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Items 1 to 39 of about 39
1. Chittithaworn S, Hanprasertpong J, Tungsinmunkong K, Geater A: Association between prognostic factors and disease-free survival of cervical cancer stage IB1 patients undergoing radical hysterectomy. Asian Pac J Cancer Prev; 2007 Oct-Dec;8(4):530-4
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association between prognostic factors and disease-free survival of cervical cancer stage IB1 patients undergoing radical hysterectomy.
  • This study was designed to identify prognostic factors of patients with cervical cancer stage IB1 undergoing radical hysterectomy.
  • The medical records and specimens of two hundred and five patients with cervical cancer stage IB1 undergoing radical hysterectomy at Songklanagarind Hospital from July 1995 to June 2005 were reviewed.
  • In conclusion, degree of stromal invasion was the main independent predictor of prognosis in surgical cases of cervical cancer stage IB1.
  • [MeSH-major] Hysterectomy. Uterine Cervical Neoplasms / pathology. Uterine Cervical Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adult. Carcinoma, Adenosquamous / pathology. Carcinoma, Adenosquamous / surgery. Carcinoma, Small Cell / pathology. Carcinoma, Small Cell / surgery. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Disease-Free Survival. Female. Humans. Lymph Node Excision. Lymph Nodes / pathology. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Survival Rate. Treatment Outcome

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  • (PMID = 18260723.001).
  • [ISSN] 2476-762X
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Thailand
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2. Einstein MH, Park KJ, Sonoda Y, Carter J, Chi DS, Barakat RR, Abu-Rustum NR: Radical vaginal versus abdominal trachelectomy for stage IB1 cervical cancer: a comparison of surgical and pathologic outcomes. Gynecol Oncol; 2009 Jan;112(1):73-7
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radical vaginal versus abdominal trachelectomy for stage IB1 cervical cancer: a comparison of surgical and pathologic outcomes.
  • OBJECTIVES: To compare the surgical and pathologic outcomes utilizing two surgical approaches for fertility-sparing radical trachelectomy in patients with stage IB1 cervical cancer.
  • RESULTS: Between 12/2001 and 7/2007, 43 adult patients with FIGO stage IB1 cervical cancer underwent surgery with the intent to perform a fertility-sparing radical trachelectomy.
  • [MeSH-major] Gynecologic Surgical Procedures / methods. Uterine Cervical Neoplasms / surgery

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  • (PMID = 18973933.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA008748
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS810676; NLM/ PMC4994890
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3. Naik R, Cross P, Nayar A, Mayadevi S, Lopes A, Godfrey K, Hatem H: Conservative surgical management of small-volume stage IB1 cervical cancer. BJOG; 2007 Aug;114(8):958-63
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conservative surgical management of small-volume stage IB1 cervical cancer.
  • OBJECTIVE: To determine outcomes of women with small-volume stage IB1 disease managed by conservative surgical treatment.
  • POPULATION: Women with stage IB1 cervical cancer who were managed by conservative surgery over a 6-year period between 1 January 2000 and 31 December 2005.
  • RESULTS: A total of 17 women with conservatively managed stage IB1 cervical cancer were identified.
  • CONCLUSIONS: The conservative surgical management of small-volume stage IB1 cases in this series showed an excellent outcome with no cases showing pelvic lymph node involvement and no cases developing recurrent disease.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma, Squamous Cell / surgery. Uterine Cervical Neoplasms / surgery

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  • (PMID = 17578471.001).
  • [ISSN] 1471-0528
  • [Journal-full-title] BJOG : an international journal of obstetrics and gynaecology
  • [ISO-abbreviation] BJOG
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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4. Chandacham A, Charoenkwan K, Siriaunkgul S, Srisomboon J, Suprasert P, Phongnarisorn C, Cheewakraingkrai C, Siriaree S, Tantipalakorn C, Kietpeerakool C: Extent of lymphovascular space invasion and risk of pelvic lymph node metastases in stage IB1 cervical cancer. J Med Assoc Thai; 2005 Oct;88 Suppl 2:S31-6
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extent of lymphovascular space invasion and risk of pelvic lymph node metastases in stage IB1 cervical cancer.
  • OBJECTIVE: To evaluate whether the extent of lymphovascular space invasion (LVSI) is a risk factor for pelvic lymph node metastases in stage IBI cervical cancer.
  • MATERIAL AND METHOD: The clinicopathological data of 397 patients with stage IB1 cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy (RHPL) at Chiang Mai University Hospital between January 1998 and December 2002 were analyzed.
  • The histology, tumor grade, depth of stromal invasion, uterine corpus involvement, parametrial invasion and LVSI were analyzed for their association with pelvic node metastases.
  • The extent of LVSI was classified as negative, minimal (< 10 LVSI/cervical specimen), and extensive (> or = 10 LVSI/cervical specimen).
  • CONCLUSION: The presence of LVSI especially extensive involvement was significantly associated with the risk of pelvic node metastases in stage IB1 cervical cancer.
  • [MeSH-major] Lymph Nodes / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 17722314.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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5. Ferrandina G, Salutari V, Testa A, Zannoni GF, Petrillo M, Scambia G: Recurrence in skeletal muscle from squamous cell carcinoma of the uterine cervix: a case report and review of the literature. BMC Cancer; 2006;6:169
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrence in skeletal muscle from squamous cell carcinoma of the uterine cervix: a case report and review of the literature.
  • Only two cases of late skeletal muscle recurrence from cervical cancer have been documented until now.
  • CASE PRESENTATION: A 38-year old patient, submitted to radical hysterectomy and pelvic lymphadenectomy for a squamous FIGO stage IB1 cervical carcinoma, presented after 76 months with a palpable, and painless swelling on the left hemithorax.
  • Pathology revealed the presence of metastasis of squamous cell carcinoma of similar morphology as the primary.
  • CONCLUSION: A case of skeletal muscle recurrence from cervical cancer after a very long interval from primary diagnosis is reported.
  • Muscular pain or weakness, or just a palpable mass in a patient with a history of cancer has always to raise the suspicion of muscle metastasis.
  • [MeSH-major] Carcinoma, Squamous Cell / secondary. Muscle Neoplasms / secondary. Muscle, Skeletal. Thoracic Wall. Uterine Cervical Neoplasms

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  • (PMID = 16800899.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 14
  • [Other-IDs] NLM/ PMC1523362
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6. Abu-Rustum NR, Tal MN, DeLair D, Shih K, Sonoda Y: Radical abdominal trachelectomy for stage IB1 cervical cancer at 15-week gestation. Gynecol Oncol; 2010 Jan;116(1):151-2
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radical abdominal trachelectomy for stage IB1 cervical cancer at 15-week gestation.
  • OBJECTIVE: The management of stage IB1 cervical cancer at 15 weeks pregnancy remains a significant challenge from both the oncologic and obstetrical standpoints.
  • Abdominal trachelectomy has been recently described as a potential option in patients who have a very strong desire to attempt preservation of pregnancy and treat the cancer without delay.
  • CASE: A 37-year-old female, presented for prenatal care in the first trimester and was diagnosed with a FIGO stage IB1 poorly differentiated lymphoepithelioma like cervical cancer on conization.
  • CONCLUSION: Recent advances in fertility-sparing surgery for stage IB1 cervical cancer lead to the successful utilization of radical abdominal trachelectomy during the early second trimester of pregnancy.
  • Radical trachelectomy may broaden the treatment options for pregnant women with stage IB1 cervical cancer who have a strong desire to avoid definitive pregnancy termination and commence treatment without delay.
  • [MeSH-major] Pregnancy Complications, Neoplastic / surgery. Uterine Cervical Neoplasms / surgery


7. Abu-Rustum NR, Neubauer N, Sonoda Y, Park KJ, Gemignani M, Alektiar KM, Tew W, Leitao MM, Chi DS, Barakat RR: Surgical and pathologic outcomes of fertility-sparing radical abdominal trachelectomy for FIGO stage IB1 cervical cancer. Gynecol Oncol; 2008 Nov;111(2):261-4
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical and pathologic outcomes of fertility-sparing radical abdominal trachelectomy for FIGO stage IB1 cervical cancer.
  • METHODS: A prospectively maintained database of all patients with FIGO stage IB1 cervical cancer admitted to the operating room for planned fertility-sparing radical abdominal trachelectomy was analyzed.
  • Sentinel node mapping was performed via cervical injection of Technetium and blue dye.
  • RESULTS: Between 6/2005 and 5/2008, 22 consecutive patients with FIGO stage IB1 cervical cancer underwent laparotomy for planned fertility-sparing radical abdominal trachelectomy.
  • Histology included 13 (59%) with adenocarcinoma and 9 (41%) with squamous carcinoma.
  • Eighteen of 19 (95%) patients who completed trachelectomy had a cerclage placed, and 9/22 (41%) patients had no residual cervical carcinoma on final pathology.
  • CONCLUSIONS: Cervical adenocarcinoma and lymph-vascular invasion are common features of patients selected for radical abdominal trachelectomy.
  • [MeSH-major] Fertility. Uterine Cervical Neoplasms / pathology. Uterine Cervical Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adult. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Female. Gynecologic Surgical Procedures / methods. Humans. Lymphatic Metastasis. Neoplasm Staging. Treatment Outcome. Young Adult

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  • (PMID = 18708244.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA008748
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS810675; NLM/ PMC4994885
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8. Favero G, Lanowska M, Schneider A, Marnitz S, Köhler C: Laparoscopic pelvic lymphadenectomy in a patient with cervical cancer stage Ib1 complicated by a twin pregnancy. J Minim Invasive Gynecol; 2010 Jan-Feb;17(1):118-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic pelvic lymphadenectomy in a patient with cervical cancer stage Ib1 complicated by a twin pregnancy.
  • Cervical cancer is the most frequently observed malignancy during pregnancy.
  • To our knowledge, this is the first report of a twin pregnancy complicated by cancer of the uterine cervix that was successfully treated with laparoscopic pelvic lymphadenectomy and subsequently with neoadjuvant chemotherapy.
  • Cervical adenocarcinoma, grade 2, stage 1b1 with lymphovascular space invasion was diagnosed.
  • [MeSH-major] Adenocarcinoma / surgery. Lymph Node Excision. Pregnancy Complications, Neoplastic / surgery. Pregnancy, Multiple. Uterine Cervical Neoplasms / surgery


9. Maneo A, Chiari S, Bonazzi C, Mangioni C: Neoadjuvant chemotherapy and conservative surgery for stage IB1 cervical cancer. Gynecol Oncol; 2008 Dec;111(3):438-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neoadjuvant chemotherapy and conservative surgery for stage IB1 cervical cancer.
  • OBJECTIVES: To assess the effectiveness of chemo-surgical conservative therapy for stage IB1 cervical tumors in patients desiring to preserve fertility.
  • METHODS: From 1995 to April 2007 51 nulliparous patients with tumor <or=3 cm, aged <or=40 years with no uterine and lymphnode neoplastic involvement were evaluated.
  • When intraoperative frozen section revealed massive neoplastic cervical persistence a radical total hysterectomy was performed.
  • CONCLUSIONS: The high rate of pathological response confirms the effectiveness of the preoperative treatment for reducing the tumor volume allowing the removal only of a cervical cone instead of the entire cervix with cardinal ligaments as needed by radical trachelectomy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Uterine Cervical Neoplasms / drug therapy. Uterine Cervical Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adult. Carcinoma, Squamous Cell / drug therapy. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Chemotherapy, Adjuvant. Cisplatin / administration & dosage. Cisplatin / adverse effects. Conization. Epirubicin / administration & dosage. Epirubicin / adverse effects. Female. Humans. Hysterectomy. Ifosfamide / administration & dosage. Ifosfamide / adverse effects. Lymph Node Excision. Neoadjuvant Therapy. Neoplasm Staging. Paclitaxel / administration & dosage. Paclitaxel / adverse effects. Young Adult


10. Gurney EP, Blank SV: Postpartum radical trachelectomy for IB1 squamous cell carcinoma of the cervix diagnosed in pregnancy. Am J Obstet Gynecol; 2009 Oct;201(4):e8-e10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Postpartum radical trachelectomy for IB1 squamous cell carcinoma of the cervix diagnosed in pregnancy.
  • Standard management of stage IB1 cervical cancer in pregnancy is radical hysterectomy with fetus in situ if diagnosis precedes viability, or cesarean radical hysterectomy.
  • Postpartum abdominal radical trachelectomy was performed as an alternative, fertility-preserving surgery in a 30-year-old nulliparous woman diagnosed with stage IB1 cervical at 21 weeks' gestation.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Cervix Uteri / surgery. Pregnancy Complications, Neoplastic / surgery. Uterine Cervical Neoplasms / surgery


11. Pellegrino A, Vizza E, Fruscio R, Villa A, Corrado G, Villa M, Dell'Anna T, Vitobello D: Total laparoscopic radical hysterectomy and pelvic lymphadenectomy in patients with Ib1 stage cervical cancer: analysis of surgical and oncological outcome. Eur J Surg Oncol; 2009 Jan;35(1):98-103
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Total laparoscopic radical hysterectomy and pelvic lymphadenectomy in patients with Ib1 stage cervical cancer: analysis of surgical and oncological outcome.
  • AIM: To evaluate safety, feasibility and oncological outcome of total laparoscopic radical hysterectomy (TLRH) in patients with early invasive cervical cancer.
  • METHODS: Data of patients with Ib1 cervical cancer who underwent TLRH were prospectively collected.
  • [MeSH-major] Hysterectomy / methods. Laparoscopy / methods. Lymph Node Excision / methods. Uterine Cervical Neoplasms / surgery

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  • (PMID = 18760562.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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12. Palaia I, Perniola G, Arrivi C, Sansone M, Pastore M, Calcagno M, Panici PB: Persistent posttrachelectomy cervical stenosis treated with Petit-Le Four pessary in early cervical cancer patients: a report of two cases. Fertil Steril; 2007 Dec;88(6):1677.e5-7
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Persistent posttrachelectomy cervical stenosis treated with Petit-Le Four pessary in early cervical cancer patients: a report of two cases.
  • OBJECTIVE: To report on posttrachelectomy refractory cervical stenosis in two women with early cervical cancer that was resolved by using a Petit-Le Four tube, an older type of cervical pessary.
  • PATIENT(S): Two young women with FIGO stage IB1 cervical cancer and posttrachelectomy cervical stenosis.
  • INTERVENTION(S): Cervical dilatations and Petit-Le Four cervical pessary insertion.
  • RESULT(S): The Petit-Le Four cervical pessary is a good therapeutic option for the treatment of cervical stenosis after trachelectomy performed for early cervical cancer.
  • CONCLUSION(S): Persistent hematometra from cervical stenosis could compromise both fertility and quality of life, and often requires dilatation of the cervical ostium, which must be performed several times in the same patient to obtain optimal results.
  • Cervical dilators left in place could help physicians in the treatment of recurrent cervical stenosis after trachelectomy.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Intrauterine Devices. Postoperative Complications / therapy. Uterine Cervical Diseases / therapy. Uterine Cervical Neoplasms / surgery


13. De La Mota J, Thomas B, Fengwei W, Micaily B, Yajue H, Hernandez E: Surgical and immunohistochemical (IC) risk factors for metastatic disease in stage IB1 cervical cancer (CC). J Clin Oncol; 2009 May 20;27(15_suppl):e16578

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical and immunohistochemical (IC) risk factors for metastatic disease in stage IB1 cervical cancer (CC).
  • : e16578 Background: Stage IB1 CC is treated with radical abdominal hysterectomy (RH) and pelvic lymph node dissection (LND) because of presumed risk of parametrial and nodal involvement.
  • METHODS: Retrospective chart review of all stage IB1 CC patients who underwent RH and LND from 1996-2008.
  • In addition six patients with LVI and deep cervical stromal invasion received adjuvant radiation therapy.
  • CONCLUSIONS: The rate of LN metastasis in patients with stage IB1 CC is significant (14 %), as is the rate of parametrial involvement (6%).

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  • (PMID = 27961498.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Elzevier HW, Gaarenstroom KN, Lycklama á Nijeholt AA: Sexual function after partial cystectomy and urothelial stripping in a 32-year-old woman with radiation cystitis. Int Urogynecol J Pelvic Floor Dysfunct; 2005 Sep-Oct;16(5):412-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • After radiotherapy for stage IB1 cervical cancer, cystectomy was indicated because of severe radiation cystitis.
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Humans. Uterine Cervical Neoplasms / radiotherapy

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  • (PMID = 15647882.001).
  • [Journal-full-title] International urogynecology journal and pelvic floor dysfunction
  • [ISO-abbreviation] Int Urogynecol J Pelvic Floor Dysfunct
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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15. Kobayashi E, Iwamiya T, Masaki H, Yamagata A, Isobe M, Miyake T, Shiki Y, Nakashima R, Yamasaki M: Postoperative abdominal aspergilloma mimicking cervical cancer recurrence and diagnostic imaging, including F-fluorodeoxyglucose positron emission tomography, with false-positive findings. J Obstet Gynaecol Res; 2009 Aug;35(4):808-11
International Agency for Research on Cancer - Screening Group. diagnostics - A practical manual on visual screening for cervical neoplasia .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Postoperative abdominal aspergilloma mimicking cervical cancer recurrence and diagnostic imaging, including F-fluorodeoxyglucose positron emission tomography, with false-positive findings.
  • The patient had undergone radical hysterectomy for stage Ib1 cervical cancer.
  • Six months after the surgery, she was found to have an elevated concentration of the serum squamous cell carcinoma antigen.
  • Therefore, we could not rule out the possibility of the peritoneal dissemination of cervical cancer, and we resected the mass.
  • [MeSH-major] Abdomen / microbiology. Aspergillosis / diagnosis. Fluorodeoxyglucose F18. Neoplasm Recurrence, Local / diagnosis. Positron-Emission Tomography. Postoperative Complications / diagnosis. Radiopharmaceuticals. Uterine Cervical Neoplasms / surgery

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  • (PMID = 19751349.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Radiopharmaceuticals; 0 / Serpins; 0 / squamous cell carcinoma-related antigen; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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16. Bentivegna E, Uzan C, Gouy S, Leboulleux S, Duvillard P, Lumbroso J, Haie-Meder C, Schlumberger M, Morice P: Correlation between [18f]fluorodeoxyglucose positron-emission tomography scan and histology of pelvic nodes in early-stage cervical cancer. Anticancer Res; 2010 Mar;30(3):1029-32
International Agency for Research on Cancer - Screening Group. diagnostics - A practical manual on visual screening for cervical neoplasia .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correlation between [18f]fluorodeoxyglucose positron-emission tomography scan and histology of pelvic nodes in early-stage cervical cancer.
  • BACKGROUND: The histological results of pelvic lymphadenectomy were studied in patients treated for early-stage cervical cancer (<4 cm) who had no nodal uptake on [(18)F]fluorodeoxyglucose positron-emission tomography combined with integrated computed tomography (FDG-PET/CT).
  • PATIENTS AND METHODS: Patients treated between 2005 and 2008 for stage IB1 cervical cancer cancer <4 cm who underwent a FDG-PET/CT followed by surgical evaluation of pelvic nodes were reviewed.
  • CONCLUSION: The accuracy of PET-CT imaging in predicting the pelvic nodal status is very low in patients with early-stage cervical cancer and is not able to replace lymphadenectomy.
  • [MeSH-major] Fluorodeoxyglucose F18. Lymph Nodes / radionuclide imaging. Radiopharmaceuticals. Uterine Cervical Neoplasms / radionuclide imaging


17. Kukura V, Ciglar S, Markulin-Grgić L, Santek F: Adjuvant therapy after radical surgery of cervical cancer: Zagreb experience. Coll Antropol; 2007 Apr;31 Suppl 2:155-8
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adjuvant therapy after radical surgery of cervical cancer: Zagreb experience.
  • The results of the analysis of the treatment of 72 patients with carcinoma of the uterine cervix are presented.
  • Seventy-two patients with Stage IB1 carcinoma of the cervix underwent a radical hysterectomy and pelvic lymphadenectomy.
  • The high-risk group included women with pelvic node metastases, clinical tumour size greater than 3.0 cm, depth of stromal invasion greater than 1/3 of the cervical wall, Grade 3 tumours and the presence of lympho-vascular space involvement.
  • Five-year overall survival, locoregional and distant metastases were similar in the low-risk and high-risk groups of patients, which emphasizes the value of whole pelvic radiation in patients with one or more unfavourable prognostic factors after radical surgery in Stage IB1 cervical cancer
  • [MeSH-major] Uterine Cervical Neoplasms / surgery

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  • (PMID = 17598519.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Croatia
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18. Kim MK, Kim JW, Kim MA, Kim HS, Chung HH, Park NH, Park IA, Song YS, Kang SB: Feasibility of less radical surgery for superficially invasive carcinoma of the cervix. Gynecol Oncol; 2010 Nov;119(2):187-91
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Feasibility of less radical surgery for superficially invasive carcinoma of the cervix.
  • OBJECTIVE: To determine the incidence of parametrial involvement in patients with superficially invasive cervical cancer and to assess the feasibility of less radical surgery in this subset of patients.
  • PATIENTS AND METHODS: A retrospective analysis was performed in 375 patients with stage IB1 cervical cancer who underwent radical surgery at Seoul National University Hospital from 2000 to 2008.
  • CONCLUSION: We have demonstrated that stage IB1 patients with depth of invasion≤5 mm are at very low risk for parametrial involvement.
  • [MeSH-major] Uterine Cervical Neoplasms / pathology. Uterine Cervical Neoplasms / surgery

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20663542.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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19. Kim YT, Kim SW, Hyung WJ, Lee SJ, Nam EJ, Lee WJ: Robotic radical hysterectomy with pelvic lymphadenectomy for cervical carcinoma: a pilot study. Gynecol Oncol; 2008 Feb;108(2):312-6
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Robotic radical hysterectomy with pelvic lymphadenectomy for cervical carcinoma: a pilot study.
  • OBJECTIVES: The purpose of this study was to evaluate the feasibility and surgical outcome of robotic radical hysterectomy with pelvic lymphadenectomy for stage I cervical carcinoma using the da Vinci surgical system.
  • METHODS: A retrospective clinical review was performed of ten patients with FIGO stage IA2-IB1 cervical carcinoma who underwent a total robotic approach for definitive surgical treatment.
  • CONCLUSIONS: Robotic radical hysterectomy with pelvic lymphadenectomy for selected patients with stage IB1 cervical cancer is feasible, promising and related with a low morbidity in this pilot study.
  • [MeSH-major] Hysterectomy / methods. Lymph Node Excision / methods. Robotics / methods. Uterine Cervical Neoplasms / surgery

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  • (PMID = 18035405.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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20. Iida T, Yasuda M, Kajiwara H, Minematsu T, Osamura RY, Itoh J, Inomo A, Hirasawa T, Muramatsu T, Murakami M: Case of uterine cervical carcinosarcoma. J Obstet Gynaecol Res; 2005 Oct;31(5):404-8
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case of uterine cervical carcinosarcoma.
  • CS of the uterine cervix is much less common than its counterparts in the uterine corpus.
  • A 61-year-old, gravida 2, para 2 woman, who had undergone menopause 16 years prior to the presentation, was diagnosed with CS of the uterine cervix.
  • A semiradical hysterectomy was carried out on the diagnosis of stage Ib1 cervical cancer.
  • The tumor protruded from the cervix to the vagina and measured 4.5 x 3.0 cm.
  • Histologically, the tumor was characterized as a squamous cell carcinoma and mesenchymal malignancy, represented by osteosarcomatous components.
  • Uterine cervical CS is one of the aggressive malignancies, and squamous cell carcinomas are common epithelial counterparts of cervical CS as well as adenocarcinomas.
  • [MeSH-major] Carcinosarcoma / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 16176508.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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21. Canton-Romero JC, Anaya-Prado R, Rodriguez-Garcia HA, Mejia-Romo F, De-Los-Rios PE, Cortez-Martinez G, Delgado-Ramirez R, Quijano F: Laparoscopic radical hysterectomy with the use of a modified uterine manipulator for the management of stage IB1 cervix cancer. J Obstet Gynaecol; 2010 Jan;30(1):49-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic radical hysterectomy with the use of a modified uterine manipulator for the management of stage IB1 cervix cancer.
  • We prospectively collected data on all patients with stage IB1 cervical cancer, who underwent total laparoscopic radical hysterectomy with the use of a modified uterine manipulator.
  • Squamous carcinoma and adenocarcinoma were found in 88.88% and 11.11% of the cases, respectively.
  • The use of a uterine manipulator does not pose an increased surgical risk and allows for a simpler and more feasible procedure.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma, Squamous Cell / surgery. Hysterectomy, Vaginal / instrumentation. Laparoscopy / methods. Uterine Cervical Neoplasms / surgery

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  • (PMID = 20121505.001).
  • [ISSN] 1364-6893
  • [Journal-full-title] Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
  • [ISO-abbreviation] J Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] England
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22. dos Reis R, Frumovitz M, Milam MR, Capp E, Sun CC, Coleman RL, Ramirez PT: Adenosquamous carcinoma versus adenocarcinoma in early-stage cervical cancer patients undergoing radical hysterectomy: an outcomes analysis. Gynecol Oncol; 2007 Dec;107(3):458-63
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenosquamous carcinoma versus adenocarcinoma in early-stage cervical cancer patients undergoing radical hysterectomy: an outcomes analysis.
  • OBJECTIVE: To evaluate whether histology (adenocarcinoma versus adenosquamous carcinoma) is an independent prognostic indicator in patients with stage IB1 cervical cancer after radical hysterectomy.
  • METHODS: All patients with adenocarcinoma or adenosquamous carcinoma who underwent radical hysterectomy between October 1990 and December 2006 at The University of Texas M. D.
  • Anderson Cancer Center were evaluated.
  • Clinico-pathological data collected included age, disease stage, tumor grade, lymph node status, parametrial involvement, depth of invasion, evidence of lymph-vascular space invasion (LVSI), and adjuvant therapy.
  • RESULTS: We identified 126 patients with stage IB1 adenosquamous (n=29) or adenocarcinoma (n=97) cervical cancer.
  • The median age was 40.3 years for patients with adenocarcinoma and 35.2 years for patients with adenosquamous carcinoma (P=0.88).
  • There was no difference in recurrence rates between the two histologic groups, but the time to recurrence was shorter for patients with adenosquamous carcinoma (7.9 months versus 15 months; P=0.01).
  • CONCLUSION: We found no evidence that histologic subtype affects outcome; however, the median time to recurrence was shorter in patients with adenosquamous carcinoma.
  • Our study suggests that in patients with stage IB1 adenosquamous carcinoma or adenocarcinoma, the presence of high-risk features is more important than histologic subtype.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Carcinoma, Adenosquamous / pathology. Carcinoma, Adenosquamous / surgery. Uterine Cervical Neoplasms / pathology. Uterine Cervical Neoplasms / surgery

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  • (PMID = 17854872.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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23. Del Priore G, Ungar L, Smith JR: Complications after fertility-preserving radical trachelectomy. Fertil Steril; 2006 Jan;85(1):227
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: We report a case of cervical cancer treated by radical trachelectomy complicated by pelvic inflammatory disease, tubo-ovarian complex, and infertility.
  • PATIENT(S): A 35-year-old with stage IB1 cervical cancer underwent an uneventful radical vaginal trachelectomy.
  • Cervical chlamydia was positive, and sonography showed bilateral complex adnexal masses.
  • She remains cancer free.
  • MAIN OUTCOME MEASURE(S): Cancer disease status and fertility preservation.
  • RESULT(S): Three years later, the patient remains cancer free but has been unable to conceive or carry a pregnancy.
  • CONCLUSION(S): Fertility-preserving cancer treatments are relatively new.
  • Complications may be encountered that must be reported, collected, and analyzed to maximize cancer cure and fertility preservation.
  • [MeSH-major] Infertility, Female / etiology. Pelvic Inflammatory Disease / complications. Uterine Cervical Neoplasms / complications. Uterine Cervical Neoplasms / surgery

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  • (PMID = 16412761.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Sharma R, Bailey J, Anderson R, Murdoch J: Laparoscopically assisted radical vaginal hysterectomy (Coelio-Schauta): A comparison with open Wertheim/Meigs hysterectomy. Int J Gynecol Cancer; 2006 Sep-Oct;16(5):1927-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We retrospectively analyzed records of our first 35 consecutive patients undergoing laparoscopically assisted radical vaginal hysterectomy (LARVH) for early cervical cancer and 32 consecutive patients of open radical hysterectomy (ORH) performed between 1999 and 2005 in our institution.
  • The FIGO stage, excision margins, node count and node status, follow-up, and recurrence rates were also taken into account.
  • We excluded stage IA and stage II disease patients to reduce the impact of tumor size on the outcome of the surgery.
  • This left 27 patients with stage IIB disease who had LARVH and 28 patients with stage IB disease who had ORH.
  • The cohorts were similar in age, bodyweight, previous abdominal surgery, histologic subtype, FIGO stage, resection margins, node count and node status, length of follow-up, and recurrence.
  • Our data confirm that LARVH is a suitable alternative to ORH hysterectomy for small-volume stage IB1 cervical cancer with similar clinical efficacy and a superior postoperative recovery and postoperative morbidity profile.
  • [MeSH-major] Carcinoma / surgery. Hysterectomy, Vaginal / methods. Uterine Cervical Neoplasms / surgery

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  • (PMID = 17009993.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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25. Pellegrino A, Villa A, Fruscio R, Signorelli M, Meroni MG, Iedà N, Vitobello D: Total laparoscopic radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer. Surg Laparosc Endosc Percutan Tech; 2008 Oct;18(5):474-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Total laparoscopic radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer.
  • OBJECTIVES: The aim of the study was to evaluate the adequacy, morbidity, and survival outcome of laparoscopic type II radical hysterectomy and pelvic lymphadenectomy in patients with early invasive cervical cancer.
  • The majority of patients (86%) had FIGO stage Ib1 cervical cancer, and the predominant histotype was squamous (59%).
  • CONCLUSIONS: TLRH with pelvic lymphadenectomy is an adequate and feasible surgical option in treating early invasive cervical cancer; however a longer follow-up is required to evaluate the oncologic outcome of these patients.
  • [MeSH-major] Hysterectomy / methods. Laparoscopy / methods. Lymph Node Excision. Uterine Cervical Neoplasms / surgery

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  • (PMID = 18936669.001).
  • [ISSN] 1534-4908
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Diaz JP, Sonoda Y, Leitao MM, Zivanovic O, Brown CL, Chi DS, Barakat RR, Abu-Rustum NR: Oncologic outcome of fertility-sparing radical trachelectomy versus radical hysterectomy for stage IB1 cervical carcinoma. Gynecol Oncol; 2008 Nov;111(2):255-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oncologic outcome of fertility-sparing radical trachelectomy versus radical hysterectomy for stage IB1 cervical carcinoma.
  • OBJECTIVE: To compare the oncologic outcomes of women who underwent a fertility-sparing radical trachelectomy (RT) to those who underwent a radical hysterectomy (RH) for stage IB1 cervical carcinoma.
  • METHODS: We performed a case-control study of all patients with stage IB1 cervical carcinoma who underwent a vaginal or abdominal RT between 11/01 and 6/07.
  • The control group consisted of patients with stage IB1 disease who underwent an RH between 11/91 and 6/07 and who would be considered candidates for fertility-sparing surgery.
  • RESULTS: Forty stage IB1 patients underwent an RT and 110 patients underwent an RH.
  • On multivariate analysis in this group of stage IB1 lesions, tumor size <2 cm was not an independent predictor of outcome, but both LVSI and DSI retained independent predictive value (P=0.033 and 0.005, respectively).
  • CONCLUSION: For selected patients with stage IB1 cervical cancer, fertility-sparing radical trachelectomy appears to have a similar oncologic outcome to radical hysterectomy.
  • [MeSH-major] Fertility. Uterine Cervical Neoplasms / surgery


27. Kesic V: Management of cervical cancer. Eur J Surg Oncol; 2006 Oct;32(8):832-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of cervical cancer.
  • AIMS: The aim of the article was to review the current approach to management of cervical cancer.
  • METHODS: The relevant literature has served as a source for review of different options applied in the management of cervical cancer.
  • RESULTS: Treatment of invasive cervical cancer is affected by the stage of the disease, which is based on clinical evaluation.
  • Microinvasive carcinoma of the cervix has limited metastatic potential and therefore is most likely curable by non-radical treatment.
  • There is no standard management of stage Ib-IIa cervical carcinoma.
  • Most often, stage Ib1 cervical cancer is treated by radical hysterectomy with pelvic lymphadenectomy.
  • Radical vaginal trachelectomy with laparoscopic pelvic lymphadenectomy may be an option in small cervical cancer where preservation of fertility is desired.
  • There is lot of conflicting published work regarding the treatment of bulky stage Ib-IIa cervical cancer.
  • While some centers are performing primary surgery as for Ib1 disease followed by tailored postoperative radiation with or without chemotherapy, the others are in favor of primary chemo-radiation therapy.
  • Neoadjuvant chemotherapy followed by radical surgery has emerged as a possible alternative, which may improve a survival in patients with stage Ib2 disease.
  • CONCLUSIONS: Treatment decisions should be individualized and based on multiple factors including the stage of the disease, age, medical condition of the patient, tumor-related factors and treatment preferences, to yield the best cure with minimum complications.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Hysterectomy / methods. Uterine Cervical Neoplasms / therapy

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  • (PMID = 16698223.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 42
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28. Pareja F R, Ramirez PT, Borrero F M, Angel C G: Abdominal radical trachelectomy for invasive cervical cancer: a case series and literature review. Gynecol Oncol; 2008 Dec;111(3):555-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abdominal radical trachelectomy for invasive cervical cancer: a case series and literature review.
  • OBJECTIVE: The objective of this study was to review our experience with abdominal radical trachelectomy in patients with early-stage cervical cancer.
  • Data collected included age, stage, histopathologic subtype, tumor size, evidence of lymph-vascular space invasion, estimated blood loss, number of perioperative blood transfusions, number and disease status of lymph nodes removed, disease status of surgical specimen, length of hospital stay, intraoperative and postoperative complications, follow-up time, and fertility outcomes.
  • Three patients had stage IA2 and 12 had stage IB1 cervical cancer.
  • Eleven patients had squamous cell carcinoma and 4 had adenocarcinoma.
  • Thirteen patients were diagnosed by cervical conization and 2 by colposcopically directed biopsy.
  • CONCLUSION: Abdominal radical trachelectomy is feasible and can be performed safely in a developing country in well-selected patients with early cervical cancer who wish to preserve their fertility.
  • [MeSH-major] Uterine Cervical Neoplasms / surgery

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  • (PMID = 18829092.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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29. Kornovski Ia, Gorchev G, Trendafilova: [Pregnancy and invasive cervical cancer]. Akush Ginekol (Sofiia); 2008;47(4):44-6
International Agency for Research on Cancer - Screening Group. diagnostics - A practical manual on visual screening for cervical neoplasia .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pregnancy and invasive cervical cancer].
  • A case of 27-year old woman with spinocellular cervical cancer stage IB1 (FIGO) associated with pregnancy (36 g.w.) was reported.
  • The review of the literature revealed an algorithm and and practical recommendations in terms of management of cervical cancer during pregnancy, depending on the stage of the pregnancy and the tumor.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Uterine Cervical Neoplasms / diagnosis


30. Alouini S, Rida K, Mathevet P: Cervical cancer complicating pregnancy: implications of laparoscopic lymphadenectomy. Gynecol Oncol; 2008 Mar;108(3):472-7
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cervical cancer complicating pregnancy: implications of laparoscopic lymphadenectomy.
  • OBJECTIVE: To define a strategy for lymph node staging in cervical carcinoma complicating pregnancy.
  • The FIGO stage of cervical cancer was IB1 for five women, IB2 for two women, and IIIA for one woman.
  • The pelvic lymph nodes were not invaded in 5 patients (4 IB1, 1 IB2).
  • Cancer treatment was delayed for four out of five patients until after fetal extraction.
  • Lymph nodes were involved in three patients (IB1, IB2, IIIA).
  • CONCLUSION: Laparoscopic lymphadenectomy during pregnancy is a safe and effective procedure for lymph node staging in cervical cancer.
  • Pregnant women who do not have lymph node metastasis may benefit from either delayed cancer treatment after fetal extraction or immediate conservative treatment for early stage cancers.
  • [MeSH-major] Lymph Nodes / pathology. Pelvis / pathology. Pregnancy Complications, Neoplastic / pathology. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Adult. Carcinoma, Squamous Cell / pathology. Female. Humans. Infant, Newborn. Laparoscopy / methods. Lymph Node Excision / methods. Lymphatic Metastasis. Male. Neoplasm Staging. Pregnancy. Pregnancy Outcome. Retrospective Studies. Treatment Outcome


31. Plante M, Lau S, Brydon L, Swenerton K, LeBlanc R, Roy M: Neoadjuvant chemotherapy followed by vaginal radical trachelectomy in bulky stage IB1 cervical cancer: case report. Gynecol Oncol; 2006 May;101(2):367-70
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neoadjuvant chemotherapy followed by vaginal radical trachelectomy in bulky stage IB1 cervical cancer: case report.
  • BACKGROUND: We present 3 young women with bulky stage IB1 cervical cancer treated with neoadjuvant chemotherapy followed by laparoscopic pelvic node dissection and vaginal radical trachelectomy.
  • CASES: In the last year, we have treated 3 young women with large cervical lesions who wished to preserve fertility with induction chemotherapy followed by fertility-sparing surgery.
  • A complete pathological response was confirmed by the absence of residual invasive cancer in the three trachelectomy specimens.
  • CONCLUSION: Neoadjuvant chemotherapy followed by a fertility-sparing surgery may become a valuable option for young women with bulky stage IB1 cervical cancer who wish to preserve their fertility potential.
  • [MeSH-major] Uterine Cervical Neoplasms / drug therapy. Uterine Cervical Neoplasms / surgery

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  • [CommentIn] Gynecol Oncol. 2006 Oct;103(1):374; author reply 374-5 [16860854.001]
  • [CommentIn] Gynecol Oncol. 2006 Nov;103(2):763-4; author reply 764-5 [16952390.001]
  • (PMID = 16542714.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Bader AA, Bjelic-Radisic V, Tamussino KF, Pristauz G, Winter R: Recurrence in a Schuchardt incision after Schauta-Amreich radical vaginal hysterectomy for cervical cancer. Int J Gynecol Cancer; 2006 May-Jun;16(3):1479-81
International Agency for Research on Cancer - Screening Group. diagnostics - A practical manual on visual screening for cervical neoplasia .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrence in a Schuchardt incision after Schauta-Amreich radical vaginal hysterectomy for cervical cancer.
  • A Schuchardt incision is frequently performed to facilitate access to the parametrium during radical vaginal hysterectomy for cervical cancer.
  • We report an adenocarcinoma recurrence in a Schuchardt incision 12 months after radical vaginal hysterectomy for FIGO stage IB1 cervical cancer.
  • Histology of the primary tumor had shown a well-differentiated adenocarcinoma and poorly differentiated squamous cell carcinoma of the cervix 2.6 cm in maximum diameter.
  • Cervical cancers can implant and recur in perineal incisions.
  • [MeSH-major] Hysterectomy, Vaginal / adverse effects. Hysterectomy, Vaginal / methods. Neoplasm Recurrence, Local / diagnosis. Uterine Cervical Neoplasms / surgery. Vaginal Neoplasms / secondary
  • [MeSH-minor] Adenocarcinoma / surgery. Adult. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Episiotomy. Fatal Outcome. Female. Humans


33. Traen K, Svane D, Kryger-Baggesen N, Bertelsen K, Mogensen O: Stage Ib cervical cancer during pregnancy: planned delay in treatment--case report. Eur J Gynaecol Oncol; 2006;27(6):615-7
MedlinePlus Health Information. consumer health - Tumors and Pregnancy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stage Ib cervical cancer during pregnancy: planned delay in treatment--case report.
  • Approximately 0.05% of pregnancies are complicated with cervical cancer.
  • Treatment of this malignancy during pregnancy depends on the stage of disease and gestational age at the time of diagnosis.
  • In women with Stage IB cervical cancer immediate treatment, without regard to the pregnancy, is traditionally advocated in the first and second trimester.
  • We present a case of a Stage IB1 cervical cancer, diagnosed during a twin pregnancy, and treated with a planned delay of 19 weeks.
  • We have reviewed the literature and focused on what is known about planned delay in therapy of Stage IB cervical cancer, diagnosed before 30 weeks of gestational age.
  • [MeSH-major] Carcinoma in Situ / surgery. Carcinoma, Squamous Cell / surgery. Pregnancy Complications, Neoplastic / surgery. Uterine Cervical Neoplasms / surgery

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  • (PMID = 17290596.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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34. Xiao Y, Li JD, Shi HL, Liu JH, Feng YL, Li MD: [Predictive value of in vitro MTT assay chemosensitivity test of cytotoxic drug activity in cervical cancer]. Ai Zheng; 2007 Apr;26(4):386-9
Hazardous Substances Data Bank. FLUOROURACIL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Predictive value of in vitro MTT assay chemosensitivity test of cytotoxic drug activity in cervical cancer].
  • BACKGROUND & OBJECTIVE: In recent years, the neoadjuvant chemotherapy for cervical cancer has evoked more and more attention and has been used widely.
  • This study was to investigate the chemosensitivity of cervical cancer cells to antitumor drugs using in vitro MTT assay chemosensitivity test.
  • METHODS: The sensitivity of fresh human cervical cancer cells from 32 patients to 9 cytotoxic drugs was tested using in vitro MTT assay.
  • RESULTS: The cytotoxic activities of the 9 drugs for cervical cancer were in sequence from high to low as follows: liposomal paclitaxel, taxol, carboplatin (CBP), ifosfamide (IFO), etoposide (VP-16), 5-fluorouracil (5-FU), cisplatin (DDP), bleomycin (BLM), and cyclophosphamide (CTX).
  • Generally, cervical cancer cells were more sensitive to paclitaxel, taxol, and CBP than to other drugs (P<0.05) with inhibition rates of 56.56%, 55.66%, and 46.81%, respectively.
  • Stage Ib1 cervical cancer cells were more sensitive to taxol, paclitaxel, and CBP than to other drugs with inhibition rates of 58.71%, 53.00%, and 49.25%, respectively; stage Ib2 cervical cancer cells were more sensitive to paclitaxel and taxol than to other drugs with inhibition rates of 65.26% and 50.06%.
  • Both moderately and poorly differentiated squamous cell cancer cells were more sensitive to taxol, paclitaxel, and CBP than to other drugs with inhibition rates of 52.01%, 49.21%, and 40.02% for the former, and 60.02%, 61.16%, and 48.75% for the latter.
  • CONCLUSIONS: MTT assay, a sensitive and widely used chemosensitivity testing method, is helpful in sensitive drug screening and neoadjuvant chemotherapy regimen selection for cervical cancer.
  • Cervical cancer cells are more sensitive to paclitaxel, taxol, and CBP than to other tested drugs in this study.
  • [MeSH-major] Antineoplastic Agents / pharmacology. Carcinoma, Squamous Cell / pathology. Cell Survival / drug effects. Uterine Cervical Neoplasms / pathology


35. Pahisa J, Martínez-Román S, Martínez-Zamora MA, Torné A, Caparrós X, Sanjuán A, Lejárcegui JA: Laparoscopic ovarian transposition in patients with early cervical cancer. Int J Gynecol Cancer; 2008 May-Jun;18(3):584-9
International Agency for Research on Cancer - Screening Group. diagnostics - Planning and Implementing Cervical Cancer Prevention and Control Programs: A Manual for Managers .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic ovarian transposition in patients with early cervical cancer.
  • The aim of this study was to evaluate the feasibility, efficacy, and morbidity of laparoscopic ovarian transposition on the preservation of hormonal function in patients younger than 45 years operated for early cervical cancer.
  • This prospective study included 28 FIGO stage IB1 cervical cancer patients, 45 years old or younger, maintaining menstrual cycles, who were considered suitable for conservation of the ovaries.
  • According to our results, laparoscopic ovarian transposition is a safe and effective procedure for the preservation of ovarian function in young patients with early cervical cancer undergoing adjuvant radiotherapy after surgery.
  • [MeSH-major] Infertility, Female / prevention & control. Laparoscopy / methods. Ovary / surgery. Radiation Injuries / prevention & control. Uterine Cervical Neoplasms / radiotherapy


36. Gordon AN, Schimp VL: Re: Radical abdominal trachelectomy for (microscopic) stage IB1 cervical cancer at 15-week gestation. Gynecol Oncol; 2010 Jul;118(1):97; author reply 97-8
MedlinePlus Health Information. consumer health - Tumors and Pregnancy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Re: Radical abdominal trachelectomy for (microscopic) stage IB1 cervical cancer at 15-week gestation.
  • [MeSH-major] Pregnancy Complications, Neoplastic / surgery. Uterine Cervical Neoplasms / surgery

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  • [CommentOn] Gynecol Oncol. 2010 Jan;116(1):151-2 [19878979.001]
  • (PMID = 20378158.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
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37. Maneo A, Mangioni C: Re: neoadjuvant chemotheraphy followed by vaginal radical trachelectomy in bulky stage IB1 cervical cancer. Gynecol Oncol; 2006 Nov;103(2):763-4; author reply 764-5
Hazardous Substances Data Bank. IFOSFAMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Re: neoadjuvant chemotheraphy followed by vaginal radical trachelectomy in bulky stage IB1 cervical cancer.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Uterine Cervical Neoplasms / drug therapy

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  • [CommentOn] Gynecol Oncol. 2006 May;101(2):367-70 [16542714.001]
  • (PMID = 16952390.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] P88XT4IS4D / Paclitaxel; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide
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38. Liu H, Peng ZL, Lou JY, Ping W: Pregnancy after neoadjuvant chemotherapy followed by pelvic lymphadenectomy and radical trachelectomy in bulky stage IB1 cervical cancer: a case report. Aust N Z J Obstet Gynaecol; 2008 Oct;48(5):517-8
MedlinePlus Health Information. consumer health - Pregnancy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pregnancy after neoadjuvant chemotherapy followed by pelvic lymphadenectomy and radical trachelectomy in bulky stage IB1 cervical cancer: a case report.
  • [MeSH-major] Hysterectomy / adverse effects. Pregnancy / physiology. Pregnancy Outcome. Uterine Cervical Neoplasms / drug therapy. Uterine Cervical Neoplasms / surgery


39. Bader AA, Winter R, Tamussino KF: Re: Plante M., Lau S., Brydon L., Swenerton K., Leblanc R., Roy M. Neoadjuvant chemotherapy followed by vaginal radical trachelectomy in bulky stage IB1 cervical cancer: case report. Gynecol Oncol 2006;101:367-70. Gynecol Oncol; 2006 Oct;103(1):374; author reply 374-5
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Re: Plante M., Lau S., Brydon L., Swenerton K., Leblanc R., Roy M. Neoadjuvant chemotherapy followed by vaginal radical trachelectomy in bulky stage IB1 cervical cancer: case report. Gynecol Oncol 2006;101:367-70.
  • [MeSH-major] Sentinel Lymph Node Biopsy. Uterine Cervical Neoplasms / drug therapy. Uterine Cervical Neoplasms / surgery






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