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1. Penny DJ, Vick GW 3rd: Novel therapies in childhood heart failure: today and tomorrow. Heart Fail Clin; 2010 Oct;6(4):591-621, x
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  • [Title] Novel therapies in childhood heart failure: today and tomorrow.
  • Heart failure is a growing problem, in both adult and pediatric populations, for which standard medical therapy, as of 2010, can have positive effects, but these are usually limited and progressively diminish with time in most patients.
  • Although there are many unique aspects to heart failure in patients with pediatric and congenital heart disease, many of the innovative approaches that are being developed for the care of adults with heart failure will be applicable to heart failure in childhood.
  • [MeSH-minor] Adrenergic beta-Antagonists / therapeutic use. Aptamers, Nucleotide / pharmacology. Aptamers, Peptide / pharmacology. Biomarkers / analysis. Cardiac Resynchronization Therapy. Cardiomyopathy, Dilated / therapy. Child. Diagnostic Imaging. Drug Design. Drug Discovery. Genetic Therapy. Heart-Assist Devices. Humans. Models, Biological. Nonlinear Dynamics. Proteins / chemistry. RNA Interference. Stem Cell Transplantation. Transplantation, Heterologous

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20869655.001).
  • [ISSN] 1551-7136
  • [Journal-full-title] Heart failure clinics
  • [ISO-abbreviation] Heart Fail Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adrenergic beta-Antagonists; 0 / Aptamers, Nucleotide; 0 / Aptamers, Peptide; 0 / Biomarkers; 0 / Proteins
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2. Chiolero A, Burnier M, Paradis G, Paccaud F, Bovet P: [Blood pressure measurement and screening of hypertension in children]. Rev Med Suisse; 2008 Sep 10;4(170):1904-6, 1908-9
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  • [Transliterated title] Mesure de la pression artérielle et dépistage de l'hypertension chez l'enfant.
  • However, due to the difficulties of obtaining a valid estimate of blood pressure, to the moderate tracking of blood pressure from childhood to adulthood, and the rarity of hypertension cases in childhood, the usefulness of systematic screening of hypertension during childhood is still controversial.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Blood Pressure Determination / methods. Child. Diastole. Humans. Mass Screening / methods. Middle Aged. Reference Values. Systole

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  • (PMID = 18847118.001).
  • [ISSN] 1660-9379
  • [Journal-full-title] Revue médicale suisse
  • [ISO-abbreviation] Rev Med Suisse
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
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3. Lynch T, Bialy L, Kellner JD, Osmond MH, Klassen TP, Durec T, Leicht R, Johnson DW: A systematic review on the diagnosis of pediatric bacterial pneumonia: when gold is bronze. PLoS One; 2010 Aug 06;5(8):e11989
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  • [Title] A systematic review on the diagnosis of pediatric bacterial pneumonia: when gold is bronze.
  • In North America, pneumonia is also a common source of childhood morbidity and occasionally mortality.
  • Numerous studies have shown that chest radiography findings lack precision in defining the etiology of childhood pneumonia.
  • 1) identify and categorize studies that have used single or multiple tests as a gold standard for assessing accuracy of other tests, and 2) given the 'gold standard' used, determine the accuracy of these other tests for diagnosing childhood bacterial pneumonia.
  • CONCLUSIONS: We have found that studies assessing the diagnostic accuracy of clinical, radiological, and laboratory tests for bacterial childhood pneumonia have used a heterogeneous group of gold standards, and found, at least in part because of this, that index tests have widely different accuracies.

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  • (PMID = 20700510.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] ENG
  • [Grant] Canada / Canadian Institutes of Health Research / / G118160601
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2917358
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4. Charakida M, Donald AE, Leary S, Halcox JP, Turner MW, Johnson M, Loukogeorgakis SP, Okorie MI, Davey Smith G, Deanfield JE, Klein NJ: Endothelial response to childhood infection: the role of mannose-binding lectin (MBL). Atherosclerosis; 2010 Jan;208(1):217-21
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  • [Title] Endothelial response to childhood infection: the role of mannose-binding lectin (MBL).
  • OBJECTIVE: To assess the influence of mannose-binding lectin (MBL) genotype on endothelial function in the presence and absence of infection in childhood.
  • Children were classified as AA (wild type) AO (heterozygotes) and OO (homozygotes).
  • CONCLUSION: Homozygosity for MBL variant alleles is associated with greater impairment in FMD during infection in childhood.
  • [MeSH-minor] Child. Female. Genotype. Humans. Male

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  • [Copyright] Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
  • [CommentIn] Atherosclerosis. 2010 Jan;208(1):32-3 [20003976.001]
  • (PMID = 19709662.001).
  • [ISSN] 1879-1484
  • [Journal-full-title] Atherosclerosis
  • [ISO-abbreviation] Atherosclerosis
  • [Language] eng
  • [Grant] United Kingdom / British Heart Foundation / / ; United Kingdom / Medical Research Council / / ; United Kingdom / Department of Health / / ; United Kingdom / Wellcome Trust / / ; United Kingdom / Medical Research Council / / G9815508
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Mannose-Binding Lectin
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5. Cehajic-Kapetanovic J, Kwartz J: Augmentin duo™ in the treatment of childhood blepharokeratoconjunctivitis. J Pediatr Ophthalmol Strabismus; 2010 Nov-Dec;47(6):356-60
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  • [Title] Augmentin duo™ in the treatment of childhood blepharokeratoconjunctivitis.
  • PURPOSE: To report the use of Augmentin Duo 400/57 (GlaxoSmithKline, Middlesex, UK) in the treatment of childhood blepharokeratoconjunctivitis (BKC).
  • [MeSH-minor] Adolescent. Child. Female. Follow-Up Studies. Humans. Male. Retrospective Studies. Treatment Outcome. Visual Acuity

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 20143765.001).
  • [ISSN] 1938-2405
  • [Journal-full-title] Journal of pediatric ophthalmology and strabismus
  • [ISO-abbreviation] J Pediatr Ophthalmol Strabismus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 74469-00-4 / Amoxicillin-Potassium Clavulanate Combination
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6. Shah DK, Guinane C, August P, Austin NC, Woodward LJ, Thompson DK, Warfield SK, Clemett R, Inder TE: Reduced occipital regional volumes at term predict impaired visual function in early childhood in very low birth weight infants. Invest Ophthalmol Vis Sci; 2006 Aug;47(8):3366-73
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  • [Title] Reduced occipital regional volumes at term predict impaired visual function in early childhood in very low birth weight infants.
  • [MeSH-minor] Child, Preschool. Female. Gestational Age. Humans. Infant, Newborn. Magnetic Resonance Imaging. Male. Saccades. Term Birth. Vision Disparity

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  • (PMID = 16877404.001).
  • [ISSN] 0146-0404
  • [Journal-full-title] Investigative ophthalmology & visual science
  • [ISO-abbreviation] Invest. Ophthalmol. Vis. Sci.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / P41 RR13218; United States / NIMH NIH HHS / MH / R21 MH67054
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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7. Sera Y, Kawaguchi H, Nakamura K, Sato T, Habara M, Okada S, Ishikawa N, Kojima S, Katoh O, Kobayashi M: A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia. Haematologica; 2005 Aug;90(8):1032-41
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  • [Title] A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia.
  • BACKGROUND AND OBJECTIVES: Cyclic neutropenia (CyN) in childhood and severe congenital neutropenia (SCN) are congenital disorders that cause chronic neutropenia.
  • [MeSH-minor] Child. Child, Preschool. DNA Primers. Exons. Female. Humans. Infant. Male. Mutation

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  • [CommentIn] Haematologica. 2005 Aug;90(8):1010A [16079089.001]
  • (PMID = 16079102.001).
  • [ISSN] 1592-8721
  • [Journal-full-title] Haematologica
  • [ISO-abbreviation] Haematologica
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / DNA Primers; EC 3.4.21.- / Serine Endopeptidases; EC 3.4.21.37 / Leukocyte Elastase; EC 3.4.21.71 / pancreatic elastase II
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8. Fowler T, Langley K, Rice F, van den Bree MB, Ross K, Wilkinson LS, Owen MJ, O'Donovan MC, Thapar A: Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity. Psychiatr Genet; 2009 Dec;19(6):312-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity.

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  • (PMID = 19829167.001).
  • [ISSN] 1473-5873
  • [Journal-full-title] Psychiatric genetics
  • [ISO-abbreviation] Psychiatr. Genet.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / / 059870; United Kingdom / Department of Health / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / SLC6A4 protein, human; 0 / Serotonin Plasma Membrane Transport Proteins; EC 1.4.3.4 / Monoamine Oxidase; EC 2.1.1.6 / Catechol O-Methyltransferase
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9. Borowitz SM, Cox DJ, Kovatchev B, Ritterband LM, Sheen J, Sutphen J: Treatment of childhood constipation by primary care physicians: efficacy and predictors of outcome. Pediatrics; 2005 Apr;115(4):873-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of childhood constipation by primary care physicians: efficacy and predictors of outcome.
  • OBJECTIVE: Childhood constipation accounts for 3% of visits to general pediatric clinics and as many as 30% of visits to pediatric gastroenterologists.
  • Little is known about how primary care physicians treat childhood constipation or the success of their treatments.
  • Parents completed daily diaries of their child's bowel habits for 2 weeks before starting treatment recommended by their primary care physician and again 2 months after treatment.
  • Treatment success corresponded to how aggressively the child was treated.
  • CONCLUSION: Primary care physicians tend to undertreat childhood constipation.
  • [MeSH-minor] Cathartics / administration & dosage. Child. Child, Preschool. Enema. Family Practice. Female. Humans. Male. Patient Compliance. Pediatrics

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  • (PMID = 15805358.001).
  • [ISSN] 1098-4275
  • [Journal-full-title] Pediatrics
  • [ISO-abbreviation] Pediatrics
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / R01 HD 28160
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cathartics
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10. Uneka CJ: Impact of home management of Plasmodium falciparum malaria on childhood malaria control in sub-Saharan Africa. Trop Biomed; 2009 Aug;26(2):182-99
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  • [Title] Impact of home management of Plasmodium falciparum malaria on childhood malaria control in sub-Saharan Africa.
  • In this report the impact of HMM in childhood malaria control in sub-Saharan Africa was reviewed using relevant publications identified through a Medline Entrez-Pubmed and Google search.
  • There was convincing evidence from the studies reviewed that HMM played a contributory role in reducing progress to severe malaria and overall childhood mortality.
  • [MeSH-minor] Africa South of the Sahara / epidemiology. Child, Preschool. Humans. Infant. Infant, Newborn. Medication Adherence. Patient Education as Topic. Treatment Outcome

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  • (PMID = 19901905.001).
  • [ISSN] 0127-5720
  • [Journal-full-title] Tropical biomedicine
  • [ISO-abbreviation] Trop Biomed
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
  • [Chemical-registry-number] 0 / Antimalarials
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11. Raj M, Kumar RK: Obesity in children & adolescents. Indian J Med Res; 2010 Nov;132:598-607
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  • Childhood obesity is a global phenomenon affecting all socio-economic groups, irrespective of age, sex or ethnicity.
  • Aetiopathogenesis of childhood obesity is multi-factorial and includes genetic, neuroendocrine, metabolic, psychological, environmental and socio-cultural factors.
  • Many co-morbid conditions like metabolic, cardiovascular, psychological, orthopaedic, neurological, hepatic, pulmonary and renal disorders are seen in association with childhood obesity.
  • A holistic approach to tackle the childhood obesity epidemic needs a collection of activities including influencing policy makers and legislation, mobilizing communities, restructuring organizational practices, establishing coalitions and networks, empowering providers, imparting community education as well as enriching and reinforcing individual awareness and skills.
  • [MeSH-minor] Adolescent. Child. Comorbidity. Humans. Risk Factors

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  • (PMID = 21150012.001).
  • [ISSN] 0971-5916
  • [Journal-full-title] The Indian journal of medical research
  • [ISO-abbreviation] Indian J. Med. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3028965
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12. Hobson-West P: 'Trusting blindly can be the biggest risk of all': organised resistance to childhood vaccination in the UK. Sociol Health Illn; 2007 Mar;29(2):198-215
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  • [Title] 'Trusting blindly can be the biggest risk of all': organised resistance to childhood vaccination in the UK.
  • [MeSH-minor] Child. Dissent and Disputes. Great Britain. Humans. Perception. Trust

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  • (PMID = 17381813.001).
  • [ISSN] 0141-9889
  • [Journal-full-title] Sociology of health & illness
  • [ISO-abbreviation] Sociol Health Illn
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Measles-Mumps-Rubella Vaccine
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13. Beesley AH, Rampellini JL, Palmer ML, Heng JY, Samuels AL, Firth MJ, Ford J, Kees UR: Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia. Mol Cancer; 2010;9:284
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  • [Title] Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia.
  • BACKGROUND: Rearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and resistance to glucocorticoids (GCs).
  • The absence of MLL-rearrangements suggested that this relationship represented expression of wild-type MLL.
  • RNAi knockdown of MLL expression in T-ALL cell lines significantly increased resistance to dexamethasone and gamma irradiation indicating an important role for wild-type MLL in the control of cellular apoptosis.
  • CONCLUSIONS: The data suggests that reduced expression of wild-type MLL can contribute to GC resistance in ALL patients both with and without MLL-translocations.
  • [MeSH-major] DNA Damage / genetics. Drug Resistance, Neoplasm / genetics. Glucocorticoids / pharmacology. Lymphocytes / drug effects. Myeloid-Lymphoid Leukemia Protein / metabolism. Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism

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  • (PMID = 20979663.001).
  • [ISSN] 1476-4598
  • [Journal-full-title] Molecular cancer
  • [ISO-abbreviation] Mol. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Glucocorticoids; 149025-06-9 / Myeloid-Lymphoid Leukemia Protein
  • [Other-IDs] NLM/ PMC2987983
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14. Wu J, Mo J, Huang CW, Peng LW, Xu L, Yang XC, Yu X: [Obesity and its influencing factors in primary school students from Kaifu District of Changsha City]. Zhongguo Dang Dai Er Ke Za Zhi; 2008 Apr;10(2):231-5
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  • The development of childhood obesity is associated with poor eating behaviors, less physical activity and increased television viewing time.
  • The control of childhood obesity may be beneficial to early prevention of some adult chronic diseases.
  • [MeSH-minor] Blood Glucose / analysis. Child. China / epidemiology. Cholesterol, LDL / blood. Female. Humans. Male. Multivariate Analysis. Prevalence. Waist-Hip Ratio

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  • (PMID = 18433555.001).
  • [ISSN] 1008-8830
  • [Journal-full-title] Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
  • [ISO-abbreviation] Zhongguo Dang Dai Er Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Cholesterol, LDL
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15. Weber MA, Ashworth MT, Sebire NJ: Portopulmonary hypertension in childhood presenting as sudden death. Pediatr Dev Pathol; 2006 Jan-Feb;9(1):65-71
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  • [Title] Portopulmonary hypertension in childhood presenting as sudden death.
  • Portopulmonary hypertension is a well-described and distinct clinical syndrome that is rare in childhood and is associated with a relatively poor prognosis.
  • [MeSH-minor] Child. Fatal Outcome. Humans. Male

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  • (PMID = 16808632.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Terry MB, Ferris JS, Tehranifar P, Wei Y, Flom JD: Birth weight, postnatal growth, and age at menarche. Am J Epidemiol; 2009 Jul 1;170(1):72-9
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  • Larger body size in childhood is correlated with earlier age at menarche; whether birth and infant body size changes are also associated with age at menarche is less clear.
  • This racially and ethnically diverse cohort (38% white, 40% African American, and 22% Puerto Rican) was used to investigate whether maternal (body size, pregnancy weight gain, age at menarche, smoking) and birth (birth weight, birth length, placental weight) variables and early infant body size changes were associated with age at menarche even after considering later childhood body size.
  • Higher percentile change in weight from ages 4 months to 1 year was associated with earlier age at menarche even after adjustment for later childhood growth (beta = -0.15, 95% confidence interval: -0.27, -0.02 years per 10-percentile change in weight from ages 4 months to 1 year).
  • These New York Women's Birth Cohort Adult Follow-up data (2001-2006) suggest that infant weight gain, in addition to childhood weight gain, may be associated with earlier age at menarche.

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  • (PMID = 19439580.001).
  • [ISSN] 1476-6256
  • [Journal-full-title] American journal of epidemiology
  • [ISO-abbreviation] Am. J. Epidemiol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / K07 CA090685; United States / NCI NIH HHS / CA / K07CA90685
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2733039
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17. Betts DR, Stanchescu R, Niggli FK, Cohen N, Rechavi G, Amariglio N, Trakhtenbrot L: SKY reveals a high frequency of unbalanced translocations involving chromosome 6 in t(12;21)-positive acute lymphoblastic leukemia. Leuk Res; 2008 Jan;32(1):39-43
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  • [Title] SKY reveals a high frequency of unbalanced translocations involving chromosome 6 in t(12;21)-positive acute lymphoblastic leukemia.
  • The G-band cryptic t(12;21)(p13;q22) is the most common chromosomal rearrangement in childhood acute lymphoblastic leukemia (ALL).
  • This study illustrates the value of a combined SKY and G-banding approach in identifying novel karyotypic events in childhood ALL.
  • [MeSH-major] Chromosomes, Human, Pair 12. Chromosomes, Human, Pair 21. Chromosomes, Human, Pair 6. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Spectral Karyotyping. Translocation, Genetic
  • [MeSH-minor] Child. Child, Preschool. Chromosome Aberrations. Chromosome Banding. Chromosome Deletion. Female. Humans. Male

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  • [CommentIn] Leuk Res. 2007 Dec;31(12):1761-2 [17560648.001]
  • (PMID = 17418891.001).
  • [ISSN] 0145-2126
  • [Journal-full-title] Leukemia research
  • [ISO-abbreviation] Leuk. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] England
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18. Murdoch M, Pryor JB, Polusny MA, Wall MM, Ripley DC, Gackstetter GD: The association between military sexual stress and psychiatric symptoms after controlling for other stressors. J Psychiatr Res; 2010 Dec;44(16):1129-36
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  • Besides sociodemographics, the strongest correlates of military sexual stress were working in an environment perceived to tolerate sexual harassment, reporting severer childhood maltreatment, and reporting more high-magnitude stressors.
  • Childhood maltreatment and other high-magnitude stressors acted as risk factors for and confounders of military sexual stress.

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  • [Copyright] Published by Elsevier Ltd.
  • (PMID = 21115147.001).
  • [ISSN] 1879-1379
  • [Journal-full-title] Journal of psychiatric research
  • [ISO-abbreviation] J Psychiatr Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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19. Nevels RM, Dehon EE, Alexander K, Gontkovsky ST: Psychopharmacology of aggression in children and adolescents with primary neuropsychiatric disorders: a review of current and potentially promising treatment options. Exp Clin Psychopharmacol; 2010 Apr;18(2):184-201
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  • Child and adolescent neuropsychiatric disorders associated with aggression include attention-deficit hyperactivity disorder, various mood disorders and in particular bipolar disorders/pediatric mania, schizophrenia, mental retardation, oppositional defiant disorder, conduct disorder, and autism spectrum disorders.
  • Studies reviewed in this article provide evidence for the use of psychostimulants, alpha-2 agonists, beta blockers, lithium, anticonvulsant mood-stabilizers, atypical antipsychotics, traditional antipsychotics, and selective serotonin reuptake inhibitors in treating pediatric aggression with the choice of medication dependent on symptomology.
  • Despite increased support for pediatric psychotropic use, there is a need for more long-term safety and efficacy studies of existing medications and newer, safer, and more effective agents with fewer side effects for the pharmacological treatment of all childhood disorders in which aggression is prominent.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Drug Costs. Drug Labeling. Female. Guidelines as Topic. Humans. Male

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  • [Copyright] 2010 APA, all rights reserved
  • (PMID = 20384430.001).
  • [ISSN] 1936-2293
  • [Journal-full-title] Experimental and clinical psychopharmacology
  • [ISO-abbreviation] Exp Clin Psychopharmacol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Psychotropic Drugs
  • [Number-of-references] 94
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20. Lifshitz F: Obesity in children. J Clin Res Pediatr Endocrinol; 2008;1(2):53-60
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  • The prevalence of childhood obesity has increased dramatically during the past decades all over the world.
  • The majority of obesity in adulthood has its origins in childhood which makes obesity a pediatric concern and the period when interventions should be done.
  • Obesity is associated with increased morbidity and mortality in adult life and several adverse consequences in childhood like insulin resistance, type 2 diabetes, dyslipidemia, polycystic ovarian syndrome, pulmonary and orthopedic disorders and psychological problems.
  • [MeSH-minor] Adult. Atherosclerosis. Child. Child Behavior. Female. Humans. Insulin Resistance. Intra-Abdominal Fat / physiopathology. Male. Weight Gain

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  • (PMID = 21318065.001).
  • [ISSN] 1308-5735
  • [Journal-full-title] Journal of clinical research in pediatric endocrinology
  • [ISO-abbreviation] J Clin Res Pediatr Endocrinol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Turkey
  • [Other-IDs] NLM/ PMC3005642
  • [Keywords] NOTNLM ; childhood / complications / incidence / obesity / prevention / treatment
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21. Willette AL: Where have all the parents gone? Do efforts to regulate food advertising to curb childhood obesity pass constitutional muster? J Leg Med; 2007 Oct-Dec;28(4):561-77
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  • [Title] Where have all the parents gone? Do efforts to regulate food advertising to curb childhood obesity pass constitutional muster?
  • [MeSH-minor] Child. Humans. Legislation, Food. Parents. United States

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  • (PMID = 18066979.001).
  • [ISSN] 0194-7648
  • [Journal-full-title] The Journal of legal medicine
  • [ISO-abbreviation] J Leg Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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22. Schrauder A, Reiter A, Gadner H, Niethammer D, Klingebiel T, Kremens B, Peters C, Ebell W, Zimmermann M, Niggli F, Ludwig WD, Riehm H, Welte K, Schrappe M: Superiority of allogeneic hematopoietic stem-cell transplantation compared with chemotherapy alone in high-risk childhood T-cell acute lymphoblastic leukemia: results from ALL-BFM 90 and 95. J Clin Oncol; 2006 Dec 20;24(36):5742-9
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  • [Title] Superiority of allogeneic hematopoietic stem-cell transplantation compared with chemotherapy alone in high-risk childhood T-cell acute lymphoblastic leukemia: results from ALL-BFM 90 and 95.
  • PURPOSE: The role of hematopoietic stem-cell transplantation (SCT) in first complete remission (CR1) for children with very high-risk (VHR) acute lymphoblastic leukemia (ALL) is still under critical discussion.
  • CONCLUSION: SCT in CR1 is superior to treatment with chemotherapy alone for childhood HR-T-ALL.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Hematopoietic Stem Cell Transplantation. Leukemia-Lymphoma, Adult T-Cell / drug therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Disease-Free Survival. Female. Histocompatibility Testing. Humans. Infant. Infant, Newborn. Male. Risk Factors. Transplantation, Homologous


23. Lee JT, Son JY, Cho YS: Benefits of mitigated ambient air quality due to transportation control on childhood asthma hospitalization during the 2002 summer Asian games in Busan, Korea. J Air Waste Manag Assoc; 2007 Aug;57(8):968-73
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  • [Title] Benefits of mitigated ambient air quality due to transportation control on childhood asthma hospitalization during the 2002 summer Asian games in Busan, Korea.
  • Relative risks of hospitalization for childhood asthma during the post-Asian Game period compared with the baseline period were estimated using a time-series analysis of the generalized additive Poisson model.
  • [MeSH-minor] Child. Humans. Korea / epidemiology. Seasons. Time Factors. Weather


24. Grigoriadis S, Gomori JM, Grigoriadis N, Cohen JE: Clinically successful late recanalization of basilar artery occlusion in childhood: what are the odds? Case report and review of the literature. J Neurol Sci; 2007 Sep 15;260(1-2):256-60
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  • [Title] Clinically successful late recanalization of basilar artery occlusion in childhood: what are the odds? Case report and review of the literature.
  • BACKGROUND AND PURPOSE: Acute basilar artery occlusion is an infrequent but potentially fatal cause of stroke, both in adults and children.
  • We present our experience with a 6-year-old child and we investigate the rationality for late treatment of acute basilar occlusion in children.
  • METHODS: We report the case of a 6-year-old boy with acute basilar artery occlusion presented with a full blown locked-in syndrome, admitted to the endovascular suite 44 h after the stroke onset, and we review all the reported cases of basilar artery occlusions presented with locked-in syndrome in children.
  • CONCLUSIONS: To our knowledge, this is the first report of complete clinical recovery after delayed (50 h) endovascular recanalization of basilar artery in a child.
  • Intra-arterial thrombolysis combined with cerebral angioplasty, can successfully restore the patency of the basilar artery and the neurologic deficit of children with acute basilar artery occlusion, even after a considerable delay.
  • [MeSH-minor] Age Factors. Anticoagulants / administration & dosage. Child. Heparin / administration & dosage. Humans. Male. Pons / blood supply. Pons / pathology. Pons / physiopathology. Quadriplegia / etiology. Quadriplegia / pathology. Quadriplegia / therapy. Time Factors. Treatment Outcome. Urokinase-Type Plasminogen Activator / administration & dosage

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  • (PMID = 17482211.001).
  • [ISSN] 0022-510X
  • [Journal-full-title] Journal of the neurological sciences
  • [ISO-abbreviation] J. Neurol. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anticoagulants; 9005-49-6 / Heparin; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator
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25. Laurence S, Peterken R, Burns C: Fresh Kids: the efficacy of a Health Promoting Schools approach to increasing consumption of fruit and water in Australia. Health Promot Int; 2007 Sep;22(3):218-26
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  • The Fresh Kids programme utilized the Health Promoting Schools (HPSs) framework to design a whole-of-school, multifaceted intervention targeting specific behaviours to promote healthy eating and reduce the risk factors associated with childhood obesity.
  • Targeting key nutrition behaviours and using the HPS framework is an effective and simple approach which could be readily implemented in similar childhood settings.
  • [MeSH-minor] Child. Community-Institutional Relations. Cross-Sectional Studies. Dietetics. Health Behavior. Humans. Obesity / epidemiology. Obesity / prevention & control. Program Development. Vegetables. Victoria / epidemiology

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  • (PMID = 17584783.001).
  • [ISSN] 0957-4824
  • [Journal-full-title] Health promotion international
  • [ISO-abbreviation] Health Promot Int
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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26. Papadia C, Naves LA, Costa SS, Vaz JA, Domingues L, Casulari LA: Incidence of obesity does not appear to be increased after treatment of acute lymphoblastic leukemia in Brazilian children: role of leptin, insulin, and IGF-1. Horm Res; 2007;68(4):164-70
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  • [Title] Incidence of obesity does not appear to be increased after treatment of acute lymphoblastic leukemia in Brazilian children: role of leptin, insulin, and IGF-1.
  • BACKGROUND/AIMS: It has been reported that children treated for acute lymphoblastic leukemia (ALL) in developed countries show an increased risk of overweight and obesity in adolescence and adulthood.
  • METHODS: Two groups of subjects were studied: 27 survivors of childhood ALL (14.0 +/- 4.2 years old; post-treatment interval 8.6 +/- 3.9 years) (ALL group) and 17 healthy subjects (12.8 +/- 4 years old) (control group) selected on the basis of their kinship with the patients.
  • CONCLUSION: The data indicate the presence of alterations in the homeostatic regulatory mechanisms controlling body weight in Brazilian patients treated for ALL in childhood, still, it did not lead to obesity in the absence of favorable environmental conditions.
  • [MeSH-major] Insulin / physiology. Insulin-Like Growth Factor I / physiology. Leptin / physiology. Obesity / epidemiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / epidemiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • [MeSH-minor] Adolescent. Body Mass Index. Brazil. Child. Female. Follow-Up Studies. Humans. Incidence. Male. Waist-Hip Ratio


27. Appel IM, den Boer ML, Meijerink JP, Veerman AJ, Reniers NC, Pieters R: Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia. Blood; 2006 Jun 1;107(11):4244-9
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  • [Title] Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia.
  • L-asparaginase (L-Asp) is an effective drug for treatment of children with acute lymphoblastic leukemia (ALL).
  • No significant difference of AS mRNA up-regulation was found between precursor B- and T-ALL or between hyperdiploids, TEL/AML1 rearranged ALL or absence of genetic abnormalities.
  • [MeSH-major] Asparaginase / pharmacology. Aspartate-Ammonia Ligase / genetics. Polyethylene Glycols / pharmacology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Up-Regulation / drug effects
  • [MeSH-minor] Adolescent. Antineoplastic Agents / pharmacology. Antineoplastic Agents / therapeutic use. Child. Child, Preschool. Female. Humans. Infant. Leukemia-Lymphoma, Adult T-Cell / drug therapy. Leukemia-Lymphoma, Adult T-Cell / pathology. Male. Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / pathology. RNA, Neoplasm / analysis. RNA, Neoplasm / drug effects. Treatment Outcome

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  • (PMID = 16497975.001).
  • [ISSN] 0006-4971
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / RNA, Neoplasm; 0 / pegaspargase; 30IQX730WE / Polyethylene Glycols; EC 3.5.1.1 / Asparaginase; EC 6.3.1.1 / Aspartate-Ammonia Ligase
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28. Povlsen L, Ringsberg KC: Learning to live with type 1 diabetes from the perspective of young non-western immigrants in Denmark. J Clin Nurs; 2008 Nov;17(11c):300-9
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  • [Title] Learning to live with type 1 diabetes from the perspective of young non-western immigrants in Denmark.
  • AIMS AND OBJECTIVES: To explore how young adults with a non-western immigrant background and type 1 diabetes since childhood/adolescence have perceived learning to live with the disease, with special focus on health education and support.
  • Special attention should be paid to the fact that immigrants may have limited pre-knowledge of chronic diseases in childhood, including the concept of selfcare.
  • [MeSH-major] Adaptation, Psychological. Diabetes Mellitus, Type 1 / psychology. Diabetes Mellitus, Type 1 / therapy. Emigrants and Immigrants / psychology. Ethnic Groups / psychology
  • [MeSH-minor] Adolescent. Adult. Child. Denmark. Female. Health Education. Humans. Learning. Male. Parents. Self Care. Self Concept. Young Adult

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  • [Copyright] © 2008 The Authors. Journal compilation © 2008 Blackwell Publishing Ltd.
  • (PMID = 26327413.001).
  • [ISSN] 1365-2702
  • [Journal-full-title] Journal of clinical nursing
  • [ISO-abbreviation] J Clin Nurs
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; adaptation / diabetes care / health education / support / type 1 diabetes / young non‐western immigrants
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29. Bjerg A, Rönmark E: Asthma in school age: prevalence and risk factors by time and by age. Clin Respir J; 2008 Oct;2 Suppl 1:123-6
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  • BACKGROUND: Childhood is the most important age for asthma development.
  • METHODS: In 1996, all children in grade 1-2 (age 7-8) in three cities in Northern Sweden were invited to an expanded International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire.
  • [MeSH-minor] Age Distribution. Child. Family Health. Female. Humans. Male. Prevalence. Remission, Spontaneous. Risk Factors. Sweden / epidemiology


30. Stromme P, Kanavin OJ, Abdelnoor M, Woldseth B, Rootwelt T, Diderichsen J, Bjurulf B, Sommer F, Magnus P: Incidence rates of progressive childhood encephalopathy in Oslo, Norway: a population based study. BMC Pediatr; 2007;7:25
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  • [Title] Incidence rates of progressive childhood encephalopathy in Oslo, Norway: a population based study.
  • [MeSH-minor] Adolescent. Age Distribution. Child. Child, Preschool. Disease Progression. Female. Humans. Incidence. Infant. Infant, Newborn. Male. Norway / epidemiology. Retrospective Studies. Risk Factors. Sex Distribution

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  • (PMID = 17597517.001).
  • [ISSN] 1471-2431
  • [Journal-full-title] BMC pediatrics
  • [ISO-abbreviation] BMC Pediatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1914055
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31. Nowicki M, Ostalska-Nowicka D, Kaczmarek E, Miskowiak B, Witt M: Vascular endothelial growth factor C--a potent risk factor in childhood acute lymphoblastic leukaemia: an immunocytochemical approach. Histopathology; 2006 Aug;49(2):170-7
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  • [Title] Vascular endothelial growth factor C--a potent risk factor in childhood acute lymphoblastic leukaemia: an immunocytochemical approach.
  • AIMS: To investigate the immunocytochemical expression of vascular endothelial growth factor C (VEGF-C) and its receptors (VEGFR-2 and VEGFR-3) in childhood acute lymphoblastic leukaemia (ALL) blasts and to determine the possible role of this complex in the pathogenesis and prognosis of ALL.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology. Vascular Endothelial Growth Factor C / blood
  • [MeSH-minor] Adolescent. Bone Marrow Cells / chemistry. Bone Marrow Cells / pathology. Bone Marrow Transplantation. Child. Child, Preschool. Humans. Immunohistochemistry. Prognosis. Risk Factors. Treatment Outcome. Vascular Endothelial Growth Factor Receptor-2 / blood. Vascular Endothelial Growth Factor Receptor-3 / blood

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  • (PMID = 16879394.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor C; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-3
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32. Naithani R, Mahapatra M, Dutta P, Kumar R, Pati HP, Choudhry VP: Paroxysmal nocturnal hemoglobinuria in childhood and adolescence--a retrospective analysis of 18 cases. Indian J Pediatr; 2008 Jun;75(6):575-8
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  • [Title] Paroxysmal nocturnal hemoglobinuria in childhood and adolescence--a retrospective analysis of 18 cases.
  • [MeSH-minor] Adolescent. Child. Female. Humans. Male. Retrospective Studies. Sex Factors. Survival Rate. Thrombosis / complications. Treatment Outcome


33. Tanaka M, Olsen RW, Medina MT, Schwartz E, Alonso ME, Duron RM, Castro-Ortega R, Martinez-Juarez IE, Pascual-Castroviejo I, Machado-Salas J, Silva R, Bailey JN, Bai D, Ochoa A, Jara-Prado A, Pineda G, Macdonald RL, Delgado-Escueta AV: Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy. Am J Hum Genet; 2008 Jun;82(6):1249-61
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  • [Title] Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy.
  • Childhood absence epilepsy (CAE) accounts for 10% to 12% of epilepsy in children under 16 years of age.

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  • (PMID = 18514161.001).
  • [ISSN] 1537-6605
  • [Journal-full-title] American journal of human genetics
  • [ISO-abbreviation] Am. J. Hum. Genet.
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / P01 NS035985; United States / NINDS NIH HHS / NS / R01 NS055057; United States / NINDS NIH HHS / NS / NS35985
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Complementary; 0 / GABRB3 protein, human; 0 / Receptors, GABA-A; 56-12-2 / gamma-Aminobutyric Acid
  • [Other-IDs] NLM/ PMC2427288
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34. Sourander A, Helstelä L: Childhood predictors of externalizing and internalizing problems in adolescence. A prospective follow-up study from age 8 to 16. Eur Child Adolesc Psychiatry; 2005 Dec;14(8):415-23
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  • [Title] Childhood predictors of externalizing and internalizing problems in adolescence. A prospective follow-up study from age 8 to 16.
  • The aim of this study was to assess the childhood predictors of externalizing and internalizing symptoms in adolescence in an epidemiological sample.
  • At age 8, children were evaluated with parental and teacher Rutter scales, and with the Child Depression Inventory (CDI), and at age 16 with the Child Behavior Checklist.
  • The study supports the findings from earlier studies showing that the stability of behavior problems from childhood to adolescence is substantial.
  • [MeSH-minor] Adolescent. Child. Data Collection / methods. Faculty. Family. Female. Finland / epidemiology. Follow-Up Studies. Forecasting. Humans. Male. Mental Disorders / epidemiology. Prospective Studies. Psychophysiologic Disorders / epidemiology

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  • (PMID = 16341497.001).
  • [ISSN] 1018-8827
  • [Journal-full-title] European child & adolescent psychiatry
  • [ISO-abbreviation] Eur Child Adolesc Psychiatry
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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35. Verrotti A, Parisi P, Loiacono G, Mohn A, Grosso S, Balestri P, Tozzi E, Iannetti P, Chiarelli F, Curatolo P: Levetiracetam monotherapy for childhood occipital epilepsy of gastaut. Acta Neurol Scand; 2009 Nov;120(5):342-6
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  • [Title] Levetiracetam monotherapy for childhood occipital epilepsy of gastaut.
  • OBJECTIVES: The aim of this open label pilot study was to evaluate the efficacy and tolerability of levetiracetam (LEV) as 'de novo' monotherapy in children and adolescents with late onset childhood occipital epilepsy-Gastaut type (COE-G).
  • [MeSH-minor] Adolescent. Anticonvulsants / administration & dosage. Child. Drug Administration Schedule. Electroencephalography. Female. Follow-Up Studies. Humans. Male. Patient Selection. Pilot Projects. Prospective Studies. Seizures / drug therapy. Treatment Outcome

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  • (PMID = 19754870.001).
  • [ISSN] 1600-0404
  • [Journal-full-title] Acta neurologica Scandinavica
  • [ISO-abbreviation] Acta Neurol. Scand.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Multicenter Study
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Anticonvulsants; 230447L0GL / etiracetam; ZH516LNZ10 / Piracetam
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36. Chathurvedi D, Khadgawat R, Kulshrestha B, Gupta N, Joseph AA, Diwedi S, Ammini AC: Type 2 diabetes increases risk for obesity among subsequent generations. Diabetes Technol Ther; 2009 Jun;11(6):393-8
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  • [Title] Type 2 diabetes increases risk for obesity among subsequent generations.
  • BACKGROUND: Childhood obesity is increasing worldwide.
  • STUDY DESIGN: Children and adolescents attending our pediatric and adolescent endocrine clinic with the main complaint of overweight or obesity were included in this study.
  • [MeSH-major] Diabetes Mellitus, Type 2 / complications. Obesity / epidemiology
  • [MeSH-minor] Adolescent. Body Composition. Body Mass Index. Child. Fathers. Female. Humans. India / epidemiology. Lipids / blood. Male. Mothers. Overweight / epidemiology. Overweight / genetics


37. Kwan ML, Buffler PA, Wiemels JL, Metayer C, Selvin S, Ducore JM, Block G: Breastfeeding patterns and risk of childhood acute lymphoblastic leukaemia. Br J Cancer; 2005 Aug 8;93(3):379-84
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  • [Title] Breastfeeding patterns and risk of childhood acute lymphoblastic leukaemia.
  • The risk of childhood acute lymphoblastic leukaemia (ALL) was investigated in relation to breastfeeding patterns in the Northern California Childhood Leukaemia Study.
  • Data collected by self-administered and in-person questionnaires from biological mothers of leukaemia cases (age 0-14 years) in the period 1995-2002 were matched to birth certificate controls on date of birth, sex, Hispanic ethnic status, and maternal race.
  • Complimentary feeding characteristics such as type of milk/formula used and age started eating solid foods among breastfed children were not associated with ALL risk.
  • This study provides no evidence that breastfeeding affects the occurrence of childhood ALL.

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  • (PMID = 16052219.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] ENG
  • [Grant] United States / NIEHS NIH HHS / ES / P42 ES004705; United States / NIEHS NIH HHS / ES / R01 ES009137; United States / NCHHSTP CDC HHS / PS / PS42 ES04705; United States / NIEHS NIH HHS / ES / R01 ES09137
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2361562
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38. Slopen N, Williams DR, Seedat S, Moomal H, Herman A, Stein DJ: Adversities in childhood and adult psychopathology in the South Africa Stress and Health Study: associations with first-onset DSM-IV disorders. Soc Sci Med; 2010 Nov;71(10):1847-54
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  • [Title] Adversities in childhood and adult psychopathology in the South Africa Stress and Health Study: associations with first-onset DSM-IV disorders.
  • Extensive epidemiologic research from the United States demonstrates that childhood adversities (CAs) are predictive of several psychiatric outcomes, including depression, anxiety, substance abuse, and externalizing disorders.
  • The best-fitting model for first onset of any disorder included separate indicators for each type of CA, in addition to indicator variables for the number of other CAs reported.

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
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  • (PMID = 20870332.001).
  • [ISSN] 1873-5347
  • [Journal-full-title] Social science & medicine (1982)
  • [ISO-abbreviation] Soc Sci Med
  • [Language] ENG
  • [Grant] United States / NIDA NIH HHS / DA / R01 DA016558; United States / FIC NIH HHS / TW / R03 TW006481; United States / NIMH NIH HHS / MH / R01 MH069864; United States / NIMH NIH HHS / MH / R01MH070884; United States / NIMH NIH HHS / MH / R01-MH069864; United States / FIC NIH HHS / TW / R03-TW006481; United States / NIMH NIH HHS / MH / R13-MH066849; United States / NIMH NIH HHS / MH / HHSN271200700030C; United States / NIMH NIH HHS / MH / R01 MH070884; United States / NIMH NIH HHS / MH / R13 MH066849
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS235578; NLM/ PMC2967595
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39. Steer AC, Tikoduadua LV, Manalac EM, Colquhoun S, Carapetis JR, Maclennan C: Validation of an Integrated Management of Childhood Illness algorithm for managing common skin conditions in Fiji. Bull World Health Organ; 2009 Mar;87(3):173-9
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  • [Title] Validation of an Integrated Management of Childhood Illness algorithm for managing common skin conditions in Fiji.
  • OBJECTIVE: To assess the sensitivity of an Integrated Management of Childhood Illness (IMCI) algorithm to detect common skin conditions in children in Fiji.
  • Every child was assessed by a nurse trained in the use of the IMCI algorithm and also an expert paediatrician.
  • FINDINGS: High sensitivity for identifying skin problems (sensitivity: 98.7%; 95% confidence interval, CI: 95.5-99.9) was found for the algorithm applied by IMCI-trained nurses, who were able to identify the one child with a severe skin infection and all three children with periorbital cellulitis.
  • [MeSH-minor] Child, Preschool. Female. Fiji. Humans. Infant. Male

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  • (PMID = 19377712.001).
  • [ISSN] 1564-0604
  • [Journal-full-title] Bulletin of the World Health Organization
  • [ISO-abbreviation] Bull. World Health Organ.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC2654647
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40. Moorman AV, Raimondi SC, Pui CH, Baruchel A, Biondi A, Carroll AJ, Forestier E, Gaynon PS, Harbott J, Harms DO, Heerema N, Pieters R, Schrappe M, Silverman LB, Vilmer E, Harrison CJ, Ponte di Legno Working Group: No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities. Leukemia; 2005 Apr;19(4):557-63
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  • [Title] No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities.
  • This study characterized the additional chromosomal abnormalities (ACA) associated with 11q23 rearrangements in 450 infants and children with acute lymphoblastic leukemia (ALL) and examined the impact of these ACA on survival.
  • This study has conclusively demonstrated that there is no prognostic effect of secondary chromosomal changes in association with 11q23 abnormalities in childhood ALL.
  • [MeSH-major] Chromosome Aberrations. Chromosomes, Human, Pair 11. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • [MeSH-minor] Child. Child, Preschool. Cohort Studies. Disease-Free Survival. Female. Humans. Incidence. Infant. Male. Prognosis

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  • (PMID = 15744345.001).
  • [ISSN] 0887-6924
  • [Journal-full-title] Leukemia
  • [ISO-abbreviation] Leukemia
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA21765; United States / NCI NIH HHS / CA / CA36401; United States / NCI NIH HHS / CA / CA51001; United States / NCI NIH HHS / CA / CA60419; United States / NCI NIH HHS / CA / CA78224; United States / NIGMS NIH HHS / GM / GM61393
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
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41. Taplin CE, Craig ME, Lloyd M, Taylor C, Crock P, Silink M, Howard NJ: The rising incidence of childhood type 1 diabetes in New South Wales, 1990-2002. Med J Aust; 2005 Sep 5;183(5):243-6
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  • [Title] The rising incidence of childhood type 1 diabetes in New South Wales, 1990-2002.
  • OBJECTIVES: To determine the incidence of childhood type 1 diabetes mellitus (T1DM) in New South Wales from 1997 to 2002; to compare with previously published rates (1990-1996); and to analyse trends in incidence from 1990 to 2002.
  • Childhood population data were obtained from the Australian Bureau of Statistics.
  • CONCLUSIONS: The incidence of childhood-onset T1DM has increased significantly in all age groups in NSW since 1990.
  • Resource planning in the management of childhood diabetes in NSW should take these findings into account.
  • [MeSH-major] Diabetes Mellitus, Type 1 / epidemiology
  • [MeSH-minor] Adolescent. Age Distribution. Child. Child, Preschool. Female. Humans. Incidence. Infant. Infant, Newborn. Male. New South Wales / epidemiology. Sex Distribution

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  • (PMID = 16138797.001).
  • [ISSN] 0025-729X
  • [Journal-full-title] The Medical journal of Australia
  • [ISO-abbreviation] Med. J. Aust.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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42. Camfield CS, Camfield PR: Juvenile myoclonic epilepsy 25 years after seizure onset: a population-based study. Neurology; 2009 Sep 29;73(13):1041-5
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  • RESULTS: Twenty-four patients (17 women) had JME, 3.5% of all childhood-onset epilepsy.
  • Ten women had > or =1 pregnancy and 4 men fathered a child.
  • [MeSH-minor] Adult. Age of Onset. Child. Cohort Studies. Disease Progression. Family Health. Female. Follow-Up Studies. Humans. Male. Pregnancy. Social Behavior

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  • [SummaryForPatientsIn] Neurology. 2009 Sep 29;73(13):e64-7 [19786691.001]
  • (PMID = 19786695.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants
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43. O'Callaghan FV, Al Mamun A, O'Callaghan M, Clavarino A, Williams GM, Bor W, Heussler H, Najman JM: The link between sleep problems in infancy and early childhood and attention problems at 5 and 14 years: Evidence from a birth cohort study. Early Hum Dev; 2010 Jul;86(7):419-24
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  • [Title] The link between sleep problems in infancy and early childhood and attention problems at 5 and 14 years: Evidence from a birth cohort study.
  • AIMS: To examine whether sleep problems in infancy and early childhood are independently related to attention difficulty at 5 and 14 years, and to the continuity of attention difficulties from 5 to 14 years.
  • SUBJECTS: 7223 women who delivered a live, singleton child between 1981 and 1983 were recruited at the first antenatal visit.
  • OUTCOME MEASURES: Attention problems were assessed with items from the Child Behaviour Checklist (CBCL) and were classified as adolescent onset (i.e. problems at 14 but not at 5); early remitter (problems at 5, no problem at 14); and persistent (i.e. at both 5 and 14).
  • CONCLUSIONS: Sleep problems in early childhood are an indicator of subsequent attention problems that may persist into adolescence.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Infant. Male. Prospective Studies. Risk Factors. Sex Factors

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  • [Copyright] 2010. Published by Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20646881.001).
  • [ISSN] 1872-6232
  • [Journal-full-title] Early human development
  • [ISO-abbreviation] Early Hum. Dev.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
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44. Loh AH, Chui CH: Port-A-Cath insertions in acute leukaemia and childhood malignancies. Asian J Surg; 2007 Jul;30(3):193-9
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  • [Title] Port-A-Cath insertions in acute leukaemia and childhood malignancies.
  • Incidence of catheter-related bloodstream infections (CRBSIs), other complications and CRBSI-related port removals were analysed for cases with acute leukaemia versus other malignancies.
  • While mean preoperative platelet count was 125.34 x 10(9)/L in children with acute leukaemia and 392.11 x 10(9)/L in those with other malignancies (p < 0.01), the incidence of all complications were similar between both subgroups.

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  • (PMID = 17638639.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] China
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45. Camfield C, Camfield P: Preventable and unpreventable causes of childhood-onset epilepsy plus mental retardation. Pediatrics; 2007 Jul;120(1):e52-5
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  • [Title] Preventable and unpreventable causes of childhood-onset epilepsy plus mental retardation.
  • OBJECTIVE: The objective of this study was to determine the causes of childhood epilepsy associated with mental retardation and determine whether these causes are preventable.
  • METHODS: We selected all patients from the Nova Scotia population-based childhood epilepsy cohort (n = 692) who had mental retardation and had epilepsy onset between 1977 and 1985.
  • RESULTS: Overall, 147 patients had mental retardation and epilepsy (21% of all childhood epilepsy).
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Infant. Male


46. Zafeiriou DI, Ververi A, Vargiami E: Childhood autism and associated comorbidities. Brain Dev; 2007 Jun;29(5):257-72
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  • [Title] Childhood autism and associated comorbidities.
  • This review refers to all the genetic syndromes that have been described in children with pervasive developmental disorders (tuberous sclerosis, fragile X, Down, neurofibromatosis, Angelman, Prader-Willi, Gilles de la Tourette, Williams, etc.).

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  • (PMID = 17084999.001).
  • [ISSN] 0387-7604
  • [Journal-full-title] Brain & development
  • [ISO-abbreviation] Brain Dev.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 243
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47. Kurkcuoglu IC, Eroglu A, Karaoglanoglu N, Turkyilmaz A, Tekinbas C, Basoglu A: Surgical approach of pulmonary hydatidosis in childhood. Int J Clin Pract; 2005 Feb;59(2):168-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical approach of pulmonary hydatidosis in childhood.
  • [MeSH-minor] Adolescent. Chest Pain / parasitology. Child. Child, Preschool. Cough / pathology. Echinococcosis, Hepatic / complications. Female. Humans. Male. Rupture, Spontaneous. Tomography, X-Ray Computed / methods

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  • (PMID = 15854192.001).
  • [ISSN] 1368-5031
  • [Journal-full-title] International journal of clinical practice
  • [ISO-abbreviation] Int. J. Clin. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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48. Moschonis G, Tanagra S, Vandorou A, Kyriakou AE, Dede V, Siatitsa PE, Koumpitski A, Androutsos O, Grammatikaki E, Kantilafti M, Naoumi A, Farmaki AE, Siopi A, Papadopoulou EZ, Voutsadaki E, Chlouveraki F, Maragkopoulou K, Argyri E, Giannopoulou A, Manios Y: Social, economic and demographic correlates of overweight and obesity in primary-school children: preliminary data from the Healthy Growth Study. Public Health Nutr; 2010 Oct;13(10A):1693-700
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  • Several socio-economic and demographic data and the child's 'popularity' score were also recorded with specifically designed standardized questionnaires.
  • Annual family income of € 12,000-20,000 (OR = 1·58), residence ownership (OR = 1·63) and the grandmother as the child's primary caregiver (OR = 1·38) were significantly associated with higher odds of childhood overweight and obesity.
  • The grandmother as the child's primary caregiver and an annual family income of € 12,000-20,000 remained significantly associated with childhood overweight and obesity after adding all significant correlates of childhood overweight and obesity observed at the bivariate level in a multivariate regression model (OR = 1·51 and 1·61, respectively).
  • CONCLUSIONS: Among family income, residence ownership, child's primary caregiver, parental nationality and popularity scores that were identified as significant correlates of childhood overweight and obesity at the bivariate level, lower family income and grandmother as the child's primary caregiver were the only factors that remained significantly associated with childhood overweight and obesity at a multivariate level.
  • [MeSH-major] Child Rearing. Income. Obesity / epidemiology. Overweight / epidemiology. Social Class. Social Environment
  • [MeSH-minor] Adolescent. Child. Female. Greece / epidemiology. Humans. Male. Risk Factors

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  • (PMID = 20883568.001).
  • [ISSN] 1475-2727
  • [Journal-full-title] Public health nutrition
  • [ISO-abbreviation] Public Health Nutr
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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49. Bose K Jr, Mandal GC: Proposed new anthropometric indices of childhood undernutrition. Malays J Nutr; 2010 Apr;16(1):131-6
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  • [Title] Proposed new anthropometric indices of childhood undernutrition.
  • The three conventional anthropometric indicators of childhood undernutrition are stunting (low height-for-age), underweight (low weight-for-age) and wasting (low weight-for-height).
  • Recently a new composite index, namely the Composite Index of Anthropometric Failure (CIAF) has been proposed and utilised to study childhood undernutrition.

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  • (PMID = 22691860.001).
  • [ISSN] 1394-035X
  • [Journal-full-title] Malaysian journal of nutrition
  • [ISO-abbreviation] Malays J Nutr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
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50. Hamelin C, Salomon C, Sitta R, Gueguen A, Cyr D, Lert F: Childhood sexual abuse and adult binge drinking among Kanak women in New Caledonia. Soc Sci Med; 2009 Apr;68(7):1247-53
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  • [Title] Childhood sexual abuse and adult binge drinking among Kanak women in New Caledonia.
  • Using data from the first population study on violence against women and their consequences on health in New Caledonia, South Pacific, this article investigates the association between childhood sexual abuse and binge drinking among 441 adult Kanak women.
  • Childhood sexual abuse before 15 years of age was reported by 11.6% of respondents.
  • After controlling for social and demographic factors, an independent association was found between childhood sexual abuse and current binge drinking.
  • This study is the first to analyse the contribution of childhood sexual abuse to the likelihood of later heavy alcohol use in an indigenous population in the South Pacific.
  • [MeSH-major] Child Abuse, Sexual / ethnology. Ethanol / poisoning

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  • (PMID = 19217196.001).
  • [ISSN] 0277-9536
  • [Journal-full-title] Social science & medicine (1982)
  • [ISO-abbreviation] Soc Sci Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 3K9958V90M / Ethanol
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51. Karlsson H, Ahlborg B, Dalman C, Hemmingsson T: Association between erythrocyte sedimentation rate and IQ in Swedish males aged 18-20. Brain Behav Immun; 2010 Aug;24(6):868-73
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  • Data on cardiovascular risk factors measured at conscription and national register data on childhood circumstances at age 10 were considered as potential sources of confounding.
  • While an association was observed across IQ bands and ESR ranges, independent of cardiovascular risk factors or childhood circumstances, the association was slightly attenuated by adjustment for childhood socioeconomic position (SEP).
  • An association between childhood SEP and ESR was detected that remained after adjusting for IQ.
  • The ESR was also associated with future mortality following adjustment for childhood SEP.
  • [MeSH-minor] Adolescent. Adult. Blood Pressure / physiology. Body Height. Child. Data Interpretation, Statistical. Hematocrit. Humans. Life Style. Linear Models. Male. Mortality. Smoking / epidemiology. Socioeconomic Factors. Sweden. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • [CommentIn] Brain Behav Immun. 2010 Aug;24(6):866-7 [20417705.001]
  • (PMID = 20226851.001).
  • [ISSN] 1090-2139
  • [Journal-full-title] Brain, behavior, and immunity
  • [ISO-abbreviation] Brain Behav. Immun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Dellava JE, Thornton LM, Hamer RM, Strober M, Plotnicov K, Klump KL, Brandt H, Crawford S, Fichter MM, Halmi KA, Jones I, Johnson C, Kaplan AS, Lavia M, Mitchell J, Rotondo A, Treasure J, Woodside DB, Berrettini WH, Kaye WH, Bulik CM: Childhood anxiety associated with low BMI in women with anorexia nervosa. Behav Res Ther; 2010 Jan;48(1):60-7
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  • [Title] Childhood anxiety associated with low BMI in women with anorexia nervosa.
  • The present study explores childhood personality characteristics that could be associated with the ability to attain an extremely low BMI.
  • METHODS: Participants were 326 women from the Genetics of Anorexia Nervosa (GAN) Study who completed the Structured Interview for Anorexia Nervosa and Bulimic Syndromes and whose mother completed the Child Behavioral Checklist and/or Revised Dimensions of Temperament Survey.
  • Path analysis in the GAN and a validation sample, Price Foundation Anorexia Nervosa Trios Study, confirmed the relation between early childhood anxiety, caloric restriction, qualitative food item restriction, excessive exercise, and low BMI.
  • Path analysis also confirmed a relation between childhood anxiety and caloric restriction, which mediated the relation between childhood anxiety and low BMI in the GAN sample only.
  • CONCLUSION: Fearful or anxious behavior as a child was associated with the attainment of low BMI in AN and childhood anxiety was associated with caloric restriction.
  • Measures of anxiety and factors associated with anxiety-proneness in childhood may index children at risk for restrictive behaviors and extremely low BMIs in AN.

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  • [Copyright] Copyright 2009 Elsevier Ltd. All rights reserved.
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  • (PMID = 19822312.001).
  • [ISSN] 1873-622X
  • [Journal-full-title] Behaviour research and therapy
  • [ISO-abbreviation] Behav Res Ther
  • [Language] ENG
  • [Grant] United States / NIMH NIH HHS / MH / MH066117-01; United States / NIMH NIH HHS / MH / T32 MH076694-01A1; United States / NIMH NIH HHS / MH / T32MH076694-03; United States / NIMH NIH HHS / MH / T32 MH076694; United States / NIMH NIH HHS / MH / R01 MH066117; United States / NIMH NIH HHS / MH / R01 MH066117-01; United States / NIMH NIH HHS / MH / MH66117
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS152380; NLM/ PMC2812624
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53. Asipu D, Jaffray B: Treatment of severe childhood constipation with restorative proctocolectomy. Arch Dis Child; 2010 Nov;95(11):867-70
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  • [Title] Treatment of severe childhood constipation with restorative proctocolectomy.
  • CONCLUSIONS: In highly selected cases, restorative proctocolectomy may allow resolution of the symptoms of severe constipation and avoid leaving a child with a permanent stoma.
  • [MeSH-minor] Child. Chronic Disease. Defecation. Female. Humans. Male. Psychometrics. Quality of Life. Treatment Outcome

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  • [CommentIn] Arch Dis Child. 2010 Nov;95(11):859-60 [20530142.001]
  • [CommentIn] Arch Dis Child. 2010 Nov;95(11):861-2 [20930012.001]
  • (PMID = 20371582.001).
  • [ISSN] 1468-2044
  • [Journal-full-title] Archives of disease in childhood
  • [ISO-abbreviation] Arch. Dis. Child.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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54. Wilsnack SC, Hughes TL, Johnson TP, Bostwick WB, Szalacha LA, Benson P, Aranda F, Kinnison KE: Drinking and drinking-related problems among heterosexual and sexual minority women. J Stud Alcohol Drugs; 2008 Jan;69(1):129-39
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  • Exclusively heterosexual women also reported less childhood sexual abuse, early alcohol use, and depression.
  • Higher rates of childhood sexual abuse, early drinking, and depression among sexual minority women suggest that these experiences may be important in assessing and treating problems related to their drinking, and in developing prevention and early intervention strategies.

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  • (PMID = 18080073.001).
  • [ISSN] 1937-1888
  • [Journal-full-title] Journal of studies on alcohol and drugs
  • [ISO-abbreviation] J Stud Alcohol Drugs
  • [Language] ENG
  • [Grant] United States / NIAAA NIH HHS / AA / R01 AA004610-26; United States / NIDA NIH HHS / DA / T32 DA07267; United States / NIAAA NIH HHS / AA / R01 AA13328; United States / NIAAA NIH HHS / AA / R01 AA004610; United States / NIAAA NIH HHS / AA / K01 AA00266; United States / NIDA NIH HHS / DA / T32 DA07293; United States / NIAAA NIH HHS / AA / R01 AA013328
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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55. Chartier MJ, Walker JR, Naimark B: Separate and cumulative effects of adverse childhood experiences in predicting adult health and health care utilization. Child Abuse Negl; 2010 Jun;34(6):454-64
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  • [Title] Separate and cumulative effects of adverse childhood experiences in predicting adult health and health care utilization.
  • (1) to examine the relative contribution of childhood abuse and other adverse childhood experiences to poor adult health and increased health care utilization and (2) to examine the cumulative effects of adverse childhood experiences on adult health and health care utilization.
  • Adverse childhood experiences examined were childhood physical and sexual abuse, parental marital conflict, poor parent-child relationship, low parental education and parental psychopathology.
  • RESULTS: Most (72%) respondents reported at least one adverse childhood experience and a considerable proportion of respondents (37%) reported two or more of these experiences.
  • In examining the bivariate models, childhood physical and sexual abuse had a stronger influence than other types of adverse childhood experiences.
  • With the addition of other adverse childhood experiences in the model, the odds ratios for childhood abuse were attenuated but remained statistically significant for most health outcomes.
  • This suggests that childhood abuse may have a unique adverse influence on the development of poor adult health.
  • When an aggregate variable was created to explore the cumulative effects of adverse childhood experience, the odds were increased, with each additional experience, for reporting multiple health problems [odds ratio (OR): 1.22], poor self-rated health (OR: 1.18), pain (OR: 1.24), disability (OR: 1.24), general practitioner use (OR: 1.12), emergency room use (OR: 1.29) and health professional use (OR: 1.19).
  • CONCLUSIONS: This study suggests that childhood abuse and other adverse childhood experiences are overlapping risk factors for long-term adult health problems and that the accumulation of these adverse experiences increases the risk of poor adult health.
  • PRACTICE IMPLICATIONS: This study highlights the importance of the many adverse childhood experiences influencing long-term health.
  • In practice, childhood abuse is often difficult to identify as families tend to keep it hidden and reported cases represent only a small percentage of the actual cases.
  • Assessments and interventions which focus on improving socio-economic status, strengthening marital and parent-child relationships, and supporting parents with mental health issues are less threatening for families than assessing their experiences with abuse and neglect and are more likely to be effective in identifying and supporting at-risk families.
  • [MeSH-major] Adult Survivors of Child Abuse / psychology. Family Conflict. Health Services / utilization
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child, Preschool. Female. Forecasting. Health Status. Health Surveys. Humans. Logistic Models. Male. Middle Aged. Ontario. Risk Factors. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20409586.001).
  • [ISSN] 1873-7757
  • [Journal-full-title] Child abuse & neglect
  • [ISO-abbreviation] Child Abuse Negl
  • [Language] eng
  • [Grant] Canada / Canadian Institutes of Health Research / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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56. Bandyopadhyay S, Mukherjee K, Chatterjee M, Bhattacharya DK, Mandal C: Detection of immune-complexed 9-O-acetylated sialoglycoconjugates in the sera of patients with pediatric acute lymphoblastic leukemia. J Immunol Methods; 2005 Feb;297(1-2):13-26
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  • [Title] Detection of immune-complexed 9-O-acetylated sialoglycoconjugates in the sera of patients with pediatric acute lymphoblastic leukemia.
  • Although childhood acute lymphoblastic leukemia (ALL) is highly responsive to chemotherapy, reliable techniques are needed to determine treatment outcome.
  • [MeSH-major] Antigens, Tumor-Associated, Carbohydrate / blood. Glycoconjugates / blood. Immunoblotting / methods. Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis. Sialic Acids / blood
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Histocompatibility Antigens Class II / blood. Humans. Lectins / blood. Lectins / immunology. Male. Prognosis. Treatment Outcome

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  • (PMID = 15777927.001).
  • [ISSN] 0022-1759
  • [Journal-full-title] Journal of immunological methods
  • [ISO-abbreviation] J. Immunol. Methods
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / Glycoconjugates; 0 / Histocompatibility Antigens Class II; 0 / Lectins; 0 / Sialic Acids; 0 / achatinin(H)
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57. Muraro A, Roberts G, Clark A, Eigenmann PA, Halken S, Lack G, Moneret-Vautrin A, Niggemann B, Rancé F, EAACI Task Force on Anaphylaxis in Children: The management of anaphylaxis in childhood: position paper of the European academy of allergology and clinical immunology. Allergy; 2007 Aug;62(8):857-71
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  • [Title] The management of anaphylaxis in childhood: position paper of the European academy of allergology and clinical immunology.
  • This position paper prepared by the EAACI Taskforce on Anaphylaxis in Children aims to provide practical guidelines for managing anaphylaxis in childhood based on the limited evidence available.
  • A tailored anaphylaxis management plan is needed, based on an individual risk assessment, which is influenced by the child's previous allergic reactions, other medical conditions and social circumstances.
  • [MeSH-minor] Adolescent. Adrenal Cortex Hormones / therapeutic use. Child. Child, Preschool. Europe. Histamine H1 Antagonists / therapeutic use. Humans. Infant

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  • (PMID = 17590200.001).
  • [ISSN] 0105-4538
  • [Journal-full-title] Allergy
  • [ISO-abbreviation] Allergy
  • [Language] eng
  • [Publication-type] Journal Article; Practice Guideline
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Bronchodilator Agents; 0 / Histamine H1 Antagonists; YKH834O4BH / Epinephrine
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58. Stepanova I, Nevsimalova S, Hanusova J: Rhythmic movement disorder in sleep persisting into childhood and adulthood. Sleep; 2005 Jul;28(7):851-7
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  • [Title] Rhythmic movement disorder in sleep persisting into childhood and adulthood.
  • STUDY OBJECTIVES: To evaluate the type, duration, and distribution of rhythmic movements in sleep stages in school-aged children and young adults; to find out if cases of rhythmic movement disorder persisting beyond infancy are associated with any daytime symptoms or psychopathology.
  • [MeSH-minor] Adolescent. Adult. Attention Deficit Disorder with Hyperactivity / diagnosis. Attention Deficit Disorder with Hyperactivity / epidemiology. Child. Electroencephalography. Female. Humans. Male. Neurologic Examination. Polysomnography. Psychological Tests. Sleep / physiology

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  • (PMID = 16124665.001).
  • [ISSN] 0161-8105
  • [Journal-full-title] Sleep
  • [ISO-abbreviation] Sleep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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59. Briggs-Gowan MJ, Carter AS: Social-emotional screening status in early childhood predicts elementary school outcomes. Pediatrics; 2008 May;121(5):957-62
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  • [Title] Social-emotional screening status in early childhood predicts elementary school outcomes.
  • When children were 12 to 36 months of age (mean age: 23.8 months; SD: 7.1 months), parents completed the Brief Infant-Toddler Social and Emotional Assessment and questions concerning their level of worry about their child's behavior, emotions, and social development.
  • When children were in early elementary school (mean age: 6.0 years; SD: 0.4 years), parents completed the Child Behavior Checklist and teachers completed the Teacher Report Form regarding behavioral problems.
  • In a subsample (n = 389), parents reported child psychiatric status.
  • In multivariate analyses that included Brief Infant-Toddler Social and Emotional Assessment status and parental worry, Brief Infant-Toddler Social and Emotional Assessment scores significantly predicted all school-age problems, whereas worry predicted only parent reports with the Child Behavior Checklist.
  • CONCLUSIONS: Screening with a standardized tool in early childhood has the potential to identify the majority of children who exhibit significant emotional/behavioral problems in early elementary school.

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  • (PMID = 18450899.001).
  • [ISSN] 1098-4275
  • [Journal-full-title] Pediatrics
  • [ISO-abbreviation] Pediatrics
  • [Language] ENG
  • [Grant] United States / NIMH NIH HHS / MH / R01 MH066645-04; United States / NIMH NIH HHS / MH / R01 MH055278; United States / NIMH NIH HHS / MH / MH066645-03; United States / NIMH NIH HHS / MH / MH066645-01; United States / NIMH NIH HHS / MH / MH066645-02; United States / NIMH NIH HHS / MH / R01MH66645; United States / NIMH NIH HHS / MH / R01 MH066645-05; United States / NIMH NIH HHS / MH / R01MH55278; United States / NIMH NIH HHS / MH / MH066645-05; United States / NIMH NIH HHS / MH / R01 MH066645-06; United States / NIMH NIH HHS / MH / R01 MH066645-02; United States / NIMH NIH HHS / MH / MH066645-06; United States / NIMH NIH HHS / MH / R01 MH066645; United States / NIMH NIH HHS / MH / R01 MH066645-03; United States / NIMH NIH HHS / MH / MH066645-04; United States / NIMH NIH HHS / MH / R01 MH066645-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS259631; NLM/ PMC3088107
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60. Kidas E, Möricke A, Beier R, Welte K, Schrappe M, Stanulla M, Grigull L: Genetic polymorphisms of the lymphotoxin alpha gene are associated with increased risk for lethal infections during induction therapy for childhood acute leukemia: a case-control study. Int J Hematol; 2009 Jun;89(5):584-91
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  • [Title] Genetic polymorphisms of the lymphotoxin alpha gene are associated with increased risk for lethal infections during induction therapy for childhood acute leukemia: a case-control study.
  • This study aimed at correlating these polymorphisms to lethal infections during childhood acute lymphoblastic leukemia (ALL).
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Infection / genetics. Polymorphism, Genetic. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • [MeSH-minor] Child. Child, Preschool. Female. Humans. Infant. Lymphotoxin-alpha / genetics. Male. Risk

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  • (PMID = 19353239.001).
  • [ISSN] 1865-3774
  • [Journal-full-title] International journal of hematology
  • [ISO-abbreviation] Int. J. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Lymphotoxin-alpha
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61. Lob-Corzilius T: Overweight and obesity in childhood--a special challenge for public health. Int J Hyg Environ Health; 2007 Oct;210(5):585-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Overweight and obesity in childhood--a special challenge for public health.
  • [MeSH-minor] Child. Child Behavior / physiology. Environment. Exercise / physiology. Humans. Overnutrition. Social Environment

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  • (PMID = 17889606.001).
  • [ISSN] 1438-4639
  • [Journal-full-title] International journal of hygiene and environmental health
  • [ISO-abbreviation] Int J Hyg Environ Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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62. Manganoni AM, Farisoglio C, Tucci G, Facchetti F, Ungari M, Calzavara-Pinton PG: Thin primary cutaneous melanoma in childhood and adolescence: report of 12 cases. Pediatr Dermatol; 2009 May-Jun;26(3):356-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thin primary cutaneous melanoma in childhood and adolescence: report of 12 cases.
  • From our case studies it was found that the clinical characteristics detected in melanomas diagnosed in childhood and adolescence have been the same as those described in adults and that the ABCDE clinical criteria may be helpful basics of melanoma.
  • [MeSH-minor] Adolescent. Child. Female. Humans. Male

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  • (PMID = 19706109.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Brunetti L, Francavilla R, Leonardo Miniello V, Leone M, Rana M, Colazzo D, Logrillo P, Favoino B, Armenio L: Influence of HLA antigens and OSAS in childhood: a preliminary report. J Sleep Res; 2005 Jun;14(2):157-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Influence of HLA antigens and OSAS in childhood: a preliminary report.
  • [MeSH-minor] Child. Child, Preschool. Female. Gene Frequency / genetics. Genetic Predisposition to Disease / genetics. Genetics, Population. Humans. Infant. Italy. Male. Odds Ratio. Polymerase Chain Reaction. Snoring / genetics

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  • (PMID = 15910513.001).
  • [ISSN] 0962-1105
  • [Journal-full-title] Journal of sleep research
  • [ISO-abbreviation] J Sleep Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Histocompatibility Antigens Class I
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64. Laursen B, Nielsen JW: Influence of sociodemographic factors on the risk of unintentional childhood home injuries. Eur J Public Health; 2008 Aug;18(4):366-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Influence of sociodemographic factors on the risk of unintentional childhood home injuries.
  • BACKGROUND: While social differences in childhood injuries are recognized, less is known about how social and demographic differences relate to injury mechanism.
  • The information was linked to data including parents' education and income and family type, and the results were compared with those for a random sample of the population.
  • CONCLUSION: Childhood injury incidence depended on sociodemographic factors.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Denmark / epidemiology. Female. Humans. Infant. Infant, Newborn. Male. Risk Factors. Socioeconomic Factors

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  • (PMID = 18515863.001).
  • [ISSN] 1464-360X
  • [Journal-full-title] European journal of public health
  • [ISO-abbreviation] Eur J Public Health
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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65. Levine KA: Against all odds: resilience in single mothers of children with disabilities. Soc Work Health Care; 2009;48(4):402-19
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There is a substantial body of literature that explores family adaptation within the context of childhood disability.
  • Study participants consisted of 15 single mothers who had previously participated in the "Family Strengths and Childhood Disability" research project.
  • Findings revealed a marked contrast between public discourses about single motherhood and childhood disability and the personal narratives of the mothers in this study.
  • [MeSH-minor] Adaptation, Psychological. Adolescent. Adult. Child. Cohort Studies. Female. Humans. Interviews as Topic. Male. Middle Aged. Social Support. Young Adult

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  • (PMID = 19396709.001).
  • [ISSN] 0098-1389
  • [Journal-full-title] Social work in health care
  • [ISO-abbreviation] Soc Work Health Care
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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66. Pearce MS, Deary IJ, Young AH, Parker L: Childhood IQ and deaths up to middle age: The Newcastle Thousand Families Study. Public Health; 2006 Nov;120(11):1020-6
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  • [Title] Childhood IQ and deaths up to middle age: The Newcastle Thousand Families Study.
  • OBJECTIVES: To test the hypothesis that an association exists between childhood IQ (at age 11) and mortality up to middle age.
  • RESULTS: Childhood IQ was significantly related to mortality in men (hazard ratio 0.57 for a standard deviation change in IQ at age 11; 95% CI 0.37, 0.86; P=0.007), but not in women (hazard ratio 0.79; 95% CI 0.49, 1.27; P=0.33).
  • CONCLUSIONS: These results confirm a recently reported association between individual differences in childhood cognition and mortality up to middle age, independent of childhood socio-economic circumstances.
  • [MeSH-major] Cognition / classification. Intelligence / classification. Mortality / trends. Psychology, Child
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Child. Cohort Studies. Educational Measurement. England / epidemiology. Female. Humans. Intelligence Tests. Language. Male. Mathematics. Middle Aged. Proportional Hazards Models. Risk Assessment. Sex Distribution. Social Class

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  • (PMID = 16935314.001).
  • [ISSN] 0033-3506
  • [Journal-full-title] Public health
  • [ISO-abbreviation] Public Health
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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67. Maecker B, Mougiakakos D, Zimmermann M, Behrens M, Hollander S, Schrauder A, Schrappe M, Welte K, Klein C: Dendritic cell deficiencies in pediatric acute lymphoblastic leukemia patients. Leukemia; 2006 Apr;20(4):645-9
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  • [Title] Dendritic cell deficiencies in pediatric acute lymphoblastic leukemia patients.
  • Acute lymphoblastic leukemia (ALL) cells are particularly poor at generating anti-leukemia immunity, despite residing in lymphoid organs.
  • To assess a potential role of dendritic cells (DC) in poor anti-leukemia immunity, we analyzed peripheral blood DC in 55 pediatric ALL patients at the time of initial diagnosis and 19 age-matched healthy controls.
  • Thus, depletion of DC in B-lineage ALL patients may contribute to poor anti-leukemia immune responses.
  • [MeSH-major] Antigens, CD11c / biosynthesis. Dendritic Cells / immunology. Lectins, C-Type / biosynthesis. Membrane Glycoproteins / biosynthesis. Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology. Receptors, Immunologic / biosynthesis
  • [MeSH-minor] Adolescent. Antigens, CD / biosynthesis. Antigens, CD13 / biosynthesis. Antigens, Differentiation, Myelomonocytic / biosynthesis. B-Lymphocytes / immunology. B-Lymphocytes / pathology. Cell Count. Child. Child, Preschool. Cohort Studies. Female. Flow Cytometry / methods. Humans. Immunophenotyping. Leukocyte Count. Male. Monocytes / pathology. Neutrophils / pathology. Peroxidase / biosynthesis. Sensitivity and Specificity. Sialic Acid Binding Ig-like Lectin 3

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  • (PMID = 16498391.001).
  • [ISSN] 0887-6924
  • [Journal-full-title] Leukemia
  • [ISO-abbreviation] Leukemia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD11c; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD33 protein, human; 0 / CLEC4C protein, human; 0 / Lectins, C-Type; 0 / Membrane Glycoproteins; 0 / Receptors, Immunologic; 0 / Sialic Acid Binding Ig-like Lectin 3; EC 1.11.1.7 / Peroxidase; EC 3.4.11.2 / Antigens, CD13
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68. Crosnoe R, Leventhal T, Wirth RJ, Pierce KM, Pianta RC, NICHD Early Child Care Research Network: Family socioeconomic status and consistent environmental stimulation in early childhood. Child Dev; 2010 May-Jun;81(3):972-87
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  • [Title] Family socioeconomic status and consistent environmental stimulation in early childhood.
  • This study applied growth curve modeling to a sample of 1,364 American children, followed from birth through age 6, who had been categorized by their exposure to cognitive stimulation at home and in preschool child care and 1st-grade classrooms.
  • Net of socioeconomic selection into different settings, children had higher math achievement when they were consistently stimulated in all 3, and they had higher reading achievement when consistently stimulated at home and in child care.

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  • [Cites] Child Dev. 2001 Sep-Oct;72(5):1534-53 [11699686.001]
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  • [ISSN] 1467-8624
  • [Journal-full-title] Child development
  • [ISO-abbreviation] Child Dev
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / U10 HD025460-18; United States / NICHD NIH HHS / HD / U10 HD025456-18; United States / NICHD NIH HHS / HD / R01 HD055359-01A1; None / None / / U10 HD025449-18; United States / NICHD NIH HHS / HD / U10 HD025451-19; United States / NICHD NIH HHS / HD / U10 HD025447; United States / NICHD NIH HHS / HD / R01 HD055359; United States / NICHD NIH HHS / HD / U10 HD025455-18; United States / NICHD NIH HHS / HD / U10 HD025449-18; United States / NICHD NIH HHS / HD / U10 HD025420-19; United States / NICHD NIH HHS / HD / U10 HD027040-18; United States / NICHD NIH HHS / HD / U10 HD025449; United States / NICHD NIH HHS / HD / U10 HD025447-18; United States / NICHD NIH HHS / HD / U10 HD025445; United States / NICHD NIH HHS / HD / U10 HD025445-19
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS190595; NLM/ PMC2892811
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69. DeMattia L, Lemont L, Meurer L: Do interventions to limit sedentary behaviours change behaviour and reduce childhood obesity? A critical review of the literature. Obes Rev; 2007 Jan;8(1):69-81
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  • [Title] Do interventions to limit sedentary behaviours change behaviour and reduce childhood obesity? A critical review of the literature.
  • [MeSH-major] Child Behavior. Exercise / physiology. Health Promotion / methods. Obesity / epidemiology. Obesity / prevention & control
  • [MeSH-minor] Child. Clinical Trials as Topic. Female. Humans. Life Style. Male. Risk Factors


70. Dennis LK, Vanbeek MJ, Beane Freeman LE, Smith BJ, Dawson DV, Coughlin JA: Sunburns and risk of cutaneous melanoma: does age matter? A comprehensive meta-analysis. Ann Epidemiol; 2008 Aug;18(8):614-27
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  • PURPOSE: Sunburns are an important risk factor for melanoma and those occurring in childhood are often cited as posing the greatest risk.
  • We conducted a meta-analysis to quantify the magnitude of association for melanoma and sunburns during childhood, adolescence, adulthood and over a lifetime.
  • RESULTS: An increased risk of melanoma was seen with increasing number of sunburns for all time-periods (childhood, adolescence, adulthood, and lifetime).
  • CONCLUSIONS: Overall, these results show an increased risk of melanoma with increasing number of sunburns during all life-periods, not just childhood.

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  • (PMID = 18652979.001).
  • [ISSN] 1873-2585
  • [Journal-full-title] Annals of epidemiology
  • [ISO-abbreviation] Ann Epidemiol
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA088834-01; United States / NCI NIH HHS / CA / R03 CA088834; United States / NCI NIH HHS / CA / CA88834-01; United States / NCI NIH HHS / CA / R03 CA088834-01
  • [Publication-type] Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS64271; NLM/ PMC2873840
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71. Wingenfeld K, Spitzer C, Mensebach C, Grabe HJ, Hill A, Gast U, Schlosser N, Höpp H, Beblo T, Driessen M: [The German version of the Childhood Trauma Questionnaire (CTQ): preliminary psychometric properties]. Psychother Psychosom Med Psychol; 2010 Nov;60(11):442-50
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  • [Title] [The German version of the Childhood Trauma Questionnaire (CTQ): preliminary psychometric properties].
  • [Transliterated title] Die deutsche Version des Childhood Trauma Questionnaire (CTQ): Erste Befunde zu den psychometrischen Kennwerten.
  • Given the relevance of child maltreatment for the development and treatment of many mental disorders, the objective of our study was the psychometric evaluation of the German version of the Childhood Trauma Questionnaire (CTQ).
  • The psychometric properties of the German version of the CTQ were similar to the American original; it proved to be a reliable and valid screen for the retrospective assessment of child maltreatment.
  • [MeSH-major] Adult Survivors of Child Abuse / psychology. Child Abuse / psychology. Child Abuse, Sexual / psychology
  • [MeSH-minor] Adult. Checklist. Child. Dissociative Disorders / psychology. Factor Analysis, Statistical. Female. Germany. Humans. Language. Male. Psychometrics. Reproducibility of Results. Stress Disorders, Post-Traumatic / psychology. Surveys and Questionnaires

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  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 20200804.001).
  • [ISSN] 0937-2032
  • [Journal-full-title] Psychotherapie, Psychosomatik, medizinische Psychologie
  • [ISO-abbreviation] Psychother Psychosom Med Psychol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Validation Studies
  • [Publication-country] Germany
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72. Cortez MA, Scrideli CA, Yunes JA, Valera ET, Toledo SR, Pavoni-Ferreira PC, Lee ML, Petrilli AS, Brandalise SR, Tone LG: mRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death. Pediatr Blood Cancer; 2009 Dec;53(6):996-1004
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  • [Title] mRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death.
  • BACKGROUND: Increased activity of multidrug resistance (MDR) genes has been associated with treatment failure in acute leukemias, although with controversial reports.
  • The objective of the present study was to assess the expression profile of the genes related to MDR: ABCB1, ABCC1, ABCC3, ABCG2, and LRP/MVP in terms of the clinical and biological variable and the survival of children with acute lymphoblastic leukemia (ALL).
  • CONCLUSION: The present data suggest a low participation of the drug efflux genes in treatment failure in patients with childhood ALL.
  • [MeSH-major] ATP-Binding Cassette Transporters / genetics. Genes, MDR / genetics. Multidrug Resistance-Associated Proteins / genetics. Neoplasm Proteins / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] ATP Binding Cassette Transporter, Sub-Family G, Member 2. Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / toxicity. Child. Child, Preschool. Gene Expression Profiling. Humans. Infant. RNA, Messenger / analysis. Risk Assessment. Survival Analysis. Survival Rate. Treatment Failure

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  • (PMID = 19672972.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ABCG2 protein, human; 0 / ATP Binding Cassette Transporter, Sub-Family G, Member 2; 0 / ATP-Binding Cassette Transporters; 0 / Multidrug Resistance-Associated Proteins; 0 / Neoplasm Proteins; 0 / RNA, Messenger; Y49M64GZ4Q / multidrug resistance-associated protein 1
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73. Unal S, Cetin M, Tuncer AM, Gümrük F, Yetgin S: The prognostic impact of myeloid antigen expression in pediatric acute lymphoblastic leukemia patients. Turk J Pediatr; 2008 Nov-Dec;50(6):533-6
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  • [Title] The prognostic impact of myeloid antigen expression in pediatric acute lymphoblastic leukemia patients.
  • The incidence of mixed-lineage leukemias in the pediatric age group was previously reported as 13.8% for myeloid antigen-positive ALL and 11.1% for lymphoid antigen-positive acute myeloid leukemia (AML).
  • Our study also supports most of the previous data and we postulate that myeloid antigen expression in pediatric ALL cases has insignificant effect on clinical presentation, relapse rates and survival.
  • [MeSH-major] Antigens, CD / immunology. Antigens, Differentiation, Myelomonocytic / immunology. Antigens, Neoplasm / immunology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Flow Cytometry. Humans. Immunophenotyping. Male. Prognosis. Retrospective Studies. Survival Rate

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  • (PMID = 19227415.001).
  • [ISSN] 0041-4301
  • [Journal-full-title] The Turkish journal of pediatrics
  • [ISO-abbreviation] Turk. J. Pediatr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Antigens, Neoplasm
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74. Licinio J: The experience of bipolar disorder: a personal perspective on the impact of mood disorder symptoms. Mol Psychiatry; 2005 Sep;10(9):827-30
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  • For some diseases like acute lymphoblastic leukemia (ALL) of childhood, rates of remission and cure have been constantly advancing through better use of existing compounds.


75. Goldsby RE, Liu Q, Nathan PC, Bowers DC, Yeaton-Massey A, Raber SH, Hill D, Armstrong GT, Yasui Y, Zeltzer L, Robison LL, Packer RJ: Late-occurring neurologic sequelae in adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. J Clin Oncol; 2010 Jan 10;28(2):324-31
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  • [Title] Late-occurring neurologic sequelae in adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study.
  • PURPOSE: Children with acute lymphoblastic leukemia (ALL) are often cured, but the therapies they receive may be neurotoxic.
  • PATIENTS AND METHODS: We analyzed adverse neurologic outcomes that occurred after diagnosis in 4,151 adult survivors of childhood ALL who participated in the Childhood Cancer Survivor Study (CCSS), a retrospective cohort of 5-year survivors of childhood cancer diagnosed between 1970 and 1986.

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  • (PMID = 19917844.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U24 CA055727; United States / NCI NIH HHS / CA / U24 CA55727
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2815720
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76. Kalina T, Vaskova M, Mejstrikova E, Madzo J, Trka J, Stary J, Hrusak O: Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens. BMC Cancer; 2005;5:38
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  • [Title] Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens.
  • BACKGROUND: Aberrant expression of myeloid antigens (MyAgs) on acute lymphoblastic leukemia (ALL) cells is a well-documented phenomenon, although its regulating mechanisms are unclear.
  • METHODS: In a cohort of 365 consecutively diagnosed Czech B-precursor ALL patients, we analyze distribution of MyAg+ cases and mutual relationship among CD13, CD15, CD33, CD65 and CD66c.
  • We report no prognostic significance of CD66c, globally or separately in genotype subsets of B-precursor ALL, nor an association with known risk factors (n = 254).
  • CONCLUSION: In contrast to general notion we show that different MyAgs in lymphoblastic leukemia represent different biological circumstances.
  • [MeSH-major] Antigens, CD / biosynthesis. Cell Adhesion Molecules / biosynthesis. Gene Expression Regulation, Neoplastic. Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism
  • [MeSH-minor] Adolescent. Antigens, CD13 / biosynthesis. Antigens, CD15 / biosynthesis. Antigens, Differentiation, Myelomonocytic / biosynthesis. Blotting, Western. Cell Membrane / metabolism. Child. Child, Preschool. Cohort Studies. Cytoplasm / metabolism. Czech Republic. Disease-Free Survival. Flow Cytometry. GPI-Linked Proteins. Genotype. Glycosylation. Humans. Immunophenotyping. Infant. Prognosis. RNA / metabolism. Recurrence. Reverse Transcriptase Polymerase Chain Reaction. Sialic Acid Binding Ig-like Lectin 3. Time Factors. Transcription, Genetic

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  • (PMID = 15826304.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD15; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD33 protein, human; 0 / CD65s antigen, human; 0 / CEACAM6 protein, human; 0 / Cell Adhesion Molecules; 0 / GPI-Linked Proteins; 0 / Sialic Acid Binding Ig-like Lectin 3; 63231-63-0 / RNA; EC 3.4.11.2 / Antigens, CD13
  • [Other-IDs] NLM/ PMC1112585
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77. Petridou ET, Dessypris N, Panagopoulou P, Sergentanis TN, Mentis AF, Pourtsidis A, Polychronopoulou S, Kalmanti M, Athanasiadou-Piperopoulou F, Moschovi M: Adipocytokines in relation to Hodgkin lymphoma in children. Pediatr Blood Cancer; 2010 Feb;54(2):311-5
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  • This case-control study aims to explore the association of serum adiponectin/leptin with childhood Hodgkin lymphoma (HL).
  • Study participants were 75 children with histologically confirmed HL, registered in the Nationwide Registry for Childhood Haematological Malignancies and 75 age- and gender-matched controls.
  • In conclusion, elevated serum adiponectin might be a risk factor for childhood HL.
  • [MeSH-minor] Adolescent. Case-Control Studies. Child. Child, Preschool. Female. Greece / epidemiology. Humans. Infant. Infant, Newborn. Logistic Models. Male. Multivariate Analysis. Risk Factors

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19856392.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adiponectin; 0 / Leptin
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78. Paravastu R: Paraplegia of late onset in adolescents with healed childhood caries of dorsal spine: A cause of pressure on the cord and treatment. Indian J Orthop; 2008 Oct;42(4):454-9
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  • [Title] Paraplegia of late onset in adolescents with healed childhood caries of dorsal spine: A cause of pressure on the cord and treatment.
  • Internal salient at the level of acute kyphotic deformity of the dorsal spine is formed by posterior cartilaginous remains of grossly destroyed vertebral bodies.
  • MATERIALS AND METHODS: Eight adolescent patients mean age 14.4 yrs 6 males and 2 females with healed childhood caries of dorsal spine, having a mean kyphotic angle of 80 degrees (range 60 degrees -140 degrees ) presented with paraplegia of late onset.
  • CONCLUSION: In adolescents with healed caries of dorsal spine with acute kyphosis and paraplegia, the treatment of choice is anterior surgical decompression of the cord and bridging the gap thus created with bone graft.

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  • (PMID = 19753235.001).
  • [ISSN] 0019-5413
  • [Journal-full-title] Indian journal of orthopaedics
  • [ISO-abbreviation] Indian J Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2740360
  • [Keywords] NOTNLM ; Late onset of paraplegia in adolescents / anterior decompression / management
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79. Christensen MS, Heyman M, Möttönen M, Zeller B, Jonmundsson G, Hasle H, Nordic Society of Paediatric Haematology and Oncology (NOPHO): Treatment-related death in childhood acute lymphoblastic leukaemia in the Nordic countries: 1992-2001. Br J Haematol; 2005 Oct;131(1):50-8
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  • [Title] Treatment-related death in childhood acute lymphoblastic leukaemia in the Nordic countries: 1992-2001.
  • Despite continuously more successful treatment of childhood acute lymphoblastic leukaemia (ALL), 2-5% of children still die of other causes than relapse.
  • The Nordic Society of Paediatric Haematology and Oncology-ALL92 protocol included 1652 patients < or =15 years of age with precursor B- and T-cell ALL diagnosed between 1992 and 2001.
  • Infections still remain a major challenge in childhood ALL.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bacterial Infections / mortality. Cause of Death. Child. Down Syndrome / complications. Down Syndrome / mortality. Down Syndrome / therapy. Female. Hematopoietic Stem Cell Transplantation / adverse effects. Humans. Male. Opportunistic Infections / mortality. Remission Induction. Risk Factors. Scandinavian and Nordic Countries / epidemiology. Sex Factors. Treatment Outcome

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  • (PMID = 16173962.001).
  • [ISSN] 0007-1048
  • [Journal-full-title] British journal of haematology
  • [ISO-abbreviation] Br. J. Haematol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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80. Crawford JR, Zaninovic A, Santi M, Rushing EJ, Olsen CH, Keating RF, Vezina G, Kadom N, Packer RJ: Primary spinal cord tumors of childhood: effects of clinical presentation, radiographic features, and pathology on survival. J Neurooncol; 2009 Nov;95(2):259-269
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  • [Title] Primary spinal cord tumors of childhood: effects of clinical presentation, radiographic features, and pathology on survival.
  • To determine the relationship between clinical presentation, radiographic features, pathology, and treatment on overall survival of newly diagnosed pediatric primary spinal cord tumors (PSCT).
  • Twenty-five pediatric patients (15 boys, average 7.9 years) were diagnosed with PSCT.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Humans. Infant. Male. Neoplasm Staging. Prognosis. Retrospective Studies. Survival Rate

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  • (PMID = 19521666.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / K12 NS052159; United States / NINDS NIH HHS / NS / K12NS052159-01A1
  • [Publication-type] Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] AU0V1LM3JT / Gadolinium
  • [Other-IDs] NLM/ PMC2759024
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81. Campana D: Role of minimal residual disease monitoring in adult and pediatric acute lymphoblastic leukemia. Hematol Oncol Clin North Am; 2009 Oct;23(5):1083-98, vii
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  • [Title] Role of minimal residual disease monitoring in adult and pediatric acute lymphoblastic leukemia.
  • Assays that measure minimal residual disease (MRD) can determine the response to treatment in patients with acute lymphoblastic leukemia (ALL) much more precisely than morphologic screening of bone marrow smears.
  • The clinical significance of MRD, detected by flow cytometry or polymerase chain reaction-based methods in childhood ALL, has been established.

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  • (PMID = 19825454.001).
  • [ISSN] 1558-1977
  • [Journal-full-title] Hematology/oncology clinics of North America
  • [ISO-abbreviation] Hematol. Oncol. Clin. North Am.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA060419-13; United States / NCI NIH HHS / CA / CA21765; United States / NCI NIH HHS / CA / R01 CA060419; United States / NCI NIH HHS / CA / CA60419; United States / NCI NIH HHS / CA / P30 CA021765; None / None / / R01 CA060419-13; United States / NCI NIH HHS / CA / U01 CA060419
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 95
  • [Other-IDs] NLM/ NIHMS132490; NLM/ PMC2762949
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82. Leonardi D, Polizzotti N, Carta A, Gelsomino R, Sava L, Vigneri R, Calaciura F: Longitudinal study of thyroid function in children with mild hyperthyrotropinemia at neonatal screening for congenital hypothyroidism. J Clin Endocrinol Metab; 2008 Jul;93(7):2679-85
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  • Thyroid function and morphology were evaluated in 44 "false positive" children up to advanced childhood (8.0 +/- 0.7 yr of age).
  • In these children a high prevalence (50%) of subclinical hypothyroidism in early childhood (2.8 +/- 0.5 yr) had already been described.
  • RESULTS: At an average of 5.3 yr, subclinical hypothyroidism persisted in 19 of 44 (43.2%) children and, more specifically, in two of three of those who had increased TSH in early childhood.
  • Euthyroidism was present in all cases that were euthyroid in early childhood, although they had TSH and free T(3) values significantly higher than control children with a normal TSH at birth (TSH = 2.6 +/- 0.7 vs. 1.5 +/- 0.6 mU/liter, P < 0.001; free T(3) = 4.9 +/- 0.8 vs. 3.9 +/- 0.9 pmol/liter, P < 0.01).
  • The prevalence of hypothyroidism decreases with increasing age, but it is still high (>30%) in late childhood.
  • Even those "false positive" children that maintain euthyroidism in late childhood have an average TSH value that, although within the normal range, is higher than in normal controls, a possible marker of minor congenital thyroid function abnormalities.
  • [MeSH-minor] Child. Child, Preschool. False Positive Reactions. Humans. Infant, Newborn. Longitudinal Studies. Thyroxine / blood. Triiodothyronine / blood

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  • (PMID = 18445672.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 06LU7C9H1V / Triiodothyronine; 9002-71-5 / Thyrotropin; Q51BO43MG4 / Thyroxine
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83. Lewis MD, Lamm C, Segalowitz SJ, Stieben J, Zelazo PD: Neurophysiological correlates of emotion regulation in children and adolescents. J Cogn Neurosci; 2006 Mar;18(3):430-43
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  • Yet, there has been very little research on the neural underpinnings of emotion regulation across childhood and adolescence.
  • Negative emotion induction corresponded with an additional right ventral prefrontal or temporal generator beginning in middle childhood.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Electroencephalography. Evoked Potentials. Female. Humans. Male. Neurophysiology / methods. Reaction Time. Sex Characteristics. Size Perception

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  • (PMID = 16513007.001).
  • [ISSN] 0898-929X
  • [Journal-full-title] Journal of cognitive neuroscience
  • [ISO-abbreviation] J Cogn Neurosci
  • [Language] eng
  • [Grant] United States / NIMH NIH HHS / MH / 1R21 MH67357-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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84. Cruz AT, Ong LT, Starke JR: Childhood pleural tuberculosis: a review of 45 cases. Pediatr Infect Dis J; 2009 Nov;28(11):981-4
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  • [Title] Childhood pleural tuberculosis: a review of 45 cases.
  • No child developed relapse or recrudescence after therapy was discontinued.
  • [MeSH-minor] Adolescent. Antitubercular Agents / therapeutic use. Child. Child, Preschool. Female. Humans. Infant. Lung / pathology. Male. Radiography, Thoracic. Retrospective Studies. Texas / epidemiology. Treatment Outcome. Tuberculin Test

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  • (PMID = 19672211.001).
  • [ISSN] 1532-0987
  • [Journal-full-title] The Pediatric infectious disease journal
  • [ISO-abbreviation] Pediatr. Infect. Dis. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antitubercular Agents
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85. Yong MH, Hwang WS, Knight LA, Fung W, Chan MY, Seow WT, Chui CH: Comparing histopathological classification with MYCN, 1p36 and 17q status detected by fluorescence in situ hybridisation from 14 untreated primary neuroblastomas in Singapore. Singapore Med J; 2009 Nov;50(11):1090-4
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  • INTRODUCTION: Neuroblastoma is the most common extracranial solid tumour in children, accounting for about 5.3 percent of all childhood cancers in Singapore.
  • [MeSH-minor] Child, Preschool. Chromosome Deletion. Chromosomes, Human, Pair 1. Chromosomes, Human, Pair 17. Gene Deletion. Humans. Infant. Neoplasms / genetics. Neoplasms / pathology. Prognosis. Singapore. Treatment Outcome

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  • (PMID = 19960166.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Singapore
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86. Gruhn B, Taub JW, Ge Y, Beck JF, Zell R, Häfer R, Hermann FH, Debatin KM, Steinbach D: Prenatal origin of childhood acute lymphoblastic leukemia, association with birth weight and hyperdiploidy. Leukemia; 2008 Sep;22(9):1692-7
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  • [Title] Prenatal origin of childhood acute lymphoblastic leukemia, association with birth weight and hyperdiploidy.
  • Recent studies with very small numbers of patients showed that in some cases of childhood acute lymphoblastic leukemia (ALL), preleukemic cells are detectable on Guthrie cards that were used for newborn screening.
  • High birth weight is an established risk factor for childhood ALL.
  • In conclusion, the majority of childhood B-precursor ALL arise prior to birth.
  • In the search for causes of childhood leukemia we should concentrate on prenatal factors as well as postnatal factors.
  • Our results suggest that autologous cord bloods could be a poor choice as the source of stem cells for transplantation in leukemia, which may contain preleukemic cells.
  • Pending the development of suitable methods, childhood leukemia is a potentially screenable disease.
  • [MeSH-major] Aneuploidy. Birth Weight. Precursor Cell Lymphoblastic Leukemia-Lymphoma / etiology. Preleukemia / pathology
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Gene Rearrangement. Humans. Immunoglobulin Heavy Chains. Infant. Infant, Newborn. Male. Neonatal Screening. Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / etiology. Retrospective Studies


87. Zehetbauer S, Wojahn T, Hiller KA, Schmalz G, Ruhl S: Resemblance of salivary protein profiles between children with early childhood caries and caries-free controls. Eur J Oral Sci; 2009 Aug;117(4):369-73
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  • [Title] Resemblance of salivary protein profiles between children with early childhood caries and caries-free controls.
  • Although prolonged bottle feeding with a carbohydrate-rich content is commonly agreed to be the main etiologic factor for early childhood caries (ECC), in recent years additional endogenous factors, including the composition of saliva, have been suspected as predisposing factors in children for the development of this aggressive form of dental caries.
  • [MeSH-minor] Blotting, Western. Bottle Feeding / adverse effects. Cariostatic Agents / therapeutic use. Case-Control Studies. Child, Preschool. Concanavalin A. DMF Index. Densitometry. Dietary Carbohydrates / adverse effects. Electrophoresis, Polyacrylamide Gel. Female. Fluorides / therapeutic use. Food Habits. Fucose. Glycoproteins / analysis. Hemolysin Proteins. Humans. Image Processing, Computer-Assisted. Lectins. Male. Oral Hygiene. Peanut Agglutinin. Polysaccharides / analysis. Risk Factors. Silver Staining

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  • (PMID = 19627346.001).
  • [ISSN] 1600-0722
  • [Journal-full-title] European journal of oral sciences
  • [ISO-abbreviation] Eur. J. Oral Sci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Cariostatic Agents; 0 / Dietary Carbohydrates; 0 / Glycoproteins; 0 / Hemolysin Proteins; 0 / Lectins; 0 / Peanut Agglutinin; 0 / Polysaccharides; 0 / Salivary Proteins and Peptides; 0 / fucose-binding lectin; 11028-71-0 / Concanavalin A; 3713-31-3 / Fucose; Q80VPU408O / Fluorides
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88. Boomsma DI, van Beijsterveldt CE, Hudziak JJ: Genetic and environmental influences on Anxious/Depression during childhood: a study from the Netherlands Twin Register. Genes Brain Behav; 2005 Nov;4(8):466-81
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  • [Title] Genetic and environmental influences on Anxious/Depression during childhood: a study from the Netherlands Twin Register.
  • For a large sample of twin pairs from the Netherlands Twins Register who were recruited at birth and followed through childhood, we obtained parental ratings of Anxious/Depression (A/D).
  • Anxious/Depression, unlike many other common childhood psychopathologies, is influenced by the shared family environment.
  • [MeSH-major] Anxiety / genetics. Child Behavior / physiology. Depression / genetics. Models, Genetic. Personality / genetics
  • [MeSH-minor] Adult. Age Factors. Child. Child, Preschool. Environment. Family Health. Female. Humans. Longitudinal Studies. Male. Netherlands. Observer Variation. Personality Inventory. Registries. Sex Factors. Twins, Dizygotic / genetics. Twins, Monozygotic / genetics

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  • (PMID = 16268991.001).
  • [ISSN] 1601-1848
  • [Journal-full-title] Genes, brain, and behavior
  • [ISO-abbreviation] Genes Brain Behav.
  • [Language] eng
  • [Grant] United States / NIMH NIH HHS / MH / MH 58799
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Twin Study
  • [Publication-country] England
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89. Azevedo-Silva F, Reis Rde S, Santos Mde O, Luiz RR, Pombo-de-Oliveira MS: Evaluation of childhood acute leukemia incidence and underreporting in Brazil by capture-recapture methodology. Cancer Epidemiol; 2009 Dec;33(6):403-5
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  • [Title] Evaluation of childhood acute leukemia incidence and underreporting in Brazil by capture-recapture methodology.
  • Childhood acute lymphoblastic leukemia (ALL) is said to have lower incidence in developing countries, which has implications for its pathogenesis, but there are few studies concerning the completeness of cancer registries in developing countries.
  • This study analyzes the number of cases and incidence of childhood acute lymphoblastic leukemia in three different cities in Brazil and estimates underreporting cases and possible PBCR failures.
  • METHODS: We evaluated the completeness of PBCR and the incidence rates of childhood ALL from three different Brazilian cities using the two-source capture-recapture method.
  • The estimated completeness of childhood ALL in PBCRs was 15.5%, 35.4% and 29.2%, respectively, for Salvador, Recife and Belo Horizonte.
  • CONCLUSIONS: There was a high estimated underreporting of childhood leukemia cases in some Brazilian cities.
  • Childhood acute lymphoblastic leukemia incidence rates are similar to those of developed countries.
  • [MeSH-major] Disease Notification / statistics & numerical data. Population Surveillance. Precursor Cell Lymphoblastic Leukemia-Lymphoma / epidemiology
  • [MeSH-minor] Adolescent. Brazil / epidemiology. Child. Child, Preschool. Female. Humans. Incidence. Infant. Male. Registries

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  • [CommentIn] Cancer Epidemiol. 2009 Dec;33(6):401-2 [19932647.001]
  • (PMID = 19833572.001).
  • [ISSN] 1877-783X
  • [Journal-full-title] Cancer epidemiology
  • [ISO-abbreviation] Cancer Epidemiol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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90. Pan C, Tang JY, Xue HL, Chen J, Dong L, Zhou M, Ye QD, Wang YP: [Clinical report on diagnosis and treatment of 14 cases with pediatric Ewing's sarcoma family tumors]. Zhonghua Er Ke Za Zhi; 2009 Mar;47(3):179-82
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  • [Title] [Clinical report on diagnosis and treatment of 14 cases with pediatric Ewing's sarcoma family tumors].
  • OBJECTIVE: To recognize and improve the outcome of childhood Ewing's sarcoma family tumors, and to identify the efficacy and safety of the chemotherapy using RS-2002 Protocol.
  • CONCLUSIONS: Childhood Ewing's sarcoma family tumors were not very rare, and the prognosis was acceptable with optimal treatment.
  • [MeSH-minor] Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Infant. Male. Treatment Outcome

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  • (PMID = 19573430.001).
  • [ISSN] 0578-1310
  • [Journal-full-title] Zhonghua er ke za zhi = Chinese journal of pediatrics
  • [ISO-abbreviation] Zhonghua Er Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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91. Minhas V, Crabtree KL, Chao A, M'soka TJ, Kankasa C, Bulterys M, Mitchell CD, Wood C: Early childhood infection by human herpesvirus 8 in Zambia and the role of human immunodeficiency virus type 1 coinfection in a highly endemic area. Am J Epidemiol; 2008 Aug 1;168(3):311-20
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  • [Title] Early childhood infection by human herpesvirus 8 in Zambia and the role of human immunodeficiency virus type 1 coinfection in a highly endemic area.
  • Maternal and pediatric human immunodeficiency virus type 1 (HIV-1) infection status was also determined.
  • The results, based on 1,532 child-years of follow-up, showed that HHV-8 seroconversion occurs early in life.
  • The incidence rate of HHV-8 seroconversion was 13.8 infections per 100 child-years by 48 months of age.
  • Maternal HIV-1 and HHV-8 infection status were not independently associated with risk of HHV-8 seroconversion in the child.

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  • (PMID = 18515794.001).
  • [ISSN] 1476-6256
  • [Journal-full-title] American journal of epidemiology
  • [ISO-abbreviation] Am. J. Epidemiol.
  • [Language] ENG
  • [Grant] United States / FIC NIH HHS / TW / D43 TW01492; United States / NCI NIH HHS / CA / R01 CA075903; United States / NIAID NIH HHS / AI / T32 AI060547; United States / NCI NIH HHS / CA / R01 CA75903; United States / NCRR NIH HHS / RR / P20 RR016469; United States / NCRR NIH HHS / RR / P20 RR15635; United States / NCRR NIH HHS / RR / P20 RR015635
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2727264
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92. Seyhan M, Erdem T, Ertekin V, Selimoğlu MA: The mucocutaneous manifestations associated with celiac disease in childhood and adolescence. Pediatr Dermatol; 2007 Jan-Feb;24(1):28-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The mucocutaneous manifestations associated with celiac disease in childhood and adolescence.
  • This study was performed to detect the prevalence of mucocutaneous manifestations of celiac disease in childhood and adolescence and to investigate the relationship between these findings and duration of disease and a gluten-free diet.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Hair Diseases / epidemiology. Hair Diseases / etiology. Humans. Male. Mouth Mucosa. Nail Diseases / epidemiology. Nail Diseases / etiology. Prevalence


93. Jarfelt M, Lannering B, Bosaeus I, Johannsson G, Bjarnason R: Body composition in young adult survivors of childhood acute lymphoblastic leukaemia. Eur J Endocrinol; 2005 Jul;153(1):81-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Body composition in young adult survivors of childhood acute lymphoblastic leukaemia.
  • OBJECTIVE: Obesity is frequently reported in patients treated for childhood leukaemia.
  • DESIGN: All patients treated for acute lymphoblastic leukaemia (ALL) before the onset of puberty in the region of western Sweden, between 1973 and 1985, and in first remission, were included.
  • CONCLUSIONS: We found little effect on BMI but an increased percentage of total body fat, especially trunk fat, and a tendency for an unfavourable lipid profile in adult survivors of childhood leukaemia.

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  • (PMID = 15994749.001).
  • [ISSN] 0804-4643
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Leptin; 0 / Lipids
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94. Bosch K, Rosenbaum D: Gait symmetry improves in childhood--a 4-year follow-up of foot loading data. Gait Posture; 2010 Oct;32(4):464-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gait symmetry improves in childhood--a 4-year follow-up of foot loading data.
  • [MeSH-minor] Age Factors. Biomechanical Phenomena. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Male. Retrospective Studies

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  • [Copyright] Copyright © 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20678937.001).
  • [ISSN] 1879-2219
  • [Journal-full-title] Gait & posture
  • [ISO-abbreviation] Gait Posture
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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95. Conklin HM, Khan RB, Reddick WE, Helton S, Brown R, Howard SC, Bonner M, Christensen R, Wu S, Xiong X, Mulhern RK: Acute neurocognitive response to methylphenidate among survivors of childhood cancer: a randomized, double-blind, cross-over trial. J Pediatr Psychol; 2007 Oct;32(9):1127-39
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acute neurocognitive response to methylphenidate among survivors of childhood cancer: a randomized, double-blind, cross-over trial.
  • OBJECTIVE: To investigate the acute efficacy and adverse side effects of methylphenidate (MPH) among survivors of childhood cancer [acute lymphoblastic leukemia (ALL) or brain tumor (BT)] with learning impairments.
  • [MeSH-minor] Child. Child, Preschool. Cross-Over Studies. Double-Blind Method. Female. Humans. Male. Survival Rate. Wechsler Scales


96. Madsen KS, Baaré WF, Vestergaard M, Skimminge A, Ejersbo LR, Ramsøy TZ, Gerlach C, Akeson P, Paulson OB, Jernigan TL: Response inhibition is associated with white matter microstructure in children. Neuropsychologia; 2010 Mar;48(4):854-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cognitive control of thoughts, actions and emotions is important for normal behaviour and the development of such control continues throughout childhood and adolescence.
  • Though the brain's fibre tracts are known to develop during childhood, little is known about how fibre tract development within this network relates to developing behavioural control.
  • [MeSH-minor] Adolescent. Age Factors. Child. Female. Frontal Lobe / anatomy & histology. Functional Laterality / physiology. Humans. Image Processing, Computer-Assisted. Linear Models. Male. Motor Cortex / anatomy & histology. Neuropsychological Tests. Reaction Time / physiology

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  • [Copyright] Copyright (c) 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 19909763.001).
  • [ISSN] 1873-3514
  • [Journal-full-title] Neuropsychologia
  • [ISO-abbreviation] Neuropsychologia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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97. Sterker I, Frerich B: [Orbital diseases in childhood]. Klin Monbl Augenheilkd; 2006 Jan;223(1):59-67
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  • [Title] [Orbital diseases in childhood].
  • BACKGROUND: Orbital diseases in childhood are rare and differ from orbital lesions occurring in adults.
  • CONCLUSION: Awareness of orbital diseases in childhood, as a rare entity, is crucial for timely diagnosis and appropriate treatment, to save the vision and lives of affected children.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Cross-Sectional Studies. Diagnosis, Differential. Female. Humans. Incidence. Infant. Infant, Newborn. Male

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  • (PMID = 16418936.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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98. Raetz EA, Carroll WL: Eliminating a gold standard in childhood acute lymphoblastic leukemia? Pediatr Blood Cancer; 2006 Sep;47(3):242-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eliminating a gold standard in childhood acute lymphoblastic leukemia?
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy


99. Wang Z, Hu T, Cao LZ, Kang R, Zhao MY, Yu Y, Xu WQ: [Expression of WAVE1 in childhood acute lymphocytic leukemia and in the apoptosis of Jurkat cells induced by adriamycin]. Zhongguo Dang Dai Er Ke Za Zhi; 2008 Oct;10(5):620-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of WAVE1 in childhood acute lymphocytic leukemia and in the apoptosis of Jurkat cells induced by adriamycin].
  • OBJECTIVE: To investigate whether WASP/Verprolin homologous protein 1 (WAVE1) plays a role in the pathogenesis of childhood acute lymphoblastic leukemia (ALL).
  • [MeSH-major] Antibiotics, Antineoplastic / pharmacology. Apoptosis / drug effects. Doxorubicin / pharmacology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism. Wiskott-Aldrich Syndrome Protein Family / physiology
  • [MeSH-minor] Adolescent. Blotting, Western. Cell Proliferation / drug effects. Child. Child, Preschool. Female. Humans. Infant. Jurkat Cells. Male. RNA, Messenger / analysis

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  • (PMID = 18947485.001).
  • [ISSN] 1008-8830
  • [Journal-full-title] Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
  • [ISO-abbreviation] Zhongguo Dang Dai Er Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / RNA, Messenger; 0 / WASF1 protein, human; 0 / Wiskott-Aldrich Syndrome Protein Family; 80168379AG / Doxorubicin
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100. Henze G: Early postinduction intensification therapy is essential in childhood acute lymphoblastic leukemia. Nat Clin Pract Oncol; 2008 Sep;5(9):502-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Early postinduction intensification therapy is essential in childhood acute lymphoblastic leukemia.
  • Postinduction intensification therapy (PII) has been key to success in the treatment of many types of childhood cancer and has led to an increase in cure rates during the past 3 decades.
  • This Practice Point commentary discusses the recent findings of the Children's Cancer Group CCG-1961 study, which enrolled 2,078 children and adolescents with acute lymphoblastic leukemia.

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  • [CommentOn] Blood. 2008 Mar 1;111(5):2548-55 [18039957.001]
  • (PMID = 18648353.001).
  • [ISSN] 1743-4262
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Comment; Journal Article
  • [Publication-country] England
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