnostics - A practical manual on visual screening for cervical neoplasia .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An analysis on the combination expression of HPV L1 capsid protein and p16INK4a in cervical lesions.
  • The aims of this study were to detect the expression of HPV L1 capsid protein and p16(INK4a) in cervical lesions and to investigate the combination expression of HPV L1 capsid protein and p16(INK4a) in cervical lesions and its diagnostic efficiency in clinic.
  • Immunochemical method was used to detect the expression of HPV L1 capsid protein and p16(INK4a) in 169 cases of abnormal cytology.
  • L1 expression decreased (P < 0.001), but p16(INK4a) expression increased (P < 0.001) with histopathologic diagnosis increasing.
  • The expression rates of HPV L1 capsid protein, p16(INK4a), and L1(-)/p16(+) in cervical intraepithelial neoplasia (CIN)2, CIN3, and squamous-cell carcinoma were statistically different from those in CIN1 (P < 0.001).
  • The expressions of HPV L1 capsid protein, L1(+)/p16(+), L1(+)/p16(-), and L1(-)/p16(-) were negatively correlated with the severity of cervical lesions (P < 0.001), whereas the expressions of p16(INK4a) and L1(-)/p16(+) were positively correlated with the severity of cervical lesions (P < 0.001).
  • The specificity and A(Z) of combining L1 with p16 (INK4a) were statistically higher than L1 or p16 (INK4a) alone (P < 0.05).
  • L1 and p16(INK4a) are useful biomarkers for the early diagnosis of cervical lesions.
  • The combination of L1 and p16(INK4a) has a higher diagnostic accuracy than L1 or p16(INK4a) alone in diagnosis of cervical lesions.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Middle Aged. Staining and Labeling. Young Adult

  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19941368.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Capsid Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / HPV L1 protein, Human papillomavirus; 0 / Oncogene Proteins, Viral
  •  go-up   go-down


28. Nakamura Y, Lee S, Haddox CL, Weaver EJ, Lemmon VP: Role of the cytoplasmic domain of the L1 cell adhesion molecule in brain development. J Comp Neurol; 2010 Apr 1;518(7):1113-32
SciCrunch. Marmoset Gene list: Data: Gene Annotation .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of the cytoplasmic domain of the L1 cell adhesion molecule in brain development.
  • In vitro studies have shown that the L1 cytoplasmic domain (L1CD) is involved in L1 trafficking, neurite branching, signaling, and interactions with the cytoskeleton.
  • L1cam knockout (L1(KO)) mice have hydrocephalus, a small cerebellum, hyperfasciculation of corticothalamic tracts, and abnormal peripheral nerves.
  • In all mutant lines L1 protein is expressed and transported into the axon.
  • However, the expression of L1 protein in the adult is dramatically reduced in the two L1CD mutant lines that lack the ankyrin-binding region and they show defects in motor function.
  • Therefore, the L1CD is not responsible for the major defects observed in L1(KO) mice, yet it is required for continued L1 protein expression and motor function in the adult.

  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .
  • SciCrunch. The Antibody Registry: Reagent: Antibodies .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • [Cites] Hum Mol Genet. 1997;6(10):1625-32 [9300653.001]
  • [Cites] J Anat. 1997 Aug;191 ( Pt 2):229-44 [9306199.001]
  • [Cites] Nat Genet. 1997 Nov;17(3):346-9 [9354804.001]
  • [Cites] Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14602-7 [9405659.001]
  • [Cites] Curr Biol. 1998 Jan 1;8(1):26-33 [9427628.001]
  • [Cites] J Neurosci. 1998 May 15;18(10):3749-56 [9570805.001]
  • [Cites] Mol Cell Neurosci. 2000 Jan;15(1):1-10 [10662501.001]
  • [Cites] J Neurosci. 2000 May 15;20(10):3676-86 [10804209.001]
  • [Cites] Curr Opin Cell Biol. 2000 Oct;12(5):598-605 [10978896.001]
  • [Cites] Neuron. 2000 Aug;27(2):237-49 [10985345.001]
  • [Cites] Brain Res. 2001 Feb 9;891(1-2):247-52 [11164829.001]
  • [Cites] Brain Res Dev Brain Res. 2001 Jan 31;126(1):21-30 [11172883.001]
  • [Cites] Hum Mutat. 2001;18(1):1-12 [11438988.001]
  • [Cites] J Cell Biol. 2001 Aug 20;154(4):841-55 [11502758.001]
  • [Cites] J Cell Biol. 2001 Sep 17;154(6):1259-73 [11564762.001]
  • [Cites] J Cell Biol. 2002 Jun 24;157(7):1105-12 [12070130.001]
  • [Cites] J Cell Biol. 2002 Jun 24;157(7):1223-32 [12082080.001]
  • [Cites] Mol Cell Neurosci. 2002 Jul;20(3):367-81 [12139915.001]
  • [Cites] EMBO J. 2002 Dec 2;21(23):6348-57 [12456642.001]
  • [Cites] J Neurosci. 2003 Jan 1;23(1):277-86 [12514225.001]
  • [Cites] Neuron. 2003 Feb 20;37(4):611-24 [12597859.001]
  • [Cites] Adv Exp Med Biol. 2002;515:91-102 [12613546.001]
  • [Cites] Neurosci Lett. 2003 May 22;342(3):167-70 [12757891.001]
  • [Cites] J Comp Neurol. 2003 Sep 29;464(4):438-48 [12900915.001]
  • [Cites] J Cell Biol. 2003 Aug 18;162(4):719-30 [12925712.001]
  • [Cites] Front Biosci. 2003 Sep 1;8:s1210-25 [12957823.001]
  • [Cites] J Cell Biol. 2003 Sep 29;162(7):1317-28 [14517209.001]
  • [Cites] J Neurosci. 2003 Nov 12;23(32):10419-32 [14614101.001]
  • [Cites] Behav Brain Res. 2003 Dec 17;147(1-2):31-9 [14659567.001]
  • [Cites] J Cell Biol. 2003 Dec 8;163(5):1077-88 [14657231.001]
  • [Cites] Cereb Cortex. 2004 Feb;14(2):121-31 [14704209.001]
  • [Cites] J Neurosci Res. 2004 Jan 15;75(2):172-81 [14705138.001]
  • [Cites] Mol Biol Cell. 2004 Apr;15(4):2003-12 [14718570.001]
  • [Cites] Neurosci Res. 2004 Apr;48(4):471-5 [15041201.001]
  • [Cites] J Cell Biol. 2004 Apr12;165(1):145-54 [15067019.001]
  • [Cites] BMC Neurosci. 2003 Apr 16;4:7 [12697052.001]
  • [Cites] Dev Med Child Neurol. 1976 Aug;18(4):521-4 [955314.001]
  • [Cites] Nature. 1983 Sep 29-Oct 5;305(5933):427-30 [6621692.001]
  • [Cites] EMBO J. 1984 Jan;3(1):1-10 [6368220.001]
  • [Cites] Proc Natl Acad Sci U S A. 1985 Feb;82(4):1276-80 [3856258.001]
  • [Cites] J Med Genet. 1986 Feb;23(1):23-31 [3950933.001]
  • [Cites] Hum Mol Genet. 1998 Jun;7(6):999-1009 [9580664.001]
  • [Cites] J Neurosci. 1998 Jul 15;18(14):5311-21 [9651214.001]
  • [Cites] Eur J Neurosci. 1998 Feb;10(2):708-17 [9749732.001]
  • [Cites] Mol Cell Neurosci. 1998 Sep;12(1-2):48-55 [9770339.001]
  • [Cites] J Cell Biol. 1998 Nov 30;143(5):1305-15 [9832558.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2420-5 [10051657.001]
  • [Cites] J Cell Biol. 1999 Sep 6;146(5):1173-84 [10477768.001]
  • [Cites] J Neurosci. 2005 Jan 12;25(2):395-403 [15647482.001]
  • [Cites] Congenit Anom (Kyoto). 2005 Jun;45(2):67-9 [15904436.001]
  • [Cites] J Neurochem. 2005 Aug;94(4):1102-10 [16000162.001]
  • [Cites] Mol Cell Neurosci. 2005 Sep;30(1):131-6 [16039871.001]
  • [Cites] Curr Biol. 2006 Jan 10;16(1):12-23 [16401420.001]
  • [Cites] J Cell Sci. 2006 Apr 1;119(Pt 7):1341-9 [16537644.001]
  • [Cites] J Neurosci. 2006 May 10;26(19):5230-9 [16687515.001]
  • [Cites] Mol Biol Cell. 2006 Jun;17(6):2696-706 [16597699.001]
  • [Cites] Mol Cell Neurosci. 2006 Oct;33(2):214-26 [16952465.001]
  • [Cites] Nat Neurosci. 2007 Jan;10(1):19-26 [17189949.001]
  • [Cites] J Neurosurg. 2006 Nov;105(5 Suppl):403-12 [17328266.001]
  • [Cites] Curr Biol. 2007 Mar 20;17(6):562-8 [17331725.001]
  • [Cites] Nat Protoc. 2006;1(4):1671-9 [17487150.001]
  • [Cites] Mol Biol Cell. 2007 Aug;18(8):3131-43 [17538021.001]
  • [Cites] J Neurosci. 2008 Jan 2;28(1):177-88 [18171935.001]
  • [Cites] Mol Cell Neurosci. 2008 Mar;37(3):528-36 [18222703.001]
  • [Cites] J Cell Sci. 2008 May 1;121(Pt 9):1514-25 [18411247.001]
  • [Cites] J Comp Neurol. 2008 Oct 1;510(4):351-66 [18651636.001]
  • [Cites] J Neurosci Res. 2008 Sep;86(12):2602-14 [18478542.001]
  • [Cites] Mol Cell Neurosci. 2008 Sep;39(1):74-82 [18585463.001]
  • [Cites] Cell Mol Biol Lett. 2009;14(1):57-69 [18839070.001]
  • [Cites] Proc Natl Acad Sci U S A. 1987 Nov;84(21):7753-7 [3478724.001]
  • [Cites] Neuroscience. 1987 Oct;23(1):121-30 [3120034.001]
  • [Cites] J Cell Biol. 1988 Feb;106(2):487-503 [2448316.001]
  • [Cites] Cell. 1991 Jun 28;65(7):1153-63 [2065352.001]
  • [Cites] J Cell Biol. 1991 Nov;115(4):1113-26 [1720120.001]
  • [Cites] Am J Med Genet. 1992 Apr 15-May 1;43(1-2):408-14 [1605219.001]
  • [Cites] Neuron. 1994 Mar;12(3):675-90 [7512353.001]
  • [Cites] Cell Adhes Commun. 1993 Sep;1(2):177-90 [7521752.001]
  • [Cites] J Biol Chem. 1994 Nov 4;269(44):27163-6 [7961622.001]
  • [Cites] J Biol Chem. 1994 Dec 30;269(52):32886-95 [7806515.001]
  • [Cites] J Cell Biol. 1995 Dec;131(6 Pt 2):1881-91 [8557754.001]
  • [Cites] Mol Cell Neurosci. 1995 Oct;6(5):433-49 [8581314.001]
  • [Cites] J Cell Biol. 1996 Feb;132(3):475-85 [8636223.001]
  • [Cites] J Med Genet. 1996 Jan;33(1):59-65 [8825051.001]
  • [Cites] Neuron. 1996 Oct;17(4):587-93 [8893017.001]
  • [Cites] J Cell Biol. 1997 May 5;137(3):703-14 [9151675.001]
  • [Cites] Neuropediatrics. 1997 Jun;28(3):175-8 [9266556.001]
  • (PMID = 20127821.001).
  • [ISSN] 1096-9861
  • [Journal-full-title] The Journal of comparative neurology
  • [ISO-abbreviation] J. Comp. Neurol.
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / R01 HD039884; None / None / / R01 HD039884-06; United States / NICHD NIH HHS / HD / HD39884; United States / NICHD NIH HHS / HD / R01 HD039884-06
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecule L1
  • [Other-IDs] NLM/ NIHMS317564; NLM/ PMC3158433
  •  go-up   go-down


29. Cento V, Ciccozzi M, Ronga L, Perno CF, Ciotti M: Genetic diversity of human papillomavirus type 16 E6, E7, and L1 genes in Italian women with different grades of cervical lesions. J Med Virol; 2009 Sep;81(9):1627-34
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic diversity of human papillomavirus type 16 E6, E7, and L1 genes in Italian women with different grades of cervical lesions.
  • In this study, the presence of HPV 16 polymorphisms in the E6, E7, and L1 genes was investigated in relation to the presence of high-grade lesions.
  • The L1 gene showed 13 nucleotide changes leading to 11 amino acid substitutions.
  • Among these, the R364C and N367D are located at the base of the HI-loop of the L1 protein, considered to be the immunodominant epitope of HPV 16.
  • [MeSH-minor] Adult. Aged. Amino Acid Substitution / genetics. Cluster Analysis. DNA, Viral / chemistry. DNA, Viral / genetics. Female. Humans. Italy. Middle Aged. Molecular Epidemiology. Molecular Sequence Data. Mutation, Missense. Oncogene Proteins, Viral / genetics. Phylogeny. Sequence Homology. Young Adult

  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19626616.001).
  • [ISSN] 1096-9071
  • [Journal-full-title] Journal of medical virology
  • [ISO-abbreviation] J. Med. Virol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ FJ644954/ FJ644955/ FJ644956/ FJ644957/ FJ644958/ FJ644959/ FJ644960/ FJ644961/ FJ644962/ FJ644963/ FJ644964/ FJ644965/ FJ644966/ FJ644967/ FJ644968/ FJ644969/ FJ644970/ FJ644971/ FJ644972/ FJ644973/ FJ644974/ FJ644975/ FJ644976/ FJ644977/ FJ644978/ FJ644979/ FJ644980/ FJ644981/ FJ644982/ FJ644983/ FJ644984/ FJ644985/ FJ644986/ FJ644987/ FJ644988/ FJ644989/ FJ644990/ FJ644991/ FJ644992/ FJ644993/ FJ644994/ FJ644995/ FJ644996/ FJ644997/ FJ644998/ FJ644999/ FJ645000/ FJ645001/ FJ645002/ FJ645003/ FJ645004/ FJ645005/ FJ645006/ FJ645007/ FJ645008/ FJ645009/ FJ645010/ FJ645011/ FJ645012/ FJ645013/ FJ645014/ FJ645015/ FJ645016/ FJ645017/ FJ645018/ FJ645019/ FJ645020/ FJ645021/ FJ645022/ FJ645023/ FJ645024/ FJ645025/ FJ645026/ FJ645027/ FJ645028/ FJ645029/ FJ645030/ FJ645031/ FJ645032/ FJ645033/ FJ645034/ FJ645035/ FJ645036/ FJ645037/ FJ645038/ FJ645039/ FJ645040/ FJ645041/ FJ645042/ FJ645043/ FJ645044/ FJ645045/ FJ645046/ FJ645047/ FJ645048/ FJ645049/ FJ645050/ FJ645051/ FJ645052/ FJ645053/ FJ645054/ FJ645055/ FJ645056/ FJ645057/ FJ645058/ FJ645059/ FJ645060/ FJ645061
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral; 0 / Oncogene Proteins, Viral
  •  go-up   go-down


30. Allory Y, Audard V, Fontanges P, Ronco P, Debiec H: The L1 cell adhesion molecule is a potential biomarker of human distal nephron injury in acute tubular necrosis. Kidney Int; 2008 Mar;73(6):751-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The L1 cell adhesion molecule is a potential biomarker of human distal nephron injury in acute tubular necrosis.
  • The L1 cell adhesion molecule (CD171) is a multidomain membrane glycoprotein of the immunoglobulin superfamily.
  • We evaluated its expression in human acute kidney injury and assessed its use as a tissue and urinary marker of acute tubular injury.
  • Using immunohistochemical studies with antibodies to the extracellular or cytoplasmic domains, we compared L1 expression in normal kidneys in 24 biopsies taken from patients with acute tubular necrosis.
  • L1 was found at the basolateral and the lateral membrane in all epithelial cells of the collecting duct in the normal kidney except for intercalated cells.
  • In acute tubular necrosis, L1 lost its polarized distribution being found in both the basolateral and apical domains of the collecting duct.
  • Apically expressed L1 found only when the cytoplasmic domain antibody was used in biopsy specimens of patients with acute tubular necrosis.
  • The levels of urinary L1, normalized for creatinine, were significantly higher in all 24 patients with acute tubular necrosis compared to five patients with prerenal azotemia or to six patients with other causes of acute kidney injury.
  • Our study shows that a soluble form of human L1 can be detected in the urine of patients with acute tubular necrosis and that this may be a marker of distal nephron injury.
  • [MeSH-major] Biomarkers / urine. Kidney Tubular Necrosis, Acute / diagnosis. Neural Cell Adhesion Molecule L1 / analysis
  • [MeSH-minor] Adolescent. Adult. Aged. Cell Membrane / chemistry. Cell Polarity. Female. Humans. Male. Middle Aged. Nephrons / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18059459.001).
  • [ISSN] 1523-1755
  • [Journal-full-title] Kidney international
  • [ISO-abbreviation] Kidney Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Neural Cell Adhesion Molecule L1
  •  go-up   go-down


31. Urquiza M, Sánchez R, Amaya J, León S, Acosta J, Patarroyo MA, Camargo M, Patarroyo ME: Specificity of L1 peptides versus virus-like particles for detection of human papillomavirus-positive cervical lesions in females attending Engativa Hospital, Bogota, Colombia. J Clin Microbiol; 2008 Nov;46(11):3714-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Specificity of L1 peptides versus virus-like particles for detection of human papillomavirus-positive cervical lesions in females attending Engativa Hospital, Bogota, Colombia.
  • A serological test for the detection of human papillomavirus (HPV) infection in females at risk of developing cervical cancer could be based on conserved L1 peptides with low levels of antigenicity specifically recognized by antibodies from patients with cervical lesions infected with high-risk HPV (HR-HPV) types.
  • The aim was to assess the ability of L1 peptides 18283, 18294, and 18301 compared with the ability of virus-like particles (VLPs) to identify these infections in females.
  • [MeSH-minor] Adolescent. Adult. Aged. Colombia. DNA, Viral / isolation & purification. Female. Hospitals. Humans. Immunologic Tests / methods. Middle Aged. Papanicolaou Test. Sensitivity and Specificity. Vaginal Smears

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Clin Microbiol. 2000 Feb;38(2):688-95 [10655368.001]
  • [Cites] Biochem Biophys Res Commun. 2005 Jun 24;332(1):224-32 [15896321.001]
  • [Cites] J Clin Virol. 2000 Oct;19(1-2):1-5 [11091143.001]
  • [Cites] Int J Cancer. 2002 Feb 20;97(6):796-803 [11857357.001]
  • [Cites] Clin Diagn Lab Immunol. 2002 May;9(3):577-82 [11986263.001]
  • [Cites] Dermatol Clin. 2002 Apr;20(2):315-31 [12120445.001]
  • [Cites] EMBO J. 2002 Sep 16;21(18):4754-62 [12234916.001]
  • [Cites] Rev Inst Med Trop Sao Paulo. 2003 May-Jun;45(3):131-5 [12870061.001]
  • [Cites] J Virol. 2003 Nov;77(21):11625-32 [14557648.001]
  • [Cites] Gynecol Oncol. 2004 Mar;92(3):873-80 [14984955.001]
  • [Cites] J Clin Virol. 2004 Aug;30(4):302-8 [15163418.001]
  • [Cites] J Gen Virol. 2004 Sep;85(Pt 9):2643-50 [15302958.001]
  • [Cites] Br J Cancer. 2004 Aug 31;91(5):942-53 [15292939.001]
  • [Cites] Virology. 1985 Aug;145(1):181-5 [2990099.001]
  • [Cites] Proc Natl Acad Sci U S A. 1985 Aug;82(15):5131-5 [2410914.001]
  • [Cites] J Adolesc Health. 2005 Dec;37(6 Suppl):S3-9 [16310138.001]
  • [Cites] Cancer Lett. 2006 Jan 18;231(2):309-13 [16399232.001]
  • [Cites] J Virol. 2006 May;80(10):4664-72 [16641259.001]
  • [Cites] Obstet Gynecol Surv. 2006 Jun;61(6 Suppl 1):S3-14 [16729902.001]
  • [Cites] Cancer. 2006 Oct 25;108(5):288-97 [16952155.001]
  • [Cites] Science. 1985 Dec 20;230(4732):1350-4 [2999980.001]
  • [Cites] Science. 1988 Jan 29;239(4839):487-91 [2448875.001]
  • [Cites] Biometrics. 1989 Mar;45(1):255-68 [2720055.001]
  • [Cites] Int J Cancer. 1992 Feb 1;50(3):349-55 [1310487.001]
  • [Cites] J Infect Dis. 1995 Jul;172(1):19-24 [7797910.001]
  • [Cites] J Natl Cancer Inst. 1995 Sep 20;87(18):1365-71 [7658497.001]
  • [Cites] Eur J Cancer. 1996 May;32A(5):872-6 [9081369.001]
  • [Cites] J Clin Microbiol. 1996 Sep;34(9):2095-100 [8862564.001]
  • [Cites] J Infect Dis. 1996 Nov;174(5):927-36 [8896492.001]
  • [Cites] J Gen Virol. 1995 Apr;76 ( Pt 4):1057-62 [9049358.001]
  • [Cites] Clin Diagn Lab Immunol. 1997 Mar;4(2):122-6 [9067643.001]
  • [Cites] J Natl Cancer Inst. 1997 May 7;89(9):630-8 [9150187.001]
  • [Cites] J Infect Dis. 1998 Jun;177(6):1710-4 [9607854.001]
  • [Cites] J Clin Microbiol. 1998 Jul;36(7):2046-51 [9650960.001]
  • [Cites] J Clin Virol. 2005 Mar;32 Suppl 1:S16-24 [15753008.001]
  • [Cites] Int J Cancer. 2005 May 20;115(1):114-20 [15688414.001]
  • [Cites] J Infect Dis. 2000 Jun;181(6):1911-9 [10837170.001]
  • (PMID = 18799706.001).
  • [ISSN] 1098-660X
  • [Journal-full-title] Journal of clinical microbiology
  • [ISO-abbreviation] J. Clin. Microbiol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Viral; 0 / DNA, Viral; 0 / Viral Proteins; 0 / Virosomes
  • [Other-IDs] NLM/ PMC2576595
  •  go-up   go-down


32. Block SL, Nolan T, Sattler C, Barr E, Giacoletti KE, Marchant CD, Castellsagué X, Rusche SA, Lukac S, Bryan JT, Cavanaugh PF Jr, Reisinger KS, Protocol 016 Study Group: Comparison of the immunogenicity and reactogenicity of a prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in male and female adolescents and young adult women. Pediatrics; 2006 Nov;118(5):2135-45
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of the immunogenicity and reactogenicity of a prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in male and female adolescents and young adult women.
  • OBJECTIVE: Prophylactic vaccination of 16- to 23-year-old females with a quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like particle vaccine has been shown to prevent type-specific human papillomavirus infection and associated clinical disease.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Antibodies, Viral / blood. Child. Female. Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18. Humans. Male. Papillomaviridae / immunology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17079588.001).
  • [ISSN] 1098-4275
  • [Journal-full-title] Pediatrics
  • [ISO-abbreviation] Pediatrics
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Viral; 0 / Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; 0 / Papillomavirus Vaccines; 0 / Viral Vaccines
  •  go-up   go-down


33. Trabattoni D, Saresella M, Pacei M, Marventano I, Mendozzi L, Rovaris M, Caputo D, Borelli M, Clerici M: Costimulatory pathways in multiple sclerosis: distinctive expression of PD-1 and PD-L1 in patients with different patterns of disease. J Immunol; 2009 Oct 15;183(8):4984-93
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Costimulatory pathways in multiple sclerosis: distinctive expression of PD-1 and PD-L1 in patients with different patterns of disease.
  • T lymphocytes costimulatory molecules, including CD80, CD86, CD28, CTLA4, PD-1, PD-L1, and B7-H3, are associated with the preferential production of pro- or anti-inflammatory cytokines.
  • We analyzed the expression of these molecules and myelin basic protein (MBP)-specific IL-10 and IFN-gamma production in patients with multiple sclerosis (MS) with relapsing-remitting acute (AMS, n = 40) or stable (SMS, n = 38).
  • MBP-specific and PD-1-expressing T lymphocytes, PD-L1-expressing CD19(+) cells, and PD-L1(+)/IL-10(+)/CD14(+) and CD19(+) cells were significantly augmented in SMS patients.
  • B7-H3 expression and IFN-gamma production were comparable in all individuals but the PD-L1(+)/IL-10(+) over B7-H3(+)/IFN-gamma(+) ratio was significantly lower in AMS compared with SMS patients.
  • Finally, PD-L1 expression on immune cells was reduced in treated patients, suggesting that therapy-induced disease remission is not associated with the modulation of the expression of this molecule.
  • The PD-1/PD-L1 pathway plays an important role in modulating immune functions in MS patients; monitoring and targeting these proteins could offer diagnostic and therapeutic advantages.
  • [MeSH-minor] Adult. Antigens, CD274. Antigens, CD28 / immunology. Antigens, CD28 / metabolism. Antigens, CD80 / immunology. Antigens, CD80 / metabolism. Antigens, CD86 / immunology. Antigens, CD86 / metabolism. Apoptosis / immunology. B7 Antigens. CTLA-4 Antigen. Female. Humans. Interferon-gamma / immunology. Interferon-gamma / metabolism. Interleukin-10 / immunology. Interleukin-10 / metabolism. Male. Middle Aged. Myelin Basic Protein / immunology. Myelin Basic Protein / metabolism. Oncogene Protein v-akt / immunology. Oncogene Protein v-akt / metabolism. Peptides / immunology. Programmed Cell Death 1 Receptor. Receptors, Immunologic / immunology. Receptors, Immunologic / metabolism. Signal Transduction / immunology

  • Genetic Alliance. consumer health - Multiple Sclerosis.
  • MedlinePlus Health Information. consumer health - Multiple Sclerosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19794071.001).
  • [ISSN] 1550-6606
  • [Journal-full-title] Journal of immunology (Baltimore, Md. : 1950)
  • [ISO-abbreviation] J. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD274; 0 / Antigens, CD28; 0 / Antigens, CD80; 0 / Antigens, CD86; 0 / Apoptosis Regulatory Proteins; 0 / B7 Antigens; 0 / CD274 protein, human; 0 / CD276 protein, human; 0 / CTLA-4 Antigen; 0 / CTLA4 protein, human; 0 / Myelin Basic Protein; 0 / PDCD1 protein, human; 0 / Peptides; 0 / Programmed Cell Death 1 Receptor; 0 / Receptors, Immunologic; 130068-27-8 / Interleukin-10; 82115-62-6 / Interferon-gamma; EC 2.7.11.1 / Oncogene Protein v-akt
  •  go-up   go-down


34. Lavdas AA, Chen J, Papastefanaki F, Chen S, Schachner M, Matsas R, Thomaidou D: Schwann cells engineered to express the cell adhesion molecule L1 accelerate myelination and motor recovery after spinal cord injury. Exp Neurol; 2010 Jan;221(1):206-16
Hazardous Substances Data Bank. BROMODEOXYURIDINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Schwann cells engineered to express the cell adhesion molecule L1 accelerate myelination and motor recovery after spinal cord injury.
  • In this study, we used retroviral transduction to genetically modify SCs from transgenic GFP-mice in order to overexpress the cell adhesion molecule L1, a protein promoting neurite outgrowth and implicated in myelination.
  • SCs transduced to express L1 or its chimeric secreted form L1-Fc were mixed and grafted rostrally to the lesion site of adult mice immediately after spinal cord compression injury.
  • Our results indicate that 3 weeks postoperatively, but not thereafter, mice transplanted with L1/L1-Fc-expressing SCs exhibited faster locomotor recovery as compared to animals which received SCs transduced with a control vector or no cells at all.
  • Moreover, increased sprouting of serotonergic fibers into and across the lesion site was observed in the L1/L1-Fc group as compared with controls.
  • Our results suggest that transplantation of L1-overexpressing SCs enhances early events in spinal cord repair after injury and may be considered in combinatorial strategies together with other regeneration-promoting molecules.
  • [MeSH-major] Cell Transplantation / methods. Nerve Fibers, Myelinated / physiology. Nerve Regeneration / physiology. Neural Cell Adhesion Molecule L1 / metabolism. Schwann Cells / transplantation. Spinal Cord Injuries

  • MedlinePlus Health Information. consumer health - Spinal Cord Injuries.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19909742.001).
  • [ISSN] 1090-2430
  • [Journal-full-title] Experimental neurology
  • [ISO-abbreviation] Exp. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecule L1; 147336-22-9 / Green Fluorescent Proteins; 333DO1RDJY / Serotonin; G34N38R2N1 / Bromodeoxyuridine
  •  go-up   go-down


35. Hildesheim A, Herrero R, Wacholder S, Rodriguez AC, Solomon D, Bratti MC, Schiller JT, Gonzalez P, Dubin G, Porras C, Jimenez SE, Lowy DR, Costa Rican HPV Vaccine Trial Group: Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection: a randomized trial. JAMA; 2007 Aug 15;298(7):743-53
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection: a randomized trial.
  • INTERVENTION: Participants were randomly assigned to receive 3 doses of a bivalent HPV-16/18 L1 protein viruslike particle AS04 candidate vaccine (n = 1088) or a control hepatitis A vaccine (n = 1101) over 6 months.

  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] JAMA. 2007 Aug 15;298(7):805-6 [17699015.001]
  • (PMID = 17699008.001).
  • [ISSN] 1538-3598
  • [Journal-full-title] JAMA
  • [ISO-abbreviation] JAMA
  • [Language] ENG
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT00128661
  • [Grant] United States / NCI NIH HHS / CP / N01-CP-11005
  • [Publication-type] Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral; 0 / Papillomavirus Vaccines
  •  go-up   go-down


36. Dauner JG, Pan Y, Hildesheim A, Harro C, Pinto LA: Characterization of the HPV-specific memory B cell and systemic antibody responses in women receiving an unadjuvanted HPV16 L1 VLP vaccine. Vaccine; 2010 Jul 26;28(33):5407-13
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization of the HPV-specific memory B cell and systemic antibody responses in women receiving an unadjuvanted HPV16 L1 VLP vaccine.
  • Human papillomavirus (HPV)-specific antibodies are proposed to be the correlate of protection afforded by HPV L1 virus-like particle (VLP) vaccines.
  • Here, we have adapted a generalized memory B cell ELISPOT to the HPV16 system and expanded the analysis of the systemic antibody response to include an avidity measurement of HPV L1 VLP-specific antibodies.
  • This is the first comprehensive study to correlate a variety of humoral aspects potentially associated with protective immunity following vaccination with a HPV16 L1 VLP vaccine.

  • MedlinePlus Health Information. consumer health - Immunization.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • [Cites] J Immunol Methods. 1997 Jun 23;205(1):67-72 [9236916.001]
  • [Cites] Science. 2002 Dec 13;298(5601):2199-202 [12481138.001]
  • [Cites] Gynecol Oncol. 2008 Sep;110(3 Suppl 1):S1-10 [18653222.001]
  • [Cites] J Infect Dis. 2008 Oct 1;198(7):1055-61 [18729782.001]
  • [Cites] Hum Vaccin. 2008 Nov-Dec;4(6):425-34 [18948732.001]
  • [Cites] Hum Vaccin. 2009 Oct;5(10):705-19 [19684472.001]
  • [Cites] J Natl Cancer Inst. 2001 Feb 21;93(4):284-92 [11181775.001]
  • [Cites] Vaccine. 2001 Mar 21;19(17-19):2280-5 [11257348.001]
  • [Cites] J Infect Dis. 2001 Nov 1;184(9):1211-5 [11598848.001]
  • [Cites] J Infect Dis. 2003 Jul 15;188(2):327-38 [12854090.001]
  • [Cites] J Immunol. 2003 Nov 15;171(10):4969-73 [14607890.001]
  • [Cites] J Immunol Methods. 2004 Mar;286(1-2):111-22 [15087226.001]
  • [Cites] J Infect Dis. 2004 Oct 1;190(7):1228-36 [15346332.001]
  • [Cites] J Clin Immunol. 1988 May;8(3):214-21 [3292566.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12180-4 [1334560.001]
  • [Cites] J Virol. 1993 Dec;67(12):6929-36 [8230414.001]
  • [Cites] J Clin Lab Anal. 1994;8(1):16-21 [8164106.001]
  • [Cites] J Virol. 1995 Jun;69(6):3959-63 [7745754.001]
  • [Cites] J Pathol. 1999 Sep;189(1):12-9 [10451482.001]
  • [Cites] J Infect Dis. 1999 Oct;180(4):1390-3 [10479180.001]
  • [Cites] Lancet. 2004 Nov 13-19;364(9447):1757-65 [15541448.001]
  • [Cites] Vaccine. 2006 Aug 14;24(33-34):5937-49 [16828940.001]
  • [Cites] J Virol. 2006 Oct;80(19):9577-85 [16973561.001]
  • [Cites] Scand J Immunol. 2006 Nov;64(5):536-43 [17032247.001]
  • [Cites] Clin Vaccine Immunol. 2007 May;14(5):644-7 [17344342.001]
  • [Cites] CMAJ. 2007 Aug 28;177(5):469-79 [17671238.001]
  • [Cites] Lancet. 2007 Sep 8;370(9590):890-907 [17826171.001]
  • [Cites] J Infect Dis. 2007 Nov 1;196(9):1339-45 [17922398.001]
  • [Cites] Clin Vaccine Immunol. 2007 Oct;14(10):1362-9 [17699836.001]
  • [Cites] J Immunol. 2008 Feb 15;180(4):2165-73 [18250423.001]
  • [Cites] Nature. 2008 May 29;453(7195):667-71 [18449194.001]
  • [Cites] Vaccine. 2008 Jul 4;26(29-30):3608-16 [18541349.001]
  • [Cites] PLoS One. 2008;3(8):e2975 [18714352.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11553-7 [8524802.001]
  • [Cites] Virology. 1996 Sep 1;223(1):174-84 [8806551.001]
  • [Cites] J Virol. 1997 Aug;71(8):6247-52 [9223527.001]
  • [Cites] Vaccine. 2002 Jun 7;20(19-20):2592-6 [12057617.001]
  • [Cites] N Engl J Med. 2002 Nov 21;347(21):1645-51 [12444178.001]
  • [Cites] Immunity. 1998 Mar;8(3):363-72 [9529153.001]
  • (PMID = 20591543.001).
  • [ISSN] 1873-2518
  • [Journal-full-title] Vaccine
  • [ISO-abbreviation] Vaccine
  • [Language] ENG
  • [Grant] United States / CCR NIH HHS / RC / HHSN261200800001C; United States / NCI NIH HHS / CA / HHSN261200800001E; United States / Intramural NIH HHS / / ZIA CP010177-09
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies, Neutralizing; 0 / Antibodies, Viral; 0 / Papillomavirus Vaccines
  • [Other-IDs] NLM/ NIHMS218186; NLM/ PMC2913111
  •  go-up   go-down


37. Harper DM, Franco EL, Wheeler CM, Moscicki AB, Romanowski B, Roteli-Martins CM, Jenkins D, Schuind A, Costa Clemens SA, Dubin G, HPV Vaccine Study group: Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial. Lancet; 2006 Apr 15;367(9518):1247-55
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial.
  • Our aim was to assess the long-term efficacy, immunogenicity, and safety of a bivalent HPV-16/18 L1 virus-like particle AS04 vaccine against incident and persistent infection with HPV 16 and HPV 18 and their associated cytological and histological outcomes.
  • INTERPRETATION: Up to 4.5 years, the HPV-16/18 L1 virus-like particle AS04 vaccine is highly immunogenic and safe, and induces a high degree of protection against HPV-16/18 infection and associated cervical lesions.
  • [MeSH-minor] Adult. Cervical Intraepithelial Neoplasia / etiology. Cervical Intraepithelial Neoplasia / prevention & control. Double-Blind Method. Female. Follow-Up Studies. Humans. Multicenter Studies as Topic. Randomized Controlled Trials as Topic. Time Factors. Uterine Cervical Neoplasms / etiology. Uterine Cervical Neoplasms / prevention & control


38. Ayyub M, Ali W, Anwar M, Waqar A, Khan MN, Ijaz A, Hussain T, Hussain S: Efficacy and adverse effects of oral iron chelator deferiprone (l1, 1,2- dimethyl-3-hydroxypyrid-4-one) in patients with beta thalassaemia major in Pakistan. J Ayub Med Coll Abbottabad; 2005 Oct-Dec;17(4):12-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Efficacy and adverse effects of oral iron chelator deferiprone (l1, 1,2- dimethyl-3-hydroxypyrid-4-one) in patients with beta thalassaemia major in Pakistan.
  • BACKGROUND: Deferiprone (DFP,L1) is a bidentate oral iron chelator which binds to iron in a 3:1 ratio.
  • [MeSH-minor] Adolescent. Adult. Child. Demography. Female. Humans. Male. Pakistan. Prospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16599026.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 0 / Iron Chelating Agents; 0 / Pyridones; 2BTY8KH53L / deferiprone; 9007-73-2 / Ferritins
  •  go-up   go-down


39. Joura EA, Leodolter S, Hernandez-Avila M, Wheeler CM, Perez G, Koutsky LA, Garland SM, Harper DM, Tang GW, Ferris DG, Steben M, Jones RW, Bryan J, Taddeo FJ, Bautista OM, Esser MT, Sings HL, Nelson M, Boslego JW, Sattler C, Barr E, Paavonen J: Efficacy of a quadrivalent prophylactic human papillomavirus (types 6, 11, 16, and 18) L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: a combined analysis of three randomised clinical trials. Lancet; 2007 May 19;369(9574):1693-702
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Efficacy of a quadrivalent prophylactic human papillomavirus (types 6, 11, 16, and 18) L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: a combined analysis of three randomised clinical trials.
  • METHODS: 18 174 women (16-26 years) were enrolled and randomised to receive either quadrivalent HPV6/11/16/18 L1 virus-like-particle vaccine or placebo at day 1, and months 2 and 6.
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Multicenter Studies as Topic. Randomized Controlled Trials as Topic


40. März M, Chapouton P, Diotel N, Vaillant C, Hesl B, Takamiya M, Lam CS, Kah O, Bally-Cuif L, Strähle U: Heterogeneity in progenitor cell subtypes in the ventricular zone of the zebrafish adult telencephalon. Glia; 2010 May;58(7):870-88
ZFIN. ZFIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Heterogeneity in progenitor cell subtypes in the ventricular zone of the zebrafish adult telencephalon.
  • The zebrafish has become a new model for adult neurogenesis, owing to its abundant neurogenic areas in most brain subdivisions.
  • In this work, we studied the expression of various transgenic or immunocytochemical markers for glial cells (gfap:gfp, cyp19a1b:gfp, BLBP, and S100beta), progenitors (nestin:gfp and Sox2), and neuroblasts (PSA-NCAM) in cycling progenitors of the adult zebrafish telencephalon (identified by expression of proliferating cell nuclear antigen (PCNA), MCM5, or bromodeoxyuridine incorporation).
  • We demonstrate the existence of distinct populations of dividing cells at the adult telencephalic VZ.
  • On the basis of the marker gene expression and distinct cell morphologies, we propose a classification for the dividing cell states at the zebrafish adult telencephalic VZ.
  • [MeSH-minor] Animals. Animals, Genetically Modified. Biomarkers / analysis. Biomarkers / metabolism. Cell Division / physiology. Cell Proliferation. Intermediate Filament Proteins / analysis. Intermediate Filament Proteins / genetics. Intermediate Filament Proteins / metabolism. Lateral Ventricles. Nerve Tissue Proteins / analysis. Nerve Tissue Proteins / genetics. Nerve Tissue Proteins / metabolism. Nestin. Neural Cell Adhesion Molecule L1 / analysis. Neural Cell Adhesion Molecule L1 / genetics. Neural Cell Adhesion Molecule L1 / metabolism. Neuroglia / cytology. Neuroglia / metabolism. Neurons / cytology. Neurons / metabolism. SOX Transcription Factors / analysis. SOX Transcription Factors / genetics. SOX Transcription Factors / metabolism. Sialic Acids / analysis. Sialic Acids / genetics. Sialic Acids / metabolism. Zebrafish Proteins / analysis. Zebrafish Proteins / genetics. Zebrafish Proteins / metabolism

  • MedlinePlus Health Information. consumer health - Stem Cells.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20155821.001).
  • [ISSN] 1098-1136
  • [Journal-full-title] Glia
  • [ISO-abbreviation] Glia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Intermediate Filament Proteins; 0 / Nerve Tissue Proteins; 0 / Nestin; 0 / Neural Cell Adhesion Molecule L1; 0 / SOX Transcription Factors; 0 / Sialic Acids; 0 / Sox2 protein, zebrafish; 0 / Zebrafish Proteins; 0 / polysialyl neural cell adhesion molecule
  •  go-up   go-down


41. Andersen DC, Jensen L, Schrøder HD, Jensen CH: "The preadipocyte factor" DLK1 marks adult mouse adipose tissue residing vascular cells that lack in vitro adipogenic differentiation potential. FEBS Lett; 2009 Sep 3;583(17):2947-53
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] "The preadipocyte factor" DLK1 marks adult mouse adipose tissue residing vascular cells that lack in vitro adipogenic differentiation potential.
  • Delta-like 1 (Dlk1) is expressed in 3T3-L1 preadipocytes and has frequently been referred to as "the" preadipocyte marker, yet the phenotype of DLK1(+) cells in adipose tissue remains undetermined.
  • Herein, we demonstrate that DLK1(+) cells encompass around 1-2% of the adult mouse adipose stromal vascular fraction (SVF).
  • [MeSH-minor] 3T3-L1 Cells. Animals. Cell Separation. Cells, Cultured. Endothelium, Vascular / cytology. Female. Flow Cytometry. Mice. Neovascularization, Physiologic. Stromal Cells / cytology. Stromal Cells / metabolism

  • COS Scholar Universe. author profiles.
  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19665021.001).
  • [ISSN] 1873-3468
  • [Journal-full-title] FEBS letters
  • [ISO-abbreviation] FEBS Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Dlk1 protein, mouse; 0 / Intercellular Signaling Peptides and Proteins
  •  go-up   go-down


42. Peelle MW, Boachie-Adjei O, Charles G, Kanazawa Y, Mesfin A: Lumbar curve response to selective thoracic fusion in adult idiopathic scoliosis. Spine J; 2008 Nov-Dec;8(6):897-903
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lumbar curve response to selective thoracic fusion in adult idiopathic scoliosis.
  • BACKGROUND CONTEXT: To date, no study has critically examined the radiographic characteristics of the lumbar curve after selective thoracic fusion for the adult idiopathic scoliosis patient population.
  • PURPOSE: To evaluate the radiographic response of the lumbar curve to selective thoracic fusion in the adult scoliosis population with correlative clinical outcomes.
  • All patients underwent selective thoracic posterior fusion with end-instrumented vertebra at T11 (1), T12 (7), L1 (14), and L2 (8).
  • CONCLUSIONS: The lumbar curve response in adult, selective thoracic scoliosis surgery is characterized by 1) moderate correction but less than the bending film Cobb;.
  • Good clinical outcomes can be achieved with posterior translational instrumentation in adult scoliosis patients.
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Postoperative Complications. Retrospective Studies. Treatment Outcome. Young Adult

  • Genetic Alliance. consumer health - Scoliosis.
  • MedlinePlus Health Information. consumer health - Scoliosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18261962.001).
  • [ISSN] 1529-9430
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


43. Peretto P, Giachino C, Aimar P, Fasolo A, Bonfanti L: Chain formation and glial tube assembly in the shift from neonatal to adult subventricular zone of the rodent forebrain. J Comp Neurol; 2005 Jul 11;487(4):407-27
University of Turin Instituional Repository AperTO. Full Text from .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chain formation and glial tube assembly in the shift from neonatal to adult subventricular zone of the rodent forebrain.
  • The two distinct compartments of the adult rodent forebrain SVZ, astrocytic glial tubes and chains of migrating cells, are not distinguishable in the embryonic and early postnatal counterpart.
  • In this study we analyzed the SVZ of mice and rats around birth and throughout different postnatal stages, describing molecular and morphological changes which lead to the typical structural arrangement of adult SVZ.
  • The attainment of an adult SVZ compartmentalization, on the other hand, seems linked to the pattern of expression of adhesion and extracellular matrix molecules.
  • [MeSH-minor] Animals. Animals, Newborn. Bromodeoxyuridine / metabolism. Carrier Proteins / metabolism. Cell Count / methods. Cell Differentiation / physiology. Connexin 43 / metabolism. Embryo, Mammalian. Fatty Acid-Binding Proteins. Fructose-Bisphosphate Aldolase / metabolism. Gene Expression Regulation, Developmental / physiology. Glial Fibrillary Acidic Protein / metabolism. Immunohistochemistry / methods. Intermediate Filament Proteins / metabolism. Mice. Microscopy, Electron, Transmission / methods. Microscopy, Immunoelectron / methods. Models, Biological. Nerve Growth Factors / metabolism. Nerve Tissue Proteins / metabolism. Nestin. Neural Cell Adhesion Molecule L1 / metabolism. Phosphopyruvate Hydratase / metabolism. Rats. Rats, Wistar. S100 Calcium Binding Protein beta Subunit. S100 Proteins / metabolism. Sialic Acids / metabolism. Tenascin / metabolism. Tubulin / metabolism. Vimentin / metabolism

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. BROMODEOXYURIDINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2005 Wiley-Liss, Inc.
  • (PMID = 15906315.001).
  • [ISSN] 0021-9967
  • [Journal-full-title] The Journal of comparative neurology
  • [ISO-abbreviation] J. Comp. Neurol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carrier Proteins; 0 / Connexin 43; 0 / Fabp7 protein, rat; 0 / Fatty Acid-Binding Proteins; 0 / Glial Fibrillary Acidic Protein; 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Nerve Growth Factors; 0 / Nerve Tissue Proteins; 0 / Nes protein, mouse; 0 / Nes protein, rat; 0 / Nestin; 0 / Neural Cell Adhesion Molecule L1; 0 / S100 Calcium Binding Protein beta Subunit; 0 / S100 Proteins; 0 / Sialic Acids; 0 / Tenascin; 0 / Tubulin; 0 / Vimentin; 0 / polysialyl neural cell adhesion molecule; EC 4.1.2.13 / Fructose-Bisphosphate Aldolase; EC 4.2.1.11 / Phosphopyruvate Hydratase; G34N38R2N1 / Bromodeoxyuridine
  •  go-up   go-down


44. Park JH, Enikolopov G: Transient elevation of adult hippocampal neurogenesis after dopamine depletion. Exp Neurol; 2010 Apr;222(2):267-76
Hazardous Substances Data Bank. BROMODEOXYURIDINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transient elevation of adult hippocampal neurogenesis after dopamine depletion.
  • The dentate gyrus (DG), a site of continuous production of new neurons in the adult hippocampus, receives dopaminergic inputs from the neurons of the substantia nigra (SN).
  • Thus, depletion of the SN neurons during disease or in experimental settings may directly affect adult hippocampal neurogenesis.

  • Hazardous Substances Data Bank. 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE .
  • Hazardous Substances Data Bank. DOPAMINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • [Cites] Mol Cell Neurosci. 2003 Jul;23(3):373-82 [12837622.001]
  • [Cites] J Comp Neurol. 2004 Oct 25;478(4):359-78 [15384070.001]
  • [Cites] Lancet Neurol. 2004 May;3(5):309-16 [15099546.001]
  • [Cites] Nat Neurosci. 2004 Jul;7(7):726-35 [15195095.001]
  • [Cites] Eur J Neurosci. 2004 Jul;20(2):575-9 [15233767.001]
  • [Cites] Trends Neurosci. 2004 Aug;27(8):447-52 [15271491.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13363-7 [15340159.001]
  • [Cites] Brain Res Bull. 1982 Jul-Dec;9(1-6):321-53 [6816390.001]
  • [Cites] Neurosci Lett. 1980 Jun;18(2):125-31 [7052484.001]
  • [Cites] Neuroscience. 1985 Apr;14(4):1039-52 [2860616.001]
  • [Cites] Histochem J. 1992 Mar;24(3):121-31 [1349881.001]
  • [Cites] Brain Res. 1994 Dec 30;668(1-2):71-9 [7704620.001]
  • [Cites] Prog Neuropsychopharmacol Biol Psychiatry. 1997 Jan;21(1):1-22 [9075256.001]
  • [Cites] J Neural Transm (Vienna). 1998;105(2-3):317-27 [9660110.001]
  • [Cites] N Engl J Med. 2004 Dec 9;351(24):2498-508 [15590952.001]
  • [Cites] Neuroscience. 2005;132(3):777-88 [15837138.001]
  • [Cites] J Neurosci. 2005 Jun 15;25(24):5815-23 [15958748.001]
  • [Cites] Annu Rev Neurosci. 2005;28:223-50 [16022595.001]
  • [Cites] J Clin Neurosci. 2005 Sep;12(7):739-43 [16026985.001]
  • [Cites] Adv Neurol. 2005;96:26-41 [16383210.001]
  • [Cites] Ann Neurol. 2006 Jan;59(1):81-91 [16261566.001]
  • [Cites] NeuroRx. 2005 Jul;2(3):484-94 [16389312.001]
  • [Cites] Neurobiol Dis. 2006 Feb;21(2):324-32 [16137890.001]
  • [Cites] J Neurosci. 2006 Feb 22;26(8):2321-5 [16495459.001]
  • [Cites] Nat Rev Neurosci. 2006 Mar;7(3):179-93 [16495940.001]
  • [Cites] Hippocampus. 2006;16(3):239-49 [16425236.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 May 23;103(21):8233-8 [16702546.001]
  • [Cites] Glia. 2006 Dec;54(8):805-14 [16958090.001]
  • [Cites] Nat Rev Drug Discov. 2006 Oct;5(10):845-54 [17016425.001]
  • [Cites] J Neurochem. 2007 Feb;100(3):587-95 [17101030.001]
  • [Cites] Nat Protoc. 2007;2(1):141-51 [17401348.001]
  • [Cites] Prog Brain Res. 2007;163:697-722 [17765746.001]
  • [Cites] Methods Cell Biol. 2008;85:243-72 [18155466.001]
  • [Cites] Cell. 2008 Feb 22;132(4):645-60 [18295581.001]
  • [Cites] J Neurosci. 2008 Feb 27;28(9):2231-41 [18305256.001]
  • [Cites] Neuroscience. 2008 May 15;153(3):664-70 [18407421.001]
  • [Cites] J Neurosci. 2008 Nov 26;28(48):12901-12 [19036984.001]
  • [Cites] Lancet Neurol. 2009 May;8(5):464-74 [19375664.001]
  • [Cites] Neurology. 2009 May 26;72(21 Suppl 4):S1-136 [19470958.001]
  • [Cites] Proc Natl Acad Sci U S A. 2009 May 26;106(21):8754-9 [19433789.001]
  • [Cites] Exp Neurol. 2009 Oct;219(2):516-23 [19615997.001]
  • [Cites] J Comp Neurol. 2004 Feb 9;469(3):311-24 [14730584.001]
  • (PMID = 20079351.001).
  • [ISSN] 1090-2430
  • [Journal-full-title] Experimental neurology
  • [ISO-abbreviation] Exp. Neurol.
  • [Language] ENG
  • [Grant] United States / NIMH NIH HHS / MH / MH081258-02; United States / NIMH NIH HHS / MH / R21 MH081258; United States / NIMH NIH HHS / MH / R21 MH081258-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dopamine Agents; 0 / Homeodomain Proteins; 0 / Neural Cell Adhesion Molecule L1; 0 / Proliferating Cell Nuclear Antigen; 0 / Sialic Acids; 0 / Tumor Suppressor Proteins; 0 / polysialyl neural cell adhesion molecule; 0 / prospero-related homeobox 1 protein; 46627O600J / Levodopa; 9P21XSP91P / 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; EC 1.14.16.2 / Tyrosine 3-Monooxygenase; G34N38R2N1 / Bromodeoxyuridine; VTD58H1Z2X / Dopamine
  • [Other-IDs] NLM/ NIHMS170640; NLM/ PMC3042396
  •  go-up   go-down


45. Kim JH, Kim SS, Suk SI: Incidence of proximal adjacent failure in adult lumbar deformity correction based on proximal fusion level. Asian Spine J; 2007 Jun;1(1):19-26

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence of proximal adjacent failure in adult lumbar deformity correction based on proximal fusion level.
  • PURPOSE: To review the results and proximal adjacent problems of long fusion (more than 4 levels) according to the level of proximal fusion (L2~T9) in adult lumbar deformity using pedicle screw fixation.
  • OVERVIEW OF LITERATURE: There are few written reports concerning proximal adjacent segmental failure according to the level of proximal fusion in adult lumbar deformity.
  • METHODS: The radiographs and clinical records of thirty-five patients (30 females, 5 males) of adult lumbar deformity with more than 2-year follow-up after surgery were analyzed.
  • All patients were divided into three groups according to the level of proximal fusion: Group 1 (n=14) fusion up to L1 or L2; Group 2 (n=14) fusion up to T11 or T12; and Group 3 (n=7) fusion up to T9 or T10.
  • CONCLUSIONS: Fusion up to throacolumbar junction (L2~T11) in surgical treatment of adult lumbar deformity had more proximal adjacent problems with poorer results.
  • Fusion higher than T10 is recommended for adult lumbar deformity.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Spine (Phila Pa 1976). 2003 Sep 15;28(18):2164-9; discussion 2169 [14501930.001]
  • [Cites] Spine (Phila Pa 1976). 2002 Apr 1;27(7):776-86 [11923673.001]
  • [Cites] Spine (Phila Pa 1976). 1989 Dec;14(12):1391-7 [2533406.001]
  • [Cites] Spine (Phila Pa 1976). 1990 Jul;15(7):650-3 [2218710.001]
  • [Cites] Spine (Phila Pa 1976). 2006 Feb 1;31(3):303-8 [16449903.001]
  • [Cites] Spine (Phila Pa 1976). 1986 Oct;11(8):824-9 [3027899.001]
  • [Cites] Orthop Clin North Am. 1988 Apr;19(2):347-51 [3282202.001]
  • [Cites] Clin Orthop Relat Res. 1988 Feb;227:10-23 [3338200.001]
  • [Cites] J Bone Joint Surg Am. 1972 Apr;54(3):492-510 [5055149.001]
  • [Cites] J Bone Joint Surg Am. 1981 Feb;63(2):268-87 [6450768.001]
  • [Cites] Spine (Phila Pa 1976). 1981 May-Jun;6(3):268-73 [6455747.001]
  • [Cites] Spine (Phila Pa 1976). 1983 Jul-Aug;8(5):489-500 [6648699.001]
  • [Cites] J Bone Joint Surg Am. 1995 Apr;77(4):513-23 [7713967.001]
  • [Cites] Spine (Phila Pa 1976). 1994 Jan 15;19(2):123-8 [8153817.001]
  • [Cites] Orthopade. 1993 Aug;22(4):232-42 [8414480.001]
  • [Cites] J South Orthop Assoc. 1996 Fall;5(3):221-8 [8884710.001]
  • [Cites] Spine (Phila Pa 1976). 1997 Oct 15;22(20):2452-7 [9355229.001]
  • [Cites] Spine (Phila Pa 1976). 1999 Aug 15;24(16):1712-20 [10472106.001]
  • [Cites] Spine (Phila Pa 1976). 2001 May 1;26(9):E182-92 [11337635.001]
  • [Cites] J Neurosurg Spine. 2004 Jul;1(1):1-8 [15291013.001]
  • (PMID = 20411148.001).
  • [ISSN] 1976-7846
  • [Journal-full-title] Asian spine journal
  • [ISO-abbreviation] Asian Spine J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2857492
  • [Keywords] NOTNLM ; Adjacent segmental failure / Adult lumbar deformity / Proximal adjacent problem / Proximal fusion level
  •  go-up   go-down


46. Olsson SE, Villa LL, Costa RL, Petta CA, Andrade RP, Malm C, Iversen OE, Høye J, Steinwall M, Riis-Johannessen G, Andersson-Ellstrom A, Elfgren K, von Krogh G, Lehtinen M, Paavonen J, Tamms GM, Giacoletti K, Lupinacci L, Esser MT, Vuocolo SC, Saah AJ, Barr E: Induction of immune memory following administration of a prophylactic quadrivalent human papillomavirus (HPV) types 6/11/16/18 L1 virus-like particle (VLP) vaccine. Vaccine; 2007 Jun 21;25(26):4931-9
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Induction of immune memory following administration of a prophylactic quadrivalent human papillomavirus (HPV) types 6/11/16/18 L1 virus-like particle (VLP) vaccine.
  • [MeSH-minor] Adolescent. Adult. Antibodies, Viral / blood. Dose-Response Relationship, Drug. Double-Blind Method. Follow-Up Studies. Human papillomavirus 11 / immunology. Human papillomavirus 16 / immunology. Human papillomavirus 18 / immunology. Humans. Immunization Schedule

  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17499406.001).
  • [ISSN] 0264-410X
  • [Journal-full-title] Vaccine
  • [ISO-abbreviation] Vaccine
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies, Viral; 0 / Papillomavirus Vaccines
  •  go-up   go-down


47. Barr E, Gause CK, Bautista OM, Railkar RA, Lupinacci LC, Insinga RP, Sings HL, Haupt RM: Impact of a prophylactic quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like particle vaccine in a sexually active population of North American women. Am J Obstet Gynecol; 2008 Mar;198(3):261.e1-11
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of a prophylactic quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like particle vaccine in a sexually active population of North American women.
  • [MeSH-minor] Adolescent. Adult. Canada. Female. Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18. Humans. Puerto Rico. Sexual Behavior. United States

  • MedlinePlus Health Information. consumer health - HPV.
  • MedlinePlus Health Information. consumer health - Warts.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18313445.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; 0 / Papillomavirus Vaccines
  •  go-up   go-down


48. Okamoto K, Doita M, Yoshikawa M, Manabe M, Sha N, Yoshiya S: Lumbar chance fracture in an adult snowboarder: unusual mechanism of a chance fracture. Spine (Phila Pa 1976); 2005 Jan 15;30(2):E56-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lumbar chance fracture in an adult snowboarder: unusual mechanism of a chance fracture.
  • STUDY DESIGN: A case of a Chance fracture in an adult snowboarder following a fall is presented.
  • To the authors' knowledge, this is the first reported case of a lumbar Chance fracture in an adult snowboarder.
  • METHODS: A 25-year-old snowboarder sustained an L1 Chance fracture following a fall backward.
  • A Chance-type fracture can be seen in an adult snowboarder, when acute hyperflexion of the spine occurs following a fall backward.
  • [MeSH-minor] Accidental Falls. Adult. Casts, Surgical. Humans. Immobilization. Male. Tomography, X-Ray Computed. Treatment Outcome


49. Wheeler CM, Kjaer SK, Sigurdsson K, Iversen OE, Hernandez-Avila M, Perez G, Brown DR, Koutsky LA, Tay EH, García P, Ault KA, Garland SM, Leodolter S, Olsson SE, Tang GW, Ferris DG, Paavonen J, Steben M, Bosch FX, Dillner J, Joura EA, Kurman RJ, Majewski S, Muñoz N, Myers ER, Villa LL, Taddeo FJ, Roberts C, Tadesse A, Bryan J, Lupinacci LC, Giacoletti KE, James M, Vuocolo S, Hesley TM, Barr E: The impact of quadrivalent human papillomavirus (HPV; types 6, 11, 16, and 18) L1 virus-like particle vaccine on infection and disease due to oncogenic nonvaccine HPV types in sexually active women aged 16-26 years. J Infect Dis; 2009 Apr 1;199(7):936-44
International Agency for Research on Cancer - Screening Group. diagnostics - Planning and Implementing Cervical Cancer Prevention and Control Programs: A Manual for Managers .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The impact of quadrivalent human papillomavirus (HPV; types 6, 11, 16, and 18) L1 virus-like particle vaccine on infection and disease due to oncogenic nonvaccine HPV types in sexually active women aged 16-26 years.
  • [MeSH-minor] Adenocarcinoma / prevention & control. Adenocarcinoma / virology. Adolescent. Adult. Cervical Intraepithelial Neoplasia / prevention & control. Cervical Intraepithelial Neoplasia / virology. Female. Humans. Young Adult

  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • MedlinePlus Health Information. consumer health - HPV.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Infect Dis. 2009 Apr 1;199(7):919-22 [19236278.001]
  • (PMID = 19236277.001).
  • [ISSN] 0022-1899
  • [Journal-full-title] The Journal of infectious diseases
  • [ISO-abbreviation] J. Infect. Dis.
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT00092482/ NCT00092521/ NCT00092534
  • [Publication-type] Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Papillomavirus Vaccines
  •  go-up   go-down


50. Jung SY, Park YB, Ha YJ, Lee KH, Lee SK: Serum calprotectin as a marker for disease activity and severity in adult-onset Still's disease. J Rheumatol; 2010 May;37(5):1029-34
Genetic Alliance. consumer health - Still's disease adult onset.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Serum calprotectin as a marker for disease activity and severity in adult-onset Still's disease.
  • Our objective was to measure serum calprotectin concentrations in patients with adult-onset Still's disease (AOSD) and to correlate serum calprotectin with the activity and severity of AOSD.
  • [MeSH-major] Leukocyte L1 Antigen Complex / blood. Severity of Illness Index. Still's Disease, Adult-Onset / blood
  • [MeSH-minor] Adult. Biomarkers / blood. Enzyme-Linked Immunosorbent Assay. Female. Health Status. Humans. Male. Middle Aged. Statistics, Nonparametric

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20231196.001).
  • [ISSN] 0315-162X
  • [Journal-full-title] The Journal of rheumatology
  • [ISO-abbreviation] J. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Leukocyte L1 Antigen Complex
  •  go-up   go-down


51. Ault KA, Future II Study Group: Effect of prophylactic human papillomavirus L1 virus-like-particle vaccine on risk of cervical intraepithelial neoplasia grade 2, grade 3, and adenocarcinoma in situ: a combined analysis of four randomised clinical trials. Lancet; 2007 Jun 2;369(9576):1861-8
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of prophylactic human papillomavirus L1 virus-like-particle vaccine on risk of cervical intraepithelial neoplasia grade 2, grade 3, and adenocarcinoma in situ: a combined analysis of four randomised clinical trials.
  • [MeSH-minor] Adolescent. Adult. Double-Blind Method. Endpoint Determination. Female. Follow-Up Studies. Human papillomavirus 16 / drug effects. Human papillomavirus 16 / pathogenicity. Human papillomavirus 18 / drug effects. Human papillomavirus 18 / pathogenicity. Humans. Multicenter Studies as Topic. Randomized Controlled Trials as Topic

  • Genetic Alliance. consumer health - Cervical Intraepithelial Neoplasia.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Lancet. 2007 Sep 22;370(9592):1031; author reply 1032-3 [17889237.001]
  • [CommentIn] Lancet. 2007 Jun 2;369(9576):1837-9 [17544748.001]
  • [CommentIn] Evid Based Med. 2007 Dec;12(6):168 [18063728.001]
  • [CommentIn] Lancet. 2007 Sep 22;370(9592):1031-2; author reply 1032-3 [17889236.001]
  • (PMID = 17544766.001).
  • [ISSN] 1474-547X
  • [Journal-full-title] Lancet (London, England)
  • [ISO-abbreviation] Lancet
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT00092521/ NCT00092534/ NCT00365378/ NCT00365716
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Papillomavirus Vaccines
  •  go-up   go-down


52. Brown DR, Kjaer SK, Sigurdsson K, Iversen OE, Hernandez-Avila M, Wheeler CM, Perez G, Koutsky LA, Tay EH, Garcia P, Ault KA, Garland SM, Leodolter S, Olsson SE, Tang GW, Ferris DG, Paavonen J, Steben M, Bosch FX, Dillner J, Joura EA, Kurman RJ, Majewski S, Muñoz N, Myers ER, Villa LL, Taddeo FJ, Roberts C, Tadesse A, Bryan J, Lupinacci LC, Giacoletti KE, Sings HL, James M, Hesley TM, Barr E: The impact of quadrivalent human papillomavirus (HPV; types 6, 11, 16, and 18) L1 virus-like particle vaccine on infection and disease due to oncogenic nonvaccine HPV types in generally HPV-naive women aged 16-26 years. J Infect Dis; 2009 Apr 1;199(7):926-35
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The impact of quadrivalent human papillomavirus (HPV; types 6, 11, 16, and 18) L1 virus-like particle vaccine on infection and disease due to oncogenic nonvaccine HPV types in generally HPV-naive women aged 16-26 years.
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Uterine Cervical Neoplasms / prevention & control. Uterine Cervical Neoplasms / virology. Young Adult

  • MedlinePlus Health Information. consumer health - HPV.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Infect Dis. 2009 Apr 1;199(7):919-22 [19236278.001]
  • (PMID = 19236279.001).
  • [ISSN] 0022-1899
  • [Journal-full-title] The Journal of infectious diseases
  • [ISO-abbreviation] J. Infect. Dis.
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT00092482/ NCT00092521/ NCT00092534
  • [Publication-type] Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Papillomavirus Vaccines
  •  go-up   go-down


53. Horinouchi K, Nakamura Y, Yamanaka H, Watabe T, Shiosaka S: Distribution of L1cam mRNA in the adult mouse brain: In situ hybridization and Northern blot analyses. J Comp Neurol; 2005 Feb 21;482(4):386-404

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distribution of L1cam mRNA in the adult mouse brain: In situ hybridization and Northern blot analyses.
  • Previous immunohistochemical analysis revealed a wide distribution of L1cam-positive neural and nonneural structures in adult mouse brain.
  • L1cam mRNA was distributed widely from the olfactory bulb to the upper cervical cord with an uneven localization pattern in adult brain.
  • [MeSH-major] Brain / metabolism. Neural Cell Adhesion Molecule L1 / genetics. Neurons / metabolism. RNA, Messenger / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 15669056.001).
  • [ISSN] 0021-9967
  • [Journal-full-title] The Journal of comparative neurology
  • [ISO-abbreviation] J. Comp. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecule L1; 0 / RNA, Messenger
  •  go-up   go-down


54. Hong JY, Suh SW, Modi HN, Hur CY, Song HR, Park JH: Reliability analysis for radiographic measures of lumbar lordosis in adult scoliosis: a case-control study comparing 6 methods. Eur Spine J; 2010 Sep;19(9):1551-7
MedlinePlus Health Information. consumer health - Scoliosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reliability analysis for radiographic measures of lumbar lordosis in adult scoliosis: a case-control study comparing 6 methods.
  • In adult scoliosis patients, the measurement is difficult due to degenerative changes in the vertebral endplate as well as the coronal and sagittal deformity.
  • We did the observational study with three examiners to determine the reliability of six methods for measuring the global lumbar lordosis in adult scoliosis patients.
  • The radiographs were divided into normal (Cobb < 10 degrees ), low-grade (Cobb 10 degrees -19 degrees ), high-grade (Cobb >or= 20 degrees ) group to determine the reliability of Cobb L1-S1, Cobb L1-L5, centroid, posterior tangent L1-S1, posterior tangent L1-L5 and TRALL method in adult scoliosis.
  • In Cobb L1-S1, centroid and posterior tangent L1-S1 methods, the ICCs were relatively lower in the high-grade scoliosis group (>or=0.60).
  • However, in the Cobb L1-L5 and posterior tangent L1-L5 method, the ICCs were >or=0.86 in all groups.
  • In addition, in the Cobb L1-L5 and posterior tangent L1-L5 method, the MAD was <or=3.63 degrees .
  • We concluded that the Cobb L1-L5 and the posterior tangent L1-L5 methods are reliable methods for measuring the global lumbar lordosis in adult scoliosis.

  • Genetic Alliance. consumer health - Lordosis.
  • Genetic Alliance. consumer health - Scoliosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Spine (Phila Pa 1976). 2000 Mar 1;25(5):575-86 [10749634.001]
  • [Cites] Spine (Phila Pa 1976). 2009 Mar 15;34(6):603-8 [19282739.001]
  • [Cites] J Clin Densitom. 2000 Fall;3(3):281-90 [11090235.001]
  • [Cites] Spine (Phila Pa 1976). 2001 Jun 1;26(11):E227-34 [11389406.001]
  • [Cites] Spine (Phila Pa 1976). 2001 Jun 1;26(11):E235-42 [11389407.001]
  • [Cites] Spine (Phila Pa 1976). 2002 Feb 15;27(4):387-92 [11840105.001]
  • [Cites] Spine (Phila Pa 1976). 2002 Oct 15;27(20):2268-73 [12394905.001]
  • [Cites] Eur Spine J. 2002 Dec;11(6):535-42 [12522710.001]
  • [Cites] J Bone Joint Surg Br. 1985 Aug;67(4):625-9 [4030863.001]
  • [Cites] Spine (Phila Pa 1976). 1989 Jul;14(7):717-21 [2772721.001]
  • [Cites] J Bone Joint Surg Am. 1990 Mar;72(3):320-7 [2312527.001]
  • [Cites] J Bone Joint Surg Am. 1990 Mar;72(3):328-33 [2312528.001]
  • [Cites] Stat Methods Med Res. 1992;1(2):123-57 [1341655.001]
  • [Cites] Spine (Phila Pa 1976). 1996 Jul 1;21(13):1530-5; discussion 1535-6 [8817780.001]
  • [Cites] Spine (Phila Pa 1976). 1997 Apr 1;22(7):734-43 [9106313.001]
  • [Cites] J Spinal Disord. 1997 Oct;10(5):380-6 [9355053.001]
  • [Cites] Spine (Phila Pa 1976). 1998 Jan 1;23(1):74-9; discussion 79-80 [9460156.001]
  • [Cites] J Manipulative Physiol Ther. 1998 Sep;21(7):460-7 [9777546.001]
  • [Cites] Spine (Phila Pa 1976). 1999 Sep 1;24(17):1786-90 [10488508.001]
  • [Cites] J Bone Joint Surg Br. 1965 Aug;47:552-5 [14341078.001]
  • [Cites] Spine (Phila Pa 1976). 2005 Mar 15;30(6):682-8 [15770185.001]
  • [Cites] Psychol Bull. 1979 Mar;86(2):420-8 [18839484.001]
  • [Cites] Spine (Phila Pa 1976). 2000 Aug 15;25(16):2072-8 [10954638.001]
  • (PMID = 20437183.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2989293
  •  go-up   go-down


55. Liu TT, Bannatyne BA, Maxwell DJ: Organization and neurochemical properties of intersegmental interneurons in the lumbar enlargement of the adult rat. Neuroscience; 2010 Dec 1;171(2):461-84
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Organization and neurochemical properties of intersegmental interneurons in the lumbar enlargement of the adult rat.
  • Intersegmental interneurons with relatively short axons perform an important role in the coordination of limb movement but surprisingly little is known about their organization and how they contribute to neuronal networks in the adult rat.
  • The b-subunit of cholera toxin was injected into L1 or L3 segments of seven rats in the vicinity of lateral or medial motor nuclei.
  • We also examined axon terminals that projected from L1/3 to the L5 contralateral lateral motor nucleus.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 IBRO. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20849930.001).
  • [ISSN] 1873-7544
  • [Journal-full-title] Neuroscience
  • [ISO-abbreviation] Neuroscience
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / R01 NS040863
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calb2 protein, rat; 0 / Calbindin 2; 0 / Calbindins; 0 / S100 Calcium Binding Protein G; EC 2.3.1.6 / Choline O-Acetyltransferase
  •  go-up   go-down


56. Franceschini I, Desroziers E, Caraty A, Duittoz A: The intimate relationship of gonadotropin-releasing hormone neurons with the polysialylated neural cell adhesion molecule revisited across development and adult plasticity. Eur J Neurosci; 2010 Dec;32(12):2031-41
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The intimate relationship of gonadotropin-releasing hormone neurons with the polysialylated neural cell adhesion molecule revisited across development and adult plasticity.
  • In this review, we will focus on the intimate relationship of developing and adult GnRH neurons with the polysialylated form of neural cell adhesion molecule (PSA-NCAM), a major molecular actor in the morphogenesis and adult plasticity of the nervous system.
  • In the adult, we will review the relationships between PSA-NCAM and GnRH neurons across various physiological states, and open the discussion to the use of new model systems that can help to unravel the function and mechanism of action of PSA-NCAM on GnRH neuronal network activity and GnRH release.
  • [MeSH-major] Gonadotropin-Releasing Hormone / metabolism. Neural Cell Adhesion Molecule L1 / metabolism. Neuronal Plasticity / physiology. Neurons / physiology. Sialic Acids / metabolism

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2010 The Authors. European Journal of Neuroscience © 2010 Federation of European Neuroscience Societies and Blackwell Publishing Ltd.
  • (PMID = 21143658.001).
  • [ISSN] 1460-9568
  • [Journal-full-title] The European journal of neuroscience
  • [ISO-abbreviation] Eur. J. Neurosci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecule L1; 0 / Sialic Acids; 0 / polysialyl neural cell adhesion molecule; 33515-09-2 / Gonadotropin-Releasing Hormone
  •  go-up   go-down


57. Block SL, Brown DR, Chatterjee A, Gold MA, Sings HL, Meibohm A, Dana A, Haupt RM, Barr E, Tamms GM, Zhou H, Reisinger KS: Clinical trial and post-licensure safety profile of a prophylactic human papillomavirus (types 6, 11, 16, and 18) l1 virus-like particle vaccine. Pediatr Infect Dis J; 2010 Feb;29(2):95-101
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical trial and post-licensure safety profile of a prophylactic human papillomavirus (types 6, 11, 16, and 18) l1 virus-like particle vaccine.
  • [MeSH-minor] Adolescent. Adult. Child. Drug-Related Side Effects and Adverse Reactions. Female. Fever. Headache. Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18. Humans. Incidence. Male. Pain. Placebos / administration & dosage. Product Surveillance, Postmarketing. United States. Vaccines, Virosome / adverse effects. Vaccines, Virosome / immunology. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19952863.001).
  • [ISSN] 1532-0987
  • [Journal-full-title] The Pediatric infectious disease journal
  • [ISO-abbreviation] Pediatr. Infect. Dis. J.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Clinical Trial, Phase III; Clinical Trial, Phase IV; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; 0 / Papillomavirus Vaccines; 0 / Placebos; 0 / Vaccines, Virosome
  •  go-up   go-down


58. Amrein I, Slomianka L: A morphologically distinct granule cell type in the dentate gyrus of the red fox correlates with adult hippocampal neurogenesis. Brain Res; 2010 Apr 30;1328:12-24
Zurich Open Access Repository and Archive. Full text from .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A morphologically distinct granule cell type in the dentate gyrus of the red fox correlates with adult hippocampal neurogenesis.
  • Wild red foxes, proverbially cunning carnivores, are investigated for adult hippocampal neurogenesis and morphological characteristics of the dentate gyrus.
  • Adult red foxes harbor almost 15-times more young, doublecortin-positive neurons in their dentate gyrus than domesticated dogs.
  • In summary, we report a morphologically distinct granule cell type which correlates with adult hippocampal neurogenesis in the fox.
  • [MeSH-minor] Adaptation, Physiological / physiology. Aging / physiology. Animals. Basic Helix-Loop-Helix Transcription Factors / metabolism. Biomarkers / metabolism. Cell Count. Cell Differentiation / physiology. Cell Proliferation. Cell Shape / physiology. Dynorphins / metabolism. Endorphins / metabolism. Female. GAP-43 Protein / metabolism. Immunohistochemistry. Intelligence / physiology. Ki-67 Antigen / metabolism. Learning / physiology. Male. Microtubule-Associated Proteins / metabolism. Nerve Tissue Proteins / metabolism. Neural Cell Adhesion Molecule L1 / metabolism. Neuronal Plasticity / physiology. Neuropeptides / metabolism. Parvalbumins / metabolism. Proto-Oncogene Proteins c-fos / metabolism. Receptors, Glutamate / metabolism. Sex Characteristics. Sialic Acids / metabolism. Species Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20206610.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / Biomarkers; 0 / Endorphins; 0 / GAP-43 Protein; 0 / Ki-67 Antigen; 0 / Microtubule-Associated Proteins; 0 / Nerve Tissue Proteins; 0 / Neural Cell Adhesion Molecule L1; 0 / Neuropeptides; 0 / Parvalbumins; 0 / Proto-Oncogene Proteins c-fos; 0 / Receptors, Glutamate; 0 / Sialic Acids; 0 / doublecortin protein; 0 / polysialyl neural cell adhesion molecule; 169238-82-8 / NeuroD protein; 74913-18-1 / Dynorphins; 83335-41-5 / rimorphin
  •  go-up   go-down


59. Quartu M, Serra MP, Boi M, Melis T, Ambu R, Del Fiacco M: Brain-derived neurotrophic factor (BDNF) and polysialylated-neural cell adhesion molecule (PSA-NCAM): codistribution in the human brainstem precerebellar nuclei from prenatal to adult age. Brain Res; 2010 Dec 2;1363:49-62
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brain-derived neurotrophic factor (BDNF) and polysialylated-neural cell adhesion molecule (PSA-NCAM): codistribution in the human brainstem precerebellar nuclei from prenatal to adult age.
  • Occurrence and distribution of the neurotrophin brain-derived neurotrophic factor (BDNF) and polysialylated-neural cell adhesion molecule (PSA-NCAM), a neuroplasticity marker known to modulate BDNF signalling, were examined by immunohistochemistry in the human brainstem precerebellar nuclei at prenatal, perinatal and adult age.
  • With few exceptions, for both substances the distribution pattern detected at prenatal age persisted later on, though the immunoreactivity appeared often higher in pre- and full-term newborns than in adult specimens.
  • [MeSH-major] Aging / physiology. Brain Stem / metabolism. Brain-Derived Neurotrophic Factor / metabolism. Neural Cell Adhesion Molecule L1 / metabolism. Neuronal Plasticity / physiology. Sialic Acids / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Animals. Blotting, Western. Child. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neural Pathways / cytology. Neural Pathways / metabolism. Rats. Young Adult

  • MedlinePlus Health Information. consumer health - Seniors' Health.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20932956.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Brain-Derived Neurotrophic Factor; 0 / Neural Cell Adhesion Molecule L1; 0 / Sialic Acids; 0 / polysialyl neural cell adhesion molecule
  •  go-up   go-down


60. Higuchi T, Toyama D, Hirota Y, Isoyama K, Mori H, Niikura H, Yamada K, Omine M: Disseminated intravascular coagulation complicating acute lymphoblastic leukemia: a study of childhood and adult cases. Leuk Lymphoma; 2005 Aug;46(8):1169-76
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Disseminated intravascular coagulation complicating acute lymphoblastic leukemia: a study of childhood and adult cases.
  • A high incidence of disseminated intravascular coagulation (DIC) in adult patients with acute lymphoblastic leukemia (ALL) is reported.
  • However, studies comprising both childhood and adult patients are sparse and the clinical relevance of DIC in ALL patients has been a conflicting issue.
  • Coagulation profiles at presentation and within seven days after starting remission-induction therapy of 44 childhood and 51 adult ALL patients were studied.
  • At presentation, two childhood (5%) and 11 adult (22%) patients had DIC (p<0.05).
  • After starting therapy, four of 27 childhood (15%) and 14 of 33 adult (42%) patients screened for coagulopathy developed DIC (p<0.05).
  • In the adult cases, DIC was more frequently complicated with FAB subtype L2 than L1 (p<0.05).
  • In the adult patients, two patients with DIC had WHO grade 3 hemorrhage and the other hemorrhagic complications were minor hemorrhages.
  • While milder induction therapies starting with corticosteroid given for childhood cases should be taken into consideration when comparing the incidences of DIC after therapy, the findings indicated that childhood and adult ALL may differ in the procoagulant characteristics.
  • Morphological distinction between L1 and L2 appears to have relevance in the procoagulant activity in adult ALL.
  • [MeSH-major] Disseminated Intravascular Coagulation / complications. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Follow-Up Studies. Hemorrhage / complications. Humans. Infant. Male. Middle Aged. Remission Induction / methods. Retrospective Studies

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16085558.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  •  go-up   go-down


61. Schwab F, el-Fegoun AB, Gamez L, Goodman H, Farcy JP: A lumbar classification of scoliosis in the adult patient: preliminary approach. Spine (Phila Pa 1976); 2005 Jul 15;30(14):1670-3
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A lumbar classification of scoliosis in the adult patient: preliminary approach.
  • OBJECTIVE: To create a preliminary approach to a clinically important classification of scoliosis in adult patients.
  • METHODS: A total of 98 adult patients with scoliosis with a 2-year minimum treatment/follow-up were included.
  • Patients were classified into one of 3 types of deformity based on the degree of lordosis (L1-S1) and frontal plane endplate obliquity of L3 on standing radiographs: type I = lordosis > 55 degrees, L3 obliquity < 15 degrees; type II = lordosis 35 degrees-55 degrees, L3 obliquity 15 degrees-25 degrees; and type III = lordosis < 35 degrees, L3 obliquity > 25 degrees.
  • Significant correlation between endplate obliquity L3, L1-S1 lordosis and VAS was noted (P < 0.05).
  • CONCLUSIONS: A simple classification of adult scoliosis was developed based on frontal and sagittal plane standing radiographs.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disability Evaluation. Follow-Up Studies. Humans. Lordosis / classification. Lordosis / radiography. Lordosis / therapy. Low Back Pain / classification. Low Back Pain / radiography. Low Back Pain / therapy. Middle Aged. Retrospective Studies. Treatment Failure

  • Genetic Alliance. consumer health - Scoliosis.
  • MedlinePlus Health Information. consumer health - Scoliosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16025039.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


62. Bae JS, Lee SH, Kim JS, Jung B, Choi G: Adjacent segment degeneration after lumbar interbody fusion with percutaneous pedicle screw fixation for adult low-grade isthmic spondylolisthesis: minimum 3 years of follow-up. Neurosurgery; 2010 Dec;67(6):1600-7; discussion 1607-8
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adjacent segment degeneration after lumbar interbody fusion with percutaneous pedicle screw fixation for adult low-grade isthmic spondylolisthesis: minimum 3 years of follow-up.
  • OBJECTIVE: To investigate ASD after instrumented LIF performed at a single level and only for the homogeneous disease of adult low-grade isthmic spondylolisthesis.
  • METHODS: A total of 128 patients who had undergone LIF for the treatment of adult low-grade isthmic spondylolisthesis involving the lower lumbar spine at our institution between February 2001 and December 2004 were retrospectively reviewed by chart review and telephone survey.
  • Clinical and radiological data related to segmental lordosis (SL), whole lumbar lordosis, sacral slope, pelvic tilt, pelvic incidence, and L1 axis S1 distance were analyzed to identify significant risk factors for ASD.
  • Postoperative SL, preoperative SL, whole lumbar lordosis, and L1 axis S1 distance were significant risk factors for ASD.
  • CONCLUSION: ASD may occur at a relatively lower incidence in adult low-grade isthmic spondylolisthesis compared with other degenerative lumbar spinal diseases.
  • [MeSH-minor] Adult. Aged. Chi-Square Distribution. Female. Humans. Longitudinal Studies. Lumbar Vertebrae / pathology. Lumbar Vertebrae / radiography. Lumbar Vertebrae / surgery. Male. Middle Aged. Retrospective Studies. Statistics, Nonparametric. Tomography, X-Ray Computed / methods. Treatment Outcome. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21107190.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


63. Quartu M, Serra MP, Boi M, Ibba V, Melis T, Del Fiacco M: Polysialylated-neural cell adhesion molecule (PSA-NCAM) in the human trigeminal ganglion and brainstem at prenatal and adult ages. BMC Neurosci; 2008;9:108
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Polysialylated-neural cell adhesion molecule (PSA-NCAM) in the human trigeminal ganglion and brainstem at prenatal and adult ages.
  • With the aim of providing information relevant to the potential for dynamic changes of specific neuronal populations in man, this study analyses the immunohistochemical occurrence of PSA-NCAM in the human trigeminal ganglion (TG) and brainstem neuronal populations at prenatal and adult age.
  • In the TG, PSA-NCAM is localized to neuronal perikarya, nerve fibres, pericellular networks, and satellite and Schwann cells; further, cytoplasmic perikaryal staining and positive pericellular fibre networks are detectable with higher frequency in adult than in newborn tissue.
  • In the adult tissue, positive neurons are mostly small- and medium-sized, and amount to about 6% of the total ganglionic population.
  • In specimens of different age, the distribution pattern remains fairly steady, whereas the density of immunoreactive structures and the staining intensity may change and are usually higher in newborn than in adult specimens.
  • [MeSH-major] Aging / metabolism. Brain Stem / embryology. Brain Stem / metabolism. Neural Cell Adhesion Molecule L1 / metabolism. Neurons / metabolism. Sialic Acids / metabolism. Trigeminal Ganglion / embryology. Trigeminal Ganglion / metabolism
  • [MeSH-minor] Adult. Gene Expression Regulation, Developmental / physiology. Humans. Tissue Distribution

  • MedlinePlus Health Information. consumer health - Seniors' Health.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Biol Chem. 1951 Nov;193(1):265-75 [14907713.001]
  • [Cites] Neuroscience. 1999;93(1):293-305 [10430493.001]
  • [Cites] J Neurosci. 2005 Feb 23;25(8):2081-91 [15728848.001]
  • [Cites] Brain Res Mol Brain Res. 2005 Jun 13;137(1-2):223-34 [15950781.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11516-20 [16055555.001]
  • [Cites] Neuroscience. 2006;138(4):1215-23 [16431029.001]
  • [Cites] Auton Neurosci. 2006 Jun 30;126-127:50-8 [16697711.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16989-94 [17075041.001]
  • [Cites] Prog Neurobiol. 2006 Oct;80(3):129-64 [17029752.001]
  • [Cites] Neurobiol Dis. 2007 May;26(2):385-95 [17336079.001]
  • [Cites] J Chem Neuroanat. 2007 Jul;33(4):202-9 [17467233.001]
  • [Cites] Pathol Int. 2007 Jun;57(6):358-68 [17539967.001]
  • [Cites] Brain Res Bull. 2007 Oct 19;74(5):317-28 [17845906.001]
  • [Cites] Neuroscience. 2007 Oct 26;149(2):328-37 [17900814.001]
  • [Cites] Nat Rev Neurosci. 2008 Jan;9(1):26-35 [18059411.001]
  • [Cites] Curr Opin Neurol. 2008 Feb;21(1):22-8 [18180648.001]
  • [Cites] J Neurosci. 1999 Dec 1;19(23):10228-36 [10575020.001]
  • [Cites] Int J Dev Neurosci. 2000 Apr-Jun;18(2-3):193-9 [10715574.001]
  • [Cites] J Neurobiol. 2000 Nov 15;45(3):135-41 [11074459.001]
  • [Cites] Neuroscience. 2001;103(4):1093-104 [11301216.001]
  • [Cites] Brain Res. 2001 Jun 1;902(2):288-93 [11384624.001]
  • [Cites] Eur J Neurosci. 2001 Oct;14(8):1194-202 [11703448.001]
  • [Cites] Cereb Cortex. 2002 Jun;12(6):617-24 [12003861.001]
  • [Cites] Epilepsia. 2002;43 Suppl 5:68-73 [12121298.001]
  • [Cites] Brain. 2002 Sep;125(Pt 9):1972-9 [12183343.001]
  • [Cites] Eur J Neurosci. 2003 Feb;17(4):879-86 [12603278.001]
  • [Cites] J Comp Neurol. 2003 May 26;460(2):203-11 [12687685.001]
  • [Cites] Biochimie. 2003 Jan-Feb;85(1-2):195-206 [12765789.001]
  • [Cites] Curr Med Chem. 2003 Oct;10(20):2185-96 [12871092.001]
  • [Cites] Biol Psychiatry. 2003 Sep 15;54(6):599-607 [13129654.001]
  • [Cites] J Neurotrauma. 2003 Dec;20(12):1271-92 [14748977.001]
  • [Cites] Prog Neurobiol. 2004 Jan;72(1):27-53 [15019175.001]
  • [Cites] Neuroscience. 2004;126(2):503-9 [15207367.001]
  • [Cites] Auton Neurosci. 2004 Jul 30;114(1-2):83-96 [15331048.001]
  • [Cites] Cells Tissues Organs. 2004;177(4):229-36 [15459479.001]
  • [Cites] Neuroscience. 1992 Jul;49(2):419-36 [1436474.001]
  • [Cites] Brain Res Dev Brain Res. 1993 May 21;73(1):141-5 [7685664.001]
  • [Cites] J Neurobiol. 1993 May;24(5):641-59 [7686963.001]
  • [Cites] J Neurocytol. 1993 Jun;22(6):413-24 [8345365.001]
  • [Cites] Neurosci Res. 1993 Sep;17(4):265-90 [8264989.001]
  • [Cites] Neuromuscul Disord. 1994 May;4(3):171-82 [7919966.001]
  • [Cites] Neuroreport. 1994 Nov 21;5(17):2349-52 [7533558.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2785-9 [7708724.001]
  • [Cites] J Comp Neurol. 1996 Feb 19;365(4):511-25 [8742299.001]
  • [Cites] J Neurosci Res. 1996 Jul 15;45(2):143-52 [8843031.001]
  • [Cites] Neuroscience. 1996 Oct;74(3):619-23 [8884761.001]
  • [Cites] Trends Neurosci. 1996 Oct;19(10):422-7 [8888519.001]
  • [Cites] Eur J Neurosci. 1996 Dec;8(12):2748-52 [8996824.001]
  • [Cites] Hear Res. 1997 Jan;103(1-2):123-30 [9007579.001]
  • [Cites] Hear Res. 1997 Jan;103(1-2):151-68 [9007582.001]
  • [Cites] Hear Res. 1997 Jan;103(1-2):169-91 [9007583.001]
  • [Cites] J Neurosci. 1997 Jul 15;17(14):5349-56 [9204919.001]
  • [Cites] J Auton Nerv Syst. 1997 Jul 14;65(1):25-32 [9258869.001]
  • [Cites] Eur J Neurosci. 1997 Aug;9(8):1612-24 [9283816.001]
  • [Cites] J Neurol Sci. 1997 Oct 22;151(2):127-33 [9349666.001]
  • [Cites] Exp Neurol. 1997 Oct;147(2):256-68 [9344551.001]
  • [Cites] Curr Opin Neurobiol. 1997 Oct;7(5):640-6 [9384537.001]
  • [Cites] Ann Neurol. 1998 Dec;44(6):923-34 [9851437.001]
  • [Cites] J Neurosci Res. 1999 Jan 1;55(1):54-70 [9890434.001]
  • [Cites] J Neurosci Res. 1999 Jan 1;55(1):99-106 [9890438.001]
  • [Cites] Eur J Neurosci. 1999 May;11(5):1754-64 [10215928.001]
  • [Cites] J Biol Chem. 2005 Jan 7;280(1):137-45 [15504723.001]
  • (PMID = 18990213.001).
  • [ISSN] 1471-2202
  • [Journal-full-title] BMC neuroscience
  • [ISO-abbreviation] BMC Neurosci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecule L1; 0 / Sialic Acids; 0 / polysialyl neural cell adhesion molecule
  • [Other-IDs] NLM/ PMC2612005
  •  go-up   go-down


64. Schäfer MK, Schmitz B, Diestel S: L1CAM ubiquitination facilitates its lysosomal degradation. FEBS Lett; 2010 Nov 5;584(21):4475-80
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The cell adhesion molecule L1 is implicated in several processes in the developing and adult nervous system.
  • Intracellular trafficking of L1 is important for cell migration, neurite growth and adhesion.
  • We demonstrate here that L1 is ubiquitinated at the plasma membrane and in early endosomes.
  • Mono-ubiquitination regulates L1 intracellular trafficking by enhancing its lysosomal degradation.
  • We propose that L1's ubiquitination might be an additional mechanism to control its re-appearance at the cell surface thereby influencing processes like neurite growth and cell adhesion.
  • [MeSH-major] Lysosomes / metabolism. Neural Cell Adhesion Molecule L1 / metabolism. Ubiquitination

  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20940017.001).
  • [ISSN] 1873-3468
  • [Journal-full-title] FEBS letters
  • [ISO-abbreviation] FEBS Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecule L1
  •  go-up   go-down


65. Shapiro JR, Thompson CB, Wu Y, Nunes M, Gillen C: Bone mineral density and fracture rate in response to intravenous and oral bisphosphonates in adult osteogenesis imperfecta. Calcif Tissue Int; 2010 Aug;87(2):120-9
Hazardous Substances Data Bank. Alendronic acid .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bone mineral density and fracture rate in response to intravenous and oral bisphosphonates in adult osteogenesis imperfecta.
  • For type I and grouped type III/IV patients, treatment with pamidronate showed an increasing rate in L1-L4 BMD from baseline (0.006 [P = 0.03] and 0.016 [P < 0.001] gm/cm(2)/year, respectively); oral bisphosphonate treatment showed a significant increasing rate in L1-L4 BMD (0.004 gm/cm(2)/year [P = 0.047]) for type I patients.
  • [MeSH-minor] Administration, Oral. Adult. Alendronate / therapeutic use. Cohort Studies. Female. Humans. Injections, Intravenous. Male. Retrospective Studies. Treatment Outcome

  • Genetic Alliance. consumer health - Osteogenesis imperfecta.
  • MedlinePlus Health Information. consumer health - Bone Density.
  • MedlinePlus Health Information. consumer health - Fractures.
  • MedlinePlus Health Information. consumer health - Osteogenesis Imperfecta.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20544187.001).
  • [ISSN] 1432-0827
  • [Journal-full-title] Calcified tissue international
  • [ISO-abbreviation] Calcif. Tissue Int.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Density Conservation Agents; 0 / Diphosphonates; OYY3447OMC / pamidronate; X1J18R4W8P / Alendronate
  •  go-up   go-down


66. Matsuyama K, Kobayashi S, Aoki M: Projection patterns of lamina VIII commissural neurons in the lumbar spinal cord of the adult cat: an anterograde neural tracing study. Neuroscience; 2006 Jun 19;140(1):203-18
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Projection patterns of lamina VIII commissural neurons in the lumbar spinal cord of the adult cat: an anterograde neural tracing study.
  • After 3-4 weeks, commissural axons were well labeled throughout lumbosacral segments L1-S2.

  • Hazardous Substances Data Bank. BIOTIN .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16530974.001).
  • [ISSN] 0306-4522
  • [Journal-full-title] Neuroscience
  • [ISO-abbreviation] Neuroscience
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / biotinylated dextran amine; 6SO6U10H04 / Biotin; K3R6ZDH4DU / Dextrans
  •  go-up   go-down


67. Liu B, Lu Z, Wang P, Basang Z, Rao X: Prevalence of high-risk human papillomavirus types (HPV-16, HPV-18) and their physical status in primary laryngeal squamous cell carcinoma. Neoplasma; 2010;57(6):594-600
Genetic Alliance. consumer health - Carcinoma, Squamous Cell.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • HPV genotyping was assayed prior to the integration analysis by using two PCR-based assays, including HPV-16 and-18 E7 type-specific and L1 general primers (GP5+/GP6+).
  • Using HPV L1 general primer amplification, HPV DNA was detected in 23 (27.4%) of the 84 LSCC samples.
  • When PCR products were cloned and sequenced, HPV16 were found in all 23 L1 positive samples.
  • [MeSH-minor] Adult. Aged. Capsid Proteins / genetics. DNA, Viral / analysis. DNA-Binding Proteins / genetics. Female. Humans. Male. Middle Aged. Oncogene Proteins, Viral / genetics. Papillomavirus E7 Proteins / genetics. Polymerase Chain Reaction

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20845999.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Capsid Proteins; 0 / DNA, Viral; 0 / DNA-Binding Proteins; 0 / E7 protein, Human papillomavirus type 18; 0 / L1 protein, Human papillomavirus type 16; 0 / L1 protein, Human papillomavirus type 18; 0 / Oncogene Proteins, Viral; 0 / Papillomavirus E7 Proteins; 0 / oncogene protein E7, Human papillomavirus type 16
  •  go-up   go-down


68. Steigen SE, Bjerkehagen B, Haugland HK, Nordrum IS, Løberg EM, Isaksen V, Eide TJ, Nielsen TO: Diagnostic and prognostic markers for gastrointestinal stromal tumors in Norway. Mod Pathol; 2008 Jan;21(1):46-53
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Validation of histological features as well as the prognostic value of two immunohistochemical biomarkers (p16 and L1) was assessed.
  • Expression of p16 was significantly correlated with unfavorable prognosis, whereas L1 expression was not.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cyclin-Dependent Kinase Inhibitor p16 / analysis. Gastrointestinal Stromal Tumors / diagnosis. Leukocyte L1 Antigen Complex / analysis. Proto-Oncogene Proteins c-kit / analysis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cell Nucleus / pathology. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Mitotic Index. Norway. Prognosis. Proportional Hazards Models. Reproducibility of Results. Tissue Array Analysis

  • Genetic Alliance. consumer health - Gastrointestinal Stromal Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17917670.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Leukocyte L1 Antigen Complex; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  •  go-up   go-down


69. Heubner M, Wimberger P, Kasimir-Bauer S, Otterbach F, Kimmig R, Siffert W: The AA genotype of a L1C G842A polymorphism is associated with an increased risk for ovarian cancer. Anticancer Res; 2009 Aug;29(8):3449-52
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Recent studies proposed L1CAM (L1 cell adhesion molecule) expression as a negative prognostic marker in epithelial ovarian cancer (EOC).
  • [MeSH-major] Adenocarcinoma, Clear Cell / genetics. Adenocarcinoma, Mucinous / genetics. Cystadenocarcinoma, Serous / genetics. Endometrial Neoplasms / genetics. Neural Cell Adhesion Molecule L1 / genetics. Ovarian Neoplasms / genetics. Polymorphism, Single Nucleotide / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. DNA, Neoplasm / genetics. Dinucleotide Repeats / genetics. Female. Genotype. Humans. Middle Aged. Polymerase Chain Reaction. Risk Factors. Young Adult

  • Genetic Alliance. consumer health - Ovarian cancer.
  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19661372.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Neural Cell Adhesion Molecule L1
  •  go-up   go-down


70. Montaldo C, Mastinu A, Quartuccio M, Piras V, Denotti G, Pisano E, Orrù G: Detection and genotyping of human papillomavirus DNA in samples from healthy Sardinian patients: a preliminary study. J Oral Pathol Med; 2007 Sep;36(8):482-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • For this study a sensitive seminested polymerase chain reaction (PCR) method was used to detect HPV-DNA; moreover in all positive samples, HPV genotyping was based on sequencing of the HPV genome L1 region.
  • [MeSH-minor] Adolescent. Adult. Aged. Capsid Proteins / genetics. Child. Child, Preschool. DNA Primers. DNA, Viral / genetics. Female. Genotype. Humans. Italy. Male. Middle Aged. Oncogene Proteins, Viral / genetics. Papillomavirus Infections / virology. Risk Factors. Sequence Analysis, DNA

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17686007.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Capsid Proteins; 0 / DNA Primers; 0 / DNA, Viral; 0 / L1 protein, Human papillomavirus type 16; 0 / Oncogene Proteins, Viral
  •  go-up   go-down


71. Saito T, Yamada K, Wang Y, Tanaka Y, Ohtomo K, Ishikawa K, Inagaki N: Expression of ABCA2 protein in both non-myelin-forming and myelin-forming Schwann cells in the rodent peripheral nerve. Neurosci Lett; 2007 Feb 27;414(1):35-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Here, we provide evidence for the expression of ABCA2 in the rodent sciatic nerve not only in Schwann cells, which express the Schwann cell marker S100beta and a zinc finger transcription factor Krox20 (a marker for myelin-forming Schwann cells), but also in Krox20-negative cells, which express glial fibrillary acidic protein (GFAP), a cell adhesion molecule L1, and S100beta weekly.
  • The expression of ABCA2 in Krox20+/S100beta+ Schwann cells was found initially in rat facial nerve at postnatal day (PD) 8, in half (52.4%) of the cells showing myelinization at PD 14, and in all of the cells in the adult stage.
  • [MeSH-minor] Aging / physiology. Animals. Animals, Newborn. Biomarkers / analysis. Biomarkers / metabolism. Cell Differentiation / physiology. Early Growth Response Protein 1 / metabolism. Facial Nerve / cytology. Facial Nerve / growth & development. Facial Nerve / metabolism. Glial Fibrillary Acidic Protein / metabolism. Mice. Mice, Inbred C57BL. Nerve Fibers, Myelinated / metabolism. Nerve Fibers, Myelinated / ultrastructure. Nerve Growth Factors / metabolism. Neural Cell Adhesion Molecule L1 / metabolism. Rats. Rats, Sprague-Dawley. S100 Calcium Binding Protein beta Subunit. S100 Proteins / metabolism. Sciatic Nerve / cytology. Sciatic Nerve / growth & development. Sciatic Nerve / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17240058.001).
  • [ISSN] 0304-3940
  • [Journal-full-title] Neuroscience letters
  • [ISO-abbreviation] Neurosci. Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Abca2 protein, mouse; 0 / Biomarkers; 0 / Early Growth Response Protein 1; 0 / Egr1 protein, mouse; 0 / Glial Fibrillary Acidic Protein; 0 / Nerve Growth Factors; 0 / Neural Cell Adhesion Molecule L1; 0 / S100 Calcium Binding Protein beta Subunit; 0 / S100 Proteins
  •  go-up   go-down


72. Gagnon A, Antunes TT, Ly T, Pongsuwan P, Gavin C, Lochnan HA, Sorisky A: Thyroid-stimulating hormone stimulates lipolysis in adipocytes in culture and raises serum free fatty acid levels in vivo. Metabolism; 2010 Apr;59(4):547-53
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Using differentiated 3T3-L1 adipocytes as well as primary human adipocytes, we characterized the lipolytic action of TSH with dose-response and time-course studies, and compared it with isoproterenol.
  • [MeSH-minor] 3T3-L1 Cells. Adult. Animals. Carrier Proteins. Cyclic AMP-Dependent Protein Kinases / physiology. Female. Humans. Male. Mice. Middle Aged. Phosphoproteins / metabolism. Phosphorylation. Sterol Esterase / metabolism. Thyroidectomy

  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19846175.001).
  • [ISSN] 1532-8600
  • [Journal-full-title] Metabolism: clinical and experimental
  • [ISO-abbreviation] Metab. Clin. Exp.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carrier Proteins; 0 / Fatty Acids, Nonesterified; 0 / Phosphoproteins; 0 / perilipin 1; 9002-71-5 / Thyrotropin; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases; EC 3.1.1.13 / Sterol Esterase
  •  go-up   go-down


73. Leon S, Sánchez R, Patarroyo MA, Camargo M, Mejia A, Urquiza M, Patarroyo ME: Prevalence of HPV-DNA and anti-HPV antibodies in women from Girardot, Colombia. Sex Transm Dis; 2009 May;36(5):290-6
Immune Epitope Database and Analysis Resource. gene/protein/disease-specific - Related Immune Epitope Information .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Nine hundred fifty-three women attending their regular Pap smear control voluntarily provided cervical cells and blood samples for HPV-DNA analysis and ELISA detection of anti-L1 peptides and virus-like particles (VLPs) antibodies after answering a questionnaire regarding sexual behaviors, number of births, smoking habits, and socio-demographic background.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Amino Acid Sequence. Cervical Intraepithelial Neoplasia / epidemiology. Cervical Intraepithelial Neoplasia / virology. Colombia / epidemiology. Enzyme-Linked Immunosorbent Assay. Epitopes / immunology. Female. Humans. Mass Screening. Middle Aged. Molecular Sequence Data. Peptides / immunology. Rural Population. Seroepidemiologic Studies. Socioeconomic Factors. Uterine Cervical Neoplasms / epidemiology. Uterine Cervical Neoplasms / virology. Virion / immunology

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19295467.001).
  • [ISSN] 1537-4521
  • [Journal-full-title] Sexually transmitted diseases
  • [ISO-abbreviation] Sex Transm Dis
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Viral; 0 / Capsid Proteins; 0 / DNA, Viral; 0 / Epitopes; 0 / L1 protein, Human papillomavirus type 16; 0 / Oncogene Proteins, Viral; 0 / Peptides
  •  go-up   go-down


74. Achard V, Boullu-Ciocca S, Desbriere R, Nguyen G, Grino M: Renin receptor expression in human adipose tissue. Am J Physiol Regul Integr Comp Physiol; 2007 Jan;292(1):R274-82
antibodies-online. View related products from antibodies-online.com (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Double-labeling immunohistochemistry of human adipose tissue sections revealed that RenR was colocalized with renin, whereas incubation of 3T3-L1, a preadipocyte cell line, with renin stimulated the phosphorylation state of the intracellular signaling pathway ERK 1/2, and short exposure of human adipose stromal cells in primary culture to renin was followed by a long-lasting dose-dependent increase of angiotensin I generation, indicating that adipose RenR is functional.
  • [MeSH-minor] 3T3-L1 Cells. Adipocytes / drug effects. Adipocytes / metabolism. Adolescent. Adult. Angiotensin I / biosynthesis. Animals. Cell Differentiation / physiology. Cells, Cultured. Extracellular Signal-Regulated MAP Kinases / metabolism. Female. Humans. Immunohistochemistry. In Situ Hybridization. Mice. Middle Aged. Obesity / metabolism. Obesity / pathology. Phosphorylation. RNA, Messenger / biosynthesis. Reverse Transcriptase Polymerase Chain Reaction. Signal Transduction / drug effects. Stromal Cells / metabolism

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17197644.001).
  • [ISSN] 0363-6119
  • [Journal-full-title] American journal of physiology. Regulatory, integrative and comparative physiology
  • [ISO-abbreviation] Am. J. Physiol. Regul. Integr. Comp. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ATP6AP2 protein, human; 0 / RNA, Messenger; 0 / Receptors, Cell Surface; 9041-90-1 / Angiotensin I; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 3.6.1.- / Vacuolar Proton-Translocating ATPases
  •  go-up   go-down


75. Goldfine AB, Crunkhorn S, Costello M, Gami H, Landaker EJ, Niinobe M, Yoshikawa K, Lo D, Warren A, Jimenez-Chillaron J, Patti ME: Necdin and E2F4 are modulated by rosiglitazone therapy in diabetic human adipose and muscle tissue. Diabetes; 2006 Mar;55(3):640-50
Hazardous Substances Data Bank. ROSIGLITAZONE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To determine whether changes were related to an effect of the drug or adipogenesis, we evaluated the impact of rosiglitazone and differentiation independently in 3T3-L1 adipocytes.
  • [MeSH-minor] 3T3-L1 Cells. Adult. Aged. Animals. Cell Differentiation. Female. Humans. Male. Mice. Mice, Inbred ICR. Middle Aged. RNA, Messenger / analysis

  • MedlinePlus Health Information. consumer health - Diabetes Medicines.
  • MedlinePlus Health Information. consumer health - Diabetes Type 2.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16505226.001).
  • [ISSN] 0012-1797
  • [Journal-full-title] Diabetes
  • [ISO-abbreviation] Diabetes
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / K08-DK-02526; United States / NIDDK NIH HHS / DK / K23-DK-02795; United States / NCRR NIH HHS / RR / M01-RR-01032; United States / NIDDK NIH HHS / DK / P30-DK-36836; United States / NIDDK NIH HHS / DK / R01-DK-060837; United States / NIDDK NIH HHS / DK / R01-DK-33201; United States / NIDDK NIH HHS / DK / R01-DK-45935; United States / NIDDK NIH HHS / DK / R01-DK-62948
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / E2F4 Transcription Factor; 0 / E2F4 protein, human; 0 / Hypoglycemic Agents; 0 / Nerve Tissue Proteins; 0 / Nuclear Proteins; 0 / RNA, Messenger; 0 / Thiazolidinediones; 0 / necdin; 05V02F2KDG / rosiglitazone
  •  go-up   go-down


76. Hsu HF, Tsou TC, Chao HR, Shy CG, Kuo YT, Tsai FY, Yeh SC, Ko YC: Effects of arecoline on adipogenesis, lipolysis, and glucose uptake of adipocytes-A possible role of betel-quid chewing in metabolic syndrome. Toxicol Appl Pharmacol; 2010 Jun 15;245(3):370-7
Hazardous Substances Data Bank. GLYCERIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Using mouse 3T3-L1 preadipocytes, we showed that arecoline inhibited adipogenesis as determined by oil droplet formation and adipogenic marker gene expression.
  • The effects of arecoline on lipolysis of differentiated 3T3-L1 adipocytes were determined by the glycerol release assay, indicating that arecoline induced lipolysis in an adenylyl cyclase-dependent manner.
  • The diabetogenic effects of arecoline on differentiated 3T3-L1 adipocytes were evaluated by the glucose uptake assay, revealing that > or = 300 microM arecoline significantly attenuated insulin-induced glucose uptake; however, no marked effect on basal glucose uptake was detected.
  • [MeSH-minor] 3T3-L1 Cells. Adenylyl Cyclases / metabolism. Adult. Aged. Animals. Biological Transport. Cell Survival / drug effects. Dose-Response Relationship, Drug. Female. Gene Expression Regulation / drug effects. Glycerol / metabolism. Humans. Hyperlipidemias / blood. Hyperlipidemias / etiology. Insulin / metabolism. Male. Mice. Middle Aged. Nuts. Time Factors. Triglycerides / blood

  • MedlinePlus Health Information. consumer health - Metabolic Syndrome.
  • Hazardous Substances Data Bank. GLUCOSE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20406654.001).
  • [ISSN] 1096-0333
  • [Journal-full-title] Toxicology and applied pharmacology
  • [ISO-abbreviation] Toxicol. Appl. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Insulin; 0 / Triglycerides; 4ALN5933BH / Arecoline; EC 4.6.1.1 / Adenylyl Cyclases; IY9XDZ35W2 / Glucose; PDC6A3C0OX / Glycerol
  •  go-up   go-down


77. Kopp A, Buechler C, Bala M, Neumeier M, Schölmerich J, Schäffler A: Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3. Endocrinology; 2010 Mar;151(3):1097-108
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Experiments using specific ligands for all known TLRs were performed in murine 3T3-L1 adipocytes and in human adipocytes isolated from noninflamed and inflamed adipose tissue.
  • [MeSH-minor] 3T3-L1 Cells. Adipose Tissue / immunology. Adipose Tissue / metabolism. Adult. Animals. Anthracenes. Butadienes. Extracellular Signal-Regulated MAP Kinases / metabolism. Female. Humans. Inflammation / metabolism. Insulin / metabolism. Interferon Regulatory Factor-3 / metabolism. JNK Mitogen-Activated Protein Kinases / antagonists & inhibitors. JNK Mitogen-Activated Protein Kinases / metabolism. Lipopolysaccharides. MAP Kinase Kinase 1 / antagonists & inhibitors. MAP Kinase Kinase 1 / metabolism. MAP Kinase Kinase 2 / antagonists & inhibitors. MAP Kinase Kinase 2 / metabolism. Male. Mice. Myeloid Differentiation Factor 88. Nitriles. Phosphorylation. RNA, Messenger / metabolism

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Endocrinology. 2012 Feb;153(2):1000
  • (PMID = 20130114.001).
  • [ISSN] 1945-7170
  • [Journal-full-title] Endocrinology
  • [ISO-abbreviation] Endocrinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anthracenes; 0 / Butadienes; 0 / Ccl2 protein, mouse; 0 / Chemokine CCL2; 0 / Insulin; 0 / Interferon Regulatory Factor-3; 0 / Interleukin-6; 0 / Irf3 protein, mouse; 0 / Lipopolysaccharides; 0 / Myd88 protein, mouse; 0 / Myeloid Differentiation Factor 88; 0 / Nitriles; 0 / RNA, Messenger; 0 / Toll-Like Receptors; 0 / U 0126; 0 / anthra(1,9-cd)pyrazol-6(2H)-one; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 2.7.11.24 / JNK Mitogen-Activated Protein Kinases; EC 2.7.12.2 / MAP Kinase Kinase 1; EC 2.7.12.2 / MAP Kinase Kinase 2
  •  go-up   go-down


78. Lowy DR, Schiller JT: Prophylactic human papillomavirus vaccines. J Clin Invest; 2006 May;116(5):1167-73
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This Review examines prophylactic HPV subunit vaccines based on the ability of the viral L1 capsid protein to form virus-like particles (VLPs) that induce high levels of neutralizing antibodies.

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Natl Cancer Inst Monogr. 2003;(31):14-9 [12807940.001]
  • [Cites] Obstet Gynecol. 2006 Jan;107(1):18-27 [16394035.001]
  • [Cites] J Natl Cancer Inst Monogr. 2003;(31):57-65 [12807947.001]
  • [Cites] Arch Pathol Lab Med. 2003 Aug;127(8):935-9 [12873164.001]
  • [Cites] J Natl Cancer Inst. 2003 Aug 6;95(15):1128-37 [12902442.001]
  • [Cites] Int J Cancer. 2004 Apr 10;109(3):418-24 [14961581.001]
  • [Cites] Lancet. 2004 May 8;363(9420):1488-9 [15135592.001]
  • [Cites] Virology. 2004 Jun 20;324(1):17-27 [15183049.001]
  • [Cites] Int J Cancer. 2004 Aug 20;111(2):278-85 [15197783.001]
  • [Cites] Hum Pathol. 2004 Aug;35(8):971-82 [15297964.001]
  • [Cites] J Virol. 1993 Jan;67(1):315-22 [8380079.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12180-4 [1334560.001]
  • [Cites] J Virol. 1993 Apr;67(4):1936-44 [8383219.001]
  • [Cites] J Virol. 1993 Dec;67(12):6929-36 [8230414.001]
  • [Cites] J Gen Virol. 1994 Aug;75 ( Pt 8):2075-9 [8046412.001]
  • [Cites] J Virol. 1995 Jun;69(6):3959-63 [7745754.001]
  • [Cites] J Infect Dis. 1995 Jun;171(6):1387-98 [7769272.001]
  • [Cites] J Clin Microbiol. 1995 Aug;33(8):2058-63 [7559948.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11553-7 [8524802.001]
  • [Cites] J Virol. 1996 May;70(5):3298-301 [8627814.001]
  • [Cites] Virology. 1996 May 1;219(1):37-44 [8623552.001]
  • [Cites] J Virol. 1996 Sep;70(9):5875-83 [8709207.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1997 Jun;6(6):387-400 [9184771.001]
  • [Cites] Sex Transm Dis. 1999 Apr;26(4 Suppl):S2-7 [10227693.001]
  • [Cites] J Natl Cancer Inst. 2001 Feb 21;93(4):284-92 [11181775.001]
  • [Cites] J Clin Pathol. 2002 Apr;55(4):244-65 [11919208.001]
  • [Cites] JAMA. 2002 Apr 24;287(16):2120-9 [11966387.001]
  • [Cites] Nat Rev Immunol. 2002 Apr;2(4):291-6 [12002000.001]
  • [Cites] Nat Rev Cancer. 2002 May;2(5):342-50 [12044010.001]
  • [Cites] Dan Med Bull. 2002 Aug;49(3):194-209 [12238281.001]
  • [Cites] N Engl J Med. 2002 Nov 21;347(21):1645-51 [12444178.001]
  • [Cites] N Engl J Med. 2002 Nov 21;347(21):1652-61 [12444179.001]
  • [Cites] Lancet. 2004 Nov 13-19;364(9447):1757-65 [15541448.001]
  • [Cites] J Infect Dis. 2005 Feb 1;191 Suppl 1:S97-106 [15627236.001]
  • [Cites] J Clin Virol. 2005 Mar;32 Suppl 1:S16-24 [15753008.001]
  • [Cites] Expert Rev Vaccines. 2005 Feb;4(1):19-21 [15757469.001]
  • [Cites] Cancer Metastasis Rev. 2005 Jan;24(1):19-34 [15785870.001]
  • [Cites] Lancet Oncol. 2005 May;6(5):271-8 [15863374.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1157-64 [15894666.001]
  • [Cites] Antivir Chem Chemother. 2005;16(3):155-68 [16004079.001]
  • [Cites] J Natl Cancer Inst. 2005 Jul 20;97(14):1072-9 [16030305.001]
  • [Cites] N Engl J Med. 2005 Nov 17;353(20):2101-4 [16291978.001]
  • [Cites] N Engl J Med. 2005 Nov 17;353(20):2158-68 [16291985.001]
  • [Cites] J Pathol. 2006 Jan;208(2):152-64 [16362994.001]
  • [Cites] J Natl Cancer Inst Monogr. 2003;(31):52-6 [12807946.001]
  • (PMID = 16670757.001).
  • [ISSN] 0021-9738
  • [Journal-full-title] The Journal of clinical investigation
  • [ISO-abbreviation] J. Clin. Invest.
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cancer Vaccines; 0 / Capsid Proteins; 0 / L1 protein, Human papillomavirus type 16; 0 / Oncogene Proteins, Viral; 0 / Papillomavirus Vaccines; 0 / Viral Vaccines
  • [Number-of-references] 53
  • [Other-IDs] NLM/ PMC1451224
  •  go-up   go-down


79. Schröder O, Naumann M, Shastri Y, Povse N, Stein J: Prospective evaluation of faecal neutrophil-derived proteins in identifying intestinal inflammation: combination of parameters does not improve diagnostic accuracy of calprotectin. Aliment Pharmacol Ther; 2007 Oct 1;26(7):1035-42
MedlinePlus Health Information. consumer health - Diarrhea.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Eighty-eight adult patients with a history of chronic diarrhoea of unknown origin were screened.
  • [MeSH-major] Diarrhea / etiology. Feces / chemistry. Inflammatory Bowel Diseases / diagnosis. Leukocyte L1 Antigen Complex / analysis
  • [MeSH-minor] Adult. Aged. Biomarkers / analysis. Cohort Studies. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Prospective Studies. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17877510.001).
  • [ISSN] 0269-2813
  • [Journal-full-title] Alimentary pharmacology & therapeutics
  • [ISO-abbreviation] Aliment. Pharmacol. Ther.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Leukocyte L1 Antigen Complex
  •  go-up   go-down


80. Bour S, Daviaud D, Gres S, Lefort C, Prévot D, Zorzano A, Wabitsch M, Saulnier-Blache JS, Valet P, Carpéné C: Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes. Biochimie; 2007 Aug;89(8):916-25
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Both SSAO and MAO were increased from undifferentiated preadipocytes to lipid-laden cells in all the models: 3T3-F442A and 3T3-L1 murine lineages, human SGBS cell strain or human preadipocytes in primary culture.
  • [MeSH-minor] 3T3 Cells. 3T3-L1 Cells. Adult. Animals. Cell Differentiation / genetics. Cell Lineage. Female. Humans. Infant. Mice. Middle Aged. RNA, Messenger / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17400359.001).
  • [ISSN] 0300-9084
  • [Journal-full-title] Biochimie
  • [ISO-abbreviation] Biochimie
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  • [Chemical-registry-number] 0 / RNA, Messenger; EC 1.4.3.21 / Amine Oxidase (Copper-Containing); EC 1.4.3.4 / Monoamine Oxidase
  •  go-up   go-down


81. Elmer S, Meyer M, Jancke L: Simultaneous interpreters as a model for neuronal adaptation in the domain of language processing. Brain Res; 2010 Mar 4;1317:147-56
MedlinePlus Health Information. consumer health - Seniors' Health.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eleven native German SI and controls matched in L2 proficiency and age of acquisition were asked to judge whether auditory presented disyllabic noun pairs both within and across the German (L1) and English (L2) languages were either semantically congruent or incongruent.
  • We revealed enlarged N400 responses in SI while they detected incongruent trials both within the native (L1) and non-native (L2) language and also while they performed the task in the opposite direction as specifically trained (L1 to L2).
  • These enlarged N400 responses in SI suggest a training-induced altered sensitivity to semantic processing within and across L1 and L2.
  • The enlarged N400 responses we revealed in SI to congruent noun pairs during the German-English condition (L1 to L2) may indicate that SI could not benefit from an L1 prime when the target was a L2 word, suggesting additional processing resulting from long-term backwards (L2 to L1) training.
  • [MeSH-minor] Adult. Electroencephalography. Evoked Potentials. Female. Humans. Judgment / physiology. Language. Language Tests. Male. Middle Aged. Occupations. Semantics. Task Performance and Analysis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2009 Elsevier B.V. All rights reserved.
  • (PMID = 20051239.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  •  go-up   go-down


82. Montalto M, Curigliano V, Santoro L, Armuzzi A, Cammarota G, Covino M, Mentella MC, Ancarani F, Manna R, Gasbarrini A, Gasbarrini G: Fecal calprotectin in first-degree relatives of patients with ulcerative colitis. Am J Gastroenterol; 2007 Jan;102(1):132-6
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Colitis, Ulcerative / genetics. Genetic Predisposition to Disease. Leukocyte L1 Antigen Complex / genetics
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Feces / chemistry. Female. Humans. Male. Middle Aged. Statistics, Nonparametric

  • Genetic Alliance. consumer health - Ulcerative Colitis.
  • MedlinePlus Health Information. consumer health - Ulcerative Colitis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17100982.001).
  • [ISSN] 0002-9270
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Leukocyte L1 Antigen Complex
  •  go-up   go-down


83. Chouhy D, Gorosito M, Sánchez A, Serra EC, Bergero A, Fernandez Bussy R, Giri AA: New generic primer system targeting mucosal/genital and cutaneous human papillomaviruses leads to the characterization of HPV 115, a novel Beta-papillomavirus species 3. Virology; 2010 Feb 5;397(1):205-16
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Phylogenetic analysis of partial L1 sequences grouped 2 novel putative types in the Beta-PV, 14 in the Gamma-PV and 1 in the Mu-PV genera.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 Elsevier Inc. All rights reserved.
  • [Cites] J Virol. 1999 Jul;73(7):5282-93 [10364274.001]
  • [Cites] Virology. 1998 Jan 20;240(2):359-65 [9454709.001]
  • [Cites] J Clin Virol. 2005 Mar;32 Suppl 1:S25-33 [15753009.001]
  • [Cites] J Invest Dermatol. 2005 Jul;125(1):93-7 [15982308.001]
  • [Cites] J Pathol. 2006 Jan;208(2):165-75 [16362995.001]
  • [Cites] Int J Cancer. 2006 Mar 1;118(5):1071-6 [16331617.001]
  • [Cites] Virology. 2007 Apr 10;360(2):447-53 [17125811.001]
  • [Cites] J Gen Virol. 2007 May;88(Pt 5):1479-83 [17412976.001]
  • [Cites] Dis Markers. 2007;23(4):247-59 [17627060.001]
  • [Cites] Mol Biol Evol. 2007 Aug;24(8):1596-9 [17488738.001]
  • [Cites] J Infect Dis. 2007 Sep 15;196(6):876-83 [17703418.001]
  • [Cites] J Gen Virol. 2007 Oct;88(Pt 10):2662-9 [17872517.001]
  • [Cites] J Gen Virol. 2008 Oct;89(Pt 10):2467-74 [18796715.001]
  • [Cites] J Gen Virol. 2008 Nov;89(Pt 11):2891-7 [18931088.001]
  • [Cites] J Invest Dermatol. 2008 Dec;128(12):2888-93 [18548109.001]
  • [Cites] J Clin Virol. 2008 Dec;43(4):353-60 [18986829.001]
  • [Cites] J Virol. 2009 Apr;83(7):2907-16 [19153227.001]
  • [Cites] J Gen Virol. 2009 Aug;90(Pt 8):1999-2004 [19386784.001]
  • [Cites] J Virol. 2000 Dec;74(24):11636-41 [11090162.001]
  • [Cites] J Med Virol. 2001 Mar;63(3):259-63 [11170067.001]
  • [Cites] Bioinformatics. 2001 Aug;17(8):754-5 [11524383.001]
  • [Cites] Nat Rev Cancer. 2002 May;2(5):342-50 [12044010.001]
  • [Cites] Oncogene. 2002 Nov 21;21(53):8140-8 [12444549.001]
  • [Cites] J Virol Methods. 2003 Jun 30;110(2):129-36 [12798239.001]
  • [Cites] J Gen Virol. 2003 Jul;84(Pt 7):1881-6 [12810883.001]
  • [Cites] Virology. 2004 Jun 20;324(1):17-27 [15183049.001]
  • [Cites] J Invest Dermatol. 2004 Aug;123(2):388-94 [15245440.001]
  • [Cites] Nature. 1986 Nov 13-19;324(6093):163-6 [3785382.001]
  • [Cites] Arch Dermatol. 1988 Jun;124(6):869-71 [3377516.001]
  • [Cites] J Virol. 1990 Jan;64(1):207-14 [2152813.001]
  • [Cites] J Gen Virol. 1990 Apr;71 ( Pt 4):965-70 [2157805.001]
  • [Cites] J Virol. 1990 Dec;64(12):6121-9 [2173783.001]
  • [Cites] J Virol. 1992 Mar;66(3):1329-35 [1310752.001]
  • [Cites] Biochem Biophys Res Commun. 1995 Jan 5;206(1):97-102 [7818556.001]
  • [Cites] Biochem J. 1996 Oct 1;319 ( Pt 1):229-39 [8870673.001]
  • [Cites] J Gen Virol. 1999 Sep;80 ( Pt 9):2437-43 [10501499.001]
  • (PMID = 19948351.001).
  • [ISSN] 1096-0341
  • [Journal-full-title] Virology
  • [ISO-abbreviation] Virology
  • [Language] ENG
  • [Databank-accession-numbers] GENBANK/ FJ947079/ FJ947080/ FJ947081/ FJ947082/ FJ969896/ FJ969897/ FJ969898/ FJ969899/ FJ969900/ FJ969901/ FJ969902/ FJ969903/ FJ969904/ FJ969905/ FJ969906/ FJ969907/ FJ969908/ FJ969909/ FJ969910/ FJ969911/ FJ969912/ FJ969913/ FJ969914
  • [Grant] United States / FIC NIH HHS / TW / D43 TW001037; United States / FIC NIH HHS / TW / D43 TW0010137; United States / FIC NIH HHS / TW / D43 TW001037-06; United States / FIC NIH HHS / TW / D43 TW010137; United States / FIC NIH HHS / TW / TW001037-06
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Capsid Proteins; 0 / DNA Primers; 0 / DNA, Viral; 0 / HPV L1 protein, Human papillomavirus; 0 / Oncogene Proteins, Viral
  • [Other-IDs] NLM/ NIHMS159950; NLM/ PMC2813930
  •  go-up   go-down


84. De Braekeleer E, Basinko A, Douet-Guilbert N, Morel F, Le Bris MJ, Berthou C, Morice P, Férec C, De Braekeleer M: Cytogenetics in pre-B and B-cell acute lymphoblastic leukemia: a study of 208 patients diagnosed between 1981 and 2008. Cancer Genet Cytogenet; 2010 Jul 1;200(1):8-15
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytogenetics in pre-B and B-cell acute lymphoblastic leukemia: a study of 208 patients diagnosed between 1981 and 2008.
  • The detection of chromosome abnormalities by conventional cytogenetics, now combined with analyses using fluorescence in situ hybridization (FISH), is an important component in assessing the risk stratification of acute lymphoblastic leukemia (ALL).
  • Chromosome abnormalities were observed in 82.9% of L1/L2 ALL patients and in 83.3% of L3 patients with successful analysis at diagnosis.
  • [MeSH-major] Chromosome Aberrations. Leukemia, B-Cell / genetics. Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Histone-Lysine N-Methyltransferase. Humans. Middle Aged. Myeloid-Lymphoid Leukemia Protein / genetics. Recurrence. Time Factors. Translocation, Genetic

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20513528.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MLL protein, human; 149025-06-9 / Myeloid-Lymphoid Leukemia Protein; EC 2.1.1.43 / Histone-Lysine N-Methyltransferase
  •  go-up   go-down


85. Neely ST, Johnson TA, Gorga MP: Distortion-product otoacoustic emission measured with continuously varying stimulus level. J Acoust Soc Am; 2005 Mar;117(3 Pt 1):1248-59
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Continuous-level measurements were used to determine the optimal L1 for each L2 in individual subjects (N= 20) at f2 = 1, 2, 4, and 8 kHz by using a Lissajous path that covered a wide range of stimulus levels.
  • The optimal L1 (defined as the L1 that resulted in the largest DPOAE for each L2) varied across subjects and across frequency.
  • The optimal difference between L1 and L2 decreased with increasing L2 at all frequencies, and increased with frequency when L2 was low.
  • When the optimal L1 was determined individually for each ear, the DPOAE levels were larger and less variable than those obtained using the equation for L1 suggested by Kummer et al. [J. Acoust. Soc. Am.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] ASHA Suppl. 1990 Apr;(2):17-24 [1970249.001]
  • [Cites] J Acoust Soc Am. 1990 Aug;88(2):821-39 [2212308.001]
  • [Cites] J Acoust Soc Am. 1990 Aug;88(2):840-9 [2212309.001]
  • [Cites] J Acoust Soc Am. 1991 Jan;89(1):280-6 [2002169.001]
  • [Cites] J Acoust Soc Am. 1995 Apr;97(4):2346-58 [7714254.001]
  • [Cites] J Acoust Soc Am. 1995 Apr;97(4):2359-77 [7714255.001]
  • [Cites] Hear Res. 1995 Feb;82(2):225-43 [7775288.001]
  • [Cites] J Acoust Soc Am. 1989 Jan;85(1):220-9 [2921404.001]
  • [Cites] J Neurophysiol. 1969 Jul;32(4):613-36 [5810617.001]
  • [Cites] J Acoust Soc Am. 2004 Jun;115(6):3081-91 [15237833.001]
  • [Cites] J Acoust Soc Am. 2003 Jun;113(6):3275-84 [12822800.001]
  • [Cites] J Acoust Soc Am. 2003 May;113(5):2762-72 [12765394.001]
  • [Cites] J Acoust Soc Am. 2002 Dec;112(6):2910-20 [12509012.001]
  • [Cites] J Acoust Soc Am. 2002 Oct;112(4):1545-60 [12398461.001]
  • [Cites] J Acoust Soc Am. 2002 Apr;111(4):1810-8 [12002865.001]
  • [Cites] J Acoust Soc Am. 2002 Jan;111(1 Pt 1):249-60 [11831799.001]
  • [Cites] J Acoust Soc Am. 1998 Jun;103(6):3431-44 [9637030.001]
  • [Cites] Physiol Rev. 2001 Jul;81(3):1305-52 [11427697.001]
  • [Cites] Ear Hear. 1997 Dec;18(6):440-55 [9416447.001]
  • [Cites] J Acoust Soc Am. 2000 Jun;107(6):3317-32 [10875377.001]
  • [Cites] Hear Res. 2000 Aug;146(1-2):47-56 [10913883.001]
  • [Cites] J Assoc Res Otolaryngol. 2001 Mar;2(1):31-40 [11545148.001]
  • (PMID = 15807014.001).
  • [ISSN] 0001-4966
  • [Journal-full-title] The Journal of the Acoustical Society of America
  • [ISO-abbreviation] J. Acoust. Soc. Am.
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / P30 DC004662; United States / NIDCD NIH HHS / DC / R01 DC002251; United States / NIDCD NIH HHS / DC / T32 DC000013; United States / NIDCD NIH HHS / DC / T32-DC00013; United States / NIDCD NIH HHS / DC / P30-DC04662; United States / NIDCD NIH HHS / DC / R01-DC02251
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS2046; NLM/ PMC1414785
  •  go-up   go-down


86. Montalto M, Santoro L, Curigliano V, D'Onofrio F, Cammarota G, Panunzi S, Ricci R, Gallo A, Grieco A, Gasbarrini A, Gasbarrini G: Faecal calprotectin concentrations in untreated coeliac patients. Scand J Gastroenterol; 2007 Aug;42(8):957-61
MedlinePlus Health Information. consumer health - Celiac Disease.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Thirty healthy adult volunteers participated as the control group.
  • [MeSH-major] Celiac Disease / diagnosis. Feces / chemistry. Leukocyte L1 Antigen Complex / analysis
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Pilot Projects

  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17613925.001).
  • [ISSN] 0036-5521
  • [Journal-full-title] Scandinavian journal of gastroenterology
  • [ISO-abbreviation] Scand. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Leukocyte L1 Antigen Complex
  •  go-up   go-down


87. Yoshikawa H: [Progress and challenges on HPV vaccination]. Uirusu; 2009 Dec;59(2):243-8
International Agency for Research on Cancer - Screening Group. diagnostics - A practical manual on visual screening for cervical neoplasia .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18. Human papillomavirus 16 / immunology. Human papillomavirus 18 / immunology. Humans. Young Adult

  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • International Agency for Research on Cancer - Screening Group. diagnostics - Planning and Implementing Cervical Cancer Prevention and Control Programs: A Manual for Managers .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20218332.001).
  • [ISSN] 0042-6857
  • [Journal-full-title] Uirusu
  • [ISO-abbreviation] Uirusu
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; 0 / Papillomavirus Vaccines; 0 / human papillomavirus vaccine, L1 type 16, 18
  • [Number-of-references] 13
  •  go-up   go-down


88. Chakraborty R, Goffman L, Smith A: Physiological indices of bilingualism: oral-motor coordination and speech rate in Bengali-English speakers. J Speech Lang Hear Res; 2008 Apr;51(2):321-32
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • For all 21 speakers, lip movement variability was assessed based on productions of Bengali (L1; 1st language) and English (L2; 2nd language) sentences.
  • Lip movement variability and speech rate were evaluated for both of these groups across L1 and L2 sentences.
  • RESULTS: Surprisingly, adult bilingual speakers produced equally consistent speech movement patterns in their production of L1 and L2.
  • When groups were sorted according to proficiency, highly proficient speakers were marginally more variable in their L1.
  • Consistent with previous studies, movement durations were longer for less proficient speakers in both L1 and L2.
  • INTERPRETATION: In contrast to those of child learners, the speech motor systems of adult L2 speakers show a high degree of consistency.
  • The proficiency results suggest bidirectional interactions across L1 and L2, which is consistent with hypotheses regarding interference and the sharing of phonological space.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Exp Brain Res. 1995;104(3):493-501 [7589300.001]
  • [Cites] J Speech Lang Hear Res. 1998 Feb;41(1):18-30 [9493730.001]
  • [Cites] J Speech Lang Hear Res. 1999 Dec;42(6):1499-517 [10599629.001]
  • [Cites] J Speech Lang Hear Res. 2000 Feb;43(1):277-86 [10668669.001]
  • [Cites] J Speech Lang Hear Res. 1999 Aug;42(4):1003-15 [10450917.001]
  • [Cites] J Speech Lang Hear Res. 2000 Apr;43(2):521-36 [10757701.001]
  • [Cites] J Speech Lang Hear Res. 2000 Apr;43(2):560-73 [10757704.001]
  • [Cites] J Speech Lang Hear Res. 2002 Dec;45(6):1119-33 [12546482.001]
  • [Cites] J Speech Lang Hear Res. 2003 Oct;46(5):1234-46 [14575355.001]
  • [Cites] Dev Psychobiol. 2004 Jul;45(1):22-33 [15229873.001]
  • [Cites] J Speech Hear Res. 1985 Mar;28(1):8-15 [3982001.001]
  • [Cites] Exp Brain Res. 1987;68(1):37-46 [3691696.001]
  • [Cites] J Acoust Soc Am. 1988 Nov;84(5):1639-52 [3209769.001]
  • [Cites] J Acoust Soc Am. 1992 Jan;91(1):370-89 [1737886.001]
  • [Cites] J Speech Hear Res. 1993 Feb;36(1):41-54 [8450664.001]
  • [Cites] J Acoust Soc Am. 1995 May;97(5 Pt 1):3125-34 [7759652.001]
  • [Cites] J Speech Hear Res. 1995 Dec;38(6):1252-9 [8747818.001]
  • [Cites] Lang Speech. 1995 Jul-Sep;38 ( Pt 3):289-306 [8816082.001]
  • (PMID = 18367680.001).
  • [ISSN] 1092-4388
  • [Journal-full-title] Journal of speech, language, and hearing research : JSLHR
  • [ISO-abbreviation] J. Speech Lang. Hear. Res.
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / DC004826-05; United States / NIDCD NIH HHS / DC / R01 DC004826; United States / NIDCD NIH HHS / DC / DC04826; United States / NIDCD NIH HHS / DC / R01 DC004826-05
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS155184; NLM/ PMC2782381
  •  go-up   go-down


89. Miyakoshi N, Hongo M, Kasukawa Y, Shimada Y: Huge thoracolumbar extradural arachnoid cyst excised by recapping T-saw laminoplasty. Spine J; 2010 Nov;10(11):e14-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • En bloc recapping T-saw laminoplasty of T12-L2 including the T12-L1 and L1-L2 facet joints was performed to obtain extensive exposure and preserve posterior stability.
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20970735.001).
  • [ISSN] 1878-1632
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


90. Palmer SD, van Hooff JC, Havelka J: Language representation and processing in fluent bilinguals: electrophysiological evidence for asymmetric mapping in bilingual memory. Neuropsychologia; 2010 Apr;48(5):1426-37
MedlinePlus Health Information. consumer health - Memory.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Specifically, the N400 effect was larger during backward translation (L2-L1) than during forward translation (L1-L2) in both groups of bilinguals.
  • [MeSH-minor] Adult. Evoked Potentials / physiology. Female. Humans. Male. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2010. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20138064.001).
  • [ISSN] 1873-3514
  • [Journal-full-title] Neuropsychologia
  • [ISO-abbreviation] Neuropsychologia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


91. Ho GT, Lee HM, Brydon G, Ting T, Hare N, Drummond H, Shand AG, Bartolo DC, Wilson RG, Dunlop MG, Arnott ID, Satsangi J: Fecal calprotectin predicts the clinical course of acute severe ulcerative colitis. Am J Gastroenterol; 2009 Mar;104(3):673-8
Hazardous Substances Data Bank. Infliximab .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fecal calprotectin predicts the clinical course of acute severe ulcerative colitis.
  • We aim to investigate fecal calprotectin (FC) as a biomarker in predicting the clinical course of acute severe ulcerative colitis (ASUC).
  • [MeSH-major] Colitis, Ulcerative / diagnosis. Feces / chemistry. Leukocyte L1 Antigen Complex / analysis
  • [MeSH-minor] Acute Disease. Adult. Antibodies, Monoclonal / therapeutic use. Biomarkers / analysis. Colectomy. Female. Gastrointestinal Agents / therapeutic use. Glucocorticoids / therapeutic use. Humans. Infliximab. Male. Middle Aged. Prognosis

  • Genetic Alliance. consumer health - Ulcerative Colitis.
  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • MedlinePlus Health Information. consumer health - Ulcerative Colitis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19262524.001).
  • [ISSN] 1572-0241
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0701898; United Kingdom / Medical Research Council / / MC/ U127527198; United Kingdom / Medical Research Council / / G0800759; United Kingdom / Chief Scientist Office / / CZB/4/540; United Kingdom / Wellcome Trust / / ; United Kingdom / Medical Research Council / / G0600329
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Biomarkers; 0 / Gastrointestinal Agents; 0 / Glucocorticoids; 0 / Leukocyte L1 Antigen Complex; B72HH48FLU / Infliximab
  •  go-up   go-down


92. Pratelli L, Verri E, Fortini M, Marconi S, Zolezzi C, Fornasari PM, Gamberini MR, De Sanctis V: Chelation therapy and bone metabolism markers in thalassemia major. J Pediatr Endocrinol Metab; 2006 Nov;19(11):1335-42
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of our study was to investigate the effects of subcutaneous desferrioxamine (DFX) and oral deferiprone (L1) therapy on bone metabolism markers in patients with thalassemia major.
  • In conclusion, the study of bone metabolism markers in adult patients with thalassemia reveals a complex behavior with an increase in bone resorption indexes.
  • In particular, TGFbeta1 was higher in patients with thalassemia receiving L1 treatment.
  • [MeSH-minor] Adult. Alkaline Phosphatase / metabolism. Bone Resorption / metabolism. Case-Control Studies. Cytokines / blood. Female. Humans. Intercellular Signaling Peptides and Proteins / blood. Male. Osteocalcin / metabolism. Osteoporosis / etiology. Osteoporosis / metabolism. Parathyroid Hormone / metabolism. Risk Factors. Vitamin D / analogs & derivatives. Vitamin D / metabolism

  • Genetic Alliance. consumer health - Thalassemia.
  • Genetic Alliance. consumer health - Beta Thalassemia.
  • Hazardous Substances Data Bank. DESFERRIOXAMINE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17220062.001).
  • [ISSN] 0334-018X
  • [Journal-full-title] Journal of pediatric endocrinology & metabolism : JPEM
  • [ISO-abbreviation] J. Pediatr. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cytokines; 0 / Intercellular Signaling Peptides and Proteins; 0 / Iron Chelating Agents; 0 / Parathyroid Hormone; 0 / Pyridones; 0 / Siderophores; 104982-03-8 / Osteocalcin; 1406-16-2 / Vitamin D; 2BTY8KH53L / deferiprone; 64719-49-9 / 25-hydroxyvitamin D; 66772-14-3 / 1,25-dihydroxyvitamin D; EC 3.1.3.1 / Alkaline Phosphatase; J06Y7MXW4D / Deferoxamine
  •  go-up   go-down


93. Stone J, Ding J, Warren RM, Duffy SW: Predicting breast cancer risk using mammographic density measurements from both mammogram sides and views. Breast Cancer Res Treat; 2010 Nov;124(2):551-4
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Case-Control Studies. England. Female. Humans. Logistic Models. Middle Aged. Odds Ratio. Predictive Value of Tests. Risk Assessment. Risk Factors

  • Genetic Alliance. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Mammography.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20544272.001).
  • [ISSN] 1573-7217
  • [Journal-full-title] Breast cancer research and treatment
  • [ISO-abbreviation] Breast Cancer Res. Treat.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


94. Liu H, Hu Z, Guo T, Peng D: Speaking words in two languages with one brain: neural overlap and dissociation. Brain Res; 2010 Feb 26;1316:75-82
SciCrunch. NeuroSynth: Data: Activation Foci .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The present study investigated the neural overlap and dissociation underlying overt word production in the first language (L1) and second language (L2).
  • Twenty-four Chinese-English bilinguals named pictures in either L1 or L2 while being scanned with functional magnetic resonance imaging (fMRI).
  • When comparing picture naming in L2 to naming in L1, increased activity in the left inferior frontal gyrus, bilateral supplementary motor areas (SMA), left precentral gyrus, left lingual gyrus, left cuneus, bilateral putamen, bilateral globus pallidus, bilateral caudate and bilateral cerebellum were observed.
  • This suggested that word production in L2 is less automatic and needs to recruit more neural resources for lexical retrieval, articulatory processing and cognitive control than in L1.
  • In contrast, picture naming in L1 relative to picture naming in L2 revealed increased activity in the right putamen and right globus pallidus probably due to different phonological features between Chinese and English.
  • In addition, the conjunction analysis, for the first time, revealed the common neural correlates underlying picture naming in L1 and L2.
  • [MeSH-minor] Brain Mapping. Female. Humans. Language Tests. Magnetic Resonance Imaging. Male. Neural Pathways / physiology. Neuropsychological Tests. Pattern Recognition, Visual / physiology. Photic Stimulation. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 Elsevier B.V. All rights reserved.
  • (PMID = 20026317.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  •  go-up   go-down


95. Lemhöfer K, Dijkstra T, Schriefers H, Baayen RH, Grainger J, Zwitserlood P: Native language influences on word recognition in a second language: a megastudy. J Exp Psychol Learn Mem Cogn; 2008 Jan;34(1):12-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Many studies have reported that word recognition in a second language (L2) is affected by the native language (L1).
  • An additional comparison of the bilingual data with a native control group showed that there are subtle but significant differences between L1 and L2 processing.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] PsycINFO Database Record (c) 2008 APA, all rights reserved.
  • (PMID = 18194052.001).
  • [ISSN] 0278-7393
  • [Journal-full-title] Journal of experimental psychology. Learning, memory, and cognition
  • [ISO-abbreviation] J Exp Psychol Learn Mem Cogn
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / HD043251-03; United States / NICHD NIH HHS / HD / R01 HD043251-03; United States / NICHD NIH HHS / HD / R01 HD043251-04; United States / NICHD NIH HHS / HD / R01 HD043251; United States / NICHD NIH HHS / HD / HD043251-04; United States / NICHD NIH HHS / HD / R01 HD043251-05
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


96. Langhorst J, Elsenbruch S, Mueller T, Rueffer A, Spahn G, Michalsen A, Dobos GJ: Comparison of 4 neutrophil-derived proteins in feces as indicators of disease activity in ulcerative colitis. Inflamm Bowel Dis; 2005 Dec;11(12):1085-91
MedlinePlus Health Information. consumer health - Ulcerative Colitis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Colitis, Ulcerative / diagnosis. Feces / chemistry. Lactoferrin / analysis. Leukocyte Elastase / analysis. Leukocyte L1 Antigen Complex / analysis. Muramidase / analysis
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. ROC Curve. Sensitivity and Specificity

  • Genetic Alliance. consumer health - Ulcerative Colitis.
  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16306771.001).
  • [ISSN] 1078-0998
  • [Journal-full-title] Inflammatory bowel diseases
  • [ISO-abbreviation] Inflamm. Bowel Dis.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Leukocyte L1 Antigen Complex; EC 3.2.1.17 / Muramidase; EC 3.4.21.- / Lactoferrin; EC 3.4.21.37 / Leukocyte Elastase
  •  go-up   go-down


97. Aonurm-Helm A, Berezin V, Bock E, Zharkovsky A: NCAM-mimetic, FGL peptide, restores disrupted fibroblast growth factor receptor (FGFR) phosphorylation and FGFR mediated signaling in neural cell adhesion molecule (NCAM)-deficient mice. Brain Res; 2010 Jan 14;1309:1-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Also, we found that Fyn(Tyr530), Raf1, MAP kinases and Akt kinase phosphorylation in adult animals is not affected by NCAM deficiency but interestingly, we found an over-expression of another cell adhesion molecule L1.
  • [MeSH-minor] Animals. Calcium-Calmodulin-Dependent Protein Kinase Type 2 / metabolism. Calcium-Calmodulin-Dependent Protein Kinase Type 4 / metabolism. Down-Regulation / genetics. Gene Expression Regulation, Enzymologic / drug effects. Gene Expression Regulation, Enzymologic / physiology. MAP Kinase Signaling System / drug effects. MAP Kinase Signaling System / physiology. Mice. Mice, Knockout. Neural Cell Adhesion Molecule L1 / genetics. Neural Cell Adhesion Molecule L1 / metabolism. Phosphorylation / drug effects. Proto-Oncogene Proteins c-akt / metabolism. Proto-Oncogene Proteins c-fyn / metabolism. Proto-Oncogene Proteins c-raf / metabolism. Up-Regulation / drug effects. Up-Regulation / physiology

  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19909731.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / NCAM protein (681-695), human; 0 / Neural Cell Adhesion Molecule L1; 0 / Neural Cell Adhesion Molecules; EC 2.7.10.1 / Fgfr1 protein, mouse; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 1; EC 2.7.10.2 / Fyn protein, mouse; EC 2.7.10.2 / Proto-Oncogene Proteins c-fyn; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 2.7.11.1 / Proto-Oncogene Proteins c-raf; EC 2.7.11.17 / Calcium-Calmodulin-Dependent Protein Kinase Type 2; EC 2.7.11.17 / Calcium-Calmodulin-Dependent Protein Kinase Type 4; EC 2.7.11.17 / Camk4 protein, mouse
  •  go-up   go-down


98. Carroccio A, Rocco P, Rabitti PG, Di Prima L, Forte GB, Cefalù AB, Pisello F, Geraci G, Uomo G: Plasma calprotectin levels in patients suffering from acute pancreatitis. Dig Dis Sci; 2006 Oct;51(10):1749-53
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plasma calprotectin levels in patients suffering from acute pancreatitis.
  • Calprotectin (Cal) concentration is elevated in acute inflammatory reactions and its increase in the plasma suggests a diagnostic potential for Cal assay.
  • This study aimed (a) to evaluate the Cal plasma levels in patients suffering from acute pancreatitis (AP) and (b) to assess whether early assay of Cal plasma levels can be helpful in assessment of the severity of AP.
  • [MeSH-major] Leukocyte L1 Antigen Complex / blood. Pancreatitis / blood
  • [MeSH-minor] Adult. Aged. Biomarkers / blood. C-Reactive Protein / metabolism. Case-Control Studies. Enzyme-Linked Immunosorbent Assay. Female. Humans. Male. Middle Aged. Severity of Illness Index. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Pancreatitis.
  • MedlinePlus Health Information. consumer health - Pancreatitis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Scand J Clin Lab Invest. 1984 Nov;44(7):629-34 [6531650.001]
  • [Cites] Lancet. 1990 Sep 29;336(8718):763-5 [1976144.001]
  • [Cites] Scand J Immunol. 1994 Dec;40(6):675-80 [7997858.001]
  • [Cites] Lancet. 1995 Sep 9;346(8976):663-7 [7658819.001]
  • [Cites] Arch Dis Child. 1996 Feb;74(2):136-9 [8660076.001]
  • [Cites] Gut. 2000 Jun;46(6):795-800 [10807890.001]
  • [Cites] Lupus. 1993 Feb;2(1):47-50 [8485559.001]
  • [Cites] Aliment Pharmacol Ther. 1998 Mar;12(3):237-45 [9570258.001]
  • [Cites] Br J Surg. 2001 Feb;88(2):216-21 [11167870.001]
  • [Cites] Br J Surg. 1989 Feb;76(2):177-81 [2467718.001]
  • [Cites] J Rheumatol. 1991 Jan;18(1):133-8 [2023183.001]
  • [Cites] Gut. 2000 Oct;47(4):506-13 [10986210.001]
  • [Cites] Br J Surg. 1978 May;65(5):337-41 [348250.001]
  • [Cites] JOP. 2002 Sep;3(5):116-25 [12221326.001]
  • [Cites] Clin Mol Pathol. 1996 Apr;49(2):M74-9 [16696054.001]
  • [Cites] Am J Physiol. 1995 May;268(5 Pt 1):C1241-51 [7762618.001]
  • [Cites] Lancet. 2000 Jun 3;355(9219):1955-60 [10859041.001]
  • [Cites] Clin Chem. 2003 Jun;49(6 Pt 1):861-7 [12765980.001]
  • [Cites] Mol Pathol. 1997 Jun;50(3):113-23 [9292145.001]
  • [Cites] Arch Surg. 1993 May;128(5):586-90 [8489394.001]
  • [Cites] Dig Liver Dis. 2001 Mar;33(2):192-201 [11346150.001]
  • [Cites] Dig Dis Sci. 1995 Apr;40(4):734-8 [7720462.001]
  • (PMID = 16964544.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Leukocyte L1 Antigen Complex; 9007-41-4 / C-Reactive Protein
  •  go-up   go-down


99. Ota M, Hartsuiker RJ, Haywood SL: The KEY to the ROCK: near-homophony in nonnative visual word recognition. Cognition; 2009 May;111(2):263-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To test the hypothesis that native language (L1) phonology can affect the lexical representations of nonnative words, a visual semantic-relatedness decision task in English was given to native speakers and nonnative speakers whose L1 was Japanese or Arabic.
  • In the critical conditions, the word pair contained a homophone or near-homophone of a semantically associated word, where a near-homophone was defined as a phonological neighbor involving a contrast absent in the speaker's L1 (e.g., ROCK-LOCK for native speakers of Japanese).
  • The results show that, even when auditory perception is not involved, recognition of nonnative words and, by implication, their lexical representations are affected by the L1 phonology.
  • [MeSH-minor] Analysis of Variance. Arabs. Auditory Perception / physiology. Decision Making. Female. Humans. Japan. Male. Psychomotor Performance / physiology. Reaction Time / physiology. Reading. Recognition (Psychology). Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19230869.001).
  • [ISSN] 1873-7838
  • [Journal-full-title] Cognition
  • [ISO-abbreviation] Cognition
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  •  go-up   go-down


100. Ojima S, Nakata H, Kakigi R: An ERP study of second language learning after childhood: effects of proficiency. J Cogn Neurosci; 2005 Aug;17(8):1212-28

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • One approach to address this issue is to compare the processes of second language (L2) learning after childhood and those of first language (L1) learning during childhood.
  • To study the cortical process of postchildhood L2 learning, we compared event-related brain potentials recorded from two groups of adult Japanese speakers who attained either high or intermediate proficiency in English after childhood (J-High and J-Low), and adult native English speakers (ENG).
  • Because early maturation and stability of semantic processing as opposed to syntactic processing are also a feature of L1 processing, postchildhood L2 learning may be governed by the same brain properties as those which govern childhood L1 learning.
  • [MeSH-minor] Adult. Data Interpretation, Statistical. Evoked Potentials / physiology. Female. Functional Laterality / physiology. Humans. Male. Psychomotor Performance / physiology. Semantics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16197679.001).
  • [ISSN] 0898-929X
  • [Journal-full-title] Journal of cognitive neuroscience
  • [ISO-abbreviation] J Cogn Neurosci
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  •  go-up   go-down






Advertisement