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1. Miranda J, Maciel A, Souza RM, Furtado AF, Malagueno E: [Proteic profile and antigenic recognition of extracts from Wuchereria bancrofti L3 infective larvae]. Rev Soc Bras Med Trop; 2005 Jan-Feb;38(1):27-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Proteic profile and antigenic recognition of extracts from Wuchereria bancrofti L3 infective larvae].
  • [Transliterated title] Perfil protéico e reconhecimento antigênico de extratos de larvas infectantes (L3) de Wuchereria bancrofti.
  • A study of protein characterization and recognition of the antigenic profile was accomplished in extracts of infective larvae (L3) from Wuchereria bancrofti.
  • Human sera and parasitized blood used to infect mosquitoes in order to obtain L3, were collected from microfilaraemic individuals living in a filariasis endemic area.
  • [MeSH-minor] Adolescent. Adult. Aged. Animals. Blotting, Western. Brazil. Child. Child, Preschool. Chronic Disease. Culex / parasitology. Electrophoresis, Polyacrylamide Gel. Female. Humans. Larva / chemistry. Larva / immunology. Male. Middle Aged. Wuchereria bancrofti / chemistry. Wuchereria bancrofti / immunology

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  • (PMID = 15717091.001).
  • [ISSN] 0037-8682
  • [Journal-full-title] Revista da Sociedade Brasileira de Medicina Tropical
  • [ISO-abbreviation] Rev. Soc. Bras. Med. Trop.
  • [Language] por
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Antigens, Helminth; 0 / Helminth Proteins
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2. Hidalgo-Ovejero AM, García-Mata S, Martínez-Lecea FJ, Goñi-Zubiri I, Alzueta-Zubiri L: L3-L4 dislocation without neurological lesions. Bull NYU Hosp Jt Dis; 2010;68(1):60-4
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  • [Title] L3-L4 dislocation without neurological lesions.
  • We present the case report of an L3-L4 dislocation, without neurological lesions, resulting from an airplane crash.
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Transplantation. Child. Child, Preschool. Female. Humans. Laminectomy. Magnetic Resonance Imaging. Middle Aged. Spinal Fusion / instrumentation. Tomography, X-Ray Computed. Traction. Treatment Outcome

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  • (PMID = 20345367.001).
  • [ISSN] 1936-9727
  • [Journal-full-title] Bulletin of the NYU hospital for joint diseases
  • [ISO-abbreviation] Bull NYU Hosp Jt Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Tachu B, Pillai S, Lucius R, Pogonka T: Essential role of chitinase in the development of the filarial nematode Acanthocheilonema viteae. Infect Immun; 2008 Jan;76(1):221-8
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  • Northern blot experiments and rapid amplification of cDNA ends-PCR with adult worms and larval stages showed that only one gene is expressed, with high variation in transcript levels, as determined by real-time PCR.
  • Chitinase transcript levels were lowest in the late male stage 4 larva (L4) and peaked in the stage 3 larva (L3), which was corroborated by Western blotting.
  • RNA interference (RNAi) experiments showed that treatment of L3 and adult female worms with double-stranded RNA of chitinase inhibited molting of L3 worms and hatching of microfilariae.

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  • (PMID = 17938220.001).
  • [ISSN] 1098-5522
  • [Journal-full-title] Infection and immunity
  • [ISO-abbreviation] Infect. Immun.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ EF052872/ EF052873/ U14638
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Helminth Proteins; EC 3.2.1.14 / Chitinase
  • [Other-IDs] NLM/ PMC2223640
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4. Naji M, Williams M, Hourihan MD, Collis RE: Shape of the thecal sac: L3/4 interspace compared with L4/5. Anaesthesia; 2009 Jan;64(1):39-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Shape of the thecal sac: L3/4 interspace compared with L4/5.
  • We retrospectively reviewed 60 normal magnetic resonance imaging scans to assess the anatomical shape of the thecal sac at the L3/4 and L4/5 vertebral interspaces.
  • In all cases the thecal sac was oval at L3/4 but in 26 (43%; 95% CI 31-55%) the thecal sac changed from oval at the L3/4 interspace to triangular at L4/5 (with the apex of the triangle presenting to the posterior epidural space).
  • [MeSH-minor] Adolescent. Adult. Dura Mater. Epidural Space / anatomy & histology. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Spinal Canal / anatomy & histology. Spinal Cord / anatomy & histology. Young Adult

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  • (PMID = 19087004.001).
  • [ISSN] 1365-2044
  • [Journal-full-title] Anaesthesia
  • [ISO-abbreviation] Anaesthesia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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5. Cheng HT, Chang YH, Chen YY, Lee TH, Tai DI, Lin DY: AFP-L3 in chronic liver diseases with persistent elevation of alpha-fetoprotein. J Chin Med Assoc; 2007 Aug;70(8):310-7
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  • [Title] AFP-L3 in chronic liver diseases with persistent elevation of alpha-fetoprotein.
  • The value of AFP-L3, which is more specific than AFP, was examined in such patients.
  • AFP-L3 measurement was done by lectin-affinity electrophoresis coupled with antibody-affinity blotting.
  • When the cutoff value of AFP-L3 ratio was 15%, both the sensitivity and specificity were 71% for prediction of HCC during the next 2 years in all patients.
  • Ninety percent of tumors larger than 5 cm had AFP-L3 > 15%, compared with only 60% for tumors smaller than 2 cm.
  • Three patients in group A had AFP-L3 ratio > 17.5%.
  • CONCLUSION: AFP-L3 provides a clue in HCC detection in patients with persistent elevation of AFP.
  • However, AFP-L3 could be highly elevated in severe hepatitis.
  • [MeSH-minor] Adult. Aged. Female. Hepatitis B, Chronic / blood. Hepatitis C, Chronic / blood. Humans. Male. Middle Aged. Sensitivity and Specificity. alpha-Fetoproteins

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  • (PMID = 17698430.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China (Republic : 1949- )
  • [Chemical-registry-number] 0 / AFP protein, human; 0 / Proteins; 0 / alpha-Fetoproteins
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6. Dixon H, Johnston CE, Else KJ: Antigen selection for future anti-Trichuris vaccines: a comparison of cytokine and antibody responses to larval and adult antigen in a primary infection. Parasite Immunol; 2008 Sep;30(9):454-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Antigen selection for future anti-Trichuris vaccines: a comparison of cytokine and antibody responses to larval and adult antigen in a primary infection.
  • Subcutaneous vaccination with adult excretory-secretory products (ES) protects susceptible mouse strains from T. muris.
  • Larval stages may contain novel and more relevant antigens which when incorporated in a vaccine induce worm expulsion earlier in infection than the adult worm products.
  • This study finds negligible difference in the cellular and humoral immune response to T. muris adult and third stage larva(e) (L3) ES during a primary T. muris infection, but identifies high molecular weight proteins in both adult and L3 ES as potential vaccine candidates.

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  • (PMID = 18565148.001).
  • [ISSN] 1365-3024
  • [Journal-full-title] Parasite immunology
  • [ISO-abbreviation] Parasite Immunol.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / / 068028
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Helminth; 0 / Antigens, Helminth; 0 / Cytokines; 0 / Immunoglobulin G; 0 / Vaccines
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7. Simcock DC, Brown S, Neale JD, Przemeck SM, Simpson HV: L3 and adult Ostertagia (Teladorsagia) circumcincta exhibit cyanide sensitive oxygen uptake. Exp Parasitol; 2006 Jan;112(1):1-7
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  • [Title] L3 and adult Ostertagia (Teladorsagia) circumcincta exhibit cyanide sensitive oxygen uptake.
  • Oxygen consumption by L3 and adult Ostertagia (Teladorsagia) circumcincta was examined in vitro to determine whether oxygen can be utilised in metabolism.
  • Rates of consumption (in nmol O2/h/1000 worms) were 13+/-1 in sheathed L3, 34+/-6 in ex-sheathed L3, and 1944+/-495 in adult worms.
  • Consumption was inhibited 95% by cyanide in L3 and 74% in adults.

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  • (PMID = 16198342.001).
  • [ISSN] 0014-4894
  • [Journal-full-title] Experimental parasitology
  • [ISO-abbreviation] Exp. Parasitol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] IY9XDZ35W2 / Glucose; MQD255M2ZO / Potassium Cyanide; S88TT14065 / Oxygen
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8. Don TA, Oksov Y, Lustigman S, Loukas A: Saposin-like proteins from the intestine of the blood-feeding hookworm, Ancylostoma caninum. Parasitology; 2007 Mar;134(Pt 3):427-36

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Both Ac-slp-1 and slp-2 mRNAs were shown to be expressed in all life stages assessed, with slp-1 predominantly being expressed in third-stage larvae (L3) before and after activation with dog serum.
  • These antisera were used as probes in fluorescence microscopy to localize the anatomic expression sites of both proteins to small, punctate organelles or vesicles within the intestinal cells of adult worms; weak staining was detected on the microvillar brush border of the intestine.
  • Using transmission electron microscopy, both proteins were localized to similar vesicles in the intestinal cells of the L3.
  • Their expression in the gut of the L3 and adult stages suggests a role for these hookworm SAPLIPs in the lysis of host cells during tissue migration and/or feeding.

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  • (PMID = 17109779.001).
  • [ISSN] 0031-1820
  • [Journal-full-title] Parasitology
  • [ISO-abbreviation] Parasitology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Helminth Proteins; 0 / RNA, Messenger; 0 / Recombinant Proteins; 0 / Saposins
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9. Delaney A, Williamson A, Brand A, Ashcom J, Varghese G, Goud GN, Hawdon JM: Cloning and characterisation of an aspartyl protease inhibitor (API-1) from Ancylostoma hookworms. Int J Parasitol; 2005 Mar;35(3):303-13
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  • Using sequence from the hookworm expressed sequence tag project, specific primers were designed and used to amplify Ac-api-1 from A. caninum infective L3 cDNA by PCR.
  • The A. ceylanicum api-1 cDNA of 878 bp was cloned from L3 cDNA using the A. caninum primers.
  • Ac-api-1 mRNA was detected by reverse transcriptase PCR in eggs, L1, L3 and adult life cycle stages.
  • A polyclonal antiserum against Escherichia coli expressed recombinant Ac-API-1 detected the protein in adult A. caninum excretory/secretory products, but not in those from activated infective larvae.
  • Immunolocalisation experiments using the antiserum indicated that Ac-API-1 is present primarily in the pseudocoelomic fluid in adult hookworms.
  • Soluble, yeast-expressed Ac-API-1 failed to inhibit pepsin or a hookworm gut aspartyl protease in vitro, but inhibited approximately 30% of the proteolytic activity of adult excretory/secretory products.
  • The pseudocoleomic location, presence in all life cycle stages, lack of inhibitory activity against pepsin, and inhibitory activity against excretory/secretory products suggest that Ac-API-1 inhibits an unidentified, putative aspartyl protease secreted by adult hookworms, and may be released as an enzyme-inhibitor complex.

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  • (PMID = 15722082.001).
  • [ISSN] 0020-7519
  • [Journal-full-title] International journal for parasitology
  • [ISO-abbreviation] Int. J. Parasitol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ AY705928/ AY705929
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Helminth; 0 / DNA, Complementary; 0 / DNA, Helminth; 0 / Protease Inhibitors; EC 3.4.23.- / Aspartic Acid Endopeptidases
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10. Murthy PK, Dixit S, Gaur RL, Kumar R, Sahoo MK, Shakya N, Joseph SK, Palne S, Gupta S: Influence of Brugia malayi life stages and BmAFII fraction on experimental Leishmania donovani infection in hamsters. Acta Trop; 2008 May;106(2):81-9
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  • The influence of live Brugia malayi parasites and a Sephadex G-200 fraction of the adult parasite extract (BmAFII) on the progression of Leishmania donovani infection was studied.
  • Inbred hamsters were first infected with B. malayi infective 3rd stage larvae (L3), adult worms or microfilariae (mf), and then with L. donovani amastigotes (Ld), or vice versa or received both the infections simultaneously; a group of animals were first immunized with BmAFII and then infected with Ld. L. donovani parasite burden was determined between 17 and 19 days post amastigote challenge (p.a.c.) and, in case of immunized animals, between 32 and 35 days p.a.c also.
  • Leishmanial parasite burden was significantly reduced in animals exposed to filarial L3 before amastigote inoculation and in animals given filarial adult worms after or together with amastigotes.
  • The findings show, for the first time, that B. malayi L3/adult worms or immunization with BmAFII inhibits progression of L. donovani infection in hamsters and this is associated with upregulation of NO and lymphocyte proliferative responses indicating that Th1 response might be responsible for this.

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  • (PMID = 18329620.001).
  • [ISSN] 0001-706X
  • [Journal-full-title] Acta tropica
  • [ISO-abbreviation] Acta Trop.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, Helminth; 31C4KY9ESH / Nitric Oxide
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11. Geiger SM, Fujiwara RT, Santiago H, Corrêa-Oliveira R, Bethony JM: Early stage-specific immune responses in primary experimental human hookworm infection. Microbes Infect; 2008 Nov-Dec;10(14-15):1524-35

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • After an initial rise in proliferative responses against larval and adult worm antigens, the cellular reactivity decreased until the end of pre-patency, rose again during patency, and dropped after chemotherapy.
  • Before infection and during the course of infection, elevated concentrations of TNF-alpha were detected in supernatants of peripheral blood mononuclear cells (PBMC) stimulated in vitro with third-stage (L3) or adult worm excretory-secretory (ES) antigens, which dropped off after chemotherapy.
  • After stimulation with L3 antigen, elevated concentrations of CCL17 were detected in supernatants during pre-patency and patency.

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  • (PMID = 18848637.001).
  • [ISSN] 1286-4579
  • [Journal-full-title] Microbes and infection
  • [ISO-abbreviation] Microbes Infect.
  • [Language] ENG
  • [Grant] United States / FIC NIH HHS / TW / K01TW00009
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antigens, Helminth; 0 / Chemokine CCL17; 0 / Tumor Necrosis Factor-alpha; 130068-27-8 / Interleukin-10
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12. Dixit S, Gaur RL, Sahoo MK, Joseph SK, Murthy PS, Murthy PK: Protection against L3 induced Brugia malayi infection in Mastomys coucha pre-immunized with BmAFII fraction of the filarial adult worm. Vaccine; 2006 Jul 26;24(31-32):5824-31

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  • [Title] Protection against L3 induced Brugia malayi infection in Mastomys coucha pre-immunized with BmAFII fraction of the filarial adult worm.
  • The present study was aimed at investigating protective efficacy of BmAFII (Sephadex G-200 eluted fraction of Brugia malayi adult worm extract) against establishment of infective larvae (L3)-induced B. malayi infection in Mastomys coucha and to delineate immunological responses induced in the host.
  • Healthy male M. coucha were immunized with BmAFII and subsequently inoculated with B. malayi L3.
  • Immunization with BmAFII reduced the adult worm recovery by 85.7% (P<0.001) and microfilaraemia by 77-95% of unimmunized controls (P<0.05-0.01).
  • Immunization alone resulted in downregulation of responses of cellular proliferation, IFN-gamma, TNF-alpha and NO production (P<0.01) but increased TGF-beta release (P<0.001) whereas the converse was seen after L3 inoculation in these animals.
  • In unimmunized+L3 inoculated animals all the above parameters were found downregulated (P<0.01-0.001).
  • The cell proliferative response of BmAFII immunized+L3 challenged animals was larger for Con A (P<0.001) but not for BmAFII.
  • Specific IgG levels were higher in immunized, immunized+L3 inoculated and unimmunized+L3 inoculated groups (P<0.001) compared to unimmunized animals, the highest level being shown by immunized+L3 inoculated group.
  • In conclusion, immunization with BmAFII suppresses establishment of L3-induced infection in M. coucha by stimulating proinflammatory responses to L3.

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  • (PMID = 16757067.001).
  • [ISSN] 0264-410X
  • [Journal-full-title] Vaccine
  • [ISO-abbreviation] Vaccine
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, Helminth
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13. Wang WM, Guan YG, Liu F, Wang TH, Xu XY, Ke Q, Lu YC, Yuan Y: [The influence of partial dorsal root rhizotomy on IGF-I expression in spared root ganglion and spinal cord]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2005 Jan;36(1):31-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To explore the temporospatial changes of IGF-I expression in the spared dorsal root ganglia (DRG, L6) on the operated side and un-operated side, in the spinal lamina II (L3, L5, L6) and Clarke's nucleus (L3) of the adult cats that have undergone partial dorsal rhizotomy, and compare them against those of the normal adult cats so as to unveil the relation between IGF-I and the plasticity of spinal cord.
  • METHODS: Fifteen male adult cats were divided into three groups.
  • The bilateral L6 dorsal root ganglia and L3, L5, L6 spinal cord of all groups were made into frozen sections 20 microm thick.
  • The distribution and the number of IGF-I positive neurons in bilateral spared DRG (L6) on the operated/un-operated side, in spinal lamina I (L3, L5, L6) and in Clarke' nucleus (L3) of each animal were observed and counted.
  • On the 14th day, the IGF-I expression in neurons of L6 DRG on the operated side was significantly lower than that of normal group and that of L6 spared DRG on the unoperated side (P<0.01), but it was not significantly different from that of the 7th day group (P>0.05). (2) There was no difference in number of IGF-I positive neuron in L3, L5, L6 spinal lamina II between normal group, 7th day post-operation group and 14th day post-operation group (P>0.05).

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  • (PMID = 15702774.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 67763-96-6 / Insulin-Like Growth Factor I
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14. Díaz-Camacho SP, Delgado-Vargas F, Willms K, de la Cruz-Otero Mdel C, Guadalupe Rendón-Maldonado J, Robert L, Antuna S, Nawa Y: Intrahepatic growth and maturation of Gnathostoma turgidum in the natural definitive opossum host, Didelphis virginiana. Parasitol Int; 2010 Sep;59(3):338-43

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The results show that tiny (<3mm in length) third stage larvae (L3) appeared in the liver of opossums around November and December.
  • Also in the liver, we found large L3 of up to about 10mm in length together with juveniles and mature adults from February to March.
  • In spite of their length, large L3 have 4 rows of hooklets, and their gonads remained undeveloped.
  • Morphological features of the small and large L3 of G. turgidum are described including scanning electron microscope images.
  • The seasonal switching of the several growth stages of G. turgidum from small L3 to adult worms in the liver and eventual migration to the stomach in opossums suggests the unique feature of G. turgidum utilizing the liver as the maturation site.

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  • (PMID = 20447468.001).
  • [ISSN] 1873-0329
  • [Journal-full-title] Parasitology international
  • [ISO-abbreviation] Parasitol. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA, Helminth; 0 / DNA, Ribosomal Spacer
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15. Huber A, Prosl H, Joachim A, Simpson HV, Pedley KC: Effects of excretory/secretory products of Haemonchus contortus on cell vacuolation. Parasitol Res; 2005 Jul;96(5):290-5
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  • We have used the latter approach to examine, at the cellular level, the effects of ES prepared from L3 and adult nematodes.
  • Both NR uptake and cellular vacuolation were increased following exposure to larval or adult ES products.
  • ES preparations from adult worms induced more extensive vacuolation then those from L3 worms and, as with VacA treatment, adherent cells remained viable despite high levels of vacuolation.

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  • (PMID = 15918071.001).
  • [ISSN] 0932-0113
  • [Journal-full-title] Parasitology research
  • [ISO-abbreviation] Parasitol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biological Factors; 0 / Helminth Proteins
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16. Kooyman FN, Ploeger HW, Höglund J, VAN Putten JP: Differential N-glycan- and protein-directed immune responses in Dictyocaulus viviparus-infected and vaccinated calves. Parasitology; 2007 Feb;134(Pt 2):269-79
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  • In the search for protection-inducing antigens, we found that several D. viviparus third-stage larval (L3) and adult ES products carry N-glycans.
  • Challenge infection resulted in increased specific serum antibody levels against ES and L3 in the re-infected and challenge control groups.

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  • (PMID = 17032477.001).
  • [ISSN] 0031-1820
  • [Journal-full-title] Parasitology
  • [ISO-abbreviation] Parasitology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Helminth; 0 / Immunodominant Epitopes; 0 / Polysaccharides
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17. Durazo FA, Blatt LM, Corey WG, Lin JH, Han S, Saab S, Busuttil RW, Tong MJ: Des-gamma-carboxyprothrombin, alpha-fetoprotein and AFP-L3 in patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma. J Gastroenterol Hepatol; 2008 Oct;23(10):1541-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Des-gamma-carboxyprothrombin, alpha-fetoprotein and AFP-L3 in patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma.
  • The study aim was to: (i) compare the levels of des-gamma-carboxyprothrombin (DCP), alpha-fetoprotein (AFP) and AFP-L3 in HCC patients and in chronic viral hepatitis patients without HCC;.
  • Receiver-operating curves (ROC) indicated that the cut-off value with the best sensitivity and specificity for each test was > or =84 mAU/mL for DCP, > or =25 ng/mL for AFP and > or =10% for AFP-L3.
  • The sensitivity, specificity and positive predictive value (PPV) for DCP was 87%, 85% and 86.8%, for AFP 69%, 87% and 69.8%, and for AFP-L3 56%, 90% and 56.1%, respectively.
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prothrombin. ROC Curve. Sensitivity and Specificity

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  • (PMID = 18422961.001).
  • [ISSN] 1440-1746
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / AFP protein, human; 0 / Biomarkers; 0 / Biomarkers, Tumor; 0 / Protein Precursors; 0 / alpha-Fetoproteins; 53230-14-1 / acarboxyprothrombin; 9001-26-7 / Prothrombin
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18. McVeigh P, Leech S, Marks NJ, Geary TG, Maule AG: Gene expression and pharmacology of nematode NLP-12 neuropeptides. Int J Parasitol; 2006 May 31;36(6):633-40
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  • Transcription was also identified in both L3 and adult stages of T. colubriformis, in which Tc-nlp-12 is expressed in a single tail neurone.
  • Conversely, As-nlp-12 is expressed in both head and tail tissue of adult female A. suum, suggesting species-specific differences in the transcription pattern of this gene.

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  • (PMID = 16600246.001).
  • [ISSN] 0020-7519
  • [Journal-full-title] International journal for parasitology
  • [ISO-abbreviation] Int. J. Parasitol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ AY347872/ DQ186899
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Caenorhabditis elegans Proteins; 0 / DNA, Complementary; 0 / DNA, Helminth; 0 / Helminth Proteins; 0 / Neuropeptides; 0 / aspartyl-tyrosyl-arginyl-prolyl-leucyl-glutaminyl-phenylalaninamide
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19. Lorente Moltó FJ, Martínez Garrido I: Retrospective review of L3 myelomeningocele in three age groups: should posterolateral iliopsoas transfer still be indicated to stabilize the hip? J Pediatr Orthop B; 2005 May;14(3):177-84
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  • [Title] Retrospective review of L3 myelomeningocele in three age groups: should posterolateral iliopsoas transfer still be indicated to stabilize the hip?
  • The data from 58 hips in 29 myelodysplastic children with L3 paralysis has been reviewed retrospectively.
  • All patients who were community walkers in adolescence maintained their function in adult life at the time of the review.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Hip Dislocation / etiology. Hip Dislocation / surgery. Humans. Immobilization. Joint Capsule / surgery. Male. Paralysis / etiology. Retrospective Studies. Treatment Outcome. Walking

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  • (PMID = 15812288.001).
  • [ISSN] 1060-152X
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Dávila C, Malagón D, Valero A, Benítez R, Adroher FJ: Anisakis simplex: CO(2)-fixing enzymes and development throughout the in vitro cultivation from third larval stage to adult. Exp Parasitol; 2006 Sep;114(1):10-5
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  • [Title] Anisakis simplex: CO(2)-fixing enzymes and development throughout the in vitro cultivation from third larval stage to adult.
  • The results showed that a high pCO(2), at a suitable temperature, is vital for the optimum development of these nematodes, at least from the third larval stage (L3) to adult.
  • Throughout the development of the worms studied, PEPCK activity was much higher than that of PEPC (e.g., 305 vs. 6.8 nmol/min.mg protein, respectively, in L3 collected from the host fish).
  • The activity of these enzymes in the worms cultivated in air + 5% CO(2) was highest during M3, and was also generally higher than that of those cultivated in air only, especially during molting from L3 to L4 (e.g., in recently molted L4, PEPCK activity was 3.7 times greater than that of PEPC 2.9 times greater than when cultivated in air).

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  • (PMID = 16600219.001).
  • [ISSN] 0014-4894
  • [Journal-full-title] Experimental parasitology
  • [ISO-abbreviation] Exp. Parasitol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide; EC 4.1.1.31 / Phosphoenolpyruvate Carboxylase; EC 4.1.1.49 / Phosphoenolpyruvate Carboxykinase (ATP)
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21. Wang Z, Abubucker S, Martin J, Wilson RK, Hawdon J, Mitreva M: Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation. BMC Genomics; 2010;11:307
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  • RESULTS: The generated transcripts from four developmental stages, infective L3, serum stimulated L3, adult male and adult female, covered 93% of the A. caninum transcriptome.
  • Examining the developmental expression profiles of A. caninum revealed major transitions in gene expression from larval stages to adult.
  • Adult males expressed the highest number of selectively expressed genes, but adult female expressed the highest number of selective parasitism-related genes.
  • Parasitism related genes were expressed more selectively in adult male and female worms.

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  • (PMID = 20470405.001).
  • [ISSN] 1471-2164
  • [Journal-full-title] BMC genomics
  • [ISO-abbreviation] BMC Genomics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Vaccines
  • [Other-IDs] NLM/ PMC2882930
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22. Giacomin PR, Wang H, Gordon DL, Botto M, Dent LA: Loss of complement activation and leukocyte adherence as Nippostrongylus brasiliensis develops within the murine host. Infect Immun; 2005 Nov;73(11):7442-9
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  • Substantive deposition of C3 and adherence of eosinophil-rich leukocytes were seen with infective-stage (L3) but not with lung-stage (L4) larvae.
  • Adult intestinal worms had low to intermediate levels of both C3 and leukocyte binding.
  • For L3 and adult worms, complement deposition was principally dependent on the alternative pathway.

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  • (PMID = 16239545.001).
  • [ISSN] 0019-9567
  • [Journal-full-title] Infection and immunity
  • [ISO-abbreviation] Infect. Immun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Complement C3; 0 / Complement C4; 80295-33-6 / Complement C1q; EC 3.4.21.47 / Complement Factor B
  • [Other-IDs] NLM/ PMC1273855
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23. Bricarello PA, Zaros LG, Coutinho LL, Rocha RA, Silva MB, Kooyman FN, De Vries E, Yatsuda AP, Amarante AF: Immunological responses and cytokine gene expression analysis to Cooperia punctata infections in resistant and susceptible Nelore cattle. Vet Parasitol; 2008 Aug 1;155(1-2):95-103
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  • Serum IgG1 mean levels against C. punctata antigens were higher in the resistant group, but significant differences between groups were only observed 14 days after the beginning of the experiment against infective larvae (L3) and 14 and 84 days against adult antigens.
  • The resistant group also presented higher IgA levels against C. punctata (L3 and adult) antigens with significant difference 14 days after the beginning of the trial (P<0.05).
  • In the small-intestine mucosa, levels of IgA anti-L3 and anti-adult C. punctata were higher in the resistant group, compared with the susceptible group (P<0.05).

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  • (PMID = 18513872.001).
  • [ISSN] 0304-4017
  • [Journal-full-title] Veterinary parasitology
  • [ISO-abbreviation] Vet. Parasitol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cytokines; 0 / Immunoglobulin A
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24. García-Coiradas L, Angulo-Cubillán F, Méndez S, Larraga V, de la Fuente C, Cuquerella M, Alunda JM: Isolation and immunolocalization of a putative protective antigen (p26/23) from adult Haemonchus contortus. Parasitol Res; 2009 Jan;104(2):363-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isolation and immunolocalization of a putative protective antigen (p26/23) from adult Haemonchus contortus.
  • The putative protective antigen, p26/23, from adult Haemonchus contortus was isolated.
  • A soluble extract from adult helminths obtained from the abomasa of hyperinfected (12,000 infective larvae) female Manchego lambs and treated with a mixture of protease inhibitors was subjected to affinity chromatography (hexylgluthatione) to eliminate the enzyme gluthatione S-transferase.
  • This allowed the isolation of a single protein, which was expressed in both infective larvae (L3) and the adult stage of the parasite.

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  • (PMID = 18825413.001).
  • [ISSN] 0932-0113
  • [Journal-full-title] Parasitology research
  • [ISO-abbreviation] Parasitol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Helminth; 0 / Antigens, Helminth
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25. Kiss JE, Gao X, Krepp JM, Hawdon JM: Interaction of hookworm 14-3-3 with the forkhead transcription factor DAF-16 requires intact Akt phosphorylation sites. Parasit Vectors; 2009 Apr 24;2(1):21
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Third-stage infective larvae (L3) of hookworms are in an obligatory state of developmental arrest that ends upon entering the definitive host, where they receive a signal that re-activates development.
  • Insulin-like signaling (ILS) mediates recovery from arrest in C. elegans and activation of hookworm dauer L3.
  • RESULTS: To determine if hookworm 14-3-3 proteins play a similar role in L3 activation, hookworm FTT-2 was identified and tested for its ability to interact with A. caninum DAF-16 in vitro.
  • Ac-FTT-2 was undetectable by Western blot in excretory/secretory products from serum-stimulated (activated) L3 or adult A. caninum.
  • CONCLUSION: The results indicate that Ac-FTT-2 interacts with DAF-16 in a phosphorylation-site dependent manner, and suggests that Ac-FTT-2 mediates activation of L3 by binding Ac-DAF-16 during hookworm infection.

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  • (PMID = 19393088.001).
  • [ISSN] 1756-3305
  • [Journal-full-title] Parasites & vectors
  • [ISO-abbreviation] Parasit Vectors
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI069293; United States / NIAID NIH HHS / AI / R01 AI069293-03; United States / NIAID NIH HHS / AI / R01 AI069293-01A1; United States / NIAID NIH HHS / AI / AI069293-02; United States / NIAID NIH HHS / AI / R21 AI062857; United States / NIAID NIH HHS / AI / AI069293-01A1; United States / NIAID NIH HHS / AI / AI069293-03; United States / NIAID NIH HHS / AI / R01 AI069293-02
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2683825
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26. Korhonen AM, Valanne JV, Jokela RM, Ravaska P, Volmanen P, Korttila K: Influence of the injection site (L2/3 or L3/4) and the posture of the vertebral column on selective spinal anesthesia for ambulatory knee arthroscopy. Acta Anaesthesiol Scand; 2005 Jan;49(1):72-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Influence of the injection site (L2/3 or L3/4) and the posture of the vertebral column on selective spinal anesthesia for ambulatory knee arthroscopy.
  • BACKGROUND: We tested the hypothesis that selective spinal anesthesia for ambulatory knee arthroscopy can be accomplished with a small dose of bupivacaine at the L3/4 interspace with or without a head-down tilt of 5 degrees when the patients were in the lateral decubitus position.
  • METHODS: In this double-blind study, 123 patients were randomly allocated to receive spinal anesthesia with 4 mg of hyperbaric bupivacaine inserted at either the L2/3 interspace, while the vertebral column was kept horizontal (L2/3 group), or the L3/4 level, with the vertebral column horizontal (L3/4H) or tilted 5 degrees head-down (L3/4T).
  • RESULTS: In the L3/4T group the sensory block (Th8) reached a significantly higher level 30 min after spinal injection, compared with both the L2/3 (Th10) and L3/4H (Th11) groups.
  • In the L3/4H group, 39% of the patients needed an additional tilt for 3 min at 7 min, compared with 10% (P=0.004) in the L3/4T group.
  • Sacral block developed later and recovered faster (P<0.05) in the L3/4T group compared to the L3/4H group.
  • A 4-mg dose of hyperbaric bupivacaine at the L3/4 interspace with a 5 degrees head-down tilt of the vertebral column for 6 min is recommended for knee arthroscopy.
  • [MeSH-minor] Adult. Body Mass Index. Double-Blind Method. Female. Head-Down Tilt. Humans. Male. Middle Aged. Monitoring, Intraoperative. Motor Neurons / drug effects. Nerve Block. Physical Stimulation. Prospective Studies

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  • (PMID = 15675986.001).
  • [ISSN] 0001-5172
  • [Journal-full-title] Acta anaesthesiologica Scandinavica
  • [ISO-abbreviation] Acta Anaesthesiol Scand
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Anesthetics, Local; Y8335394RO / Bupivacaine
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27. Mary KA, Hoti SL, Paily KP: Monoclonal antibodies generated against excretory/secretory antigens of mammalian stage larvae of the lymphatic filarial parasite Wuchereria bancrofti. J Immunoassay Immunochem; 2007;28(4):343-57

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Five Mabs were obtained and, among them, Mab A7 showed high reactivity against e/s antigens of L4 and crude somatic antigens of microfilariae (mf) of W. bancrofti, and infective stage (L3) and adult stage larvae of Brugia malayi.

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  • (PMID = 17885888.001).
  • [ISSN] 1532-1819
  • [Journal-full-title] Journal of immunoassay & immunochemistry
  • [ISO-abbreviation] J Immunoassay Immunochem
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Helminth; 0 / Antibodies, Monoclonal; 0 / Antigens, Helminth
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28. Iwata F, Shinjyo N, Amino H, Sakamoto K, Islam MK, Tsuji N, Kita K: Change of subunit composition of mitochondrial complex II (succinate-ubiquinone reductase/quinol-fumarate reductase) in Ascaris suum during the migration in the experimental host. Parasitol Int; 2008 Mar;57(1):54-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The flavoprotein (Fp) and small subunit of cytochrome b (CybS) in adult complex II differ from those of infective third stage larval (L3) complex II.
  • However, there is no difference in the iron-sulfur cluster (Ip) or the large subunit of cytochrome b (CybL) between adult and L3 isoforms of complex II.
  • In the present study, to clarify the changes that occur in the respiratory chain of A. suum larvae during their migration in the host, we examined enzymatic activity, quinone content and complex II subunit composition in mitochondria of lung stage L3 (LL3) A. suum larvae.
  • LL3 mitochondria showed higher QFR activity ( approximately 160 nmol/min/mg) than mitochondria of A. suum at other stages (L3: approximately 80 nmol/min/mg; adult: approximately 70 nmol/min/mg).
  • Interestingly, the results of two-dimensional bule-native/sodium dodecyl sulfate polyacrylamide gel electrophoresis analyses showed that LL3 mitochondria contained larval Fp (Fp(L)) and adult Fp (Fp(A)) at a ratio of 1:0.56, and that most LL3 CybS subunits were of the adult form (CybS(A)).

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  • (PMID = 17933581.001).
  • [ISSN] 1383-5769
  • [Journal-full-title] Parasitology international
  • [ISO-abbreviation] Parasitol. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies, Helminth; 0 / Protein Subunits; 0 / Quinones; EC 1.- / Oxidoreductases; EC 1.3.5.1 / Electron Transport Complex II; EC 1.3.99.- / quinol fumarate reductase
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29. Bonvehí P, Boutriau D, Casellas J, Weynants V, Feron C, Poolman J: Three doses of an experimental detoxified L3-derived lipooligosaccharide meningococcal vaccine offer good safety but low immunogenicity in healthy young adults. Clin Vaccine Immunol; 2010 Sep;17(9):1460-6
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Three doses of an experimental detoxified L3-derived lipooligosaccharide meningococcal vaccine offer good safety but low immunogenicity in healthy young adults.
  • This open, randomized phase I study evaluated the safety and reactogenicity of an experimental meningococcal serogroup B (MenB) vaccine obtained from outer membrane vesicle detoxified L3-derived lipooligosaccharide.
  • The immune responses ranged from 5% to 36% across experimental vaccines for the L3 H44-76 strain (versus 27% for the control), from 0% to 11% for the L3 NZ98/124 strain (versus 23% for the control), and from 0% to 13% for the L2 760676 strain (versus 59% for the control).
  • [MeSH-minor] Adolescent. Adult. Drug-Related Side Effects and Adverse Reactions. Fatigue / chemically induced. Female. Headache / chemically induced. Human Experimentation. Humans. Male. Neisseria meningitidis, Serogroup B / immunology. Pain / chemically induced. Secretory Vesicles / immunology. Serum Bactericidal Antibody Assay. Skin Diseases / chemically induced. Skin Diseases / pathology. Young Adult

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  • (PMID = 20660140.001).
  • [ISSN] 1556-679X
  • [Journal-full-title] Clinical and vaccine immunology : CVI
  • [ISO-abbreviation] Clin. Vaccine Immunol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lipopolysaccharides; 0 / Meningococcal Vaccines; 0 / lipid-linked oligosaccharides
  • [Other-IDs] NLM/ PMC2944444
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30. Brand AM, Varghese G, Majewski W, Hawdon JM: Identification of a DAF-7 ortholog from the hookworm Ancylostoma caninum. Int J Parasitol; 2005 Dec;35(14):1489-98
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Infective hookworm L3 encounter a host specific signal during invasion that re-activates suspended developmental pathways.
  • In the free-living nematode Caenorhabditis elegans, recovery from the developmentally arrested dauer stage in response to environmental cues is analogous to the resumption of development in invading hookworm L3.
  • An insulin-like signalling pathway mediates L3 activation in hookworms.
  • Sequence from a hookworm expressed sequence tag was used to design specific primers for PCR amplification of Ac-daf-7 from Ancylostoma caninum infective L3 cDNA.
  • Ac-daf-7 mRNA was strongly detected by reverse transcriptase PCR in L3 and serum stimulated L3 cDNA, and weakly in cDNA from L1 and adult life cycle stages.
  • Antiserum against Escherichia coli expressed recombinant Ac-DAF-7 detected the mature protein in L3 and adult soluble extracts, but not in excretory/secretory products from serum stimulated L3 or adults.
  • Increased expression in arrested L3 stages suggests that Ac-daf-7 is important for developmental arrest.

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  • (PMID = 16135366.001).
  • [ISSN] 0020-7519
  • [Journal-full-title] International journal for parasitology
  • [ISO-abbreviation] Int. J. Parasitol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ DQ058687/ DQ059758
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Helminth; 0 / Caenorhabditis elegans Proteins; 0 / DAF-7 protein, C elegans; 0 / Transforming Growth Factor beta
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31. Nisbet AJ, Bell NE, McNeilly TN, Knox DP, Maizels RM, Meikle LI, Wildblood LA, Matthews JB: A macrophage migration inhibitory factor-like tautomerase from Teladorsagia circumcincta (Nematoda: Strongylida). Parasite Immunol; 2010 Jul;32(7):503-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A cDNA representing Tci-mif-1 was isolated following its identification in third-stage larvae (L3)-enriched cDNA population.
  • Messenger RNA (mRNA) representing the Tci-MIF-1 transcript was detected in eggs, L3 and adult stages of T. circumcincta.
  • Using immunohistochemistry, the Tci-MIF-1 protein was shown to have a diffuse distribution in L3 tissue, and in L4 and adult stages, the protein was localized to the nematode gut.
  • A recombinant version of Tci-MIF-1 was produced, and enzymic assays indicated that this recombinant protein and a somatic extract of L3 possessed dopachrome tautomerase activity as has been observed previously in other MIF-like molecules.

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  • (PMID = 20591121.001).
  • [ISSN] 1365-3024
  • [Journal-full-title] Parasite immunology
  • [ISO-abbreviation] Parasite Immunol.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Complementary; 0 / DNA, Helminth; 0 / Helminth Proteins; EC 5.3.- / Intramolecular Oxidoreductases; EC 5.3.3.12 / dopachrome isomerase
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32. Freedman BA, Horton WC, Rhee JM, Edwards CC 2nd, Kuklo TR: Reliability analysis for manual radiographic measures of rotatory subluxation or lateral listhesis in adult scoliosis. Spine (Phila Pa 1976); 2009 Mar 15;34(6):603-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reliability analysis for manual radiographic measures of rotatory subluxation or lateral listhesis in adult scoliosis.
  • OBJECTIVE: To define the inter- and intraobserver reliability of 3 measures of rotatory subluxation (RS) in adult scoliosis (AS).
  • RS at L3/4 was most common (35%).
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Arthritis / radiography. Female. Humans. Male. Middle Aged. Observer Variation. Reproducibility of Results. Retrospective Studies. Young Adult

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  • (PMID = 19282739.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] United States
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33. Liu TT, Bannatyne BA, Maxwell DJ: Organization and neurochemical properties of intersegmental interneurons in the lumbar enlargement of the adult rat. Neuroscience; 2010 Dec 1;171(2):461-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Organization and neurochemical properties of intersegmental interneurons in the lumbar enlargement of the adult rat.
  • Intersegmental interneurons with relatively short axons perform an important role in the coordination of limb movement but surprisingly little is known about their organization and how they contribute to neuronal networks in the adult rat.
  • The b-subunit of cholera toxin was injected into L1 or L3 segments of seven rats in the vicinity of lateral or medial motor nuclei.
  • In contrast, 19% of all intra-segmental axons in the L3 contralateral lateral motor nucleus were found to be purely glycinergic and 17% contained a mixture of GABA and glycine.

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  • [Copyright] Copyright © 2010 IBRO. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20849930.001).
  • [ISSN] 1873-7544
  • [Journal-full-title] Neuroscience
  • [ISO-abbreviation] Neuroscience
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / R01 NS040863
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calb2 protein, rat; 0 / Calbindin 2; 0 / Calbindins; 0 / S100 Calcium Binding Protein G; EC 2.3.1.6 / Choline O-Acetyltransferase
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34. Schwab F, el-Fegoun AB, Gamez L, Goodman H, Farcy JP: A lumbar classification of scoliosis in the adult patient: preliminary approach. Spine (Phila Pa 1976); 2005 Jul 15;30(14):1670-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A lumbar classification of scoliosis in the adult patient: preliminary approach.
  • OBJECTIVE: To create a preliminary approach to a clinically important classification of scoliosis in adult patients.
  • METHODS: A total of 98 adult patients with scoliosis with a 2-year minimum treatment/follow-up were included.
  • Patients were classified into one of 3 types of deformity based on the degree of lordosis (L1-S1) and frontal plane endplate obliquity of L3 on standing radiographs: type I = lordosis > 55 degrees, L3 obliquity < 15 degrees; type II = lordosis 35 degrees-55 degrees, L3 obliquity 15 degrees-25 degrees; and type III = lordosis < 35 degrees, L3 obliquity > 25 degrees.
  • Significant correlation between endplate obliquity L3, L1-S1 lordosis and VAS was noted (P < 0.05).
  • CONCLUSIONS: A simple classification of adult scoliosis was developed based on frontal and sagittal plane standing radiographs.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disability Evaluation. Follow-Up Studies. Humans. Lordosis / classification. Lordosis / radiography. Lordosis / therapy. Low Back Pain / classification. Low Back Pain / radiography. Low Back Pain / therapy. Middle Aged. Retrospective Studies. Treatment Failure

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  • (PMID = 16025039.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Albitar M, Potts SJ, Giles FJ, O'Brien S, Keating M, Thomas D, Clarke C, Jilani I, Aguilar C, Estey E, Kantarjian H: Proteomic-based prediction of clinical behavior in adult acute lymphoblastic leukemia. Cancer; 2006 Apr 1;106(7):1587-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proteomic-based prediction of clinical behavior in adult acute lymphoblastic leukemia.
  • BACKGROUND: Response in adult acute lymphoblastic leukemia (ALL) can be achieved in a majority of patients.
  • However, unlike pediatric ALL, recurrence is common in adult ALL, and the ability to predict at an early stage which patients are most likely to experience recurrence may help in devising new therapeutic approaches to prevent recurrence.
  • Positive prediction of L3 morphological classification was achieved in 80% of test cases.
  • [MeSH-major] Decision Trees. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology. Proteomics
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Child, Preschool. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prognosis. Protein Array Analysis. Recurrence

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16518825.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Nunes AC, Duarte RB, Sousa TB, dos Santos JR, Freire MA, Costa MS: Expression of the immediate-early gene egr-1 and substance P in the spinal cord following locomotor training in adult rats. Brain Res; 2010 Jul 23;1345:125-36

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of the immediate-early gene egr-1 and substance P in the spinal cord following locomotor training in adult rats.
  • Here we evaluated the expression of both Egr-1 and SP in the sacrolumbar area of the spinal cord after locomotor training in adult rats.
  • Increased neuronal Egr-1 expression was found in the spinal cord sections in rats that underwent locomotor training, especially in laminae IV and X across L3-S4 levels (p<0.05).

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20546710.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Early Growth Response Protein 1; 0 / Egr1 protein, rat; 33507-63-0 / Substance P
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37. Gudaityte J, Marchertiene I, Pavalkis D, Saladzinskas Z, Tamelis A, Tokeris I: [Minimal effective dose of spinal hyperbaric bupivacaine for adult anorectal surgery: a double-blind, randomized study]. Medicina (Kaunas); 2005;41(8):675-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Minimal effective dose of spinal hyperbaric bupivacaine for adult anorectal surgery: a double-blind, randomized study].
  • The aim of the study was to find minimal effective dose of spinal hyperbaric bupivacaine for adult anorectal surgery.
  • METHODS: The study included 93 adult consecutive patients admitted for anorectal operations.
  • Dural puncture was made before surgery in the sitting position at L3-L4 or L4-L5 with 25-26G Tamanho spinal needle (BBraun, Germany) and different volumes of hyperbaric bupivacaine (Marcaine Spinal Heavy 0.5%, AstraZeneca) were injected over 2 minutes: group 1 (n=17) 1.5 ml, group 2 (n=38) 1.0 ml, group 3 (n=38) 0.8 ml.
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Data Interpretation, Statistical. Double-Blind Method. Female. Humans. Male. Middle Aged. Patient Satisfaction. Postoperative Complications. Time Factors

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  • (PMID = 16160416.001).
  • [ISSN] 1648-9144
  • [Journal-full-title] Medicina (Kaunas, Lithuania)
  • [ISO-abbreviation] Medicina (Kaunas)
  • [Language] lit
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] Lithuania
  • [Chemical-registry-number] 0 / Anesthetics, Local; Y8335394RO / Bupivacaine
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38. Jiang XJ, Wang JS, Fang Q: [Gene expression of breast cancer resistance protein in adult acute lymphocytic leukemia and its clinical significance]. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2008 Feb;16(1):31-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Gene expression of breast cancer resistance protein in adult acute lymphocytic leukemia and its clinical significance].
  • The objective of this study was to investigate the relationship between the expressions of breast cancer resistance protein (BCRP) gene and drug resistance as well as prognosis in adult patients with acute lymphocytic leukemia (ALL).
  • Semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) was used to detect the expression of BCRP gene in 97 adult patients with acute lymphocytic leukemia (ALL) and 30 normal subjects.
  • In ALL subtypes BCRP gene expression of L3 type was distinctly higher than that of L(1), L(2) types.
  • It is concluded that the high expression of BCRP gene may induce clinical drug resistance, and may be an unfavorable factor for prognosis in adult patients with acute lymphocytic leukemia.

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  • (PMID = 18315895.001).
  • [ISSN] 1009-2137
  • [Journal-full-title] Zhongguo shi yan xue ye xue za zhi
  • [ISO-abbreviation] Zhongguo Shi Yan Xue Ye Xue Za Zhi
  • [Language] CHI
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / ABCG2 protein, human; 0 / Neoplasm Proteins
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39. Tolhurst R, Theobald S, Kayira E, Ntonya C, Kafulafula G, Nielson J, van den Broek N: 'I don't want all my babies to go to the grave': perceptions of preterm birth in Southern Malawi. Midwifery; 2008 Mar;24(1):83-98
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Anecdotes as Topic. Female. Fetal Death / prevention & control. Focus Groups. Humans. Infant, Newborn. Malawi. Medicine, Traditional. Mothers / psychology. Nurse's Role. Nurse-Patient Relations. Patient Compliance / psychology. Pregnancy. Prenatal Care / methods. Risk Factors. Rural Population. Self Concept. Social Support. Socioeconomic Factors

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  • (PMID = 17240496.001).
  • [ISSN] 0266-6138
  • [Journal-full-title] Midwifery
  • [ISO-abbreviation] Midwifery
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
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40. Burmeister T, Schwartz S, Horst HA, Rieder H, Gökbuget N, Hoelzer D, Thiel E: Molecular heterogeneity of sporadic adult Burkitt-type leukemia/lymphoma as revealed by PCR and cytogenetics: correlation with morphology, immunology and clinical features. Leukemia; 2005 Aug;19(8):1391-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular heterogeneity of sporadic adult Burkitt-type leukemia/lymphoma as revealed by PCR and cytogenetics: correlation with morphology, immunology and clinical features.
  • Chromosomal translocations involving the MYC oncogene are a hallmark of Burkitt lymphoma but they are only found in a varying frequency in mature Burkitt-type acute lymphoblastic leukemia (B-ALL).
  • We have investigated samples of 56 sporadic Burkitt leukemia/lymphoma patients for the translocations t(8;14)(q24;q32), t(2;8)(p11;q24) and t(8;22)(q24;q11).
  • A typical L3 or L3-compatible cytomorphology was highly predictive (>80%) but not specific of a MYC translocation.
  • [MeSH-major] Burkitt Lymphoma / genetics. Genetic Heterogeneity. Translocation, Genetic
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Chromosomes, Human, Pair 14. Chromosomes, Human, Pair 8. Cytogenetic Analysis. Female. Genes, myc. Humans. Immunoglobulin Heavy Chains / genetics. Male. Middle Aged. Polymerase Chain Reaction. Survival Rate

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  • [Copyright] Leukemia (2005) 19, 1391-1398.
  • (PMID = 15973450.001).
  • [ISSN] 0887-6924
  • [Journal-full-title] Leukemia
  • [ISO-abbreviation] Leukemia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Immunoglobulin Heavy Chains
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41. Puneet P, Moochhala S, Bhatia M: Chemokines in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol; 2005 Jan;288(1):L3-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chemokines in acute respiratory distress syndrome.
  • Acute lung injury that clinically manifests as acute respiratory distress syndrome (ARDS) is caused by an uncontrolled systemic inflammatory response resulting from clinical events including major surgery, trauma, multiple transfusions, severe burns, pancreatitis, and sepsis.
  • [MeSH-major] Chemokines / metabolism. Respiratory Distress Syndrome, Adult / physiopathology

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  • (PMID = 15591040.001).
  • [ISSN] 1040-0605
  • [Journal-full-title] American journal of physiology. Lung cellular and molecular physiology
  • [ISO-abbreviation] Am. J. Physiol. Lung Cell Mol. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chemokines; 0 / Receptors, Chemokine
  • [Number-of-references] 122
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42. Bellis MA, Hughes K, Anderson Z, Tocque K, Hughes S: Contribution of violence to health inequalities in England: demographics and trends in emergency hospital admissions for assault. J Epidemiol Community Health; 2008 Dec;62(12):1064-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • With disproportionate exposure to violence in poorer areas even in those under 15, early life primary prevention initiatives are required in disadvantaged communities to reduce childhood harm and the development of adult perpetrators and victims of violence.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Cross-Sectional Studies. Demography. England / epidemiology. Female. Humans. Infant. Infant, Newborn. Male. Middle Aged. Young Adult

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  • (PMID = 18628267.001).
  • [ISSN] 1470-2738
  • [Journal-full-title] Journal of epidemiology and community health
  • [ISO-abbreviation] J Epidemiol Community Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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43. Vanezis A, Lees A: A biomechanical analysis of good and poor performers of the vertical jump. Ergonomics; 2005 Sep 15-Nov 15;48(11-14):1594-603

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Ankle Joint / physiology. Biomechanical Phenomena. Hip Joint / physiology. Humans. Isometric Contraction. Knee Joint / physiology. Male. Soccer / physiology

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  • (PMID = 16338725.001).
  • [ISSN] 0014-0139
  • [Journal-full-title] Ergonomics
  • [ISO-abbreviation] Ergonomics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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44. Green DJ, Swart A, Exterkate A, Naylor LH, Black MA, Cable NT, Thijssen DH: Impact of age, sex and exercise on brachial and popliteal artery remodelling in humans. Atherosclerosis; 2010 Jun;210(2):525-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Age Factors. Aged. Body Composition. Female. Humans. Life Style. Longitudinal Studies. Male. Middle Aged

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  • [Copyright] Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
  • [CommentIn] Atherosclerosis. 2010 Jun;210(2):366 [20362291.001]
  • (PMID = 20197189.001).
  • [ISSN] 1879-1484
  • [Journal-full-title] Atherosclerosis
  • [ISO-abbreviation] Atherosclerosis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
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45. Beynon C, McVeigh J, Hurst A, Marr A: Older and sicker: Changing mortality of drug users in treatment in the North West of England. Int J Drug Policy; 2010 Sep;21(5):429-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Age Factors. Cause of Death. Employment. England / epidemiology. Humans. Middle Aged

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20172707.001).
  • [ISSN] 1873-4758
  • [Journal-full-title] The International journal on drug policy
  • [ISO-abbreviation] Int. J. Drug Policy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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46. Dawson EA, Black MA, Pybis J, Cable NT, Green DJ: The impact of exercise on derived measures of central pressure and augmentation index obtained from the SphygmoCor device. J Appl Physiol (1985); 2009 Jun;106(6):1896-901
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Exercise Test. Humans. Male. Muscle Tonus / physiology. Muscle, Smooth, Vascular / physiology. Pulsatile Flow. Radial Artery / physiology. Systole. Vascular Resistance / physiology

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  • (PMID = 19342433.001).
  • [ISSN] 8750-7587
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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47. McGarry JW, Ortiz PL, Hodgkinson JE, Goreish I, Williams DJ: PCR-based differentiation of Fasciola species (Trematoda: Fasciolidae), using primers based on RAPD-derived sequences. Ann Trop Med Parasitol; 2007 Jul;101(5):415-21

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although the identification of adult Fasciola to species level is traditionally based on differences in size and shape, recent studies have demonstrated this method to be unreliable.

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  • (PMID = 17550647.001).
  • [ISSN] 0003-4983
  • [Journal-full-title] Annals of tropical medicine and parasitology
  • [ISO-abbreviation] Ann Trop Med Parasitol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Helminth
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48. Downing J, Cook PA, Madden HC, Phillips-Howard PA, Higgins SP, Bellis MA: Management of cases testing positive for gonococcal infection in a community-based chlamydia screening programme. Sex Transm Infect; 2010 Nov;86(6):474-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Ambulatory Care. Community Health Services. England. Female. Humans. Male. Mass Screening / standards. Sensitivity and Specificity. Young Adult

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  • (PMID = 20940161.001).
  • [ISSN] 1472-3263
  • [Journal-full-title] Sexually transmitted infections
  • [ISO-abbreviation] Sex Transm Infect
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 83905-01-5 / Azithromycin
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49. Bellis MA, Hughes K, Tocque K, Hennell T, Humphrey G, Wyke S: Assessing and communicating the health and judicial impact of alcohol use. Public Health; 2005 Apr;119(4):253-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Aged. Alcohol Drinking / adverse effects. Alcohol Drinking / mortality. Female. Great Britain / epidemiology. Humans. Male. Middle Aged. Poverty

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  • (PMID = 15733684.001).
  • [ISSN] 0033-3506
  • [Journal-full-title] Public health
  • [ISO-abbreviation] Public Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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50. Leerapun A, Suravarapu SV, Bida JP, Clark RJ, Sanders EL, Mettler TA, Stadheim LM, Aderca I, Moser CD, Nagorney DM, LaRusso NF, de Groen PC, Menon KV, Lazaridis KN, Gores GJ, Charlton MR, Roberts RO, Therneau TM, Katzmann JA, Roberts LR: The utility of Lens culinaris agglutinin-reactive alpha-fetoprotein in the diagnosis of hepatocellular carcinoma: evaluation in a United States referral population. Clin Gastroenterol Hepatol; 2007 Mar;5(3):394-402; quiz 267
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND & AIMS: The percentage of Lens culinaris agglutinin-reactive (alpha)-fetoprotein (AFP-L3%) is proposed as a diagnostic and prognostic marker for hepatocellular carcinoma (HCC).
  • We evaluated the utility of AFP-L3% for diagnosis of HCC in a US referral population.
  • The AFP-L3% was measured using a clinical auto-analyzer.
  • RESULTS: The AFP-L3% is not reported for a total alpha-fetoprotein (AFP) less than 10 ng/mL, and all patients with an AFP greater than 200 ng/mL had HCC; thus the AFP-L3% was noninformative for these patients.
  • In patients with a total AFP of 10-200 ng/mL, an AFP-L3% greater than 10% had a sensitivity of 71% and a specificity of 63% for diagnosis of HCC.
  • An AFP-L3% greater than 35% had a reduced sensitivity of 33%, but an increased specificity of 100%.
  • The high specificity of the AFP-L3% cut-off of 35% allowed the confident diagnosis of an additional 10% of HCCs not diagnosed using an AFP cut-off of 200 ng/mL.
  • After adjustment for AFP level, no association was observed between AFP-L3% and tumor size, stage, vascular invasion, grade, or survival.
  • We found that an AFP-L3% greater than 35% has 100% specificity for HCC in these patients.
  • AFP-L3%, used in combination with AFP, may be a clinically useful adjunct marker for the diagnosis of HCC.

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  • (PMID = 17368240.001).
  • [ISSN] 1542-7714
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA082862-01; United States / NCI NIH HHS / CA / K08 CA082862-02; United States / NCI NIH HHS / CA / CA100882; United States / NCI NIH HHS / CA / K08 CA082862-04; United States / NCI NIH HHS / CA / K08 CA082862-01; United States / NCI NIH HHS / CA / R01 CA100882; United States / NCI NIH HHS / CA / CA100882-03; United States / NCI NIH HHS / CA / R01 CA100882-01A1; United States / NCI NIH HHS / CA / K08 CA082862-05; United States / NCI NIH HHS / CA / CA100882-02; United States / NCI NIH HHS / CA / R01 CA100882-02; United States / NCI NIH HHS / CA / CA082862-05; United States / NCI NIH HHS / CA / CA082862-02; United States / NCI NIH HHS / CA / R01 CA100882-03; United States / NCI NIH HHS / CA / K08 CA082862-03; United States / NCI NIH HHS / CA / CA082862-04; United States / NCI NIH HHS / CA / CA82862; United States / NCI NIH HHS / CA / K08 CA082862; United States / NCI NIH HHS / CA / CA082862-03; United States / NCI NIH HHS / CA / R56 CA100882
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Plant Lectins; 0 / alpha-Fetoproteins; 0 / lentil lectin
  • [Other-IDs] NLM/ NIHMS20613; NLM/ PMC1931510
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51. Lattimore P, Hutchinson R: Perceived calorie intake and state body-image satisfaction in women attempting weight loss: a preliminary investigation. Body Image; 2010 Jan;7(1):15-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Affect. Body Mass Index. Body Size. Body Weight. Cues. Diet, Reducing / psychology. Female. Humans. Middle Aged. Self Concept. Surveys and Questionnaires

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  • [Copyright] Copyright 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 19783237.001).
  • [ISSN] 1873-6807
  • [Journal-full-title] Body image
  • [ISO-abbreviation] Body Image
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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52. Mackridge AJ, Marriott JF: Returned medicines: waste or a wasted opportunity? J Public Health (Oxf); 2007 Sep;29(3):258-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Drug Stability. England. Female. Humans. Incineration. Infant. Male. Middle Aged

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  • [CommentIn] J Public Health (Oxf). 2008 Jun;30(2):209; author reply 209-10 [18281323.001]
  • (PMID = 17579236.001).
  • [ISSN] 1741-3842
  • [Journal-full-title] Journal of public health (Oxford, England)
  • [ISO-abbreviation] J Public Health (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Medical Waste Disposal; 0 / Pharmaceutical Preparations
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53. Bellis MA, Watson FL, Hughes S, Cook PA, Downing J, Clark P, Thomson R: Comparative views of the public, sex workers, businesses and residents on establishing managed zones for prostitution: analysis of a consultation in Liverpool. Health Place; 2007 Sep;13(3):603-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Consumer Participation. England. Female. Geography. HIV Infections / prevention & control. Humans. Residence Characteristics. Substance-Related Disorders / prevention & control. Surveys and Questionnaires

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  • (PMID = 17029923.001).
  • [ISSN] 1353-8292
  • [Journal-full-title] Health & place
  • [ISO-abbreviation] Health Place
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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54. Graham DL, Carail M, Caris-Veyrat C, Lowe GM: Cigarette smoke and human plasma lycopene depletion. Food Chem Toxicol; 2010 Aug-Sep;48(8-9):2413-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Antioxidants / metabolism. Biomarkers / metabolism. Chromatography, High Pressure Liquid. Electrophoresis, Polyacrylamide Gel. Female. Humans. Isomerism. Lipoproteins, LDL / blood. Male. Middle Aged. Molsidomine / analogs & derivatives. Molsidomine / pharmacology. Oxidation-Reduction. Solutions. Young Adult

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  • [Copyright] Copyright (c) 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20621663.001).
  • [ISSN] 1873-6351
  • [Journal-full-title] Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • [ISO-abbreviation] Food Chem. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Biomarkers; 0 / Lipoproteins, LDL; 0 / Solutions; 36-88-4 / Carotenoids; 5O5U71P6VQ / linsidomine; D46583G77X / Molsidomine; SB0N2N0WV6 / lycopene
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55. Bellis MA, Hughes K, Calafat A, Juan M, Ramon A, Rodriguez JA, Mendes F, Schnitzer S, Phillips-Howard P: Sexual uses of alcohol and drugs and the associated health risks: a cross sectional study of young people in nine European cities. BMC Public Health; 2008;8:155
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adolescent Behavior. Adult. Age Factors. Cross-Sectional Studies. Europe / epidemiology. Female. Humans. Logistic Models. Male. Street Drugs. Surveys and Questionnaires

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  • (PMID = 18471281.001).
  • [ISSN] 1471-2458
  • [Journal-full-title] BMC public health
  • [ISO-abbreviation] BMC Public Health
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Street Drugs
  • [Other-IDs] NLM/ PMC2409330
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56. Kawai K, Kojima T, Miyanaga N, Hattori K, Hinotsu S, Shimazui T, Akaza H: Lectin-reactive alpha-fetoprotein as a marker for testicular tumor activity. Int J Urol; 2005 Mar;12(3):284-9
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Lens culinaris agglutin (LCA)-affinity electrophoresis resolves serum alpha-fetoprotein (AFP) into three isoforms, AFP-L1, -L2 and -L3.
  • The ratio of AFP-L3 to total AFP (AFP-L3%) is frequently high in hepatocellular carcinoma (HCC) patients, and thus, it is widely used for early diagnosis of HCC.
  • In testicular tumor patients, the broad band of AFP-L2 could not be completely separated from AFP-L3.
  • The mean ratio of AFP-L3 plus AFP-L2 (AFP-L2 + 3%) was as high as 94% (range 80-99%) in these patients.
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Feasibility Studies. Humans. Lectins / metabolism. Male. Neoplasm Staging. Orchiectomy. Protein Isoforms

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  • (PMID = 15828957.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Lectins; 0 / Protein Isoforms; 0 / alpha-Fetoproteins
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57. Petersen CM, Rundquist PJ: Validation of spinal motion with the spine reposition sense device. J Neuroeng Rehabil; 2009;6:12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Sixty-five subjects performed seven trials of repositioning to a two-thirds full flexion position in sitting with X and Y displacement measurements taken at the T4 and L3 levels.
  • The thoracolumbar angle between the T4 and the L3 level was computed and compared between the positions tested.
  • A two (vertebral level of thoracic and lumbar) by seven (trials) mixed model repeated measures ANOVA indicated whether significant differences were present between the thoracic (T4) and lumbar (L3) angular measurements.
  • RESULTS: Calculated thoracolumbar angles between T4 and L3 were significantly different for all positions tested indicating spinal movement was occurring with testing.
  • [MeSH-minor] Biomechanical Phenomena. Female. Hip. Humans. Lumbar Vertebrae. Male. Posture. Thoracic Vertebrae. Young Adult

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  • (PMID = 19386126.001).
  • [ISSN] 1743-0003
  • [Journal-full-title] Journal of neuroengineering and rehabilitation
  • [ISO-abbreviation] J Neuroeng Rehabil
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2695817
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58. Hodgkinson JE, Freeman KL, Lichtenfels JR, Palfreman S, Love S, Matthews JB: Identification of strongyle eggs from anthelmintic-treated horses using a PCR-ELISA based on intergenic DNA sequences. Parasitol Res; 2005 Mar;95(4):287-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Horses were treated with pyrantel embonate (PYR) to remove adult strongyles followed, 7 days later, by a 5-day course of FBZ.

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  • (PMID = 15682337.001).
  • [ISSN] 0932-0113
  • [Journal-full-title] Parasitology research
  • [ISO-abbreviation] Parasitol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antinematodal Agents; 0 / DNA, Helminth; 0 / DNA, Intergenic; 621BVT9M36 / Fenbendazole; 81BK194Z5M / Pyrantel Pamoate
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59. Boakye DA, Baidoo HA, Glah E, Brown C, Appawu M, Wilson MD: Monitoring lymphatic filariasis interventions: Adult mosquito sampling, and improved PCR - based pool screening method for Wuchereria bancrofti infection in Anopheles mosquitoes. Filaria J; 2007;6:13

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Monitoring lymphatic filariasis interventions: Adult mosquito sampling, and improved PCR - based pool screening method for Wuchereria bancrofti infection in Anopheles mosquitoes.
  • PCR-based methods are preferred over classical dissections but the best protocol so far achieved detection of one L3 Wuchereria bancrofti larva in a pool of 35-50 Anopheles mosquitoes.
  • Two DNA extraction methods; Bender buffer and phenol/chloroform purification, and DNAeasy Tissue kit (Quaigen Inc) were used on pools of 25, 50, 75 100 and 150 mosquitoes each seeded with one L3 or its quivalent amount of DNA.
  • Although PCR detection of one L3 in pools of 25, 50 and 75 mosquitoes was consistent irrespective of the extraction method, that of one L3 in 100 was only achieved with the kit-extracted DNA/Dynal bead purification method.

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  • [Cites] Trans R Soc Trop Med Hyg. 1994 Nov-Dec;88(6):665-6 [7886765.001]
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  • [Cites] Filaria J. 2006;5:2 [16504131.001]
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  • [Cites] J Infect Dis. 1995 Nov;172(5):1414-7 [7594692.001]
  • (PMID = 18047647.001).
  • [ISSN] 1475-2883
  • [Journal-full-title] Filaria journal
  • [ISO-abbreviation] Filaria J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2235849
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60. Kinoshita Y, Tajiri T, Souzaki R, Tatsuta K, Higashi M, Izaki T, Takahashi Y, Taguchi T: Diagnostic value of lectin reactive alpha-fetoprotein for neoinfantile hepatic tumors and malignant germ cell tumors: preliminary study. J Pediatr Hematol Oncol; 2008 Jun;30(6):447-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The AFP has 3 isoforms (L1, L2, L3), and the usefulness of the L3 fraction as a diagnostic marker for the adult hepatocellular carcinoma is well known.
  • In our analytical system (LiBASys), the level of the L3 fraction contains the majority of the L2 fraction.
  • The total AFP (ng/mL) level and the L3 fraction (%) were measured to assess the usefulness of the L3 fraction as a diagnostic marker.
  • RESULTS: In all cases of hepatoblastoma and yolk sac tumor, both the total AFP and the L3 fraction were high, either before treatment or in the presence of malignant tumors.
  • Most of the cases of neonatal immature teratoma showed a high total AFP level during the neoinfantile period, however, the L3 fraction was around 10%, and decreased after surgical treatment.
  • As the total AFP and the AFP-L3 fraction were proportionally elevated, the patient was treated with additional surgical resection and chemotherapy.
  • In the case of neonatal mature teratoma, the L3 fraction was below 0.5%, even when the total AFP level was high.
  • DISCUSSION: Our results indicated that the level of the L3 fraction accurately confirmed the existence, or the malignant potential of hepatic tumor or germ cell tumor.
  • The L3 fraction is useful as a tumor marker during the neoinfantile period.

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  • (PMID = 18525461.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Lectins; 0 / Protein Isoforms; 0 / alpha-Fetoproteins
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61. Duquette A, Roddier K, McNabb-Baltar J, Gosselin I, St-Denis A, Dicaire MJ, Loisel L, Labuda D, Marchand L, Mathieu J, Bouchard JP, Brais B: Mutations in senataxin responsible for Quebec cluster of ataxia with neuropathy. Ann Neurol; 2005 Mar;57(3):408-14
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Aged. Apraxias / complications. Apraxias / genetics. Arginine / genetics. Chromosomes, Human, Pair 9. DNA Mutational Analysis / methods. Family Health. Female. Glutamic Acid / genetics. Humans. Leucine / genetics. Linkage Disequilibrium. Lysine / genetics. Male. Middle Aged. Quebec. alpha-Fetoproteins / metabolism

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  • Hazardous Substances Data Bank. GLUTAMIC ACID HYDROCHLORIDE .
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  • (PMID = 15732101.001).
  • [ISSN] 0364-5134
  • [Journal-full-title] Annals of neurology
  • [ISO-abbreviation] Ann. Neurol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / alpha-Fetoproteins; 3KX376GY7L / Glutamic Acid; 94ZLA3W45F / Arginine; EC 3.6.1.- / SETX protein, human; EC 3.6.4.13 / RNA Helicases; GMW67QNF9C / Leucine; K3Z4F929H6 / Lysine
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62. Montgomery C, Fisk JE, Newcombe R: The nature of ecstasy-group related deficits in associative learning. Psychopharmacology (Berl); 2005 Jun;180(1):141-9
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  • [MeSH-minor] Adult. Dose-Response Relationship, Drug. Female. Humans. Male. Memory, Short-Term / drug effects

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  • (PMID = 15668817.001).
  • [ISSN] 0033-3158
  • [Journal-full-title] Psychopharmacology
  • [ISO-abbreviation] Psychopharmacology (Berl.)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Hallucinogens; KE1SEN21RM / N-Methyl-3,4-methylenedioxyamphetamine
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63. Arsenos G, Fortomaris P, Papadopoulos E, Sotiraki S, Stamataris C, Zygoyiannis D: Growth and meat quality of kids of indigenous Greek goats (Capra prisca) as influenced by dietary protein and gastrointestinal nematode challenge. Meat Sci; 2009 Jul;82(3):317-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The kids grazed in a pasture contaminated with L3 larvae of GIN.
  • Parasitic challenge was assessed by means of faecal egg counts (FEC), pasture larvae and adult nematodes in the GI tract of kids at slaughter.
  • The parasitic challenge of L3 on pasture reached its highest point at 42days and there were significant (P<0.01) differences between the numbers of Teladorsagia spp., Trichostrongylus spp., Haemonchus contortus, Oesophagostomum spp. and Chabertia spp. found in the GI tract of kids between the three groups; group A had the highest numbers.
  • Overall, the results showed that the increased protein content in the diet of growing kids grazing on a pasture contaminated with L3 nematode larvae resulted in the production of acceptable carcasses.

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  • (PMID = 20416724.001).
  • [ISSN] 0309-1740
  • [Journal-full-title] Meat science
  • [ISO-abbreviation] Meat Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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64. Johansson SE, Hejdeman B, Hinkula J, Johansson MH, Romagné F, Wahren B, Wagtmann NR, Kärre K, Berg L: NK cell activation by KIR-binding antibody 1-7F9 and response to HIV-infected autologous cells in viremic and controller HIV-infected patients. Clin Immunol; 2010 Feb;134(2):158-68
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  • Activation of NK cells was regulated by KIRs, because NK cell degranulation was increased by 1-7F9, a human antibody that binds KIR2DL1/L2/L3 and KIR2DS1/S2, and this effect was most pronounced in KIR haplotype B individuals.
  • [MeSH-minor] Adult. Female. Genotype. HLA-C Antigens / genetics. HLA-C Antigens / immunology. Humans. Jurkat Cells. Male. Middle Aged. Viremia

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  • [Copyright] Copyright 2009 Elsevier Inc. All rights reserved.
  • (PMID = 19880352.001).
  • [ISSN] 1521-7035
  • [Journal-full-title] Clinical immunology (Orlando, Fla.)
  • [ISO-abbreviation] Clin. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / HLA-C Antigens; 0 / Receptors, KIR
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65. Fullerton DG, Bruce N, Gordon SB: Indoor air pollution from biomass fuel smoke is a major health concern in the developing world. Trans R Soc Trop Med Hyg; 2008 Sep;102(9):843-51
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  • [Title] Indoor air pollution from biomass fuel smoke is a major health concern in the developing world.
  • One-third of the world's population burn organic material such as wood, dung or charcoal (biomass fuel) for cooking, heating and lighting.
  • This form of energy usage is associated with high levels of indoor air pollution and an increase in the incidence of respiratory infections, including pneumonia, tuberculosis and chronic obstructive pulmonary disease, low birthweight, cataracts, cardiovascular events and all-cause mortality both in adults and children.
  • The mechanisms behind these associations are not fully understood.
  • This review summarises the available information on biomass fuel use and health, highlighting the current gaps in knowledge.

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  • (PMID = 18639310.001).
  • [ISSN] 0035-9203
  • [Journal-full-title] Transactions of the Royal Society of Tropical Medicine and Hygiene
  • [ISO-abbreviation] Trans. R. Soc. Trop. Med. Hyg.
  • [Language] ENG
  • [Grant] United Kingdom / Wellcome Trust / / 080065
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Smoke
  • [Number-of-references] 82
  • [Other-IDs] NLM/ PMC2568866
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66. Abbott Z, Smuck M, Haig A, Sagher O: Irreversible spinal nerve injury from dorsal ramus radiofrequency neurotomy: a case report. Arch Phys Med Rehabil; 2007 Oct;88(10):1350-2
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  • She then received bilateral L3 and L4 medial branch and bilateral L5 dorsal ramus blocks with excellent temporary pain relief.
  • Subsequently she underwent bilateral L3 and L4 medial branch and bilateral L5 dorsal ramus RFN.
  • [MeSH-minor] Adult. Female. Humans. Radio Waves

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  • (PMID = 17908581.001).
  • [ISSN] 0003-9993
  • [Journal-full-title] Archives of physical medicine and rehabilitation
  • [ISO-abbreviation] Arch Phys Med Rehabil
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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67. Schulte TL, Adolphs B, Oberdiek D, Osada N, Liljenqvist U, Filler TJ, Marziniak M, Bullmann V: Approach-related lesions of the sympathetic chain in anterior correction and instrumentation of idiopathic scoliosis. Eur Spine J; 2010 Sep;19(9):1558-68
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Due to the suspected relevance of the sympathetic L2 ganglion, two groups were created: a T12 group, in which instrumentation down to T12 was carried out (n = 12), and an L3 group, in which instrumentation down to L3 was done (n = 12).
  • In the T12 group, mean temperatures of 29.6 degrees C on the side of the approach versus 29.5 degrees C on the control side were measured (P > 0.05); in the L3 group, the mean temperatures were 33.2 degrees C on the approach side versus 30.5 degrees C on the control side (P = 0.001).
  • A significant difference between the T12 group and the L3 group (P < 0.001) was observed on the approach side, but not on the control side (P = 0.15).
  • The ninhydrin sweat test showed reduced perspiration in 11 of 12 patients in the L3 group on the approach side in comparison with the control side (P = 0.002).
  • In the L3 group, they were found on the approach side only in 4 of 11 analyzable patients versus 11 patients on the control side.
  • In conclusion, anterior scoliosis instrumentation with a dual-rod system including vertebrae down to L3 regularly leads to lesions in the sympathetic trunk.
  • The caudal level of instrumentation (T12 vs. L3) has an impact on the extent of impairment, supporting the suspected importance of the L2 ganglion.
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Skin Temperature / physiology. Sweating / physiology. Young Adult

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  • (PMID = 20502925.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2989285
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68. Arvanitis LD: Melanotic schwannoma: a case with strong CD34 expression, with histogenetic implications. Pathol Res Pract; 2010 Oct 15;206(10):716-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We describe a case of a 36-year-old male who presented with a mass that was attached to the vertebral body as well as the nerve roots of L2 and L3.
  • [MeSH-minor] Adult. Humans. Immunohistochemistry. Male. Microscopy, Electron. S100 Proteins / analysis

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  • [Copyright] Copyright © 2010 Elsevier GmbH. All rights reserved.
  • (PMID = 20356686.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Melanins; 0 / S100 Proteins
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69. González RC, López AM, Rodriguez-Uría J, Alvarez D, Alvarez JC: Real-time gait event detection for normal subjects from lower trunk accelerations. Gait Posture; 2010 Mar;31(3):322-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We process the vertical and antero-posterior accelerations registered at the lower trunk (L3 vertebra).
  • [MeSH-minor] Acceleration. Adult. Female. Humans. Male. Signal Processing, Computer-Assisted

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  • [Copyright] Copyright 2009 Elsevier B.V. All rights reserved.
  • (PMID = 20034797.001).
  • [ISSN] 1879-2219
  • [Journal-full-title] Gait & posture
  • [ISO-abbreviation] Gait Posture
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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70. McMorland G, Suter E, Casha S, du Plessis SJ, Hurlbert RJ: Manipulation or microdiskectomy for sciatica? A prospective randomized clinical study. J Manipulative Physiol Ther; 2010 Oct;33(8):576-84
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

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  • METHODS: One hundred twenty patients presenting through elective referral by primary care physicians to neurosurgical spine surgeons were consecutively screened for symptoms of unilateral lumbar radiculopathy secondary to LDH at L3-4, L4-5, or L5-S1.
  • [MeSH-minor] Adult. Cross-Over Studies. Female. Humans. Lumbar Vertebrae. Male. Middle Aged. Outcome and Process Assessment (Health Care). Pain Measurement. Pilot Projects. Research Design. Severity of Illness Index. Treatment Outcome

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  • [Copyright] Copyright © 2010 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.
  • (PMID = 21036279.001).
  • [ISSN] 1532-6586
  • [Journal-full-title] Journal of manipulative and physiological therapeutics
  • [ISO-abbreviation] J Manipulative Physiol Ther
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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71. Schnyder M, Fahrion A, Riond B, Ossent P, Webster P, Kranjc A, Glaus T, Deplazes P: Clinical, laboratory and pathological findings in dogs experimentally infected with Angiostrongylus vasorum. Parasitol Res; 2010 Nov;107(6):1471-80
Zurich Open Access Repository and Archive. Full text from .

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  • Six beagles were orally inoculated with 50 (n=3) or 500 (n=3) A. vasorum third stage larvae (L3) obtained from experimentally infected Biomphalaria glabrata snails.
  • Dogs inoculated with 500 L3 exhibited earlier (from 42 dpi) and more severe respiratory signs.
  • Upon necropsy, 10 and 170 adult worms were recovered from the untreated dogs inoculated with 50 and 500 L3, respectively.
  • Adult worms were also found in two treated dogs, in the absence of L1 or eggs.
  • Infections starting from 50 L3 of A. vasorum had a massive impact on lung tissues and therefore on the health of affected dogs, particularly after prepatency, although only mild haematological abnormalities were evident.

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  • (PMID = 20700604.001).
  • [ISSN] 1432-1955
  • [Journal-full-title] Parasitology research
  • [ISO-abbreviation] Parasitol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anthelmintics; 0 / Imidazoles; 0 / Macrolides; 0 / Nitro Compounds; 3BN7M937V8 / imidacloprid; 51570-36-6 / milbemycin
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72. Marie-Magdeleine C, Mahieu M, D'Alexis S, Philibert L, Archimede H: In vitro effects of Tabernaemontana citrifolia extracts on Haemonchus contortus. Res Vet Sci; 2010 Aug;89(1):88-92
Hazardous Substances Data Bank. ALBENDAZOLE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Three extracts (aqueous, methanolic and dichloromethane) of T. citrifolia fruit, leaf and root were tested on four developmental stages of the parasite, using egg hatch assay (EHA), larval development assay (LDA), L3 migration inhibition assay (LMI), and adult worm motility assay (AWM).

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  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20117808.001).
  • [ISSN] 1532-2661
  • [Journal-full-title] Research in veterinary science
  • [ISO-abbreviation] Res. Vet. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anthelmintics; 0 / Plant Extracts; 2880D3468G / Levamisole; F4216019LN / Albendazole
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73. Abba K, Sudarsanam TD, Grobler L, Volmink J: Nutritional supplements for people being treated for active tuberculosis. Cochrane Database Syst Rev; 2008;(4):CD006086
MedlinePlus Health Information. consumer health - Tuberculosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Child. Humans. Randomized Controlled Trials as Topic. Tuberculosis, Pulmonary / diet therapy. Tuberculosis, Pulmonary / drug therapy

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  • [CommentIn] Evid Based Nurs. 2009 Jul;12(3):75 [19553412.001]
  • [UpdateIn] Cochrane Database Syst Rev. 2011;(11):CD006086 [22071828.001]
  • (PMID = 18843702.001).
  • [ISSN] 1469-493X
  • [Journal-full-title] The Cochrane database of systematic reviews
  • [ISO-abbreviation] Cochrane Database Syst Rev
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Review
  • [Publication-country] England
  • [Number-of-references] 42
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74. Armstrong WJ, McGregor SJ, Yaggie JA, Bailey JJ, Johnson SM, Goin AM, Kelly SR: Reliability of mechanomyography and triaxial accelerometry in the assessment of balance. J Electromyogr Kinesiol; 2010 Aug;20(4):726-31
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A single HRA was fixed superficial to L3/L4 segment to capture motions relative to the center-of-mass, and three-uniaxial accelerometers were fixed on the surface of the dominant leg correspondent to the vastus medialis (VM), vastus lateralis (VL), and soleus (SOL) muscles to record MMG.
  • [MeSH-minor] Adult. Electromyography. Female. Humans. Male. Myography. Reproducibility of Results. Signal Processing, Computer-Assisted

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  • [Copyright] Copyright (c) 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20227294.001).
  • [ISSN] 1873-5711
  • [Journal-full-title] Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology
  • [ISO-abbreviation] J Electromyogr Kinesiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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75. McJunkin TL, Wuollet AL, Lynch PJ: Sacral nerve stimulation as a treatment modality for intractable neuropathic testicular pain. Pain Physician; 2009 Nov-Dec;12(6):991-5
MedlinePlus Health Information. consumer health - Testicular Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Initially ilioinguinal, iliohypogastric, and genetofemoral nerve blocks; right-sided S1, S2, and S3 transforaminal epidural steroid injections (TFESIs) with inferior hypogastric blocks; and right-sided T12-L1, L1-L2, and L2-L3 TFESIs all failed to provide pain relief.
  • [MeSH-minor] Adult. Humans. Injections, Epidural / methods. Male. Pain / complications. Pain / radiography. Pain Measurement. Sacrococcygeal Region. Steroids / therapeutic use

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  • (PMID = 19935985.001).
  • [ISSN] 2150-1149
  • [Journal-full-title] Pain physician
  • [ISO-abbreviation] Pain Physician
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Steroids
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76. Okuda S, Oda T, Miyauchi A, Tamura S, Hashimoto Y, Yamasaki S, Haku T, Kanematsu F, Ariga K, Ohwada T, Aono H, Hosono N, Fuji T, Iwasaki M: Lamina horizontalization and facet tropism as the risk factors for adjacent segment degeneration after PLIF. Spine (Phila Pa 1976); 2008 Dec 1;33(25):2754-8
MedlinePlus Health Information. consumer health - Spine Injuries and Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lamina inclination angle at L3 and facet tropism at L3/4 in each group were measured 3 times by 3 individuals blinded to clinical results.
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Female. Humans. Male. Middle Aged. Retrospective Studies. Risk Factors. Spondylolisthesis / physiopathology. Spondylolisthesis / surgery

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  • (PMID = 19050581.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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77. Mawatari T, Miura H, Hamai S, Shuto T, Nakashima Y, Okazaki K, Kinukawa N, Sakai S, Hoffmann PF, Iwamoto Y, Keaveny TM: Vertebral strength changes in rheumatoid arthritis patients treated with alendronate, as assessed by finite element analysis of clinical computed tomography scans: a prospective randomized clinical trial. Arthritis Rheum; 2008 Nov;58(11):3340-9
Hazardous Substances Data Bank. Alendronic acid .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Thirty female RA patients without radiologic signs of L3 compression fractures or a history of osteoporosis medication were enrolled in a prospective randomized clinical trial.
  • [MeSH-minor] Adult. Aged. Female. Humans. Middle Aged. Prospective Studies

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  • (PMID = 18975334.001).
  • [ISSN] 0004-3591
  • [Journal-full-title] Arthritis and rheumatism
  • [ISO-abbreviation] Arthritis Rheum.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Density Conservation Agents; X1J18R4W8P / Alendronate
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78. Lu SB, Wang QY, Hai Y, Su QJ, Kang N, Zhang CS: [Total lumbar disc replacement with SB Charité III prosthesis: Chinese experience with more than two years follow-up]. Zhonghua Wai Ke Za Zhi; 2008 Mar 1;46(5):342-5
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  • One level replacement was done in 44 patients (L3,4 in 3, L4,5 in 23 and L5-S1 in 18), and two level procedures in 4 patients (L3,4/L4,5 in 1 and L4,5/L5-S1 in 3).
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Humans. Joint Prosthesis. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 18785528.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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79. Cho SK, Lenke LG, Hanson D: Traumatic noncontiguous double fracture-dislocation of the lumbosacral spine. Spine J; 2006 Sep-Oct;6(5):534-8
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  • The patient was transported to a major medical center where he was found to be conscious, and amazingly, his only major injury was fracture-dislocations of L2-L3 and L5-S1.
  • [MeSH-minor] Accidents, Traffic. Adult. Bone Screws. Bone Transplantation. Humans. Male. Paraparesis / etiology. Paraparesis / surgery. Treatment Outcome

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  • (PMID = 16934723.001).
  • [ISSN] 1529-9430
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Yu BS, Zhuang XM, Zheng ZM, Li ZM, Wang TP, Lu WW: Biomechanical advantages of dual over single iliac screws in lumbo-iliac fixation construct. Eur Spine J; 2010 Jul;19(7):1121-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Thus, the objective of this study was to compare the biomechanical effects of bilateral single and dual iliac screws on the stability of L3-iliac fixation construct under total sacrectomy condition.
  • After biomechanically testing the intact state simulated by L3-L5 pedicle screw fixation, destabilization was introduced by total sacrectomy.
  • Upon destabilization, L3-iliac screw-rod reconstructions were performed by four different techniques as follows:.
  • In compression, the stiffness of the L3-iliac fixation constructs of Single-Short, Single-Long, Dual-UL, and Dual-Lower techniques were 73, 76, 98, and 108% of the intact state, respectively.
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Biomechanical Phenomena. Bone Screws. Female. Humans. Internal Fixators. Male. Middle Aged

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  • [Cites] Osteoporos Int. 2000;11(5):408-10 [10912842.001]
  • [Cites] Spine (Phila Pa 1976). 2009 Jul 15;34(16):E565-72 [19770599.001]
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  • (PMID = 20195650.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2900011
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81. Fuentes S, Métellus P, Acosta-Diaz U, Pech-Gourg G, Dufour H, Grisoli F: [Minimally invasive transmuscular approach for the treatment of lumbar far lateral disc herniation]. Neurochirurgie; 2009 Feb;55(1):70-4
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  • The most commonly operated level was L3-L4 (46%), then L4-L5 (30.5%) and finally L2-L3 (15.5%).
  • [MeSH-minor] Adult. Aged. Endoscopy. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 18565547.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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82. Ringash J, Lockwood G, O'Sullivan B, Warde P, Bayley A, Cummings B, Kim J, Sellmann S, Waldron J: Hyperfractionated, accelerated radiotherapy for locally advanced head and neck cancer: quality of life in a prospective phase I/II trial. Radiother Oncol; 2008 May;87(2):181-7
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  • (L2) 62Gy, 1.55Gy/fraction; and (L3) 64Gy, 1.6Gy/fraction.
  • A mixed-model analysis of determinants of QOL showed no dose effect among L1 (n=22), L2 (n=26) or L3 (n=123).
  • [MeSH-minor] Adult. Aged. Dose Fractionation. Enteral Nutrition. Female. Humans. Male. Middle Aged. Prospective Studies. Radiotherapy Dosage. Survival Rate. Treatment Outcome

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  • (PMID = 18215435.001).
  • [ISSN] 0167-8140
  • [Journal-full-title] Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • [ISO-abbreviation] Radiother Oncol
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article
  • [Publication-country] Ireland
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83. Postigo I, Martinez J, Guisantes JA: Uncinaria stenocephala: assessment of antigens for the immunodiagnosis of canine uncinariosis. Exp Parasitol; 2006 Nov;114(3):215-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Three groups of sera from dogs (Group 1: dogs naturally infected only by U. stenocephala; Group 2: helminth-free dogs at necropsy, and Group 3: dogs parasitized by other helminths) were analyzed by ELISA using U. stenocephala antigens from adult worms (somatic and excretory-secretory antigens) and from L3 larvae (somatic antigens).
  • However, an analysis to assess the diagnostic value of the different antigens demonstrated that the adult excretory-secretory antigens had a higher diagnostic efficacy (96.7%), indicating that this is the best antigen source for the diagnosis of Uncinaria infection.

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  • (PMID = 16682029.001).
  • [ISSN] 0014-4894
  • [Journal-full-title] Experimental parasitology
  • [ISO-abbreviation] Exp. Parasitol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Helminth; 0 / Antigens, Helminth; 0 / Immune Sera
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84. Yang SH, Wang J, Xu WH, Li J, Liu GH, Yang C, Ye SN, Ye ZW, Liu Y: Shoulder hemiarthroplasty for the treatment of complex proximal humeral fractures. Chin J Traumatol; 2009 Feb;12(1):14-7
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  • The mean range of motion was 100 degrees (90 degrees-110 degrees) in abduction, 95 degrees (80 degrees-100 degrees) in forward flexion, 35 degrees (30 degrees-40 degrees) in external rotation and internal rotation was confined at L2 level (L1-L3).
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged

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  • (PMID = 19159510.001).
  • [ISSN] 1008-1275
  • [Journal-full-title] Chinese journal of traumatology = Zhonghua chuang shang za zhi
  • [ISO-abbreviation] Chin. J. Traumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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85. Bloch C, Kaiser A, Kuenzli E, Zappatore D, Haller S, Franceschini R, Luedi G, Radue EW, Nitsch C: The age of second language acquisition determines the variability in activation elicited by narration in three languages in Broca's and Wernicke's area. Neuropsychologia; 2009 Feb;47(3):625-33
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  • We tested the hypothesis that the age of L2 acquisition has an effect on the cortical representation of a multilingual repertoire in 44 multilinguals with different age of exposure to a L2 (simultaneous or covert simultaneous exposure to L1 and L2, sequential acquisition of L1 and L2 between 1 and 5 years, late learning of L2 after 9 years of age) and all fluent in a late learned L3.
  • Regional activation in a language production task showed a high in-between-subject variability, which was higher than within-subject variability between L1, L2, and L3.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Analysis of Variance. Female. Humans. Magnetic Resonance Imaging. Male. Young Adult

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  • (PMID = 19061905.001).
  • [ISSN] 0028-3932
  • [Journal-full-title] Neuropsychologia
  • [ISO-abbreviation] Neuropsychologia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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86. Miller MA, Bare SP, Recker RR, Smith SY, Fox J: Intratrabecular tunneling increases trabecular number throughout the skeleton of ovariectomized rhesus monkeys treated with parathyroid hormone 1-84. Bone; 2008 Jun;42(6):1175-83

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Daily treatment of ovariectomized (OVX) adult rhesus monkeys with human parathyroid hormone (PTH) 1-84 for 16 months increases trabecular bone volume (BV/TV), number (Tb.N) and connectivity at lumbar vertebra-3 (L3) and thoracic vertebra-10.
  • Using histomorphometry to determine frequency of events, we have now quantified intratrabecular tunneling at L3 and extended it to investigate the effects of PTH(1-84) treatment on trabecular bone at the proximal femur, distal radius and iliac crest of these animals.
  • At L3, tunneling frequency was low in control sham and OVX animals ( approximately 0.05/mm(2)) but increased significantly in PTH(1-84)-treated animals (0.27, 0.49 and 0.95/mm(2) with the 5, 10 and 25 microg/kg doses, respectively).

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  • (PMID = 18387869.001).
  • [ISSN] 8756-3282
  • [Journal-full-title] Bone
  • [ISO-abbreviation] Bone
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone
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87. Schoder M, Czerny M, Cejna M, Rand T, Stadler A, Sodeck GH, Gottardi R, Loewe C, Lammer J: Endovascular repair of acute type B aortic dissection: long-term follow-up of true and false lumen diameter changes. Ann Thorac Surg; 2007 Mar;83(3):1059-66
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  • [Title] Endovascular repair of acute type B aortic dissection: long-term follow-up of true and false lumen diameter changes.
  • BACKGROUND: The aim of this study was to determine the technical success after endovascular treatment of acute type B aortic dissections and to evaluate true and false lumen diameter changes at long-term follow-up.
  • METHODS: Twenty-eight patients with acute type B-dissection who were treated by stent graft repair presented with rupture (n = 1), contained rupture (n = 2), compromised branch vessels (n = 14), pleural effusion (n = 11), rapid aortic diameter progression (n = 5), persistent pain (n = 3), refractory hypertension (n = 10), and an aortic diameter of more than 4 cm (n = 4).
  • Taking into account the perfusion status of the false lumen, diameter changes were monitored in the thoracic aorta at the level of the stented segment (L1), distal to the stent graft (L2), and at the level of the celiac trunk (L3).
  • In L3, the false lumen thrombosed in only 22%, and the mean difference of false lumen diameter increase reached significance at the 2-year follow-up.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Aneurysm, Ruptured / therapy. Aorta, Abdominal / radiography. Aorta, Thoracic / radiography. Aortography. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Thrombosis / etiology. Thrombosis / radiography. Tomography, X-Ray Computed

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  • (PMID = 17307460.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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88. Herida M, de Barbeyrac B, Sednaoui P, Scieux C, Lemarchand N, Kreplak G, Clerc M, Timsit J, Goulet V, Desenclos JC, Semaille C: Rectal lymphogranuloma venereum surveillance in France 2004-2005. Euro Surveill; 2006 Sep;11(9):155-6
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  • Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis strains belonging to the L1, L2 or L3 genotype.
  • No L1 or L3 C. trachomatis genotype was found.
  • [MeSH-minor] Adult. Chlamydia trachomatis / genetics. Chlamydia trachomatis / isolation & purification. France / epidemiology. Genotype. Homosexuality, Male. Humans. Male. Retrospective Studies. Unsafe Sex

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  • [CommentIn] Euro Surveill. 2006 Sep;11(9):146-8 [17075163.001]
  • (PMID = 17075158.001).
  • [ISSN] 1560-7917
  • [Journal-full-title] Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin
  • [ISO-abbreviation] Euro Surveill.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] France
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89. Zhang D, Song Y: [The finite element analysis of lumbar fusions]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2006 Apr;20(4):400-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The maximal Von Mises stress of the adjacent L3.4 intervertebral finite all the models was ranked descendingly as flexion, lateral bending, torsion and extension.
  • [MeSH-minor] Adult. Biomechanical Phenomena. Humans. Male

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  • (PMID = 16683441.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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90. Berthold LD, Moritz JD, Soenksen S, Alzen G: [Assessment of bone density in children and adolescents by quantitative CT of one lumbar vertebra only]. Rofo; 2006 Mar;178(3):292-7
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  • The trabecular bone density was measured (1-cm slice, 80 kV, 81 mAs) in L1 through L3.
  • RESULTS: The mean bone density in the lumbar vertebrae was 139.9 mg/ml calcium-hydroxylapatite per ml bone in L1, 133.9 in L2, and 131.7 in L3, and the mean of all three vertebrae was 135.2 mg/ml.
  • On average, L3 was 3.5 mg/ml below the mean (SD 4.6 mg/ml).
  • [MeSH-minor] Absorptiometry, Photon. Adolescent. Adult. Age Factors. Child. Child, Preschool. Female. Humans. Infant. Male. Sex Factors

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  • (PMID = 16508836.001).
  • [ISSN] 1438-9029
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Germany
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91. Mörl F, Blickhan R: Three-dimensional relation of skin markers to lumbar vertebrae of healthy subjects in different postures measured by open MRI. Eur Spine J; 2006 Jun;15(6):742-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Skin markers and lumbar vertebrae L3 and L4 were examined by vertically open magnetic resonance imaging (MRI) within different postures to investigate whether, and to which extent the position and orientation of skin markers represent the corresponding information of assigned underlying vertebra.
  • Skin markers were fixed at lumbar levels L3 and L4.
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male. Movement

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  • (PMID = 16047207.001).
  • [ISSN] 0940-6719
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC3489463
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92. Usha N, Shashidhara LS: Interaction between Ataxin-2 Binding Protein 1 and Cubitus-interruptus during wing development in Drosophila. Dev Biol; 2010 May 15;341(2):389-99
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  • Here we report that CG32062, the Drosophila homologue of Ataxin-2 Binding Protein 1 (dA2BP1), functions as a cofactor of Ci to specify intervein region between L3 and L4 veins of the adult wing.

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20226779.001).
  • [ISSN] 1095-564X
  • [Journal-full-title] Developmental biology
  • [ISO-abbreviation] Dev. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CG32062 protein, Drosophila; 0 / DNA-Binding Proteins; 0 / Drosophila Proteins; 0 / RNA-Binding Proteins; 0 / Transcription Factors; 0 / ci protein, Drosophila; 0 / knot protein, Drosophila
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93. Hopkins ND, Green DJ, Tinken TM, Sutton L, McWhannell N, Thijssen DH, Cable NT, Stratton G, George K: Does conduit artery diameter vary according to the anthropometric characteristics of children or men? Am J Physiol Heart Circ Physiol; 2009 Dec;297(6):H2182-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Arterial measurements are commonly undertaken to assess acute and chronic adaptations to exercise.
  • [MeSH-minor] Absorptiometry, Photon. Adolescent. Adult. Age Factors. Child. Empirical Research. Female. Humans. Least-Squares Analysis. Linear Models. Male. Middle Aged. Models, Cardiovascular. Ultrasonography, Doppler. Young Adult

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  • (PMID = 19837946.001).
  • [ISSN] 1522-1539
  • [Journal-full-title] American journal of physiology. Heart and circulatory physiology
  • [ISO-abbreviation] Am. J. Physiol. Heart Circ. Physiol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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94. Paolini V, Prevot F, Dorchies P, Hoste H: Lack of effects of quebracho and sainfoin hay on incoming third-stage larvae of Haemonchus contortus in goats. Vet J; 2005 Sep;170(2):260-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The effects of tannins on adult populations of Haemonchus contortus, Trichostrongylus colubriformis and Teladorsagia circumcincta in goats are characterised mainly by a decrease in egg excretion without any significant changes in worm number.
  • In contrast, the impact of tannins on T. colubriformis or T. circumcincta third-stage larvae (L3) is associated with a significant reduction in worm establishment.
  • The objective of the present study was to examine the effects of quebracho extract tannins on H. contortus L3.
  • All kids received 1500 L3 H. contortus on D0, D1 and D2.

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  • (PMID = 16129346.001).
  • [ISSN] 1090-0233
  • [Journal-full-title] Veterinary journal (London, England : 1997)
  • [ISO-abbreviation] Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anthelmintics; 0 / Plant Extracts; 0 / Tannins
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95. Zhuo X, Hu J, Li B, Liu J, Wang X, Xu D: [Effectiveness comparison of two surgical procedures on lumbar disc protrusion]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2010 Aug;24(8):908-12
MedlinePlus Health Information. consumer health - Herniated Disk.

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  • In group A, there were 51 males and 42 females with an average age of 32.3 years (range, 18-47 years); there were 23 cases of protrusion, 52 cases of prolapse, and 18 cases of sequestration with an average disease duration of 8.5 months (range, 1-18 months), including 8 cases at L2,3 level, 11 cases at L3,4 level, 35 cases at L4,5 level, and 39 cases at L5, S1 level.
  • In group B, there were 81 males and 67 females with an average age of 31.8 years (range, 16-50 years); there were 37 cases of protrusion, 85 cases of prolapse, and 26 cases of sequestration with an average disease duration of 9.3 months (range, 1-20 months), including 9 cases at L2,3 level, 15 cases at L3,4 level, 63 cases at L4,5 level, and 61 cases at L5, S1 level.
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Microsurgery. Middle Aged. Treatment Outcome. Young Adult

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  • (PMID = 20839433.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] China
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96. Dang H, Zhao M, Yan Y, Liu J, Zhang J, Xu S, Luo B: [Clinical diagnosis and treatment of multiple level thoracolumbar spinal fractures]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2008 Dec;22(12):1441-4
MedlinePlus Health Information. consumer health - Spine Injuries and Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • One fracture was located at T2, 1 at T3, 1 at T10, 4 at T11, 6 at T12, 5 at L1, at L2, 7 at L3, 5 at L4, and 2 at L15, with a total of 35 segments including 26 segments with unstable fractures and 9 segments with stable compression fractures.
  • [MeSH-minor] Adult. Bone Screws. Female. Fracture Fixation, Internal. Humans. Male. Middle Aged

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  • (PMID = 19137885.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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97. Reinhold M, Knop C, Beisse R, Audigé L, Kandziora F, Pizanis A, Pranzl R, Gercek E, Schultheiss M, Weckbach A, Bühren V, Blauth M: Operative treatment of 733 patients with acute thoracolumbar spinal injuries: comprehensive results from the second, prospective, Internet-based multicenter study of the Spine Study Group of the German Association of Trauma Surgery. Eur Spine J; 2010 Oct;19(10):1657-76
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Operative treatment of 733 patients with acute thoracolumbar spinal injuries: comprehensive results from the second, prospective, Internet-based multicenter study of the Spine Study Group of the German Association of Trauma Surgery.
  • The second, internet-based multicenter study (MCSII) of the Spine Study Group of the German Association of Trauma Surgery (Deutsche Gesellschaft für Unfallchirurgie) is a representative patient collection of acute traumatic thoracolumbar (T1-L5) injuries.
  • 65% of patients with thoracic (T1-T10) and 57% with lumbar spinal (L3-L5) injuries were treated with a single posterior approach (POSTERIOR).
  • In conclusion, comprehensive data of a large patient population with acute thoracolumbar spinal injuries has been obtained and analyzed with this prospective internet-based multicenter study.
  • [MeSH-minor] Acute Disease. Adolescent. Adult. Aged. Comorbidity. Female. Germany / epidemiology. Humans. Male. Middle Aged. Prospective Studies. Severity of Illness Index. Spinal Fractures / diagnosis. Spinal Fractures / epidemiology. Spinal Fractures / surgery. Young Adult

  • MedlinePlus Health Information. consumer health - Spine Injuries and Disorders.
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  • (PMID = 20499114.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2989217
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98. Zagra A, Giudici F, Minoia L, Corriero AS, Zagra L: Long-term results of pediculo-body fixation and posterolateral fusion for lumbar spondylolisthesis. Eur Spine J; 2009 Jun;18 Suppl 1:151-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The slipped vertebra was L5 in 57 cases (92%), L4 in 2 cases (3.2%), L3 in 1 case (1.6%), combined L4 and L5 in 2 cases (3.2%).
  • The fusion area was L5-S1 in 53 cases (85.5%), L3-L4 in 1 case (1.6%), L4-S1 in 8 cases (12.9%).
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Screws / standards. Bone Screws / statistics & numerical data. Bone Screws / trends. Decompression, Surgical / instrumentation. Decompression, Surgical / methods. Female. Humans. Internal Fixators / standards. Internal Fixators / statistics & numerical data. Internal Fixators / trends. Intervertebral Disc / pathology. Intervertebral Disc / radiography. Intervertebral Disc / surgery. Laminectomy / instrumentation. Laminectomy / methods. Low Back Pain / etiology. Male. Middle Aged. Outcome Assessment (Health Care). Postoperative Complications / etiology. Postoperative Complications / pathology. Postoperative Complications / physiopathology. Retrospective Studies. Spinal Canal / pathology. Spinal Canal / radiography. Spinal Canal / surgery. Time. Treatment Outcome. Young Adult. Zygapophyseal Joint / pathology. Zygapophyseal Joint / surgery

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  • (PMID = 19444490.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2899605
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99. Kuczkowski KM, Chandra S: Maternal satisfaction with single-dose spinal analgesia for labor pain in Indonesia: a landmark study. J Anesth; 2008;22(1):55-8
Hazardous Substances Data Bank. MORPHINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All 62 parturients received single-dose spinal anesthesia with a 27-gauge pencil-point needle at either the L3-4 or L4-5 intervertebral interspace, with a combination of bupivacaine, 2.5 mg; morphine, 0.25 mg; and clonidine, 45 microg.
  • [MeSH-minor] Adolescent. Adult. Analgesics / administration & dosage. Benchmarking. Bupivacaine / administration & dosage. Clonidine / administration & dosage. Female. Humans. Indonesia. Morphine / administration & dosage. Pain Measurement. Patient Satisfaction. Pregnancy. Treatment Outcome

  • Hazardous Substances Data Bank. CLONIDINE .
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  • (PMID = 18306015.001).
  • [ISSN] 0913-8668
  • [Journal-full-title] Journal of anesthesia
  • [ISO-abbreviation] J Anesth
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Analgesics; 76I7G6D29C / Morphine; MN3L5RMN02 / Clonidine; Y8335394RO / Bupivacaine
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100. Gallagher S, Marras WS, Litsky AS, Burr D, Landoll J, Matkovic V: A comparison of fatigue failure responses of old versus middle-aged lumbar motion segments in simulated flexed lifting. Spine (Phila Pa 1976); 2007 Aug 1;32(17):1832-9
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  • METHODS: Each lumbosacral spine was dissected into 3 motion segments (L1-L2, L3-L4, and L5-S1).
  • [MeSH-minor] Adult. Age Factors. Aged. Aged, 80 and over. Cadaver. Cohort Studies. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Proportional Hazards Models. Range of Motion, Articular. Risk Assessment. Risk Factors. Time Factors. Weight-Bearing






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