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1. Enright P: Check the FEV1 for all adult smokers, even patients without respiratory symptoms. Prim Care Respir J; 2010 Jun;19(2):91-2
MedlinePlus Health Information. consumer health - Smoking.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Check the FEV1 for all adult smokers, even patients without respiratory symptoms.
  • [MeSH-minor] Adult. Humans. Spirometry

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  • [CommentOn] Prim Care Respir J. 2010 Jun;19(2):163-9 [20514390.001]
  • (PMID = 20514389.001).
  • [ISSN] 1475-1534
  • [Journal-full-title] Primary care respiratory journal : journal of the General Practice Airways Group
  • [ISO-abbreviation] Prim Care Respir J
  • [Language] eng
  • [Publication-type] Comment; Editorial
  • [Publication-country] England
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2. Kalfoss MH, Low G, Molzahn AE: The suitability of the WHOQOL-BREF for Canadian and Norwegian older adults. Eur J Ageing; 2008 Mar;5(1):77

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The suitability of the WHOQOL-BREF for Canadian and Norwegian older adults.
  • The aim of this study was to examine the validity and reliability of the WHOQOL-BREF, a generic quality of life scale, among older people in Canada and Norway.
  • Very similar data from the Canadian and Norwegian Field Trial data (Canada <i>n</i> = 192; Norway, <i>n</i> = 469) were analyzed and compared.
  • Higher negatively skewed mean scores were found for all WHOQOL-BREF domains in Canada.
  • For both study samples, missing values were highest for the sex item from the social domain.
  • Ceiling effects were found (Canada <i>n</i> = 21; Norway <i>n</i> = 11) primarily among items in the physical and environmental domains.
  • In both study samples, a multitrait multimethod procedure indicated items correlated most strongly with their parent domains; however, equally appreciable correlations were observed between physical, psychological, and environmental items (<i>r</i> = 0.33-0.64; <i>p</i> < 0.01).
  • The social domain had the lowest internal consistency (<i>α</i> = 0.67 Canada, <i>α</i> = 0.55 Norway).
  • Confirmatory factor analyses (CFA) yielded marginal goodness-of-fit between the hypothesized WHOQOL-BREF measurement model and the sample data as well as differing patterns of domain misspecification.
  • Patterns of correlations (<i>p</i> < 0.01) of WHOQOL-BREF domains with WHOQOL-OLD facets, a global QOL item, the SF-12, and the geriatric depression scale provided evidence of convergent and divergent validity.
  • Domain scores also significantly discriminated between health and unhealthy populations and presence of morbidity.
  • Empirical support was found, in part, for the construct validity of the WHOQOL-BREF in older adults.
  • Despite some different patterns found in the CFA, possibly due to cultural or sampling differences, it appears that the instrument is reliable, valid, and facilitates cross-cultural comparisons.

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  • (PMID = 28798564.001).
  • [ISSN] 1613-9372
  • [Journal-full-title] European journal of ageing
  • [ISO-abbreviation] Eur J Ageing
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Older adult / Quality of life / Reliability / Validity / WHOQOL–BREF
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3. Van Oyen H, Cox B, Demarest S, Deboosere P, Lorant V: Trends in health expectancy indicators in the older adult population in Belgium between 1997 and 2004. Eur J Ageing; 2008 Jun;5(2):137

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Trends in health expectancy indicators in the older adult population in Belgium between 1997 and 2004.

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  • (PMID = 28798568.001).
  • [ISSN] 1613-9372
  • [Journal-full-title] European journal of ageing
  • [ISO-abbreviation] Eur J Ageing
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Belgium / Disability free life expectancy / Health expectancy / Life expectancy
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4. Slowly rebuilding her life, the nurse jailed for a crime she did not commit. Nurs Stand; 2009 May 27;23(38):12-13

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The former nurse has spent a large part of her adult life preoccupied with prison - either the thought of it or its harsh reality - all because of a crime she did not commit.

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  • (PMID = 27996753.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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5. Slováček L, Slováčková B, Jebavý L, Pavlík V: Quality of Life in Adult Patients Treated with Peripheral Blood Progenitor Cell Transplantation: the Effect of Selected Psychosocial, Demographics and Health Aspects on Quality of Life: a Retrospective Analysis. Acta Medica (Hradec Kralove); 2007;50(2):119-124

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quality of Life in Adult Patients Treated with Peripheral Blood Progenitor Cell Transplantation: the Effect of Selected Psychosocial, Demographics and Health Aspects on Quality of Life: a Retrospective Analysis.
  • AIM: this retrospective study analyses the effect of selected psychosocial, demographics and health aspects on quality of life (QoL) in adult patients treated with peripheral blood progenitor cell transplantation (PBPCT).
  • The QoL in adult patients treated with PBPCT declines with increasing age and with the increasing number of associated diseases.
  • CONCLUSION: The global QoL in an adult patients treated with PBPCT is on a good level.

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  • (PMID = 28949911.001).
  • [ISSN] 1211-4286
  • [Journal-full-title] Acta medica (Hradec Kralove)
  • [ISO-abbreviation] Acta Medica (Hradec Kralove)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Czech Republic
  • [Keywords] NOTNLM ; Cell transplantation / Peripheral blood progenitor / Quality of life / Quality of life questionnaires
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6. Introduction to medical-surgical nursing - fourth edition Adrianne Dill Linton Introduction to medical-surgical nursing - fourth edition Elsevier 1,424pp plus CD £54.99 978 1 4160 3114 7 1416031146 [Formula: see text]. Nurs Stand; 2009 Dec 02;24(13):30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This American textbook covers all aspects of the medical, surgical and psychiatric management of adult patients.

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  • (PMID = 28038575.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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7. Maher MM, Mansour AH: Study of Chronic Hepatopathy in Patients With Sickle Cell Disease. Gastroenterology Res; 2009 Dec;2(6):338-343

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A total of 170 adult patients with sickle cell syndrome were prospectively investigated.

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  • (PMID = 27990203.001).
  • [ISSN] 1918-2805
  • [Journal-full-title] Gastroenterology research
  • [ISO-abbreviation] Gastroenterology Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Keywords] NOTNLM ; Chronic hepatopathy / Sickle cell disease
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8. Sargent A: Lost generation. Nurs Stand; 2005 Mar 30;19(29):26

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lost generation.
  • : Despite what some students may think, those of us involved in nursing education are not all dinosaurs who have not practised since Florence Nightingale was a lass.
  • Many of us still practise either as part of our working day or as an adjunct to maintain our skills.
  • So, when we go into wards and other clinical areas, although we do so as educators, we still view the world as nurses.
  • There is something about being a nurse that you never lose.

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  • (PMID = 27985101.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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9. Lawton S: Assessing and treating adult patients with eczema. Nurs Stand; 2009 Jul 01;23(43):49-56

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessing and treating adult patients with eczema.

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  • (PMID = 27996824.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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10. Foster TC, Rani A, Kumar A, Cui L, Semple-Rowland SL: Viral Vector-mediated Delivery of Estrogen Receptor-α to the Hippocampus Improves Spatial Learning in Estrogen Receptor-α Knockout Mice. Mol Ther; 2008 Sep;16(9):1587-1593

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this study we show that lentiviral delivery of the gene encoding ER-α to the hippocampus of adult ER-α-knockout (ER-αKO) mice restores hippocampal responsiveness to estrogen and rescues spatial learning.

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  • [Copyright] Copyright © 2008 The American Society of Gene Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28189013.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Saalwachter Schulman A, Sawyer RG: The Safety of Percutaneous Endoscopic Gastrostomy Tube Placement in Patients With Existing Ventriculoperitoneal Shunts. JPEN J Parenter Enteral Nutr; 2005;29(6):442-444

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A retrospective chart review was performed that included all adult patients with existing VP shunts requiring PEG placement at a single university medical center over an approximate 9-year period from July 1995 to March 2004.
  • As the total number of adult patients requiring a PEG after VP shunt placement is low, multicenter studies should be carried out to better stratify this risk.

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  • (PMID = 28052746.001).
  • [ISSN] 0148-6071
  • [Journal-full-title] JPEN. Journal of parenteral and enteral nutrition
  • [ISO-abbreviation] JPEN J Parenter Enteral Nutr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Lord HK, Salter DM, MacDougall RH, Kerr GR: Is routine chest radiography a useful test in the follow up of all adult patients with soft tissue sarcoma? Br J Radiol; 2006 Oct;79(946):799-800
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is routine chest radiography a useful test in the follow up of all adult patients with soft tissue sarcoma?
  • Adult patients on routine follow up between 1994 and 2004 were identified and the notes of those with lung metastases reviewed.
  • [MeSH-minor] Adult. Follow-Up Studies. Humans. Neoplasm Recurrence, Local / radiography. Prognosis. Risk Factors

  • Genetic Alliance. consumer health - Soft tissue sarcoma.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
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  • (PMID = 16728411.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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13. de Jong G: A biophysical interpretation of temperature-dependent body size in Drosophila aldrichi and D. buzzatii. J Therm Biol; 2010 Feb;35(2):85-99

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Here, the temperature-size rule in Drosophila aldrichi and Drosophila buzzatii is investigated, using data on development rate and adult dry weight at nine temperatures.
  • The biophysical Sharpe-Schoolfield model for biological rates and its derivative model for adult weight yield detailed patterns for the two species' development rate, growth rate, and adult weight.

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  • [Copyright] Copyright © 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 28799917.001).
  • [ISSN] 0306-4565
  • [Journal-full-title] Journal of thermal biology
  • [ISO-abbreviation] J. Therm. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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14. Uno M, Oba-Shinjo SM, Wakamatsu A, Huang N, Avancini Ferreira Alves V, Rosemberg S, Pires de Aguiar PH, Leite C, Miura F, Marino J R, Scaff M, Nagahashi-Marie SK: Association of TP53 mutation, p53 overexpression, and p53 codon 72 polymorphism with susceptibility to apoptosis in adult patients with diffuse astrocytomas. Int J Biol Markers; 2006 Jan - Mar;21(1):50-57

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of TP53 mutation, p53 overexpression, and p53 codon 72 polymorphism with susceptibility to apoptosis in adult patients with diffuse astrocytomas.
  • The aim of this study was to analyze the possible association of TP53 mutation, p53 overexpression, and p53 codon 72 polymorphism with susceptibility to apoptosis in adult Brazilian patients with diffuse astrocytomas.

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  • (PMID = 28207094.001).
  • [ISSN] 1724-6008
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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15. Shepard RC, Talluto CC, Jacob G: Phase I study results of nanomolecular liposomal annamycin in refractory ALL. J Clin Oncol; 2009 May 20;27(15_suppl):7066

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The first-line therapy for adult AML has remained the same 7 + 3 that it was a generation ago.
  • CONCLUSIONS: Nanomolecular liposomal annamycin appears to be effective through its innate resistance to MDR even as a single agent in refractory adult ALL.

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  • (PMID = 27961442.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Matasar MJ, McCallen LN, Riedel ER, Ford JS, Oeffinger KC, Straus DJ: Late mortality and morbidity of patients with Hodgkin lymphoma treated in adulthood. J Clin Oncol; 2009 May 20;27(15_suppl):8547

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 8547 Background: Increased late mortality and morbidity have been observed among adult survivors of Hodgkin lymphoma (HL) treated in childhood, but are less well characterized for patients treated in adulthood.
  • METHODS: We investigated the late mortality and morbidity of adult patients treated at our center from 1975 to 2000.
  • These findings underscore the importance of efforts directed at prevention of and early intervention for late morbidity in adult survivors of HL.

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  • (PMID = 27960964.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Kohman L, Watson D, Herndon J 2nd, Eves N, Haithcock B, Loewen G, Jones L: CALGB 140803-Association between cardiorespiratory fitness and overall survival in operable lung cancer patients: Ancillary analysis of protocol 9238. J Clin Oncol; 2009 May 20;27(15_suppl):7518

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 7518 Background: Cardiorespiratory fitness is a well-established independent predictor of all-cause mortality in a broad range of adult populations.

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  • (PMID = 27963490.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Hauser KA, Karafa M, Seyidova-Khoshknabi D, Davis MP, Walsh D: Prevalence and risk factors of vitamin D insufficiency in cancer. J Clin Oncol; 2009 May 20;27(15_suppl):9581

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Electronic medical records of all adult solid tumor patients treated at The Cleveland Clinic in 2006-2007 were reviewed.

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  • (PMID = 27963701.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Cunningham SC, Spinoulas A, Carpenter KH, Wilcken B, Kuchel PW, Alexander IE: AAV2/8-mediated Correction of OTC Deficiency Is Robust in Adult but Not Neonatal Spf&lt;sup&gt;ash&lt;/sup&gt; Mice. Mol Ther; 2009 Aug;17(8):1340-1346

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] AAV2/8-mediated Correction of OTC Deficiency Is Robust in Adult but Not Neonatal Spf<sup>ash</sup> Mice.
  • In this study, we investigated metabolic correction in neonatal and adult male OTC-deficient Spf<sup>ash</sup> mice following adeno-associated virus (AAV)2/8-mediated delivery of the murine OTC complementary DNA under the transcriptional control of a liver-specific promoter.
  • Substantially supraphysiological levels of OTC enzymatic activity were readily achieved in both adult and neonatal mice following a single intraperitoneal (i.p.) injection, with metabolic correction in adults being robust and life-long.

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  • [Copyright] Copyright © 2009 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28160908.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Grinshpun A, Condiotti R, N Waddington S, Peer M, Zeig E, Peretz S, Simerzin A, Chou J, Pann CJ, Giladi H, Galun E: Neonatal Gene Therapy of Glycogen Storage Disease Type Ia Using a Feline Immunodeficiency Virus-based Vector. Mol Ther; 2010 Sep;18(9):1592-1598

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Previously, we have shown that these vectors are capable of integrating stably into hepatocyte cell lines and adult murine livers and lead to long-term transgene expression.

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  • [Copyright] Copyright © 2010 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28178467.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. D'Olimpio JT, Chasen MR, Sharma R, Diego M, Gullo V, MacDonald N: Phase II study of AVR118 in the management of cancer related anorexia/cachexia. J Clin Oncol; 2009 May 20;27(15_suppl):e20631

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Eligible adult patients received 4.0 ml of AVR118 subcutaneous daily injections.

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  • (PMID = 27961581.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Goldman S, Coiffier B, Reiter A, Younes A, Cairo MS, International TLS Expert Panel: A medical decision tree for the prophylaxis (P) and treatment (T) of tumor lysis syndrome (TLS): An international TLS consensus panel. J Clin Oncol; 2009 May 20;27(15_suppl):e17575

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: We convened an international panel (N = 17) of experts in pediatric and adult hematological malignancies and solid tumors (ST) to develop a medical decision tree for the P and T of TLS based on the risk classification (low, medium, high) and management recommendations of Coiffier et al (J Clin Oncol.

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  • (PMID = 27963935.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Pestina TI, Hargrove PW, Jay D, Gray JT, Boyd KM, Persons DA: Correction of Murine Sickle Cell Disease Using γ-Globin Lentiviral Vectors to Mediate High-level Expression of Fetal Hemoglobin. Mol Ther; 2009 Feb;17(2):245-252

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adult erythroid cells have β-globin mRNA 3'-UTR-binding proteins that enhance β-globin mRNA stability and we postulated this design might enhance γ-globin expression.

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  • [Copyright] Copyright © 2009 The American Society of Gene Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28192693.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Hafeez M, Shaharyar A, Zia N, Rasheed H: A phase II feasibility study of cytarabine and idarubicin combination in relapsed or refractory adult acute lymphoblastic leukemia. J Clin Oncol; 2009 May 20;27(15_suppl):e18002

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A phase II feasibility study of cytarabine and idarubicin combination in relapsed or refractory adult acute lymphoblastic leukemia.
  • : e18002 Background: Most patients with adult ALL eventually relapse.
  • CONCLUSIONS: The regimen of cytrarabine and idarubicin is feasible and sufficiently effective in relapsed or refractory adult ALL with manageable toxicity.

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  • (PMID = 27964000.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Lonetti A, Iacobucci I, Ferrari A, Messina M, Cilloni D, Soverini S, Papayannidis C, Baccarani M, Foà R, Martinelli G: Expression of different isoforms of the B-cell mutator activation-induced cytidine deaminase (AID) in BCR-ABL1-positive acute lymphoblastic leukemia (ALL) patients. J Clin Oncol; 2009 May 20;27(15_suppl):7049

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of different isoforms of the B-cell mutator activation-induced cytidine deaminase (AID) in BCR-ABL1-positive acute lymphoblastic leukemia (ALL) patients.
  • : 7049 Since the activation-induced cytidine deaminase (AID) enzyme can target non-immunoglobulin (Ig) genes and may even act as a genome-wide mutator, we investigated AID expression in BCR-ABL1-positive ALL and in chronic myeloid leukemia (CML) at the time of progression to blast crisis.
  • On the 61 de novo adult BCR-ABL1-positive ALL patients (pts), AID mRNA and protein were detected in 36 (59%); their expression correlated with BCR-ABL1 transcript levels and disappeared after treatment with tyrosine kinase inhibitors at the time of remission.
  • AID expression was also found in lymphoid blast crisis CML (50%), but not in myeloid lineage or in chronic phase CML.
  • Our findings show that BCR-ABL1-positive ALL cells aberrantly express different isoforms of AID that can act as mutator outside the Ig gene loci in promoting genetic instability in leukemia cells.

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  • (PMID = 27961429.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Jain M, Armstrong RJE, Elneil S, Barker RA: Transplanted Human Neural Precursor Cells Migrate Widely but Show no Lesion-Specific Tropism in the 6-Hydroxydopamine Rat Model of Parkinson's Disease. Cell Transplant; 2006 Aug;15(7):579-593

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transplanted Human Neural Precursor Cells Migrate Widely but Show no Lesion-Specific Tropism in the 6-Hydroxydopamine Rat Model of Parkinson's Disease.
  • Neural precursor cells might be ideal in this regard as in certain circumstances they have been shown to migrate widely following transplantation into the CNS.
  • The aim of this study was to investigate whether transplanted human expanded neural precursor cells (hENPs) could migrate to sites of established or evolving pathology in the adult brain using the 6-hydroxydopamine (6-OHDA) rat model of PD. hENPs were grafted into the striatum prior to, at the same time as, or after the animals received a 6-OHDA lesion to the medial forebrain bundle.
  • Therefore, the use of such cells to replace the range of neurons lost in PD is likely to require a deeper understanding of the migratory cues in the damaged adult brain and some manipulation of these cells prior to transplantation.

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  • (PMID = 28849971.001).
  • [ISSN] 1555-3892
  • [Journal-full-title] Cell transplantation
  • [ISO-abbreviation] Cell Transplant
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Cortex / Migration / Neural stem cells / Neural transplantation / Progenitor cells / Substantia nigra
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27. Ferron G, Aziza R, Delannes M, Filleron T, Marquès B, Labarre D, Labarre D, Chevreau C: Detection of local recurrences of limb soft-tissue sarcomas: Is magnetic resonance imaging (MRI) relevant? J Clin Oncol; 2009 May 20;27(15_suppl):10582

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of our study was to retrospectively evaluate the effectiveness of a MRI surveillance schedule performed in adult patients.
  • METHODS: 124 adult patients have been treated from 1996 to 2006 for a non-metastatic limb STS at our centre: 86 patients (70%) had clear resection margins (R0) and 111 patients (90%) received an adjuvant radiotherapy.

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  • (PMID = 27963876.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Pfister SM, Remke M, Benner A, Werft W, Mendrzyk F, Scheurlen W, Kulozik A, Lichter P, Korshunov A: Use of CDK6 oncogene amplification and 17q gain to predict poor clinical risk groups in adult medulloblastoma. J Clin Oncol; 2009 May 20;27(15_suppl):2030

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of CDK6 oncogene amplification and 17q gain to predict poor clinical risk groups in adult medulloblastoma.
  • METHODS: Array-CGH was performed for a total 34 adult medulloblastoma samples (>18 years) and results were compared with data from 101 pediatric patients.
  • Selected genomic regions were further investigated by FISH analysis in an independent cohort of 415 samples (112 adult and 303 pediatric).
  • All 146 adult patients received a standard treatment regimen consisting of tumor resection, irradiation of the neuroaxis with 36 Gy, a boost of 20-23 Gy to the posterior fossa, and eight cycles of vincristin, lomustine, and cisplatin.
  • RESULTS: Copy-number gains of chromosome 17q as well as high-level amplifications of CDK6 were identified as significant adverse prognostic markers in adult medulloblastoma.
  • Apart from one exception, CDK6 amplifications were only observed in adult patients (9% in adults versus 0.2 % in children), whereas amplifications of MYC or MYCN were significantly overrepresented in the pediatric cohort, but when present were also associated with dismal prognosis in adults.
  • Based on these results, we propose a molecular staging system for adult medulloblastoma: i) cases with oncogene amplification (10% of cases, 5-year OS = 0%);.
  • CONCLUSIONS: We report on the largest cohort of adult medulloblastoma investigated for genomic imbalances to date.
  • We propose a model for the molecular risk stratification of adult medulloblastoma comprising three distinct genomic risk groups with significantly different survival and tumor biology.

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  • (PMID = 27964634.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Sengupta N, Caballero S, Sullivan SM, Chang LJ, Afzal A, Li Calzi S, Kielczewski JL, Prabarakan S, Ellis EA, Moldovan L, Moldovan NI, Boulton ME, Grant MB: Regulation of Adult Hematopoietic Stem Cells Fate for Enhanced Tissue-specific Repair. Mol Ther; 2009 Sep;17(9):1594-1604

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regulation of Adult Hematopoietic Stem Cells Fate for Enhanced Tissue-specific Repair.
  • : The ability to control the differentiation of adult hematopoietic stem cells (HSCs) would promote development of new cell-based therapies to treat multiple degenerative diseases.

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  • [Copyright] Copyright © 2009 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28178547.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Bloomfield CD: Importance of genetic heterogeneity in curing adult acute leukemia (AL). J Clin Oncol; 2009 May 20;27(15_suppl):s1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Importance of genetic heterogeneity in curing adult acute leukemia (AL).
  • : s1 Forty-five years ago adult AL was incurable.
  • Publication of the French-American-British classification 34 years ago resulted in acceptance that morphology and cytochemistry separated AL into two different diseases, acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), that required separate treatment.
  • The most striking example of increased curability of AL is acute promyelocytic leukemia, in which targeted therapy combined with chemotherapy has increased survival from a 2-week median to an 80% cure rate.
  • Among adult de novo AML 40%-45% are cytogenetically normal (CN); the striking molecular heterogeneity of CN-AML is now being recognized and promises to allow individualized approaches that improve substantially upon the current cure rate of 40%.
  • In adult ALL the major adverse subgroup has a Philadelphia chromosome (PH+).
  • New approaches to studying the leukemia genome and epigenome should improve our understanding of AL heterogeneity, identify new therapeutic targets, and allow the cure of most patients.

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  • (PMID = 27962366.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Vry J, Martínez-Martínez P, Losen M, Bode GH, Temel Y, Steckler T, Steinbusch HW, Baets M, Prickaerts J: Low Current-driven Micro-electroporation Allows Efficient In Vivo Delivery of Nonviral DNA into the Adult Mouse Brain. Mol Ther; 2010 Jun;18(6):1183-1191

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low Current-driven Micro-electroporation Allows Efficient In Vivo Delivery of Nonviral DNA into the Adult Mouse Brain.
  • : Viral gene transfer or transgenic animals are commonly used technologies to alter gene expression in the adult brain, although these approaches lack spatial specificity and are time consuming.
  • We delivered plasmid DNA locally into the brain of adult C57BL/6 mice in vivo by voltage- and current-controlled electroporation.
  • In conclusion, low current-controlled electroporation is an excellent approach for electroporation in the adult brain, i.e., gene function can be influenced locally at a high level with no mortality and minimal tissue damage.

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  • [Copyright] Copyright © 2010 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28178496.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Rousková L, Hruška I, Filip S: Issues and Ethical Problems of Stem Cell Therapy - Where is Hippocrates? Acta Medica (Hradec Kralove); 2008;51(2):121-126

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Issues and Ethical Problems of Stem Cell Therapy - Where is Hippocrates?
  • Stem cells and their therapeutic use present many questions associated with ethical problems in medicine.
  • There is great effort on the part of physicians to help millions of patients while there are ethical problems with the use of new methods and technologies and all of these are affected by economic and political influences.
  • How will the current generation deal with these problems?
  • Medicine, in this begard, is experiencing a stormy evolution of human culture in the relationships between disease, patient and doctor.
  • Philosophy approaches the same juncture of human culture, but seemingly from the other side.
  • Both disciplines are facing a great problem: How to unite the content of current human morality and the desire for health?
  • Both philosophers and physicians perceive this deficit in human culture as it does not provide immediately usable normatives, which the living generation of healthy and ill is waiting for.
  • It may be said that medicine, as many times before, has reached a stage where it cannot rely only on the proved axiologic values from the past, ethical normatives or cultivated moral sense of its subjects.
  • Medicine has no other alternative than to take an active part in resolution of interdisciplinary problems originating from philosophic-biologic or philosophic-medical inquiries of axiologic, ethical, and moral issues.
  • Our paper indicates some ways of the search in forming ethical principles of the stem-cell therapy from the view of biologists and physicians.
  • New ways are recommended in theoretical-methodological interdisciplinary research, especially, in theoretical and experimental biology, and theoretical and clinical medicine, as well as philosophy.
  • In this paper important ethical problems are pointed out in order to find answers to some key problems connected with cell therapy and the use of stem cells.

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  • (PMID = 28550841.001).
  • [ISSN] 1211-4286
  • [Journal-full-title] Acta medica (Hradec Kralove)
  • [ISO-abbreviation] Acta Medica (Hradec Kralove)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Czech Republic
  • [Keywords] NOTNLM ; Adult stem cells / Cloning / Embryo / Ethical issue / Stem cell therapy / Stem cells
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33. Bonini A, Tieghi A, Gamberi B, Imovilli A, Carbonelli C, Spaggiari L, Gugliotta L: Caspofungin for invasive aspergillosis: A single-centre prospective study. J Clin Oncol; 2009 May 20;27(15_suppl):e20618

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Since 2004 we began a prospective study with the administration of Caspo as first line therapy in 63 consecutive adult neutropenic pts.
  • The diagnoses were: leukemia 44, myeloma 3, lymphoma 16; the disease's phases were: new onset 24, remission 16, relapse 23.

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  • (PMID = 27961616.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Tao X, Sood AK, Deavers MT, Schmeler KM, Nick AM, Coleman RL, Gershenson DM, Brown J: Antiangiogenic therapy for granulosa cell tumors of the ovary. J Clin Oncol; 2009 May 20;27(15_suppl):5574

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of these, 7 had adult granulosa cell tumors (GCT) and one had a juvenile GCT.

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  • (PMID = 27962607.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Cabanillas ME, Waguespack SG, Bronstein Y, Williams M, Feng L, Sherman SI, Busaidy NL: Treatment (tx) with tyrosine kinase inhibitors (TKIs) for patients (pts) with differentiated thyroid cancer (DTC): The M. D. Anderson Cancer Center (MDACC) experience. J Clin Oncol; 2009 May 20;27(15_suppl):6060

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Adult pts with a diagnosis of DTC treated with single agent sorafenib (SOR) or sunitinib (SUN), and who had a baseline and at least 1 follow-up (f/u) scan after 3 months (mos) of therapy, were included.

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  • (PMID = 27961926.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Puska PM, Tarkkanen AH: Transscleral red laser cyclophotocoagulation for the treatment of therapy-resistant inflammatory glaucoma. Eur J Ophthalmol; 2007 Jul-Aug;17:550-553

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among adult patients this was achieved in 85%, among children in 54%.

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  • (PMID = 28221549.001).
  • [ISSN] 1724-6016
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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37. Ay MR, Sarkar S, Shahriari M, Sardari D, Zaidi H: Assessment of different computational models for generation of x-ray spectra in diagnostic radiology and mammography. Med Phys; 2005 Jun;32(6Part1):1660-1675

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this work, the x-ray spectra predicted by various computational models used in the diagnostic radiology and mammography energy range have been assessed by comparison with measured spectra and their effect on the calculation of absorbed dose and effective dose (ED) imparted to the adult ORNL hermaphroditic phantom quantified.
  • The MCNP4C-based Monte Carlo calculations showed there is no discernable discrepancy in the calculation of absorbed dose and ED in the adult ORNL hermaphroditic phantom when using different computational models for generating the x-ray spectra.

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  • [Copyright] © 2005 American Association of Physicists in Medicine.
  • (PMID = 28513954.001).
  • [ISSN] 2473-4209
  • [Journal-full-title] Medical physics
  • [ISO-abbreviation] Med Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Ancillary equipment / Computational models / Dosimetry / Electric measurements / Mammography / Molybdenum / Monte Carlo methods / Photons / Spectral properties / Transmission measurement / Treatment strategy / Tungsten / X-ray and EXAFS / X-ray spectra / diagnostic radiography / dosimetry / mammography / optimisation / phantoms / statistical analysis
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38. Udoh FV, Udoh PB: Hepatotoxicity of the Methanol Extract of Carica papaya. (Paw-Paw) Seeds in Wistar Rats. Pharm Biol; 2005;43(4):349-352

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tolerated doses of C. papaya. were estimated in acute toxicity studies and administered orally, single or repeated doses, for 30 days to adult male rats weighing between 190 and 200 g, which were divided into four groups of five rats per group.

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  • (PMID = 28925838.001).
  • [ISSN] 1744-5116
  • [Journal-full-title] Pharmaceutical biology
  • [ISO-abbreviation] Pharm Biol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Carica papaya / Wistar rats / hepatotoxicity / liver sections
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39. Keswani RN, Neven K, Semrad CE: Screening for Celiac Disease in Short Bowel Syndrome. Nutr Clin Pract; 2008 Feb;23(1):72-75

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Adult subjects with SBS were tested for celiac disease using immunoglobulin A (IgA) tissue transglutaminase (TTG) antibody and total IgA level.

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  • (PMID = 28056688.001).
  • [ISSN] 1941-2452
  • [Journal-full-title] Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
  • [ISO-abbreviation] Nutr Clin Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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40. Alexandrova K, Griesel C, Barthold M, Heuft HG, Ott M, Winkler M, Schrem H, Manns MP, Bredehornsp T, Net M, Vidal MMI, Kafert-Kasting S, Arseniev L: Large-Scale Isolation of Human Hepatocytes for Therapeutic Application. Cell Transplant; 2005 Nov;14(10):845-853

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • During the last decade, hepatocyte transplantation has been suggested as a safe and potentially effective clinical option for the treatment of acute or decompensating chronic liver failure as well as for hereditary liver disease.
  • No correlation between isolation efficiency and cold ischemia time or donor age was found within the adult organ donors.

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  • (PMID = 28849979.001).
  • [ISSN] 1555-3892
  • [Journal-full-title] Cell transplantation
  • [ISO-abbreviation] Cell Transplant
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Cell transplantation / GMP / Hepatocyte isolation / Steatosis
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41. Cortes JE, Khoury HJ, Corm S, Nicolini F, Schenk T, Jones D, Hochhaus A, Craig AR, Humphriss E, Kantarjian H, Omacetaxine 202 Study Group: Subcutaneous omacetaxine mepesuccinate in imatinib-resistant chronic myeloid leukemia (CML) patients (Pts) with the T315I mutation: Data from an ongoing phase II/III trial. J Clin Oncol; 2009 May 20;27(15_suppl):7008

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subcutaneous omacetaxine mepesuccinate in imatinib-resistant chronic myeloid leukemia (CML) patients (Pts) with the T315I mutation: Data from an ongoing phase II/III trial.
  • METHODS: Adult Pts with T315I+ CML following TKI failure received OM induction at 1.25 mg/m<sup>2</sup> subcutaneous (SC) twice daily (BID) for 14 days every 28 days followed by maintenance at 1.25 mg/m<sup>2</sup> SC BID for 7 days every 28 days (maintenance after at least one induction cycle and achievement of hematologic response).

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  • (PMID = 27961380.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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42. Necchi A, Colecchia M, Nicolai N, Mego M, De Giorgi U, Mikuz G, Sava T, Di Nicola M, Pastorino U, Salvioni R: Somatic malignant differentiation in adult male germ-cell tumors (GCTs): Preliminary evidences from the INTera database (International Project for Teratoma with Malignant Transformation). J Clin Oncol; 2009 May 20;27(15_suppl):e16013

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Somatic malignant differentiation in adult male germ-cell tumors (GCTs): Preliminary evidences from the INTera database (International Project for Teratoma with Malignant Transformation).

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  • (PMID = 27962924.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Bleyer A, Friedman S, Finnegan S, Montello M, Budd T, Anderson B, Trimble EL: Association of adolescent and young adult cancer treatment trial activity with a national mortality reduction benefit in the United States. J Clin Oncol; 2009 May 20;27(15_suppl):6605

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of adolescent and young adult cancer treatment trial activity with a national mortality reduction benefit in the United States.
  • : 6605 Background: Adolescent and young adult (AYA) cancer patients in the U.S. have had less mortality and survival improvement than have children or older adults with cancer.
  • Among 15-29 year-olds nearly all of the increased accrual occurred in patients with leukemia or lymphoma, in whom the ratio of the national death rate to SEER incidence fell below the projected linear regression for this ratio in each year during 2002-2005.
  • CONCLUSIONS: In the U.S., COG is now contributing more AYA patients to NCTT than any adult cooperative group, suggesting that the adult-treating groups and cancer centers have increased capability to increase AYA accrual and should complement the pediatric effort.
  • These favorable trends should encourage implementation of the clinical trial recommendations of the NCI Program Review Group in AYA Oncology ( http://planning.cancer.gov/disease/AYAO_PRG_Report_2006_FINAL.pdf ) that are being implemented in part by the LIVESTRONG Young Adult Alliance (Closing the Gap: A Strategic Plan).

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  • (PMID = 27961733.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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44. Lee CL, Wahnishe H, Sayre GA, Cho HM, Kim HJ, Hernandez-Pampaloni M, Hawkins RA, Dannoon SF, VanBrocklin HF, Itsara M, Weiss WA, Yang X, Haas-Kogan DA, Matthay KK, Seo Y: Radiation dose estimation using preclinical imaging with I124-metaiodobenzylguanidine (MIBG) PET. Med Phys; 2010 Sep;37(9):4861-4867

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Based on tabulated organ mass distributions for both mice and adult male human, preclinical pharmacokinetic data were extrapolated to their human-equivalent values.
  • RESULTS: The mean effective dose fromI124-MIBG using weighting factors from ICRP 103 to the adult male was estimated at 0.25 mSv/MBq.
  • In different age groups, effective doses using values from ICRP 103 were estimated as follows: Adult female: 0.34, 15-yr-old: 0.39 mSv/MBq, 10-yr-old: 0.58 mSv/MBq, 5-yr-old: 1.03 mSv/MBq, 1-yr-old: 1.92 mSv/MBq, and newborn: 3.75 mSv/MBq.
  • For comparison, the reported effective dose equivalent of I124-NaI for adult male (25% thyroid uptake, MIRD Dose Estimate Report No. 5) was 6.5 mSv/MBq.

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  • [Copyright] © 2010 American Association of Physicists in Medicine.
  • (PMID = 28524557.001).
  • [ISSN] 2473-4209
  • [Journal-full-title] Medical physics
  • [ISO-abbreviation] Med Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Anatomy / Cancer / Computed tomography / Dosimetry / Heart / Liver / Medical imaging / PET / Positron emission tomography / Positron emission tomography (PET) / Radioactivity / Registration / Tissues / dosimetry / image registration / iodine-124 / metaiodobenzylguanidine (MIBG) / neuroblastoma / positron emission tomography / tumours
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45. Zuo Z, Jones DM, Thomas DA, O'Brien S, Ravandi F, Kantarjian HM, Medeiros LJ, Luthra R, Chen SS: A nine-gene predictor of therapy response in adult Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ ALL). J Clin Oncol; 2009 May 20;27(15_suppl):7014

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A nine-gene predictor of therapy response in adult Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ ALL).
  • Expression of the selected genes was assessed using Applied Biosystems low density reverse transcription quantitative PCR (RT-qPCR) arrays in bone marrow (BM) samples from 27 adult Ph+ ALL patients treated with standard chemotherapy plus a tyrosine kinase inhibitor.
  • CONCLUSIONS: Using data-trimming of whole genome expression studies, we defined and validated a nine-gene signature that is an independent predictive marker for therapy response in adult Ph+ ALL patients.

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  • (PMID = 27961387.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Sharma AD, Julka PK, Rastogi A, Suri T, Rath GK, Sharma BN, Baliga VP: Assessment of efficacy, safety, and tolerability of aprepitant in adult patients with chemotherapy-induced vomiting. J Clin Oncol; 2009 May 20;27(15_suppl):e20729

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessment of efficacy, safety, and tolerability of aprepitant in adult patients with chemotherapy-induced vomiting.
  • The present study was undertaken to assess efficacy, safety, and tolerability of Aprepitant in adult patients with chemotherapy induced nausea and vomiting.
  • METHODS: The study was conducted as a prospective, multicenter, randomized, open label, single group, phase III study in adult patients with chemotherapy induced nausea and vomiting and patients admitted to hospital for any type of cancer.

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  • (PMID = 27962017.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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47. Javle MM, Xiong H, Reddy S, Bhosale P, Davis D, Varadhachary G, Fogelman D, Kaseb A, Wolff RA, Abbruzzese JL: Inhibition of mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: The results of two prospective phase II studies. J Clin Oncol; 2009 May 20;27(15_suppl):4621

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Inclusions: Adult patients with gemcitabine-refractory pancreatic cancer, ECOG PS 0-1, adequate laboratories and measurable disease.

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  • (PMID = 27964220.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Williams CK: HIV/AIDS pandemic (AP) in Africa: Chronicle of a missed opportunity. J Clin Oncol; 2009 May 20;27(15_suppl):e22235

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • HIV-1 was undetectable by IWB, while SWB revealed 2/204 HIV-1+ for countrywide SPR: ∼1.0; Western NBD: 1/100 (1.0); Western/Northern NBD: 1/184 (0.54): non-high risk Nigerians: 2/237 (0.84); FCSW: 0/46; celibates: 0/71, adult general Nigerian population (AGNP): ∼0.5-1.0, and translating to (∼240-480)x10<sup>3</sup> HIV-1+ AGNP.

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  • (PMID = 27964112.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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49. Gupta AA, Al-Hussaini H, Yu C, Griffin A, Tsung V, Stephens D, Blackstein M, Hogg D, Ferguson P, Wunder J: Clinical features, treatment, and outcome in 108 patients with localized, high-grade synovial sarcoma (SS). J Clin Oncol; 2009 May 20;27(15_suppl):10584

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Between 1986 and 2007, 93 adult (AP) and 15 pediatric (PP) patients were diagnosed with high grade, localized SS at 2 centres in Toronto.

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  • (PMID = 27963882.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. Italiano A, Delva F, Brouste V, Terrier P, Trassard M, Michels J, Collin F, Coindre J, Blay J, Bui B: Effect of adjuvant chemotherapy on survival in FNCLCC grade 3 soft tissue sarcomas: A multivariate analysis of the French Sarcoma Group database. J Clin Oncol; 2009 May 20;27(15_suppl):10504

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 10504 Background: The SMAC meta-analysis failed to demonstrate that adjuvant chemotherapy (AC) significantly improves overall survival (OS) in adult patients with localised resectable soft-tissue sarcoma (STS).

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  • (PMID = 27963693.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Giles FJ, O'Brien S, Rizzieri DA, Vey N, Krug U, Sekeres M, Jacobsen TF, Nilsson BI, Staudacher K: A phase II study with CP-4055 in patients with second salvage AML. J Clin Oncol; 2009 May 20;27(15_suppl):7047

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of this study was to assess efficacy and safety of CP-4055 when given as second salvage therapy to patients (pts) with acute myeloid leukemia (AML).
  • METHODS: Adult pts who received two previous chemotherapy regimens and who had refractory/relapsed AML (CR after first salvage therapy lasting less than 6 months) were enrolled.

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  • (PMID = 27961426.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Mohty M, Balere M, Socie G, Milpied N, Ifrah N, Harousseau JL, Michallet M, Blaise D, Esperou H, Yakoub-Agha I, SFGM-TC: Effect of antithymocyte globulins (ATG) as part of the myeloablative conditioning (MAC) regimen on the risk of severe graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (allo-SCT) from matched-unrelated donors (MUD). J Clin Oncol; 2009 May 20;27(15_suppl):7025

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The purpose of the study was to compare the incidence and severity of acute and chronic GVHD as well as overall outcome.
  • 171 adult patients with acute leukemia and MDS, for whom detailed allelic HLA typing (4 digits) was available, were included.
  • With a median follow-up of 30.3 (range, 2.6-68.1) months, grade 0-1 and 2-4 acute GVHD occurred in 74 (46%) and 88 patients (54%) respectively, with grade 3-4 acute GVHD being significantly lower in the ATG group (18% vs. 32%; p = 0.04).
  • In multivariate analysis, an HLA allelic mismatch and the non-use of ATG were associated with an increased risk of grade 3-4 acute GVHD (RR = 2.80, 95% CI, 1.5-5.3, p = 0.001; and RR = 2.4, 95% CI, 1.1-5.0, p = 0.02 respectively).

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  • (PMID = 27961398.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Choi JC, Chang JD, Seal B, Tangirala M, Mullins CD: Risk and cost of anthracycline-induced cardiotoxicity among breast cancer patients in the United States. J Clin Oncol; 2009 May 20;27(15_suppl):1037

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adult subjects (≥18) diagnosed with breast cancer, between January 1, 2002 to December 31, 2005, (index-period) were followed for 24 months.

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  • (PMID = 27961068.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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54. Demetri GD, Schuetze S, Blay J, Chawla S, von Mehren M, Casali P, Morris D, Bayever E, Alfaro V, LeCesne A: Long-term results of a randomized phase II study of trabectedin by two different dose and schedule regimens in patients with advanced liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide. J Clin Oncol; 2009 May 20;27(15_suppl):10509

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 10509 Background: This prospective, international randomized study evaluated two trabectedin dosing regimens [1.5 mg/m<sup>2</sup> 24-hour i.v. infusion once every 3 weeks (q3wk 24-h) vs. 0.58 mg/m<sup>2</sup> 3-hour i.v. infusion every week for 3 weeks of a 4-week cycle (qwk 3-h)] in adult patients (pts) with unresectable and/or metastatic liposarcoma or leiomyosarcoma following failure of at least prior anthracycline and ifosfamide chemotherapy.

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  • (PMID = 27963700.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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55. Klepin HD, Song EY, Geiger AM, Tooze JA, Foley KL: Influence of age on receipt of chemotherapy for adult Medicaid beneficiaries with metastatic colorectal cancer. J Clin Oncol; 2009 May 20;27(15_suppl):9548

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Influence of age on receipt of chemotherapy for adult Medicaid beneficiaries with metastatic colorectal cancer.

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  • (PMID = 27963615.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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56. Camacho F, Mullins CD, Joish V, Choi J: Common head and neck cancer treatment pathways and associated costs in the U.S. commercial managed care population. J Clin Oncol; 2009 May 20;27(15_suppl):e17001

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adult subjects (≥18) diagnosed with HNC between January 1, 2006, to December 31, 2006, (index-period) were identified based on a pre-selected ICD-9-CM codes.

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  • (PMID = 27961649.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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57. Nieder C, Pawinski A, Haukland E, Dokmo R, Philippi I, Dalhaug A: Estimating the need for palliative external beam radiotherapy in adult cancer patients. J Clin Oncol; 2009 May 20;27(15_suppl):e20599

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Estimating the need for palliative external beam radiotherapy in adult cancer patients.
  • METHODS: Prospective collection of data on palliative RT in adult cancer patients during a 12 months period in 2007/2008 in a well defined region of Norway.

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  • (PMID = 27961157.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Olofsson S, Dahl O, Jerkeman M, Cohn-Cedermark G, Klepp O, Stierner U, Törnblom M, Wahlqvist R, Cavallin-Ståhl E, SWENOTECA: Individualized intensification of treatment based on tumor marker decline in metastatic nonseminomatous germ cell testicular cancer (NSGCT): A report from the Swedish Norwegian Testicular Cancer Group, SWENOTECA. J Clin Oncol; 2009 May 20;27(15_suppl):5015

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 5015 Background: From July 1995 to December 2003, 602 adult patients from Sweden and Norway with metastatic testicular NSGCT were included in a population-based multicenter SWENOTECA protocol with strict guidelines for staging, treatment and follow-up.

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  • (PMID = 27962902.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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59. Virgo KS, Fedewa SA, Chen AY, Stewart AK, Flanders WD, Ward EM: Hospital characteristics associated with surgery for non-small cell lung cancer. J Clin Oncol; 2009 May 20;27(15_suppl):6543

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: All adult patients ages 19-104 diagnosed with an invasive initial primary early stage (TNM I-II) NSCLC during 2003-2005 were selected from the National Cancer Data Base (NCDB).

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  • (PMID = 27964059.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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60. Kesserwan C, Sokolic R, Cowen E, Garabedian E, Pittaluga S, Baird K, López-Terrada D, Issekutz A, Bridge J, Wayne A, Candotti F: Dermatofibrosarcoma protuberans (DFSP) in six patients with ADA-SCID. J Clin Oncol; 2009 May 20;27(15_suppl):10570

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A storiform pattern was only noticed in one adult patient.

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  • (PMID = 27963775.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Pink D, Rahm J, Schoeler D, Schoenknecht TM, Reichardt P: Activity of paclitaxel in radiation induced and other secondary angiosarcomas. J Clin Oncol; 2009 May 20;27(15_suppl):10578

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 10578 Background: Angiosarcomas (AS) represent 1-2% of adult soft tissue sarcomas and can arise anywhere in the body.

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  • (PMID = 27963758.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Olmos D, Allred A, Sharma R, Brunetto A, Smith D, Murray S, Barker D, Taegtmeyer A, de Bono J, Blagden S: Phase I first-in-human study of the polo-like kinase-1 selective inhibitor, GSK461364, in patients with advanced solid tumors. J Clin Oncol; 2009 May 20;27(15_suppl):3536

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Adult patients (pts) with relapsed/refractory advanced solid tumors with performance status of 0-2 and adequate organ function were eligible.

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  • (PMID = 27961338.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Pantaleo M, Astolfi A, Di Battista M, Paterini P, Santini D, Catena F, Nannini M, Saponara M, Lolli C, Maleddu A, Biasco G: The potential role of IGF1r in young adult patients with gastroinetstinal stromal tumor (GIST). J Clin Oncol; 2009 May 20;27(15_suppl):10562

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The potential role of IGF1r in young adult patients with gastroinetstinal stromal tumor (GIST).
  • The young adult patients had a strongly different molecular background in comparison to the other older ones.

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  • (PMID = 27963813.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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64. Chen B, Mahmud F, Mangel J, Vujovic O, Rieder M, Zelcer S: Impaired endothelial function in Hodgkin lymphoma survivors receiving mediastinal radiation. J Clin Oncol; 2009 May 20;27(15_suppl):e19526

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These differences were not explained by alterations in lipoproteins or hsCRP, however activity scores were significantly lower in HLS compared with young adult controls (2.01 ± 1.1 vs. 3.6 ± 1.2 hrs daily, p=0.02).

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  • (PMID = 27960923.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Amess JA, O'neill W, Giollariabhaigh N, Dytrych JK: A six-month audit of the isolation of Fusobacterium necrophorum from patients with sore throat in a district general hospital. Br J Biomed Sci; 2007 Jan;64(2):63-65

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The results presented here indicate that F. necrophorum is second to group A haemolytic streptococci as a cause of sore throat, especially in the young adult, and introduction of routine culture should be considered.

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  • (PMID = 28696888.001).
  • [ISSN] 0967-4845
  • [Journal-full-title] British journal of biomedical science
  • [ISO-abbreviation] Br. J. Biomed. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Fusobacterium necrophorum / Pharyngitis / Streptococcal infections
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66. Bukhari MH, Byron E, Strosberg JR, Nasir NA, Henderson-Jackson E, Bui M, Hakam A, Domenico C, Kvols L, Nasir A: Primary gastroenteropancreatic poorly differentiated neuroendocrine carcinoma: Clinico-pathologic analysis of 68 cases. J Clin Oncol; 2009 May 20;27(15_suppl):e15616

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Under an IRB-approved protocol, clinico-pathologic data were collected on 68 adult patients with GEP-PDNECA who had undergone biopsy / resection at MCC or outside institution.

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  • (PMID = 27962728.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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67. Pemmaraju N, Kantarjian H, Ravandi F, O'Brien S, Wierda W, Thomas D, Garcia-Manero G, Borthakur G, Pierce S, Cortes J: Acute myeloid leukemia (AML) in adolescents and young adults (AYA): The M. D. Anderson Cancer Center (MDACC) experience. J Clin Oncol; 2009 May 20;27(15_suppl):7051

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acute myeloid leukemia (AML) in adolescents and young adults (AYA): The M. D. Anderson Cancer Center (MDACC) experience.
  • RESULTS: Among 3,934 adult AML pts treated during this period, 163 pts (4%) were AYA with median age of 19 yrs.
  • This cohort included 27 (17%) pts with Core Binding Factor (CBF)-AML [inv(16), t(8:21)] and 19 pts (12%) with acute promyelocytic leukemia (APL).
  • Outcome is better for pts with CBF leukemia (3 yr survival 56%, sustained CR 49%) and APL (3 yr survival 51%, sustained CR 36%) compared to other AML (3 yr survival 28%, sustained CR 24%).

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  • (PMID = 27961415.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Sudol KL, Mastrangelo MA, Narrow WC, Frazer ME, Levites YR, Golde TE, Federoff HJ, Bowers WJ: Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease. Mol Ther; 2009 Dec;17(12):2031-2040

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The intrabodies, one with an endoplasmic reticulum (ER) targeting signal and one devoid of a targeting sequence, were assessed in cells harboring a doxycycline (Dox)-regulated mutant human amyloid precursor protein Swedish mutant (hAPP<sup>swe</sup>) transcription unit for their abilities to prevent Aβ peptide egress.
  • Adeno-associated virus (AAV) vectors expressing the engineered intrabodies were administered to young adult 3xTg-AD mice, a model that develops amyloid and Tau pathologies, prior to the initial appearance of intraneuronal Aβ.

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  • [Copyright] Copyright © 2009 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28178451.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Ganesan P, Raina V, Kumar R: A phase II pilot study of valproic acid in relapsed/refractory chronic lymphocytic leukemia. J Clin Oncol; 2009 May 20;27(15_suppl):7081

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A phase II pilot study of valproic acid in relapsed/refractory chronic lymphocytic leukemia.
  • : 7081 Background: Valproic acid (VA) has demonstrated cell-kill by triggering pro-apoptotic pathways in chronic lymphocytic leukemia (CLL) in preclinical studies.
  • METHODS: Adult patients with CLL diagnosed by the NCI-WG criteria who had received at least one previous fludarabine-based therapy and subsequently progressed or relapsed with ECOG performance status (PS) ≤3 and normal organ functions were included.

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  • (PMID = 27961474.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Dodiya HB, Bjorklund T, Stansell Iii J, Mandel RJ, Kirik D, Kordower JH: Differential Transduction Following Basal Ganglia Administration of Distinct Pseudotyped AAV Capsid Serotypes in Nonhuman Primates. Mol Ther; 2010 Mar;18(3):579-587

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Six intact young adult cynomolgus monkeys received a single 10 µl injection of AAV2/1-GFP, AAV2/5-GFP, or AAV2/8-GFP pseudotyped vectors into the caudate nucleus and putamen bilaterally in a pattern that resulted in each capsid serotype being injected into at least four striatal sites.

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  • [Copyright] Copyright © 2010 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28182881.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Leggas M, Horn J, Tsakalozou E, Moscow JA, Fields SZ, Houchins JC, Eckardt JR, DeSimone P, Kee BK, Rinehart JJ, Arnold SM: Pharmacokinetics (PK) of the highly lipophilic and blood stable camptothecin AR-67 (7-t-butyldimethylsilyl-10- hydroxycamptothecin) in adult patients with solid malignancies. J Clin Oncol; 2009 May 20;27(15_suppl):2546

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacokinetics (PK) of the highly lipophilic and blood stable camptothecin AR-67 (7-t-butyldimethylsilyl-10- hydroxycamptothecin) in adult patients with solid malignancies.

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  • (PMID = 27961862.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Faderl S, Thomas DA, Gandhi V, Huang X, Borthakur G, O'Brien S, Ravandi F, Plunkett W, Bretz JL, Kantarjian HM: Results of a phase I study of clofarabine (CLO) plus cyclophosphamide (CY) in adult patients (pts) with relapsed and/or refractory acute lymphoblastic leukemia (ALL). J Clin Oncol; 2009 May 20;27(15_suppl):7020

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Results of a phase I study of clofarabine (CLO) plus cyclophosphamide (CY) in adult patients (pts) with relapsed and/or refractory acute lymphoblastic leukemia (ALL).
  • Single agent CLO in adult ALL was less active so that combinations of CLO with other active agents are pursued.
  • Twenty-one pts had pre-B ALL, 5 pts pre-T/T ALL, 1 pt mature B ALL, and 3 pts biphenotypic acute leukemias.

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  • (PMID = 27961382.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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73. Ferring D, Michels T, Boll T, Filipp SH: Emotional relationship quality of adult children with ageing parents: on solidarity, conflict and ambivalence. Eur J Ageing; 2009 Dec;6(4):253

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Emotional relationship quality of adult children with ageing parents: on solidarity, conflict and ambivalence.
  • Based on this assumption the present study was performed to identify different types of emotional relationship quality of middle-aged adult children with their ageing parents.
  • This was done by cluster analytic procedures in a sample of 1,208 middle-aged adult children (482 men, 726 women).
  • Clusters differed significantly with respect to gender of adult child, willingness to support, expected parental support and overt conflicts.

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  • [Cites] Am Psychol. 1997 Apr;52(4):366-80 [9109347.001]
  • [Cites] J Gerontol. 1990 Jan;45(1):S12-20 [2295781.001]
  • [Cites] J Fam Psychol. 2003 Dec;17(4):472-87 [14640798.001]
  • [Cites] Psychol Aging. 2000 Jun;15(2):187-224 [10879576.001]
  • [Cites] J Gerontol B Psychol Sci Soc Sci. 2008 Nov;63(6):P362-71 [19092039.001]
  • (PMID = 28798609.001).
  • [ISSN] 1613-9372
  • [Journal-full-title] European journal of ageing
  • [ISO-abbreviation] Eur J Ageing
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Adult offspring / Emotions / Intergenerational relations / Parent–child relations / Taxonomies
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74. Nishida T, Takahashi T, Nakajima K, Tsujinaka T, Hirota S: KIT and PDGFRA mutations of gastrointestinal stromal tumor. J Clin Oncol; 2009 May 20;27(15_suppl):10560

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • WT are found in 3 juvenile GIST or 4 NF-1, and only 1 adult GIST showed WT.
  • Mutations in KIT and PDGFRA are specific for GIST and WT GIST is extremely rare in adult pts except NF-1.

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  • (PMID = 27963809.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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75. Metcalf JA, Ma X, Linders B, Wu S, Schambach A, Ohlemiller KK, Kovacs A, Bigg M, He L, Tollefsen DM, Ponder KP: A Self-inactivating γ-Retroviral Vector Reduces Manifestations of Mucopolysaccharidosis I in Mice. Mol Ther; 2010 Feb;18(2):334-342

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This report demonstrates that intravenous (i.v.) injection of a SIN γ-RV expressing canine IDUA from the liver-specific human α<sub>1</sub>-antitrypsin promoter into adult or newborn MPS I mice completely prevents biochemical abnormalities in several organs, and improved bone disease, vision, hearing, and aorta to a similar extent as was seen with administration of the LTR-intact vector to adults.

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  • [Copyright] Copyright © 2010 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28182939.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Li H, Lu Y, Witek RP, Chang LJ, Campbell-Thompson M, Jorgensen M, Petersen B, Song S: Ex Vivo Transduction and Transplantation of Bone Marrow Cells for Liver Gene Delivery of α1-Antitrypsin. Mol Ther; 2010 Aug;18(8):1553-1558

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : Adult stem cell-based gene therapy holds several unique advantages including avoidance of germline or other undesirable cell transductions.

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  • [Copyright] Copyright © 2010 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28178512.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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77. Iacobucci I, Storlazzi C, Lonetti A, Ferrari A, Messina M, Cilloni D, Papayannidis C, Baccarani M, Foà R, Martinelli G: IKZF1 (IKAROS) deletions as a prognostic marker in BCR-ABL1 positive acute lymphoblastic leukemia patients: A GIMEMA ALL WP Report. J Clin Oncol; 2009 May 20;27(15_suppl):11005

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] IKZF1 (IKAROS) deletions as a prognostic marker in BCR-ABL1 positive acute lymphoblastic leukemia patients: A GIMEMA ALL WP Report.
  • : 11005 Expression of BCR-ABL1 in hematopoietic stem cells can alone induce a chronic myeloid leukemia (CML) but cooperating oncogenic lesions are required for the generation of a blastic leukemia.
  • To identify oncogenic sub-microscopic lesions that cooperate with BCR-ABL1 to induce ALL, by high resolution single nucleotide polymorphism (SNP) arrays (250K NspI and SNP 6.0, Affymetrix) we studied 106 patients (pts) with de novo adult BCR-ABL1-positive ALL.
  • The most frequent somatic copy number alteration was deletion on 7p12 of IKZF1 (68/106, 64%), which encodes the transcription factor Ikaros required for the earliest stages of lymphoid lineage commitment.

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  • (PMID = 27964054.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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78. Taylor DR, Fisher AN, Smith A, Watling M, Knight A, Gabrail NY: Pharmacokinetic and local tolerability profiles of three potential fentanyl nasal spray formulations developed for breakthrough cancer pain compared with oral transmucosal fentanyl citrate. J Clin Oncol; 2009 May 20;27(15_suppl):e20554

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: This phase I, open-label, crossover study was conducted in 18 healthy adult volunteers to compare the pharmacokinetic profiles of the three new nasal fentanyl formulations with oral transmucosal fentanyl citrate (OTFC).

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  • (PMID = 27961042.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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79. Nelson S: Oxygen therapy. Nurs Stand; 2009 Sep 02;23(52):59-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : This article updated my knowledge of domiciliary oxygen therapy for adult patients.

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  • (PMID = 27996729.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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80. Shah A, Tekriwal AK, Drummond PM, Woodruff G: Long-term results of closed nasolacrimal intubation in adults. Eur J Ophthalmol; 2007 Jul-Aug;17:490-493

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : . PURPOSE: Dacryocystorhinostomy (DCR) is the standard surgical treatment for adult nasolacrimal duct obstruction.

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  • (PMID = 28221539.001).
  • [ISSN] 1724-6016
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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81. Barbera LC, Krzyzanowska M, Elit L, Saskin R, Bierman A: Differences in uptake of postoperative adjuvant chemotherapy for lung cancer: Results from the Project for an Ontario Women's Health Evidence-Based Report Card (POWER) study. J Clin Oncol; 2009 May 20;27(15_suppl):6556

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All adult patients who underwent resection of NSCLC between April 2003 and May 2004 were included in the cohort.

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  • (PMID = 27963771.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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82. Moore A: Home sweet home. Nurs Stand; 2007 Jun 6-12;21(39):22
International Agency for Research on Cancer - Screening Group. diagnostics - Planning and Implementing Cervical Cancer Prevention and Control Programs: A Manual for Managers .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • But in one trust staff have been trained to approach the subject routinely with all adult patients--and services are on hand to help.

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  • (PMID = 17569372.001).
  • [ISSN] 0029-6570
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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83. Powell SF, Dudek AZ: Response to high-dose interleukin-2 (HD IL-2) therapy in patients with brain metastases from metastatic melanoma. J Clin Oncol; 2009 May 20;27(15_suppl):e20007

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A retrospective analysis was performed all adult patients with Stage IV melanoma treated with HD IL-2 from January 2000 to October 2008 at our institution.

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  • (PMID = 27962593.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Erba HP, Kantarjian HM, Claxton DF, Arellano M, Lyons RM, Kovacsovics TJ, Gabrilove J, Eckert S, Faderl S: Updated remission duration and survival results of single-agent clofarabine in previously untreated older adult patients with acute myelogenous leukemia (AML) unlikely to benefit from standard induction chemotherapy due to unfavorable baseline risk factor(s). J Clin Oncol; 2009 May 20;27(15_suppl):7062

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Updated remission duration and survival results of single-agent clofarabine in previously untreated older adult patients with acute myelogenous leukemia (AML) unlikely to benefit from standard induction chemotherapy due to unfavorable baseline risk factor(s).
  • CONCLUSIONS: These data expand on the previously reported efficacy and safety data of single agent CLO in adult AML.
  • These results suggest that single agent CLO is an effective and tolerable treatment option for older adult patients with untreated AML and 1 or more unfavorable baseline prognostic factor(s).

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  • (PMID = 27961436.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Olsen A: Military veterans and Social Security. Soc Secur Bull; 2005-2006;66(2):1-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There are 9.4 million military veterans receiving Social Security benefits, which means that almost one out of every four adult Social Security beneficiaries has served in the United States military.
  • In addition, veterans and their families make up almost 40 percent of the adult Social Security beneficiary population.
  • Veterans are overwhelmingly male compared with all adult Social Security beneficiaries who are more evenly split between males and females.
  • Military veterans receiving Social Security are more likely to be married and to have finished high school compared with all adult Social Security beneficiaries, and they are less likely to be poor or near poor than the overall beneficiary population.
  • Fourteen percent of veterans receiving Social Security benefits have income below 150 percent of poverty, while 25 percent of all adult Social Security beneficiaries are below this level.

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  • (PMID = 16878424.001).
  • [ISSN] 0037-7910
  • [Journal-full-title] Social security bulletin
  • [ISO-abbreviation] Soc Secur Bull
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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86. Mathieu D: [The bHLH TAL1 protein: a key molecule in the hematopoietic and endothelial systems]. J Soc Biol; 2009;203(2):143-53

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The formation of blood cells and vascular networks occurs simultaneously during development, and both lineages remain in close association in all adult tissues.
  • The functional setting of both systems within the embryo and their renewal during adult life are highly complex processes, and require the involvement of numerous molecular actors, the activities of which are often overlapping.
  • [MeSH-minor] Adaptor Proteins, Signal Transducing. Adult. Amino Acid Sequence. Animals. Antigens, CD / physiology. Cadherins / physiology. DNA-Binding Proteins / deficiency. DNA-Binding Proteins / genetics. DNA-Binding Proteins / physiology. Humans. LIM Domain Proteins. Metalloproteins / deficiency. Metalloproteins / genetics. Metalloproteins / physiology. Mice. Mice, Knockout. Models, Molecular. Molecular Sequence Data. Multiprotein Complexes. Protein Conformation. Sequence Alignment. Transcription, Genetic

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  • (PMID = 19527627.001).
  • [ISSN] 1295-0661
  • [Journal-full-title] Journal de la Société de biologie
  • [ISO-abbreviation] J. Soc. Biol.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Antigens, CD; 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / Cadherins; 0 / DNA-Binding Proteins; 0 / LIM Domain Proteins; 0 / LMO2 protein, human; 0 / Lmo2 protein, mouse; 0 / Metalloproteins; 0 / Multiprotein Complexes; 0 / Proto-Oncogene Proteins; 0 / Tal1 protein, mouse; 0 / cadherin 5; 135471-20-4 / TAL1 protein, human
  • [Number-of-references] 67
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87. Giantonio BJ, Forastiere AA, Comis RL, Eastern Cooperative Oncology Group: The role of the Eastern Cooperative Oncology Group in establishing standards of cancer care: over 50 years of progress through clinical research. Semin Oncol; 2008 Oct;35(5):494-506

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Since its start as the Eastern Cooperative Cancer Chemotherapy Group in 1955, the Eastern Cooperative Oncology Group (ECOG) has been at the vanguard of adult cancer clinical research in the United States, and for more than 50 years its research findings have influenced cancer care worldwide.
  • While the cancer clinical research milieu has changed considerably since its inception, the ECOG, through sound leadership and a committed membership, has maintained its pioneering roles in scientific discovery and defining standards of cancer care for all adult cancers.

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  • (PMID = 18929148.001).
  • [ISSN] 0093-7754
  • [Journal-full-title] Seminars in oncology
  • [ISO-abbreviation] Semin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 74
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88. Sharfman A, Staples V, Hughes H: Feasibility research on the potential use of Migrant Workers Scan data to improve migration and population statistics. Popul Trends; 2010;(140):36-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The MWS contains information on all adult overseas nationals who have registered for, and been allocated, a National Insurance Number (NINo).
  • [MeSH-minor] Adolescent. Adult. Aged. Emigrants and Immigrants / statistics & numerical data. Emigration and Immigration / statistics & numerical data. England. Feasibility Studies. Female. Humans. Male. Middle Aged. Population Dynamics. Wales

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  • (PMID = 20616800.001).
  • [ISSN] 0307-4463
  • [Journal-full-title] Population trends
  • [ISO-abbreviation] Popul Trends
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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89. Daley K, Huff S: Incidence of arrhythmias in ASA I patients in the phase I PACU. J Perianesth Nurs; 2010 Oct;25(5):281-5
MedlinePlus Health Information. consumer health - Arrhythmia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac monitoring is routinely performed on all adult patients in the immediate postoperative period in the Phase I PACU, regardless of the surgery/procedure or type of anesthesia given.

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  • [Copyright] Copyright © 2010 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20875881.001).
  • [ISSN] 1532-8473
  • [Journal-full-title] Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
  • [ISO-abbreviation] J. Perianesth. Nurs.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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90. Gyorki DE, Lindeman GJ: Macrophages, more than just scavengers: their role in breast development and cancer. ANZ J Surg; 2008 Jun;78(6):432-6
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Macrophages, derived from circulating monocytes, are located within virtually all adult tissues.

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  • (PMID = 18522560.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
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91. McKinnell IW, Parise G, Rudnicki MA: Muscle stem cells and regenerative myogenesis. Curr Top Dev Biol; 2005;71:113-30
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The source of this regenerative capacity has been attributed to "adult stem cells" that represent poorly understood multipotent cell lineages, believed to reside in all adult tissue populations.

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  • (PMID = 16344104.001).
  • [ISSN] 0070-2153
  • [Journal-full-title] Current topics in developmental biology
  • [ISO-abbreviation] Curr. Top. Dev. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 52
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92. Mangurian C, Miller GA, Jackson CT, Li H, Essock SM, Sederer LI: State mental health policy: Physical health screening in state mental health clinics: the New York health indicators initiative. Psychiatr Serv; 2010 Apr;61(4):346-8
International Agency for Research on Cancer - Screening Group. diagnostics - Planning and Implementing Cervical Cancer Prevention and Control Programs: A Manual for Managers .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The New York State Office of Mental Health recently mandated that all adult outpatient clinics regularly monitor three health indicators--body mass index, blood pressure, and smoking status.
  • [MeSH-minor] Adult. Health Plan Implementation / legislation & jurisprudence. Health Plan Implementation / organization & administration. Health Promotion / legislation & jurisprudence. Health Promotion / organization & administration. Humans. Inservice Training. Medical Records Systems, Computerized / legislation & jurisprudence. Medical Records Systems, Computerized / organization & administration. New York

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  • [CommentIn] Psychiatr Serv. 2011 Oct;62(10):1235; author reply 1235-6 [21969659.001]
  • (PMID = 20360272.001).
  • [ISSN] 1557-9700
  • [Journal-full-title] Psychiatric services (Washington, D.C.)
  • [ISO-abbreviation] Psychiatr Serv
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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93. Chugh R: Experimental therapies and clinical trials in bone sarcoma. J Natl Compr Canc Netw; 2010 Jun;8(6):715-25
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Because they constitute only 0.2% of all adult malignancies and 6% of pediatric malignancies, resources for studying this disease are often limited.

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  • (PMID = 20581301.001).
  • [ISSN] 1540-1405
  • [Journal-full-title] Journal of the National Comprehensive Cancer Network : JNCCN
  • [ISO-abbreviation] J Natl Compr Canc Netw
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor
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94. Bhatia S, Ng S, Hodder SC: Metastatic cutaneous head and neck renal cell carcinoma with no known primary: case report. Br J Oral Maxillofac Surg; 2010 Apr;48(3):214-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Renal cell carcinoma represents 2-3% of all adult malignancies, and metastasis to the head and neck is a presenting complaint in 8% of these patients.

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  • [Copyright] 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20036041.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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95. Downes MR, Thorne J, Tengku Khalid TN, Hassan HA, Leader M: Profile of sudden death in an adult population (1999-2008). Ir Med J; 2010 Jun;103(6):183-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Profile of sudden death in an adult population (1999-2008).
  • We retrospectively reviewed all adult post mortems performed at Beaumont Hospital over a decade (1999-2008).
  • This is the first Irish study to retrospectively review all adult sudden deaths within a defined catchment area and analyse them as outlined above.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Autopsy. Catchment Area (Health). Cause of Death. Female. Humans. Ireland / epidemiology. Male. Middle Aged. Retrospective Studies

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  • (PMID = 20669604.001).
  • [ISSN] 0332-3102
  • [Journal-full-title] Irish medical journal
  • [ISO-abbreviation] Ir Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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96. Newton SE: Alcohol relapse and its relationship to the lived experience of adult liver transplant recipients. Gastroenterol Nurs; 2007 Jan-Feb;30(1):37-42
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Alcohol relapse and its relationship to the lived experience of adult liver transplant recipients.
  • Abstinence from alcohol after liver transplantation is an important outcome for all adult liver transplant recipients to attain.
  • As a result, the contributions of nursing to abstinence counseling for adult liver transplant recipients are unknown.
  • For this study, a mixed method approach was used that combined the qualitative research method known as phenomenology with statistical findings to illuminate the lived experience of adult liver transplant recipients and to discover whether a relationship exists between the recipients' lived experiences and alcohol relapse after transplantation.
  • Nursing implications related to abstinence counseling for all adult liver transplant recipients are addressed.
  • [MeSH-minor] Adult. Comorbidity. Counseling. Employment / psychology. Female. Happiness. Humans. Liver Diseases, Alcoholic / etiology. Liver Diseases, Alcoholic / surgery. Male. Nurse's Role. Nursing Assessment. Nursing Methodology Research. Patient Education as Topic. Qualitative Research. Recurrence. Risk Assessment. Risk Factors. Surveys and Questionnaires


97. Jacobson JO, Brozovic S, Stahl JE, Papi M, Stankiewicz R: Risk factors for severe cancer chemotherapy toxicity in the outpatient setting: Results of a nested case control study using a novel patient cohort. J Clin Oncol; 2009 May 20;27(15_suppl):6545

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 6545 Background: Risk factors for severe cancer chemotherapy-related toxicity (resulting in hospitalization and/or death) in the adult outpatient setting are largely unknown.

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  • (PMID = 27964061.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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98. Martin I, Montheil V, Ropert S, Alexandre J, Goldwasser F, Durand JP: Incidence of chemotherapy-induced nausea and vomiting in 2008. J Clin Oncol; 2009 May 20;27(15_suppl):e20660

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e20660 Background: The authors determined the incidence of acute and delayed chemotherapy-induced nausea and vomiting (CINV) among new patients (pts) receiving chemotherapy with modern antiemetic prophylaxis in 2008.
  • METHODS: A prospective observational study of adult cancer pts receiving, for the first time, moderately or highly emetogenic chemotherapy (MEC or HEC) was performed.
  • Study participants were called on day 2 and day 8, after first and second cycle, to evaluate acute and delayed emesis according a 10-item questionnaire.
  • At cycle 1, on 124 assessable pts for acute emesis: 68 pts received MEC and 18, HEC.
  • 5.6% developed acute vomiting (5.9% for MEC and 5.6% for HEC) and 33.1%, acute nausea (39.7% for MEC and 44.4% for HEC).
  • At cycle 2, on 121 assessable pts for acute emesis: 62 pts received MEC and 18, HEC.
  • 8.3% developed acute vomiting (6.5% for MEC and 16.3% for HEC) and 31.4%, acute nausea (35.5% for MEC and 44.4% for HEC).

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  • (PMID = 27961722.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Navari RM, Gray SE: Treatment of chemotherapy-induced breakthrough nauea and vomiting. J Clin Oncol; 2009 May 20;27(15_suppl):e20536

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Adult patients, receiving moderately emetogenic chemotherapy and CINV prophylaxis with a 5-hydroxytryptamine-3 receptor antagonist and Dex pre-chemotherapy and Dex post-chemotherapy according to ASCO guidelines, who experienced BNV during the five days post-chemotherapy were randomized to receive Pro, 10 mg IV, and 10 mg, po, bid for three days; Meto, 20 mg IV, and 10 mg, po, bid for 3 days; or Dex, 20 mg IV and Olan, 5 mg, po, bid for three days.

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  • (PMID = 27960973.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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100. McManus BL, Fuller BW, Boetel MA, French BW, Ellsbury MM, Head GP: Abundance of Coleomegilla maculata (Coleoptera: Coccinellidae) in corn rootworm-resistant Cry3Bb1 maize. J Econ Entomol; 2005 Dec;98(6):1992-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It comprised 73.5 and 69.9% of all adult Coccinellidae caught in 2001 and 2002, respectively.
  • Whole-plant sampling confirmed C. maculata predominance with the species representing 89.2 and 91.4% of all adult lady beetles observed in 2001 and 2002, respectively.

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  • (PMID = 16539124.001).
  • [ISSN] 0022-0493
  • [Journal-full-title] Journal of economic entomology
  • [ISO-abbreviation] J. Econ. Entomol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cry3Bbl endotoxin, Bacillus thuringiensis; 0 / Endotoxins
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